ORF_ID e_value Gene_name EC_number CAZy COGs Description
DOFFALOB_00005 2e-08
DOFFALOB_00012 1.3e-09
DOFFALOB_00013 7.8e-08
DOFFALOB_00022 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DOFFALOB_00023 3.6e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DOFFALOB_00024 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
DOFFALOB_00025 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
DOFFALOB_00026 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
DOFFALOB_00027 9.9e-77 tspO T membrane
DOFFALOB_00028 1.8e-206 cotI S Spore coat protein
DOFFALOB_00029 1.8e-217 cotSA M Glycosyl transferases group 1
DOFFALOB_00030 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
DOFFALOB_00032 3.6e-235 ytcC M Glycosyltransferase Family 4
DOFFALOB_00033 3.9e-181 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
DOFFALOB_00034 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DOFFALOB_00035 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
DOFFALOB_00036 2.6e-132 dksA T COG1734 DnaK suppressor protein
DOFFALOB_00037 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
DOFFALOB_00038 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DOFFALOB_00039 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
DOFFALOB_00040 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DOFFALOB_00041 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
DOFFALOB_00042 1.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
DOFFALOB_00043 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
DOFFALOB_00044 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
DOFFALOB_00045 3.2e-234 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
DOFFALOB_00046 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
DOFFALOB_00047 1.1e-24 S Domain of Unknown Function (DUF1540)
DOFFALOB_00048 7.3e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
DOFFALOB_00049 4.7e-249 cydA 1.10.3.14 C oxidase, subunit
DOFFALOB_00050 3.6e-41 rpmE2 J Ribosomal protein L31
DOFFALOB_00051 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
DOFFALOB_00052 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DOFFALOB_00053 3.6e-73 ytkA S YtkA-like
DOFFALOB_00055 2.1e-76 dps P Belongs to the Dps family
DOFFALOB_00056 5.4e-63 ytkC S Bacteriophage holin family
DOFFALOB_00057 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
DOFFALOB_00058 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
DOFFALOB_00059 1.4e-144 ytlC P ABC transporter
DOFFALOB_00060 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
DOFFALOB_00061 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
DOFFALOB_00062 1.2e-38 ytmB S Protein of unknown function (DUF2584)
DOFFALOB_00063 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
DOFFALOB_00064 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DOFFALOB_00065 0.0 asnB 6.3.5.4 E Asparagine synthase
DOFFALOB_00066 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
DOFFALOB_00067 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DOFFALOB_00068 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
DOFFALOB_00069 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
DOFFALOB_00070 3.3e-106 ytqB J Putative rRNA methylase
DOFFALOB_00071 2.1e-190 yhcC S Fe-S oxidoreductase
DOFFALOB_00072 6.7e-41 ytzC S Protein of unknown function (DUF2524)
DOFFALOB_00074 5.1e-66 ytrA K GntR family transcriptional regulator
DOFFALOB_00075 1.1e-161 ytrB P abc transporter atp-binding protein
DOFFALOB_00076 6.1e-169 P ABC-2 family transporter protein
DOFFALOB_00077 5.9e-148
DOFFALOB_00078 3.1e-127 ytrE V ABC transporter, ATP-binding protein
DOFFALOB_00079 8.5e-235 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
DOFFALOB_00080 5.2e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DOFFALOB_00081 5.6e-186 T PhoQ Sensor
DOFFALOB_00082 1.1e-138 bceA V ABC transporter, ATP-binding protein
DOFFALOB_00083 0.0 bceB V ABC transporter (permease)
DOFFALOB_00084 1.8e-43 yttA 2.7.13.3 S Pfam Transposase IS66
DOFFALOB_00085 2.1e-211 yttB EGP Major facilitator Superfamily
DOFFALOB_00086 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
DOFFALOB_00087 7.7e-55 ytvB S Protein of unknown function (DUF4257)
DOFFALOB_00088 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
DOFFALOB_00089 2.1e-51 ytwF P Sulfurtransferase
DOFFALOB_00090 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
DOFFALOB_00091 1.5e-144 amyC P ABC transporter (permease)
DOFFALOB_00092 3.7e-168 amyD P ABC transporter
DOFFALOB_00093 2.3e-248 msmE G Bacterial extracellular solute-binding protein
DOFFALOB_00094 2.3e-190 msmR K Transcriptional regulator
DOFFALOB_00095 1.3e-173 ytaP S Acetyl xylan esterase (AXE1)
DOFFALOB_00096 1.6e-142 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
DOFFALOB_00097 2.4e-261 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
DOFFALOB_00098 1.4e-220 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
DOFFALOB_00099 3.7e-128 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DOFFALOB_00100 2.2e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DOFFALOB_00101 1.9e-225 bioI 1.14.14.46 C Cytochrome P450
DOFFALOB_00102 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
DOFFALOB_00103 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
DOFFALOB_00104 1.2e-290 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
DOFFALOB_00105 0.0 ytdP K Transcriptional regulator
DOFFALOB_00106 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
DOFFALOB_00107 4.7e-226 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
DOFFALOB_00108 4.6e-73 yteS G transport
DOFFALOB_00109 2.6e-249 yteT S Oxidoreductase family, C-terminal alpha/beta domain
DOFFALOB_00110 4.8e-117 yteU S Integral membrane protein
DOFFALOB_00111 3.1e-26 yteV S Sporulation protein Cse60
DOFFALOB_00112 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
DOFFALOB_00113 8.2e-232 ytfP S HI0933-like protein
DOFFALOB_00114 1.9e-281 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
DOFFALOB_00115 2.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DOFFALOB_00116 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
DOFFALOB_00117 4.3e-132 ythP V ABC transporter
DOFFALOB_00118 3.9e-207 ythQ U Bacterial ABC transporter protein EcsB
DOFFALOB_00119 7.2e-226 pbuO S permease
DOFFALOB_00120 7.1e-272 pepV 3.5.1.18 E Dipeptidase
DOFFALOB_00121 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
DOFFALOB_00122 4.3e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DOFFALOB_00123 1.3e-165 ytlQ
DOFFALOB_00124 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
DOFFALOB_00125 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
DOFFALOB_00126 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
DOFFALOB_00127 2e-45 ytzH S YtzH-like protein
DOFFALOB_00128 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DOFFALOB_00129 6.4e-151 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
DOFFALOB_00130 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
DOFFALOB_00131 9.8e-52 ytzB S small secreted protein
DOFFALOB_00132 4.7e-207 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
DOFFALOB_00133 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
DOFFALOB_00134 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
DOFFALOB_00135 9.8e-149 ytpQ S Belongs to the UPF0354 family
DOFFALOB_00136 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DOFFALOB_00137 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
DOFFALOB_00138 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
DOFFALOB_00139 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DOFFALOB_00140 6.6e-17 ytxH S COG4980 Gas vesicle protein
DOFFALOB_00141 4.4e-55 ytxJ O Protein of unknown function (DUF2847)
DOFFALOB_00142 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
DOFFALOB_00143 1.7e-182 ccpA K catabolite control protein A
DOFFALOB_00144 7.1e-147 motA N flagellar motor
DOFFALOB_00145 1.4e-125 motS N Flagellar motor protein
DOFFALOB_00146 1.9e-225 acuC BQ histone deacetylase
DOFFALOB_00147 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
DOFFALOB_00148 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
DOFFALOB_00149 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
DOFFALOB_00150 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DOFFALOB_00152 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DOFFALOB_00153 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
DOFFALOB_00154 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
DOFFALOB_00155 3.4e-109 yttP K Transcriptional regulator
DOFFALOB_00156 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
DOFFALOB_00157 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DOFFALOB_00158 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
DOFFALOB_00159 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
DOFFALOB_00160 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DOFFALOB_00161 2e-29 sspB S spore protein
DOFFALOB_00162 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
DOFFALOB_00163 0.0 ytcJ S amidohydrolase
DOFFALOB_00164 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DOFFALOB_00165 2.4e-181 sppA OU signal peptide peptidase SppA
DOFFALOB_00166 1.3e-87 yteJ S RDD family
DOFFALOB_00167 5.6e-116 ytfI S Protein of unknown function (DUF2953)
DOFFALOB_00168 8.7e-70 ytfJ S Sporulation protein YtfJ
DOFFALOB_00169 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DOFFALOB_00170 7e-165 ytxK 2.1.1.72 L DNA methylase
DOFFALOB_00171 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DOFFALOB_00172 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
DOFFALOB_00173 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
DOFFALOB_00174 3.1e-267 argH 4.3.2.1 E argininosuccinate lyase
DOFFALOB_00176 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DOFFALOB_00177 1.7e-130 ytkL S Belongs to the UPF0173 family
DOFFALOB_00178 2.9e-173 ytlI K LysR substrate binding domain
DOFFALOB_00179 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
DOFFALOB_00180 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
DOFFALOB_00181 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
DOFFALOB_00182 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
DOFFALOB_00183 7.6e-121 tcyM U Binding-protein-dependent transport system inner membrane component
DOFFALOB_00184 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
DOFFALOB_00185 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DOFFALOB_00186 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
DOFFALOB_00187 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DOFFALOB_00188 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
DOFFALOB_00189 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
DOFFALOB_00190 1.2e-158 ytnM S membrane transporter protein
DOFFALOB_00191 8e-241 ytoI K transcriptional regulator containing CBS domains
DOFFALOB_00192 2.4e-47 ytpI S YtpI-like protein
DOFFALOB_00193 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
DOFFALOB_00194 9.2e-29
DOFFALOB_00195 8.2e-69 ytrI
DOFFALOB_00196 3.2e-56 ytrH S Sporulation protein YtrH
DOFFALOB_00197 0.0 dnaE 2.7.7.7 L DNA polymerase
DOFFALOB_00198 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
DOFFALOB_00199 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DOFFALOB_00200 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
DOFFALOB_00201 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
DOFFALOB_00202 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
DOFFALOB_00203 1.8e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
DOFFALOB_00204 2.6e-192 ytvI S sporulation integral membrane protein YtvI
DOFFALOB_00205 4.7e-71 yeaL S membrane
DOFFALOB_00206 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
DOFFALOB_00207 1.8e-242 icd 1.1.1.42 C isocitrate
DOFFALOB_00208 1.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
DOFFALOB_00209 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DOFFALOB_00210 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
DOFFALOB_00211 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DOFFALOB_00212 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
DOFFALOB_00213 1.1e-107 ytaF P Probably functions as a manganese efflux pump
DOFFALOB_00214 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DOFFALOB_00215 8.9e-161 ytbE S reductase
DOFFALOB_00216 4.9e-205 ytbD EGP Major facilitator Superfamily
DOFFALOB_00217 9.9e-67 ytcD K Transcriptional regulator
DOFFALOB_00218 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DOFFALOB_00219 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DOFFALOB_00220 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DOFFALOB_00221 3.5e-266 dnaB L Membrane attachment protein
DOFFALOB_00222 3e-173 dnaI L Primosomal protein DnaI
DOFFALOB_00223 4.9e-111 ytxB S SNARE associated Golgi protein
DOFFALOB_00224 3.8e-159 ytxC S YtxC-like family
DOFFALOB_00225 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DOFFALOB_00226 1.5e-149 ysaA S HAD-hyrolase-like
DOFFALOB_00227 0.0 lytS 2.7.13.3 T Histidine kinase
DOFFALOB_00228 6.3e-131 lytT T COG3279 Response regulator of the LytR AlgR family
DOFFALOB_00229 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
DOFFALOB_00230 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
DOFFALOB_00232 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DOFFALOB_00233 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
DOFFALOB_00234 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DOFFALOB_00235 7.5e-45 ysdA S Membrane
DOFFALOB_00236 9.2e-68 ysdB S Sigma-w pathway protein YsdB
DOFFALOB_00237 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
DOFFALOB_00238 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
DOFFALOB_00239 1.9e-294 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
DOFFALOB_00240 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
DOFFALOB_00241 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
DOFFALOB_00242 4.1e-147 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
DOFFALOB_00243 5e-226 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
DOFFALOB_00244 2.8e-254 araN G carbohydrate transport
DOFFALOB_00245 1.4e-167 araP G carbohydrate transport
DOFFALOB_00246 3.4e-144 araQ G transport system permease
DOFFALOB_00247 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
DOFFALOB_00248 0.0 cstA T Carbon starvation protein
DOFFALOB_00250 3.6e-38 ysfE 4.4.1.5 E lactoylglutathione lyase activity
DOFFALOB_00251 5.6e-258 glcF C Glycolate oxidase
DOFFALOB_00252 7.2e-264 glcD 1.1.3.15 C Glycolate oxidase subunit
DOFFALOB_00253 4.4e-208 ysfB KT regulator
DOFFALOB_00254 2.6e-32 sspI S Belongs to the SspI family
DOFFALOB_00255 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DOFFALOB_00256 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DOFFALOB_00257 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DOFFALOB_00258 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DOFFALOB_00259 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DOFFALOB_00260 1.3e-85 cvpA S membrane protein, required for colicin V production
DOFFALOB_00261 0.0 polX L COG1796 DNA polymerase IV (family X)
DOFFALOB_00262 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
DOFFALOB_00263 7.3e-68 yshE S membrane
DOFFALOB_00264 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
DOFFALOB_00265 2.7e-100 fadR K Transcriptional regulator
DOFFALOB_00266 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
DOFFALOB_00267 4.5e-135 etfB C Electron transfer flavoprotein
DOFFALOB_00268 2.1e-177 etfA C Electron transfer flavoprotein
DOFFALOB_00270 5.7e-304 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
DOFFALOB_00271 2e-52 trxA O Belongs to the thioredoxin family
DOFFALOB_00272 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DOFFALOB_00273 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
DOFFALOB_00274 1.2e-79 yslB S Protein of unknown function (DUF2507)
DOFFALOB_00275 2.4e-107 sdhC C succinate dehydrogenase
DOFFALOB_00276 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
DOFFALOB_00277 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
DOFFALOB_00278 1.6e-76 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
DOFFALOB_00279 3.3e-30 gerE K Transcriptional regulator
DOFFALOB_00280 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
DOFFALOB_00281 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
DOFFALOB_00282 2.9e-196 gerM S COG5401 Spore germination protein
DOFFALOB_00283 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DOFFALOB_00284 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DOFFALOB_00285 1.4e-92 ysnB S Phosphoesterase
DOFFALOB_00287 9.1e-134 ysnF S protein conserved in bacteria
DOFFALOB_00288 7.6e-82 ysnE K acetyltransferase
DOFFALOB_00290 0.0 ilvB 2.2.1.6 E Acetolactate synthase
DOFFALOB_00291 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
DOFFALOB_00292 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DOFFALOB_00293 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DOFFALOB_00294 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
DOFFALOB_00295 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DOFFALOB_00296 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DOFFALOB_00297 2.3e-187 ysoA H Tetratricopeptide repeat
DOFFALOB_00298 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DOFFALOB_00299 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DOFFALOB_00300 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
DOFFALOB_00301 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DOFFALOB_00302 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
DOFFALOB_00303 1.4e-89 ysxD
DOFFALOB_00304 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DOFFALOB_00305 3.6e-146 hemX O cytochrome C
DOFFALOB_00306 3e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
DOFFALOB_00307 7.6e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
DOFFALOB_00308 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
DOFFALOB_00309 4.6e-249 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
DOFFALOB_00310 1.9e-226 spoVID M stage VI sporulation protein D
DOFFALOB_00311 1.6e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DOFFALOB_00312 1.6e-25
DOFFALOB_00313 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DOFFALOB_00314 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
DOFFALOB_00315 6.6e-85 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
DOFFALOB_00316 1.1e-168 spoIIB S Sporulation related domain
DOFFALOB_00317 2.8e-102 maf D septum formation protein Maf
DOFFALOB_00318 5.9e-126 radC E Belongs to the UPF0758 family
DOFFALOB_00319 1.8e-184 mreB D Rod shape-determining protein MreB
DOFFALOB_00320 2.8e-157 mreC M Involved in formation and maintenance of cell shape
DOFFALOB_00321 1.4e-84 mreD M shape-determining protein
DOFFALOB_00322 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
DOFFALOB_00323 2.5e-144 minD D Belongs to the ParA family
DOFFALOB_00324 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
DOFFALOB_00325 9.2e-161 spoIVFB S Stage IV sporulation protein
DOFFALOB_00326 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
DOFFALOB_00327 4.1e-56 ysxB J ribosomal protein
DOFFALOB_00328 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
DOFFALOB_00329 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
DOFFALOB_00330 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DOFFALOB_00331 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
DOFFALOB_00332 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
DOFFALOB_00333 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
DOFFALOB_00334 1.2e-230 nifS 2.8.1.7 E Cysteine desulfurase
DOFFALOB_00335 2.7e-307 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
DOFFALOB_00336 5.4e-161 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
DOFFALOB_00337 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DOFFALOB_00338 9.8e-158 safA M spore coat assembly protein SafA
DOFFALOB_00339 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
DOFFALOB_00340 1.9e-127 yebC K transcriptional regulatory protein
DOFFALOB_00341 1.8e-262 alsT E Sodium alanine symporter
DOFFALOB_00342 2.6e-35 S Family of unknown function (DUF5412)
DOFFALOB_00344 6.5e-119 yrzF T serine threonine protein kinase
DOFFALOB_00345 1.3e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
DOFFALOB_00346 5.3e-253 csbX EGP Major facilitator Superfamily
DOFFALOB_00347 4.8e-93 bofC S BofC C-terminal domain
DOFFALOB_00348 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DOFFALOB_00349 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DOFFALOB_00350 2.6e-18 yrzS S Protein of unknown function (DUF2905)
DOFFALOB_00351 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DOFFALOB_00352 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
DOFFALOB_00353 1.1e-38 yajC U Preprotein translocase subunit YajC
DOFFALOB_00354 1.2e-74 yrzE S Protein of unknown function (DUF3792)
DOFFALOB_00355 2.2e-114 yrbG S membrane
DOFFALOB_00356 5.7e-270 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
DOFFALOB_00357 9.4e-49 yrzD S Post-transcriptional regulator
DOFFALOB_00358 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DOFFALOB_00359 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
DOFFALOB_00360 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
DOFFALOB_00361 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
DOFFALOB_00362 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DOFFALOB_00363 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DOFFALOB_00364 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DOFFALOB_00365 3.9e-263 lytH 3.5.1.28 M COG3103 SH3 domain protein
DOFFALOB_00367 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
DOFFALOB_00368 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DOFFALOB_00369 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
DOFFALOB_00370 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
DOFFALOB_00371 1.2e-70 cymR K Transcriptional regulator
DOFFALOB_00372 4.7e-213 iscS 2.8.1.7 E Cysteine desulfurase
DOFFALOB_00373 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
DOFFALOB_00374 1.4e-15 S COG0457 FOG TPR repeat
DOFFALOB_00375 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
DOFFALOB_00376 1.8e-83 yrrD S protein conserved in bacteria
DOFFALOB_00377 9.8e-31 yrzR
DOFFALOB_00378 8e-08 S Protein of unknown function (DUF3918)
DOFFALOB_00379 7.6e-107 glnP P ABC transporter
DOFFALOB_00380 3.6e-109 gluC P ABC transporter
DOFFALOB_00381 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
DOFFALOB_00382 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
DOFFALOB_00383 2.7e-170 yrrI S AI-2E family transporter
DOFFALOB_00384 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DOFFALOB_00385 1.7e-41 yrzL S Belongs to the UPF0297 family
DOFFALOB_00386 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DOFFALOB_00387 1.2e-45 yrzB S Belongs to the UPF0473 family
DOFFALOB_00388 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DOFFALOB_00389 5.9e-120 yrrM 2.1.1.104 S O-methyltransferase
DOFFALOB_00390 7.8e-174 yegQ O Peptidase U32
DOFFALOB_00391 2.7e-246 yegQ O COG0826 Collagenase and related proteases
DOFFALOB_00392 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
DOFFALOB_00393 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DOFFALOB_00394 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
DOFFALOB_00395 4.2e-63 yrrS S Protein of unknown function (DUF1510)
DOFFALOB_00396 3.5e-26 yrzA S Protein of unknown function (DUF2536)
DOFFALOB_00397 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
DOFFALOB_00398 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DOFFALOB_00399 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
DOFFALOB_00400 2.6e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
DOFFALOB_00401 4.6e-35 yrhC S YrhC-like protein
DOFFALOB_00402 1.4e-78 yrhD S Protein of unknown function (DUF1641)
DOFFALOB_00403 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
DOFFALOB_00404 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
DOFFALOB_00405 1.8e-142 focA P Formate nitrite
DOFFALOB_00408 4.5e-97 yrhH Q methyltransferase
DOFFALOB_00409 4.8e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
DOFFALOB_00410 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
DOFFALOB_00411 1.5e-46 yrhK S YrhK-like protein
DOFFALOB_00412 0.0 yrhL I Acyltransferase family
DOFFALOB_00413 1.7e-151 rsiV S Protein of unknown function (DUF3298)
DOFFALOB_00414 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
DOFFALOB_00415 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
DOFFALOB_00416 3.6e-106 yrhP E LysE type translocator
DOFFALOB_00417 1.6e-255 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
DOFFALOB_00418 0.0 levR K PTS system fructose IIA component
DOFFALOB_00419 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
DOFFALOB_00420 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
DOFFALOB_00421 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
DOFFALOB_00422 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
DOFFALOB_00423 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
DOFFALOB_00424 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
DOFFALOB_00425 1.9e-200 adhA 1.1.1.1 C alcohol dehydrogenase
DOFFALOB_00426 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
DOFFALOB_00427 4.3e-47 yraB K helix_turn_helix, mercury resistance
DOFFALOB_00428 1.1e-49 yraD M Spore coat protein
DOFFALOB_00429 2.6e-26 yraE
DOFFALOB_00430 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
DOFFALOB_00431 6.4e-63 yraF M Spore coat protein
DOFFALOB_00432 5.3e-37 yraG
DOFFALOB_00433 1.3e-66 E Glyoxalase-like domain
DOFFALOB_00434 2.4e-61 T sh3 domain protein
DOFFALOB_00435 1.7e-60 T sh3 domain protein
DOFFALOB_00436 3.2e-155 S Alpha beta hydrolase
DOFFALOB_00437 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DOFFALOB_00438 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
DOFFALOB_00440 2.4e-206 yraM S PrpF protein
DOFFALOB_00441 1.2e-163 yraN K Transcriptional regulator
DOFFALOB_00442 9.5e-226 yraO C Citrate transporter
DOFFALOB_00443 4.5e-188 yrpG C Aldo/keto reductase family
DOFFALOB_00444 6.3e-96 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
DOFFALOB_00445 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
DOFFALOB_00447 3e-125 yrpD S Domain of unknown function, YrpD
DOFFALOB_00448 7.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
DOFFALOB_00449 1.5e-194 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
DOFFALOB_00450 7.6e-168 aadK G Streptomycin adenylyltransferase
DOFFALOB_00451 1.2e-91 yrdA S DinB family
DOFFALOB_00452 1.9e-57 S Protein of unknown function (DUF2568)
DOFFALOB_00453 3.1e-101 yrdC 3.5.1.19 Q Isochorismatase family
DOFFALOB_00455 4.1e-231 cypA C Cytochrome P450
DOFFALOB_00456 4.1e-46 yrdF K ribonuclease inhibitor
DOFFALOB_00457 2.2e-79 bkdR K helix_turn_helix ASNC type
DOFFALOB_00458 2.8e-137 azlC E AzlC protein
DOFFALOB_00459 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
DOFFALOB_00460 1.1e-226 brnQ E Component of the transport system for branched-chain amino acids
DOFFALOB_00462 2.5e-161 gltR K LysR substrate binding domain
DOFFALOB_00463 1.3e-66 yodA S tautomerase
DOFFALOB_00464 3.5e-158 czcD P COG1230 Co Zn Cd efflux system component
DOFFALOB_00465 2e-199 trkA P Oxidoreductase
DOFFALOB_00466 5.9e-160 yrdQ K Transcriptional regulator
DOFFALOB_00467 1.7e-171 yrdR EG EamA-like transporter family
DOFFALOB_00468 2.1e-17 S YrzO-like protein
DOFFALOB_00469 4.5e-236 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
DOFFALOB_00470 1.4e-83 bltD 2.3.1.57 K FR47-like protein
DOFFALOB_00471 3.5e-211 blt EGP Major facilitator Superfamily
DOFFALOB_00472 4.8e-151 bltR K helix_turn_helix, mercury resistance
DOFFALOB_00473 2.6e-108 yrkC G Cupin domain
DOFFALOB_00474 7.8e-39 yrkD S protein conserved in bacteria
DOFFALOB_00475 5.1e-84 yrkE O DsrE/DsrF/DrsH-like family
DOFFALOB_00476 1.7e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
DOFFALOB_00477 2.3e-212 yrkH P Rhodanese Homology Domain
DOFFALOB_00478 2.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
DOFFALOB_00479 4.3e-117 yrkJ S membrane transporter protein
DOFFALOB_00480 2.8e-79 S Protein of unknown function with HXXEE motif
DOFFALOB_00481 1.5e-97 ywrO S Flavodoxin-like fold
DOFFALOB_00482 6e-105 yrkN K Acetyltransferase (GNAT) family
DOFFALOB_00483 8.2e-224 yrkO P Protein of unknown function (DUF418)
DOFFALOB_00484 1.1e-127 T Transcriptional regulator
DOFFALOB_00485 9e-237 yrkQ T Histidine kinase
DOFFALOB_00486 2e-68 psiE S Protein PsiE homolog
DOFFALOB_00487 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DOFFALOB_00488 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
DOFFALOB_00489 2.3e-133 yqeB
DOFFALOB_00490 1.2e-171 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
DOFFALOB_00491 4.7e-106 yqeD S SNARE associated Golgi protein
DOFFALOB_00492 2.1e-137 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
DOFFALOB_00493 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
DOFFALOB_00495 5.3e-95 yqeG S hydrolase of the HAD superfamily
DOFFALOB_00496 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
DOFFALOB_00497 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DOFFALOB_00498 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
DOFFALOB_00499 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DOFFALOB_00500 7.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
DOFFALOB_00501 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DOFFALOB_00502 2.9e-139 yqeM Q Methyltransferase
DOFFALOB_00503 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DOFFALOB_00504 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
DOFFALOB_00505 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
DOFFALOB_00506 0.0 comEC S Competence protein ComEC
DOFFALOB_00507 4.1e-15 S YqzM-like protein
DOFFALOB_00508 1.1e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
DOFFALOB_00509 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
DOFFALOB_00510 1.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
DOFFALOB_00511 6.9e-223 spoIIP M stage II sporulation protein P
DOFFALOB_00512 1e-54 yqxA S Protein of unknown function (DUF3679)
DOFFALOB_00513 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DOFFALOB_00514 4.8e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
DOFFALOB_00515 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DOFFALOB_00516 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DOFFALOB_00517 0.0 dnaK O Heat shock 70 kDa protein
DOFFALOB_00518 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DOFFALOB_00519 5.4e-175 prmA J Methylates ribosomal protein L11
DOFFALOB_00520 1.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
DOFFALOB_00521 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
DOFFALOB_00522 1.6e-158 yqeW P COG1283 Na phosphate symporter
DOFFALOB_00523 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
DOFFALOB_00524 2.5e-61 yqeY S Yqey-like protein
DOFFALOB_00525 5.4e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
DOFFALOB_00526 4.3e-122 yqfA S UPF0365 protein
DOFFALOB_00527 6e-25 yqfB
DOFFALOB_00528 2.7e-45 yqfC S sporulation protein YqfC
DOFFALOB_00529 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
DOFFALOB_00530 1.1e-175 phoH T Phosphate starvation-inducible protein PhoH
DOFFALOB_00532 0.0 yqfF S membrane-associated HD superfamily hydrolase
DOFFALOB_00533 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DOFFALOB_00534 1.6e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
DOFFALOB_00535 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
DOFFALOB_00536 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DOFFALOB_00537 8.4e-19 S YqzL-like protein
DOFFALOB_00538 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
DOFFALOB_00539 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
DOFFALOB_00540 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
DOFFALOB_00541 4.5e-112 ccpN K CBS domain
DOFFALOB_00542 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
DOFFALOB_00543 4.5e-88 yaiI S Belongs to the UPF0178 family
DOFFALOB_00544 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DOFFALOB_00545 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DOFFALOB_00546 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
DOFFALOB_00547 6.1e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
DOFFALOB_00548 5.1e-212 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DOFFALOB_00549 2.6e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DOFFALOB_00550 2.9e-14 yqfQ S YqfQ-like protein
DOFFALOB_00551 1.7e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
DOFFALOB_00552 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DOFFALOB_00553 2.1e-36 yqfT S Protein of unknown function (DUF2624)
DOFFALOB_00554 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
DOFFALOB_00555 1.9e-77 zur P Belongs to the Fur family
DOFFALOB_00556 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
DOFFALOB_00557 4.3e-62 yqfX S membrane
DOFFALOB_00558 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DOFFALOB_00559 5.2e-47 yqfZ M LysM domain
DOFFALOB_00560 2.2e-75 yqgA
DOFFALOB_00561 8.5e-134 yqgB S Protein of unknown function (DUF1189)
DOFFALOB_00562 4e-73 yqgC S protein conserved in bacteria
DOFFALOB_00563 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
DOFFALOB_00564 2.5e-231 yqgE EGP Major facilitator superfamily
DOFFALOB_00565 0.0 pbpA 3.4.16.4 M penicillin-binding protein
DOFFALOB_00566 5.3e-151 pstS P Phosphate
DOFFALOB_00567 1.3e-160 pstC P probably responsible for the translocation of the substrate across the membrane
DOFFALOB_00568 4.4e-158 pstA P Phosphate transport system permease
DOFFALOB_00569 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DOFFALOB_00570 9.8e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DOFFALOB_00571 1.9e-75 yqzC S YceG-like family
DOFFALOB_00572 9.2e-51 yqzD
DOFFALOB_00574 3.2e-203 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
DOFFALOB_00575 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
DOFFALOB_00576 2.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DOFFALOB_00577 2.5e-09 yqgO
DOFFALOB_00578 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
DOFFALOB_00579 3.1e-33 yqgQ S Protein conserved in bacteria
DOFFALOB_00580 5.2e-181 glcK 2.7.1.2 G Glucokinase
DOFFALOB_00581 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
DOFFALOB_00582 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
DOFFALOB_00583 2.7e-199 yqgU
DOFFALOB_00584 6.9e-50 yqgV S Thiamine-binding protein
DOFFALOB_00585 8.9e-23 yqgW S Protein of unknown function (DUF2759)
DOFFALOB_00586 1.9e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
DOFFALOB_00587 1.8e-37 yqgY S Protein of unknown function (DUF2626)
DOFFALOB_00588 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
DOFFALOB_00590 1.7e-151 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
DOFFALOB_00591 5.2e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
DOFFALOB_00592 7.2e-175 corA P Mg2 transporter protein
DOFFALOB_00594 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DOFFALOB_00595 1.6e-175 comGB NU COG1459 Type II secretory pathway, component PulF
DOFFALOB_00596 1.4e-47 comGC U Required for transformation and DNA binding
DOFFALOB_00597 4.4e-71 gspH NU protein transport across the cell outer membrane
DOFFALOB_00598 1.1e-59 comGE
DOFFALOB_00599 5.5e-49 comGF U Putative Competence protein ComGF
DOFFALOB_00600 3.7e-42 S ComG operon protein 7
DOFFALOB_00601 1.4e-26 yqzE S YqzE-like protein
DOFFALOB_00602 7.3e-54 yqzG S Protein of unknown function (DUF3889)
DOFFALOB_00603 2.8e-113 yqxM
DOFFALOB_00604 2.5e-58 sipW 3.4.21.89 U Signal peptidase
DOFFALOB_00605 1.9e-141 tasA S Cell division protein FtsN
DOFFALOB_00606 1e-54 sinR K transcriptional
DOFFALOB_00607 1.2e-24 sinI S Anti-repressor SinI
DOFFALOB_00608 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
DOFFALOB_00609 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
DOFFALOB_00610 1.8e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
DOFFALOB_00611 3.4e-255 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DOFFALOB_00612 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DOFFALOB_00613 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
DOFFALOB_00614 5.2e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
DOFFALOB_00615 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
DOFFALOB_00616 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
DOFFALOB_00617 2.2e-61 yqhP
DOFFALOB_00618 2.1e-174 yqhQ S Protein of unknown function (DUF1385)
DOFFALOB_00619 2.3e-93 yqhR S Conserved membrane protein YqhR
DOFFALOB_00620 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
DOFFALOB_00621 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
DOFFALOB_00622 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DOFFALOB_00623 7.9e-37 yqhV S Protein of unknown function (DUF2619)
DOFFALOB_00624 1.2e-171 spoIIIAA S stage III sporulation protein AA
DOFFALOB_00625 2.9e-85 spoIIIAB S Stage III sporulation protein
DOFFALOB_00626 7.6e-29 spoIIIAC S stage III sporulation protein AC
DOFFALOB_00627 2.3e-58 spoIIIAD S Stage III sporulation protein AD
DOFFALOB_00628 1.3e-197 spoIIIAE S stage III sporulation protein AE
DOFFALOB_00629 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
DOFFALOB_00630 6.9e-103 spoIIIAG S stage III sporulation protein AG
DOFFALOB_00631 9.9e-91 spoIIIAH S SpoIIIAH-like protein
DOFFALOB_00632 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
DOFFALOB_00633 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
DOFFALOB_00634 2.1e-67 yqhY S protein conserved in bacteria
DOFFALOB_00635 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DOFFALOB_00636 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DOFFALOB_00637 2.2e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DOFFALOB_00638 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DOFFALOB_00639 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
DOFFALOB_00640 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DOFFALOB_00641 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
DOFFALOB_00642 1.7e-78 argR K Regulates arginine biosynthesis genes
DOFFALOB_00643 0.0 recN L May be involved in recombinational repair of damaged DNA
DOFFALOB_00644 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
DOFFALOB_00645 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
DOFFALOB_00647 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
DOFFALOB_00648 5.9e-27
DOFFALOB_00649 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
DOFFALOB_00650 1.8e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
DOFFALOB_00651 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
DOFFALOB_00652 4.7e-157 hbdA 1.1.1.157 I Dehydrogenase
DOFFALOB_00653 1.8e-212 mmgC I acyl-CoA dehydrogenase
DOFFALOB_00654 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
DOFFALOB_00655 5.7e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
DOFFALOB_00656 7.1e-164 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DOFFALOB_00657 4e-34 yqzF S Protein of unknown function (DUF2627)
DOFFALOB_00658 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
DOFFALOB_00659 7.1e-156 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
DOFFALOB_00660 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
DOFFALOB_00661 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
DOFFALOB_00662 3.4e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
DOFFALOB_00663 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
DOFFALOB_00664 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
DOFFALOB_00665 3.5e-233 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
DOFFALOB_00666 2.6e-152 bmrR K helix_turn_helix, mercury resistance
DOFFALOB_00667 7.9e-208 norA EGP Major facilitator Superfamily
DOFFALOB_00668 8.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
DOFFALOB_00669 9.3e-77 yqiW S Belongs to the UPF0403 family
DOFFALOB_00670 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
DOFFALOB_00671 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
DOFFALOB_00672 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
DOFFALOB_00673 1.1e-175 yqjA S Putative aromatic acid exporter C-terminal domain
DOFFALOB_00674 1.4e-98 yqjB S protein conserved in bacteria
DOFFALOB_00676 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
DOFFALOB_00677 4.4e-291 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
DOFFALOB_00678 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
DOFFALOB_00679 3.6e-142 yqjF S Uncharacterized conserved protein (COG2071)
DOFFALOB_00680 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DOFFALOB_00681 4.5e-24 yqzJ
DOFFALOB_00682 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DOFFALOB_00683 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DOFFALOB_00684 1.6e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DOFFALOB_00685 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
DOFFALOB_00686 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
DOFFALOB_00687 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
DOFFALOB_00688 0.0 rocB E arginine degradation protein
DOFFALOB_00689 8.6e-148 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DOFFALOB_00690 3.4e-180 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
DOFFALOB_00691 3.5e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
DOFFALOB_00692 2.4e-264 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
DOFFALOB_00693 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
DOFFALOB_00694 7.2e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DOFFALOB_00696 5.2e-226 yqjV G Major Facilitator Superfamily
DOFFALOB_00698 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DOFFALOB_00699 2.2e-49 S YolD-like protein
DOFFALOB_00700 3.6e-87 yqjY K acetyltransferase
DOFFALOB_00701 8e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
DOFFALOB_00702 4.7e-196 yqkA K GrpB protein
DOFFALOB_00703 2.8e-54 yqkB S Belongs to the HesB IscA family
DOFFALOB_00704 9.4e-39 yqkC S Protein of unknown function (DUF2552)
DOFFALOB_00705 2.4e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
DOFFALOB_00706 4e-14 yqkE S Protein of unknown function (DUF3886)
DOFFALOB_00707 4.4e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
DOFFALOB_00709 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
DOFFALOB_00710 3e-223 yqxK 3.6.4.12 L DNA helicase
DOFFALOB_00711 4.5e-58 ansR K Transcriptional regulator
DOFFALOB_00712 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
DOFFALOB_00713 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
DOFFALOB_00714 3.1e-235 mleN C Na H antiporter
DOFFALOB_00715 5.5e-242 mleA 1.1.1.38 C malic enzyme
DOFFALOB_00716 2e-32 yqkK
DOFFALOB_00717 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
DOFFALOB_00718 2.4e-80 fur P Belongs to the Fur family
DOFFALOB_00719 3.7e-37 S Protein of unknown function (DUF4227)
DOFFALOB_00720 2.6e-166 xerD L recombinase XerD
DOFFALOB_00721 1.2e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
DOFFALOB_00722 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DOFFALOB_00723 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
DOFFALOB_00724 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
DOFFALOB_00725 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
DOFFALOB_00726 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DOFFALOB_00727 7.4e-112 spoVAA S Stage V sporulation protein AA
DOFFALOB_00728 1e-67 spoVAB S Stage V sporulation protein AB
DOFFALOB_00729 2.3e-78 spoVAC S stage V sporulation protein AC
DOFFALOB_00730 9e-192 spoVAD I Stage V sporulation protein AD
DOFFALOB_00731 2.2e-57 spoVAEB S stage V sporulation protein
DOFFALOB_00732 1.4e-110 spoVAEA S stage V sporulation protein
DOFFALOB_00733 1.4e-273 spoVAF EG Stage V sporulation protein AF
DOFFALOB_00734 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DOFFALOB_00735 1.3e-149 ypuA S Secreted protein
DOFFALOB_00736 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DOFFALOB_00739 1.5e-17 S SNARE associated Golgi protein
DOFFALOB_00740 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
DOFFALOB_00741 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
DOFFALOB_00742 6e-55 ypuD
DOFFALOB_00743 1.3e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DOFFALOB_00744 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
DOFFALOB_00745 9.8e-230 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DOFFALOB_00746 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
DOFFALOB_00747 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DOFFALOB_00748 4.5e-94 ypuF S Domain of unknown function (DUF309)
DOFFALOB_00749 4.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DOFFALOB_00750 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DOFFALOB_00751 4e-98 ypuI S Protein of unknown function (DUF3907)
DOFFALOB_00752 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
DOFFALOB_00753 3.5e-103 spmA S Spore maturation protein
DOFFALOB_00754 1.9e-87 spmB S Spore maturation protein
DOFFALOB_00755 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DOFFALOB_00756 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
DOFFALOB_00757 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
DOFFALOB_00758 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
DOFFALOB_00759 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DOFFALOB_00760 0.0 resE 2.7.13.3 T Histidine kinase
DOFFALOB_00761 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
DOFFALOB_00762 6.8e-201 rsiX
DOFFALOB_00763 9e-136 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
DOFFALOB_00764 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DOFFALOB_00765 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DOFFALOB_00766 4.7e-41 fer C Ferredoxin
DOFFALOB_00767 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
DOFFALOB_00768 3.2e-286 recQ 3.6.4.12 L DNA helicase
DOFFALOB_00769 2.2e-100 ypbD S metal-dependent membrane protease
DOFFALOB_00770 4.6e-81 ypbE M Lysin motif
DOFFALOB_00771 2.8e-81 ypbF S Protein of unknown function (DUF2663)
DOFFALOB_00772 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
DOFFALOB_00773 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
DOFFALOB_00774 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
DOFFALOB_00775 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
DOFFALOB_00776 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
DOFFALOB_00777 4.7e-155 sleB 3.5.1.28 M Spore cortex-lytic enzyme
DOFFALOB_00778 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
DOFFALOB_00779 9.2e-113 ypfA M Flagellar protein YcgR
DOFFALOB_00780 1.8e-23 S Family of unknown function (DUF5359)
DOFFALOB_00781 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
DOFFALOB_00782 4.3e-206 rpsA 1.17.7.4 J Ribosomal protein S1
DOFFALOB_00783 4.1e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
DOFFALOB_00784 1e-07 S YpzI-like protein
DOFFALOB_00785 1.3e-102 yphA
DOFFALOB_00786 2.5e-161 seaA S YIEGIA protein
DOFFALOB_00787 1.6e-28 ypzH
DOFFALOB_00788 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
DOFFALOB_00789 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
DOFFALOB_00790 1.6e-18 yphE S Protein of unknown function (DUF2768)
DOFFALOB_00791 5.4e-138 yphF
DOFFALOB_00792 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DOFFALOB_00793 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DOFFALOB_00794 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
DOFFALOB_00795 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
DOFFALOB_00796 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
DOFFALOB_00797 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
DOFFALOB_00798 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
DOFFALOB_00799 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
DOFFALOB_00800 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
DOFFALOB_00801 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DOFFALOB_00802 8.1e-207 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DOFFALOB_00803 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
DOFFALOB_00804 6.6e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DOFFALOB_00805 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DOFFALOB_00806 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
DOFFALOB_00807 6.5e-119 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
DOFFALOB_00808 4e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DOFFALOB_00809 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
DOFFALOB_00810 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DOFFALOB_00811 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
DOFFALOB_00812 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
DOFFALOB_00813 4.1e-234 S COG0457 FOG TPR repeat
DOFFALOB_00814 2.8e-99 ypiB S Belongs to the UPF0302 family
DOFFALOB_00815 8.5e-78 ypiF S Protein of unknown function (DUF2487)
DOFFALOB_00816 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
DOFFALOB_00817 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
DOFFALOB_00818 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
DOFFALOB_00819 2e-98 ypjA S membrane
DOFFALOB_00820 6.1e-143 ypjB S sporulation protein
DOFFALOB_00821 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
DOFFALOB_00822 2.6e-55 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
DOFFALOB_00823 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
DOFFALOB_00824 6.5e-72 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
DOFFALOB_00825 6.9e-130 bshB1 S proteins, LmbE homologs
DOFFALOB_00826 3.7e-210 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
DOFFALOB_00827 4.4e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DOFFALOB_00828 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
DOFFALOB_00829 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
DOFFALOB_00830 1.2e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DOFFALOB_00831 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DOFFALOB_00832 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
DOFFALOB_00833 6.7e-23 ypmA S Protein of unknown function (DUF4264)
DOFFALOB_00834 3.4e-80 ypmB S protein conserved in bacteria
DOFFALOB_00835 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
DOFFALOB_00836 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
DOFFALOB_00837 5.7e-129 dnaD L DNA replication protein DnaD
DOFFALOB_00838 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DOFFALOB_00839 4.7e-93 ypoC
DOFFALOB_00840 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
DOFFALOB_00841 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
DOFFALOB_00842 2.6e-188 yppC S Protein of unknown function (DUF2515)
DOFFALOB_00845 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
DOFFALOB_00847 1.2e-48 yppG S YppG-like protein
DOFFALOB_00848 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
DOFFALOB_00849 1.9e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
DOFFALOB_00850 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
DOFFALOB_00851 1.3e-237 yprB L RNase_H superfamily
DOFFALOB_00852 3.3e-92 ypsA S Belongs to the UPF0398 family
DOFFALOB_00853 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
DOFFALOB_00854 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
DOFFALOB_00856 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
DOFFALOB_00857 7.1e-133 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DOFFALOB_00858 1.7e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
DOFFALOB_00859 3.9e-187 ptxS K transcriptional
DOFFALOB_00860 2.9e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
DOFFALOB_00861 7e-104 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
DOFFALOB_00862 5e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
DOFFALOB_00863 4.2e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DOFFALOB_00864 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DOFFALOB_00865 1.6e-228 pbuX F xanthine
DOFFALOB_00866 4.4e-208 bcsA Q Naringenin-chalcone synthase
DOFFALOB_00867 5.1e-87 ypbQ S protein conserved in bacteria
DOFFALOB_00868 0.0 ypbR S Dynamin family
DOFFALOB_00869 1e-38 ypbS S Protein of unknown function (DUF2533)
DOFFALOB_00870 2e-07
DOFFALOB_00871 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
DOFFALOB_00873 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
DOFFALOB_00874 5.4e-107 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DOFFALOB_00875 8.9e-127 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
DOFFALOB_00876 2.6e-27 ypeQ S Zinc-finger
DOFFALOB_00877 8.1e-31 S Protein of unknown function (DUF2564)
DOFFALOB_00878 3.8e-16 degR
DOFFALOB_00879 7.9e-31 cspD K Cold-shock protein
DOFFALOB_00880 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
DOFFALOB_00881 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DOFFALOB_00882 2.3e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
DOFFALOB_00883 3.1e-110 ypgQ S phosphohydrolase
DOFFALOB_00884 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
DOFFALOB_00885 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
DOFFALOB_00886 1.7e-75 yphP S Belongs to the UPF0403 family
DOFFALOB_00887 1.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
DOFFALOB_00888 7.8e-114 ypjP S YpjP-like protein
DOFFALOB_00889 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
DOFFALOB_00890 4.3e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DOFFALOB_00891 7.9e-96 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DOFFALOB_00892 7.4e-112 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
DOFFALOB_00893 4.2e-110 hlyIII S protein, Hemolysin III
DOFFALOB_00894 1.6e-185 pspF K Transcriptional regulator
DOFFALOB_00895 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DOFFALOB_00896 3.1e-40 ypmP S Protein of unknown function (DUF2535)
DOFFALOB_00897 3.2e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
DOFFALOB_00898 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
DOFFALOB_00899 5e-99 ypmS S protein conserved in bacteria
DOFFALOB_00900 5.5e-29 ypmT S Uncharacterized ympT
DOFFALOB_00901 2.6e-223 mepA V MATE efflux family protein
DOFFALOB_00902 1.6e-70 ypoP K transcriptional
DOFFALOB_00903 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DOFFALOB_00904 1.4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
DOFFALOB_00905 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
DOFFALOB_00906 3.6e-213 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
DOFFALOB_00907 3.3e-188 cgeB S Spore maturation protein
DOFFALOB_00908 1.2e-65 cgeA
DOFFALOB_00909 3.5e-38 cgeC
DOFFALOB_00910 1e-256 cgeD M maturation of the outermost layer of the spore
DOFFALOB_00911 2.9e-145 yiiD K acetyltransferase
DOFFALOB_00914 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DOFFALOB_00915 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DOFFALOB_00916 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
DOFFALOB_00917 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
DOFFALOB_00918 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
DOFFALOB_00919 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
DOFFALOB_00920 2.9e-47 yokU S YokU-like protein, putative antitoxin
DOFFALOB_00921 1.4e-36 yozE S Belongs to the UPF0346 family
DOFFALOB_00922 1.4e-124 yodN
DOFFALOB_00924 2.8e-24 yozD S YozD-like protein
DOFFALOB_00925 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
DOFFALOB_00926 3.6e-54 yodL S YodL-like
DOFFALOB_00927 5.3e-09
DOFFALOB_00928 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
DOFFALOB_00929 2.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
DOFFALOB_00930 5.2e-24 yodI
DOFFALOB_00931 1.7e-128 yodH Q Methyltransferase
DOFFALOB_00932 1.9e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
DOFFALOB_00933 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DOFFALOB_00934 6.2e-28 S Protein of unknown function (DUF3311)
DOFFALOB_00935 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
DOFFALOB_00936 3.8e-113 mhqD S Carboxylesterase
DOFFALOB_00937 4.8e-108 yodC C nitroreductase
DOFFALOB_00938 1.7e-57 yodB K transcriptional
DOFFALOB_00939 3.8e-66 yodA S tautomerase
DOFFALOB_00940 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
DOFFALOB_00941 3.4e-09
DOFFALOB_00942 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
DOFFALOB_00943 3.5e-163 rarD S -transporter
DOFFALOB_00944 1.5e-43
DOFFALOB_00945 2.2e-60 yojF S Protein of unknown function (DUF1806)
DOFFALOB_00946 2.1e-125 yojG S deacetylase
DOFFALOB_00947 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
DOFFALOB_00948 4.2e-245 norM V Multidrug efflux pump
DOFFALOB_00950 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DOFFALOB_00951 1.8e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
DOFFALOB_00952 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
DOFFALOB_00953 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DOFFALOB_00954 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
DOFFALOB_00955 0.0 yojO P Von Willebrand factor
DOFFALOB_00956 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
DOFFALOB_00957 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
DOFFALOB_00958 5.1e-168 yocS S -transporter
DOFFALOB_00959 3.4e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
DOFFALOB_00960 5.4e-166 sodA 1.15.1.1 P Superoxide dismutase
DOFFALOB_00961 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
DOFFALOB_00962 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
DOFFALOB_00963 2.7e-31 yozC
DOFFALOB_00964 4.2e-56 yozO S Bacterial PH domain
DOFFALOB_00965 1.9e-36 yocN
DOFFALOB_00966 1.1e-40 yozN
DOFFALOB_00967 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
DOFFALOB_00968 6.6e-34
DOFFALOB_00969 6.4e-54 yocL
DOFFALOB_00970 3.3e-83 dksA T general stress protein
DOFFALOB_00971 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DOFFALOB_00972 0.0 recQ 3.6.4.12 L DNA helicase
DOFFALOB_00973 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
DOFFALOB_00974 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DOFFALOB_00975 3.2e-198 desK 2.7.13.3 T Histidine kinase
DOFFALOB_00976 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
DOFFALOB_00977 6.9e-189 yocD 3.4.17.13 V peptidase S66
DOFFALOB_00978 1.9e-94 yocC
DOFFALOB_00979 2.2e-145
DOFFALOB_00980 1.5e-92 yozB S membrane
DOFFALOB_00981 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
DOFFALOB_00982 1e-51 czrA K transcriptional
DOFFALOB_00983 2.5e-95 yobW
DOFFALOB_00984 9e-178 yobV K WYL domain
DOFFALOB_00985 1.5e-88 yobU K Bacterial transcription activator, effector binding domain
DOFFALOB_00986 4.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
DOFFALOB_00987 3e-99 yobS K Transcriptional regulator
DOFFALOB_00988 2.5e-143 yobR 2.3.1.1 J FR47-like protein
DOFFALOB_00989 1e-136 yobQ K helix_turn_helix, arabinose operon control protein
DOFFALOB_00990 9.9e-55 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
DOFFALOB_00991 0.0 yobO M Pectate lyase superfamily protein
DOFFALOB_00992 9.5e-280 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
DOFFALOB_00993 7.9e-105 yokH G SMI1 / KNR4 family
DOFFALOB_00994 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
DOFFALOB_00995 3e-86 S SMI1-KNR4 cell-wall
DOFFALOB_00996 2.7e-157 yobJ
DOFFALOB_00997 0.0 K Psort location Cytoplasmic, score
DOFFALOB_00998 1.2e-49
DOFFALOB_00999 2.6e-38 S YolD-like protein
DOFFALOB_01000 1.4e-59 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DOFFALOB_01001 1.2e-123 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DOFFALOB_01003 1.7e-207 S aspartate phosphatase
DOFFALOB_01008 1.8e-178 yobF
DOFFALOB_01009 6.6e-127 yoqW S Belongs to the SOS response-associated peptidase family
DOFFALOB_01010 1.6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
DOFFALOB_01012 5.7e-58 K Helix-turn-helix
DOFFALOB_01013 1.4e-37 S TM2 domain
DOFFALOB_01014 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
DOFFALOB_01015 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
DOFFALOB_01019 2.3e-170 bla 3.5.2.6 V beta-lactamase
DOFFALOB_01020 1.1e-118 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
DOFFALOB_01021 3.7e-78 yoaW
DOFFALOB_01022 6e-160 yijE EG EamA-like transporter family
DOFFALOB_01023 8.6e-159 yoaU K LysR substrate binding domain
DOFFALOB_01024 1.1e-149 yoaT S Protein of unknown function (DUF817)
DOFFALOB_01025 4.2e-37 yozG K Transcriptional regulator
DOFFALOB_01026 4.3e-75 yoaS S Protein of unknown function (DUF2975)
DOFFALOB_01027 2.4e-172 yoaR V vancomycin resistance protein
DOFFALOB_01028 4.1e-89
DOFFALOB_01029 1.2e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
DOFFALOB_01030 1.9e-146 yoaP 3.1.3.18 K YoaP-like
DOFFALOB_01032 3.8e-234 oxdC 4.1.1.2 G Oxalate decarboxylase
DOFFALOB_01034 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
DOFFALOB_01035 2.5e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
DOFFALOB_01036 2.3e-111 yoaK S Membrane
DOFFALOB_01037 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
DOFFALOB_01038 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
DOFFALOB_01039 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
DOFFALOB_01040 1.5e-38 S Protein of unknown function (DUF4025)
DOFFALOB_01041 7e-14
DOFFALOB_01042 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
DOFFALOB_01043 1.9e-33 yoaF
DOFFALOB_01044 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DOFFALOB_01045 1.7e-190 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DOFFALOB_01046 1e-284 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
DOFFALOB_01047 6.2e-235 yoaB EGP Major facilitator Superfamily
DOFFALOB_01048 7.5e-97 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
DOFFALOB_01049 3.1e-144 yoxB
DOFFALOB_01050 3e-42 yoxC S Bacterial protein of unknown function (DUF948)
DOFFALOB_01051 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
DOFFALOB_01052 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
DOFFALOB_01053 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DOFFALOB_01054 4.1e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DOFFALOB_01055 7.8e-155 gltC K Transcriptional regulator
DOFFALOB_01056 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
DOFFALOB_01057 2.7e-293 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
DOFFALOB_01058 5e-187 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
DOFFALOB_01059 2.5e-158 gltR1 K Transcriptional regulator
DOFFALOB_01060 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
DOFFALOB_01061 3e-34 yoeD G Helix-turn-helix domain
DOFFALOB_01062 2.2e-96 L Integrase
DOFFALOB_01064 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
DOFFALOB_01065 2.3e-246 yoeA V MATE efflux family protein
DOFFALOB_01066 9e-189 yoxA 5.1.3.3 G Aldose 1-epimerase
DOFFALOB_01067 4.3e-275 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
DOFFALOB_01068 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DOFFALOB_01069 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DOFFALOB_01070 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DOFFALOB_01071 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DOFFALOB_01072 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
DOFFALOB_01073 2.8e-64 yngL S Protein of unknown function (DUF1360)
DOFFALOB_01074 1.3e-306 yngK T Glycosyl hydrolase-like 10
DOFFALOB_01075 1.8e-31 S Family of unknown function (DUF5367)
DOFFALOB_01076 4.4e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
DOFFALOB_01077 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
DOFFALOB_01078 3e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
DOFFALOB_01079 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
DOFFALOB_01080 8e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
DOFFALOB_01081 2.2e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
DOFFALOB_01082 6.3e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
DOFFALOB_01083 1.9e-233 nrnB S phosphohydrolase (DHH superfamily)
DOFFALOB_01084 5.5e-104 yngC S membrane-associated protein
DOFFALOB_01085 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
DOFFALOB_01086 2.4e-80 yngA S membrane
DOFFALOB_01087 4.4e-299 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
DOFFALOB_01088 3.7e-251 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
DOFFALOB_01090 2.4e-297 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
DOFFALOB_01091 8.2e-252 agcS E Sodium alanine symporter
DOFFALOB_01092 1.3e-57 ynfC
DOFFALOB_01093 2.3e-12
DOFFALOB_01094 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DOFFALOB_01095 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DOFFALOB_01096 6.6e-69 yccU S CoA-binding protein
DOFFALOB_01097 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
DOFFALOB_01098 4.1e-49 yneR S Belongs to the HesB IscA family
DOFFALOB_01099 1.3e-53 yneQ
DOFFALOB_01100 1.2e-73 yneP S Thioesterase-like superfamily
DOFFALOB_01101 3.9e-35 tlp S Belongs to the Tlp family
DOFFALOB_01102 3.1e-08 sspN S Small acid-soluble spore protein N family
DOFFALOB_01104 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DOFFALOB_01105 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DOFFALOB_01106 2.2e-14 sspO S Belongs to the SspO family
DOFFALOB_01107 3.9e-19 sspP S Belongs to the SspP family
DOFFALOB_01108 4.1e-65 hspX O Spore coat protein
DOFFALOB_01109 4.2e-74 yneK S Protein of unknown function (DUF2621)
DOFFALOB_01110 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
DOFFALOB_01111 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
DOFFALOB_01112 7.1e-127 ccdA O cytochrome c biogenesis protein
DOFFALOB_01113 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
DOFFALOB_01114 1.8e-28 yneF S UPF0154 protein
DOFFALOB_01115 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
DOFFALOB_01116 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DOFFALOB_01117 1.3e-32 ynzC S UPF0291 protein
DOFFALOB_01118 9.2e-113 yneB L resolvase
DOFFALOB_01119 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
DOFFALOB_01120 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DOFFALOB_01122 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
DOFFALOB_01123 5.8e-74 yndM S Protein of unknown function (DUF2512)
DOFFALOB_01124 8.6e-139 yndL S Replication protein
DOFFALOB_01126 0.0 yndJ S YndJ-like protein
DOFFALOB_01127 2.6e-117 yndH S Domain of unknown function (DUF4166)
DOFFALOB_01128 7.7e-154 yndG S DoxX-like family
DOFFALOB_01129 4.2e-220 gerLC S Spore germination protein
DOFFALOB_01130 4.5e-197 gerAB U Spore germination
DOFFALOB_01131 5.7e-286 gerAA EG Spore germination protein
DOFFALOB_01134 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
DOFFALOB_01135 1.8e-71
DOFFALOB_01136 7.9e-25 tatA U protein secretion
DOFFALOB_01139 1.3e-134 S Domain of unknown function, YrpD
DOFFALOB_01141 1.2e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DOFFALOB_01144 5.2e-15
DOFFALOB_01145 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
DOFFALOB_01146 6.3e-84 yncE S Protein of unknown function (DUF2691)
DOFFALOB_01147 2.7e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DOFFALOB_01148 3.5e-247 iolT EGP Major facilitator Superfamily
DOFFALOB_01149 1.4e-113 yokF 3.1.31.1 L RNA catabolic process
DOFFALOB_01150 6e-293 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
DOFFALOB_01151 4e-264 xylA 5.3.1.5 G Belongs to the xylose isomerase family
DOFFALOB_01152 1e-215 xylR GK ROK family
DOFFALOB_01153 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
DOFFALOB_01154 2.7e-255 xynT G MFS/sugar transport protein
DOFFALOB_01155 1.1e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
DOFFALOB_01158 6.4e-60 ynaF
DOFFALOB_01159 1.9e-123 ynaE S Domain of unknown function (DUF3885)
DOFFALOB_01160 2e-99 ynaD J Acetyltransferase (GNAT) domain
DOFFALOB_01161 4.9e-145 ynaC
DOFFALOB_01162 6.8e-80 G regulation of fungal-type cell wall biogenesis
DOFFALOB_01163 5.8e-39
DOFFALOB_01164 2.5e-32
DOFFALOB_01165 5e-10
DOFFALOB_01169 5.6e-110 S aspartate phosphatase
DOFFALOB_01170 5.9e-177 A Pre-toxin TG
DOFFALOB_01171 2.7e-65 S Immunity protein 70
DOFFALOB_01172 5.4e-125 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
DOFFALOB_01173 2.1e-57 S Bacteriophage holin family
DOFFALOB_01176 2.5e-104 S Domain of unknown function (DUF2479)
DOFFALOB_01177 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
DOFFALOB_01178 1.2e-220 NU Prophage endopeptidase tail
DOFFALOB_01179 1.3e-111 S Phage tail protein
DOFFALOB_01180 0.0 D phage tail tape measure protein
DOFFALOB_01183 8.1e-79 S Phage tail tube protein
DOFFALOB_01185 2.3e-50 S Bacteriophage HK97-gp10, putative tail-component
DOFFALOB_01186 1.8e-37 S Phage head-tail joining protein
DOFFALOB_01187 1.7e-37 S Phage gp6-like head-tail connector protein
DOFFALOB_01188 1.7e-20
DOFFALOB_01189 5.6e-154 gp36 S capsid protein
DOFFALOB_01190 3.4e-80 S peptidase activity
DOFFALOB_01191 2.2e-174 S Phage portal protein
DOFFALOB_01192 8.6e-304 S Terminase
DOFFALOB_01193 6.8e-79 L phage terminase small subunit
DOFFALOB_01194 6.2e-50 V HNH endonuclease
DOFFALOB_01197 8.8e-29
DOFFALOB_01198 1.8e-44
DOFFALOB_01199 4.9e-84 S Domain of unknown function (DUF4868)
DOFFALOB_01200 1.8e-88 yrdC 3.5.1.19 Q Isochorismatase family
DOFFALOB_01204 3.5e-50 wecC 1.1.1.336 M ArpU family transcriptional regulator
DOFFALOB_01206 6.9e-19 S Phage-like element PBSX protein XtrA
DOFFALOB_01207 3.2e-22
DOFFALOB_01208 1.5e-170 dnaB 3.6.4.12 L replicative DNA helicase
DOFFALOB_01209 1.8e-25 S Loader and inhibitor of phage G40P
DOFFALOB_01210 1.2e-82 L DnaD domain protein
DOFFALOB_01212 4.1e-12
DOFFALOB_01213 8.4e-82 S Phage regulatory protein Rha (Phage_pRha)
DOFFALOB_01215 3.6e-23
DOFFALOB_01217 5.3e-25 K Helix-turn-helix XRE-family like proteins
DOFFALOB_01218 2.7e-42 E Zn peptidase
DOFFALOB_01219 4.1e-132 L Belongs to the 'phage' integrase family
DOFFALOB_01220 7e-261 glnA 6.3.1.2 E glutamine synthetase
DOFFALOB_01221 1.1e-68 glnR K transcriptional
DOFFALOB_01222 3.3e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
DOFFALOB_01223 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DOFFALOB_01224 1.7e-176 spoVK O stage V sporulation protein K
DOFFALOB_01225 8e-116 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
DOFFALOB_01226 2e-109 ymaB
DOFFALOB_01227 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DOFFALOB_01228 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DOFFALOB_01229 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
DOFFALOB_01230 4.5e-22 ymzA
DOFFALOB_01231 6.3e-23
DOFFALOB_01232 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
DOFFALOB_01233 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DOFFALOB_01234 2.1e-46 ymaF S YmaF family
DOFFALOB_01236 4.9e-51 ebrA P Small Multidrug Resistance protein
DOFFALOB_01237 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
DOFFALOB_01238 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
DOFFALOB_01239 2.1e-126 ymaC S Replication protein
DOFFALOB_01240 4.6e-252 aprX O Belongs to the peptidase S8 family
DOFFALOB_01241 6.6e-164 ymaE S Metallo-beta-lactamase superfamily
DOFFALOB_01242 1.2e-61 ymzB
DOFFALOB_01243 2.5e-233 cypA C Cytochrome P450
DOFFALOB_01244 0.0 pks13 HQ Beta-ketoacyl synthase
DOFFALOB_01245 0.0 dhbF IQ polyketide synthase
DOFFALOB_01246 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
DOFFALOB_01247 0.0 pfaA Q Polyketide synthase of type I
DOFFALOB_01248 0.0 rhiB IQ polyketide synthase
DOFFALOB_01249 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
DOFFALOB_01250 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
DOFFALOB_01251 1.3e-245 pksG 2.3.3.10 I synthase
DOFFALOB_01252 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
DOFFALOB_01253 1.4e-37 acpK IQ Phosphopantetheine attachment site
DOFFALOB_01254 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
DOFFALOB_01255 2.4e-186 pksD Q Acyl transferase domain
DOFFALOB_01256 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
DOFFALOB_01257 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
DOFFALOB_01258 4.4e-109 pksA K Transcriptional regulator
DOFFALOB_01259 1.2e-97 ymcC S Membrane
DOFFALOB_01261 2.3e-70 S Regulatory protein YrvL
DOFFALOB_01262 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DOFFALOB_01263 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DOFFALOB_01264 2.2e-88 cotE S Spore coat protein
DOFFALOB_01265 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
DOFFALOB_01266 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DOFFALOB_01267 6.5e-218 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
DOFFALOB_01268 2.7e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
DOFFALOB_01269 1.2e-36 spoVS S Stage V sporulation protein S
DOFFALOB_01270 1.9e-152 ymdB S protein conserved in bacteria
DOFFALOB_01271 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
DOFFALOB_01272 1e-215 pbpX V Beta-lactamase
DOFFALOB_01273 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DOFFALOB_01274 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
DOFFALOB_01275 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DOFFALOB_01276 1.9e-124 ymfM S protein conserved in bacteria
DOFFALOB_01277 2.7e-143 ymfK S Protein of unknown function (DUF3388)
DOFFALOB_01278 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
DOFFALOB_01279 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
DOFFALOB_01280 1.4e-242 ymfH S zinc protease
DOFFALOB_01281 2.9e-235 ymfF S Peptidase M16
DOFFALOB_01282 1.5e-206 ymfD EGP Major facilitator Superfamily
DOFFALOB_01283 1.4e-133 ymfC K Transcriptional regulator
DOFFALOB_01284 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
DOFFALOB_01285 4.4e-32 S YlzJ-like protein
DOFFALOB_01286 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
DOFFALOB_01287 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DOFFALOB_01288 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DOFFALOB_01289 5.9e-222 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
DOFFALOB_01290 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DOFFALOB_01291 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
DOFFALOB_01292 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
DOFFALOB_01293 2.6e-42 ymxH S YlmC YmxH family
DOFFALOB_01294 4.4e-233 pepR S Belongs to the peptidase M16 family
DOFFALOB_01295 4.2e-183 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
DOFFALOB_01296 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
DOFFALOB_01297 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DOFFALOB_01298 6.1e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
DOFFALOB_01299 1.3e-173 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DOFFALOB_01300 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DOFFALOB_01301 3e-44 ylxP S protein conserved in bacteria
DOFFALOB_01302 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DOFFALOB_01303 3.1e-47 ylxQ J ribosomal protein
DOFFALOB_01304 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
DOFFALOB_01305 1.1e-203 nusA K Participates in both transcription termination and antitermination
DOFFALOB_01306 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
DOFFALOB_01307 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DOFFALOB_01308 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DOFFALOB_01309 7.7e-233 rasP M zinc metalloprotease
DOFFALOB_01310 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
DOFFALOB_01311 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
DOFFALOB_01312 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DOFFALOB_01313 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DOFFALOB_01314 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
DOFFALOB_01315 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DOFFALOB_01316 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
DOFFALOB_01317 4.3e-78 ylxL
DOFFALOB_01318 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DOFFALOB_01319 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
DOFFALOB_01320 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
DOFFALOB_01321 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
DOFFALOB_01322 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
DOFFALOB_01323 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
DOFFALOB_01324 7.5e-158 flhG D Belongs to the ParA family
DOFFALOB_01325 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
DOFFALOB_01326 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DOFFALOB_01327 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DOFFALOB_01328 3.6e-132 fliR N Flagellar biosynthetic protein FliR
DOFFALOB_01329 2.2e-36 fliQ N Role in flagellar biosynthesis
DOFFALOB_01330 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
DOFFALOB_01331 9.3e-97 fliZ N Flagellar biosynthesis protein, FliO
DOFFALOB_01332 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
DOFFALOB_01333 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DOFFALOB_01334 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
DOFFALOB_01335 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
DOFFALOB_01336 8.2e-140 flgG N Flagellar basal body rod
DOFFALOB_01337 1.7e-72 flgD N Flagellar basal body rod modification protein
DOFFALOB_01338 1.2e-221 fliK N Flagellar hook-length control protein
DOFFALOB_01339 7.7e-37 ylxF S MgtE intracellular N domain
DOFFALOB_01340 1.5e-69 fliJ N Flagellar biosynthesis chaperone
DOFFALOB_01341 2.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
DOFFALOB_01342 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
DOFFALOB_01343 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
DOFFALOB_01344 2.4e-255 fliF N The M ring may be actively involved in energy transduction
DOFFALOB_01345 1.9e-31 fliE N Flagellar hook-basal body
DOFFALOB_01346 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
DOFFALOB_01347 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
DOFFALOB_01348 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DOFFALOB_01349 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DOFFALOB_01350 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DOFFALOB_01351 2.5e-169 xerC L tyrosine recombinase XerC
DOFFALOB_01352 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DOFFALOB_01353 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DOFFALOB_01354 1.7e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
DOFFALOB_01355 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DOFFALOB_01356 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
DOFFALOB_01357 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
DOFFALOB_01358 8.5e-291 ylqG
DOFFALOB_01359 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DOFFALOB_01360 4.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DOFFALOB_01361 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DOFFALOB_01362 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
DOFFALOB_01363 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DOFFALOB_01364 1.3e-61 ylqD S YlqD protein
DOFFALOB_01365 1.2e-36 ylqC S Belongs to the UPF0109 family
DOFFALOB_01366 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
DOFFALOB_01367 6e-236 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DOFFALOB_01368 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DOFFALOB_01369 2.9e-87
DOFFALOB_01370 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DOFFALOB_01371 0.0 smc D Required for chromosome condensation and partitioning
DOFFALOB_01372 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DOFFALOB_01373 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
DOFFALOB_01374 6.1e-129 IQ reductase
DOFFALOB_01375 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
DOFFALOB_01376 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
DOFFALOB_01377 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
DOFFALOB_01378 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DOFFALOB_01379 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
DOFFALOB_01380 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
DOFFALOB_01381 2.7e-302 yloV S kinase related to dihydroxyacetone kinase
DOFFALOB_01382 5.5e-59 asp S protein conserved in bacteria
DOFFALOB_01383 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
DOFFALOB_01384 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
DOFFALOB_01385 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
DOFFALOB_01386 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
DOFFALOB_01387 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
DOFFALOB_01388 2.4e-141 stp 3.1.3.16 T phosphatase
DOFFALOB_01389 4.8e-207 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
DOFFALOB_01390 2.9e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DOFFALOB_01391 3.8e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DOFFALOB_01392 6e-85 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DOFFALOB_01393 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DOFFALOB_01394 8.8e-226 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DOFFALOB_01395 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
DOFFALOB_01396 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
DOFFALOB_01397 1.5e-40 ylzA S Belongs to the UPF0296 family
DOFFALOB_01398 2.4e-156 yloC S stress-induced protein
DOFFALOB_01399 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
DOFFALOB_01400 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
DOFFALOB_01401 4.3e-83 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
DOFFALOB_01402 2e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
DOFFALOB_01403 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
DOFFALOB_01404 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
DOFFALOB_01405 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
DOFFALOB_01406 1.1e-179 cysP P phosphate transporter
DOFFALOB_01407 3.5e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
DOFFALOB_01409 2.9e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DOFFALOB_01410 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
DOFFALOB_01411 2.9e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DOFFALOB_01412 4.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
DOFFALOB_01413 0.0 carB 6.3.5.5 F Belongs to the CarB family
DOFFALOB_01414 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
DOFFALOB_01415 1.7e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DOFFALOB_01416 1.4e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
DOFFALOB_01417 9e-232 pyrP F Xanthine uracil
DOFFALOB_01418 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DOFFALOB_01419 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DOFFALOB_01420 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DOFFALOB_01421 1.3e-63 dksA T COG1734 DnaK suppressor protein
DOFFALOB_01422 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DOFFALOB_01423 2.6e-67 divIVA D Cell division initiation protein
DOFFALOB_01424 6.7e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
DOFFALOB_01425 1.3e-39 yggT S membrane
DOFFALOB_01426 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
DOFFALOB_01427 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DOFFALOB_01428 1.1e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
DOFFALOB_01429 2.4e-37 ylmC S sporulation protein
DOFFALOB_01430 1.3e-256 argE 3.5.1.16 E Acetylornithine deacetylase
DOFFALOB_01431 1.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
DOFFALOB_01432 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DOFFALOB_01433 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DOFFALOB_01434 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
DOFFALOB_01435 0.0 bpr O COG1404 Subtilisin-like serine proteases
DOFFALOB_01436 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DOFFALOB_01437 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
DOFFALOB_01438 6.2e-58 sbp S small basic protein
DOFFALOB_01439 1e-102 ylxX S protein conserved in bacteria
DOFFALOB_01440 2.4e-103 ylxW S protein conserved in bacteria
DOFFALOB_01441 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
DOFFALOB_01442 5.3e-167 murB 1.3.1.98 M cell wall formation
DOFFALOB_01443 2.3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DOFFALOB_01444 5.7e-186 spoVE D Belongs to the SEDS family
DOFFALOB_01445 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DOFFALOB_01446 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DOFFALOB_01447 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DOFFALOB_01448 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
DOFFALOB_01449 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
DOFFALOB_01450 3.7e-44 ftsL D Essential cell division protein
DOFFALOB_01451 6.6e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DOFFALOB_01452 2.9e-78 mraZ K Belongs to the MraZ family
DOFFALOB_01453 2.9e-309 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
DOFFALOB_01454 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DOFFALOB_01455 4e-89 ylbP K n-acetyltransferase
DOFFALOB_01456 6.8e-75 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
DOFFALOB_01457 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
DOFFALOB_01458 1.3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
DOFFALOB_01460 2.8e-235 ylbM S Belongs to the UPF0348 family
DOFFALOB_01461 6.8e-187 ylbL T Belongs to the peptidase S16 family
DOFFALOB_01462 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
DOFFALOB_01463 3.8e-221 ylbJ S Sporulation integral membrane protein YlbJ
DOFFALOB_01464 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DOFFALOB_01465 1.9e-98 rsmD 2.1.1.171 L Methyltransferase
DOFFALOB_01466 7.5e-39 ylbG S UPF0298 protein
DOFFALOB_01467 1.8e-75 ylbF S Belongs to the UPF0342 family
DOFFALOB_01468 6.7e-37 ylbE S YlbE-like protein
DOFFALOB_01469 4.1e-63 ylbD S Putative coat protein
DOFFALOB_01470 3e-201 ylbC S protein with SCP PR1 domains
DOFFALOB_01471 2.6e-74 ylbB T COG0517 FOG CBS domain
DOFFALOB_01472 7e-62 ylbA S YugN-like family
DOFFALOB_01473 3e-167 ctaG S cytochrome c oxidase
DOFFALOB_01474 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
DOFFALOB_01475 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
DOFFALOB_01476 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DOFFALOB_01477 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
DOFFALOB_01478 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
DOFFALOB_01479 2.6e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
DOFFALOB_01480 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DOFFALOB_01481 4.5e-214 ftsW D Belongs to the SEDS family
DOFFALOB_01482 8.7e-44 ylaN S Belongs to the UPF0358 family
DOFFALOB_01483 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
DOFFALOB_01484 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DOFFALOB_01485 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
DOFFALOB_01486 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
DOFFALOB_01487 2.5e-32 ylaI S protein conserved in bacteria
DOFFALOB_01488 4.2e-47 ylaH S YlaH-like protein
DOFFALOB_01489 0.0 typA T GTP-binding protein TypA
DOFFALOB_01490 8.2e-22 S Family of unknown function (DUF5325)
DOFFALOB_01491 1.8e-38 ylaE
DOFFALOB_01492 1.2e-11 sigC S Putative zinc-finger
DOFFALOB_01493 2.7e-91 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
DOFFALOB_01494 2.7e-42 ylaB
DOFFALOB_01495 0.0 ylaA
DOFFALOB_01496 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
DOFFALOB_01497 6.5e-173 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DOFFALOB_01498 6.9e-78 ykzC S Acetyltransferase (GNAT) family
DOFFALOB_01499 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
DOFFALOB_01500 7.1e-26 ykzI
DOFFALOB_01501 7.1e-118 yktB S Belongs to the UPF0637 family
DOFFALOB_01502 1.6e-42 yktA S Belongs to the UPF0223 family
DOFFALOB_01503 3.5e-277 speA 4.1.1.19 E Arginine
DOFFALOB_01504 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
DOFFALOB_01505 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
DOFFALOB_01506 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
DOFFALOB_01507 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
DOFFALOB_01508 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
DOFFALOB_01509 2e-115 recN L Putative cell-wall binding lipoprotein
DOFFALOB_01511 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DOFFALOB_01512 1.4e-147 ykrA S hydrolases of the HAD superfamily
DOFFALOB_01513 8.2e-31 ykzG S Belongs to the UPF0356 family
DOFFALOB_01514 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DOFFALOB_01515 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DOFFALOB_01516 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
DOFFALOB_01517 1.6e-162 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
DOFFALOB_01518 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
DOFFALOB_01519 1.5e-43 abrB K of stationary sporulation gene expression
DOFFALOB_01520 7.7e-183 mreB D Rod-share determining protein MreBH
DOFFALOB_01521 1.1e-12 S Uncharacterized protein YkpC
DOFFALOB_01522 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
DOFFALOB_01523 1.5e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DOFFALOB_01524 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
DOFFALOB_01525 8.1e-39 ykoA
DOFFALOB_01526 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
DOFFALOB_01527 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
DOFFALOB_01528 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
DOFFALOB_01529 3.1e-136 fruR K Transcriptional regulator
DOFFALOB_01530 2.1e-211 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
DOFFALOB_01531 2.5e-124 macB V ABC transporter, ATP-binding protein
DOFFALOB_01532 3e-159 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DOFFALOB_01533 1e-117 yknW S Yip1 domain
DOFFALOB_01534 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
DOFFALOB_01535 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
DOFFALOB_01536 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DOFFALOB_01537 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
DOFFALOB_01538 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
DOFFALOB_01539 8.1e-246 moeA 2.10.1.1 H molybdopterin
DOFFALOB_01540 5.3e-192 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
DOFFALOB_01541 3.9e-110 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
DOFFALOB_01542 2.9e-147 yknT
DOFFALOB_01543 5.8e-95 rok K Repressor of ComK
DOFFALOB_01544 4.4e-82 ykuV CO thiol-disulfide
DOFFALOB_01545 3.9e-101 ykuU O Alkyl hydroperoxide reductase
DOFFALOB_01546 8.8e-142 ykuT M Mechanosensitive ion channel
DOFFALOB_01547 9e-37 ykuS S Belongs to the UPF0180 family
DOFFALOB_01548 5.8e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
DOFFALOB_01549 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
DOFFALOB_01550 3.2e-80 fld C Flavodoxin
DOFFALOB_01551 3.2e-177 ykuO
DOFFALOB_01552 5.7e-88 fld C Flavodoxin domain
DOFFALOB_01553 3.5e-168 ccpC K Transcriptional regulator
DOFFALOB_01554 1.6e-76 ykuL S CBS domain
DOFFALOB_01555 3.9e-27 ykzF S Antirepressor AbbA
DOFFALOB_01556 4.4e-94 ykuK S Ribonuclease H-like
DOFFALOB_01557 3.9e-37 ykuJ S protein conserved in bacteria
DOFFALOB_01558 5.2e-234 ykuI T Diguanylate phosphodiesterase
DOFFALOB_01560 1.7e-93 M Peptidoglycan-binding domain 1 protein
DOFFALOB_01561 0.0 3.2.1.132 M Putative peptidoglycan binding domain
DOFFALOB_01562 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DOFFALOB_01563 9.4e-166 ykuE S Metallophosphoesterase
DOFFALOB_01564 4.6e-88 ykuD S protein conserved in bacteria
DOFFALOB_01565 1.6e-238 ykuC EGP Major facilitator Superfamily
DOFFALOB_01566 1.7e-84 ykyB S YkyB-like protein
DOFFALOB_01567 1.6e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
DOFFALOB_01568 2.2e-15
DOFFALOB_01569 8e-224 patA 2.6.1.1 E Aminotransferase
DOFFALOB_01570 0.0 pilS 2.7.13.3 T Histidine kinase
DOFFALOB_01571 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
DOFFALOB_01572 8e-124 ykwD J protein with SCP PR1 domains
DOFFALOB_01573 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
DOFFALOB_01574 2e-264 mcpC NT chemotaxis protein
DOFFALOB_01575 1.2e-131 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DOFFALOB_01576 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
DOFFALOB_01577 7.2e-39 splA S Transcriptional regulator
DOFFALOB_01578 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DOFFALOB_01579 2.1e-39 ptsH G phosphocarrier protein HPr
DOFFALOB_01580 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
DOFFALOB_01581 4.5e-128 glcT K antiterminator
DOFFALOB_01583 9.8e-180 ykvZ 5.1.1.1 K Transcriptional regulator
DOFFALOB_01585 8.7e-209 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
DOFFALOB_01586 3.8e-09
DOFFALOB_01587 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
DOFFALOB_01588 4.9e-90 stoA CO thiol-disulfide
DOFFALOB_01589 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
DOFFALOB_01590 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
DOFFALOB_01591 2.8e-28
DOFFALOB_01592 6e-25 ykvS S protein conserved in bacteria
DOFFALOB_01593 5.6e-46 ykvR S Protein of unknown function (DUF3219)
DOFFALOB_01594 8.5e-133 G Glycosyl hydrolases family 18
DOFFALOB_01595 1.2e-35 3.5.1.104 M LysM domain
DOFFALOB_01596 4e-217 ykvP 3.5.1.28 M Glycosyl transferases group 1
DOFFALOB_01597 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
DOFFALOB_01598 2e-61 ykvN K Transcriptional regulator
DOFFALOB_01599 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DOFFALOB_01600 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
DOFFALOB_01601 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
DOFFALOB_01602 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DOFFALOB_01603 8.7e-182 ykvI S membrane
DOFFALOB_01604 0.0 clpE O Belongs to the ClpA ClpB family
DOFFALOB_01605 2.7e-138 motA N flagellar motor
DOFFALOB_01606 2.5e-125 motB N Flagellar motor protein
DOFFALOB_01607 1.3e-75 ykvE K transcriptional
DOFFALOB_01608 2.5e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
DOFFALOB_01609 1.4e-64 eag
DOFFALOB_01610 6.4e-09 S Spo0E like sporulation regulatory protein
DOFFALOB_01611 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
DOFFALOB_01612 1.3e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
DOFFALOB_01613 7.2e-115 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
DOFFALOB_01614 7.5e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
DOFFALOB_01615 4.1e-231 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
DOFFALOB_01616 8e-232 mtnE 2.6.1.83 E Aminotransferase
DOFFALOB_01617 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
DOFFALOB_01618 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
DOFFALOB_01619 3.3e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DOFFALOB_01621 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DOFFALOB_01622 0.0 kinE 2.7.13.3 T Histidine kinase
DOFFALOB_01623 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
DOFFALOB_01624 4.5e-22 ykzE
DOFFALOB_01625 1.2e-10 ydfR S Protein of unknown function (DUF421)
DOFFALOB_01626 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
DOFFALOB_01627 7e-156 htpX O Belongs to the peptidase M48B family
DOFFALOB_01628 1.5e-124 ykrK S Domain of unknown function (DUF1836)
DOFFALOB_01629 1.9e-26 sspD S small acid-soluble spore protein
DOFFALOB_01630 8.2e-117 rsgI S Anti-sigma factor N-terminus
DOFFALOB_01631 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DOFFALOB_01632 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
DOFFALOB_01633 1.4e-116 ykoX S membrane-associated protein
DOFFALOB_01634 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
DOFFALOB_01635 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DOFFALOB_01636 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
DOFFALOB_01637 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
DOFFALOB_01638 0.0 ykoS
DOFFALOB_01639 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
DOFFALOB_01640 3.7e-99 ykoP G polysaccharide deacetylase
DOFFALOB_01641 2.3e-220 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
DOFFALOB_01642 1.3e-81 mhqR K transcriptional
DOFFALOB_01643 6.9e-26 ykoL
DOFFALOB_01644 5.9e-18
DOFFALOB_01645 1.4e-53 tnrA K transcriptional
DOFFALOB_01646 2.2e-222 mgtE P Acts as a magnesium transporter
DOFFALOB_01649 4.4e-86 ykoJ S Peptidase propeptide and YPEB domain
DOFFALOB_01650 1.1e-113 ykoI S Peptidase propeptide and YPEB domain
DOFFALOB_01651 9.4e-245 ykoH 2.7.13.3 T Histidine kinase
DOFFALOB_01652 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DOFFALOB_01653 7.9e-111 ykoF S YKOF-related Family
DOFFALOB_01654 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
DOFFALOB_01655 4.6e-311 P ABC transporter, ATP-binding protein
DOFFALOB_01656 1.8e-136 ykoC P Cobalt transport protein
DOFFALOB_01657 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
DOFFALOB_01658 1.7e-176 isp O Belongs to the peptidase S8 family
DOFFALOB_01659 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DOFFALOB_01660 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
DOFFALOB_01662 8.4e-72 ohrB O Organic hydroperoxide resistance protein
DOFFALOB_01663 3.9e-75 ohrR K COG1846 Transcriptional regulators
DOFFALOB_01664 1.3e-70 ohrA O Organic hydroperoxide resistance protein
DOFFALOB_01665 2.5e-228 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DOFFALOB_01666 1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DOFFALOB_01667 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
DOFFALOB_01668 1.1e-50 ykkD P Multidrug resistance protein
DOFFALOB_01669 3.5e-55 ykkC P Multidrug resistance protein
DOFFALOB_01670 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
DOFFALOB_01671 1e-98 ykkA S Protein of unknown function (DUF664)
DOFFALOB_01672 5.4e-130 ykjA S Protein of unknown function (DUF421)
DOFFALOB_01673 1e-07
DOFFALOB_01674 1e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DOFFALOB_01675 1.5e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
DOFFALOB_01676 5.3e-161 ykgA E Amidinotransferase
DOFFALOB_01677 7.4e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
DOFFALOB_01678 7.7e-188 ykfD E Belongs to the ABC transporter superfamily
DOFFALOB_01679 5.3e-172 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
DOFFALOB_01680 3.2e-203 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
DOFFALOB_01681 8.1e-179 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
DOFFALOB_01683 0.0 dppE E ABC transporter substrate-binding protein
DOFFALOB_01684 3.4e-191 dppD P Belongs to the ABC transporter superfamily
DOFFALOB_01685 3.9e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DOFFALOB_01686 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DOFFALOB_01687 7.9e-154 dppA E D-aminopeptidase
DOFFALOB_01688 1e-137 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
DOFFALOB_01689 8.5e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DOFFALOB_01691 1.3e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
DOFFALOB_01692 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DOFFALOB_01694 7.2e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
DOFFALOB_01695 9.4e-242 steT E amino acid
DOFFALOB_01696 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
DOFFALOB_01697 5.8e-175 pit P phosphate transporter
DOFFALOB_01698 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
DOFFALOB_01699 6.7e-23 spoIISB S Stage II sporulation protein SB
DOFFALOB_01700 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
DOFFALOB_01701 9.3e-40 xhlB S SPP1 phage holin
DOFFALOB_01702 2.8e-39 xhlA S Haemolysin XhlA
DOFFALOB_01703 1.2e-154 xepA
DOFFALOB_01704 1.7e-23 xkdX
DOFFALOB_01705 2.6e-55 xkdW S XkdW protein
DOFFALOB_01706 0.0
DOFFALOB_01707 6.7e-41
DOFFALOB_01708 4e-104 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
DOFFALOB_01709 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
DOFFALOB_01710 9.6e-71 xkdS S Protein of unknown function (DUF2634)
DOFFALOB_01711 2.1e-39 xkdR S Protein of unknown function (DUF2577)
DOFFALOB_01712 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
DOFFALOB_01713 3.7e-122 xkdP S Lysin motif
DOFFALOB_01714 0.0 xkdO L Transglycosylase SLT domain
DOFFALOB_01715 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
DOFFALOB_01716 6.1e-76 xkdM S Phage tail tube protein
DOFFALOB_01717 2.5e-256 xkdK S Phage tail sheath C-terminal domain
DOFFALOB_01718 1.9e-77 xkdJ
DOFFALOB_01719 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
DOFFALOB_01720 8.7e-65 yqbH S Domain of unknown function (DUF3599)
DOFFALOB_01721 5.5e-65 yqbG S Protein of unknown function (DUF3199)
DOFFALOB_01722 5.8e-169 xkdG S Phage capsid family
DOFFALOB_01723 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
DOFFALOB_01724 5.4e-286 yqbA S portal protein
DOFFALOB_01725 9.6e-255 xtmB S phage terminase, large subunit
DOFFALOB_01726 4.8e-140 xtmA L phage terminase small subunit
DOFFALOB_01727 4.4e-86 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
DOFFALOB_01728 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
DOFFALOB_01731 6.4e-119 xkdC L Bacterial dnaA protein
DOFFALOB_01732 5.9e-157 xkdB K sequence-specific DNA binding
DOFFALOB_01734 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
DOFFALOB_01735 1.6e-111 xkdA E IrrE N-terminal-like domain
DOFFALOB_01736 4.4e-160 ydbD P Catalase
DOFFALOB_01737 4.2e-112 yjqB S Pfam:DUF867
DOFFALOB_01738 2.1e-61 yjqA S Bacterial PH domain
DOFFALOB_01739 9.1e-170 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
DOFFALOB_01740 6.3e-41 S YCII-related domain
DOFFALOB_01742 2.1e-213 S response regulator aspartate phosphatase
DOFFALOB_01743 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
DOFFALOB_01744 3.3e-80 yjoA S DinB family
DOFFALOB_01745 4.3e-130 MA20_18170 S membrane transporter protein
DOFFALOB_01746 2e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
DOFFALOB_01747 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
DOFFALOB_01748 2.3e-184 exuR K transcriptional
DOFFALOB_01749 3.7e-227 exuT G Sugar (and other) transporter
DOFFALOB_01750 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
DOFFALOB_01751 4.7e-215 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
DOFFALOB_01752 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
DOFFALOB_01753 3e-195 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
DOFFALOB_01754 5.8e-250 yjmB G symporter YjmB
DOFFALOB_01755 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
DOFFALOB_01756 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
DOFFALOB_01757 7.1e-66 yjlC S Protein of unknown function (DUF1641)
DOFFALOB_01758 2.8e-93 yjlB S Cupin domain
DOFFALOB_01759 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
DOFFALOB_01760 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
DOFFALOB_01761 1.9e-122 ybbM S transport system, permease component
DOFFALOB_01762 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
DOFFALOB_01763 8.2e-30
DOFFALOB_01764 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
DOFFALOB_01765 3.8e-226 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
DOFFALOB_01767 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
DOFFALOB_01768 8.7e-07 S Domain of unknown function (DUF4352)
DOFFALOB_01769 4.3e-95 yjgD S Protein of unknown function (DUF1641)
DOFFALOB_01770 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
DOFFALOB_01771 8.9e-104 yjgB S Domain of unknown function (DUF4309)
DOFFALOB_01772 1.2e-45 T PhoQ Sensor
DOFFALOB_01773 1.6e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
DOFFALOB_01774 3.6e-21 yjfB S Putative motility protein
DOFFALOB_01775 5.5e-83 S Protein of unknown function (DUF2690)
DOFFALOB_01776 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
DOFFALOB_01778 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
DOFFALOB_01779 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
DOFFALOB_01780 4.2e-29 S Domain of unknown function (DUF4177)
DOFFALOB_01781 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DOFFALOB_01783 2.5e-94 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
DOFFALOB_01784 4.8e-51 yjdF S Protein of unknown function (DUF2992)
DOFFALOB_01785 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
DOFFALOB_01786 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
DOFFALOB_01787 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
DOFFALOB_01789 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
DOFFALOB_01790 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
DOFFALOB_01791 1.1e-92 yqaS L DNA packaging
DOFFALOB_01792 4.1e-49 S YjcQ protein
DOFFALOB_01793 1.6e-72 yjcP
DOFFALOB_01794 8.5e-81 L Transposase
DOFFALOB_01797 2.6e-44 yjcN
DOFFALOB_01798 2.1e-190 S Putative amidase domain
DOFFALOB_01801 1.1e-212 yjcL S Protein of unknown function (DUF819)
DOFFALOB_01802 3.7e-99 rimJ 2.3.1.128 J Alanine acetyltransferase
DOFFALOB_01803 2.9e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
DOFFALOB_01804 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
DOFFALOB_01805 1.8e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
DOFFALOB_01806 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
DOFFALOB_01807 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DOFFALOB_01808 1.7e-38
DOFFALOB_01809 0.0 yjcD 3.6.4.12 L DNA helicase
DOFFALOB_01810 2.9e-38 spoVIF S Stage VI sporulation protein F
DOFFALOB_01813 8.7e-57 yjcA S Protein of unknown function (DUF1360)
DOFFALOB_01814 2.3e-55 cotV S Spore Coat Protein X and V domain
DOFFALOB_01815 3e-32 cotW
DOFFALOB_01816 6.4e-77 cotX S Spore Coat Protein X and V domain
DOFFALOB_01817 3.4e-96 cotY S Spore coat protein Z
DOFFALOB_01818 5.2e-83 cotZ S Spore coat protein
DOFFALOB_01819 5.9e-54 yjbX S Spore coat protein
DOFFALOB_01820 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
DOFFALOB_01821 5.3e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
DOFFALOB_01822 6e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
DOFFALOB_01823 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
DOFFALOB_01824 3e-30 thiS H thiamine diphosphate biosynthetic process
DOFFALOB_01825 7.2e-219 thiO 1.4.3.19 E Glycine oxidase
DOFFALOB_01826 3.8e-108 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
DOFFALOB_01827 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DOFFALOB_01828 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
DOFFALOB_01829 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
DOFFALOB_01830 9.5e-161 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DOFFALOB_01831 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DOFFALOB_01832 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
DOFFALOB_01833 7.1e-62 yjbL S Belongs to the UPF0738 family
DOFFALOB_01834 2.4e-101 yjbK S protein conserved in bacteria
DOFFALOB_01835 1.5e-87 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
DOFFALOB_01836 3.7e-72 yjbI S Bacterial-like globin
DOFFALOB_01837 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
DOFFALOB_01839 1.8e-20
DOFFALOB_01840 0.0 pepF E oligoendopeptidase F
DOFFALOB_01841 2.3e-223 yjbF S Competence protein
DOFFALOB_01842 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
DOFFALOB_01843 6e-112 yjbE P Integral membrane protein TerC family
DOFFALOB_01844 2.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
DOFFALOB_01845 6.9e-104 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DOFFALOB_01846 8.6e-196 yjbB EGP Major Facilitator Superfamily
DOFFALOB_01847 5.5e-172 oppF E Belongs to the ABC transporter superfamily
DOFFALOB_01848 3e-198 oppD P Belongs to the ABC transporter superfamily
DOFFALOB_01849 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DOFFALOB_01850 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DOFFALOB_01851 0.0 oppA E ABC transporter substrate-binding protein
DOFFALOB_01852 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
DOFFALOB_01853 5e-147 yjbA S Belongs to the UPF0736 family
DOFFALOB_01854 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DOFFALOB_01855 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DOFFALOB_01856 1.6e-251 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
DOFFALOB_01857 6.5e-187 appF E Belongs to the ABC transporter superfamily
DOFFALOB_01858 1.8e-184 appD P Belongs to the ABC transporter superfamily
DOFFALOB_01859 7.8e-151 yjaZ O Zn-dependent protease
DOFFALOB_01860 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
DOFFALOB_01861 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DOFFALOB_01862 2.7e-22 yjzB
DOFFALOB_01863 7.3e-26 comZ S ComZ
DOFFALOB_01864 1.1e-183 med S Transcriptional activator protein med
DOFFALOB_01865 7.3e-103 yjaV
DOFFALOB_01866 6.2e-142 yjaU I carboxylic ester hydrolase activity
DOFFALOB_01867 2.3e-16 yjzD S Protein of unknown function (DUF2929)
DOFFALOB_01868 9.5e-28 yjzC S YjzC-like protein
DOFFALOB_01869 3.8e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DOFFALOB_01870 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
DOFFALOB_01871 3.9e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
DOFFALOB_01872 4.4e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
DOFFALOB_01873 2.2e-137 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
DOFFALOB_01874 3.1e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DOFFALOB_01875 5.4e-200 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DOFFALOB_01876 1.7e-88 norB G Major Facilitator Superfamily
DOFFALOB_01877 4.3e-272 yitY C D-arabinono-1,4-lactone oxidase
DOFFALOB_01878 1.5e-22 pilT S Proteolipid membrane potential modulator
DOFFALOB_01879 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
DOFFALOB_01880 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
DOFFALOB_01881 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
DOFFALOB_01882 1.2e-17 S Protein of unknown function (DUF3813)
DOFFALOB_01883 1.9e-72 ipi S Intracellular proteinase inhibitor
DOFFALOB_01884 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
DOFFALOB_01885 8.4e-159 yitS S protein conserved in bacteria
DOFFALOB_01886 2.2e-311 nprB 3.4.24.28 E Peptidase M4
DOFFALOB_01887 1.4e-44 yitR S Domain of unknown function (DUF3784)
DOFFALOB_01888 2e-95
DOFFALOB_01889 1.5e-58 K Transcriptional regulator PadR-like family
DOFFALOB_01890 1.5e-97 S Sporulation delaying protein SdpA
DOFFALOB_01891 2.8e-171
DOFFALOB_01892 8.5e-94
DOFFALOB_01893 4e-161 cvfB S protein conserved in bacteria
DOFFALOB_01894 8.6e-55 yajQ S Belongs to the UPF0234 family
DOFFALOB_01895 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
DOFFALOB_01896 5.8e-82 yjcF S Acetyltransferase (GNAT) domain
DOFFALOB_01897 1.8e-161 yitH K Acetyltransferase (GNAT) domain
DOFFALOB_01898 4e-229 yitG EGP Major facilitator Superfamily
DOFFALOB_01899 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
DOFFALOB_01900 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
DOFFALOB_01901 1.9e-141 yitD 4.4.1.19 S synthase
DOFFALOB_01902 4.9e-125 comB 3.1.3.71 H Belongs to the ComB family
DOFFALOB_01903 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
DOFFALOB_01904 3.2e-233 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
DOFFALOB_01905 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
DOFFALOB_01906 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
DOFFALOB_01907 4e-36 mcbG S Pentapeptide repeats (9 copies)
DOFFALOB_01908 1.7e-281 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
DOFFALOB_01909 6.4e-108 argO S Lysine exporter protein LysE YggA
DOFFALOB_01910 1.3e-93 yisT S DinB family
DOFFALOB_01911 4.5e-199 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
DOFFALOB_01912 2.4e-184 purR K helix_turn _helix lactose operon repressor
DOFFALOB_01913 1.2e-160 yisR K Transcriptional regulator
DOFFALOB_01914 4e-243 yisQ V Mate efflux family protein
DOFFALOB_01915 6.8e-150 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
DOFFALOB_01916 2.1e-88 yizA S Damage-inducible protein DinB
DOFFALOB_01917 0.0 asnO 6.3.5.4 E Asparagine synthase
DOFFALOB_01918 7.2e-106 yisN S Protein of unknown function (DUF2777)
DOFFALOB_01919 0.0 wprA O Belongs to the peptidase S8 family
DOFFALOB_01920 3e-57 yisL S UPF0344 protein
DOFFALOB_01921 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
DOFFALOB_01922 1.7e-176 cotH M Spore Coat
DOFFALOB_01923 1.5e-22 yisI S Spo0E like sporulation regulatory protein
DOFFALOB_01924 1.9e-33 gerPA S Spore germination protein
DOFFALOB_01925 4e-34 gerPB S cell differentiation
DOFFALOB_01926 1.8e-54 gerPC S Spore germination protein
DOFFALOB_01927 6.3e-24 gerPD S Spore germination protein
DOFFALOB_01928 3e-66 gerPE S Spore germination protein GerPE
DOFFALOB_01929 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
DOFFALOB_01930 6e-51 yisB V COG1403 Restriction endonuclease
DOFFALOB_01931 0.0 sbcC L COG0419 ATPase involved in DNA repair
DOFFALOB_01932 1.7e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
DOFFALOB_01933 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
DOFFALOB_01934 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
DOFFALOB_01935 2.2e-78 yhjR S Rubrerythrin
DOFFALOB_01936 2e-36 yhjQ C COG1145 Ferredoxin
DOFFALOB_01937 0.0 S Sugar transport-related sRNA regulator N-term
DOFFALOB_01938 3.1e-215 EGP Transmembrane secretion effector
DOFFALOB_01939 3.8e-202 abrB S membrane
DOFFALOB_01940 1.6e-188 yhjM 5.1.1.1 K Transcriptional regulator
DOFFALOB_01941 4.4e-255 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
DOFFALOB_01942 1.8e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
DOFFALOB_01943 1.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
DOFFALOB_01944 6.9e-215 glcP G Major Facilitator Superfamily
DOFFALOB_01945 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
DOFFALOB_01946 1.1e-286 yhjG CH FAD binding domain
DOFFALOB_01947 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
DOFFALOB_01948 9.1e-110 yhjE S SNARE associated Golgi protein
DOFFALOB_01949 5e-60 yhjD
DOFFALOB_01950 6.9e-27 yhjC S Protein of unknown function (DUF3311)
DOFFALOB_01951 6.1e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DOFFALOB_01952 7.8e-42 yhjA S Excalibur calcium-binding domain
DOFFALOB_01953 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
DOFFALOB_01954 4.2e-109 comK K Competence transcription factor
DOFFALOB_01955 1.3e-32 yhzC S IDEAL
DOFFALOB_01956 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DOFFALOB_01957 1.1e-302 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
DOFFALOB_01958 1.7e-182 hemAT NT chemotaxis protein
DOFFALOB_01959 5e-91 bioY S BioY family
DOFFALOB_01960 1e-281 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
DOFFALOB_01961 2.3e-201 vraB 2.3.1.9 I Belongs to the thiolase family
DOFFALOB_01962 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
DOFFALOB_01963 4.3e-159 yfmC M Periplasmic binding protein
DOFFALOB_01964 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
DOFFALOB_01965 9.2e-80 VY92_01935 K acetyltransferase
DOFFALOB_01966 2.3e-204 aprE 3.4.21.62 O Belongs to the peptidase S8 family
DOFFALOB_01967 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
DOFFALOB_01968 1.9e-65 yhfM
DOFFALOB_01969 7.3e-302 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
DOFFALOB_01970 2.6e-112 yhfK GM NmrA-like family
DOFFALOB_01971 2e-191 lplJ 6.3.1.20 H Lipoate-protein ligase
DOFFALOB_01972 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
DOFFALOB_01973 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DOFFALOB_01974 1.7e-72 3.4.13.21 S ASCH
DOFFALOB_01975 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
DOFFALOB_01976 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
DOFFALOB_01977 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DOFFALOB_01978 1e-238 yhgE S YhgE Pip N-terminal domain protein
DOFFALOB_01979 1.4e-101 yhgD K Transcriptional regulator
DOFFALOB_01980 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DOFFALOB_01981 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
DOFFALOB_01982 1.7e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DOFFALOB_01983 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
DOFFALOB_01984 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
DOFFALOB_01985 7.5e-17 1.15.1.2 C Rubrerythrin
DOFFALOB_01986 4.2e-248 yhfA C membrane
DOFFALOB_01987 2.3e-231 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
DOFFALOB_01988 4.8e-115 ecsC S EcsC protein family
DOFFALOB_01989 1.8e-215 ecsB U ABC transporter
DOFFALOB_01990 4.6e-137 ecsA V transporter (ATP-binding protein)
DOFFALOB_01991 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
DOFFALOB_01992 9.9e-205 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DOFFALOB_01993 3.6e-80 trpP S Tryptophan transporter TrpP
DOFFALOB_01994 7e-39 yhaH S YtxH-like protein
DOFFALOB_01995 1e-113 hpr K Negative regulator of protease production and sporulation
DOFFALOB_01996 1.3e-54 yhaI S Protein of unknown function (DUF1878)
DOFFALOB_01997 8.7e-90 yhaK S Putative zincin peptidase
DOFFALOB_01998 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
DOFFALOB_01999 1.6e-21 yhaL S Sporulation protein YhaL
DOFFALOB_02000 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
DOFFALOB_02001 0.0 yhaN L AAA domain
DOFFALOB_02002 3.6e-227 yhaO L DNA repair exonuclease
DOFFALOB_02003 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
DOFFALOB_02004 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
DOFFALOB_02005 1.1e-26 S YhzD-like protein
DOFFALOB_02006 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
DOFFALOB_02008 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
DOFFALOB_02009 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
DOFFALOB_02010 7.1e-294 hemZ H coproporphyrinogen III oxidase
DOFFALOB_02011 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
DOFFALOB_02012 3.1e-206 yhaZ L DNA alkylation repair enzyme
DOFFALOB_02013 9.5e-48 yheA S Belongs to the UPF0342 family
DOFFALOB_02014 6.7e-204 yheB S Belongs to the UPF0754 family
DOFFALOB_02015 4.3e-216 yheC HJ YheC/D like ATP-grasp
DOFFALOB_02016 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
DOFFALOB_02017 1.3e-36 yheE S Family of unknown function (DUF5342)
DOFFALOB_02018 6.3e-28 sspB S spore protein
DOFFALOB_02019 3.7e-111 yheG GM NAD(P)H-binding
DOFFALOB_02020 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
DOFFALOB_02021 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
DOFFALOB_02022 3.4e-84 nhaX T Belongs to the universal stress protein A family
DOFFALOB_02023 2.2e-233 nhaC C Na H antiporter
DOFFALOB_02024 1.1e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
DOFFALOB_02025 1.7e-151 yheN G deacetylase
DOFFALOB_02026 1.2e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
DOFFALOB_02027 6.6e-204 yhdY M Mechanosensitive ion channel
DOFFALOB_02029 3.3e-135 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
DOFFALOB_02030 5.1e-66 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DOFFALOB_02031 2.8e-47 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DOFFALOB_02032 1.1e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
DOFFALOB_02033 1.4e-223 yhdR 2.6.1.1 E Aminotransferase
DOFFALOB_02034 4.1e-74 cueR K transcriptional
DOFFALOB_02035 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
DOFFALOB_02036 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
DOFFALOB_02037 1.5e-191 yhdN C Aldo keto reductase
DOFFALOB_02038 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
DOFFALOB_02039 6.6e-201 yhdL S Sigma factor regulator N-terminal
DOFFALOB_02040 8.1e-45 yhdK S Sigma-M inhibitor protein
DOFFALOB_02041 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DOFFALOB_02042 3.7e-276 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
DOFFALOB_02043 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
DOFFALOB_02044 3.4e-250 yhdG E amino acid
DOFFALOB_02045 4.9e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DOFFALOB_02046 1.4e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
DOFFALOB_02047 3.8e-162 citR K Transcriptional regulator
DOFFALOB_02048 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
DOFFALOB_02049 5.8e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
DOFFALOB_02050 2.1e-276 ycgB S Stage V sporulation protein R
DOFFALOB_02051 8.7e-239 ygxB M Conserved TM helix
DOFFALOB_02052 3.5e-76 nsrR K Transcriptional regulator
DOFFALOB_02053 7.9e-189 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
DOFFALOB_02054 4.8e-54 yhdC S Protein of unknown function (DUF3889)
DOFFALOB_02055 1.2e-38 yhdB S YhdB-like protein
DOFFALOB_02056 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
DOFFALOB_02057 1.1e-113 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DOFFALOB_02058 5.5e-214 yhcY 2.7.13.3 T Histidine kinase
DOFFALOB_02059 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
DOFFALOB_02060 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DOFFALOB_02061 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DOFFALOB_02062 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
DOFFALOB_02063 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DOFFALOB_02064 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DOFFALOB_02065 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
DOFFALOB_02066 4.6e-120 yhcW 5.4.2.6 S hydrolase
DOFFALOB_02067 9.9e-68 yhcV S COG0517 FOG CBS domain
DOFFALOB_02068 9.3e-68 yhcU S Family of unknown function (DUF5365)
DOFFALOB_02069 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DOFFALOB_02070 7.6e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
DOFFALOB_02071 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
DOFFALOB_02072 5.2e-100 yhcQ M Spore coat protein
DOFFALOB_02073 2.5e-167 yhcP
DOFFALOB_02074 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
DOFFALOB_02075 3.7e-44 yhcM
DOFFALOB_02076 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DOFFALOB_02077 1.2e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
DOFFALOB_02078 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
DOFFALOB_02079 1e-30 cspB K Cold-shock protein
DOFFALOB_02080 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
DOFFALOB_02081 2.6e-166 yhcH V ABC transporter, ATP-binding protein
DOFFALOB_02082 1.6e-123 yhcG V ABC transporter, ATP-binding protein
DOFFALOB_02083 6.6e-60 yhcF K Transcriptional regulator
DOFFALOB_02084 7.8e-55
DOFFALOB_02085 2.8e-37 yhcC
DOFFALOB_02086 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
DOFFALOB_02087 3.1e-271 yhcA EGP Major facilitator Superfamily
DOFFALOB_02088 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
DOFFALOB_02089 2.2e-76 yhbI K DNA-binding transcription factor activity
DOFFALOB_02090 2.5e-225 yhbH S Belongs to the UPF0229 family
DOFFALOB_02091 0.0 prkA T Ser protein kinase
DOFFALOB_02092 8.2e-75 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
DOFFALOB_02093 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
DOFFALOB_02094 1.2e-109 yhbD K Protein of unknown function (DUF4004)
DOFFALOB_02095 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DOFFALOB_02096 4.4e-177 yhbB S Putative amidase domain
DOFFALOB_02097 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DOFFALOB_02098 3.9e-113 yhzB S B3/4 domain
DOFFALOB_02100 4.4e-29 K Transcriptional regulator
DOFFALOB_02101 4.1e-78 ygaO
DOFFALOB_02102 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DOFFALOB_02104 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
DOFFALOB_02105 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
DOFFALOB_02106 1.7e-171 ssuA M Sulfonate ABC transporter
DOFFALOB_02107 1.3e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
DOFFALOB_02108 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
DOFFALOB_02110 1.9e-266 ygaK C Berberine and berberine like
DOFFALOB_02111 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DOFFALOB_02112 5.9e-134 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
DOFFALOB_02113 3e-27
DOFFALOB_02114 2.7e-143 spo0M S COG4326 Sporulation control protein
DOFFALOB_02118 2e-08
DOFFALOB_02126 7.8e-08
DOFFALOB_02131 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
DOFFALOB_02132 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
DOFFALOB_02133 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
DOFFALOB_02134 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
DOFFALOB_02135 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
DOFFALOB_02137 0.0 htpG O Molecular chaperone. Has ATPase activity
DOFFALOB_02138 2.3e-246 csbC EGP Major facilitator Superfamily
DOFFALOB_02139 8.3e-48 yxcD S Protein of unknown function (DUF2653)
DOFFALOB_02141 3.7e-176 iolS C Aldo keto reductase
DOFFALOB_02142 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
DOFFALOB_02143 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
DOFFALOB_02144 1.1e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
DOFFALOB_02145 2.9e-179 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
DOFFALOB_02146 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
DOFFALOB_02147 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
DOFFALOB_02148 1.3e-235 iolF EGP Major facilitator Superfamily
DOFFALOB_02149 1.4e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
DOFFALOB_02150 8.6e-167 iolH G Xylose isomerase-like TIM barrel
DOFFALOB_02151 1.2e-138 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
DOFFALOB_02152 5.4e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
DOFFALOB_02153 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DOFFALOB_02154 1.3e-182 T PhoQ Sensor
DOFFALOB_02155 9.4e-141 yxdL V ABC transporter, ATP-binding protein
DOFFALOB_02156 0.0 yxdM V ABC transporter (permease)
DOFFALOB_02157 1.5e-58 yxeA S Protein of unknown function (DUF1093)
DOFFALOB_02158 6e-177 fhuD P ABC transporter
DOFFALOB_02159 8.5e-69
DOFFALOB_02160 1.9e-16 yxeD
DOFFALOB_02161 1.3e-20 yxeE
DOFFALOB_02164 6.2e-151 yidA S hydrolases of the HAD superfamily
DOFFALOB_02165 8.8e-192 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
DOFFALOB_02167 2.2e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DOFFALOB_02168 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DOFFALOB_02169 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
DOFFALOB_02170 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
DOFFALOB_02171 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
DOFFALOB_02172 3.8e-215 yxeP 3.5.1.47 E hydrolase activity
DOFFALOB_02173 2e-255 yxeQ S MmgE/PrpD family
DOFFALOB_02174 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
DOFFALOB_02175 3e-153 yxxB S Domain of Unknown Function (DUF1206)
DOFFALOB_02176 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
DOFFALOB_02177 7e-116 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DOFFALOB_02178 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DOFFALOB_02179 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
DOFFALOB_02180 3.4e-250 lysP E amino acid
DOFFALOB_02181 6.8e-181 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
DOFFALOB_02182 1.2e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
DOFFALOB_02183 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DOFFALOB_02184 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
DOFFALOB_02185 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
DOFFALOB_02186 6.3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
DOFFALOB_02187 2.1e-21 S Domain of unknown function (DUF5082)
DOFFALOB_02188 3.6e-39 yxiC S Family of unknown function (DUF5344)
DOFFALOB_02189 0.0 S nuclease activity
DOFFALOB_02190 2.2e-78 S SMI1 / KNR4 family
DOFFALOB_02191 3.6e-51
DOFFALOB_02192 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
DOFFALOB_02193 1.1e-280 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DOFFALOB_02194 1.1e-72 yxiE T Belongs to the universal stress protein A family
DOFFALOB_02195 2.9e-168 yxxF EG EamA-like transporter family
DOFFALOB_02196 0.0 wapA M COG3209 Rhs family protein
DOFFALOB_02197 1.5e-71 yxxG
DOFFALOB_02198 1.7e-84
DOFFALOB_02199 6.4e-63
DOFFALOB_02200 3.7e-75 yxiG
DOFFALOB_02201 4.9e-46
DOFFALOB_02202 3.8e-81
DOFFALOB_02203 1.2e-96 yxiI S Protein of unknown function (DUF2716)
DOFFALOB_02204 1.6e-48 yxiJ S YxiJ-like protein
DOFFALOB_02207 7.5e-219 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
DOFFALOB_02208 1e-265 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
DOFFALOB_02209 3e-232 yxiO S COG2270 Permeases of the major facilitator superfamily
DOFFALOB_02210 6.6e-114
DOFFALOB_02211 8.3e-151 licT K transcriptional antiterminator
DOFFALOB_02212 5e-144 exoK GH16 M licheninase activity
DOFFALOB_02213 6.6e-224 citH C Citrate transporter
DOFFALOB_02214 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
DOFFALOB_02215 2.7e-48 yxiS
DOFFALOB_02216 1.2e-22 T Domain of unknown function (DUF4163)
DOFFALOB_02217 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DOFFALOB_02218 2.2e-145 rlmA 2.1.1.187 Q Methyltransferase domain
DOFFALOB_02219 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
DOFFALOB_02220 1.4e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DOFFALOB_02221 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
DOFFALOB_02222 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
DOFFALOB_02223 1e-220 yxjG 2.1.1.14 E Methionine synthase
DOFFALOB_02224 5.5e-222 yxjG 2.1.1.14 E Methionine synthase
DOFFALOB_02225 1e-87 yxjI S LURP-one-related
DOFFALOB_02228 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
DOFFALOB_02229 8.9e-116 K helix_turn_helix, Lux Regulon
DOFFALOB_02230 1.5e-193 yxjM T Signal transduction histidine kinase
DOFFALOB_02231 2.4e-78 S Protein of unknown function (DUF1453)
DOFFALOB_02232 1.9e-166 yxjO K LysR substrate binding domain
DOFFALOB_02233 1.3e-95 yxkA S Phosphatidylethanolamine-binding protein
DOFFALOB_02234 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
DOFFALOB_02235 4.1e-73 yxkC S Domain of unknown function (DUF4352)
DOFFALOB_02236 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
DOFFALOB_02237 2.5e-275 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
DOFFALOB_02238 4.8e-165 lrp QT PucR C-terminal helix-turn-helix domain
DOFFALOB_02239 5.9e-205 msmK P Belongs to the ABC transporter superfamily
DOFFALOB_02240 3e-156 yxkH G Polysaccharide deacetylase
DOFFALOB_02242 0.0 3.4.24.84 O Peptidase family M48
DOFFALOB_02243 1.5e-229 cimH C COG3493 Na citrate symporter
DOFFALOB_02244 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
DOFFALOB_02245 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
DOFFALOB_02246 0.0 cydD V ATP-binding
DOFFALOB_02247 0.0 cydD V ATP-binding protein
DOFFALOB_02248 8e-162 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DOFFALOB_02249 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
DOFFALOB_02250 4.7e-91 sigY K Belongs to the sigma-70 factor family. ECF subfamily
DOFFALOB_02251 3.9e-48 yxlC S Family of unknown function (DUF5345)
DOFFALOB_02252 1.2e-31
DOFFALOB_02253 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
DOFFALOB_02254 5.1e-167 yxlF V ABC transporter, ATP-binding protein
DOFFALOB_02255 1.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
DOFFALOB_02256 5.3e-215 yxlH EGP Major facilitator Superfamily
DOFFALOB_02257 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
DOFFALOB_02258 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
DOFFALOB_02259 1.1e-19 yxzF
DOFFALOB_02260 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
DOFFALOB_02261 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
DOFFALOB_02262 7.4e-250 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DOFFALOB_02263 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
DOFFALOB_02264 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
DOFFALOB_02265 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
DOFFALOB_02266 6.6e-139 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
DOFFALOB_02267 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DOFFALOB_02268 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DOFFALOB_02269 1.2e-232 dltB M membrane protein involved in D-alanine export
DOFFALOB_02270 7.9e-293 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DOFFALOB_02271 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
DOFFALOB_02272 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
DOFFALOB_02273 1.4e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
DOFFALOB_02274 4.4e-233 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DOFFALOB_02275 8.1e-88 ywaE K Transcriptional regulator
DOFFALOB_02276 1.7e-128 ywaF S Integral membrane protein
DOFFALOB_02277 7e-169 gspA M General stress
DOFFALOB_02278 4e-153 sacY K transcriptional antiterminator
DOFFALOB_02279 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
DOFFALOB_02280 1.6e-277 epr 3.4.21.62 O Belongs to the peptidase S8 family
DOFFALOB_02281 5.8e-247 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DOFFALOB_02282 1.8e-127 ywbB S Protein of unknown function (DUF2711)
DOFFALOB_02283 4.4e-67 ywbC 4.4.1.5 E glyoxalase
DOFFALOB_02284 8.9e-223 ywbD 2.1.1.191 J Methyltransferase
DOFFALOB_02285 1.2e-28 ywbE S Uncharacterized conserved protein (DUF2196)
DOFFALOB_02286 1.9e-209 ywbF EGP Major facilitator Superfamily
DOFFALOB_02287 2.3e-111 ywbG M effector of murein hydrolase
DOFFALOB_02288 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
DOFFALOB_02289 4.3e-153 ywbI K Transcriptional regulator
DOFFALOB_02290 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DOFFALOB_02291 4.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
DOFFALOB_02292 8.2e-255 P COG0672 High-affinity Fe2 Pb2 permease
DOFFALOB_02293 2e-187 ycdO P periplasmic lipoprotein involved in iron transport
DOFFALOB_02294 2.6e-225 ywbN P Dyp-type peroxidase family protein
DOFFALOB_02295 1.9e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
DOFFALOB_02296 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DOFFALOB_02297 9.8e-49 ywcB S Protein of unknown function, DUF485
DOFFALOB_02299 2.2e-122 ywcC K transcriptional regulator
DOFFALOB_02300 9.5e-60 gtcA S GtrA-like protein
DOFFALOB_02301 6.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DOFFALOB_02302 3.7e-306 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
DOFFALOB_02303 1e-35 ywzA S membrane
DOFFALOB_02304 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
DOFFALOB_02305 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DOFFALOB_02306 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
DOFFALOB_02307 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
DOFFALOB_02308 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
DOFFALOB_02309 2.9e-202 rodA D Belongs to the SEDS family
DOFFALOB_02310 7.2e-138 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
DOFFALOB_02311 5.1e-187 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DOFFALOB_02312 0.0 vpr O Belongs to the peptidase S8 family
DOFFALOB_02314 2.4e-150 sacT K transcriptional antiterminator
DOFFALOB_02315 1e-139 focA P Formate/nitrite transporter
DOFFALOB_02316 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
DOFFALOB_02317 9.5e-296 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
DOFFALOB_02318 2e-28 ywdA
DOFFALOB_02319 9.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
DOFFALOB_02320 1.3e-57 pex K Transcriptional regulator PadR-like family
DOFFALOB_02321 1.4e-113 ywdD
DOFFALOB_02323 1.1e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
DOFFALOB_02324 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DOFFALOB_02325 5.9e-263 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
DOFFALOB_02326 7.7e-49 ywdI S Family of unknown function (DUF5327)
DOFFALOB_02327 1.3e-238 ywdJ F Xanthine uracil
DOFFALOB_02328 4.3e-59 ywdK S small membrane protein
DOFFALOB_02329 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
DOFFALOB_02330 2.8e-145 spsA M Spore Coat
DOFFALOB_02331 1.5e-269 spsB M Capsule polysaccharide biosynthesis protein
DOFFALOB_02332 1.6e-224 spsC E Belongs to the DegT DnrJ EryC1 family
DOFFALOB_02333 4e-164 spsD 2.3.1.210 K Spore Coat
DOFFALOB_02334 3.2e-214 spsE 2.5.1.56 M acid synthase
DOFFALOB_02335 9.7e-132 spsF M Spore Coat
DOFFALOB_02336 1.7e-190 spsG M Spore Coat
DOFFALOB_02337 1.9e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DOFFALOB_02338 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DOFFALOB_02339 5.3e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
DOFFALOB_02340 3.5e-87 spsL 5.1.3.13 M Spore Coat
DOFFALOB_02341 1.8e-78
DOFFALOB_02342 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
DOFFALOB_02343 1.4e-297 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
DOFFALOB_02344 0.0 rocB E arginine degradation protein
DOFFALOB_02345 4e-262 lysP E amino acid
DOFFALOB_02346 4.6e-206 ywfA EGP Major facilitator Superfamily
DOFFALOB_02347 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
DOFFALOB_02348 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
DOFFALOB_02349 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DOFFALOB_02350 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
DOFFALOB_02351 2.9e-210 bacE EGP Major facilitator Superfamily
DOFFALOB_02352 2.7e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
DOFFALOB_02353 4e-139 IQ Enoyl-(Acyl carrier protein) reductase
DOFFALOB_02354 1.1e-146 ywfI C May function as heme-dependent peroxidase
DOFFALOB_02355 6.6e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
DOFFALOB_02356 9.2e-164 cysL K Transcriptional regulator
DOFFALOB_02357 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
DOFFALOB_02358 5.2e-159 ywfM EG EamA-like transporter family
DOFFALOB_02359 1.6e-111 rsfA_1
DOFFALOB_02360 3.1e-36 ywzC S Belongs to the UPF0741 family
DOFFALOB_02361 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
DOFFALOB_02362 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
DOFFALOB_02363 2.8e-79 yffB K Transcriptional regulator
DOFFALOB_02364 2.6e-242 mmr U Major Facilitator Superfamily
DOFFALOB_02366 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DOFFALOB_02367 3.3e-71 ywhA K Transcriptional regulator
DOFFALOB_02368 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
DOFFALOB_02369 5.1e-119 ywhC S Peptidase family M50
DOFFALOB_02370 5.2e-95 ywhD S YwhD family
DOFFALOB_02371 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
DOFFALOB_02372 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DOFFALOB_02373 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
DOFFALOB_02374 1e-84 ywhH S Aminoacyl-tRNA editing domain
DOFFALOB_02376 2.3e-79 S aspartate phosphatase
DOFFALOB_02377 2.5e-205 ywhK CO amine dehydrogenase activity
DOFFALOB_02378 2.9e-249 ywhL CO amine dehydrogenase activity
DOFFALOB_02380 1.2e-249 L Peptidase, M16
DOFFALOB_02381 2.7e-219 2.7.1.26, 2.7.7.2 L Peptidase, M16
DOFFALOB_02382 3.1e-237 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
DOFFALOB_02383 3.3e-132 cbiO V ABC transporter
DOFFALOB_02385 2.6e-271 C Fe-S oxidoreductases
DOFFALOB_02386 1e-07 S Bacteriocin subtilosin A
DOFFALOB_02387 4.7e-73 ywiB S protein conserved in bacteria
DOFFALOB_02388 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
DOFFALOB_02389 9.8e-214 narK P COG2223 Nitrate nitrite transporter
DOFFALOB_02390 5.3e-130 fnr K helix_turn_helix, cAMP Regulatory protein
DOFFALOB_02391 1.7e-139 ywiC S YwiC-like protein
DOFFALOB_02392 7e-86 arfM T cyclic nucleotide binding
DOFFALOB_02393 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DOFFALOB_02394 1.9e-296 narH 1.7.5.1 C Nitrate reductase, beta
DOFFALOB_02395 3.1e-93 narJ 1.7.5.1 C nitrate reductase
DOFFALOB_02396 1.8e-124 narI 1.7.5.1 C nitrate reductase, gamma
DOFFALOB_02397 6.4e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DOFFALOB_02398 0.0 ywjA V ABC transporter
DOFFALOB_02399 4.8e-96 ywjB H RibD C-terminal domain
DOFFALOB_02400 2.7e-42 ywjC
DOFFALOB_02401 6.6e-184 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
DOFFALOB_02402 2.3e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
DOFFALOB_02403 0.0 fadF C COG0247 Fe-S oxidoreductase
DOFFALOB_02404 2.6e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
DOFFALOB_02405 1.5e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
DOFFALOB_02406 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DOFFALOB_02407 2.4e-92 ywjG S Domain of unknown function (DUF2529)
DOFFALOB_02408 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
DOFFALOB_02409 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
DOFFALOB_02410 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DOFFALOB_02411 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DOFFALOB_02412 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
DOFFALOB_02413 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DOFFALOB_02414 1.1e-32 rpmE J Binds the 23S rRNA
DOFFALOB_02415 2.4e-104 tdk 2.7.1.21 F thymidine kinase
DOFFALOB_02416 0.0 sfcA 1.1.1.38 C malic enzyme
DOFFALOB_02417 8.6e-160 ywkB S Membrane transport protein
DOFFALOB_02418 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
DOFFALOB_02419 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DOFFALOB_02420 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DOFFALOB_02421 4.3e-158 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DOFFALOB_02423 3.4e-56 ywlA S Uncharacterised protein family (UPF0715)
DOFFALOB_02424 6.1e-112 spoIIR S stage II sporulation protein R
DOFFALOB_02425 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
DOFFALOB_02426 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
DOFFALOB_02427 1.7e-91 mntP P Probably functions as a manganese efflux pump
DOFFALOB_02428 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DOFFALOB_02429 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
DOFFALOB_02430 7.2e-95 ywlG S Belongs to the UPF0340 family
DOFFALOB_02431 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DOFFALOB_02432 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DOFFALOB_02433 2.5e-62 atpI S ATP synthase
DOFFALOB_02434 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
DOFFALOB_02435 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DOFFALOB_02436 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DOFFALOB_02437 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DOFFALOB_02438 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DOFFALOB_02439 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DOFFALOB_02440 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DOFFALOB_02441 5.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
DOFFALOB_02442 4.3e-88 ywmA
DOFFALOB_02443 1.3e-32 ywzB S membrane
DOFFALOB_02444 1.6e-134 ywmB S TATA-box binding
DOFFALOB_02445 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DOFFALOB_02446 2e-178 spoIID D Stage II sporulation protein D
DOFFALOB_02447 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
DOFFALOB_02448 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
DOFFALOB_02450 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DOFFALOB_02451 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DOFFALOB_02452 1.3e-103 S response regulator aspartate phosphatase
DOFFALOB_02453 3e-84 ywmF S Peptidase M50
DOFFALOB_02454 3.8e-11 csbD K CsbD-like
DOFFALOB_02456 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
DOFFALOB_02457 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
DOFFALOB_02458 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
DOFFALOB_02459 1.7e-64 ywnA K Transcriptional regulator
DOFFALOB_02460 1.6e-114 ywnB S NAD(P)H-binding
DOFFALOB_02461 2.6e-59 ywnC S Family of unknown function (DUF5362)
DOFFALOB_02462 4.1e-144 mta K transcriptional
DOFFALOB_02463 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DOFFALOB_02464 2.2e-70 ywnF S Family of unknown function (DUF5392)
DOFFALOB_02465 2.7e-14 ywnC S Family of unknown function (DUF5362)
DOFFALOB_02466 6.4e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
DOFFALOB_02467 5.5e-126 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
DOFFALOB_02468 3.5e-73 ywnJ S VanZ like family
DOFFALOB_02469 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
DOFFALOB_02470 1.6e-58 nrgB K Belongs to the P(II) protein family
DOFFALOB_02471 2.5e-225 amt P Ammonium transporter
DOFFALOB_02472 2.2e-76
DOFFALOB_02473 4e-104 phzA Q Isochorismatase family
DOFFALOB_02474 4.4e-242 ywoD EGP Major facilitator superfamily
DOFFALOB_02475 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
DOFFALOB_02476 1.2e-231 ywoF P Right handed beta helix region
DOFFALOB_02477 2.7e-211 ywoG EGP Major facilitator Superfamily
DOFFALOB_02478 2.1e-70 ywoH K COG1846 Transcriptional regulators
DOFFALOB_02479 3e-44 spoIIID K Stage III sporulation protein D
DOFFALOB_02480 3.5e-180 mbl D Rod shape-determining protein
DOFFALOB_02481 6.9e-126 flhO N flagellar basal body
DOFFALOB_02482 1.5e-141 flhP N flagellar basal body
DOFFALOB_02483 2.1e-199 S aspartate phosphatase
DOFFALOB_02484 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
DOFFALOB_02485 1.5e-54 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DOFFALOB_02486 1.9e-153 ywpD T Histidine kinase
DOFFALOB_02487 8e-51 srtA 3.4.22.70 M Sortase family
DOFFALOB_02488 1.1e-66 ywpF S YwpF-like protein
DOFFALOB_02489 1.3e-66 ywpG
DOFFALOB_02490 9.8e-58 ssbB L Single-stranded DNA-binding protein
DOFFALOB_02491 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
DOFFALOB_02492 3.6e-157 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
DOFFALOB_02493 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
DOFFALOB_02494 3.8e-309 ywqB S SWIM zinc finger
DOFFALOB_02495 1.2e-17
DOFFALOB_02496 2e-116 ywqC M biosynthesis protein
DOFFALOB_02497 1.1e-119 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
DOFFALOB_02498 1.4e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
DOFFALOB_02499 3e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DOFFALOB_02500 3.4e-154 ywqG S Domain of unknown function (DUF1963)
DOFFALOB_02501 3.3e-15 S Domain of unknown function (DUF5082)
DOFFALOB_02502 1.3e-38 ywqI S Family of unknown function (DUF5344)
DOFFALOB_02503 0.0 ywqJ L nucleic acid phosphodiester bond hydrolysis
DOFFALOB_02504 1.7e-52 S MORN repeat variant
DOFFALOB_02505 4.5e-137 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
DOFFALOB_02506 2.9e-162 K Transcriptional regulator
DOFFALOB_02507 2.7e-102 ywqN S NAD(P)H-dependent
DOFFALOB_02509 6.9e-90 ywrA P COG2059 Chromate transport protein ChrA
DOFFALOB_02510 2.4e-104 ywrB P Chromate transporter
DOFFALOB_02511 2.1e-82 ywrC K Transcriptional regulator
DOFFALOB_02512 9.6e-310 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
DOFFALOB_02513 2.9e-54 S Domain of unknown function (DUF4181)
DOFFALOB_02514 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DOFFALOB_02515 3.7e-12
DOFFALOB_02516 1.2e-210 cotH M Spore Coat
DOFFALOB_02517 7.6e-131 cotB
DOFFALOB_02518 7.5e-126 ywrJ
DOFFALOB_02519 1.9e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DOFFALOB_02520 1.1e-169 alsR K LysR substrate binding domain
DOFFALOB_02521 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
DOFFALOB_02522 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
DOFFALOB_02523 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
DOFFALOB_02524 3.6e-48 ywsA S Protein of unknown function (DUF3892)
DOFFALOB_02525 4.6e-94 batE T Sh3 type 3 domain protein
DOFFALOB_02526 4.4e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
DOFFALOB_02527 1.4e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
DOFFALOB_02528 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
DOFFALOB_02529 2.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
DOFFALOB_02530 2.9e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DOFFALOB_02531 1.9e-178 rbsR K transcriptional
DOFFALOB_02532 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
DOFFALOB_02533 8.6e-70 pgsC S biosynthesis protein
DOFFALOB_02534 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
DOFFALOB_02535 3.6e-21 ywtC
DOFFALOB_02536 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
DOFFALOB_02537 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
DOFFALOB_02538 8.4e-171 ywtF K Transcriptional regulator
DOFFALOB_02539 1.9e-248 ywtG EGP Major facilitator Superfamily
DOFFALOB_02540 7.6e-216 gerAC S Spore germination protein
DOFFALOB_02541 7.5e-200 gerBB E Spore germination protein
DOFFALOB_02542 3.5e-266 gerBA EG Spore germination protein
DOFFALOB_02543 7.1e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
DOFFALOB_02544 7.2e-217 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
DOFFALOB_02545 1.2e-260
DOFFALOB_02546 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DOFFALOB_02547 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
DOFFALOB_02548 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
DOFFALOB_02549 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
DOFFALOB_02550 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DOFFALOB_02551 1.1e-150 tagG GM Transport permease protein
DOFFALOB_02552 1.8e-279 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
DOFFALOB_02553 1.6e-100 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
DOFFALOB_02555 8.1e-257 ggaA M Glycosyltransferase like family 2
DOFFALOB_02556 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
DOFFALOB_02557 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
DOFFALOB_02558 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
DOFFALOB_02559 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
DOFFALOB_02560 6e-38
DOFFALOB_02561 0.0 lytB 3.5.1.28 D Stage II sporulation protein
DOFFALOB_02562 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
DOFFALOB_02563 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
DOFFALOB_02564 3.3e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
DOFFALOB_02565 7.4e-222 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
DOFFALOB_02566 2.4e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DOFFALOB_02567 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
DOFFALOB_02568 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
DOFFALOB_02569 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
DOFFALOB_02570 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
DOFFALOB_02571 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
DOFFALOB_02572 6e-163 yvhJ K Transcriptional regulator
DOFFALOB_02573 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
DOFFALOB_02574 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
DOFFALOB_02575 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DOFFALOB_02576 7.3e-155 degV S protein conserved in bacteria
DOFFALOB_02577 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DOFFALOB_02578 5.7e-46 comFB S Late competence development protein ComFB
DOFFALOB_02579 2.7e-129 comFC S Phosphoribosyl transferase domain
DOFFALOB_02580 7e-74 yvyF S flagellar protein
DOFFALOB_02581 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
DOFFALOB_02582 2.4e-78 flgN NOU FlgN protein
DOFFALOB_02583 1.2e-264 flgK N flagellar hook-associated protein
DOFFALOB_02584 1.1e-156 flgL N Belongs to the bacterial flagellin family
DOFFALOB_02585 2.6e-50 yviE
DOFFALOB_02586 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
DOFFALOB_02587 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DOFFALOB_02588 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DOFFALOB_02589 6.1e-57 flaG N flagellar protein FlaG
DOFFALOB_02590 1.3e-266 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DOFFALOB_02591 2.9e-69 fliS N flagellar protein FliS
DOFFALOB_02592 1.9e-08 fliT S bacterial-type flagellum organization
DOFFALOB_02593 2.8e-66
DOFFALOB_02594 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DOFFALOB_02595 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DOFFALOB_02596 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DOFFALOB_02597 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
DOFFALOB_02598 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
DOFFALOB_02599 1.6e-123 ftsE D cell division ATP-binding protein FtsE
DOFFALOB_02600 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
DOFFALOB_02601 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
DOFFALOB_02602 5.3e-56 swrA S Swarming motility protein
DOFFALOB_02603 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DOFFALOB_02604 7.9e-228 yvkA EGP Major facilitator Superfamily
DOFFALOB_02605 7e-101 yvkB K Transcriptional regulator
DOFFALOB_02606 0.0 yvkC 2.7.9.2 GT Phosphotransferase
DOFFALOB_02607 1.2e-30 csbA S protein conserved in bacteria
DOFFALOB_02608 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DOFFALOB_02609 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DOFFALOB_02610 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DOFFALOB_02611 6.7e-34 yvkN
DOFFALOB_02612 8e-49 yvlA
DOFFALOB_02613 3.4e-168 yvlB S Putative adhesin
DOFFALOB_02614 2.6e-26 pspB KT PspC domain
DOFFALOB_02615 1.2e-50 yvlD S Membrane
DOFFALOB_02616 2.7e-203 yvmA EGP Major facilitator Superfamily
DOFFALOB_02617 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
DOFFALOB_02618 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
DOFFALOB_02619 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
DOFFALOB_02620 5.5e-58 adcR K helix_turn_helix multiple antibiotic resistance protein
DOFFALOB_02621 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
DOFFALOB_02622 3.6e-134 yvoA K transcriptional
DOFFALOB_02623 8.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DOFFALOB_02624 6.8e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
DOFFALOB_02625 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DOFFALOB_02626 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DOFFALOB_02627 1.5e-164 yvoD P COG0370 Fe2 transport system protein B
DOFFALOB_02628 1.3e-119 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
DOFFALOB_02629 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
DOFFALOB_02630 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
DOFFALOB_02631 4.5e-140 yvpB NU protein conserved in bacteria
DOFFALOB_02632 4.8e-221 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DOFFALOB_02633 1.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
DOFFALOB_02634 6.6e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DOFFALOB_02635 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
DOFFALOB_02636 1.7e-116 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DOFFALOB_02637 3.1e-133 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DOFFALOB_02638 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
DOFFALOB_02639 8e-114 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
DOFFALOB_02640 4.6e-121
DOFFALOB_02641 0.0
DOFFALOB_02643 0.0 msbA2 3.6.3.44 V ABC transporter
DOFFALOB_02644 2.4e-278 S COG0457 FOG TPR repeat
DOFFALOB_02645 1.4e-102 usp CBM50 M protein conserved in bacteria
DOFFALOB_02646 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DOFFALOB_02647 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
DOFFALOB_02648 5.7e-166 rapZ S Displays ATPase and GTPase activities
DOFFALOB_02649 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
DOFFALOB_02650 1.4e-170 whiA K May be required for sporulation
DOFFALOB_02651 1.6e-36 crh G Phosphocarrier protein Chr
DOFFALOB_02652 8.6e-147 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
DOFFALOB_02653 1.8e-33
DOFFALOB_02654 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DOFFALOB_02655 2.3e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
DOFFALOB_02656 5.6e-141 yvcR V ABC transporter, ATP-binding protein
DOFFALOB_02657 0.0 yxdM V ABC transporter (permease)
DOFFALOB_02658 1.3e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DOFFALOB_02659 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
DOFFALOB_02660 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
DOFFALOB_02661 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
DOFFALOB_02662 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
DOFFALOB_02663 3.6e-174 yvdE K Transcriptional regulator
DOFFALOB_02664 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
DOFFALOB_02665 1.3e-235 mdxE G COG2182 Maltose-binding periplasmic proteins domains
DOFFALOB_02666 5.3e-245 malC P COG1175 ABC-type sugar transport systems, permease components
DOFFALOB_02667 7.8e-149 malD P transport
DOFFALOB_02668 1.2e-158 malA S Protein of unknown function (DUF1189)
DOFFALOB_02669 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
DOFFALOB_02670 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
DOFFALOB_02671 1.3e-122 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
DOFFALOB_02672 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DOFFALOB_02674 1.5e-183 S Patatin-like phospholipase
DOFFALOB_02675 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
DOFFALOB_02676 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
DOFFALOB_02677 4.1e-50 sugE P Small Multidrug Resistance protein
DOFFALOB_02678 6.7e-51 ykkC P Small Multidrug Resistance protein
DOFFALOB_02679 2.6e-106 yvdT K Transcriptional regulator
DOFFALOB_02680 1.8e-295 yveA E amino acid
DOFFALOB_02681 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
DOFFALOB_02682 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
DOFFALOB_02683 9.6e-266 pbpE V Beta-lactamase
DOFFALOB_02684 3.1e-127 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
DOFFALOB_02685 1.3e-48 MA20_18690 S Protein of unknown function (DUF3237)
DOFFALOB_02686 4.6e-93 padC Q Phenolic acid decarboxylase
DOFFALOB_02688 4.8e-287 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
DOFFALOB_02689 5.7e-77 slr K transcriptional
DOFFALOB_02690 4e-122 ywqC M biosynthesis protein
DOFFALOB_02691 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
DOFFALOB_02692 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
DOFFALOB_02693 2e-224 epsD GT4 M Glycosyl transferase 4-like
DOFFALOB_02694 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
DOFFALOB_02695 5.3e-220 epsF GT4 M Glycosyl transferases group 1
DOFFALOB_02696 4.8e-207 epsG S EpsG family
DOFFALOB_02697 3.6e-196 epsH GT2 S Glycosyltransferase like family 2
DOFFALOB_02698 3.6e-207 epsI GM pyruvyl transferase
DOFFALOB_02699 1.9e-197 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
DOFFALOB_02700 8.9e-260 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
DOFFALOB_02701 2.6e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
DOFFALOB_02702 2.2e-58 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
DOFFALOB_02703 1.2e-224 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
DOFFALOB_02704 5.8e-188 yvfF GM Exopolysaccharide biosynthesis protein
DOFFALOB_02705 1e-31 yvfG S YvfG protein
DOFFALOB_02706 6.5e-243 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
DOFFALOB_02707 1.4e-309 yvfH C L-lactate permease
DOFFALOB_02708 1e-112 yvfI K COG2186 Transcriptional regulators
DOFFALOB_02709 1.8e-184 lacR K Transcriptional regulator
DOFFALOB_02710 2.9e-232 cycB G COG2182 Maltose-binding periplasmic proteins domains
DOFFALOB_02711 1.3e-232 malC P COG1175 ABC-type sugar transport systems, permease components
DOFFALOB_02712 3.2e-150 ganQ P transport
DOFFALOB_02713 0.0 lacA 3.2.1.23 G beta-galactosidase
DOFFALOB_02714 2.6e-252 galA 3.2.1.89 G arabinogalactan
DOFFALOB_02715 1.4e-199 rsbU 3.1.3.3 T response regulator
DOFFALOB_02716 2.6e-157 rsbQ S Alpha/beta hydrolase family
DOFFALOB_02717 3e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
DOFFALOB_02718 6.2e-134 yvfS V COG0842 ABC-type multidrug transport system, permease component
DOFFALOB_02719 8.9e-201 desK 2.7.13.3 T Histidine kinase
DOFFALOB_02720 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DOFFALOB_02721 1.5e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
DOFFALOB_02722 1.2e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
DOFFALOB_02723 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
DOFFALOB_02724 4.3e-197 yvbX S Glycosyl hydrolase
DOFFALOB_02725 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
DOFFALOB_02726 8.5e-157 yvbV EG EamA-like transporter family
DOFFALOB_02727 3.9e-159 yvbU K Transcriptional regulator
DOFFALOB_02728 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DOFFALOB_02729 5.5e-203 araR K transcriptional
DOFFALOB_02730 1.6e-252 araE EGP Major facilitator Superfamily
DOFFALOB_02731 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
DOFFALOB_02732 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DOFFALOB_02733 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
DOFFALOB_02734 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DOFFALOB_02735 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
DOFFALOB_02736 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DOFFALOB_02737 7.7e-82 yvbK 3.1.3.25 K acetyltransferase
DOFFALOB_02738 0.0 tcaA S response to antibiotic
DOFFALOB_02739 4.2e-124 exoY M Membrane
DOFFALOB_02740 8.6e-113 yvbH S YvbH-like oligomerisation region
DOFFALOB_02741 6.4e-103 yvbG U UPF0056 membrane protein
DOFFALOB_02742 1.4e-98 yvbF K Belongs to the GbsR family
DOFFALOB_02743 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
DOFFALOB_02744 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
DOFFALOB_02745 2.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
DOFFALOB_02746 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
DOFFALOB_02747 4.5e-45 sdpR K transcriptional
DOFFALOB_02748 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
DOFFALOB_02749 4.4e-08
DOFFALOB_02750 7.6e-172
DOFFALOB_02751 7.9e-13 S Sporulation delaying protein SdpA
DOFFALOB_02752 8.7e-61 yvbF K Belongs to the GbsR family
DOFFALOB_02753 3e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
DOFFALOB_02754 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
DOFFALOB_02755 1.1e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
DOFFALOB_02756 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
DOFFALOB_02757 4.2e-226 NT chemotaxis protein
DOFFALOB_02758 2.2e-54 yodB K transcriptional
DOFFALOB_02759 8e-70 yvaO K Cro/C1-type HTH DNA-binding domain
DOFFALOB_02760 4e-69 K transcriptional
DOFFALOB_02761 7.5e-36 yvzC K Transcriptional
DOFFALOB_02762 3.7e-153 yvaM S Serine aminopeptidase, S33
DOFFALOB_02763 2.4e-23 secG U Preprotein translocase subunit SecG
DOFFALOB_02764 5.6e-143 est 3.1.1.1 S Carboxylesterase
DOFFALOB_02765 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
DOFFALOB_02766 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DOFFALOB_02768 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
DOFFALOB_02769 4.1e-101 K Bacterial regulatory proteins, tetR family
DOFFALOB_02770 2.8e-55 yvaE P Small Multidrug Resistance protein
DOFFALOB_02771 5.7e-73 yvaD S Family of unknown function (DUF5360)
DOFFALOB_02772 0.0 yvaC S Fusaric acid resistance protein-like
DOFFALOB_02773 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DOFFALOB_02774 2.1e-199 yvaA 1.1.1.371 S Oxidoreductase
DOFFALOB_02775 2.2e-48 csoR S transcriptional
DOFFALOB_02776 1.5e-29 copZ P Copper resistance protein CopZ
DOFFALOB_02777 0.0 copA 3.6.3.54 P P-type ATPase
DOFFALOB_02778 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
DOFFALOB_02779 1.6e-104 bdbD O Thioredoxin
DOFFALOB_02780 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
DOFFALOB_02781 4.1e-107 yvgT S membrane
DOFFALOB_02782 0.0 helD 3.6.4.12 L DNA helicase
DOFFALOB_02783 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DOFFALOB_02784 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
DOFFALOB_02785 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
DOFFALOB_02786 1.9e-68 yvgO
DOFFALOB_02787 9.1e-158 yvgN S reductase
DOFFALOB_02788 4.7e-120 modB P COG4149 ABC-type molybdate transport system, permease component
DOFFALOB_02789 5.8e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
DOFFALOB_02790 8e-171 yvgK P COG1910 Periplasmic molybdate-binding protein domain
DOFFALOB_02791 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
DOFFALOB_02792 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
DOFFALOB_02793 6.5e-16 S Small spore protein J (Spore_SspJ)
DOFFALOB_02794 2.6e-237 yvsH E Arginine ornithine antiporter
DOFFALOB_02796 2.1e-179 fhuD P ABC transporter
DOFFALOB_02797 9.3e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DOFFALOB_02798 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DOFFALOB_02799 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
DOFFALOB_02800 4.8e-176 M Efflux transporter rnd family, mfp subunit
DOFFALOB_02801 7.1e-124 macB V ABC transporter, ATP-binding protein
DOFFALOB_02802 1.8e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
DOFFALOB_02803 1.3e-64 yvrL S Regulatory protein YrvL
DOFFALOB_02804 7.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
DOFFALOB_02805 2.4e-19 S YvrJ protein family
DOFFALOB_02806 1.8e-96 yvrI K RNA polymerase
DOFFALOB_02807 3.6e-22
DOFFALOB_02808 3.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DOFFALOB_02809 0.0 T PhoQ Sensor
DOFFALOB_02810 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
DOFFALOB_02811 6.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
DOFFALOB_02812 1.8e-170 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
DOFFALOB_02813 7.7e-186 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DOFFALOB_02814 2.8e-249 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
DOFFALOB_02815 6.5e-102 yvqK 2.5.1.17 S Adenosyltransferase
DOFFALOB_02816 4.8e-227 yvqJ EGP Major facilitator Superfamily
DOFFALOB_02817 5.6e-62 liaI S membrane
DOFFALOB_02818 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
DOFFALOB_02819 9.3e-129 liaG S Putative adhesin
DOFFALOB_02820 5.6e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
DOFFALOB_02821 5.5e-187 vraS 2.7.13.3 T Histidine kinase
DOFFALOB_02822 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DOFFALOB_02823 6e-189 gerAC S Spore germination B3/ GerAC like, C-terminal
DOFFALOB_02824 9.1e-198 gerAB E Spore germination protein
DOFFALOB_02825 3.7e-247 gerAA EG Spore germination protein
DOFFALOB_02826 2.3e-24 S Protein of unknown function (DUF3970)
DOFFALOB_02827 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
DOFFALOB_02828 4.3e-158 yuxN K Transcriptional regulator
DOFFALOB_02829 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
DOFFALOB_02830 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DOFFALOB_02831 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DOFFALOB_02832 1.2e-79 dps P Ferritin-like domain
DOFFALOB_02833 4.7e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
DOFFALOB_02834 3.9e-34 pepF2 E COG1164 Oligoendopeptidase F
DOFFALOB_02835 1.4e-257 pepF2 E COG1164 Oligoendopeptidase F
DOFFALOB_02836 5.6e-66 S YusW-like protein
DOFFALOB_02837 1e-153 yusV 3.6.3.34 HP ABC transporter
DOFFALOB_02838 3.8e-47 yusU S Protein of unknown function (DUF2573)
DOFFALOB_02839 2.7e-160 yusT K LysR substrate binding domain
DOFFALOB_02840 2.5e-50 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
DOFFALOB_02841 2.5e-62 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
DOFFALOB_02842 8.4e-66 yusQ S Tautomerase enzyme
DOFFALOB_02843 3.8e-293 yusP P Major facilitator superfamily
DOFFALOB_02844 5.4e-75 yusO K Iron dependent repressor, N-terminal DNA binding domain
DOFFALOB_02845 3.2e-53 yusN M Coat F domain
DOFFALOB_02846 5.1e-40
DOFFALOB_02847 2.2e-165 fadM E Proline dehydrogenase
DOFFALOB_02848 4.7e-09 S YuzL-like protein
DOFFALOB_02849 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
DOFFALOB_02850 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
DOFFALOB_02851 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
DOFFALOB_02852 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
DOFFALOB_02853 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
DOFFALOB_02854 1.1e-39 yusG S Protein of unknown function (DUF2553)
DOFFALOB_02855 3.3e-74 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
DOFFALOB_02856 5.6e-55 traF CO Thioredoxin
DOFFALOB_02857 2.4e-56 yusD S SCP-2 sterol transfer family
DOFFALOB_02858 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DOFFALOB_02859 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
DOFFALOB_02860 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
DOFFALOB_02861 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DOFFALOB_02862 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
DOFFALOB_02863 1.4e-245 sufD O assembly protein SufD
DOFFALOB_02864 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DOFFALOB_02865 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
DOFFALOB_02866 3.5e-271 sufB O FeS cluster assembly
DOFFALOB_02867 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DOFFALOB_02868 1e-41
DOFFALOB_02870 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
DOFFALOB_02871 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
DOFFALOB_02872 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
DOFFALOB_02873 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
DOFFALOB_02874 1.4e-156 yurN G Binding-protein-dependent transport system inner membrane component
DOFFALOB_02875 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
DOFFALOB_02876 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
DOFFALOB_02877 1.1e-135 yurK K UTRA
DOFFALOB_02878 1.2e-205 msmX P Belongs to the ABC transporter superfamily
DOFFALOB_02879 2.4e-169 bsn L Ribonuclease
DOFFALOB_02880 1.6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
DOFFALOB_02881 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
DOFFALOB_02883 1.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DOFFALOB_02884 3.6e-111 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
DOFFALOB_02885 3.4e-152 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
DOFFALOB_02886 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
DOFFALOB_02887 1.8e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
DOFFALOB_02888 2.7e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
DOFFALOB_02889 7.3e-283 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
DOFFALOB_02890 1.3e-222 pbuX F xanthine
DOFFALOB_02891 2.1e-236 pbuX F Permease family
DOFFALOB_02892 1.2e-302 pucR QT COG2508 Regulator of polyketide synthase expression
DOFFALOB_02893 1e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
DOFFALOB_02894 3e-62 yunG
DOFFALOB_02895 4.3e-171 yunF S Protein of unknown function DUF72
DOFFALOB_02896 2e-141 yunE S membrane transporter protein
DOFFALOB_02897 5.8e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
DOFFALOB_02898 4.8e-48 yunC S Domain of unknown function (DUF1805)
DOFFALOB_02899 8.4e-134 yunB S Sporulation protein YunB (Spo_YunB)
DOFFALOB_02900 4.5e-196 lytH M Peptidase, M23
DOFFALOB_02901 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DOFFALOB_02902 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
DOFFALOB_02903 9.7e-48 yutD S protein conserved in bacteria
DOFFALOB_02904 1e-75 yutE S Protein of unknown function DUF86
DOFFALOB_02905 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
DOFFALOB_02906 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
DOFFALOB_02907 2e-199 yutH S Spore coat protein
DOFFALOB_02908 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
DOFFALOB_02909 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DOFFALOB_02910 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
DOFFALOB_02911 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
DOFFALOB_02912 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
DOFFALOB_02913 3.5e-57 yuzD S protein conserved in bacteria
DOFFALOB_02914 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
DOFFALOB_02915 3.2e-39 yuzB S Belongs to the UPF0349 family
DOFFALOB_02916 2.4e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DOFFALOB_02917 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DOFFALOB_02918 3.7e-63 erpA S Belongs to the HesB IscA family
DOFFALOB_02919 2.2e-74 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DOFFALOB_02920 9e-118 paiB K Putative FMN-binding domain
DOFFALOB_02921 4.9e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DOFFALOB_02923 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
DOFFALOB_02924 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
DOFFALOB_02925 8.4e-27 yuiB S Putative membrane protein
DOFFALOB_02926 5.6e-118 yuiC S protein conserved in bacteria
DOFFALOB_02927 1.2e-77 yuiD S protein conserved in bacteria
DOFFALOB_02928 1.5e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DOFFALOB_02929 3.9e-211 yuiF S antiporter
DOFFALOB_02930 1.1e-93 bioY S Biotin biosynthesis protein
DOFFALOB_02931 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
DOFFALOB_02932 1.3e-167 besA S Putative esterase
DOFFALOB_02933 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
DOFFALOB_02934 2.3e-226 entC 5.4.4.2 HQ Isochorismate synthase
DOFFALOB_02935 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
DOFFALOB_02936 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
DOFFALOB_02937 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DOFFALOB_02938 3.8e-36 mbtH S MbtH-like protein
DOFFALOB_02939 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
DOFFALOB_02940 1.2e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
DOFFALOB_02941 6.5e-229 yukF QT Transcriptional regulator
DOFFALOB_02942 2.8e-45 esxA S Belongs to the WXG100 family
DOFFALOB_02943 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
DOFFALOB_02944 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
DOFFALOB_02945 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
DOFFALOB_02946 0.0 esaA S type VII secretion protein EsaA
DOFFALOB_02947 6.6e-65 yueC S Family of unknown function (DUF5383)
DOFFALOB_02948 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DOFFALOB_02949 4.8e-96 yueE S phosphohydrolase
DOFFALOB_02950 2.9e-24 S Protein of unknown function (DUF2642)
DOFFALOB_02951 6.1e-72 S Protein of unknown function (DUF2283)
DOFFALOB_02952 1.9e-190 yueF S transporter activity
DOFFALOB_02953 2.1e-32 yueG S Spore germination protein gerPA/gerPF
DOFFALOB_02954 7.4e-39 yueH S YueH-like protein
DOFFALOB_02955 1.6e-67 yueI S Protein of unknown function (DUF1694)
DOFFALOB_02956 2.9e-104 pncA Q COG1335 Amidases related to nicotinamidase
DOFFALOB_02957 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DOFFALOB_02958 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
DOFFALOB_02959 1.1e-22 yuzC
DOFFALOB_02961 2.5e-162 comQ H Polyprenyl synthetase
DOFFALOB_02963 0.0 comP 2.7.13.3 T Histidine kinase
DOFFALOB_02964 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DOFFALOB_02965 9.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
DOFFALOB_02966 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
DOFFALOB_02967 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
DOFFALOB_02968 4.8e-79 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
DOFFALOB_02969 3.8e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
DOFFALOB_02970 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
DOFFALOB_02971 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
DOFFALOB_02972 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
DOFFALOB_02973 1.9e-14
DOFFALOB_02974 1.3e-233 maeN C COG3493 Na citrate symporter
DOFFALOB_02975 4.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
DOFFALOB_02976 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
DOFFALOB_02977 1.1e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
DOFFALOB_02978 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
DOFFALOB_02979 2.3e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
DOFFALOB_02980 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
DOFFALOB_02981 6.3e-78 yufK S Family of unknown function (DUF5366)
DOFFALOB_02982 6.3e-75 yuxK S protein conserved in bacteria
DOFFALOB_02983 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
DOFFALOB_02984 3.5e-186 yuxJ EGP Major facilitator Superfamily
DOFFALOB_02986 1.9e-115 kapD L the KinA pathway to sporulation
DOFFALOB_02987 2e-70 kapB G Kinase associated protein B
DOFFALOB_02988 4.6e-233 T PhoQ Sensor
DOFFALOB_02989 1.8e-228 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
DOFFALOB_02990 9.8e-42 yugE S Domain of unknown function (DUF1871)
DOFFALOB_02991 1e-156 yugF I Hydrolase
DOFFALOB_02992 1.6e-85 alaR K Transcriptional regulator
DOFFALOB_02993 4.3e-200 yugH 2.6.1.1 E Aminotransferase
DOFFALOB_02994 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
DOFFALOB_02995 1.1e-34 yuzA S Domain of unknown function (DUF378)
DOFFALOB_02996 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
DOFFALOB_02997 2.8e-229 yugK C Dehydrogenase
DOFFALOB_02998 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
DOFFALOB_03000 1.3e-72 yugN S YugN-like family
DOFFALOB_03001 1.7e-182 yugO P COG1226 Kef-type K transport systems
DOFFALOB_03002 1.1e-53 mstX S Membrane-integrating protein Mistic
DOFFALOB_03003 4.6e-39
DOFFALOB_03004 1.4e-116 yugP S Zn-dependent protease
DOFFALOB_03005 2.6e-236 yugS S COG1253 Hemolysins and related proteins containing CBS domains
DOFFALOB_03006 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
DOFFALOB_03007 2.1e-72 yugU S Uncharacterised protein family UPF0047
DOFFALOB_03008 1e-35
DOFFALOB_03009 2.6e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
DOFFALOB_03010 3.2e-225 mcpA NT chemotaxis protein
DOFFALOB_03011 1.5e-222 mcpA NT chemotaxis protein
DOFFALOB_03012 2.2e-295 mcpA NT chemotaxis protein
DOFFALOB_03013 5.1e-239 mcpA NT chemotaxis protein
DOFFALOB_03014 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
DOFFALOB_03015 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
DOFFALOB_03016 1.3e-281 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
DOFFALOB_03017 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
DOFFALOB_03018 1.4e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
DOFFALOB_03019 3.3e-183 ygjR S Oxidoreductase
DOFFALOB_03020 6.3e-197 yubA S transporter activity
DOFFALOB_03021 1.2e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
DOFFALOB_03023 2.6e-88 cdoA 1.13.11.20 S Cysteine dioxygenase type I
DOFFALOB_03024 6.2e-277 yubD P Major Facilitator Superfamily
DOFFALOB_03025 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
DOFFALOB_03026 1e-38 yiaA S yiaA/B two helix domain
DOFFALOB_03027 5.4e-237 ktrB P Potassium
DOFFALOB_03028 5e-122 ktrA P COG0569 K transport systems, NAD-binding component
DOFFALOB_03029 2.2e-91 yuaB
DOFFALOB_03030 1.1e-95 yuaC K Belongs to the GbsR family
DOFFALOB_03031 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
DOFFALOB_03032 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
DOFFALOB_03033 7.9e-108 yuaD
DOFFALOB_03034 3.9e-84 yuaE S DinB superfamily
DOFFALOB_03035 1.4e-77 yuaF OU Membrane protein implicated in regulation of membrane protease activity
DOFFALOB_03036 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
DOFFALOB_03037 3.4e-94 M1-753 M FR47-like protein
DOFFALOB_03038 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
DOFFALOB_03039 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
DOFFALOB_03041 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
DOFFALOB_03042 2.2e-142 ybbA S Putative esterase
DOFFALOB_03043 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DOFFALOB_03044 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DOFFALOB_03045 7.2e-167 feuA P Iron-uptake system-binding protein
DOFFALOB_03046 5.4e-308 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
DOFFALOB_03047 4.4e-241 ybbC 3.2.1.52 S protein conserved in bacteria
DOFFALOB_03048 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
DOFFALOB_03049 4e-256 yfeW 3.4.16.4 V Belongs to the UPF0214 family
DOFFALOB_03050 9.8e-234 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
DOFFALOB_03051 1.1e-150 ybbH K transcriptional
DOFFALOB_03052 2.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DOFFALOB_03053 6.4e-87 ybbJ J acetyltransferase
DOFFALOB_03054 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
DOFFALOB_03060 8.5e-99 sigW K Belongs to the sigma-70 factor family. ECF subfamily
DOFFALOB_03061 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
DOFFALOB_03062 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DOFFALOB_03063 3e-225 ybbR S protein conserved in bacteria
DOFFALOB_03064 9.3e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DOFFALOB_03065 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DOFFALOB_03066 2.1e-176 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DOFFALOB_03067 1.4e-121 adaA 3.2.2.21 K Transcriptional regulator
DOFFALOB_03068 5.1e-101 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DOFFALOB_03069 1.5e-278 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
DOFFALOB_03070 0.0 ybcC S Belongs to the UPF0753 family
DOFFALOB_03071 3.7e-96 can 4.2.1.1 P carbonic anhydrase
DOFFALOB_03072 3.9e-47
DOFFALOB_03073 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
DOFFALOB_03074 5.1e-50 ybzH K Helix-turn-helix domain
DOFFALOB_03075 2e-203 ybcL EGP Major facilitator Superfamily
DOFFALOB_03077 1e-237 J 4Fe-4S single cluster domain
DOFFALOB_03078 1.6e-277 V CAAX protease self-immunity
DOFFALOB_03079 1.9e-135 skfE V ABC transporter
DOFFALOB_03080 4e-248 skfF S ABC transporter
DOFFALOB_03081 7.8e-91 C HEAT repeats
DOFFALOB_03082 9.6e-79 txn CO Thioredoxin-like
DOFFALOB_03083 6.2e-182 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
DOFFALOB_03084 1.5e-123 T Transcriptional regulatory protein, C terminal
DOFFALOB_03085 1.8e-173 T His Kinase A (phospho-acceptor) domain
DOFFALOB_03087 1.6e-140 KLT Protein tyrosine kinase
DOFFALOB_03088 4.8e-154 ybdN
DOFFALOB_03089 1.5e-217 ybdO S Domain of unknown function (DUF4885)
DOFFALOB_03090 2.4e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
DOFFALOB_03091 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
DOFFALOB_03092 4.9e-30 ybxH S Family of unknown function (DUF5370)
DOFFALOB_03093 7.2e-152 ybxI 3.5.2.6 V beta-lactamase
DOFFALOB_03094 1.4e-247 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
DOFFALOB_03095 4.9e-41 ybyB
DOFFALOB_03096 2.3e-290 ybeC E amino acid
DOFFALOB_03097 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
DOFFALOB_03098 7.3e-258 glpT G -transporter
DOFFALOB_03099 2.9e-35 S Protein of unknown function (DUF2651)
DOFFALOB_03100 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
DOFFALOB_03101 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
DOFFALOB_03103 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
DOFFALOB_03104 8.8e-162 ybfH EG EamA-like transporter family
DOFFALOB_03105 2.3e-145 msmR K AraC-like ligand binding domain
DOFFALOB_03106 1.9e-214 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DOFFALOB_03107 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
DOFFALOB_03109 2.5e-169 S Alpha/beta hydrolase family
DOFFALOB_03110 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DOFFALOB_03111 2.7e-85 ybfM S SNARE associated Golgi protein
DOFFALOB_03112 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
DOFFALOB_03113 3.2e-46 ybfN
DOFFALOB_03114 4.3e-258 S Erythromycin esterase
DOFFALOB_03115 6.7e-167 ybfP K Transcriptional regulator
DOFFALOB_03116 3.9e-192 yceA S Belongs to the UPF0176 family
DOFFALOB_03117 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DOFFALOB_03118 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
DOFFALOB_03119 2.1e-137 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DOFFALOB_03120 4.9e-128 K UTRA
DOFFALOB_03122 5.4e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
DOFFALOB_03123 6.7e-262 mmuP E amino acid
DOFFALOB_03124 9.3e-183 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
DOFFALOB_03125 2.3e-257 agcS E Sodium alanine symporter
DOFFALOB_03126 2.9e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
DOFFALOB_03127 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
DOFFALOB_03128 9e-170 glnL T Regulator
DOFFALOB_03129 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
DOFFALOB_03130 3.7e-274 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
DOFFALOB_03131 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
DOFFALOB_03132 2.2e-270 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
DOFFALOB_03133 1.5e-124 ycbG K FCD
DOFFALOB_03134 3.7e-298 garD 4.2.1.42, 4.2.1.7 G Altronate
DOFFALOB_03135 1.8e-178 ycbJ S Macrolide 2'-phosphotransferase
DOFFALOB_03136 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
DOFFALOB_03137 7.3e-172 eamA1 EG spore germination
DOFFALOB_03138 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DOFFALOB_03139 2.4e-170 T PhoQ Sensor
DOFFALOB_03140 4.8e-168 ycbN V ABC transporter, ATP-binding protein
DOFFALOB_03141 2.1e-115 S ABC-2 family transporter protein
DOFFALOB_03142 8.2e-53 ycbP S Protein of unknown function (DUF2512)
DOFFALOB_03143 1.3e-78 sleB 3.5.1.28 M Cell wall
DOFFALOB_03144 6.6e-136 ycbR T vWA found in TerF C terminus
DOFFALOB_03145 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
DOFFALOB_03146 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
DOFFALOB_03147 1.2e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DOFFALOB_03148 1.4e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DOFFALOB_03149 6.2e-210 ycbU E Selenocysteine lyase
DOFFALOB_03150 5.8e-229 lmrB EGP the major facilitator superfamily
DOFFALOB_03151 4.8e-102 yxaF K Transcriptional regulator
DOFFALOB_03152 2.2e-202 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
DOFFALOB_03153 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
DOFFALOB_03154 2e-59 S RDD family
DOFFALOB_03155 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
DOFFALOB_03156 2e-161 2.7.13.3 T GHKL domain
DOFFALOB_03157 1.2e-126 lytR_2 T LytTr DNA-binding domain
DOFFALOB_03158 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
DOFFALOB_03159 4.5e-203 natB CP ABC-2 family transporter protein
DOFFALOB_03160 1.6e-174 yccK C Aldo keto reductase
DOFFALOB_03161 6.6e-177 ycdA S Domain of unknown function (DUF5105)
DOFFALOB_03162 5.9e-282 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
DOFFALOB_03163 6.7e-268 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
DOFFALOB_03164 1.7e-95 cwlK M D-alanyl-D-alanine carboxypeptidase
DOFFALOB_03165 5.5e-174 S response regulator aspartate phosphatase
DOFFALOB_03166 1.6e-140 IQ Enoyl-(Acyl carrier protein) reductase
DOFFALOB_03167 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
DOFFALOB_03168 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
DOFFALOB_03169 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
DOFFALOB_03170 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
DOFFALOB_03171 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DOFFALOB_03172 3.9e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
DOFFALOB_03173 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
DOFFALOB_03174 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
DOFFALOB_03175 6.3e-137 terC P Protein of unknown function (DUF475)
DOFFALOB_03176 0.0 yceG S Putative component of 'biosynthetic module'
DOFFALOB_03177 2e-192 yceH P Belongs to the TelA family
DOFFALOB_03178 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
DOFFALOB_03179 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
DOFFALOB_03180 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
DOFFALOB_03181 5.1e-229 proV 3.6.3.32 E glycine betaine
DOFFALOB_03182 1.3e-127 opuAB P glycine betaine
DOFFALOB_03183 5.3e-164 opuAC E glycine betaine
DOFFALOB_03184 1.2e-219 amhX S amidohydrolase
DOFFALOB_03185 8.7e-257 ycgA S Membrane
DOFFALOB_03186 1.1e-98 ycgB
DOFFALOB_03187 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
DOFFALOB_03188 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
DOFFALOB_03189 6.5e-293 lctP C L-lactate permease
DOFFALOB_03190 6.2e-269 mdr EGP Major facilitator Superfamily
DOFFALOB_03191 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
DOFFALOB_03192 6.8e-113 ycgF E Lysine exporter protein LysE YggA
DOFFALOB_03193 1.2e-151 yqcI S YqcI/YcgG family
DOFFALOB_03194 5.6e-250 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
DOFFALOB_03195 2.4e-112 ycgI S Domain of unknown function (DUF1989)
DOFFALOB_03196 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
DOFFALOB_03197 2.5e-109 tmrB S AAA domain
DOFFALOB_03198 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DOFFALOB_03199 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
DOFFALOB_03200 2.2e-179 oxyR3 K LysR substrate binding domain
DOFFALOB_03201 2.9e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
DOFFALOB_03202 2.9e-145 ycgL S Predicted nucleotidyltransferase
DOFFALOB_03203 5.1e-170 ycgM E Proline dehydrogenase
DOFFALOB_03204 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
DOFFALOB_03205 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DOFFALOB_03206 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
DOFFALOB_03207 2.6e-147 ycgQ S membrane
DOFFALOB_03208 1.2e-139 ycgR S permeases
DOFFALOB_03209 5.7e-163 I alpha/beta hydrolase fold
DOFFALOB_03210 1.3e-193 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
DOFFALOB_03211 9.3e-283 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
DOFFALOB_03212 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
DOFFALOB_03213 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DOFFALOB_03214 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DOFFALOB_03215 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
DOFFALOB_03216 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
DOFFALOB_03217 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
DOFFALOB_03218 5.5e-109 yciB M ErfK YbiS YcfS YnhG
DOFFALOB_03219 1.4e-228 yciC S GTPases (G3E family)
DOFFALOB_03220 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
DOFFALOB_03221 1.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
DOFFALOB_03224 3.3e-77 yckC S membrane
DOFFALOB_03225 3.5e-52 yckD S Protein of unknown function (DUF2680)
DOFFALOB_03226 1.2e-298 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DOFFALOB_03227 3.4e-70 nin S Competence protein J (ComJ)
DOFFALOB_03228 3.2e-72 nucA M Deoxyribonuclease NucA/NucB
DOFFALOB_03229 3e-187 tlpC 2.7.13.3 NT chemotaxis protein
DOFFALOB_03230 4.6e-97 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
DOFFALOB_03231 3.3e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
DOFFALOB_03232 1.3e-63 hxlR K transcriptional
DOFFALOB_03233 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DOFFALOB_03234 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DOFFALOB_03235 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
DOFFALOB_03236 5.7e-140 srfAD Q thioesterase
DOFFALOB_03237 4.2e-228 EGP Major Facilitator Superfamily
DOFFALOB_03238 4.9e-91 S YcxB-like protein
DOFFALOB_03239 7.4e-164 ycxC EG EamA-like transporter family
DOFFALOB_03240 4.4e-255 ycxD K GntR family transcriptional regulator
DOFFALOB_03241 5.5e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
DOFFALOB_03242 4.4e-115 yczE S membrane
DOFFALOB_03243 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
DOFFALOB_03244 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
DOFFALOB_03245 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
DOFFALOB_03246 4.9e-162 bsdA K LysR substrate binding domain
DOFFALOB_03247 2e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
DOFFALOB_03248 1.8e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
DOFFALOB_03249 4e-39 bsdD 4.1.1.61 S response to toxic substance
DOFFALOB_03250 1.1e-83 yclD
DOFFALOB_03251 6.2e-162 yclE 3.4.11.5 S Alpha beta hydrolase
DOFFALOB_03252 1.5e-267 dtpT E amino acid peptide transporter
DOFFALOB_03253 2.9e-310 yclG M Pectate lyase superfamily protein
DOFFALOB_03255 6.8e-282 gerKA EG Spore germination protein
DOFFALOB_03256 1.3e-232 gerKC S spore germination
DOFFALOB_03257 9.9e-200 gerKB F Spore germination protein
DOFFALOB_03258 3.9e-122 yclH P ABC transporter
DOFFALOB_03259 3.3e-200 yclI V ABC transporter (permease) YclI
DOFFALOB_03260 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DOFFALOB_03261 1.8e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
DOFFALOB_03262 5.2e-71 S aspartate phosphatase
DOFFALOB_03265 7.5e-242 lysC 2.7.2.4 E Belongs to the aspartokinase family
DOFFALOB_03266 1.6e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DOFFALOB_03267 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DOFFALOB_03268 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
DOFFALOB_03269 5.5e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
DOFFALOB_03270 1.4e-251 ycnB EGP Major facilitator Superfamily
DOFFALOB_03271 6.5e-154 ycnC K Transcriptional regulator
DOFFALOB_03272 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
DOFFALOB_03273 1.6e-45 ycnE S Monooxygenase
DOFFALOB_03274 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
DOFFALOB_03275 1.3e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
DOFFALOB_03276 4.4e-247 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DOFFALOB_03277 3.4e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
DOFFALOB_03278 6.1e-149 glcU U Glucose uptake
DOFFALOB_03279 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DOFFALOB_03280 1.3e-100 ycnI S protein conserved in bacteria
DOFFALOB_03281 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
DOFFALOB_03282 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
DOFFALOB_03283 7.3e-56
DOFFALOB_03284 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
DOFFALOB_03285 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
DOFFALOB_03286 7.3e-211 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
DOFFALOB_03287 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
DOFFALOB_03288 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
DOFFALOB_03289 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
DOFFALOB_03290 5e-113 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
DOFFALOB_03291 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
DOFFALOB_03293 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
DOFFALOB_03294 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
DOFFALOB_03295 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
DOFFALOB_03296 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
DOFFALOB_03297 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
DOFFALOB_03298 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
DOFFALOB_03299 1.2e-132 kipR K Transcriptional regulator
DOFFALOB_03300 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
DOFFALOB_03302 1.4e-49 yczJ S biosynthesis
DOFFALOB_03303 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
DOFFALOB_03304 2.8e-176 ydhF S Oxidoreductase
DOFFALOB_03305 0.0 mtlR K transcriptional regulator, MtlR
DOFFALOB_03306 1.4e-294 ydaB IQ acyl-CoA ligase
DOFFALOB_03307 1.1e-99 ydaC Q Methyltransferase domain
DOFFALOB_03308 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DOFFALOB_03309 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
DOFFALOB_03310 5e-104 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
DOFFALOB_03311 6.8e-77 ydaG 1.4.3.5 S general stress protein
DOFFALOB_03312 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
DOFFALOB_03313 5.1e-47 ydzA EGP Major facilitator Superfamily
DOFFALOB_03314 2.5e-74 lrpC K Transcriptional regulator
DOFFALOB_03315 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DOFFALOB_03316 1.9e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
DOFFALOB_03317 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
DOFFALOB_03318 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
DOFFALOB_03319 4.5e-233 ydaM M Glycosyl transferase family group 2
DOFFALOB_03320 8.5e-157 ydaN S Bacterial cellulose synthase subunit
DOFFALOB_03321 6.4e-221 ydaN S Bacterial cellulose synthase subunit
DOFFALOB_03322 0.0 ydaO E amino acid
DOFFALOB_03323 4.6e-79 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
DOFFALOB_03324 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
DOFFALOB_03325 9.4e-40
DOFFALOB_03326 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
DOFFALOB_03328 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
DOFFALOB_03329 3.8e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
DOFFALOB_03331 8.9e-59 ydbB G Cupin domain
DOFFALOB_03332 2.8e-63 ydbC S Domain of unknown function (DUF4937
DOFFALOB_03333 3.2e-155 ydbD P Catalase
DOFFALOB_03334 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
DOFFALOB_03335 2.5e-297 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
DOFFALOB_03336 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
DOFFALOB_03337 6.3e-227 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DOFFALOB_03338 4.4e-181 ydbI S AI-2E family transporter
DOFFALOB_03339 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
DOFFALOB_03340 5.5e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
DOFFALOB_03341 2.7e-52 ydbL
DOFFALOB_03342 3e-220 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
DOFFALOB_03343 1.1e-18 S Fur-regulated basic protein B
DOFFALOB_03344 2.2e-07 S Fur-regulated basic protein A
DOFFALOB_03345 1.9e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DOFFALOB_03346 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
DOFFALOB_03347 4.6e-202 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
DOFFALOB_03348 1.9e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DOFFALOB_03349 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
DOFFALOB_03350 2.1e-82 ydbS S Bacterial PH domain
DOFFALOB_03351 2.2e-263 ydbT S Membrane
DOFFALOB_03352 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
DOFFALOB_03353 2.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DOFFALOB_03354 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
DOFFALOB_03355 2.3e-223 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DOFFALOB_03356 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
DOFFALOB_03357 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
DOFFALOB_03358 1.3e-143 rsbR T Positive regulator of sigma-B
DOFFALOB_03359 5.2e-57 rsbS T antagonist
DOFFALOB_03360 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
DOFFALOB_03361 7.1e-189 rsbU 3.1.3.3 KT phosphatase
DOFFALOB_03362 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
DOFFALOB_03363 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
DOFFALOB_03364 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DOFFALOB_03365 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
DOFFALOB_03369 1.5e-82 ydcG S EVE domain
DOFFALOB_03370 1.6e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
DOFFALOB_03371 0.0 yhgF K COG2183 Transcriptional accessory protein
DOFFALOB_03372 1.6e-84 ydcK S Belongs to the SprT family
DOFFALOB_03380 2.7e-188 luxA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DOFFALOB_03381 2.4e-71 lrpA K transcriptional
DOFFALOB_03382 1.5e-77 lrpB K transcriptional
DOFFALOB_03383 9.6e-100 yddQ 3.5.1.19 Q Isochorismatase family
DOFFALOB_03384 1.5e-143 yddR S Zn-dependent hydrolases of the beta-lactamase fold
DOFFALOB_03385 5e-227 ydeG EGP Major facilitator Superfamily
DOFFALOB_03390 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
DOFFALOB_03391 8.7e-30 cspL K Cold shock
DOFFALOB_03392 6.1e-79 carD K Transcription factor
DOFFALOB_03393 4.6e-35 ydzE EG spore germination
DOFFALOB_03394 1.1e-166 rhaS5 K AraC-like ligand binding domain
DOFFALOB_03395 2.3e-173 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
DOFFALOB_03396 2.5e-166 ydeE K AraC family transcriptional regulator
DOFFALOB_03397 2.2e-265 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
DOFFALOB_03398 3.4e-220 ydeG EGP Major facilitator superfamily
DOFFALOB_03399 2.9e-47 ydeH
DOFFALOB_03400 8.9e-107 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
DOFFALOB_03401 4e-116
DOFFALOB_03402 1.8e-153 ydeK EG -transporter
DOFFALOB_03403 1.5e-274 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
DOFFALOB_03404 4.2e-74 maoC I N-terminal half of MaoC dehydratase
DOFFALOB_03405 8.6e-107 ydeN S Serine hydrolase
DOFFALOB_03406 1.1e-58 K HxlR-like helix-turn-helix
DOFFALOB_03407 1.9e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
DOFFALOB_03408 4.8e-69 ydeP K Transcriptional regulator
DOFFALOB_03409 1.6e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
DOFFALOB_03410 1.2e-195 ydeR EGP Major facilitator Superfamily
DOFFALOB_03411 8.4e-105 ydeS K Transcriptional regulator
DOFFALOB_03412 1.3e-57 arsR K transcriptional
DOFFALOB_03413 5.2e-232 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DOFFALOB_03414 7.2e-149 ydfB J GNAT acetyltransferase
DOFFALOB_03415 1e-162 ydfC EG EamA-like transporter family
DOFFALOB_03416 1.9e-275 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
DOFFALOB_03417 5.9e-117 ydfE S Flavin reductase like domain
DOFFALOB_03418 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
DOFFALOB_03419 1.5e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DOFFALOB_03421 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
DOFFALOB_03422 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DOFFALOB_03423 0.0 ydfJ S drug exporters of the RND superfamily
DOFFALOB_03424 1.9e-177 S Alpha/beta hydrolase family
DOFFALOB_03425 5.9e-118 S Protein of unknown function (DUF554)
DOFFALOB_03426 3.2e-147 K Bacterial transcription activator, effector binding domain
DOFFALOB_03427 1.6e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DOFFALOB_03428 9.6e-112 ydfN C nitroreductase
DOFFALOB_03429 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
DOFFALOB_03430 8.8e-63 mhqP S DoxX
DOFFALOB_03431 1.3e-57 traF CO Thioredoxin
DOFFALOB_03432 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
DOFFALOB_03433 6.3e-29
DOFFALOB_03435 4.4e-118 ydfR S Protein of unknown function (DUF421)
DOFFALOB_03436 5.2e-122 ydfS S Protein of unknown function (DUF421)
DOFFALOB_03437 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
DOFFALOB_03438 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
DOFFALOB_03439 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
DOFFALOB_03440 1.5e-101 K Bacterial regulatory proteins, tetR family
DOFFALOB_03441 7.3e-53 S DoxX-like family
DOFFALOB_03442 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
DOFFALOB_03443 4.2e-308 expZ S ABC transporter
DOFFALOB_03444 4e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
DOFFALOB_03445 4.6e-91 dinB S DinB family
DOFFALOB_03446 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
DOFFALOB_03447 0.0 ydgH S drug exporters of the RND superfamily
DOFFALOB_03448 1e-113 drgA C nitroreductase
DOFFALOB_03449 1.1e-69 ydgJ K Winged helix DNA-binding domain
DOFFALOB_03450 2.5e-209 tcaB EGP Major facilitator Superfamily
DOFFALOB_03451 1.2e-121 ydhB S membrane transporter protein
DOFFALOB_03452 6.5e-122 ydhC K FCD
DOFFALOB_03453 3.3e-244 ydhD M Glycosyl hydrolase
DOFFALOB_03454 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
DOFFALOB_03455 1.9e-127
DOFFALOB_03456 1.4e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
DOFFALOB_03457 4.6e-69 frataxin S Domain of unknown function (DU1801)
DOFFALOB_03459 4.1e-86 K Acetyltransferase (GNAT) domain
DOFFALOB_03460 1.8e-184 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
DOFFALOB_03461 1.7e-99 ydhK M Protein of unknown function (DUF1541)
DOFFALOB_03462 4.6e-200 pbuE EGP Major facilitator Superfamily
DOFFALOB_03463 1.1e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
DOFFALOB_03464 3.5e-52 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
DOFFALOB_03465 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DOFFALOB_03466 2.4e-288 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DOFFALOB_03467 3.9e-133 ydhQ K UTRA
DOFFALOB_03468 9.2e-172 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
DOFFALOB_03469 4.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
DOFFALOB_03470 7.3e-216 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
DOFFALOB_03471 8.7e-78 ydhU P Catalase
DOFFALOB_03472 1.1e-16 ydhU P Manganese containing catalase
DOFFALOB_03475 6.7e-167 ygxA S Nucleotidyltransferase-like
DOFFALOB_03476 1.5e-56 ygzB S UPF0295 protein
DOFFALOB_03477 4e-80 perR P Belongs to the Fur family
DOFFALOB_03478 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
DOFFALOB_03479 1.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
DOFFALOB_03480 8.7e-180 ygaE S Membrane
DOFFALOB_03481 1.8e-301 ygaD V ABC transporter
DOFFALOB_03482 1.3e-104 ygaC J Belongs to the UPF0374 family
DOFFALOB_03483 1.5e-37 ygaB S YgaB-like protein
DOFFALOB_03484 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
DOFFALOB_03485 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DOFFALOB_03486 6.9e-36 yfhS
DOFFALOB_03487 7.8e-212 mutY L A G-specific
DOFFALOB_03488 5.5e-186 yfhP S membrane-bound metal-dependent
DOFFALOB_03489 0.0 yfhO S Bacterial membrane protein YfhO
DOFFALOB_03490 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
DOFFALOB_03491 6.7e-172 yfhM S Alpha beta hydrolase
DOFFALOB_03492 3.5e-51 yfhL S SdpI/YhfL protein family
DOFFALOB_03493 9.2e-92 batE T Bacterial SH3 domain homologues
DOFFALOB_03494 1.3e-44 yfhJ S WVELL protein
DOFFALOB_03495 6.2e-20 sspK S reproduction
DOFFALOB_03496 1.1e-209 yfhI EGP Major facilitator Superfamily
DOFFALOB_03498 9.7e-52 yfhH S Protein of unknown function (DUF1811)
DOFFALOB_03499 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
DOFFALOB_03500 4.9e-173 yfhF S nucleoside-diphosphate sugar epimerase
DOFFALOB_03502 2.1e-25 yfhD S YfhD-like protein
DOFFALOB_03503 3.9e-107 yfhC C nitroreductase
DOFFALOB_03504 1.8e-167 yfhB 5.3.3.17 S PhzF family
DOFFALOB_03505 5.2e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DOFFALOB_03506 3.1e-176 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DOFFALOB_03507 6.2e-182 yfiY P ABC transporter substrate-binding protein
DOFFALOB_03508 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DOFFALOB_03509 3.1e-81 yfiV K transcriptional
DOFFALOB_03510 8.7e-287 yfiU EGP Major facilitator Superfamily
DOFFALOB_03511 3.3e-100 yfiT S Belongs to the metal hydrolase YfiT family
DOFFALOB_03512 5.1e-221 yfiS EGP Major facilitator Superfamily
DOFFALOB_03513 2e-109 yfiR K Transcriptional regulator
DOFFALOB_03514 9e-198 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
DOFFALOB_03515 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
DOFFALOB_03516 8.3e-99 padR K transcriptional
DOFFALOB_03517 4.6e-208 V COG0842 ABC-type multidrug transport system, permease component
DOFFALOB_03518 9.8e-214 V ABC-2 family transporter protein
DOFFALOB_03519 6.2e-171 V ABC transporter, ATP-binding protein
DOFFALOB_03520 3.2e-113 KT LuxR family transcriptional regulator
DOFFALOB_03521 1.1e-214 yxjM T Histidine kinase
DOFFALOB_03523 1.1e-233 S Oxidoreductase
DOFFALOB_03524 8.4e-184 G Xylose isomerase
DOFFALOB_03525 1.8e-262 iolT EGP Major facilitator Superfamily
DOFFALOB_03526 1.5e-177 K AraC-like ligand binding domain
DOFFALOB_03527 5.7e-163 yfiE 1.13.11.2 S glyoxalase
DOFFALOB_03528 9.8e-65 mhqP S DoxX
DOFFALOB_03529 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
DOFFALOB_03530 2.1e-310 yfiB3 V ABC transporter
DOFFALOB_03531 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
DOFFALOB_03532 3.2e-141 glvR K Helix-turn-helix domain, rpiR family
DOFFALOB_03533 9.9e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
DOFFALOB_03534 1.1e-44 yfjA S Belongs to the WXG100 family
DOFFALOB_03535 9.2e-191 yfjB
DOFFALOB_03536 4.1e-144 yfjC
DOFFALOB_03537 1.8e-101 yfjD S Family of unknown function (DUF5381)
DOFFALOB_03538 1.3e-80 S Family of unknown function (DUF5381)
DOFFALOB_03539 4e-56 yfjF S UPF0060 membrane protein
DOFFALOB_03540 1.2e-25 sspH S Belongs to the SspH family
DOFFALOB_03541 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
DOFFALOB_03542 6.4e-257 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
DOFFALOB_03543 2.9e-197 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
DOFFALOB_03544 1e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
DOFFALOB_03545 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
DOFFALOB_03546 3e-29 yfjL
DOFFALOB_03547 3.9e-86 yfjM S Psort location Cytoplasmic, score
DOFFALOB_03548 5.1e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DOFFALOB_03549 1.6e-39 S YfzA-like protein
DOFFALOB_03550 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DOFFALOB_03551 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DOFFALOB_03552 1.7e-184 corA P Mediates influx of magnesium ions
DOFFALOB_03553 4.2e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
DOFFALOB_03554 2.6e-154 pdaA G deacetylase
DOFFALOB_03555 1.1e-26 yfjT
DOFFALOB_03556 5.4e-222 yfkA S YfkB-like domain
DOFFALOB_03557 6e-149 yfkC M Mechanosensitive ion channel
DOFFALOB_03558 1.2e-146 yfkD S YfkD-like protein
DOFFALOB_03559 6.1e-183 cax P COG0387 Ca2 H antiporter
DOFFALOB_03560 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
DOFFALOB_03561 5e-08
DOFFALOB_03562 9.7e-144 yihY S Belongs to the UPF0761 family
DOFFALOB_03563 8.4e-51 yfkI S gas vesicle protein
DOFFALOB_03564 2.2e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DOFFALOB_03565 2.1e-29 yfkK S Belongs to the UPF0435 family
DOFFALOB_03566 6.8e-207 ydiM EGP Major facilitator Superfamily
DOFFALOB_03567 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
DOFFALOB_03568 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
DOFFALOB_03569 1.6e-125 yfkO C nitroreductase
DOFFALOB_03570 1.8e-133 treR K transcriptional
DOFFALOB_03571 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
DOFFALOB_03572 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
DOFFALOB_03573 1.5e-283 yfkQ EG Spore germination protein
DOFFALOB_03574 5.1e-207 yfkR S spore germination
DOFFALOB_03576 1.6e-194 E Spore germination protein
DOFFALOB_03577 3.2e-256 agcS_1 E Sodium alanine symporter
DOFFALOB_03578 6e-67 yhdN S Domain of unknown function (DUF1992)
DOFFALOB_03579 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
DOFFALOB_03580 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
DOFFALOB_03581 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
DOFFALOB_03582 2.4e-50 yflH S Protein of unknown function (DUF3243)
DOFFALOB_03583 4.1e-19 yflI
DOFFALOB_03584 4e-18 yflJ S Protein of unknown function (DUF2639)
DOFFALOB_03585 9e-124 yflK S protein conserved in bacteria
DOFFALOB_03586 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
DOFFALOB_03587 1.3e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
DOFFALOB_03588 5.5e-152 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
DOFFALOB_03589 8.5e-227 citM C Citrate transporter
DOFFALOB_03591 3e-181 yflP S Tripartite tricarboxylate transporter family receptor
DOFFALOB_03592 8.9e-119 citT T response regulator
DOFFALOB_03593 1e-290 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
DOFFALOB_03594 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
DOFFALOB_03595 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
DOFFALOB_03596 7.6e-58 yflT S Heat induced stress protein YflT
DOFFALOB_03597 2.9e-24 S Protein of unknown function (DUF3212)
DOFFALOB_03598 3.4e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
DOFFALOB_03599 4.3e-170 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DOFFALOB_03600 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DOFFALOB_03601 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
DOFFALOB_03602 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
DOFFALOB_03603 7.7e-214 G Major Facilitator Superfamily
DOFFALOB_03604 8.5e-190 yfmJ S N-terminal domain of oxidoreductase
DOFFALOB_03605 7.5e-82 yfmK 2.3.1.128 K acetyltransferase
DOFFALOB_03606 6.3e-202 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
DOFFALOB_03607 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
DOFFALOB_03608 1.5e-209 yfmO EGP Major facilitator Superfamily
DOFFALOB_03609 2.8e-70 yfmP K transcriptional
DOFFALOB_03610 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
DOFFALOB_03611 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
DOFFALOB_03612 1.1e-113 yfmS NT chemotaxis protein
DOFFALOB_03613 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
DOFFALOB_03614 1.3e-241 yfnA E amino acid
DOFFALOB_03615 7.8e-134 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
DOFFALOB_03616 2e-206 fsr P COG0477 Permeases of the major facilitator superfamily
DOFFALOB_03617 3.5e-190 yfnD M Nucleotide-diphospho-sugar transferase
DOFFALOB_03618 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
DOFFALOB_03619 3.8e-181 yfnF M Nucleotide-diphospho-sugar transferase
DOFFALOB_03620 1.9e-172 yfnG 4.2.1.45 M dehydratase
DOFFALOB_03621 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
DOFFALOB_03622 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
DOFFALOB_03623 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
DOFFALOB_03624 3.6e-199 yetN S Protein of unknown function (DUF3900)
DOFFALOB_03625 7.8e-213 yetM CH FAD binding domain
DOFFALOB_03626 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
DOFFALOB_03627 5.4e-159 yetK EG EamA-like transporter family
DOFFALOB_03628 5.3e-105 yetJ S Belongs to the BI1 family
DOFFALOB_03629 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
DOFFALOB_03630 4.4e-43 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
DOFFALOB_03631 2.2e-89 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
DOFFALOB_03632 2.2e-34
DOFFALOB_03633 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DOFFALOB_03634 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
DOFFALOB_03635 6.1e-123 yetF S membrane
DOFFALOB_03636 3.3e-258 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
DOFFALOB_03637 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
DOFFALOB_03638 1.3e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
DOFFALOB_03639 9.6e-291 lplA G Bacterial extracellular solute-binding protein
DOFFALOB_03640 0.0 yetA
DOFFALOB_03641 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
DOFFALOB_03642 3e-124 yesY E GDSL-like Lipase/Acylhydrolase
DOFFALOB_03643 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
DOFFALOB_03644 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
DOFFALOB_03645 1e-113 yesV S Protein of unknown function, DUF624
DOFFALOB_03646 8.9e-132 yesU S Domain of unknown function (DUF1961)
DOFFALOB_03647 3.8e-133 E GDSL-like Lipase/Acylhydrolase
DOFFALOB_03648 0.0 yesS K Transcriptional regulator
DOFFALOB_03649 1.6e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
DOFFALOB_03650 1.3e-165 yesQ P Binding-protein-dependent transport system inner membrane component
DOFFALOB_03651 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
DOFFALOB_03652 5e-248 yesO G Bacterial extracellular solute-binding protein
DOFFALOB_03653 2.9e-204 yesN K helix_turn_helix, arabinose operon control protein
DOFFALOB_03654 0.0 yesM 2.7.13.3 T Histidine kinase
DOFFALOB_03655 4.4e-104 yesL S Protein of unknown function, DUF624
DOFFALOB_03657 4.2e-103 yesJ K Acetyltransferase (GNAT) family
DOFFALOB_03658 5.2e-104 cotJC P Spore Coat
DOFFALOB_03659 1.5e-45 cotJB S CotJB protein
DOFFALOB_03660 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
DOFFALOB_03661 2.2e-159 yesF GM NAD(P)H-binding
DOFFALOB_03662 9.7e-82 yesE S SnoaL-like domain
DOFFALOB_03663 1.2e-103 dhaR3 K Transcriptional regulator
DOFFALOB_03665 9.4e-127 yeeN K transcriptional regulatory protein
DOFFALOB_03667 5.5e-214 S Tetratricopeptide repeat
DOFFALOB_03668 1.8e-192 3.4.24.40 CO amine dehydrogenase activity
DOFFALOB_03669 0.0 L nucleic acid phosphodiester bond hydrolysis
DOFFALOB_03670 5.5e-83 S Protein of unknown function, DUF600
DOFFALOB_03671 6.2e-31 S Colicin immunity protein / pyocin immunity protein
DOFFALOB_03673 1.2e-211 pstS P T5orf172
DOFFALOB_03674 0.0 yeeB L DEAD-like helicases superfamily
DOFFALOB_03675 0.0 yeeA V Type II restriction enzyme, methylase subunits
DOFFALOB_03676 3.2e-53 L Resolvase, N terminal domain
DOFFALOB_03677 3.2e-98 L Recombinase
DOFFALOB_03678 1.2e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DOFFALOB_03679 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
DOFFALOB_03680 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DOFFALOB_03681 4e-156 yerO K Transcriptional regulator
DOFFALOB_03682 3.4e-269 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DOFFALOB_03683 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DOFFALOB_03684 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DOFFALOB_03685 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DOFFALOB_03686 1.6e-123 sapB S MgtC SapB transporter
DOFFALOB_03687 1.1e-197 yerI S homoserine kinase type II (protein kinase fold)
DOFFALOB_03688 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
DOFFALOB_03689 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DOFFALOB_03690 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
DOFFALOB_03691 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
DOFFALOB_03693 3.2e-305 yerD 1.4.7.1 E Belongs to the glutamate synthase family
DOFFALOB_03694 4.8e-51 yerC S protein conserved in bacteria
DOFFALOB_03695 3e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
DOFFALOB_03696 0.0 yerA 3.5.4.2 F adenine deaminase
DOFFALOB_03697 2.7e-27 S Protein of unknown function (DUF2892)
DOFFALOB_03698 2.3e-232 yjeH E Amino acid permease
DOFFALOB_03699 3.5e-73 K helix_turn_helix ASNC type
DOFFALOB_03700 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
DOFFALOB_03701 3.5e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
DOFFALOB_03702 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DOFFALOB_03703 3.2e-176 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
DOFFALOB_03704 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DOFFALOB_03705 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DOFFALOB_03706 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DOFFALOB_03707 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DOFFALOB_03708 1.2e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
DOFFALOB_03709 2.1e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DOFFALOB_03710 7e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DOFFALOB_03711 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DOFFALOB_03712 8e-28 yebG S NETI protein
DOFFALOB_03713 4e-93 yebE S UPF0316 protein
DOFFALOB_03715 1.1e-118 yebC M Membrane
DOFFALOB_03716 6e-212 pbuG S permease
DOFFALOB_03717 9.8e-256 S Domain of unknown function (DUF4179)
DOFFALOB_03718 2e-89 K Belongs to the sigma-70 factor family. ECF subfamily
DOFFALOB_03719 3.7e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
DOFFALOB_03720 0.0 yebA E COG1305 Transglutaminase-like enzymes
DOFFALOB_03721 9.5e-225 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
DOFFALOB_03722 1.6e-177 yeaC S COG0714 MoxR-like ATPases
DOFFALOB_03723 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DOFFALOB_03724 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
DOFFALOB_03725 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
DOFFALOB_03726 3.3e-175 yeaA S Protein of unknown function (DUF4003)
DOFFALOB_03727 8.4e-156 ydjP I Alpha/beta hydrolase family
DOFFALOB_03728 1.4e-34 ydjO S Cold-inducible protein YdjO
DOFFALOB_03730 2.3e-150 ydjN U Involved in the tonB-independent uptake of proteins
DOFFALOB_03731 4.5e-64 ydjM M Lytic transglycolase
DOFFALOB_03732 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
DOFFALOB_03733 2.7e-258 iolT EGP Major facilitator Superfamily
DOFFALOB_03734 4.7e-196 S Ion transport 2 domain protein
DOFFALOB_03735 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
DOFFALOB_03736 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
DOFFALOB_03737 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DOFFALOB_03738 5.1e-114 pspA KT Phage shock protein A
DOFFALOB_03739 1.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
DOFFALOB_03740 7.1e-256 gutA G MFS/sugar transport protein
DOFFALOB_03741 3.8e-201 gutB 1.1.1.14 E Dehydrogenase
DOFFALOB_03742 0.0 K NB-ARC domain
DOFFALOB_03743 1.1e-08 ydjC S Abhydrolase domain containing 18
DOFFALOB_03744 4.9e-257 J LlaJI restriction endonuclease
DOFFALOB_03745 1.2e-199 V AAA domain (dynein-related subfamily)
DOFFALOB_03747 1.6e-232 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
DOFFALOB_03748 1.1e-250 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
DOFFALOB_03749 6.4e-66 KL Phage plasmid primase P4 family
DOFFALOB_03751 1.2e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DOFFALOB_03752 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DOFFALOB_03753 7.9e-129 ydiL S CAAX protease self-immunity
DOFFALOB_03754 2.9e-27 ydiK S Domain of unknown function (DUF4305)
DOFFALOB_03755 8.4e-126 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DOFFALOB_03756 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
DOFFALOB_03757 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DOFFALOB_03758 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
DOFFALOB_03759 0.0 ydiF S ABC transporter
DOFFALOB_03760 3.6e-188 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DOFFALOB_03761 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
DOFFALOB_03762 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
DOFFALOB_03763 9.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
DOFFALOB_03764 4.6e-185 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DOFFALOB_03766 7.8e-08
DOFFALOB_03767 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DOFFALOB_03768 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DOFFALOB_03769 1.8e-37 yaaB S Domain of unknown function (DUF370)
DOFFALOB_03770 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DOFFALOB_03771 2.4e-33 yaaA S S4 domain
DOFFALOB_03772 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DOFFALOB_03773 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DOFFALOB_03774 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
DOFFALOB_03775 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DOFFALOB_03776 6.5e-108 jag S single-stranded nucleic acid binding R3H
DOFFALOB_03777 3.7e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DOFFALOB_03778 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
DOFFALOB_03779 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
DOFFALOB_03780 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
DOFFALOB_03781 1.9e-74 S Bacterial PH domain
DOFFALOB_03782 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
DOFFALOB_03783 2.1e-149 spo0J K Belongs to the ParB family
DOFFALOB_03784 1.6e-111 yyaC S Sporulation protein YyaC
DOFFALOB_03785 8.1e-177 yyaD S Membrane
DOFFALOB_03786 2.3e-33 yyzM S protein conserved in bacteria
DOFFALOB_03787 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DOFFALOB_03788 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DOFFALOB_03789 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
DOFFALOB_03790 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DOFFALOB_03791 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DOFFALOB_03792 8.1e-145 xth 3.1.11.2 L exodeoxyribonuclease III
DOFFALOB_03793 3.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
DOFFALOB_03794 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DOFFALOB_03795 5.1e-96 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
DOFFALOB_03796 3.8e-246 EGP Major facilitator superfamily
DOFFALOB_03797 9.5e-169 yyaK S CAAX protease self-immunity
DOFFALOB_03798 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
DOFFALOB_03799 3.3e-161 yyaM EG EamA-like transporter family
DOFFALOB_03800 5.1e-61 yyaN K MerR HTH family regulatory protein
DOFFALOB_03801 9.7e-44 yyaL O Highly conserved protein containing a thioredoxin domain
DOFFALOB_03802 1.7e-249 tetL EGP Major facilitator Superfamily
DOFFALOB_03803 1.7e-107 yyaP 1.5.1.3 H RibD C-terminal domain
DOFFALOB_03804 5.4e-67 yyaQ S YjbR
DOFFALOB_03805 5.4e-100 yyaR K Acetyltransferase (GNAT) domain
DOFFALOB_03806 1.5e-101 yyaS S Membrane
DOFFALOB_03807 5.9e-79 yjcF S Acetyltransferase (GNAT) domain
DOFFALOB_03808 5.6e-77 yybA 2.3.1.57 K transcriptional
DOFFALOB_03809 3e-127 S Metallo-beta-lactamase superfamily
DOFFALOB_03810 2.7e-77 yybC
DOFFALOB_03811 2e-79 yjcF S Acetyltransferase (GNAT) domain
DOFFALOB_03812 2.1e-165 yybE K Transcriptional regulator
DOFFALOB_03813 3.2e-220 ynfM EGP Major facilitator Superfamily
DOFFALOB_03814 3e-124 yybG S Pentapeptide repeat-containing protein
DOFFALOB_03815 5.9e-67 yybH S SnoaL-like domain
DOFFALOB_03816 6.2e-132
DOFFALOB_03817 2.6e-115 V ATPases associated with a variety of cellular activities
DOFFALOB_03818 2e-127 S Protein of unknown function (DUF2705)
DOFFALOB_03819 9e-122
DOFFALOB_03820 4.1e-125
DOFFALOB_03821 1.3e-78 yybN S Protein of unknown function (DUF2712)
DOFFALOB_03822 1e-16
DOFFALOB_03823 2.3e-240 yybO G COG0477 Permeases of the major facilitator superfamily
DOFFALOB_03825 1.3e-70
DOFFALOB_03826 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
DOFFALOB_03827 1.4e-68 ydeP3 K Transcriptional regulator
DOFFALOB_03828 3.9e-84 cotF M Spore coat protein
DOFFALOB_03830 2.9e-160 yybS S membrane
DOFFALOB_03831 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
DOFFALOB_03832 2.2e-73 rplI J binds to the 23S rRNA
DOFFALOB_03833 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DOFFALOB_03834 8.4e-221 yeaN P COG2807 Cyanate permease
DOFFALOB_03835 1.9e-15 yycC K YycC-like protein
DOFFALOB_03837 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
DOFFALOB_03838 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
DOFFALOB_03839 8e-78 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DOFFALOB_03840 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DOFFALOB_03845 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DOFFALOB_03846 0.0 vicK 2.7.13.3 T Histidine kinase
DOFFALOB_03847 3.6e-260 yycH S protein conserved in bacteria
DOFFALOB_03848 7.3e-155 yycI S protein conserved in bacteria
DOFFALOB_03849 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
DOFFALOB_03850 8.4e-221 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DOFFALOB_03851 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
DOFFALOB_03852 1.7e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
DOFFALOB_03853 9.7e-261 rocE E amino acid
DOFFALOB_03854 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
DOFFALOB_03856 5e-188 S aspartate phosphatase
DOFFALOB_03857 3.1e-86 yycN 2.3.1.128 K Acetyltransferase
DOFFALOB_03858 5.8e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
DOFFALOB_03859 1.6e-221 yycP
DOFFALOB_03860 2.1e-33 yycQ S Protein of unknown function (DUF2651)
DOFFALOB_03862 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
DOFFALOB_03863 4.2e-71
DOFFALOB_03864 1.1e-09 S YyzF-like protein
DOFFALOB_03865 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DOFFALOB_03866 7.3e-280 S Calcineurin-like phosphoesterase
DOFFALOB_03867 3.5e-65
DOFFALOB_03868 0.0 S Uncharacterised protein conserved in bacteria (DUF2326)
DOFFALOB_03869 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
DOFFALOB_03870 8e-12
DOFFALOB_03871 7.7e-185 S Radical SAM superfamily
DOFFALOB_03872 8.4e-134 yydH O Peptidase M50
DOFFALOB_03873 1.8e-110 prrC P ABC transporter
DOFFALOB_03874 3.3e-119 S ABC-2 family transporter protein
DOFFALOB_03875 7.6e-13
DOFFALOB_03876 1.3e-128 yydK K Transcriptional regulator
DOFFALOB_03877 2.3e-34 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
DOFFALOB_03878 6.4e-292 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DOFFALOB_03879 3.8e-287 ahpF O Alkyl hydroperoxide reductase
DOFFALOB_03880 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
DOFFALOB_03881 3.8e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DOFFALOB_03882 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
DOFFALOB_03883 4.6e-304 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
DOFFALOB_03884 7.3e-127 gntR K transcriptional
DOFFALOB_03885 7e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
DOFFALOB_03886 1.3e-193 yxaB GM Polysaccharide pyruvyl transferase
DOFFALOB_03887 2.6e-118 yxaC M effector of murein hydrolase
DOFFALOB_03888 5.2e-50 S LrgA family
DOFFALOB_03889 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
DOFFALOB_03890 2.3e-201 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
DOFFALOB_03891 7.1e-101 yxaF K Transcriptional regulator
DOFFALOB_03892 1.5e-199 yxaG 1.13.11.24 S AraC-like ligand binding domain
DOFFALOB_03893 1.4e-228 P Protein of unknown function (DUF418)
DOFFALOB_03894 1.1e-75 yxaI S membrane protein domain
DOFFALOB_03895 3.5e-65 S Family of unknown function (DUF5391)
DOFFALOB_03896 6.8e-93 S PQQ-like domain
DOFFALOB_03897 7.6e-214 yxaM U MFS_1 like family
DOFFALOB_03898 0.0 asnB 6.3.5.4 E Asparagine synthase
DOFFALOB_03899 1.1e-86 yxnB
DOFFALOB_03900 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
DOFFALOB_03901 3.3e-127 yxbB Q Met-10+ like-protein
DOFFALOB_03902 4.4e-10
DOFFALOB_03904 2.2e-72
DOFFALOB_03905 1.4e-13 repE K Primase C terminal 1 (PriCT-1)
DOFFALOB_03906 2.8e-110 yukA S COG0433 Predicted ATPase
DOFFALOB_03911 3.7e-14 S Conjugative transposon protein TcpC
DOFFALOB_03913 5.2e-13 S TcpE family
DOFFALOB_03914 1.7e-133 yddE S AAA-like domain
DOFFALOB_03915 2.8e-11 M Membrane
DOFFALOB_03917 2.2e-13 S response regulator aspartate phosphatase
DOFFALOB_03920 5.3e-51 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DOFFALOB_03921 7.6e-105 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
DOFFALOB_03925 2.3e-13 L Psort location Cytoplasmic, score 8.96
DOFFALOB_03926 3.3e-25
DOFFALOB_03927 3.3e-94 S Histidine kinase
DOFFALOB_03931 1.2e-78 S response regulator aspartate phosphatase
DOFFALOB_03933 4.4e-24 V VanZ like family
DOFFALOB_03935 8.1e-26
DOFFALOB_03937 1e-19 S YolD-like protein
DOFFALOB_03940 6.2e-131 L Phage integrase, N-terminal SAM-like domain
DOFFALOB_03942 4.4e-140 dinG 3.6.4.12 KL helicase involved in DNA repair and perhaps also replication
DOFFALOB_03944 6.6e-15 3.1.12.1 L TIGRFAM CRISPR-associated protein Cas4
DOFFALOB_03945 4e-12 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
DOFFALOB_03946 2.3e-48 3.1.31.1 L Staphylococcal nuclease homologues
DOFFALOB_03947 3.8e-24 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DOFFALOB_03953 3.9e-30 3.2.1.4 GH5,GH9 S metallopeptidase activity
DOFFALOB_03957 2.1e-12 flpE D NUBPL iron-transfer P-loop NTPase
DOFFALOB_03958 4.7e-31 cpaF U Type II/IV secretion system protein
DOFFALOB_03966 8.7e-77 M Transglycosylase SLT domain
DOFFALOB_03968 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
DOFFALOB_03969 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
DOFFALOB_03970 1.2e-84 gerD
DOFFALOB_03971 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
DOFFALOB_03972 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
DOFFALOB_03973 9.7e-66 ybaK S Protein of unknown function (DUF2521)
DOFFALOB_03974 8.2e-145 ybaJ Q Methyltransferase domain
DOFFALOB_03975 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
DOFFALOB_03976 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DOFFALOB_03977 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DOFFALOB_03978 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DOFFALOB_03979 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DOFFALOB_03980 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DOFFALOB_03981 3.6e-58 rplQ J Ribosomal protein L17
DOFFALOB_03982 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DOFFALOB_03983 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DOFFALOB_03984 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DOFFALOB_03985 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
DOFFALOB_03986 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DOFFALOB_03987 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
DOFFALOB_03988 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DOFFALOB_03989 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DOFFALOB_03990 1.8e-72 rplO J binds to the 23S rRNA
DOFFALOB_03991 1.9e-23 rpmD J Ribosomal protein L30
DOFFALOB_03992 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DOFFALOB_03993 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DOFFALOB_03994 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DOFFALOB_03995 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DOFFALOB_03996 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DOFFALOB_03997 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DOFFALOB_03998 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DOFFALOB_03999 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DOFFALOB_04000 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DOFFALOB_04001 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
DOFFALOB_04002 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DOFFALOB_04003 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DOFFALOB_04004 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DOFFALOB_04005 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DOFFALOB_04006 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DOFFALOB_04007 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DOFFALOB_04008 3e-105 rplD J Forms part of the polypeptide exit tunnel
DOFFALOB_04009 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DOFFALOB_04010 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
DOFFALOB_04011 9.1e-186 ybaC 3.4.11.5 S Alpha/beta hydrolase family
DOFFALOB_04012 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DOFFALOB_04013 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DOFFALOB_04014 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DOFFALOB_04015 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DOFFALOB_04016 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
DOFFALOB_04017 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DOFFALOB_04018 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DOFFALOB_04019 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
DOFFALOB_04020 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DOFFALOB_04021 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DOFFALOB_04022 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DOFFALOB_04023 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DOFFALOB_04024 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
DOFFALOB_04025 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
DOFFALOB_04026 4.4e-115 sigH K Belongs to the sigma-70 factor family
DOFFALOB_04027 1.2e-88 yacP S RNA-binding protein containing a PIN domain
DOFFALOB_04028 1.2e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DOFFALOB_04029 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DOFFALOB_04030 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
DOFFALOB_04031 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
DOFFALOB_04032 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DOFFALOB_04033 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
DOFFALOB_04034 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
DOFFALOB_04035 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
DOFFALOB_04036 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DOFFALOB_04037 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DOFFALOB_04038 0.0 clpC O Belongs to the ClpA ClpB family
DOFFALOB_04039 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
DOFFALOB_04040 4.7e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
DOFFALOB_04041 2.9e-76 ctsR K Belongs to the CtsR family
DOFFALOB_04042 3.4e-31 csfB S Inhibitor of sigma-G Gin
DOFFALOB_04043 4.7e-103 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
DOFFALOB_04044 4.5e-203 yaaN P Belongs to the TelA family
DOFFALOB_04045 1.1e-275 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
DOFFALOB_04046 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DOFFALOB_04047 2.2e-54 yaaQ S protein conserved in bacteria
DOFFALOB_04048 1.5e-71 yaaR S protein conserved in bacteria
DOFFALOB_04049 2.2e-182 holB 2.7.7.7 L DNA polymerase III
DOFFALOB_04050 2.1e-146 yaaT S stage 0 sporulation protein
DOFFALOB_04051 4.8e-31 yabA L Involved in initiation control of chromosome replication
DOFFALOB_04052 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
DOFFALOB_04053 1.5e-49 yazA L endonuclease containing a URI domain
DOFFALOB_04054 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DOFFALOB_04055 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
DOFFALOB_04056 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DOFFALOB_04057 1.8e-144 tatD L hydrolase, TatD
DOFFALOB_04058 4.3e-194 rpfB GH23 T protein conserved in bacteria
DOFFALOB_04059 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DOFFALOB_04060 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DOFFALOB_04061 1.6e-136 yabG S peptidase
DOFFALOB_04062 7.8e-39 veg S protein conserved in bacteria
DOFFALOB_04063 8.3e-27 sspF S DNA topological change
DOFFALOB_04064 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DOFFALOB_04065 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
DOFFALOB_04066 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
DOFFALOB_04067 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
DOFFALOB_04068 6.6e-230 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DOFFALOB_04069 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DOFFALOB_04070 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DOFFALOB_04071 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DOFFALOB_04072 2.4e-39 yabK S Peptide ABC transporter permease
DOFFALOB_04073 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DOFFALOB_04074 1.5e-92 spoVT K stage V sporulation protein
DOFFALOB_04075 2.4e-287 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
DOFFALOB_04076 2.7e-245 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
DOFFALOB_04077 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
DOFFALOB_04078 1.5e-49 yabP S Sporulation protein YabP
DOFFALOB_04079 3.9e-108 yabQ S spore cortex biosynthesis protein
DOFFALOB_04080 1.1e-44 divIC D Septum formation initiator
DOFFALOB_04081 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
DOFFALOB_04084 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
DOFFALOB_04085 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
DOFFALOB_04086 6.7e-187 KLT serine threonine protein kinase
DOFFALOB_04087 3.5e-274 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DOFFALOB_04088 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
DOFFALOB_04089 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DOFFALOB_04090 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DOFFALOB_04091 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DOFFALOB_04092 3.1e-153 yacD 5.2.1.8 O peptidyl-prolyl isomerase
DOFFALOB_04093 8.9e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
DOFFALOB_04094 4.7e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DOFFALOB_04095 1.5e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
DOFFALOB_04096 1.6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
DOFFALOB_04097 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DOFFALOB_04098 8.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DOFFALOB_04099 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DOFFALOB_04100 4.1e-30 yazB K transcriptional
DOFFALOB_04101 3.7e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DOFFALOB_04102 1.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
DOFFALOB_04106 2e-08
DOFFALOB_04107 1.4e-09 lexA 3.4.21.88 K LexA DNA binding domain
DOFFALOB_04108 1.3e-08 K Transcriptional regulator
DOFFALOB_04109 3e-35 S YolD-like protein
DOFFALOB_04111 1.1e-156 S Aspartate phosphatase response regulator
DOFFALOB_04112 6.2e-185 A Pre-toxin TG
DOFFALOB_04113 1.7e-39
DOFFALOB_04114 1e-123 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
DOFFALOB_04115 7.9e-31 xhlB S SPP1 phage holin
DOFFALOB_04116 2.8e-34 xhlA S Haemolysin XhlA
DOFFALOB_04117 4.9e-149 xepA
DOFFALOB_04118 6.7e-20
DOFFALOB_04119 1.8e-43 xkdW S XkdW protein
DOFFALOB_04120 5.2e-163
DOFFALOB_04121 2.5e-35
DOFFALOB_04122 6.7e-99 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
DOFFALOB_04123 5.5e-184 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
DOFFALOB_04124 2.5e-66 xkdS S Protein of unknown function (DUF2634)
DOFFALOB_04125 1e-30 xkdR S Protein of unknown function (DUF2577)
DOFFALOB_04126 2.7e-177 yqbQ 3.2.1.96 G NLP P60 protein
DOFFALOB_04127 4.3e-110 xkdP S Lysin motif
DOFFALOB_04128 0.0 xkdO L Transglycosylase SLT domain
DOFFALOB_04129 5.5e-16
DOFFALOB_04130 2.3e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
DOFFALOB_04131 7.4e-74 xkdM S Phage tail tube protein
DOFFALOB_04132 1.2e-242 xkdK S Phage tail sheath C-terminal domain
DOFFALOB_04133 2e-23
DOFFALOB_04134 4.3e-66
DOFFALOB_04135 3.1e-84 S Bacteriophage HK97-gp10, putative tail-component
DOFFALOB_04136 4.4e-56 yqbH S Domain of unknown function (DUF3599)
DOFFALOB_04137 1.5e-46 S Protein of unknown function (DUF3199)
DOFFALOB_04138 2.1e-22 S YqbF, hypothetical protein domain
DOFFALOB_04139 1.1e-146 xkdG S Phage capsid family
DOFFALOB_04140 1.8e-95 yqbD 2.1.1.72 L Putative phage serine protease XkdF
DOFFALOB_04142 2.2e-144 S Phage Mu protein F like protein
DOFFALOB_04143 2.2e-250 yqbA S portal protein
DOFFALOB_04144 2.7e-233 S phage terminase, large subunit
DOFFALOB_04145 4.7e-61
DOFFALOB_04146 2.8e-14 yfbU S Belongs to the UPF0304 family
DOFFALOB_04147 8.2e-30
DOFFALOB_04148 2.3e-99 S Domain of unknown function (DUF4145)
DOFFALOB_04149 3e-126 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
DOFFALOB_04150 4.1e-55 K DNA binding
DOFFALOB_04156 3.4e-38
DOFFALOB_04157 5e-25
DOFFALOB_04160 1.9e-30
DOFFALOB_04164 6e-70
DOFFALOB_04165 3.5e-48 3.1.22.4
DOFFALOB_04168 5e-179 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
DOFFALOB_04169 2.2e-07 S Loader and inhibitor of phage G40P
DOFFALOB_04170 4e-27 L primosome component and related proteins
DOFFALOB_04172 4.1e-103 S Metallo-beta-lactamase superfamily
DOFFALOB_04173 4.5e-115 recT L RecT family
DOFFALOB_04174 3.7e-165 D nuclear chromosome segregation
DOFFALOB_04178 4.3e-44
DOFFALOB_04179 2.5e-10 S Helix-turn-helix domain
DOFFALOB_04180 7e-15 ropB K sequence-specific DNA binding
DOFFALOB_04181 5.1e-19 K Cro/C1-type HTH DNA-binding domain
DOFFALOB_04182 4.5e-13
DOFFALOB_04183 4.3e-36 xkdA E IrrE N-terminal-like domain
DOFFALOB_04184 2.2e-80 L Phage integrase, N-terminal SAM-like domain
DOFFALOB_04187 1.4e-100 yqaB E IrrE N-terminal-like domain
DOFFALOB_04188 1e-101 adk 2.7.4.3 F adenylate kinase activity
DOFFALOB_04190 1.1e-56 K sequence-specific DNA binding
DOFFALOB_04191 6.5e-37 K Helix-turn-helix XRE-family like proteins
DOFFALOB_04193 1.2e-103
DOFFALOB_04197 1.5e-180 yqaJ L YqaJ-like viral recombinase domain
DOFFALOB_04198 2.5e-155 recT L RecT family
DOFFALOB_04199 1e-122 3.1.3.16 L DnaD domain protein
DOFFALOB_04200 5.9e-168 xkdC L IstB-like ATP binding protein
DOFFALOB_04202 7.2e-74 rusA L Endodeoxyribonuclease RusA
DOFFALOB_04203 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
DOFFALOB_04204 1.6e-166
DOFFALOB_04205 6.5e-81 L Transposase
DOFFALOB_04207 6.3e-107 yqaS L DNA packaging
DOFFALOB_04208 2.4e-253 S phage terminase, large subunit
DOFFALOB_04209 5.9e-296 yqbA S portal protein
DOFFALOB_04210 5.7e-169 S Phage Mu protein F like protein
DOFFALOB_04211 2e-115
DOFFALOB_04212 5.1e-128 yqbD 2.1.1.72 L Putative phage serine protease XkdF
DOFFALOB_04213 1.9e-167 xkdG S Phage capsid family
DOFFALOB_04214 3.6e-51 S YqbF, hypothetical protein domain
DOFFALOB_04215 2.1e-67 S Protein of unknown function (DUF3199)
DOFFALOB_04216 6.7e-65 yqbH S Domain of unknown function (DUF3599)
DOFFALOB_04217 4.3e-94 S Bacteriophage HK97-gp10, putative tail-component
DOFFALOB_04218 1.4e-77
DOFFALOB_04219 3.2e-26
DOFFALOB_04220 5.5e-256 xkdK S Phage tail sheath C-terminal domain
DOFFALOB_04221 3.6e-76 xkdM S Phage tail tube protein
DOFFALOB_04223 1.8e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
DOFFALOB_04224 0.0 xkdO L Transglycosylase SLT domain
DOFFALOB_04225 9e-114 xkdP S Lysin motif
DOFFALOB_04226 6.9e-181 yqbQ 3.2.1.96 G NLP P60 protein
DOFFALOB_04227 1.8e-38 xkdR S Protein of unknown function (DUF2577)
DOFFALOB_04228 9.6e-71 xkdS S Protein of unknown function (DUF2634)
DOFFALOB_04229 1.1e-67 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
DOFFALOB_04230 4.8e-114 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
DOFFALOB_04231 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
DOFFALOB_04232 9.6e-40
DOFFALOB_04233 2e-221
DOFFALOB_04234 4.1e-56 xkdW S XkdW protein
DOFFALOB_04235 1.3e-23
DOFFALOB_04236 4.8e-165 xepA
DOFFALOB_04237 2.6e-68 S Bacteriophage holin family
DOFFALOB_04238 1.1e-144 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
DOFFALOB_04240 5e-60
DOFFALOB_04242 1.1e-104 S Suppressor of fused protein (SUFU)
DOFFALOB_04243 3.8e-277 A Pre-toxin TG
DOFFALOB_04246 1.6e-96 S Tetratricopeptide repeat
DOFFALOB_04247 1.1e-152 yqcI S YqcI/YcgG family
DOFFALOB_04248 1.6e-54 arsR K ArsR family transcriptional regulator
DOFFALOB_04249 2.8e-73 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DOFFALOB_04250 6e-183 arsB 1.20.4.1 P Arsenic resistance protein
DOFFALOB_04251 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
DOFFALOB_04252 1.4e-281 cisA2 L Recombinase
DOFFALOB_04253 2.7e-182 yaaC S YaaC-like Protein
DOFFALOB_04254 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
DOFFALOB_04255 5.2e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
DOFFALOB_04256 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DOFFALOB_04257 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DOFFALOB_04258 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DOFFALOB_04259 1.3e-09
DOFFALOB_04260 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
DOFFALOB_04261 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
DOFFALOB_04262 5.6e-215 yaaH M Glycoside Hydrolase Family
DOFFALOB_04263 2.4e-98 yaaI Q COG1335 Amidases related to nicotinamidase
DOFFALOB_04264 1e-84 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DOFFALOB_04265 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DOFFALOB_04266 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DOFFALOB_04267 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DOFFALOB_04268 7.9e-32 yaaL S Protein of unknown function (DUF2508)
DOFFALOB_04269 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
DOFFALOB_04270 3.4e-39 S COG NOG14552 non supervised orthologous group
DOFFALOB_04275 2e-08
DOFFALOB_04279 1.3e-33 ybfA S response to radiation

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)