ORF_ID e_value Gene_name EC_number CAZy COGs Description
FHJKHKDH_00005 2e-08
FHJKHKDH_00012 1.3e-09
FHJKHKDH_00013 7.8e-08
FHJKHKDH_00022 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FHJKHKDH_00023 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FHJKHKDH_00024 1.4e-176 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
FHJKHKDH_00025 7.6e-285 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
FHJKHKDH_00026 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
FHJKHKDH_00027 1.9e-75 tspO T membrane
FHJKHKDH_00028 4.4e-205 cotI S Spore coat protein
FHJKHKDH_00029 6.9e-217 cotSA M Glycosyl transferases group 1
FHJKHKDH_00030 9.7e-205 cotS S Seems to be required for the assembly of the CotSA protein in spores
FHJKHKDH_00032 1.7e-232 ytcC M Glycosyltransferase Family 4
FHJKHKDH_00033 3.1e-178 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
FHJKHKDH_00034 5.4e-242 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FHJKHKDH_00035 8.7e-153 galU 2.7.7.9 M Nucleotidyl transferase
FHJKHKDH_00036 1.3e-131 dksA T COG1734 DnaK suppressor protein
FHJKHKDH_00037 1.9e-272 menF 5.4.4.2 HQ Isochorismate synthase
FHJKHKDH_00038 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FHJKHKDH_00039 7.4e-152 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
FHJKHKDH_00040 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FHJKHKDH_00041 2e-272 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
FHJKHKDH_00042 1.2e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
FHJKHKDH_00043 2e-169 troA P Belongs to the bacterial solute-binding protein 9 family
FHJKHKDH_00044 3.6e-137 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
FHJKHKDH_00045 6.3e-230 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
FHJKHKDH_00046 7.5e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
FHJKHKDH_00047 1.1e-24 S Domain of Unknown Function (DUF1540)
FHJKHKDH_00048 3.6e-188 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
FHJKHKDH_00049 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
FHJKHKDH_00050 6.1e-41 rpmE2 J Ribosomal protein L31
FHJKHKDH_00051 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
FHJKHKDH_00052 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
FHJKHKDH_00053 4e-72 ytkA S YtkA-like
FHJKHKDH_00055 2.1e-76 dps P Belongs to the Dps family
FHJKHKDH_00056 7.8e-62 ytkC S Bacteriophage holin family
FHJKHKDH_00057 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
FHJKHKDH_00058 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
FHJKHKDH_00059 4.1e-144 ytlC P ABC transporter
FHJKHKDH_00060 1.8e-187 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
FHJKHKDH_00061 2.7e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
FHJKHKDH_00062 1.6e-38 ytmB S Protein of unknown function (DUF2584)
FHJKHKDH_00063 2.6e-310 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FHJKHKDH_00064 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FHJKHKDH_00065 0.0 asnB 6.3.5.4 E Asparagine synthase
FHJKHKDH_00066 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
FHJKHKDH_00067 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FHJKHKDH_00068 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
FHJKHKDH_00069 7.5e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
FHJKHKDH_00070 2.2e-105 ytqB J Putative rRNA methylase
FHJKHKDH_00071 8.1e-190 yhcC S Fe-S oxidoreductase
FHJKHKDH_00072 6.7e-41 ytzC S Protein of unknown function (DUF2524)
FHJKHKDH_00074 5.1e-66 ytrA K GntR family transcriptional regulator
FHJKHKDH_00075 4.6e-160 ytrB P abc transporter atp-binding protein
FHJKHKDH_00076 1.2e-145 P ABC-2 family transporter protein
FHJKHKDH_00077 9.8e-127
FHJKHKDH_00078 3.1e-127 ytrE V ABC transporter, ATP-binding protein
FHJKHKDH_00079 5.5e-234 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
FHJKHKDH_00080 2.6e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FHJKHKDH_00081 1.2e-185 T PhoQ Sensor
FHJKHKDH_00082 1.1e-138 bceA V ABC transporter, ATP-binding protein
FHJKHKDH_00083 0.0 bceB V ABC transporter (permease)
FHJKHKDH_00084 3.9e-43 yttA 2.7.13.3 S Pfam Transposase IS66
FHJKHKDH_00085 1.7e-210 yttB EGP Major facilitator Superfamily
FHJKHKDH_00086 3.9e-142 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
FHJKHKDH_00087 7.7e-55 ytvB S Protein of unknown function (DUF4257)
FHJKHKDH_00088 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
FHJKHKDH_00089 8.1e-51 ytwF P Sulfurtransferase
FHJKHKDH_00090 2.6e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
FHJKHKDH_00091 4.4e-144 amyC P ABC transporter (permease)
FHJKHKDH_00092 9e-167 amyD P ABC transporter
FHJKHKDH_00093 1.5e-244 msmE G Bacterial extracellular solute-binding protein
FHJKHKDH_00094 4.3e-189 msmR K Transcriptional regulator
FHJKHKDH_00095 5.4e-172 ytaP S Acetyl xylan esterase (AXE1)
FHJKHKDH_00096 5.2e-141 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
FHJKHKDH_00097 1.1e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
FHJKHKDH_00098 1.1e-217 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
FHJKHKDH_00099 3.8e-125 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FHJKHKDH_00100 8.4e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FHJKHKDH_00101 1.8e-223 bioI 1.14.14.46 C Cytochrome P450
FHJKHKDH_00102 9e-136 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
FHJKHKDH_00103 1.3e-149 ytcP G COG0395 ABC-type sugar transport system, permease component
FHJKHKDH_00104 1.5e-288 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
FHJKHKDH_00105 0.0 ytdP K Transcriptional regulator
FHJKHKDH_00106 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
FHJKHKDH_00107 1e-217 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
FHJKHKDH_00108 5.1e-72 yteS G transport
FHJKHKDH_00109 3.2e-247 yteT S Oxidoreductase family, C-terminal alpha/beta domain
FHJKHKDH_00110 4.5e-115 yteU S Integral membrane protein
FHJKHKDH_00111 3.1e-26 yteV S Sporulation protein Cse60
FHJKHKDH_00112 3.7e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
FHJKHKDH_00113 8.2e-232 ytfP S HI0933-like protein
FHJKHKDH_00114 2.5e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
FHJKHKDH_00115 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
FHJKHKDH_00116 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
FHJKHKDH_00117 4.8e-131 ythP V ABC transporter
FHJKHKDH_00118 1.1e-201 ythQ U Bacterial ABC transporter protein EcsB
FHJKHKDH_00119 3e-224 pbuO S permease
FHJKHKDH_00120 1.7e-270 pepV 3.5.1.18 E Dipeptidase
FHJKHKDH_00121 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
FHJKHKDH_00122 1.2e-100 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FHJKHKDH_00123 8.5e-165 ytlQ
FHJKHKDH_00124 1.1e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
FHJKHKDH_00125 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
FHJKHKDH_00126 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
FHJKHKDH_00127 2e-45 ytzH S YtzH-like protein
FHJKHKDH_00128 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
FHJKHKDH_00129 9.3e-150 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
FHJKHKDH_00130 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
FHJKHKDH_00131 2.2e-51 ytzB S small secreted protein
FHJKHKDH_00132 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
FHJKHKDH_00133 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
FHJKHKDH_00134 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
FHJKHKDH_00135 9.8e-149 ytpQ S Belongs to the UPF0354 family
FHJKHKDH_00136 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
FHJKHKDH_00137 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
FHJKHKDH_00138 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
FHJKHKDH_00139 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
FHJKHKDH_00140 6.6e-17 ytxH S COG4980 Gas vesicle protein
FHJKHKDH_00141 6.3e-54 ytxJ O Protein of unknown function (DUF2847)
FHJKHKDH_00142 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
FHJKHKDH_00143 8.4e-182 ccpA K catabolite control protein A
FHJKHKDH_00144 2.1e-146 motA N flagellar motor
FHJKHKDH_00145 1.4e-125 motS N Flagellar motor protein
FHJKHKDH_00146 5.4e-225 acuC BQ histone deacetylase
FHJKHKDH_00147 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
FHJKHKDH_00148 1.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
FHJKHKDH_00149 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
FHJKHKDH_00150 8e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FHJKHKDH_00152 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FHJKHKDH_00153 5.3e-309 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
FHJKHKDH_00154 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
FHJKHKDH_00155 1e-108 yttP K Transcriptional regulator
FHJKHKDH_00156 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
FHJKHKDH_00157 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FHJKHKDH_00158 1.4e-237 brnQ E Component of the transport system for branched-chain amino acids
FHJKHKDH_00159 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
FHJKHKDH_00160 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FHJKHKDH_00161 2e-29 sspB S spore protein
FHJKHKDH_00162 1.7e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
FHJKHKDH_00163 0.0 ytcJ S amidohydrolase
FHJKHKDH_00164 1.4e-147 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FHJKHKDH_00165 1.8e-179 sppA OU signal peptide peptidase SppA
FHJKHKDH_00166 2.5e-86 yteJ S RDD family
FHJKHKDH_00167 5.6e-116 ytfI S Protein of unknown function (DUF2953)
FHJKHKDH_00168 8.7e-70 ytfJ S Sporulation protein YtfJ
FHJKHKDH_00169 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FHJKHKDH_00170 7.8e-164 ytxK 2.1.1.72 L DNA methylase
FHJKHKDH_00171 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FHJKHKDH_00172 1.4e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
FHJKHKDH_00173 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
FHJKHKDH_00174 1.2e-266 argH 4.3.2.1 E argininosuccinate lyase
FHJKHKDH_00176 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FHJKHKDH_00177 1.7e-130 ytkL S Belongs to the UPF0173 family
FHJKHKDH_00178 2.9e-173 ytlI K LysR substrate binding domain
FHJKHKDH_00179 3.1e-98 ytmI K Acetyltransferase (GNAT) domain
FHJKHKDH_00180 3.1e-150 tcyK ET Bacterial periplasmic substrate-binding proteins
FHJKHKDH_00181 3.7e-148 tcyK M Bacterial periplasmic substrate-binding proteins
FHJKHKDH_00182 8.2e-123 tcyL P Binding-protein-dependent transport system inner membrane component
FHJKHKDH_00183 1.6e-118 tcyM U Binding-protein-dependent transport system inner membrane component
FHJKHKDH_00184 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
FHJKHKDH_00185 7.6e-183 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FHJKHKDH_00186 2.4e-46 ytnI O COG0695 Glutaredoxin and related proteins
FHJKHKDH_00187 3.2e-253 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FHJKHKDH_00188 3.4e-126 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
FHJKHKDH_00189 1.6e-238 ytnL 3.5.1.47 E hydrolase activity
FHJKHKDH_00190 1.4e-156 ytnM S membrane transporter protein
FHJKHKDH_00191 8e-241 ytoI K transcriptional regulator containing CBS domains
FHJKHKDH_00192 2.4e-47 ytpI S YtpI-like protein
FHJKHKDH_00193 5.1e-181 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
FHJKHKDH_00194 9.2e-29
FHJKHKDH_00195 2.4e-68 ytrI
FHJKHKDH_00196 3.2e-56 ytrH S Sporulation protein YtrH
FHJKHKDH_00197 0.0 dnaE 2.7.7.7 L DNA polymerase
FHJKHKDH_00198 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
FHJKHKDH_00199 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FHJKHKDH_00200 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
FHJKHKDH_00201 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
FHJKHKDH_00202 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
FHJKHKDH_00203 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
FHJKHKDH_00204 2.2e-191 ytvI S sporulation integral membrane protein YtvI
FHJKHKDH_00205 4.7e-71 yeaL S membrane
FHJKHKDH_00206 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
FHJKHKDH_00207 4.1e-242 icd 1.1.1.42 C isocitrate
FHJKHKDH_00208 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
FHJKHKDH_00209 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FHJKHKDH_00210 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
FHJKHKDH_00211 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FHJKHKDH_00212 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
FHJKHKDH_00213 2.8e-106 ytaF P Probably functions as a manganese efflux pump
FHJKHKDH_00214 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FHJKHKDH_00215 8.9e-161 ytbE S reductase
FHJKHKDH_00216 7.3e-201 ytbD EGP Major facilitator Superfamily
FHJKHKDH_00217 9.9e-67 ytcD K Transcriptional regulator
FHJKHKDH_00218 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
FHJKHKDH_00219 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FHJKHKDH_00220 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FHJKHKDH_00221 7.7e-266 dnaB L Membrane attachment protein
FHJKHKDH_00222 6.6e-173 dnaI L Primosomal protein DnaI
FHJKHKDH_00223 4.9e-111 ytxB S SNARE associated Golgi protein
FHJKHKDH_00224 3.8e-159 ytxC S YtxC-like family
FHJKHKDH_00225 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FHJKHKDH_00226 7.3e-149 ysaA S HAD-hyrolase-like
FHJKHKDH_00227 0.0 lytS 2.7.13.3 T Histidine kinase
FHJKHKDH_00228 1.6e-129 lytT T COG3279 Response regulator of the LytR AlgR family
FHJKHKDH_00229 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
FHJKHKDH_00230 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
FHJKHKDH_00232 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FHJKHKDH_00233 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
FHJKHKDH_00234 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FHJKHKDH_00235 7.5e-45 ysdA S Membrane
FHJKHKDH_00236 3.5e-67 ysdB S Sigma-w pathway protein YsdB
FHJKHKDH_00237 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
FHJKHKDH_00238 1.2e-188 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
FHJKHKDH_00239 3.9e-292 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
FHJKHKDH_00240 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
FHJKHKDH_00241 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
FHJKHKDH_00242 3.5e-146 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
FHJKHKDH_00243 2.8e-221 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
FHJKHKDH_00244 1.4e-253 araN G carbohydrate transport
FHJKHKDH_00245 1.4e-167 araP G carbohydrate transport
FHJKHKDH_00246 3.4e-144 araQ G transport system permease
FHJKHKDH_00247 1e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
FHJKHKDH_00248 0.0 cstA T Carbon starvation protein
FHJKHKDH_00249 4.5e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
FHJKHKDH_00250 2.1e-257 glcF C Glycolate oxidase
FHJKHKDH_00251 1.8e-262 glcD 1.1.3.15 C Glycolate oxidase subunit
FHJKHKDH_00252 1.3e-207 ysfB KT regulator
FHJKHKDH_00253 5.8e-32 sspI S Belongs to the SspI family
FHJKHKDH_00254 1e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FHJKHKDH_00255 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FHJKHKDH_00256 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
FHJKHKDH_00257 5.4e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FHJKHKDH_00258 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FHJKHKDH_00259 1.3e-85 cvpA S membrane protein, required for colicin V production
FHJKHKDH_00260 0.0 polX L COG1796 DNA polymerase IV (family X)
FHJKHKDH_00261 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
FHJKHKDH_00262 2.8e-67 yshE S membrane
FHJKHKDH_00263 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
FHJKHKDH_00264 2.7e-100 fadR K Transcriptional regulator
FHJKHKDH_00265 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
FHJKHKDH_00266 4.5e-135 etfB C Electron transfer flavoprotein
FHJKHKDH_00267 2.1e-177 etfA C Electron transfer flavoprotein
FHJKHKDH_00269 1.4e-302 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
FHJKHKDH_00270 2e-52 trxA O Belongs to the thioredoxin family
FHJKHKDH_00271 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
FHJKHKDH_00272 6.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
FHJKHKDH_00273 1.2e-79 yslB S Protein of unknown function (DUF2507)
FHJKHKDH_00274 2.4e-107 sdhC C succinate dehydrogenase
FHJKHKDH_00275 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
FHJKHKDH_00276 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
FHJKHKDH_00277 1.6e-76 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
FHJKHKDH_00278 3.3e-30 gerE K Transcriptional regulator
FHJKHKDH_00279 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
FHJKHKDH_00280 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
FHJKHKDH_00281 2.9e-196 gerM S COG5401 Spore germination protein
FHJKHKDH_00282 9e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FHJKHKDH_00283 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FHJKHKDH_00284 7e-92 ysnB S Phosphoesterase
FHJKHKDH_00286 2e-26 ysnF S protein conserved in bacteria
FHJKHKDH_00287 3.3e-77 ysnE K acetyltransferase
FHJKHKDH_00289 0.0 ilvB 2.2.1.6 E Acetolactate synthase
FHJKHKDH_00290 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
FHJKHKDH_00291 9.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FHJKHKDH_00292 2.9e-290 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FHJKHKDH_00293 3.7e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
FHJKHKDH_00294 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FHJKHKDH_00295 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FHJKHKDH_00296 2.3e-187 ysoA H Tetratricopeptide repeat
FHJKHKDH_00297 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
FHJKHKDH_00298 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FHJKHKDH_00299 2.8e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
FHJKHKDH_00300 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FHJKHKDH_00301 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
FHJKHKDH_00302 5.4e-89 ysxD
FHJKHKDH_00303 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FHJKHKDH_00304 3.6e-146 hemX O cytochrome C
FHJKHKDH_00305 3.3e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
FHJKHKDH_00306 7.1e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
FHJKHKDH_00307 1.8e-181 hemB 4.2.1.24 H Belongs to the ALAD family
FHJKHKDH_00308 2.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
FHJKHKDH_00309 1.6e-217 spoVID M stage VI sporulation protein D
FHJKHKDH_00310 2.3e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FHJKHKDH_00311 1.6e-25
FHJKHKDH_00312 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
FHJKHKDH_00313 1.4e-245 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
FHJKHKDH_00314 3.3e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
FHJKHKDH_00315 1.9e-162 spoIIB S Sporulation related domain
FHJKHKDH_00316 2.8e-102 maf D septum formation protein Maf
FHJKHKDH_00317 1.4e-66 radC E Belongs to the UPF0758 family
FHJKHKDH_00318 2.7e-226 S Recombinase
FHJKHKDH_00319 1.8e-72 S Pfam:Peptidase_M78
FHJKHKDH_00320 1.7e-62 S sequence-specific DNA binding
FHJKHKDH_00321 8.8e-09 plcR K helix-turn-helix
FHJKHKDH_00324 6.6e-20 S Uncharacterized protein YqaH
FHJKHKDH_00326 7.6e-92 S DNA protection
FHJKHKDH_00327 4.6e-166 tadZ D AAA domain
FHJKHKDH_00328 4.3e-74 S Protein of unknown function (DUF669)
FHJKHKDH_00329 0.0 S hydrolase activity
FHJKHKDH_00330 2e-71
FHJKHKDH_00331 1.1e-92 S nuclease activity
FHJKHKDH_00333 6e-46 S DNA N-6-adenine-methyltransferase
FHJKHKDH_00337 3.3e-72 S YopX protein
FHJKHKDH_00339 4.7e-61
FHJKHKDH_00340 2.9e-64 S regulation of transcription, DNA-dependent
FHJKHKDH_00341 9.7e-20 N PFAM YcfA family protein
FHJKHKDH_00345 1.1e-27 L HNH endonuclease
FHJKHKDH_00346 1.3e-16
FHJKHKDH_00347 3.5e-175 S Phage Terminase
FHJKHKDH_00348 4.3e-113 S Phage portal protein
FHJKHKDH_00349 4.2e-48 S Caudovirus prohead serine protease
FHJKHKDH_00350 2.1e-89 S Phage capsid family
FHJKHKDH_00351 1e-10 S Phage gp6-like head-tail connector protein
FHJKHKDH_00352 1.2e-07 S head-tail adaptor
FHJKHKDH_00353 1.6e-14 S Bacteriophage HK97-gp10, putative tail-component
FHJKHKDH_00354 1.9e-17
FHJKHKDH_00355 2.5e-54 S phage major tail protein, phi13 family
FHJKHKDH_00357 9.5e-150 D Phage-related minor tail protein
FHJKHKDH_00358 3.3e-43 S Phage tail protein
FHJKHKDH_00359 2.5e-102 mur1 NU Prophage endopeptidase tail
FHJKHKDH_00360 3.3e-62
FHJKHKDH_00361 1.8e-86
FHJKHKDH_00363 1.5e-10 S Phage uncharacterised protein (Phage_XkdX)
FHJKHKDH_00364 7.1e-58 S Bacteriophage holin family
FHJKHKDH_00365 8.2e-126 xlyB 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
FHJKHKDH_00366 1.1e-30 S Domain of unknown function (DUF4917)
FHJKHKDH_00368 9.3e-08
FHJKHKDH_00369 5.4e-51 radC E Belongs to the UPF0758 family
FHJKHKDH_00370 1.8e-184 mreB D Rod shape-determining protein MreB
FHJKHKDH_00371 1.1e-156 mreC M Involved in formation and maintenance of cell shape
FHJKHKDH_00372 1.4e-84 mreD M shape-determining protein
FHJKHKDH_00373 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
FHJKHKDH_00374 2.5e-144 minD D Belongs to the ParA family
FHJKHKDH_00375 1.9e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
FHJKHKDH_00376 5.9e-160 spoIVFB S Stage IV sporulation protein
FHJKHKDH_00377 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
FHJKHKDH_00378 4.1e-56 ysxB J ribosomal protein
FHJKHKDH_00379 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
FHJKHKDH_00380 1.9e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
FHJKHKDH_00381 9.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FHJKHKDH_00382 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
FHJKHKDH_00383 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
FHJKHKDH_00384 2.3e-93 niaR S small molecule binding protein (contains 3H domain)
FHJKHKDH_00385 3.1e-228 nifS 2.8.1.7 E Cysteine desulfurase
FHJKHKDH_00386 4.4e-302 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
FHJKHKDH_00387 4.7e-157 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
FHJKHKDH_00388 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FHJKHKDH_00389 8.3e-157 safA M spore coat assembly protein SafA
FHJKHKDH_00390 8.5e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
FHJKHKDH_00391 1.9e-127 yebC K transcriptional regulatory protein
FHJKHKDH_00392 2.9e-260 alsT E Sodium alanine symporter
FHJKHKDH_00393 3.1e-51 S Family of unknown function (DUF5412)
FHJKHKDH_00395 6.5e-119 yrzF T serine threonine protein kinase
FHJKHKDH_00396 4.1e-192 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
FHJKHKDH_00397 5.3e-253 csbX EGP Major facilitator Superfamily
FHJKHKDH_00398 4.8e-93 bofC S BofC C-terminal domain
FHJKHKDH_00399 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
FHJKHKDH_00400 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
FHJKHKDH_00401 2.6e-18 yrzS S Protein of unknown function (DUF2905)
FHJKHKDH_00402 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FHJKHKDH_00403 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
FHJKHKDH_00404 1.1e-38 yajC U Preprotein translocase subunit YajC
FHJKHKDH_00405 3.8e-73 yrzE S Protein of unknown function (DUF3792)
FHJKHKDH_00406 1.7e-111 yrbG S membrane
FHJKHKDH_00407 2.2e-269 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
FHJKHKDH_00408 1.6e-48 yrzD S Post-transcriptional regulator
FHJKHKDH_00409 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FHJKHKDH_00410 4.3e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
FHJKHKDH_00411 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
FHJKHKDH_00412 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
FHJKHKDH_00413 8.6e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FHJKHKDH_00414 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FHJKHKDH_00415 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
FHJKHKDH_00416 1.1e-262 lytH 3.5.1.28 M COG3103 SH3 domain protein
FHJKHKDH_00418 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
FHJKHKDH_00419 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FHJKHKDH_00420 9e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
FHJKHKDH_00421 3.3e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
FHJKHKDH_00422 1.2e-70 cymR K Transcriptional regulator
FHJKHKDH_00423 1.4e-212 iscS 2.8.1.7 E Cysteine desulfurase
FHJKHKDH_00424 6.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
FHJKHKDH_00425 1.4e-15 S COG0457 FOG TPR repeat
FHJKHKDH_00426 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
FHJKHKDH_00427 1.7e-81 yrrD S protein conserved in bacteria
FHJKHKDH_00428 9.8e-31 yrzR
FHJKHKDH_00429 8e-08 S Protein of unknown function (DUF3918)
FHJKHKDH_00430 7.6e-107 glnP P ABC transporter
FHJKHKDH_00431 1.8e-108 gluC P ABC transporter
FHJKHKDH_00432 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
FHJKHKDH_00433 2.9e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
FHJKHKDH_00434 7.8e-170 yrrI S AI-2E family transporter
FHJKHKDH_00435 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FHJKHKDH_00436 1.7e-41 yrzL S Belongs to the UPF0297 family
FHJKHKDH_00437 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FHJKHKDH_00438 1.2e-45 yrzB S Belongs to the UPF0473 family
FHJKHKDH_00439 5.3e-182 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FHJKHKDH_00440 2.9e-119 yrrM 2.1.1.104 S O-methyltransferase
FHJKHKDH_00441 2.9e-173 yegQ O Peptidase U32
FHJKHKDH_00442 2.7e-246 yegQ O COG0826 Collagenase and related proteases
FHJKHKDH_00443 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
FHJKHKDH_00444 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
FHJKHKDH_00445 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
FHJKHKDH_00446 4.2e-63 yrrS S Protein of unknown function (DUF1510)
FHJKHKDH_00447 3.5e-26 yrzA S Protein of unknown function (DUF2536)
FHJKHKDH_00448 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
FHJKHKDH_00449 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FHJKHKDH_00450 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
FHJKHKDH_00451 7.5e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
FHJKHKDH_00452 4.6e-35 yrhC S YrhC-like protein
FHJKHKDH_00453 1.4e-78 yrhD S Protein of unknown function (DUF1641)
FHJKHKDH_00454 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
FHJKHKDH_00455 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
FHJKHKDH_00457 1.8e-142 focA P Formate nitrite
FHJKHKDH_00460 1.1e-95 yrhH Q methyltransferase
FHJKHKDH_00461 1.8e-104 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
FHJKHKDH_00462 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
FHJKHKDH_00463 7.3e-46 yrhK S YrhK-like protein
FHJKHKDH_00464 6e-58 yrhL I Acyltransferase family
FHJKHKDH_00465 2.4e-246 yrhL I Acyltransferase family
FHJKHKDH_00466 3.8e-151 rsiV S Protein of unknown function (DUF3298)
FHJKHKDH_00467 1.6e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
FHJKHKDH_00468 1.6e-149 yrhO K Archaeal transcriptional regulator TrmB
FHJKHKDH_00469 3.6e-106 yrhP E LysE type translocator
FHJKHKDH_00470 1e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
FHJKHKDH_00471 0.0 levR K PTS system fructose IIA component
FHJKHKDH_00472 1.9e-74 levD 2.7.1.202 G PTS system fructose IIA component
FHJKHKDH_00473 6.9e-81 levE 2.7.1.202 G PTS system mannose fructose sorbose family
FHJKHKDH_00474 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
FHJKHKDH_00475 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
FHJKHKDH_00476 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
FHJKHKDH_00477 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
FHJKHKDH_00478 2.5e-197 adhA 1.1.1.1 C alcohol dehydrogenase
FHJKHKDH_00479 2.8e-46 yraB K helix_turn_helix, mercury resistance
FHJKHKDH_00480 1.1e-49 yraD M Spore coat protein
FHJKHKDH_00481 7.5e-26 yraE
FHJKHKDH_00482 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
FHJKHKDH_00483 3.2e-62 yraF M Spore coat protein
FHJKHKDH_00484 1.5e-36 yraG
FHJKHKDH_00485 3.8e-66 E Glyoxalase-like domain
FHJKHKDH_00486 1.6e-60 T sh3 domain protein
FHJKHKDH_00487 1.7e-60 T sh3 domain protein
FHJKHKDH_00488 6.2e-151 S Alpha beta hydrolase
FHJKHKDH_00489 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FHJKHKDH_00490 2.9e-156 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
FHJKHKDH_00491 5.9e-205 yraM S PrpF protein
FHJKHKDH_00492 3.4e-163 yraN K Transcriptional regulator
FHJKHKDH_00493 1e-224 yraO C Citrate transporter
FHJKHKDH_00494 4.5e-188 yrpG C Aldo/keto reductase family
FHJKHKDH_00495 2.1e-91 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
FHJKHKDH_00496 9.6e-114 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
FHJKHKDH_00497 1.1e-25 epsA I Passenger-associated-transport-repeat
FHJKHKDH_00498 9.9e-48 yjbR S YjbR
FHJKHKDH_00499 7.2e-118 bmrR K helix_turn_helix, mercury resistance
FHJKHKDH_00500 5.6e-98 flr S Flavin reductase like domain
FHJKHKDH_00501 6.4e-135 tktA 2.2.1.1 G COG3959 Transketolase, N-terminal subunit
FHJKHKDH_00502 3.5e-153 2.2.1.1 G Transketolase, pyrimidine binding domain
FHJKHKDH_00503 5.6e-114 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FHJKHKDH_00504 7.4e-210 rbtT P Major Facilitator Superfamily
FHJKHKDH_00506 4.3e-100 K helix_turn_helix gluconate operon transcriptional repressor
FHJKHKDH_00507 6.2e-123 yrpD S Domain of unknown function, YrpD
FHJKHKDH_00508 4.5e-146 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
FHJKHKDH_00509 4.9e-193 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
FHJKHKDH_00510 3.9e-164 aadK G Streptomycin adenylyltransferase
FHJKHKDH_00511 2.4e-89 yrdA S DinB family
FHJKHKDH_00512 4.4e-54 S Protein of unknown function (DUF2568)
FHJKHKDH_00513 4.5e-100 yrdC 3.5.1.19 Q Isochorismatase family
FHJKHKDH_00514 1.4e-226 cypA C Cytochrome P450
FHJKHKDH_00515 4.6e-15 yrdF K ribonuclease inhibitor
FHJKHKDH_00516 1.1e-78 bkdR K helix_turn_helix ASNC type
FHJKHKDH_00517 2.8e-137 azlC E AzlC protein
FHJKHKDH_00518 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
FHJKHKDH_00519 1.1e-226 brnQ E Component of the transport system for branched-chain amino acids
FHJKHKDH_00520 1.1e-32 C COG2041 Sulfite oxidase and related enzymes
FHJKHKDH_00521 4.1e-156 gltR K LysR substrate binding domain
FHJKHKDH_00522 6.5e-66 yodA S tautomerase
FHJKHKDH_00523 6.5e-152 czcD P COG1230 Co Zn Cd efflux system component
FHJKHKDH_00524 6e-199 trkA P Oxidoreductase
FHJKHKDH_00525 4.3e-158 yrdQ K Transcriptional regulator
FHJKHKDH_00526 2.3e-168 yrdR EG EamA-like transporter family
FHJKHKDH_00527 3.9e-16 S YrzO-like protein
FHJKHKDH_00528 7.9e-233 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
FHJKHKDH_00529 5.9e-82 bltD 2.3.1.57 K FR47-like protein
FHJKHKDH_00530 2.3e-210 blt EGP Major facilitator Superfamily
FHJKHKDH_00531 3.1e-150 bltR K helix_turn_helix, mercury resistance
FHJKHKDH_00532 6.4e-107 yrkC G Cupin domain
FHJKHKDH_00533 7.8e-39 yrkD S protein conserved in bacteria
FHJKHKDH_00534 2e-65 yrkE O DsrE/DsrF/DrsH-like family
FHJKHKDH_00535 4.6e-97 yrkF OP Belongs to the sulfur carrier protein TusA family
FHJKHKDH_00536 1.4e-206 yrkH P Rhodanese Homology Domain
FHJKHKDH_00537 5.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
FHJKHKDH_00538 1.7e-100 yrkJ S membrane transporter protein
FHJKHKDH_00539 2.8e-79 S Protein of unknown function with HXXEE motif
FHJKHKDH_00540 1.5e-97 ywrO S Flavodoxin-like fold
FHJKHKDH_00541 1.1e-103 yrkN K Acetyltransferase (GNAT) family
FHJKHKDH_00542 4.1e-223 yrkO P Protein of unknown function (DUF418)
FHJKHKDH_00543 1.1e-127 T Transcriptional regulator
FHJKHKDH_00544 9e-237 yrkQ T Histidine kinase
FHJKHKDH_00545 6.1e-62 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FHJKHKDH_00546 5.8e-94 yqaB E IrrE N-terminal-like domain
FHJKHKDH_00548 7.6e-97 adk 2.7.4.3 F adenylate kinase activity
FHJKHKDH_00550 1.1e-32 K sequence-specific DNA binding
FHJKHKDH_00551 5.9e-17 K Helix-turn-helix XRE-family like proteins
FHJKHKDH_00553 4.9e-102
FHJKHKDH_00557 9.5e-175 yqaJ L YqaJ-like viral recombinase domain
FHJKHKDH_00558 1.7e-135 recT L RecT family
FHJKHKDH_00559 4.4e-121 3.1.3.16 L DnaD domain protein
FHJKHKDH_00560 4.4e-163 xkdC L IstB-like ATP binding protein
FHJKHKDH_00562 2.6e-68 rusA L Endodeoxyribonuclease RusA
FHJKHKDH_00563 8.9e-30 yqaO S Phage-like element PBSX protein XtrA
FHJKHKDH_00565 1.1e-48 wecC 1.1.1.336 M ArpU family transcriptional regulator
FHJKHKDH_00569 2.8e-89 yrdC 3.5.1.19 Q Isochorismatase family
FHJKHKDH_00571 8.3e-99 yqaS L DNA packaging
FHJKHKDH_00572 1.4e-248 S phage terminase, large subunit
FHJKHKDH_00573 2.5e-286 yqbA S portal protein
FHJKHKDH_00574 1.3e-149 S Phage Mu protein F like protein
FHJKHKDH_00576 1.4e-112 yqbD 2.1.1.72 L Putative phage serine protease XkdF
FHJKHKDH_00577 1.9e-167 xkdG S Phage capsid family
FHJKHKDH_00578 1.2e-46 S YqbF, hypothetical protein domain
FHJKHKDH_00579 2.7e-67 S Protein of unknown function (DUF3199)
FHJKHKDH_00580 1.7e-63 yqbH S Domain of unknown function (DUF3599)
FHJKHKDH_00581 5.3e-84 S Bacteriophage HK97-gp10, putative tail-component
FHJKHKDH_00582 5.1e-75
FHJKHKDH_00583 1e-24
FHJKHKDH_00584 2.2e-252 xkdK S Phage tail sheath C-terminal domain
FHJKHKDH_00585 2.3e-75 xkdM S Phage tail tube protein
FHJKHKDH_00586 6.2e-68 S Phage XkdN-like tail assembly chaperone protein, TAC
FHJKHKDH_00587 0.0 xkdO L Transglycosylase SLT domain
FHJKHKDH_00588 2.2e-112 xkdP S Lysin motif
FHJKHKDH_00589 2.2e-42 qacC U Small Multidrug Resistance protein
FHJKHKDH_00590 1.2e-177 yqbQ 3.2.1.96 G NLP P60 protein
FHJKHKDH_00591 9.4e-32 xkdR S Protein of unknown function (DUF2577)
FHJKHKDH_00592 1.3e-70 xkdS S Protein of unknown function (DUF2634)
FHJKHKDH_00593 1.2e-186 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
FHJKHKDH_00594 7.4e-98 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
FHJKHKDH_00595 1e-36
FHJKHKDH_00596 2.3e-164
FHJKHKDH_00597 7.3e-42 xkdW S XkdW protein
FHJKHKDH_00598 1.3e-18
FHJKHKDH_00599 2.6e-158 xepA
FHJKHKDH_00600 6.4e-67 S Bacteriophage holin family
FHJKHKDH_00601 1.3e-129 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
FHJKHKDH_00602 3e-117 EGP Necrosis inducing protein (NPP1)
FHJKHKDH_00603 7.8e-82 S SMI1-KNR4 cell-wall
FHJKHKDH_00604 4.3e-298 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
FHJKHKDH_00606 5e-66 S response regulator aspartate phosphatase
FHJKHKDH_00608 3.5e-100 yrkC G Cupin domain
FHJKHKDH_00609 5.1e-21
FHJKHKDH_00610 1.6e-36 yrkD S protein conserved in bacteria
FHJKHKDH_00611 3.4e-80 yrkE O DsrE/DsrF/DrsH-like family
FHJKHKDH_00612 8.4e-55 P Rhodanese Homology Domain
FHJKHKDH_00613 5.6e-87 yrkF OP Belongs to the sulfur carrier protein TusA family
FHJKHKDH_00614 1.9e-57 perX S DsrE/DsrF-like family
FHJKHKDH_00615 4.5e-200 yrkH P Rhodanese Homology Domain
FHJKHKDH_00616 9.5e-33 yrkI O Belongs to the sulfur carrier protein TusA family
FHJKHKDH_00617 1.2e-111 yrkJ S membrane transporter protein
FHJKHKDH_00618 8.4e-149 yhjR 2.7.7.87 S Rubrerythrin
FHJKHKDH_00619 1.4e-112 ydfS S Protein of unknown function (DUF421)
FHJKHKDH_00622 3.5e-277 cisA2 L Recombinase
FHJKHKDH_00623 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FHJKHKDH_00624 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
FHJKHKDH_00625 2.3e-133 yqeB
FHJKHKDH_00626 4.2e-133 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
FHJKHKDH_00627 5.2e-19 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
FHJKHKDH_00628 6.7e-105 yqeD S SNARE associated Golgi protein
FHJKHKDH_00629 1.7e-131 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
FHJKHKDH_00630 1.8e-141 yqeF E GDSL-like Lipase/Acylhydrolase
FHJKHKDH_00632 5.3e-95 yqeG S hydrolase of the HAD superfamily
FHJKHKDH_00633 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
FHJKHKDH_00634 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FHJKHKDH_00635 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
FHJKHKDH_00636 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FHJKHKDH_00637 7.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
FHJKHKDH_00638 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
FHJKHKDH_00639 2.9e-139 yqeM Q Methyltransferase
FHJKHKDH_00640 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FHJKHKDH_00641 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
FHJKHKDH_00642 1.8e-104 comEB 3.5.4.12 F ComE operon protein 2
FHJKHKDH_00643 0.0 comEC S Competence protein ComEC
FHJKHKDH_00644 4.1e-15 S YqzM-like protein
FHJKHKDH_00645 5.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
FHJKHKDH_00646 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
FHJKHKDH_00647 1.5e-203 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FHJKHKDH_00648 1.5e-222 spoIIP M stage II sporulation protein P
FHJKHKDH_00649 7.2e-53 yqxA S Protein of unknown function (DUF3679)
FHJKHKDH_00650 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
FHJKHKDH_00651 7e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
FHJKHKDH_00652 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
FHJKHKDH_00653 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FHJKHKDH_00654 0.0 dnaK O Heat shock 70 kDa protein
FHJKHKDH_00655 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
FHJKHKDH_00656 4.6e-174 prmA J Methylates ribosomal protein L11
FHJKHKDH_00657 2.1e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
FHJKHKDH_00658 6.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
FHJKHKDH_00659 8.2e-158 yqeW P COG1283 Na phosphate symporter
FHJKHKDH_00660 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
FHJKHKDH_00661 2.5e-61 yqeY S Yqey-like protein
FHJKHKDH_00662 4.5e-228 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
FHJKHKDH_00663 9.6e-122 yqfA S UPF0365 protein
FHJKHKDH_00664 6e-25 yqfB
FHJKHKDH_00665 2.7e-45 yqfC S sporulation protein YqfC
FHJKHKDH_00666 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
FHJKHKDH_00667 1.1e-175 phoH T Phosphate starvation-inducible protein PhoH
FHJKHKDH_00669 0.0 yqfF S membrane-associated HD superfamily hydrolase
FHJKHKDH_00670 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FHJKHKDH_00671 1.6e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
FHJKHKDH_00672 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
FHJKHKDH_00673 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FHJKHKDH_00674 8.4e-19 S YqzL-like protein
FHJKHKDH_00675 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
FHJKHKDH_00676 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
FHJKHKDH_00677 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
FHJKHKDH_00678 4.5e-112 ccpN K CBS domain
FHJKHKDH_00679 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
FHJKHKDH_00680 4.5e-88 yaiI S Belongs to the UPF0178 family
FHJKHKDH_00681 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
FHJKHKDH_00682 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
FHJKHKDH_00683 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
FHJKHKDH_00684 6.1e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
FHJKHKDH_00685 1.9e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FHJKHKDH_00686 2.6e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FHJKHKDH_00687 2.9e-14 yqfQ S YqfQ-like protein
FHJKHKDH_00688 1.7e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
FHJKHKDH_00689 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FHJKHKDH_00690 2.1e-36 yqfT S Protein of unknown function (DUF2624)
FHJKHKDH_00691 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
FHJKHKDH_00692 4.2e-77 zur P Belongs to the Fur family
FHJKHKDH_00693 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
FHJKHKDH_00694 4.3e-62 yqfX S membrane
FHJKHKDH_00695 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FHJKHKDH_00696 1.2e-46 yqfZ M LysM domain
FHJKHKDH_00697 1.5e-130 yqgB S Protein of unknown function (DUF1189)
FHJKHKDH_00698 4e-73 yqgC S protein conserved in bacteria
FHJKHKDH_00699 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
FHJKHKDH_00700 2.5e-231 yqgE EGP Major facilitator superfamily
FHJKHKDH_00701 0.0 pbpA 3.4.16.4 M penicillin-binding protein
FHJKHKDH_00702 2e-150 pstS P Phosphate
FHJKHKDH_00703 7.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
FHJKHKDH_00704 4.4e-158 pstA P Phosphate transport system permease
FHJKHKDH_00705 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
FHJKHKDH_00706 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
FHJKHKDH_00707 7.3e-72 yqzC S YceG-like family
FHJKHKDH_00708 3.5e-50 yqzD
FHJKHKDH_00710 5.1e-201 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
FHJKHKDH_00711 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
FHJKHKDH_00712 2e-103 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FHJKHKDH_00713 2.5e-09 yqgO
FHJKHKDH_00714 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
FHJKHKDH_00715 4.3e-33 yqgQ S Protein conserved in bacteria
FHJKHKDH_00716 5.2e-181 glcK 2.7.1.2 G Glucokinase
FHJKHKDH_00717 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
FHJKHKDH_00718 2.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
FHJKHKDH_00719 3.9e-198 yqgU
FHJKHKDH_00720 6.9e-50 yqgV S Thiamine-binding protein
FHJKHKDH_00721 8.9e-23 yqgW S Protein of unknown function (DUF2759)
FHJKHKDH_00722 1.2e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
FHJKHKDH_00723 1.8e-37 yqgY S Protein of unknown function (DUF2626)
FHJKHKDH_00724 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
FHJKHKDH_00726 7e-150 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
FHJKHKDH_00727 7.5e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
FHJKHKDH_00728 7.2e-175 corA P Mg2 transporter protein
FHJKHKDH_00731 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FHJKHKDH_00732 2.3e-174 comGB NU COG1459 Type II secretory pathway, component PulF
FHJKHKDH_00733 5.2e-47 comGC U Required for transformation and DNA binding
FHJKHKDH_00734 7.7e-68 gspH NU protein transport across the cell outer membrane
FHJKHKDH_00735 1.3e-57 comGE
FHJKHKDH_00736 1.4e-33 comGF U Putative Competence protein ComGF
FHJKHKDH_00737 1.8e-44 S ComG operon protein 7
FHJKHKDH_00738 4.4e-25 yqzE S YqzE-like protein
FHJKHKDH_00739 7.3e-54 yqzG S Protein of unknown function (DUF3889)
FHJKHKDH_00740 9.2e-83 yqxM
FHJKHKDH_00741 1.7e-21 yqxM
FHJKHKDH_00742 1.9e-58 sipW 3.4.21.89 U Signal peptidase
FHJKHKDH_00743 2.5e-141 tasA S Cell division protein FtsN
FHJKHKDH_00744 1e-54 sinR K transcriptional
FHJKHKDH_00745 1.2e-24 sinI S Anti-repressor SinI
FHJKHKDH_00746 3.2e-152 yqhG S Bacterial protein YqhG of unknown function
FHJKHKDH_00747 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
FHJKHKDH_00748 5.3e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
FHJKHKDH_00749 1.7e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FHJKHKDH_00750 1e-284 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FHJKHKDH_00751 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
FHJKHKDH_00752 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
FHJKHKDH_00753 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
FHJKHKDH_00754 3.4e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
FHJKHKDH_00755 2.2e-61 yqhP
FHJKHKDH_00756 4e-173 yqhQ S Protein of unknown function (DUF1385)
FHJKHKDH_00757 2.3e-93 yqhR S Conserved membrane protein YqhR
FHJKHKDH_00758 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
FHJKHKDH_00759 3.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
FHJKHKDH_00760 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FHJKHKDH_00761 7.9e-37 yqhV S Protein of unknown function (DUF2619)
FHJKHKDH_00762 8.8e-170 spoIIIAA S stage III sporulation protein AA
FHJKHKDH_00763 1.1e-84 spoIIIAB S Stage III sporulation protein
FHJKHKDH_00764 7.6e-29 spoIIIAC S stage III sporulation protein AC
FHJKHKDH_00765 2.3e-58 spoIIIAD S Stage III sporulation protein AD
FHJKHKDH_00766 8.4e-197 spoIIIAE S stage III sporulation protein AE
FHJKHKDH_00767 1.2e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
FHJKHKDH_00768 3.6e-107 spoIIIAG S stage III sporulation protein AG
FHJKHKDH_00769 3.8e-90 spoIIIAH S SpoIIIAH-like protein
FHJKHKDH_00770 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
FHJKHKDH_00771 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
FHJKHKDH_00772 2.1e-67 yqhY S protein conserved in bacteria
FHJKHKDH_00773 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FHJKHKDH_00774 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FHJKHKDH_00775 1.9e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
FHJKHKDH_00776 1.5e-37 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
FHJKHKDH_00777 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
FHJKHKDH_00778 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FHJKHKDH_00779 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
FHJKHKDH_00780 1.7e-78 argR K Regulates arginine biosynthesis genes
FHJKHKDH_00781 4.2e-306 recN L May be involved in recombinational repair of damaged DNA
FHJKHKDH_00782 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
FHJKHKDH_00783 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
FHJKHKDH_00785 2.1e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
FHJKHKDH_00786 6e-27
FHJKHKDH_00787 1.2e-106 amiC 3.5.1.28 M Cell wall hydrolase autolysin
FHJKHKDH_00788 3.1e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
FHJKHKDH_00789 7.2e-217 mmgA 2.3.1.9 I Belongs to the thiolase family
FHJKHKDH_00790 1.2e-155 hbdA 1.1.1.157 I Dehydrogenase
FHJKHKDH_00791 1.3e-210 mmgC I acyl-CoA dehydrogenase
FHJKHKDH_00792 1.5e-208 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
FHJKHKDH_00793 9.1e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
FHJKHKDH_00794 3e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FHJKHKDH_00795 4e-34 yqzF S Protein of unknown function (DUF2627)
FHJKHKDH_00796 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
FHJKHKDH_00797 5.6e-153 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
FHJKHKDH_00798 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
FHJKHKDH_00799 2.7e-202 buk 2.7.2.7 C Belongs to the acetokinase family
FHJKHKDH_00800 3.7e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
FHJKHKDH_00801 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
FHJKHKDH_00802 5.1e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
FHJKHKDH_00803 2.6e-220 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
FHJKHKDH_00804 2.6e-152 bmrR K helix_turn_helix, mercury resistance
FHJKHKDH_00805 7.9e-208 norA EGP Major facilitator Superfamily
FHJKHKDH_00806 3.7e-165 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
FHJKHKDH_00807 9.3e-77 yqiW S Belongs to the UPF0403 family
FHJKHKDH_00808 1.5e-135 artP ET Belongs to the bacterial solute-binding protein 3 family
FHJKHKDH_00809 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
FHJKHKDH_00810 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
FHJKHKDH_00811 7.3e-175 yqjA S Putative aromatic acid exporter C-terminal domain
FHJKHKDH_00812 1.4e-98 yqjB S protein conserved in bacteria
FHJKHKDH_00814 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
FHJKHKDH_00815 4.4e-291 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
FHJKHKDH_00816 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
FHJKHKDH_00817 3.6e-142 yqjF S Uncharacterized conserved protein (COG2071)
FHJKHKDH_00818 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FHJKHKDH_00819 4.5e-24 yqzJ
FHJKHKDH_00820 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FHJKHKDH_00821 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FHJKHKDH_00822 1.6e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FHJKHKDH_00823 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
FHJKHKDH_00824 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
FHJKHKDH_00825 1.8e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
FHJKHKDH_00826 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
FHJKHKDH_00827 0.0 rocB E arginine degradation protein
FHJKHKDH_00828 1.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FHJKHKDH_00829 1.8e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
FHJKHKDH_00830 3.5e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
FHJKHKDH_00831 1.2e-260 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
FHJKHKDH_00832 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
FHJKHKDH_00833 3e-71 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
FHJKHKDH_00835 7e-223 yqjV G Major Facilitator Superfamily
FHJKHKDH_00837 4.5e-238 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FHJKHKDH_00838 1.7e-49 S YolD-like protein
FHJKHKDH_00839 3.6e-87 yqjY K acetyltransferase
FHJKHKDH_00840 3.8e-54 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
FHJKHKDH_00841 5.2e-195 yqkA K GrpB protein
FHJKHKDH_00842 2.8e-54 yqkB S Belongs to the HesB IscA family
FHJKHKDH_00843 9.4e-39 yqkC S Protein of unknown function (DUF2552)
FHJKHKDH_00844 2e-174 yqkD S COG1073 Hydrolases of the alpha beta superfamily
FHJKHKDH_00845 4e-14 yqkE S Protein of unknown function (DUF3886)
FHJKHKDH_00846 7.4e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
FHJKHKDH_00848 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
FHJKHKDH_00849 3e-223 yqxK 3.6.4.12 L DNA helicase
FHJKHKDH_00850 4.5e-58 ansR K Transcriptional regulator
FHJKHKDH_00851 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
FHJKHKDH_00852 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
FHJKHKDH_00853 3.1e-235 mleN C Na H antiporter
FHJKHKDH_00854 5.5e-242 mleA 1.1.1.38 C malic enzyme
FHJKHKDH_00855 2e-32 yqkK
FHJKHKDH_00856 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
FHJKHKDH_00857 2.4e-80 fur P Belongs to the Fur family
FHJKHKDH_00858 1.4e-36 S Protein of unknown function (DUF4227)
FHJKHKDH_00859 5.7e-166 xerD L recombinase XerD
FHJKHKDH_00860 1.1e-230 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
FHJKHKDH_00861 8.4e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FHJKHKDH_00862 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
FHJKHKDH_00863 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
FHJKHKDH_00864 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
FHJKHKDH_00865 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FHJKHKDH_00866 9.6e-112 spoVAA S Stage V sporulation protein AA
FHJKHKDH_00867 1e-67 spoVAB S Stage V sporulation protein AB
FHJKHKDH_00868 1.5e-77 spoVAC S stage V sporulation protein AC
FHJKHKDH_00869 9e-192 spoVAD I Stage V sporulation protein AD
FHJKHKDH_00870 2.2e-57 spoVAEB S stage V sporulation protein
FHJKHKDH_00871 1.4e-110 spoVAEA S stage V sporulation protein
FHJKHKDH_00872 1.4e-273 spoVAF EG Stage V sporulation protein AF
FHJKHKDH_00873 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
FHJKHKDH_00874 1.3e-149 ypuA S Secreted protein
FHJKHKDH_00875 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FHJKHKDH_00877 9.1e-16 S SNARE associated Golgi protein
FHJKHKDH_00878 6.6e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
FHJKHKDH_00879 3.5e-97 sipT 3.4.21.89 U Belongs to the peptidase S26 family
FHJKHKDH_00880 6e-55 ypuD
FHJKHKDH_00881 1.3e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FHJKHKDH_00882 1.7e-114 ribE 2.5.1.9 H Riboflavin synthase
FHJKHKDH_00883 1.9e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FHJKHKDH_00884 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
FHJKHKDH_00885 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FHJKHKDH_00886 4.6e-91 ypuF S Domain of unknown function (DUF309)
FHJKHKDH_00887 6.4e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FHJKHKDH_00888 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FHJKHKDH_00889 7.6e-97 ypuI S Protein of unknown function (DUF3907)
FHJKHKDH_00890 8.9e-212 dacB 3.4.16.4 M Belongs to the peptidase S11 family
FHJKHKDH_00891 3.5e-103 spmA S Spore maturation protein
FHJKHKDH_00892 1.9e-87 spmB S Spore maturation protein
FHJKHKDH_00893 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
FHJKHKDH_00894 4.8e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
FHJKHKDH_00895 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
FHJKHKDH_00896 6.7e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
FHJKHKDH_00897 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FHJKHKDH_00898 0.0 resE 2.7.13.3 T Histidine kinase
FHJKHKDH_00899 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
FHJKHKDH_00900 8.3e-199 rsiX
FHJKHKDH_00901 5.9e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
FHJKHKDH_00902 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FHJKHKDH_00903 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FHJKHKDH_00904 4.7e-41 fer C Ferredoxin
FHJKHKDH_00905 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
FHJKHKDH_00906 3e-284 recQ 3.6.4.12 L DNA helicase
FHJKHKDH_00907 2.2e-100 ypbD S metal-dependent membrane protease
FHJKHKDH_00908 2.9e-75 ypbE M Lysin motif
FHJKHKDH_00909 2.8e-81 ypbF S Protein of unknown function (DUF2663)
FHJKHKDH_00910 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
FHJKHKDH_00911 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
FHJKHKDH_00912 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
FHJKHKDH_00913 1.3e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
FHJKHKDH_00914 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
FHJKHKDH_00915 6.5e-149 sleB 3.5.1.28 M Spore cortex-lytic enzyme
FHJKHKDH_00916 1.9e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
FHJKHKDH_00917 3.9e-111 ypfA M Flagellar protein YcgR
FHJKHKDH_00918 2.4e-23 S Family of unknown function (DUF5359)
FHJKHKDH_00919 6.8e-111 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
FHJKHKDH_00920 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
FHJKHKDH_00921 1.2e-183 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
FHJKHKDH_00922 8e-08 S YpzI-like protein
FHJKHKDH_00923 2.3e-102 yphA
FHJKHKDH_00924 2.5e-161 seaA S YIEGIA protein
FHJKHKDH_00925 2.3e-27 ypzH
FHJKHKDH_00926 1.5e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
FHJKHKDH_00927 5.6e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
FHJKHKDH_00928 1.6e-18 yphE S Protein of unknown function (DUF2768)
FHJKHKDH_00929 3.9e-136 yphF
FHJKHKDH_00930 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FHJKHKDH_00931 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
FHJKHKDH_00932 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
FHJKHKDH_00933 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
FHJKHKDH_00934 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
FHJKHKDH_00935 1.5e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
FHJKHKDH_00936 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
FHJKHKDH_00937 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
FHJKHKDH_00938 1.1e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
FHJKHKDH_00939 1.2e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FHJKHKDH_00940 6.5e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FHJKHKDH_00941 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
FHJKHKDH_00942 3.1e-292 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FHJKHKDH_00943 2.7e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FHJKHKDH_00944 1.1e-112 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
FHJKHKDH_00945 6.7e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
FHJKHKDH_00946 4.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
FHJKHKDH_00947 1.2e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
FHJKHKDH_00948 1.4e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FHJKHKDH_00949 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
FHJKHKDH_00950 7.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
FHJKHKDH_00951 2.7e-233 S COG0457 FOG TPR repeat
FHJKHKDH_00952 2.8e-99 ypiB S Belongs to the UPF0302 family
FHJKHKDH_00953 4.2e-77 ypiF S Protein of unknown function (DUF2487)
FHJKHKDH_00954 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
FHJKHKDH_00955 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
FHJKHKDH_00956 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
FHJKHKDH_00957 4.4e-98 ypjA S membrane
FHJKHKDH_00958 6.1e-143 ypjB S sporulation protein
FHJKHKDH_00959 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
FHJKHKDH_00960 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
FHJKHKDH_00961 4.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
FHJKHKDH_00962 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
FHJKHKDH_00963 1.7e-128 bshB1 S proteins, LmbE homologs
FHJKHKDH_00964 1.3e-207 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
FHJKHKDH_00965 7.8e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
FHJKHKDH_00966 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
FHJKHKDH_00967 1.3e-148 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
FHJKHKDH_00968 1e-156 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FHJKHKDH_00969 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FHJKHKDH_00970 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
FHJKHKDH_00971 1.9e-22 ypmA S Protein of unknown function (DUF4264)
FHJKHKDH_00972 3.4e-80 ypmB S protein conserved in bacteria
FHJKHKDH_00973 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
FHJKHKDH_00974 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
FHJKHKDH_00975 1.3e-128 dnaD L DNA replication protein DnaD
FHJKHKDH_00976 1.4e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FHJKHKDH_00977 1.8e-92 ypoC
FHJKHKDH_00978 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
FHJKHKDH_00979 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
FHJKHKDH_00980 7e-186 yppC S Protein of unknown function (DUF2515)
FHJKHKDH_00983 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
FHJKHKDH_00984 4.4e-07 S YppF-like protein
FHJKHKDH_00985 1.2e-48 yppG S YppG-like protein
FHJKHKDH_00986 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
FHJKHKDH_00987 1.6e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
FHJKHKDH_00988 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
FHJKHKDH_00989 7.3e-236 yprB L RNase_H superfamily
FHJKHKDH_00990 8.2e-91 ypsA S Belongs to the UPF0398 family
FHJKHKDH_00991 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
FHJKHKDH_00992 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
FHJKHKDH_00994 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
FHJKHKDH_00995 5.7e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FHJKHKDH_00996 4.1e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FHJKHKDH_00997 7.4e-186 ptxS K transcriptional
FHJKHKDH_00998 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
FHJKHKDH_00999 4.6e-103 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
FHJKHKDH_01000 1.5e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
FHJKHKDH_01001 4.6e-293 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FHJKHKDH_01002 1.1e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
FHJKHKDH_01003 1.5e-226 pbuX F xanthine
FHJKHKDH_01004 1.5e-205 bcsA Q Naringenin-chalcone synthase
FHJKHKDH_01005 5.1e-87 ypbQ S protein conserved in bacteria
FHJKHKDH_01006 0.0 ypbR S Dynamin family
FHJKHKDH_01007 1e-38 ypbS S Protein of unknown function (DUF2533)
FHJKHKDH_01008 2e-07
FHJKHKDH_01009 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
FHJKHKDH_01011 2.7e-67 rnhA 3.1.26.4 L Ribonuclease
FHJKHKDH_01012 2.9e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FHJKHKDH_01013 1.8e-134 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
FHJKHKDH_01014 2.6e-27 ypeQ S Zinc-finger
FHJKHKDH_01015 4.7e-31 S Protein of unknown function (DUF2564)
FHJKHKDH_01016 3.8e-16 degR
FHJKHKDH_01017 7.9e-31 cspD K Cold-shock protein
FHJKHKDH_01018 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
FHJKHKDH_01019 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FHJKHKDH_01020 2.6e-88 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
FHJKHKDH_01021 5.4e-107 ypgQ S phosphohydrolase
FHJKHKDH_01022 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
FHJKHKDH_01023 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
FHJKHKDH_01024 1.7e-75 yphP S Belongs to the UPF0403 family
FHJKHKDH_01025 1.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
FHJKHKDH_01026 7.8e-114 ypjP S YpjP-like protein
FHJKHKDH_01027 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
FHJKHKDH_01028 4.3e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FHJKHKDH_01029 7.9e-96 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FHJKHKDH_01030 7.4e-112 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
FHJKHKDH_01031 4.2e-110 hlyIII S protein, Hemolysin III
FHJKHKDH_01032 1.6e-185 pspF K Transcriptional regulator
FHJKHKDH_01033 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FHJKHKDH_01034 3.1e-40 ypmP S Protein of unknown function (DUF2535)
FHJKHKDH_01035 3.2e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
FHJKHKDH_01036 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
FHJKHKDH_01037 5e-99 ypmS S protein conserved in bacteria
FHJKHKDH_01038 5.5e-29 ypmT S Uncharacterized ympT
FHJKHKDH_01039 1e-222 mepA V MATE efflux family protein
FHJKHKDH_01040 1.6e-70 ypoP K transcriptional
FHJKHKDH_01041 1.3e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FHJKHKDH_01042 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
FHJKHKDH_01043 1.3e-124 4.2.1.115 GM Polysaccharide biosynthesis protein
FHJKHKDH_01044 5.8e-211 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
FHJKHKDH_01045 4.1e-186 cgeB S Spore maturation protein
FHJKHKDH_01046 1.5e-65 cgeA
FHJKHKDH_01047 3.5e-38 cgeC
FHJKHKDH_01048 1.1e-255 cgeD M maturation of the outermost layer of the spore
FHJKHKDH_01049 4.1e-144 yiiD K acetyltransferase
FHJKHKDH_01051 3.4e-247 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FHJKHKDH_01052 7.1e-124 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FHJKHKDH_01053 2.8e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
FHJKHKDH_01054 7.9e-257 yodQ 3.5.1.16 E Acetylornithine deacetylase
FHJKHKDH_01055 7.9e-154 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
FHJKHKDH_01056 5.1e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
FHJKHKDH_01057 8.3e-47 yokU S YokU-like protein, putative antitoxin
FHJKHKDH_01058 1.4e-36 yozE S Belongs to the UPF0346 family
FHJKHKDH_01059 1.6e-123 yodN
FHJKHKDH_01061 2.8e-24 yozD S YozD-like protein
FHJKHKDH_01062 3.3e-104 yodM 3.6.1.27 I Acid phosphatase homologues
FHJKHKDH_01063 3.6e-54 yodL S YodL-like
FHJKHKDH_01064 5.3e-09
FHJKHKDH_01065 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
FHJKHKDH_01066 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
FHJKHKDH_01067 5.2e-24 yodI
FHJKHKDH_01068 6.3e-128 yodH Q Methyltransferase
FHJKHKDH_01069 1.8e-251 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
FHJKHKDH_01070 4e-265 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FHJKHKDH_01071 6.2e-28 S Protein of unknown function (DUF3311)
FHJKHKDH_01072 3.2e-172 yodE E COG0346 Lactoylglutathione lyase and related lyases
FHJKHKDH_01073 1.2e-111 mhqD S Carboxylesterase
FHJKHKDH_01074 1.4e-107 yodC C nitroreductase
FHJKHKDH_01075 4.4e-55 yodB K transcriptional
FHJKHKDH_01076 4.7e-64 yodA S tautomerase
FHJKHKDH_01077 1.3e-206 gntP EG COG2610 H gluconate symporter and related permeases
FHJKHKDH_01078 2.6e-09
FHJKHKDH_01079 5.7e-56 yozR S COG0071 Molecular chaperone (small heat shock protein)
FHJKHKDH_01080 3.9e-162 rarD S -transporter
FHJKHKDH_01081 4.3e-43
FHJKHKDH_01082 2.2e-60 yojF S Protein of unknown function (DUF1806)
FHJKHKDH_01083 2.1e-125 yojG S deacetylase
FHJKHKDH_01084 3.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
FHJKHKDH_01085 1.6e-244 norM V Multidrug efflux pump
FHJKHKDH_01087 4.1e-107 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FHJKHKDH_01088 4.1e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
FHJKHKDH_01089 7.9e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
FHJKHKDH_01090 1.7e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FHJKHKDH_01091 5.5e-161 yojN S ATPase family associated with various cellular activities (AAA)
FHJKHKDH_01092 0.0 yojO P Von Willebrand factor
FHJKHKDH_01093 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
FHJKHKDH_01094 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
FHJKHKDH_01095 1.2e-166 yocS S -transporter
FHJKHKDH_01096 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
FHJKHKDH_01097 6e-165 sodA 1.15.1.1 P Superoxide dismutase
FHJKHKDH_01098 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
FHJKHKDH_01099 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
FHJKHKDH_01100 2.7e-31 yozC
FHJKHKDH_01101 4.2e-56 yozO S Bacterial PH domain
FHJKHKDH_01102 1.9e-36 yocN
FHJKHKDH_01103 1.1e-40 yozN
FHJKHKDH_01104 2.4e-86 yocM O Belongs to the small heat shock protein (HSP20) family
FHJKHKDH_01105 2e-30
FHJKHKDH_01106 6.4e-54 yocL
FHJKHKDH_01107 7.4e-83 dksA T general stress protein
FHJKHKDH_01108 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FHJKHKDH_01109 0.0 recQ 3.6.4.12 L DNA helicase
FHJKHKDH_01110 2.1e-112 yocH CBM50 M COG1388 FOG LysM repeat
FHJKHKDH_01111 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FHJKHKDH_01112 7.1e-198 desK 2.7.13.3 T Histidine kinase
FHJKHKDH_01113 5.3e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
FHJKHKDH_01114 1.1e-186 yocD 3.4.17.13 V peptidase S66
FHJKHKDH_01115 1.6e-93 yocC
FHJKHKDH_01116 2.1e-143
FHJKHKDH_01117 1.5e-92 yozB S membrane
FHJKHKDH_01118 2.4e-108 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
FHJKHKDH_01119 1e-51 czrA K transcriptional
FHJKHKDH_01120 1.4e-93 yobW
FHJKHKDH_01121 1.4e-175 yobV K WYL domain
FHJKHKDH_01122 5.4e-86 yobU K Bacterial transcription activator, effector binding domain
FHJKHKDH_01123 2.1e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
FHJKHKDH_01124 3.3e-98 yobS K Transcriptional regulator
FHJKHKDH_01125 2.2e-142 yobR 2.3.1.1 J FR47-like protein
FHJKHKDH_01126 6.5e-136 yobQ K helix_turn_helix, arabinose operon control protein
FHJKHKDH_01127 1.4e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
FHJKHKDH_01128 1.9e-275 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
FHJKHKDH_01129 5.1e-91 yokH G SMI1 / KNR4 family
FHJKHKDH_01130 6.5e-10 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
FHJKHKDH_01131 1.5e-19
FHJKHKDH_01133 3.3e-44
FHJKHKDH_01135 4.2e-33 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FHJKHKDH_01136 1.5e-158 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FHJKHKDH_01138 2.4e-206 S aspartate phosphatase
FHJKHKDH_01146 5.2e-61 J tRNA cytidylyltransferase activity
FHJKHKDH_01147 9.1e-54 S Tetratricopeptide repeat
FHJKHKDH_01151 4.6e-11 ywlA S Uncharacterised protein family (UPF0715)
FHJKHKDH_01156 9.5e-50 FG Scavenger mRNA decapping enzyme C-term binding
FHJKHKDH_01159 2.4e-56 K Helix-turn-helix
FHJKHKDH_01160 1.3e-35 S TM2 domain
FHJKHKDH_01161 6.9e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
FHJKHKDH_01162 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
FHJKHKDH_01165 8.2e-168 bla 3.5.2.6 V beta-lactamase
FHJKHKDH_01166 2.1e-114 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
FHJKHKDH_01167 2.7e-76 yoaW
FHJKHKDH_01168 2.5e-158 yijE EG EamA-like transporter family
FHJKHKDH_01169 4.3e-158 yoaU K LysR substrate binding domain
FHJKHKDH_01170 1.4e-147 yoaT S Protein of unknown function (DUF817)
FHJKHKDH_01171 4.4e-30 yozG K Transcriptional regulator
FHJKHKDH_01172 7.3e-75 yoaS S Protein of unknown function (DUF2975)
FHJKHKDH_01173 7.1e-172 yoaR V vancomycin resistance protein
FHJKHKDH_01174 1.5e-86
FHJKHKDH_01176 2.7e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
FHJKHKDH_01177 3.4e-143 yoaP 3.1.3.18 K YoaP-like
FHJKHKDH_01179 1e-231 oxdC 4.1.1.2 G Oxalate decarboxylase
FHJKHKDH_01182 3.2e-132 yoqW S Belongs to the SOS response-associated peptidase family
FHJKHKDH_01183 4.3e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
FHJKHKDH_01184 2.3e-111 yoaK S Membrane
FHJKHKDH_01185 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
FHJKHKDH_01186 2.5e-280 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
FHJKHKDH_01187 1.1e-173 mcpU NT methyl-accepting chemotaxis protein
FHJKHKDH_01188 7.7e-35 S Protein of unknown function (DUF4025)
FHJKHKDH_01189 2.6e-13
FHJKHKDH_01192 1.1e-33 yoaF
FHJKHKDH_01193 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FHJKHKDH_01194 1.5e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FHJKHKDH_01195 9.1e-278 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
FHJKHKDH_01196 4e-234 yoaB EGP Major facilitator Superfamily
FHJKHKDH_01197 1.9e-126 3.1.1.3 I Lipase (class 3)
FHJKHKDH_01198 1.7e-241 S Arylsulfotransferase (ASST)
FHJKHKDH_01199 4.3e-92 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
FHJKHKDH_01200 5.5e-133 yoxB
FHJKHKDH_01201 3.7e-40 yoxC S Bacterial protein of unknown function (DUF948)
FHJKHKDH_01202 1e-120 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
FHJKHKDH_01203 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
FHJKHKDH_01204 1.3e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FHJKHKDH_01205 6e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FHJKHKDH_01206 7.8e-155 gltC K Transcriptional regulator
FHJKHKDH_01207 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
FHJKHKDH_01208 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
FHJKHKDH_01209 1.9e-186 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
FHJKHKDH_01210 2.5e-158 gltR1 K Transcriptional regulator
FHJKHKDH_01211 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
FHJKHKDH_01212 3e-34 yoeD G Helix-turn-helix domain
FHJKHKDH_01213 2.2e-96 L Integrase
FHJKHKDH_01215 3.1e-98 yoeB S IseA DL-endopeptidase inhibitor
FHJKHKDH_01216 5.6e-245 yoeA V MATE efflux family protein
FHJKHKDH_01217 1.8e-189 yoxA 5.1.3.3 G Aldose 1-epimerase
FHJKHKDH_01218 4.4e-272 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
FHJKHKDH_01219 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FHJKHKDH_01220 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FHJKHKDH_01221 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FHJKHKDH_01222 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FHJKHKDH_01223 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
FHJKHKDH_01224 1.1e-63 yngL S Protein of unknown function (DUF1360)
FHJKHKDH_01225 5.9e-304 yngK T Glycosyl hydrolase-like 10
FHJKHKDH_01227 5.4e-209 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
FHJKHKDH_01228 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
FHJKHKDH_01229 9.5e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
FHJKHKDH_01230 8.7e-31 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
FHJKHKDH_01231 3.4e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
FHJKHKDH_01232 9.2e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
FHJKHKDH_01233 7.7e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
FHJKHKDH_01234 1.2e-232 nrnB S phosphohydrolase (DHH superfamily)
FHJKHKDH_01235 5.5e-104 yngC S membrane-associated protein
FHJKHKDH_01236 1.3e-162 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
FHJKHKDH_01237 2.2e-78 yngA S membrane
FHJKHKDH_01238 6.6e-295 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
FHJKHKDH_01239 1.8e-250 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
FHJKHKDH_01241 2.4e-294 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
FHJKHKDH_01242 9e-251 agcS E Sodium alanine symporter
FHJKHKDH_01243 1.3e-57 ynfC
FHJKHKDH_01244 2.3e-12
FHJKHKDH_01245 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
FHJKHKDH_01246 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
FHJKHKDH_01247 6.6e-69 yccU S CoA-binding protein
FHJKHKDH_01248 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
FHJKHKDH_01249 4.1e-49 yneR S Belongs to the HesB IscA family
FHJKHKDH_01250 2.2e-53 yneQ
FHJKHKDH_01251 2.7e-73 yneP S Thioesterase-like superfamily
FHJKHKDH_01252 3.9e-35 tlp S Belongs to the Tlp family
FHJKHKDH_01253 3.1e-08 sspN S Small acid-soluble spore protein N family
FHJKHKDH_01255 5.9e-91 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FHJKHKDH_01256 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FHJKHKDH_01257 2.2e-14 sspO S Belongs to the SspO family
FHJKHKDH_01258 3.9e-19 sspP S Belongs to the SspP family
FHJKHKDH_01259 5.9e-64 hspX O Spore coat protein
FHJKHKDH_01260 7.2e-74 yneK S Protein of unknown function (DUF2621)
FHJKHKDH_01261 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
FHJKHKDH_01262 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
FHJKHKDH_01263 7.1e-127 ccdA O cytochrome c biogenesis protein
FHJKHKDH_01264 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
FHJKHKDH_01265 1.8e-28 yneF S UPF0154 protein
FHJKHKDH_01266 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
FHJKHKDH_01267 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FHJKHKDH_01268 1.3e-32 ynzC S UPF0291 protein
FHJKHKDH_01269 4.5e-112 yneB L resolvase
FHJKHKDH_01270 9.9e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
FHJKHKDH_01271 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FHJKHKDH_01272 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
FHJKHKDH_01273 5.8e-74 yndM S Protein of unknown function (DUF2512)
FHJKHKDH_01274 4.7e-137 yndL S Replication protein
FHJKHKDH_01276 2.3e-311 yndJ S YndJ-like protein
FHJKHKDH_01277 3.2e-115 yndH S Domain of unknown function (DUF4166)
FHJKHKDH_01278 7.7e-154 yndG S DoxX-like family
FHJKHKDH_01279 1.2e-219 gerLC S Spore germination protein
FHJKHKDH_01280 1.7e-196 gerAB U Spore germination
FHJKHKDH_01281 5.8e-283 gerAA EG Spore germination protein
FHJKHKDH_01284 5.8e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
FHJKHKDH_01285 1.8e-71
FHJKHKDH_01286 7.9e-25 tatA U protein secretion
FHJKHKDH_01289 3.7e-134 S Domain of unknown function, YrpD
FHJKHKDH_01291 8.6e-164 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FHJKHKDH_01294 5.2e-15
FHJKHKDH_01295 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
FHJKHKDH_01296 5.9e-82 yncE S Protein of unknown function (DUF2691)
FHJKHKDH_01297 2.2e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FHJKHKDH_01298 6.1e-255 iolT EGP Major facilitator Superfamily
FHJKHKDH_01299 6.4e-111 yokF 3.1.31.1 L RNA catabolic process
FHJKHKDH_01300 9.6e-291 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
FHJKHKDH_01301 5.8e-263 xylA 5.3.1.5 G Belongs to the xylose isomerase family
FHJKHKDH_01302 1.1e-212 xylR GK ROK family
FHJKHKDH_01303 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
FHJKHKDH_01304 6.7e-254 xynT G MFS/sugar transport protein
FHJKHKDH_01305 2.4e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
FHJKHKDH_01307 8.8e-47 ynaF
FHJKHKDH_01308 7.1e-110 ynaE S Domain of unknown function (DUF3885)
FHJKHKDH_01309 1e-21 K Cro/C1-type HTH DNA-binding domain
FHJKHKDH_01310 4.7e-08 S Uncharacterised protein family (UPF0715)
FHJKHKDH_01311 2.9e-72 S CAAX protease self-immunity
FHJKHKDH_01313 1.3e-96 ynaD J Acetyltransferase (GNAT) domain
FHJKHKDH_01315 2.9e-217 sumf2 2.1.1.295 GT2,GT4 H N-terminal domain of galactosyltransferase
FHJKHKDH_01316 2.2e-191 M COG0463 Glycosyltransferases involved in cell wall biogenesis
FHJKHKDH_01317 4.2e-119 H Methionine biosynthesis protein MetW
FHJKHKDH_01318 2.4e-92 M Glycosyltransferase like family
FHJKHKDH_01325 2e-08
FHJKHKDH_01329 7.7e-143 spo0M S COG4326 Sporulation control protein
FHJKHKDH_01330 1.2e-26
FHJKHKDH_01331 1.6e-131 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
FHJKHKDH_01332 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FHJKHKDH_01333 4.5e-263 ygaK C Berberine and berberine like
FHJKHKDH_01335 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
FHJKHKDH_01336 3e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
FHJKHKDH_01337 1.6e-169 ssuA M Sulfonate ABC transporter
FHJKHKDH_01338 4.2e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
FHJKHKDH_01339 2e-216 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
FHJKHKDH_01341 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FHJKHKDH_01342 4.1e-78 ygaO
FHJKHKDH_01343 4.4e-29 K Transcriptional regulator
FHJKHKDH_01345 7.9e-114 yhzB S B3/4 domain
FHJKHKDH_01346 2.3e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FHJKHKDH_01347 2.4e-175 yhbB S Putative amidase domain
FHJKHKDH_01348 2.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
FHJKHKDH_01349 2.7e-109 yhbD K Protein of unknown function (DUF4004)
FHJKHKDH_01350 1e-64 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
FHJKHKDH_01351 9.4e-71 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
FHJKHKDH_01352 0.0 prkA T Ser protein kinase
FHJKHKDH_01353 2.5e-225 yhbH S Belongs to the UPF0229 family
FHJKHKDH_01354 2.2e-76 yhbI K DNA-binding transcription factor activity
FHJKHKDH_01355 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
FHJKHKDH_01356 3.1e-271 yhcA EGP Major facilitator Superfamily
FHJKHKDH_01357 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
FHJKHKDH_01358 2.8e-37 yhcC
FHJKHKDH_01359 4.6e-55
FHJKHKDH_01360 1.9e-59 yhcF K Transcriptional regulator
FHJKHKDH_01361 4e-122 yhcG V ABC transporter, ATP-binding protein
FHJKHKDH_01362 6.5e-165 yhcH V ABC transporter, ATP-binding protein
FHJKHKDH_01363 8.7e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
FHJKHKDH_01364 1e-30 cspB K Cold-shock protein
FHJKHKDH_01365 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
FHJKHKDH_01366 3.4e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
FHJKHKDH_01367 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
FHJKHKDH_01368 2.9e-41 yhcM
FHJKHKDH_01369 3.5e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
FHJKHKDH_01370 7.1e-154 yhcP
FHJKHKDH_01371 5.2e-100 yhcQ M Spore coat protein
FHJKHKDH_01372 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
FHJKHKDH_01373 6e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
FHJKHKDH_01374 3e-170 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
FHJKHKDH_01375 9.3e-68 yhcU S Family of unknown function (DUF5365)
FHJKHKDH_01376 9.9e-68 yhcV S COG0517 FOG CBS domain
FHJKHKDH_01377 6e-120 yhcW 5.4.2.6 S hydrolase
FHJKHKDH_01378 6.6e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
FHJKHKDH_01379 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FHJKHKDH_01380 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FHJKHKDH_01381 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
FHJKHKDH_01382 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FHJKHKDH_01383 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FHJKHKDH_01384 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
FHJKHKDH_01385 2.6e-211 yhcY 2.7.13.3 T Histidine kinase
FHJKHKDH_01386 2.1e-109 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FHJKHKDH_01387 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
FHJKHKDH_01388 1.2e-38 yhdB S YhdB-like protein
FHJKHKDH_01389 4.8e-54 yhdC S Protein of unknown function (DUF3889)
FHJKHKDH_01390 9e-185 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
FHJKHKDH_01391 1e-75 nsrR K Transcriptional regulator
FHJKHKDH_01392 1.5e-238 ygxB M Conserved TM helix
FHJKHKDH_01393 2.1e-276 ycgB S Stage V sporulation protein R
FHJKHKDH_01394 8.3e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
FHJKHKDH_01395 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
FHJKHKDH_01396 3.8e-162 citR K Transcriptional regulator
FHJKHKDH_01397 1.5e-203 citA 2.3.3.1 C Belongs to the citrate synthase family
FHJKHKDH_01398 7.8e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FHJKHKDH_01399 3.4e-250 yhdG E amino acid
FHJKHKDH_01400 5.7e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
FHJKHKDH_01401 3.3e-269 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
FHJKHKDH_01402 4.5e-76 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FHJKHKDH_01403 8.1e-45 yhdK S Sigma-M inhibitor protein
FHJKHKDH_01404 2.5e-200 yhdL S Sigma factor regulator N-terminal
FHJKHKDH_01405 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
FHJKHKDH_01406 2.6e-191 yhdN C Aldo keto reductase
FHJKHKDH_01407 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
FHJKHKDH_01408 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
FHJKHKDH_01409 4.1e-74 cueR K transcriptional
FHJKHKDH_01410 3.3e-222 yhdR 2.6.1.1 E Aminotransferase
FHJKHKDH_01411 3.9e-246 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
FHJKHKDH_01412 4.9e-44 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FHJKHKDH_01413 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FHJKHKDH_01414 3.3e-135 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
FHJKHKDH_01416 6.6e-204 yhdY M Mechanosensitive ion channel
FHJKHKDH_01417 1.2e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
FHJKHKDH_01418 1.7e-151 yheN G deacetylase
FHJKHKDH_01419 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
FHJKHKDH_01420 1.2e-231 nhaC C Na H antiporter
FHJKHKDH_01421 3.4e-84 nhaX T Belongs to the universal stress protein A family
FHJKHKDH_01422 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
FHJKHKDH_01423 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
FHJKHKDH_01424 3.7e-111 yheG GM NAD(P)H-binding
FHJKHKDH_01425 6.3e-28 sspB S spore protein
FHJKHKDH_01426 1.3e-36 yheE S Family of unknown function (DUF5342)
FHJKHKDH_01427 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
FHJKHKDH_01428 4.3e-216 yheC HJ YheC/D like ATP-grasp
FHJKHKDH_01429 1.4e-201 yheB S Belongs to the UPF0754 family
FHJKHKDH_01430 9.5e-48 yheA S Belongs to the UPF0342 family
FHJKHKDH_01431 2e-205 yhaZ L DNA alkylation repair enzyme
FHJKHKDH_01432 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
FHJKHKDH_01433 6.7e-292 hemZ H coproporphyrinogen III oxidase
FHJKHKDH_01434 3.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
FHJKHKDH_01435 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
FHJKHKDH_01437 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
FHJKHKDH_01438 1.1e-26 S YhzD-like protein
FHJKHKDH_01439 5.7e-166 yhaQ S ABC transporter, ATP-binding protein
FHJKHKDH_01440 2.7e-214 yhaP CP COG1668 ABC-type Na efflux pump, permease component
FHJKHKDH_01441 2.8e-224 yhaO L DNA repair exonuclease
FHJKHKDH_01442 0.0 yhaN L AAA domain
FHJKHKDH_01443 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
FHJKHKDH_01444 1.6e-21 yhaL S Sporulation protein YhaL
FHJKHKDH_01445 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
FHJKHKDH_01446 8.7e-90 yhaK S Putative zincin peptidase
FHJKHKDH_01447 1.3e-54 yhaI S Protein of unknown function (DUF1878)
FHJKHKDH_01448 1e-113 hpr K Negative regulator of protease production and sporulation
FHJKHKDH_01449 7e-39 yhaH S YtxH-like protein
FHJKHKDH_01450 3.6e-80 trpP S Tryptophan transporter TrpP
FHJKHKDH_01451 2.4e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FHJKHKDH_01452 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
FHJKHKDH_01453 4.6e-137 ecsA V transporter (ATP-binding protein)
FHJKHKDH_01454 5.4e-215 ecsB U ABC transporter
FHJKHKDH_01455 3.1e-114 ecsC S EcsC protein family
FHJKHKDH_01456 9.2e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
FHJKHKDH_01457 1.1e-245 yhfA C membrane
FHJKHKDH_01458 2.6e-34 1.15.1.2 C Rubrerythrin
FHJKHKDH_01459 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
FHJKHKDH_01460 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
FHJKHKDH_01461 4.5e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FHJKHKDH_01462 3.1e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
FHJKHKDH_01463 2e-266 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FHJKHKDH_01464 2.4e-101 yhgD K Transcriptional regulator
FHJKHKDH_01465 3.8e-238 yhgE S YhgE Pip N-terminal domain protein
FHJKHKDH_01466 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FHJKHKDH_01467 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
FHJKHKDH_01468 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
FHJKHKDH_01469 1.4e-71 3.4.13.21 S ASCH
FHJKHKDH_01470 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
FHJKHKDH_01471 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
FHJKHKDH_01472 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
FHJKHKDH_01473 1.9e-110 yhfK GM NmrA-like family
FHJKHKDH_01474 2e-299 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
FHJKHKDH_01475 7.4e-65 yhfM
FHJKHKDH_01476 9.2e-242 yhfN 3.4.24.84 O Peptidase M48
FHJKHKDH_01477 4.7e-197 aprE 3.4.21.62 O Belongs to the peptidase S8 family
FHJKHKDH_01478 2.1e-76 VY92_01935 K acetyltransferase
FHJKHKDH_01479 1.2e-180 yhfP 1.1.1.1 C Quinone oxidoreductase
FHJKHKDH_01480 4.3e-159 yfmC M Periplasmic binding protein
FHJKHKDH_01481 7.1e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
FHJKHKDH_01482 3.8e-196 vraB 2.3.1.9 I Belongs to the thiolase family
FHJKHKDH_01483 2.8e-271 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
FHJKHKDH_01484 5e-91 bioY S BioY family
FHJKHKDH_01485 4.9e-182 hemAT NT chemotaxis protein
FHJKHKDH_01486 1.6e-301 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
FHJKHKDH_01487 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FHJKHKDH_01488 1.3e-32 yhzC S IDEAL
FHJKHKDH_01489 9.3e-109 comK K Competence transcription factor
FHJKHKDH_01490 1.1e-167 IQ Enoyl-(Acyl carrier protein) reductase
FHJKHKDH_01491 3.9e-41 yhjA S Excalibur calcium-binding domain
FHJKHKDH_01492 3.4e-264 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FHJKHKDH_01493 4.5e-26 yhjC S Protein of unknown function (DUF3311)
FHJKHKDH_01494 2.5e-59 yhjD
FHJKHKDH_01495 9.1e-110 yhjE S SNARE associated Golgi protein
FHJKHKDH_01496 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
FHJKHKDH_01497 1.1e-286 yhjG CH FAD binding domain
FHJKHKDH_01498 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
FHJKHKDH_01499 6.9e-215 glcP G Major Facilitator Superfamily
FHJKHKDH_01500 1.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
FHJKHKDH_01501 1.8e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
FHJKHKDH_01502 4.4e-255 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
FHJKHKDH_01503 1.6e-188 yhjM 5.1.1.1 K Transcriptional regulator
FHJKHKDH_01504 4.2e-201 abrB S membrane
FHJKHKDH_01505 7.6e-214 EGP Transmembrane secretion effector
FHJKHKDH_01506 0.0 S Sugar transport-related sRNA regulator N-term
FHJKHKDH_01507 8.4e-78 yhjR S Rubrerythrin
FHJKHKDH_01508 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
FHJKHKDH_01509 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
FHJKHKDH_01510 2e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
FHJKHKDH_01511 0.0 sbcC L COG0419 ATPase involved in DNA repair
FHJKHKDH_01512 3e-50 yisB V COG1403 Restriction endonuclease
FHJKHKDH_01513 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
FHJKHKDH_01514 3e-66 gerPE S Spore germination protein GerPE
FHJKHKDH_01515 6.3e-24 gerPD S Spore germination protein
FHJKHKDH_01516 5.3e-54 gerPC S Spore germination protein
FHJKHKDH_01517 4e-34 gerPB S cell differentiation
FHJKHKDH_01518 1.9e-33 gerPA S Spore germination protein
FHJKHKDH_01519 1.5e-22 yisI S Spo0E like sporulation regulatory protein
FHJKHKDH_01520 1e-173 cotH M Spore Coat
FHJKHKDH_01521 7.1e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
FHJKHKDH_01522 3e-57 yisL S UPF0344 protein
FHJKHKDH_01523 0.0 wprA O Belongs to the peptidase S8 family
FHJKHKDH_01524 3.6e-102 yisN S Protein of unknown function (DUF2777)
FHJKHKDH_01525 0.0 asnO 6.3.5.4 E Asparagine synthase
FHJKHKDH_01526 4.7e-88 yizA S Damage-inducible protein DinB
FHJKHKDH_01527 2.4e-147 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
FHJKHKDH_01528 4e-243 yisQ V Mate efflux family protein
FHJKHKDH_01529 3.5e-160 yisR K Transcriptional regulator
FHJKHKDH_01530 2.4e-184 purR K helix_turn _helix lactose operon repressor
FHJKHKDH_01531 5.2e-195 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
FHJKHKDH_01532 7e-92 yisT S DinB family
FHJKHKDH_01533 3.2e-99 argO S Lysine exporter protein LysE YggA
FHJKHKDH_01534 2.6e-269 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
FHJKHKDH_01535 4e-36 mcbG S Pentapeptide repeats (9 copies)
FHJKHKDH_01536 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
FHJKHKDH_01537 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
FHJKHKDH_01538 2.7e-232 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
FHJKHKDH_01539 2.5e-140 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
FHJKHKDH_01540 1.2e-98 comB 3.1.3.71 H Belongs to the ComB family
FHJKHKDH_01541 1.9e-141 yitD 4.4.1.19 S synthase
FHJKHKDH_01542 7.2e-113 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
FHJKHKDH_01543 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
FHJKHKDH_01544 4e-229 yitG EGP Major facilitator Superfamily
FHJKHKDH_01545 1.8e-156 yitH K Acetyltransferase (GNAT) domain
FHJKHKDH_01546 4.6e-71 yjcF S Acetyltransferase (GNAT) domain
FHJKHKDH_01547 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
FHJKHKDH_01548 8.6e-55 yajQ S Belongs to the UPF0234 family
FHJKHKDH_01549 4e-161 cvfB S protein conserved in bacteria
FHJKHKDH_01550 8.5e-94
FHJKHKDH_01551 2.8e-171
FHJKHKDH_01552 1.5e-97 S Sporulation delaying protein SdpA
FHJKHKDH_01553 4.5e-58 K Transcriptional regulator PadR-like family
FHJKHKDH_01554 2.5e-93
FHJKHKDH_01555 1.4e-44 yitR S Domain of unknown function (DUF3784)
FHJKHKDH_01556 2.7e-307 nprB 3.4.24.28 E Peptidase M4
FHJKHKDH_01557 8.4e-159 yitS S protein conserved in bacteria
FHJKHKDH_01558 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
FHJKHKDH_01559 5e-73 ipi S Intracellular proteinase inhibitor
FHJKHKDH_01560 2.8e-17 S Protein of unknown function (DUF3813)
FHJKHKDH_01562 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
FHJKHKDH_01563 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
FHJKHKDH_01564 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
FHJKHKDH_01565 1.5e-22 pilT S Proteolipid membrane potential modulator
FHJKHKDH_01566 4.3e-272 yitY C D-arabinono-1,4-lactone oxidase
FHJKHKDH_01567 1.8e-70 norB G Major Facilitator Superfamily
FHJKHKDH_01568 3.5e-199 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FHJKHKDH_01569 3.1e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FHJKHKDH_01570 2.2e-137 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
FHJKHKDH_01571 6.4e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
FHJKHKDH_01572 3.9e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
FHJKHKDH_01573 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
FHJKHKDH_01574 3.8e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FHJKHKDH_01575 9.5e-28 yjzC S YjzC-like protein
FHJKHKDH_01576 2.3e-16 yjzD S Protein of unknown function (DUF2929)
FHJKHKDH_01577 6.2e-142 yjaU I carboxylic ester hydrolase activity
FHJKHKDH_01578 7.3e-103 yjaV
FHJKHKDH_01579 1.1e-183 med S Transcriptional activator protein med
FHJKHKDH_01580 7.3e-26 comZ S ComZ
FHJKHKDH_01581 2.7e-22 yjzB
FHJKHKDH_01582 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FHJKHKDH_01583 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
FHJKHKDH_01584 7.8e-151 yjaZ O Zn-dependent protease
FHJKHKDH_01585 1.8e-184 appD P Belongs to the ABC transporter superfamily
FHJKHKDH_01586 6.5e-187 appF E Belongs to the ABC transporter superfamily
FHJKHKDH_01587 1.6e-251 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
FHJKHKDH_01588 1.2e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FHJKHKDH_01589 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FHJKHKDH_01590 5.5e-146 yjbA S Belongs to the UPF0736 family
FHJKHKDH_01591 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
FHJKHKDH_01592 0.0 oppA E ABC transporter substrate-binding protein
FHJKHKDH_01593 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FHJKHKDH_01594 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FHJKHKDH_01595 6.8e-198 oppD P Belongs to the ABC transporter superfamily
FHJKHKDH_01596 7.2e-172 oppF E Belongs to the ABC transporter superfamily
FHJKHKDH_01597 9.8e-206 yjbB EGP Major Facilitator Superfamily
FHJKHKDH_01598 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FHJKHKDH_01599 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
FHJKHKDH_01600 6e-112 yjbE P Integral membrane protein TerC family
FHJKHKDH_01601 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
FHJKHKDH_01602 7.3e-222 yjbF S Competence protein
FHJKHKDH_01603 0.0 pepF E oligoendopeptidase F
FHJKHKDH_01604 1.8e-20
FHJKHKDH_01606 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
FHJKHKDH_01607 3.7e-72 yjbI S Bacterial-like globin
FHJKHKDH_01608 3.1e-85 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
FHJKHKDH_01609 1e-99 yjbK S protein conserved in bacteria
FHJKHKDH_01610 7.1e-62 yjbL S Belongs to the UPF0738 family
FHJKHKDH_01611 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
FHJKHKDH_01612 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FHJKHKDH_01613 4e-159 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
FHJKHKDH_01614 1.6e-126 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
FHJKHKDH_01615 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
FHJKHKDH_01616 2.4e-135 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FHJKHKDH_01617 1.4e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
FHJKHKDH_01618 4.1e-214 thiO 1.4.3.19 E Glycine oxidase
FHJKHKDH_01619 2.6e-29 thiS H thiamine diphosphate biosynthetic process
FHJKHKDH_01620 4.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
FHJKHKDH_01621 2.3e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
FHJKHKDH_01622 7.6e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
FHJKHKDH_01623 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
FHJKHKDH_01624 1.4e-52 yjbX S Spore coat protein
FHJKHKDH_01625 5.2e-83 cotZ S Spore coat protein
FHJKHKDH_01626 7.6e-96 cotY S Spore coat protein Z
FHJKHKDH_01627 1.2e-67 cotX S Spore Coat Protein X and V domain
FHJKHKDH_01628 7.4e-23 cotW
FHJKHKDH_01629 3.2e-49 cotV S Spore Coat Protein X and V domain
FHJKHKDH_01630 1.9e-56 yjcA S Protein of unknown function (DUF1360)
FHJKHKDH_01633 2.9e-38 spoVIF S Stage VI sporulation protein F
FHJKHKDH_01634 0.0 yjcD 3.6.4.12 L DNA helicase
FHJKHKDH_01635 1.7e-38
FHJKHKDH_01636 6.6e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FHJKHKDH_01637 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
FHJKHKDH_01638 7e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
FHJKHKDH_01639 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
FHJKHKDH_01640 2.5e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
FHJKHKDH_01641 5.3e-98 rimJ 2.3.1.128 J Alanine acetyltransferase
FHJKHKDH_01642 1.3e-210 yjcL S Protein of unknown function (DUF819)
FHJKHKDH_01645 1.6e-38
FHJKHKDH_01646 1e-29
FHJKHKDH_01647 5e-238 M nucleic acid phosphodiester bond hydrolysis
FHJKHKDH_01649 1.4e-29 KLT Protein tyrosine kinase
FHJKHKDH_01650 4.3e-11 S YolD-like protein
FHJKHKDH_01651 1.9e-36
FHJKHKDH_01652 9e-19
FHJKHKDH_01654 4.2e-46 yjcS S Antibiotic biosynthesis monooxygenase
FHJKHKDH_01655 5.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
FHJKHKDH_01657 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
FHJKHKDH_01658 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
FHJKHKDH_01659 8.2e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
FHJKHKDH_01660 2.2e-48 yjdF S Protein of unknown function (DUF2992)
FHJKHKDH_01661 1e-90 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
FHJKHKDH_01663 5.2e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FHJKHKDH_01664 4.2e-29 S Domain of unknown function (DUF4177)
FHJKHKDH_01665 4.6e-52 yjdJ S Domain of unknown function (DUF4306)
FHJKHKDH_01666 1.6e-174 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
FHJKHKDH_01668 1.1e-264 xynD 3.5.1.104 G Polysaccharide deacetylase
FHJKHKDH_01669 5.5e-83 S Protein of unknown function (DUF2690)
FHJKHKDH_01670 3.6e-21 yjfB S Putative motility protein
FHJKHKDH_01671 5.2e-167 yjfC O Predicted Zn-dependent protease (DUF2268)
FHJKHKDH_01672 1.2e-45 T PhoQ Sensor
FHJKHKDH_01673 8.9e-104 yjgB S Domain of unknown function (DUF4309)
FHJKHKDH_01674 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
FHJKHKDH_01675 2.8e-94 yjgD S Protein of unknown function (DUF1641)
FHJKHKDH_01676 1.5e-06 S Domain of unknown function (DUF4352)
FHJKHKDH_01677 3.8e-116 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
FHJKHKDH_01679 2.4e-220 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
FHJKHKDH_01680 1.1e-217 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
FHJKHKDH_01681 8.2e-30
FHJKHKDH_01682 7.3e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
FHJKHKDH_01683 5.6e-122 ybbM S transport system, permease component
FHJKHKDH_01684 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
FHJKHKDH_01685 2.3e-176 yjlA EG Putative multidrug resistance efflux transporter
FHJKHKDH_01686 9.8e-91 yjlB S Cupin domain
FHJKHKDH_01687 7.1e-66 yjlC S Protein of unknown function (DUF1641)
FHJKHKDH_01688 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
FHJKHKDH_01689 4.3e-277 uxaC 5.3.1.12 G glucuronate isomerase
FHJKHKDH_01690 1.4e-248 yjmB G symporter YjmB
FHJKHKDH_01691 2.5e-189 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
FHJKHKDH_01692 4.8e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
FHJKHKDH_01693 3.1e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
FHJKHKDH_01694 8.9e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
FHJKHKDH_01695 4.1e-226 exuT G Sugar (and other) transporter
FHJKHKDH_01696 5.2e-184 exuR K transcriptional
FHJKHKDH_01697 1.6e-282 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
FHJKHKDH_01698 8.4e-287 uxaA 4.2.1.7, 4.4.1.24 G Altronate
FHJKHKDH_01699 4.3e-130 MA20_18170 S membrane transporter protein
FHJKHKDH_01700 2.3e-78 yjoA S DinB family
FHJKHKDH_01701 1.1e-244 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
FHJKHKDH_01702 2.3e-212 S response regulator aspartate phosphatase
FHJKHKDH_01704 6.3e-41 S YCII-related domain
FHJKHKDH_01705 8e-166 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
FHJKHKDH_01706 6.1e-61 yjqA S Bacterial PH domain
FHJKHKDH_01707 1.4e-107 yjqB S Pfam:DUF867
FHJKHKDH_01708 4.4e-160 ydbD P Catalase
FHJKHKDH_01709 1e-110 xkdA E IrrE N-terminal-like domain
FHJKHKDH_01710 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
FHJKHKDH_01712 5.9e-157 xkdB K sequence-specific DNA binding
FHJKHKDH_01713 4.1e-118 xkdC L Bacterial dnaA protein
FHJKHKDH_01716 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
FHJKHKDH_01717 2.2e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
FHJKHKDH_01718 1.2e-138 xtmA L phage terminase small subunit
FHJKHKDH_01719 1.8e-253 xtmB S phage terminase, large subunit
FHJKHKDH_01720 4.6e-285 yqbA S portal protein
FHJKHKDH_01721 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
FHJKHKDH_01722 5.8e-169 xkdG S Phage capsid family
FHJKHKDH_01723 4.3e-62 yqbG S Protein of unknown function (DUF3199)
FHJKHKDH_01724 1.1e-64 yqbH S Domain of unknown function (DUF3599)
FHJKHKDH_01725 7.6e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
FHJKHKDH_01726 1.9e-77 xkdJ
FHJKHKDH_01727 2.1e-255 xkdK S Phage tail sheath C-terminal domain
FHJKHKDH_01728 6.1e-76 xkdM S Phage tail tube protein
FHJKHKDH_01729 2.3e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
FHJKHKDH_01730 5.1e-264 xkdO L Transglycosylase SLT domain
FHJKHKDH_01731 1e-117 xkdP S Lysin motif
FHJKHKDH_01732 9e-181 yqbQ 3.2.1.96 G NLP P60 protein
FHJKHKDH_01733 1e-38 xkdR S Protein of unknown function (DUF2577)
FHJKHKDH_01734 9e-69 xkdS S Protein of unknown function (DUF2634)
FHJKHKDH_01735 3.3e-189 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
FHJKHKDH_01736 5.8e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
FHJKHKDH_01737 6.7e-41
FHJKHKDH_01738 1e-177
FHJKHKDH_01739 5.3e-45 xkdW S XkdW protein
FHJKHKDH_01740 5.5e-22 xkdX
FHJKHKDH_01741 6.4e-151 xepA
FHJKHKDH_01742 6.2e-39 xhlA S Haemolysin XhlA
FHJKHKDH_01743 9.3e-40 xhlB S SPP1 phage holin
FHJKHKDH_01744 8.6e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
FHJKHKDH_01746 6.7e-23 spoIISB S Stage II sporulation protein SB
FHJKHKDH_01747 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
FHJKHKDH_01748 5.8e-175 pit P phosphate transporter
FHJKHKDH_01749 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
FHJKHKDH_01750 2.3e-240 steT E amino acid
FHJKHKDH_01751 1.8e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
FHJKHKDH_01752 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FHJKHKDH_01753 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
FHJKHKDH_01755 2.6e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FHJKHKDH_01756 2.4e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
FHJKHKDH_01757 5.1e-153 dppA E D-aminopeptidase
FHJKHKDH_01758 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FHJKHKDH_01759 5.1e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FHJKHKDH_01760 6.6e-187 dppD P Belongs to the ABC transporter superfamily
FHJKHKDH_01761 0.0 dppE E ABC transporter substrate-binding protein
FHJKHKDH_01763 8.1e-179 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
FHJKHKDH_01764 3.2e-203 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
FHJKHKDH_01765 5.3e-172 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
FHJKHKDH_01766 7.7e-188 ykfD E Belongs to the ABC transporter superfamily
FHJKHKDH_01767 7.4e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
FHJKHKDH_01768 5.3e-161 ykgA E Amidinotransferase
FHJKHKDH_01769 1.5e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
FHJKHKDH_01770 1e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FHJKHKDH_01771 1e-07
FHJKHKDH_01772 2.7e-129 ykjA S Protein of unknown function (DUF421)
FHJKHKDH_01773 1e-98 ykkA S Protein of unknown function (DUF664)
FHJKHKDH_01774 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
FHJKHKDH_01775 3.5e-55 ykkC P Multidrug resistance protein
FHJKHKDH_01776 7e-50 ykkD P Multidrug resistance protein
FHJKHKDH_01777 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
FHJKHKDH_01778 1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FHJKHKDH_01779 2.5e-228 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FHJKHKDH_01781 1.3e-70 ohrA O Organic hydroperoxide resistance protein
FHJKHKDH_01782 4.4e-74 ohrR K COG1846 Transcriptional regulators
FHJKHKDH_01783 8.4e-72 ohrB O Organic hydroperoxide resistance protein
FHJKHKDH_01784 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
FHJKHKDH_01785 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FHJKHKDH_01786 5e-176 isp O Belongs to the peptidase S8 family
FHJKHKDH_01787 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
FHJKHKDH_01788 2e-135 ykoC P Cobalt transport protein
FHJKHKDH_01789 7.2e-308 P ABC transporter, ATP-binding protein
FHJKHKDH_01790 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
FHJKHKDH_01791 1.3e-108 ykoF S YKOF-related Family
FHJKHKDH_01792 2.7e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FHJKHKDH_01793 8.8e-243 ykoH 2.7.13.3 T Histidine kinase
FHJKHKDH_01794 3.6e-112 ykoI S Peptidase propeptide and YPEB domain
FHJKHKDH_01795 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
FHJKHKDH_01798 2.2e-222 mgtE P Acts as a magnesium transporter
FHJKHKDH_01799 1.4e-53 tnrA K transcriptional
FHJKHKDH_01800 5.9e-18
FHJKHKDH_01801 6.9e-26 ykoL
FHJKHKDH_01802 1.3e-81 mhqR K transcriptional
FHJKHKDH_01803 1.3e-215 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
FHJKHKDH_01804 1.1e-98 ykoP G polysaccharide deacetylase
FHJKHKDH_01805 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
FHJKHKDH_01806 0.0 ykoS
FHJKHKDH_01807 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
FHJKHKDH_01808 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
FHJKHKDH_01809 3.6e-160 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FHJKHKDH_01810 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
FHJKHKDH_01811 3.5e-109 ykoX S membrane-associated protein
FHJKHKDH_01812 4.6e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
FHJKHKDH_01813 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FHJKHKDH_01814 4.4e-110 rsgI S Anti-sigma factor N-terminus
FHJKHKDH_01815 1.9e-26 sspD S small acid-soluble spore protein
FHJKHKDH_01816 1.5e-124 ykrK S Domain of unknown function (DUF1836)
FHJKHKDH_01817 3.9e-154 htpX O Belongs to the peptidase M48B family
FHJKHKDH_01818 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
FHJKHKDH_01819 1.2e-10 ydfR S Protein of unknown function (DUF421)
FHJKHKDH_01820 4.1e-18 ykzE
FHJKHKDH_01821 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
FHJKHKDH_01822 0.0 kinE 2.7.13.3 T Histidine kinase
FHJKHKDH_01823 5e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FHJKHKDH_01825 1.3e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FHJKHKDH_01826 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FHJKHKDH_01827 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
FHJKHKDH_01828 9.8e-230 mtnE 2.6.1.83 E Aminotransferase
FHJKHKDH_01829 1.3e-229 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
FHJKHKDH_01830 8.3e-136 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
FHJKHKDH_01831 1.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
FHJKHKDH_01832 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FHJKHKDH_01833 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
FHJKHKDH_01834 7.5e-10 S Spo0E like sporulation regulatory protein
FHJKHKDH_01835 2.6e-63 eag
FHJKHKDH_01836 1.4e-273 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
FHJKHKDH_01837 1.3e-75 ykvE K transcriptional
FHJKHKDH_01838 2.5e-125 motB N Flagellar motor protein
FHJKHKDH_01839 2.7e-138 motA N flagellar motor
FHJKHKDH_01840 0.0 clpE O Belongs to the ClpA ClpB family
FHJKHKDH_01841 1.8e-179 ykvI S membrane
FHJKHKDH_01842 8.1e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FHJKHKDH_01843 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
FHJKHKDH_01844 3.7e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
FHJKHKDH_01845 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FHJKHKDH_01846 2e-61 ykvN K Transcriptional regulator
FHJKHKDH_01847 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
FHJKHKDH_01848 2.5e-233 ykvP 3.5.1.28 M Glycosyl transferases group 1
FHJKHKDH_01849 3.5e-35 3.5.1.104 M LysM domain
FHJKHKDH_01850 3.1e-162 G Glycosyl hydrolases family 18
FHJKHKDH_01851 1.1e-44 ykvR S Protein of unknown function (DUF3219)
FHJKHKDH_01852 6e-25 ykvS S protein conserved in bacteria
FHJKHKDH_01853 2.7e-28
FHJKHKDH_01854 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
FHJKHKDH_01855 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
FHJKHKDH_01856 2.3e-87 stoA CO thiol-disulfide
FHJKHKDH_01857 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
FHJKHKDH_01858 1.3e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
FHJKHKDH_01859 9.2e-178 ykvZ 5.1.1.1 K Transcriptional regulator
FHJKHKDH_01861 7.6e-128 glcT K antiterminator
FHJKHKDH_01862 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
FHJKHKDH_01863 2.1e-39 ptsH G phosphocarrier protein HPr
FHJKHKDH_01864 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FHJKHKDH_01865 7.2e-39 splA S Transcriptional regulator
FHJKHKDH_01866 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
FHJKHKDH_01867 1.1e-129 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FHJKHKDH_01868 8.2e-258 mcpC NT chemotaxis protein
FHJKHKDH_01869 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
FHJKHKDH_01870 5.7e-122 ykwD J protein with SCP PR1 domains
FHJKHKDH_01871 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
FHJKHKDH_01872 0.0 pilS 2.7.13.3 T Histidine kinase
FHJKHKDH_01873 6.3e-221 patA 2.6.1.1 E Aminotransferase
FHJKHKDH_01874 2.2e-15
FHJKHKDH_01875 1.4e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
FHJKHKDH_01876 1.7e-84 ykyB S YkyB-like protein
FHJKHKDH_01877 8.1e-238 ykuC EGP Major facilitator Superfamily
FHJKHKDH_01878 1.8e-87 ykuD S protein conserved in bacteria
FHJKHKDH_01879 2.3e-164 ykuE S Metallophosphoesterase
FHJKHKDH_01880 1.2e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FHJKHKDH_01881 4.4e-233 ykuI T Diguanylate phosphodiesterase
FHJKHKDH_01882 3.9e-37 ykuJ S protein conserved in bacteria
FHJKHKDH_01883 4.4e-94 ykuK S Ribonuclease H-like
FHJKHKDH_01884 3.9e-27 ykzF S Antirepressor AbbA
FHJKHKDH_01885 1.6e-76 ykuL S CBS domain
FHJKHKDH_01886 3.5e-168 ccpC K Transcriptional regulator
FHJKHKDH_01887 6.5e-84 fld C Flavodoxin domain
FHJKHKDH_01888 1.6e-176 ykuO
FHJKHKDH_01889 1.3e-78 fld C Flavodoxin
FHJKHKDH_01890 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
FHJKHKDH_01891 2.4e-214 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
FHJKHKDH_01892 9e-37 ykuS S Belongs to the UPF0180 family
FHJKHKDH_01893 8.8e-142 ykuT M Mechanosensitive ion channel
FHJKHKDH_01894 3.9e-101 ykuU O Alkyl hydroperoxide reductase
FHJKHKDH_01895 6.3e-81 ykuV CO thiol-disulfide
FHJKHKDH_01896 5.8e-95 rok K Repressor of ComK
FHJKHKDH_01897 8.4e-147 yknT
FHJKHKDH_01898 3.3e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
FHJKHKDH_01899 2.9e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
FHJKHKDH_01900 1.7e-243 moeA 2.10.1.1 H molybdopterin
FHJKHKDH_01901 1.3e-93 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
FHJKHKDH_01902 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
FHJKHKDH_01903 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FHJKHKDH_01904 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
FHJKHKDH_01905 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
FHJKHKDH_01906 8.5e-117 yknW S Yip1 domain
FHJKHKDH_01907 1.1e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FHJKHKDH_01908 2.7e-123 macB V ABC transporter, ATP-binding protein
FHJKHKDH_01909 1.1e-207 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
FHJKHKDH_01910 3.1e-136 fruR K Transcriptional regulator
FHJKHKDH_01911 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
FHJKHKDH_01912 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
FHJKHKDH_01913 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
FHJKHKDH_01914 8.1e-39 ykoA
FHJKHKDH_01915 2.2e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
FHJKHKDH_01916 4.8e-168 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FHJKHKDH_01917 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
FHJKHKDH_01918 1.1e-12 S Uncharacterized protein YkpC
FHJKHKDH_01919 7.7e-183 mreB D Rod-share determining protein MreBH
FHJKHKDH_01920 1.5e-43 abrB K of stationary sporulation gene expression
FHJKHKDH_01921 1e-240 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
FHJKHKDH_01922 2.7e-154 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
FHJKHKDH_01923 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
FHJKHKDH_01924 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FHJKHKDH_01925 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FHJKHKDH_01926 8.2e-31 ykzG S Belongs to the UPF0356 family
FHJKHKDH_01927 1.6e-146 ykrA S hydrolases of the HAD superfamily
FHJKHKDH_01928 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
FHJKHKDH_01930 2e-115 recN L Putative cell-wall binding lipoprotein
FHJKHKDH_01931 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
FHJKHKDH_01932 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
FHJKHKDH_01933 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
FHJKHKDH_01934 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
FHJKHKDH_01935 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
FHJKHKDH_01936 2.9e-276 speA 4.1.1.19 E Arginine
FHJKHKDH_01937 1.6e-42 yktA S Belongs to the UPF0223 family
FHJKHKDH_01938 6.6e-116 yktB S Belongs to the UPF0637 family
FHJKHKDH_01939 7.1e-26 ykzI
FHJKHKDH_01940 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
FHJKHKDH_01941 2e-77 ykzC S Acetyltransferase (GNAT) family
FHJKHKDH_01942 1e-170 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FHJKHKDH_01943 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
FHJKHKDH_01944 0.0 ylaA
FHJKHKDH_01945 2.7e-42 ylaB
FHJKHKDH_01946 9.6e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
FHJKHKDH_01947 2.7e-11 sigC S Putative zinc-finger
FHJKHKDH_01948 1.8e-38 ylaE
FHJKHKDH_01949 8.2e-22 S Family of unknown function (DUF5325)
FHJKHKDH_01950 0.0 typA T GTP-binding protein TypA
FHJKHKDH_01951 4.2e-47 ylaH S YlaH-like protein
FHJKHKDH_01952 2.5e-32 ylaI S protein conserved in bacteria
FHJKHKDH_01953 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
FHJKHKDH_01954 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
FHJKHKDH_01955 1e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FHJKHKDH_01956 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
FHJKHKDH_01957 2.5e-43 ylaN S Belongs to the UPF0358 family
FHJKHKDH_01958 1.2e-211 ftsW D Belongs to the SEDS family
FHJKHKDH_01959 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FHJKHKDH_01960 4.2e-164 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
FHJKHKDH_01961 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
FHJKHKDH_01962 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
FHJKHKDH_01963 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FHJKHKDH_01964 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
FHJKHKDH_01965 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
FHJKHKDH_01966 3e-167 ctaG S cytochrome c oxidase
FHJKHKDH_01967 7e-62 ylbA S YugN-like family
FHJKHKDH_01968 4.4e-74 ylbB T COG0517 FOG CBS domain
FHJKHKDH_01969 4.3e-200 ylbC S protein with SCP PR1 domains
FHJKHKDH_01970 4.1e-63 ylbD S Putative coat protein
FHJKHKDH_01971 6.7e-37 ylbE S YlbE-like protein
FHJKHKDH_01972 1.8e-75 ylbF S Belongs to the UPF0342 family
FHJKHKDH_01973 2.2e-38 ylbG S UPF0298 protein
FHJKHKDH_01974 1.6e-97 rsmD 2.1.1.171 L Methyltransferase
FHJKHKDH_01975 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FHJKHKDH_01976 1.1e-220 ylbJ S Sporulation integral membrane protein YlbJ
FHJKHKDH_01977 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
FHJKHKDH_01978 2e-186 ylbL T Belongs to the peptidase S16 family
FHJKHKDH_01979 6e-230 ylbM S Belongs to the UPF0348 family
FHJKHKDH_01981 6.6e-90 yceD S metal-binding, possibly nucleic acid-binding protein
FHJKHKDH_01982 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
FHJKHKDH_01983 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
FHJKHKDH_01984 1.5e-88 ylbP K n-acetyltransferase
FHJKHKDH_01985 1.6e-168 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FHJKHKDH_01986 1.8e-306 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
FHJKHKDH_01987 2.9e-78 mraZ K Belongs to the MraZ family
FHJKHKDH_01988 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
FHJKHKDH_01989 3.7e-44 ftsL D Essential cell division protein
FHJKHKDH_01990 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
FHJKHKDH_01991 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
FHJKHKDH_01992 8.9e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FHJKHKDH_01993 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FHJKHKDH_01994 1.7e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FHJKHKDH_01995 5.7e-186 spoVE D Belongs to the SEDS family
FHJKHKDH_01996 5.7e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FHJKHKDH_01997 5.3e-167 murB 1.3.1.98 M cell wall formation
FHJKHKDH_01998 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
FHJKHKDH_01999 4.1e-103 ylxW S protein conserved in bacteria
FHJKHKDH_02000 1.8e-91 ylxX S protein conserved in bacteria
FHJKHKDH_02001 6.2e-58 sbp S small basic protein
FHJKHKDH_02002 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
FHJKHKDH_02003 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FHJKHKDH_02004 0.0 bpr O COG1404 Subtilisin-like serine proteases
FHJKHKDH_02006 1.2e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
FHJKHKDH_02007 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FHJKHKDH_02008 6.2e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FHJKHKDH_02009 3.4e-146 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
FHJKHKDH_02010 4e-253 argE 3.5.1.16 E Acetylornithine deacetylase
FHJKHKDH_02011 2.4e-37 ylmC S sporulation protein
FHJKHKDH_02012 6.6e-156 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
FHJKHKDH_02013 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FHJKHKDH_02014 5.1e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
FHJKHKDH_02015 1.6e-39 yggT S membrane
FHJKHKDH_02016 6.7e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
FHJKHKDH_02017 2.6e-67 divIVA D Cell division initiation protein
FHJKHKDH_02018 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FHJKHKDH_02019 2.2e-63 dksA T COG1734 DnaK suppressor protein
FHJKHKDH_02020 4e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FHJKHKDH_02021 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
FHJKHKDH_02022 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FHJKHKDH_02023 7.6e-231 pyrP F Xanthine uracil
FHJKHKDH_02024 2e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
FHJKHKDH_02025 4.1e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
FHJKHKDH_02026 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
FHJKHKDH_02027 0.0 carB 6.3.5.5 F Belongs to the CarB family
FHJKHKDH_02028 1.4e-144 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
FHJKHKDH_02029 5.1e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
FHJKHKDH_02030 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
FHJKHKDH_02031 5.6e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FHJKHKDH_02033 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
FHJKHKDH_02034 5.4e-179 cysP P phosphate transporter
FHJKHKDH_02035 5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
FHJKHKDH_02036 6.2e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
FHJKHKDH_02037 4.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
FHJKHKDH_02038 4.9e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
FHJKHKDH_02039 1.1e-81 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
FHJKHKDH_02040 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
FHJKHKDH_02041 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
FHJKHKDH_02042 2.4e-156 yloC S stress-induced protein
FHJKHKDH_02043 1.5e-40 ylzA S Belongs to the UPF0296 family
FHJKHKDH_02044 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
FHJKHKDH_02045 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
FHJKHKDH_02046 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FHJKHKDH_02047 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FHJKHKDH_02048 1.3e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
FHJKHKDH_02049 1.1e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FHJKHKDH_02050 8.4e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FHJKHKDH_02051 1.4e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
FHJKHKDH_02052 1.6e-140 stp 3.1.3.16 T phosphatase
FHJKHKDH_02053 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
FHJKHKDH_02054 3.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
FHJKHKDH_02055 8e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
FHJKHKDH_02056 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
FHJKHKDH_02057 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
FHJKHKDH_02058 5.5e-59 asp S protein conserved in bacteria
FHJKHKDH_02059 4.3e-300 yloV S kinase related to dihydroxyacetone kinase
FHJKHKDH_02060 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
FHJKHKDH_02061 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
FHJKHKDH_02062 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FHJKHKDH_02063 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
FHJKHKDH_02064 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
FHJKHKDH_02065 2.9e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
FHJKHKDH_02066 6.1e-129 IQ reductase
FHJKHKDH_02067 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
FHJKHKDH_02068 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
FHJKHKDH_02069 0.0 smc D Required for chromosome condensation and partitioning
FHJKHKDH_02070 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FHJKHKDH_02071 2.9e-87
FHJKHKDH_02072 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FHJKHKDH_02073 6e-236 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FHJKHKDH_02074 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
FHJKHKDH_02075 4.5e-36 ylqC S Belongs to the UPF0109 family
FHJKHKDH_02076 6.3e-61 ylqD S YlqD protein
FHJKHKDH_02077 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FHJKHKDH_02078 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
FHJKHKDH_02079 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
FHJKHKDH_02080 1.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FHJKHKDH_02081 6.9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FHJKHKDH_02082 1e-288 ylqG
FHJKHKDH_02083 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
FHJKHKDH_02084 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
FHJKHKDH_02085 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FHJKHKDH_02086 5e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
FHJKHKDH_02087 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FHJKHKDH_02088 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FHJKHKDH_02089 2.5e-169 xerC L tyrosine recombinase XerC
FHJKHKDH_02090 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FHJKHKDH_02091 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FHJKHKDH_02092 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FHJKHKDH_02093 6.8e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
FHJKHKDH_02094 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
FHJKHKDH_02095 1.9e-31 fliE N Flagellar hook-basal body
FHJKHKDH_02096 2.4e-255 fliF N The M ring may be actively involved in energy transduction
FHJKHKDH_02097 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
FHJKHKDH_02098 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
FHJKHKDH_02099 7.2e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
FHJKHKDH_02100 1.5e-69 fliJ N Flagellar biosynthesis chaperone
FHJKHKDH_02101 7.7e-37 ylxF S MgtE intracellular N domain
FHJKHKDH_02102 4.4e-216 fliK N Flagellar hook-length control protein
FHJKHKDH_02103 1.7e-72 flgD N Flagellar basal body rod modification protein
FHJKHKDH_02104 8.2e-140 flgG N Flagellar basal body rod
FHJKHKDH_02105 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
FHJKHKDH_02106 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
FHJKHKDH_02107 5.9e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FHJKHKDH_02108 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
FHJKHKDH_02109 2.1e-96 fliZ N Flagellar biosynthesis protein, FliO
FHJKHKDH_02110 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
FHJKHKDH_02111 2.2e-36 fliQ N Role in flagellar biosynthesis
FHJKHKDH_02112 3.6e-132 fliR N Flagellar biosynthetic protein FliR
FHJKHKDH_02113 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FHJKHKDH_02114 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FHJKHKDH_02115 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
FHJKHKDH_02116 7.5e-158 flhG D Belongs to the ParA family
FHJKHKDH_02117 7.5e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
FHJKHKDH_02118 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
FHJKHKDH_02119 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
FHJKHKDH_02120 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
FHJKHKDH_02121 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
FHJKHKDH_02122 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FHJKHKDH_02123 3.1e-76 ylxL
FHJKHKDH_02124 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
FHJKHKDH_02125 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FHJKHKDH_02126 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
FHJKHKDH_02127 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
FHJKHKDH_02128 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FHJKHKDH_02129 7.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
FHJKHKDH_02130 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
FHJKHKDH_02131 7.7e-233 rasP M zinc metalloprotease
FHJKHKDH_02132 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
FHJKHKDH_02133 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FHJKHKDH_02134 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
FHJKHKDH_02135 1.1e-203 nusA K Participates in both transcription termination and antitermination
FHJKHKDH_02136 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
FHJKHKDH_02137 3.1e-47 ylxQ J ribosomal protein
FHJKHKDH_02138 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FHJKHKDH_02139 3e-44 ylxP S protein conserved in bacteria
FHJKHKDH_02140 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FHJKHKDH_02141 1.8e-170 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FHJKHKDH_02142 6.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
FHJKHKDH_02143 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FHJKHKDH_02144 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
FHJKHKDH_02145 8.3e-179 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
FHJKHKDH_02146 4.4e-233 pepR S Belongs to the peptidase M16 family
FHJKHKDH_02147 2.6e-42 ymxH S YlmC YmxH family
FHJKHKDH_02148 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
FHJKHKDH_02149 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
FHJKHKDH_02150 3.2e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FHJKHKDH_02151 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
FHJKHKDH_02152 4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FHJKHKDH_02153 7.3e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FHJKHKDH_02154 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
FHJKHKDH_02155 4.4e-32 S YlzJ-like protein
FHJKHKDH_02156 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
FHJKHKDH_02157 1.4e-133 ymfC K Transcriptional regulator
FHJKHKDH_02158 3.8e-205 ymfD EGP Major facilitator Superfamily
FHJKHKDH_02159 2e-233 ymfF S Peptidase M16
FHJKHKDH_02160 4.1e-242 ymfH S zinc protease
FHJKHKDH_02161 7.8e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
FHJKHKDH_02162 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
FHJKHKDH_02163 2.7e-143 ymfK S Protein of unknown function (DUF3388)
FHJKHKDH_02164 1.9e-124 ymfM S protein conserved in bacteria
FHJKHKDH_02165 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FHJKHKDH_02166 9.6e-236 cinA 3.5.1.42 S Belongs to the CinA family
FHJKHKDH_02167 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FHJKHKDH_02168 2.6e-214 pbpX V Beta-lactamase
FHJKHKDH_02169 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
FHJKHKDH_02170 7.1e-152 ymdB S protein conserved in bacteria
FHJKHKDH_02171 1.2e-36 spoVS S Stage V sporulation protein S
FHJKHKDH_02172 3e-198 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
FHJKHKDH_02173 7.2e-217 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
FHJKHKDH_02174 8.5e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FHJKHKDH_02175 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
FHJKHKDH_02176 2.2e-88 cotE S Spore coat protein
FHJKHKDH_02177 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FHJKHKDH_02178 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FHJKHKDH_02179 5.1e-70 S Regulatory protein YrvL
FHJKHKDH_02181 7.9e-97 ymcC S Membrane
FHJKHKDH_02182 2.9e-108 pksA K Transcriptional regulator
FHJKHKDH_02183 3.7e-125 pksB 3.1.2.6 S Polyketide biosynthesis
FHJKHKDH_02184 1.1e-161 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
FHJKHKDH_02186 2.3e-184 pksD Q Acyl transferase domain
FHJKHKDH_02187 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
FHJKHKDH_02188 1.4e-37 acpK IQ Phosphopantetheine attachment site
FHJKHKDH_02189 1.3e-237 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
FHJKHKDH_02190 1.3e-245 pksG 2.3.3.10 I synthase
FHJKHKDH_02191 1.3e-142 pksH 4.2.1.18 I enoyl-CoA hydratase
FHJKHKDH_02192 1.7e-134 pksI I Belongs to the enoyl-CoA hydratase isomerase family
FHJKHKDH_02193 0.0 rhiB IQ polyketide synthase
FHJKHKDH_02194 0.0 pfaA Q Polyketide synthase of type I
FHJKHKDH_02195 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
FHJKHKDH_02196 0.0 dhbF IQ polyketide synthase
FHJKHKDH_02197 0.0 pks13 HQ Beta-ketoacyl synthase
FHJKHKDH_02198 1.4e-231 cypA C Cytochrome P450
FHJKHKDH_02199 1.7e-60 ymzB
FHJKHKDH_02200 1.8e-161 ymaE S Metallo-beta-lactamase superfamily
FHJKHKDH_02201 9.5e-250 aprX O Belongs to the peptidase S8 family
FHJKHKDH_02202 1.9e-07 K Transcriptional regulator
FHJKHKDH_02203 2.1e-126 ymaC S Replication protein
FHJKHKDH_02204 2.1e-79 ymaD O redox protein, regulator of disulfide bond formation
FHJKHKDH_02205 1.4e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
FHJKHKDH_02206 5.4e-50 ebrA P Small Multidrug Resistance protein
FHJKHKDH_02208 2.1e-46 ymaF S YmaF family
FHJKHKDH_02209 3.5e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FHJKHKDH_02210 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
FHJKHKDH_02211 8.2e-23
FHJKHKDH_02212 4.5e-22 ymzA
FHJKHKDH_02213 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
FHJKHKDH_02214 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FHJKHKDH_02215 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FHJKHKDH_02216 2e-109 ymaB
FHJKHKDH_02217 5.2e-115 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
FHJKHKDH_02218 1.7e-176 spoVK O stage V sporulation protein K
FHJKHKDH_02219 1.8e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FHJKHKDH_02220 4.8e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
FHJKHKDH_02221 1.1e-68 glnR K transcriptional
FHJKHKDH_02222 3.5e-260 glnA 6.3.1.2 E glutamine synthetase
FHJKHKDH_02223 2.3e-38 L Arm DNA-binding domain
FHJKHKDH_02224 2.9e-102 dnaB 3.6.4.12 L replicative DNA helicase
FHJKHKDH_02225 1.6e-21
FHJKHKDH_02228 1.5e-50 wecC 1.1.1.336 M ArpU family transcriptional regulator
FHJKHKDH_02229 2.7e-26 S FRG
FHJKHKDH_02230 5.4e-66 S regulation of transcription, DNA-dependent
FHJKHKDH_02231 3.1e-18 N HicA toxin of bacterial toxin-antitoxin,
FHJKHKDH_02236 4.4e-48 V HNH endonuclease
FHJKHKDH_02237 1.8e-79 L phage terminase small subunit
FHJKHKDH_02238 4.7e-35 S Terminase
FHJKHKDH_02241 5e-10
FHJKHKDH_02242 1e-31
FHJKHKDH_02243 2.7e-70 Q Collagen triple helix repeat (20 copies)
FHJKHKDH_02244 3.8e-51 mdxE G COG2182 Maltose-binding periplasmic proteins domains
FHJKHKDH_02245 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
FHJKHKDH_02246 8.8e-173 yvdE K Transcriptional regulator
FHJKHKDH_02247 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
FHJKHKDH_02248 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
FHJKHKDH_02249 6.2e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
FHJKHKDH_02250 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
FHJKHKDH_02251 5.1e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FHJKHKDH_02252 0.0 yxdM V ABC transporter (permease)
FHJKHKDH_02253 5.6e-141 yvcR V ABC transporter, ATP-binding protein
FHJKHKDH_02254 4.1e-195 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
FHJKHKDH_02255 4.3e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FHJKHKDH_02256 1.8e-33
FHJKHKDH_02257 4e-144 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
FHJKHKDH_02258 1.6e-36 crh G Phosphocarrier protein Chr
FHJKHKDH_02259 1.4e-170 whiA K May be required for sporulation
FHJKHKDH_02260 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
FHJKHKDH_02261 5.7e-166 rapZ S Displays ATPase and GTPase activities
FHJKHKDH_02262 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
FHJKHKDH_02263 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
FHJKHKDH_02264 1.8e-97 usp CBM50 M protein conserved in bacteria
FHJKHKDH_02265 2.9e-276 S COG0457 FOG TPR repeat
FHJKHKDH_02266 0.0 msbA2 3.6.3.44 V ABC transporter
FHJKHKDH_02268 0.0
FHJKHKDH_02269 4.6e-121
FHJKHKDH_02270 8e-114 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
FHJKHKDH_02271 1.4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
FHJKHKDH_02272 8.4e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FHJKHKDH_02273 6.2e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FHJKHKDH_02274 4.7e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
FHJKHKDH_02275 2.2e-227 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FHJKHKDH_02276 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
FHJKHKDH_02277 2.4e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FHJKHKDH_02278 3.8e-139 yvpB NU protein conserved in bacteria
FHJKHKDH_02279 5.1e-119 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
FHJKHKDH_02280 1.6e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
FHJKHKDH_02281 3.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
FHJKHKDH_02282 1.6e-163 yvoD P COG0370 Fe2 transport system protein B
FHJKHKDH_02283 2.4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FHJKHKDH_02284 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FHJKHKDH_02285 2.5e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
FHJKHKDH_02286 2.7e-129 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
FHJKHKDH_02287 3.6e-134 yvoA K transcriptional
FHJKHKDH_02288 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
FHJKHKDH_02289 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
FHJKHKDH_02290 4.1e-231 cypX 1.14.15.13 C Cytochrome P450
FHJKHKDH_02291 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
FHJKHKDH_02292 2e-86 yvmB K helix_turn_helix multiple antibiotic resistance protein
FHJKHKDH_02293 2.7e-203 yvmA EGP Major facilitator Superfamily
FHJKHKDH_02294 1.2e-50 yvlD S Membrane
FHJKHKDH_02295 1.7e-25 pspB KT PspC domain
FHJKHKDH_02296 1e-164 yvlB S Putative adhesin
FHJKHKDH_02297 1.8e-48 yvlA
FHJKHKDH_02298 5.7e-33 yvkN
FHJKHKDH_02299 1.2e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FHJKHKDH_02300 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
FHJKHKDH_02301 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
FHJKHKDH_02302 1.2e-30 csbA S protein conserved in bacteria
FHJKHKDH_02303 0.0 yvkC 2.7.9.2 GT Phosphotransferase
FHJKHKDH_02304 7.8e-100 yvkB K Transcriptional regulator
FHJKHKDH_02305 3.3e-226 yvkA EGP Major facilitator Superfamily
FHJKHKDH_02306 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FHJKHKDH_02307 5.3e-56 swrA S Swarming motility protein
FHJKHKDH_02308 1.5e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
FHJKHKDH_02309 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
FHJKHKDH_02310 2.7e-123 ftsE D cell division ATP-binding protein FtsE
FHJKHKDH_02311 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
FHJKHKDH_02312 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
FHJKHKDH_02313 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FHJKHKDH_02314 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
FHJKHKDH_02315 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FHJKHKDH_02316 2.8e-66
FHJKHKDH_02317 1.9e-08 fliT S bacterial-type flagellum organization
FHJKHKDH_02318 2.5e-68 fliS N flagellar protein FliS
FHJKHKDH_02319 2.2e-247 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FHJKHKDH_02320 7.8e-52 flaG N flagellar protein FlaG
FHJKHKDH_02321 5.9e-93 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FHJKHKDH_02322 6.3e-29 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FHJKHKDH_02323 8e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FHJKHKDH_02324 1.3e-49 yviE
FHJKHKDH_02325 7.8e-155 flgL N Belongs to the bacterial flagellin family
FHJKHKDH_02326 1.2e-264 flgK N flagellar hook-associated protein
FHJKHKDH_02327 4.1e-78 flgN NOU FlgN protein
FHJKHKDH_02328 1.6e-39 flgM KNU Negative regulator of flagellin synthesis
FHJKHKDH_02329 7e-74 yvyF S flagellar protein
FHJKHKDH_02330 2.3e-125 comFC S Phosphoribosyl transferase domain
FHJKHKDH_02331 3.7e-45 comFB S Late competence development protein ComFB
FHJKHKDH_02332 4e-267 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FHJKHKDH_02333 2.1e-154 degV S protein conserved in bacteria
FHJKHKDH_02334 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FHJKHKDH_02335 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
FHJKHKDH_02336 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
FHJKHKDH_02337 6e-163 yvhJ K Transcriptional regulator
FHJKHKDH_02338 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
FHJKHKDH_02339 3.2e-236 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
FHJKHKDH_02340 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
FHJKHKDH_02341 1.5e-113 tuaF M protein involved in exopolysaccharide biosynthesis
FHJKHKDH_02342 1.8e-262 tuaE M Teichuronic acid biosynthesis protein
FHJKHKDH_02343 2e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FHJKHKDH_02344 7.6e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
FHJKHKDH_02345 4.4e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
FHJKHKDH_02346 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
FHJKHKDH_02347 2.8e-93 M Glycosyltransferase like family 2
FHJKHKDH_02348 9.1e-209 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
FHJKHKDH_02349 0.0 lytB 3.5.1.28 D Stage II sporulation protein
FHJKHKDH_02350 1e-11
FHJKHKDH_02351 2.7e-158 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
FHJKHKDH_02352 4.1e-217 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
FHJKHKDH_02353 4.6e-88 M Glycosyltransferase like family 2
FHJKHKDH_02354 8.4e-101 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
FHJKHKDH_02355 1.8e-22 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
FHJKHKDH_02356 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
FHJKHKDH_02357 1.9e-268 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
FHJKHKDH_02358 8.5e-132 tagG GM Transport permease protein
FHJKHKDH_02359 1.3e-88
FHJKHKDH_02360 2.7e-55
FHJKHKDH_02361 1.3e-208 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
FHJKHKDH_02362 6.5e-89 ggaA M Glycosyltransferase like family 2
FHJKHKDH_02363 1.5e-145 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FHJKHKDH_02364 2.1e-56 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
FHJKHKDH_02365 7.1e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
FHJKHKDH_02366 1.9e-105 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FHJKHKDH_02367 2.6e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
FHJKHKDH_02368 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
FHJKHKDH_02369 2.5e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
FHJKHKDH_02370 2e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
FHJKHKDH_02371 1.5e-214 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
FHJKHKDH_02372 2.5e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
FHJKHKDH_02373 3.8e-244 gerBA EG Spore germination protein
FHJKHKDH_02374 4.7e-186 gerBB E Spore germination protein
FHJKHKDH_02375 1.2e-197 gerAC S Spore germination protein
FHJKHKDH_02376 4.1e-248 ywtG EGP Major facilitator Superfamily
FHJKHKDH_02377 2.3e-168 ywtF K Transcriptional regulator
FHJKHKDH_02378 4.2e-158 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
FHJKHKDH_02379 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
FHJKHKDH_02380 3.6e-21 ywtC
FHJKHKDH_02381 6.3e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
FHJKHKDH_02382 8.6e-70 pgsC S biosynthesis protein
FHJKHKDH_02383 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
FHJKHKDH_02384 9.3e-178 rbsR K transcriptional
FHJKHKDH_02385 6.5e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FHJKHKDH_02386 1.4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
FHJKHKDH_02387 2.5e-275 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
FHJKHKDH_02388 9.3e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
FHJKHKDH_02389 2.4e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
FHJKHKDH_02390 9e-90 batE T Sh3 type 3 domain protein
FHJKHKDH_02391 8e-48 ywsA S Protein of unknown function (DUF3892)
FHJKHKDH_02392 4.4e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
FHJKHKDH_02393 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
FHJKHKDH_02394 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
FHJKHKDH_02395 1.1e-169 alsR K LysR substrate binding domain
FHJKHKDH_02396 1.9e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FHJKHKDH_02397 3.1e-124 ywrJ
FHJKHKDH_02398 7.6e-131 cotB
FHJKHKDH_02399 1.3e-209 cotH M Spore Coat
FHJKHKDH_02400 3.7e-12
FHJKHKDH_02401 2.4e-110 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FHJKHKDH_02402 5e-54 S Domain of unknown function (DUF4181)
FHJKHKDH_02403 1.4e-303 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
FHJKHKDH_02404 8e-82 ywrC K Transcriptional regulator
FHJKHKDH_02405 1.6e-103 ywrB P Chromate transporter
FHJKHKDH_02406 6.4e-88 ywrA P COG2059 Chromate transport protein ChrA
FHJKHKDH_02408 3.3e-100 ywqN S NAD(P)H-dependent
FHJKHKDH_02409 4.9e-162 K Transcriptional regulator
FHJKHKDH_02410 3.1e-122 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
FHJKHKDH_02411 1.7e-98
FHJKHKDH_02413 7.4e-51
FHJKHKDH_02414 1.1e-75
FHJKHKDH_02415 8.2e-239 ywqJ S Pre-toxin TG
FHJKHKDH_02416 2e-37 ywqI S Family of unknown function (DUF5344)
FHJKHKDH_02417 1e-19 S Domain of unknown function (DUF5082)
FHJKHKDH_02418 5.4e-152 ywqG S Domain of unknown function (DUF1963)
FHJKHKDH_02419 3.4e-247 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FHJKHKDH_02420 7.4e-138 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
FHJKHKDH_02421 2.2e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
FHJKHKDH_02422 2e-116 ywqC M biosynthesis protein
FHJKHKDH_02423 1.2e-17
FHJKHKDH_02424 1.2e-307 ywqB S SWIM zinc finger
FHJKHKDH_02425 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
FHJKHKDH_02426 1.3e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
FHJKHKDH_02427 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
FHJKHKDH_02428 9.8e-58 ssbB L Single-stranded DNA-binding protein
FHJKHKDH_02429 1.9e-65 ywpG
FHJKHKDH_02430 6.9e-66 ywpF S YwpF-like protein
FHJKHKDH_02431 2.6e-49 srtA 3.4.22.70 M Sortase family
FHJKHKDH_02432 1e-39 ywpD T PhoQ Sensor
FHJKHKDH_02433 1.4e-51 ywpD T Histidine kinase
FHJKHKDH_02434 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
FHJKHKDH_02435 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
FHJKHKDH_02436 2.6e-197 S aspartate phosphatase
FHJKHKDH_02437 2.6e-141 flhP N flagellar basal body
FHJKHKDH_02438 1.4e-123 flhO N flagellar basal body
FHJKHKDH_02439 3.5e-180 mbl D Rod shape-determining protein
FHJKHKDH_02440 3e-44 spoIIID K Stage III sporulation protein D
FHJKHKDH_02441 2.1e-70 ywoH K COG1846 Transcriptional regulators
FHJKHKDH_02442 2.7e-211 ywoG EGP Major facilitator Superfamily
FHJKHKDH_02443 6.2e-215 ywoF P Right handed beta helix region
FHJKHKDH_02444 1.4e-278 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
FHJKHKDH_02445 1.1e-240 ywoD EGP Major facilitator superfamily
FHJKHKDH_02446 6.8e-104 phzA Q Isochorismatase family
FHJKHKDH_02447 1.3e-76
FHJKHKDH_02448 4.3e-225 amt P Ammonium transporter
FHJKHKDH_02449 1.6e-58 nrgB K Belongs to the P(II) protein family
FHJKHKDH_02450 1.3e-102 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
FHJKHKDH_02451 7.8e-73 ywnJ S VanZ like family
FHJKHKDH_02452 2e-115 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
FHJKHKDH_02453 4.1e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
FHJKHKDH_02454 7.2e-09 ywnC S Family of unknown function (DUF5362)
FHJKHKDH_02455 2.9e-70 ywnF S Family of unknown function (DUF5392)
FHJKHKDH_02456 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FHJKHKDH_02457 1e-142 mta K transcriptional
FHJKHKDH_02458 1.7e-58 ywnC S Family of unknown function (DUF5362)
FHJKHKDH_02459 5.3e-113 ywnB S NAD(P)H-binding
FHJKHKDH_02460 1.7e-64 ywnA K Transcriptional regulator
FHJKHKDH_02461 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
FHJKHKDH_02462 1.9e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
FHJKHKDH_02463 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
FHJKHKDH_02464 7.8e-11 urtE E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
FHJKHKDH_02465 3.2e-10 csbD K CsbD-like
FHJKHKDH_02466 3e-84 ywmF S Peptidase M50
FHJKHKDH_02467 1.3e-103 S response regulator aspartate phosphatase
FHJKHKDH_02468 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FHJKHKDH_02469 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FHJKHKDH_02471 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
FHJKHKDH_02472 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
FHJKHKDH_02473 3.5e-175 spoIID D Stage II sporulation protein D
FHJKHKDH_02474 3.6e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FHJKHKDH_02475 3.4e-132 ywmB S TATA-box binding
FHJKHKDH_02476 1.3e-32 ywzB S membrane
FHJKHKDH_02477 9e-86 ywmA
FHJKHKDH_02478 2.5e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
FHJKHKDH_02479 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FHJKHKDH_02480 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FHJKHKDH_02481 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FHJKHKDH_02482 1.6e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FHJKHKDH_02483 3.9e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FHJKHKDH_02484 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FHJKHKDH_02485 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
FHJKHKDH_02486 2.5e-62 atpI S ATP synthase
FHJKHKDH_02487 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FHJKHKDH_02488 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FHJKHKDH_02489 3.6e-94 ywlG S Belongs to the UPF0340 family
FHJKHKDH_02490 8.3e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
FHJKHKDH_02491 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FHJKHKDH_02492 1.7e-91 mntP P Probably functions as a manganese efflux pump
FHJKHKDH_02493 5.2e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
FHJKHKDH_02494 4.7e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
FHJKHKDH_02495 2.6e-110 spoIIR S stage II sporulation protein R
FHJKHKDH_02496 3.7e-55 ywlA S Uncharacterised protein family (UPF0715)
FHJKHKDH_02498 2.3e-156 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
FHJKHKDH_02499 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FHJKHKDH_02500 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
FHJKHKDH_02501 7.1e-90 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
FHJKHKDH_02502 8.6e-160 ywkB S Membrane transport protein
FHJKHKDH_02503 0.0 sfcA 1.1.1.38 C malic enzyme
FHJKHKDH_02504 7e-104 tdk 2.7.1.21 F thymidine kinase
FHJKHKDH_02505 1.1e-32 rpmE J Binds the 23S rRNA
FHJKHKDH_02506 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FHJKHKDH_02507 9.5e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
FHJKHKDH_02508 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FHJKHKDH_02509 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FHJKHKDH_02510 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
FHJKHKDH_02511 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
FHJKHKDH_02512 1.2e-91 ywjG S Domain of unknown function (DUF2529)
FHJKHKDH_02513 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
FHJKHKDH_02514 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
FHJKHKDH_02515 2.4e-209 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
FHJKHKDH_02516 0.0 fadF C COG0247 Fe-S oxidoreductase
FHJKHKDH_02517 2.9e-221 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
FHJKHKDH_02518 3.3e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
FHJKHKDH_02519 2.7e-42 ywjC
FHJKHKDH_02520 3.4e-94 ywjB H RibD C-terminal domain
FHJKHKDH_02521 0.0 ywjA V ABC transporter
FHJKHKDH_02522 3.2e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FHJKHKDH_02523 1.8e-124 narI 1.7.5.1 C nitrate reductase, gamma
FHJKHKDH_02524 6.8e-93 narJ 1.7.5.1 C nitrate reductase
FHJKHKDH_02525 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
FHJKHKDH_02526 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FHJKHKDH_02527 2e-85 arfM T cyclic nucleotide binding
FHJKHKDH_02528 1.1e-138 ywiC S YwiC-like protein
FHJKHKDH_02529 2e-129 fnr K helix_turn_helix, cAMP Regulatory protein
FHJKHKDH_02530 1.1e-212 narK P COG2223 Nitrate nitrite transporter
FHJKHKDH_02531 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
FHJKHKDH_02532 4.7e-73 ywiB S protein conserved in bacteria
FHJKHKDH_02533 1e-07 S Bacteriocin subtilosin A
FHJKHKDH_02534 2.6e-271 C Fe-S oxidoreductases
FHJKHKDH_02536 3.3e-132 cbiO V ABC transporter
FHJKHKDH_02537 1e-235 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
FHJKHKDH_02538 2.1e-216 2.7.1.26, 2.7.7.2 L Peptidase, M16
FHJKHKDH_02539 1.2e-249 L Peptidase, M16
FHJKHKDH_02541 9.2e-248 ywhL CO amine dehydrogenase activity
FHJKHKDH_02542 2.7e-191 ywhK CO amine dehydrogenase activity
FHJKHKDH_02543 2.6e-78 S aspartate phosphatase
FHJKHKDH_02547 1.7e-20
FHJKHKDH_02550 1.4e-57 V ATPases associated with a variety of cellular activities
FHJKHKDH_02552 1.3e-167 speB 3.5.3.11 E Belongs to the arginase family
FHJKHKDH_02553 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FHJKHKDH_02554 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
FHJKHKDH_02555 8.9e-95 ywhD S YwhD family
FHJKHKDH_02556 5.1e-119 ywhC S Peptidase family M50
FHJKHKDH_02557 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
FHJKHKDH_02558 9.5e-71 ywhA K Transcriptional regulator
FHJKHKDH_02559 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FHJKHKDH_02561 1.1e-207 mmr U Major Facilitator Superfamily
FHJKHKDH_02562 9.8e-16 mmr U Major Facilitator Superfamily
FHJKHKDH_02563 1.4e-78 yffB K Transcriptional regulator
FHJKHKDH_02564 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
FHJKHKDH_02565 1.9e-255 ywfO S COG1078 HD superfamily phosphohydrolases
FHJKHKDH_02566 3.1e-36 ywzC S Belongs to the UPF0741 family
FHJKHKDH_02567 5.1e-110 rsfA_1
FHJKHKDH_02568 9.2e-156 ywfM EG EamA-like transporter family
FHJKHKDH_02569 5.6e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
FHJKHKDH_02570 1.1e-156 cysL K Transcriptional regulator
FHJKHKDH_02571 1.6e-174 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
FHJKHKDH_02572 1.1e-146 ywfI C May function as heme-dependent peroxidase
FHJKHKDH_02573 2.2e-137 IQ Enoyl-(Acyl carrier protein) reductase
FHJKHKDH_02574 1.6e-232 ywfG 2.6.1.83 E Aminotransferase class I and II
FHJKHKDH_02575 7.3e-209 bacE EGP Major facilitator Superfamily
FHJKHKDH_02576 4e-270 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
FHJKHKDH_02577 1.1e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FHJKHKDH_02578 4.9e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
FHJKHKDH_02579 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
FHJKHKDH_02580 2.3e-205 ywfA EGP Major facilitator Superfamily
FHJKHKDH_02581 4e-262 lysP E amino acid
FHJKHKDH_02582 0.0 rocB E arginine degradation protein
FHJKHKDH_02583 1.4e-297 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
FHJKHKDH_02584 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
FHJKHKDH_02585 1.8e-78
FHJKHKDH_02586 3.5e-87 spsL 5.1.3.13 M Spore Coat
FHJKHKDH_02587 5.3e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
FHJKHKDH_02588 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
FHJKHKDH_02589 1.9e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FHJKHKDH_02590 1.7e-190 spsG M Spore Coat
FHJKHKDH_02591 9.7e-132 spsF M Spore Coat
FHJKHKDH_02592 3.5e-213 spsE 2.5.1.56 M acid synthase
FHJKHKDH_02593 1.2e-163 spsD 2.3.1.210 K Spore Coat
FHJKHKDH_02594 3.5e-224 spsC E Belongs to the DegT DnrJ EryC1 family
FHJKHKDH_02595 7.5e-266 spsB M Capsule polysaccharide biosynthesis protein
FHJKHKDH_02596 3.1e-144 spsA M Spore Coat
FHJKHKDH_02597 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
FHJKHKDH_02598 4.3e-59 ywdK S small membrane protein
FHJKHKDH_02599 3.7e-238 ywdJ F Xanthine uracil
FHJKHKDH_02600 5e-48 ywdI S Family of unknown function (DUF5327)
FHJKHKDH_02601 1.5e-261 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
FHJKHKDH_02602 1.1e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FHJKHKDH_02603 1.2e-151 ywdF GT2,GT4 S Glycosyltransferase like family 2
FHJKHKDH_02605 1.4e-113 ywdD
FHJKHKDH_02606 1.3e-57 pex K Transcriptional regulator PadR-like family
FHJKHKDH_02607 3.9e-145 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
FHJKHKDH_02608 2e-28 ywdA
FHJKHKDH_02609 2e-290 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
FHJKHKDH_02610 8.1e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
FHJKHKDH_02611 5.7e-138 focA P Formate/nitrite transporter
FHJKHKDH_02612 7e-150 sacT K transcriptional antiterminator
FHJKHKDH_02614 0.0 vpr O Belongs to the peptidase S8 family
FHJKHKDH_02615 3.3e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FHJKHKDH_02616 1e-136 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
FHJKHKDH_02617 8.6e-202 rodA D Belongs to the SEDS family
FHJKHKDH_02618 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
FHJKHKDH_02619 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
FHJKHKDH_02620 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
FHJKHKDH_02621 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FHJKHKDH_02622 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
FHJKHKDH_02623 1e-35 ywzA S membrane
FHJKHKDH_02624 1.5e-302 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
FHJKHKDH_02625 3.8e-226 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FHJKHKDH_02626 9.5e-60 gtcA S GtrA-like protein
FHJKHKDH_02627 2.2e-122 ywcC K transcriptional regulator
FHJKHKDH_02629 9.8e-49 ywcB S Protein of unknown function, DUF485
FHJKHKDH_02630 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FHJKHKDH_02631 9.3e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
FHJKHKDH_02632 3.2e-223 ywbN P Dyp-type peroxidase family protein
FHJKHKDH_02633 1.6e-184 ycdO P periplasmic lipoprotein involved in iron transport
FHJKHKDH_02634 6.5e-252 P COG0672 High-affinity Fe2 Pb2 permease
FHJKHKDH_02635 7.2e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
FHJKHKDH_02636 8.2e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FHJKHKDH_02637 4.3e-153 ywbI K Transcriptional regulator
FHJKHKDH_02638 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
FHJKHKDH_02639 2.3e-111 ywbG M effector of murein hydrolase
FHJKHKDH_02640 1.2e-206 ywbF EGP Major facilitator Superfamily
FHJKHKDH_02641 2.3e-27 ywbE S Uncharacterized conserved protein (DUF2196)
FHJKHKDH_02642 4.1e-220 ywbD 2.1.1.191 J Methyltransferase
FHJKHKDH_02643 4.4e-67 ywbC 4.4.1.5 E glyoxalase
FHJKHKDH_02644 6.4e-246 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
FHJKHKDH_02645 9.9e-272 epr 3.4.21.62 O Belongs to the peptidase S8 family
FHJKHKDH_02646 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
FHJKHKDH_02647 1.2e-152 sacY K transcriptional antiterminator
FHJKHKDH_02648 2.9e-167 gspA M General stress
FHJKHKDH_02649 8.2e-123 ywaF S Integral membrane protein
FHJKHKDH_02650 2e-86 ywaE K Transcriptional regulator
FHJKHKDH_02651 1.3e-232 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FHJKHKDH_02652 1.5e-250 ywaD 3.4.11.10, 3.4.11.6 S PA domain
FHJKHKDH_02653 2.4e-92 K Helix-turn-helix XRE-family like proteins
FHJKHKDH_02654 3.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
FHJKHKDH_02655 1e-130 ynfM EGP Major facilitator Superfamily
FHJKHKDH_02656 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
FHJKHKDH_02657 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
FHJKHKDH_02658 6.7e-292 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FHJKHKDH_02659 1.2e-232 dltB M membrane protein involved in D-alanine export
FHJKHKDH_02660 9.6e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FHJKHKDH_02661 8.8e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FHJKHKDH_02662 1.1e-136 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
FHJKHKDH_02663 5.3e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
FHJKHKDH_02664 2.4e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
FHJKHKDH_02665 1.5e-50 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
FHJKHKDH_02666 2.4e-248 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
FHJKHKDH_02667 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
FHJKHKDH_02668 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
FHJKHKDH_02669 1.1e-19 yxzF
FHJKHKDH_02670 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
FHJKHKDH_02671 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
FHJKHKDH_02672 2.1e-211 yxlH EGP Major facilitator Superfamily
FHJKHKDH_02673 7e-136 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
FHJKHKDH_02674 4.8e-165 yxlF V ABC transporter, ATP-binding protein
FHJKHKDH_02675 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
FHJKHKDH_02676 1.2e-31
FHJKHKDH_02677 3.9e-48 yxlC S Family of unknown function (DUF5345)
FHJKHKDH_02678 1.1e-84 sigY K Belongs to the sigma-70 factor family. ECF subfamily
FHJKHKDH_02679 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
FHJKHKDH_02680 5.3e-158 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FHJKHKDH_02681 0.0 cydD V ATP-binding protein
FHJKHKDH_02682 0.0 cydD V ATP-binding
FHJKHKDH_02683 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
FHJKHKDH_02684 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
FHJKHKDH_02685 1.5e-229 cimH C COG3493 Na citrate symporter
FHJKHKDH_02686 1.2e-310 3.4.24.84 O Peptidase family M48
FHJKHKDH_02688 1.6e-154 yxkH G Polysaccharide deacetylase
FHJKHKDH_02689 5.9e-205 msmK P Belongs to the ABC transporter superfamily
FHJKHKDH_02690 1.2e-163 lrp QT PucR C-terminal helix-turn-helix domain
FHJKHKDH_02691 4.1e-270 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
FHJKHKDH_02692 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
FHJKHKDH_02693 1.4e-73 yxkC S Domain of unknown function (DUF4352)
FHJKHKDH_02694 6.7e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
FHJKHKDH_02695 1e-76 S Protein of unknown function (DUF1453)
FHJKHKDH_02696 2.7e-190 yxjM T Signal transduction histidine kinase
FHJKHKDH_02697 3.4e-115 K helix_turn_helix, Lux Regulon
FHJKHKDH_02698 5.2e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
FHJKHKDH_02701 7.1e-86 yxjI S LURP-one-related
FHJKHKDH_02702 7.9e-221 yxjG 2.1.1.14 E Methionine synthase
FHJKHKDH_02703 3.9e-220 yxjG 2.1.1.14 E Methionine synthase
FHJKHKDH_02704 8.2e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
FHJKHKDH_02705 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
FHJKHKDH_02706 6.9e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FHJKHKDH_02707 7.5e-253 yxjC EG COG2610 H gluconate symporter and related permeases
FHJKHKDH_02708 2.9e-159 rlmA 2.1.1.187 Q Methyltransferase domain
FHJKHKDH_02709 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FHJKHKDH_02710 1.5e-102 T Domain of unknown function (DUF4163)
FHJKHKDH_02711 4.3e-46 yxiS
FHJKHKDH_02712 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
FHJKHKDH_02713 4.3e-223 citH C Citrate transporter
FHJKHKDH_02714 2.8e-142 exoK GH16 M licheninase activity
FHJKHKDH_02715 8.3e-151 licT K transcriptional antiterminator
FHJKHKDH_02716 2.4e-111
FHJKHKDH_02717 1.2e-230 yxiO S COG2270 Permeases of the major facilitator superfamily
FHJKHKDH_02718 1.6e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
FHJKHKDH_02719 9.5e-214 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
FHJKHKDH_02720 5e-54 padR K Transcriptional regulator PadR-like family
FHJKHKDH_02721 5.8e-41 S Protein of unknown function (DUF2812)
FHJKHKDH_02722 3.4e-17 S YxiJ-like protein
FHJKHKDH_02723 0.0 wapA M COG3209 Rhs family protein
FHJKHKDH_02724 5.6e-164 yxxF EG EamA-like transporter family
FHJKHKDH_02725 1.3e-18
FHJKHKDH_02726 3.6e-62 K helix_turn_helix, mercury resistance
FHJKHKDH_02727 7.2e-13
FHJKHKDH_02728 8e-89
FHJKHKDH_02729 5.5e-34 S Sporulation delaying protein SdpA
FHJKHKDH_02730 5.4e-72 yxiE T Belongs to the universal stress protein A family
FHJKHKDH_02731 2.1e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FHJKHKDH_02732 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
FHJKHKDH_02733 5.3e-47
FHJKHKDH_02734 2.9e-78 S SMI1 / KNR4 family
FHJKHKDH_02735 3.2e-218 S nuclease activity
FHJKHKDH_02737 7.3e-19 S Protein conserved in bacteria
FHJKHKDH_02739 1e-125 S nuclease activity
FHJKHKDH_02740 2.6e-37 yxiC S Family of unknown function (DUF5344)
FHJKHKDH_02741 4.6e-21 S Domain of unknown function (DUF5082)
FHJKHKDH_02742 5.1e-278 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
FHJKHKDH_02743 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
FHJKHKDH_02744 2.2e-282 hutH 4.3.1.3 E Histidine ammonia-lyase
FHJKHKDH_02745 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FHJKHKDH_02746 2.4e-234 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
FHJKHKDH_02747 5.7e-180 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
FHJKHKDH_02748 6.8e-251 lysP E amino acid
FHJKHKDH_02749 1.3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
FHJKHKDH_02750 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FHJKHKDH_02751 7.7e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FHJKHKDH_02752 7.9e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
FHJKHKDH_02753 9.7e-152 yxxB S Domain of Unknown Function (DUF1206)
FHJKHKDH_02754 1.9e-198 eutH E Ethanolamine utilisation protein, EutH
FHJKHKDH_02755 7.6e-247 yxeQ S MmgE/PrpD family
FHJKHKDH_02756 2.8e-210 yxeP 3.5.1.47 E hydrolase activity
FHJKHKDH_02757 5.9e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
FHJKHKDH_02758 2.7e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
FHJKHKDH_02759 1.2e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
FHJKHKDH_02760 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FHJKHKDH_02761 1.1e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FHJKHKDH_02762 1.9e-186 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
FHJKHKDH_02763 6.2e-151 yidA S hydrolases of the HAD superfamily
FHJKHKDH_02766 1.3e-20 yxeE
FHJKHKDH_02767 5.6e-16 yxeD
FHJKHKDH_02768 8.5e-69
FHJKHKDH_02769 2.5e-175 fhuD P ABC transporter
FHJKHKDH_02770 1.5e-58 yxeA S Protein of unknown function (DUF1093)
FHJKHKDH_02771 0.0 yxdM V ABC transporter (permease)
FHJKHKDH_02772 9.4e-141 yxdL V ABC transporter, ATP-binding protein
FHJKHKDH_02773 4e-181 T PhoQ Sensor
FHJKHKDH_02774 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FHJKHKDH_02775 4.6e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
FHJKHKDH_02776 6.6e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
FHJKHKDH_02777 8.6e-167 iolH G Xylose isomerase-like TIM barrel
FHJKHKDH_02778 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
FHJKHKDH_02779 6.2e-233 iolF EGP Major facilitator Superfamily
FHJKHKDH_02780 8e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
FHJKHKDH_02781 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
FHJKHKDH_02782 6.5e-179 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
FHJKHKDH_02783 1e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
FHJKHKDH_02784 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
FHJKHKDH_02785 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
FHJKHKDH_02786 8.3e-176 iolS C Aldo keto reductase
FHJKHKDH_02788 8.3e-48 yxcD S Protein of unknown function (DUF2653)
FHJKHKDH_02789 6.2e-244 csbC EGP Major facilitator Superfamily
FHJKHKDH_02790 0.0 htpG O Molecular chaperone. Has ATPase activity
FHJKHKDH_02792 2.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
FHJKHKDH_02793 2.7e-208 yxbF K Bacterial regulatory proteins, tetR family
FHJKHKDH_02794 1.3e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
FHJKHKDH_02795 4e-12 yxaI S membrane protein domain
FHJKHKDH_02796 9.9e-92 S PQQ-like domain
FHJKHKDH_02797 5.1e-64 S Family of unknown function (DUF5391)
FHJKHKDH_02798 1.4e-75 yxaI S membrane protein domain
FHJKHKDH_02799 1.6e-227 P Protein of unknown function (DUF418)
FHJKHKDH_02800 3.5e-196 yxaG 1.13.11.24 S AraC-like ligand binding domain
FHJKHKDH_02801 2.7e-100 yxaF K Transcriptional regulator
FHJKHKDH_02802 8e-199 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
FHJKHKDH_02803 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
FHJKHKDH_02804 4.9e-48 S LrgA family
FHJKHKDH_02805 5e-117 yxaC M effector of murein hydrolase
FHJKHKDH_02806 3.7e-193 yxaB GM Polysaccharide pyruvyl transferase
FHJKHKDH_02807 5.6e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
FHJKHKDH_02808 2.1e-126 gntR K transcriptional
FHJKHKDH_02809 3.3e-302 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
FHJKHKDH_02810 1e-230 gntP EG COG2610 H gluconate symporter and related permeases
FHJKHKDH_02811 1.1e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FHJKHKDH_02812 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
FHJKHKDH_02813 5.5e-286 ahpF O Alkyl hydroperoxide reductase
FHJKHKDH_02814 7.3e-189 wgaE S Polysaccharide pyruvyl transferase
FHJKHKDH_02815 4.1e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FHJKHKDH_02816 4.1e-36 bglF G phosphotransferase system
FHJKHKDH_02817 9.3e-127 yydK K Transcriptional regulator
FHJKHKDH_02818 8.4e-12
FHJKHKDH_02819 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
FHJKHKDH_02820 0.0 L AAA domain
FHJKHKDH_02821 3.9e-245 L Uncharacterized conserved protein (DUF2075)
FHJKHKDH_02822 3e-42 S MazG-like family
FHJKHKDH_02823 2e-118 atmc2 S Caspase domain
FHJKHKDH_02824 7.1e-109 L reverse transcriptase
FHJKHKDH_02825 1.2e-19
FHJKHKDH_02826 2e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FHJKHKDH_02827 1.1e-09 S YyzF-like protein
FHJKHKDH_02828 4.4e-68
FHJKHKDH_02829 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
FHJKHKDH_02831 9.7e-31 yycQ S Protein of unknown function (DUF2651)
FHJKHKDH_02832 3.6e-213 yycP
FHJKHKDH_02833 5.8e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
FHJKHKDH_02834 3.8e-84 yycN 2.3.1.128 K Acetyltransferase
FHJKHKDH_02835 8.8e-185 S aspartate phosphatase
FHJKHKDH_02837 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
FHJKHKDH_02838 1.3e-260 rocE E amino acid
FHJKHKDH_02839 7.3e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
FHJKHKDH_02840 4.4e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
FHJKHKDH_02841 4.7e-173 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
FHJKHKDH_02842 1.5e-94 K PFAM response regulator receiver
FHJKHKDH_02843 1.2e-73 S Peptidase propeptide and YPEB domain
FHJKHKDH_02844 1.4e-33 S Peptidase propeptide and YPEB domain
FHJKHKDH_02845 8.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FHJKHKDH_02846 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
FHJKHKDH_02847 1.8e-153 yycI S protein conserved in bacteria
FHJKHKDH_02848 3.4e-258 yycH S protein conserved in bacteria
FHJKHKDH_02849 0.0 vicK 2.7.13.3 T Histidine kinase
FHJKHKDH_02850 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FHJKHKDH_02855 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FHJKHKDH_02856 2.2e-75 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
FHJKHKDH_02857 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
FHJKHKDH_02858 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
FHJKHKDH_02860 1.9e-15 yycC K YycC-like protein
FHJKHKDH_02861 8.4e-221 yeaN P COG2807 Cyanate permease
FHJKHKDH_02862 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FHJKHKDH_02863 2.2e-73 rplI J binds to the 23S rRNA
FHJKHKDH_02864 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
FHJKHKDH_02865 3.2e-159 yybS S membrane
FHJKHKDH_02867 3.9e-84 cotF M Spore coat protein
FHJKHKDH_02868 1.7e-66 ydeP3 K Transcriptional regulator
FHJKHKDH_02869 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
FHJKHKDH_02870 1.5e-58
FHJKHKDH_02872 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
FHJKHKDH_02873 6.3e-110 K TipAS antibiotic-recognition domain
FHJKHKDH_02874 1.1e-123
FHJKHKDH_02875 2.9e-66 yybH S SnoaL-like domain
FHJKHKDH_02876 1.6e-122 yybG S Pentapeptide repeat-containing protein
FHJKHKDH_02877 3.1e-215 ynfM EGP Major facilitator Superfamily
FHJKHKDH_02878 6.9e-164 yybE K Transcriptional regulator
FHJKHKDH_02879 5.5e-77 yjcF S Acetyltransferase (GNAT) domain
FHJKHKDH_02880 2.3e-73 yybC
FHJKHKDH_02881 7.3e-126 S Metallo-beta-lactamase superfamily
FHJKHKDH_02882 5.6e-77 yybA 2.3.1.57 K transcriptional
FHJKHKDH_02883 2e-71 yjcF S Acetyltransferase (GNAT) domain
FHJKHKDH_02884 5.5e-96 yyaS S Membrane
FHJKHKDH_02885 3e-90 yyaR K Acetyltransferase (GNAT) domain
FHJKHKDH_02886 3e-65 yyaQ S YjbR
FHJKHKDH_02887 1e-104 yyaP 1.5.1.3 H RibD C-terminal domain
FHJKHKDH_02888 1.7e-249 tetL EGP Major facilitator Superfamily
FHJKHKDH_02889 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
FHJKHKDH_02890 4e-167 yyaK S CAAX protease self-immunity
FHJKHKDH_02891 6.1e-244 EGP Major facilitator superfamily
FHJKHKDH_02892 8.1e-94 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
FHJKHKDH_02893 1.3e-66 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
FHJKHKDH_02894 1.5e-177 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
FHJKHKDH_02895 1.7e-142 xth 3.1.11.2 L exodeoxyribonuclease III
FHJKHKDH_02896 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FHJKHKDH_02897 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
FHJKHKDH_02898 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
FHJKHKDH_02899 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
FHJKHKDH_02900 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FHJKHKDH_02901 2.3e-33 yyzM S protein conserved in bacteria
FHJKHKDH_02902 8.1e-177 yyaD S Membrane
FHJKHKDH_02903 2.8e-111 yyaC S Sporulation protein YyaC
FHJKHKDH_02904 2.1e-149 spo0J K Belongs to the ParB family
FHJKHKDH_02905 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
FHJKHKDH_02906 9.6e-74 S Bacterial PH domain
FHJKHKDH_02907 5.5e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
FHJKHKDH_02908 5.3e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
FHJKHKDH_02909 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
FHJKHKDH_02910 3.7e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FHJKHKDH_02911 6.5e-108 jag S single-stranded nucleic acid binding R3H
FHJKHKDH_02912 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FHJKHKDH_02913 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
FHJKHKDH_02914 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FHJKHKDH_02915 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
FHJKHKDH_02916 2.4e-33 yaaA S S4 domain
FHJKHKDH_02917 5.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FHJKHKDH_02918 1.8e-37 yaaB S Domain of unknown function (DUF370)
FHJKHKDH_02919 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FHJKHKDH_02920 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FHJKHKDH_02921 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
FHJKHKDH_02922 3.4e-94 M1-753 M FR47-like protein
FHJKHKDH_02923 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
FHJKHKDH_02924 1.2e-75 yuaF OU Membrane protein implicated in regulation of membrane protease activity
FHJKHKDH_02925 3.9e-84 yuaE S DinB superfamily
FHJKHKDH_02926 7.9e-108 yuaD
FHJKHKDH_02927 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
FHJKHKDH_02928 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
FHJKHKDH_02929 1.1e-95 yuaC K Belongs to the GbsR family
FHJKHKDH_02930 2.2e-91 yuaB
FHJKHKDH_02931 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
FHJKHKDH_02932 1.6e-236 ktrB P Potassium
FHJKHKDH_02933 1e-38 yiaA S yiaA/B two helix domain
FHJKHKDH_02934 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
FHJKHKDH_02935 3.2e-273 yubD P Major Facilitator Superfamily
FHJKHKDH_02936 6.4e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
FHJKHKDH_02938 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
FHJKHKDH_02939 4.5e-195 yubA S transporter activity
FHJKHKDH_02940 3.3e-183 ygjR S Oxidoreductase
FHJKHKDH_02941 6.7e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
FHJKHKDH_02942 7.2e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
FHJKHKDH_02943 1.4e-275 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
FHJKHKDH_02944 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
FHJKHKDH_02945 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
FHJKHKDH_02946 7.3e-238 mcpA NT chemotaxis protein
FHJKHKDH_02947 8.5e-295 mcpA NT chemotaxis protein
FHJKHKDH_02948 9.9e-219 mcpA NT chemotaxis protein
FHJKHKDH_02949 9.3e-225 mcpA NT chemotaxis protein
FHJKHKDH_02950 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
FHJKHKDH_02951 2.3e-35
FHJKHKDH_02952 2.1e-72 yugU S Uncharacterised protein family UPF0047
FHJKHKDH_02953 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
FHJKHKDH_02954 8.4e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
FHJKHKDH_02955 1.4e-116 yugP S Zn-dependent protease
FHJKHKDH_02956 2.3e-38
FHJKHKDH_02957 1.1e-53 mstX S Membrane-integrating protein Mistic
FHJKHKDH_02958 8.2e-182 yugO P COG1226 Kef-type K transport systems
FHJKHKDH_02959 1.4e-71 yugN S YugN-like family
FHJKHKDH_02961 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
FHJKHKDH_02962 4e-228 yugK C Dehydrogenase
FHJKHKDH_02963 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
FHJKHKDH_02964 1.1e-34 yuzA S Domain of unknown function (DUF378)
FHJKHKDH_02965 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
FHJKHKDH_02966 6.2e-199 yugH 2.6.1.1 E Aminotransferase
FHJKHKDH_02967 1.6e-85 alaR K Transcriptional regulator
FHJKHKDH_02968 4.9e-156 yugF I Hydrolase
FHJKHKDH_02969 4.6e-39 yugE S Domain of unknown function (DUF1871)
FHJKHKDH_02970 5.4e-225 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
FHJKHKDH_02971 4.6e-233 T PhoQ Sensor
FHJKHKDH_02972 1.8e-68 kapB G Kinase associated protein B
FHJKHKDH_02973 1.9e-115 kapD L the KinA pathway to sporulation
FHJKHKDH_02975 2.1e-183 yuxJ EGP Major facilitator Superfamily
FHJKHKDH_02976 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
FHJKHKDH_02977 6.3e-75 yuxK S protein conserved in bacteria
FHJKHKDH_02978 6.3e-78 yufK S Family of unknown function (DUF5366)
FHJKHKDH_02979 6.4e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
FHJKHKDH_02980 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
FHJKHKDH_02981 4.2e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
FHJKHKDH_02982 1.1e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
FHJKHKDH_02983 2.5e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
FHJKHKDH_02984 1.5e-167 yufQ S Belongs to the binding-protein-dependent transport system permease family
FHJKHKDH_02985 8.2e-233 maeN C COG3493 Na citrate symporter
FHJKHKDH_02986 5e-15
FHJKHKDH_02987 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
FHJKHKDH_02988 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
FHJKHKDH_02989 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
FHJKHKDH_02990 3.5e-261 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
FHJKHKDH_02991 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
FHJKHKDH_02992 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
FHJKHKDH_02993 5.7e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
FHJKHKDH_02994 5.1e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
FHJKHKDH_02995 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FHJKHKDH_02996 0.0 comP 2.7.13.3 T Histidine kinase
FHJKHKDH_02998 2.9e-128 comQ H Belongs to the FPP GGPP synthase family
FHJKHKDH_03000 3.8e-23 yuzC
FHJKHKDH_03001 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
FHJKHKDH_03002 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FHJKHKDH_03003 1.2e-102 pncA Q COG1335 Amidases related to nicotinamidase
FHJKHKDH_03004 5.1e-66 yueI S Protein of unknown function (DUF1694)
FHJKHKDH_03005 7.4e-39 yueH S YueH-like protein
FHJKHKDH_03006 7.8e-32 yueG S Spore germination protein gerPA/gerPF
FHJKHKDH_03007 1.2e-189 yueF S transporter activity
FHJKHKDH_03008 4.4e-70 S Protein of unknown function (DUF2283)
FHJKHKDH_03009 2.9e-24 S Protein of unknown function (DUF2642)
FHJKHKDH_03010 4.8e-96 yueE S phosphohydrolase
FHJKHKDH_03011 8.4e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FHJKHKDH_03012 3.3e-64 yueC S Family of unknown function (DUF5383)
FHJKHKDH_03013 0.0 esaA S type VII secretion protein EsaA
FHJKHKDH_03014 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
FHJKHKDH_03015 1.1e-210 essB S WXG100 protein secretion system (Wss), protein YukC
FHJKHKDH_03016 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
FHJKHKDH_03017 2.8e-45 esxA S Belongs to the WXG100 family
FHJKHKDH_03018 1.5e-228 yukF QT Transcriptional regulator
FHJKHKDH_03019 6.1e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
FHJKHKDH_03020 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
FHJKHKDH_03021 8.5e-36 mbtH S MbtH-like protein
FHJKHKDH_03022 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FHJKHKDH_03023 2e-177 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
FHJKHKDH_03024 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
FHJKHKDH_03025 2.3e-226 entC 5.4.4.2 HQ Isochorismate synthase
FHJKHKDH_03026 3.6e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
FHJKHKDH_03027 9.6e-166 besA S Putative esterase
FHJKHKDH_03028 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
FHJKHKDH_03029 1.1e-93 bioY S Biotin biosynthesis protein
FHJKHKDH_03030 3.9e-211 yuiF S antiporter
FHJKHKDH_03031 3.4e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FHJKHKDH_03032 1.2e-77 yuiD S protein conserved in bacteria
FHJKHKDH_03033 1.1e-116 yuiC S protein conserved in bacteria
FHJKHKDH_03034 3.2e-26 yuiB S Putative membrane protein
FHJKHKDH_03035 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
FHJKHKDH_03036 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
FHJKHKDH_03038 6e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
FHJKHKDH_03039 3.8e-116 paiB K Putative FMN-binding domain
FHJKHKDH_03040 1.4e-71 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FHJKHKDH_03041 3.7e-63 erpA S Belongs to the HesB IscA family
FHJKHKDH_03042 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FHJKHKDH_03043 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FHJKHKDH_03044 3.2e-39 yuzB S Belongs to the UPF0349 family
FHJKHKDH_03045 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
FHJKHKDH_03046 1.1e-55 yuzD S protein conserved in bacteria
FHJKHKDH_03047 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
FHJKHKDH_03048 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
FHJKHKDH_03049 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
FHJKHKDH_03050 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FHJKHKDH_03051 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
FHJKHKDH_03052 2.9e-198 yutH S Spore coat protein
FHJKHKDH_03053 3.3e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
FHJKHKDH_03054 1.2e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
FHJKHKDH_03055 1e-75 yutE S Protein of unknown function DUF86
FHJKHKDH_03056 9.7e-48 yutD S protein conserved in bacteria
FHJKHKDH_03057 2.4e-110 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
FHJKHKDH_03058 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FHJKHKDH_03059 3.8e-195 lytH M Peptidase, M23
FHJKHKDH_03060 3.2e-133 yunB S Sporulation protein YunB (Spo_YunB)
FHJKHKDH_03061 4.8e-48 yunC S Domain of unknown function (DUF1805)
FHJKHKDH_03062 1.4e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
FHJKHKDH_03063 2e-141 yunE S membrane transporter protein
FHJKHKDH_03064 4.3e-171 yunF S Protein of unknown function DUF72
FHJKHKDH_03065 2.8e-60 yunG
FHJKHKDH_03066 7.3e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
FHJKHKDH_03067 7e-300 pucR QT COG2508 Regulator of polyketide synthase expression
FHJKHKDH_03068 2e-234 pbuX F Permease family
FHJKHKDH_03069 9e-221 pbuX F xanthine
FHJKHKDH_03070 3.4e-280 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
FHJKHKDH_03071 2.7e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
FHJKHKDH_03072 1.8e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
FHJKHKDH_03073 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
FHJKHKDH_03074 3.4e-152 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
FHJKHKDH_03075 3.1e-110 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
FHJKHKDH_03076 1e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FHJKHKDH_03077 7.8e-238 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
FHJKHKDH_03078 2.3e-237 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
FHJKHKDH_03079 7.7e-168 bsn L Ribonuclease
FHJKHKDH_03080 5.9e-205 msmX P Belongs to the ABC transporter superfamily
FHJKHKDH_03081 3.3e-135 yurK K UTRA
FHJKHKDH_03082 7.4e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
FHJKHKDH_03083 8.1e-168 yurM P COG0395 ABC-type sugar transport system, permease component
FHJKHKDH_03084 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
FHJKHKDH_03085 2.5e-239 yurO G COG1653 ABC-type sugar transport system, periplasmic component
FHJKHKDH_03086 3.3e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
FHJKHKDH_03087 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
FHJKHKDH_03088 5.1e-204 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
FHJKHKDH_03090 1e-41
FHJKHKDH_03091 3.5e-271 sufB O FeS cluster assembly
FHJKHKDH_03092 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
FHJKHKDH_03093 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FHJKHKDH_03094 5.3e-245 sufD O assembly protein SufD
FHJKHKDH_03095 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
FHJKHKDH_03096 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FHJKHKDH_03097 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
FHJKHKDH_03098 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
FHJKHKDH_03099 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FHJKHKDH_03100 2.4e-56 yusD S SCP-2 sterol transfer family
FHJKHKDH_03101 5.6e-55 traF CO Thioredoxin
FHJKHKDH_03102 2.1e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
FHJKHKDH_03103 1.1e-39 yusG S Protein of unknown function (DUF2553)
FHJKHKDH_03104 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
FHJKHKDH_03105 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
FHJKHKDH_03106 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
FHJKHKDH_03107 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
FHJKHKDH_03108 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
FHJKHKDH_03109 8.1e-09 S YuzL-like protein
FHJKHKDH_03110 2.4e-164 fadM E Proline dehydrogenase
FHJKHKDH_03111 5.1e-40
FHJKHKDH_03112 5.4e-53 yusN M Coat F domain
FHJKHKDH_03113 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
FHJKHKDH_03114 8.5e-293 yusP P Major facilitator superfamily
FHJKHKDH_03115 7.1e-65 yusQ S Tautomerase enzyme
FHJKHKDH_03116 1.3e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
FHJKHKDH_03117 5.7e-158 yusT K LysR substrate binding domain
FHJKHKDH_03118 3.8e-47 yusU S Protein of unknown function (DUF2573)
FHJKHKDH_03119 1e-153 yusV 3.6.3.34 HP ABC transporter
FHJKHKDH_03120 9.6e-66 S YusW-like protein
FHJKHKDH_03121 7.2e-301 pepF2 E COG1164 Oligoendopeptidase F
FHJKHKDH_03122 8.9e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
FHJKHKDH_03123 4.7e-79 dps P Ferritin-like domain
FHJKHKDH_03124 4.7e-236 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FHJKHKDH_03125 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FHJKHKDH_03126 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
FHJKHKDH_03127 4.3e-158 yuxN K Transcriptional regulator
FHJKHKDH_03128 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
FHJKHKDH_03129 2.3e-24 S Protein of unknown function (DUF3970)
FHJKHKDH_03130 3.7e-247 gerAA EG Spore germination protein
FHJKHKDH_03131 9.1e-198 gerAB E Spore germination protein
FHJKHKDH_03132 6e-189 gerAC S Spore germination B3/ GerAC like, C-terminal
FHJKHKDH_03133 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FHJKHKDH_03134 1e-185 vraS 2.7.13.3 T Histidine kinase
FHJKHKDH_03135 1.2e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
FHJKHKDH_03136 1.5e-118 liaG S Putative adhesin
FHJKHKDH_03137 9.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
FHJKHKDH_03138 5.6e-62 liaI S membrane
FHJKHKDH_03139 2.4e-226 yvqJ EGP Major facilitator Superfamily
FHJKHKDH_03140 6.1e-100 yvqK 2.5.1.17 S Adenosyltransferase
FHJKHKDH_03141 1.2e-241 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
FHJKHKDH_03142 2.9e-185 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FHJKHKDH_03143 1e-168 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
FHJKHKDH_03144 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
FHJKHKDH_03145 4.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
FHJKHKDH_03146 0.0 T PhoQ Sensor
FHJKHKDH_03147 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FHJKHKDH_03148 3.6e-22
FHJKHKDH_03149 9.5e-98 yvrI K RNA polymerase
FHJKHKDH_03150 5.2e-19 S YvrJ protein family
FHJKHKDH_03151 4.7e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
FHJKHKDH_03152 8.4e-64 yvrL S Regulatory protein YrvL
FHJKHKDH_03153 5.2e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
FHJKHKDH_03154 7.9e-123 macB V ABC transporter, ATP-binding protein
FHJKHKDH_03155 4.8e-176 M Efflux transporter rnd family, mfp subunit
FHJKHKDH_03156 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
FHJKHKDH_03157 3.8e-174 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FHJKHKDH_03158 2.3e-182 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FHJKHKDH_03159 2e-177 fhuD P ABC transporter
FHJKHKDH_03161 4.9e-236 yvsH E Arginine ornithine antiporter
FHJKHKDH_03162 6.5e-16 S Small spore protein J (Spore_SspJ)
FHJKHKDH_03163 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
FHJKHKDH_03164 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
FHJKHKDH_03165 4.6e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
FHJKHKDH_03166 1.6e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
FHJKHKDH_03167 1.7e-117 modB P COG4149 ABC-type molybdate transport system, permease component
FHJKHKDH_03168 1.1e-155 yvgN S reductase
FHJKHKDH_03169 5.4e-86 yvgO
FHJKHKDH_03170 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
FHJKHKDH_03171 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
FHJKHKDH_03172 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FHJKHKDH_03173 0.0 helD 3.6.4.12 L DNA helicase
FHJKHKDH_03175 1.6e-106 yvgT S membrane
FHJKHKDH_03176 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
FHJKHKDH_03177 1.6e-104 bdbD O Thioredoxin
FHJKHKDH_03178 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
FHJKHKDH_03179 0.0 copA 3.6.3.54 P P-type ATPase
FHJKHKDH_03180 5.9e-29 copZ P Copper resistance protein CopZ
FHJKHKDH_03181 2.2e-48 csoR S transcriptional
FHJKHKDH_03182 5.3e-195 yvaA 1.1.1.371 S Oxidoreductase
FHJKHKDH_03183 7e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FHJKHKDH_03184 0.0 yvaC S Fusaric acid resistance protein-like
FHJKHKDH_03185 5.7e-73 yvaD S Family of unknown function (DUF5360)
FHJKHKDH_03186 1.8e-54 yvaE P Small Multidrug Resistance protein
FHJKHKDH_03187 8.7e-96 K Bacterial regulatory proteins, tetR family
FHJKHKDH_03188 1e-129 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
FHJKHKDH_03190 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FHJKHKDH_03191 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
FHJKHKDH_03192 5.6e-143 est 3.1.1.1 S Carboxylesterase
FHJKHKDH_03193 2.4e-23 secG U Preprotein translocase subunit SecG
FHJKHKDH_03194 3.4e-151 yvaM S Serine aminopeptidase, S33
FHJKHKDH_03195 7.5e-36 yvzC K Transcriptional
FHJKHKDH_03196 4e-69 K transcriptional
FHJKHKDH_03197 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
FHJKHKDH_03198 2.2e-54 yodB K transcriptional
FHJKHKDH_03199 3.8e-203 NT chemotaxis protein
FHJKHKDH_03200 2.4e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
FHJKHKDH_03201 7.2e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
FHJKHKDH_03202 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
FHJKHKDH_03203 7.5e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
FHJKHKDH_03204 3.3e-60 yvbF K Belongs to the GbsR family
FHJKHKDH_03205 1.1e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
FHJKHKDH_03206 2.3e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
FHJKHKDH_03207 2.3e-111 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
FHJKHKDH_03208 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
FHJKHKDH_03209 3.5e-97 yvbF K Belongs to the GbsR family
FHJKHKDH_03210 2.4e-102 yvbG U UPF0056 membrane protein
FHJKHKDH_03211 6.2e-111 yvbH S YvbH-like oligomerisation region
FHJKHKDH_03212 3e-122 exoY M Membrane
FHJKHKDH_03213 0.0 tcaA S response to antibiotic
FHJKHKDH_03214 1.3e-81 yvbK 3.1.3.25 K acetyltransferase
FHJKHKDH_03215 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
FHJKHKDH_03216 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
FHJKHKDH_03217 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
FHJKHKDH_03218 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
FHJKHKDH_03219 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
FHJKHKDH_03220 1.8e-184 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
FHJKHKDH_03221 1.6e-252 araE EGP Major facilitator Superfamily
FHJKHKDH_03222 5.5e-203 araR K transcriptional
FHJKHKDH_03223 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FHJKHKDH_03225 4.3e-158 yvbU K Transcriptional regulator
FHJKHKDH_03226 7.2e-156 yvbV EG EamA-like transporter family
FHJKHKDH_03227 3.7e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
FHJKHKDH_03228 1.6e-191 yvbX S Glycosyl hydrolase
FHJKHKDH_03229 3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
FHJKHKDH_03230 2.7e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
FHJKHKDH_03231 2.2e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
FHJKHKDH_03232 3.8e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FHJKHKDH_03233 4.3e-195 desK 2.7.13.3 T Histidine kinase
FHJKHKDH_03234 1.1e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
FHJKHKDH_03235 1.9e-161 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
FHJKHKDH_03236 9.8e-157 rsbQ S Alpha/beta hydrolase family
FHJKHKDH_03237 5.9e-198 rsbU 3.1.3.3 T response regulator
FHJKHKDH_03238 3.2e-250 galA 3.2.1.89 G arabinogalactan
FHJKHKDH_03239 0.0 lacA 3.2.1.23 G beta-galactosidase
FHJKHKDH_03240 7.2e-150 ganQ P transport
FHJKHKDH_03241 1.1e-231 malC P COG1175 ABC-type sugar transport systems, permease components
FHJKHKDH_03242 1.9e-231 cycB G COG2182 Maltose-binding periplasmic proteins domains
FHJKHKDH_03243 1.8e-184 lacR K Transcriptional regulator
FHJKHKDH_03244 1e-112 yvfI K COG2186 Transcriptional regulators
FHJKHKDH_03245 8.2e-307 yvfH C L-lactate permease
FHJKHKDH_03246 2.3e-240 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
FHJKHKDH_03247 1e-31 yvfG S YvfG protein
FHJKHKDH_03248 1.7e-187 yvfF GM Exopolysaccharide biosynthesis protein
FHJKHKDH_03249 2.5e-222 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
FHJKHKDH_03250 1e-55 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
FHJKHKDH_03251 1.1e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
FHJKHKDH_03252 1.8e-257 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
FHJKHKDH_03253 1.3e-193 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
FHJKHKDH_03254 9.5e-200 epsI GM pyruvyl transferase
FHJKHKDH_03255 4.4e-194 epsH GT2 S Glycosyltransferase like family 2
FHJKHKDH_03256 1.1e-206 epsG S EpsG family
FHJKHKDH_03257 1.4e-217 epsF GT4 M Glycosyl transferases group 1
FHJKHKDH_03258 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
FHJKHKDH_03259 5.2e-220 epsD GT4 M Glycosyl transferase 4-like
FHJKHKDH_03260 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
FHJKHKDH_03261 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
FHJKHKDH_03262 4.4e-121 ywqC M biosynthesis protein
FHJKHKDH_03263 6.3e-76 slr K transcriptional
FHJKHKDH_03264 2.5e-283 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
FHJKHKDH_03266 1.7e-92 padC Q Phenolic acid decarboxylase
FHJKHKDH_03267 5.8e-74 MA20_18690 S Protein of unknown function (DUF3237)
FHJKHKDH_03268 2.4e-124 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
FHJKHKDH_03269 3.5e-260 pbpE V Beta-lactamase
FHJKHKDH_03270 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
FHJKHKDH_03271 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
FHJKHKDH_03272 1.8e-295 yveA E amino acid
FHJKHKDH_03273 2.6e-106 yvdT K Transcriptional regulator
FHJKHKDH_03274 1.5e-50 ykkC P Small Multidrug Resistance protein
FHJKHKDH_03275 4.1e-50 sugE P Small Multidrug Resistance protein
FHJKHKDH_03276 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
FHJKHKDH_03277 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
FHJKHKDH_03278 1.2e-182 S Patatin-like phospholipase
FHJKHKDH_03280 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
FHJKHKDH_03281 3.9e-122 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
FHJKHKDH_03282 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
FHJKHKDH_03283 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
FHJKHKDH_03284 3.8e-154 malA S Protein of unknown function (DUF1189)
FHJKHKDH_03285 3.9e-148 malD P transport
FHJKHKDH_03286 2e-244 malC P COG1175 ABC-type sugar transport systems, permease components
FHJKHKDH_03287 7.8e-08
FHJKHKDH_03289 9e-181 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FHJKHKDH_03290 2.6e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
FHJKHKDH_03291 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
FHJKHKDH_03292 3.1e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
FHJKHKDH_03293 3.9e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FHJKHKDH_03294 0.0 ydiF S ABC transporter
FHJKHKDH_03295 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
FHJKHKDH_03296 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FHJKHKDH_03297 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
FHJKHKDH_03298 1.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FHJKHKDH_03299 2.9e-27 ydiK S Domain of unknown function (DUF4305)
FHJKHKDH_03300 7.9e-129 ydiL S CAAX protease self-immunity
FHJKHKDH_03301 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FHJKHKDH_03302 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
FHJKHKDH_03304 4.1e-40
FHJKHKDH_03305 5.4e-235 yobL S Bacterial EndoU nuclease
FHJKHKDH_03308 5.1e-64 yozB S Membrane
FHJKHKDH_03309 8.8e-26 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
FHJKHKDH_03310 0.0 K NB-ARC domain
FHJKHKDH_03311 1.9e-200 gutB 1.1.1.14 E Dehydrogenase
FHJKHKDH_03312 6.7e-254 gutA G MFS/sugar transport protein
FHJKHKDH_03313 1.5e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
FHJKHKDH_03314 1.1e-113 pspA KT Phage shock protein A
FHJKHKDH_03315 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FHJKHKDH_03316 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
FHJKHKDH_03317 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
FHJKHKDH_03318 4.7e-196 S Ion transport 2 domain protein
FHJKHKDH_03319 2.7e-258 iolT EGP Major facilitator Superfamily
FHJKHKDH_03320 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
FHJKHKDH_03321 4.5e-64 ydjM M Lytic transglycolase
FHJKHKDH_03322 9.7e-149 ydjN U Involved in the tonB-independent uptake of proteins
FHJKHKDH_03324 1.4e-34 ydjO S Cold-inducible protein YdjO
FHJKHKDH_03325 9.5e-160 ydjP I Alpha/beta hydrolase family
FHJKHKDH_03326 2.4e-181 yeaA S Protein of unknown function (DUF4003)
FHJKHKDH_03327 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
FHJKHKDH_03328 4.4e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
FHJKHKDH_03329 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FHJKHKDH_03330 1.7e-176 yeaC S COG0714 MoxR-like ATPases
FHJKHKDH_03331 1.4e-223 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
FHJKHKDH_03332 0.0 yebA E COG1305 Transglutaminase-like enzymes
FHJKHKDH_03333 3.7e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
FHJKHKDH_03334 5.1e-211 pbuG S permease
FHJKHKDH_03335 2.4e-115 yebC M Membrane
FHJKHKDH_03337 4e-93 yebE S UPF0316 protein
FHJKHKDH_03338 8e-28 yebG S NETI protein
FHJKHKDH_03339 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FHJKHKDH_03340 3.3e-214 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FHJKHKDH_03341 2.1e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FHJKHKDH_03342 4.9e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
FHJKHKDH_03343 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FHJKHKDH_03344 1.9e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FHJKHKDH_03345 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FHJKHKDH_03346 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FHJKHKDH_03347 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
FHJKHKDH_03348 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FHJKHKDH_03349 3.9e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
FHJKHKDH_03350 2e-233 purD 6.3.4.13 F Belongs to the GARS family
FHJKHKDH_03351 3.9e-72 K helix_turn_helix ASNC type
FHJKHKDH_03352 6.8e-229 yjeH E Amino acid permease
FHJKHKDH_03353 2.7e-27 S Protein of unknown function (DUF2892)
FHJKHKDH_03354 0.0 yerA 3.5.4.2 F adenine deaminase
FHJKHKDH_03355 5.4e-189 yerB S Protein of unknown function (DUF3048) C-terminal domain
FHJKHKDH_03356 4.8e-51 yerC S protein conserved in bacteria
FHJKHKDH_03357 2e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
FHJKHKDH_03359 3.2e-124 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
FHJKHKDH_03360 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
FHJKHKDH_03361 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FHJKHKDH_03362 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
FHJKHKDH_03363 3.5e-196 yerI S homoserine kinase type II (protein kinase fold)
FHJKHKDH_03364 1.6e-123 sapB S MgtC SapB transporter
FHJKHKDH_03365 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FHJKHKDH_03366 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FHJKHKDH_03367 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
FHJKHKDH_03368 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FHJKHKDH_03369 2.5e-147 yerO K Transcriptional regulator
FHJKHKDH_03370 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FHJKHKDH_03371 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
FHJKHKDH_03372 7.8e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FHJKHKDH_03373 5.6e-296 bcgIA 2.1.1.72 V Type I restriction-modification system methyltransferase subunit()
FHJKHKDH_03374 2e-77 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
FHJKHKDH_03377 4.8e-101 S response regulator aspartate phosphatase
FHJKHKDH_03379 4.9e-30 S Colicin immunity protein / pyocin immunity protein
FHJKHKDH_03381 1.4e-79 S Protein of unknown function, DUF600
FHJKHKDH_03382 8.1e-58 S Protein of unknown function, DUF600
FHJKHKDH_03383 0.0 L nucleic acid phosphodiester bond hydrolysis
FHJKHKDH_03384 2e-183 3.4.24.40 CO amine dehydrogenase activity
FHJKHKDH_03385 2.8e-210 S Tetratricopeptide repeat
FHJKHKDH_03387 9.4e-127 yeeN K transcriptional regulatory protein
FHJKHKDH_03389 8e-100 dhaR3 K Transcriptional regulator
FHJKHKDH_03390 2.8e-81 yesE S SnoaL-like domain
FHJKHKDH_03391 1.3e-151 yesF GM NAD(P)H-binding
FHJKHKDH_03392 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
FHJKHKDH_03393 1.5e-45 cotJB S CotJB protein
FHJKHKDH_03394 5.2e-104 cotJC P Spore Coat
FHJKHKDH_03395 3e-101 yesJ K Acetyltransferase (GNAT) family
FHJKHKDH_03396 9.2e-102 yesL S Protein of unknown function, DUF624
FHJKHKDH_03397 0.0 yesM 2.7.13.3 T Histidine kinase
FHJKHKDH_03398 6.8e-201 yesN K helix_turn_helix, arabinose operon control protein
FHJKHKDH_03399 6.2e-246 yesO G Bacterial extracellular solute-binding protein
FHJKHKDH_03400 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
FHJKHKDH_03401 1.2e-163 yesQ P Binding-protein-dependent transport system inner membrane component
FHJKHKDH_03402 7.8e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
FHJKHKDH_03403 0.0 yesS K Transcriptional regulator
FHJKHKDH_03404 1.2e-131 E GDSL-like Lipase/Acylhydrolase
FHJKHKDH_03405 1.9e-126 yesU S Domain of unknown function (DUF1961)
FHJKHKDH_03406 6.3e-111 yesV S Protein of unknown function, DUF624
FHJKHKDH_03407 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
FHJKHKDH_03408 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
FHJKHKDH_03409 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
FHJKHKDH_03410 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
FHJKHKDH_03411 0.0 yetA
FHJKHKDH_03412 4e-289 lplA G Bacterial extracellular solute-binding protein
FHJKHKDH_03413 3.2e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
FHJKHKDH_03414 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
FHJKHKDH_03415 1.2e-252 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
FHJKHKDH_03416 8.8e-122 yetF S membrane
FHJKHKDH_03417 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
FHJKHKDH_03418 2.6e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
FHJKHKDH_03419 2.2e-34
FHJKHKDH_03420 2.4e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
FHJKHKDH_03421 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
FHJKHKDH_03422 4.5e-104 yetJ S Belongs to the BI1 family
FHJKHKDH_03423 1.4e-89 yetL K helix_turn_helix multiple antibiotic resistance protein
FHJKHKDH_03424 4e-209 yetM CH FAD binding domain
FHJKHKDH_03425 1.7e-133 M Membrane
FHJKHKDH_03426 3.7e-196 yetN S Protein of unknown function (DUF3900)
FHJKHKDH_03427 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
FHJKHKDH_03428 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
FHJKHKDH_03429 1.1e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
FHJKHKDH_03430 3.2e-172 yfnG 4.2.1.45 M dehydratase
FHJKHKDH_03431 1.1e-180 yfnF M Nucleotide-diphospho-sugar transferase
FHJKHKDH_03432 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
FHJKHKDH_03433 3.5e-190 yfnD M Nucleotide-diphospho-sugar transferase
FHJKHKDH_03434 2e-206 fsr P COG0477 Permeases of the major facilitator superfamily
FHJKHKDH_03435 7.8e-134 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
FHJKHKDH_03436 6.4e-241 yfnA E amino acid
FHJKHKDH_03437 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
FHJKHKDH_03438 1.1e-113 yfmS NT chemotaxis protein
FHJKHKDH_03439 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
FHJKHKDH_03440 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
FHJKHKDH_03441 2.8e-70 yfmP K transcriptional
FHJKHKDH_03442 4.3e-209 yfmO EGP Major facilitator Superfamily
FHJKHKDH_03443 7.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
FHJKHKDH_03444 2.9e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
FHJKHKDH_03445 3.1e-80 yfmK 2.3.1.128 K acetyltransferase
FHJKHKDH_03446 9.4e-189 yfmJ S N-terminal domain of oxidoreductase
FHJKHKDH_03447 7.7e-214 G Major Facilitator Superfamily
FHJKHKDH_03448 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
FHJKHKDH_03449 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
FHJKHKDH_03450 4.7e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FHJKHKDH_03451 1.2e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FHJKHKDH_03452 8.5e-168 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
FHJKHKDH_03453 2.9e-24 S Protein of unknown function (DUF3212)
FHJKHKDH_03454 7.6e-58 yflT S Heat induced stress protein YflT
FHJKHKDH_03455 2.5e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
FHJKHKDH_03456 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
FHJKHKDH_03457 1e-290 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
FHJKHKDH_03458 8.9e-119 citT T response regulator
FHJKHKDH_03459 3e-181 yflP S Tripartite tricarboxylate transporter family receptor
FHJKHKDH_03460 8.5e-227 citM C Citrate transporter
FHJKHKDH_03461 1.6e-151 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
FHJKHKDH_03462 4.3e-216 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FHJKHKDH_03463 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
FHJKHKDH_03464 9.9e-123 yflK S protein conserved in bacteria
FHJKHKDH_03465 4e-18 yflJ S Protein of unknown function (DUF2639)
FHJKHKDH_03466 5.4e-19 yflI
FHJKHKDH_03467 5.3e-50 yflH S Protein of unknown function (DUF3243)
FHJKHKDH_03468 4.2e-138 map 3.4.11.18 E Methionine aminopeptidase
FHJKHKDH_03469 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
FHJKHKDH_03470 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
FHJKHKDH_03471 6e-67 yhdN S Domain of unknown function (DUF1992)
FHJKHKDH_03472 2.2e-252 agcS_1 E Sodium alanine symporter
FHJKHKDH_03473 1.6e-194 E Spore germination protein
FHJKHKDH_03475 1.5e-206 yfkR S spore germination
FHJKHKDH_03476 2.9e-282 yfkQ EG Spore germination protein
FHJKHKDH_03477 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
FHJKHKDH_03478 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
FHJKHKDH_03479 1.8e-133 treR K transcriptional
FHJKHKDH_03480 1.6e-125 yfkO C nitroreductase
FHJKHKDH_03481 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
FHJKHKDH_03482 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
FHJKHKDH_03483 6.8e-207 ydiM EGP Major facilitator Superfamily
FHJKHKDH_03484 2.1e-29 yfkK S Belongs to the UPF0435 family
FHJKHKDH_03485 2.2e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FHJKHKDH_03486 8.4e-51 yfkI S gas vesicle protein
FHJKHKDH_03487 9.7e-144 yihY S Belongs to the UPF0761 family
FHJKHKDH_03488 5e-08
FHJKHKDH_03489 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
FHJKHKDH_03490 1e-182 cax P COG0387 Ca2 H antiporter
FHJKHKDH_03491 1.2e-146 yfkD S YfkD-like protein
FHJKHKDH_03492 6e-149 yfkC M Mechanosensitive ion channel
FHJKHKDH_03493 2.1e-221 yfkA S YfkB-like domain
FHJKHKDH_03494 1.1e-26 yfjT
FHJKHKDH_03495 9.9e-154 pdaA G deacetylase
FHJKHKDH_03496 1.7e-146 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
FHJKHKDH_03497 1.7e-184 corA P Mediates influx of magnesium ions
FHJKHKDH_03498 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FHJKHKDH_03499 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FHJKHKDH_03500 3.9e-44 S YfzA-like protein
FHJKHKDH_03501 1.5e-191 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FHJKHKDH_03502 3.9e-86 yfjM S Psort location Cytoplasmic, score
FHJKHKDH_03503 3.7e-190 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
FHJKHKDH_03504 1.9e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
FHJKHKDH_03505 1.1e-193 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
FHJKHKDH_03506 1.2e-255 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
FHJKHKDH_03507 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
FHJKHKDH_03508 9.8e-25 sspH S Belongs to the SspH family
FHJKHKDH_03509 4e-56 yfjF S UPF0060 membrane protein
FHJKHKDH_03510 1.8e-85 S Family of unknown function (DUF5381)
FHJKHKDH_03511 5.6e-125 yfjC
FHJKHKDH_03512 1.2e-171 yfjB
FHJKHKDH_03513 3.3e-44 yfjA S Belongs to the WXG100 family
FHJKHKDH_03514 1.9e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
FHJKHKDH_03515 3e-139 glvR K Helix-turn-helix domain, rpiR family
FHJKHKDH_03516 1.8e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
FHJKHKDH_03517 0.0 yobO M COG5434 Endopolygalacturonase
FHJKHKDH_03518 2.2e-307 yfiB3 V ABC transporter
FHJKHKDH_03519 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
FHJKHKDH_03520 6.4e-64 mhqP S DoxX
FHJKHKDH_03521 5.7e-163 yfiE 1.13.11.2 S glyoxalase
FHJKHKDH_03523 3.4e-211 yxjM T Histidine kinase
FHJKHKDH_03524 5.4e-113 KT LuxR family transcriptional regulator
FHJKHKDH_03525 8.9e-170 V ABC transporter, ATP-binding protein
FHJKHKDH_03526 6.8e-207 V ABC-2 family transporter protein
FHJKHKDH_03527 3.8e-202 V COG0842 ABC-type multidrug transport system, permease component
FHJKHKDH_03528 8.3e-99 padR K transcriptional
FHJKHKDH_03529 1.7e-79 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
FHJKHKDH_03530 8.4e-196 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
FHJKHKDH_03531 1.2e-99 yfiT S Belongs to the metal hydrolase YfiT family
FHJKHKDH_03532 3.8e-282 yfiU EGP Major facilitator Superfamily
FHJKHKDH_03533 4.9e-79 yfiV K transcriptional
FHJKHKDH_03534 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FHJKHKDH_03535 8.2e-174 yfiY P ABC transporter substrate-binding protein
FHJKHKDH_03536 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FHJKHKDH_03537 6.8e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FHJKHKDH_03538 1.8e-167 yfhB 5.3.3.17 S PhzF family
FHJKHKDH_03539 3.9e-107 yfhC C nitroreductase
FHJKHKDH_03540 2.1e-25 yfhD S YfhD-like protein
FHJKHKDH_03542 3.5e-171 yfhF S nucleoside-diphosphate sugar epimerase
FHJKHKDH_03543 2.5e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
FHJKHKDH_03544 3.2e-50 yfhH S Protein of unknown function (DUF1811)
FHJKHKDH_03545 1.5e-209 yfhI EGP Major facilitator Superfamily
FHJKHKDH_03546 6.2e-20 sspK S reproduction
FHJKHKDH_03547 1.3e-44 yfhJ S WVELL protein
FHJKHKDH_03548 5.1e-90 batE T Bacterial SH3 domain homologues
FHJKHKDH_03549 3e-47 yfhL S SdpI/YhfL protein family
FHJKHKDH_03550 4.4e-171 yfhM S Alpha beta hydrolase
FHJKHKDH_03551 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
FHJKHKDH_03552 0.0 yfhO S Bacterial membrane protein YfhO
FHJKHKDH_03553 5.5e-186 yfhP S membrane-bound metal-dependent
FHJKHKDH_03554 1e-211 mutY L A G-specific
FHJKHKDH_03555 6.9e-36 yfhS
FHJKHKDH_03556 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FHJKHKDH_03557 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
FHJKHKDH_03558 4.9e-48 ygaB S YgaB-like protein
FHJKHKDH_03559 1.3e-104 ygaC J Belongs to the UPF0374 family
FHJKHKDH_03560 1.8e-301 ygaD V ABC transporter
FHJKHKDH_03561 8.7e-180 ygaE S Membrane
FHJKHKDH_03562 1.5e-244 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
FHJKHKDH_03563 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
FHJKHKDH_03564 4e-80 perR P Belongs to the Fur family
FHJKHKDH_03565 1.8e-54 ygzB S UPF0295 protein
FHJKHKDH_03566 6.7e-167 ygxA S Nucleotidyltransferase-like
FHJKHKDH_03567 4.1e-245 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FHJKHKDH_03568 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
FHJKHKDH_03569 2.9e-139 srfAD Q thioesterase
FHJKHKDH_03570 6.1e-227 EGP Major Facilitator Superfamily
FHJKHKDH_03571 5.3e-85 S YcxB-like protein
FHJKHKDH_03572 6.4e-160 ycxC EG EamA-like transporter family
FHJKHKDH_03573 2.1e-252 ycxD K GntR family transcriptional regulator
FHJKHKDH_03574 1.7e-114 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
FHJKHKDH_03575 1.7e-114 yczE S membrane
FHJKHKDH_03576 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
FHJKHKDH_03577 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
FHJKHKDH_03578 1.1e-139 tcyA ET Belongs to the bacterial solute-binding protein 3 family
FHJKHKDH_03579 1.9e-161 bsdA K LysR substrate binding domain
FHJKHKDH_03580 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
FHJKHKDH_03581 1.2e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
FHJKHKDH_03582 4e-39 bsdD 4.1.1.61 S response to toxic substance
FHJKHKDH_03583 1.1e-80 yclD
FHJKHKDH_03584 1.5e-155 yclE 3.4.11.5 S Alpha beta hydrolase
FHJKHKDH_03585 9.5e-267 dtpT E amino acid peptide transporter
FHJKHKDH_03586 7.7e-308 yclG M Pectate lyase superfamily protein
FHJKHKDH_03588 4.4e-281 gerKA EG Spore germination protein
FHJKHKDH_03589 1.3e-232 gerKC S spore germination
FHJKHKDH_03590 9.9e-200 gerKB F Spore germination protein
FHJKHKDH_03591 3.9e-122 yclH P ABC transporter
FHJKHKDH_03592 3.9e-204 yclI V ABC transporter (permease) YclI
FHJKHKDH_03593 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FHJKHKDH_03594 8.3e-260 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
FHJKHKDH_03595 5.2e-71 S aspartate phosphatase
FHJKHKDH_03598 5.9e-239 lysC 2.7.2.4 E Belongs to the aspartokinase family
FHJKHKDH_03599 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FHJKHKDH_03600 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FHJKHKDH_03601 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
FHJKHKDH_03602 9.4e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
FHJKHKDH_03603 4.9e-75 V Restriction endonuclease
FHJKHKDH_03604 1.4e-251 ycnB EGP Major facilitator Superfamily
FHJKHKDH_03605 5.5e-153 ycnC K Transcriptional regulator
FHJKHKDH_03606 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
FHJKHKDH_03607 1.6e-45 ycnE S Monooxygenase
FHJKHKDH_03608 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
FHJKHKDH_03609 1.5e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
FHJKHKDH_03610 3.1e-245 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FHJKHKDH_03611 3.8e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
FHJKHKDH_03612 6.1e-149 glcU U Glucose uptake
FHJKHKDH_03613 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FHJKHKDH_03614 1.4e-99 ycnI S protein conserved in bacteria
FHJKHKDH_03615 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
FHJKHKDH_03616 4.3e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
FHJKHKDH_03617 7.3e-56
FHJKHKDH_03618 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
FHJKHKDH_03619 5.7e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
FHJKHKDH_03620 1.5e-208 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
FHJKHKDH_03621 4.7e-199 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
FHJKHKDH_03622 4.1e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
FHJKHKDH_03623 1.3e-75 sipT 3.4.21.89 U Belongs to the peptidase S26 family
FHJKHKDH_03624 6.8e-110 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
FHJKHKDH_03625 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
FHJKHKDH_03627 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
FHJKHKDH_03628 2.7e-140 ycsF S Belongs to the UPF0271 (lamB) family
FHJKHKDH_03629 2.1e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
FHJKHKDH_03630 2.5e-15 ycsI S Belongs to the D-glutamate cyclase family
FHJKHKDH_03631 5e-113 ycsI S Belongs to the D-glutamate cyclase family
FHJKHKDH_03632 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
FHJKHKDH_03633 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
FHJKHKDH_03634 1.2e-132 kipR K Transcriptional regulator
FHJKHKDH_03635 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
FHJKHKDH_03637 1.4e-49 yczJ S biosynthesis
FHJKHKDH_03638 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
FHJKHKDH_03639 8.3e-173 ydhF S Oxidoreductase
FHJKHKDH_03640 0.0 mtlR K transcriptional regulator, MtlR
FHJKHKDH_03641 2.1e-293 ydaB IQ acyl-CoA ligase
FHJKHKDH_03642 9e-99 ydaC Q Methyltransferase domain
FHJKHKDH_03643 3.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FHJKHKDH_03644 3e-95 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
FHJKHKDH_03645 6.1e-102 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
FHJKHKDH_03646 2.6e-76 ydaG 1.4.3.5 S general stress protein
FHJKHKDH_03647 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
FHJKHKDH_03648 2.5e-46 ydzA EGP Major facilitator Superfamily
FHJKHKDH_03649 2.5e-74 lrpC K Transcriptional regulator
FHJKHKDH_03650 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FHJKHKDH_03651 4.2e-203 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
FHJKHKDH_03652 1.2e-149 ydaK T Diguanylate cyclase, GGDEF domain
FHJKHKDH_03653 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
FHJKHKDH_03654 4.5e-233 ydaM M Glycosyl transferase family group 2
FHJKHKDH_03655 0.0 ydaN S Bacterial cellulose synthase subunit
FHJKHKDH_03656 0.0 ydaO E amino acid
FHJKHKDH_03657 3.3e-77 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
FHJKHKDH_03658 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
FHJKHKDH_03660 2.1e-39
FHJKHKDH_03661 5e-224 mntH P H( )-stimulated, divalent metal cation uptake system
FHJKHKDH_03663 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
FHJKHKDH_03664 1.2e-146 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
FHJKHKDH_03666 8.9e-59 ydbB G Cupin domain
FHJKHKDH_03667 1.8e-62 ydbC S Domain of unknown function (DUF4937
FHJKHKDH_03668 5.1e-153 ydbD P Catalase
FHJKHKDH_03669 2.5e-197 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
FHJKHKDH_03670 4.8e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
FHJKHKDH_03671 1.8e-119 dctR T COG4565 Response regulator of citrate malate metabolism
FHJKHKDH_03672 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
FHJKHKDH_03673 9.7e-181 ydbI S AI-2E family transporter
FHJKHKDH_03674 4.7e-171 ydbJ V ABC transporter, ATP-binding protein
FHJKHKDH_03675 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
FHJKHKDH_03676 1e-51 ydbL
FHJKHKDH_03677 5.2e-220 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
FHJKHKDH_03678 1.1e-18 S Fur-regulated basic protein B
FHJKHKDH_03679 2.2e-07 S Fur-regulated basic protein A
FHJKHKDH_03680 5.6e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FHJKHKDH_03681 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
FHJKHKDH_03682 5.1e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
FHJKHKDH_03683 4.1e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
FHJKHKDH_03684 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
FHJKHKDH_03685 2.1e-82 ydbS S Bacterial PH domain
FHJKHKDH_03686 2.5e-259 ydbT S Membrane
FHJKHKDH_03687 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
FHJKHKDH_03688 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
FHJKHKDH_03689 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
FHJKHKDH_03690 2.3e-223 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FHJKHKDH_03691 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
FHJKHKDH_03692 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
FHJKHKDH_03693 1.3e-143 rsbR T Positive regulator of sigma-B
FHJKHKDH_03694 1.5e-56 rsbS T antagonist
FHJKHKDH_03695 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
FHJKHKDH_03696 7.1e-189 rsbU 3.1.3.3 KT phosphatase
FHJKHKDH_03697 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
FHJKHKDH_03698 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
FHJKHKDH_03699 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FHJKHKDH_03700 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
FHJKHKDH_03704 1.5e-82 ydcG S EVE domain
FHJKHKDH_03705 1.6e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
FHJKHKDH_03706 0.0 yhgF K COG2183 Transcriptional accessory protein
FHJKHKDH_03707 2.6e-82 ydcK S Belongs to the SprT family
FHJKHKDH_03715 2.3e-72 rimJ2 J Acetyltransferase (GNAT) domain
FHJKHKDH_03716 4.2e-44
FHJKHKDH_03717 1.8e-20 S LXG domain of WXG superfamily
FHJKHKDH_03718 8.1e-24 L HNH endonuclease
FHJKHKDH_03719 6.4e-45 L HNH nucleases
FHJKHKDH_03722 8e-10
FHJKHKDH_03725 5.6e-34 K Helix-turn-helix XRE-family like proteins
FHJKHKDH_03726 2.5e-40
FHJKHKDH_03730 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
FHJKHKDH_03731 8.7e-30 cspL K Cold shock
FHJKHKDH_03732 3e-78 carD K Transcription factor
FHJKHKDH_03733 2.1e-144 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
FHJKHKDH_03734 3.6e-165 rhaS5 K AraC-like ligand binding domain
FHJKHKDH_03735 3.4e-172 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
FHJKHKDH_03736 6.9e-164 ydeE K AraC family transcriptional regulator
FHJKHKDH_03737 1.7e-262 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
FHJKHKDH_03738 1.2e-217 ydeG EGP Major facilitator superfamily
FHJKHKDH_03739 1.4e-44 ydeH
FHJKHKDH_03740 6.4e-105 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
FHJKHKDH_03741 6.9e-108
FHJKHKDH_03742 5.8e-77 ksgA1 I Ribosomal RNA adenine dimethylase
FHJKHKDH_03743 2.5e-113 T Transcriptional regulator
FHJKHKDH_03744 1.4e-139 T PhoQ Sensor
FHJKHKDH_03745 2.4e-70 S SNARE associated Golgi protein
FHJKHKDH_03746 1.8e-14 ptsH G PTS HPr component phosphorylation site
FHJKHKDH_03747 2.3e-85 K Transcriptional regulator C-terminal region
FHJKHKDH_03749 6.6e-151 ydeK EG -transporter
FHJKHKDH_03750 6e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
FHJKHKDH_03751 1e-72 maoC I N-terminal half of MaoC dehydratase
FHJKHKDH_03752 1.2e-103 ydeN S Serine hydrolase
FHJKHKDH_03753 1.2e-55 K HxlR-like helix-turn-helix
FHJKHKDH_03754 3.9e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
FHJKHKDH_03755 1.8e-68 ydeP K Transcriptional regulator
FHJKHKDH_03756 1.9e-109 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
FHJKHKDH_03757 2.8e-184 ydeR EGP Major facilitator Superfamily
FHJKHKDH_03758 1e-102 ydeS K Transcriptional regulator
FHJKHKDH_03759 2.8e-57 arsR K transcriptional
FHJKHKDH_03760 3.7e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FHJKHKDH_03761 3.4e-146 ydfB J GNAT acetyltransferase
FHJKHKDH_03762 9.8e-153 ydfC EG EamA-like transporter family
FHJKHKDH_03763 3e-273 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
FHJKHKDH_03764 2.1e-114 ydfE S Flavin reductase like domain
FHJKHKDH_03765 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
FHJKHKDH_03766 1e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FHJKHKDH_03768 1.8e-175 ydfH 2.7.13.3 T Histidine kinase
FHJKHKDH_03769 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FHJKHKDH_03770 0.0 ydfJ S drug exporters of the RND superfamily
FHJKHKDH_03771 5.6e-146 S Alpha/beta hydrolase family
FHJKHKDH_03772 3.1e-10 S Alpha/beta hydrolase family
FHJKHKDH_03773 7.2e-116 S Protein of unknown function (DUF554)
FHJKHKDH_03774 1.3e-145 K Bacterial transcription activator, effector binding domain
FHJKHKDH_03775 7.8e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FHJKHKDH_03776 2.8e-111 ydfN C nitroreductase
FHJKHKDH_03777 7.6e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
FHJKHKDH_03778 8.8e-63 mhqP S DoxX
FHJKHKDH_03779 4.5e-55 traF CO Thioredoxin
FHJKHKDH_03780 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
FHJKHKDH_03781 6.3e-29
FHJKHKDH_03783 4.4e-118 ydfR S Protein of unknown function (DUF421)
FHJKHKDH_03784 1.5e-121 ydfS S Protein of unknown function (DUF421)
FHJKHKDH_03785 2.2e-75 cotP O Belongs to the small heat shock protein (HSP20) family
FHJKHKDH_03786 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
FHJKHKDH_03787 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
FHJKHKDH_03788 2.2e-97 K Bacterial regulatory proteins, tetR family
FHJKHKDH_03789 9e-51 S DoxX-like family
FHJKHKDH_03790 4.7e-52 yycN 2.3.1.128 K Acetyltransferase
FHJKHKDH_03791 1e-301 expZ S ABC transporter
FHJKHKDH_03792 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
FHJKHKDH_03793 4.7e-88 dinB S DinB family
FHJKHKDH_03794 1.5e-78 K helix_turn_helix multiple antibiotic resistance protein
FHJKHKDH_03795 0.0 ydgH S drug exporters of the RND superfamily
FHJKHKDH_03796 1e-113 drgA C nitroreductase
FHJKHKDH_03797 4.1e-69 ydgJ K Winged helix DNA-binding domain
FHJKHKDH_03798 6.3e-208 tcaB EGP Major facilitator Superfamily
FHJKHKDH_03799 3.5e-121 ydhB S membrane transporter protein
FHJKHKDH_03800 2.5e-121 ydhC K FCD
FHJKHKDH_03801 2.8e-243 ydhD M Glycosyl hydrolase
FHJKHKDH_03802 2.7e-227 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
FHJKHKDH_03803 1.2e-121
FHJKHKDH_03804 5.2e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
FHJKHKDH_03805 4.3e-67 frataxin S Domain of unknown function (DU1801)
FHJKHKDH_03807 4.7e-82 K Acetyltransferase (GNAT) domain
FHJKHKDH_03808 2.9e-179 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
FHJKHKDH_03809 9.4e-98 ydhK M Protein of unknown function (DUF1541)
FHJKHKDH_03810 7.9e-200 pbuE EGP Major facilitator Superfamily
FHJKHKDH_03811 1.2e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
FHJKHKDH_03812 4.3e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
FHJKHKDH_03813 2.6e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
FHJKHKDH_03814 1.2e-282 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FHJKHKDH_03815 1.3e-131 ydhQ K UTRA
FHJKHKDH_03816 6.2e-168 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
FHJKHKDH_03817 2.8e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
FHJKHKDH_03818 9.9e-213 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
FHJKHKDH_03819 6.1e-157 ydhU P Catalase
FHJKHKDH_03822 1.5e-245 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
FHJKHKDH_03823 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
FHJKHKDH_03824 4.7e-137 ybbA S Putative esterase
FHJKHKDH_03825 5.6e-178 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FHJKHKDH_03826 3.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FHJKHKDH_03827 1.4e-165 feuA P Iron-uptake system-binding protein
FHJKHKDH_03828 2.5e-305 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
FHJKHKDH_03829 2.7e-238 ybbC 3.2.1.52 S protein conserved in bacteria
FHJKHKDH_03830 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
FHJKHKDH_03831 3.1e-253 yfeW 3.4.16.4 V Belongs to the UPF0214 family
FHJKHKDH_03832 1.3e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
FHJKHKDH_03833 2.3e-148 ybbH K transcriptional
FHJKHKDH_03834 8.8e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FHJKHKDH_03835 7.1e-86 ybbJ J acetyltransferase
FHJKHKDH_03836 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
FHJKHKDH_03842 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
FHJKHKDH_03843 6.3e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
FHJKHKDH_03844 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FHJKHKDH_03845 1.5e-224 ybbR S protein conserved in bacteria
FHJKHKDH_03846 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FHJKHKDH_03847 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
FHJKHKDH_03848 1e-170 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FHJKHKDH_03849 3.2e-118 adaA 3.2.2.21 K Transcriptional regulator
FHJKHKDH_03850 9.6e-100 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FHJKHKDH_03851 8.8e-276 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
FHJKHKDH_03852 0.0 ybcC S Belongs to the UPF0753 family
FHJKHKDH_03853 3.6e-91 can 4.2.1.1 P carbonic anhydrase
FHJKHKDH_03854 8.7e-47
FHJKHKDH_03855 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
FHJKHKDH_03857 5.1e-50 ybzH K Helix-turn-helix domain
FHJKHKDH_03858 7.2e-201 ybcL EGP Major facilitator Superfamily
FHJKHKDH_03860 2.8e-33 O Subtilase family
FHJKHKDH_03861 2.5e-123 spaB S Lantibiotic dehydratase, C terminus
FHJKHKDH_03862 3.7e-60 spaC1 V Lanthionine synthetase C-like protein
FHJKHKDH_03864 1.4e-144 msbA2 3.6.3.44 V ABC transporter
FHJKHKDH_03865 1.4e-181 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
FHJKHKDH_03866 4.2e-121 T Transcriptional regulatory protein, C terminal
FHJKHKDH_03867 2.2e-171 T His Kinase A (phospho-acceptor) domain
FHJKHKDH_03869 3.7e-137 KLT Protein tyrosine kinase
FHJKHKDH_03870 3.8e-151 ybdN
FHJKHKDH_03871 2.2e-213 ybdO S Domain of unknown function (DUF4885)
FHJKHKDH_03872 5.8e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
FHJKHKDH_03873 1.1e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
FHJKHKDH_03874 4.9e-30 ybxH S Family of unknown function (DUF5370)
FHJKHKDH_03875 3e-150 ybxI 3.5.2.6 V beta-lactamase
FHJKHKDH_03876 4.3e-244 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
FHJKHKDH_03877 4.9e-41 ybyB
FHJKHKDH_03878 1.1e-289 ybeC E amino acid
FHJKHKDH_03879 5.3e-164 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
FHJKHKDH_03880 7.3e-258 glpT G -transporter
FHJKHKDH_03881 8.5e-35 S Protein of unknown function (DUF2651)
FHJKHKDH_03882 1.4e-170 ybfA 3.4.15.5 K FR47-like protein
FHJKHKDH_03883 1.9e-223 ybfB G COG0477 Permeases of the major facilitator superfamily
FHJKHKDH_03885 0.0 ybfG M Domain of unknown function (DUF1906)
FHJKHKDH_03886 8.8e-162 ybfH EG EamA-like transporter family
FHJKHKDH_03887 2.3e-145 msmR K AraC-like ligand binding domain
FHJKHKDH_03888 1.9e-214 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FHJKHKDH_03889 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
FHJKHKDH_03891 2.5e-169 S Alpha/beta hydrolase family
FHJKHKDH_03892 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FHJKHKDH_03893 2.7e-85 ybfM S SNARE associated Golgi protein
FHJKHKDH_03894 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
FHJKHKDH_03895 4.6e-45 ybfN
FHJKHKDH_03896 3.9e-192 yceA S Belongs to the UPF0176 family
FHJKHKDH_03897 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
FHJKHKDH_03898 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
FHJKHKDH_03899 3e-136 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
FHJKHKDH_03900 4.9e-128 K UTRA
FHJKHKDH_03902 2e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
FHJKHKDH_03903 5.7e-261 mmuP E amino acid
FHJKHKDH_03904 1e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
FHJKHKDH_03905 2.8e-255 agcS E Sodium alanine symporter
FHJKHKDH_03906 1.5e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
FHJKHKDH_03907 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
FHJKHKDH_03908 9e-170 glnL T Regulator
FHJKHKDH_03909 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
FHJKHKDH_03910 2.2e-271 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
FHJKHKDH_03911 2.9e-254 gudP G COG0477 Permeases of the major facilitator superfamily
FHJKHKDH_03912 9.4e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
FHJKHKDH_03913 2.5e-124 ycbG K FCD
FHJKHKDH_03914 7.7e-296 garD 4.2.1.42, 4.2.1.7 G Altronate
FHJKHKDH_03915 7e-175 ycbJ S Macrolide 2'-phosphotransferase
FHJKHKDH_03916 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
FHJKHKDH_03917 4e-170 eamA1 EG spore germination
FHJKHKDH_03918 1.9e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FHJKHKDH_03919 1.6e-166 T PhoQ Sensor
FHJKHKDH_03920 4.8e-168 ycbN V ABC transporter, ATP-binding protein
FHJKHKDH_03921 5.1e-114 S ABC-2 family transporter protein
FHJKHKDH_03922 4.1e-52 ycbP S Protein of unknown function (DUF2512)
FHJKHKDH_03923 1.3e-78 sleB 3.5.1.28 M Cell wall
FHJKHKDH_03924 9.5e-135 ycbR T vWA found in TerF C terminus
FHJKHKDH_03925 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
FHJKHKDH_03926 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
FHJKHKDH_03927 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FHJKHKDH_03928 2.2e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FHJKHKDH_03929 1.1e-203 ycbU E Selenocysteine lyase
FHJKHKDH_03930 3e-225 lmrB EGP the major facilitator superfamily
FHJKHKDH_03931 6.3e-102 yxaF K Transcriptional regulator
FHJKHKDH_03932 2.6e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
FHJKHKDH_03933 2.1e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
FHJKHKDH_03934 2e-59 S RDD family
FHJKHKDH_03935 3.6e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
FHJKHKDH_03936 4.7e-158 2.7.13.3 T GHKL domain
FHJKHKDH_03937 1.2e-126 lytR_2 T LytTr DNA-binding domain
FHJKHKDH_03938 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
FHJKHKDH_03939 2.2e-202 natB CP ABC-2 family transporter protein
FHJKHKDH_03940 1e-173 yccK C Aldo keto reductase
FHJKHKDH_03941 6.6e-177 ycdA S Domain of unknown function (DUF5105)
FHJKHKDH_03942 1.6e-271 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
FHJKHKDH_03943 3.1e-257 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
FHJKHKDH_03944 7.3e-94 cwlK M D-alanyl-D-alanine carboxypeptidase
FHJKHKDH_03945 1.2e-173 S response regulator aspartate phosphatase
FHJKHKDH_03946 1.8e-139 IQ Enoyl-(Acyl carrier protein) reductase
FHJKHKDH_03947 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
FHJKHKDH_03948 4.3e-167 adcA P Belongs to the bacterial solute-binding protein 9 family
FHJKHKDH_03949 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
FHJKHKDH_03950 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
FHJKHKDH_03951 4.2e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FHJKHKDH_03952 1.9e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
FHJKHKDH_03953 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
FHJKHKDH_03954 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
FHJKHKDH_03955 7e-136 terC P Protein of unknown function (DUF475)
FHJKHKDH_03956 0.0 yceG S Putative component of 'biosynthetic module'
FHJKHKDH_03957 2e-192 yceH P Belongs to the TelA family
FHJKHKDH_03958 1.1e-217 naiP P Uncharacterised MFS-type transporter YbfB
FHJKHKDH_03959 5.1e-207 yceJ EGP Uncharacterised MFS-type transporter YbfB
FHJKHKDH_03960 6.1e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
FHJKHKDH_03961 5.1e-229 proV 3.6.3.32 E glycine betaine
FHJKHKDH_03962 1.3e-127 opuAB P glycine betaine
FHJKHKDH_03963 1.5e-163 opuAC E glycine betaine
FHJKHKDH_03964 1.4e-217 amhX S amidohydrolase
FHJKHKDH_03965 5.6e-256 ycgA S Membrane
FHJKHKDH_03966 4.1e-81 ycgB
FHJKHKDH_03967 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
FHJKHKDH_03968 6.2e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
FHJKHKDH_03969 3e-290 lctP C L-lactate permease
FHJKHKDH_03970 1.4e-260 mdr EGP Major facilitator Superfamily
FHJKHKDH_03971 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
FHJKHKDH_03972 6.8e-113 ycgF E Lysine exporter protein LysE YggA
FHJKHKDH_03973 1.4e-149 yqcI S YqcI/YcgG family
FHJKHKDH_03974 6.2e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
FHJKHKDH_03975 2.4e-112 ycgI S Domain of unknown function (DUF1989)
FHJKHKDH_03976 4.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
FHJKHKDH_03977 1e-41 tmrB S AAA domain
FHJKHKDH_03978 7.5e-17 tmrB S AAA domain
FHJKHKDH_03980 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FHJKHKDH_03981 4.4e-143 yafE Q ubiE/COQ5 methyltransferase family
FHJKHKDH_03982 6.7e-176 oxyR3 K LysR substrate binding domain
FHJKHKDH_03983 2.7e-182 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
FHJKHKDH_03984 7.8e-143 ycgL S Predicted nucleotidyltransferase
FHJKHKDH_03985 5.1e-170 ycgM E Proline dehydrogenase
FHJKHKDH_03986 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
FHJKHKDH_03987 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FHJKHKDH_03988 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
FHJKHKDH_03989 1.3e-146 ycgQ S membrane
FHJKHKDH_03990 1.5e-137 ycgR S permeases
FHJKHKDH_03991 1.8e-156 I alpha/beta hydrolase fold
FHJKHKDH_03992 1.8e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
FHJKHKDH_03993 7.9e-274 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
FHJKHKDH_03994 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
FHJKHKDH_03995 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FHJKHKDH_03996 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FHJKHKDH_03997 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
FHJKHKDH_03998 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
FHJKHKDH_03999 2.4e-167 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
FHJKHKDH_04000 2.7e-108 yciB M ErfK YbiS YcfS YnhG
FHJKHKDH_04001 1e-226 yciC S GTPases (G3E family)
FHJKHKDH_04002 2.5e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
FHJKHKDH_04003 9.9e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
FHJKHKDH_04006 1.4e-72 yckC S membrane
FHJKHKDH_04007 7.8e-52 yckD S Protein of unknown function (DUF2680)
FHJKHKDH_04008 2.7e-287 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FHJKHKDH_04009 6.5e-69 nin S Competence protein J (ComJ)
FHJKHKDH_04010 3e-70 nucA M Deoxyribonuclease NucA/NucB
FHJKHKDH_04011 3.9e-187 tlpC 2.7.13.3 NT chemotaxis protein
FHJKHKDH_04012 1.8e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
FHJKHKDH_04013 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
FHJKHKDH_04014 1.3e-63 hxlR K transcriptional
FHJKHKDH_04015 3.7e-77 S N-acetylmuramoyl-L-alanine amidase activity
FHJKHKDH_04016 6.7e-12
FHJKHKDH_04019 1.5e-09 S SPP1 phage holin
FHJKHKDH_04020 3.4e-106 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 CBM50 M Glycosyl hydrolases family 25
FHJKHKDH_04021 5.6e-98 S Phage integrase family
FHJKHKDH_04022 4.6e-174 A Pre-toxin TG
FHJKHKDH_04023 6.6e-64 S Immunity protein 70
FHJKHKDH_04025 7.8e-61
FHJKHKDH_04026 1.1e-120
FHJKHKDH_04028 5.4e-13 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
FHJKHKDH_04034 3.4e-57 traC L Domain of unknown function (DUF1738)
FHJKHKDH_04035 1.2e-147 S DNA gyrase/topoisomerase IV, subunit A
FHJKHKDH_04036 2.6e-184 S DNA gyrase B
FHJKHKDH_04037 4e-15 repA S Replication initiator protein A (RepA) N-terminus
FHJKHKDH_04039 3.4e-10 tdk 2.7.1.21 F Psort location Cytoplasmic, score
FHJKHKDH_04045 5.6e-18 S Endodeoxyribonuclease RusA
FHJKHKDH_04046 6.3e-22 2.7.4.8 F Guanylate kinase homologues.
FHJKHKDH_04050 0.0 S Bacterial DNA polymerase III alpha subunit
FHJKHKDH_04052 4.4e-10 thyX 2.1.1.148 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
FHJKHKDH_04054 1.8e-46 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FHJKHKDH_04058 7.6e-07 yfbR S HD containing hydrolase-like enzyme
FHJKHKDH_04060 6.6e-17 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
FHJKHKDH_04061 5.1e-13 K Transcriptional regulator
FHJKHKDH_04062 8e-87 S exonuclease activity
FHJKHKDH_04064 1.9e-91 S DNA primase activity
FHJKHKDH_04065 4.7e-110 S DNA helicase activity
FHJKHKDH_04066 2.1e-16
FHJKHKDH_04067 1.3e-34
FHJKHKDH_04069 1e-39
FHJKHKDH_04071 1.2e-10 fld C flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
FHJKHKDH_04072 1.2e-103 S Ribonucleotide reductase, small chain
FHJKHKDH_04073 9.5e-277 S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
FHJKHKDH_04074 1.9e-64 S AAA domain
FHJKHKDH_04077 1.1e-47 F Nucleoside 2-deoxyribosyltransferase
FHJKHKDH_04078 5.1e-35
FHJKHKDH_04080 1.1e-38
FHJKHKDH_04081 2.3e-32 yxcD S Protein of unknown function (DUF2653)
FHJKHKDH_04083 8.1e-20
FHJKHKDH_04084 1.2e-41 XK27_03185 S Phosphoribosyl-ATP pyrophosphohydrolase
FHJKHKDH_04087 6.4e-52
FHJKHKDH_04088 1.3e-69 L Phage integrase family
FHJKHKDH_04091 1.6e-22 yocH 3.5.1.28 M 3D domain
FHJKHKDH_04092 4.6e-68 lig 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP dependent DNA ligase domain
FHJKHKDH_04094 9.7e-83
FHJKHKDH_04096 5e-178 S response regulator aspartate phosphatase
FHJKHKDH_04099 9.5e-30 S Phage terminase, small subunit
FHJKHKDH_04102 1.2e-106 S Phage portal protein
FHJKHKDH_04103 3.9e-56 S Caudovirus prohead serine protease
FHJKHKDH_04104 6.8e-87 S Phage capsid family
FHJKHKDH_04106 1.4e-21 S DNA packaging
FHJKHKDH_04107 1.8e-11 S Phage head-tail joining protein
FHJKHKDH_04108 7.4e-14 S Bacteriophage HK97-gp10, putative tail-component
FHJKHKDH_04109 1.9e-07
FHJKHKDH_04110 1.6e-40 S Phage tail tube protein
FHJKHKDH_04112 3.2e-173 D Phage tail tape measure protein
FHJKHKDH_04113 2.3e-176 S Phage tail protein
FHJKHKDH_04114 1.8e-147 S Phage minor structural protein
FHJKHKDH_04115 4e-23
FHJKHKDH_04118 1.1e-77 S Protein of unknown function DUF262
FHJKHKDH_04119 1.6e-07 abrB K Transcriptional regulator, AbrB family
FHJKHKDH_04120 3.5e-24
FHJKHKDH_04121 4.9e-36
FHJKHKDH_04124 6.2e-79 M Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
FHJKHKDH_04125 7.6e-176 traE U Psort location Cytoplasmic, score
FHJKHKDH_04126 1.5e-64
FHJKHKDH_04128 1.3e-20 S Helix-turn-helix domain
FHJKHKDH_04130 8.7e-106
FHJKHKDH_04133 6.3e-12
FHJKHKDH_04135 1.2e-78 traA L MobA MobL family protein
FHJKHKDH_04136 2.8e-116 traK U COG3505 Type IV secretory pathway, VirD4 components
FHJKHKDH_04137 1.2e-193 traI 5.99.1.2 L DNA topoisomerase III
FHJKHKDH_04140 3e-70 E Zn peptidase
FHJKHKDH_04154 5.2e-15 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
FHJKHKDH_04156 2.8e-17 D plasmid maintenance
FHJKHKDH_04158 1.7e-26 srtA 3.4.22.70 M Cysteine protease
FHJKHKDH_04161 4.4e-78 N Pkd domain containing protein
FHJKHKDH_04163 3.5e-29 cpaB U Flp pilus assembly protein RcpC/CpaB
FHJKHKDH_04164 1.8e-20 D bacterial-type flagellum organization
FHJKHKDH_04165 2e-35 U COG4962 Flp pilus assembly protein, ATPase CpaF
FHJKHKDH_04173 3.4e-24 V VanZ like family
FHJKHKDH_04182 9.5e-100 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
FHJKHKDH_04183 2.6e-72
FHJKHKDH_04185 2.9e-126 J tRNA cytidylyltransferase activity
FHJKHKDH_04186 2.8e-45
FHJKHKDH_04187 2.1e-13
FHJKHKDH_04192 3.9e-68 L Resolvase, N terminal domain
FHJKHKDH_04195 1.9e-23
FHJKHKDH_04196 6.7e-10
FHJKHKDH_04201 1.3e-39 yjqA S Bacterial PH domain
FHJKHKDH_04202 2.7e-38 V HNH endonuclease
FHJKHKDH_04205 8.1e-24
FHJKHKDH_04215 1.8e-34 V HNH endonuclease
FHJKHKDH_04220 2.4e-71 S response regulator aspartate phosphatase
FHJKHKDH_04222 1.5e-20
FHJKHKDH_04227 2.9e-76 ctsR K Belongs to the CtsR family
FHJKHKDH_04228 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
FHJKHKDH_04229 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
FHJKHKDH_04230 0.0 clpC O Belongs to the ClpA ClpB family
FHJKHKDH_04231 6.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FHJKHKDH_04232 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FHJKHKDH_04233 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
FHJKHKDH_04234 7.2e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
FHJKHKDH_04235 1.2e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
FHJKHKDH_04236 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FHJKHKDH_04237 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
FHJKHKDH_04238 9.3e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
FHJKHKDH_04239 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FHJKHKDH_04240 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FHJKHKDH_04241 1.2e-88 yacP S RNA-binding protein containing a PIN domain
FHJKHKDH_04242 4.4e-115 sigH K Belongs to the sigma-70 factor family
FHJKHKDH_04243 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
FHJKHKDH_04244 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
FHJKHKDH_04245 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FHJKHKDH_04246 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
FHJKHKDH_04247 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FHJKHKDH_04248 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
FHJKHKDH_04249 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
FHJKHKDH_04250 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FHJKHKDH_04251 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FHJKHKDH_04252 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
FHJKHKDH_04253 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FHJKHKDH_04254 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
FHJKHKDH_04255 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FHJKHKDH_04256 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FHJKHKDH_04257 8.2e-179 ybaC 3.4.11.5 S Alpha/beta hydrolase family
FHJKHKDH_04258 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
FHJKHKDH_04259 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FHJKHKDH_04260 3e-105 rplD J Forms part of the polypeptide exit tunnel
FHJKHKDH_04261 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
FHJKHKDH_04262 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FHJKHKDH_04263 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FHJKHKDH_04264 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FHJKHKDH_04265 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FHJKHKDH_04266 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FHJKHKDH_04267 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
FHJKHKDH_04268 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FHJKHKDH_04269 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FHJKHKDH_04270 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FHJKHKDH_04271 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FHJKHKDH_04272 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FHJKHKDH_04273 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FHJKHKDH_04274 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FHJKHKDH_04275 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FHJKHKDH_04276 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FHJKHKDH_04277 1.9e-23 rpmD J Ribosomal protein L30
FHJKHKDH_04278 1.8e-72 rplO J binds to the 23S rRNA
FHJKHKDH_04279 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
FHJKHKDH_04280 4.8e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
FHJKHKDH_04281 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
FHJKHKDH_04282 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FHJKHKDH_04283 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
FHJKHKDH_04284 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FHJKHKDH_04285 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FHJKHKDH_04286 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FHJKHKDH_04287 3.6e-58 rplQ J Ribosomal protein L17
FHJKHKDH_04288 1.5e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FHJKHKDH_04289 2.4e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FHJKHKDH_04290 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FHJKHKDH_04291 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
FHJKHKDH_04292 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FHJKHKDH_04293 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
FHJKHKDH_04294 8.2e-145 ybaJ Q Methyltransferase domain
FHJKHKDH_04295 9.7e-66 ybaK S Protein of unknown function (DUF2521)
FHJKHKDH_04296 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
FHJKHKDH_04297 3e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
FHJKHKDH_04298 1.2e-84 gerD
FHJKHKDH_04299 3.9e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
FHJKHKDH_04300 4.6e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
FHJKHKDH_04301 8.4e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
FHJKHKDH_04302 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FHJKHKDH_04303 4.1e-30 yazB K transcriptional
FHJKHKDH_04304 6e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FHJKHKDH_04305 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FHJKHKDH_04306 8.5e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FHJKHKDH_04307 2.3e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
FHJKHKDH_04308 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
FHJKHKDH_04309 3.7e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FHJKHKDH_04310 1.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
FHJKHKDH_04311 3.4e-152 yacD 5.2.1.8 O peptidyl-prolyl isomerase
FHJKHKDH_04312 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FHJKHKDH_04313 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FHJKHKDH_04314 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FHJKHKDH_04315 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
FHJKHKDH_04316 1.2e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
FHJKHKDH_04317 4.1e-184 KLT serine threonine protein kinase
FHJKHKDH_04318 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
FHJKHKDH_04319 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
FHJKHKDH_04322 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
FHJKHKDH_04323 1.1e-44 divIC D Septum formation initiator
FHJKHKDH_04324 3.9e-108 yabQ S spore cortex biosynthesis protein
FHJKHKDH_04325 1.5e-49 yabP S Sporulation protein YabP
FHJKHKDH_04326 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
FHJKHKDH_04327 2.7e-245 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
FHJKHKDH_04328 2.4e-287 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
FHJKHKDH_04329 1.5e-92 spoVT K stage V sporulation protein
FHJKHKDH_04330 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FHJKHKDH_04331 2.4e-39 yabK S Peptide ABC transporter permease
FHJKHKDH_04332 1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
FHJKHKDH_04333 9.6e-96 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FHJKHKDH_04334 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FHJKHKDH_04335 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FHJKHKDH_04336 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
FHJKHKDH_04337 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
FHJKHKDH_04338 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
FHJKHKDH_04339 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FHJKHKDH_04340 8.3e-27 sspF S DNA topological change
FHJKHKDH_04341 7.8e-39 veg S protein conserved in bacteria
FHJKHKDH_04342 1.8e-135 yabG S peptidase
FHJKHKDH_04343 4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
FHJKHKDH_04344 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FHJKHKDH_04345 5.8e-167 rpfB GH23 T protein conserved in bacteria
FHJKHKDH_04346 4.5e-143 tatD L hydrolase, TatD
FHJKHKDH_04347 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FHJKHKDH_04348 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
FHJKHKDH_04349 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FHJKHKDH_04350 1.5e-49 yazA L endonuclease containing a URI domain
FHJKHKDH_04351 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
FHJKHKDH_04352 4.8e-31 yabA L Involved in initiation control of chromosome replication
FHJKHKDH_04353 2.1e-146 yaaT S stage 0 sporulation protein
FHJKHKDH_04354 2.2e-182 holB 2.7.7.7 L DNA polymerase III
FHJKHKDH_04355 1.5e-71 yaaR S protein conserved in bacteria
FHJKHKDH_04356 2.2e-54 yaaQ S protein conserved in bacteria
FHJKHKDH_04357 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FHJKHKDH_04358 1e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
FHJKHKDH_04359 2.9e-202 yaaN P Belongs to the TelA family
FHJKHKDH_04360 4.7e-103 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
FHJKHKDH_04361 3.4e-31 csfB S Inhibitor of sigma-G Gin
FHJKHKDH_04362 1.8e-35 bofA S Sigma-K factor-processing regulatory protein BofA
FHJKHKDH_04363 7.9e-32 yaaL S Protein of unknown function (DUF2508)
FHJKHKDH_04364 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FHJKHKDH_04365 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FHJKHKDH_04366 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FHJKHKDH_04367 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
FHJKHKDH_04368 5.5e-95 yaaI Q COG1335 Amidases related to nicotinamidase
FHJKHKDH_04369 1.5e-212 yaaH M Glycoside Hydrolase Family
FHJKHKDH_04370 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
FHJKHKDH_04371 8.3e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
FHJKHKDH_04372 1.3e-09
FHJKHKDH_04373 3.1e-205 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FHJKHKDH_04374 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FHJKHKDH_04375 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FHJKHKDH_04376 6.8e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
FHJKHKDH_04377 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
FHJKHKDH_04378 8.7e-181 yaaC S YaaC-like Protein
FHJKHKDH_04379 2.5e-250 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FHJKHKDH_04380 4e-92 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FHJKHKDH_04381 1.3e-177 L Replication protein
FHJKHKDH_04383 4.2e-25 traI 2.5.1.15 U relaxase mobilization nuclease domain protein
FHJKHKDH_04386 3.4e-39 S COG NOG14552 non supervised orthologous group
FHJKHKDH_04390 2e-08
FHJKHKDH_04397 7.8e-08
FHJKHKDH_04400 1.4e-68 dld 1.1.5.12 C Catalyzes the oxidation of D-lactate to pyruvate
FHJKHKDH_04404 2e-08

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)