ORF_ID e_value Gene_name EC_number CAZy COGs Description
EFDNPGAD_00001 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EFDNPGAD_00002 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
EFDNPGAD_00003 2.8e-64 yngL S Protein of unknown function (DUF1360)
EFDNPGAD_00004 1.3e-306 yngK T Glycosyl hydrolase-like 10
EFDNPGAD_00005 1.8e-31 S Family of unknown function (DUF5367)
EFDNPGAD_00006 4.4e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
EFDNPGAD_00007 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EFDNPGAD_00008 3e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
EFDNPGAD_00009 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
EFDNPGAD_00010 8e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
EFDNPGAD_00011 2.2e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
EFDNPGAD_00012 6.3e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EFDNPGAD_00013 1.9e-233 nrnB S phosphohydrolase (DHH superfamily)
EFDNPGAD_00014 5.5e-104 yngC S membrane-associated protein
EFDNPGAD_00015 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
EFDNPGAD_00016 2.4e-80 yngA S membrane
EFDNPGAD_00017 4.4e-299 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
EFDNPGAD_00018 3.7e-251 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
EFDNPGAD_00020 2.4e-297 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
EFDNPGAD_00021 8.2e-252 agcS E Sodium alanine symporter
EFDNPGAD_00022 1.3e-57 ynfC
EFDNPGAD_00023 2.3e-12
EFDNPGAD_00024 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EFDNPGAD_00025 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EFDNPGAD_00026 6.6e-69 yccU S CoA-binding protein
EFDNPGAD_00027 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EFDNPGAD_00028 4.1e-49 yneR S Belongs to the HesB IscA family
EFDNPGAD_00029 1.3e-53 yneQ
EFDNPGAD_00030 1.2e-73 yneP S Thioesterase-like superfamily
EFDNPGAD_00031 3.9e-35 tlp S Belongs to the Tlp family
EFDNPGAD_00032 3.1e-08 sspN S Small acid-soluble spore protein N family
EFDNPGAD_00034 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EFDNPGAD_00035 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EFDNPGAD_00036 2.2e-14 sspO S Belongs to the SspO family
EFDNPGAD_00037 3.9e-19 sspP S Belongs to the SspP family
EFDNPGAD_00038 4.1e-65 hspX O Spore coat protein
EFDNPGAD_00039 4.2e-74 yneK S Protein of unknown function (DUF2621)
EFDNPGAD_00040 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
EFDNPGAD_00041 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
EFDNPGAD_00042 7.1e-127 ccdA O cytochrome c biogenesis protein
EFDNPGAD_00043 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
EFDNPGAD_00044 1.8e-28 yneF S UPF0154 protein
EFDNPGAD_00045 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
EFDNPGAD_00046 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EFDNPGAD_00047 1.3e-32 ynzC S UPF0291 protein
EFDNPGAD_00048 9.2e-113 yneB L resolvase
EFDNPGAD_00049 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
EFDNPGAD_00050 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EFDNPGAD_00052 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
EFDNPGAD_00053 5.8e-74 yndM S Protein of unknown function (DUF2512)
EFDNPGAD_00054 8.6e-139 yndL S Replication protein
EFDNPGAD_00056 0.0 yndJ S YndJ-like protein
EFDNPGAD_00057 2.6e-117 yndH S Domain of unknown function (DUF4166)
EFDNPGAD_00058 7.7e-154 yndG S DoxX-like family
EFDNPGAD_00059 4.2e-220 gerLC S Spore germination protein
EFDNPGAD_00060 4.5e-197 gerAB U Spore germination
EFDNPGAD_00061 5.7e-286 gerAA EG Spore germination protein
EFDNPGAD_00064 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
EFDNPGAD_00065 1.8e-71
EFDNPGAD_00066 7.9e-25 tatA U protein secretion
EFDNPGAD_00069 1.3e-134 S Domain of unknown function, YrpD
EFDNPGAD_00071 1.2e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EFDNPGAD_00073 5.2e-15
EFDNPGAD_00074 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
EFDNPGAD_00075 6.3e-84 yncE S Protein of unknown function (DUF2691)
EFDNPGAD_00076 7.7e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EFDNPGAD_00077 3.5e-247 iolT EGP Major facilitator Superfamily
EFDNPGAD_00078 1.4e-113 yokF 3.1.31.1 L RNA catabolic process
EFDNPGAD_00079 6e-293 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
EFDNPGAD_00080 4e-264 xylA 5.3.1.5 G Belongs to the xylose isomerase family
EFDNPGAD_00081 1e-215 xylR GK ROK family
EFDNPGAD_00082 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
EFDNPGAD_00083 2.7e-255 xynT G MFS/sugar transport protein
EFDNPGAD_00084 1.1e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
EFDNPGAD_00087 6.4e-60 ynaF
EFDNPGAD_00088 1.9e-123 ynaE S Domain of unknown function (DUF3885)
EFDNPGAD_00089 2e-99 ynaD J Acetyltransferase (GNAT) domain
EFDNPGAD_00090 4.9e-145 ynaC
EFDNPGAD_00091 6.8e-80 G regulation of fungal-type cell wall biogenesis
EFDNPGAD_00092 5.8e-39
EFDNPGAD_00093 2.5e-32
EFDNPGAD_00094 5e-10
EFDNPGAD_00098 3.1e-108 S aspartate phosphatase
EFDNPGAD_00099 1.5e-160 M nucleic acid phosphodiester bond hydrolysis
EFDNPGAD_00100 2.4e-24 S SMI1-KNR4 cell-wall
EFDNPGAD_00101 1.2e-124 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
EFDNPGAD_00102 2.1e-57 S Bacteriophage holin family
EFDNPGAD_00103 1.3e-95 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
EFDNPGAD_00105 1e-12
EFDNPGAD_00106 1.8e-87
EFDNPGAD_00107 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
EFDNPGAD_00108 1.8e-221 NU Prophage endopeptidase tail
EFDNPGAD_00109 1e-111 S Phage tail protein
EFDNPGAD_00110 0.0 D phage tail tape measure protein
EFDNPGAD_00113 4e-78 N Phage major tail protein phi13
EFDNPGAD_00115 6.7e-50 S Bacteriophage HK97-gp10, putative tail-component
EFDNPGAD_00116 6.1e-38 S Phage head-tail joining protein
EFDNPGAD_00117 1.3e-37 S Phage gp6-like head-tail connector protein
EFDNPGAD_00118 1.4e-21
EFDNPGAD_00119 1.6e-156 gp36 S capsid protein
EFDNPGAD_00120 3.4e-80 S peptidase activity
EFDNPGAD_00121 2.8e-174 S Phage portal protein
EFDNPGAD_00122 6e-305 S Terminase
EFDNPGAD_00123 8.9e-79 L phage terminase small subunit
EFDNPGAD_00126 8.2e-110
EFDNPGAD_00129 1.5e-59
EFDNPGAD_00131 4.7e-80
EFDNPGAD_00132 6e-94 S nuclease activity
EFDNPGAD_00133 2.4e-64
EFDNPGAD_00134 0.0 S hydrolase activity
EFDNPGAD_00135 2.4e-72 S Protein of unknown function (DUF669)
EFDNPGAD_00137 3.2e-159 tadZ D AAA domain
EFDNPGAD_00138 4.4e-92 S DNA protection
EFDNPGAD_00140 5e-20 S Uncharacterized protein YqaH
EFDNPGAD_00143 6.2e-23
EFDNPGAD_00144 3.2e-17
EFDNPGAD_00145 5.5e-29 K TRANSCRIPTIONal
EFDNPGAD_00146 3.3e-45 E Zn peptidase
EFDNPGAD_00147 1.4e-132 L Belongs to the 'phage' integrase family
EFDNPGAD_00148 7e-261 glnA 6.3.1.2 E glutamine synthetase
EFDNPGAD_00149 1.1e-68 glnR K transcriptional
EFDNPGAD_00150 3.3e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
EFDNPGAD_00151 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EFDNPGAD_00152 1.7e-176 spoVK O stage V sporulation protein K
EFDNPGAD_00153 8e-116 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EFDNPGAD_00154 2e-109 ymaB
EFDNPGAD_00155 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EFDNPGAD_00156 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EFDNPGAD_00157 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
EFDNPGAD_00158 4.5e-22 ymzA
EFDNPGAD_00159 6.3e-23
EFDNPGAD_00160 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
EFDNPGAD_00161 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EFDNPGAD_00162 2.1e-46 ymaF S YmaF family
EFDNPGAD_00164 4.9e-51 ebrA P Small Multidrug Resistance protein
EFDNPGAD_00165 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
EFDNPGAD_00166 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
EFDNPGAD_00167 2.1e-126 ymaC S Replication protein
EFDNPGAD_00168 4.6e-252 aprX O Belongs to the peptidase S8 family
EFDNPGAD_00169 6.6e-164 ymaE S Metallo-beta-lactamase superfamily
EFDNPGAD_00170 1.2e-61 ymzB
EFDNPGAD_00171 2.5e-233 cypA C Cytochrome P450
EFDNPGAD_00172 0.0 pks13 HQ Beta-ketoacyl synthase
EFDNPGAD_00173 0.0 dhbF IQ polyketide synthase
EFDNPGAD_00174 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
EFDNPGAD_00175 0.0 pfaA Q Polyketide synthase of type I
EFDNPGAD_00176 0.0 rhiB IQ polyketide synthase
EFDNPGAD_00177 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
EFDNPGAD_00178 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
EFDNPGAD_00179 1.3e-245 pksG 2.3.3.10 I synthase
EFDNPGAD_00180 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EFDNPGAD_00181 1.4e-37 acpK IQ Phosphopantetheine attachment site
EFDNPGAD_00182 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EFDNPGAD_00183 2.4e-186 pksD Q Acyl transferase domain
EFDNPGAD_00185 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EFDNPGAD_00186 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
EFDNPGAD_00187 4.4e-109 pksA K Transcriptional regulator
EFDNPGAD_00188 1.2e-97 ymcC S Membrane
EFDNPGAD_00190 2.3e-70 S Regulatory protein YrvL
EFDNPGAD_00191 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EFDNPGAD_00192 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EFDNPGAD_00193 2.2e-88 cotE S Spore coat protein
EFDNPGAD_00194 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
EFDNPGAD_00195 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EFDNPGAD_00196 6.5e-218 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EFDNPGAD_00197 2.7e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
EFDNPGAD_00198 1.2e-36 spoVS S Stage V sporulation protein S
EFDNPGAD_00199 1.9e-152 ymdB S protein conserved in bacteria
EFDNPGAD_00200 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
EFDNPGAD_00201 1e-215 pbpX V Beta-lactamase
EFDNPGAD_00202 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EFDNPGAD_00203 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
EFDNPGAD_00204 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EFDNPGAD_00205 1.9e-124 ymfM S protein conserved in bacteria
EFDNPGAD_00206 2.7e-143 ymfK S Protein of unknown function (DUF3388)
EFDNPGAD_00207 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
EFDNPGAD_00208 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
EFDNPGAD_00209 1.4e-242 ymfH S zinc protease
EFDNPGAD_00210 2.9e-235 ymfF S Peptidase M16
EFDNPGAD_00211 1.5e-206 ymfD EGP Major facilitator Superfamily
EFDNPGAD_00212 1.4e-133 ymfC K Transcriptional regulator
EFDNPGAD_00213 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
EFDNPGAD_00214 4.4e-32 S YlzJ-like protein
EFDNPGAD_00215 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
EFDNPGAD_00216 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EFDNPGAD_00217 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EFDNPGAD_00218 5.9e-222 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
EFDNPGAD_00219 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EFDNPGAD_00220 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
EFDNPGAD_00221 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
EFDNPGAD_00222 2.6e-42 ymxH S YlmC YmxH family
EFDNPGAD_00223 4.4e-233 pepR S Belongs to the peptidase M16 family
EFDNPGAD_00224 4.2e-183 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
EFDNPGAD_00225 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
EFDNPGAD_00226 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EFDNPGAD_00227 6.1e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
EFDNPGAD_00228 1.3e-173 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EFDNPGAD_00229 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EFDNPGAD_00230 3e-44 ylxP S protein conserved in bacteria
EFDNPGAD_00231 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EFDNPGAD_00232 3.1e-47 ylxQ J ribosomal protein
EFDNPGAD_00233 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
EFDNPGAD_00234 1.1e-203 nusA K Participates in both transcription termination and antitermination
EFDNPGAD_00235 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
EFDNPGAD_00236 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EFDNPGAD_00237 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EFDNPGAD_00238 7.7e-233 rasP M zinc metalloprotease
EFDNPGAD_00239 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
EFDNPGAD_00240 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
EFDNPGAD_00241 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EFDNPGAD_00242 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EFDNPGAD_00243 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
EFDNPGAD_00244 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EFDNPGAD_00245 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
EFDNPGAD_00246 4.3e-78 ylxL
EFDNPGAD_00247 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EFDNPGAD_00248 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
EFDNPGAD_00249 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
EFDNPGAD_00250 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
EFDNPGAD_00251 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
EFDNPGAD_00252 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
EFDNPGAD_00253 4.8e-157 flhG D Belongs to the ParA family
EFDNPGAD_00254 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
EFDNPGAD_00255 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EFDNPGAD_00256 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EFDNPGAD_00257 3.6e-132 fliR N Flagellar biosynthetic protein FliR
EFDNPGAD_00258 2.2e-36 fliQ N Role in flagellar biosynthesis
EFDNPGAD_00259 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
EFDNPGAD_00260 9.3e-97 fliZ N Flagellar biosynthesis protein, FliO
EFDNPGAD_00261 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
EFDNPGAD_00262 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EFDNPGAD_00263 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EFDNPGAD_00264 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
EFDNPGAD_00265 8.2e-140 flgG N Flagellar basal body rod
EFDNPGAD_00266 1.7e-72 flgD N Flagellar basal body rod modification protein
EFDNPGAD_00267 1.2e-221 fliK N Flagellar hook-length control protein
EFDNPGAD_00268 7.7e-37 ylxF S MgtE intracellular N domain
EFDNPGAD_00269 1.5e-69 fliJ N Flagellar biosynthesis chaperone
EFDNPGAD_00270 2.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
EFDNPGAD_00271 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
EFDNPGAD_00272 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EFDNPGAD_00273 2.4e-255 fliF N The M ring may be actively involved in energy transduction
EFDNPGAD_00274 1.9e-31 fliE N Flagellar hook-basal body
EFDNPGAD_00275 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
EFDNPGAD_00276 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
EFDNPGAD_00277 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EFDNPGAD_00278 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EFDNPGAD_00279 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EFDNPGAD_00280 2.5e-169 xerC L tyrosine recombinase XerC
EFDNPGAD_00281 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EFDNPGAD_00282 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EFDNPGAD_00283 1.7e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
EFDNPGAD_00284 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EFDNPGAD_00285 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
EFDNPGAD_00286 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
EFDNPGAD_00287 8.5e-291 ylqG
EFDNPGAD_00288 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EFDNPGAD_00289 4.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EFDNPGAD_00290 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EFDNPGAD_00291 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
EFDNPGAD_00292 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EFDNPGAD_00293 1.3e-61 ylqD S YlqD protein
EFDNPGAD_00294 1.2e-36 ylqC S Belongs to the UPF0109 family
EFDNPGAD_00295 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
EFDNPGAD_00296 6e-236 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EFDNPGAD_00297 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EFDNPGAD_00298 2.9e-87
EFDNPGAD_00299 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EFDNPGAD_00300 0.0 smc D Required for chromosome condensation and partitioning
EFDNPGAD_00301 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EFDNPGAD_00302 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EFDNPGAD_00303 6.1e-129 IQ reductase
EFDNPGAD_00304 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EFDNPGAD_00305 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EFDNPGAD_00306 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
EFDNPGAD_00307 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EFDNPGAD_00308 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
EFDNPGAD_00309 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
EFDNPGAD_00310 2.7e-302 yloV S kinase related to dihydroxyacetone kinase
EFDNPGAD_00311 5.5e-59 asp S protein conserved in bacteria
EFDNPGAD_00312 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
EFDNPGAD_00313 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
EFDNPGAD_00314 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
EFDNPGAD_00315 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EFDNPGAD_00316 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
EFDNPGAD_00317 2.4e-141 stp 3.1.3.16 T phosphatase
EFDNPGAD_00318 4.8e-207 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EFDNPGAD_00319 2.9e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EFDNPGAD_00320 3.8e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EFDNPGAD_00321 6e-85 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EFDNPGAD_00322 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EFDNPGAD_00323 8.8e-226 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EFDNPGAD_00324 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EFDNPGAD_00325 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
EFDNPGAD_00326 1.5e-40 ylzA S Belongs to the UPF0296 family
EFDNPGAD_00327 2.4e-156 yloC S stress-induced protein
EFDNPGAD_00328 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
EFDNPGAD_00329 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
EFDNPGAD_00330 4.3e-83 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
EFDNPGAD_00331 2e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
EFDNPGAD_00332 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
EFDNPGAD_00333 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
EFDNPGAD_00334 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
EFDNPGAD_00335 1.1e-179 cysP P phosphate transporter
EFDNPGAD_00336 3.5e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
EFDNPGAD_00338 2.9e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EFDNPGAD_00339 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EFDNPGAD_00340 2.9e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EFDNPGAD_00341 4.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
EFDNPGAD_00342 0.0 carB 6.3.5.5 F Belongs to the CarB family
EFDNPGAD_00343 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
EFDNPGAD_00344 1.7e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EFDNPGAD_00345 1.4e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
EFDNPGAD_00346 9e-232 pyrP F Xanthine uracil
EFDNPGAD_00347 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EFDNPGAD_00348 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EFDNPGAD_00349 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EFDNPGAD_00350 1.3e-63 dksA T COG1734 DnaK suppressor protein
EFDNPGAD_00351 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EFDNPGAD_00352 2.6e-67 divIVA D Cell division initiation protein
EFDNPGAD_00353 6.7e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
EFDNPGAD_00354 1.3e-39 yggT S membrane
EFDNPGAD_00355 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EFDNPGAD_00356 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EFDNPGAD_00357 1.1e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
EFDNPGAD_00358 2.4e-37 ylmC S sporulation protein
EFDNPGAD_00359 1.3e-256 argE 3.5.1.16 E Acetylornithine deacetylase
EFDNPGAD_00360 1.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
EFDNPGAD_00361 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EFDNPGAD_00362 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EFDNPGAD_00363 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
EFDNPGAD_00364 0.0 bpr O COG1404 Subtilisin-like serine proteases
EFDNPGAD_00365 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EFDNPGAD_00366 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EFDNPGAD_00367 6.2e-58 sbp S small basic protein
EFDNPGAD_00368 1e-102 ylxX S protein conserved in bacteria
EFDNPGAD_00369 2.4e-103 ylxW S protein conserved in bacteria
EFDNPGAD_00370 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EFDNPGAD_00371 5.3e-167 murB 1.3.1.98 M cell wall formation
EFDNPGAD_00372 2.3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EFDNPGAD_00373 5.7e-186 spoVE D Belongs to the SEDS family
EFDNPGAD_00374 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EFDNPGAD_00375 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EFDNPGAD_00376 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EFDNPGAD_00377 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
EFDNPGAD_00378 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
EFDNPGAD_00379 3.7e-44 ftsL D Essential cell division protein
EFDNPGAD_00380 6.6e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EFDNPGAD_00381 2.9e-78 mraZ K Belongs to the MraZ family
EFDNPGAD_00382 2.9e-309 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EFDNPGAD_00383 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EFDNPGAD_00384 4e-89 ylbP K n-acetyltransferase
EFDNPGAD_00385 6.8e-75 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
EFDNPGAD_00386 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
EFDNPGAD_00387 1.3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
EFDNPGAD_00389 2.8e-235 ylbM S Belongs to the UPF0348 family
EFDNPGAD_00390 3.4e-186 ylbL T Belongs to the peptidase S16 family
EFDNPGAD_00391 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
EFDNPGAD_00392 3.8e-221 ylbJ S Sporulation integral membrane protein YlbJ
EFDNPGAD_00393 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EFDNPGAD_00394 1.9e-98 rsmD 2.1.1.171 L Methyltransferase
EFDNPGAD_00395 7.5e-39 ylbG S UPF0298 protein
EFDNPGAD_00396 1.8e-75 ylbF S Belongs to the UPF0342 family
EFDNPGAD_00397 6.7e-37 ylbE S YlbE-like protein
EFDNPGAD_00398 4.1e-63 ylbD S Putative coat protein
EFDNPGAD_00399 3e-201 ylbC S protein with SCP PR1 domains
EFDNPGAD_00400 9.8e-74 ylbB T COG0517 FOG CBS domain
EFDNPGAD_00401 7e-62 ylbA S YugN-like family
EFDNPGAD_00402 3e-167 ctaG S cytochrome c oxidase
EFDNPGAD_00403 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
EFDNPGAD_00404 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
EFDNPGAD_00405 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EFDNPGAD_00406 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
EFDNPGAD_00407 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EFDNPGAD_00408 2.6e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
EFDNPGAD_00409 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EFDNPGAD_00410 4.5e-214 ftsW D Belongs to the SEDS family
EFDNPGAD_00411 8.7e-44 ylaN S Belongs to the UPF0358 family
EFDNPGAD_00412 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
EFDNPGAD_00413 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EFDNPGAD_00414 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
EFDNPGAD_00415 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EFDNPGAD_00416 2.5e-32 ylaI S protein conserved in bacteria
EFDNPGAD_00417 4.2e-47 ylaH S YlaH-like protein
EFDNPGAD_00418 0.0 typA T GTP-binding protein TypA
EFDNPGAD_00419 8.2e-22 S Family of unknown function (DUF5325)
EFDNPGAD_00420 1.8e-38 ylaE
EFDNPGAD_00421 1.2e-11 sigC S Putative zinc-finger
EFDNPGAD_00422 2.7e-91 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
EFDNPGAD_00423 2.7e-42 ylaB
EFDNPGAD_00424 0.0 ylaA
EFDNPGAD_00425 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
EFDNPGAD_00426 6.5e-173 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EFDNPGAD_00427 6.9e-78 ykzC S Acetyltransferase (GNAT) family
EFDNPGAD_00428 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
EFDNPGAD_00429 7.1e-26 ykzI
EFDNPGAD_00430 7.1e-118 yktB S Belongs to the UPF0637 family
EFDNPGAD_00431 1.6e-42 yktA S Belongs to the UPF0223 family
EFDNPGAD_00432 3.5e-277 speA 4.1.1.19 E Arginine
EFDNPGAD_00433 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
EFDNPGAD_00434 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EFDNPGAD_00435 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EFDNPGAD_00436 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EFDNPGAD_00437 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EFDNPGAD_00438 2e-115 recN L Putative cell-wall binding lipoprotein
EFDNPGAD_00440 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EFDNPGAD_00441 1.4e-147 ykrA S hydrolases of the HAD superfamily
EFDNPGAD_00442 8.2e-31 ykzG S Belongs to the UPF0356 family
EFDNPGAD_00443 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EFDNPGAD_00444 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EFDNPGAD_00445 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
EFDNPGAD_00446 1.6e-162 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
EFDNPGAD_00447 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
EFDNPGAD_00448 1.5e-43 abrB K of stationary sporulation gene expression
EFDNPGAD_00449 7.7e-183 mreB D Rod-share determining protein MreBH
EFDNPGAD_00450 1.1e-12 S Uncharacterized protein YkpC
EFDNPGAD_00451 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
EFDNPGAD_00452 1.5e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EFDNPGAD_00453 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EFDNPGAD_00454 8.1e-39 ykoA
EFDNPGAD_00455 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
EFDNPGAD_00456 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
EFDNPGAD_00457 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
EFDNPGAD_00458 3.1e-136 fruR K Transcriptional regulator
EFDNPGAD_00459 2.1e-211 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
EFDNPGAD_00460 2.5e-124 macB V ABC transporter, ATP-binding protein
EFDNPGAD_00461 3e-159 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EFDNPGAD_00462 1e-117 yknW S Yip1 domain
EFDNPGAD_00463 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
EFDNPGAD_00464 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
EFDNPGAD_00465 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EFDNPGAD_00466 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
EFDNPGAD_00467 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
EFDNPGAD_00468 8.1e-246 moeA 2.10.1.1 H molybdopterin
EFDNPGAD_00469 5.3e-192 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EFDNPGAD_00470 3.9e-110 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
EFDNPGAD_00471 2.9e-147 yknT
EFDNPGAD_00472 5.8e-95 rok K Repressor of ComK
EFDNPGAD_00473 4.4e-82 ykuV CO thiol-disulfide
EFDNPGAD_00474 3.9e-101 ykuU O Alkyl hydroperoxide reductase
EFDNPGAD_00475 8.8e-142 ykuT M Mechanosensitive ion channel
EFDNPGAD_00476 9e-37 ykuS S Belongs to the UPF0180 family
EFDNPGAD_00477 5.8e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EFDNPGAD_00478 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EFDNPGAD_00479 3.2e-80 fld C Flavodoxin
EFDNPGAD_00480 3.2e-177 ykuO
EFDNPGAD_00481 5.7e-88 fld C Flavodoxin domain
EFDNPGAD_00482 3.5e-168 ccpC K Transcriptional regulator
EFDNPGAD_00483 1.6e-76 ykuL S CBS domain
EFDNPGAD_00484 3.9e-27 ykzF S Antirepressor AbbA
EFDNPGAD_00485 4.4e-94 ykuK S Ribonuclease H-like
EFDNPGAD_00486 3.9e-37 ykuJ S protein conserved in bacteria
EFDNPGAD_00487 5.2e-234 ykuI T Diguanylate phosphodiesterase
EFDNPGAD_00489 1.7e-93 M Peptidoglycan-binding domain 1 protein
EFDNPGAD_00490 0.0 3.2.1.132 M Putative peptidoglycan binding domain
EFDNPGAD_00491 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EFDNPGAD_00492 9.4e-166 ykuE S Metallophosphoesterase
EFDNPGAD_00493 4.6e-88 ykuD S protein conserved in bacteria
EFDNPGAD_00494 1.6e-238 ykuC EGP Major facilitator Superfamily
EFDNPGAD_00495 1.7e-84 ykyB S YkyB-like protein
EFDNPGAD_00496 1.6e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
EFDNPGAD_00497 2.2e-15
EFDNPGAD_00498 8e-224 patA 2.6.1.1 E Aminotransferase
EFDNPGAD_00499 0.0 pilS 2.7.13.3 T Histidine kinase
EFDNPGAD_00500 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
EFDNPGAD_00501 8e-124 ykwD J protein with SCP PR1 domains
EFDNPGAD_00502 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
EFDNPGAD_00503 2e-264 mcpC NT chemotaxis protein
EFDNPGAD_00504 1.2e-131 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EFDNPGAD_00505 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
EFDNPGAD_00506 7.2e-39 splA S Transcriptional regulator
EFDNPGAD_00507 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EFDNPGAD_00508 2.1e-39 ptsH G phosphocarrier protein HPr
EFDNPGAD_00509 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EFDNPGAD_00510 4.5e-128 glcT K antiterminator
EFDNPGAD_00512 9.8e-180 ykvZ 5.1.1.1 K Transcriptional regulator
EFDNPGAD_00514 8.7e-209 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
EFDNPGAD_00515 3.8e-09
EFDNPGAD_00516 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
EFDNPGAD_00517 4.9e-90 stoA CO thiol-disulfide
EFDNPGAD_00518 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EFDNPGAD_00519 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
EFDNPGAD_00520 2.8e-28
EFDNPGAD_00521 6e-25 ykvS S protein conserved in bacteria
EFDNPGAD_00522 5.6e-46 ykvR S Protein of unknown function (DUF3219)
EFDNPGAD_00523 8.5e-133 G Glycosyl hydrolases family 18
EFDNPGAD_00524 1.2e-35 3.5.1.104 M LysM domain
EFDNPGAD_00525 4e-217 ykvP 3.5.1.28 M Glycosyl transferases group 1
EFDNPGAD_00526 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
EFDNPGAD_00527 2e-61 ykvN K Transcriptional regulator
EFDNPGAD_00528 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EFDNPGAD_00529 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
EFDNPGAD_00530 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
EFDNPGAD_00531 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EFDNPGAD_00532 8.7e-182 ykvI S membrane
EFDNPGAD_00533 0.0 clpE O Belongs to the ClpA ClpB family
EFDNPGAD_00534 2.7e-138 motA N flagellar motor
EFDNPGAD_00535 2.5e-125 motB N Flagellar motor protein
EFDNPGAD_00536 1.3e-75 ykvE K transcriptional
EFDNPGAD_00537 2.5e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
EFDNPGAD_00538 1.4e-64 eag
EFDNPGAD_00539 6.4e-09 S Spo0E like sporulation regulatory protein
EFDNPGAD_00540 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
EFDNPGAD_00541 1.3e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EFDNPGAD_00542 7.2e-115 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
EFDNPGAD_00543 7.5e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EFDNPGAD_00544 4.1e-231 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
EFDNPGAD_00545 8e-232 mtnE 2.6.1.83 E Aminotransferase
EFDNPGAD_00546 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EFDNPGAD_00547 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EFDNPGAD_00548 3.3e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EFDNPGAD_00550 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EFDNPGAD_00551 0.0 kinE 2.7.13.3 T Histidine kinase
EFDNPGAD_00552 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
EFDNPGAD_00553 4.5e-22 ykzE
EFDNPGAD_00554 1.2e-10 ydfR S Protein of unknown function (DUF421)
EFDNPGAD_00555 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
EFDNPGAD_00556 7e-156 htpX O Belongs to the peptidase M48B family
EFDNPGAD_00557 1.5e-124 ykrK S Domain of unknown function (DUF1836)
EFDNPGAD_00558 1.9e-26 sspD S small acid-soluble spore protein
EFDNPGAD_00559 8.2e-117 rsgI S Anti-sigma factor N-terminus
EFDNPGAD_00560 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EFDNPGAD_00561 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
EFDNPGAD_00562 1.4e-116 ykoX S membrane-associated protein
EFDNPGAD_00563 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
EFDNPGAD_00564 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EFDNPGAD_00565 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
EFDNPGAD_00566 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EFDNPGAD_00567 0.0 ykoS
EFDNPGAD_00568 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
EFDNPGAD_00569 3.7e-99 ykoP G polysaccharide deacetylase
EFDNPGAD_00570 2.3e-220 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
EFDNPGAD_00571 1.3e-81 mhqR K transcriptional
EFDNPGAD_00572 6.9e-26 ykoL
EFDNPGAD_00573 5.9e-18
EFDNPGAD_00574 1.4e-53 tnrA K transcriptional
EFDNPGAD_00575 2.2e-222 mgtE P Acts as a magnesium transporter
EFDNPGAD_00578 4.4e-86 ykoJ S Peptidase propeptide and YPEB domain
EFDNPGAD_00579 1.1e-113 ykoI S Peptidase propeptide and YPEB domain
EFDNPGAD_00580 9.4e-245 ykoH 2.7.13.3 T Histidine kinase
EFDNPGAD_00581 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFDNPGAD_00582 7.9e-111 ykoF S YKOF-related Family
EFDNPGAD_00583 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
EFDNPGAD_00584 4.6e-311 P ABC transporter, ATP-binding protein
EFDNPGAD_00585 1.8e-136 ykoC P Cobalt transport protein
EFDNPGAD_00586 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EFDNPGAD_00587 1.7e-176 isp O Belongs to the peptidase S8 family
EFDNPGAD_00588 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EFDNPGAD_00589 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
EFDNPGAD_00591 8.4e-72 ohrB O Organic hydroperoxide resistance protein
EFDNPGAD_00592 3.9e-75 ohrR K COG1846 Transcriptional regulators
EFDNPGAD_00593 1.3e-70 ohrA O Organic hydroperoxide resistance protein
EFDNPGAD_00594 2.5e-228 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EFDNPGAD_00595 1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EFDNPGAD_00596 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
EFDNPGAD_00597 1.1e-50 ykkD P Multidrug resistance protein
EFDNPGAD_00598 3.5e-55 ykkC P Multidrug resistance protein
EFDNPGAD_00599 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EFDNPGAD_00600 1e-98 ykkA S Protein of unknown function (DUF664)
EFDNPGAD_00601 5.4e-130 ykjA S Protein of unknown function (DUF421)
EFDNPGAD_00602 1e-07
EFDNPGAD_00603 1e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EFDNPGAD_00604 1.5e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
EFDNPGAD_00605 5.3e-161 ykgA E Amidinotransferase
EFDNPGAD_00606 7.4e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
EFDNPGAD_00607 7.7e-188 ykfD E Belongs to the ABC transporter superfamily
EFDNPGAD_00608 5.3e-172 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EFDNPGAD_00609 3.2e-203 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
EFDNPGAD_00610 8.1e-179 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
EFDNPGAD_00612 0.0 dppE E ABC transporter substrate-binding protein
EFDNPGAD_00613 3.4e-191 dppD P Belongs to the ABC transporter superfamily
EFDNPGAD_00614 3.9e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EFDNPGAD_00615 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EFDNPGAD_00616 7.9e-154 dppA E D-aminopeptidase
EFDNPGAD_00617 1e-137 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
EFDNPGAD_00618 8.5e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EFDNPGAD_00620 1.3e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EFDNPGAD_00621 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EFDNPGAD_00623 7.2e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
EFDNPGAD_00624 9.4e-242 steT E amino acid
EFDNPGAD_00625 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
EFDNPGAD_00626 5.8e-175 pit P phosphate transporter
EFDNPGAD_00627 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
EFDNPGAD_00628 6.7e-23 spoIISB S Stage II sporulation protein SB
EFDNPGAD_00629 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EFDNPGAD_00630 9.3e-40 xhlB S SPP1 phage holin
EFDNPGAD_00631 2.8e-39 xhlA S Haemolysin XhlA
EFDNPGAD_00632 1.2e-154 xepA
EFDNPGAD_00633 1.7e-23 xkdX
EFDNPGAD_00634 2.6e-55 xkdW S XkdW protein
EFDNPGAD_00635 0.0
EFDNPGAD_00636 6.7e-41
EFDNPGAD_00637 4e-104 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
EFDNPGAD_00638 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
EFDNPGAD_00639 9.6e-71 xkdS S Protein of unknown function (DUF2634)
EFDNPGAD_00640 2.1e-39 xkdR S Protein of unknown function (DUF2577)
EFDNPGAD_00641 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
EFDNPGAD_00642 3.7e-122 xkdP S Lysin motif
EFDNPGAD_00643 0.0 xkdO L Transglycosylase SLT domain
EFDNPGAD_00644 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
EFDNPGAD_00645 6.1e-76 xkdM S Phage tail tube protein
EFDNPGAD_00646 2.5e-256 xkdK S Phage tail sheath C-terminal domain
EFDNPGAD_00647 1.9e-77 xkdJ
EFDNPGAD_00648 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
EFDNPGAD_00649 8.7e-65 yqbH S Domain of unknown function (DUF3599)
EFDNPGAD_00650 5.5e-65 yqbG S Protein of unknown function (DUF3199)
EFDNPGAD_00651 5.8e-169 xkdG S Phage capsid family
EFDNPGAD_00652 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
EFDNPGAD_00653 5.4e-286 yqbA S portal protein
EFDNPGAD_00654 9.6e-255 xtmB S phage terminase, large subunit
EFDNPGAD_00655 4.8e-140 xtmA L phage terminase small subunit
EFDNPGAD_00656 4.4e-86 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
EFDNPGAD_00657 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
EFDNPGAD_00660 6.4e-119 xkdC L Bacterial dnaA protein
EFDNPGAD_00661 5.9e-157 xkdB K sequence-specific DNA binding
EFDNPGAD_00663 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
EFDNPGAD_00664 1.6e-111 xkdA E IrrE N-terminal-like domain
EFDNPGAD_00665 4.4e-160 ydbD P Catalase
EFDNPGAD_00666 4.2e-112 yjqB S Pfam:DUF867
EFDNPGAD_00667 2.1e-61 yjqA S Bacterial PH domain
EFDNPGAD_00668 9.1e-170 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
EFDNPGAD_00669 6.3e-41 S YCII-related domain
EFDNPGAD_00671 2.1e-213 S response regulator aspartate phosphatase
EFDNPGAD_00672 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
EFDNPGAD_00673 3.3e-80 yjoA S DinB family
EFDNPGAD_00674 4.3e-130 MA20_18170 S membrane transporter protein
EFDNPGAD_00675 2e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
EFDNPGAD_00676 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
EFDNPGAD_00677 2.3e-184 exuR K transcriptional
EFDNPGAD_00678 3.7e-227 exuT G Sugar (and other) transporter
EFDNPGAD_00679 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EFDNPGAD_00680 4.7e-215 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
EFDNPGAD_00681 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
EFDNPGAD_00682 3e-195 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
EFDNPGAD_00683 5.8e-250 yjmB G symporter YjmB
EFDNPGAD_00684 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
EFDNPGAD_00685 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
EFDNPGAD_00686 7.1e-66 yjlC S Protein of unknown function (DUF1641)
EFDNPGAD_00687 2.8e-93 yjlB S Cupin domain
EFDNPGAD_00688 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
EFDNPGAD_00689 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
EFDNPGAD_00690 1.9e-122 ybbM S transport system, permease component
EFDNPGAD_00691 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
EFDNPGAD_00692 8.2e-30
EFDNPGAD_00693 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EFDNPGAD_00694 3.8e-226 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
EFDNPGAD_00696 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
EFDNPGAD_00697 8.7e-07 S Domain of unknown function (DUF4352)
EFDNPGAD_00698 4.3e-95 yjgD S Protein of unknown function (DUF1641)
EFDNPGAD_00699 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
EFDNPGAD_00700 8.9e-104 yjgB S Domain of unknown function (DUF4309)
EFDNPGAD_00701 1.2e-45 T PhoQ Sensor
EFDNPGAD_00702 1.6e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
EFDNPGAD_00703 3.6e-21 yjfB S Putative motility protein
EFDNPGAD_00704 5.5e-83 S Protein of unknown function (DUF2690)
EFDNPGAD_00705 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
EFDNPGAD_00707 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EFDNPGAD_00708 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
EFDNPGAD_00709 4.2e-29 S Domain of unknown function (DUF4177)
EFDNPGAD_00710 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EFDNPGAD_00712 2.5e-94 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
EFDNPGAD_00713 4.8e-51 yjdF S Protein of unknown function (DUF2992)
EFDNPGAD_00714 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
EFDNPGAD_00715 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
EFDNPGAD_00716 5.6e-65 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
EFDNPGAD_00717 1.3e-264 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
EFDNPGAD_00719 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
EFDNPGAD_00720 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
EFDNPGAD_00721 1.1e-92 yqaS L DNA packaging
EFDNPGAD_00722 4.1e-49 S YjcQ protein
EFDNPGAD_00723 1.6e-72 yjcP
EFDNPGAD_00724 8.5e-81 L Transposase
EFDNPGAD_00727 2.6e-44 yjcN
EFDNPGAD_00728 2.1e-190 S Putative amidase domain
EFDNPGAD_00731 1.1e-212 yjcL S Protein of unknown function (DUF819)
EFDNPGAD_00732 3.7e-99 rimJ 2.3.1.128 J Alanine acetyltransferase
EFDNPGAD_00733 2.9e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EFDNPGAD_00734 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EFDNPGAD_00735 1.8e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
EFDNPGAD_00736 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
EFDNPGAD_00737 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EFDNPGAD_00738 1.7e-38
EFDNPGAD_00739 0.0 yjcD 3.6.4.12 L DNA helicase
EFDNPGAD_00740 2.9e-38 spoVIF S Stage VI sporulation protein F
EFDNPGAD_00743 8.7e-57 yjcA S Protein of unknown function (DUF1360)
EFDNPGAD_00744 2.3e-55 cotV S Spore Coat Protein X and V domain
EFDNPGAD_00745 3e-32 cotW
EFDNPGAD_00746 6.4e-77 cotX S Spore Coat Protein X and V domain
EFDNPGAD_00747 3.4e-96 cotY S Spore coat protein Z
EFDNPGAD_00748 5.2e-83 cotZ S Spore coat protein
EFDNPGAD_00749 5.9e-54 yjbX S Spore coat protein
EFDNPGAD_00750 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
EFDNPGAD_00751 5.3e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
EFDNPGAD_00752 6e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EFDNPGAD_00753 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
EFDNPGAD_00754 3e-30 thiS H thiamine diphosphate biosynthetic process
EFDNPGAD_00755 7.2e-219 thiO 1.4.3.19 E Glycine oxidase
EFDNPGAD_00756 3.8e-108 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
EFDNPGAD_00757 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EFDNPGAD_00758 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EFDNPGAD_00759 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
EFDNPGAD_00760 9.5e-161 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EFDNPGAD_00761 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EFDNPGAD_00762 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
EFDNPGAD_00763 7.1e-62 yjbL S Belongs to the UPF0738 family
EFDNPGAD_00764 2.4e-101 yjbK S protein conserved in bacteria
EFDNPGAD_00765 1.5e-87 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EFDNPGAD_00766 3.7e-72 yjbI S Bacterial-like globin
EFDNPGAD_00767 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
EFDNPGAD_00769 1.8e-20
EFDNPGAD_00770 0.0 pepF E oligoendopeptidase F
EFDNPGAD_00771 2.3e-223 yjbF S Competence protein
EFDNPGAD_00772 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EFDNPGAD_00773 6e-112 yjbE P Integral membrane protein TerC family
EFDNPGAD_00774 2.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EFDNPGAD_00775 6.9e-104 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EFDNPGAD_00776 8.6e-196 yjbB EGP Major Facilitator Superfamily
EFDNPGAD_00777 5.5e-172 oppF E Belongs to the ABC transporter superfamily
EFDNPGAD_00778 3e-198 oppD P Belongs to the ABC transporter superfamily
EFDNPGAD_00779 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EFDNPGAD_00780 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EFDNPGAD_00781 0.0 oppA E ABC transporter substrate-binding protein
EFDNPGAD_00782 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
EFDNPGAD_00783 5e-147 yjbA S Belongs to the UPF0736 family
EFDNPGAD_00784 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EFDNPGAD_00785 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EFDNPGAD_00786 1.6e-251 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
EFDNPGAD_00787 6.5e-187 appF E Belongs to the ABC transporter superfamily
EFDNPGAD_00788 1.8e-184 appD P Belongs to the ABC transporter superfamily
EFDNPGAD_00789 7.8e-151 yjaZ O Zn-dependent protease
EFDNPGAD_00790 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EFDNPGAD_00791 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EFDNPGAD_00792 2.7e-22 yjzB
EFDNPGAD_00793 7.3e-26 comZ S ComZ
EFDNPGAD_00794 1.1e-183 med S Transcriptional activator protein med
EFDNPGAD_00795 7.3e-103 yjaV
EFDNPGAD_00796 6.2e-142 yjaU I carboxylic ester hydrolase activity
EFDNPGAD_00797 2.3e-16 yjzD S Protein of unknown function (DUF2929)
EFDNPGAD_00798 9.5e-28 yjzC S YjzC-like protein
EFDNPGAD_00799 3.8e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EFDNPGAD_00800 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
EFDNPGAD_00801 3.9e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
EFDNPGAD_00802 4.4e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
EFDNPGAD_00803 2.2e-137 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
EFDNPGAD_00804 3.1e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EFDNPGAD_00805 5.4e-200 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EFDNPGAD_00806 1.7e-88 norB G Major Facilitator Superfamily
EFDNPGAD_00807 4.3e-272 yitY C D-arabinono-1,4-lactone oxidase
EFDNPGAD_00808 1.5e-22 pilT S Proteolipid membrane potential modulator
EFDNPGAD_00809 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
EFDNPGAD_00810 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
EFDNPGAD_00811 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
EFDNPGAD_00812 1.2e-17 S Protein of unknown function (DUF3813)
EFDNPGAD_00813 1.9e-72 ipi S Intracellular proteinase inhibitor
EFDNPGAD_00814 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
EFDNPGAD_00815 8.4e-159 yitS S protein conserved in bacteria
EFDNPGAD_00816 1.6e-310 nprB 3.4.24.28 E Peptidase M4
EFDNPGAD_00817 1.4e-44 yitR S Domain of unknown function (DUF3784)
EFDNPGAD_00818 2e-95
EFDNPGAD_00819 1.5e-58 K Transcriptional regulator PadR-like family
EFDNPGAD_00820 1.5e-97 S Sporulation delaying protein SdpA
EFDNPGAD_00821 2.8e-171
EFDNPGAD_00822 8.5e-94
EFDNPGAD_00823 4e-161 cvfB S protein conserved in bacteria
EFDNPGAD_00824 8.6e-55 yajQ S Belongs to the UPF0234 family
EFDNPGAD_00825 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
EFDNPGAD_00826 5.8e-82 yjcF S Acetyltransferase (GNAT) domain
EFDNPGAD_00827 1.8e-161 yitH K Acetyltransferase (GNAT) domain
EFDNPGAD_00828 4e-229 yitG EGP Major facilitator Superfamily
EFDNPGAD_00829 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
EFDNPGAD_00830 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
EFDNPGAD_00831 1.9e-141 yitD 4.4.1.19 S synthase
EFDNPGAD_00832 4.9e-125 comB 3.1.3.71 H Belongs to the ComB family
EFDNPGAD_00833 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
EFDNPGAD_00834 3.2e-233 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
EFDNPGAD_00835 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
EFDNPGAD_00836 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EFDNPGAD_00837 4e-36 mcbG S Pentapeptide repeats (9 copies)
EFDNPGAD_00838 1.7e-281 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EFDNPGAD_00839 6.4e-108 argO S Lysine exporter protein LysE YggA
EFDNPGAD_00840 1.3e-93 yisT S DinB family
EFDNPGAD_00841 4.5e-199 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
EFDNPGAD_00842 2.4e-184 purR K helix_turn _helix lactose operon repressor
EFDNPGAD_00843 1.2e-160 yisR K Transcriptional regulator
EFDNPGAD_00844 4e-243 yisQ V Mate efflux family protein
EFDNPGAD_00845 6.8e-150 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
EFDNPGAD_00846 2.1e-88 yizA S Damage-inducible protein DinB
EFDNPGAD_00847 0.0 asnO 6.3.5.4 E Asparagine synthase
EFDNPGAD_00848 7.2e-106 yisN S Protein of unknown function (DUF2777)
EFDNPGAD_00849 0.0 wprA O Belongs to the peptidase S8 family
EFDNPGAD_00850 3e-57 yisL S UPF0344 protein
EFDNPGAD_00851 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
EFDNPGAD_00852 1.7e-176 cotH M Spore Coat
EFDNPGAD_00853 1.5e-22 yisI S Spo0E like sporulation regulatory protein
EFDNPGAD_00854 1.9e-33 gerPA S Spore germination protein
EFDNPGAD_00855 4e-34 gerPB S cell differentiation
EFDNPGAD_00856 1.8e-54 gerPC S Spore germination protein
EFDNPGAD_00857 6.3e-24 gerPD S Spore germination protein
EFDNPGAD_00858 3e-66 gerPE S Spore germination protein GerPE
EFDNPGAD_00859 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
EFDNPGAD_00860 6e-51 yisB V COG1403 Restriction endonuclease
EFDNPGAD_00861 0.0 sbcC L COG0419 ATPase involved in DNA repair
EFDNPGAD_00862 1.7e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EFDNPGAD_00863 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
EFDNPGAD_00864 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
EFDNPGAD_00865 2.2e-78 yhjR S Rubrerythrin
EFDNPGAD_00866 2e-36 yhjQ C COG1145 Ferredoxin
EFDNPGAD_00867 0.0 S Sugar transport-related sRNA regulator N-term
EFDNPGAD_00868 3.1e-215 EGP Transmembrane secretion effector
EFDNPGAD_00869 3.8e-202 abrB S membrane
EFDNPGAD_00870 1.6e-188 yhjM 5.1.1.1 K Transcriptional regulator
EFDNPGAD_00871 4.4e-255 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
EFDNPGAD_00872 1.8e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
EFDNPGAD_00873 1.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
EFDNPGAD_00874 6.9e-215 glcP G Major Facilitator Superfamily
EFDNPGAD_00875 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
EFDNPGAD_00876 1.1e-286 yhjG CH FAD binding domain
EFDNPGAD_00877 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
EFDNPGAD_00878 9.1e-110 yhjE S SNARE associated Golgi protein
EFDNPGAD_00879 5e-60 yhjD
EFDNPGAD_00880 6.9e-27 yhjC S Protein of unknown function (DUF3311)
EFDNPGAD_00881 6.1e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EFDNPGAD_00882 7.8e-42 yhjA S Excalibur calcium-binding domain
EFDNPGAD_00883 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
EFDNPGAD_00884 4.2e-109 comK K Competence transcription factor
EFDNPGAD_00885 1.3e-32 yhzC S IDEAL
EFDNPGAD_00886 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EFDNPGAD_00887 1.1e-302 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
EFDNPGAD_00888 1.7e-182 hemAT NT chemotaxis protein
EFDNPGAD_00889 5e-91 bioY S BioY family
EFDNPGAD_00890 1e-281 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
EFDNPGAD_00891 2.3e-201 vraB 2.3.1.9 I Belongs to the thiolase family
EFDNPGAD_00892 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
EFDNPGAD_00893 4.3e-159 yfmC M Periplasmic binding protein
EFDNPGAD_00894 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
EFDNPGAD_00895 9.2e-80 VY92_01935 K acetyltransferase
EFDNPGAD_00896 2.3e-204 aprE 3.4.21.62 O Belongs to the peptidase S8 family
EFDNPGAD_00897 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
EFDNPGAD_00898 1.9e-65 yhfM
EFDNPGAD_00899 7.3e-302 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
EFDNPGAD_00900 2.6e-112 yhfK GM NmrA-like family
EFDNPGAD_00901 2e-191 lplJ 6.3.1.20 H Lipoate-protein ligase
EFDNPGAD_00902 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
EFDNPGAD_00903 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EFDNPGAD_00904 1.7e-72 3.4.13.21 S ASCH
EFDNPGAD_00905 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
EFDNPGAD_00906 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
EFDNPGAD_00907 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EFDNPGAD_00908 1e-238 yhgE S YhgE Pip N-terminal domain protein
EFDNPGAD_00909 1.4e-101 yhgD K Transcriptional regulator
EFDNPGAD_00910 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EFDNPGAD_00911 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
EFDNPGAD_00912 1.7e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EFDNPGAD_00913 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EFDNPGAD_00914 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
EFDNPGAD_00915 7.5e-17 1.15.1.2 C Rubrerythrin
EFDNPGAD_00916 4.2e-248 yhfA C membrane
EFDNPGAD_00917 2.3e-231 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EFDNPGAD_00918 4.8e-115 ecsC S EcsC protein family
EFDNPGAD_00919 1.8e-215 ecsB U ABC transporter
EFDNPGAD_00920 4.6e-137 ecsA V transporter (ATP-binding protein)
EFDNPGAD_00921 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
EFDNPGAD_00922 9.9e-205 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EFDNPGAD_00923 3.6e-80 trpP S Tryptophan transporter TrpP
EFDNPGAD_00924 7e-39 yhaH S YtxH-like protein
EFDNPGAD_00925 1e-113 hpr K Negative regulator of protease production and sporulation
EFDNPGAD_00926 1.3e-54 yhaI S Protein of unknown function (DUF1878)
EFDNPGAD_00927 8.7e-90 yhaK S Putative zincin peptidase
EFDNPGAD_00928 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EFDNPGAD_00929 1.6e-21 yhaL S Sporulation protein YhaL
EFDNPGAD_00930 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
EFDNPGAD_00931 0.0 yhaN L AAA domain
EFDNPGAD_00932 3.6e-227 yhaO L DNA repair exonuclease
EFDNPGAD_00933 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
EFDNPGAD_00934 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
EFDNPGAD_00935 1.1e-26 S YhzD-like protein
EFDNPGAD_00936 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
EFDNPGAD_00938 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
EFDNPGAD_00939 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
EFDNPGAD_00940 7.1e-294 hemZ H coproporphyrinogen III oxidase
EFDNPGAD_00941 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
EFDNPGAD_00942 3.1e-206 yhaZ L DNA alkylation repair enzyme
EFDNPGAD_00943 9.5e-48 yheA S Belongs to the UPF0342 family
EFDNPGAD_00944 6.7e-204 yheB S Belongs to the UPF0754 family
EFDNPGAD_00945 4.3e-216 yheC HJ YheC/D like ATP-grasp
EFDNPGAD_00946 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
EFDNPGAD_00947 1.3e-36 yheE S Family of unknown function (DUF5342)
EFDNPGAD_00948 6.3e-28 sspB S spore protein
EFDNPGAD_00949 3.7e-111 yheG GM NAD(P)H-binding
EFDNPGAD_00950 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
EFDNPGAD_00951 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
EFDNPGAD_00952 3.4e-84 nhaX T Belongs to the universal stress protein A family
EFDNPGAD_00953 2.2e-233 nhaC C Na H antiporter
EFDNPGAD_00954 1.1e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
EFDNPGAD_00955 1.7e-151 yheN G deacetylase
EFDNPGAD_00956 1.2e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
EFDNPGAD_00957 6.6e-204 yhdY M Mechanosensitive ion channel
EFDNPGAD_00959 3.3e-135 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
EFDNPGAD_00960 5.1e-66 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EFDNPGAD_00961 2.8e-47 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EFDNPGAD_00962 1.1e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
EFDNPGAD_00963 1.4e-223 yhdR 2.6.1.1 E Aminotransferase
EFDNPGAD_00964 4.1e-74 cueR K transcriptional
EFDNPGAD_00965 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
EFDNPGAD_00966 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EFDNPGAD_00967 1.5e-191 yhdN C Aldo keto reductase
EFDNPGAD_00968 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
EFDNPGAD_00969 6.6e-201 yhdL S Sigma factor regulator N-terminal
EFDNPGAD_00970 8.1e-45 yhdK S Sigma-M inhibitor protein
EFDNPGAD_00971 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EFDNPGAD_00972 3.7e-276 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EFDNPGAD_00973 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EFDNPGAD_00974 3.4e-250 yhdG E amino acid
EFDNPGAD_00975 4.9e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EFDNPGAD_00976 1.4e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
EFDNPGAD_00977 3.8e-162 citR K Transcriptional regulator
EFDNPGAD_00978 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
EFDNPGAD_00979 5.8e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
EFDNPGAD_00980 2.1e-276 ycgB S Stage V sporulation protein R
EFDNPGAD_00981 8.7e-239 ygxB M Conserved TM helix
EFDNPGAD_00982 3.5e-76 nsrR K Transcriptional regulator
EFDNPGAD_00983 7.9e-189 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
EFDNPGAD_00984 4.8e-54 yhdC S Protein of unknown function (DUF3889)
EFDNPGAD_00985 1.2e-38 yhdB S YhdB-like protein
EFDNPGAD_00986 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
EFDNPGAD_00987 1.1e-113 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EFDNPGAD_00988 5.5e-214 yhcY 2.7.13.3 T Histidine kinase
EFDNPGAD_00989 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
EFDNPGAD_00990 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EFDNPGAD_00991 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EFDNPGAD_00992 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
EFDNPGAD_00993 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EFDNPGAD_00994 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EFDNPGAD_00995 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EFDNPGAD_00996 4.6e-120 yhcW 5.4.2.6 S hydrolase
EFDNPGAD_00997 9.9e-68 yhcV S COG0517 FOG CBS domain
EFDNPGAD_00998 9.3e-68 yhcU S Family of unknown function (DUF5365)
EFDNPGAD_00999 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EFDNPGAD_01000 7.6e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
EFDNPGAD_01001 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
EFDNPGAD_01002 5.2e-100 yhcQ M Spore coat protein
EFDNPGAD_01003 2.5e-167 yhcP
EFDNPGAD_01004 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EFDNPGAD_01005 3.7e-44 yhcM
EFDNPGAD_01006 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EFDNPGAD_01007 1.2e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
EFDNPGAD_01008 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
EFDNPGAD_01009 1e-30 cspB K Cold-shock protein
EFDNPGAD_01010 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EFDNPGAD_01011 2.6e-166 yhcH V ABC transporter, ATP-binding protein
EFDNPGAD_01012 1.6e-123 yhcG V ABC transporter, ATP-binding protein
EFDNPGAD_01013 6.6e-60 yhcF K Transcriptional regulator
EFDNPGAD_01014 7.8e-55
EFDNPGAD_01015 2.8e-37 yhcC
EFDNPGAD_01016 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
EFDNPGAD_01017 3.1e-271 yhcA EGP Major facilitator Superfamily
EFDNPGAD_01018 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
EFDNPGAD_01019 2.2e-76 yhbI K DNA-binding transcription factor activity
EFDNPGAD_01020 2.5e-225 yhbH S Belongs to the UPF0229 family
EFDNPGAD_01021 0.0 prkA T Ser protein kinase
EFDNPGAD_01022 9.1e-74 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
EFDNPGAD_01023 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
EFDNPGAD_01024 1.2e-109 yhbD K Protein of unknown function (DUF4004)
EFDNPGAD_01025 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EFDNPGAD_01026 4.4e-177 yhbB S Putative amidase domain
EFDNPGAD_01027 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EFDNPGAD_01028 7.9e-114 yhzB S B3/4 domain
EFDNPGAD_01030 4.4e-29 K Transcriptional regulator
EFDNPGAD_01031 4.1e-78 ygaO
EFDNPGAD_01032 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EFDNPGAD_01034 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
EFDNPGAD_01035 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
EFDNPGAD_01036 1.7e-171 ssuA M Sulfonate ABC transporter
EFDNPGAD_01037 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
EFDNPGAD_01038 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
EFDNPGAD_01040 1.9e-266 ygaK C Berberine and berberine like
EFDNPGAD_01041 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EFDNPGAD_01042 5e-133 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
EFDNPGAD_01043 3e-27
EFDNPGAD_01044 2.7e-143 spo0M S COG4326 Sporulation control protein
EFDNPGAD_01048 2e-08
EFDNPGAD_01056 7.8e-08
EFDNPGAD_01061 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
EFDNPGAD_01062 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
EFDNPGAD_01063 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
EFDNPGAD_01064 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
EFDNPGAD_01065 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
EFDNPGAD_01067 0.0 htpG O Molecular chaperone. Has ATPase activity
EFDNPGAD_01068 2.3e-246 csbC EGP Major facilitator Superfamily
EFDNPGAD_01069 8.3e-48 yxcD S Protein of unknown function (DUF2653)
EFDNPGAD_01071 3.7e-176 iolS C Aldo keto reductase
EFDNPGAD_01072 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
EFDNPGAD_01073 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EFDNPGAD_01074 1.1e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
EFDNPGAD_01075 2.9e-179 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
EFDNPGAD_01076 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
EFDNPGAD_01077 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
EFDNPGAD_01078 1.3e-235 iolF EGP Major facilitator Superfamily
EFDNPGAD_01079 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
EFDNPGAD_01080 2.3e-167 iolH G Xylose isomerase-like TIM barrel
EFDNPGAD_01081 1.9e-139 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
EFDNPGAD_01082 5.4e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
EFDNPGAD_01083 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFDNPGAD_01084 1.3e-182 T PhoQ Sensor
EFDNPGAD_01085 9.4e-141 yxdL V ABC transporter, ATP-binding protein
EFDNPGAD_01086 0.0 yxdM V ABC transporter (permease)
EFDNPGAD_01087 1.5e-58 yxeA S Protein of unknown function (DUF1093)
EFDNPGAD_01088 6e-177 fhuD P ABC transporter
EFDNPGAD_01089 8.5e-69
EFDNPGAD_01090 1.9e-16 yxeD
EFDNPGAD_01091 1.3e-20 yxeE
EFDNPGAD_01094 6.2e-151 yidA S hydrolases of the HAD superfamily
EFDNPGAD_01095 8.8e-192 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
EFDNPGAD_01097 2.2e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EFDNPGAD_01098 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EFDNPGAD_01099 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
EFDNPGAD_01100 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
EFDNPGAD_01101 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
EFDNPGAD_01102 3.8e-215 yxeP 3.5.1.47 E hydrolase activity
EFDNPGAD_01103 2e-255 yxeQ S MmgE/PrpD family
EFDNPGAD_01104 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
EFDNPGAD_01105 3e-153 yxxB S Domain of Unknown Function (DUF1206)
EFDNPGAD_01106 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EFDNPGAD_01107 7e-116 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EFDNPGAD_01108 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EFDNPGAD_01109 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
EFDNPGAD_01110 6.1e-252 lysP E amino acid
EFDNPGAD_01111 8e-182 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
EFDNPGAD_01112 1.2e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
EFDNPGAD_01113 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EFDNPGAD_01114 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
EFDNPGAD_01115 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
EFDNPGAD_01116 6.3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
EFDNPGAD_01117 2.1e-21 S Domain of unknown function (DUF5082)
EFDNPGAD_01118 3.6e-39 yxiC S Family of unknown function (DUF5344)
EFDNPGAD_01119 0.0 S nuclease activity
EFDNPGAD_01120 2.2e-78 S SMI1 / KNR4 family
EFDNPGAD_01121 3.6e-51
EFDNPGAD_01122 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EFDNPGAD_01123 6.6e-281 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EFDNPGAD_01124 1.1e-72 yxiE T Belongs to the universal stress protein A family
EFDNPGAD_01125 2.9e-168 yxxF EG EamA-like transporter family
EFDNPGAD_01126 0.0 wapA M COG3209 Rhs family protein
EFDNPGAD_01127 1.5e-71 yxxG
EFDNPGAD_01128 1.7e-84
EFDNPGAD_01129 6.4e-63
EFDNPGAD_01130 3.7e-75 yxiG
EFDNPGAD_01131 4.9e-46
EFDNPGAD_01132 3.8e-81
EFDNPGAD_01133 1.2e-96 yxiI S Protein of unknown function (DUF2716)
EFDNPGAD_01134 1.6e-48 yxiJ S YxiJ-like protein
EFDNPGAD_01137 7.5e-219 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
EFDNPGAD_01138 1e-265 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
EFDNPGAD_01139 3e-232 yxiO S COG2270 Permeases of the major facilitator superfamily
EFDNPGAD_01140 6.6e-114
EFDNPGAD_01141 8.3e-151 licT K transcriptional antiterminator
EFDNPGAD_01142 5e-144 exoK GH16 M licheninase activity
EFDNPGAD_01143 6.6e-224 citH C Citrate transporter
EFDNPGAD_01144 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
EFDNPGAD_01145 2.7e-48 yxiS
EFDNPGAD_01146 1.2e-22 T Domain of unknown function (DUF4163)
EFDNPGAD_01147 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EFDNPGAD_01148 2.2e-145 rlmA 2.1.1.187 Q Methyltransferase domain
EFDNPGAD_01149 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
EFDNPGAD_01150 1.4e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EFDNPGAD_01151 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EFDNPGAD_01152 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
EFDNPGAD_01153 1e-220 yxjG 2.1.1.14 E Methionine synthase
EFDNPGAD_01154 5.5e-222 yxjG 2.1.1.14 E Methionine synthase
EFDNPGAD_01155 1e-87 yxjI S LURP-one-related
EFDNPGAD_01158 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
EFDNPGAD_01159 8.9e-116 K helix_turn_helix, Lux Regulon
EFDNPGAD_01160 1.5e-193 yxjM T Signal transduction histidine kinase
EFDNPGAD_01161 2.4e-78 S Protein of unknown function (DUF1453)
EFDNPGAD_01162 1.9e-166 yxjO K LysR substrate binding domain
EFDNPGAD_01163 1.3e-95 yxkA S Phosphatidylethanolamine-binding protein
EFDNPGAD_01164 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EFDNPGAD_01165 4.1e-73 yxkC S Domain of unknown function (DUF4352)
EFDNPGAD_01166 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
EFDNPGAD_01167 2.5e-275 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EFDNPGAD_01168 4.8e-165 lrp QT PucR C-terminal helix-turn-helix domain
EFDNPGAD_01169 5.9e-205 msmK P Belongs to the ABC transporter superfamily
EFDNPGAD_01170 3e-156 yxkH G Polysaccharide deacetylase
EFDNPGAD_01172 0.0 3.4.24.84 O Peptidase family M48
EFDNPGAD_01173 1.5e-229 cimH C COG3493 Na citrate symporter
EFDNPGAD_01174 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
EFDNPGAD_01175 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
EFDNPGAD_01176 0.0 cydD V ATP-binding
EFDNPGAD_01177 0.0 cydD V ATP-binding protein
EFDNPGAD_01178 8e-162 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EFDNPGAD_01179 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
EFDNPGAD_01180 4.7e-91 sigY K Belongs to the sigma-70 factor family. ECF subfamily
EFDNPGAD_01181 3.9e-48 yxlC S Family of unknown function (DUF5345)
EFDNPGAD_01182 1.2e-31
EFDNPGAD_01183 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
EFDNPGAD_01184 5.1e-167 yxlF V ABC transporter, ATP-binding protein
EFDNPGAD_01185 1.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EFDNPGAD_01186 2.1e-216 yxlH EGP Major facilitator Superfamily
EFDNPGAD_01187 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
EFDNPGAD_01188 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
EFDNPGAD_01189 1.1e-19 yxzF
EFDNPGAD_01190 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
EFDNPGAD_01191 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
EFDNPGAD_01192 7.4e-250 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EFDNPGAD_01193 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
EFDNPGAD_01194 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EFDNPGAD_01195 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
EFDNPGAD_01196 6.6e-139 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
EFDNPGAD_01197 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EFDNPGAD_01198 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EFDNPGAD_01199 1.2e-232 dltB M membrane protein involved in D-alanine export
EFDNPGAD_01200 7.9e-293 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EFDNPGAD_01201 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
EFDNPGAD_01202 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
EFDNPGAD_01203 1.4e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
EFDNPGAD_01204 4.4e-233 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EFDNPGAD_01205 8.1e-88 ywaE K Transcriptional regulator
EFDNPGAD_01206 1.7e-128 ywaF S Integral membrane protein
EFDNPGAD_01207 7e-169 gspA M General stress
EFDNPGAD_01208 4e-153 sacY K transcriptional antiterminator
EFDNPGAD_01209 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EFDNPGAD_01210 1.6e-277 epr 3.4.21.62 O Belongs to the peptidase S8 family
EFDNPGAD_01211 5.8e-247 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EFDNPGAD_01212 1.8e-127 ywbB S Protein of unknown function (DUF2711)
EFDNPGAD_01213 4.4e-67 ywbC 4.4.1.5 E glyoxalase
EFDNPGAD_01214 8.9e-223 ywbD 2.1.1.191 J Methyltransferase
EFDNPGAD_01215 1.2e-28 ywbE S Uncharacterized conserved protein (DUF2196)
EFDNPGAD_01216 1.9e-209 ywbF EGP Major facilitator Superfamily
EFDNPGAD_01217 2.3e-111 ywbG M effector of murein hydrolase
EFDNPGAD_01218 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
EFDNPGAD_01219 4.3e-153 ywbI K Transcriptional regulator
EFDNPGAD_01220 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EFDNPGAD_01221 4.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
EFDNPGAD_01222 8.2e-255 P COG0672 High-affinity Fe2 Pb2 permease
EFDNPGAD_01223 2e-187 ycdO P periplasmic lipoprotein involved in iron transport
EFDNPGAD_01224 2.6e-225 ywbN P Dyp-type peroxidase family protein
EFDNPGAD_01225 1.9e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
EFDNPGAD_01226 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EFDNPGAD_01227 9.8e-49 ywcB S Protein of unknown function, DUF485
EFDNPGAD_01229 2.2e-122 ywcC K transcriptional regulator
EFDNPGAD_01230 9.5e-60 gtcA S GtrA-like protein
EFDNPGAD_01231 6.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EFDNPGAD_01232 3.7e-306 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
EFDNPGAD_01233 1e-35 ywzA S membrane
EFDNPGAD_01234 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
EFDNPGAD_01235 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EFDNPGAD_01236 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
EFDNPGAD_01237 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
EFDNPGAD_01238 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
EFDNPGAD_01239 2.9e-202 rodA D Belongs to the SEDS family
EFDNPGAD_01240 7.2e-138 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
EFDNPGAD_01241 5.1e-187 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EFDNPGAD_01242 0.0 vpr O Belongs to the peptidase S8 family
EFDNPGAD_01244 2.4e-150 sacT K transcriptional antiterminator
EFDNPGAD_01245 1e-139 focA P Formate/nitrite transporter
EFDNPGAD_01246 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EFDNPGAD_01247 9.5e-296 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
EFDNPGAD_01248 2e-28 ywdA
EFDNPGAD_01249 9.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
EFDNPGAD_01250 1.3e-57 pex K Transcriptional regulator PadR-like family
EFDNPGAD_01251 1.4e-113 ywdD
EFDNPGAD_01253 1.1e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
EFDNPGAD_01254 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EFDNPGAD_01255 5.9e-263 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
EFDNPGAD_01256 7.7e-49 ywdI S Family of unknown function (DUF5327)
EFDNPGAD_01257 1.3e-238 ywdJ F Xanthine uracil
EFDNPGAD_01258 4.3e-59 ywdK S small membrane protein
EFDNPGAD_01259 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
EFDNPGAD_01260 2.8e-145 spsA M Spore Coat
EFDNPGAD_01261 1.5e-269 spsB M Capsule polysaccharide biosynthesis protein
EFDNPGAD_01262 1.6e-224 spsC E Belongs to the DegT DnrJ EryC1 family
EFDNPGAD_01263 4e-164 spsD 2.3.1.210 K Spore Coat
EFDNPGAD_01264 3.2e-214 spsE 2.5.1.56 M acid synthase
EFDNPGAD_01265 9.7e-132 spsF M Spore Coat
EFDNPGAD_01266 1.7e-190 spsG M Spore Coat
EFDNPGAD_01267 1.9e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EFDNPGAD_01268 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EFDNPGAD_01269 5.3e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EFDNPGAD_01270 3.5e-87 spsL 5.1.3.13 M Spore Coat
EFDNPGAD_01271 1.8e-78
EFDNPGAD_01272 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
EFDNPGAD_01273 1.4e-297 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
EFDNPGAD_01274 0.0 rocB E arginine degradation protein
EFDNPGAD_01275 4e-262 lysP E amino acid
EFDNPGAD_01276 4.6e-206 ywfA EGP Major facilitator Superfamily
EFDNPGAD_01277 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
EFDNPGAD_01278 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
EFDNPGAD_01279 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EFDNPGAD_01280 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
EFDNPGAD_01281 2.9e-210 bacE EGP Major facilitator Superfamily
EFDNPGAD_01282 2.7e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
EFDNPGAD_01283 4e-139 IQ Enoyl-(Acyl carrier protein) reductase
EFDNPGAD_01284 1.1e-146 ywfI C May function as heme-dependent peroxidase
EFDNPGAD_01285 6.6e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
EFDNPGAD_01286 9.2e-164 cysL K Transcriptional regulator
EFDNPGAD_01287 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
EFDNPGAD_01288 5.2e-159 ywfM EG EamA-like transporter family
EFDNPGAD_01289 1.6e-111 rsfA_1
EFDNPGAD_01290 3.1e-36 ywzC S Belongs to the UPF0741 family
EFDNPGAD_01291 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
EFDNPGAD_01292 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
EFDNPGAD_01293 2.8e-79 yffB K Transcriptional regulator
EFDNPGAD_01294 2.6e-242 mmr U Major Facilitator Superfamily
EFDNPGAD_01296 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EFDNPGAD_01297 3.3e-71 ywhA K Transcriptional regulator
EFDNPGAD_01298 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
EFDNPGAD_01299 5.1e-119 ywhC S Peptidase family M50
EFDNPGAD_01300 5.2e-95 ywhD S YwhD family
EFDNPGAD_01301 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EFDNPGAD_01302 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EFDNPGAD_01303 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
EFDNPGAD_01304 1e-84 ywhH S Aminoacyl-tRNA editing domain
EFDNPGAD_01306 2.3e-79 S aspartate phosphatase
EFDNPGAD_01307 2.5e-205 ywhK CO amine dehydrogenase activity
EFDNPGAD_01308 2.9e-249 ywhL CO amine dehydrogenase activity
EFDNPGAD_01310 1.2e-249 L Peptidase, M16
EFDNPGAD_01311 2.7e-219 2.7.1.26, 2.7.7.2 L Peptidase, M16
EFDNPGAD_01312 3.1e-237 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
EFDNPGAD_01313 3.3e-132 cbiO V ABC transporter
EFDNPGAD_01315 2.6e-271 C Fe-S oxidoreductases
EFDNPGAD_01316 1e-07 S Bacteriocin subtilosin A
EFDNPGAD_01317 4.7e-73 ywiB S protein conserved in bacteria
EFDNPGAD_01318 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
EFDNPGAD_01319 9.8e-214 narK P COG2223 Nitrate nitrite transporter
EFDNPGAD_01320 5.3e-130 fnr K helix_turn_helix, cAMP Regulatory protein
EFDNPGAD_01321 4.3e-140 ywiC S YwiC-like protein
EFDNPGAD_01322 7e-86 arfM T cyclic nucleotide binding
EFDNPGAD_01323 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EFDNPGAD_01324 1e-297 narH 1.7.5.1 C Nitrate reductase, beta
EFDNPGAD_01325 4.1e-98 narJ 1.7.5.1 C nitrate reductase
EFDNPGAD_01326 1.8e-124 narI 1.7.5.1 C nitrate reductase, gamma
EFDNPGAD_01327 6.4e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EFDNPGAD_01328 0.0 ywjA V ABC transporter
EFDNPGAD_01329 4.8e-96 ywjB H RibD C-terminal domain
EFDNPGAD_01330 2.7e-42 ywjC
EFDNPGAD_01331 6.6e-184 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
EFDNPGAD_01332 2.3e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
EFDNPGAD_01333 0.0 fadF C COG0247 Fe-S oxidoreductase
EFDNPGAD_01334 2.6e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
EFDNPGAD_01335 1.5e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EFDNPGAD_01336 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EFDNPGAD_01337 2.4e-92 ywjG S Domain of unknown function (DUF2529)
EFDNPGAD_01338 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
EFDNPGAD_01339 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
EFDNPGAD_01340 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EFDNPGAD_01341 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EFDNPGAD_01342 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
EFDNPGAD_01343 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EFDNPGAD_01344 1.1e-32 rpmE J Binds the 23S rRNA
EFDNPGAD_01345 2.4e-104 tdk 2.7.1.21 F thymidine kinase
EFDNPGAD_01346 0.0 sfcA 1.1.1.38 C malic enzyme
EFDNPGAD_01347 8.6e-160 ywkB S Membrane transport protein
EFDNPGAD_01348 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
EFDNPGAD_01349 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EFDNPGAD_01350 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EFDNPGAD_01351 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EFDNPGAD_01353 3.4e-56 ywlA S Uncharacterised protein family (UPF0715)
EFDNPGAD_01354 6.1e-112 spoIIR S stage II sporulation protein R
EFDNPGAD_01355 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
EFDNPGAD_01356 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EFDNPGAD_01357 1.7e-91 mntP P Probably functions as a manganese efflux pump
EFDNPGAD_01358 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EFDNPGAD_01359 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
EFDNPGAD_01360 7.2e-95 ywlG S Belongs to the UPF0340 family
EFDNPGAD_01361 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EFDNPGAD_01362 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EFDNPGAD_01363 2.5e-62 atpI S ATP synthase
EFDNPGAD_01364 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
EFDNPGAD_01365 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EFDNPGAD_01366 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EFDNPGAD_01367 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EFDNPGAD_01368 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EFDNPGAD_01369 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EFDNPGAD_01370 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EFDNPGAD_01371 5.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
EFDNPGAD_01372 4.3e-88 ywmA
EFDNPGAD_01373 1.3e-32 ywzB S membrane
EFDNPGAD_01374 1.6e-134 ywmB S TATA-box binding
EFDNPGAD_01375 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EFDNPGAD_01376 2e-178 spoIID D Stage II sporulation protein D
EFDNPGAD_01377 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
EFDNPGAD_01378 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
EFDNPGAD_01380 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EFDNPGAD_01381 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EFDNPGAD_01382 1.3e-103 S response regulator aspartate phosphatase
EFDNPGAD_01383 3e-84 ywmF S Peptidase M50
EFDNPGAD_01384 3.8e-11 csbD K CsbD-like
EFDNPGAD_01386 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
EFDNPGAD_01387 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
EFDNPGAD_01388 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
EFDNPGAD_01389 1.7e-64 ywnA K Transcriptional regulator
EFDNPGAD_01390 1.6e-114 ywnB S NAD(P)H-binding
EFDNPGAD_01391 2.6e-59 ywnC S Family of unknown function (DUF5362)
EFDNPGAD_01392 4.1e-144 mta K transcriptional
EFDNPGAD_01393 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EFDNPGAD_01394 2.2e-70 ywnF S Family of unknown function (DUF5392)
EFDNPGAD_01395 2.7e-14 ywnC S Family of unknown function (DUF5362)
EFDNPGAD_01396 6.4e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
EFDNPGAD_01397 5.5e-126 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
EFDNPGAD_01398 3.5e-73 ywnJ S VanZ like family
EFDNPGAD_01399 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
EFDNPGAD_01400 1.6e-58 nrgB K Belongs to the P(II) protein family
EFDNPGAD_01401 2.5e-225 amt P Ammonium transporter
EFDNPGAD_01402 1.2e-77
EFDNPGAD_01403 4e-104 phzA Q Isochorismatase family
EFDNPGAD_01404 4.4e-242 ywoD EGP Major facilitator superfamily
EFDNPGAD_01405 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
EFDNPGAD_01406 1.2e-231 ywoF P Right handed beta helix region
EFDNPGAD_01407 2.7e-211 ywoG EGP Major facilitator Superfamily
EFDNPGAD_01408 2.1e-70 ywoH K COG1846 Transcriptional regulators
EFDNPGAD_01409 3e-44 spoIIID K Stage III sporulation protein D
EFDNPGAD_01410 3.5e-180 mbl D Rod shape-determining protein
EFDNPGAD_01411 6.9e-126 flhO N flagellar basal body
EFDNPGAD_01412 1.5e-141 flhP N flagellar basal body
EFDNPGAD_01413 2.1e-199 S aspartate phosphatase
EFDNPGAD_01414 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EFDNPGAD_01415 1.5e-54 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EFDNPGAD_01416 1.4e-153 ywpD T Histidine kinase
EFDNPGAD_01417 8e-51 srtA 3.4.22.70 M Sortase family
EFDNPGAD_01418 1.1e-66 ywpF S YwpF-like protein
EFDNPGAD_01419 1.3e-66 ywpG
EFDNPGAD_01420 9.8e-58 ssbB L Single-stranded DNA-binding protein
EFDNPGAD_01421 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
EFDNPGAD_01422 3.6e-157 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
EFDNPGAD_01423 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
EFDNPGAD_01424 3.8e-309 ywqB S SWIM zinc finger
EFDNPGAD_01425 1.2e-17
EFDNPGAD_01426 2e-116 ywqC M biosynthesis protein
EFDNPGAD_01427 1.1e-119 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
EFDNPGAD_01428 1.4e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
EFDNPGAD_01429 3e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EFDNPGAD_01430 3.4e-154 ywqG S Domain of unknown function (DUF1963)
EFDNPGAD_01431 3.3e-15 S Domain of unknown function (DUF5082)
EFDNPGAD_01432 1.3e-38 ywqI S Family of unknown function (DUF5344)
EFDNPGAD_01433 0.0 ywqJ L nucleic acid phosphodiester bond hydrolysis
EFDNPGAD_01434 1.7e-52 S MORN repeat variant
EFDNPGAD_01435 4.5e-137 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
EFDNPGAD_01436 2.9e-162 K Transcriptional regulator
EFDNPGAD_01437 2.7e-102 ywqN S NAD(P)H-dependent
EFDNPGAD_01439 6.9e-90 ywrA P COG2059 Chromate transport protein ChrA
EFDNPGAD_01440 2.4e-104 ywrB P Chromate transporter
EFDNPGAD_01441 2.1e-82 ywrC K Transcriptional regulator
EFDNPGAD_01442 9.6e-310 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
EFDNPGAD_01443 2.9e-54 S Domain of unknown function (DUF4181)
EFDNPGAD_01444 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EFDNPGAD_01445 3.7e-12
EFDNPGAD_01446 1.2e-210 cotH M Spore Coat
EFDNPGAD_01447 7.6e-131 cotB
EFDNPGAD_01448 7.5e-126 ywrJ
EFDNPGAD_01449 1.9e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EFDNPGAD_01450 1.1e-169 alsR K LysR substrate binding domain
EFDNPGAD_01451 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
EFDNPGAD_01452 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
EFDNPGAD_01453 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
EFDNPGAD_01454 3.6e-48 ywsA S Protein of unknown function (DUF3892)
EFDNPGAD_01455 4.6e-94 batE T Sh3 type 3 domain protein
EFDNPGAD_01456 4.4e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
EFDNPGAD_01457 1.4e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
EFDNPGAD_01458 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
EFDNPGAD_01459 2.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
EFDNPGAD_01460 2.9e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EFDNPGAD_01461 1.9e-178 rbsR K transcriptional
EFDNPGAD_01462 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
EFDNPGAD_01463 8.6e-70 pgsC S biosynthesis protein
EFDNPGAD_01464 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
EFDNPGAD_01465 3.6e-21 ywtC
EFDNPGAD_01466 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EFDNPGAD_01467 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
EFDNPGAD_01468 8.4e-171 ywtF K Transcriptional regulator
EFDNPGAD_01469 1.9e-248 ywtG EGP Major facilitator Superfamily
EFDNPGAD_01470 7.6e-216 gerAC S Spore germination protein
EFDNPGAD_01471 7.5e-200 gerBB E Spore germination protein
EFDNPGAD_01472 3.5e-266 gerBA EG Spore germination protein
EFDNPGAD_01473 7.1e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
EFDNPGAD_01474 7.2e-217 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EFDNPGAD_01475 1.2e-260
EFDNPGAD_01476 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EFDNPGAD_01477 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
EFDNPGAD_01478 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
EFDNPGAD_01479 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
EFDNPGAD_01480 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EFDNPGAD_01481 1.1e-150 tagG GM Transport permease protein
EFDNPGAD_01482 1.8e-279 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
EFDNPGAD_01483 1.6e-100 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
EFDNPGAD_01485 8.1e-257 ggaA M Glycosyltransferase like family 2
EFDNPGAD_01486 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
EFDNPGAD_01487 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
EFDNPGAD_01488 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
EFDNPGAD_01489 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
EFDNPGAD_01490 6e-38
EFDNPGAD_01491 0.0 lytB 3.5.1.28 D Stage II sporulation protein
EFDNPGAD_01492 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EFDNPGAD_01493 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EFDNPGAD_01494 3.3e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EFDNPGAD_01495 7.4e-222 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
EFDNPGAD_01496 2.4e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EFDNPGAD_01497 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
EFDNPGAD_01498 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
EFDNPGAD_01499 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
EFDNPGAD_01500 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
EFDNPGAD_01501 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
EFDNPGAD_01502 6e-163 yvhJ K Transcriptional regulator
EFDNPGAD_01503 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
EFDNPGAD_01504 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
EFDNPGAD_01505 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EFDNPGAD_01506 7.3e-155 degV S protein conserved in bacteria
EFDNPGAD_01507 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EFDNPGAD_01508 5.7e-46 comFB S Late competence development protein ComFB
EFDNPGAD_01509 2.7e-129 comFC S Phosphoribosyl transferase domain
EFDNPGAD_01510 7e-74 yvyF S flagellar protein
EFDNPGAD_01511 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
EFDNPGAD_01512 2.4e-78 flgN NOU FlgN protein
EFDNPGAD_01513 5.9e-264 flgK N flagellar hook-associated protein
EFDNPGAD_01514 1.1e-156 flgL N Belongs to the bacterial flagellin family
EFDNPGAD_01515 2.6e-50 yviE
EFDNPGAD_01516 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
EFDNPGAD_01517 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EFDNPGAD_01518 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EFDNPGAD_01519 6.1e-57 flaG N flagellar protein FlaG
EFDNPGAD_01520 1.3e-266 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EFDNPGAD_01521 2.9e-69 fliS N flagellar protein FliS
EFDNPGAD_01522 1.9e-08 fliT S bacterial-type flagellum organization
EFDNPGAD_01523 2.8e-66
EFDNPGAD_01524 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EFDNPGAD_01525 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EFDNPGAD_01526 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EFDNPGAD_01527 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
EFDNPGAD_01528 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
EFDNPGAD_01529 1.6e-123 ftsE D cell division ATP-binding protein FtsE
EFDNPGAD_01530 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
EFDNPGAD_01531 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
EFDNPGAD_01532 5.3e-56 swrA S Swarming motility protein
EFDNPGAD_01533 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EFDNPGAD_01534 7.9e-228 yvkA EGP Major facilitator Superfamily
EFDNPGAD_01535 7e-101 yvkB K Transcriptional regulator
EFDNPGAD_01536 0.0 yvkC 2.7.9.2 GT Phosphotransferase
EFDNPGAD_01537 1.2e-30 csbA S protein conserved in bacteria
EFDNPGAD_01538 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EFDNPGAD_01539 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EFDNPGAD_01540 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EFDNPGAD_01541 6.7e-34 yvkN
EFDNPGAD_01542 8e-49 yvlA
EFDNPGAD_01543 3.4e-168 yvlB S Putative adhesin
EFDNPGAD_01544 2.6e-26 pspB KT PspC domain
EFDNPGAD_01545 1.2e-50 yvlD S Membrane
EFDNPGAD_01546 2.7e-203 yvmA EGP Major facilitator Superfamily
EFDNPGAD_01547 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
EFDNPGAD_01548 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
EFDNPGAD_01549 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
EFDNPGAD_01550 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
EFDNPGAD_01551 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
EFDNPGAD_01552 3.6e-134 yvoA K transcriptional
EFDNPGAD_01553 8.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EFDNPGAD_01554 6.8e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
EFDNPGAD_01555 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EFDNPGAD_01556 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EFDNPGAD_01557 1.5e-164 yvoD P COG0370 Fe2 transport system protein B
EFDNPGAD_01558 1.3e-119 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
EFDNPGAD_01559 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
EFDNPGAD_01560 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
EFDNPGAD_01561 4.5e-140 yvpB NU protein conserved in bacteria
EFDNPGAD_01562 4.8e-221 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EFDNPGAD_01563 1.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
EFDNPGAD_01564 6.6e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EFDNPGAD_01565 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
EFDNPGAD_01566 1.7e-116 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EFDNPGAD_01567 3.1e-133 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EFDNPGAD_01568 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EFDNPGAD_01569 8e-114 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
EFDNPGAD_01570 4.6e-121
EFDNPGAD_01571 0.0
EFDNPGAD_01573 0.0 msbA2 3.6.3.44 V ABC transporter
EFDNPGAD_01574 2.4e-278 S COG0457 FOG TPR repeat
EFDNPGAD_01575 1.4e-102 usp CBM50 M protein conserved in bacteria
EFDNPGAD_01576 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EFDNPGAD_01577 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
EFDNPGAD_01578 5.7e-166 rapZ S Displays ATPase and GTPase activities
EFDNPGAD_01579 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
EFDNPGAD_01580 1.4e-170 whiA K May be required for sporulation
EFDNPGAD_01581 1.6e-36 crh G Phosphocarrier protein Chr
EFDNPGAD_01582 8.6e-147 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
EFDNPGAD_01583 1.8e-33
EFDNPGAD_01584 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFDNPGAD_01585 2.3e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
EFDNPGAD_01586 5.6e-141 yvcR V ABC transporter, ATP-binding protein
EFDNPGAD_01587 0.0 yxdM V ABC transporter (permease)
EFDNPGAD_01588 1.3e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EFDNPGAD_01589 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
EFDNPGAD_01590 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
EFDNPGAD_01591 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
EFDNPGAD_01592 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
EFDNPGAD_01593 3.6e-174 yvdE K Transcriptional regulator
EFDNPGAD_01594 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
EFDNPGAD_01595 1.3e-235 mdxE G COG2182 Maltose-binding periplasmic proteins domains
EFDNPGAD_01596 5.3e-245 malC P COG1175 ABC-type sugar transport systems, permease components
EFDNPGAD_01597 7.8e-149 malD P transport
EFDNPGAD_01598 1.2e-158 malA S Protein of unknown function (DUF1189)
EFDNPGAD_01599 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
EFDNPGAD_01600 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
EFDNPGAD_01601 1.3e-122 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
EFDNPGAD_01602 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EFDNPGAD_01604 1.5e-183 S Patatin-like phospholipase
EFDNPGAD_01605 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
EFDNPGAD_01606 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
EFDNPGAD_01607 4.1e-50 sugE P Small Multidrug Resistance protein
EFDNPGAD_01608 6.7e-51 ykkC P Small Multidrug Resistance protein
EFDNPGAD_01609 2.6e-106 yvdT K Transcriptional regulator
EFDNPGAD_01610 1.5e-294 yveA E amino acid
EFDNPGAD_01611 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
EFDNPGAD_01612 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
EFDNPGAD_01613 9.6e-266 pbpE V Beta-lactamase
EFDNPGAD_01614 3.1e-127 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
EFDNPGAD_01615 1.3e-48 MA20_18690 S Protein of unknown function (DUF3237)
EFDNPGAD_01616 4.6e-93 padC Q Phenolic acid decarboxylase
EFDNPGAD_01618 4.8e-287 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
EFDNPGAD_01619 5.7e-77 slr K transcriptional
EFDNPGAD_01620 4e-122 ywqC M biosynthesis protein
EFDNPGAD_01621 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
EFDNPGAD_01622 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
EFDNPGAD_01623 2e-224 epsD GT4 M Glycosyl transferase 4-like
EFDNPGAD_01624 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EFDNPGAD_01625 5.3e-220 epsF GT4 M Glycosyl transferases group 1
EFDNPGAD_01626 4.8e-207 epsG S EpsG family
EFDNPGAD_01627 3.6e-196 epsH GT2 S Glycosyltransferase like family 2
EFDNPGAD_01628 3.6e-207 epsI GM pyruvyl transferase
EFDNPGAD_01629 1.9e-197 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
EFDNPGAD_01630 8.9e-260 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EFDNPGAD_01631 2.6e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EFDNPGAD_01632 2.2e-58 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
EFDNPGAD_01633 1.2e-224 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
EFDNPGAD_01634 5.8e-188 yvfF GM Exopolysaccharide biosynthesis protein
EFDNPGAD_01635 1e-31 yvfG S YvfG protein
EFDNPGAD_01636 6.5e-243 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
EFDNPGAD_01637 1.4e-309 yvfH C L-lactate permease
EFDNPGAD_01638 1e-112 yvfI K COG2186 Transcriptional regulators
EFDNPGAD_01639 1.8e-184 lacR K Transcriptional regulator
EFDNPGAD_01640 2.9e-232 cycB G COG2182 Maltose-binding periplasmic proteins domains
EFDNPGAD_01641 1.3e-232 malC P COG1175 ABC-type sugar transport systems, permease components
EFDNPGAD_01642 3.2e-150 ganQ P transport
EFDNPGAD_01643 0.0 lacA 3.2.1.23 G beta-galactosidase
EFDNPGAD_01644 2.6e-252 galA 3.2.1.89 G arabinogalactan
EFDNPGAD_01645 1.4e-199 rsbU 3.1.3.3 T response regulator
EFDNPGAD_01646 2.6e-157 rsbQ S Alpha/beta hydrolase family
EFDNPGAD_01647 3e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
EFDNPGAD_01648 6.2e-134 yvfS V COG0842 ABC-type multidrug transport system, permease component
EFDNPGAD_01649 8.9e-201 desK 2.7.13.3 T Histidine kinase
EFDNPGAD_01650 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EFDNPGAD_01651 1.5e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EFDNPGAD_01652 1.2e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
EFDNPGAD_01653 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EFDNPGAD_01654 4.3e-197 yvbX S Glycosyl hydrolase
EFDNPGAD_01655 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
EFDNPGAD_01656 8.5e-157 yvbV EG EamA-like transporter family
EFDNPGAD_01657 3.9e-159 yvbU K Transcriptional regulator
EFDNPGAD_01658 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EFDNPGAD_01659 5.5e-203 araR K transcriptional
EFDNPGAD_01660 1.6e-252 araE EGP Major facilitator Superfamily
EFDNPGAD_01661 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EFDNPGAD_01662 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EFDNPGAD_01663 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
EFDNPGAD_01664 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EFDNPGAD_01665 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
EFDNPGAD_01666 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EFDNPGAD_01667 7.7e-82 yvbK 3.1.3.25 K acetyltransferase
EFDNPGAD_01668 0.0 tcaA S response to antibiotic
EFDNPGAD_01669 4.2e-124 exoY M Membrane
EFDNPGAD_01670 8.6e-113 yvbH S YvbH-like oligomerisation region
EFDNPGAD_01671 6.4e-103 yvbG U UPF0056 membrane protein
EFDNPGAD_01672 1.4e-98 yvbF K Belongs to the GbsR family
EFDNPGAD_01673 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EFDNPGAD_01674 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
EFDNPGAD_01675 2.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EFDNPGAD_01676 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
EFDNPGAD_01677 4.5e-45 sdpR K transcriptional
EFDNPGAD_01678 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
EFDNPGAD_01679 4.4e-08
EFDNPGAD_01680 7.6e-172
EFDNPGAD_01681 7.9e-13 S Sporulation delaying protein SdpA
EFDNPGAD_01682 8.7e-61 yvbF K Belongs to the GbsR family
EFDNPGAD_01683 3e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EFDNPGAD_01684 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
EFDNPGAD_01685 1.1e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EFDNPGAD_01686 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
EFDNPGAD_01687 4.2e-226 NT chemotaxis protein
EFDNPGAD_01688 2.2e-54 yodB K transcriptional
EFDNPGAD_01689 8e-70 yvaO K Cro/C1-type HTH DNA-binding domain
EFDNPGAD_01690 4e-69 K transcriptional
EFDNPGAD_01691 7.5e-36 yvzC K Transcriptional
EFDNPGAD_01692 3.7e-153 yvaM S Serine aminopeptidase, S33
EFDNPGAD_01693 2.4e-23 secG U Preprotein translocase subunit SecG
EFDNPGAD_01694 5.6e-143 est 3.1.1.1 S Carboxylesterase
EFDNPGAD_01695 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EFDNPGAD_01696 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EFDNPGAD_01698 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EFDNPGAD_01699 4.1e-101 K Bacterial regulatory proteins, tetR family
EFDNPGAD_01700 2.8e-55 yvaE P Small Multidrug Resistance protein
EFDNPGAD_01701 5.7e-73 yvaD S Family of unknown function (DUF5360)
EFDNPGAD_01702 0.0 yvaC S Fusaric acid resistance protein-like
EFDNPGAD_01703 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EFDNPGAD_01704 2.1e-199 yvaA 1.1.1.371 S Oxidoreductase
EFDNPGAD_01705 2.2e-48 csoR S transcriptional
EFDNPGAD_01706 1.5e-29 copZ P Copper resistance protein CopZ
EFDNPGAD_01707 0.0 copA 3.6.3.54 P P-type ATPase
EFDNPGAD_01708 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
EFDNPGAD_01709 1.6e-104 bdbD O Thioredoxin
EFDNPGAD_01710 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
EFDNPGAD_01711 4.1e-107 yvgT S membrane
EFDNPGAD_01712 0.0 helD 3.6.4.12 L DNA helicase
EFDNPGAD_01713 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EFDNPGAD_01714 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
EFDNPGAD_01715 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
EFDNPGAD_01716 5.4e-86 yvgO
EFDNPGAD_01717 9.1e-158 yvgN S reductase
EFDNPGAD_01718 4.7e-120 modB P COG4149 ABC-type molybdate transport system, permease component
EFDNPGAD_01719 5.8e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
EFDNPGAD_01720 8e-171 yvgK P COG1910 Periplasmic molybdate-binding protein domain
EFDNPGAD_01721 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
EFDNPGAD_01722 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
EFDNPGAD_01723 6.5e-16 S Small spore protein J (Spore_SspJ)
EFDNPGAD_01724 2.6e-237 yvsH E Arginine ornithine antiporter
EFDNPGAD_01726 2.1e-179 fhuD P ABC transporter
EFDNPGAD_01727 9.3e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFDNPGAD_01728 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFDNPGAD_01729 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
EFDNPGAD_01730 4.8e-176 M Efflux transporter rnd family, mfp subunit
EFDNPGAD_01731 7.1e-124 macB V ABC transporter, ATP-binding protein
EFDNPGAD_01732 1.8e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
EFDNPGAD_01733 1.3e-64 yvrL S Regulatory protein YrvL
EFDNPGAD_01734 7.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
EFDNPGAD_01735 2.4e-19 S YvrJ protein family
EFDNPGAD_01736 1.8e-96 yvrI K RNA polymerase
EFDNPGAD_01737 3.6e-22
EFDNPGAD_01738 3.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFDNPGAD_01739 0.0 T PhoQ Sensor
EFDNPGAD_01740 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
EFDNPGAD_01741 6.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EFDNPGAD_01742 1.8e-170 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
EFDNPGAD_01743 7.7e-186 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFDNPGAD_01744 2.8e-249 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
EFDNPGAD_01745 6.5e-102 yvqK 2.5.1.17 S Adenosyltransferase
EFDNPGAD_01746 4.8e-227 yvqJ EGP Major facilitator Superfamily
EFDNPGAD_01747 5.6e-62 liaI S membrane
EFDNPGAD_01748 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
EFDNPGAD_01749 9.3e-129 liaG S Putative adhesin
EFDNPGAD_01750 5.6e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
EFDNPGAD_01751 5.5e-187 vraS 2.7.13.3 T Histidine kinase
EFDNPGAD_01752 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EFDNPGAD_01753 6e-189 gerAC S Spore germination B3/ GerAC like, C-terminal
EFDNPGAD_01754 9.1e-198 gerAB E Spore germination protein
EFDNPGAD_01755 3.7e-247 gerAA EG Spore germination protein
EFDNPGAD_01756 2.3e-24 S Protein of unknown function (DUF3970)
EFDNPGAD_01757 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EFDNPGAD_01758 4.3e-158 yuxN K Transcriptional regulator
EFDNPGAD_01759 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
EFDNPGAD_01760 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFDNPGAD_01761 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EFDNPGAD_01762 1.2e-79 dps P Ferritin-like domain
EFDNPGAD_01763 4.7e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EFDNPGAD_01764 3.9e-34 pepF2 E COG1164 Oligoendopeptidase F
EFDNPGAD_01765 6.3e-258 pepF2 E COG1164 Oligoendopeptidase F
EFDNPGAD_01766 5.6e-66 S YusW-like protein
EFDNPGAD_01767 1e-153 yusV 3.6.3.34 HP ABC transporter
EFDNPGAD_01768 3.8e-47 yusU S Protein of unknown function (DUF2573)
EFDNPGAD_01769 2.7e-160 yusT K LysR substrate binding domain
EFDNPGAD_01770 2.5e-50 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EFDNPGAD_01771 2.5e-62 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EFDNPGAD_01772 8.4e-66 yusQ S Tautomerase enzyme
EFDNPGAD_01773 3.8e-293 yusP P Major facilitator superfamily
EFDNPGAD_01774 5.4e-75 yusO K Iron dependent repressor, N-terminal DNA binding domain
EFDNPGAD_01775 3.2e-53 yusN M Coat F domain
EFDNPGAD_01776 5.1e-40
EFDNPGAD_01777 2.2e-165 fadM E Proline dehydrogenase
EFDNPGAD_01778 4.7e-09 S YuzL-like protein
EFDNPGAD_01779 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
EFDNPGAD_01780 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
EFDNPGAD_01781 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
EFDNPGAD_01782 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
EFDNPGAD_01783 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
EFDNPGAD_01784 1.1e-39 yusG S Protein of unknown function (DUF2553)
EFDNPGAD_01785 3.3e-74 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
EFDNPGAD_01786 5.6e-55 traF CO Thioredoxin
EFDNPGAD_01787 2.4e-56 yusD S SCP-2 sterol transfer family
EFDNPGAD_01788 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EFDNPGAD_01789 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
EFDNPGAD_01790 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
EFDNPGAD_01791 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EFDNPGAD_01792 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
EFDNPGAD_01793 1.4e-245 sufD O assembly protein SufD
EFDNPGAD_01794 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EFDNPGAD_01795 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
EFDNPGAD_01796 3.5e-271 sufB O FeS cluster assembly
EFDNPGAD_01797 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EFDNPGAD_01798 1e-41
EFDNPGAD_01800 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
EFDNPGAD_01801 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
EFDNPGAD_01802 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
EFDNPGAD_01803 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
EFDNPGAD_01804 1.4e-156 yurN G Binding-protein-dependent transport system inner membrane component
EFDNPGAD_01805 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
EFDNPGAD_01806 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
EFDNPGAD_01807 1.1e-135 yurK K UTRA
EFDNPGAD_01808 1.2e-205 msmX P Belongs to the ABC transporter superfamily
EFDNPGAD_01809 2.4e-169 bsn L Ribonuclease
EFDNPGAD_01810 1.6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
EFDNPGAD_01811 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
EFDNPGAD_01813 1.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EFDNPGAD_01814 3.6e-111 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
EFDNPGAD_01815 3.4e-152 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
EFDNPGAD_01816 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
EFDNPGAD_01817 7.9e-99 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
EFDNPGAD_01818 7.3e-61 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
EFDNPGAD_01819 6.6e-284 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
EFDNPGAD_01820 1.3e-224 pbuX F xanthine
EFDNPGAD_01821 2.1e-236 pbuX F Permease family
EFDNPGAD_01822 1.2e-302 pucR QT COG2508 Regulator of polyketide synthase expression
EFDNPGAD_01823 1e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
EFDNPGAD_01824 3e-62 yunG
EFDNPGAD_01825 4.3e-171 yunF S Protein of unknown function DUF72
EFDNPGAD_01826 2e-141 yunE S membrane transporter protein
EFDNPGAD_01827 5.8e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
EFDNPGAD_01828 4.8e-48 yunC S Domain of unknown function (DUF1805)
EFDNPGAD_01829 8.4e-134 yunB S Sporulation protein YunB (Spo_YunB)
EFDNPGAD_01830 4.5e-196 lytH M Peptidase, M23
EFDNPGAD_01831 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EFDNPGAD_01832 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EFDNPGAD_01833 9.7e-48 yutD S protein conserved in bacteria
EFDNPGAD_01834 1e-75 yutE S Protein of unknown function DUF86
EFDNPGAD_01835 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EFDNPGAD_01836 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
EFDNPGAD_01837 2e-199 yutH S Spore coat protein
EFDNPGAD_01838 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
EFDNPGAD_01839 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EFDNPGAD_01840 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EFDNPGAD_01841 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
EFDNPGAD_01842 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
EFDNPGAD_01843 3.5e-57 yuzD S protein conserved in bacteria
EFDNPGAD_01844 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
EFDNPGAD_01845 3.2e-39 yuzB S Belongs to the UPF0349 family
EFDNPGAD_01846 2.4e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EFDNPGAD_01847 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EFDNPGAD_01848 3.7e-63 erpA S Belongs to the HesB IscA family
EFDNPGAD_01849 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EFDNPGAD_01850 9e-118 paiB K Putative FMN-binding domain
EFDNPGAD_01851 4.9e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EFDNPGAD_01853 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
EFDNPGAD_01854 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
EFDNPGAD_01855 8.4e-27 yuiB S Putative membrane protein
EFDNPGAD_01856 5.6e-118 yuiC S protein conserved in bacteria
EFDNPGAD_01857 1.2e-77 yuiD S protein conserved in bacteria
EFDNPGAD_01858 1.5e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EFDNPGAD_01859 3.9e-211 yuiF S antiporter
EFDNPGAD_01860 1.1e-93 bioY S Biotin biosynthesis protein
EFDNPGAD_01861 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
EFDNPGAD_01862 1.3e-167 besA S Putative esterase
EFDNPGAD_01863 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EFDNPGAD_01864 2.3e-226 entC 5.4.4.2 HQ Isochorismate synthase
EFDNPGAD_01865 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
EFDNPGAD_01866 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
EFDNPGAD_01867 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EFDNPGAD_01868 3.8e-36 mbtH S MbtH-like protein
EFDNPGAD_01869 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
EFDNPGAD_01870 1.2e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
EFDNPGAD_01871 6.5e-229 yukF QT Transcriptional regulator
EFDNPGAD_01872 2.8e-45 esxA S Belongs to the WXG100 family
EFDNPGAD_01873 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
EFDNPGAD_01874 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
EFDNPGAD_01875 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
EFDNPGAD_01876 0.0 esaA S type VII secretion protein EsaA
EFDNPGAD_01877 6.6e-65 yueC S Family of unknown function (DUF5383)
EFDNPGAD_01878 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EFDNPGAD_01879 4.8e-96 yueE S phosphohydrolase
EFDNPGAD_01880 2.9e-24 S Protein of unknown function (DUF2642)
EFDNPGAD_01881 6.1e-72 S Protein of unknown function (DUF2283)
EFDNPGAD_01882 2.7e-189 yueF S transporter activity
EFDNPGAD_01883 2.1e-32 yueG S Spore germination protein gerPA/gerPF
EFDNPGAD_01884 7.4e-39 yueH S YueH-like protein
EFDNPGAD_01885 1.6e-67 yueI S Protein of unknown function (DUF1694)
EFDNPGAD_01886 2.9e-104 pncA Q COG1335 Amidases related to nicotinamidase
EFDNPGAD_01887 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EFDNPGAD_01888 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
EFDNPGAD_01889 1.1e-22 yuzC
EFDNPGAD_01891 2.5e-162 comQ H Polyprenyl synthetase
EFDNPGAD_01893 0.0 comP 2.7.13.3 T Histidine kinase
EFDNPGAD_01894 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EFDNPGAD_01895 9.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
EFDNPGAD_01896 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
EFDNPGAD_01897 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EFDNPGAD_01898 4.8e-79 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EFDNPGAD_01899 3.8e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EFDNPGAD_01900 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EFDNPGAD_01901 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EFDNPGAD_01902 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
EFDNPGAD_01903 1.9e-14
EFDNPGAD_01904 1.3e-233 maeN C COG3493 Na citrate symporter
EFDNPGAD_01905 4.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
EFDNPGAD_01906 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
EFDNPGAD_01907 1.1e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
EFDNPGAD_01908 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
EFDNPGAD_01909 2.3e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
EFDNPGAD_01910 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
EFDNPGAD_01911 6.3e-78 yufK S Family of unknown function (DUF5366)
EFDNPGAD_01912 6.3e-75 yuxK S protein conserved in bacteria
EFDNPGAD_01913 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
EFDNPGAD_01914 3.5e-186 yuxJ EGP Major facilitator Superfamily
EFDNPGAD_01916 1.9e-115 kapD L the KinA pathway to sporulation
EFDNPGAD_01917 2e-70 kapB G Kinase associated protein B
EFDNPGAD_01918 4.6e-233 T PhoQ Sensor
EFDNPGAD_01919 1.8e-228 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
EFDNPGAD_01920 9.8e-42 yugE S Domain of unknown function (DUF1871)
EFDNPGAD_01921 1e-156 yugF I Hydrolase
EFDNPGAD_01922 1.6e-85 alaR K Transcriptional regulator
EFDNPGAD_01923 4.3e-200 yugH 2.6.1.1 E Aminotransferase
EFDNPGAD_01924 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
EFDNPGAD_01925 1.1e-34 yuzA S Domain of unknown function (DUF378)
EFDNPGAD_01926 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
EFDNPGAD_01927 2.8e-229 yugK C Dehydrogenase
EFDNPGAD_01928 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
EFDNPGAD_01930 1.3e-72 yugN S YugN-like family
EFDNPGAD_01931 1.7e-182 yugO P COG1226 Kef-type K transport systems
EFDNPGAD_01932 1.1e-53 mstX S Membrane-integrating protein Mistic
EFDNPGAD_01933 4.6e-39
EFDNPGAD_01934 1.4e-116 yugP S Zn-dependent protease
EFDNPGAD_01935 2.6e-236 yugS S COG1253 Hemolysins and related proteins containing CBS domains
EFDNPGAD_01936 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
EFDNPGAD_01937 2.1e-72 yugU S Uncharacterised protein family UPF0047
EFDNPGAD_01938 1e-35
EFDNPGAD_01939 2.6e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
EFDNPGAD_01940 3.2e-225 mcpA NT chemotaxis protein
EFDNPGAD_01941 1.5e-222 mcpA NT chemotaxis protein
EFDNPGAD_01942 2.2e-295 mcpA NT chemotaxis protein
EFDNPGAD_01943 5.1e-239 mcpA NT chemotaxis protein
EFDNPGAD_01944 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
EFDNPGAD_01945 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
EFDNPGAD_01946 1.3e-281 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
EFDNPGAD_01947 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
EFDNPGAD_01948 1.4e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
EFDNPGAD_01949 3.3e-183 ygjR S Oxidoreductase
EFDNPGAD_01950 6.3e-197 yubA S transporter activity
EFDNPGAD_01951 1.2e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EFDNPGAD_01953 2.6e-88 cdoA 1.13.11.20 S Cysteine dioxygenase type I
EFDNPGAD_01954 6.2e-277 yubD P Major Facilitator Superfamily
EFDNPGAD_01955 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EFDNPGAD_01956 1e-38 yiaA S yiaA/B two helix domain
EFDNPGAD_01957 5.4e-237 ktrB P Potassium
EFDNPGAD_01958 5e-122 ktrA P COG0569 K transport systems, NAD-binding component
EFDNPGAD_01959 2.2e-91 yuaB
EFDNPGAD_01960 1.1e-95 yuaC K Belongs to the GbsR family
EFDNPGAD_01961 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
EFDNPGAD_01962 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
EFDNPGAD_01963 7.9e-108 yuaD
EFDNPGAD_01964 3.9e-84 yuaE S DinB superfamily
EFDNPGAD_01965 1.4e-77 yuaF OU Membrane protein implicated in regulation of membrane protease activity
EFDNPGAD_01966 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
EFDNPGAD_01967 3.4e-94 M1-753 M FR47-like protein
EFDNPGAD_01968 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
EFDNPGAD_01969 4.3e-275 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
EFDNPGAD_01970 6e-193 yoxA 5.1.3.3 G Aldose 1-epimerase
EFDNPGAD_01971 2.3e-246 yoeA V MATE efflux family protein
EFDNPGAD_01972 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
EFDNPGAD_01974 2.2e-96 L Integrase
EFDNPGAD_01975 3e-34 yoeD G Helix-turn-helix domain
EFDNPGAD_01976 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
EFDNPGAD_01977 2.5e-158 gltR1 K Transcriptional regulator
EFDNPGAD_01978 5e-187 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
EFDNPGAD_01979 2.7e-293 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
EFDNPGAD_01980 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
EFDNPGAD_01981 7.8e-155 gltC K Transcriptional regulator
EFDNPGAD_01982 4.1e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EFDNPGAD_01983 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EFDNPGAD_01984 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
EFDNPGAD_01985 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EFDNPGAD_01986 3e-42 yoxC S Bacterial protein of unknown function (DUF948)
EFDNPGAD_01987 3.1e-144 yoxB
EFDNPGAD_01988 7.5e-97 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EFDNPGAD_01989 6.2e-235 yoaB EGP Major facilitator Superfamily
EFDNPGAD_01990 1e-284 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
EFDNPGAD_01991 1.7e-190 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EFDNPGAD_01992 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EFDNPGAD_01993 1.9e-33 yoaF
EFDNPGAD_01994 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
EFDNPGAD_01995 7e-14
EFDNPGAD_01996 1.5e-38 S Protein of unknown function (DUF4025)
EFDNPGAD_01997 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
EFDNPGAD_01998 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
EFDNPGAD_01999 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
EFDNPGAD_02000 2.3e-111 yoaK S Membrane
EFDNPGAD_02001 2.5e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
EFDNPGAD_02002 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
EFDNPGAD_02004 3.8e-234 oxdC 4.1.1.2 G Oxalate decarboxylase
EFDNPGAD_02006 1.9e-146 yoaP 3.1.3.18 K YoaP-like
EFDNPGAD_02007 1.2e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
EFDNPGAD_02008 5.9e-88
EFDNPGAD_02009 2.4e-172 yoaR V vancomycin resistance protein
EFDNPGAD_02010 4.3e-75 yoaS S Protein of unknown function (DUF2975)
EFDNPGAD_02011 4.2e-37 yozG K Transcriptional regulator
EFDNPGAD_02012 1.1e-149 yoaT S Protein of unknown function (DUF817)
EFDNPGAD_02013 8.6e-159 yoaU K LysR substrate binding domain
EFDNPGAD_02014 6e-160 yijE EG EamA-like transporter family
EFDNPGAD_02015 3.7e-78 yoaW
EFDNPGAD_02016 1.1e-118 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
EFDNPGAD_02017 2.3e-170 bla 3.5.2.6 V beta-lactamase
EFDNPGAD_02021 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
EFDNPGAD_02022 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
EFDNPGAD_02023 1.4e-37 S TM2 domain
EFDNPGAD_02024 5.7e-58 K Helix-turn-helix
EFDNPGAD_02026 1.6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
EFDNPGAD_02027 6.6e-127 yoqW S Belongs to the SOS response-associated peptidase family
EFDNPGAD_02028 1.8e-178 yobF
EFDNPGAD_02033 1.7e-207 S aspartate phosphatase
EFDNPGAD_02035 1.2e-123 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EFDNPGAD_02036 1.4e-59 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EFDNPGAD_02037 2.6e-38 S YolD-like protein
EFDNPGAD_02038 1.2e-49
EFDNPGAD_02039 0.0 K Psort location Cytoplasmic, score
EFDNPGAD_02040 2.7e-157 yobJ
EFDNPGAD_02041 3e-86 S SMI1-KNR4 cell-wall
EFDNPGAD_02042 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
EFDNPGAD_02043 7.9e-105 yokH G SMI1 / KNR4 family
EFDNPGAD_02044 9.5e-280 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
EFDNPGAD_02045 0.0 yobO M Pectate lyase superfamily protein
EFDNPGAD_02046 9.9e-55 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
EFDNPGAD_02047 1e-136 yobQ K helix_turn_helix, arabinose operon control protein
EFDNPGAD_02048 2.5e-143 yobR 2.3.1.1 J FR47-like protein
EFDNPGAD_02049 3e-99 yobS K Transcriptional regulator
EFDNPGAD_02050 4.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
EFDNPGAD_02051 1.5e-88 yobU K Bacterial transcription activator, effector binding domain
EFDNPGAD_02052 9e-178 yobV K WYL domain
EFDNPGAD_02053 2.5e-95 yobW
EFDNPGAD_02054 1e-51 czrA K transcriptional
EFDNPGAD_02055 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EFDNPGAD_02056 1.5e-92 yozB S membrane
EFDNPGAD_02057 2.2e-145
EFDNPGAD_02058 1.9e-94 yocC
EFDNPGAD_02059 6.9e-189 yocD 3.4.17.13 V peptidase S66
EFDNPGAD_02060 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
EFDNPGAD_02061 3.2e-198 desK 2.7.13.3 T Histidine kinase
EFDNPGAD_02062 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EFDNPGAD_02063 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
EFDNPGAD_02064 0.0 recQ 3.6.4.12 L DNA helicase
EFDNPGAD_02065 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EFDNPGAD_02066 3.3e-83 dksA T general stress protein
EFDNPGAD_02067 6.4e-54 yocL
EFDNPGAD_02068 6.6e-34
EFDNPGAD_02069 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
EFDNPGAD_02070 1.1e-40 yozN
EFDNPGAD_02071 1.9e-36 yocN
EFDNPGAD_02072 4.2e-56 yozO S Bacterial PH domain
EFDNPGAD_02073 2.7e-31 yozC
EFDNPGAD_02074 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
EFDNPGAD_02075 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
EFDNPGAD_02076 5.4e-166 sodA 1.15.1.1 P Superoxide dismutase
EFDNPGAD_02077 3.4e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EFDNPGAD_02078 5.1e-168 yocS S -transporter
EFDNPGAD_02079 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
EFDNPGAD_02080 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
EFDNPGAD_02081 0.0 yojO P Von Willebrand factor
EFDNPGAD_02082 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
EFDNPGAD_02083 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EFDNPGAD_02084 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
EFDNPGAD_02085 1.8e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
EFDNPGAD_02086 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EFDNPGAD_02088 4.2e-245 norM V Multidrug efflux pump
EFDNPGAD_02089 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EFDNPGAD_02090 2.1e-125 yojG S deacetylase
EFDNPGAD_02091 2.2e-60 yojF S Protein of unknown function (DUF1806)
EFDNPGAD_02092 1.5e-43
EFDNPGAD_02093 3.5e-163 rarD S -transporter
EFDNPGAD_02094 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
EFDNPGAD_02095 3.4e-09
EFDNPGAD_02096 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
EFDNPGAD_02097 3.8e-66 yodA S tautomerase
EFDNPGAD_02098 1.7e-57 yodB K transcriptional
EFDNPGAD_02099 4.8e-108 yodC C nitroreductase
EFDNPGAD_02100 3.8e-113 mhqD S Carboxylesterase
EFDNPGAD_02101 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
EFDNPGAD_02102 6.2e-28 S Protein of unknown function (DUF3311)
EFDNPGAD_02103 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EFDNPGAD_02104 1.9e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
EFDNPGAD_02105 1.7e-128 yodH Q Methyltransferase
EFDNPGAD_02106 5.2e-24 yodI
EFDNPGAD_02107 2.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
EFDNPGAD_02108 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
EFDNPGAD_02109 5.3e-09
EFDNPGAD_02110 3.6e-54 yodL S YodL-like
EFDNPGAD_02111 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
EFDNPGAD_02112 2.8e-24 yozD S YozD-like protein
EFDNPGAD_02114 1.4e-124 yodN
EFDNPGAD_02115 1.4e-36 yozE S Belongs to the UPF0346 family
EFDNPGAD_02116 2.9e-47 yokU S YokU-like protein, putative antitoxin
EFDNPGAD_02117 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
EFDNPGAD_02118 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
EFDNPGAD_02119 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
EFDNPGAD_02120 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EFDNPGAD_02121 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EFDNPGAD_02122 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EFDNPGAD_02124 2.9e-145 yiiD K acetyltransferase
EFDNPGAD_02125 1e-256 cgeD M maturation of the outermost layer of the spore
EFDNPGAD_02126 3.5e-38 cgeC
EFDNPGAD_02127 1.2e-65 cgeA
EFDNPGAD_02128 3.3e-188 cgeB S Spore maturation protein
EFDNPGAD_02129 3.6e-213 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
EFDNPGAD_02130 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
EFDNPGAD_02131 1.4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
EFDNPGAD_02132 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EFDNPGAD_02133 1.6e-70 ypoP K transcriptional
EFDNPGAD_02134 2.6e-223 mepA V MATE efflux family protein
EFDNPGAD_02135 5.5e-29 ypmT S Uncharacterized ympT
EFDNPGAD_02136 5e-99 ypmS S protein conserved in bacteria
EFDNPGAD_02137 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
EFDNPGAD_02138 3.2e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
EFDNPGAD_02139 3.1e-40 ypmP S Protein of unknown function (DUF2535)
EFDNPGAD_02140 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EFDNPGAD_02141 1.6e-185 pspF K Transcriptional regulator
EFDNPGAD_02142 4.2e-110 hlyIII S protein, Hemolysin III
EFDNPGAD_02143 7.4e-112 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EFDNPGAD_02144 7.9e-96 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EFDNPGAD_02145 4.3e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EFDNPGAD_02146 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
EFDNPGAD_02147 7.8e-114 ypjP S YpjP-like protein
EFDNPGAD_02148 1.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
EFDNPGAD_02149 1.7e-75 yphP S Belongs to the UPF0403 family
EFDNPGAD_02150 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
EFDNPGAD_02151 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
EFDNPGAD_02152 3.1e-110 ypgQ S phosphohydrolase
EFDNPGAD_02153 2.3e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
EFDNPGAD_02154 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EFDNPGAD_02155 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
EFDNPGAD_02156 7.9e-31 cspD K Cold-shock protein
EFDNPGAD_02157 3.8e-16 degR
EFDNPGAD_02158 8.1e-31 S Protein of unknown function (DUF2564)
EFDNPGAD_02159 2.6e-27 ypeQ S Zinc-finger
EFDNPGAD_02160 8.9e-127 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
EFDNPGAD_02161 1.1e-121 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EFDNPGAD_02162 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
EFDNPGAD_02164 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
EFDNPGAD_02165 2e-07
EFDNPGAD_02166 1e-38 ypbS S Protein of unknown function (DUF2533)
EFDNPGAD_02167 0.0 ypbR S Dynamin family
EFDNPGAD_02168 5.1e-87 ypbQ S protein conserved in bacteria
EFDNPGAD_02169 4.4e-208 bcsA Q Naringenin-chalcone synthase
EFDNPGAD_02170 1.6e-228 pbuX F xanthine
EFDNPGAD_02171 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EFDNPGAD_02172 4.2e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EFDNPGAD_02173 5e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
EFDNPGAD_02174 7e-104 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
EFDNPGAD_02175 2.9e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
EFDNPGAD_02176 3.9e-187 ptxS K transcriptional
EFDNPGAD_02177 1.7e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EFDNPGAD_02178 7.1e-133 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EFDNPGAD_02179 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
EFDNPGAD_02181 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
EFDNPGAD_02182 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EFDNPGAD_02183 3.3e-92 ypsA S Belongs to the UPF0398 family
EFDNPGAD_02184 1.3e-237 yprB L RNase_H superfamily
EFDNPGAD_02185 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
EFDNPGAD_02186 1.9e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
EFDNPGAD_02187 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
EFDNPGAD_02188 1.2e-48 yppG S YppG-like protein
EFDNPGAD_02190 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
EFDNPGAD_02193 2.6e-188 yppC S Protein of unknown function (DUF2515)
EFDNPGAD_02194 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EFDNPGAD_02195 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
EFDNPGAD_02196 4.7e-93 ypoC
EFDNPGAD_02197 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EFDNPGAD_02198 5.7e-129 dnaD L DNA replication protein DnaD
EFDNPGAD_02199 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
EFDNPGAD_02200 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
EFDNPGAD_02201 3.4e-80 ypmB S protein conserved in bacteria
EFDNPGAD_02202 6.7e-23 ypmA S Protein of unknown function (DUF4264)
EFDNPGAD_02203 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
EFDNPGAD_02204 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EFDNPGAD_02205 1.2e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EFDNPGAD_02206 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
EFDNPGAD_02207 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EFDNPGAD_02208 4.4e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EFDNPGAD_02209 3.7e-210 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
EFDNPGAD_02210 6.9e-130 bshB1 S proteins, LmbE homologs
EFDNPGAD_02211 6.5e-72 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
EFDNPGAD_02212 6.3e-148 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EFDNPGAD_02213 3.1e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
EFDNPGAD_02214 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
EFDNPGAD_02215 6.1e-143 ypjB S sporulation protein
EFDNPGAD_02216 4.4e-98 ypjA S membrane
EFDNPGAD_02217 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
EFDNPGAD_02218 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
EFDNPGAD_02219 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
EFDNPGAD_02220 8.5e-78 ypiF S Protein of unknown function (DUF2487)
EFDNPGAD_02221 2.8e-99 ypiB S Belongs to the UPF0302 family
EFDNPGAD_02222 4.1e-234 S COG0457 FOG TPR repeat
EFDNPGAD_02223 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EFDNPGAD_02224 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
EFDNPGAD_02225 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EFDNPGAD_02226 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
EFDNPGAD_02227 4e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EFDNPGAD_02228 6.5e-119 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
EFDNPGAD_02229 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
EFDNPGAD_02230 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EFDNPGAD_02231 6.6e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EFDNPGAD_02232 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
EFDNPGAD_02233 8.1e-207 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EFDNPGAD_02234 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EFDNPGAD_02235 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
EFDNPGAD_02236 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
EFDNPGAD_02237 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EFDNPGAD_02238 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
EFDNPGAD_02239 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
EFDNPGAD_02240 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
EFDNPGAD_02241 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
EFDNPGAD_02242 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EFDNPGAD_02243 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EFDNPGAD_02244 5.4e-138 yphF
EFDNPGAD_02245 1.6e-18 yphE S Protein of unknown function (DUF2768)
EFDNPGAD_02246 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
EFDNPGAD_02247 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
EFDNPGAD_02248 1.6e-28 ypzH
EFDNPGAD_02249 2.5e-161 seaA S YIEGIA protein
EFDNPGAD_02250 1.3e-102 yphA
EFDNPGAD_02251 1e-07 S YpzI-like protein
EFDNPGAD_02252 4.1e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EFDNPGAD_02253 4.3e-206 rpsA 1.17.7.4 J Ribosomal protein S1
EFDNPGAD_02254 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
EFDNPGAD_02255 1.8e-23 S Family of unknown function (DUF5359)
EFDNPGAD_02256 9.2e-113 ypfA M Flagellar protein YcgR
EFDNPGAD_02257 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
EFDNPGAD_02258 4.7e-155 sleB 3.5.1.28 M Spore cortex-lytic enzyme
EFDNPGAD_02259 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
EFDNPGAD_02260 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
EFDNPGAD_02261 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
EFDNPGAD_02262 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EFDNPGAD_02263 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
EFDNPGAD_02264 2.8e-81 ypbF S Protein of unknown function (DUF2663)
EFDNPGAD_02265 4.6e-81 ypbE M Lysin motif
EFDNPGAD_02266 2.2e-100 ypbD S metal-dependent membrane protease
EFDNPGAD_02267 3.2e-286 recQ 3.6.4.12 L DNA helicase
EFDNPGAD_02268 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
EFDNPGAD_02269 4.7e-41 fer C Ferredoxin
EFDNPGAD_02270 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EFDNPGAD_02271 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EFDNPGAD_02272 9e-136 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
EFDNPGAD_02273 6.8e-201 rsiX
EFDNPGAD_02274 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
EFDNPGAD_02275 0.0 resE 2.7.13.3 T Histidine kinase
EFDNPGAD_02276 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFDNPGAD_02277 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
EFDNPGAD_02278 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
EFDNPGAD_02279 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
EFDNPGAD_02280 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EFDNPGAD_02281 1.9e-87 spmB S Spore maturation protein
EFDNPGAD_02282 3.5e-103 spmA S Spore maturation protein
EFDNPGAD_02283 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
EFDNPGAD_02284 4e-98 ypuI S Protein of unknown function (DUF3907)
EFDNPGAD_02285 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EFDNPGAD_02286 4.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EFDNPGAD_02287 4.5e-94 ypuF S Domain of unknown function (DUF309)
EFDNPGAD_02288 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EFDNPGAD_02289 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
EFDNPGAD_02290 9.8e-230 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EFDNPGAD_02291 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
EFDNPGAD_02292 1.3e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EFDNPGAD_02293 6e-55 ypuD
EFDNPGAD_02294 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
EFDNPGAD_02295 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
EFDNPGAD_02296 1.5e-17 S SNARE associated Golgi protein
EFDNPGAD_02299 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EFDNPGAD_02300 1.3e-149 ypuA S Secreted protein
EFDNPGAD_02301 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EFDNPGAD_02302 1.4e-273 spoVAF EG Stage V sporulation protein AF
EFDNPGAD_02303 1.4e-110 spoVAEA S stage V sporulation protein
EFDNPGAD_02304 2.2e-57 spoVAEB S stage V sporulation protein
EFDNPGAD_02305 9e-192 spoVAD I Stage V sporulation protein AD
EFDNPGAD_02306 2.3e-78 spoVAC S stage V sporulation protein AC
EFDNPGAD_02307 1e-67 spoVAB S Stage V sporulation protein AB
EFDNPGAD_02308 7.4e-112 spoVAA S Stage V sporulation protein AA
EFDNPGAD_02309 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EFDNPGAD_02310 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
EFDNPGAD_02311 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
EFDNPGAD_02312 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
EFDNPGAD_02313 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EFDNPGAD_02314 1.2e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
EFDNPGAD_02315 2.6e-166 xerD L recombinase XerD
EFDNPGAD_02316 3.7e-37 S Protein of unknown function (DUF4227)
EFDNPGAD_02317 2.4e-80 fur P Belongs to the Fur family
EFDNPGAD_02318 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
EFDNPGAD_02319 2e-32 yqkK
EFDNPGAD_02320 5.5e-242 mleA 1.1.1.38 C malic enzyme
EFDNPGAD_02321 3.1e-235 mleN C Na H antiporter
EFDNPGAD_02322 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
EFDNPGAD_02323 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
EFDNPGAD_02324 4.5e-58 ansR K Transcriptional regulator
EFDNPGAD_02325 3e-223 yqxK 3.6.4.12 L DNA helicase
EFDNPGAD_02326 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
EFDNPGAD_02328 4.4e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
EFDNPGAD_02329 4e-14 yqkE S Protein of unknown function (DUF3886)
EFDNPGAD_02330 2.4e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
EFDNPGAD_02331 9.4e-39 yqkC S Protein of unknown function (DUF2552)
EFDNPGAD_02332 2.8e-54 yqkB S Belongs to the HesB IscA family
EFDNPGAD_02333 4.7e-196 yqkA K GrpB protein
EFDNPGAD_02334 8e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
EFDNPGAD_02335 3.6e-87 yqjY K acetyltransferase
EFDNPGAD_02336 2.2e-49 S YolD-like protein
EFDNPGAD_02337 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EFDNPGAD_02339 5.2e-226 yqjV G Major Facilitator Superfamily
EFDNPGAD_02341 7.2e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EFDNPGAD_02342 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
EFDNPGAD_02343 2.4e-264 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
EFDNPGAD_02344 3.5e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
EFDNPGAD_02345 3.4e-180 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
EFDNPGAD_02346 8.6e-148 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EFDNPGAD_02347 0.0 rocB E arginine degradation protein
EFDNPGAD_02348 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
EFDNPGAD_02349 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EFDNPGAD_02350 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EFDNPGAD_02351 1.6e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EFDNPGAD_02352 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EFDNPGAD_02353 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EFDNPGAD_02354 4.5e-24 yqzJ
EFDNPGAD_02355 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EFDNPGAD_02356 3.6e-142 yqjF S Uncharacterized conserved protein (COG2071)
EFDNPGAD_02357 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
EFDNPGAD_02358 4.4e-291 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EFDNPGAD_02359 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
EFDNPGAD_02361 1.4e-98 yqjB S protein conserved in bacteria
EFDNPGAD_02362 1.1e-175 yqjA S Putative aromatic acid exporter C-terminal domain
EFDNPGAD_02363 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
EFDNPGAD_02364 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
EFDNPGAD_02365 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
EFDNPGAD_02366 9.3e-77 yqiW S Belongs to the UPF0403 family
EFDNPGAD_02367 8.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EFDNPGAD_02368 7.9e-208 norA EGP Major facilitator Superfamily
EFDNPGAD_02369 2.6e-152 bmrR K helix_turn_helix, mercury resistance
EFDNPGAD_02370 3.5e-233 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EFDNPGAD_02371 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EFDNPGAD_02372 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EFDNPGAD_02373 3.4e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EFDNPGAD_02374 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
EFDNPGAD_02375 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
EFDNPGAD_02376 7.1e-156 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
EFDNPGAD_02377 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
EFDNPGAD_02378 4e-34 yqzF S Protein of unknown function (DUF2627)
EFDNPGAD_02379 7.1e-164 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EFDNPGAD_02380 5.7e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
EFDNPGAD_02381 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
EFDNPGAD_02382 1.8e-212 mmgC I acyl-CoA dehydrogenase
EFDNPGAD_02383 4.7e-157 hbdA 1.1.1.157 I Dehydrogenase
EFDNPGAD_02384 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
EFDNPGAD_02385 1.8e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
EFDNPGAD_02386 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
EFDNPGAD_02387 5.9e-27
EFDNPGAD_02388 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
EFDNPGAD_02390 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
EFDNPGAD_02391 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
EFDNPGAD_02392 0.0 recN L May be involved in recombinational repair of damaged DNA
EFDNPGAD_02393 1.7e-78 argR K Regulates arginine biosynthesis genes
EFDNPGAD_02394 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
EFDNPGAD_02395 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EFDNPGAD_02396 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EFDNPGAD_02397 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EFDNPGAD_02398 2.2e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EFDNPGAD_02399 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EFDNPGAD_02400 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EFDNPGAD_02401 2.1e-67 yqhY S protein conserved in bacteria
EFDNPGAD_02402 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
EFDNPGAD_02403 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EFDNPGAD_02404 9.9e-91 spoIIIAH S SpoIIIAH-like protein
EFDNPGAD_02405 6.9e-103 spoIIIAG S stage III sporulation protein AG
EFDNPGAD_02406 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
EFDNPGAD_02407 1.3e-197 spoIIIAE S stage III sporulation protein AE
EFDNPGAD_02408 2.3e-58 spoIIIAD S Stage III sporulation protein AD
EFDNPGAD_02409 7.6e-29 spoIIIAC S stage III sporulation protein AC
EFDNPGAD_02410 2.9e-85 spoIIIAB S Stage III sporulation protein
EFDNPGAD_02411 1.2e-171 spoIIIAA S stage III sporulation protein AA
EFDNPGAD_02412 7.9e-37 yqhV S Protein of unknown function (DUF2619)
EFDNPGAD_02413 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EFDNPGAD_02414 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
EFDNPGAD_02415 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
EFDNPGAD_02416 2.3e-93 yqhR S Conserved membrane protein YqhR
EFDNPGAD_02417 2.1e-174 yqhQ S Protein of unknown function (DUF1385)
EFDNPGAD_02418 2.2e-61 yqhP
EFDNPGAD_02419 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
EFDNPGAD_02420 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
EFDNPGAD_02421 5.2e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
EFDNPGAD_02422 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
EFDNPGAD_02423 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EFDNPGAD_02424 3.4e-255 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EFDNPGAD_02425 9.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
EFDNPGAD_02426 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
EFDNPGAD_02427 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
EFDNPGAD_02428 1.2e-24 sinI S Anti-repressor SinI
EFDNPGAD_02429 1e-54 sinR K transcriptional
EFDNPGAD_02430 2.3e-142 tasA S Cell division protein FtsN
EFDNPGAD_02431 6.7e-59 sipW 3.4.21.89 U Signal peptidase
EFDNPGAD_02432 2.1e-116 yqxM
EFDNPGAD_02433 7.3e-54 yqzG S Protein of unknown function (DUF3889)
EFDNPGAD_02434 1.4e-26 yqzE S YqzE-like protein
EFDNPGAD_02435 3.7e-42 S ComG operon protein 7
EFDNPGAD_02436 5.5e-49 comGF U Putative Competence protein ComGF
EFDNPGAD_02437 1.1e-59 comGE
EFDNPGAD_02438 4.4e-71 gspH NU protein transport across the cell outer membrane
EFDNPGAD_02439 1.4e-47 comGC U Required for transformation and DNA binding
EFDNPGAD_02440 1.6e-175 comGB NU COG1459 Type II secretory pathway, component PulF
EFDNPGAD_02441 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EFDNPGAD_02443 7.2e-175 corA P Mg2 transporter protein
EFDNPGAD_02444 5.2e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
EFDNPGAD_02445 1.7e-151 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EFDNPGAD_02447 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
EFDNPGAD_02448 1.8e-37 yqgY S Protein of unknown function (DUF2626)
EFDNPGAD_02449 1.9e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
EFDNPGAD_02450 8.9e-23 yqgW S Protein of unknown function (DUF2759)
EFDNPGAD_02451 6.9e-50 yqgV S Thiamine-binding protein
EFDNPGAD_02452 2.7e-199 yqgU
EFDNPGAD_02453 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
EFDNPGAD_02454 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
EFDNPGAD_02455 5.2e-181 glcK 2.7.1.2 G Glucokinase
EFDNPGAD_02456 3.1e-33 yqgQ S Protein conserved in bacteria
EFDNPGAD_02457 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
EFDNPGAD_02458 2.5e-09 yqgO
EFDNPGAD_02459 2.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EFDNPGAD_02460 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EFDNPGAD_02461 3.2e-203 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
EFDNPGAD_02463 9.2e-51 yqzD
EFDNPGAD_02464 1.9e-75 yqzC S YceG-like family
EFDNPGAD_02465 9.8e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EFDNPGAD_02466 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EFDNPGAD_02467 4.4e-158 pstA P Phosphate transport system permease
EFDNPGAD_02468 1.3e-160 pstC P probably responsible for the translocation of the substrate across the membrane
EFDNPGAD_02469 5.3e-151 pstS P Phosphate
EFDNPGAD_02470 0.0 pbpA 3.4.16.4 M penicillin-binding protein
EFDNPGAD_02471 2.5e-231 yqgE EGP Major facilitator superfamily
EFDNPGAD_02472 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
EFDNPGAD_02473 4e-73 yqgC S protein conserved in bacteria
EFDNPGAD_02474 8.5e-134 yqgB S Protein of unknown function (DUF1189)
EFDNPGAD_02475 2.2e-75 yqgA
EFDNPGAD_02476 5.2e-47 yqfZ M LysM domain
EFDNPGAD_02477 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EFDNPGAD_02478 4.3e-62 yqfX S membrane
EFDNPGAD_02479 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
EFDNPGAD_02480 1.9e-77 zur P Belongs to the Fur family
EFDNPGAD_02481 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
EFDNPGAD_02482 2.1e-36 yqfT S Protein of unknown function (DUF2624)
EFDNPGAD_02483 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EFDNPGAD_02484 1.7e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EFDNPGAD_02485 2.9e-14 yqfQ S YqfQ-like protein
EFDNPGAD_02486 2.6e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EFDNPGAD_02487 5.1e-212 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EFDNPGAD_02488 6.1e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
EFDNPGAD_02489 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
EFDNPGAD_02490 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EFDNPGAD_02491 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EFDNPGAD_02492 4.5e-88 yaiI S Belongs to the UPF0178 family
EFDNPGAD_02493 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
EFDNPGAD_02494 4.5e-112 ccpN K CBS domain
EFDNPGAD_02495 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
EFDNPGAD_02496 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
EFDNPGAD_02497 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
EFDNPGAD_02498 8.4e-19 S YqzL-like protein
EFDNPGAD_02499 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EFDNPGAD_02500 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
EFDNPGAD_02501 1.6e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
EFDNPGAD_02502 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EFDNPGAD_02503 0.0 yqfF S membrane-associated HD superfamily hydrolase
EFDNPGAD_02505 1.1e-175 phoH T Phosphate starvation-inducible protein PhoH
EFDNPGAD_02506 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
EFDNPGAD_02507 2.7e-45 yqfC S sporulation protein YqfC
EFDNPGAD_02508 6e-25 yqfB
EFDNPGAD_02509 4.3e-122 yqfA S UPF0365 protein
EFDNPGAD_02510 5.4e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
EFDNPGAD_02511 2.5e-61 yqeY S Yqey-like protein
EFDNPGAD_02512 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
EFDNPGAD_02513 1.6e-158 yqeW P COG1283 Na phosphate symporter
EFDNPGAD_02514 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
EFDNPGAD_02515 1.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EFDNPGAD_02516 5.4e-175 prmA J Methylates ribosomal protein L11
EFDNPGAD_02517 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EFDNPGAD_02518 0.0 dnaK O Heat shock 70 kDa protein
EFDNPGAD_02519 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EFDNPGAD_02520 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EFDNPGAD_02521 4.8e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
EFDNPGAD_02522 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EFDNPGAD_02523 1e-54 yqxA S Protein of unknown function (DUF3679)
EFDNPGAD_02524 6.9e-223 spoIIP M stage II sporulation protein P
EFDNPGAD_02525 1.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EFDNPGAD_02526 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
EFDNPGAD_02527 1.1e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
EFDNPGAD_02528 4.1e-15 S YqzM-like protein
EFDNPGAD_02529 0.0 comEC S Competence protein ComEC
EFDNPGAD_02530 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
EFDNPGAD_02531 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
EFDNPGAD_02532 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EFDNPGAD_02533 2.9e-139 yqeM Q Methyltransferase
EFDNPGAD_02534 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EFDNPGAD_02535 7.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
EFDNPGAD_02536 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EFDNPGAD_02537 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
EFDNPGAD_02538 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EFDNPGAD_02539 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
EFDNPGAD_02540 5.3e-95 yqeG S hydrolase of the HAD superfamily
EFDNPGAD_02542 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
EFDNPGAD_02543 2.1e-137 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EFDNPGAD_02544 4.7e-106 yqeD S SNARE associated Golgi protein
EFDNPGAD_02545 1.2e-171 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
EFDNPGAD_02546 2.3e-133 yqeB
EFDNPGAD_02547 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
EFDNPGAD_02548 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EFDNPGAD_02549 1.4e-281 cisA2 L Recombinase
EFDNPGAD_02550 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
EFDNPGAD_02551 6e-183 arsB 1.20.4.1 P Arsenic resistance protein
EFDNPGAD_02552 2.8e-73 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EFDNPGAD_02553 1.6e-54 arsR K ArsR family transcriptional regulator
EFDNPGAD_02554 1.1e-152 yqcI S YqcI/YcgG family
EFDNPGAD_02555 1.6e-96 S Tetratricopeptide repeat
EFDNPGAD_02558 3.8e-277 A Pre-toxin TG
EFDNPGAD_02559 1.1e-104 S Suppressor of fused protein (SUFU)
EFDNPGAD_02561 5e-60
EFDNPGAD_02563 1.1e-144 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
EFDNPGAD_02564 2.6e-68 S Bacteriophage holin family
EFDNPGAD_02565 4.8e-165 xepA
EFDNPGAD_02566 1.3e-23
EFDNPGAD_02567 4.1e-56 xkdW S XkdW protein
EFDNPGAD_02568 2e-221
EFDNPGAD_02569 9.6e-40
EFDNPGAD_02570 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
EFDNPGAD_02571 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
EFDNPGAD_02572 9.6e-71 xkdS S Protein of unknown function (DUF2634)
EFDNPGAD_02573 1.8e-38 xkdR S Protein of unknown function (DUF2577)
EFDNPGAD_02574 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
EFDNPGAD_02575 9e-114 xkdP S Lysin motif
EFDNPGAD_02576 0.0 xkdO L Transglycosylase SLT domain
EFDNPGAD_02577 1.8e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
EFDNPGAD_02579 3.6e-76 xkdM S Phage tail tube protein
EFDNPGAD_02580 5.5e-256 xkdK S Phage tail sheath C-terminal domain
EFDNPGAD_02581 3.2e-26
EFDNPGAD_02582 1.4e-77
EFDNPGAD_02583 4.3e-94 S Bacteriophage HK97-gp10, putative tail-component
EFDNPGAD_02584 6.7e-65 yqbH S Domain of unknown function (DUF3599)
EFDNPGAD_02585 2.1e-67 S Protein of unknown function (DUF3199)
EFDNPGAD_02586 3.6e-51 S YqbF, hypothetical protein domain
EFDNPGAD_02587 1.9e-167 xkdG S Phage capsid family
EFDNPGAD_02588 5.1e-128 yqbD 2.1.1.72 L Putative phage serine protease XkdF
EFDNPGAD_02589 2e-115
EFDNPGAD_02590 5.7e-169 S Phage Mu protein F like protein
EFDNPGAD_02591 5.9e-296 yqbA S portal protein
EFDNPGAD_02592 2.4e-253 S phage terminase, large subunit
EFDNPGAD_02593 6.3e-107 yqaS L DNA packaging
EFDNPGAD_02595 6.5e-81 L Transposase
EFDNPGAD_02596 1.6e-166
EFDNPGAD_02597 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
EFDNPGAD_02598 7.2e-74 rusA L Endodeoxyribonuclease RusA
EFDNPGAD_02600 5.9e-168 xkdC L IstB-like ATP binding protein
EFDNPGAD_02601 1e-122 3.1.3.16 L DnaD domain protein
EFDNPGAD_02602 2.5e-155 recT L RecT family
EFDNPGAD_02603 1.5e-180 yqaJ L YqaJ-like viral recombinase domain
EFDNPGAD_02607 1.2e-103
EFDNPGAD_02609 6.5e-37 K Helix-turn-helix XRE-family like proteins
EFDNPGAD_02610 1.1e-56 K sequence-specific DNA binding
EFDNPGAD_02612 1e-101 adk 2.7.4.3 F adenylate kinase activity
EFDNPGAD_02613 1.4e-100 yqaB E IrrE N-terminal-like domain
EFDNPGAD_02614 1.2e-280 cisA2 L Recombinase
EFDNPGAD_02615 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
EFDNPGAD_02616 6e-183 arsB 1.20.4.1 P Arsenic resistance protein
EFDNPGAD_02617 2.8e-73 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EFDNPGAD_02618 1.6e-54 arsR K ArsR family transcriptional regulator
EFDNPGAD_02619 1.1e-152 yqcI S YqcI/YcgG family
EFDNPGAD_02620 1.6e-96 S Tetratricopeptide repeat
EFDNPGAD_02623 3.8e-277 A Pre-toxin TG
EFDNPGAD_02624 1.1e-104 S Suppressor of fused protein (SUFU)
EFDNPGAD_02626 5e-60
EFDNPGAD_02628 1.1e-144 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
EFDNPGAD_02629 2.6e-68 S Bacteriophage holin family
EFDNPGAD_02630 4.8e-165 xepA
EFDNPGAD_02631 1.3e-23
EFDNPGAD_02632 4.1e-56 xkdW S XkdW protein
EFDNPGAD_02633 2e-221
EFDNPGAD_02634 9.6e-40
EFDNPGAD_02635 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
EFDNPGAD_02636 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
EFDNPGAD_02637 9.6e-71 xkdS S Protein of unknown function (DUF2634)
EFDNPGAD_02638 1.8e-38 xkdR S Protein of unknown function (DUF2577)
EFDNPGAD_02639 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
EFDNPGAD_02640 9e-114 xkdP S Lysin motif
EFDNPGAD_02641 0.0 xkdO L Transglycosylase SLT domain
EFDNPGAD_02642 1.8e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
EFDNPGAD_02644 3.6e-76 xkdM S Phage tail tube protein
EFDNPGAD_02645 5.5e-256 xkdK S Phage tail sheath C-terminal domain
EFDNPGAD_02646 3.2e-26
EFDNPGAD_02647 1.4e-77
EFDNPGAD_02648 4.3e-94 S Bacteriophage HK97-gp10, putative tail-component
EFDNPGAD_02649 6.7e-65 yqbH S Domain of unknown function (DUF3599)
EFDNPGAD_02650 2.1e-67 S Protein of unknown function (DUF3199)
EFDNPGAD_02651 3.6e-51 S YqbF, hypothetical protein domain
EFDNPGAD_02652 1.9e-167 xkdG S Phage capsid family
EFDNPGAD_02653 5.1e-128 yqbD 2.1.1.72 L Putative phage serine protease XkdF
EFDNPGAD_02654 2e-115
EFDNPGAD_02655 5.7e-169 S Phage Mu protein F like protein
EFDNPGAD_02656 5.9e-296 yqbA S portal protein
EFDNPGAD_02657 2.4e-253 S phage terminase, large subunit
EFDNPGAD_02658 6.3e-107 yqaS L DNA packaging
EFDNPGAD_02660 6.5e-81 L Transposase
EFDNPGAD_02661 1.6e-166
EFDNPGAD_02662 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
EFDNPGAD_02663 7.2e-74 rusA L Endodeoxyribonuclease RusA
EFDNPGAD_02665 5.9e-168 xkdC L IstB-like ATP binding protein
EFDNPGAD_02666 1e-122 3.1.3.16 L DnaD domain protein
EFDNPGAD_02667 2.5e-155 recT L RecT family
EFDNPGAD_02668 1.5e-180 yqaJ L YqaJ-like viral recombinase domain
EFDNPGAD_02672 1.2e-103
EFDNPGAD_02674 6.5e-37 K Helix-turn-helix XRE-family like proteins
EFDNPGAD_02675 1.1e-56 K sequence-specific DNA binding
EFDNPGAD_02677 1e-101 adk 2.7.4.3 F adenylate kinase activity
EFDNPGAD_02678 1.4e-100 yqaB E IrrE N-terminal-like domain
EFDNPGAD_02683 2e-08
EFDNPGAD_02690 1.3e-09
EFDNPGAD_02691 7.8e-08
EFDNPGAD_02700 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EFDNPGAD_02701 3.6e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EFDNPGAD_02702 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
EFDNPGAD_02703 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
EFDNPGAD_02704 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
EFDNPGAD_02705 9.9e-77 tspO T membrane
EFDNPGAD_02706 1.8e-206 cotI S Spore coat protein
EFDNPGAD_02707 1.8e-217 cotSA M Glycosyl transferases group 1
EFDNPGAD_02708 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
EFDNPGAD_02710 3.6e-235 ytcC M Glycosyltransferase Family 4
EFDNPGAD_02711 3.9e-181 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
EFDNPGAD_02712 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EFDNPGAD_02713 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
EFDNPGAD_02714 2.6e-132 dksA T COG1734 DnaK suppressor protein
EFDNPGAD_02715 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
EFDNPGAD_02716 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EFDNPGAD_02717 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
EFDNPGAD_02718 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EFDNPGAD_02719 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
EFDNPGAD_02720 1.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
EFDNPGAD_02721 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
EFDNPGAD_02722 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
EFDNPGAD_02723 3.2e-234 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
EFDNPGAD_02724 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
EFDNPGAD_02725 1.1e-24 S Domain of Unknown Function (DUF1540)
EFDNPGAD_02726 7.3e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
EFDNPGAD_02727 4.7e-249 cydA 1.10.3.14 C oxidase, subunit
EFDNPGAD_02728 3.6e-41 rpmE2 J Ribosomal protein L31
EFDNPGAD_02729 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
EFDNPGAD_02730 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EFDNPGAD_02731 3.6e-73 ytkA S YtkA-like
EFDNPGAD_02733 2.1e-76 dps P Belongs to the Dps family
EFDNPGAD_02734 5.4e-63 ytkC S Bacteriophage holin family
EFDNPGAD_02735 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
EFDNPGAD_02736 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
EFDNPGAD_02737 1.4e-144 ytlC P ABC transporter
EFDNPGAD_02738 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
EFDNPGAD_02739 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
EFDNPGAD_02740 1.2e-38 ytmB S Protein of unknown function (DUF2584)
EFDNPGAD_02741 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EFDNPGAD_02742 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EFDNPGAD_02743 0.0 asnB 6.3.5.4 E Asparagine synthase
EFDNPGAD_02744 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
EFDNPGAD_02745 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EFDNPGAD_02746 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
EFDNPGAD_02747 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
EFDNPGAD_02748 3.3e-106 ytqB J Putative rRNA methylase
EFDNPGAD_02749 2.1e-190 yhcC S Fe-S oxidoreductase
EFDNPGAD_02750 6.7e-41 ytzC S Protein of unknown function (DUF2524)
EFDNPGAD_02752 5.1e-66 ytrA K GntR family transcriptional regulator
EFDNPGAD_02753 1.1e-161 ytrB P abc transporter atp-binding protein
EFDNPGAD_02754 6.1e-169 P ABC-2 family transporter protein
EFDNPGAD_02755 5.9e-148
EFDNPGAD_02756 3.1e-127 ytrE V ABC transporter, ATP-binding protein
EFDNPGAD_02757 8.5e-235 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
EFDNPGAD_02758 5.2e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFDNPGAD_02759 5.6e-186 T PhoQ Sensor
EFDNPGAD_02760 1.1e-138 bceA V ABC transporter, ATP-binding protein
EFDNPGAD_02761 0.0 bceB V ABC transporter (permease)
EFDNPGAD_02762 1.8e-43 yttA 2.7.13.3 S Pfam Transposase IS66
EFDNPGAD_02763 2.1e-211 yttB EGP Major facilitator Superfamily
EFDNPGAD_02764 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
EFDNPGAD_02765 7.7e-55 ytvB S Protein of unknown function (DUF4257)
EFDNPGAD_02766 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
EFDNPGAD_02767 2.1e-51 ytwF P Sulfurtransferase
EFDNPGAD_02768 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
EFDNPGAD_02769 1.5e-144 amyC P ABC transporter (permease)
EFDNPGAD_02770 3.7e-168 amyD P ABC transporter
EFDNPGAD_02771 2.3e-248 msmE G Bacterial extracellular solute-binding protein
EFDNPGAD_02772 2.3e-190 msmR K Transcriptional regulator
EFDNPGAD_02773 1.3e-173 ytaP S Acetyl xylan esterase (AXE1)
EFDNPGAD_02774 1.6e-142 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
EFDNPGAD_02775 2.4e-261 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
EFDNPGAD_02776 1.4e-220 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EFDNPGAD_02777 3.7e-128 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EFDNPGAD_02778 2.2e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EFDNPGAD_02779 1.9e-225 bioI 1.14.14.46 C Cytochrome P450
EFDNPGAD_02780 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
EFDNPGAD_02781 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
EFDNPGAD_02782 1.2e-290 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
EFDNPGAD_02783 0.0 ytdP K Transcriptional regulator
EFDNPGAD_02784 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
EFDNPGAD_02785 4.7e-226 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
EFDNPGAD_02786 4.6e-73 yteS G transport
EFDNPGAD_02787 9.2e-258 yteT S Oxidoreductase family, C-terminal alpha/beta domain
EFDNPGAD_02788 4.8e-117 yteU S Integral membrane protein
EFDNPGAD_02789 3.1e-26 yteV S Sporulation protein Cse60
EFDNPGAD_02790 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
EFDNPGAD_02791 8.2e-232 ytfP S HI0933-like protein
EFDNPGAD_02792 1.9e-281 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EFDNPGAD_02793 2.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EFDNPGAD_02794 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
EFDNPGAD_02795 4.3e-132 ythP V ABC transporter
EFDNPGAD_02796 3.9e-207 ythQ U Bacterial ABC transporter protein EcsB
EFDNPGAD_02797 7.2e-226 pbuO S permease
EFDNPGAD_02798 7.1e-272 pepV 3.5.1.18 E Dipeptidase
EFDNPGAD_02799 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EFDNPGAD_02800 4.3e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EFDNPGAD_02801 1.3e-165 ytlQ
EFDNPGAD_02802 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
EFDNPGAD_02803 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
EFDNPGAD_02804 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
EFDNPGAD_02805 2e-45 ytzH S YtzH-like protein
EFDNPGAD_02806 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EFDNPGAD_02807 6.4e-151 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
EFDNPGAD_02808 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
EFDNPGAD_02809 9.8e-52 ytzB S small secreted protein
EFDNPGAD_02810 4.7e-207 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
EFDNPGAD_02811 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
EFDNPGAD_02812 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
EFDNPGAD_02813 9.8e-149 ytpQ S Belongs to the UPF0354 family
EFDNPGAD_02814 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EFDNPGAD_02815 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
EFDNPGAD_02816 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
EFDNPGAD_02817 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EFDNPGAD_02818 6.6e-17 ytxH S COG4980 Gas vesicle protein
EFDNPGAD_02819 4.4e-55 ytxJ O Protein of unknown function (DUF2847)
EFDNPGAD_02820 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
EFDNPGAD_02821 1.7e-182 ccpA K catabolite control protein A
EFDNPGAD_02822 7.1e-147 motA N flagellar motor
EFDNPGAD_02823 1.4e-125 motS N Flagellar motor protein
EFDNPGAD_02824 1.9e-225 acuC BQ histone deacetylase
EFDNPGAD_02825 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
EFDNPGAD_02826 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
EFDNPGAD_02827 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EFDNPGAD_02828 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EFDNPGAD_02830 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EFDNPGAD_02831 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
EFDNPGAD_02832 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
EFDNPGAD_02833 3.4e-109 yttP K Transcriptional regulator
EFDNPGAD_02834 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
EFDNPGAD_02835 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EFDNPGAD_02836 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
EFDNPGAD_02837 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
EFDNPGAD_02838 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EFDNPGAD_02839 2e-29 sspB S spore protein
EFDNPGAD_02840 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EFDNPGAD_02841 0.0 ytcJ S amidohydrolase
EFDNPGAD_02842 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EFDNPGAD_02843 2.4e-181 sppA OU signal peptide peptidase SppA
EFDNPGAD_02844 1.3e-87 yteJ S RDD family
EFDNPGAD_02845 5.6e-116 ytfI S Protein of unknown function (DUF2953)
EFDNPGAD_02846 8.7e-70 ytfJ S Sporulation protein YtfJ
EFDNPGAD_02847 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EFDNPGAD_02848 7e-165 ytxK 2.1.1.72 L DNA methylase
EFDNPGAD_02849 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EFDNPGAD_02850 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
EFDNPGAD_02851 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
EFDNPGAD_02852 3.1e-267 argH 4.3.2.1 E argininosuccinate lyase
EFDNPGAD_02854 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EFDNPGAD_02855 1.7e-130 ytkL S Belongs to the UPF0173 family
EFDNPGAD_02856 2.9e-173 ytlI K LysR substrate binding domain
EFDNPGAD_02857 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
EFDNPGAD_02858 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
EFDNPGAD_02859 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
EFDNPGAD_02860 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
EFDNPGAD_02861 7.6e-121 tcyM U Binding-protein-dependent transport system inner membrane component
EFDNPGAD_02862 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
EFDNPGAD_02863 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EFDNPGAD_02864 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
EFDNPGAD_02865 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EFDNPGAD_02866 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
EFDNPGAD_02867 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
EFDNPGAD_02868 1.2e-158 ytnM S membrane transporter protein
EFDNPGAD_02869 8e-241 ytoI K transcriptional regulator containing CBS domains
EFDNPGAD_02870 2.4e-47 ytpI S YtpI-like protein
EFDNPGAD_02871 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
EFDNPGAD_02872 9.2e-29
EFDNPGAD_02873 8.2e-69 ytrI
EFDNPGAD_02874 3.2e-56 ytrH S Sporulation protein YtrH
EFDNPGAD_02875 0.0 dnaE 2.7.7.7 L DNA polymerase
EFDNPGAD_02876 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
EFDNPGAD_02877 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EFDNPGAD_02878 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
EFDNPGAD_02879 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EFDNPGAD_02880 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
EFDNPGAD_02881 1.8e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
EFDNPGAD_02882 2.6e-192 ytvI S sporulation integral membrane protein YtvI
EFDNPGAD_02883 4.7e-71 yeaL S membrane
EFDNPGAD_02884 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
EFDNPGAD_02885 1.8e-242 icd 1.1.1.42 C isocitrate
EFDNPGAD_02886 1.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
EFDNPGAD_02887 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFDNPGAD_02888 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
EFDNPGAD_02889 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EFDNPGAD_02890 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EFDNPGAD_02891 1.1e-107 ytaF P Probably functions as a manganese efflux pump
EFDNPGAD_02892 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EFDNPGAD_02893 8.9e-161 ytbE S reductase
EFDNPGAD_02894 4.9e-205 ytbD EGP Major facilitator Superfamily
EFDNPGAD_02895 9.9e-67 ytcD K Transcriptional regulator
EFDNPGAD_02896 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EFDNPGAD_02897 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EFDNPGAD_02898 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EFDNPGAD_02899 3.5e-266 dnaB L Membrane attachment protein
EFDNPGAD_02900 3e-173 dnaI L Primosomal protein DnaI
EFDNPGAD_02901 4.9e-111 ytxB S SNARE associated Golgi protein
EFDNPGAD_02902 3.8e-159 ytxC S YtxC-like family
EFDNPGAD_02903 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EFDNPGAD_02904 1.5e-149 ysaA S HAD-hyrolase-like
EFDNPGAD_02905 0.0 lytS 2.7.13.3 T Histidine kinase
EFDNPGAD_02906 6.3e-131 lytT T COG3279 Response regulator of the LytR AlgR family
EFDNPGAD_02907 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
EFDNPGAD_02908 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
EFDNPGAD_02910 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EFDNPGAD_02911 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
EFDNPGAD_02912 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EFDNPGAD_02913 7.5e-45 ysdA S Membrane
EFDNPGAD_02914 9.2e-68 ysdB S Sigma-w pathway protein YsdB
EFDNPGAD_02915 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
EFDNPGAD_02916 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
EFDNPGAD_02917 1.9e-294 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
EFDNPGAD_02918 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
EFDNPGAD_02919 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
EFDNPGAD_02920 4.1e-147 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
EFDNPGAD_02921 5e-226 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
EFDNPGAD_02922 2.8e-254 araN G carbohydrate transport
EFDNPGAD_02923 1.4e-167 araP G carbohydrate transport
EFDNPGAD_02924 3.4e-144 araQ G transport system permease
EFDNPGAD_02925 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
EFDNPGAD_02926 0.0 cstA T Carbon starvation protein
EFDNPGAD_02928 3.6e-38 ysfE 4.4.1.5 E lactoylglutathione lyase activity
EFDNPGAD_02929 5.6e-258 glcF C Glycolate oxidase
EFDNPGAD_02930 7.2e-264 glcD 1.1.3.15 C Glycolate oxidase subunit
EFDNPGAD_02931 4.4e-208 ysfB KT regulator
EFDNPGAD_02932 2.6e-32 sspI S Belongs to the SspI family
EFDNPGAD_02933 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EFDNPGAD_02934 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EFDNPGAD_02935 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EFDNPGAD_02936 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EFDNPGAD_02937 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EFDNPGAD_02938 1.3e-85 cvpA S membrane protein, required for colicin V production
EFDNPGAD_02939 0.0 polX L COG1796 DNA polymerase IV (family X)
EFDNPGAD_02940 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EFDNPGAD_02941 7.3e-68 yshE S membrane
EFDNPGAD_02942 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EFDNPGAD_02943 2.7e-100 fadR K Transcriptional regulator
EFDNPGAD_02944 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
EFDNPGAD_02945 1.2e-135 etfB C Electron transfer flavoprotein
EFDNPGAD_02946 4.2e-178 etfA C Electron transfer flavoprotein
EFDNPGAD_02948 4e-305 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
EFDNPGAD_02949 2e-52 trxA O Belongs to the thioredoxin family
EFDNPGAD_02950 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EFDNPGAD_02951 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
EFDNPGAD_02952 1.2e-79 yslB S Protein of unknown function (DUF2507)
EFDNPGAD_02953 2.4e-107 sdhC C succinate dehydrogenase
EFDNPGAD_02954 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
EFDNPGAD_02955 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
EFDNPGAD_02956 7.7e-79 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
EFDNPGAD_02957 3.3e-30 gerE K Transcriptional regulator
EFDNPGAD_02958 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
EFDNPGAD_02959 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
EFDNPGAD_02960 2.9e-196 gerM S COG5401 Spore germination protein
EFDNPGAD_02961 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EFDNPGAD_02962 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EFDNPGAD_02963 1.4e-92 ysnB S Phosphoesterase
EFDNPGAD_02965 9.1e-134 ysnF S protein conserved in bacteria
EFDNPGAD_02966 7.6e-82 ysnE K acetyltransferase
EFDNPGAD_02968 0.0 ilvB 2.2.1.6 E Acetolactate synthase
EFDNPGAD_02969 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
EFDNPGAD_02970 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EFDNPGAD_02971 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EFDNPGAD_02972 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
EFDNPGAD_02973 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EFDNPGAD_02974 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EFDNPGAD_02975 2.3e-187 ysoA H Tetratricopeptide repeat
EFDNPGAD_02976 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EFDNPGAD_02977 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EFDNPGAD_02978 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
EFDNPGAD_02979 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EFDNPGAD_02980 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
EFDNPGAD_02981 1.4e-89 ysxD
EFDNPGAD_02982 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EFDNPGAD_02983 3.6e-146 hemX O cytochrome C
EFDNPGAD_02984 3e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
EFDNPGAD_02985 4.4e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
EFDNPGAD_02986 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
EFDNPGAD_02987 4.6e-249 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
EFDNPGAD_02988 1.9e-226 spoVID M stage VI sporulation protein D
EFDNPGAD_02989 1.6e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EFDNPGAD_02990 1.6e-25
EFDNPGAD_02991 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EFDNPGAD_02992 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EFDNPGAD_02993 6.6e-85 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
EFDNPGAD_02994 1.1e-168 spoIIB S Sporulation related domain
EFDNPGAD_02995 2.8e-102 maf D septum formation protein Maf
EFDNPGAD_02996 5.9e-126 radC E Belongs to the UPF0758 family
EFDNPGAD_02997 1.8e-184 mreB D Rod shape-determining protein MreB
EFDNPGAD_02998 2.8e-157 mreC M Involved in formation and maintenance of cell shape
EFDNPGAD_02999 1.4e-84 mreD M shape-determining protein
EFDNPGAD_03000 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
EFDNPGAD_03001 2.5e-144 minD D Belongs to the ParA family
EFDNPGAD_03002 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
EFDNPGAD_03003 9.2e-161 spoIVFB S Stage IV sporulation protein
EFDNPGAD_03004 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
EFDNPGAD_03005 4.1e-56 ysxB J ribosomal protein
EFDNPGAD_03006 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
EFDNPGAD_03007 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
EFDNPGAD_03008 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EFDNPGAD_03009 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
EFDNPGAD_03010 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
EFDNPGAD_03011 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
EFDNPGAD_03012 1.2e-230 nifS 2.8.1.7 E Cysteine desulfurase
EFDNPGAD_03013 2.7e-307 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
EFDNPGAD_03014 5.4e-161 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
EFDNPGAD_03015 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EFDNPGAD_03016 9.8e-158 safA M spore coat assembly protein SafA
EFDNPGAD_03017 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EFDNPGAD_03018 1.9e-127 yebC K transcriptional regulatory protein
EFDNPGAD_03019 1.8e-262 alsT E Sodium alanine symporter
EFDNPGAD_03020 2.6e-35 S Family of unknown function (DUF5412)
EFDNPGAD_03022 6.5e-119 yrzF T serine threonine protein kinase
EFDNPGAD_03023 1.3e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
EFDNPGAD_03024 5.3e-253 csbX EGP Major facilitator Superfamily
EFDNPGAD_03025 4.8e-93 bofC S BofC C-terminal domain
EFDNPGAD_03026 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EFDNPGAD_03027 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EFDNPGAD_03028 2.6e-18 yrzS S Protein of unknown function (DUF2905)
EFDNPGAD_03029 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EFDNPGAD_03030 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EFDNPGAD_03031 1.1e-38 yajC U Preprotein translocase subunit YajC
EFDNPGAD_03032 1.2e-74 yrzE S Protein of unknown function (DUF3792)
EFDNPGAD_03033 2.2e-114 yrbG S membrane
EFDNPGAD_03034 5.7e-270 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EFDNPGAD_03035 9.4e-49 yrzD S Post-transcriptional regulator
EFDNPGAD_03036 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EFDNPGAD_03037 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
EFDNPGAD_03038 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
EFDNPGAD_03039 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
EFDNPGAD_03040 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EFDNPGAD_03041 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EFDNPGAD_03042 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EFDNPGAD_03043 3.9e-263 lytH 3.5.1.28 M COG3103 SH3 domain protein
EFDNPGAD_03045 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
EFDNPGAD_03046 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EFDNPGAD_03047 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
EFDNPGAD_03048 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
EFDNPGAD_03049 1.2e-70 cymR K Transcriptional regulator
EFDNPGAD_03050 4.7e-213 iscS 2.8.1.7 E Cysteine desulfurase
EFDNPGAD_03051 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EFDNPGAD_03052 1.4e-15 S COG0457 FOG TPR repeat
EFDNPGAD_03053 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EFDNPGAD_03054 1.8e-83 yrrD S protein conserved in bacteria
EFDNPGAD_03055 9.8e-31 yrzR
EFDNPGAD_03056 8e-08 S Protein of unknown function (DUF3918)
EFDNPGAD_03057 7.6e-107 glnP P ABC transporter
EFDNPGAD_03058 3.6e-109 gluC P ABC transporter
EFDNPGAD_03059 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
EFDNPGAD_03060 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
EFDNPGAD_03061 2.7e-170 yrrI S AI-2E family transporter
EFDNPGAD_03062 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EFDNPGAD_03063 1.7e-41 yrzL S Belongs to the UPF0297 family
EFDNPGAD_03064 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EFDNPGAD_03065 1.2e-45 yrzB S Belongs to the UPF0473 family
EFDNPGAD_03066 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EFDNPGAD_03067 5.9e-120 yrrM 2.1.1.104 S O-methyltransferase
EFDNPGAD_03068 7.8e-174 yegQ O Peptidase U32
EFDNPGAD_03069 2.7e-246 yegQ O COG0826 Collagenase and related proteases
EFDNPGAD_03070 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
EFDNPGAD_03071 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EFDNPGAD_03072 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
EFDNPGAD_03073 4.2e-63 yrrS S Protein of unknown function (DUF1510)
EFDNPGAD_03074 3.5e-26 yrzA S Protein of unknown function (DUF2536)
EFDNPGAD_03075 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
EFDNPGAD_03076 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EFDNPGAD_03077 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
EFDNPGAD_03078 2.6e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EFDNPGAD_03079 4.6e-35 yrhC S YrhC-like protein
EFDNPGAD_03080 1.4e-78 yrhD S Protein of unknown function (DUF1641)
EFDNPGAD_03081 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
EFDNPGAD_03082 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
EFDNPGAD_03083 1.8e-142 focA P Formate nitrite
EFDNPGAD_03086 4.5e-97 yrhH Q methyltransferase
EFDNPGAD_03087 4.8e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
EFDNPGAD_03088 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
EFDNPGAD_03089 1.5e-46 yrhK S YrhK-like protein
EFDNPGAD_03090 0.0 yrhL I Acyltransferase family
EFDNPGAD_03091 1.7e-151 rsiV S Protein of unknown function (DUF3298)
EFDNPGAD_03092 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
EFDNPGAD_03093 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
EFDNPGAD_03094 3.6e-106 yrhP E LysE type translocator
EFDNPGAD_03095 1.6e-255 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
EFDNPGAD_03096 0.0 levR K PTS system fructose IIA component
EFDNPGAD_03097 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
EFDNPGAD_03098 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
EFDNPGAD_03099 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
EFDNPGAD_03100 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
EFDNPGAD_03101 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
EFDNPGAD_03102 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
EFDNPGAD_03103 1.9e-200 adhA 1.1.1.1 C alcohol dehydrogenase
EFDNPGAD_03104 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
EFDNPGAD_03105 4.3e-47 yraB K helix_turn_helix, mercury resistance
EFDNPGAD_03106 1.1e-49 yraD M Spore coat protein
EFDNPGAD_03107 2.6e-26 yraE
EFDNPGAD_03108 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EFDNPGAD_03109 6.4e-63 yraF M Spore coat protein
EFDNPGAD_03110 5.3e-37 yraG
EFDNPGAD_03111 1.3e-66 E Glyoxalase-like domain
EFDNPGAD_03112 2.4e-61 T sh3 domain protein
EFDNPGAD_03113 1.7e-60 T sh3 domain protein
EFDNPGAD_03114 3.2e-155 S Alpha beta hydrolase
EFDNPGAD_03115 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EFDNPGAD_03116 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
EFDNPGAD_03118 2.4e-206 yraM S PrpF protein
EFDNPGAD_03119 1.2e-163 yraN K Transcriptional regulator
EFDNPGAD_03120 9.5e-226 yraO C Citrate transporter
EFDNPGAD_03121 4.5e-188 yrpG C Aldo/keto reductase family
EFDNPGAD_03122 6.3e-96 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
EFDNPGAD_03123 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
EFDNPGAD_03125 3e-125 yrpD S Domain of unknown function, YrpD
EFDNPGAD_03126 7.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
EFDNPGAD_03127 1.5e-194 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
EFDNPGAD_03128 7.6e-168 aadK G Streptomycin adenylyltransferase
EFDNPGAD_03129 1.2e-91 yrdA S DinB family
EFDNPGAD_03130 1.9e-57 S Protein of unknown function (DUF2568)
EFDNPGAD_03131 3.1e-101 yrdC 3.5.1.19 Q Isochorismatase family
EFDNPGAD_03132 4.1e-231 cypA C Cytochrome P450
EFDNPGAD_03133 4.1e-46 yrdF K ribonuclease inhibitor
EFDNPGAD_03134 2.2e-79 bkdR K helix_turn_helix ASNC type
EFDNPGAD_03135 3.3e-138 azlC E AzlC protein
EFDNPGAD_03136 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
EFDNPGAD_03137 1.5e-231 brnQ E Component of the transport system for branched-chain amino acids
EFDNPGAD_03139 7.7e-163 gltR K LysR substrate binding domain
EFDNPGAD_03140 1.3e-66 yodA S tautomerase
EFDNPGAD_03141 3.5e-158 czcD P COG1230 Co Zn Cd efflux system component
EFDNPGAD_03142 2e-199 trkA P Oxidoreductase
EFDNPGAD_03143 5.9e-160 yrdQ K Transcriptional regulator
EFDNPGAD_03144 1.7e-171 yrdR EG EamA-like transporter family
EFDNPGAD_03145 2.1e-17 S YrzO-like protein
EFDNPGAD_03146 4.5e-236 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
EFDNPGAD_03147 1.4e-83 bltD 2.3.1.57 K FR47-like protein
EFDNPGAD_03148 3.5e-211 blt EGP Major facilitator Superfamily
EFDNPGAD_03149 4.8e-151 bltR K helix_turn_helix, mercury resistance
EFDNPGAD_03150 2.6e-108 yrkC G Cupin domain
EFDNPGAD_03151 7.8e-39 yrkD S protein conserved in bacteria
EFDNPGAD_03152 5.1e-84 yrkE O DsrE/DsrF/DrsH-like family
EFDNPGAD_03153 1.7e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
EFDNPGAD_03154 2.3e-212 yrkH P Rhodanese Homology Domain
EFDNPGAD_03155 2.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
EFDNPGAD_03156 4.3e-117 yrkJ S membrane transporter protein
EFDNPGAD_03157 2.8e-79 S Protein of unknown function with HXXEE motif
EFDNPGAD_03158 1.5e-97 ywrO S Flavodoxin-like fold
EFDNPGAD_03159 6e-105 yrkN K Acetyltransferase (GNAT) family
EFDNPGAD_03160 8.2e-224 yrkO P Protein of unknown function (DUF418)
EFDNPGAD_03161 1.1e-127 T Transcriptional regulator
EFDNPGAD_03162 9e-237 yrkQ T Histidine kinase
EFDNPGAD_03163 2e-68 psiE S Protein PsiE homolog
EFDNPGAD_03164 2.6e-59 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EFDNPGAD_03165 6.7e-167 ygxA S Nucleotidyltransferase-like
EFDNPGAD_03166 1.5e-56 ygzB S UPF0295 protein
EFDNPGAD_03167 4e-80 perR P Belongs to the Fur family
EFDNPGAD_03168 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
EFDNPGAD_03169 1.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
EFDNPGAD_03170 8.7e-180 ygaE S Membrane
EFDNPGAD_03171 1.8e-301 ygaD V ABC transporter
EFDNPGAD_03172 1.3e-104 ygaC J Belongs to the UPF0374 family
EFDNPGAD_03173 1.5e-37 ygaB S YgaB-like protein
EFDNPGAD_03174 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
EFDNPGAD_03175 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EFDNPGAD_03176 6.9e-36 yfhS
EFDNPGAD_03177 7.8e-212 mutY L A G-specific
EFDNPGAD_03178 5.5e-186 yfhP S membrane-bound metal-dependent
EFDNPGAD_03179 0.0 yfhO S Bacterial membrane protein YfhO
EFDNPGAD_03180 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EFDNPGAD_03181 6.7e-172 yfhM S Alpha beta hydrolase
EFDNPGAD_03182 3.5e-51 yfhL S SdpI/YhfL protein family
EFDNPGAD_03183 9.2e-92 batE T Bacterial SH3 domain homologues
EFDNPGAD_03184 1.3e-44 yfhJ S WVELL protein
EFDNPGAD_03185 6.2e-20 sspK S reproduction
EFDNPGAD_03186 1.1e-209 yfhI EGP Major facilitator Superfamily
EFDNPGAD_03188 9.7e-52 yfhH S Protein of unknown function (DUF1811)
EFDNPGAD_03189 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
EFDNPGAD_03190 4.9e-173 yfhF S nucleoside-diphosphate sugar epimerase
EFDNPGAD_03192 2.1e-25 yfhD S YfhD-like protein
EFDNPGAD_03193 3.9e-107 yfhC C nitroreductase
EFDNPGAD_03194 1.8e-167 yfhB 5.3.3.17 S PhzF family
EFDNPGAD_03195 5.2e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFDNPGAD_03196 3.1e-176 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFDNPGAD_03197 6.2e-182 yfiY P ABC transporter substrate-binding protein
EFDNPGAD_03198 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EFDNPGAD_03199 3.1e-81 yfiV K transcriptional
EFDNPGAD_03200 8.7e-287 yfiU EGP Major facilitator Superfamily
EFDNPGAD_03201 3.3e-100 yfiT S Belongs to the metal hydrolase YfiT family
EFDNPGAD_03202 5.1e-221 yfiS EGP Major facilitator Superfamily
EFDNPGAD_03203 2e-109 yfiR K Transcriptional regulator
EFDNPGAD_03204 9e-198 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EFDNPGAD_03205 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
EFDNPGAD_03206 8.3e-99 padR K transcriptional
EFDNPGAD_03207 4.6e-208 V COG0842 ABC-type multidrug transport system, permease component
EFDNPGAD_03208 9.8e-214 V ABC-2 family transporter protein
EFDNPGAD_03209 6.2e-171 V ABC transporter, ATP-binding protein
EFDNPGAD_03210 3.2e-113 KT LuxR family transcriptional regulator
EFDNPGAD_03211 1.1e-214 yxjM T Histidine kinase
EFDNPGAD_03213 1.1e-233 S Oxidoreductase
EFDNPGAD_03214 8.4e-184 G Xylose isomerase
EFDNPGAD_03215 1.8e-262 iolT EGP Major facilitator Superfamily
EFDNPGAD_03216 1.5e-177 K AraC-like ligand binding domain
EFDNPGAD_03217 5.7e-163 yfiE 1.13.11.2 S glyoxalase
EFDNPGAD_03218 9.8e-65 mhqP S DoxX
EFDNPGAD_03219 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
EFDNPGAD_03220 2.1e-310 yfiB3 V ABC transporter
EFDNPGAD_03221 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EFDNPGAD_03222 3.2e-141 glvR K Helix-turn-helix domain, rpiR family
EFDNPGAD_03223 9.9e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EFDNPGAD_03224 1.1e-44 yfjA S Belongs to the WXG100 family
EFDNPGAD_03225 9.2e-191 yfjB
EFDNPGAD_03226 4.1e-144 yfjC
EFDNPGAD_03227 1.8e-101 yfjD S Family of unknown function (DUF5381)
EFDNPGAD_03228 1.3e-80 S Family of unknown function (DUF5381)
EFDNPGAD_03229 4e-56 yfjF S UPF0060 membrane protein
EFDNPGAD_03230 1.2e-25 sspH S Belongs to the SspH family
EFDNPGAD_03231 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
EFDNPGAD_03232 6.4e-257 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EFDNPGAD_03233 2.9e-197 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EFDNPGAD_03234 1e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EFDNPGAD_03235 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EFDNPGAD_03236 3e-29 yfjL
EFDNPGAD_03237 1.1e-61 yfjM S Psort location Cytoplasmic, score
EFDNPGAD_03238 5.1e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EFDNPGAD_03239 1.6e-39 S YfzA-like protein
EFDNPGAD_03240 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EFDNPGAD_03241 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EFDNPGAD_03242 1.7e-184 corA P Mediates influx of magnesium ions
EFDNPGAD_03243 4.2e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
EFDNPGAD_03244 2.6e-154 pdaA G deacetylase
EFDNPGAD_03245 1.1e-26 yfjT
EFDNPGAD_03246 5.4e-222 yfkA S YfkB-like domain
EFDNPGAD_03247 6e-149 yfkC M Mechanosensitive ion channel
EFDNPGAD_03248 1.2e-146 yfkD S YfkD-like protein
EFDNPGAD_03249 6.1e-183 cax P COG0387 Ca2 H antiporter
EFDNPGAD_03250 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
EFDNPGAD_03251 5e-08
EFDNPGAD_03252 9.7e-144 yihY S Belongs to the UPF0761 family
EFDNPGAD_03253 8.4e-51 yfkI S gas vesicle protein
EFDNPGAD_03254 2.2e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EFDNPGAD_03255 2.1e-29 yfkK S Belongs to the UPF0435 family
EFDNPGAD_03256 6.8e-207 ydiM EGP Major facilitator Superfamily
EFDNPGAD_03257 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
EFDNPGAD_03258 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
EFDNPGAD_03259 1.6e-125 yfkO C nitroreductase
EFDNPGAD_03260 1.8e-133 treR K transcriptional
EFDNPGAD_03261 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
EFDNPGAD_03262 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EFDNPGAD_03263 1.5e-283 yfkQ EG Spore germination protein
EFDNPGAD_03264 5.1e-207 yfkR S spore germination
EFDNPGAD_03266 1.6e-194 E Spore germination protein
EFDNPGAD_03267 3.2e-256 agcS_1 E Sodium alanine symporter
EFDNPGAD_03268 6e-67 yhdN S Domain of unknown function (DUF1992)
EFDNPGAD_03269 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
EFDNPGAD_03270 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
EFDNPGAD_03271 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
EFDNPGAD_03272 2.4e-50 yflH S Protein of unknown function (DUF3243)
EFDNPGAD_03273 4.1e-19 yflI
EFDNPGAD_03274 4e-18 yflJ S Protein of unknown function (DUF2639)
EFDNPGAD_03275 9e-124 yflK S protein conserved in bacteria
EFDNPGAD_03276 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
EFDNPGAD_03277 1.3e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EFDNPGAD_03278 5.5e-152 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
EFDNPGAD_03279 8.5e-227 citM C Citrate transporter
EFDNPGAD_03281 3e-181 yflP S Tripartite tricarboxylate transporter family receptor
EFDNPGAD_03282 8.9e-119 citT T response regulator
EFDNPGAD_03283 1e-290 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
EFDNPGAD_03284 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
EFDNPGAD_03285 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
EFDNPGAD_03286 7.6e-58 yflT S Heat induced stress protein YflT
EFDNPGAD_03287 2.9e-24 S Protein of unknown function (DUF3212)
EFDNPGAD_03288 3.4e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
EFDNPGAD_03289 4.3e-170 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFDNPGAD_03290 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFDNPGAD_03291 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
EFDNPGAD_03292 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
EFDNPGAD_03293 7.7e-214 G Major Facilitator Superfamily
EFDNPGAD_03294 8.5e-190 yfmJ S N-terminal domain of oxidoreductase
EFDNPGAD_03295 7.5e-82 yfmK 2.3.1.128 K acetyltransferase
EFDNPGAD_03296 6.3e-202 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
EFDNPGAD_03297 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EFDNPGAD_03298 1.5e-209 yfmO EGP Major facilitator Superfamily
EFDNPGAD_03299 2.8e-70 yfmP K transcriptional
EFDNPGAD_03300 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
EFDNPGAD_03301 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EFDNPGAD_03302 1.1e-113 yfmS NT chemotaxis protein
EFDNPGAD_03303 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EFDNPGAD_03304 1.3e-241 yfnA E amino acid
EFDNPGAD_03305 7.8e-134 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
EFDNPGAD_03306 2e-206 fsr P COG0477 Permeases of the major facilitator superfamily
EFDNPGAD_03307 3.5e-190 yfnD M Nucleotide-diphospho-sugar transferase
EFDNPGAD_03308 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
EFDNPGAD_03309 3.8e-181 yfnF M Nucleotide-diphospho-sugar transferase
EFDNPGAD_03310 1.9e-172 yfnG 4.2.1.45 M dehydratase
EFDNPGAD_03311 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
EFDNPGAD_03312 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
EFDNPGAD_03313 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
EFDNPGAD_03314 3.6e-199 yetN S Protein of unknown function (DUF3900)
EFDNPGAD_03315 7.8e-213 yetM CH FAD binding domain
EFDNPGAD_03316 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
EFDNPGAD_03317 5.4e-159 yetK EG EamA-like transporter family
EFDNPGAD_03318 5.3e-105 yetJ S Belongs to the BI1 family
EFDNPGAD_03319 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
EFDNPGAD_03320 4.4e-43 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EFDNPGAD_03321 2.2e-89 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EFDNPGAD_03322 2.2e-34
EFDNPGAD_03323 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EFDNPGAD_03324 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
EFDNPGAD_03325 6.1e-123 yetF S membrane
EFDNPGAD_03326 3.3e-258 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
EFDNPGAD_03327 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
EFDNPGAD_03328 1.3e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
EFDNPGAD_03329 9.6e-291 lplA G Bacterial extracellular solute-binding protein
EFDNPGAD_03330 0.0 yetA
EFDNPGAD_03331 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
EFDNPGAD_03332 3e-124 yesY E GDSL-like Lipase/Acylhydrolase
EFDNPGAD_03333 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
EFDNPGAD_03334 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
EFDNPGAD_03335 1e-113 yesV S Protein of unknown function, DUF624
EFDNPGAD_03336 8.9e-132 yesU S Domain of unknown function (DUF1961)
EFDNPGAD_03337 3.8e-133 E GDSL-like Lipase/Acylhydrolase
EFDNPGAD_03338 0.0 yesS K Transcriptional regulator
EFDNPGAD_03339 1.6e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
EFDNPGAD_03340 1.3e-165 yesQ P Binding-protein-dependent transport system inner membrane component
EFDNPGAD_03341 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
EFDNPGAD_03342 5e-248 yesO G Bacterial extracellular solute-binding protein
EFDNPGAD_03343 2.9e-204 yesN K helix_turn_helix, arabinose operon control protein
EFDNPGAD_03344 0.0 yesM 2.7.13.3 T Histidine kinase
EFDNPGAD_03345 4.4e-104 yesL S Protein of unknown function, DUF624
EFDNPGAD_03347 4.2e-103 yesJ K Acetyltransferase (GNAT) family
EFDNPGAD_03348 5.2e-104 cotJC P Spore Coat
EFDNPGAD_03349 1.5e-45 cotJB S CotJB protein
EFDNPGAD_03350 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
EFDNPGAD_03351 2.2e-159 yesF GM NAD(P)H-binding
EFDNPGAD_03352 9.7e-82 yesE S SnoaL-like domain
EFDNPGAD_03353 1.2e-103 dhaR3 K Transcriptional regulator
EFDNPGAD_03355 9.4e-127 yeeN K transcriptional regulatory protein
EFDNPGAD_03357 5.5e-214 S Tetratricopeptide repeat
EFDNPGAD_03358 1.8e-192 3.4.24.40 CO amine dehydrogenase activity
EFDNPGAD_03359 0.0 L nucleic acid phosphodiester bond hydrolysis
EFDNPGAD_03360 5.5e-83 S Protein of unknown function, DUF600
EFDNPGAD_03361 6.2e-31 S Colicin immunity protein / pyocin immunity protein
EFDNPGAD_03363 1.2e-211 pstS P T5orf172
EFDNPGAD_03364 0.0 yeeB L DEAD-like helicases superfamily
EFDNPGAD_03365 0.0 yeeA V Type II restriction enzyme, methylase subunits
EFDNPGAD_03366 8.5e-139 yeeA V Type II restriction enzyme, methylase subunits
EFDNPGAD_03367 3.2e-53 L Resolvase, N terminal domain
EFDNPGAD_03368 3.2e-98 L Recombinase
EFDNPGAD_03369 1.2e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EFDNPGAD_03370 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EFDNPGAD_03371 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EFDNPGAD_03372 4e-156 yerO K Transcriptional regulator
EFDNPGAD_03373 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EFDNPGAD_03374 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EFDNPGAD_03375 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EFDNPGAD_03376 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EFDNPGAD_03377 1.6e-123 sapB S MgtC SapB transporter
EFDNPGAD_03378 1.1e-197 yerI S homoserine kinase type II (protein kinase fold)
EFDNPGAD_03379 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
EFDNPGAD_03380 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EFDNPGAD_03381 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
EFDNPGAD_03382 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EFDNPGAD_03384 3.2e-305 yerD 1.4.7.1 E Belongs to the glutamate synthase family
EFDNPGAD_03385 4.8e-51 yerC S protein conserved in bacteria
EFDNPGAD_03386 3e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
EFDNPGAD_03387 0.0 yerA 3.5.4.2 F adenine deaminase
EFDNPGAD_03388 2.7e-27 S Protein of unknown function (DUF2892)
EFDNPGAD_03389 2.3e-232 yjeH E Amino acid permease
EFDNPGAD_03390 3.5e-73 K helix_turn_helix ASNC type
EFDNPGAD_03391 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
EFDNPGAD_03392 1.2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
EFDNPGAD_03393 1.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EFDNPGAD_03394 7.6e-178 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
EFDNPGAD_03395 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EFDNPGAD_03396 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EFDNPGAD_03397 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EFDNPGAD_03398 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EFDNPGAD_03399 1.2e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
EFDNPGAD_03400 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EFDNPGAD_03401 7e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EFDNPGAD_03402 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EFDNPGAD_03403 8e-28 yebG S NETI protein
EFDNPGAD_03404 4e-93 yebE S UPF0316 protein
EFDNPGAD_03406 1.1e-118 yebC M Membrane
EFDNPGAD_03407 6e-212 pbuG S permease
EFDNPGAD_03408 3.7e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
EFDNPGAD_03409 0.0 yebA E COG1305 Transglutaminase-like enzymes
EFDNPGAD_03410 9.5e-225 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
EFDNPGAD_03411 1.6e-177 yeaC S COG0714 MoxR-like ATPases
EFDNPGAD_03412 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EFDNPGAD_03413 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
EFDNPGAD_03414 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
EFDNPGAD_03415 2.4e-181 yeaA S Protein of unknown function (DUF4003)
EFDNPGAD_03416 9.5e-160 ydjP I Alpha/beta hydrolase family
EFDNPGAD_03417 1.4e-34 ydjO S Cold-inducible protein YdjO
EFDNPGAD_03419 4.4e-157 ydjN U Involved in the tonB-independent uptake of proteins
EFDNPGAD_03420 4.5e-64 ydjM M Lytic transglycolase
EFDNPGAD_03421 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
EFDNPGAD_03422 2.7e-258 iolT EGP Major facilitator Superfamily
EFDNPGAD_03423 4.7e-196 S Ion transport 2 domain protein
EFDNPGAD_03424 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
EFDNPGAD_03425 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
EFDNPGAD_03426 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EFDNPGAD_03427 5.1e-114 pspA KT Phage shock protein A
EFDNPGAD_03428 1.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
EFDNPGAD_03429 7.1e-256 gutA G MFS/sugar transport protein
EFDNPGAD_03430 3.8e-201 gutB 1.1.1.14 E Dehydrogenase
EFDNPGAD_03431 0.0 K NB-ARC domain
EFDNPGAD_03432 1.1e-08 ydjC S Abhydrolase domain containing 18
EFDNPGAD_03433 4.9e-257 J LlaJI restriction endonuclease
EFDNPGAD_03434 1.2e-199 V AAA domain (dynein-related subfamily)
EFDNPGAD_03436 1.6e-232 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
EFDNPGAD_03437 1.1e-250 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
EFDNPGAD_03438 6.4e-66 KL Phage plasmid primase P4 family
EFDNPGAD_03440 1.2e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EFDNPGAD_03441 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EFDNPGAD_03442 7.9e-129 ydiL S CAAX protease self-immunity
EFDNPGAD_03443 2.9e-27 ydiK S Domain of unknown function (DUF4305)
EFDNPGAD_03444 8.4e-126 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EFDNPGAD_03445 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EFDNPGAD_03446 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EFDNPGAD_03447 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
EFDNPGAD_03448 0.0 ydiF S ABC transporter
EFDNPGAD_03449 3.6e-188 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EFDNPGAD_03450 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
EFDNPGAD_03451 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
EFDNPGAD_03452 9.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
EFDNPGAD_03453 4.6e-185 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EFDNPGAD_03455 7.8e-08
EFDNPGAD_03456 1.3e-63 hxlR K transcriptional
EFDNPGAD_03457 3.3e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
EFDNPGAD_03458 4.6e-97 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
EFDNPGAD_03459 3e-187 tlpC 2.7.13.3 NT chemotaxis protein
EFDNPGAD_03460 3.2e-72 nucA M Deoxyribonuclease NucA/NucB
EFDNPGAD_03461 3.4e-70 nin S Competence protein J (ComJ)
EFDNPGAD_03462 1.2e-298 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EFDNPGAD_03463 3.5e-52 yckD S Protein of unknown function (DUF2680)
EFDNPGAD_03464 3.3e-77 yckC S membrane
EFDNPGAD_03467 1.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
EFDNPGAD_03468 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
EFDNPGAD_03469 1.4e-228 yciC S GTPases (G3E family)
EFDNPGAD_03470 5.5e-109 yciB M ErfK YbiS YcfS YnhG
EFDNPGAD_03471 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
EFDNPGAD_03472 6.4e-221 nasA P COG2223 Nitrate nitrite transporter
EFDNPGAD_03473 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
EFDNPGAD_03474 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EFDNPGAD_03475 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EFDNPGAD_03476 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
EFDNPGAD_03477 9.3e-283 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
EFDNPGAD_03478 1.3e-193 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
EFDNPGAD_03479 5.7e-163 I alpha/beta hydrolase fold
EFDNPGAD_03480 1.2e-139 ycgR S permeases
EFDNPGAD_03481 2.6e-147 ycgQ S membrane
EFDNPGAD_03482 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
EFDNPGAD_03483 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EFDNPGAD_03484 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
EFDNPGAD_03485 5.1e-170 ycgM E Proline dehydrogenase
EFDNPGAD_03486 2.9e-145 ycgL S Predicted nucleotidyltransferase
EFDNPGAD_03487 2.9e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
EFDNPGAD_03488 2.2e-179 oxyR3 K LysR substrate binding domain
EFDNPGAD_03489 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
EFDNPGAD_03490 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EFDNPGAD_03491 2.5e-109 tmrB S AAA domain
EFDNPGAD_03492 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EFDNPGAD_03493 2.4e-112 ycgI S Domain of unknown function (DUF1989)
EFDNPGAD_03494 5.6e-250 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
EFDNPGAD_03495 1.2e-151 yqcI S YqcI/YcgG family
EFDNPGAD_03496 6.8e-113 ycgF E Lysine exporter protein LysE YggA
EFDNPGAD_03497 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
EFDNPGAD_03498 6.2e-269 mdr EGP Major facilitator Superfamily
EFDNPGAD_03499 6.5e-293 lctP C L-lactate permease
EFDNPGAD_03500 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
EFDNPGAD_03501 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
EFDNPGAD_03502 1.1e-98 ycgB
EFDNPGAD_03503 8.7e-257 ycgA S Membrane
EFDNPGAD_03504 1.2e-219 amhX S amidohydrolase
EFDNPGAD_03505 5.3e-164 opuAC E glycine betaine
EFDNPGAD_03506 1.3e-127 opuAB P glycine betaine
EFDNPGAD_03507 5.1e-229 proV 3.6.3.32 E glycine betaine
EFDNPGAD_03508 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
EFDNPGAD_03509 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
EFDNPGAD_03510 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
EFDNPGAD_03511 2e-192 yceH P Belongs to the TelA family
EFDNPGAD_03512 0.0 yceG S Putative component of 'biosynthetic module'
EFDNPGAD_03513 6.3e-137 terC P Protein of unknown function (DUF475)
EFDNPGAD_03514 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
EFDNPGAD_03515 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
EFDNPGAD_03516 3.9e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
EFDNPGAD_03517 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EFDNPGAD_03518 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
EFDNPGAD_03519 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
EFDNPGAD_03520 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
EFDNPGAD_03521 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
EFDNPGAD_03522 3.9e-19 IQ Enoyl-(Acyl carrier protein) reductase
EFDNPGAD_03523 2e-109 IQ Enoyl-(Acyl carrier protein) reductase
EFDNPGAD_03524 5.5e-174 S response regulator aspartate phosphatase
EFDNPGAD_03525 1.7e-95 cwlK M D-alanyl-D-alanine carboxypeptidase
EFDNPGAD_03526 6.7e-268 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
EFDNPGAD_03527 5.9e-282 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
EFDNPGAD_03528 6.6e-177 ycdA S Domain of unknown function (DUF5105)
EFDNPGAD_03529 1.6e-174 yccK C Aldo keto reductase
EFDNPGAD_03530 4.5e-203 natB CP ABC-2 family transporter protein
EFDNPGAD_03531 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
EFDNPGAD_03532 7.8e-126 lytR_2 T LytTr DNA-binding domain
EFDNPGAD_03533 2e-161 2.7.13.3 T GHKL domain
EFDNPGAD_03534 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
EFDNPGAD_03535 2e-59 S RDD family
EFDNPGAD_03536 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
EFDNPGAD_03537 2.2e-202 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
EFDNPGAD_03538 4.8e-102 yxaF K Transcriptional regulator
EFDNPGAD_03539 5.8e-229 lmrB EGP the major facilitator superfamily
EFDNPGAD_03540 6.2e-210 ycbU E Selenocysteine lyase
EFDNPGAD_03541 1.4e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EFDNPGAD_03542 1.2e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EFDNPGAD_03543 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EFDNPGAD_03544 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
EFDNPGAD_03545 6.6e-136 ycbR T vWA found in TerF C terminus
EFDNPGAD_03546 1.3e-78 sleB 3.5.1.28 M Cell wall
EFDNPGAD_03547 8.2e-53 ycbP S Protein of unknown function (DUF2512)
EFDNPGAD_03548 2.1e-115 S ABC-2 family transporter protein
EFDNPGAD_03549 4.8e-168 ycbN V ABC transporter, ATP-binding protein
EFDNPGAD_03550 2.4e-170 T PhoQ Sensor
EFDNPGAD_03551 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFDNPGAD_03552 7.3e-172 eamA1 EG spore germination
EFDNPGAD_03553 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
EFDNPGAD_03554 1.8e-178 ycbJ S Macrolide 2'-phosphotransferase
EFDNPGAD_03555 3.7e-298 garD 4.2.1.42, 4.2.1.7 G Altronate
EFDNPGAD_03556 1.5e-124 ycbG K FCD
EFDNPGAD_03557 2.2e-270 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
EFDNPGAD_03558 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
EFDNPGAD_03559 3.7e-274 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EFDNPGAD_03560 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
EFDNPGAD_03561 9e-170 glnL T Regulator
EFDNPGAD_03562 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
EFDNPGAD_03563 1.5e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
EFDNPGAD_03564 2.3e-257 agcS E Sodium alanine symporter
EFDNPGAD_03565 9.3e-183 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
EFDNPGAD_03566 6.7e-262 mmuP E amino acid
EFDNPGAD_03567 5.4e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
EFDNPGAD_03569 4.9e-128 K UTRA
EFDNPGAD_03570 2.1e-137 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EFDNPGAD_03571 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EFDNPGAD_03572 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EFDNPGAD_03573 3.9e-192 yceA S Belongs to the UPF0176 family
EFDNPGAD_03574 6.7e-167 ybfP K Transcriptional regulator
EFDNPGAD_03575 4.3e-258 S Erythromycin esterase
EFDNPGAD_03576 3.2e-46 ybfN
EFDNPGAD_03577 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
EFDNPGAD_03578 2.7e-85 ybfM S SNARE associated Golgi protein
EFDNPGAD_03579 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EFDNPGAD_03580 2.5e-169 S Alpha/beta hydrolase family
EFDNPGAD_03582 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
EFDNPGAD_03583 1.9e-214 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EFDNPGAD_03584 2.3e-145 msmR K AraC-like ligand binding domain
EFDNPGAD_03585 8.8e-162 ybfH EG EamA-like transporter family
EFDNPGAD_03586 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
EFDNPGAD_03588 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
EFDNPGAD_03589 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
EFDNPGAD_03590 2.9e-35 S Protein of unknown function (DUF2651)
EFDNPGAD_03591 7.3e-258 glpT G -transporter
EFDNPGAD_03592 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
EFDNPGAD_03593 2.3e-290 ybeC E amino acid
EFDNPGAD_03594 4.9e-41 ybyB
EFDNPGAD_03595 1.4e-247 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
EFDNPGAD_03596 2.1e-151 ybxI 3.5.2.6 V beta-lactamase
EFDNPGAD_03597 4.9e-30 ybxH S Family of unknown function (DUF5370)
EFDNPGAD_03598 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
EFDNPGAD_03599 2.4e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
EFDNPGAD_03600 1.5e-217 ybdO S Domain of unknown function (DUF4885)
EFDNPGAD_03601 4.8e-154 ybdN
EFDNPGAD_03602 1.6e-140 KLT Protein tyrosine kinase
EFDNPGAD_03604 1.8e-173 T His Kinase A (phospho-acceptor) domain
EFDNPGAD_03605 1.5e-123 T Transcriptional regulatory protein, C terminal
EFDNPGAD_03606 2.4e-181 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EFDNPGAD_03607 9.6e-79 txn CO Thioredoxin-like
EFDNPGAD_03608 7.8e-91 C HEAT repeats
EFDNPGAD_03609 4e-248 skfF S ABC transporter
EFDNPGAD_03610 1.9e-135 skfE V ABC transporter
EFDNPGAD_03611 1.6e-277 V CAAX protease self-immunity
EFDNPGAD_03612 9.1e-239 J 4Fe-4S single cluster domain
EFDNPGAD_03614 2e-203 ybcL EGP Major facilitator Superfamily
EFDNPGAD_03615 5.1e-50 ybzH K Helix-turn-helix domain
EFDNPGAD_03616 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
EFDNPGAD_03617 3.9e-47
EFDNPGAD_03618 3.7e-96 can 4.2.1.1 P carbonic anhydrase
EFDNPGAD_03619 0.0 ybcC S Belongs to the UPF0753 family
EFDNPGAD_03620 1.5e-278 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
EFDNPGAD_03621 5.1e-101 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EFDNPGAD_03622 1.4e-121 adaA 3.2.2.21 K Transcriptional regulator
EFDNPGAD_03623 2.1e-176 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EFDNPGAD_03624 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EFDNPGAD_03625 9.3e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EFDNPGAD_03626 3e-225 ybbR S protein conserved in bacteria
EFDNPGAD_03627 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EFDNPGAD_03628 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
EFDNPGAD_03629 8.5e-99 sigW K Belongs to the sigma-70 factor family. ECF subfamily
EFDNPGAD_03635 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
EFDNPGAD_03636 6.4e-87 ybbJ J acetyltransferase
EFDNPGAD_03637 2.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EFDNPGAD_03638 1.1e-150 ybbH K transcriptional
EFDNPGAD_03639 9.8e-234 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EFDNPGAD_03640 4e-256 yfeW 3.4.16.4 V Belongs to the UPF0214 family
EFDNPGAD_03641 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
EFDNPGAD_03642 4.4e-241 ybbC 3.2.1.52 S protein conserved in bacteria
EFDNPGAD_03643 5.4e-308 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
EFDNPGAD_03644 7.2e-167 feuA P Iron-uptake system-binding protein
EFDNPGAD_03645 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFDNPGAD_03646 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFDNPGAD_03647 2.2e-142 ybbA S Putative esterase
EFDNPGAD_03648 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
EFDNPGAD_03650 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
EFDNPGAD_03651 7.2e-250 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EFDNPGAD_03652 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
EFDNPGAD_03653 5.7e-140 srfAD Q thioesterase
EFDNPGAD_03654 4.2e-228 EGP Major Facilitator Superfamily
EFDNPGAD_03655 4.9e-91 S YcxB-like protein
EFDNPGAD_03656 7.4e-164 ycxC EG EamA-like transporter family
EFDNPGAD_03657 4.4e-255 ycxD K GntR family transcriptional regulator
EFDNPGAD_03658 5.5e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
EFDNPGAD_03659 4.4e-115 yczE S membrane
EFDNPGAD_03660 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
EFDNPGAD_03661 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
EFDNPGAD_03662 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
EFDNPGAD_03663 4.9e-162 bsdA K LysR substrate binding domain
EFDNPGAD_03664 2e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
EFDNPGAD_03665 1.8e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
EFDNPGAD_03666 4e-39 bsdD 4.1.1.61 S response to toxic substance
EFDNPGAD_03667 1.1e-83 yclD
EFDNPGAD_03668 6.2e-162 yclE 3.4.11.5 S Alpha beta hydrolase
EFDNPGAD_03669 1.5e-267 dtpT E amino acid peptide transporter
EFDNPGAD_03670 2.9e-310 yclG M Pectate lyase superfamily protein
EFDNPGAD_03672 6.8e-282 gerKA EG Spore germination protein
EFDNPGAD_03673 1.3e-232 gerKC S spore germination
EFDNPGAD_03674 9.9e-200 gerKB F Spore germination protein
EFDNPGAD_03675 3.9e-122 yclH P ABC transporter
EFDNPGAD_03676 1.7e-204 yclI V ABC transporter (permease) YclI
EFDNPGAD_03677 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFDNPGAD_03678 1.8e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
EFDNPGAD_03679 5.2e-71 S aspartate phosphatase
EFDNPGAD_03682 7.5e-242 lysC 2.7.2.4 E Belongs to the aspartokinase family
EFDNPGAD_03683 1.6e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFDNPGAD_03684 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFDNPGAD_03685 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
EFDNPGAD_03686 5.5e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
EFDNPGAD_03687 1.4e-251 ycnB EGP Major facilitator Superfamily
EFDNPGAD_03688 6.5e-154 ycnC K Transcriptional regulator
EFDNPGAD_03689 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
EFDNPGAD_03690 1.6e-45 ycnE S Monooxygenase
EFDNPGAD_03691 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
EFDNPGAD_03692 1.3e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EFDNPGAD_03693 4.4e-247 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EFDNPGAD_03694 3.4e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EFDNPGAD_03695 6.1e-149 glcU U Glucose uptake
EFDNPGAD_03696 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EFDNPGAD_03697 1.3e-100 ycnI S protein conserved in bacteria
EFDNPGAD_03698 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
EFDNPGAD_03699 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
EFDNPGAD_03700 7.3e-56
EFDNPGAD_03701 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
EFDNPGAD_03702 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
EFDNPGAD_03703 7.3e-211 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
EFDNPGAD_03704 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
EFDNPGAD_03705 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
EFDNPGAD_03706 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
EFDNPGAD_03707 5e-113 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
EFDNPGAD_03708 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
EFDNPGAD_03710 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
EFDNPGAD_03711 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
EFDNPGAD_03712 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
EFDNPGAD_03713 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
EFDNPGAD_03714 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
EFDNPGAD_03715 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
EFDNPGAD_03716 1.2e-132 kipR K Transcriptional regulator
EFDNPGAD_03717 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
EFDNPGAD_03719 1.4e-49 yczJ S biosynthesis
EFDNPGAD_03720 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
EFDNPGAD_03721 2.8e-176 ydhF S Oxidoreductase
EFDNPGAD_03722 0.0 mtlR K transcriptional regulator, MtlR
EFDNPGAD_03723 1.4e-294 ydaB IQ acyl-CoA ligase
EFDNPGAD_03724 1.1e-99 ydaC Q Methyltransferase domain
EFDNPGAD_03725 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EFDNPGAD_03726 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
EFDNPGAD_03727 5e-104 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EFDNPGAD_03728 6.8e-77 ydaG 1.4.3.5 S general stress protein
EFDNPGAD_03729 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
EFDNPGAD_03730 5.1e-47 ydzA EGP Major facilitator Superfamily
EFDNPGAD_03731 2.5e-74 lrpC K Transcriptional regulator
EFDNPGAD_03732 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EFDNPGAD_03733 1.9e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
EFDNPGAD_03734 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
EFDNPGAD_03735 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
EFDNPGAD_03736 4.5e-233 ydaM M Glycosyl transferase family group 2
EFDNPGAD_03737 0.0 ydaN S Bacterial cellulose synthase subunit
EFDNPGAD_03738 0.0 ydaO E amino acid
EFDNPGAD_03739 4.6e-79 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
EFDNPGAD_03740 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
EFDNPGAD_03741 9.4e-40
EFDNPGAD_03742 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
EFDNPGAD_03744 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
EFDNPGAD_03745 3.8e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
EFDNPGAD_03747 8.9e-59 ydbB G Cupin domain
EFDNPGAD_03748 2.8e-63 ydbC S Domain of unknown function (DUF4937
EFDNPGAD_03749 3.2e-155 ydbD P Catalase
EFDNPGAD_03750 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
EFDNPGAD_03751 2.5e-297 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
EFDNPGAD_03752 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
EFDNPGAD_03753 6.3e-227 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EFDNPGAD_03754 4.4e-181 ydbI S AI-2E family transporter
EFDNPGAD_03755 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
EFDNPGAD_03756 5.5e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EFDNPGAD_03757 2.7e-52 ydbL
EFDNPGAD_03758 3e-220 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
EFDNPGAD_03759 1.1e-18 S Fur-regulated basic protein B
EFDNPGAD_03760 2.2e-07 S Fur-regulated basic protein A
EFDNPGAD_03761 1.9e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EFDNPGAD_03762 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
EFDNPGAD_03763 4.6e-202 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EFDNPGAD_03764 1.9e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EFDNPGAD_03765 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EFDNPGAD_03766 2.1e-82 ydbS S Bacterial PH domain
EFDNPGAD_03767 2.2e-263 ydbT S Membrane
EFDNPGAD_03768 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
EFDNPGAD_03769 2.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EFDNPGAD_03770 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
EFDNPGAD_03771 2.3e-223 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EFDNPGAD_03772 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
EFDNPGAD_03773 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
EFDNPGAD_03774 1.3e-143 rsbR T Positive regulator of sigma-B
EFDNPGAD_03775 5.2e-57 rsbS T antagonist
EFDNPGAD_03776 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
EFDNPGAD_03777 7.1e-189 rsbU 3.1.3.3 KT phosphatase
EFDNPGAD_03778 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
EFDNPGAD_03779 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
EFDNPGAD_03780 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EFDNPGAD_03781 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
EFDNPGAD_03785 1.5e-82 ydcG S EVE domain
EFDNPGAD_03786 1.6e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
EFDNPGAD_03787 0.0 yhgF K COG2183 Transcriptional accessory protein
EFDNPGAD_03788 1.6e-84 ydcK S Belongs to the SprT family
EFDNPGAD_03796 1.9e-211 L Belongs to the 'phage' integrase family
EFDNPGAD_03797 1.3e-90 immA E IrrE N-terminal-like domain
EFDNPGAD_03798 4.3e-62 yvaO K Transcriptional
EFDNPGAD_03799 1.1e-16
EFDNPGAD_03800 8.3e-41
EFDNPGAD_03802 5.1e-63 S Bacterial protein of unknown function (DUF961)
EFDNPGAD_03803 1e-273 ydcQ D Ftsk spoiiie family protein
EFDNPGAD_03804 1.5e-205 nicK L Replication initiation factor
EFDNPGAD_03807 1.2e-32 yddA
EFDNPGAD_03808 1.5e-173 yddB S Conjugative transposon protein TcpC
EFDNPGAD_03809 3e-40 yddC
EFDNPGAD_03810 2.4e-95 yddD S TcpE family
EFDNPGAD_03811 0.0 yddE S AAA-like domain
EFDNPGAD_03812 2e-55 S Domain of unknown function (DUF1874)
EFDNPGAD_03813 0.0 yddG S maturation of SSU-rRNA
EFDNPGAD_03814 2.4e-189 yddH CBM50 M Lysozyme-like
EFDNPGAD_03815 8.7e-87 yddI
EFDNPGAD_03816 4.1e-65 S Domain of unknown function with cystatin-like fold (DUF4467)
EFDNPGAD_03817 9.5e-128 S TIR domain
EFDNPGAD_03818 1.4e-74 S response regulator aspartate phosphatase
EFDNPGAD_03820 6.8e-76
EFDNPGAD_03821 7.2e-69
EFDNPGAD_03822 2.7e-188 luxA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EFDNPGAD_03823 2.4e-71 lrpA K transcriptional
EFDNPGAD_03824 3.9e-78 lrpB K transcriptional
EFDNPGAD_03825 9.6e-100 yddQ 3.5.1.19 Q Isochorismatase family
EFDNPGAD_03826 1.5e-143 yddR S Zn-dependent hydrolases of the beta-lactamase fold
EFDNPGAD_03827 5e-227 ydeG EGP Major facilitator Superfamily
EFDNPGAD_03832 9.3e-116
EFDNPGAD_03833 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EFDNPGAD_03834 6.2e-145 S Phage tail protein
EFDNPGAD_03835 0.0 S Pfam Transposase IS66
EFDNPGAD_03836 6.4e-115
EFDNPGAD_03837 0.0 G Exopolysaccharide biosynthesis protein
EFDNPGAD_03838 6.5e-164
EFDNPGAD_03840 1.6e-186 3.5.1.28 M Ami_2
EFDNPGAD_03841 4.4e-32 bhlA S BhlA holin family
EFDNPGAD_03842 5.5e-40 S SPP1 phage holin
EFDNPGAD_03843 3.4e-74 O protein disulfide oxidoreductase activity
EFDNPGAD_03844 4.1e-242 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EFDNPGAD_03845 1.2e-70 CO cell redox homeostasis
EFDNPGAD_03846 0.0 V Peptidase C39 family
EFDNPGAD_03849 1.9e-239 S impB/mucB/samB family C-terminal domain
EFDNPGAD_03850 5.8e-55 S YolD-like protein
EFDNPGAD_03851 1.3e-37
EFDNPGAD_03853 6.8e-09 S Domain of unknown function (DUF4879)
EFDNPGAD_03854 2.8e-99 J Acetyltransferase (GNAT) domain
EFDNPGAD_03855 3.2e-109 yokK S SMI1 / KNR4 family
EFDNPGAD_03856 1.9e-94 yokJ S SMI1 / KNR4 family (SUKH-1)
EFDNPGAD_03857 1.2e-302 UW nuclease activity
EFDNPGAD_03858 6.7e-92 yokH G SMI1 / KNR4 family
EFDNPGAD_03859 4.1e-203
EFDNPGAD_03860 3.3e-113 yokF 3.1.31.1 L RNA catabolic process
EFDNPGAD_03861 1.1e-83 S Bacterial PH domain
EFDNPGAD_03862 8.4e-156 aacC 2.3.1.81 V aminoglycoside
EFDNPGAD_03865 8.9e-95
EFDNPGAD_03866 1.6e-107
EFDNPGAD_03867 2.7e-307 yokA L Recombinase
EFDNPGAD_03869 3.6e-108 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EFDNPGAD_03870 1.4e-10 K Cro/C1-type HTH DNA-binding domain
EFDNPGAD_03878 1.9e-168 S Calcineurin-like phosphoesterase
EFDNPGAD_03879 5.5e-30 sspB S spore protein
EFDNPGAD_03881 3.7e-159 S Thymidylate synthase
EFDNPGAD_03882 3.1e-38 S Protein of unknown function (DUF1643)
EFDNPGAD_03886 8.9e-83 yosT L Bacterial transcription activator, effector binding domain
EFDNPGAD_03887 2.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
EFDNPGAD_03888 6.1e-38 O Glutaredoxin
EFDNPGAD_03889 2.8e-66 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EFDNPGAD_03890 3.3e-97 L HNH endonuclease
EFDNPGAD_03891 1e-107 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EFDNPGAD_03892 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EFDNPGAD_03893 2.3e-117 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EFDNPGAD_03894 5.1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
EFDNPGAD_03911 1.5e-255 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
EFDNPGAD_03913 1.2e-96 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
EFDNPGAD_03914 5.9e-88 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
EFDNPGAD_03919 9.9e-115 DR0488 S protein conserved in bacteria
EFDNPGAD_03920 0.0 2.7.7.7 L DNA polymerase
EFDNPGAD_03921 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
EFDNPGAD_03922 1.2e-224 L DNA primase activity
EFDNPGAD_03923 3.6e-285 3.6.4.12 J DnaB-like helicase C terminal domain
EFDNPGAD_03924 1.4e-86
EFDNPGAD_03925 7.6e-180 L AAA domain
EFDNPGAD_03926 1.3e-170
EFDNPGAD_03931 0.0 M Parallel beta-helix repeats
EFDNPGAD_03932 7.7e-149 S Pfam:DUF867
EFDNPGAD_03935 1e-130 yoqW S Belongs to the SOS response-associated peptidase family
EFDNPGAD_03936 2.4e-155 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
EFDNPGAD_03937 2.3e-77
EFDNPGAD_03944 1e-44
EFDNPGAD_03946 1.5e-97 S Protein of unknown function (DUF1273)
EFDNPGAD_03948 3e-78 yoqH M LysM domain
EFDNPGAD_03951 8.8e-12 S Protein of unknown function (DUF2815)
EFDNPGAD_03952 6.2e-137 kilA S Phage regulatory protein Rha (Phage_pRha)
EFDNPGAD_03963 1.1e-33 K Transcriptional regulator
EFDNPGAD_03964 2.1e-177
EFDNPGAD_03965 6e-263 S DNA-sulfur modification-associated
EFDNPGAD_03966 6.8e-198 L Belongs to the 'phage' integrase family
EFDNPGAD_03971 6.6e-106
EFDNPGAD_03973 1.2e-86
EFDNPGAD_03974 1.1e-96 S Super-infection exclusion protein B
EFDNPGAD_03979 1.1e-07 ywlA S Uncharacterised protein family (UPF0715)
EFDNPGAD_03980 3.8e-259
EFDNPGAD_03981 4.6e-35 K Cro/C1-type HTH DNA-binding domain
EFDNPGAD_03982 1.4e-256
EFDNPGAD_03984 5.9e-238
EFDNPGAD_03986 4e-17
EFDNPGAD_03987 5.7e-55 bldD K domain, Protein
EFDNPGAD_03990 0.0
EFDNPGAD_03991 1.8e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EFDNPGAD_03993 2.6e-230
EFDNPGAD_03996 1.8e-175
EFDNPGAD_03997 0.0 gp17a S Terminase-like family
EFDNPGAD_03998 6.3e-282
EFDNPGAD_03999 2.1e-266
EFDNPGAD_04000 1.6e-94
EFDNPGAD_04001 5.7e-186
EFDNPGAD_04002 5.1e-81
EFDNPGAD_04003 1.1e-68
EFDNPGAD_04005 1.4e-121
EFDNPGAD_04006 2.6e-91
EFDNPGAD_04007 8.1e-131
EFDNPGAD_04008 1.6e-90
EFDNPGAD_04011 1e-57
EFDNPGAD_04012 1.1e-172
EFDNPGAD_04013 8.1e-07
EFDNPGAD_04014 2.5e-10 xkdX
EFDNPGAD_04015 2.5e-86
EFDNPGAD_04016 6.3e-70
EFDNPGAD_04017 2.1e-193 xerH A Belongs to the 'phage' integrase family
EFDNPGAD_04019 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EFDNPGAD_04020 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EFDNPGAD_04021 1.8e-37 yaaB S Domain of unknown function (DUF370)
EFDNPGAD_04022 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EFDNPGAD_04023 2.4e-33 yaaA S S4 domain
EFDNPGAD_04024 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EFDNPGAD_04025 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EFDNPGAD_04026 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EFDNPGAD_04027 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EFDNPGAD_04028 6.5e-108 jag S single-stranded nucleic acid binding R3H
EFDNPGAD_04029 3.1e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EFDNPGAD_04030 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EFDNPGAD_04031 2.2e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
EFDNPGAD_04032 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
EFDNPGAD_04033 1.5e-74 S Bacterial PH domain
EFDNPGAD_04034 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
EFDNPGAD_04035 2.1e-149 spo0J K Belongs to the ParB family
EFDNPGAD_04036 1.6e-111 yyaC S Sporulation protein YyaC
EFDNPGAD_04037 8.1e-177 yyaD S Membrane
EFDNPGAD_04038 2.3e-33 yyzM S protein conserved in bacteria
EFDNPGAD_04039 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EFDNPGAD_04040 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EFDNPGAD_04041 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
EFDNPGAD_04042 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EFDNPGAD_04043 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EFDNPGAD_04044 8.1e-145 xth 3.1.11.2 L exodeoxyribonuclease III
EFDNPGAD_04045 3.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
EFDNPGAD_04046 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EFDNPGAD_04047 5.1e-96 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
EFDNPGAD_04048 3.8e-246 EGP Major facilitator superfamily
EFDNPGAD_04049 9.5e-169 yyaK S CAAX protease self-immunity
EFDNPGAD_04050 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
EFDNPGAD_04051 3.3e-161 yyaM EG EamA-like transporter family
EFDNPGAD_04052 5.1e-61 yyaN K MerR HTH family regulatory protein
EFDNPGAD_04053 9.7e-44 yyaL O Highly conserved protein containing a thioredoxin domain
EFDNPGAD_04054 1.7e-249 tetL EGP Major facilitator Superfamily
EFDNPGAD_04055 1.7e-107 yyaP 1.5.1.3 H RibD C-terminal domain
EFDNPGAD_04056 5.4e-67 yyaQ S YjbR
EFDNPGAD_04057 5.4e-100 yyaR K Acetyltransferase (GNAT) domain
EFDNPGAD_04058 1.5e-101 yyaS S Membrane
EFDNPGAD_04059 5.9e-79 yjcF S Acetyltransferase (GNAT) domain
EFDNPGAD_04060 5.6e-77 yybA 2.3.1.57 K transcriptional
EFDNPGAD_04061 3e-127 S Metallo-beta-lactamase superfamily
EFDNPGAD_04062 2.7e-77 yybC
EFDNPGAD_04063 2e-79 yjcF S Acetyltransferase (GNAT) domain
EFDNPGAD_04064 2.1e-165 yybE K Transcriptional regulator
EFDNPGAD_04065 3.2e-220 ynfM EGP Major facilitator Superfamily
EFDNPGAD_04066 3e-124 yybG S Pentapeptide repeat-containing protein
EFDNPGAD_04067 5.9e-67 yybH S SnoaL-like domain
EFDNPGAD_04068 6.2e-132
EFDNPGAD_04069 2.6e-115 V ATPases associated with a variety of cellular activities
EFDNPGAD_04070 2e-127 S Protein of unknown function (DUF2705)
EFDNPGAD_04071 9e-122
EFDNPGAD_04072 4.1e-125
EFDNPGAD_04073 1.3e-78 yybN S Protein of unknown function (DUF2712)
EFDNPGAD_04074 1e-16
EFDNPGAD_04075 2.3e-240 yybO G COG0477 Permeases of the major facilitator superfamily
EFDNPGAD_04077 1.3e-70
EFDNPGAD_04078 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
EFDNPGAD_04079 1.4e-68 ydeP3 K Transcriptional regulator
EFDNPGAD_04080 3.9e-84 cotF M Spore coat protein
EFDNPGAD_04082 2.9e-160 yybS S membrane
EFDNPGAD_04083 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
EFDNPGAD_04084 2.2e-73 rplI J binds to the 23S rRNA
EFDNPGAD_04085 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EFDNPGAD_04086 8.4e-221 yeaN P COG2807 Cyanate permease
EFDNPGAD_04087 1.9e-15 yycC K YycC-like protein
EFDNPGAD_04089 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
EFDNPGAD_04090 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
EFDNPGAD_04091 8e-78 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EFDNPGAD_04092 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EFDNPGAD_04097 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFDNPGAD_04098 0.0 vicK 2.7.13.3 T Histidine kinase
EFDNPGAD_04099 3.6e-260 yycH S protein conserved in bacteria
EFDNPGAD_04100 7.3e-155 yycI S protein conserved in bacteria
EFDNPGAD_04101 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
EFDNPGAD_04102 8.4e-221 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EFDNPGAD_04103 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
EFDNPGAD_04104 1.7e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
EFDNPGAD_04105 9.7e-261 rocE E amino acid
EFDNPGAD_04106 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
EFDNPGAD_04108 5e-188 S aspartate phosphatase
EFDNPGAD_04109 3.1e-86 yycN 2.3.1.128 K Acetyltransferase
EFDNPGAD_04110 5.8e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EFDNPGAD_04111 1.6e-221 yycP
EFDNPGAD_04112 2.1e-33 yycQ S Protein of unknown function (DUF2651)
EFDNPGAD_04114 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EFDNPGAD_04115 4.2e-71
EFDNPGAD_04116 1.1e-09 S YyzF-like protein
EFDNPGAD_04117 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EFDNPGAD_04118 7.3e-280 S Calcineurin-like phosphoesterase
EFDNPGAD_04119 3.5e-65
EFDNPGAD_04120 0.0 S Uncharacterised protein conserved in bacteria (DUF2326)
EFDNPGAD_04121 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
EFDNPGAD_04122 8e-12
EFDNPGAD_04123 7.7e-185 S Radical SAM superfamily
EFDNPGAD_04124 8.4e-134 yydH O Peptidase M50
EFDNPGAD_04125 1.8e-110 prrC P ABC transporter
EFDNPGAD_04126 3.3e-119 S ABC-2 family transporter protein
EFDNPGAD_04127 7.6e-13
EFDNPGAD_04128 1.3e-128 yydK K Transcriptional regulator
EFDNPGAD_04129 2.5e-19 bglF G phosphotransferase system
EFDNPGAD_04130 6.4e-292 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EFDNPGAD_04131 3.8e-287 ahpF O Alkyl hydroperoxide reductase
EFDNPGAD_04132 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
EFDNPGAD_04133 3.8e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EFDNPGAD_04134 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
EFDNPGAD_04135 4.6e-304 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
EFDNPGAD_04136 7.3e-127 gntR K transcriptional
EFDNPGAD_04137 7e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
EFDNPGAD_04138 1.3e-193 yxaB GM Polysaccharide pyruvyl transferase
EFDNPGAD_04139 2.6e-118 yxaC M effector of murein hydrolase
EFDNPGAD_04140 5.2e-50 S LrgA family
EFDNPGAD_04141 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
EFDNPGAD_04142 2.3e-201 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EFDNPGAD_04143 7.1e-101 yxaF K Transcriptional regulator
EFDNPGAD_04144 1.5e-199 yxaG 1.13.11.24 S AraC-like ligand binding domain
EFDNPGAD_04145 1.4e-228 P Protein of unknown function (DUF418)
EFDNPGAD_04146 1.1e-75 yxaI S membrane protein domain
EFDNPGAD_04147 3.5e-65 S Family of unknown function (DUF5391)
EFDNPGAD_04148 6.8e-93 S PQQ-like domain
EFDNPGAD_04149 7.6e-214 yxaM U MFS_1 like family
EFDNPGAD_04150 0.0 asnB 6.3.5.4 E Asparagine synthase
EFDNPGAD_04151 1.1e-86 yxnB
EFDNPGAD_04152 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
EFDNPGAD_04153 3.3e-127 yxbB Q Met-10+ like-protein
EFDNPGAD_04155 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
EFDNPGAD_04156 8.7e-30 cspL K Cold shock
EFDNPGAD_04157 6.1e-79 carD K Transcription factor
EFDNPGAD_04158 4.6e-35 ydzE EG spore germination
EFDNPGAD_04159 1.1e-166 rhaS5 K AraC-like ligand binding domain
EFDNPGAD_04160 2.3e-173 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EFDNPGAD_04161 2.5e-166 ydeE K AraC family transcriptional regulator
EFDNPGAD_04162 2.2e-265 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EFDNPGAD_04163 3.4e-220 ydeG EGP Major facilitator superfamily
EFDNPGAD_04164 2.9e-47 ydeH
EFDNPGAD_04165 8.9e-107 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
EFDNPGAD_04166 4e-116
EFDNPGAD_04167 1.8e-153 ydeK EG -transporter
EFDNPGAD_04168 1.5e-274 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EFDNPGAD_04169 4.2e-74 maoC I N-terminal half of MaoC dehydratase
EFDNPGAD_04170 8.6e-107 ydeN S Serine hydrolase
EFDNPGAD_04171 1.1e-58 K HxlR-like helix-turn-helix
EFDNPGAD_04172 1.9e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
EFDNPGAD_04173 4.8e-69 ydeP K Transcriptional regulator
EFDNPGAD_04174 1.6e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
EFDNPGAD_04175 1.2e-195 ydeR EGP Major facilitator Superfamily
EFDNPGAD_04176 8.4e-105 ydeS K Transcriptional regulator
EFDNPGAD_04177 1.3e-57 arsR K transcriptional
EFDNPGAD_04178 5.2e-232 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EFDNPGAD_04179 7.2e-149 ydfB J GNAT acetyltransferase
EFDNPGAD_04180 6.7e-162 ydfC EG EamA-like transporter family
EFDNPGAD_04181 1.9e-275 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EFDNPGAD_04182 5.9e-117 ydfE S Flavin reductase like domain
EFDNPGAD_04183 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
EFDNPGAD_04184 1.5e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EFDNPGAD_04186 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
EFDNPGAD_04187 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EFDNPGAD_04188 0.0 ydfJ S drug exporters of the RND superfamily
EFDNPGAD_04189 1.9e-177 S Alpha/beta hydrolase family
EFDNPGAD_04190 5.9e-118 S Protein of unknown function (DUF554)
EFDNPGAD_04191 3.2e-147 K Bacterial transcription activator, effector binding domain
EFDNPGAD_04192 1.6e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EFDNPGAD_04193 9.6e-112 ydfN C nitroreductase
EFDNPGAD_04194 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
EFDNPGAD_04195 8.8e-63 mhqP S DoxX
EFDNPGAD_04196 1.3e-57 traF CO Thioredoxin
EFDNPGAD_04197 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
EFDNPGAD_04198 6.3e-29
EFDNPGAD_04200 4.4e-118 ydfR S Protein of unknown function (DUF421)
EFDNPGAD_04201 5.2e-122 ydfS S Protein of unknown function (DUF421)
EFDNPGAD_04202 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
EFDNPGAD_04203 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
EFDNPGAD_04204 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
EFDNPGAD_04205 1.5e-101 K Bacterial regulatory proteins, tetR family
EFDNPGAD_04206 7.3e-53 S DoxX-like family
EFDNPGAD_04207 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
EFDNPGAD_04208 4.2e-308 expZ S ABC transporter
EFDNPGAD_04209 4e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
EFDNPGAD_04210 4.6e-91 dinB S DinB family
EFDNPGAD_04211 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
EFDNPGAD_04212 0.0 ydgH S drug exporters of the RND superfamily
EFDNPGAD_04213 1e-113 drgA C nitroreductase
EFDNPGAD_04214 1.1e-69 ydgJ K Winged helix DNA-binding domain
EFDNPGAD_04215 2.5e-209 tcaB EGP Major facilitator Superfamily
EFDNPGAD_04216 1.2e-121 ydhB S membrane transporter protein
EFDNPGAD_04217 6.5e-122 ydhC K FCD
EFDNPGAD_04218 3.3e-244 ydhD M Glycosyl hydrolase
EFDNPGAD_04219 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EFDNPGAD_04220 1.9e-127
EFDNPGAD_04221 1.4e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
EFDNPGAD_04222 4.6e-69 frataxin S Domain of unknown function (DU1801)
EFDNPGAD_04224 4.1e-86 K Acetyltransferase (GNAT) domain
EFDNPGAD_04225 1.8e-184 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
EFDNPGAD_04226 1.7e-99 ydhK M Protein of unknown function (DUF1541)
EFDNPGAD_04227 4.6e-200 pbuE EGP Major facilitator Superfamily
EFDNPGAD_04228 1.1e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
EFDNPGAD_04229 3.5e-52 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
EFDNPGAD_04230 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EFDNPGAD_04231 2.4e-288 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EFDNPGAD_04232 3.9e-133 ydhQ K UTRA
EFDNPGAD_04233 9.2e-172 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
EFDNPGAD_04234 4.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
EFDNPGAD_04235 7.3e-216 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
EFDNPGAD_04236 8.7e-78 ydhU P Catalase
EFDNPGAD_04237 1.1e-16 ydhU P Manganese containing catalase
EFDNPGAD_04240 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
EFDNPGAD_04241 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
EFDNPGAD_04242 1.2e-84 gerD
EFDNPGAD_04243 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
EFDNPGAD_04244 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EFDNPGAD_04245 9.7e-66 ybaK S Protein of unknown function (DUF2521)
EFDNPGAD_04246 8.2e-145 ybaJ Q Methyltransferase domain
EFDNPGAD_04247 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
EFDNPGAD_04248 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EFDNPGAD_04249 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EFDNPGAD_04250 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EFDNPGAD_04251 8.8e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EFDNPGAD_04252 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EFDNPGAD_04253 3.6e-58 rplQ J Ribosomal protein L17
EFDNPGAD_04254 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EFDNPGAD_04255 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EFDNPGAD_04256 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EFDNPGAD_04257 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
EFDNPGAD_04258 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EFDNPGAD_04259 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
EFDNPGAD_04260 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EFDNPGAD_04261 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EFDNPGAD_04262 1.8e-72 rplO J binds to the 23S rRNA
EFDNPGAD_04263 1.9e-23 rpmD J Ribosomal protein L30
EFDNPGAD_04264 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EFDNPGAD_04265 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EFDNPGAD_04266 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EFDNPGAD_04267 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EFDNPGAD_04268 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EFDNPGAD_04269 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EFDNPGAD_04270 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EFDNPGAD_04271 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EFDNPGAD_04272 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EFDNPGAD_04273 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
EFDNPGAD_04274 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EFDNPGAD_04275 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EFDNPGAD_04276 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EFDNPGAD_04277 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EFDNPGAD_04278 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EFDNPGAD_04279 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EFDNPGAD_04280 3e-105 rplD J Forms part of the polypeptide exit tunnel
EFDNPGAD_04281 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EFDNPGAD_04282 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
EFDNPGAD_04283 9.1e-186 ybaC 3.4.11.5 S Alpha/beta hydrolase family
EFDNPGAD_04284 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EFDNPGAD_04285 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EFDNPGAD_04286 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EFDNPGAD_04287 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EFDNPGAD_04288 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
EFDNPGAD_04289 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EFDNPGAD_04290 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EFDNPGAD_04291 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
EFDNPGAD_04292 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EFDNPGAD_04293 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EFDNPGAD_04294 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EFDNPGAD_04295 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EFDNPGAD_04296 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
EFDNPGAD_04297 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EFDNPGAD_04298 4.4e-115 sigH K Belongs to the sigma-70 factor family
EFDNPGAD_04299 1.2e-88 yacP S RNA-binding protein containing a PIN domain
EFDNPGAD_04300 1.2e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EFDNPGAD_04301 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EFDNPGAD_04302 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
EFDNPGAD_04303 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
EFDNPGAD_04304 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EFDNPGAD_04305 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
EFDNPGAD_04306 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
EFDNPGAD_04307 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
EFDNPGAD_04308 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EFDNPGAD_04309 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EFDNPGAD_04310 0.0 clpC O Belongs to the ClpA ClpB family
EFDNPGAD_04311 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
EFDNPGAD_04312 4.7e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
EFDNPGAD_04313 2.9e-76 ctsR K Belongs to the CtsR family
EFDNPGAD_04314 3.4e-31 csfB S Inhibitor of sigma-G Gin
EFDNPGAD_04315 4.7e-103 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
EFDNPGAD_04316 4.5e-203 yaaN P Belongs to the TelA family
EFDNPGAD_04317 1.1e-275 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
EFDNPGAD_04318 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EFDNPGAD_04319 2.2e-54 yaaQ S protein conserved in bacteria
EFDNPGAD_04320 1.5e-71 yaaR S protein conserved in bacteria
EFDNPGAD_04321 2.2e-182 holB 2.7.7.7 L DNA polymerase III
EFDNPGAD_04322 2.1e-146 yaaT S stage 0 sporulation protein
EFDNPGAD_04323 4.8e-31 yabA L Involved in initiation control of chromosome replication
EFDNPGAD_04324 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
EFDNPGAD_04325 1.5e-49 yazA L endonuclease containing a URI domain
EFDNPGAD_04326 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EFDNPGAD_04327 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
EFDNPGAD_04328 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EFDNPGAD_04329 1.8e-144 tatD L hydrolase, TatD
EFDNPGAD_04330 4.3e-194 rpfB GH23 T protein conserved in bacteria
EFDNPGAD_04331 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EFDNPGAD_04332 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EFDNPGAD_04333 3.3e-137 yabG S peptidase
EFDNPGAD_04334 7.8e-39 veg S protein conserved in bacteria
EFDNPGAD_04335 8.3e-27 sspF S DNA topological change
EFDNPGAD_04336 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EFDNPGAD_04337 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
EFDNPGAD_04338 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
EFDNPGAD_04339 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
EFDNPGAD_04340 6.6e-230 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EFDNPGAD_04341 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EFDNPGAD_04342 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EFDNPGAD_04343 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EFDNPGAD_04344 2.4e-39 yabK S Peptide ABC transporter permease
EFDNPGAD_04345 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EFDNPGAD_04346 1.5e-92 spoVT K stage V sporulation protein
EFDNPGAD_04347 2.4e-287 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EFDNPGAD_04348 2.7e-245 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
EFDNPGAD_04349 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
EFDNPGAD_04350 1.5e-49 yabP S Sporulation protein YabP
EFDNPGAD_04351 3.9e-108 yabQ S spore cortex biosynthesis protein
EFDNPGAD_04352 1.1e-44 divIC D Septum formation initiator
EFDNPGAD_04353 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
EFDNPGAD_04356 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
EFDNPGAD_04357 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
EFDNPGAD_04358 6.7e-187 KLT serine threonine protein kinase
EFDNPGAD_04359 3.5e-274 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EFDNPGAD_04360 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
EFDNPGAD_04361 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EFDNPGAD_04362 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EFDNPGAD_04363 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EFDNPGAD_04364 3.1e-153 yacD 5.2.1.8 O peptidyl-prolyl isomerase
EFDNPGAD_04365 8.9e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EFDNPGAD_04366 4.7e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EFDNPGAD_04367 1.5e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
EFDNPGAD_04368 1.6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
EFDNPGAD_04369 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EFDNPGAD_04370 8.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EFDNPGAD_04371 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EFDNPGAD_04372 4.1e-30 yazB K transcriptional
EFDNPGAD_04373 3.7e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EFDNPGAD_04374 1.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
EFDNPGAD_04375 2.7e-182 yaaC S YaaC-like Protein
EFDNPGAD_04376 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
EFDNPGAD_04377 5.2e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EFDNPGAD_04378 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EFDNPGAD_04379 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EFDNPGAD_04380 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EFDNPGAD_04381 1.3e-09
EFDNPGAD_04382 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
EFDNPGAD_04383 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
EFDNPGAD_04384 5.6e-215 yaaH M Glycoside Hydrolase Family
EFDNPGAD_04385 2.4e-98 yaaI Q COG1335 Amidases related to nicotinamidase
EFDNPGAD_04386 1e-84 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EFDNPGAD_04387 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EFDNPGAD_04388 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EFDNPGAD_04389 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EFDNPGAD_04390 7.9e-32 yaaL S Protein of unknown function (DUF2508)
EFDNPGAD_04391 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
EFDNPGAD_04392 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EFDNPGAD_04393 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EFDNPGAD_04394 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EFDNPGAD_04395 1.5e-250 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EFDNPGAD_04396 3.4e-39 S COG NOG14552 non supervised orthologous group
EFDNPGAD_04401 2e-08
EFDNPGAD_04407 2e-08
EFDNPGAD_04412 1.6e-41 yhaK S Belongs to the pirin family
EFDNPGAD_04413 1.7e-38 urtC E Belongs to the binding-protein-dependent transport system permease family
EFDNPGAD_04414 7.6e-18 mcp1 NT chemotaxis protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)