ORF_ID e_value Gene_name EC_number CAZy COGs Description
HGCOOKCJ_00005 2e-08
HGCOOKCJ_00012 1.3e-09
HGCOOKCJ_00013 7.8e-08
HGCOOKCJ_00022 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HGCOOKCJ_00023 3.6e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HGCOOKCJ_00024 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
HGCOOKCJ_00025 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HGCOOKCJ_00026 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HGCOOKCJ_00027 9.9e-77 tspO T membrane
HGCOOKCJ_00028 1.8e-206 cotI S Spore coat protein
HGCOOKCJ_00029 1.8e-217 cotSA M Glycosyl transferases group 1
HGCOOKCJ_00030 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
HGCOOKCJ_00032 3.6e-235 ytcC M Glycosyltransferase Family 4
HGCOOKCJ_00033 3.9e-181 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
HGCOOKCJ_00034 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HGCOOKCJ_00035 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
HGCOOKCJ_00036 2.6e-132 dksA T COG1734 DnaK suppressor protein
HGCOOKCJ_00037 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
HGCOOKCJ_00038 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HGCOOKCJ_00039 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HGCOOKCJ_00040 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HGCOOKCJ_00041 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HGCOOKCJ_00042 1.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HGCOOKCJ_00043 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
HGCOOKCJ_00044 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HGCOOKCJ_00045 3.2e-234 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HGCOOKCJ_00046 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HGCOOKCJ_00047 1.1e-24 S Domain of Unknown Function (DUF1540)
HGCOOKCJ_00048 7.3e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HGCOOKCJ_00049 4.7e-249 cydA 1.10.3.14 C oxidase, subunit
HGCOOKCJ_00050 3.6e-41 rpmE2 J Ribosomal protein L31
HGCOOKCJ_00051 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HGCOOKCJ_00052 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HGCOOKCJ_00053 3.6e-73 ytkA S YtkA-like
HGCOOKCJ_00055 2.1e-76 dps P Belongs to the Dps family
HGCOOKCJ_00056 5.4e-63 ytkC S Bacteriophage holin family
HGCOOKCJ_00057 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HGCOOKCJ_00058 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HGCOOKCJ_00059 1.4e-144 ytlC P ABC transporter
HGCOOKCJ_00060 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HGCOOKCJ_00061 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HGCOOKCJ_00062 1.2e-38 ytmB S Protein of unknown function (DUF2584)
HGCOOKCJ_00063 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HGCOOKCJ_00064 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HGCOOKCJ_00065 0.0 asnB 6.3.5.4 E Asparagine synthase
HGCOOKCJ_00066 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HGCOOKCJ_00067 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HGCOOKCJ_00068 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
HGCOOKCJ_00069 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HGCOOKCJ_00070 3.3e-106 ytqB J Putative rRNA methylase
HGCOOKCJ_00071 2.1e-190 yhcC S Fe-S oxidoreductase
HGCOOKCJ_00072 6.7e-41 ytzC S Protein of unknown function (DUF2524)
HGCOOKCJ_00074 5.1e-66 ytrA K GntR family transcriptional regulator
HGCOOKCJ_00075 1.1e-161 ytrB P abc transporter atp-binding protein
HGCOOKCJ_00076 6.1e-169 P ABC-2 family transporter protein
HGCOOKCJ_00077 5.9e-148
HGCOOKCJ_00078 3.1e-127 ytrE V ABC transporter, ATP-binding protein
HGCOOKCJ_00079 8.5e-235 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HGCOOKCJ_00080 5.2e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGCOOKCJ_00081 5.6e-186 T PhoQ Sensor
HGCOOKCJ_00082 1.1e-138 bceA V ABC transporter, ATP-binding protein
HGCOOKCJ_00083 0.0 bceB V ABC transporter (permease)
HGCOOKCJ_00084 1.8e-43 yttA 2.7.13.3 S Pfam Transposase IS66
HGCOOKCJ_00085 2.1e-211 yttB EGP Major facilitator Superfamily
HGCOOKCJ_00086 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HGCOOKCJ_00087 7.7e-55 ytvB S Protein of unknown function (DUF4257)
HGCOOKCJ_00088 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HGCOOKCJ_00089 2.1e-51 ytwF P Sulfurtransferase
HGCOOKCJ_00090 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HGCOOKCJ_00091 1.5e-144 amyC P ABC transporter (permease)
HGCOOKCJ_00092 3.7e-168 amyD P ABC transporter
HGCOOKCJ_00093 2.3e-248 msmE G Bacterial extracellular solute-binding protein
HGCOOKCJ_00094 2.3e-190 msmR K Transcriptional regulator
HGCOOKCJ_00095 1.3e-173 ytaP S Acetyl xylan esterase (AXE1)
HGCOOKCJ_00096 1.6e-142 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HGCOOKCJ_00097 2.4e-261 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HGCOOKCJ_00098 1.4e-220 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HGCOOKCJ_00099 3.7e-128 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HGCOOKCJ_00100 2.2e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HGCOOKCJ_00101 1.9e-225 bioI 1.14.14.46 C Cytochrome P450
HGCOOKCJ_00102 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
HGCOOKCJ_00103 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
HGCOOKCJ_00104 1.2e-290 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
HGCOOKCJ_00105 0.0 ytdP K Transcriptional regulator
HGCOOKCJ_00106 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HGCOOKCJ_00107 4.7e-226 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HGCOOKCJ_00108 4.6e-73 yteS G transport
HGCOOKCJ_00109 9.2e-258 yteT S Oxidoreductase family, C-terminal alpha/beta domain
HGCOOKCJ_00110 4.8e-117 yteU S Integral membrane protein
HGCOOKCJ_00111 3.1e-26 yteV S Sporulation protein Cse60
HGCOOKCJ_00112 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HGCOOKCJ_00113 8.2e-232 ytfP S HI0933-like protein
HGCOOKCJ_00114 1.9e-281 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HGCOOKCJ_00115 2.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HGCOOKCJ_00116 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HGCOOKCJ_00117 4.3e-132 ythP V ABC transporter
HGCOOKCJ_00118 3.9e-207 ythQ U Bacterial ABC transporter protein EcsB
HGCOOKCJ_00119 7.2e-226 pbuO S permease
HGCOOKCJ_00120 7.1e-272 pepV 3.5.1.18 E Dipeptidase
HGCOOKCJ_00121 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HGCOOKCJ_00122 4.3e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HGCOOKCJ_00123 1.3e-165 ytlQ
HGCOOKCJ_00124 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HGCOOKCJ_00125 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HGCOOKCJ_00126 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
HGCOOKCJ_00127 2e-45 ytzH S YtzH-like protein
HGCOOKCJ_00128 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HGCOOKCJ_00129 6.4e-151 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HGCOOKCJ_00130 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
HGCOOKCJ_00131 9.8e-52 ytzB S small secreted protein
HGCOOKCJ_00132 4.7e-207 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HGCOOKCJ_00133 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HGCOOKCJ_00134 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HGCOOKCJ_00135 9.8e-149 ytpQ S Belongs to the UPF0354 family
HGCOOKCJ_00136 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HGCOOKCJ_00137 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HGCOOKCJ_00138 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HGCOOKCJ_00139 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HGCOOKCJ_00140 6.6e-17 ytxH S COG4980 Gas vesicle protein
HGCOOKCJ_00141 4.4e-55 ytxJ O Protein of unknown function (DUF2847)
HGCOOKCJ_00142 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HGCOOKCJ_00143 1.7e-182 ccpA K catabolite control protein A
HGCOOKCJ_00144 7.1e-147 motA N flagellar motor
HGCOOKCJ_00145 1.4e-125 motS N Flagellar motor protein
HGCOOKCJ_00146 1.9e-225 acuC BQ histone deacetylase
HGCOOKCJ_00147 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
HGCOOKCJ_00148 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HGCOOKCJ_00149 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HGCOOKCJ_00150 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HGCOOKCJ_00152 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HGCOOKCJ_00153 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HGCOOKCJ_00154 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
HGCOOKCJ_00155 3.4e-109 yttP K Transcriptional regulator
HGCOOKCJ_00156 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HGCOOKCJ_00157 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HGCOOKCJ_00158 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
HGCOOKCJ_00159 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
HGCOOKCJ_00160 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HGCOOKCJ_00161 2e-29 sspB S spore protein
HGCOOKCJ_00162 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HGCOOKCJ_00163 0.0 ytcJ S amidohydrolase
HGCOOKCJ_00164 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HGCOOKCJ_00165 2.4e-181 sppA OU signal peptide peptidase SppA
HGCOOKCJ_00166 1.3e-87 yteJ S RDD family
HGCOOKCJ_00167 5.6e-116 ytfI S Protein of unknown function (DUF2953)
HGCOOKCJ_00168 8.7e-70 ytfJ S Sporulation protein YtfJ
HGCOOKCJ_00169 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HGCOOKCJ_00170 7e-165 ytxK 2.1.1.72 L DNA methylase
HGCOOKCJ_00171 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HGCOOKCJ_00172 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HGCOOKCJ_00173 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HGCOOKCJ_00174 3.1e-267 argH 4.3.2.1 E argininosuccinate lyase
HGCOOKCJ_00176 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGCOOKCJ_00177 1.7e-130 ytkL S Belongs to the UPF0173 family
HGCOOKCJ_00178 2.9e-173 ytlI K LysR substrate binding domain
HGCOOKCJ_00179 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
HGCOOKCJ_00180 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
HGCOOKCJ_00181 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
HGCOOKCJ_00182 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
HGCOOKCJ_00183 7.6e-121 tcyM U Binding-protein-dependent transport system inner membrane component
HGCOOKCJ_00184 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HGCOOKCJ_00185 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGCOOKCJ_00186 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
HGCOOKCJ_00187 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGCOOKCJ_00188 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
HGCOOKCJ_00189 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
HGCOOKCJ_00190 1.2e-158 ytnM S membrane transporter protein
HGCOOKCJ_00191 8e-241 ytoI K transcriptional regulator containing CBS domains
HGCOOKCJ_00192 2.4e-47 ytpI S YtpI-like protein
HGCOOKCJ_00193 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HGCOOKCJ_00194 9.2e-29
HGCOOKCJ_00195 8.2e-69 ytrI
HGCOOKCJ_00196 3.2e-56 ytrH S Sporulation protein YtrH
HGCOOKCJ_00197 0.0 dnaE 2.7.7.7 L DNA polymerase
HGCOOKCJ_00198 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
HGCOOKCJ_00199 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HGCOOKCJ_00200 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HGCOOKCJ_00201 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HGCOOKCJ_00202 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HGCOOKCJ_00203 1.8e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HGCOOKCJ_00204 2.6e-192 ytvI S sporulation integral membrane protein YtvI
HGCOOKCJ_00205 4.7e-71 yeaL S membrane
HGCOOKCJ_00206 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
HGCOOKCJ_00207 1.8e-242 icd 1.1.1.42 C isocitrate
HGCOOKCJ_00208 1.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HGCOOKCJ_00209 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGCOOKCJ_00210 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
HGCOOKCJ_00211 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HGCOOKCJ_00212 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HGCOOKCJ_00213 1.1e-107 ytaF P Probably functions as a manganese efflux pump
HGCOOKCJ_00214 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HGCOOKCJ_00215 8.9e-161 ytbE S reductase
HGCOOKCJ_00216 4.9e-205 ytbD EGP Major facilitator Superfamily
HGCOOKCJ_00217 9.9e-67 ytcD K Transcriptional regulator
HGCOOKCJ_00218 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HGCOOKCJ_00219 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HGCOOKCJ_00220 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HGCOOKCJ_00221 3.5e-266 dnaB L Membrane attachment protein
HGCOOKCJ_00222 3e-173 dnaI L Primosomal protein DnaI
HGCOOKCJ_00223 4.9e-111 ytxB S SNARE associated Golgi protein
HGCOOKCJ_00224 3.8e-159 ytxC S YtxC-like family
HGCOOKCJ_00225 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HGCOOKCJ_00226 1.5e-149 ysaA S HAD-hyrolase-like
HGCOOKCJ_00227 0.0 lytS 2.7.13.3 T Histidine kinase
HGCOOKCJ_00228 6.3e-131 lytT T COG3279 Response regulator of the LytR AlgR family
HGCOOKCJ_00229 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HGCOOKCJ_00230 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HGCOOKCJ_00232 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HGCOOKCJ_00233 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HGCOOKCJ_00234 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HGCOOKCJ_00235 7.5e-45 ysdA S Membrane
HGCOOKCJ_00236 9.2e-68 ysdB S Sigma-w pathway protein YsdB
HGCOOKCJ_00237 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
HGCOOKCJ_00238 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HGCOOKCJ_00239 1.9e-294 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HGCOOKCJ_00240 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
HGCOOKCJ_00241 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HGCOOKCJ_00242 4.1e-147 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HGCOOKCJ_00243 5e-226 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HGCOOKCJ_00244 2.8e-254 araN G carbohydrate transport
HGCOOKCJ_00245 1.4e-167 araP G carbohydrate transport
HGCOOKCJ_00246 3.4e-144 araQ G transport system permease
HGCOOKCJ_00247 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HGCOOKCJ_00248 0.0 cstA T Carbon starvation protein
HGCOOKCJ_00250 3.6e-38 ysfE 4.4.1.5 E lactoylglutathione lyase activity
HGCOOKCJ_00251 5.6e-258 glcF C Glycolate oxidase
HGCOOKCJ_00252 7.2e-264 glcD 1.1.3.15 C Glycolate oxidase subunit
HGCOOKCJ_00253 4.4e-208 ysfB KT regulator
HGCOOKCJ_00254 2.6e-32 sspI S Belongs to the SspI family
HGCOOKCJ_00255 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HGCOOKCJ_00256 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HGCOOKCJ_00257 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HGCOOKCJ_00258 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HGCOOKCJ_00259 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HGCOOKCJ_00260 1.3e-85 cvpA S membrane protein, required for colicin V production
HGCOOKCJ_00261 0.0 polX L COG1796 DNA polymerase IV (family X)
HGCOOKCJ_00262 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HGCOOKCJ_00263 7.3e-68 yshE S membrane
HGCOOKCJ_00264 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HGCOOKCJ_00265 2.7e-100 fadR K Transcriptional regulator
HGCOOKCJ_00266 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HGCOOKCJ_00267 1.2e-135 etfB C Electron transfer flavoprotein
HGCOOKCJ_00268 4.2e-178 etfA C Electron transfer flavoprotein
HGCOOKCJ_00270 4e-305 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HGCOOKCJ_00271 2e-52 trxA O Belongs to the thioredoxin family
HGCOOKCJ_00272 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HGCOOKCJ_00273 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HGCOOKCJ_00274 1.2e-79 yslB S Protein of unknown function (DUF2507)
HGCOOKCJ_00275 2.4e-107 sdhC C succinate dehydrogenase
HGCOOKCJ_00276 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HGCOOKCJ_00277 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HGCOOKCJ_00278 7.7e-79 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HGCOOKCJ_00279 3.3e-30 gerE K Transcriptional regulator
HGCOOKCJ_00280 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HGCOOKCJ_00281 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HGCOOKCJ_00282 2.9e-196 gerM S COG5401 Spore germination protein
HGCOOKCJ_00283 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HGCOOKCJ_00284 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HGCOOKCJ_00285 1.4e-92 ysnB S Phosphoesterase
HGCOOKCJ_00287 9.1e-134 ysnF S protein conserved in bacteria
HGCOOKCJ_00288 7.6e-82 ysnE K acetyltransferase
HGCOOKCJ_00290 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HGCOOKCJ_00291 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
HGCOOKCJ_00292 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HGCOOKCJ_00293 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HGCOOKCJ_00294 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HGCOOKCJ_00295 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HGCOOKCJ_00296 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HGCOOKCJ_00297 2.3e-187 ysoA H Tetratricopeptide repeat
HGCOOKCJ_00298 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HGCOOKCJ_00299 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HGCOOKCJ_00300 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HGCOOKCJ_00301 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HGCOOKCJ_00302 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
HGCOOKCJ_00303 1.4e-89 ysxD
HGCOOKCJ_00304 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HGCOOKCJ_00305 3.6e-146 hemX O cytochrome C
HGCOOKCJ_00306 3e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HGCOOKCJ_00307 4.4e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HGCOOKCJ_00308 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
HGCOOKCJ_00309 4.6e-249 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HGCOOKCJ_00310 1.9e-226 spoVID M stage VI sporulation protein D
HGCOOKCJ_00311 1.6e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HGCOOKCJ_00312 1.6e-25
HGCOOKCJ_00313 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HGCOOKCJ_00314 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HGCOOKCJ_00315 6.6e-85 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HGCOOKCJ_00316 1.1e-168 spoIIB S Sporulation related domain
HGCOOKCJ_00317 2.8e-102 maf D septum formation protein Maf
HGCOOKCJ_00318 9.8e-68 radC E Belongs to the UPF0758 family
HGCOOKCJ_00319 1.6e-226 S Recombinase
HGCOOKCJ_00320 4.5e-71 S Pfam:Peptidase_M78
HGCOOKCJ_00321 3.4e-63 S sequence-specific DNA binding
HGCOOKCJ_00322 8.8e-09 plcR K helix-turn-helix
HGCOOKCJ_00325 3.5e-21 S Uncharacterized protein YqaH
HGCOOKCJ_00327 2e-92 S DNA protection
HGCOOKCJ_00328 1.5e-164 tadZ D AAA domain
HGCOOKCJ_00330 2.6e-71 S Protein of unknown function (DUF669)
HGCOOKCJ_00331 0.0 S hydrolase activity
HGCOOKCJ_00332 6.2e-65
HGCOOKCJ_00333 7.9e-94 S nuclease activity
HGCOOKCJ_00334 1.2e-80
HGCOOKCJ_00336 1.2e-16 S YopX protein
HGCOOKCJ_00338 1.5e-59
HGCOOKCJ_00342 6.2e-50 V HNH endonuclease
HGCOOKCJ_00343 1.8e-79 L phage terminase small subunit
HGCOOKCJ_00344 1.5e-303 S Terminase
HGCOOKCJ_00345 7.4e-175 S Phage portal protein
HGCOOKCJ_00346 6.8e-81 S peptidase activity
HGCOOKCJ_00347 4.6e-156 gp36 S capsid protein
HGCOOKCJ_00348 3.8e-20
HGCOOKCJ_00349 1.4e-39 S Phage gp6-like head-tail connector protein
HGCOOKCJ_00350 6.1e-38 S Phage head-tail joining protein
HGCOOKCJ_00351 1.4e-50 S Bacteriophage HK97-gp10, putative tail-component
HGCOOKCJ_00353 1.2e-77 S Phage tail tube protein
HGCOOKCJ_00356 0.0 D phage tail tape measure protein
HGCOOKCJ_00357 5.8e-112 S Phage tail protein
HGCOOKCJ_00358 1.4e-221 NU Prophage endopeptidase tail
HGCOOKCJ_00359 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
HGCOOKCJ_00360 2.7e-88
HGCOOKCJ_00361 1e-12
HGCOOKCJ_00363 1.7e-95 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
HGCOOKCJ_00364 6e-57 S Pfam:Phage_holin_4_1
HGCOOKCJ_00365 6.8e-128 xlyB 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
HGCOOKCJ_00366 4.8e-52 S SMI1-KNR4 cell-wall
HGCOOKCJ_00367 4.8e-281 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HGCOOKCJ_00368 1.5e-12
HGCOOKCJ_00373 1e-26 K Helix-turn-helix domain
HGCOOKCJ_00375 7e-51 radC E Belongs to the UPF0758 family
HGCOOKCJ_00376 1.8e-184 mreB D Rod shape-determining protein MreB
HGCOOKCJ_00377 2.8e-157 mreC M Involved in formation and maintenance of cell shape
HGCOOKCJ_00378 1.4e-84 mreD M shape-determining protein
HGCOOKCJ_00379 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HGCOOKCJ_00380 2.5e-144 minD D Belongs to the ParA family
HGCOOKCJ_00381 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HGCOOKCJ_00382 9.2e-161 spoIVFB S Stage IV sporulation protein
HGCOOKCJ_00383 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HGCOOKCJ_00384 4.1e-56 ysxB J ribosomal protein
HGCOOKCJ_00385 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HGCOOKCJ_00386 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HGCOOKCJ_00387 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HGCOOKCJ_00388 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HGCOOKCJ_00389 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
HGCOOKCJ_00390 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
HGCOOKCJ_00391 1.2e-230 nifS 2.8.1.7 E Cysteine desulfurase
HGCOOKCJ_00392 2.7e-307 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HGCOOKCJ_00393 5.4e-161 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HGCOOKCJ_00394 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HGCOOKCJ_00395 9.8e-158 safA M spore coat assembly protein SafA
HGCOOKCJ_00396 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HGCOOKCJ_00397 1.9e-127 yebC K transcriptional regulatory protein
HGCOOKCJ_00398 1.8e-262 alsT E Sodium alanine symporter
HGCOOKCJ_00399 2.6e-35 S Family of unknown function (DUF5412)
HGCOOKCJ_00401 6.5e-119 yrzF T serine threonine protein kinase
HGCOOKCJ_00402 1.3e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HGCOOKCJ_00403 5.3e-253 csbX EGP Major facilitator Superfamily
HGCOOKCJ_00404 4.8e-93 bofC S BofC C-terminal domain
HGCOOKCJ_00405 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HGCOOKCJ_00406 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HGCOOKCJ_00407 2.6e-18 yrzS S Protein of unknown function (DUF2905)
HGCOOKCJ_00408 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HGCOOKCJ_00409 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HGCOOKCJ_00410 1.1e-38 yajC U Preprotein translocase subunit YajC
HGCOOKCJ_00411 1.2e-74 yrzE S Protein of unknown function (DUF3792)
HGCOOKCJ_00412 2.2e-114 yrbG S membrane
HGCOOKCJ_00413 5.7e-270 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HGCOOKCJ_00414 9.4e-49 yrzD S Post-transcriptional regulator
HGCOOKCJ_00415 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HGCOOKCJ_00416 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HGCOOKCJ_00417 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
HGCOOKCJ_00418 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HGCOOKCJ_00419 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HGCOOKCJ_00420 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HGCOOKCJ_00421 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HGCOOKCJ_00422 3.9e-263 lytH 3.5.1.28 M COG3103 SH3 domain protein
HGCOOKCJ_00424 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
HGCOOKCJ_00425 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HGCOOKCJ_00426 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HGCOOKCJ_00427 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HGCOOKCJ_00428 1.2e-70 cymR K Transcriptional regulator
HGCOOKCJ_00429 4.7e-213 iscS 2.8.1.7 E Cysteine desulfurase
HGCOOKCJ_00430 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HGCOOKCJ_00431 1.4e-15 S COG0457 FOG TPR repeat
HGCOOKCJ_00432 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HGCOOKCJ_00433 1.8e-83 yrrD S protein conserved in bacteria
HGCOOKCJ_00434 9.8e-31 yrzR
HGCOOKCJ_00435 8e-08 S Protein of unknown function (DUF3918)
HGCOOKCJ_00436 7.6e-107 glnP P ABC transporter
HGCOOKCJ_00437 3.6e-109 gluC P ABC transporter
HGCOOKCJ_00438 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
HGCOOKCJ_00439 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HGCOOKCJ_00440 2.7e-170 yrrI S AI-2E family transporter
HGCOOKCJ_00441 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HGCOOKCJ_00442 1.7e-41 yrzL S Belongs to the UPF0297 family
HGCOOKCJ_00443 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HGCOOKCJ_00444 1.2e-45 yrzB S Belongs to the UPF0473 family
HGCOOKCJ_00445 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HGCOOKCJ_00446 5.9e-120 yrrM 2.1.1.104 S O-methyltransferase
HGCOOKCJ_00447 7.8e-174 yegQ O Peptidase U32
HGCOOKCJ_00448 2.7e-246 yegQ O COG0826 Collagenase and related proteases
HGCOOKCJ_00449 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HGCOOKCJ_00450 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HGCOOKCJ_00451 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
HGCOOKCJ_00452 4.2e-63 yrrS S Protein of unknown function (DUF1510)
HGCOOKCJ_00453 3.5e-26 yrzA S Protein of unknown function (DUF2536)
HGCOOKCJ_00454 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HGCOOKCJ_00455 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HGCOOKCJ_00456 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HGCOOKCJ_00457 2.6e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HGCOOKCJ_00458 4.6e-35 yrhC S YrhC-like protein
HGCOOKCJ_00459 1.4e-78 yrhD S Protein of unknown function (DUF1641)
HGCOOKCJ_00460 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HGCOOKCJ_00461 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
HGCOOKCJ_00462 1.8e-142 focA P Formate nitrite
HGCOOKCJ_00465 4.5e-97 yrhH Q methyltransferase
HGCOOKCJ_00466 4.8e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HGCOOKCJ_00467 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HGCOOKCJ_00468 1.5e-46 yrhK S YrhK-like protein
HGCOOKCJ_00469 0.0 yrhL I Acyltransferase family
HGCOOKCJ_00470 1.7e-151 rsiV S Protein of unknown function (DUF3298)
HGCOOKCJ_00471 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HGCOOKCJ_00472 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
HGCOOKCJ_00473 3.6e-106 yrhP E LysE type translocator
HGCOOKCJ_00474 1.6e-255 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HGCOOKCJ_00475 0.0 levR K PTS system fructose IIA component
HGCOOKCJ_00476 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
HGCOOKCJ_00477 8.2e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
HGCOOKCJ_00478 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HGCOOKCJ_00479 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HGCOOKCJ_00480 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HGCOOKCJ_00481 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
HGCOOKCJ_00482 1.9e-200 adhA 1.1.1.1 C alcohol dehydrogenase
HGCOOKCJ_00483 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
HGCOOKCJ_00484 4.3e-47 yraB K helix_turn_helix, mercury resistance
HGCOOKCJ_00485 1.1e-49 yraD M Spore coat protein
HGCOOKCJ_00486 2.6e-26 yraE
HGCOOKCJ_00487 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HGCOOKCJ_00488 6.4e-63 yraF M Spore coat protein
HGCOOKCJ_00489 5.3e-37 yraG
HGCOOKCJ_00490 1.3e-66 E Glyoxalase-like domain
HGCOOKCJ_00491 2.4e-61 T sh3 domain protein
HGCOOKCJ_00492 1.7e-60 T sh3 domain protein
HGCOOKCJ_00493 3.2e-155 S Alpha beta hydrolase
HGCOOKCJ_00494 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGCOOKCJ_00495 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HGCOOKCJ_00497 2.4e-206 yraM S PrpF protein
HGCOOKCJ_00498 1.2e-163 yraN K Transcriptional regulator
HGCOOKCJ_00499 9.5e-226 yraO C Citrate transporter
HGCOOKCJ_00500 4.5e-188 yrpG C Aldo/keto reductase family
HGCOOKCJ_00501 6.3e-96 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
HGCOOKCJ_00502 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HGCOOKCJ_00504 3e-125 yrpD S Domain of unknown function, YrpD
HGCOOKCJ_00505 7.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HGCOOKCJ_00506 1.5e-194 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HGCOOKCJ_00507 7.6e-168 aadK G Streptomycin adenylyltransferase
HGCOOKCJ_00508 1.2e-91 yrdA S DinB family
HGCOOKCJ_00509 1.9e-57 S Protein of unknown function (DUF2568)
HGCOOKCJ_00510 3.1e-101 yrdC 3.5.1.19 Q Isochorismatase family
HGCOOKCJ_00511 4.1e-231 cypA C Cytochrome P450
HGCOOKCJ_00512 4.1e-46 yrdF K ribonuclease inhibitor
HGCOOKCJ_00513 2.2e-79 bkdR K helix_turn_helix ASNC type
HGCOOKCJ_00514 3.3e-138 azlC E AzlC protein
HGCOOKCJ_00515 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
HGCOOKCJ_00516 1.5e-231 brnQ E Component of the transport system for branched-chain amino acids
HGCOOKCJ_00518 7.7e-163 gltR K LysR substrate binding domain
HGCOOKCJ_00519 1.3e-66 yodA S tautomerase
HGCOOKCJ_00520 3.5e-158 czcD P COG1230 Co Zn Cd efflux system component
HGCOOKCJ_00521 2e-199 trkA P Oxidoreductase
HGCOOKCJ_00522 5.9e-160 yrdQ K Transcriptional regulator
HGCOOKCJ_00523 1.7e-171 yrdR EG EamA-like transporter family
HGCOOKCJ_00524 2.1e-17 S YrzO-like protein
HGCOOKCJ_00525 4.5e-236 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HGCOOKCJ_00526 1.4e-83 bltD 2.3.1.57 K FR47-like protein
HGCOOKCJ_00527 3.5e-211 blt EGP Major facilitator Superfamily
HGCOOKCJ_00528 4.8e-151 bltR K helix_turn_helix, mercury resistance
HGCOOKCJ_00529 2.6e-108 yrkC G Cupin domain
HGCOOKCJ_00530 7.8e-39 yrkD S protein conserved in bacteria
HGCOOKCJ_00531 5.1e-84 yrkE O DsrE/DsrF/DrsH-like family
HGCOOKCJ_00532 1.7e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
HGCOOKCJ_00533 2.3e-212 yrkH P Rhodanese Homology Domain
HGCOOKCJ_00534 2.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
HGCOOKCJ_00535 4.3e-117 yrkJ S membrane transporter protein
HGCOOKCJ_00536 2.8e-79 S Protein of unknown function with HXXEE motif
HGCOOKCJ_00537 1.5e-97 ywrO S Flavodoxin-like fold
HGCOOKCJ_00538 6e-105 yrkN K Acetyltransferase (GNAT) family
HGCOOKCJ_00539 8.2e-224 yrkO P Protein of unknown function (DUF418)
HGCOOKCJ_00540 1.1e-127 T Transcriptional regulator
HGCOOKCJ_00541 9e-237 yrkQ T Histidine kinase
HGCOOKCJ_00542 2e-68 psiE S Protein PsiE homolog
HGCOOKCJ_00543 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGCOOKCJ_00544 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
HGCOOKCJ_00545 2.3e-133 yqeB
HGCOOKCJ_00546 1.2e-171 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
HGCOOKCJ_00547 4.7e-106 yqeD S SNARE associated Golgi protein
HGCOOKCJ_00548 2.1e-137 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HGCOOKCJ_00549 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
HGCOOKCJ_00551 5.3e-95 yqeG S hydrolase of the HAD superfamily
HGCOOKCJ_00552 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HGCOOKCJ_00553 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HGCOOKCJ_00554 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HGCOOKCJ_00555 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HGCOOKCJ_00556 7.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HGCOOKCJ_00557 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HGCOOKCJ_00558 2.9e-139 yqeM Q Methyltransferase
HGCOOKCJ_00559 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HGCOOKCJ_00560 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
HGCOOKCJ_00561 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
HGCOOKCJ_00562 0.0 comEC S Competence protein ComEC
HGCOOKCJ_00563 4.1e-15 S YqzM-like protein
HGCOOKCJ_00564 1.1e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
HGCOOKCJ_00565 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
HGCOOKCJ_00566 1.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HGCOOKCJ_00567 6.9e-223 spoIIP M stage II sporulation protein P
HGCOOKCJ_00568 1e-54 yqxA S Protein of unknown function (DUF3679)
HGCOOKCJ_00569 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HGCOOKCJ_00570 4.8e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
HGCOOKCJ_00571 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HGCOOKCJ_00572 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HGCOOKCJ_00573 0.0 dnaK O Heat shock 70 kDa protein
HGCOOKCJ_00574 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HGCOOKCJ_00575 5.4e-175 prmA J Methylates ribosomal protein L11
HGCOOKCJ_00576 1.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HGCOOKCJ_00577 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HGCOOKCJ_00578 1.6e-158 yqeW P COG1283 Na phosphate symporter
HGCOOKCJ_00579 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HGCOOKCJ_00580 2.5e-61 yqeY S Yqey-like protein
HGCOOKCJ_00581 5.4e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HGCOOKCJ_00582 4.3e-122 yqfA S UPF0365 protein
HGCOOKCJ_00583 6e-25 yqfB
HGCOOKCJ_00584 2.7e-45 yqfC S sporulation protein YqfC
HGCOOKCJ_00585 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HGCOOKCJ_00586 1.1e-175 phoH T Phosphate starvation-inducible protein PhoH
HGCOOKCJ_00588 0.0 yqfF S membrane-associated HD superfamily hydrolase
HGCOOKCJ_00589 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HGCOOKCJ_00590 1.6e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HGCOOKCJ_00591 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HGCOOKCJ_00592 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HGCOOKCJ_00593 8.4e-19 S YqzL-like protein
HGCOOKCJ_00594 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
HGCOOKCJ_00595 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HGCOOKCJ_00596 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HGCOOKCJ_00597 4.5e-112 ccpN K CBS domain
HGCOOKCJ_00598 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HGCOOKCJ_00599 4.5e-88 yaiI S Belongs to the UPF0178 family
HGCOOKCJ_00600 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HGCOOKCJ_00601 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HGCOOKCJ_00602 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
HGCOOKCJ_00603 6.1e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
HGCOOKCJ_00604 5.1e-212 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HGCOOKCJ_00605 2.6e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HGCOOKCJ_00606 2.9e-14 yqfQ S YqfQ-like protein
HGCOOKCJ_00607 1.7e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HGCOOKCJ_00608 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HGCOOKCJ_00609 2.1e-36 yqfT S Protein of unknown function (DUF2624)
HGCOOKCJ_00610 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HGCOOKCJ_00611 1.9e-77 zur P Belongs to the Fur family
HGCOOKCJ_00612 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HGCOOKCJ_00613 4.3e-62 yqfX S membrane
HGCOOKCJ_00614 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HGCOOKCJ_00615 5.2e-47 yqfZ M LysM domain
HGCOOKCJ_00616 2.2e-75 yqgA
HGCOOKCJ_00617 8.5e-134 yqgB S Protein of unknown function (DUF1189)
HGCOOKCJ_00618 4e-73 yqgC S protein conserved in bacteria
HGCOOKCJ_00619 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HGCOOKCJ_00620 2.5e-231 yqgE EGP Major facilitator superfamily
HGCOOKCJ_00621 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HGCOOKCJ_00622 5.3e-151 pstS P Phosphate
HGCOOKCJ_00623 1.3e-160 pstC P probably responsible for the translocation of the substrate across the membrane
HGCOOKCJ_00624 4.4e-158 pstA P Phosphate transport system permease
HGCOOKCJ_00625 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HGCOOKCJ_00626 9.8e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HGCOOKCJ_00627 1.9e-75 yqzC S YceG-like family
HGCOOKCJ_00628 9.2e-51 yqzD
HGCOOKCJ_00630 3.2e-203 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
HGCOOKCJ_00631 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HGCOOKCJ_00632 2.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HGCOOKCJ_00633 2.5e-09 yqgO
HGCOOKCJ_00634 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HGCOOKCJ_00635 3.1e-33 yqgQ S Protein conserved in bacteria
HGCOOKCJ_00636 5.2e-181 glcK 2.7.1.2 G Glucokinase
HGCOOKCJ_00637 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HGCOOKCJ_00638 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HGCOOKCJ_00639 2.7e-199 yqgU
HGCOOKCJ_00640 6.9e-50 yqgV S Thiamine-binding protein
HGCOOKCJ_00641 8.9e-23 yqgW S Protein of unknown function (DUF2759)
HGCOOKCJ_00642 1.9e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HGCOOKCJ_00643 1.8e-37 yqgY S Protein of unknown function (DUF2626)
HGCOOKCJ_00644 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
HGCOOKCJ_00646 1.7e-151 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HGCOOKCJ_00647 5.2e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HGCOOKCJ_00648 7.2e-175 corA P Mg2 transporter protein
HGCOOKCJ_00650 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HGCOOKCJ_00651 1.6e-175 comGB NU COG1459 Type II secretory pathway, component PulF
HGCOOKCJ_00652 1.4e-47 comGC U Required for transformation and DNA binding
HGCOOKCJ_00653 4.4e-71 gspH NU protein transport across the cell outer membrane
HGCOOKCJ_00654 1.1e-59 comGE
HGCOOKCJ_00655 5.5e-49 comGF U Putative Competence protein ComGF
HGCOOKCJ_00656 3.7e-42 S ComG operon protein 7
HGCOOKCJ_00657 1.4e-26 yqzE S YqzE-like protein
HGCOOKCJ_00658 7.3e-54 yqzG S Protein of unknown function (DUF3889)
HGCOOKCJ_00659 2.1e-116 yqxM
HGCOOKCJ_00660 6.7e-59 sipW 3.4.21.89 U Signal peptidase
HGCOOKCJ_00661 2.3e-142 tasA S Cell division protein FtsN
HGCOOKCJ_00662 1e-54 sinR K transcriptional
HGCOOKCJ_00663 1.2e-24 sinI S Anti-repressor SinI
HGCOOKCJ_00664 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
HGCOOKCJ_00665 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HGCOOKCJ_00666 9.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HGCOOKCJ_00667 3.4e-255 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HGCOOKCJ_00668 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HGCOOKCJ_00669 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
HGCOOKCJ_00670 5.2e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HGCOOKCJ_00671 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HGCOOKCJ_00672 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
HGCOOKCJ_00673 2.2e-61 yqhP
HGCOOKCJ_00674 2.1e-174 yqhQ S Protein of unknown function (DUF1385)
HGCOOKCJ_00675 2.3e-93 yqhR S Conserved membrane protein YqhR
HGCOOKCJ_00676 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HGCOOKCJ_00677 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HGCOOKCJ_00678 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HGCOOKCJ_00679 7.9e-37 yqhV S Protein of unknown function (DUF2619)
HGCOOKCJ_00680 1.2e-171 spoIIIAA S stage III sporulation protein AA
HGCOOKCJ_00681 2.9e-85 spoIIIAB S Stage III sporulation protein
HGCOOKCJ_00682 7.6e-29 spoIIIAC S stage III sporulation protein AC
HGCOOKCJ_00683 2.3e-58 spoIIIAD S Stage III sporulation protein AD
HGCOOKCJ_00684 1.3e-197 spoIIIAE S stage III sporulation protein AE
HGCOOKCJ_00685 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HGCOOKCJ_00686 6.9e-103 spoIIIAG S stage III sporulation protein AG
HGCOOKCJ_00687 9.9e-91 spoIIIAH S SpoIIIAH-like protein
HGCOOKCJ_00688 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HGCOOKCJ_00689 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HGCOOKCJ_00690 2.1e-67 yqhY S protein conserved in bacteria
HGCOOKCJ_00691 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HGCOOKCJ_00692 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HGCOOKCJ_00693 2.2e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HGCOOKCJ_00694 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HGCOOKCJ_00695 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HGCOOKCJ_00696 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HGCOOKCJ_00697 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HGCOOKCJ_00698 1.7e-78 argR K Regulates arginine biosynthesis genes
HGCOOKCJ_00699 0.0 recN L May be involved in recombinational repair of damaged DNA
HGCOOKCJ_00700 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
HGCOOKCJ_00701 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HGCOOKCJ_00703 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HGCOOKCJ_00704 5.9e-27
HGCOOKCJ_00705 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
HGCOOKCJ_00706 1.8e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HGCOOKCJ_00707 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
HGCOOKCJ_00708 4.7e-157 hbdA 1.1.1.157 I Dehydrogenase
HGCOOKCJ_00709 1.8e-212 mmgC I acyl-CoA dehydrogenase
HGCOOKCJ_00710 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HGCOOKCJ_00711 5.7e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HGCOOKCJ_00712 7.1e-164 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HGCOOKCJ_00713 4e-34 yqzF S Protein of unknown function (DUF2627)
HGCOOKCJ_00714 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
HGCOOKCJ_00715 7.1e-156 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
HGCOOKCJ_00716 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HGCOOKCJ_00717 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
HGCOOKCJ_00718 3.4e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HGCOOKCJ_00719 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HGCOOKCJ_00720 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HGCOOKCJ_00721 3.5e-233 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HGCOOKCJ_00722 2.6e-152 bmrR K helix_turn_helix, mercury resistance
HGCOOKCJ_00723 7.9e-208 norA EGP Major facilitator Superfamily
HGCOOKCJ_00724 8.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HGCOOKCJ_00725 9.3e-77 yqiW S Belongs to the UPF0403 family
HGCOOKCJ_00726 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
HGCOOKCJ_00727 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
HGCOOKCJ_00728 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HGCOOKCJ_00729 1.1e-175 yqjA S Putative aromatic acid exporter C-terminal domain
HGCOOKCJ_00730 1.4e-98 yqjB S protein conserved in bacteria
HGCOOKCJ_00732 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HGCOOKCJ_00733 4.4e-291 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HGCOOKCJ_00734 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HGCOOKCJ_00735 3.6e-142 yqjF S Uncharacterized conserved protein (COG2071)
HGCOOKCJ_00736 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HGCOOKCJ_00737 4.5e-24 yqzJ
HGCOOKCJ_00738 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HGCOOKCJ_00739 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HGCOOKCJ_00740 1.6e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HGCOOKCJ_00741 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HGCOOKCJ_00742 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HGCOOKCJ_00743 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HGCOOKCJ_00744 0.0 rocB E arginine degradation protein
HGCOOKCJ_00745 8.6e-148 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HGCOOKCJ_00746 3.4e-180 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HGCOOKCJ_00747 3.5e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HGCOOKCJ_00748 2.4e-264 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HGCOOKCJ_00749 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
HGCOOKCJ_00750 7.2e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGCOOKCJ_00752 5.2e-226 yqjV G Major Facilitator Superfamily
HGCOOKCJ_00754 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HGCOOKCJ_00755 2.2e-49 S YolD-like protein
HGCOOKCJ_00756 3.6e-87 yqjY K acetyltransferase
HGCOOKCJ_00757 8e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
HGCOOKCJ_00758 4.7e-196 yqkA K GrpB protein
HGCOOKCJ_00759 2.8e-54 yqkB S Belongs to the HesB IscA family
HGCOOKCJ_00760 9.4e-39 yqkC S Protein of unknown function (DUF2552)
HGCOOKCJ_00761 2.4e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HGCOOKCJ_00762 4e-14 yqkE S Protein of unknown function (DUF3886)
HGCOOKCJ_00763 4.4e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HGCOOKCJ_00765 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HGCOOKCJ_00766 3e-223 yqxK 3.6.4.12 L DNA helicase
HGCOOKCJ_00767 4.5e-58 ansR K Transcriptional regulator
HGCOOKCJ_00768 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
HGCOOKCJ_00769 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HGCOOKCJ_00770 3.1e-235 mleN C Na H antiporter
HGCOOKCJ_00771 5.5e-242 mleA 1.1.1.38 C malic enzyme
HGCOOKCJ_00772 2e-32 yqkK
HGCOOKCJ_00773 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HGCOOKCJ_00774 2.4e-80 fur P Belongs to the Fur family
HGCOOKCJ_00775 3.7e-37 S Protein of unknown function (DUF4227)
HGCOOKCJ_00776 2.6e-166 xerD L recombinase XerD
HGCOOKCJ_00777 1.2e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HGCOOKCJ_00778 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HGCOOKCJ_00779 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HGCOOKCJ_00780 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HGCOOKCJ_00781 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HGCOOKCJ_00782 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGCOOKCJ_00783 7.4e-112 spoVAA S Stage V sporulation protein AA
HGCOOKCJ_00784 1e-67 spoVAB S Stage V sporulation protein AB
HGCOOKCJ_00785 2.3e-78 spoVAC S stage V sporulation protein AC
HGCOOKCJ_00786 9e-192 spoVAD I Stage V sporulation protein AD
HGCOOKCJ_00787 2.2e-57 spoVAEB S stage V sporulation protein
HGCOOKCJ_00788 1.4e-110 spoVAEA S stage V sporulation protein
HGCOOKCJ_00789 1.4e-273 spoVAF EG Stage V sporulation protein AF
HGCOOKCJ_00790 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HGCOOKCJ_00791 1.3e-149 ypuA S Secreted protein
HGCOOKCJ_00792 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HGCOOKCJ_00795 1.5e-17 S SNARE associated Golgi protein
HGCOOKCJ_00796 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
HGCOOKCJ_00797 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HGCOOKCJ_00798 6e-55 ypuD
HGCOOKCJ_00799 1.3e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HGCOOKCJ_00800 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
HGCOOKCJ_00801 9.8e-230 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HGCOOKCJ_00802 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HGCOOKCJ_00803 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGCOOKCJ_00804 4.5e-94 ypuF S Domain of unknown function (DUF309)
HGCOOKCJ_00805 4.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HGCOOKCJ_00806 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HGCOOKCJ_00807 4e-98 ypuI S Protein of unknown function (DUF3907)
HGCOOKCJ_00808 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HGCOOKCJ_00809 3.5e-103 spmA S Spore maturation protein
HGCOOKCJ_00810 1.9e-87 spmB S Spore maturation protein
HGCOOKCJ_00811 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HGCOOKCJ_00812 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HGCOOKCJ_00813 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HGCOOKCJ_00814 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HGCOOKCJ_00815 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGCOOKCJ_00816 0.0 resE 2.7.13.3 T Histidine kinase
HGCOOKCJ_00817 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
HGCOOKCJ_00818 6.8e-201 rsiX
HGCOOKCJ_00819 9e-136 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HGCOOKCJ_00820 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGCOOKCJ_00821 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HGCOOKCJ_00822 4.7e-41 fer C Ferredoxin
HGCOOKCJ_00823 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
HGCOOKCJ_00824 3.2e-286 recQ 3.6.4.12 L DNA helicase
HGCOOKCJ_00825 2.2e-100 ypbD S metal-dependent membrane protease
HGCOOKCJ_00826 4.6e-81 ypbE M Lysin motif
HGCOOKCJ_00827 2.8e-81 ypbF S Protein of unknown function (DUF2663)
HGCOOKCJ_00828 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
HGCOOKCJ_00829 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HGCOOKCJ_00830 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HGCOOKCJ_00831 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HGCOOKCJ_00832 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
HGCOOKCJ_00833 4.7e-155 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HGCOOKCJ_00834 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HGCOOKCJ_00835 9.2e-113 ypfA M Flagellar protein YcgR
HGCOOKCJ_00836 1.8e-23 S Family of unknown function (DUF5359)
HGCOOKCJ_00837 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HGCOOKCJ_00838 4.3e-206 rpsA 1.17.7.4 J Ribosomal protein S1
HGCOOKCJ_00839 4.1e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HGCOOKCJ_00840 1e-07 S YpzI-like protein
HGCOOKCJ_00841 1.3e-102 yphA
HGCOOKCJ_00842 2.5e-161 seaA S YIEGIA protein
HGCOOKCJ_00843 1.6e-28 ypzH
HGCOOKCJ_00844 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HGCOOKCJ_00845 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HGCOOKCJ_00846 1.6e-18 yphE S Protein of unknown function (DUF2768)
HGCOOKCJ_00847 5.4e-138 yphF
HGCOOKCJ_00848 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HGCOOKCJ_00849 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HGCOOKCJ_00850 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
HGCOOKCJ_00851 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HGCOOKCJ_00852 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HGCOOKCJ_00853 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HGCOOKCJ_00854 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HGCOOKCJ_00855 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HGCOOKCJ_00856 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HGCOOKCJ_00857 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HGCOOKCJ_00858 8.1e-207 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HGCOOKCJ_00859 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HGCOOKCJ_00860 6.6e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HGCOOKCJ_00861 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HGCOOKCJ_00862 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HGCOOKCJ_00863 6.5e-119 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HGCOOKCJ_00864 4e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HGCOOKCJ_00865 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HGCOOKCJ_00866 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HGCOOKCJ_00867 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HGCOOKCJ_00868 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HGCOOKCJ_00869 4.1e-234 S COG0457 FOG TPR repeat
HGCOOKCJ_00870 2.8e-99 ypiB S Belongs to the UPF0302 family
HGCOOKCJ_00871 8.5e-78 ypiF S Protein of unknown function (DUF2487)
HGCOOKCJ_00872 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
HGCOOKCJ_00873 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
HGCOOKCJ_00874 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HGCOOKCJ_00875 4.4e-98 ypjA S membrane
HGCOOKCJ_00876 6.1e-143 ypjB S sporulation protein
HGCOOKCJ_00877 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HGCOOKCJ_00878 3.1e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HGCOOKCJ_00879 6.3e-148 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HGCOOKCJ_00880 6.5e-72 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HGCOOKCJ_00881 6.9e-130 bshB1 S proteins, LmbE homologs
HGCOOKCJ_00882 3.7e-210 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HGCOOKCJ_00883 4.4e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HGCOOKCJ_00884 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HGCOOKCJ_00885 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HGCOOKCJ_00886 1.2e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HGCOOKCJ_00887 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HGCOOKCJ_00888 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HGCOOKCJ_00889 6.7e-23 ypmA S Protein of unknown function (DUF4264)
HGCOOKCJ_00890 3.4e-80 ypmB S protein conserved in bacteria
HGCOOKCJ_00891 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HGCOOKCJ_00892 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
HGCOOKCJ_00893 5.7e-129 dnaD L DNA replication protein DnaD
HGCOOKCJ_00894 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HGCOOKCJ_00895 4.7e-93 ypoC
HGCOOKCJ_00896 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
HGCOOKCJ_00897 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HGCOOKCJ_00898 2.6e-188 yppC S Protein of unknown function (DUF2515)
HGCOOKCJ_00901 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
HGCOOKCJ_00903 1.2e-48 yppG S YppG-like protein
HGCOOKCJ_00904 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
HGCOOKCJ_00905 1.9e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HGCOOKCJ_00906 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HGCOOKCJ_00907 1.3e-237 yprB L RNase_H superfamily
HGCOOKCJ_00908 3.3e-92 ypsA S Belongs to the UPF0398 family
HGCOOKCJ_00909 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HGCOOKCJ_00910 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HGCOOKCJ_00912 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
HGCOOKCJ_00913 7.1e-133 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGCOOKCJ_00914 1.7e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HGCOOKCJ_00915 3.9e-187 ptxS K transcriptional
HGCOOKCJ_00916 2.9e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HGCOOKCJ_00917 7e-104 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
HGCOOKCJ_00918 5e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HGCOOKCJ_00919 4.2e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HGCOOKCJ_00920 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HGCOOKCJ_00921 1.6e-228 pbuX F xanthine
HGCOOKCJ_00922 4.4e-208 bcsA Q Naringenin-chalcone synthase
HGCOOKCJ_00923 5.1e-87 ypbQ S protein conserved in bacteria
HGCOOKCJ_00924 0.0 ypbR S Dynamin family
HGCOOKCJ_00925 1e-38 ypbS S Protein of unknown function (DUF2533)
HGCOOKCJ_00926 2e-07
HGCOOKCJ_00927 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
HGCOOKCJ_00929 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
HGCOOKCJ_00930 5.4e-107 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HGCOOKCJ_00931 8.9e-127 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
HGCOOKCJ_00932 2.6e-27 ypeQ S Zinc-finger
HGCOOKCJ_00933 8.1e-31 S Protein of unknown function (DUF2564)
HGCOOKCJ_00934 3.8e-16 degR
HGCOOKCJ_00935 7.9e-31 cspD K Cold-shock protein
HGCOOKCJ_00936 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HGCOOKCJ_00937 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HGCOOKCJ_00938 2.3e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HGCOOKCJ_00939 3.1e-110 ypgQ S phosphohydrolase
HGCOOKCJ_00940 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
HGCOOKCJ_00941 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HGCOOKCJ_00942 1.7e-75 yphP S Belongs to the UPF0403 family
HGCOOKCJ_00943 1.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
HGCOOKCJ_00944 7.8e-114 ypjP S YpjP-like protein
HGCOOKCJ_00945 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HGCOOKCJ_00946 4.3e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HGCOOKCJ_00947 7.9e-96 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HGCOOKCJ_00948 7.4e-112 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HGCOOKCJ_00949 4.2e-110 hlyIII S protein, Hemolysin III
HGCOOKCJ_00950 1.6e-185 pspF K Transcriptional regulator
HGCOOKCJ_00951 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HGCOOKCJ_00952 3.1e-40 ypmP S Protein of unknown function (DUF2535)
HGCOOKCJ_00953 3.2e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HGCOOKCJ_00954 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
HGCOOKCJ_00955 5e-99 ypmS S protein conserved in bacteria
HGCOOKCJ_00956 5.5e-29 ypmT S Uncharacterized ympT
HGCOOKCJ_00957 2.6e-223 mepA V MATE efflux family protein
HGCOOKCJ_00958 1.6e-70 ypoP K transcriptional
HGCOOKCJ_00959 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HGCOOKCJ_00960 1.4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HGCOOKCJ_00961 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
HGCOOKCJ_00962 3.6e-213 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HGCOOKCJ_00963 3.3e-188 cgeB S Spore maturation protein
HGCOOKCJ_00964 1.2e-65 cgeA
HGCOOKCJ_00965 3.5e-38 cgeC
HGCOOKCJ_00966 1e-256 cgeD M maturation of the outermost layer of the spore
HGCOOKCJ_00967 2.9e-145 yiiD K acetyltransferase
HGCOOKCJ_00970 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HGCOOKCJ_00971 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HGCOOKCJ_00972 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HGCOOKCJ_00973 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
HGCOOKCJ_00974 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
HGCOOKCJ_00975 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
HGCOOKCJ_00976 2.9e-47 yokU S YokU-like protein, putative antitoxin
HGCOOKCJ_00977 1.4e-36 yozE S Belongs to the UPF0346 family
HGCOOKCJ_00978 1.4e-124 yodN
HGCOOKCJ_00980 2.8e-24 yozD S YozD-like protein
HGCOOKCJ_00981 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
HGCOOKCJ_00982 3.6e-54 yodL S YodL-like
HGCOOKCJ_00983 5.3e-09
HGCOOKCJ_00984 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HGCOOKCJ_00985 2.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HGCOOKCJ_00986 5.2e-24 yodI
HGCOOKCJ_00987 1.7e-128 yodH Q Methyltransferase
HGCOOKCJ_00988 1.9e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HGCOOKCJ_00989 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HGCOOKCJ_00990 6.2e-28 S Protein of unknown function (DUF3311)
HGCOOKCJ_00991 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
HGCOOKCJ_00992 3.8e-113 mhqD S Carboxylesterase
HGCOOKCJ_00993 4.8e-108 yodC C nitroreductase
HGCOOKCJ_00994 1.7e-57 yodB K transcriptional
HGCOOKCJ_00995 3.8e-66 yodA S tautomerase
HGCOOKCJ_00996 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
HGCOOKCJ_00997 3.4e-09
HGCOOKCJ_00998 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
HGCOOKCJ_00999 3.5e-163 rarD S -transporter
HGCOOKCJ_01000 1.5e-43
HGCOOKCJ_01001 2.2e-60 yojF S Protein of unknown function (DUF1806)
HGCOOKCJ_01002 2.1e-125 yojG S deacetylase
HGCOOKCJ_01003 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HGCOOKCJ_01004 4.2e-245 norM V Multidrug efflux pump
HGCOOKCJ_01006 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HGCOOKCJ_01007 1.8e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HGCOOKCJ_01008 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HGCOOKCJ_01009 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HGCOOKCJ_01010 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
HGCOOKCJ_01011 0.0 yojO P Von Willebrand factor
HGCOOKCJ_01012 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HGCOOKCJ_01013 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HGCOOKCJ_01014 5.1e-168 yocS S -transporter
HGCOOKCJ_01015 3.4e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HGCOOKCJ_01016 5.4e-166 sodA 1.15.1.1 P Superoxide dismutase
HGCOOKCJ_01017 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HGCOOKCJ_01018 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HGCOOKCJ_01019 2.7e-31 yozC
HGCOOKCJ_01020 4.2e-56 yozO S Bacterial PH domain
HGCOOKCJ_01021 1.9e-36 yocN
HGCOOKCJ_01022 1.1e-40 yozN
HGCOOKCJ_01023 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
HGCOOKCJ_01024 6.6e-34
HGCOOKCJ_01025 6.4e-54 yocL
HGCOOKCJ_01026 3.3e-83 dksA T general stress protein
HGCOOKCJ_01027 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HGCOOKCJ_01028 0.0 recQ 3.6.4.12 L DNA helicase
HGCOOKCJ_01029 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
HGCOOKCJ_01030 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGCOOKCJ_01031 3.2e-198 desK 2.7.13.3 T Histidine kinase
HGCOOKCJ_01032 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HGCOOKCJ_01033 6.9e-189 yocD 3.4.17.13 V peptidase S66
HGCOOKCJ_01034 1.9e-94 yocC
HGCOOKCJ_01035 2.2e-145
HGCOOKCJ_01036 1.5e-92 yozB S membrane
HGCOOKCJ_01037 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HGCOOKCJ_01038 1e-51 czrA K transcriptional
HGCOOKCJ_01039 2.5e-95 yobW
HGCOOKCJ_01040 9e-178 yobV K WYL domain
HGCOOKCJ_01041 1.5e-88 yobU K Bacterial transcription activator, effector binding domain
HGCOOKCJ_01042 4.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HGCOOKCJ_01043 3e-99 yobS K Transcriptional regulator
HGCOOKCJ_01044 2.5e-143 yobR 2.3.1.1 J FR47-like protein
HGCOOKCJ_01045 1e-136 yobQ K helix_turn_helix, arabinose operon control protein
HGCOOKCJ_01046 9.9e-55 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HGCOOKCJ_01047 0.0 yobO M Pectate lyase superfamily protein
HGCOOKCJ_01048 9.5e-280 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
HGCOOKCJ_01049 7.9e-105 yokH G SMI1 / KNR4 family
HGCOOKCJ_01050 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HGCOOKCJ_01051 3e-86 S SMI1-KNR4 cell-wall
HGCOOKCJ_01052 2.7e-157 yobJ
HGCOOKCJ_01053 0.0 K Psort location Cytoplasmic, score
HGCOOKCJ_01054 1.2e-49
HGCOOKCJ_01055 2.6e-38 S YolD-like protein
HGCOOKCJ_01056 1.4e-59 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HGCOOKCJ_01057 1.2e-123 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HGCOOKCJ_01059 1.7e-207 S aspartate phosphatase
HGCOOKCJ_01064 1.8e-178 yobF
HGCOOKCJ_01065 6.6e-127 yoqW S Belongs to the SOS response-associated peptidase family
HGCOOKCJ_01066 1.6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
HGCOOKCJ_01068 5.7e-58 K Helix-turn-helix
HGCOOKCJ_01069 1.4e-37 S TM2 domain
HGCOOKCJ_01070 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
HGCOOKCJ_01071 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
HGCOOKCJ_01075 2.3e-170 bla 3.5.2.6 V beta-lactamase
HGCOOKCJ_01076 1.1e-118 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HGCOOKCJ_01077 3.7e-78 yoaW
HGCOOKCJ_01078 6e-160 yijE EG EamA-like transporter family
HGCOOKCJ_01079 8.6e-159 yoaU K LysR substrate binding domain
HGCOOKCJ_01080 1.1e-149 yoaT S Protein of unknown function (DUF817)
HGCOOKCJ_01081 4.2e-37 yozG K Transcriptional regulator
HGCOOKCJ_01082 4.3e-75 yoaS S Protein of unknown function (DUF2975)
HGCOOKCJ_01083 2.4e-172 yoaR V vancomycin resistance protein
HGCOOKCJ_01084 4.1e-89
HGCOOKCJ_01085 1.2e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
HGCOOKCJ_01086 1.9e-146 yoaP 3.1.3.18 K YoaP-like
HGCOOKCJ_01088 3.8e-234 oxdC 4.1.1.2 G Oxalate decarboxylase
HGCOOKCJ_01090 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
HGCOOKCJ_01091 2.5e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
HGCOOKCJ_01092 2.3e-111 yoaK S Membrane
HGCOOKCJ_01093 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
HGCOOKCJ_01094 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HGCOOKCJ_01095 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
HGCOOKCJ_01096 1.5e-38 S Protein of unknown function (DUF4025)
HGCOOKCJ_01097 7e-14
HGCOOKCJ_01098 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
HGCOOKCJ_01099 1.9e-33 yoaF
HGCOOKCJ_01100 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HGCOOKCJ_01101 1.7e-190 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGCOOKCJ_01102 1e-284 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HGCOOKCJ_01103 6.2e-235 yoaB EGP Major facilitator Superfamily
HGCOOKCJ_01104 7.5e-97 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HGCOOKCJ_01105 3.1e-144 yoxB
HGCOOKCJ_01106 3e-42 yoxC S Bacterial protein of unknown function (DUF948)
HGCOOKCJ_01107 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HGCOOKCJ_01108 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HGCOOKCJ_01109 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HGCOOKCJ_01110 4.1e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HGCOOKCJ_01111 7.8e-155 gltC K Transcriptional regulator
HGCOOKCJ_01112 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HGCOOKCJ_01113 2.7e-293 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HGCOOKCJ_01114 5e-187 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HGCOOKCJ_01115 2.5e-158 gltR1 K Transcriptional regulator
HGCOOKCJ_01116 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HGCOOKCJ_01117 3e-34 yoeD G Helix-turn-helix domain
HGCOOKCJ_01118 2.2e-96 L Integrase
HGCOOKCJ_01120 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
HGCOOKCJ_01121 2.3e-246 yoeA V MATE efflux family protein
HGCOOKCJ_01122 6e-193 yoxA 5.1.3.3 G Aldose 1-epimerase
HGCOOKCJ_01123 4.3e-275 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HGCOOKCJ_01124 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGCOOKCJ_01125 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGCOOKCJ_01126 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGCOOKCJ_01127 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGCOOKCJ_01128 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
HGCOOKCJ_01129 2.8e-64 yngL S Protein of unknown function (DUF1360)
HGCOOKCJ_01130 1.3e-306 yngK T Glycosyl hydrolase-like 10
HGCOOKCJ_01131 1.8e-31 S Family of unknown function (DUF5367)
HGCOOKCJ_01132 4.4e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HGCOOKCJ_01133 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HGCOOKCJ_01134 3e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HGCOOKCJ_01135 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HGCOOKCJ_01136 8e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HGCOOKCJ_01137 2.2e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HGCOOKCJ_01138 6.3e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HGCOOKCJ_01139 1.9e-233 nrnB S phosphohydrolase (DHH superfamily)
HGCOOKCJ_01140 5.5e-104 yngC S membrane-associated protein
HGCOOKCJ_01141 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HGCOOKCJ_01142 2.4e-80 yngA S membrane
HGCOOKCJ_01143 4.4e-299 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HGCOOKCJ_01144 3.7e-251 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
HGCOOKCJ_01146 2.4e-297 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
HGCOOKCJ_01147 8.2e-252 agcS E Sodium alanine symporter
HGCOOKCJ_01148 1.3e-57 ynfC
HGCOOKCJ_01149 2.3e-12
HGCOOKCJ_01150 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HGCOOKCJ_01151 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HGCOOKCJ_01152 6.6e-69 yccU S CoA-binding protein
HGCOOKCJ_01153 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HGCOOKCJ_01154 4.1e-49 yneR S Belongs to the HesB IscA family
HGCOOKCJ_01155 1.3e-53 yneQ
HGCOOKCJ_01156 1.2e-73 yneP S Thioesterase-like superfamily
HGCOOKCJ_01157 3.9e-35 tlp S Belongs to the Tlp family
HGCOOKCJ_01158 3.1e-08 sspN S Small acid-soluble spore protein N family
HGCOOKCJ_01160 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HGCOOKCJ_01161 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HGCOOKCJ_01162 2.2e-14 sspO S Belongs to the SspO family
HGCOOKCJ_01163 3.9e-19 sspP S Belongs to the SspP family
HGCOOKCJ_01164 4.1e-65 hspX O Spore coat protein
HGCOOKCJ_01165 4.2e-74 yneK S Protein of unknown function (DUF2621)
HGCOOKCJ_01166 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HGCOOKCJ_01167 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HGCOOKCJ_01168 7.1e-127 ccdA O cytochrome c biogenesis protein
HGCOOKCJ_01169 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
HGCOOKCJ_01170 1.8e-28 yneF S UPF0154 protein
HGCOOKCJ_01171 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
HGCOOKCJ_01172 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HGCOOKCJ_01173 1.3e-32 ynzC S UPF0291 protein
HGCOOKCJ_01174 9.2e-113 yneB L resolvase
HGCOOKCJ_01175 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HGCOOKCJ_01176 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HGCOOKCJ_01178 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HGCOOKCJ_01179 5.8e-74 yndM S Protein of unknown function (DUF2512)
HGCOOKCJ_01180 8.6e-139 yndL S Replication protein
HGCOOKCJ_01182 0.0 yndJ S YndJ-like protein
HGCOOKCJ_01183 2.6e-117 yndH S Domain of unknown function (DUF4166)
HGCOOKCJ_01184 7.7e-154 yndG S DoxX-like family
HGCOOKCJ_01185 4.2e-220 gerLC S Spore germination protein
HGCOOKCJ_01186 4.5e-197 gerAB U Spore germination
HGCOOKCJ_01187 5.7e-286 gerAA EG Spore germination protein
HGCOOKCJ_01190 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HGCOOKCJ_01191 1.8e-71
HGCOOKCJ_01192 7.9e-25 tatA U protein secretion
HGCOOKCJ_01195 1.3e-134 S Domain of unknown function, YrpD
HGCOOKCJ_01197 1.2e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HGCOOKCJ_01200 5.2e-15
HGCOOKCJ_01201 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HGCOOKCJ_01202 6.3e-84 yncE S Protein of unknown function (DUF2691)
HGCOOKCJ_01203 2.7e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HGCOOKCJ_01204 3.5e-247 iolT EGP Major facilitator Superfamily
HGCOOKCJ_01205 1.4e-113 yokF 3.1.31.1 L RNA catabolic process
HGCOOKCJ_01206 6e-293 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
HGCOOKCJ_01207 4e-264 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HGCOOKCJ_01208 1e-215 xylR GK ROK family
HGCOOKCJ_01209 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HGCOOKCJ_01210 2.7e-255 xynT G MFS/sugar transport protein
HGCOOKCJ_01211 1.1e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
HGCOOKCJ_01214 6.4e-60 ynaF
HGCOOKCJ_01215 1.9e-123 ynaE S Domain of unknown function (DUF3885)
HGCOOKCJ_01216 2e-99 ynaD J Acetyltransferase (GNAT) domain
HGCOOKCJ_01217 4.9e-145 ynaC
HGCOOKCJ_01218 6.8e-80 G regulation of fungal-type cell wall biogenesis
HGCOOKCJ_01219 5.8e-39
HGCOOKCJ_01220 2.5e-32
HGCOOKCJ_01221 5e-10
HGCOOKCJ_01222 7e-261 glnA 6.3.1.2 E glutamine synthetase
HGCOOKCJ_01223 1.1e-68 glnR K transcriptional
HGCOOKCJ_01224 3.3e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HGCOOKCJ_01225 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HGCOOKCJ_01226 1.7e-176 spoVK O stage V sporulation protein K
HGCOOKCJ_01227 8e-116 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HGCOOKCJ_01228 2e-109 ymaB
HGCOOKCJ_01229 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGCOOKCJ_01230 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGCOOKCJ_01231 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HGCOOKCJ_01232 4.5e-22 ymzA
HGCOOKCJ_01233 6.3e-23
HGCOOKCJ_01234 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HGCOOKCJ_01235 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HGCOOKCJ_01236 2.1e-46 ymaF S YmaF family
HGCOOKCJ_01238 4.9e-51 ebrA P Small Multidrug Resistance protein
HGCOOKCJ_01239 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
HGCOOKCJ_01240 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
HGCOOKCJ_01241 2.1e-126 ymaC S Replication protein
HGCOOKCJ_01242 4.6e-252 aprX O Belongs to the peptidase S8 family
HGCOOKCJ_01243 6.6e-164 ymaE S Metallo-beta-lactamase superfamily
HGCOOKCJ_01244 1.2e-61 ymzB
HGCOOKCJ_01245 2.5e-233 cypA C Cytochrome P450
HGCOOKCJ_01246 0.0 pks13 HQ Beta-ketoacyl synthase
HGCOOKCJ_01247 0.0 dhbF IQ polyketide synthase
HGCOOKCJ_01248 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
HGCOOKCJ_01249 0.0 pfaA Q Polyketide synthase of type I
HGCOOKCJ_01250 0.0 rhiB IQ polyketide synthase
HGCOOKCJ_01251 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HGCOOKCJ_01252 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
HGCOOKCJ_01253 1.3e-245 pksG 2.3.3.10 I synthase
HGCOOKCJ_01254 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HGCOOKCJ_01255 1.4e-37 acpK IQ Phosphopantetheine attachment site
HGCOOKCJ_01256 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HGCOOKCJ_01257 2.4e-186 pksD Q Acyl transferase domain
HGCOOKCJ_01258 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HGCOOKCJ_01259 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
HGCOOKCJ_01260 4.4e-109 pksA K Transcriptional regulator
HGCOOKCJ_01261 1.2e-97 ymcC S Membrane
HGCOOKCJ_01263 2.3e-70 S Regulatory protein YrvL
HGCOOKCJ_01264 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HGCOOKCJ_01265 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HGCOOKCJ_01266 2.2e-88 cotE S Spore coat protein
HGCOOKCJ_01267 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HGCOOKCJ_01268 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HGCOOKCJ_01269 6.5e-218 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HGCOOKCJ_01270 2.7e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HGCOOKCJ_01271 1.2e-36 spoVS S Stage V sporulation protein S
HGCOOKCJ_01272 1.9e-152 ymdB S protein conserved in bacteria
HGCOOKCJ_01273 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
HGCOOKCJ_01274 1e-215 pbpX V Beta-lactamase
HGCOOKCJ_01275 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HGCOOKCJ_01276 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
HGCOOKCJ_01277 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HGCOOKCJ_01278 1.9e-124 ymfM S protein conserved in bacteria
HGCOOKCJ_01279 2.7e-143 ymfK S Protein of unknown function (DUF3388)
HGCOOKCJ_01280 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
HGCOOKCJ_01281 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HGCOOKCJ_01282 1.4e-242 ymfH S zinc protease
HGCOOKCJ_01283 2.9e-235 ymfF S Peptidase M16
HGCOOKCJ_01284 1.5e-206 ymfD EGP Major facilitator Superfamily
HGCOOKCJ_01285 1.4e-133 ymfC K Transcriptional regulator
HGCOOKCJ_01286 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HGCOOKCJ_01287 4.4e-32 S YlzJ-like protein
HGCOOKCJ_01288 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HGCOOKCJ_01289 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HGCOOKCJ_01290 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HGCOOKCJ_01291 5.9e-222 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HGCOOKCJ_01292 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HGCOOKCJ_01293 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HGCOOKCJ_01294 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HGCOOKCJ_01295 2.6e-42 ymxH S YlmC YmxH family
HGCOOKCJ_01296 4.4e-233 pepR S Belongs to the peptidase M16 family
HGCOOKCJ_01297 4.2e-183 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HGCOOKCJ_01298 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HGCOOKCJ_01299 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HGCOOKCJ_01300 6.1e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HGCOOKCJ_01301 1.3e-173 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HGCOOKCJ_01302 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HGCOOKCJ_01303 3e-44 ylxP S protein conserved in bacteria
HGCOOKCJ_01304 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HGCOOKCJ_01305 3.1e-47 ylxQ J ribosomal protein
HGCOOKCJ_01306 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
HGCOOKCJ_01307 1.1e-203 nusA K Participates in both transcription termination and antitermination
HGCOOKCJ_01308 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
HGCOOKCJ_01309 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HGCOOKCJ_01310 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HGCOOKCJ_01311 7.7e-233 rasP M zinc metalloprotease
HGCOOKCJ_01312 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HGCOOKCJ_01313 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
HGCOOKCJ_01314 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HGCOOKCJ_01315 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HGCOOKCJ_01316 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HGCOOKCJ_01317 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HGCOOKCJ_01318 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HGCOOKCJ_01319 4.3e-78 ylxL
HGCOOKCJ_01320 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGCOOKCJ_01321 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HGCOOKCJ_01322 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HGCOOKCJ_01323 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
HGCOOKCJ_01324 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HGCOOKCJ_01325 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HGCOOKCJ_01326 4.8e-157 flhG D Belongs to the ParA family
HGCOOKCJ_01327 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
HGCOOKCJ_01328 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HGCOOKCJ_01329 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HGCOOKCJ_01330 8.1e-132 fliR N Flagellar biosynthetic protein FliR
HGCOOKCJ_01331 2.2e-36 fliQ N Role in flagellar biosynthesis
HGCOOKCJ_01332 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
HGCOOKCJ_01333 9.3e-97 fliZ N Flagellar biosynthesis protein, FliO
HGCOOKCJ_01334 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
HGCOOKCJ_01335 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HGCOOKCJ_01336 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HGCOOKCJ_01337 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
HGCOOKCJ_01338 8.2e-140 flgG N Flagellar basal body rod
HGCOOKCJ_01339 1.7e-72 flgD N Flagellar basal body rod modification protein
HGCOOKCJ_01340 1.2e-221 fliK N Flagellar hook-length control protein
HGCOOKCJ_01341 7.7e-37 ylxF S MgtE intracellular N domain
HGCOOKCJ_01342 1.5e-69 fliJ N Flagellar biosynthesis chaperone
HGCOOKCJ_01343 2.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HGCOOKCJ_01344 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HGCOOKCJ_01345 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HGCOOKCJ_01346 2.4e-255 fliF N The M ring may be actively involved in energy transduction
HGCOOKCJ_01347 1.9e-31 fliE N Flagellar hook-basal body
HGCOOKCJ_01348 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
HGCOOKCJ_01349 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HGCOOKCJ_01350 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HGCOOKCJ_01351 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HGCOOKCJ_01352 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HGCOOKCJ_01353 2.5e-169 xerC L tyrosine recombinase XerC
HGCOOKCJ_01354 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HGCOOKCJ_01355 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HGCOOKCJ_01356 1.7e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HGCOOKCJ_01357 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HGCOOKCJ_01358 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HGCOOKCJ_01359 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HGCOOKCJ_01360 8.5e-291 ylqG
HGCOOKCJ_01361 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HGCOOKCJ_01362 4.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HGCOOKCJ_01363 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HGCOOKCJ_01364 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HGCOOKCJ_01365 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HGCOOKCJ_01366 1.3e-61 ylqD S YlqD protein
HGCOOKCJ_01367 1.2e-36 ylqC S Belongs to the UPF0109 family
HGCOOKCJ_01368 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HGCOOKCJ_01369 6e-236 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HGCOOKCJ_01370 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HGCOOKCJ_01371 2.9e-87
HGCOOKCJ_01372 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HGCOOKCJ_01373 0.0 smc D Required for chromosome condensation and partitioning
HGCOOKCJ_01374 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HGCOOKCJ_01375 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HGCOOKCJ_01376 6.1e-129 IQ reductase
HGCOOKCJ_01377 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HGCOOKCJ_01378 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HGCOOKCJ_01379 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HGCOOKCJ_01380 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HGCOOKCJ_01381 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
HGCOOKCJ_01382 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
HGCOOKCJ_01383 2.7e-302 yloV S kinase related to dihydroxyacetone kinase
HGCOOKCJ_01384 5.5e-59 asp S protein conserved in bacteria
HGCOOKCJ_01385 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HGCOOKCJ_01386 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
HGCOOKCJ_01387 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HGCOOKCJ_01388 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HGCOOKCJ_01389 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HGCOOKCJ_01390 2.4e-141 stp 3.1.3.16 T phosphatase
HGCOOKCJ_01391 4.8e-207 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HGCOOKCJ_01392 2.9e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HGCOOKCJ_01393 3.8e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HGCOOKCJ_01394 6e-85 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HGCOOKCJ_01395 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HGCOOKCJ_01396 8.8e-226 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HGCOOKCJ_01397 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HGCOOKCJ_01398 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HGCOOKCJ_01399 1.5e-40 ylzA S Belongs to the UPF0296 family
HGCOOKCJ_01400 2.4e-156 yloC S stress-induced protein
HGCOOKCJ_01401 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HGCOOKCJ_01402 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HGCOOKCJ_01403 4.3e-83 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HGCOOKCJ_01404 2e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HGCOOKCJ_01405 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HGCOOKCJ_01406 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HGCOOKCJ_01407 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HGCOOKCJ_01408 1.1e-179 cysP P phosphate transporter
HGCOOKCJ_01409 3.5e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HGCOOKCJ_01411 2.9e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HGCOOKCJ_01412 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HGCOOKCJ_01413 2.9e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HGCOOKCJ_01414 4.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HGCOOKCJ_01415 0.0 carB 6.3.5.5 F Belongs to the CarB family
HGCOOKCJ_01416 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HGCOOKCJ_01417 1.7e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HGCOOKCJ_01418 1.4e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HGCOOKCJ_01419 9e-232 pyrP F Xanthine uracil
HGCOOKCJ_01420 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HGCOOKCJ_01421 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HGCOOKCJ_01422 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HGCOOKCJ_01423 1.3e-63 dksA T COG1734 DnaK suppressor protein
HGCOOKCJ_01424 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HGCOOKCJ_01425 2.6e-67 divIVA D Cell division initiation protein
HGCOOKCJ_01426 6.7e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HGCOOKCJ_01427 1.3e-39 yggT S membrane
HGCOOKCJ_01428 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HGCOOKCJ_01429 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HGCOOKCJ_01430 1.1e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HGCOOKCJ_01431 2.4e-37 ylmC S sporulation protein
HGCOOKCJ_01432 1.3e-256 argE 3.5.1.16 E Acetylornithine deacetylase
HGCOOKCJ_01433 1.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HGCOOKCJ_01434 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGCOOKCJ_01435 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGCOOKCJ_01436 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HGCOOKCJ_01437 0.0 bpr O COG1404 Subtilisin-like serine proteases
HGCOOKCJ_01438 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HGCOOKCJ_01439 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HGCOOKCJ_01440 6.2e-58 sbp S small basic protein
HGCOOKCJ_01441 1e-102 ylxX S protein conserved in bacteria
HGCOOKCJ_01442 2.4e-103 ylxW S protein conserved in bacteria
HGCOOKCJ_01443 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HGCOOKCJ_01444 5.3e-167 murB 1.3.1.98 M cell wall formation
HGCOOKCJ_01445 2.3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HGCOOKCJ_01446 5.7e-186 spoVE D Belongs to the SEDS family
HGCOOKCJ_01447 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HGCOOKCJ_01448 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HGCOOKCJ_01449 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HGCOOKCJ_01450 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HGCOOKCJ_01451 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HGCOOKCJ_01452 3.7e-44 ftsL D Essential cell division protein
HGCOOKCJ_01453 6.6e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HGCOOKCJ_01454 2.9e-78 mraZ K Belongs to the MraZ family
HGCOOKCJ_01455 2.9e-309 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HGCOOKCJ_01456 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HGCOOKCJ_01457 4e-89 ylbP K n-acetyltransferase
HGCOOKCJ_01458 6.8e-75 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HGCOOKCJ_01459 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HGCOOKCJ_01460 1.3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
HGCOOKCJ_01462 2.8e-235 ylbM S Belongs to the UPF0348 family
HGCOOKCJ_01463 6.8e-187 ylbL T Belongs to the peptidase S16 family
HGCOOKCJ_01464 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
HGCOOKCJ_01465 3.8e-221 ylbJ S Sporulation integral membrane protein YlbJ
HGCOOKCJ_01466 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HGCOOKCJ_01467 1.9e-98 rsmD 2.1.1.171 L Methyltransferase
HGCOOKCJ_01468 7.5e-39 ylbG S UPF0298 protein
HGCOOKCJ_01469 1.8e-75 ylbF S Belongs to the UPF0342 family
HGCOOKCJ_01470 6.7e-37 ylbE S YlbE-like protein
HGCOOKCJ_01471 4.1e-63 ylbD S Putative coat protein
HGCOOKCJ_01472 3e-201 ylbC S protein with SCP PR1 domains
HGCOOKCJ_01473 9.8e-74 ylbB T COG0517 FOG CBS domain
HGCOOKCJ_01474 7e-62 ylbA S YugN-like family
HGCOOKCJ_01475 3e-167 ctaG S cytochrome c oxidase
HGCOOKCJ_01476 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HGCOOKCJ_01477 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HGCOOKCJ_01478 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HGCOOKCJ_01479 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HGCOOKCJ_01480 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HGCOOKCJ_01481 2.6e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HGCOOKCJ_01482 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HGCOOKCJ_01483 4.5e-214 ftsW D Belongs to the SEDS family
HGCOOKCJ_01484 8.7e-44 ylaN S Belongs to the UPF0358 family
HGCOOKCJ_01485 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
HGCOOKCJ_01486 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HGCOOKCJ_01487 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HGCOOKCJ_01488 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HGCOOKCJ_01489 2.5e-32 ylaI S protein conserved in bacteria
HGCOOKCJ_01490 4.2e-47 ylaH S YlaH-like protein
HGCOOKCJ_01491 0.0 typA T GTP-binding protein TypA
HGCOOKCJ_01492 8.2e-22 S Family of unknown function (DUF5325)
HGCOOKCJ_01493 1.8e-38 ylaE
HGCOOKCJ_01494 1.2e-11 sigC S Putative zinc-finger
HGCOOKCJ_01495 2.7e-91 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
HGCOOKCJ_01496 2.7e-42 ylaB
HGCOOKCJ_01497 0.0 ylaA
HGCOOKCJ_01498 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HGCOOKCJ_01499 6.5e-173 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HGCOOKCJ_01500 6.9e-78 ykzC S Acetyltransferase (GNAT) family
HGCOOKCJ_01501 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
HGCOOKCJ_01502 7.1e-26 ykzI
HGCOOKCJ_01503 7.1e-118 yktB S Belongs to the UPF0637 family
HGCOOKCJ_01504 1.6e-42 yktA S Belongs to the UPF0223 family
HGCOOKCJ_01505 3.5e-277 speA 4.1.1.19 E Arginine
HGCOOKCJ_01506 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HGCOOKCJ_01507 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HGCOOKCJ_01508 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HGCOOKCJ_01509 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HGCOOKCJ_01510 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HGCOOKCJ_01511 2e-115 recN L Putative cell-wall binding lipoprotein
HGCOOKCJ_01513 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HGCOOKCJ_01514 1.4e-147 ykrA S hydrolases of the HAD superfamily
HGCOOKCJ_01515 8.2e-31 ykzG S Belongs to the UPF0356 family
HGCOOKCJ_01516 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HGCOOKCJ_01517 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HGCOOKCJ_01518 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
HGCOOKCJ_01519 1.6e-162 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HGCOOKCJ_01520 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HGCOOKCJ_01521 1.5e-43 abrB K of stationary sporulation gene expression
HGCOOKCJ_01522 7.7e-183 mreB D Rod-share determining protein MreBH
HGCOOKCJ_01523 1.1e-12 S Uncharacterized protein YkpC
HGCOOKCJ_01524 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HGCOOKCJ_01525 1.5e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HGCOOKCJ_01526 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HGCOOKCJ_01527 8.1e-39 ykoA
HGCOOKCJ_01528 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HGCOOKCJ_01529 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HGCOOKCJ_01530 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HGCOOKCJ_01531 3.1e-136 fruR K Transcriptional regulator
HGCOOKCJ_01532 2.1e-211 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
HGCOOKCJ_01533 2.5e-124 macB V ABC transporter, ATP-binding protein
HGCOOKCJ_01534 3e-159 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HGCOOKCJ_01535 1e-117 yknW S Yip1 domain
HGCOOKCJ_01536 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
HGCOOKCJ_01537 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
HGCOOKCJ_01538 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HGCOOKCJ_01539 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HGCOOKCJ_01540 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HGCOOKCJ_01541 8.1e-246 moeA 2.10.1.1 H molybdopterin
HGCOOKCJ_01542 5.3e-192 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HGCOOKCJ_01543 3.9e-110 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HGCOOKCJ_01544 2.9e-147 yknT
HGCOOKCJ_01545 5.8e-95 rok K Repressor of ComK
HGCOOKCJ_01546 4.4e-82 ykuV CO thiol-disulfide
HGCOOKCJ_01547 3.9e-101 ykuU O Alkyl hydroperoxide reductase
HGCOOKCJ_01548 8.8e-142 ykuT M Mechanosensitive ion channel
HGCOOKCJ_01549 9e-37 ykuS S Belongs to the UPF0180 family
HGCOOKCJ_01550 5.8e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HGCOOKCJ_01551 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HGCOOKCJ_01552 3.2e-80 fld C Flavodoxin
HGCOOKCJ_01553 3.2e-177 ykuO
HGCOOKCJ_01554 5.7e-88 fld C Flavodoxin domain
HGCOOKCJ_01555 3.5e-168 ccpC K Transcriptional regulator
HGCOOKCJ_01556 1.6e-76 ykuL S CBS domain
HGCOOKCJ_01557 3.9e-27 ykzF S Antirepressor AbbA
HGCOOKCJ_01558 4.4e-94 ykuK S Ribonuclease H-like
HGCOOKCJ_01559 3.9e-37 ykuJ S protein conserved in bacteria
HGCOOKCJ_01560 5.2e-234 ykuI T Diguanylate phosphodiesterase
HGCOOKCJ_01562 1.7e-93 M Peptidoglycan-binding domain 1 protein
HGCOOKCJ_01563 0.0 3.2.1.132 M Putative peptidoglycan binding domain
HGCOOKCJ_01564 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGCOOKCJ_01565 9.4e-166 ykuE S Metallophosphoesterase
HGCOOKCJ_01566 4.6e-88 ykuD S protein conserved in bacteria
HGCOOKCJ_01567 1.6e-238 ykuC EGP Major facilitator Superfamily
HGCOOKCJ_01568 1.7e-84 ykyB S YkyB-like protein
HGCOOKCJ_01569 1.6e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
HGCOOKCJ_01570 2.2e-15
HGCOOKCJ_01571 8e-224 patA 2.6.1.1 E Aminotransferase
HGCOOKCJ_01572 0.0 pilS 2.7.13.3 T Histidine kinase
HGCOOKCJ_01573 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
HGCOOKCJ_01574 8e-124 ykwD J protein with SCP PR1 domains
HGCOOKCJ_01575 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HGCOOKCJ_01576 2e-264 mcpC NT chemotaxis protein
HGCOOKCJ_01577 1.2e-131 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGCOOKCJ_01578 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
HGCOOKCJ_01579 7.2e-39 splA S Transcriptional regulator
HGCOOKCJ_01580 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HGCOOKCJ_01581 2.1e-39 ptsH G phosphocarrier protein HPr
HGCOOKCJ_01582 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HGCOOKCJ_01583 4.5e-128 glcT K antiterminator
HGCOOKCJ_01585 9.8e-180 ykvZ 5.1.1.1 K Transcriptional regulator
HGCOOKCJ_01587 8.7e-209 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HGCOOKCJ_01588 3.8e-09
HGCOOKCJ_01589 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HGCOOKCJ_01590 4.9e-90 stoA CO thiol-disulfide
HGCOOKCJ_01591 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HGCOOKCJ_01592 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
HGCOOKCJ_01593 2.8e-28
HGCOOKCJ_01594 6e-25 ykvS S protein conserved in bacteria
HGCOOKCJ_01595 5.6e-46 ykvR S Protein of unknown function (DUF3219)
HGCOOKCJ_01596 8.5e-133 G Glycosyl hydrolases family 18
HGCOOKCJ_01597 1.2e-35 3.5.1.104 M LysM domain
HGCOOKCJ_01598 4e-217 ykvP 3.5.1.28 M Glycosyl transferases group 1
HGCOOKCJ_01599 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
HGCOOKCJ_01600 2e-61 ykvN K Transcriptional regulator
HGCOOKCJ_01601 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HGCOOKCJ_01602 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HGCOOKCJ_01603 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
HGCOOKCJ_01604 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HGCOOKCJ_01605 8.7e-182 ykvI S membrane
HGCOOKCJ_01606 0.0 clpE O Belongs to the ClpA ClpB family
HGCOOKCJ_01607 2.7e-138 motA N flagellar motor
HGCOOKCJ_01608 2.5e-125 motB N Flagellar motor protein
HGCOOKCJ_01609 1.3e-75 ykvE K transcriptional
HGCOOKCJ_01610 2.5e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
HGCOOKCJ_01611 1.4e-64 eag
HGCOOKCJ_01612 6.4e-09 S Spo0E like sporulation regulatory protein
HGCOOKCJ_01613 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
HGCOOKCJ_01614 1.3e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HGCOOKCJ_01615 7.2e-115 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HGCOOKCJ_01616 7.5e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HGCOOKCJ_01617 4.1e-231 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HGCOOKCJ_01618 8e-232 mtnE 2.6.1.83 E Aminotransferase
HGCOOKCJ_01619 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HGCOOKCJ_01620 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HGCOOKCJ_01621 3.3e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HGCOOKCJ_01623 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HGCOOKCJ_01624 0.0 kinE 2.7.13.3 T Histidine kinase
HGCOOKCJ_01625 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HGCOOKCJ_01626 4.5e-22 ykzE
HGCOOKCJ_01627 1.2e-10 ydfR S Protein of unknown function (DUF421)
HGCOOKCJ_01628 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
HGCOOKCJ_01629 7e-156 htpX O Belongs to the peptidase M48B family
HGCOOKCJ_01630 1.5e-124 ykrK S Domain of unknown function (DUF1836)
HGCOOKCJ_01631 1.9e-26 sspD S small acid-soluble spore protein
HGCOOKCJ_01632 8.2e-117 rsgI S Anti-sigma factor N-terminus
HGCOOKCJ_01633 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGCOOKCJ_01634 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HGCOOKCJ_01635 1.4e-116 ykoX S membrane-associated protein
HGCOOKCJ_01636 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
HGCOOKCJ_01637 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HGCOOKCJ_01638 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HGCOOKCJ_01639 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HGCOOKCJ_01640 0.0 ykoS
HGCOOKCJ_01641 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
HGCOOKCJ_01642 3.7e-99 ykoP G polysaccharide deacetylase
HGCOOKCJ_01643 2.3e-220 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HGCOOKCJ_01644 1.3e-81 mhqR K transcriptional
HGCOOKCJ_01645 6.9e-26 ykoL
HGCOOKCJ_01646 5.9e-18
HGCOOKCJ_01647 1.4e-53 tnrA K transcriptional
HGCOOKCJ_01648 2.2e-222 mgtE P Acts as a magnesium transporter
HGCOOKCJ_01651 4.4e-86 ykoJ S Peptidase propeptide and YPEB domain
HGCOOKCJ_01652 1.1e-113 ykoI S Peptidase propeptide and YPEB domain
HGCOOKCJ_01653 9.4e-245 ykoH 2.7.13.3 T Histidine kinase
HGCOOKCJ_01654 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGCOOKCJ_01655 7.9e-111 ykoF S YKOF-related Family
HGCOOKCJ_01656 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
HGCOOKCJ_01657 4.6e-311 P ABC transporter, ATP-binding protein
HGCOOKCJ_01658 1.8e-136 ykoC P Cobalt transport protein
HGCOOKCJ_01659 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HGCOOKCJ_01660 1.7e-176 isp O Belongs to the peptidase S8 family
HGCOOKCJ_01661 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HGCOOKCJ_01662 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
HGCOOKCJ_01664 8.4e-72 ohrB O Organic hydroperoxide resistance protein
HGCOOKCJ_01665 3.9e-75 ohrR K COG1846 Transcriptional regulators
HGCOOKCJ_01666 1.3e-70 ohrA O Organic hydroperoxide resistance protein
HGCOOKCJ_01667 2.5e-228 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HGCOOKCJ_01668 1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HGCOOKCJ_01669 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HGCOOKCJ_01670 1.1e-50 ykkD P Multidrug resistance protein
HGCOOKCJ_01671 3.5e-55 ykkC P Multidrug resistance protein
HGCOOKCJ_01672 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HGCOOKCJ_01673 1e-98 ykkA S Protein of unknown function (DUF664)
HGCOOKCJ_01674 5.4e-130 ykjA S Protein of unknown function (DUF421)
HGCOOKCJ_01675 1e-07
HGCOOKCJ_01676 1e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HGCOOKCJ_01677 1.5e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HGCOOKCJ_01678 5.3e-161 ykgA E Amidinotransferase
HGCOOKCJ_01679 7.4e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
HGCOOKCJ_01680 7.7e-188 ykfD E Belongs to the ABC transporter superfamily
HGCOOKCJ_01681 5.3e-172 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HGCOOKCJ_01682 3.2e-203 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HGCOOKCJ_01683 8.1e-179 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HGCOOKCJ_01685 0.0 dppE E ABC transporter substrate-binding protein
HGCOOKCJ_01686 3.4e-191 dppD P Belongs to the ABC transporter superfamily
HGCOOKCJ_01687 3.9e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGCOOKCJ_01688 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGCOOKCJ_01689 7.9e-154 dppA E D-aminopeptidase
HGCOOKCJ_01690 1e-137 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
HGCOOKCJ_01691 8.5e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HGCOOKCJ_01693 1.3e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HGCOOKCJ_01694 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HGCOOKCJ_01696 7.2e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HGCOOKCJ_01697 9.4e-242 steT E amino acid
HGCOOKCJ_01698 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HGCOOKCJ_01699 5.8e-175 pit P phosphate transporter
HGCOOKCJ_01700 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HGCOOKCJ_01701 6.7e-23 spoIISB S Stage II sporulation protein SB
HGCOOKCJ_01702 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HGCOOKCJ_01703 9.3e-40 xhlB S SPP1 phage holin
HGCOOKCJ_01704 2.8e-39 xhlA S Haemolysin XhlA
HGCOOKCJ_01705 1.2e-154 xepA
HGCOOKCJ_01706 1.7e-23 xkdX
HGCOOKCJ_01707 2.6e-55 xkdW S XkdW protein
HGCOOKCJ_01708 0.0
HGCOOKCJ_01709 6.7e-41
HGCOOKCJ_01710 4e-104 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HGCOOKCJ_01711 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HGCOOKCJ_01712 9.6e-71 xkdS S Protein of unknown function (DUF2634)
HGCOOKCJ_01713 2.1e-39 xkdR S Protein of unknown function (DUF2577)
HGCOOKCJ_01714 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
HGCOOKCJ_01715 3.7e-122 xkdP S Lysin motif
HGCOOKCJ_01716 0.0 xkdO L Transglycosylase SLT domain
HGCOOKCJ_01717 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
HGCOOKCJ_01718 6.1e-76 xkdM S Phage tail tube protein
HGCOOKCJ_01719 2.5e-256 xkdK S Phage tail sheath C-terminal domain
HGCOOKCJ_01720 1.9e-77 xkdJ
HGCOOKCJ_01721 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
HGCOOKCJ_01722 8.7e-65 yqbH S Domain of unknown function (DUF3599)
HGCOOKCJ_01723 5.5e-65 yqbG S Protein of unknown function (DUF3199)
HGCOOKCJ_01724 5.8e-169 xkdG S Phage capsid family
HGCOOKCJ_01725 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HGCOOKCJ_01726 5.4e-286 yqbA S portal protein
HGCOOKCJ_01727 9.6e-255 xtmB S phage terminase, large subunit
HGCOOKCJ_01728 4.8e-140 xtmA L phage terminase small subunit
HGCOOKCJ_01729 4.4e-86 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HGCOOKCJ_01730 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
HGCOOKCJ_01733 6.4e-119 xkdC L Bacterial dnaA protein
HGCOOKCJ_01734 5.9e-157 xkdB K sequence-specific DNA binding
HGCOOKCJ_01736 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
HGCOOKCJ_01737 1.6e-111 xkdA E IrrE N-terminal-like domain
HGCOOKCJ_01738 4.4e-160 ydbD P Catalase
HGCOOKCJ_01739 4.2e-112 yjqB S Pfam:DUF867
HGCOOKCJ_01740 2.1e-61 yjqA S Bacterial PH domain
HGCOOKCJ_01741 9.1e-170 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
HGCOOKCJ_01742 6.3e-41 S YCII-related domain
HGCOOKCJ_01744 2.1e-213 S response regulator aspartate phosphatase
HGCOOKCJ_01745 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
HGCOOKCJ_01746 3.3e-80 yjoA S DinB family
HGCOOKCJ_01747 4.3e-130 MA20_18170 S membrane transporter protein
HGCOOKCJ_01748 2e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HGCOOKCJ_01749 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HGCOOKCJ_01750 2.3e-184 exuR K transcriptional
HGCOOKCJ_01751 3.7e-227 exuT G Sugar (and other) transporter
HGCOOKCJ_01752 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HGCOOKCJ_01753 4.7e-215 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HGCOOKCJ_01754 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HGCOOKCJ_01755 3e-195 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HGCOOKCJ_01756 5.8e-250 yjmB G symporter YjmB
HGCOOKCJ_01757 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
HGCOOKCJ_01758 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
HGCOOKCJ_01759 7.1e-66 yjlC S Protein of unknown function (DUF1641)
HGCOOKCJ_01760 2.8e-93 yjlB S Cupin domain
HGCOOKCJ_01761 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
HGCOOKCJ_01762 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
HGCOOKCJ_01763 1.9e-122 ybbM S transport system, permease component
HGCOOKCJ_01764 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HGCOOKCJ_01765 8.2e-30
HGCOOKCJ_01766 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HGCOOKCJ_01767 3.8e-226 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HGCOOKCJ_01769 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HGCOOKCJ_01770 8.7e-07 S Domain of unknown function (DUF4352)
HGCOOKCJ_01771 4.3e-95 yjgD S Protein of unknown function (DUF1641)
HGCOOKCJ_01772 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HGCOOKCJ_01773 8.9e-104 yjgB S Domain of unknown function (DUF4309)
HGCOOKCJ_01774 1.2e-45 T PhoQ Sensor
HGCOOKCJ_01775 1.6e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
HGCOOKCJ_01776 3.6e-21 yjfB S Putative motility protein
HGCOOKCJ_01777 5.5e-83 S Protein of unknown function (DUF2690)
HGCOOKCJ_01778 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
HGCOOKCJ_01780 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HGCOOKCJ_01781 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
HGCOOKCJ_01782 4.2e-29 S Domain of unknown function (DUF4177)
HGCOOKCJ_01783 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HGCOOKCJ_01785 2.5e-94 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
HGCOOKCJ_01786 4.8e-51 yjdF S Protein of unknown function (DUF2992)
HGCOOKCJ_01787 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
HGCOOKCJ_01788 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HGCOOKCJ_01789 5.6e-65 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HGCOOKCJ_01790 1.3e-264 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HGCOOKCJ_01792 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
HGCOOKCJ_01793 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
HGCOOKCJ_01794 1.1e-92 yqaS L DNA packaging
HGCOOKCJ_01795 4.1e-49 S YjcQ protein
HGCOOKCJ_01796 1.6e-72 yjcP
HGCOOKCJ_01797 8.5e-81 L Transposase
HGCOOKCJ_01800 2.6e-44 yjcN
HGCOOKCJ_01801 2.1e-190 S Putative amidase domain
HGCOOKCJ_01804 1.1e-212 yjcL S Protein of unknown function (DUF819)
HGCOOKCJ_01805 3.7e-99 rimJ 2.3.1.128 J Alanine acetyltransferase
HGCOOKCJ_01806 2.9e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HGCOOKCJ_01807 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HGCOOKCJ_01808 1.8e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
HGCOOKCJ_01809 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HGCOOKCJ_01810 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGCOOKCJ_01811 1.7e-38
HGCOOKCJ_01812 0.0 yjcD 3.6.4.12 L DNA helicase
HGCOOKCJ_01813 2.9e-38 spoVIF S Stage VI sporulation protein F
HGCOOKCJ_01816 8.7e-57 yjcA S Protein of unknown function (DUF1360)
HGCOOKCJ_01817 2.3e-55 cotV S Spore Coat Protein X and V domain
HGCOOKCJ_01818 3e-32 cotW
HGCOOKCJ_01819 6.4e-77 cotX S Spore Coat Protein X and V domain
HGCOOKCJ_01820 3.4e-96 cotY S Spore coat protein Z
HGCOOKCJ_01821 5.2e-83 cotZ S Spore coat protein
HGCOOKCJ_01822 5.9e-54 yjbX S Spore coat protein
HGCOOKCJ_01823 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HGCOOKCJ_01824 5.3e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HGCOOKCJ_01825 6e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HGCOOKCJ_01826 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HGCOOKCJ_01827 3e-30 thiS H thiamine diphosphate biosynthetic process
HGCOOKCJ_01828 7.2e-219 thiO 1.4.3.19 E Glycine oxidase
HGCOOKCJ_01829 3.8e-108 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HGCOOKCJ_01830 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HGCOOKCJ_01831 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HGCOOKCJ_01832 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HGCOOKCJ_01833 9.5e-161 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HGCOOKCJ_01834 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HGCOOKCJ_01835 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
HGCOOKCJ_01836 7.1e-62 yjbL S Belongs to the UPF0738 family
HGCOOKCJ_01837 2.4e-101 yjbK S protein conserved in bacteria
HGCOOKCJ_01838 1.5e-87 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HGCOOKCJ_01839 3.7e-72 yjbI S Bacterial-like globin
HGCOOKCJ_01840 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HGCOOKCJ_01842 1.8e-20
HGCOOKCJ_01843 0.0 pepF E oligoendopeptidase F
HGCOOKCJ_01844 2.3e-223 yjbF S Competence protein
HGCOOKCJ_01845 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HGCOOKCJ_01846 6e-112 yjbE P Integral membrane protein TerC family
HGCOOKCJ_01847 2.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HGCOOKCJ_01848 6.9e-104 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGCOOKCJ_01849 8.6e-196 yjbB EGP Major Facilitator Superfamily
HGCOOKCJ_01850 5.5e-172 oppF E Belongs to the ABC transporter superfamily
HGCOOKCJ_01851 3e-198 oppD P Belongs to the ABC transporter superfamily
HGCOOKCJ_01852 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGCOOKCJ_01853 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGCOOKCJ_01854 0.0 oppA E ABC transporter substrate-binding protein
HGCOOKCJ_01855 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HGCOOKCJ_01856 5e-147 yjbA S Belongs to the UPF0736 family
HGCOOKCJ_01857 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGCOOKCJ_01858 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGCOOKCJ_01859 1.6e-251 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HGCOOKCJ_01860 6.5e-187 appF E Belongs to the ABC transporter superfamily
HGCOOKCJ_01861 1.8e-184 appD P Belongs to the ABC transporter superfamily
HGCOOKCJ_01862 7.8e-151 yjaZ O Zn-dependent protease
HGCOOKCJ_01863 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HGCOOKCJ_01864 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HGCOOKCJ_01865 2.7e-22 yjzB
HGCOOKCJ_01866 7.3e-26 comZ S ComZ
HGCOOKCJ_01867 1.1e-183 med S Transcriptional activator protein med
HGCOOKCJ_01868 7.3e-103 yjaV
HGCOOKCJ_01869 6.2e-142 yjaU I carboxylic ester hydrolase activity
HGCOOKCJ_01870 2.3e-16 yjzD S Protein of unknown function (DUF2929)
HGCOOKCJ_01871 9.5e-28 yjzC S YjzC-like protein
HGCOOKCJ_01872 4.2e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HGCOOKCJ_01873 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HGCOOKCJ_01874 3.9e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HGCOOKCJ_01875 4.4e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HGCOOKCJ_01876 2.2e-137 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HGCOOKCJ_01877 3.1e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HGCOOKCJ_01878 5.4e-200 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HGCOOKCJ_01879 1.7e-88 norB G Major Facilitator Superfamily
HGCOOKCJ_01880 4.3e-272 yitY C D-arabinono-1,4-lactone oxidase
HGCOOKCJ_01881 1.5e-22 pilT S Proteolipid membrane potential modulator
HGCOOKCJ_01882 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HGCOOKCJ_01883 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HGCOOKCJ_01884 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HGCOOKCJ_01885 1.2e-17 S Protein of unknown function (DUF3813)
HGCOOKCJ_01886 1.9e-72 ipi S Intracellular proteinase inhibitor
HGCOOKCJ_01887 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HGCOOKCJ_01888 8.4e-159 yitS S protein conserved in bacteria
HGCOOKCJ_01889 2.2e-311 nprB 3.4.24.28 E Peptidase M4
HGCOOKCJ_01890 1.4e-44 yitR S Domain of unknown function (DUF3784)
HGCOOKCJ_01891 2e-95
HGCOOKCJ_01892 1.5e-58 K Transcriptional regulator PadR-like family
HGCOOKCJ_01893 1.5e-97 S Sporulation delaying protein SdpA
HGCOOKCJ_01894 2.8e-171
HGCOOKCJ_01895 8.5e-94
HGCOOKCJ_01896 4e-161 cvfB S protein conserved in bacteria
HGCOOKCJ_01897 8.6e-55 yajQ S Belongs to the UPF0234 family
HGCOOKCJ_01898 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HGCOOKCJ_01899 5.8e-82 yjcF S Acetyltransferase (GNAT) domain
HGCOOKCJ_01900 1.8e-161 yitH K Acetyltransferase (GNAT) domain
HGCOOKCJ_01901 4e-229 yitG EGP Major facilitator Superfamily
HGCOOKCJ_01902 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HGCOOKCJ_01903 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HGCOOKCJ_01904 1.9e-141 yitD 4.4.1.19 S synthase
HGCOOKCJ_01905 4.9e-125 comB 3.1.3.71 H Belongs to the ComB family
HGCOOKCJ_01906 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HGCOOKCJ_01907 3.2e-233 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HGCOOKCJ_01908 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
HGCOOKCJ_01909 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HGCOOKCJ_01910 4e-36 mcbG S Pentapeptide repeats (9 copies)
HGCOOKCJ_01911 1.7e-281 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HGCOOKCJ_01912 6.4e-108 argO S Lysine exporter protein LysE YggA
HGCOOKCJ_01913 1.3e-93 yisT S DinB family
HGCOOKCJ_01914 4.5e-199 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
HGCOOKCJ_01915 2.4e-184 purR K helix_turn _helix lactose operon repressor
HGCOOKCJ_01916 1.2e-160 yisR K Transcriptional regulator
HGCOOKCJ_01917 4e-243 yisQ V Mate efflux family protein
HGCOOKCJ_01918 6.8e-150 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
HGCOOKCJ_01919 2.1e-88 yizA S Damage-inducible protein DinB
HGCOOKCJ_01920 0.0 asnO 6.3.5.4 E Asparagine synthase
HGCOOKCJ_01921 7.2e-106 yisN S Protein of unknown function (DUF2777)
HGCOOKCJ_01922 0.0 wprA O Belongs to the peptidase S8 family
HGCOOKCJ_01923 3e-57 yisL S UPF0344 protein
HGCOOKCJ_01924 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HGCOOKCJ_01925 1.7e-176 cotH M Spore Coat
HGCOOKCJ_01926 1.5e-22 yisI S Spo0E like sporulation regulatory protein
HGCOOKCJ_01927 1.9e-33 gerPA S Spore germination protein
HGCOOKCJ_01928 4e-34 gerPB S cell differentiation
HGCOOKCJ_01929 1.8e-54 gerPC S Spore germination protein
HGCOOKCJ_01930 6.3e-24 gerPD S Spore germination protein
HGCOOKCJ_01931 3e-66 gerPE S Spore germination protein GerPE
HGCOOKCJ_01932 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
HGCOOKCJ_01933 6e-51 yisB V COG1403 Restriction endonuclease
HGCOOKCJ_01934 0.0 sbcC L COG0419 ATPase involved in DNA repair
HGCOOKCJ_01935 1.7e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HGCOOKCJ_01936 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HGCOOKCJ_01937 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HGCOOKCJ_01938 2.2e-78 yhjR S Rubrerythrin
HGCOOKCJ_01939 2e-36 yhjQ C COG1145 Ferredoxin
HGCOOKCJ_01940 0.0 S Sugar transport-related sRNA regulator N-term
HGCOOKCJ_01941 3.1e-215 EGP Transmembrane secretion effector
HGCOOKCJ_01942 3.8e-202 abrB S membrane
HGCOOKCJ_01943 1.6e-188 yhjM 5.1.1.1 K Transcriptional regulator
HGCOOKCJ_01944 4.4e-255 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
HGCOOKCJ_01945 1.8e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
HGCOOKCJ_01946 1.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
HGCOOKCJ_01947 6.9e-215 glcP G Major Facilitator Superfamily
HGCOOKCJ_01948 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
HGCOOKCJ_01949 1.1e-286 yhjG CH FAD binding domain
HGCOOKCJ_01950 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HGCOOKCJ_01951 9.1e-110 yhjE S SNARE associated Golgi protein
HGCOOKCJ_01952 5e-60 yhjD
HGCOOKCJ_01953 6.9e-27 yhjC S Protein of unknown function (DUF3311)
HGCOOKCJ_01954 6.1e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HGCOOKCJ_01955 7.8e-42 yhjA S Excalibur calcium-binding domain
HGCOOKCJ_01956 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
HGCOOKCJ_01957 4.2e-109 comK K Competence transcription factor
HGCOOKCJ_01958 1.3e-32 yhzC S IDEAL
HGCOOKCJ_01959 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGCOOKCJ_01960 1.1e-302 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HGCOOKCJ_01961 1.7e-182 hemAT NT chemotaxis protein
HGCOOKCJ_01962 5e-91 bioY S BioY family
HGCOOKCJ_01963 1e-281 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HGCOOKCJ_01964 2.3e-201 vraB 2.3.1.9 I Belongs to the thiolase family
HGCOOKCJ_01965 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HGCOOKCJ_01966 4.3e-159 yfmC M Periplasmic binding protein
HGCOOKCJ_01967 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
HGCOOKCJ_01968 9.2e-80 VY92_01935 K acetyltransferase
HGCOOKCJ_01969 2.3e-204 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HGCOOKCJ_01970 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
HGCOOKCJ_01971 1.9e-65 yhfM
HGCOOKCJ_01972 7.3e-302 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HGCOOKCJ_01973 2.6e-112 yhfK GM NmrA-like family
HGCOOKCJ_01974 2e-191 lplJ 6.3.1.20 H Lipoate-protein ligase
HGCOOKCJ_01975 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HGCOOKCJ_01976 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HGCOOKCJ_01977 1.7e-72 3.4.13.21 S ASCH
HGCOOKCJ_01978 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HGCOOKCJ_01979 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
HGCOOKCJ_01980 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HGCOOKCJ_01981 1e-238 yhgE S YhgE Pip N-terminal domain protein
HGCOOKCJ_01982 1.4e-101 yhgD K Transcriptional regulator
HGCOOKCJ_01983 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HGCOOKCJ_01984 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HGCOOKCJ_01985 1.7e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HGCOOKCJ_01986 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HGCOOKCJ_01987 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HGCOOKCJ_01988 7.5e-17 1.15.1.2 C Rubrerythrin
HGCOOKCJ_01989 4.2e-248 yhfA C membrane
HGCOOKCJ_01990 2.3e-231 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HGCOOKCJ_01991 4.8e-115 ecsC S EcsC protein family
HGCOOKCJ_01992 1.8e-215 ecsB U ABC transporter
HGCOOKCJ_01993 4.6e-137 ecsA V transporter (ATP-binding protein)
HGCOOKCJ_01994 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HGCOOKCJ_01995 9.9e-205 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HGCOOKCJ_01996 3.6e-80 trpP S Tryptophan transporter TrpP
HGCOOKCJ_01997 7e-39 yhaH S YtxH-like protein
HGCOOKCJ_01998 1e-113 hpr K Negative regulator of protease production and sporulation
HGCOOKCJ_01999 1.3e-54 yhaI S Protein of unknown function (DUF1878)
HGCOOKCJ_02000 8.7e-90 yhaK S Putative zincin peptidase
HGCOOKCJ_02001 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HGCOOKCJ_02002 1.6e-21 yhaL S Sporulation protein YhaL
HGCOOKCJ_02003 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
HGCOOKCJ_02004 0.0 yhaN L AAA domain
HGCOOKCJ_02005 3.6e-227 yhaO L DNA repair exonuclease
HGCOOKCJ_02006 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HGCOOKCJ_02007 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
HGCOOKCJ_02008 1.1e-26 S YhzD-like protein
HGCOOKCJ_02009 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
HGCOOKCJ_02011 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HGCOOKCJ_02012 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
HGCOOKCJ_02013 7.1e-294 hemZ H coproporphyrinogen III oxidase
HGCOOKCJ_02014 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
HGCOOKCJ_02015 3.1e-206 yhaZ L DNA alkylation repair enzyme
HGCOOKCJ_02016 9.5e-48 yheA S Belongs to the UPF0342 family
HGCOOKCJ_02017 6.7e-204 yheB S Belongs to the UPF0754 family
HGCOOKCJ_02018 4.3e-216 yheC HJ YheC/D like ATP-grasp
HGCOOKCJ_02019 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HGCOOKCJ_02020 1.3e-36 yheE S Family of unknown function (DUF5342)
HGCOOKCJ_02021 6.3e-28 sspB S spore protein
HGCOOKCJ_02022 3.7e-111 yheG GM NAD(P)H-binding
HGCOOKCJ_02023 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HGCOOKCJ_02024 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HGCOOKCJ_02025 3.4e-84 nhaX T Belongs to the universal stress protein A family
HGCOOKCJ_02026 2.2e-233 nhaC C Na H antiporter
HGCOOKCJ_02027 1.1e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HGCOOKCJ_02028 1.7e-151 yheN G deacetylase
HGCOOKCJ_02029 1.2e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HGCOOKCJ_02030 6.6e-204 yhdY M Mechanosensitive ion channel
HGCOOKCJ_02032 3.3e-135 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HGCOOKCJ_02033 5.1e-66 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HGCOOKCJ_02034 2.8e-47 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HGCOOKCJ_02035 1.1e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HGCOOKCJ_02036 1.4e-223 yhdR 2.6.1.1 E Aminotransferase
HGCOOKCJ_02037 4.1e-74 cueR K transcriptional
HGCOOKCJ_02038 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HGCOOKCJ_02039 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HGCOOKCJ_02040 1.5e-191 yhdN C Aldo keto reductase
HGCOOKCJ_02041 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HGCOOKCJ_02042 6.6e-201 yhdL S Sigma factor regulator N-terminal
HGCOOKCJ_02043 8.1e-45 yhdK S Sigma-M inhibitor protein
HGCOOKCJ_02044 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGCOOKCJ_02045 3.7e-276 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HGCOOKCJ_02046 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HGCOOKCJ_02047 3.4e-250 yhdG E amino acid
HGCOOKCJ_02048 4.9e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGCOOKCJ_02049 1.4e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
HGCOOKCJ_02050 3.8e-162 citR K Transcriptional regulator
HGCOOKCJ_02051 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HGCOOKCJ_02052 5.8e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HGCOOKCJ_02053 2.1e-276 ycgB S Stage V sporulation protein R
HGCOOKCJ_02054 8.7e-239 ygxB M Conserved TM helix
HGCOOKCJ_02055 3.5e-76 nsrR K Transcriptional regulator
HGCOOKCJ_02056 7.9e-189 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HGCOOKCJ_02057 4.8e-54 yhdC S Protein of unknown function (DUF3889)
HGCOOKCJ_02058 1.2e-38 yhdB S YhdB-like protein
HGCOOKCJ_02059 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
HGCOOKCJ_02060 1.1e-113 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGCOOKCJ_02061 5.5e-214 yhcY 2.7.13.3 T Histidine kinase
HGCOOKCJ_02062 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HGCOOKCJ_02063 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HGCOOKCJ_02064 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HGCOOKCJ_02065 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HGCOOKCJ_02066 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HGCOOKCJ_02067 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HGCOOKCJ_02068 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HGCOOKCJ_02069 4.6e-120 yhcW 5.4.2.6 S hydrolase
HGCOOKCJ_02070 9.9e-68 yhcV S COG0517 FOG CBS domain
HGCOOKCJ_02071 9.3e-68 yhcU S Family of unknown function (DUF5365)
HGCOOKCJ_02072 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HGCOOKCJ_02073 7.6e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HGCOOKCJ_02074 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
HGCOOKCJ_02075 5.2e-100 yhcQ M Spore coat protein
HGCOOKCJ_02076 2.5e-167 yhcP
HGCOOKCJ_02077 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HGCOOKCJ_02078 3.7e-44 yhcM
HGCOOKCJ_02079 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HGCOOKCJ_02080 1.2e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HGCOOKCJ_02081 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
HGCOOKCJ_02082 1e-30 cspB K Cold-shock protein
HGCOOKCJ_02083 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HGCOOKCJ_02084 2.6e-166 yhcH V ABC transporter, ATP-binding protein
HGCOOKCJ_02085 1.6e-123 yhcG V ABC transporter, ATP-binding protein
HGCOOKCJ_02086 6.6e-60 yhcF K Transcriptional regulator
HGCOOKCJ_02087 7.8e-55
HGCOOKCJ_02088 2.8e-37 yhcC
HGCOOKCJ_02089 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
HGCOOKCJ_02090 3.1e-271 yhcA EGP Major facilitator Superfamily
HGCOOKCJ_02091 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
HGCOOKCJ_02092 2.2e-76 yhbI K DNA-binding transcription factor activity
HGCOOKCJ_02093 2.5e-225 yhbH S Belongs to the UPF0229 family
HGCOOKCJ_02094 0.0 prkA T Ser protein kinase
HGCOOKCJ_02095 9.1e-74 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
HGCOOKCJ_02096 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HGCOOKCJ_02097 1.2e-109 yhbD K Protein of unknown function (DUF4004)
HGCOOKCJ_02098 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HGCOOKCJ_02099 4.4e-177 yhbB S Putative amidase domain
HGCOOKCJ_02100 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HGCOOKCJ_02101 7.9e-114 yhzB S B3/4 domain
HGCOOKCJ_02103 4.4e-29 K Transcriptional regulator
HGCOOKCJ_02104 4.1e-78 ygaO
HGCOOKCJ_02105 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HGCOOKCJ_02107 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HGCOOKCJ_02108 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HGCOOKCJ_02109 1.7e-171 ssuA M Sulfonate ABC transporter
HGCOOKCJ_02110 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HGCOOKCJ_02111 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HGCOOKCJ_02113 1.9e-266 ygaK C Berberine and berberine like
HGCOOKCJ_02114 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HGCOOKCJ_02115 5.9e-134 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HGCOOKCJ_02116 3e-27
HGCOOKCJ_02117 2.7e-143 spo0M S COG4326 Sporulation control protein
HGCOOKCJ_02121 2e-08
HGCOOKCJ_02129 7.8e-08
HGCOOKCJ_02134 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HGCOOKCJ_02135 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HGCOOKCJ_02136 1.8e-37 yaaB S Domain of unknown function (DUF370)
HGCOOKCJ_02137 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HGCOOKCJ_02138 2.4e-33 yaaA S S4 domain
HGCOOKCJ_02139 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HGCOOKCJ_02140 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HGCOOKCJ_02141 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HGCOOKCJ_02142 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HGCOOKCJ_02143 6.5e-108 jag S single-stranded nucleic acid binding R3H
HGCOOKCJ_02144 3.1e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HGCOOKCJ_02145 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HGCOOKCJ_02146 2.2e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HGCOOKCJ_02147 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HGCOOKCJ_02148 1.5e-74 S Bacterial PH domain
HGCOOKCJ_02149 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
HGCOOKCJ_02150 2.1e-149 spo0J K Belongs to the ParB family
HGCOOKCJ_02151 1.6e-111 yyaC S Sporulation protein YyaC
HGCOOKCJ_02152 8.1e-177 yyaD S Membrane
HGCOOKCJ_02153 2.3e-33 yyzM S protein conserved in bacteria
HGCOOKCJ_02154 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HGCOOKCJ_02155 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HGCOOKCJ_02156 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HGCOOKCJ_02157 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HGCOOKCJ_02158 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HGCOOKCJ_02159 8.1e-145 xth 3.1.11.2 L exodeoxyribonuclease III
HGCOOKCJ_02160 3.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HGCOOKCJ_02161 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGCOOKCJ_02162 5.1e-96 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
HGCOOKCJ_02163 3.8e-246 EGP Major facilitator superfamily
HGCOOKCJ_02164 9.5e-169 yyaK S CAAX protease self-immunity
HGCOOKCJ_02165 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HGCOOKCJ_02166 3.3e-161 yyaM EG EamA-like transporter family
HGCOOKCJ_02167 5.1e-61 yyaN K MerR HTH family regulatory protein
HGCOOKCJ_02168 9.7e-44 yyaL O Highly conserved protein containing a thioredoxin domain
HGCOOKCJ_02169 1.7e-249 tetL EGP Major facilitator Superfamily
HGCOOKCJ_02170 1.7e-107 yyaP 1.5.1.3 H RibD C-terminal domain
HGCOOKCJ_02171 5.4e-67 yyaQ S YjbR
HGCOOKCJ_02172 5.4e-100 yyaR K Acetyltransferase (GNAT) domain
HGCOOKCJ_02173 1.5e-101 yyaS S Membrane
HGCOOKCJ_02174 5.9e-79 yjcF S Acetyltransferase (GNAT) domain
HGCOOKCJ_02175 5.6e-77 yybA 2.3.1.57 K transcriptional
HGCOOKCJ_02176 3e-127 S Metallo-beta-lactamase superfamily
HGCOOKCJ_02177 2.7e-77 yybC
HGCOOKCJ_02178 2e-79 yjcF S Acetyltransferase (GNAT) domain
HGCOOKCJ_02179 2.1e-165 yybE K Transcriptional regulator
HGCOOKCJ_02180 3.2e-220 ynfM EGP Major facilitator Superfamily
HGCOOKCJ_02181 3e-124 yybG S Pentapeptide repeat-containing protein
HGCOOKCJ_02182 5.9e-67 yybH S SnoaL-like domain
HGCOOKCJ_02183 6.2e-132
HGCOOKCJ_02184 2.6e-115 V ATPases associated with a variety of cellular activities
HGCOOKCJ_02185 2e-127 S Protein of unknown function (DUF2705)
HGCOOKCJ_02186 9e-122
HGCOOKCJ_02187 4.1e-125
HGCOOKCJ_02188 1.3e-78 yybN S Protein of unknown function (DUF2712)
HGCOOKCJ_02189 1e-16
HGCOOKCJ_02190 2.3e-240 yybO G COG0477 Permeases of the major facilitator superfamily
HGCOOKCJ_02192 1.3e-70
HGCOOKCJ_02193 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HGCOOKCJ_02194 1.4e-68 ydeP3 K Transcriptional regulator
HGCOOKCJ_02195 3.9e-84 cotF M Spore coat protein
HGCOOKCJ_02197 2.9e-160 yybS S membrane
HGCOOKCJ_02198 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HGCOOKCJ_02199 2.2e-73 rplI J binds to the 23S rRNA
HGCOOKCJ_02200 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HGCOOKCJ_02201 8.4e-221 yeaN P COG2807 Cyanate permease
HGCOOKCJ_02202 1.9e-15 yycC K YycC-like protein
HGCOOKCJ_02204 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HGCOOKCJ_02205 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HGCOOKCJ_02206 8e-78 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGCOOKCJ_02207 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HGCOOKCJ_02212 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGCOOKCJ_02213 0.0 vicK 2.7.13.3 T Histidine kinase
HGCOOKCJ_02214 3.6e-260 yycH S protein conserved in bacteria
HGCOOKCJ_02215 7.3e-155 yycI S protein conserved in bacteria
HGCOOKCJ_02216 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HGCOOKCJ_02217 8.4e-221 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HGCOOKCJ_02218 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HGCOOKCJ_02219 1.7e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HGCOOKCJ_02220 9.7e-261 rocE E amino acid
HGCOOKCJ_02221 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HGCOOKCJ_02223 5e-188 S aspartate phosphatase
HGCOOKCJ_02224 3.1e-86 yycN 2.3.1.128 K Acetyltransferase
HGCOOKCJ_02225 5.8e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HGCOOKCJ_02226 1.6e-221 yycP
HGCOOKCJ_02227 2.1e-33 yycQ S Protein of unknown function (DUF2651)
HGCOOKCJ_02229 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HGCOOKCJ_02230 4.2e-71
HGCOOKCJ_02231 1.1e-09 S YyzF-like protein
HGCOOKCJ_02232 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HGCOOKCJ_02233 7.3e-280 S Calcineurin-like phosphoesterase
HGCOOKCJ_02234 3.5e-65
HGCOOKCJ_02235 0.0 S Uncharacterised protein conserved in bacteria (DUF2326)
HGCOOKCJ_02236 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
HGCOOKCJ_02237 8e-12
HGCOOKCJ_02238 7.7e-185 S Radical SAM superfamily
HGCOOKCJ_02239 8.4e-134 yydH O Peptidase M50
HGCOOKCJ_02240 1.8e-110 prrC P ABC transporter
HGCOOKCJ_02241 3.3e-119 S ABC-2 family transporter protein
HGCOOKCJ_02242 7.6e-13
HGCOOKCJ_02243 1.3e-128 yydK K Transcriptional regulator
HGCOOKCJ_02244 2.5e-19 bglF G phosphotransferase system
HGCOOKCJ_02245 6.4e-292 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HGCOOKCJ_02246 3.8e-287 ahpF O Alkyl hydroperoxide reductase
HGCOOKCJ_02247 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HGCOOKCJ_02248 3.8e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HGCOOKCJ_02249 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
HGCOOKCJ_02250 4.6e-304 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HGCOOKCJ_02251 7.3e-127 gntR K transcriptional
HGCOOKCJ_02252 7e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HGCOOKCJ_02253 1.3e-193 yxaB GM Polysaccharide pyruvyl transferase
HGCOOKCJ_02254 2.6e-118 yxaC M effector of murein hydrolase
HGCOOKCJ_02255 5.2e-50 S LrgA family
HGCOOKCJ_02256 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
HGCOOKCJ_02257 2.3e-201 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HGCOOKCJ_02258 7.1e-101 yxaF K Transcriptional regulator
HGCOOKCJ_02259 1.5e-199 yxaG 1.13.11.24 S AraC-like ligand binding domain
HGCOOKCJ_02260 1.4e-228 P Protein of unknown function (DUF418)
HGCOOKCJ_02261 1.1e-75 yxaI S membrane protein domain
HGCOOKCJ_02262 3.5e-65 S Family of unknown function (DUF5391)
HGCOOKCJ_02263 6.8e-93 S PQQ-like domain
HGCOOKCJ_02264 7.6e-214 yxaM U MFS_1 like family
HGCOOKCJ_02265 0.0 asnB 6.3.5.4 E Asparagine synthase
HGCOOKCJ_02266 1.1e-86 yxnB
HGCOOKCJ_02267 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
HGCOOKCJ_02268 3.3e-127 yxbB Q Met-10+ like-protein
HGCOOKCJ_02269 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
HGCOOKCJ_02270 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
HGCOOKCJ_02271 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HGCOOKCJ_02272 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
HGCOOKCJ_02273 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
HGCOOKCJ_02275 0.0 htpG O Molecular chaperone. Has ATPase activity
HGCOOKCJ_02276 2.3e-246 csbC EGP Major facilitator Superfamily
HGCOOKCJ_02277 8.3e-48 yxcD S Protein of unknown function (DUF2653)
HGCOOKCJ_02279 3.7e-176 iolS C Aldo keto reductase
HGCOOKCJ_02280 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
HGCOOKCJ_02281 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HGCOOKCJ_02282 1.1e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HGCOOKCJ_02283 2.9e-179 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HGCOOKCJ_02284 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HGCOOKCJ_02285 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HGCOOKCJ_02286 1.3e-235 iolF EGP Major facilitator Superfamily
HGCOOKCJ_02287 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HGCOOKCJ_02288 2.3e-167 iolH G Xylose isomerase-like TIM barrel
HGCOOKCJ_02289 1.9e-139 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HGCOOKCJ_02290 5.4e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HGCOOKCJ_02291 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGCOOKCJ_02292 1.3e-182 T PhoQ Sensor
HGCOOKCJ_02293 9.4e-141 yxdL V ABC transporter, ATP-binding protein
HGCOOKCJ_02294 0.0 yxdM V ABC transporter (permease)
HGCOOKCJ_02295 1.5e-58 yxeA S Protein of unknown function (DUF1093)
HGCOOKCJ_02296 6e-177 fhuD P ABC transporter
HGCOOKCJ_02297 8.5e-69
HGCOOKCJ_02298 1.9e-16 yxeD
HGCOOKCJ_02299 1.3e-20 yxeE
HGCOOKCJ_02302 6.2e-151 yidA S hydrolases of the HAD superfamily
HGCOOKCJ_02303 8.8e-192 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HGCOOKCJ_02305 2.2e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGCOOKCJ_02306 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGCOOKCJ_02307 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
HGCOOKCJ_02308 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
HGCOOKCJ_02309 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HGCOOKCJ_02310 3.8e-215 yxeP 3.5.1.47 E hydrolase activity
HGCOOKCJ_02311 2e-255 yxeQ S MmgE/PrpD family
HGCOOKCJ_02312 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
HGCOOKCJ_02313 3e-153 yxxB S Domain of Unknown Function (DUF1206)
HGCOOKCJ_02314 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HGCOOKCJ_02315 7e-116 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HGCOOKCJ_02316 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HGCOOKCJ_02317 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HGCOOKCJ_02318 6.1e-252 lysP E amino acid
HGCOOKCJ_02319 8e-182 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HGCOOKCJ_02320 1.2e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HGCOOKCJ_02321 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HGCOOKCJ_02322 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
HGCOOKCJ_02323 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HGCOOKCJ_02324 6.3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HGCOOKCJ_02325 2.1e-21 S Domain of unknown function (DUF5082)
HGCOOKCJ_02326 3.6e-39 yxiC S Family of unknown function (DUF5344)
HGCOOKCJ_02327 0.0 S nuclease activity
HGCOOKCJ_02328 2.2e-78 S SMI1 / KNR4 family
HGCOOKCJ_02329 3.6e-51
HGCOOKCJ_02330 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HGCOOKCJ_02331 6.6e-281 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HGCOOKCJ_02332 1.1e-72 yxiE T Belongs to the universal stress protein A family
HGCOOKCJ_02333 2.9e-168 yxxF EG EamA-like transporter family
HGCOOKCJ_02334 0.0 wapA M COG3209 Rhs family protein
HGCOOKCJ_02335 1.5e-71 yxxG
HGCOOKCJ_02336 1.7e-84
HGCOOKCJ_02337 6.4e-63
HGCOOKCJ_02338 3.7e-75 yxiG
HGCOOKCJ_02339 4.9e-46
HGCOOKCJ_02340 3.8e-81
HGCOOKCJ_02341 1.2e-96 yxiI S Protein of unknown function (DUF2716)
HGCOOKCJ_02342 1.6e-48 yxiJ S YxiJ-like protein
HGCOOKCJ_02345 7.5e-219 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
HGCOOKCJ_02346 1e-265 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HGCOOKCJ_02347 3e-232 yxiO S COG2270 Permeases of the major facilitator superfamily
HGCOOKCJ_02348 6.6e-114
HGCOOKCJ_02349 8.3e-151 licT K transcriptional antiterminator
HGCOOKCJ_02350 5e-144 exoK GH16 M licheninase activity
HGCOOKCJ_02351 6.6e-224 citH C Citrate transporter
HGCOOKCJ_02352 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HGCOOKCJ_02353 2.7e-48 yxiS
HGCOOKCJ_02354 1.2e-22 T Domain of unknown function (DUF4163)
HGCOOKCJ_02355 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HGCOOKCJ_02356 2.2e-145 rlmA 2.1.1.187 Q Methyltransferase domain
HGCOOKCJ_02357 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
HGCOOKCJ_02358 1.4e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HGCOOKCJ_02359 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HGCOOKCJ_02360 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HGCOOKCJ_02361 1e-220 yxjG 2.1.1.14 E Methionine synthase
HGCOOKCJ_02362 5.5e-222 yxjG 2.1.1.14 E Methionine synthase
HGCOOKCJ_02363 1e-87 yxjI S LURP-one-related
HGCOOKCJ_02366 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HGCOOKCJ_02367 8.9e-116 K helix_turn_helix, Lux Regulon
HGCOOKCJ_02368 1.5e-193 yxjM T Signal transduction histidine kinase
HGCOOKCJ_02369 2.4e-78 S Protein of unknown function (DUF1453)
HGCOOKCJ_02370 1.9e-166 yxjO K LysR substrate binding domain
HGCOOKCJ_02371 1.3e-95 yxkA S Phosphatidylethanolamine-binding protein
HGCOOKCJ_02372 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HGCOOKCJ_02373 4.1e-73 yxkC S Domain of unknown function (DUF4352)
HGCOOKCJ_02374 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HGCOOKCJ_02375 2.5e-275 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HGCOOKCJ_02376 4.8e-165 lrp QT PucR C-terminal helix-turn-helix domain
HGCOOKCJ_02377 5.9e-205 msmK P Belongs to the ABC transporter superfamily
HGCOOKCJ_02378 3e-156 yxkH G Polysaccharide deacetylase
HGCOOKCJ_02380 0.0 3.4.24.84 O Peptidase family M48
HGCOOKCJ_02381 1.5e-229 cimH C COG3493 Na citrate symporter
HGCOOKCJ_02382 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
HGCOOKCJ_02383 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HGCOOKCJ_02384 0.0 cydD V ATP-binding
HGCOOKCJ_02385 0.0 cydD V ATP-binding protein
HGCOOKCJ_02386 8e-162 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HGCOOKCJ_02387 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HGCOOKCJ_02388 4.7e-91 sigY K Belongs to the sigma-70 factor family. ECF subfamily
HGCOOKCJ_02389 3.9e-48 yxlC S Family of unknown function (DUF5345)
HGCOOKCJ_02390 1.2e-31
HGCOOKCJ_02391 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
HGCOOKCJ_02392 5.1e-167 yxlF V ABC transporter, ATP-binding protein
HGCOOKCJ_02393 1.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HGCOOKCJ_02394 2.1e-216 yxlH EGP Major facilitator Superfamily
HGCOOKCJ_02395 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HGCOOKCJ_02396 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HGCOOKCJ_02397 1.1e-19 yxzF
HGCOOKCJ_02398 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HGCOOKCJ_02399 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HGCOOKCJ_02400 7.4e-250 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGCOOKCJ_02401 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HGCOOKCJ_02402 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HGCOOKCJ_02403 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HGCOOKCJ_02404 6.6e-139 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HGCOOKCJ_02405 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HGCOOKCJ_02406 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGCOOKCJ_02407 1.2e-232 dltB M membrane protein involved in D-alanine export
HGCOOKCJ_02408 7.9e-293 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGCOOKCJ_02409 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HGCOOKCJ_02410 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
HGCOOKCJ_02411 1.4e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HGCOOKCJ_02412 4.4e-233 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HGCOOKCJ_02413 8.1e-88 ywaE K Transcriptional regulator
HGCOOKCJ_02414 1.7e-128 ywaF S Integral membrane protein
HGCOOKCJ_02415 7e-169 gspA M General stress
HGCOOKCJ_02416 4e-153 sacY K transcriptional antiterminator
HGCOOKCJ_02417 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HGCOOKCJ_02418 1.6e-277 epr 3.4.21.62 O Belongs to the peptidase S8 family
HGCOOKCJ_02419 5.8e-247 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGCOOKCJ_02420 1.8e-127 ywbB S Protein of unknown function (DUF2711)
HGCOOKCJ_02421 4.4e-67 ywbC 4.4.1.5 E glyoxalase
HGCOOKCJ_02422 8.9e-223 ywbD 2.1.1.191 J Methyltransferase
HGCOOKCJ_02423 1.2e-28 ywbE S Uncharacterized conserved protein (DUF2196)
HGCOOKCJ_02424 1.9e-209 ywbF EGP Major facilitator Superfamily
HGCOOKCJ_02425 2.3e-111 ywbG M effector of murein hydrolase
HGCOOKCJ_02426 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HGCOOKCJ_02427 4.3e-153 ywbI K Transcriptional regulator
HGCOOKCJ_02428 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HGCOOKCJ_02429 4.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HGCOOKCJ_02430 8.2e-255 P COG0672 High-affinity Fe2 Pb2 permease
HGCOOKCJ_02431 2e-187 ycdO P periplasmic lipoprotein involved in iron transport
HGCOOKCJ_02432 2.6e-225 ywbN P Dyp-type peroxidase family protein
HGCOOKCJ_02433 1.9e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HGCOOKCJ_02434 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HGCOOKCJ_02435 9.8e-49 ywcB S Protein of unknown function, DUF485
HGCOOKCJ_02437 2.2e-122 ywcC K transcriptional regulator
HGCOOKCJ_02438 9.5e-60 gtcA S GtrA-like protein
HGCOOKCJ_02439 6.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HGCOOKCJ_02440 3.7e-306 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HGCOOKCJ_02441 1e-35 ywzA S membrane
HGCOOKCJ_02442 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HGCOOKCJ_02443 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HGCOOKCJ_02444 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HGCOOKCJ_02445 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HGCOOKCJ_02446 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
HGCOOKCJ_02447 2.9e-202 rodA D Belongs to the SEDS family
HGCOOKCJ_02448 7.2e-138 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HGCOOKCJ_02449 5.1e-187 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGCOOKCJ_02450 0.0 vpr O Belongs to the peptidase S8 family
HGCOOKCJ_02452 2.4e-150 sacT K transcriptional antiterminator
HGCOOKCJ_02453 1e-139 focA P Formate/nitrite transporter
HGCOOKCJ_02454 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HGCOOKCJ_02455 9.5e-296 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
HGCOOKCJ_02456 2e-28 ywdA
HGCOOKCJ_02457 9.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HGCOOKCJ_02458 1.3e-57 pex K Transcriptional regulator PadR-like family
HGCOOKCJ_02459 1.4e-113 ywdD
HGCOOKCJ_02461 1.1e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
HGCOOKCJ_02462 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HGCOOKCJ_02463 5.9e-263 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HGCOOKCJ_02464 7.7e-49 ywdI S Family of unknown function (DUF5327)
HGCOOKCJ_02465 1.3e-238 ywdJ F Xanthine uracil
HGCOOKCJ_02466 4.3e-59 ywdK S small membrane protein
HGCOOKCJ_02467 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HGCOOKCJ_02468 2.8e-145 spsA M Spore Coat
HGCOOKCJ_02469 1.5e-269 spsB M Capsule polysaccharide biosynthesis protein
HGCOOKCJ_02470 1.6e-224 spsC E Belongs to the DegT DnrJ EryC1 family
HGCOOKCJ_02471 4e-164 spsD 2.3.1.210 K Spore Coat
HGCOOKCJ_02472 3.2e-214 spsE 2.5.1.56 M acid synthase
HGCOOKCJ_02473 9.7e-132 spsF M Spore Coat
HGCOOKCJ_02474 1.7e-190 spsG M Spore Coat
HGCOOKCJ_02475 1.9e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HGCOOKCJ_02476 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HGCOOKCJ_02477 5.3e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HGCOOKCJ_02478 3.5e-87 spsL 5.1.3.13 M Spore Coat
HGCOOKCJ_02479 1.8e-78
HGCOOKCJ_02480 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HGCOOKCJ_02481 1.4e-297 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HGCOOKCJ_02482 0.0 rocB E arginine degradation protein
HGCOOKCJ_02483 4e-262 lysP E amino acid
HGCOOKCJ_02484 4.6e-206 ywfA EGP Major facilitator Superfamily
HGCOOKCJ_02485 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HGCOOKCJ_02486 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HGCOOKCJ_02487 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGCOOKCJ_02488 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HGCOOKCJ_02489 2.9e-210 bacE EGP Major facilitator Superfamily
HGCOOKCJ_02490 2.7e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
HGCOOKCJ_02491 4e-139 IQ Enoyl-(Acyl carrier protein) reductase
HGCOOKCJ_02492 1.1e-146 ywfI C May function as heme-dependent peroxidase
HGCOOKCJ_02493 6.6e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HGCOOKCJ_02494 9.2e-164 cysL K Transcriptional regulator
HGCOOKCJ_02495 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HGCOOKCJ_02496 5.2e-159 ywfM EG EamA-like transporter family
HGCOOKCJ_02497 1.6e-111 rsfA_1
HGCOOKCJ_02498 3.1e-36 ywzC S Belongs to the UPF0741 family
HGCOOKCJ_02499 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
HGCOOKCJ_02500 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
HGCOOKCJ_02501 2.8e-79 yffB K Transcriptional regulator
HGCOOKCJ_02502 2.6e-242 mmr U Major Facilitator Superfamily
HGCOOKCJ_02504 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HGCOOKCJ_02505 3.3e-71 ywhA K Transcriptional regulator
HGCOOKCJ_02506 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HGCOOKCJ_02507 5.1e-119 ywhC S Peptidase family M50
HGCOOKCJ_02508 5.2e-95 ywhD S YwhD family
HGCOOKCJ_02509 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HGCOOKCJ_02510 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HGCOOKCJ_02511 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
HGCOOKCJ_02512 1e-84 ywhH S Aminoacyl-tRNA editing domain
HGCOOKCJ_02514 2.3e-79 S aspartate phosphatase
HGCOOKCJ_02515 2.5e-205 ywhK CO amine dehydrogenase activity
HGCOOKCJ_02516 2.9e-249 ywhL CO amine dehydrogenase activity
HGCOOKCJ_02518 1.2e-249 L Peptidase, M16
HGCOOKCJ_02519 2.7e-219 2.7.1.26, 2.7.7.2 L Peptidase, M16
HGCOOKCJ_02520 3.1e-237 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HGCOOKCJ_02521 3.3e-132 cbiO V ABC transporter
HGCOOKCJ_02523 2.6e-271 C Fe-S oxidoreductases
HGCOOKCJ_02524 1e-07 S Bacteriocin subtilosin A
HGCOOKCJ_02525 4.7e-73 ywiB S protein conserved in bacteria
HGCOOKCJ_02526 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HGCOOKCJ_02527 9.8e-214 narK P COG2223 Nitrate nitrite transporter
HGCOOKCJ_02528 5.3e-130 fnr K helix_turn_helix, cAMP Regulatory protein
HGCOOKCJ_02529 4.3e-140 ywiC S YwiC-like protein
HGCOOKCJ_02530 7e-86 arfM T cyclic nucleotide binding
HGCOOKCJ_02531 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HGCOOKCJ_02532 1e-297 narH 1.7.5.1 C Nitrate reductase, beta
HGCOOKCJ_02533 2.4e-98 narJ 1.7.5.1 C nitrate reductase
HGCOOKCJ_02534 1.8e-124 narI 1.7.5.1 C nitrate reductase, gamma
HGCOOKCJ_02535 6.4e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HGCOOKCJ_02536 0.0 ywjA V ABC transporter
HGCOOKCJ_02537 4.8e-96 ywjB H RibD C-terminal domain
HGCOOKCJ_02538 2.7e-42 ywjC
HGCOOKCJ_02539 6.6e-184 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HGCOOKCJ_02540 2.3e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HGCOOKCJ_02541 0.0 fadF C COG0247 Fe-S oxidoreductase
HGCOOKCJ_02542 2.6e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
HGCOOKCJ_02543 1.5e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HGCOOKCJ_02544 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HGCOOKCJ_02545 2.4e-92 ywjG S Domain of unknown function (DUF2529)
HGCOOKCJ_02546 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
HGCOOKCJ_02547 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HGCOOKCJ_02548 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HGCOOKCJ_02549 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HGCOOKCJ_02550 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HGCOOKCJ_02551 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HGCOOKCJ_02552 1.1e-32 rpmE J Binds the 23S rRNA
HGCOOKCJ_02553 2.4e-104 tdk 2.7.1.21 F thymidine kinase
HGCOOKCJ_02554 0.0 sfcA 1.1.1.38 C malic enzyme
HGCOOKCJ_02555 8.6e-160 ywkB S Membrane transport protein
HGCOOKCJ_02556 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HGCOOKCJ_02557 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGCOOKCJ_02558 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HGCOOKCJ_02559 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HGCOOKCJ_02561 3.4e-56 ywlA S Uncharacterised protein family (UPF0715)
HGCOOKCJ_02562 6.1e-112 spoIIR S stage II sporulation protein R
HGCOOKCJ_02563 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HGCOOKCJ_02564 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HGCOOKCJ_02565 1.7e-91 mntP P Probably functions as a manganese efflux pump
HGCOOKCJ_02566 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HGCOOKCJ_02567 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HGCOOKCJ_02568 7.2e-95 ywlG S Belongs to the UPF0340 family
HGCOOKCJ_02569 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HGCOOKCJ_02570 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HGCOOKCJ_02571 2.5e-62 atpI S ATP synthase
HGCOOKCJ_02572 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
HGCOOKCJ_02573 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HGCOOKCJ_02574 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HGCOOKCJ_02575 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HGCOOKCJ_02576 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HGCOOKCJ_02577 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HGCOOKCJ_02578 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HGCOOKCJ_02579 5.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HGCOOKCJ_02580 4.3e-88 ywmA
HGCOOKCJ_02581 1.3e-32 ywzB S membrane
HGCOOKCJ_02582 1.6e-134 ywmB S TATA-box binding
HGCOOKCJ_02583 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HGCOOKCJ_02584 2e-178 spoIID D Stage II sporulation protein D
HGCOOKCJ_02585 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HGCOOKCJ_02586 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HGCOOKCJ_02588 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HGCOOKCJ_02589 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HGCOOKCJ_02590 1.3e-103 S response regulator aspartate phosphatase
HGCOOKCJ_02591 3e-84 ywmF S Peptidase M50
HGCOOKCJ_02592 3.8e-11 csbD K CsbD-like
HGCOOKCJ_02594 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HGCOOKCJ_02595 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HGCOOKCJ_02596 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HGCOOKCJ_02597 1.7e-64 ywnA K Transcriptional regulator
HGCOOKCJ_02598 1.6e-114 ywnB S NAD(P)H-binding
HGCOOKCJ_02599 2.6e-59 ywnC S Family of unknown function (DUF5362)
HGCOOKCJ_02600 4.1e-144 mta K transcriptional
HGCOOKCJ_02601 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HGCOOKCJ_02602 2.2e-70 ywnF S Family of unknown function (DUF5392)
HGCOOKCJ_02603 2.7e-14 ywnC S Family of unknown function (DUF5362)
HGCOOKCJ_02604 6.4e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HGCOOKCJ_02605 5.5e-126 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HGCOOKCJ_02606 3.5e-73 ywnJ S VanZ like family
HGCOOKCJ_02607 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HGCOOKCJ_02608 1.6e-58 nrgB K Belongs to the P(II) protein family
HGCOOKCJ_02609 2.5e-225 amt P Ammonium transporter
HGCOOKCJ_02610 1.2e-77
HGCOOKCJ_02611 4e-104 phzA Q Isochorismatase family
HGCOOKCJ_02612 4.4e-242 ywoD EGP Major facilitator superfamily
HGCOOKCJ_02613 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HGCOOKCJ_02614 1.2e-231 ywoF P Right handed beta helix region
HGCOOKCJ_02615 2.7e-211 ywoG EGP Major facilitator Superfamily
HGCOOKCJ_02616 2.1e-70 ywoH K COG1846 Transcriptional regulators
HGCOOKCJ_02617 3e-44 spoIIID K Stage III sporulation protein D
HGCOOKCJ_02618 3.5e-180 mbl D Rod shape-determining protein
HGCOOKCJ_02619 6.9e-126 flhO N flagellar basal body
HGCOOKCJ_02620 1.5e-141 flhP N flagellar basal body
HGCOOKCJ_02621 2.1e-199 S aspartate phosphatase
HGCOOKCJ_02622 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HGCOOKCJ_02623 1.5e-54 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HGCOOKCJ_02624 1.9e-153 ywpD T Histidine kinase
HGCOOKCJ_02625 8e-51 srtA 3.4.22.70 M Sortase family
HGCOOKCJ_02626 1.1e-66 ywpF S YwpF-like protein
HGCOOKCJ_02627 1.3e-66 ywpG
HGCOOKCJ_02628 9.8e-58 ssbB L Single-stranded DNA-binding protein
HGCOOKCJ_02629 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
HGCOOKCJ_02630 3.6e-157 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HGCOOKCJ_02631 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HGCOOKCJ_02632 3.8e-309 ywqB S SWIM zinc finger
HGCOOKCJ_02633 1.2e-17
HGCOOKCJ_02634 2e-116 ywqC M biosynthesis protein
HGCOOKCJ_02635 1.1e-119 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HGCOOKCJ_02636 1.4e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HGCOOKCJ_02637 3e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HGCOOKCJ_02638 3.4e-154 ywqG S Domain of unknown function (DUF1963)
HGCOOKCJ_02639 3.3e-15 S Domain of unknown function (DUF5082)
HGCOOKCJ_02640 1.3e-38 ywqI S Family of unknown function (DUF5344)
HGCOOKCJ_02641 0.0 ywqJ L nucleic acid phosphodiester bond hydrolysis
HGCOOKCJ_02642 1.7e-52 S MORN repeat variant
HGCOOKCJ_02643 4.5e-137 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HGCOOKCJ_02644 2.9e-162 K Transcriptional regulator
HGCOOKCJ_02645 2.7e-102 ywqN S NAD(P)H-dependent
HGCOOKCJ_02647 6.9e-90 ywrA P COG2059 Chromate transport protein ChrA
HGCOOKCJ_02648 2.4e-104 ywrB P Chromate transporter
HGCOOKCJ_02649 2.1e-82 ywrC K Transcriptional regulator
HGCOOKCJ_02650 9.6e-310 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HGCOOKCJ_02651 2.9e-54 S Domain of unknown function (DUF4181)
HGCOOKCJ_02652 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HGCOOKCJ_02653 3.7e-12
HGCOOKCJ_02654 1.2e-210 cotH M Spore Coat
HGCOOKCJ_02655 7.6e-131 cotB
HGCOOKCJ_02656 7.5e-126 ywrJ
HGCOOKCJ_02657 1.9e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HGCOOKCJ_02658 1.1e-169 alsR K LysR substrate binding domain
HGCOOKCJ_02659 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HGCOOKCJ_02660 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HGCOOKCJ_02661 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
HGCOOKCJ_02662 3.6e-48 ywsA S Protein of unknown function (DUF3892)
HGCOOKCJ_02663 4.6e-94 batE T Sh3 type 3 domain protein
HGCOOKCJ_02664 4.4e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HGCOOKCJ_02665 1.4e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
HGCOOKCJ_02666 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HGCOOKCJ_02667 2.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HGCOOKCJ_02668 2.9e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGCOOKCJ_02669 1.9e-178 rbsR K transcriptional
HGCOOKCJ_02670 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HGCOOKCJ_02671 8.6e-70 pgsC S biosynthesis protein
HGCOOKCJ_02672 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HGCOOKCJ_02673 3.6e-21 ywtC
HGCOOKCJ_02674 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HGCOOKCJ_02675 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HGCOOKCJ_02676 8.4e-171 ywtF K Transcriptional regulator
HGCOOKCJ_02677 1.9e-248 ywtG EGP Major facilitator Superfamily
HGCOOKCJ_02678 7.6e-216 gerAC S Spore germination protein
HGCOOKCJ_02679 7.5e-200 gerBB E Spore germination protein
HGCOOKCJ_02680 3.5e-266 gerBA EG Spore germination protein
HGCOOKCJ_02681 7.1e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HGCOOKCJ_02682 7.2e-217 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HGCOOKCJ_02683 1.2e-260
HGCOOKCJ_02684 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HGCOOKCJ_02685 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HGCOOKCJ_02686 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HGCOOKCJ_02687 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
HGCOOKCJ_02688 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HGCOOKCJ_02689 1.1e-150 tagG GM Transport permease protein
HGCOOKCJ_02690 1.8e-279 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HGCOOKCJ_02691 1.6e-100 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HGCOOKCJ_02693 8.1e-257 ggaA M Glycosyltransferase like family 2
HGCOOKCJ_02694 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HGCOOKCJ_02695 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HGCOOKCJ_02696 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HGCOOKCJ_02697 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HGCOOKCJ_02698 6e-38
HGCOOKCJ_02699 0.0 lytB 3.5.1.28 D Stage II sporulation protein
HGCOOKCJ_02700 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HGCOOKCJ_02701 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HGCOOKCJ_02702 3.3e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HGCOOKCJ_02703 7.4e-222 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
HGCOOKCJ_02704 2.4e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HGCOOKCJ_02705 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
HGCOOKCJ_02706 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
HGCOOKCJ_02707 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
HGCOOKCJ_02708 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
HGCOOKCJ_02709 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HGCOOKCJ_02710 6e-163 yvhJ K Transcriptional regulator
HGCOOKCJ_02711 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HGCOOKCJ_02712 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HGCOOKCJ_02713 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGCOOKCJ_02714 7.3e-155 degV S protein conserved in bacteria
HGCOOKCJ_02715 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HGCOOKCJ_02716 5.7e-46 comFB S Late competence development protein ComFB
HGCOOKCJ_02717 2.7e-129 comFC S Phosphoribosyl transferase domain
HGCOOKCJ_02718 7e-74 yvyF S flagellar protein
HGCOOKCJ_02719 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
HGCOOKCJ_02720 2.4e-78 flgN NOU FlgN protein
HGCOOKCJ_02721 1.2e-264 flgK N flagellar hook-associated protein
HGCOOKCJ_02722 1.1e-156 flgL N Belongs to the bacterial flagellin family
HGCOOKCJ_02723 2.6e-50 yviE
HGCOOKCJ_02724 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HGCOOKCJ_02725 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HGCOOKCJ_02726 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HGCOOKCJ_02727 6.1e-57 flaG N flagellar protein FlaG
HGCOOKCJ_02728 1.3e-266 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HGCOOKCJ_02729 2.9e-69 fliS N flagellar protein FliS
HGCOOKCJ_02730 1.9e-08 fliT S bacterial-type flagellum organization
HGCOOKCJ_02731 2.8e-66
HGCOOKCJ_02732 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HGCOOKCJ_02733 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HGCOOKCJ_02734 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HGCOOKCJ_02735 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HGCOOKCJ_02736 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
HGCOOKCJ_02737 1.6e-123 ftsE D cell division ATP-binding protein FtsE
HGCOOKCJ_02738 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HGCOOKCJ_02739 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HGCOOKCJ_02740 5.3e-56 swrA S Swarming motility protein
HGCOOKCJ_02741 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HGCOOKCJ_02742 7.9e-228 yvkA EGP Major facilitator Superfamily
HGCOOKCJ_02743 7e-101 yvkB K Transcriptional regulator
HGCOOKCJ_02744 0.0 yvkC 2.7.9.2 GT Phosphotransferase
HGCOOKCJ_02745 1.2e-30 csbA S protein conserved in bacteria
HGCOOKCJ_02746 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HGCOOKCJ_02747 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HGCOOKCJ_02748 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HGCOOKCJ_02749 6.7e-34 yvkN
HGCOOKCJ_02750 8e-49 yvlA
HGCOOKCJ_02751 3.4e-168 yvlB S Putative adhesin
HGCOOKCJ_02752 2.6e-26 pspB KT PspC domain
HGCOOKCJ_02753 1.2e-50 yvlD S Membrane
HGCOOKCJ_02754 2.7e-203 yvmA EGP Major facilitator Superfamily
HGCOOKCJ_02755 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
HGCOOKCJ_02756 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
HGCOOKCJ_02757 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
HGCOOKCJ_02758 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
HGCOOKCJ_02759 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HGCOOKCJ_02760 3.6e-134 yvoA K transcriptional
HGCOOKCJ_02761 8.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HGCOOKCJ_02762 6.8e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HGCOOKCJ_02763 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HGCOOKCJ_02764 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HGCOOKCJ_02765 1.5e-164 yvoD P COG0370 Fe2 transport system protein B
HGCOOKCJ_02766 1.3e-119 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HGCOOKCJ_02767 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HGCOOKCJ_02768 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
HGCOOKCJ_02769 4.5e-140 yvpB NU protein conserved in bacteria
HGCOOKCJ_02770 4.8e-221 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HGCOOKCJ_02771 1.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HGCOOKCJ_02772 6.6e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HGCOOKCJ_02773 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HGCOOKCJ_02774 1.7e-116 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HGCOOKCJ_02775 3.1e-133 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HGCOOKCJ_02776 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HGCOOKCJ_02777 8e-114 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HGCOOKCJ_02778 4.6e-121
HGCOOKCJ_02779 0.0
HGCOOKCJ_02781 0.0 msbA2 3.6.3.44 V ABC transporter
HGCOOKCJ_02782 2.4e-278 S COG0457 FOG TPR repeat
HGCOOKCJ_02783 1.4e-102 usp CBM50 M protein conserved in bacteria
HGCOOKCJ_02784 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HGCOOKCJ_02785 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HGCOOKCJ_02786 5.7e-166 rapZ S Displays ATPase and GTPase activities
HGCOOKCJ_02787 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HGCOOKCJ_02788 1.4e-170 whiA K May be required for sporulation
HGCOOKCJ_02789 1.6e-36 crh G Phosphocarrier protein Chr
HGCOOKCJ_02790 8.6e-147 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HGCOOKCJ_02791 1.8e-33
HGCOOKCJ_02792 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGCOOKCJ_02793 2.3e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HGCOOKCJ_02794 5.6e-141 yvcR V ABC transporter, ATP-binding protein
HGCOOKCJ_02795 0.0 yxdM V ABC transporter (permease)
HGCOOKCJ_02796 1.3e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGCOOKCJ_02797 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HGCOOKCJ_02798 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
HGCOOKCJ_02799 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
HGCOOKCJ_02800 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
HGCOOKCJ_02801 3.6e-174 yvdE K Transcriptional regulator
HGCOOKCJ_02802 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
HGCOOKCJ_02803 1.3e-235 mdxE G COG2182 Maltose-binding periplasmic proteins domains
HGCOOKCJ_02804 5.3e-245 malC P COG1175 ABC-type sugar transport systems, permease components
HGCOOKCJ_02805 7.8e-149 malD P transport
HGCOOKCJ_02806 1.2e-158 malA S Protein of unknown function (DUF1189)
HGCOOKCJ_02807 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
HGCOOKCJ_02808 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HGCOOKCJ_02809 1.3e-122 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HGCOOKCJ_02810 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HGCOOKCJ_02812 1.5e-183 S Patatin-like phospholipase
HGCOOKCJ_02813 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
HGCOOKCJ_02814 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
HGCOOKCJ_02815 4.1e-50 sugE P Small Multidrug Resistance protein
HGCOOKCJ_02816 6.7e-51 ykkC P Small Multidrug Resistance protein
HGCOOKCJ_02817 2.6e-106 yvdT K Transcriptional regulator
HGCOOKCJ_02818 1.8e-295 yveA E amino acid
HGCOOKCJ_02819 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HGCOOKCJ_02820 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
HGCOOKCJ_02821 9.6e-266 pbpE V Beta-lactamase
HGCOOKCJ_02822 3.1e-127 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HGCOOKCJ_02823 1.3e-48 MA20_18690 S Protein of unknown function (DUF3237)
HGCOOKCJ_02824 4.6e-93 padC Q Phenolic acid decarboxylase
HGCOOKCJ_02826 4.8e-287 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HGCOOKCJ_02827 5.7e-77 slr K transcriptional
HGCOOKCJ_02828 4e-122 ywqC M biosynthesis protein
HGCOOKCJ_02829 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
HGCOOKCJ_02830 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
HGCOOKCJ_02831 2e-224 epsD GT4 M Glycosyl transferase 4-like
HGCOOKCJ_02832 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HGCOOKCJ_02833 5.3e-220 epsF GT4 M Glycosyl transferases group 1
HGCOOKCJ_02834 4.8e-207 epsG S EpsG family
HGCOOKCJ_02835 3.6e-196 epsH GT2 S Glycosyltransferase like family 2
HGCOOKCJ_02836 3.6e-207 epsI GM pyruvyl transferase
HGCOOKCJ_02837 1.9e-197 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HGCOOKCJ_02838 8.9e-260 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HGCOOKCJ_02839 2.6e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HGCOOKCJ_02840 2.2e-58 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
HGCOOKCJ_02841 1.2e-224 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HGCOOKCJ_02842 5.8e-188 yvfF GM Exopolysaccharide biosynthesis protein
HGCOOKCJ_02843 1e-31 yvfG S YvfG protein
HGCOOKCJ_02844 6.5e-243 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HGCOOKCJ_02845 1.4e-309 yvfH C L-lactate permease
HGCOOKCJ_02846 1e-112 yvfI K COG2186 Transcriptional regulators
HGCOOKCJ_02847 1.8e-184 lacR K Transcriptional regulator
HGCOOKCJ_02848 2.9e-232 cycB G COG2182 Maltose-binding periplasmic proteins domains
HGCOOKCJ_02849 1.3e-232 malC P COG1175 ABC-type sugar transport systems, permease components
HGCOOKCJ_02850 3.2e-150 ganQ P transport
HGCOOKCJ_02851 0.0 lacA 3.2.1.23 G beta-galactosidase
HGCOOKCJ_02852 2.6e-252 galA 3.2.1.89 G arabinogalactan
HGCOOKCJ_02853 1.4e-199 rsbU 3.1.3.3 T response regulator
HGCOOKCJ_02854 2.6e-157 rsbQ S Alpha/beta hydrolase family
HGCOOKCJ_02855 3e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
HGCOOKCJ_02856 6.2e-134 yvfS V COG0842 ABC-type multidrug transport system, permease component
HGCOOKCJ_02857 8.9e-201 desK 2.7.13.3 T Histidine kinase
HGCOOKCJ_02858 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGCOOKCJ_02859 1.5e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HGCOOKCJ_02860 1.2e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HGCOOKCJ_02861 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HGCOOKCJ_02862 4.3e-197 yvbX S Glycosyl hydrolase
HGCOOKCJ_02863 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HGCOOKCJ_02864 8.5e-157 yvbV EG EamA-like transporter family
HGCOOKCJ_02865 3.9e-159 yvbU K Transcriptional regulator
HGCOOKCJ_02866 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGCOOKCJ_02867 5.5e-203 araR K transcriptional
HGCOOKCJ_02868 1.6e-252 araE EGP Major facilitator Superfamily
HGCOOKCJ_02869 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HGCOOKCJ_02870 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HGCOOKCJ_02871 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HGCOOKCJ_02872 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HGCOOKCJ_02873 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HGCOOKCJ_02874 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HGCOOKCJ_02875 7.7e-82 yvbK 3.1.3.25 K acetyltransferase
HGCOOKCJ_02876 0.0 tcaA S response to antibiotic
HGCOOKCJ_02877 4.2e-124 exoY M Membrane
HGCOOKCJ_02878 8.6e-113 yvbH S YvbH-like oligomerisation region
HGCOOKCJ_02879 6.4e-103 yvbG U UPF0056 membrane protein
HGCOOKCJ_02880 1.4e-98 yvbF K Belongs to the GbsR family
HGCOOKCJ_02881 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HGCOOKCJ_02882 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HGCOOKCJ_02883 2.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HGCOOKCJ_02884 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HGCOOKCJ_02885 4.5e-45 sdpR K transcriptional
HGCOOKCJ_02886 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HGCOOKCJ_02887 4.4e-08
HGCOOKCJ_02888 7.6e-172
HGCOOKCJ_02889 7.9e-13 S Sporulation delaying protein SdpA
HGCOOKCJ_02890 8.7e-61 yvbF K Belongs to the GbsR family
HGCOOKCJ_02891 3e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HGCOOKCJ_02892 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HGCOOKCJ_02893 1.1e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HGCOOKCJ_02894 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HGCOOKCJ_02895 4.2e-226 NT chemotaxis protein
HGCOOKCJ_02896 2.2e-54 yodB K transcriptional
HGCOOKCJ_02897 8e-70 yvaO K Cro/C1-type HTH DNA-binding domain
HGCOOKCJ_02898 4e-69 K transcriptional
HGCOOKCJ_02899 7.5e-36 yvzC K Transcriptional
HGCOOKCJ_02900 3.7e-153 yvaM S Serine aminopeptidase, S33
HGCOOKCJ_02901 2.4e-23 secG U Preprotein translocase subunit SecG
HGCOOKCJ_02902 5.6e-143 est 3.1.1.1 S Carboxylesterase
HGCOOKCJ_02903 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HGCOOKCJ_02904 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HGCOOKCJ_02906 2.9e-132 S Phage integrase family
HGCOOKCJ_02907 3.5e-64
HGCOOKCJ_02910 7.2e-44 K Helix-turn-helix XRE-family like proteins
HGCOOKCJ_02911 4.7e-07 acoR T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HGCOOKCJ_02912 4.3e-10 K Helix-turn-helix XRE-family like proteins
HGCOOKCJ_02914 4.2e-70 L dnaD_dom DnaD domain protein
HGCOOKCJ_02915 4.5e-51 dnaC L DNA replication protein
HGCOOKCJ_02917 4.3e-08
HGCOOKCJ_02918 5.1e-32
HGCOOKCJ_02922 2e-07 yqaO S Phage-like element PBSX protein XtrA
HGCOOKCJ_02927 6.7e-45 S dUTPase
HGCOOKCJ_02928 1.4e-13 S YopX protein
HGCOOKCJ_02931 1.4e-51 wecC 1.1.1.336 M ArpU family transcriptional regulator
HGCOOKCJ_02932 8.3e-60 L Phage integrase family
HGCOOKCJ_02938 5.1e-28 L HNH endonuclease
HGCOOKCJ_02939 4.5e-17
HGCOOKCJ_02940 8.5e-150 S Phage Terminase
HGCOOKCJ_02941 4.3e-105 S Phage portal protein
HGCOOKCJ_02942 4.2e-48 S Caudovirus prohead serine protease
HGCOOKCJ_02943 1.2e-90 S Phage capsid family
HGCOOKCJ_02944 5.9e-11 S Phage gp6-like head-tail connector protein
HGCOOKCJ_02945 9.4e-08 S head-tail adaptor
HGCOOKCJ_02946 7.2e-15 S Bacteriophage HK97-gp10, putative tail-component
HGCOOKCJ_02947 1.9e-17
HGCOOKCJ_02948 4.6e-53 S phage major tail protein, phi13 family
HGCOOKCJ_02950 3.6e-149 D Phage-related minor tail protein
HGCOOKCJ_02951 3.9e-44 S Phage tail protein
HGCOOKCJ_02952 2e-104 mur1 NU Prophage endopeptidase tail
HGCOOKCJ_02953 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
HGCOOKCJ_02954 2.4e-102 S Domain of unknown function (DUF2479)
HGCOOKCJ_02956 1.1e-08 S Phage uncharacterised protein (Phage_XkdX)
HGCOOKCJ_02957 2.1e-57 S Bacteriophage holin family
HGCOOKCJ_02958 2e-113 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HGCOOKCJ_02961 3.6e-12
HGCOOKCJ_02962 1.4e-08
HGCOOKCJ_02963 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HGCOOKCJ_02964 4.1e-101 K Bacterial regulatory proteins, tetR family
HGCOOKCJ_02965 2.8e-55 yvaE P Small Multidrug Resistance protein
HGCOOKCJ_02966 5.7e-73 yvaD S Family of unknown function (DUF5360)
HGCOOKCJ_02967 0.0 yvaC S Fusaric acid resistance protein-like
HGCOOKCJ_02968 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HGCOOKCJ_02969 2.1e-199 yvaA 1.1.1.371 S Oxidoreductase
HGCOOKCJ_02970 2.2e-48 csoR S transcriptional
HGCOOKCJ_02971 1.5e-29 copZ P Copper resistance protein CopZ
HGCOOKCJ_02972 0.0 copA 3.6.3.54 P P-type ATPase
HGCOOKCJ_02973 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HGCOOKCJ_02974 1.6e-104 bdbD O Thioredoxin
HGCOOKCJ_02975 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
HGCOOKCJ_02976 4.1e-107 yvgT S membrane
HGCOOKCJ_02977 0.0 helD 3.6.4.12 L DNA helicase
HGCOOKCJ_02978 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HGCOOKCJ_02979 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HGCOOKCJ_02980 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HGCOOKCJ_02981 5.4e-86 yvgO
HGCOOKCJ_02982 9.1e-158 yvgN S reductase
HGCOOKCJ_02983 4.7e-120 modB P COG4149 ABC-type molybdate transport system, permease component
HGCOOKCJ_02984 5.8e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HGCOOKCJ_02985 8e-171 yvgK P COG1910 Periplasmic molybdate-binding protein domain
HGCOOKCJ_02986 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HGCOOKCJ_02987 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HGCOOKCJ_02988 6.5e-16 S Small spore protein J (Spore_SspJ)
HGCOOKCJ_02989 2.6e-237 yvsH E Arginine ornithine antiporter
HGCOOKCJ_02991 2.1e-179 fhuD P ABC transporter
HGCOOKCJ_02992 9.3e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGCOOKCJ_02993 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGCOOKCJ_02994 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
HGCOOKCJ_02995 1.1e-175 M Efflux transporter rnd family, mfp subunit
HGCOOKCJ_02996 7.1e-124 macB V ABC transporter, ATP-binding protein
HGCOOKCJ_02997 1.8e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
HGCOOKCJ_02998 1.3e-64 yvrL S Regulatory protein YrvL
HGCOOKCJ_02999 7.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
HGCOOKCJ_03000 2.4e-19 S YvrJ protein family
HGCOOKCJ_03001 1.8e-96 yvrI K RNA polymerase
HGCOOKCJ_03002 3.6e-22
HGCOOKCJ_03003 3.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGCOOKCJ_03004 0.0 T PhoQ Sensor
HGCOOKCJ_03005 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
HGCOOKCJ_03006 6.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HGCOOKCJ_03007 1.8e-170 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HGCOOKCJ_03008 7.7e-186 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGCOOKCJ_03009 2.8e-249 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HGCOOKCJ_03010 6.5e-102 yvqK 2.5.1.17 S Adenosyltransferase
HGCOOKCJ_03011 4.8e-227 yvqJ EGP Major facilitator Superfamily
HGCOOKCJ_03012 5.6e-62 liaI S membrane
HGCOOKCJ_03013 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HGCOOKCJ_03014 9.3e-129 liaG S Putative adhesin
HGCOOKCJ_03015 5.6e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HGCOOKCJ_03016 5.5e-187 vraS 2.7.13.3 T Histidine kinase
HGCOOKCJ_03017 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGCOOKCJ_03018 6e-189 gerAC S Spore germination B3/ GerAC like, C-terminal
HGCOOKCJ_03019 9.1e-198 gerAB E Spore germination protein
HGCOOKCJ_03020 3.7e-247 gerAA EG Spore germination protein
HGCOOKCJ_03021 2.3e-24 S Protein of unknown function (DUF3970)
HGCOOKCJ_03022 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HGCOOKCJ_03023 4.3e-158 yuxN K Transcriptional regulator
HGCOOKCJ_03024 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
HGCOOKCJ_03025 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGCOOKCJ_03026 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HGCOOKCJ_03027 1.2e-79 dps P Ferritin-like domain
HGCOOKCJ_03028 4.7e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HGCOOKCJ_03029 3.9e-34 pepF2 E COG1164 Oligoendopeptidase F
HGCOOKCJ_03030 6.3e-258 pepF2 E COG1164 Oligoendopeptidase F
HGCOOKCJ_03031 5.6e-66 S YusW-like protein
HGCOOKCJ_03032 1e-153 yusV 3.6.3.34 HP ABC transporter
HGCOOKCJ_03033 3.8e-47 yusU S Protein of unknown function (DUF2573)
HGCOOKCJ_03034 2.7e-160 yusT K LysR substrate binding domain
HGCOOKCJ_03035 2.5e-50 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HGCOOKCJ_03036 2.5e-62 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HGCOOKCJ_03037 8.4e-66 yusQ S Tautomerase enzyme
HGCOOKCJ_03038 3.8e-293 yusP P Major facilitator superfamily
HGCOOKCJ_03039 5.4e-75 yusO K Iron dependent repressor, N-terminal DNA binding domain
HGCOOKCJ_03040 3.2e-53 yusN M Coat F domain
HGCOOKCJ_03041 5.1e-40
HGCOOKCJ_03042 2.2e-165 fadM E Proline dehydrogenase
HGCOOKCJ_03043 4.7e-09 S YuzL-like protein
HGCOOKCJ_03044 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HGCOOKCJ_03045 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
HGCOOKCJ_03046 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HGCOOKCJ_03047 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
HGCOOKCJ_03048 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HGCOOKCJ_03049 1.1e-39 yusG S Protein of unknown function (DUF2553)
HGCOOKCJ_03050 3.3e-74 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
HGCOOKCJ_03051 5.6e-55 traF CO Thioredoxin
HGCOOKCJ_03052 2.4e-56 yusD S SCP-2 sterol transfer family
HGCOOKCJ_03053 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HGCOOKCJ_03054 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
HGCOOKCJ_03055 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
HGCOOKCJ_03056 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HGCOOKCJ_03057 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HGCOOKCJ_03058 1.4e-245 sufD O assembly protein SufD
HGCOOKCJ_03059 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HGCOOKCJ_03060 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HGCOOKCJ_03061 3.5e-271 sufB O FeS cluster assembly
HGCOOKCJ_03062 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGCOOKCJ_03063 1e-41
HGCOOKCJ_03065 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HGCOOKCJ_03066 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
HGCOOKCJ_03067 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HGCOOKCJ_03068 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HGCOOKCJ_03069 1.4e-156 yurN G Binding-protein-dependent transport system inner membrane component
HGCOOKCJ_03070 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
HGCOOKCJ_03071 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
HGCOOKCJ_03072 1.1e-135 yurK K UTRA
HGCOOKCJ_03073 1.2e-205 msmX P Belongs to the ABC transporter superfamily
HGCOOKCJ_03074 2.4e-169 bsn L Ribonuclease
HGCOOKCJ_03075 1.6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HGCOOKCJ_03076 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HGCOOKCJ_03078 1.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HGCOOKCJ_03079 3.6e-111 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HGCOOKCJ_03080 3.4e-152 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HGCOOKCJ_03081 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HGCOOKCJ_03082 7.9e-99 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HGCOOKCJ_03083 7.3e-61 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HGCOOKCJ_03084 6.6e-284 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HGCOOKCJ_03085 1.3e-224 pbuX F xanthine
HGCOOKCJ_03086 2.1e-236 pbuX F Permease family
HGCOOKCJ_03087 1.2e-302 pucR QT COG2508 Regulator of polyketide synthase expression
HGCOOKCJ_03088 1e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HGCOOKCJ_03089 3e-62 yunG
HGCOOKCJ_03090 4.3e-171 yunF S Protein of unknown function DUF72
HGCOOKCJ_03091 2e-141 yunE S membrane transporter protein
HGCOOKCJ_03092 5.8e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HGCOOKCJ_03093 4.8e-48 yunC S Domain of unknown function (DUF1805)
HGCOOKCJ_03094 8.4e-134 yunB S Sporulation protein YunB (Spo_YunB)
HGCOOKCJ_03095 4.5e-196 lytH M Peptidase, M23
HGCOOKCJ_03096 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HGCOOKCJ_03097 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HGCOOKCJ_03098 9.7e-48 yutD S protein conserved in bacteria
HGCOOKCJ_03099 1e-75 yutE S Protein of unknown function DUF86
HGCOOKCJ_03100 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HGCOOKCJ_03101 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HGCOOKCJ_03102 2e-199 yutH S Spore coat protein
HGCOOKCJ_03103 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
HGCOOKCJ_03104 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HGCOOKCJ_03105 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HGCOOKCJ_03106 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HGCOOKCJ_03107 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
HGCOOKCJ_03108 3.5e-57 yuzD S protein conserved in bacteria
HGCOOKCJ_03109 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
HGCOOKCJ_03110 3.2e-39 yuzB S Belongs to the UPF0349 family
HGCOOKCJ_03111 2.4e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HGCOOKCJ_03112 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HGCOOKCJ_03113 3.7e-63 erpA S Belongs to the HesB IscA family
HGCOOKCJ_03114 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGCOOKCJ_03115 9e-118 paiB K Putative FMN-binding domain
HGCOOKCJ_03116 4.9e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HGCOOKCJ_03118 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
HGCOOKCJ_03119 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
HGCOOKCJ_03120 8.4e-27 yuiB S Putative membrane protein
HGCOOKCJ_03121 5.6e-118 yuiC S protein conserved in bacteria
HGCOOKCJ_03122 1.2e-77 yuiD S protein conserved in bacteria
HGCOOKCJ_03123 1.5e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HGCOOKCJ_03124 3.9e-211 yuiF S antiporter
HGCOOKCJ_03125 1.1e-93 bioY S Biotin biosynthesis protein
HGCOOKCJ_03126 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
HGCOOKCJ_03127 1.3e-167 besA S Putative esterase
HGCOOKCJ_03128 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HGCOOKCJ_03129 2.3e-226 entC 5.4.4.2 HQ Isochorismate synthase
HGCOOKCJ_03130 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
HGCOOKCJ_03131 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
HGCOOKCJ_03132 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGCOOKCJ_03133 3.8e-36 mbtH S MbtH-like protein
HGCOOKCJ_03134 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
HGCOOKCJ_03135 1.2e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HGCOOKCJ_03136 6.5e-229 yukF QT Transcriptional regulator
HGCOOKCJ_03137 2.8e-45 esxA S Belongs to the WXG100 family
HGCOOKCJ_03138 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
HGCOOKCJ_03139 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
HGCOOKCJ_03140 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HGCOOKCJ_03141 0.0 esaA S type VII secretion protein EsaA
HGCOOKCJ_03142 6.6e-65 yueC S Family of unknown function (DUF5383)
HGCOOKCJ_03143 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGCOOKCJ_03144 4.8e-96 yueE S phosphohydrolase
HGCOOKCJ_03145 2.9e-24 S Protein of unknown function (DUF2642)
HGCOOKCJ_03146 6.1e-72 S Protein of unknown function (DUF2283)
HGCOOKCJ_03147 1.9e-190 yueF S transporter activity
HGCOOKCJ_03148 2.1e-32 yueG S Spore germination protein gerPA/gerPF
HGCOOKCJ_03149 7.4e-39 yueH S YueH-like protein
HGCOOKCJ_03150 1.6e-67 yueI S Protein of unknown function (DUF1694)
HGCOOKCJ_03151 2.9e-104 pncA Q COG1335 Amidases related to nicotinamidase
HGCOOKCJ_03152 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HGCOOKCJ_03153 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HGCOOKCJ_03154 1.1e-22 yuzC
HGCOOKCJ_03156 2.5e-162 comQ H Polyprenyl synthetase
HGCOOKCJ_03158 0.0 comP 2.7.13.3 T Histidine kinase
HGCOOKCJ_03159 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGCOOKCJ_03160 9.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
HGCOOKCJ_03161 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HGCOOKCJ_03162 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HGCOOKCJ_03163 4.8e-79 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HGCOOKCJ_03164 3.8e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HGCOOKCJ_03165 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HGCOOKCJ_03166 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HGCOOKCJ_03167 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HGCOOKCJ_03168 1.9e-14
HGCOOKCJ_03169 1.3e-233 maeN C COG3493 Na citrate symporter
HGCOOKCJ_03170 4.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
HGCOOKCJ_03171 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
HGCOOKCJ_03172 1.1e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HGCOOKCJ_03173 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HGCOOKCJ_03174 2.3e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
HGCOOKCJ_03175 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HGCOOKCJ_03176 6.3e-78 yufK S Family of unknown function (DUF5366)
HGCOOKCJ_03177 6.3e-75 yuxK S protein conserved in bacteria
HGCOOKCJ_03178 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HGCOOKCJ_03179 3.5e-186 yuxJ EGP Major facilitator Superfamily
HGCOOKCJ_03181 1.9e-115 kapD L the KinA pathway to sporulation
HGCOOKCJ_03182 2e-70 kapB G Kinase associated protein B
HGCOOKCJ_03183 4.6e-233 T PhoQ Sensor
HGCOOKCJ_03184 1.8e-228 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HGCOOKCJ_03185 9.8e-42 yugE S Domain of unknown function (DUF1871)
HGCOOKCJ_03186 1e-156 yugF I Hydrolase
HGCOOKCJ_03187 1.6e-85 alaR K Transcriptional regulator
HGCOOKCJ_03188 4.3e-200 yugH 2.6.1.1 E Aminotransferase
HGCOOKCJ_03189 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HGCOOKCJ_03190 1.1e-34 yuzA S Domain of unknown function (DUF378)
HGCOOKCJ_03191 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HGCOOKCJ_03192 2.8e-229 yugK C Dehydrogenase
HGCOOKCJ_03193 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
HGCOOKCJ_03195 1.3e-72 yugN S YugN-like family
HGCOOKCJ_03196 1.7e-182 yugO P COG1226 Kef-type K transport systems
HGCOOKCJ_03197 1.1e-53 mstX S Membrane-integrating protein Mistic
HGCOOKCJ_03198 4.6e-39
HGCOOKCJ_03199 1.4e-116 yugP S Zn-dependent protease
HGCOOKCJ_03200 2.6e-236 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HGCOOKCJ_03201 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HGCOOKCJ_03202 2.1e-72 yugU S Uncharacterised protein family UPF0047
HGCOOKCJ_03203 1e-35
HGCOOKCJ_03204 2.6e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HGCOOKCJ_03205 3.2e-225 mcpA NT chemotaxis protein
HGCOOKCJ_03206 1.5e-222 mcpA NT chemotaxis protein
HGCOOKCJ_03207 2.2e-295 mcpA NT chemotaxis protein
HGCOOKCJ_03208 5.1e-239 mcpA NT chemotaxis protein
HGCOOKCJ_03209 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
HGCOOKCJ_03210 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
HGCOOKCJ_03211 1.3e-281 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HGCOOKCJ_03212 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HGCOOKCJ_03213 1.4e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
HGCOOKCJ_03214 3.3e-183 ygjR S Oxidoreductase
HGCOOKCJ_03215 6.3e-197 yubA S transporter activity
HGCOOKCJ_03216 1.2e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HGCOOKCJ_03218 2.6e-88 cdoA 1.13.11.20 S Cysteine dioxygenase type I
HGCOOKCJ_03219 6.2e-277 yubD P Major Facilitator Superfamily
HGCOOKCJ_03220 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HGCOOKCJ_03221 1e-38 yiaA S yiaA/B two helix domain
HGCOOKCJ_03222 5.4e-237 ktrB P Potassium
HGCOOKCJ_03223 5e-122 ktrA P COG0569 K transport systems, NAD-binding component
HGCOOKCJ_03224 2.2e-91 yuaB
HGCOOKCJ_03225 1.1e-95 yuaC K Belongs to the GbsR family
HGCOOKCJ_03226 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HGCOOKCJ_03227 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
HGCOOKCJ_03228 7.9e-108 yuaD
HGCOOKCJ_03229 3.9e-84 yuaE S DinB superfamily
HGCOOKCJ_03230 1.4e-77 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HGCOOKCJ_03231 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
HGCOOKCJ_03232 3.4e-94 M1-753 M FR47-like protein
HGCOOKCJ_03233 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
HGCOOKCJ_03234 6.7e-167 ygxA S Nucleotidyltransferase-like
HGCOOKCJ_03235 1.5e-56 ygzB S UPF0295 protein
HGCOOKCJ_03236 4e-80 perR P Belongs to the Fur family
HGCOOKCJ_03237 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
HGCOOKCJ_03238 1.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HGCOOKCJ_03239 8.7e-180 ygaE S Membrane
HGCOOKCJ_03240 1.8e-301 ygaD V ABC transporter
HGCOOKCJ_03241 1.3e-104 ygaC J Belongs to the UPF0374 family
HGCOOKCJ_03242 1.5e-37 ygaB S YgaB-like protein
HGCOOKCJ_03243 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
HGCOOKCJ_03244 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGCOOKCJ_03245 6.9e-36 yfhS
HGCOOKCJ_03246 7.8e-212 mutY L A G-specific
HGCOOKCJ_03247 5.5e-186 yfhP S membrane-bound metal-dependent
HGCOOKCJ_03248 0.0 yfhO S Bacterial membrane protein YfhO
HGCOOKCJ_03249 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HGCOOKCJ_03250 6.7e-172 yfhM S Alpha beta hydrolase
HGCOOKCJ_03251 3.5e-51 yfhL S SdpI/YhfL protein family
HGCOOKCJ_03252 9.2e-92 batE T Bacterial SH3 domain homologues
HGCOOKCJ_03253 1.3e-44 yfhJ S WVELL protein
HGCOOKCJ_03254 6.2e-20 sspK S reproduction
HGCOOKCJ_03255 1.1e-209 yfhI EGP Major facilitator Superfamily
HGCOOKCJ_03257 9.7e-52 yfhH S Protein of unknown function (DUF1811)
HGCOOKCJ_03258 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
HGCOOKCJ_03259 4.9e-173 yfhF S nucleoside-diphosphate sugar epimerase
HGCOOKCJ_03261 2.1e-25 yfhD S YfhD-like protein
HGCOOKCJ_03262 3.9e-107 yfhC C nitroreductase
HGCOOKCJ_03263 1.8e-167 yfhB 5.3.3.17 S PhzF family
HGCOOKCJ_03264 5.2e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGCOOKCJ_03265 3.1e-176 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGCOOKCJ_03266 6.2e-182 yfiY P ABC transporter substrate-binding protein
HGCOOKCJ_03267 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HGCOOKCJ_03268 3.1e-81 yfiV K transcriptional
HGCOOKCJ_03269 8.7e-287 yfiU EGP Major facilitator Superfamily
HGCOOKCJ_03270 3.3e-100 yfiT S Belongs to the metal hydrolase YfiT family
HGCOOKCJ_03271 5.1e-221 yfiS EGP Major facilitator Superfamily
HGCOOKCJ_03272 2e-109 yfiR K Transcriptional regulator
HGCOOKCJ_03273 9e-198 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HGCOOKCJ_03274 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HGCOOKCJ_03275 8.3e-99 padR K transcriptional
HGCOOKCJ_03276 4.6e-208 V COG0842 ABC-type multidrug transport system, permease component
HGCOOKCJ_03277 9.8e-214 V ABC-2 family transporter protein
HGCOOKCJ_03278 6.2e-171 V ABC transporter, ATP-binding protein
HGCOOKCJ_03279 3.2e-113 KT LuxR family transcriptional regulator
HGCOOKCJ_03280 1.1e-214 yxjM T Histidine kinase
HGCOOKCJ_03282 2.5e-233 S Oxidoreductase
HGCOOKCJ_03283 8.4e-184 G Xylose isomerase
HGCOOKCJ_03284 1.8e-262 iolT EGP Major facilitator Superfamily
HGCOOKCJ_03285 1.5e-177 K AraC-like ligand binding domain
HGCOOKCJ_03286 5.7e-163 yfiE 1.13.11.2 S glyoxalase
HGCOOKCJ_03287 9.8e-65 mhqP S DoxX
HGCOOKCJ_03288 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HGCOOKCJ_03289 2.1e-310 yfiB3 V ABC transporter
HGCOOKCJ_03290 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HGCOOKCJ_03291 3.2e-141 glvR K Helix-turn-helix domain, rpiR family
HGCOOKCJ_03292 9.9e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HGCOOKCJ_03293 1.1e-44 yfjA S Belongs to the WXG100 family
HGCOOKCJ_03294 9.2e-191 yfjB
HGCOOKCJ_03295 4.1e-144 yfjC
HGCOOKCJ_03296 1.8e-101 yfjD S Family of unknown function (DUF5381)
HGCOOKCJ_03297 1.3e-80 S Family of unknown function (DUF5381)
HGCOOKCJ_03298 4e-56 yfjF S UPF0060 membrane protein
HGCOOKCJ_03299 1.2e-25 sspH S Belongs to the SspH family
HGCOOKCJ_03300 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HGCOOKCJ_03301 6.4e-257 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HGCOOKCJ_03302 2.9e-197 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HGCOOKCJ_03303 1e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HGCOOKCJ_03304 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HGCOOKCJ_03305 3e-29 yfjL
HGCOOKCJ_03306 3.9e-86 yfjM S Psort location Cytoplasmic, score
HGCOOKCJ_03307 5.1e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HGCOOKCJ_03308 1.6e-39 S YfzA-like protein
HGCOOKCJ_03309 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HGCOOKCJ_03310 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HGCOOKCJ_03311 1.7e-184 corA P Mediates influx of magnesium ions
HGCOOKCJ_03312 4.2e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HGCOOKCJ_03313 2.6e-154 pdaA G deacetylase
HGCOOKCJ_03314 1.1e-26 yfjT
HGCOOKCJ_03315 5.4e-222 yfkA S YfkB-like domain
HGCOOKCJ_03316 6e-149 yfkC M Mechanosensitive ion channel
HGCOOKCJ_03317 1.2e-146 yfkD S YfkD-like protein
HGCOOKCJ_03318 6.1e-183 cax P COG0387 Ca2 H antiporter
HGCOOKCJ_03319 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HGCOOKCJ_03320 5e-08
HGCOOKCJ_03321 9.7e-144 yihY S Belongs to the UPF0761 family
HGCOOKCJ_03322 8.4e-51 yfkI S gas vesicle protein
HGCOOKCJ_03323 2.2e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HGCOOKCJ_03324 2.1e-29 yfkK S Belongs to the UPF0435 family
HGCOOKCJ_03325 6.8e-207 ydiM EGP Major facilitator Superfamily
HGCOOKCJ_03326 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
HGCOOKCJ_03327 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HGCOOKCJ_03328 1.6e-125 yfkO C nitroreductase
HGCOOKCJ_03329 1.8e-133 treR K transcriptional
HGCOOKCJ_03330 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HGCOOKCJ_03331 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HGCOOKCJ_03332 1.5e-283 yfkQ EG Spore germination protein
HGCOOKCJ_03333 5.1e-207 yfkR S spore germination
HGCOOKCJ_03335 1.6e-194 E Spore germination protein
HGCOOKCJ_03336 3.2e-256 agcS_1 E Sodium alanine symporter
HGCOOKCJ_03337 6e-67 yhdN S Domain of unknown function (DUF1992)
HGCOOKCJ_03338 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HGCOOKCJ_03339 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HGCOOKCJ_03340 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
HGCOOKCJ_03341 2.4e-50 yflH S Protein of unknown function (DUF3243)
HGCOOKCJ_03342 4.1e-19 yflI
HGCOOKCJ_03343 4e-18 yflJ S Protein of unknown function (DUF2639)
HGCOOKCJ_03344 9e-124 yflK S protein conserved in bacteria
HGCOOKCJ_03345 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HGCOOKCJ_03346 1.3e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HGCOOKCJ_03347 5.5e-152 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HGCOOKCJ_03348 8.5e-227 citM C Citrate transporter
HGCOOKCJ_03350 3e-181 yflP S Tripartite tricarboxylate transporter family receptor
HGCOOKCJ_03351 8.9e-119 citT T response regulator
HGCOOKCJ_03352 1e-290 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HGCOOKCJ_03353 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
HGCOOKCJ_03354 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HGCOOKCJ_03355 7.6e-58 yflT S Heat induced stress protein YflT
HGCOOKCJ_03356 2.9e-24 S Protein of unknown function (DUF3212)
HGCOOKCJ_03357 3.4e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HGCOOKCJ_03358 4.3e-170 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGCOOKCJ_03359 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGCOOKCJ_03360 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
HGCOOKCJ_03361 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
HGCOOKCJ_03362 7.7e-214 G Major Facilitator Superfamily
HGCOOKCJ_03363 8.5e-190 yfmJ S N-terminal domain of oxidoreductase
HGCOOKCJ_03364 7.5e-82 yfmK 2.3.1.128 K acetyltransferase
HGCOOKCJ_03365 6.3e-202 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HGCOOKCJ_03366 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HGCOOKCJ_03367 1.5e-209 yfmO EGP Major facilitator Superfamily
HGCOOKCJ_03368 2.8e-70 yfmP K transcriptional
HGCOOKCJ_03369 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
HGCOOKCJ_03370 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HGCOOKCJ_03371 1.1e-113 yfmS NT chemotaxis protein
HGCOOKCJ_03372 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HGCOOKCJ_03373 1.3e-241 yfnA E amino acid
HGCOOKCJ_03374 7.8e-134 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HGCOOKCJ_03375 2e-206 fsr P COG0477 Permeases of the major facilitator superfamily
HGCOOKCJ_03376 3.5e-190 yfnD M Nucleotide-diphospho-sugar transferase
HGCOOKCJ_03377 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HGCOOKCJ_03378 3.8e-181 yfnF M Nucleotide-diphospho-sugar transferase
HGCOOKCJ_03379 1.9e-172 yfnG 4.2.1.45 M dehydratase
HGCOOKCJ_03380 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
HGCOOKCJ_03381 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HGCOOKCJ_03382 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HGCOOKCJ_03383 3.6e-199 yetN S Protein of unknown function (DUF3900)
HGCOOKCJ_03384 7.8e-213 yetM CH FAD binding domain
HGCOOKCJ_03385 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
HGCOOKCJ_03386 5.4e-159 yetK EG EamA-like transporter family
HGCOOKCJ_03387 5.3e-105 yetJ S Belongs to the BI1 family
HGCOOKCJ_03388 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
HGCOOKCJ_03389 4.4e-43 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HGCOOKCJ_03390 2.2e-89 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HGCOOKCJ_03391 2.2e-34
HGCOOKCJ_03392 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGCOOKCJ_03393 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HGCOOKCJ_03394 6.1e-123 yetF S membrane
HGCOOKCJ_03395 3.3e-258 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HGCOOKCJ_03396 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
HGCOOKCJ_03397 1.3e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HGCOOKCJ_03398 9.6e-291 lplA G Bacterial extracellular solute-binding protein
HGCOOKCJ_03399 0.0 yetA
HGCOOKCJ_03400 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
HGCOOKCJ_03401 3e-124 yesY E GDSL-like Lipase/Acylhydrolase
HGCOOKCJ_03402 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HGCOOKCJ_03403 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HGCOOKCJ_03404 1e-113 yesV S Protein of unknown function, DUF624
HGCOOKCJ_03405 8.9e-132 yesU S Domain of unknown function (DUF1961)
HGCOOKCJ_03406 3.8e-133 E GDSL-like Lipase/Acylhydrolase
HGCOOKCJ_03407 0.0 yesS K Transcriptional regulator
HGCOOKCJ_03408 1.6e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
HGCOOKCJ_03409 1.3e-165 yesQ P Binding-protein-dependent transport system inner membrane component
HGCOOKCJ_03410 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
HGCOOKCJ_03411 5e-248 yesO G Bacterial extracellular solute-binding protein
HGCOOKCJ_03412 2.9e-204 yesN K helix_turn_helix, arabinose operon control protein
HGCOOKCJ_03413 0.0 yesM 2.7.13.3 T Histidine kinase
HGCOOKCJ_03414 4.4e-104 yesL S Protein of unknown function, DUF624
HGCOOKCJ_03416 4.2e-103 yesJ K Acetyltransferase (GNAT) family
HGCOOKCJ_03417 5.2e-104 cotJC P Spore Coat
HGCOOKCJ_03418 1.5e-45 cotJB S CotJB protein
HGCOOKCJ_03419 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
HGCOOKCJ_03420 2.2e-159 yesF GM NAD(P)H-binding
HGCOOKCJ_03421 9.7e-82 yesE S SnoaL-like domain
HGCOOKCJ_03422 1.2e-103 dhaR3 K Transcriptional regulator
HGCOOKCJ_03424 9.4e-127 yeeN K transcriptional regulatory protein
HGCOOKCJ_03426 2.7e-213 S Tetratricopeptide repeat
HGCOOKCJ_03427 1.8e-192 3.4.24.40 CO amine dehydrogenase activity
HGCOOKCJ_03428 0.0 L nucleic acid phosphodiester bond hydrolysis
HGCOOKCJ_03429 5.5e-83 S Protein of unknown function, DUF600
HGCOOKCJ_03430 6.2e-31 S Colicin immunity protein / pyocin immunity protein
HGCOOKCJ_03432 1.2e-211 pstS P T5orf172
HGCOOKCJ_03433 0.0 yeeB L DEAD-like helicases superfamily
HGCOOKCJ_03434 0.0 yeeA V Type II restriction enzyme, methylase subunits
HGCOOKCJ_03435 3.2e-53 L Resolvase, N terminal domain
HGCOOKCJ_03436 3.2e-98 L Recombinase
HGCOOKCJ_03437 1.2e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HGCOOKCJ_03438 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HGCOOKCJ_03439 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HGCOOKCJ_03440 4e-156 yerO K Transcriptional regulator
HGCOOKCJ_03441 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HGCOOKCJ_03442 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HGCOOKCJ_03443 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HGCOOKCJ_03444 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HGCOOKCJ_03445 1.6e-123 sapB S MgtC SapB transporter
HGCOOKCJ_03446 1.1e-197 yerI S homoserine kinase type II (protein kinase fold)
HGCOOKCJ_03447 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
HGCOOKCJ_03448 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HGCOOKCJ_03449 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HGCOOKCJ_03450 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HGCOOKCJ_03452 3.2e-305 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HGCOOKCJ_03453 4.8e-51 yerC S protein conserved in bacteria
HGCOOKCJ_03454 3e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
HGCOOKCJ_03455 0.0 yerA 3.5.4.2 F adenine deaminase
HGCOOKCJ_03456 2.7e-27 S Protein of unknown function (DUF2892)
HGCOOKCJ_03457 2.3e-232 yjeH E Amino acid permease
HGCOOKCJ_03458 3.5e-73 K helix_turn_helix ASNC type
HGCOOKCJ_03459 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
HGCOOKCJ_03460 1.2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HGCOOKCJ_03461 1.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HGCOOKCJ_03462 7.6e-178 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HGCOOKCJ_03463 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HGCOOKCJ_03464 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGCOOKCJ_03465 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGCOOKCJ_03466 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGCOOKCJ_03467 1.2e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HGCOOKCJ_03468 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HGCOOKCJ_03469 7e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HGCOOKCJ_03470 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HGCOOKCJ_03471 8e-28 yebG S NETI protein
HGCOOKCJ_03472 4e-93 yebE S UPF0316 protein
HGCOOKCJ_03474 1.1e-118 yebC M Membrane
HGCOOKCJ_03475 6e-212 pbuG S permease
HGCOOKCJ_03476 3.7e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HGCOOKCJ_03477 0.0 yebA E COG1305 Transglutaminase-like enzymes
HGCOOKCJ_03478 9.5e-225 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HGCOOKCJ_03479 1.6e-177 yeaC S COG0714 MoxR-like ATPases
HGCOOKCJ_03480 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HGCOOKCJ_03481 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HGCOOKCJ_03482 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HGCOOKCJ_03483 2.4e-181 yeaA S Protein of unknown function (DUF4003)
HGCOOKCJ_03484 9.5e-160 ydjP I Alpha/beta hydrolase family
HGCOOKCJ_03485 1.4e-34 ydjO S Cold-inducible protein YdjO
HGCOOKCJ_03487 4.4e-157 ydjN U Involved in the tonB-independent uptake of proteins
HGCOOKCJ_03488 4.5e-64 ydjM M Lytic transglycolase
HGCOOKCJ_03489 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HGCOOKCJ_03490 2.7e-258 iolT EGP Major facilitator Superfamily
HGCOOKCJ_03491 4.7e-196 S Ion transport 2 domain protein
HGCOOKCJ_03492 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
HGCOOKCJ_03493 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HGCOOKCJ_03494 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HGCOOKCJ_03495 5.1e-114 pspA KT Phage shock protein A
HGCOOKCJ_03496 1.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HGCOOKCJ_03497 7.1e-256 gutA G MFS/sugar transport protein
HGCOOKCJ_03498 3.8e-201 gutB 1.1.1.14 E Dehydrogenase
HGCOOKCJ_03499 0.0 K NB-ARC domain
HGCOOKCJ_03500 1.1e-08 ydjC S Abhydrolase domain containing 18
HGCOOKCJ_03501 4.9e-257 J LlaJI restriction endonuclease
HGCOOKCJ_03502 1.2e-199 V AAA domain (dynein-related subfamily)
HGCOOKCJ_03504 1.6e-232 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HGCOOKCJ_03505 1.1e-250 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
HGCOOKCJ_03506 6.4e-66 KL Phage plasmid primase P4 family
HGCOOKCJ_03508 1.2e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HGCOOKCJ_03509 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HGCOOKCJ_03510 7.9e-129 ydiL S CAAX protease self-immunity
HGCOOKCJ_03511 2.9e-27 ydiK S Domain of unknown function (DUF4305)
HGCOOKCJ_03512 8.4e-126 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HGCOOKCJ_03513 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HGCOOKCJ_03514 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HGCOOKCJ_03515 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HGCOOKCJ_03516 0.0 ydiF S ABC transporter
HGCOOKCJ_03517 3.6e-188 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HGCOOKCJ_03518 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HGCOOKCJ_03519 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HGCOOKCJ_03520 9.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HGCOOKCJ_03521 4.6e-185 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HGCOOKCJ_03523 7.8e-08
HGCOOKCJ_03524 1.3e-63 hxlR K transcriptional
HGCOOKCJ_03525 3.3e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HGCOOKCJ_03526 4.6e-97 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HGCOOKCJ_03527 3e-187 tlpC 2.7.13.3 NT chemotaxis protein
HGCOOKCJ_03528 3.2e-72 nucA M Deoxyribonuclease NucA/NucB
HGCOOKCJ_03529 3.4e-70 nin S Competence protein J (ComJ)
HGCOOKCJ_03530 1.2e-298 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HGCOOKCJ_03531 3.5e-52 yckD S Protein of unknown function (DUF2680)
HGCOOKCJ_03532 3.3e-77 yckC S membrane
HGCOOKCJ_03535 1.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HGCOOKCJ_03536 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
HGCOOKCJ_03537 1.4e-228 yciC S GTPases (G3E family)
HGCOOKCJ_03538 5.5e-109 yciB M ErfK YbiS YcfS YnhG
HGCOOKCJ_03539 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
HGCOOKCJ_03540 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
HGCOOKCJ_03541 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
HGCOOKCJ_03542 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HGCOOKCJ_03543 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HGCOOKCJ_03544 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
HGCOOKCJ_03545 9.3e-283 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HGCOOKCJ_03546 1.3e-193 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HGCOOKCJ_03547 5.7e-163 I alpha/beta hydrolase fold
HGCOOKCJ_03548 1.2e-139 ycgR S permeases
HGCOOKCJ_03549 2.6e-147 ycgQ S membrane
HGCOOKCJ_03550 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
HGCOOKCJ_03551 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HGCOOKCJ_03552 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HGCOOKCJ_03553 5.1e-170 ycgM E Proline dehydrogenase
HGCOOKCJ_03554 2.9e-145 ycgL S Predicted nucleotidyltransferase
HGCOOKCJ_03555 2.9e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HGCOOKCJ_03556 2.2e-179 oxyR3 K LysR substrate binding domain
HGCOOKCJ_03557 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
HGCOOKCJ_03558 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HGCOOKCJ_03559 2.5e-109 tmrB S AAA domain
HGCOOKCJ_03560 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HGCOOKCJ_03561 2.4e-112 ycgI S Domain of unknown function (DUF1989)
HGCOOKCJ_03562 5.6e-250 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HGCOOKCJ_03563 1.2e-151 yqcI S YqcI/YcgG family
HGCOOKCJ_03564 6.8e-113 ycgF E Lysine exporter protein LysE YggA
HGCOOKCJ_03565 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
HGCOOKCJ_03566 6.2e-269 mdr EGP Major facilitator Superfamily
HGCOOKCJ_03567 6.5e-293 lctP C L-lactate permease
HGCOOKCJ_03568 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HGCOOKCJ_03569 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
HGCOOKCJ_03570 1.1e-98 ycgB
HGCOOKCJ_03571 8.7e-257 ycgA S Membrane
HGCOOKCJ_03572 1.2e-219 amhX S amidohydrolase
HGCOOKCJ_03573 5.3e-164 opuAC E glycine betaine
HGCOOKCJ_03574 1.3e-127 opuAB P glycine betaine
HGCOOKCJ_03575 5.1e-229 proV 3.6.3.32 E glycine betaine
HGCOOKCJ_03576 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
HGCOOKCJ_03577 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
HGCOOKCJ_03578 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
HGCOOKCJ_03579 2e-192 yceH P Belongs to the TelA family
HGCOOKCJ_03580 0.0 yceG S Putative component of 'biosynthetic module'
HGCOOKCJ_03581 6.3e-137 terC P Protein of unknown function (DUF475)
HGCOOKCJ_03582 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
HGCOOKCJ_03583 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
HGCOOKCJ_03584 3.9e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HGCOOKCJ_03585 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGCOOKCJ_03586 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HGCOOKCJ_03587 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HGCOOKCJ_03588 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
HGCOOKCJ_03589 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HGCOOKCJ_03590 1.6e-140 IQ Enoyl-(Acyl carrier protein) reductase
HGCOOKCJ_03591 5.5e-174 S response regulator aspartate phosphatase
HGCOOKCJ_03592 1.7e-95 cwlK M D-alanyl-D-alanine carboxypeptidase
HGCOOKCJ_03593 6.7e-268 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HGCOOKCJ_03594 5.9e-282 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HGCOOKCJ_03595 6.6e-177 ycdA S Domain of unknown function (DUF5105)
HGCOOKCJ_03596 1.6e-174 yccK C Aldo keto reductase
HGCOOKCJ_03597 4.5e-203 natB CP ABC-2 family transporter protein
HGCOOKCJ_03598 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
HGCOOKCJ_03599 1.2e-126 lytR_2 T LytTr DNA-binding domain
HGCOOKCJ_03600 2e-161 2.7.13.3 T GHKL domain
HGCOOKCJ_03601 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
HGCOOKCJ_03602 2e-59 S RDD family
HGCOOKCJ_03603 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HGCOOKCJ_03604 2.2e-202 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HGCOOKCJ_03605 4.8e-102 yxaF K Transcriptional regulator
HGCOOKCJ_03606 5.8e-229 lmrB EGP the major facilitator superfamily
HGCOOKCJ_03607 6.2e-210 ycbU E Selenocysteine lyase
HGCOOKCJ_03608 1.4e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HGCOOKCJ_03609 1.2e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HGCOOKCJ_03610 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HGCOOKCJ_03611 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HGCOOKCJ_03612 6.6e-136 ycbR T vWA found in TerF C terminus
HGCOOKCJ_03613 1.3e-78 sleB 3.5.1.28 M Cell wall
HGCOOKCJ_03614 8.2e-53 ycbP S Protein of unknown function (DUF2512)
HGCOOKCJ_03615 2.1e-115 S ABC-2 family transporter protein
HGCOOKCJ_03616 4.8e-168 ycbN V ABC transporter, ATP-binding protein
HGCOOKCJ_03617 2.4e-170 T PhoQ Sensor
HGCOOKCJ_03618 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGCOOKCJ_03619 7.3e-172 eamA1 EG spore germination
HGCOOKCJ_03620 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HGCOOKCJ_03621 1.8e-178 ycbJ S Macrolide 2'-phosphotransferase
HGCOOKCJ_03622 3.7e-298 garD 4.2.1.42, 4.2.1.7 G Altronate
HGCOOKCJ_03623 1.5e-124 ycbG K FCD
HGCOOKCJ_03624 2.2e-270 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HGCOOKCJ_03625 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
HGCOOKCJ_03626 3.7e-274 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HGCOOKCJ_03627 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
HGCOOKCJ_03628 9e-170 glnL T Regulator
HGCOOKCJ_03629 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
HGCOOKCJ_03630 1.5e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
HGCOOKCJ_03631 2.3e-257 agcS E Sodium alanine symporter
HGCOOKCJ_03632 9.3e-183 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
HGCOOKCJ_03633 6.7e-262 mmuP E amino acid
HGCOOKCJ_03634 5.4e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HGCOOKCJ_03636 4.9e-128 K UTRA
HGCOOKCJ_03637 2.1e-137 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HGCOOKCJ_03638 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HGCOOKCJ_03639 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HGCOOKCJ_03640 3.9e-192 yceA S Belongs to the UPF0176 family
HGCOOKCJ_03641 6.7e-167 ybfP K Transcriptional regulator
HGCOOKCJ_03642 4.3e-258 S Erythromycin esterase
HGCOOKCJ_03643 3.2e-46 ybfN
HGCOOKCJ_03644 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HGCOOKCJ_03645 2.7e-85 ybfM S SNARE associated Golgi protein
HGCOOKCJ_03646 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HGCOOKCJ_03647 2.5e-169 S Alpha/beta hydrolase family
HGCOOKCJ_03649 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
HGCOOKCJ_03650 1.9e-214 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HGCOOKCJ_03651 2.3e-145 msmR K AraC-like ligand binding domain
HGCOOKCJ_03652 8.8e-162 ybfH EG EamA-like transporter family
HGCOOKCJ_03653 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
HGCOOKCJ_03655 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
HGCOOKCJ_03656 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
HGCOOKCJ_03657 2.9e-35 S Protein of unknown function (DUF2651)
HGCOOKCJ_03658 7.3e-258 glpT G -transporter
HGCOOKCJ_03659 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HGCOOKCJ_03660 1.8e-290 ybeC E amino acid
HGCOOKCJ_03661 4.9e-41 ybyB
HGCOOKCJ_03662 1.4e-247 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HGCOOKCJ_03663 2.1e-151 ybxI 3.5.2.6 V beta-lactamase
HGCOOKCJ_03664 4.9e-30 ybxH S Family of unknown function (DUF5370)
HGCOOKCJ_03665 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
HGCOOKCJ_03666 2.4e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HGCOOKCJ_03667 1.5e-217 ybdO S Domain of unknown function (DUF4885)
HGCOOKCJ_03668 4.8e-154 ybdN
HGCOOKCJ_03669 1.6e-140 KLT Protein tyrosine kinase
HGCOOKCJ_03671 1.8e-173 T His Kinase A (phospho-acceptor) domain
HGCOOKCJ_03672 1.5e-123 T Transcriptional regulatory protein, C terminal
HGCOOKCJ_03673 6.2e-182 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HGCOOKCJ_03674 9.6e-79 txn CO Thioredoxin-like
HGCOOKCJ_03675 7.8e-91 C HEAT repeats
HGCOOKCJ_03676 4e-248 skfF S ABC transporter
HGCOOKCJ_03677 1.9e-135 skfE V ABC transporter
HGCOOKCJ_03678 1.6e-277 V CAAX protease self-immunity
HGCOOKCJ_03679 9.1e-239 J 4Fe-4S single cluster domain
HGCOOKCJ_03681 2e-203 ybcL EGP Major facilitator Superfamily
HGCOOKCJ_03682 5.1e-50 ybzH K Helix-turn-helix domain
HGCOOKCJ_03683 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
HGCOOKCJ_03684 3.9e-47
HGCOOKCJ_03685 3.7e-96 can 4.2.1.1 P carbonic anhydrase
HGCOOKCJ_03686 0.0 ybcC S Belongs to the UPF0753 family
HGCOOKCJ_03687 1.5e-278 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HGCOOKCJ_03688 5.1e-101 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HGCOOKCJ_03689 1.4e-121 adaA 3.2.2.21 K Transcriptional regulator
HGCOOKCJ_03690 2.1e-176 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HGCOOKCJ_03691 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HGCOOKCJ_03692 9.3e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HGCOOKCJ_03693 3e-225 ybbR S protein conserved in bacteria
HGCOOKCJ_03694 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HGCOOKCJ_03695 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HGCOOKCJ_03696 8.5e-99 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HGCOOKCJ_03702 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HGCOOKCJ_03703 6.4e-87 ybbJ J acetyltransferase
HGCOOKCJ_03704 2.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HGCOOKCJ_03705 1.1e-150 ybbH K transcriptional
HGCOOKCJ_03706 9.8e-234 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HGCOOKCJ_03707 4e-256 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HGCOOKCJ_03708 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HGCOOKCJ_03709 4.4e-241 ybbC 3.2.1.52 S protein conserved in bacteria
HGCOOKCJ_03710 5.4e-308 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HGCOOKCJ_03711 7.2e-167 feuA P Iron-uptake system-binding protein
HGCOOKCJ_03712 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGCOOKCJ_03713 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGCOOKCJ_03714 2.2e-142 ybbA S Putative esterase
HGCOOKCJ_03715 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
HGCOOKCJ_03717 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HGCOOKCJ_03718 7.2e-250 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGCOOKCJ_03719 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HGCOOKCJ_03720 5.7e-140 srfAD Q thioesterase
HGCOOKCJ_03721 4.2e-228 EGP Major Facilitator Superfamily
HGCOOKCJ_03722 4.9e-91 S YcxB-like protein
HGCOOKCJ_03723 7.4e-164 ycxC EG EamA-like transporter family
HGCOOKCJ_03724 4.4e-255 ycxD K GntR family transcriptional regulator
HGCOOKCJ_03725 5.5e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HGCOOKCJ_03726 4.4e-115 yczE S membrane
HGCOOKCJ_03727 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HGCOOKCJ_03728 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
HGCOOKCJ_03729 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HGCOOKCJ_03730 4.9e-162 bsdA K LysR substrate binding domain
HGCOOKCJ_03731 2e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HGCOOKCJ_03732 1.8e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HGCOOKCJ_03733 4e-39 bsdD 4.1.1.61 S response to toxic substance
HGCOOKCJ_03734 1.1e-83 yclD
HGCOOKCJ_03735 6.2e-162 yclE 3.4.11.5 S Alpha beta hydrolase
HGCOOKCJ_03736 1.5e-267 dtpT E amino acid peptide transporter
HGCOOKCJ_03737 2.9e-310 yclG M Pectate lyase superfamily protein
HGCOOKCJ_03739 6.8e-282 gerKA EG Spore germination protein
HGCOOKCJ_03740 1.3e-232 gerKC S spore germination
HGCOOKCJ_03741 9.9e-200 gerKB F Spore germination protein
HGCOOKCJ_03742 3.9e-122 yclH P ABC transporter
HGCOOKCJ_03743 1.7e-204 yclI V ABC transporter (permease) YclI
HGCOOKCJ_03744 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGCOOKCJ_03745 1.8e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HGCOOKCJ_03746 5.2e-71 S aspartate phosphatase
HGCOOKCJ_03749 7.5e-242 lysC 2.7.2.4 E Belongs to the aspartokinase family
HGCOOKCJ_03750 1.6e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGCOOKCJ_03751 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGCOOKCJ_03752 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HGCOOKCJ_03753 5.5e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HGCOOKCJ_03754 1.4e-251 ycnB EGP Major facilitator Superfamily
HGCOOKCJ_03755 6.5e-154 ycnC K Transcriptional regulator
HGCOOKCJ_03756 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
HGCOOKCJ_03757 1.6e-45 ycnE S Monooxygenase
HGCOOKCJ_03758 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HGCOOKCJ_03759 1.3e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HGCOOKCJ_03760 4.4e-247 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HGCOOKCJ_03761 3.4e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HGCOOKCJ_03762 6.1e-149 glcU U Glucose uptake
HGCOOKCJ_03763 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGCOOKCJ_03764 1.3e-100 ycnI S protein conserved in bacteria
HGCOOKCJ_03765 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
HGCOOKCJ_03766 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HGCOOKCJ_03767 7.3e-56
HGCOOKCJ_03768 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HGCOOKCJ_03769 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HGCOOKCJ_03770 7.3e-211 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HGCOOKCJ_03771 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HGCOOKCJ_03772 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HGCOOKCJ_03773 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HGCOOKCJ_03774 5e-113 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
HGCOOKCJ_03775 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HGCOOKCJ_03777 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HGCOOKCJ_03778 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
HGCOOKCJ_03779 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HGCOOKCJ_03780 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
HGCOOKCJ_03781 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HGCOOKCJ_03782 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HGCOOKCJ_03783 1.2e-132 kipR K Transcriptional regulator
HGCOOKCJ_03784 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
HGCOOKCJ_03786 1.4e-49 yczJ S biosynthesis
HGCOOKCJ_03787 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HGCOOKCJ_03788 2.8e-176 ydhF S Oxidoreductase
HGCOOKCJ_03789 0.0 mtlR K transcriptional regulator, MtlR
HGCOOKCJ_03790 1.4e-294 ydaB IQ acyl-CoA ligase
HGCOOKCJ_03791 1.1e-99 ydaC Q Methyltransferase domain
HGCOOKCJ_03792 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGCOOKCJ_03793 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HGCOOKCJ_03794 5e-104 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HGCOOKCJ_03795 6.8e-77 ydaG 1.4.3.5 S general stress protein
HGCOOKCJ_03796 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HGCOOKCJ_03797 5.1e-47 ydzA EGP Major facilitator Superfamily
HGCOOKCJ_03798 2.5e-74 lrpC K Transcriptional regulator
HGCOOKCJ_03799 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HGCOOKCJ_03800 1.9e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HGCOOKCJ_03801 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
HGCOOKCJ_03802 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HGCOOKCJ_03803 4.5e-233 ydaM M Glycosyl transferase family group 2
HGCOOKCJ_03804 0.0 ydaN S Bacterial cellulose synthase subunit
HGCOOKCJ_03805 0.0 ydaO E amino acid
HGCOOKCJ_03806 4.6e-79 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HGCOOKCJ_03807 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HGCOOKCJ_03808 9.4e-40
HGCOOKCJ_03809 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
HGCOOKCJ_03811 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
HGCOOKCJ_03812 3.8e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HGCOOKCJ_03814 8.9e-59 ydbB G Cupin domain
HGCOOKCJ_03815 2.8e-63 ydbC S Domain of unknown function (DUF4937
HGCOOKCJ_03816 3.2e-155 ydbD P Catalase
HGCOOKCJ_03817 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HGCOOKCJ_03818 2.5e-297 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HGCOOKCJ_03819 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
HGCOOKCJ_03820 6.3e-227 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HGCOOKCJ_03821 4.4e-181 ydbI S AI-2E family transporter
HGCOOKCJ_03822 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
HGCOOKCJ_03823 5.5e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HGCOOKCJ_03824 2.7e-52 ydbL
HGCOOKCJ_03825 3e-220 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HGCOOKCJ_03826 1.1e-18 S Fur-regulated basic protein B
HGCOOKCJ_03827 2.2e-07 S Fur-regulated basic protein A
HGCOOKCJ_03828 1.9e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HGCOOKCJ_03829 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HGCOOKCJ_03830 4.6e-202 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HGCOOKCJ_03831 1.9e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HGCOOKCJ_03832 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HGCOOKCJ_03833 2.1e-82 ydbS S Bacterial PH domain
HGCOOKCJ_03834 2.2e-263 ydbT S Membrane
HGCOOKCJ_03835 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HGCOOKCJ_03836 2.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HGCOOKCJ_03837 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HGCOOKCJ_03838 2.3e-223 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HGCOOKCJ_03839 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HGCOOKCJ_03840 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HGCOOKCJ_03841 1.3e-143 rsbR T Positive regulator of sigma-B
HGCOOKCJ_03842 5.2e-57 rsbS T antagonist
HGCOOKCJ_03843 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HGCOOKCJ_03844 7.1e-189 rsbU 3.1.3.3 KT phosphatase
HGCOOKCJ_03845 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
HGCOOKCJ_03846 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HGCOOKCJ_03847 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGCOOKCJ_03848 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HGCOOKCJ_03852 1.5e-82 ydcG S EVE domain
HGCOOKCJ_03853 1.6e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
HGCOOKCJ_03854 0.0 yhgF K COG2183 Transcriptional accessory protein
HGCOOKCJ_03855 1.6e-84 ydcK S Belongs to the SprT family
HGCOOKCJ_03863 2.7e-188 luxA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGCOOKCJ_03864 2.4e-71 lrpA K transcriptional
HGCOOKCJ_03865 3.9e-78 lrpB K transcriptional
HGCOOKCJ_03866 9.6e-100 yddQ 3.5.1.19 Q Isochorismatase family
HGCOOKCJ_03867 1.5e-143 yddR S Zn-dependent hydrolases of the beta-lactamase fold
HGCOOKCJ_03868 5e-227 ydeG EGP Major facilitator Superfamily
HGCOOKCJ_03872 2.1e-193 xerH A Belongs to the 'phage' integrase family
HGCOOKCJ_03873 6.3e-70
HGCOOKCJ_03874 2.5e-86
HGCOOKCJ_03875 2.5e-10 xkdX
HGCOOKCJ_03876 8.1e-07
HGCOOKCJ_03877 1.1e-172
HGCOOKCJ_03878 1e-57
HGCOOKCJ_03881 1.6e-90
HGCOOKCJ_03882 8.1e-131
HGCOOKCJ_03883 2.6e-91
HGCOOKCJ_03884 1.4e-121
HGCOOKCJ_03886 1.1e-68
HGCOOKCJ_03887 5.1e-81
HGCOOKCJ_03888 5.7e-186
HGCOOKCJ_03889 1.6e-94
HGCOOKCJ_03890 2.1e-266
HGCOOKCJ_03891 6.3e-282
HGCOOKCJ_03892 0.0 gp17a S Terminase-like family
HGCOOKCJ_03893 2e-158
HGCOOKCJ_03896 2.6e-230
HGCOOKCJ_03898 1.8e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HGCOOKCJ_03899 0.0
HGCOOKCJ_03902 5.7e-55 bldD K domain, Protein
HGCOOKCJ_03903 4e-17
HGCOOKCJ_03905 5.9e-238
HGCOOKCJ_03907 1.4e-256
HGCOOKCJ_03908 4.6e-35 K Cro/C1-type HTH DNA-binding domain
HGCOOKCJ_03909 3.8e-259
HGCOOKCJ_03910 1.1e-07 ywlA S Uncharacterised protein family (UPF0715)
HGCOOKCJ_03915 1.1e-96 S Super-infection exclusion protein B
HGCOOKCJ_03916 1.2e-86
HGCOOKCJ_03918 6.6e-106
HGCOOKCJ_03923 6.8e-198 L Belongs to the 'phage' integrase family
HGCOOKCJ_03924 6e-263 S DNA-sulfur modification-associated
HGCOOKCJ_03925 2.1e-177
HGCOOKCJ_03926 1.1e-33 K Transcriptional regulator
HGCOOKCJ_03937 6.2e-137 kilA S Phage regulatory protein Rha (Phage_pRha)
HGCOOKCJ_03938 8.8e-12 S Protein of unknown function (DUF2815)
HGCOOKCJ_03941 3e-78 yoqH M LysM domain
HGCOOKCJ_03943 1.5e-97 S Protein of unknown function (DUF1273)
HGCOOKCJ_03945 1e-44
HGCOOKCJ_03952 2.3e-77
HGCOOKCJ_03953 2.4e-155 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
HGCOOKCJ_03954 1e-130 yoqW S Belongs to the SOS response-associated peptidase family
HGCOOKCJ_03957 7.7e-149 S Pfam:DUF867
HGCOOKCJ_03958 0.0 M Parallel beta-helix repeats
HGCOOKCJ_03963 1.3e-170
HGCOOKCJ_03964 7.6e-180 L AAA domain
HGCOOKCJ_03965 1.4e-86
HGCOOKCJ_03966 3.6e-285 3.6.4.12 J DnaB-like helicase C terminal domain
HGCOOKCJ_03967 1.2e-224 L DNA primase activity
HGCOOKCJ_03968 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HGCOOKCJ_03969 0.0 2.7.7.7 L DNA polymerase
HGCOOKCJ_03970 9.9e-115 DR0488 S protein conserved in bacteria
HGCOOKCJ_03975 5.9e-88 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
HGCOOKCJ_03976 1.2e-96 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
HGCOOKCJ_03978 1.5e-255 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
HGCOOKCJ_03995 5.1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HGCOOKCJ_03996 2.3e-117 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGCOOKCJ_03997 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGCOOKCJ_03998 1e-107 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGCOOKCJ_03999 3.3e-97 L HNH endonuclease
HGCOOKCJ_04000 2.8e-66 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGCOOKCJ_04001 6.1e-38 O Glutaredoxin
HGCOOKCJ_04002 2.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HGCOOKCJ_04003 8.9e-83 yosT L Bacterial transcription activator, effector binding domain
HGCOOKCJ_04007 3.1e-38 S Protein of unknown function (DUF1643)
HGCOOKCJ_04008 3.7e-159 S Thymidylate synthase
HGCOOKCJ_04010 5.5e-30 sspB S spore protein
HGCOOKCJ_04011 1.9e-168 S Calcineurin-like phosphoesterase
HGCOOKCJ_04019 1.4e-10 K Cro/C1-type HTH DNA-binding domain
HGCOOKCJ_04020 3.6e-108 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HGCOOKCJ_04022 2.7e-307 yokA L Recombinase
HGCOOKCJ_04023 1.6e-107
HGCOOKCJ_04024 8.9e-95
HGCOOKCJ_04027 8.4e-156 aacC 2.3.1.81 V aminoglycoside
HGCOOKCJ_04028 1.1e-83 S Bacterial PH domain
HGCOOKCJ_04029 3.3e-113 yokF 3.1.31.1 L RNA catabolic process
HGCOOKCJ_04030 4.1e-203
HGCOOKCJ_04031 6.7e-92 yokH G SMI1 / KNR4 family
HGCOOKCJ_04032 1.2e-302 UW nuclease activity
HGCOOKCJ_04033 1.9e-94 yokJ S SMI1 / KNR4 family (SUKH-1)
HGCOOKCJ_04034 3.2e-109 yokK S SMI1 / KNR4 family
HGCOOKCJ_04035 2.8e-99 J Acetyltransferase (GNAT) domain
HGCOOKCJ_04037 6.8e-09 S Domain of unknown function (DUF4879)
HGCOOKCJ_04039 1.3e-37
HGCOOKCJ_04040 5.8e-55 S YolD-like protein
HGCOOKCJ_04041 1.9e-239 S impB/mucB/samB family C-terminal domain
HGCOOKCJ_04044 0.0 V Peptidase C39 family
HGCOOKCJ_04045 1.2e-70 CO cell redox homeostasis
HGCOOKCJ_04046 4.1e-242 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HGCOOKCJ_04047 3.4e-74 O protein disulfide oxidoreductase activity
HGCOOKCJ_04048 5.5e-40 S SPP1 phage holin
HGCOOKCJ_04049 4.4e-32 bhlA S BhlA holin family
HGCOOKCJ_04050 1.6e-186 3.5.1.28 M Ami_2
HGCOOKCJ_04052 6.5e-164
HGCOOKCJ_04053 0.0 G Exopolysaccharide biosynthesis protein
HGCOOKCJ_04054 6.4e-115
HGCOOKCJ_04055 0.0 S Pfam Transposase IS66
HGCOOKCJ_04056 6.2e-145 S Phage tail protein
HGCOOKCJ_04057 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HGCOOKCJ_04058 9.3e-116
HGCOOKCJ_04062 4.4e-10 thyX 2.1.1.148 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
HGCOOKCJ_04064 1.8e-46 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HGCOOKCJ_04067 6.1e-07 yfbR S HD containing hydrolase-like enzyme
HGCOOKCJ_04069 2.3e-17 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
HGCOOKCJ_04070 1.9e-15 K Transcriptional regulator
HGCOOKCJ_04071 1.4e-86 S exonuclease activity
HGCOOKCJ_04073 1e-89 S DNA primase activity
HGCOOKCJ_04074 3e-109 S DNA helicase activity
HGCOOKCJ_04075 7.8e-16
HGCOOKCJ_04076 2.3e-36
HGCOOKCJ_04078 1e-39
HGCOOKCJ_04080 3.4e-10 fld C flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
HGCOOKCJ_04081 1.2e-103 S Ribonucleotide reductase, small chain
HGCOOKCJ_04082 1.5e-277 S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
HGCOOKCJ_04083 1.9e-64 S AAA domain
HGCOOKCJ_04086 8.2e-48 F Nucleoside 2-deoxyribosyltransferase
HGCOOKCJ_04087 2.5e-34
HGCOOKCJ_04089 4.5e-07
HGCOOKCJ_04090 2.3e-32 yxcD S Protein of unknown function (DUF2653)
HGCOOKCJ_04092 6.2e-20
HGCOOKCJ_04093 2e-41 XK27_03185 S Phosphoribosyl-ATP pyrophosphohydrolase
HGCOOKCJ_04096 1.3e-52
HGCOOKCJ_04097 1.3e-69 L Phage integrase family
HGCOOKCJ_04099 3.9e-21 yocH 3.5.1.28 M 3D domain
HGCOOKCJ_04100 4.2e-69 lig 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP dependent DNA ligase domain
HGCOOKCJ_04102 9.1e-81
HGCOOKCJ_04105 8.1e-29 S Phage terminase, small subunit
HGCOOKCJ_04108 1.1e-210 S Phage Terminase
HGCOOKCJ_04109 7.1e-107 S Phage portal protein
HGCOOKCJ_04110 1.5e-55 S Caudovirus prohead serine protease
HGCOOKCJ_04111 6.8e-87 S Phage capsid family
HGCOOKCJ_04113 1.4e-21 S DNA packaging
HGCOOKCJ_04114 1.8e-11 S Phage head-tail joining protein
HGCOOKCJ_04115 7.4e-14 S Bacteriophage HK97-gp10, putative tail-component
HGCOOKCJ_04116 1.9e-07
HGCOOKCJ_04117 1.6e-40 S Phage tail tube protein
HGCOOKCJ_04119 1.5e-173 D Phage tail tape measure protein
HGCOOKCJ_04120 6.7e-176 S Phage tail protein
HGCOOKCJ_04121 2.4e-147 S Phage minor structural protein
HGCOOKCJ_04122 4e-23
HGCOOKCJ_04123 5.4e-77 S N-acetylmuramoyl-L-alanine amidase activity
HGCOOKCJ_04124 5.1e-12
HGCOOKCJ_04127 1.5e-09 S SPP1 phage holin
HGCOOKCJ_04128 8e-108 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 CBM50 M Glycosyl hydrolases family 25
HGCOOKCJ_04129 1.2e-97 S Phage integrase family
HGCOOKCJ_04130 2.1e-174 A Pre-toxin TG
HGCOOKCJ_04131 1.5e-63 S Immunity protein 70
HGCOOKCJ_04133 4.6e-61
HGCOOKCJ_04134 1.5e-20 L COG3666 Transposase and inactivated derivatives
HGCOOKCJ_04135 1.1e-106
HGCOOKCJ_04136 1e-24 S Domain of unknown function (DUF4935)
HGCOOKCJ_04138 5.4e-13 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HGCOOKCJ_04145 1.5e-57 traC L Domain of unknown function (DUF1738)
HGCOOKCJ_04146 3.5e-147 S DNA gyrase/topoisomerase IV, subunit A
HGCOOKCJ_04147 4.5e-184 S DNA gyrase B
HGCOOKCJ_04148 4e-15 repA S Replication initiator protein A (RepA) N-terminus
HGCOOKCJ_04150 1.2e-10 tdk 2.7.1.21 F Psort location Cytoplasmic, score
HGCOOKCJ_04155 4.3e-18 S Endodeoxyribonuclease RusA
HGCOOKCJ_04156 2.8e-22 2.7.4.8 F Guanylate kinase homologues.
HGCOOKCJ_04160 9.8e-180 S Bacterial DNA polymerase III alpha subunit
HGCOOKCJ_04162 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HGCOOKCJ_04163 8.7e-30 cspL K Cold shock
HGCOOKCJ_04164 6.1e-79 carD K Transcription factor
HGCOOKCJ_04165 4.6e-35 ydzE EG spore germination
HGCOOKCJ_04166 1.1e-166 rhaS5 K AraC-like ligand binding domain
HGCOOKCJ_04167 2.3e-173 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HGCOOKCJ_04168 2.5e-166 ydeE K AraC family transcriptional regulator
HGCOOKCJ_04169 2.2e-265 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HGCOOKCJ_04170 3.4e-220 ydeG EGP Major facilitator superfamily
HGCOOKCJ_04171 2.9e-47 ydeH
HGCOOKCJ_04172 8.9e-107 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
HGCOOKCJ_04173 4e-116
HGCOOKCJ_04174 1.8e-153 ydeK EG -transporter
HGCOOKCJ_04175 1.5e-274 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HGCOOKCJ_04176 4.2e-74 maoC I N-terminal half of MaoC dehydratase
HGCOOKCJ_04177 8.6e-107 ydeN S Serine hydrolase
HGCOOKCJ_04178 1.1e-58 K HxlR-like helix-turn-helix
HGCOOKCJ_04179 1.9e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HGCOOKCJ_04180 4.8e-69 ydeP K Transcriptional regulator
HGCOOKCJ_04181 1.6e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
HGCOOKCJ_04182 1.2e-195 ydeR EGP Major facilitator Superfamily
HGCOOKCJ_04183 8.4e-105 ydeS K Transcriptional regulator
HGCOOKCJ_04184 1.3e-57 arsR K transcriptional
HGCOOKCJ_04185 5.2e-232 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HGCOOKCJ_04186 7.2e-149 ydfB J GNAT acetyltransferase
HGCOOKCJ_04187 1e-162 ydfC EG EamA-like transporter family
HGCOOKCJ_04188 1.9e-275 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HGCOOKCJ_04189 5.9e-117 ydfE S Flavin reductase like domain
HGCOOKCJ_04190 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
HGCOOKCJ_04191 1.5e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HGCOOKCJ_04193 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
HGCOOKCJ_04194 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGCOOKCJ_04195 0.0 ydfJ S drug exporters of the RND superfamily
HGCOOKCJ_04196 1.9e-177 S Alpha/beta hydrolase family
HGCOOKCJ_04197 5.9e-118 S Protein of unknown function (DUF554)
HGCOOKCJ_04198 3.2e-147 K Bacterial transcription activator, effector binding domain
HGCOOKCJ_04199 1.6e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HGCOOKCJ_04200 9.6e-112 ydfN C nitroreductase
HGCOOKCJ_04201 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HGCOOKCJ_04202 8.8e-63 mhqP S DoxX
HGCOOKCJ_04203 1.3e-57 traF CO Thioredoxin
HGCOOKCJ_04204 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
HGCOOKCJ_04205 6.3e-29
HGCOOKCJ_04207 4.4e-118 ydfR S Protein of unknown function (DUF421)
HGCOOKCJ_04208 5.2e-122 ydfS S Protein of unknown function (DUF421)
HGCOOKCJ_04209 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
HGCOOKCJ_04210 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
HGCOOKCJ_04211 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
HGCOOKCJ_04212 1.5e-101 K Bacterial regulatory proteins, tetR family
HGCOOKCJ_04213 7.3e-53 S DoxX-like family
HGCOOKCJ_04214 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
HGCOOKCJ_04215 4.2e-308 expZ S ABC transporter
HGCOOKCJ_04216 4e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HGCOOKCJ_04217 4.6e-91 dinB S DinB family
HGCOOKCJ_04218 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
HGCOOKCJ_04219 0.0 ydgH S drug exporters of the RND superfamily
HGCOOKCJ_04220 1e-113 drgA C nitroreductase
HGCOOKCJ_04221 1.1e-69 ydgJ K Winged helix DNA-binding domain
HGCOOKCJ_04222 2.5e-209 tcaB EGP Major facilitator Superfamily
HGCOOKCJ_04223 1.2e-121 ydhB S membrane transporter protein
HGCOOKCJ_04224 6.5e-122 ydhC K FCD
HGCOOKCJ_04225 3.3e-244 ydhD M Glycosyl hydrolase
HGCOOKCJ_04226 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HGCOOKCJ_04227 1.9e-127
HGCOOKCJ_04228 1.4e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HGCOOKCJ_04229 4.6e-69 frataxin S Domain of unknown function (DU1801)
HGCOOKCJ_04231 4.1e-86 K Acetyltransferase (GNAT) domain
HGCOOKCJ_04232 1.8e-184 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HGCOOKCJ_04233 1.7e-99 ydhK M Protein of unknown function (DUF1541)
HGCOOKCJ_04234 4.6e-200 pbuE EGP Major facilitator Superfamily
HGCOOKCJ_04235 1.1e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HGCOOKCJ_04236 3.5e-52 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HGCOOKCJ_04237 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGCOOKCJ_04238 2.4e-288 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HGCOOKCJ_04239 3.9e-133 ydhQ K UTRA
HGCOOKCJ_04240 9.2e-172 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HGCOOKCJ_04241 4.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
HGCOOKCJ_04242 7.3e-216 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HGCOOKCJ_04243 8.7e-78 ydhU P Catalase
HGCOOKCJ_04244 1.1e-16 ydhU P Manganese containing catalase
HGCOOKCJ_04247 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
HGCOOKCJ_04248 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HGCOOKCJ_04249 1.2e-84 gerD
HGCOOKCJ_04250 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HGCOOKCJ_04251 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HGCOOKCJ_04252 9.7e-66 ybaK S Protein of unknown function (DUF2521)
HGCOOKCJ_04253 8.2e-145 ybaJ Q Methyltransferase domain
HGCOOKCJ_04254 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HGCOOKCJ_04255 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HGCOOKCJ_04256 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HGCOOKCJ_04257 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGCOOKCJ_04258 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGCOOKCJ_04259 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGCOOKCJ_04260 3.6e-58 rplQ J Ribosomal protein L17
HGCOOKCJ_04261 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGCOOKCJ_04262 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HGCOOKCJ_04263 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HGCOOKCJ_04264 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HGCOOKCJ_04265 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HGCOOKCJ_04266 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
HGCOOKCJ_04267 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HGCOOKCJ_04268 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HGCOOKCJ_04269 1.8e-72 rplO J binds to the 23S rRNA
HGCOOKCJ_04270 1.9e-23 rpmD J Ribosomal protein L30
HGCOOKCJ_04271 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HGCOOKCJ_04272 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HGCOOKCJ_04273 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HGCOOKCJ_04274 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HGCOOKCJ_04275 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HGCOOKCJ_04276 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HGCOOKCJ_04277 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HGCOOKCJ_04278 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HGCOOKCJ_04279 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HGCOOKCJ_04280 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HGCOOKCJ_04281 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HGCOOKCJ_04282 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HGCOOKCJ_04283 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HGCOOKCJ_04284 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HGCOOKCJ_04285 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HGCOOKCJ_04286 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HGCOOKCJ_04287 3e-105 rplD J Forms part of the polypeptide exit tunnel
HGCOOKCJ_04288 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HGCOOKCJ_04289 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HGCOOKCJ_04290 9.1e-186 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HGCOOKCJ_04291 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HGCOOKCJ_04292 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HGCOOKCJ_04293 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HGCOOKCJ_04294 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HGCOOKCJ_04295 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HGCOOKCJ_04296 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGCOOKCJ_04297 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGCOOKCJ_04298 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
HGCOOKCJ_04299 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HGCOOKCJ_04300 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HGCOOKCJ_04301 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HGCOOKCJ_04302 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HGCOOKCJ_04303 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
HGCOOKCJ_04304 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HGCOOKCJ_04305 4.4e-115 sigH K Belongs to the sigma-70 factor family
HGCOOKCJ_04306 1.2e-88 yacP S RNA-binding protein containing a PIN domain
HGCOOKCJ_04307 1.2e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HGCOOKCJ_04308 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HGCOOKCJ_04309 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HGCOOKCJ_04310 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
HGCOOKCJ_04311 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HGCOOKCJ_04312 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HGCOOKCJ_04313 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HGCOOKCJ_04314 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HGCOOKCJ_04315 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HGCOOKCJ_04316 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HGCOOKCJ_04317 0.0 clpC O Belongs to the ClpA ClpB family
HGCOOKCJ_04318 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HGCOOKCJ_04319 4.7e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HGCOOKCJ_04320 2.9e-76 ctsR K Belongs to the CtsR family
HGCOOKCJ_04321 3.4e-31 csfB S Inhibitor of sigma-G Gin
HGCOOKCJ_04322 4.7e-103 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HGCOOKCJ_04323 4.5e-203 yaaN P Belongs to the TelA family
HGCOOKCJ_04324 1.1e-275 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HGCOOKCJ_04325 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HGCOOKCJ_04326 2.2e-54 yaaQ S protein conserved in bacteria
HGCOOKCJ_04327 1.5e-71 yaaR S protein conserved in bacteria
HGCOOKCJ_04328 2.2e-182 holB 2.7.7.7 L DNA polymerase III
HGCOOKCJ_04329 2.1e-146 yaaT S stage 0 sporulation protein
HGCOOKCJ_04330 4.8e-31 yabA L Involved in initiation control of chromosome replication
HGCOOKCJ_04331 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
HGCOOKCJ_04332 1.5e-49 yazA L endonuclease containing a URI domain
HGCOOKCJ_04333 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HGCOOKCJ_04334 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HGCOOKCJ_04335 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HGCOOKCJ_04336 1.8e-144 tatD L hydrolase, TatD
HGCOOKCJ_04337 4.3e-194 rpfB GH23 T protein conserved in bacteria
HGCOOKCJ_04338 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HGCOOKCJ_04339 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HGCOOKCJ_04340 3.3e-137 yabG S peptidase
HGCOOKCJ_04341 7.8e-39 veg S protein conserved in bacteria
HGCOOKCJ_04342 8.3e-27 sspF S DNA topological change
HGCOOKCJ_04343 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HGCOOKCJ_04344 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HGCOOKCJ_04345 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HGCOOKCJ_04346 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HGCOOKCJ_04347 6.6e-230 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HGCOOKCJ_04348 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HGCOOKCJ_04349 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HGCOOKCJ_04350 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HGCOOKCJ_04351 2.4e-39 yabK S Peptide ABC transporter permease
HGCOOKCJ_04352 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HGCOOKCJ_04353 1.5e-92 spoVT K stage V sporulation protein
HGCOOKCJ_04354 2.4e-287 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HGCOOKCJ_04355 2.7e-245 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HGCOOKCJ_04356 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HGCOOKCJ_04357 1.5e-49 yabP S Sporulation protein YabP
HGCOOKCJ_04358 3.9e-108 yabQ S spore cortex biosynthesis protein
HGCOOKCJ_04359 1.1e-44 divIC D Septum formation initiator
HGCOOKCJ_04360 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HGCOOKCJ_04363 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HGCOOKCJ_04364 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
HGCOOKCJ_04365 6.7e-187 KLT serine threonine protein kinase
HGCOOKCJ_04366 3.5e-274 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HGCOOKCJ_04367 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HGCOOKCJ_04368 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HGCOOKCJ_04369 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HGCOOKCJ_04370 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HGCOOKCJ_04371 3.1e-153 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HGCOOKCJ_04372 8.9e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HGCOOKCJ_04373 4.7e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HGCOOKCJ_04374 1.5e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HGCOOKCJ_04375 1.6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HGCOOKCJ_04376 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HGCOOKCJ_04377 8.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HGCOOKCJ_04378 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HGCOOKCJ_04379 4.1e-30 yazB K transcriptional
HGCOOKCJ_04380 3.7e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HGCOOKCJ_04381 1.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HGCOOKCJ_04382 1.4e-281 cisA2 L Recombinase
HGCOOKCJ_04383 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
HGCOOKCJ_04384 6e-183 arsB 1.20.4.1 P Arsenic resistance protein
HGCOOKCJ_04385 2.8e-73 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGCOOKCJ_04386 1.6e-54 arsR K ArsR family transcriptional regulator
HGCOOKCJ_04387 1.1e-152 yqcI S YqcI/YcgG family
HGCOOKCJ_04388 1.6e-96 S Tetratricopeptide repeat
HGCOOKCJ_04391 3.8e-277 A Pre-toxin TG
HGCOOKCJ_04392 1.1e-104 S Suppressor of fused protein (SUFU)
HGCOOKCJ_04394 5e-60
HGCOOKCJ_04396 1.1e-144 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HGCOOKCJ_04397 2.6e-68 S Bacteriophage holin family
HGCOOKCJ_04398 4.8e-165 xepA
HGCOOKCJ_04399 1.3e-23
HGCOOKCJ_04400 4.1e-56 xkdW S XkdW protein
HGCOOKCJ_04401 2e-221
HGCOOKCJ_04402 9.6e-40
HGCOOKCJ_04403 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HGCOOKCJ_04404 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HGCOOKCJ_04405 9.6e-71 xkdS S Protein of unknown function (DUF2634)
HGCOOKCJ_04406 1.8e-38 xkdR S Protein of unknown function (DUF2577)
HGCOOKCJ_04407 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
HGCOOKCJ_04408 9e-114 xkdP S Lysin motif
HGCOOKCJ_04409 0.0 xkdO L Transglycosylase SLT domain
HGCOOKCJ_04410 1.8e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
HGCOOKCJ_04412 3.6e-76 xkdM S Phage tail tube protein
HGCOOKCJ_04413 5.5e-256 xkdK S Phage tail sheath C-terminal domain
HGCOOKCJ_04414 3.2e-26
HGCOOKCJ_04415 1.4e-77
HGCOOKCJ_04416 4.3e-94 S Bacteriophage HK97-gp10, putative tail-component
HGCOOKCJ_04417 6.7e-65 yqbH S Domain of unknown function (DUF3599)
HGCOOKCJ_04418 2.1e-67 S Protein of unknown function (DUF3199)
HGCOOKCJ_04419 3.6e-51 S YqbF, hypothetical protein domain
HGCOOKCJ_04420 1.9e-167 xkdG S Phage capsid family
HGCOOKCJ_04421 5.1e-128 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HGCOOKCJ_04422 2e-115
HGCOOKCJ_04423 5.7e-169 S Phage Mu protein F like protein
HGCOOKCJ_04424 5.9e-296 yqbA S portal protein
HGCOOKCJ_04425 2.4e-253 S phage terminase, large subunit
HGCOOKCJ_04426 6.3e-107 yqaS L DNA packaging
HGCOOKCJ_04428 6.5e-81 L Transposase
HGCOOKCJ_04429 1.6e-166
HGCOOKCJ_04430 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
HGCOOKCJ_04431 7.2e-74 rusA L Endodeoxyribonuclease RusA
HGCOOKCJ_04433 5.9e-168 xkdC L IstB-like ATP binding protein
HGCOOKCJ_04434 1e-122 3.1.3.16 L DnaD domain protein
HGCOOKCJ_04435 2.5e-155 recT L RecT family
HGCOOKCJ_04436 1.5e-180 yqaJ L YqaJ-like viral recombinase domain
HGCOOKCJ_04440 1.2e-103
HGCOOKCJ_04442 6.5e-37 K Helix-turn-helix XRE-family like proteins
HGCOOKCJ_04443 1.1e-56 K sequence-specific DNA binding
HGCOOKCJ_04445 1e-101 adk 2.7.4.3 F adenylate kinase activity
HGCOOKCJ_04446 1.4e-100 yqaB E IrrE N-terminal-like domain
HGCOOKCJ_04447 2.7e-182 yaaC S YaaC-like Protein
HGCOOKCJ_04448 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HGCOOKCJ_04449 5.2e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HGCOOKCJ_04450 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HGCOOKCJ_04451 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HGCOOKCJ_04452 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HGCOOKCJ_04453 1.3e-09
HGCOOKCJ_04454 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HGCOOKCJ_04455 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HGCOOKCJ_04456 5.6e-215 yaaH M Glycoside Hydrolase Family
HGCOOKCJ_04457 2.4e-98 yaaI Q COG1335 Amidases related to nicotinamidase
HGCOOKCJ_04458 1e-84 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HGCOOKCJ_04459 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HGCOOKCJ_04460 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HGCOOKCJ_04461 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HGCOOKCJ_04462 7.9e-32 yaaL S Protein of unknown function (DUF2508)
HGCOOKCJ_04463 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
HGCOOKCJ_04464 6.7e-270 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGCOOKCJ_04465 2.4e-137 S COG0457 FOG TPR repeat
HGCOOKCJ_04468 4.4e-64 K Transcriptional regulator
HGCOOKCJ_04470 3.3e-25 traI 2.5.1.15 U relaxase mobilization nuclease domain protein
HGCOOKCJ_04471 5.5e-21 S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HGCOOKCJ_04473 6.3e-177 L Replication protein
HGCOOKCJ_04474 3.4e-39 S COG NOG14552 non supervised orthologous group
HGCOOKCJ_04479 2e-08
HGCOOKCJ_04481 2e-08
HGCOOKCJ_04486 2.5e-12

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)