ORF_ID e_value Gene_name EC_number CAZy COGs Description
KEFIEGDI_00001 1e-30 S SMI1 / KNR4 family
KEFIEGDI_00002 3.8e-53 S Immunity protein 50
KEFIEGDI_00003 1.3e-179 A Pre-toxin TG
KEFIEGDI_00004 8.2e-81 S response regulator aspartate phosphatase
KEFIEGDI_00006 4.3e-12 L Helix-turn-helix domain of resolvase
KEFIEGDI_00007 1.6e-140 yhfP 1.1.1.1 C Alcohol dehydrogenase GroES-like domain
KEFIEGDI_00008 1.6e-63 K BetI-type transcriptional repressor, C-terminal
KEFIEGDI_00009 8e-08 cisA2 L Recombinase
KEFIEGDI_00010 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KEFIEGDI_00011 1.6e-35 nucB M Deoxyribonuclease NucA/NucB
KEFIEGDI_00012 1.4e-130 yqeB
KEFIEGDI_00013 3.2e-169 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
KEFIEGDI_00014 8.8e-105 yqeD S SNARE associated Golgi protein
KEFIEGDI_00015 3.9e-131 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KEFIEGDI_00016 2e-140 yqeF E GDSL-like Lipase/Acylhydrolase
KEFIEGDI_00018 5.3e-95 yqeG S hydrolase of the HAD superfamily
KEFIEGDI_00019 1e-212 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KEFIEGDI_00020 1.9e-155 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KEFIEGDI_00021 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
KEFIEGDI_00022 7.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KEFIEGDI_00023 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
KEFIEGDI_00024 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KEFIEGDI_00025 3.6e-137 yqeM Q Methyltransferase
KEFIEGDI_00026 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KEFIEGDI_00027 1.6e-103 wza L COG1555 DNA uptake protein and related DNA-binding proteins
KEFIEGDI_00028 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
KEFIEGDI_00029 0.0 comEC S Competence protein ComEC
KEFIEGDI_00030 4.1e-15 S YqzM-like protein
KEFIEGDI_00031 9.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
KEFIEGDI_00032 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
KEFIEGDI_00033 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KEFIEGDI_00034 7.6e-222 spoIIP M stage II sporulation protein P
KEFIEGDI_00035 2.7e-52 yqxA S Protein of unknown function (DUF3679)
KEFIEGDI_00036 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KEFIEGDI_00037 3.5e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
KEFIEGDI_00038 8e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KEFIEGDI_00039 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KEFIEGDI_00040 0.0 dnaK O Heat shock 70 kDa protein
KEFIEGDI_00041 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KEFIEGDI_00042 5.4e-175 prmA J Methylates ribosomal protein L11
KEFIEGDI_00043 3.6e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KEFIEGDI_00044 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
KEFIEGDI_00045 1.5e-156 yqeW P COG1283 Na phosphate symporter
KEFIEGDI_00046 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KEFIEGDI_00047 1.4e-64 yqeY S Yqey-like protein
KEFIEGDI_00048 2.3e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
KEFIEGDI_00049 6.3e-121 yqfA S UPF0365 protein
KEFIEGDI_00050 1.1e-21 yqfB
KEFIEGDI_00051 2.7e-45 yqfC S sporulation protein YqfC
KEFIEGDI_00052 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
KEFIEGDI_00053 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
KEFIEGDI_00055 0.0 yqfF S membrane-associated HD superfamily hydrolase
KEFIEGDI_00056 8.8e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KEFIEGDI_00057 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KEFIEGDI_00058 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KEFIEGDI_00059 9e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KEFIEGDI_00060 8.4e-19 S YqzL-like protein
KEFIEGDI_00061 6.3e-145 recO L Involved in DNA repair and RecF pathway recombination
KEFIEGDI_00062 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KEFIEGDI_00063 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KEFIEGDI_00064 6.4e-111 ccpN K CBS domain
KEFIEGDI_00065 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KEFIEGDI_00066 4.5e-88 yaiI S Belongs to the UPF0178 family
KEFIEGDI_00067 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KEFIEGDI_00068 4.4e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KEFIEGDI_00069 2.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
KEFIEGDI_00070 5.7e-115 trmK 2.1.1.217 S SAM-dependent methyltransferase
KEFIEGDI_00071 2.2e-207 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KEFIEGDI_00072 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KEFIEGDI_00074 7.2e-242 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KEFIEGDI_00075 2.6e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KEFIEGDI_00076 2.1e-36 yqfT S Protein of unknown function (DUF2624)
KEFIEGDI_00077 1.8e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KEFIEGDI_00078 1.9e-77 zur P Belongs to the Fur family
KEFIEGDI_00079 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
KEFIEGDI_00080 3.7e-61 yqfX S membrane
KEFIEGDI_00081 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KEFIEGDI_00082 4.4e-46 yqfZ M LysM domain
KEFIEGDI_00083 3.9e-131 yqgB S Protein of unknown function (DUF1189)
KEFIEGDI_00084 4e-73 yqgC S protein conserved in bacteria
KEFIEGDI_00085 3.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
KEFIEGDI_00086 1.8e-229 yqgE EGP Major facilitator superfamily
KEFIEGDI_00087 0.0 pbpA 3.4.16.4 M penicillin-binding protein
KEFIEGDI_00088 3.7e-143 pstS P Phosphate
KEFIEGDI_00089 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
KEFIEGDI_00090 4.4e-158 pstA P Phosphate transport system permease
KEFIEGDI_00091 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KEFIEGDI_00092 1.4e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KEFIEGDI_00093 7.3e-72 yqzC S YceG-like family
KEFIEGDI_00094 3.5e-50 yqzD
KEFIEGDI_00096 1.1e-198 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
KEFIEGDI_00097 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KEFIEGDI_00098 1.4e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KEFIEGDI_00099 2.5e-09 yqgO
KEFIEGDI_00100 2e-259 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
KEFIEGDI_00101 2.3e-31 yqgQ S Protein conserved in bacteria
KEFIEGDI_00102 1.5e-180 glcK 2.7.1.2 G Glucokinase
KEFIEGDI_00103 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KEFIEGDI_00104 1.6e-221 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
KEFIEGDI_00105 1.3e-196 yqgU
KEFIEGDI_00106 6.9e-50 yqgV S Thiamine-binding protein
KEFIEGDI_00107 8.9e-23 yqgW S Protein of unknown function (DUF2759)
KEFIEGDI_00108 2.6e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
KEFIEGDI_00109 1.8e-37 yqgY S Protein of unknown function (DUF2626)
KEFIEGDI_00110 1.3e-63 yqgZ 1.20.4.1 P Belongs to the ArsC family
KEFIEGDI_00112 6e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KEFIEGDI_00113 2.8e-219 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KEFIEGDI_00114 5.2e-173 corA P Mg2 transporter protein
KEFIEGDI_00115 1.9e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KEFIEGDI_00116 2.3e-166 comGB NU COG1459 Type II secretory pathway, component PulF
KEFIEGDI_00117 1.4e-47 comGC U Required for transformation and DNA binding
KEFIEGDI_00118 5.7e-63 gspH NU protein transport across the cell outer membrane
KEFIEGDI_00119 1.7e-52 comGE
KEFIEGDI_00120 3.9e-41 comGF U Putative Competence protein ComGF
KEFIEGDI_00121 1.2e-43 S ComG operon protein 7
KEFIEGDI_00122 1.4e-26 yqzE S YqzE-like protein
KEFIEGDI_00123 2.8e-53 yqzG S Protein of unknown function (DUF3889)
KEFIEGDI_00124 1.4e-96 yqxM
KEFIEGDI_00125 1.9e-58 sipW 3.4.21.89 U Signal peptidase
KEFIEGDI_00126 2.5e-141 tasA S Cell division protein FtsN
KEFIEGDI_00127 1e-54 sinR K transcriptional
KEFIEGDI_00128 1.2e-24 sinI S Anti-repressor SinI
KEFIEGDI_00129 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
KEFIEGDI_00130 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KEFIEGDI_00131 5.8e-205 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
KEFIEGDI_00132 4.6e-252 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KEFIEGDI_00133 1.5e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KEFIEGDI_00134 3.3e-62 yqhL P COG0607 Rhodanese-related sulfurtransferase
KEFIEGDI_00135 5.7e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
KEFIEGDI_00136 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
KEFIEGDI_00137 4e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
KEFIEGDI_00138 2.2e-61 yqhP
KEFIEGDI_00139 3.4e-172 yqhQ S Protein of unknown function (DUF1385)
KEFIEGDI_00140 4.3e-92 yqhR S Conserved membrane protein YqhR
KEFIEGDI_00141 1.6e-76 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
KEFIEGDI_00142 7.5e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KEFIEGDI_00143 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KEFIEGDI_00144 1e-36 yqhV S Protein of unknown function (DUF2619)
KEFIEGDI_00145 3e-170 spoIIIAA S stage III sporulation protein AA
KEFIEGDI_00146 1.1e-84 spoIIIAB S Stage III sporulation protein
KEFIEGDI_00147 7.6e-29 spoIIIAC S stage III sporulation protein AC
KEFIEGDI_00148 2.3e-58 spoIIIAD S Stage III sporulation protein AD
KEFIEGDI_00149 2.9e-197 spoIIIAE S stage III sporulation protein AE
KEFIEGDI_00150 1.5e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
KEFIEGDI_00151 8.5e-109 spoIIIAG S stage III sporulation protein AG
KEFIEGDI_00152 9.9e-91 spoIIIAH S SpoIIIAH-like protein
KEFIEGDI_00153 7.2e-117 gatM 2.1.4.1 E amidinotransferase
KEFIEGDI_00154 9.6e-173 V ABC transporter transmembrane region
KEFIEGDI_00155 4.6e-11 yfhR3 S Acetyl xylan esterase (AXE1)
KEFIEGDI_00156 8.8e-16 G phosphotransferase activity, carboxyl group as acceptor
KEFIEGDI_00157 1.4e-62 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KEFIEGDI_00158 4.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KEFIEGDI_00159 3.6e-67 yqhY S protein conserved in bacteria
KEFIEGDI_00160 2.5e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KEFIEGDI_00161 4.3e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KEFIEGDI_00162 3.2e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KEFIEGDI_00163 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KEFIEGDI_00164 2.2e-162 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KEFIEGDI_00165 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KEFIEGDI_00166 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
KEFIEGDI_00167 6.6e-78 argR K Regulates arginine biosynthesis genes
KEFIEGDI_00168 7.1e-306 recN L May be involved in recombinational repair of damaged DNA
KEFIEGDI_00169 8e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
KEFIEGDI_00170 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
KEFIEGDI_00172 4.7e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
KEFIEGDI_00174 1.5e-25
KEFIEGDI_00175 9.7e-101 amiC 3.5.1.28 M Cell wall hydrolase autolysin
KEFIEGDI_00176 6e-129 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KEFIEGDI_00177 1e-218 mmgA 2.3.1.9 I Belongs to the thiolase family
KEFIEGDI_00178 9.8e-155 hbdA 1.1.1.157 I Dehydrogenase
KEFIEGDI_00179 1.5e-211 mmgC I acyl-CoA dehydrogenase
KEFIEGDI_00180 1.7e-204 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
KEFIEGDI_00181 2.4e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
KEFIEGDI_00182 2.5e-161 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KEFIEGDI_00183 8.9e-34 yqzF S Protein of unknown function (DUF2627)
KEFIEGDI_00184 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
KEFIEGDI_00185 5.1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
KEFIEGDI_00186 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
KEFIEGDI_00187 6e-202 buk 2.7.2.7 C Belongs to the acetokinase family
KEFIEGDI_00188 7e-267 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KEFIEGDI_00189 2.7e-185 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KEFIEGDI_00190 1.5e-183 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KEFIEGDI_00191 3.6e-222 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KEFIEGDI_00192 1.4e-150 bmrR K helix_turn_helix, mercury resistance
KEFIEGDI_00193 7.9e-208 norA EGP Major facilitator Superfamily
KEFIEGDI_00194 1.1e-164 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KEFIEGDI_00195 6e-76 yqiW S Belongs to the UPF0403 family
KEFIEGDI_00196 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
KEFIEGDI_00197 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
KEFIEGDI_00198 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KEFIEGDI_00199 2.8e-174 yqjA S Putative aromatic acid exporter C-terminal domain
KEFIEGDI_00200 4.4e-97 yqjB S protein conserved in bacteria
KEFIEGDI_00202 5.6e-71 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
KEFIEGDI_00203 2.3e-60 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KEFIEGDI_00204 1.2e-146 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KEFIEGDI_00205 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
KEFIEGDI_00206 2.1e-39 yqjF S Uncharacterized conserved protein (COG2071)
KEFIEGDI_00208 2.2e-140 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KEFIEGDI_00209 4.5e-24 yqzJ
KEFIEGDI_00210 5.8e-233 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KEFIEGDI_00211 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KEFIEGDI_00212 8.3e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
KEFIEGDI_00213 1.8e-144 spsA M Spore Coat
KEFIEGDI_00214 4.4e-266 spsB M Capsule polysaccharide biosynthesis protein
KEFIEGDI_00215 8.7e-223 spsC E Belongs to the DegT DnrJ EryC1 family
KEFIEGDI_00216 3.7e-162 spsD 2.3.1.210 K Spore Coat
KEFIEGDI_00217 2.7e-213 spsE 2.5.1.56 M acid synthase
KEFIEGDI_00218 3.5e-129 spsF M Spore Coat
KEFIEGDI_00219 2.7e-188 spsG M Spore Coat
KEFIEGDI_00220 2.1e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KEFIEGDI_00221 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KEFIEGDI_00222 2.2e-159 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KEFIEGDI_00223 1.3e-86 spsL 5.1.3.13 M Spore Coat
KEFIEGDI_00224 2.6e-77
KEFIEGDI_00225 2.2e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
KEFIEGDI_00226 4.6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
KEFIEGDI_00227 4.6e-197 rocB E arginine degradation protein
KEFIEGDI_00228 2e-117 rocB E arginine degradation protein
KEFIEGDI_00229 3.1e-248 lysP E amino acid
KEFIEGDI_00230 3.6e-203 ywfA EGP Major facilitator Superfamily
KEFIEGDI_00231 3.3e-233 ywfG 2.6.1.83 E Aminotransferase class I and II
KEFIEGDI_00232 1.5e-122 IQ Enoyl-(Acyl carrier protein) reductase
KEFIEGDI_00233 1.3e-145 ywfI C May function as heme-dependent peroxidase
KEFIEGDI_00234 6.2e-174 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
KEFIEGDI_00235 2.4e-156 cysL K Transcriptional regulator
KEFIEGDI_00236 1.5e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
KEFIEGDI_00237 1.7e-154 ywfM EG EamA-like transporter family
KEFIEGDI_00238 1.8e-107 rsfA_1
KEFIEGDI_00239 3.1e-36 ywzC S Belongs to the UPF0741 family
KEFIEGDI_00240 3.1e-253 ywfO S COG1078 HD superfamily phosphohydrolases
KEFIEGDI_00241 2.7e-88 ywgA 2.1.1.72, 3.1.21.3
KEFIEGDI_00242 2.4e-78 yffB K Transcriptional regulator
KEFIEGDI_00243 3.7e-236 mmr U Major Facilitator Superfamily
KEFIEGDI_00245 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KEFIEGDI_00246 3.3e-71 ywhA K Transcriptional regulator
KEFIEGDI_00247 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
KEFIEGDI_00248 2.5e-118 ywhC S Peptidase family M50
KEFIEGDI_00249 5.8e-94 ywhD S YwhD family
KEFIEGDI_00250 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KEFIEGDI_00251 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KEFIEGDI_00252 2.1e-168 speB 3.5.3.11 E Belongs to the arginase family
KEFIEGDI_00253 2.8e-28 ywhH S Aminoacyl-tRNA editing domain
KEFIEGDI_00255 9.8e-86 S aspartate phosphatase
KEFIEGDI_00256 1.2e-191 ywhK CO amine dehydrogenase activity
KEFIEGDI_00257 9.6e-237 ywhL CO amine dehydrogenase activity
KEFIEGDI_00259 1e-245 L Peptidase, M16
KEFIEGDI_00260 2.2e-213 2.7.1.26, 2.7.7.2 L Peptidase, M16
KEFIEGDI_00261 3.7e-230 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
KEFIEGDI_00262 1.3e-131 cbiO V ABC transporter
KEFIEGDI_00264 6.4e-270 C Fe-S oxidoreductases
KEFIEGDI_00265 1e-07 S Bacteriocin subtilosin A
KEFIEGDI_00266 2.3e-72 ywiB S protein conserved in bacteria
KEFIEGDI_00267 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KEFIEGDI_00269 8.3e-201 L COG3666 Transposase and inactivated derivatives
KEFIEGDI_00270 2.7e-42 ywjC
KEFIEGDI_00271 1.6e-182 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
KEFIEGDI_00272 1.1e-212 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
KEFIEGDI_00273 0.0 fadF C COG0247 Fe-S oxidoreductase
KEFIEGDI_00274 5.3e-209 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
KEFIEGDI_00275 1.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KEFIEGDI_00276 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KEFIEGDI_00277 1.3e-42 L Integrase core domain
KEFIEGDI_00278 1.1e-16 L Integrase core domain
KEFIEGDI_00279 2.5e-11 tnpIS3 L Transposase
KEFIEGDI_00280 1.3e-90 ywjG S Domain of unknown function (DUF2529)
KEFIEGDI_00281 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
KEFIEGDI_00282 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
KEFIEGDI_00283 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KEFIEGDI_00284 9.6e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KEFIEGDI_00285 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
KEFIEGDI_00286 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KEFIEGDI_00287 1.1e-32 rpmE J Binds the 23S rRNA
KEFIEGDI_00288 7e-104 tdk 2.7.1.21 F thymidine kinase
KEFIEGDI_00289 0.0 sfcA 1.1.1.38 C malic enzyme
KEFIEGDI_00290 8.6e-160 ywkB S Membrane transport protein
KEFIEGDI_00291 5.1e-88 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
KEFIEGDI_00292 1.6e-64 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KEFIEGDI_00293 1.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KEFIEGDI_00294 1.9e-158 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KEFIEGDI_00296 2.8e-55 ywlA S Uncharacterised protein family (UPF0715)
KEFIEGDI_00297 6.1e-112 spoIIR S stage II sporulation protein R
KEFIEGDI_00298 2.1e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
KEFIEGDI_00299 1.3e-193 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KEFIEGDI_00300 1.7e-91 mntP P Probably functions as a manganese efflux pump
KEFIEGDI_00301 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KEFIEGDI_00302 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
KEFIEGDI_00303 7.2e-95 ywlG S Belongs to the UPF0340 family
KEFIEGDI_00304 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KEFIEGDI_00305 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KEFIEGDI_00306 2.5e-62 atpI S ATP synthase
KEFIEGDI_00307 3.9e-128 atpB C it plays a direct role in the translocation of protons across the membrane
KEFIEGDI_00308 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KEFIEGDI_00309 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KEFIEGDI_00310 2e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KEFIEGDI_00311 1.7e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KEFIEGDI_00312 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KEFIEGDI_00313 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KEFIEGDI_00314 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KEFIEGDI_00315 4.8e-87 ywmA
KEFIEGDI_00316 1.3e-32 ywzB S membrane
KEFIEGDI_00317 9e-133 ywmB S TATA-box binding
KEFIEGDI_00318 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KEFIEGDI_00319 1.7e-177 spoIID D Stage II sporulation protein D
KEFIEGDI_00320 3.3e-121 ywmC S protein containing a von Willebrand factor type A (vWA) domain
KEFIEGDI_00321 2.7e-120 ywmD S protein containing a von Willebrand factor type A (vWA) domain
KEFIEGDI_00323 9.9e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KEFIEGDI_00324 2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KEFIEGDI_00325 2.1e-104 S response regulator aspartate phosphatase
KEFIEGDI_00326 1.3e-82 ywmF S Peptidase M50
KEFIEGDI_00327 3.8e-11 csbD K CsbD-like
KEFIEGDI_00328 6.9e-218 urtA E Receptor family ligand binding region
KEFIEGDI_00329 9.3e-148 urtB E Belongs to the binding-protein-dependent transport system permease family
KEFIEGDI_00330 1.2e-183 urtC E Belongs to the binding-protein-dependent transport system permease family
KEFIEGDI_00331 6.1e-121 urtD S ATPases associated with a variety of cellular activities
KEFIEGDI_00332 1.4e-111 urtE E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
KEFIEGDI_00333 1.8e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
KEFIEGDI_00334 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
KEFIEGDI_00335 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KEFIEGDI_00336 1.7e-64 ywnA K Transcriptional regulator
KEFIEGDI_00337 5.3e-113 ywnB S NAD(P)H-binding
KEFIEGDI_00338 1.7e-58 ywnC S Family of unknown function (DUF5362)
KEFIEGDI_00339 2.9e-142 mta K transcriptional
KEFIEGDI_00340 4.6e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KEFIEGDI_00341 2.2e-70 ywnF S Family of unknown function (DUF5392)
KEFIEGDI_00342 7.5e-09 ywnC S Family of unknown function (DUF5362)
KEFIEGDI_00343 5.4e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
KEFIEGDI_00344 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
KEFIEGDI_00345 3e-72 ywnJ S VanZ like family
KEFIEGDI_00346 5.9e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
KEFIEGDI_00347 1.6e-58 nrgB K Belongs to the P(II) protein family
KEFIEGDI_00348 4.3e-225 amt P Ammonium transporter
KEFIEGDI_00349 1.9e-76
KEFIEGDI_00350 1.2e-103 phzA Q Isochorismatase family
KEFIEGDI_00351 1.3e-238 ywoD EGP Major facilitator superfamily
KEFIEGDI_00352 4.8e-279 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
KEFIEGDI_00353 2.1e-223 ywoF P Right handed beta helix region
KEFIEGDI_00354 1.1e-209 ywoG EGP Major facilitator Superfamily
KEFIEGDI_00355 2.1e-70 ywoH K COG1846 Transcriptional regulators
KEFIEGDI_00356 3e-44 spoIIID K Stage III sporulation protein D
KEFIEGDI_00357 3.5e-180 mbl D Rod shape-determining protein
KEFIEGDI_00358 8.4e-124 flhO N flagellar basal body
KEFIEGDI_00359 2.9e-140 flhP N flagellar basal body
KEFIEGDI_00360 2.2e-196 S aspartate phosphatase
KEFIEGDI_00361 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KEFIEGDI_00362 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KEFIEGDI_00363 4.9e-146 ywpD T Histidine kinase
KEFIEGDI_00364 5.2e-50 srtA 3.4.22.70 M Sortase family
KEFIEGDI_00365 4e-66 ywpF S YwpF-like protein
KEFIEGDI_00366 3.8e-66 ywpG
KEFIEGDI_00367 8.3e-57 ssbB L Single-stranded DNA-binding protein
KEFIEGDI_00368 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
KEFIEGDI_00369 8e-157 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
KEFIEGDI_00370 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KEFIEGDI_00371 7.8e-307 ywqB S SWIM zinc finger
KEFIEGDI_00372 1.2e-17
KEFIEGDI_00373 4.5e-116 ywqC M biosynthesis protein
KEFIEGDI_00374 2.5e-119 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
KEFIEGDI_00375 3.3e-138 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
KEFIEGDI_00376 3.7e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KEFIEGDI_00377 1.1e-149 ywqG S Domain of unknown function (DUF1963)
KEFIEGDI_00378 3.1e-21 S Domain of unknown function (DUF5082)
KEFIEGDI_00379 3.9e-38 ywqI S Family of unknown function (DUF5344)
KEFIEGDI_00380 1.3e-212 ywqJ S Pre-toxin TG
KEFIEGDI_00381 6.1e-43
KEFIEGDI_00382 5.2e-17
KEFIEGDI_00384 8.5e-72 bdbC O Required for disulfide bond formation in some proteins
KEFIEGDI_00385 1.6e-104 bdbD O Thioredoxin
KEFIEGDI_00386 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
KEFIEGDI_00387 0.0 copA 3.6.3.54 P P-type ATPase
KEFIEGDI_00388 5.9e-29 copZ P Copper resistance protein CopZ
KEFIEGDI_00389 2.2e-48 csoR S transcriptional
KEFIEGDI_00390 4.5e-194 yvaA 1.1.1.371 S Oxidoreductase
KEFIEGDI_00391 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KEFIEGDI_00392 0.0 yvaC S Fusaric acid resistance protein-like
KEFIEGDI_00393 1.3e-72 yvaD S Family of unknown function (DUF5360)
KEFIEGDI_00394 3.4e-53 yvaE P Small Multidrug Resistance protein
KEFIEGDI_00395 2.7e-83 K Bacterial regulatory proteins, tetR family
KEFIEGDI_00396 2e-130 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KEFIEGDI_00398 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KEFIEGDI_00399 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KEFIEGDI_00400 9.6e-143 est 3.1.1.1 S Carboxylesterase
KEFIEGDI_00401 2.4e-23 secG U Preprotein translocase subunit SecG
KEFIEGDI_00402 5.9e-151 yvaM S Serine aminopeptidase, S33
KEFIEGDI_00403 9.8e-36 yvzC K Transcriptional
KEFIEGDI_00404 3.1e-69 K transcriptional
KEFIEGDI_00405 1.2e-68 yvaO K Cro/C1-type HTH DNA-binding domain
KEFIEGDI_00406 2.2e-54 yodB K transcriptional
KEFIEGDI_00407 1.2e-19 NT chemotaxis protein
KEFIEGDI_00408 6.7e-174 NT chemotaxis protein
KEFIEGDI_00409 9.2e-155 T His Kinase A (phosphoacceptor) domain
KEFIEGDI_00410 2.5e-105 K Transcriptional regulatory protein, C terminal
KEFIEGDI_00411 7e-80 mutG S ABC-2 family transporter protein
KEFIEGDI_00412 1.3e-86 spaE S ABC-2 family transporter protein
KEFIEGDI_00413 4.2e-103 mutF V ABC transporter, ATP-binding protein
KEFIEGDI_00415 1.2e-137 spaB S Lantibiotic dehydratase, C terminus
KEFIEGDI_00416 4e-103 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
KEFIEGDI_00417 6.7e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KEFIEGDI_00418 3.6e-109 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
KEFIEGDI_00419 2.2e-210 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KEFIEGDI_00420 3.3e-60 yvbF K Belongs to the GbsR family
KEFIEGDI_00421 1.5e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
KEFIEGDI_00422 6.1e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KEFIEGDI_00423 3.9e-111 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
KEFIEGDI_00424 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KEFIEGDI_00425 1e-96 yvbF K Belongs to the GbsR family
KEFIEGDI_00426 6e-101 yvbG U UPF0056 membrane protein
KEFIEGDI_00427 9.5e-112 yvbH S YvbH-like oligomerisation region
KEFIEGDI_00428 9.1e-119 exoY M Membrane
KEFIEGDI_00429 0.0 tcaA S response to antibiotic
KEFIEGDI_00430 2.8e-76 yvbK 3.1.3.25 K acetyltransferase
KEFIEGDI_00431 1.5e-14 EGP Major facilitator Superfamily
KEFIEGDI_00434 8.1e-09 IQ Alternative locus ID
KEFIEGDI_00435 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KEFIEGDI_00436 2.8e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
KEFIEGDI_00437 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KEFIEGDI_00438 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KEFIEGDI_00439 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KEFIEGDI_00440 9.1e-184 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KEFIEGDI_00441 2.4e-251 araE EGP Major facilitator Superfamily
KEFIEGDI_00442 4.6e-202 araR K transcriptional
KEFIEGDI_00443 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KEFIEGDI_00444 3.7e-157 yvbU K Transcriptional regulator
KEFIEGDI_00445 1.2e-155 yvbV EG EamA-like transporter family
KEFIEGDI_00446 6.9e-240 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
KEFIEGDI_00447 3.3e-169 yvbX S Glycosyl hydrolase
KEFIEGDI_00448 1.2e-129 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KEFIEGDI_00449 2.7e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
KEFIEGDI_00450 2.1e-134 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KEFIEGDI_00451 2.9e-44 S Protein of unknown function (DUF2812)
KEFIEGDI_00452 8.9e-32 K Transcriptional regulator PadR-like family
KEFIEGDI_00453 7.2e-104 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KEFIEGDI_00454 7.4e-44 desK 2.7.13.3 T Histidine kinase
KEFIEGDI_00455 3.8e-133 rsbQ S Alpha/beta hydrolase family
KEFIEGDI_00456 2.7e-159 rsbU 3.1.3.3 T response regulator
KEFIEGDI_00457 5.4e-22 rsbU 3.1.3.3 T response regulator
KEFIEGDI_00458 4.6e-249 galA 3.2.1.89 G arabinogalactan
KEFIEGDI_00459 0.0 lacA 3.2.1.23 G beta-galactosidase
KEFIEGDI_00460 2.1e-149 ganQ P transport
KEFIEGDI_00461 1.1e-231 malC P COG1175 ABC-type sugar transport systems, permease components
KEFIEGDI_00462 1.3e-221 cycB G COG2182 Maltose-binding periplasmic proteins domains
KEFIEGDI_00463 4e-184 lacR K Transcriptional regulator
KEFIEGDI_00464 2.7e-113 yvfI K COG2186 Transcriptional regulators
KEFIEGDI_00465 1.2e-305 yvfH C L-lactate permease
KEFIEGDI_00466 2e-239 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
KEFIEGDI_00467 1e-31 yvfG S YvfG protein
KEFIEGDI_00468 2.2e-187 yvfF GM Exopolysaccharide biosynthesis protein
KEFIEGDI_00469 5.3e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
KEFIEGDI_00470 1.6e-56 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
KEFIEGDI_00471 5.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KEFIEGDI_00472 1.6e-253 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KEFIEGDI_00473 3e-190 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
KEFIEGDI_00474 1.1e-203 epsI GM pyruvyl transferase
KEFIEGDI_00475 6.4e-193 epsH GT2 S Glycosyltransferase like family 2
KEFIEGDI_00476 1.8e-206 epsG S EpsG family
KEFIEGDI_00477 1.9e-217 epsF GT4 M Glycosyl transferases group 1
KEFIEGDI_00478 1.7e-156 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KEFIEGDI_00479 1.7e-218 epsD GT4 M Glycosyl transferase 4-like
KEFIEGDI_00480 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
KEFIEGDI_00481 5.1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
KEFIEGDI_00482 8.9e-122 ywqC M biosynthesis protein
KEFIEGDI_00483 6.3e-76 slr K transcriptional
KEFIEGDI_00484 1.8e-278 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
KEFIEGDI_00486 1.7e-92 padC Q Phenolic acid decarboxylase
KEFIEGDI_00487 1.1e-72 MA20_18690 S Protein of unknown function (DUF3237)
KEFIEGDI_00488 1.3e-122 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KEFIEGDI_00489 6.1e-260 pbpE V Beta-lactamase
KEFIEGDI_00490 3.5e-274 sacB 2.4.1.10 GH68 M levansucrase activity
KEFIEGDI_00491 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
KEFIEGDI_00492 3e-295 yveA E amino acid
KEFIEGDI_00493 7.4e-106 yvdT K Transcriptional regulator
KEFIEGDI_00494 1.5e-50 ykkC P Small Multidrug Resistance protein
KEFIEGDI_00495 4.6e-49 sugE P Small Multidrug Resistance protein
KEFIEGDI_00496 1.3e-72 yvdQ S Protein of unknown function (DUF3231)
KEFIEGDI_00498 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KEFIEGDI_00499 1.3e-114 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
KEFIEGDI_00500 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
KEFIEGDI_00501 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
KEFIEGDI_00502 1e-154 malA S Protein of unknown function (DUF1189)
KEFIEGDI_00503 2.5e-147 malD P transport
KEFIEGDI_00504 1.9e-242 malC P COG1175 ABC-type sugar transport systems, permease components
KEFIEGDI_00505 5.3e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
KEFIEGDI_00506 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
KEFIEGDI_00507 6.1e-174 yvdE K Transcriptional regulator
KEFIEGDI_00508 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
KEFIEGDI_00509 7.7e-29 yvdC S MazG nucleotide pyrophosphohydrolase domain
KEFIEGDI_00510 2.8e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
KEFIEGDI_00511 1.1e-104 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
KEFIEGDI_00512 5.6e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KEFIEGDI_00513 0.0 yxdM V ABC transporter (permease)
KEFIEGDI_00514 5.6e-141 yvcR V ABC transporter, ATP-binding protein
KEFIEGDI_00515 7.5e-197 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
KEFIEGDI_00516 9.6e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEFIEGDI_00517 8.8e-33
KEFIEGDI_00518 1.4e-141 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
KEFIEGDI_00519 1.6e-36 crh G Phosphocarrier protein Chr
KEFIEGDI_00520 4.1e-170 whiA K May be required for sporulation
KEFIEGDI_00521 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KEFIEGDI_00522 5.7e-166 rapZ S Displays ATPase and GTPase activities
KEFIEGDI_00523 3.9e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KEFIEGDI_00524 9.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KEFIEGDI_00525 1.1e-97 usp CBM50 M protein conserved in bacteria
KEFIEGDI_00526 5e-276 S COG0457 FOG TPR repeat
KEFIEGDI_00527 0.0 msbA2 3.6.3.44 V ABC transporter
KEFIEGDI_00529 0.0
KEFIEGDI_00530 5.4e-66
KEFIEGDI_00531 2.8e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
KEFIEGDI_00532 8.1e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KEFIEGDI_00533 1.4e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KEFIEGDI_00534 4.3e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KEFIEGDI_00535 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
KEFIEGDI_00536 2e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KEFIEGDI_00537 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KEFIEGDI_00538 2e-219 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KEFIEGDI_00539 1.1e-138 yvpB NU protein conserved in bacteria
KEFIEGDI_00540 1.3e-119 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
KEFIEGDI_00541 3.4e-158 ytbE S reductase
KEFIEGDI_00542 3.3e-201 ytbD EGP Major facilitator Superfamily
KEFIEGDI_00543 5.7e-58 ytcD K Transcriptional regulator
KEFIEGDI_00544 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KEFIEGDI_00545 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KEFIEGDI_00546 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KEFIEGDI_00547 8.5e-265 dnaB L Membrane attachment protein
KEFIEGDI_00548 6.6e-173 dnaI L Primosomal protein DnaI
KEFIEGDI_00549 1.9e-107 ytxB S SNARE associated Golgi protein
KEFIEGDI_00550 1.6e-157 ytxC S YtxC-like family
KEFIEGDI_00552 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KEFIEGDI_00553 1.1e-147 ysaA S HAD-hyrolase-like
KEFIEGDI_00554 0.0 lytS 2.7.13.3 T Histidine kinase
KEFIEGDI_00555 7e-130 lytT T COG3279 Response regulator of the LytR AlgR family
KEFIEGDI_00556 1.6e-47 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KEFIEGDI_00557 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KEFIEGDI_00560 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KEFIEGDI_00561 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KEFIEGDI_00562 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KEFIEGDI_00563 1.4e-43 ysdA S Membrane
KEFIEGDI_00564 9.2e-68 ysdB S Sigma-w pathway protein YsdB
KEFIEGDI_00565 5.4e-203 ysdC G COG1363 Cellulase M and related proteins
KEFIEGDI_00566 7.1e-186 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
KEFIEGDI_00567 1.7e-292 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
KEFIEGDI_00568 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
KEFIEGDI_00569 3.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
KEFIEGDI_00570 1.3e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
KEFIEGDI_00571 2.4e-220 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
KEFIEGDI_00572 3.2e-250 araN G carbohydrate transport
KEFIEGDI_00573 6e-166 araP G carbohydrate transport
KEFIEGDI_00574 2.9e-143 araQ G transport system permease
KEFIEGDI_00575 2.3e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
KEFIEGDI_00576 0.0 cstA T Carbon starvation protein
KEFIEGDI_00577 3.6e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
KEFIEGDI_00578 4.1e-253 glcF C Glycolate oxidase
KEFIEGDI_00579 5.9e-258 glcD 1.1.3.15 C Glycolate oxidase subunit
KEFIEGDI_00580 2.4e-206 ysfB KT regulator
KEFIEGDI_00581 2.6e-32 sspI S Belongs to the SspI family
KEFIEGDI_00582 1.7e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KEFIEGDI_00583 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KEFIEGDI_00584 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KEFIEGDI_00585 4.4e-106 L Integrase core domain
KEFIEGDI_00586 3e-36 L transposase activity
KEFIEGDI_00587 2.4e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KEFIEGDI_00588 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KEFIEGDI_00589 1.7e-85 cvpA S membrane protein, required for colicin V production
KEFIEGDI_00590 0.0 polX L COG1796 DNA polymerase IV (family X)
KEFIEGDI_00591 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KEFIEGDI_00592 7.3e-68 yshE S membrane
KEFIEGDI_00593 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KEFIEGDI_00594 4e-99 fadR K Transcriptional regulator
KEFIEGDI_00595 2.3e-134 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KEFIEGDI_00596 3.8e-134 etfB C Electron transfer flavoprotein
KEFIEGDI_00597 5.1e-176 etfA C Electron transfer flavoprotein
KEFIEGDI_00598 2e-301 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
KEFIEGDI_00599 2e-52 trxA O Belongs to the thioredoxin family
KEFIEGDI_00600 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KEFIEGDI_00601 3.1e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KEFIEGDI_00602 1.2e-79 yslB S Protein of unknown function (DUF2507)
KEFIEGDI_00603 2.4e-107 sdhC C succinate dehydrogenase
KEFIEGDI_00604 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KEFIEGDI_00605 1.9e-146 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KEFIEGDI_00606 7.2e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
KEFIEGDI_00607 4.4e-30 gerE K Transcriptional regulator
KEFIEGDI_00608 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
KEFIEGDI_00609 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KEFIEGDI_00610 1.2e-189 gerM S COG5401 Spore germination protein
KEFIEGDI_00611 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KEFIEGDI_00612 2.2e-102 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KEFIEGDI_00613 1e-90 ysnB S Phosphoesterase
KEFIEGDI_00615 2.3e-129 ysnF S protein conserved in bacteria
KEFIEGDI_00616 6.2e-76 ysnE K acetyltransferase
KEFIEGDI_00618 0.0 ilvB 2.2.1.6 E Acetolactate synthase
KEFIEGDI_00619 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
KEFIEGDI_00620 4.5e-191 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KEFIEGDI_00621 1e-287 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KEFIEGDI_00622 5.3e-198 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KEFIEGDI_00623 4.8e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KEFIEGDI_00624 4e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KEFIEGDI_00625 3.6e-185 ysoA H Tetratricopeptide repeat
KEFIEGDI_00626 3.5e-225 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KEFIEGDI_00627 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KEFIEGDI_00628 9.2e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
KEFIEGDI_00629 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KEFIEGDI_00630 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
KEFIEGDI_00631 1.4e-89 ysxD
KEFIEGDI_00632 1e-246 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KEFIEGDI_00633 1e-145 hemX O cytochrome C
KEFIEGDI_00634 3e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
KEFIEGDI_00635 1.3e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KEFIEGDI_00636 8.1e-182 hemB 4.2.1.24 H Belongs to the ALAD family
KEFIEGDI_00637 1.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KEFIEGDI_00638 9.3e-206 spoVID M stage VI sporulation protein D
KEFIEGDI_00639 6.6e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KEFIEGDI_00640 1.6e-25
KEFIEGDI_00641 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KEFIEGDI_00642 4.7e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KEFIEGDI_00643 2.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
KEFIEGDI_00644 4e-160 spoIIB S Sporulation related domain
KEFIEGDI_00645 2.8e-102 maf D septum formation protein Maf
KEFIEGDI_00646 1e-125 radC E Belongs to the UPF0758 family
KEFIEGDI_00647 1.8e-184 mreB D Rod shape-determining protein MreB
KEFIEGDI_00648 5.2e-156 mreC M Involved in formation and maintenance of cell shape
KEFIEGDI_00649 1.4e-84 mreD M shape-determining protein
KEFIEGDI_00650 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KEFIEGDI_00651 4.7e-143 minD D Belongs to the ParA family
KEFIEGDI_00652 4.6e-143 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
KEFIEGDI_00653 1.6e-160 spoIVFB S Stage IV sporulation protein
KEFIEGDI_00654 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
KEFIEGDI_00655 4.1e-56 ysxB J ribosomal protein
KEFIEGDI_00656 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KEFIEGDI_00657 7.4e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
KEFIEGDI_00658 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KEFIEGDI_00659 2.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
KEFIEGDI_00660 2.2e-162 pheA 4.2.1.51 E Prephenate dehydratase
KEFIEGDI_00661 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
KEFIEGDI_00662 5.4e-228 nifS 2.8.1.7 E Cysteine desulfurase
KEFIEGDI_00663 3.2e-300 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
KEFIEGDI_00664 6.8e-156 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
KEFIEGDI_00665 1.2e-213 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KEFIEGDI_00666 3.8e-154 safA M spore coat assembly protein SafA
KEFIEGDI_00667 2.3e-46 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KEFIEGDI_00668 3.6e-126 yebC K transcriptional regulatory protein
KEFIEGDI_00669 4.5e-261 alsT E Sodium alanine symporter
KEFIEGDI_00670 4e-51 S Family of unknown function (DUF5412)
KEFIEGDI_00672 1.9e-118 yrzF T serine threonine protein kinase
KEFIEGDI_00673 4.8e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
KEFIEGDI_00674 8.5e-251 csbX EGP Major facilitator Superfamily
KEFIEGDI_00675 2.4e-92 bofC S BofC C-terminal domain
KEFIEGDI_00676 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KEFIEGDI_00677 1.9e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KEFIEGDI_00678 2.6e-18 yrzS S Protein of unknown function (DUF2905)
KEFIEGDI_00679 5.7e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KEFIEGDI_00680 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KEFIEGDI_00681 1.1e-38 yajC U Preprotein translocase subunit YajC
KEFIEGDI_00682 8.4e-73 yrzE S Protein of unknown function (DUF3792)
KEFIEGDI_00683 7.8e-112 yrbG S membrane
KEFIEGDI_00684 4.1e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KEFIEGDI_00685 3.6e-48 yrzD S Post-transcriptional regulator
KEFIEGDI_00686 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KEFIEGDI_00687 3.3e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
KEFIEGDI_00688 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
KEFIEGDI_00689 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KEFIEGDI_00690 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KEFIEGDI_00691 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KEFIEGDI_00692 1.1e-69 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KEFIEGDI_00693 7.5e-15 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KEFIEGDI_00694 7.6e-89 ywrA P COG2059 Chromate transport protein ChrA
KEFIEGDI_00695 1.2e-103 ywrB P Chromate transporter
KEFIEGDI_00696 8e-82 ywrC K Transcriptional regulator
KEFIEGDI_00697 3.3e-302 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KEFIEGDI_00698 2.7e-52 S Domain of unknown function (DUF4181)
KEFIEGDI_00699 3.4e-109 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KEFIEGDI_00700 3.7e-12
KEFIEGDI_00701 3.5e-210 cotH M Spore Coat
KEFIEGDI_00702 7.1e-131 cotB
KEFIEGDI_00703 4.5e-123 ywrJ
KEFIEGDI_00704 1.6e-219 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KEFIEGDI_00705 1.1e-169 alsR K LysR substrate binding domain
KEFIEGDI_00706 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KEFIEGDI_00707 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
KEFIEGDI_00708 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
KEFIEGDI_00709 8e-48 ywsA S Protein of unknown function (DUF3892)
KEFIEGDI_00710 1.9e-83 batE T Sh3 type 3 domain protein
KEFIEGDI_00711 2.9e-157 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
KEFIEGDI_00712 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
KEFIEGDI_00713 9.6e-189 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
KEFIEGDI_00714 2.5e-74 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
KEFIEGDI_00715 3.4e-62 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KEFIEGDI_00716 1.9e-161 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KEFIEGDI_00717 1.8e-176 rbsR K transcriptional
KEFIEGDI_00718 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
KEFIEGDI_00719 8.6e-70 pgsC S biosynthesis protein
KEFIEGDI_00720 8.2e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
KEFIEGDI_00721 3.6e-21 ywtC
KEFIEGDI_00722 7.7e-239 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KEFIEGDI_00723 1.9e-158 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
KEFIEGDI_00724 2.4e-170 ywtF K Transcriptional regulator
KEFIEGDI_00725 2.5e-245 ywtG EGP Major facilitator Superfamily
KEFIEGDI_00726 1.4e-206 gerAC S Spore germination protein
KEFIEGDI_00727 4.8e-126 gerBB E Spore germination protein
KEFIEGDI_00728 3e-179 gerBA EG Spore germination protein
KEFIEGDI_00729 4.3e-22 gerBA EG Spore germination protein
KEFIEGDI_00730 4.3e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
KEFIEGDI_00731 7.5e-214 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KEFIEGDI_00732 2.5e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KEFIEGDI_00733 4.3e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KEFIEGDI_00734 8.1e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
KEFIEGDI_00735 2.6e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
KEFIEGDI_00736 6e-95 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KEFIEGDI_00737 7.1e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KEFIEGDI_00738 9.5e-57 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
KEFIEGDI_00739 1.1e-145 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KEFIEGDI_00740 2.2e-89 ggaA M Glycosyltransferase like family 2
KEFIEGDI_00741 4.8e-208 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KEFIEGDI_00742 2.7e-55
KEFIEGDI_00744 3.5e-08
KEFIEGDI_00745 8.5e-132 tagG GM Transport permease protein
KEFIEGDI_00746 1.6e-275 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KEFIEGDI_00747 1.7e-162 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KEFIEGDI_00748 1.1e-22 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
KEFIEGDI_00749 1.6e-99 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
KEFIEGDI_00750 1.7e-87 M Glycosyltransferase like family 2
KEFIEGDI_00751 3.8e-215 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KEFIEGDI_00752 9.1e-159 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
KEFIEGDI_00753 1e-11
KEFIEGDI_00754 0.0 lytB 3.5.1.28 D Stage II sporulation protein
KEFIEGDI_00755 3.5e-208 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KEFIEGDI_00756 1.7e-95 M Glycosyltransferase like family 2
KEFIEGDI_00757 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KEFIEGDI_00758 9.7e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KEFIEGDI_00759 3.8e-218 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
KEFIEGDI_00760 4.5e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KEFIEGDI_00761 1.2e-261 tuaE M Teichuronic acid biosynthesis protein
KEFIEGDI_00762 3.9e-114 tuaF M protein involved in exopolysaccharide biosynthesis
KEFIEGDI_00763 6.2e-145 tuaG GT2 M Glycosyltransferase like family 2
KEFIEGDI_00764 4.7e-232 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
KEFIEGDI_00765 1.3e-180 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
KEFIEGDI_00766 7.8e-163 yvhJ K Transcriptional regulator
KEFIEGDI_00767 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
KEFIEGDI_00768 1.5e-182 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
KEFIEGDI_00769 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KEFIEGDI_00770 1.1e-153 degV S protein conserved in bacteria
KEFIEGDI_00771 1.9e-261 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KEFIEGDI_00772 2.5e-09 comFB S Late competence development protein ComFB
KEFIEGDI_00773 4.8e-123 comFC S Phosphoribosyl transferase domain
KEFIEGDI_00774 1.7e-72 yvyF S flagellar protein
KEFIEGDI_00775 8e-39 flgM KNU Negative regulator of flagellin synthesis
KEFIEGDI_00776 2.4e-78 flgN NOU FlgN protein
KEFIEGDI_00777 1.2e-264 flgK N flagellar hook-associated protein
KEFIEGDI_00778 7.8e-155 flgL N Belongs to the bacterial flagellin family
KEFIEGDI_00779 2.8e-49 yviE
KEFIEGDI_00780 8e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KEFIEGDI_00781 3.7e-29 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KEFIEGDI_00782 5.9e-93 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KEFIEGDI_00783 1.2e-52 flaG N flagellar protein FlaG
KEFIEGDI_00784 7.7e-248 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KEFIEGDI_00785 4.2e-68 fliS N flagellar protein FliS
KEFIEGDI_00786 1.9e-08 fliT S bacterial-type flagellum organization
KEFIEGDI_00787 4.6e-51
KEFIEGDI_00788 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KEFIEGDI_00789 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KEFIEGDI_00790 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KEFIEGDI_00791 9.3e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
KEFIEGDI_00792 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
KEFIEGDI_00793 6e-123 ftsE D cell division ATP-binding protein FtsE
KEFIEGDI_00794 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KEFIEGDI_00795 1.5e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
KEFIEGDI_00796 5.3e-56 swrA S Swarming motility protein
KEFIEGDI_00797 3.5e-219 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KEFIEGDI_00798 9.6e-226 yvkA EGP Major facilitator Superfamily
KEFIEGDI_00799 2e-100 yvkB K Transcriptional regulator
KEFIEGDI_00800 0.0 yvkC 2.7.9.2 GT Phosphotransferase
KEFIEGDI_00801 1.2e-30 csbA S protein conserved in bacteria
KEFIEGDI_00802 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KEFIEGDI_00803 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KEFIEGDI_00804 1.2e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KEFIEGDI_00805 4.1e-13 yvkN
KEFIEGDI_00806 1.7e-167 yvlB S Putative adhesin
KEFIEGDI_00807 2.6e-26 pspB KT PspC domain
KEFIEGDI_00808 1.2e-50 yvlD S Membrane
KEFIEGDI_00809 1.7e-197 yvmA EGP Major facilitator Superfamily
KEFIEGDI_00810 1.5e-86 yvmB K helix_turn_helix multiple antibiotic resistance protein
KEFIEGDI_00811 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
KEFIEGDI_00812 1.1e-133 yvoA K transcriptional
KEFIEGDI_00813 1.5e-127 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KEFIEGDI_00814 3.2e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KEFIEGDI_00815 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KEFIEGDI_00816 2.4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KEFIEGDI_00817 1.2e-161 yvoD P COG0370 Fe2 transport system protein B
KEFIEGDI_00818 1.9e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
KEFIEGDI_00819 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
KEFIEGDI_00820 4.2e-164 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
KEFIEGDI_00821 1.6e-163 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KEFIEGDI_00822 4.4e-189 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
KEFIEGDI_00823 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KEFIEGDI_00824 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
KEFIEGDI_00825 1.2e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
KEFIEGDI_00826 6.3e-165 ctaG S cytochrome c oxidase
KEFIEGDI_00827 3.5e-61 ylbA S YugN-like family
KEFIEGDI_00828 2.6e-74 ylbB T COG0517 FOG CBS domain
KEFIEGDI_00829 9.6e-200 ylbC S protein with SCP PR1 domains
KEFIEGDI_00830 4.1e-63 ylbD S Putative coat protein
KEFIEGDI_00831 6.7e-37 ylbE S YlbE-like protein
KEFIEGDI_00832 1.8e-75 ylbF S Belongs to the UPF0342 family
KEFIEGDI_00833 7.5e-39 ylbG S UPF0298 protein
KEFIEGDI_00834 2.1e-97 rsmD 2.1.1.171 L Methyltransferase
KEFIEGDI_00835 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KEFIEGDI_00836 1.6e-219 ylbJ S Sporulation integral membrane protein YlbJ
KEFIEGDI_00837 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
KEFIEGDI_00838 6.8e-187 ylbL T Belongs to the peptidase S16 family
KEFIEGDI_00839 2.1e-227 ylbM S Belongs to the UPF0348 family
KEFIEGDI_00841 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
KEFIEGDI_00842 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KEFIEGDI_00843 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
KEFIEGDI_00844 1.5e-88 ylbP K n-acetyltransferase
KEFIEGDI_00845 4.9e-165 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KEFIEGDI_00846 3e-306 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KEFIEGDI_00847 2.9e-78 mraZ K Belongs to the MraZ family
KEFIEGDI_00848 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KEFIEGDI_00849 3.7e-44 ftsL D Essential cell division protein
KEFIEGDI_00850 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
KEFIEGDI_00851 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
KEFIEGDI_00852 1.2e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KEFIEGDI_00853 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KEFIEGDI_00854 3.8e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KEFIEGDI_00855 5.7e-186 spoVE D Belongs to the SEDS family
KEFIEGDI_00856 1.6e-199 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KEFIEGDI_00857 5.3e-167 murB 1.3.1.98 M cell wall formation
KEFIEGDI_00858 4.9e-137 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KEFIEGDI_00859 5.6e-100 ylxW S protein conserved in bacteria
KEFIEGDI_00860 6.6e-102 ylxX S protein conserved in bacteria
KEFIEGDI_00861 6.2e-58 sbp S small basic protein
KEFIEGDI_00862 1.2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KEFIEGDI_00863 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KEFIEGDI_00864 0.0 bpr O COG1404 Subtilisin-like serine proteases
KEFIEGDI_00865 4.8e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
KEFIEGDI_00866 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KEFIEGDI_00867 4e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KEFIEGDI_00868 3.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
KEFIEGDI_00869 2e-249 argE 3.5.1.16 E Acetylornithine deacetylase
KEFIEGDI_00870 2.4e-37 ylmC S sporulation protein
KEFIEGDI_00871 7e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
KEFIEGDI_00872 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KEFIEGDI_00873 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KEFIEGDI_00874 1.6e-39 yggT S membrane
KEFIEGDI_00875 9.7e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
KEFIEGDI_00876 2.6e-67 divIVA D Cell division initiation protein
KEFIEGDI_00877 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KEFIEGDI_00878 6.5e-63 dksA T COG1734 DnaK suppressor protein
KEFIEGDI_00879 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KEFIEGDI_00880 3.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KEFIEGDI_00881 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KEFIEGDI_00882 2.6e-231 pyrP F Xanthine uracil
KEFIEGDI_00883 1e-165 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KEFIEGDI_00884 1.2e-249 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KEFIEGDI_00885 6.5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KEFIEGDI_00886 0.0 carB 6.3.5.5 F Belongs to the CarB family
KEFIEGDI_00887 5e-142 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KEFIEGDI_00888 2.7e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KEFIEGDI_00889 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KEFIEGDI_00890 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KEFIEGDI_00891 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
KEFIEGDI_00892 9.2e-179 cysP P phosphate transporter
KEFIEGDI_00893 5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
KEFIEGDI_00894 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
KEFIEGDI_00895 2.4e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
KEFIEGDI_00896 1.6e-143 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
KEFIEGDI_00897 4.8e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
KEFIEGDI_00898 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
KEFIEGDI_00899 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
KEFIEGDI_00900 6.9e-156 yloC S stress-induced protein
KEFIEGDI_00901 1.5e-40 ylzA S Belongs to the UPF0296 family
KEFIEGDI_00902 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KEFIEGDI_00903 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KEFIEGDI_00904 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KEFIEGDI_00905 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KEFIEGDI_00906 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KEFIEGDI_00907 6.7e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KEFIEGDI_00908 5.4e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KEFIEGDI_00909 2e-205 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KEFIEGDI_00910 6.7e-139 stp 3.1.3.16 T phosphatase
KEFIEGDI_00911 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
KEFIEGDI_00912 4.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KEFIEGDI_00913 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KEFIEGDI_00914 2.6e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
KEFIEGDI_00915 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KEFIEGDI_00916 5.5e-59 asp S protein conserved in bacteria
KEFIEGDI_00917 5.6e-300 yloV S kinase related to dihydroxyacetone kinase
KEFIEGDI_00918 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
KEFIEGDI_00919 1.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
KEFIEGDI_00920 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KEFIEGDI_00921 1.5e-79 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
KEFIEGDI_00922 8.1e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KEFIEGDI_00923 8.5e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KEFIEGDI_00924 5.1e-128 IQ reductase
KEFIEGDI_00925 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KEFIEGDI_00926 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KEFIEGDI_00927 0.0 smc D Required for chromosome condensation and partitioning
KEFIEGDI_00928 2.6e-175 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KEFIEGDI_00929 4.3e-96 S Phosphotransferase enzyme family
KEFIEGDI_00930 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KEFIEGDI_00931 2.3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KEFIEGDI_00932 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KEFIEGDI_00933 4.5e-36 ylqC S Belongs to the UPF0109 family
KEFIEGDI_00934 1.8e-60 ylqD S YlqD protein
KEFIEGDI_00935 1.5e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KEFIEGDI_00936 3.5e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KEFIEGDI_00937 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KEFIEGDI_00938 1.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KEFIEGDI_00939 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KEFIEGDI_00940 1.6e-281 ylqG
KEFIEGDI_00941 8.7e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
KEFIEGDI_00942 4.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KEFIEGDI_00943 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KEFIEGDI_00944 6.8e-167 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
KEFIEGDI_00945 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KEFIEGDI_00946 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KEFIEGDI_00947 2.5e-169 xerC L tyrosine recombinase XerC
KEFIEGDI_00948 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KEFIEGDI_00949 5.7e-245 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KEFIEGDI_00950 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KEFIEGDI_00951 8.1e-38 sumf2 2.1.1.295 GT2,GT4 H N-terminal domain of galactosyltransferase
KEFIEGDI_00952 1.1e-160 sumf2 2.1.1.295 GT2,GT4 H N-terminal domain of galactosyltransferase
KEFIEGDI_00953 1.5e-192 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KEFIEGDI_00954 6.1e-43 H Methionine biosynthesis protein MetW
KEFIEGDI_00955 4.6e-46 H Methionine biosynthesis protein MetW
KEFIEGDI_00956 2.7e-13 M PFAM Glycosyl transferase family 2
KEFIEGDI_00957 2.9e-60 M Glycosyltransferase like family
KEFIEGDI_00958 9.3e-70 Q Collagen triple helix repeat (20 copies)
KEFIEGDI_00959 3.8e-31
KEFIEGDI_00960 3.8e-07
KEFIEGDI_00961 1e-259 glnA 6.3.1.2 E glutamine synthetase
KEFIEGDI_00962 1.1e-68 glnR K transcriptional
KEFIEGDI_00963 7.4e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
KEFIEGDI_00964 5.1e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KEFIEGDI_00965 1.7e-176 spoVK O stage V sporulation protein K
KEFIEGDI_00966 2.8e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KEFIEGDI_00967 2.2e-108 ymaB
KEFIEGDI_00968 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KEFIEGDI_00969 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KEFIEGDI_00970 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
KEFIEGDI_00971 4.5e-22 ymzA
KEFIEGDI_00972 8.2e-23
KEFIEGDI_00973 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
KEFIEGDI_00974 6e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KEFIEGDI_00975 8.6e-45 ymaF S YmaF family
KEFIEGDI_00976 3.9e-44 ebrA P Small Multidrug Resistance protein
KEFIEGDI_00977 6.8e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
KEFIEGDI_00978 3.9e-78 ymaD O redox protein, regulator of disulfide bond formation
KEFIEGDI_00979 2.1e-126 ymaC S Replication protein
KEFIEGDI_00980 1.9e-07 K Transcriptional regulator
KEFIEGDI_00981 1.1e-250 aprX O Belongs to the peptidase S8 family
KEFIEGDI_00982 2e-160 ymaE S Metallo-beta-lactamase superfamily
KEFIEGDI_00983 4.4e-61 ymzB
KEFIEGDI_00984 6.6e-103 pksA K Transcriptional regulator
KEFIEGDI_00985 9.6e-95 ymcC S Membrane
KEFIEGDI_00986 3.3e-69 S Regulatory protein YrvL
KEFIEGDI_00987 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KEFIEGDI_00988 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KEFIEGDI_00989 2.2e-88 cotE S Spore coat protein
KEFIEGDI_00990 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
KEFIEGDI_00991 7.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KEFIEGDI_00992 3e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KEFIEGDI_00993 5.6e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
KEFIEGDI_00994 1.2e-36 spoVS S Stage V sporulation protein S
KEFIEGDI_00995 1.9e-152 ymdB S protein conserved in bacteria
KEFIEGDI_00996 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
KEFIEGDI_00997 1.1e-212 pbpX V Beta-lactamase
KEFIEGDI_00998 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KEFIEGDI_00999 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
KEFIEGDI_01000 1.6e-100 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KEFIEGDI_01001 1.8e-122 ymfM S protein conserved in bacteria
KEFIEGDI_01002 7.9e-143 ymfK S Protein of unknown function (DUF3388)
KEFIEGDI_01003 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
KEFIEGDI_01004 1.1e-127 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
KEFIEGDI_01005 6e-241 ymfH S zinc protease
KEFIEGDI_01006 3e-232 ymfF S Peptidase M16
KEFIEGDI_01007 3.2e-204 ymfD EGP Major facilitator Superfamily
KEFIEGDI_01008 1.4e-133 ymfC K Transcriptional regulator
KEFIEGDI_01009 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KEFIEGDI_01010 4.4e-32 S YlzJ-like protein
KEFIEGDI_01011 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
KEFIEGDI_01012 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KEFIEGDI_01013 5.2e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KEFIEGDI_01014 5e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KEFIEGDI_01015 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KEFIEGDI_01016 2.4e-107 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
KEFIEGDI_01017 2.5e-161 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
KEFIEGDI_01018 2.6e-42 ymxH S YlmC YmxH family
KEFIEGDI_01019 3.7e-232 pepR S Belongs to the peptidase M16 family
KEFIEGDI_01020 3e-181 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
KEFIEGDI_01021 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KEFIEGDI_01022 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KEFIEGDI_01023 6.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KEFIEGDI_01024 1.8e-170 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KEFIEGDI_01025 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KEFIEGDI_01026 3.9e-44 ylxP S protein conserved in bacteria
KEFIEGDI_01027 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KEFIEGDI_01028 3.1e-47 ylxQ J ribosomal protein
KEFIEGDI_01029 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
KEFIEGDI_01030 1.1e-203 nusA K Participates in both transcription termination and antitermination
KEFIEGDI_01031 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
KEFIEGDI_01032 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KEFIEGDI_01033 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KEFIEGDI_01034 7.7e-233 rasP M zinc metalloprotease
KEFIEGDI_01035 1.2e-213 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KEFIEGDI_01036 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
KEFIEGDI_01037 1.1e-144 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KEFIEGDI_01038 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KEFIEGDI_01039 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KEFIEGDI_01040 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KEFIEGDI_01041 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
KEFIEGDI_01042 4.3e-78 ylxL
KEFIEGDI_01043 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KEFIEGDI_01044 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
KEFIEGDI_01045 1.4e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
KEFIEGDI_01046 4.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
KEFIEGDI_01047 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
KEFIEGDI_01048 1.1e-195 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
KEFIEGDI_01049 7e-156 flhG D Belongs to the ParA family
KEFIEGDI_01050 1.2e-200 flhF N Flagellar biosynthesis regulator FlhF
KEFIEGDI_01051 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KEFIEGDI_01052 5.3e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KEFIEGDI_01053 6.2e-132 fliR N Flagellar biosynthetic protein FliR
KEFIEGDI_01054 2.2e-36 fliQ N Role in flagellar biosynthesis
KEFIEGDI_01055 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
KEFIEGDI_01056 6e-96 fliZ N Flagellar biosynthesis protein, FliO
KEFIEGDI_01057 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
KEFIEGDI_01058 2.8e-181 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KEFIEGDI_01059 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KEFIEGDI_01060 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
KEFIEGDI_01061 4.5e-138 flgG N Flagellar basal body rod
KEFIEGDI_01062 2.3e-72 flgD N Flagellar basal body rod modification protein
KEFIEGDI_01063 6.2e-218 fliK N Flagellar hook-length control protein
KEFIEGDI_01064 6.5e-36 ylxF S MgtE intracellular N domain
KEFIEGDI_01065 1.5e-69 fliJ N Flagellar biosynthesis chaperone
KEFIEGDI_01066 3.6e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
KEFIEGDI_01067 1.7e-105 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
KEFIEGDI_01068 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KEFIEGDI_01069 9.1e-255 fliF N The M ring may be actively involved in energy transduction
KEFIEGDI_01070 1.9e-31 fliE N Flagellar hook-basal body
KEFIEGDI_01071 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
KEFIEGDI_01072 3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
KEFIEGDI_01073 2.1e-105 yuaD
KEFIEGDI_01074 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
KEFIEGDI_01075 2.6e-280 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
KEFIEGDI_01076 1.3e-93 yuaC K Belongs to the GbsR family
KEFIEGDI_01077 2.2e-91 yuaB
KEFIEGDI_01078 1.3e-42 L Integrase core domain
KEFIEGDI_01079 2.5e-11 tnpIS3 L Transposase
KEFIEGDI_01080 1.6e-120 ktrA P COG0569 K transport systems, NAD-binding component
KEFIEGDI_01081 9.6e-234 ktrB P Potassium
KEFIEGDI_01082 1e-38 yiaA S yiaA/B two helix domain
KEFIEGDI_01083 5.3e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KEFIEGDI_01084 3.2e-273 yubD P Major Facilitator Superfamily
KEFIEGDI_01085 8.4e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
KEFIEGDI_01087 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KEFIEGDI_01088 1.8e-196 yubA S transporter activity
KEFIEGDI_01089 7.4e-183 ygjR S Oxidoreductase
KEFIEGDI_01090 6.7e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
KEFIEGDI_01091 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
KEFIEGDI_01092 3.7e-271 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
KEFIEGDI_01093 1.7e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
KEFIEGDI_01094 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
KEFIEGDI_01095 3.3e-238 mcpA NT chemotaxis protein
KEFIEGDI_01096 7.4e-291 mcpA NT chemotaxis protein
KEFIEGDI_01097 2.1e-213 mcpA NT chemotaxis protein
KEFIEGDI_01098 6e-224 mcpA NT chemotaxis protein
KEFIEGDI_01099 2.9e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
KEFIEGDI_01100 1e-35
KEFIEGDI_01101 2.1e-72 yugU S Uncharacterised protein family UPF0047
KEFIEGDI_01102 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
KEFIEGDI_01103 4.9e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
KEFIEGDI_01104 9.2e-116 yugP S Zn-dependent protease
KEFIEGDI_01105 3.7e-36
KEFIEGDI_01106 6.6e-51 mstX S Membrane-integrating protein Mistic
KEFIEGDI_01107 3.1e-181 yugO P COG1226 Kef-type K transport systems
KEFIEGDI_01108 2.7e-67 yugN S YugN-like family
KEFIEGDI_01110 1.6e-260 pgi 5.3.1.9 G Belongs to the GPI family
KEFIEGDI_01111 1e-201 yugK C Dehydrogenase
KEFIEGDI_01112 5.4e-17 yugK C Dehydrogenase
KEFIEGDI_01113 1.6e-79 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
KEFIEGDI_01114 1.8e-127 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
KEFIEGDI_01115 1.1e-34 yuzA S Domain of unknown function (DUF378)
KEFIEGDI_01116 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
KEFIEGDI_01117 2.1e-199 yugH 2.6.1.1 E Aminotransferase
KEFIEGDI_01118 1.6e-85 alaR K Transcriptional regulator
KEFIEGDI_01119 4.9e-156 yugF I Hydrolase
KEFIEGDI_01120 1.6e-39 yugE S Domain of unknown function (DUF1871)
KEFIEGDI_01121 6e-224 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KEFIEGDI_01122 4.3e-231 T PhoQ Sensor
KEFIEGDI_01123 2.2e-69 kapB G Kinase associated protein B
KEFIEGDI_01124 1.2e-114 kapD L the KinA pathway to sporulation
KEFIEGDI_01126 4.2e-184 yuxJ EGP Major facilitator Superfamily
KEFIEGDI_01127 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
KEFIEGDI_01128 1.8e-74 yuxK S protein conserved in bacteria
KEFIEGDI_01129 6.3e-78 yufK S Family of unknown function (DUF5366)
KEFIEGDI_01130 1.3e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KEFIEGDI_01131 1.5e-124 dcuR T COG4565 Response regulator of citrate malate metabolism
KEFIEGDI_01132 4.9e-196 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
KEFIEGDI_01133 6e-272 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
KEFIEGDI_01134 4.2e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
KEFIEGDI_01135 5e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
KEFIEGDI_01136 1.3e-233 maeN C COG3493 Na citrate symporter
KEFIEGDI_01137 5e-15
KEFIEGDI_01138 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KEFIEGDI_01139 2.7e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KEFIEGDI_01140 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KEFIEGDI_01141 4.6e-261 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KEFIEGDI_01142 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KEFIEGDI_01143 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KEFIEGDI_01144 2.6e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
KEFIEGDI_01145 6e-64 ydiI Q protein, possibly involved in aromatic compounds catabolism
KEFIEGDI_01146 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KEFIEGDI_01147 0.0 comP 2.7.13.3 T Histidine kinase
KEFIEGDI_01149 3.1e-149 comQ H Polyprenyl synthetase
KEFIEGDI_01151 1.1e-22 yuzC
KEFIEGDI_01152 2e-230 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
KEFIEGDI_01153 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KEFIEGDI_01154 7.3e-103 pncA Q COG1335 Amidases related to nicotinamidase
KEFIEGDI_01155 1.8e-66 yueI S Protein of unknown function (DUF1694)
KEFIEGDI_01156 7.4e-39 yueH S YueH-like protein
KEFIEGDI_01157 2.5e-30 yueG S Spore germination protein gerPA/gerPF
KEFIEGDI_01158 1.2e-189 yueF S transporter activity
KEFIEGDI_01159 5.2e-71 S Protein of unknown function (DUF2283)
KEFIEGDI_01160 2.2e-24 S Protein of unknown function (DUF2642)
KEFIEGDI_01161 1.1e-95 yueE S phosphohydrolase
KEFIEGDI_01162 3.2e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEFIEGDI_01163 6.6e-65 yueC S Family of unknown function (DUF5383)
KEFIEGDI_01164 0.0 esaA S type VII secretion protein EsaA
KEFIEGDI_01165 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KEFIEGDI_01166 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
KEFIEGDI_01167 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
KEFIEGDI_01168 2.8e-45 esxA S Belongs to the WXG100 family
KEFIEGDI_01169 1.2e-227 yukF QT Transcriptional regulator
KEFIEGDI_01170 6.1e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
KEFIEGDI_01171 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
KEFIEGDI_01172 8.5e-36 mbtH S MbtH-like protein
KEFIEGDI_01173 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEFIEGDI_01174 8.4e-176 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
KEFIEGDI_01175 4.5e-311 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
KEFIEGDI_01176 1.6e-224 entC 5.4.4.2 HQ Isochorismate synthase
KEFIEGDI_01177 3.1e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KEFIEGDI_01178 5.6e-166 besA S Putative esterase
KEFIEGDI_01179 4.1e-120 yuiH S Oxidoreductase molybdopterin binding domain
KEFIEGDI_01180 4.4e-93 bioY S Biotin biosynthesis protein
KEFIEGDI_01181 3.9e-211 yuiF S antiporter
KEFIEGDI_01182 1.1e-278 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KEFIEGDI_01183 2e-77 yuiD S protein conserved in bacteria
KEFIEGDI_01184 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
KEFIEGDI_01185 3.7e-108 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
KEFIEGDI_01186 2.7e-73 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KEFIEGDI_01188 4.2e-200 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
KEFIEGDI_01189 2.6e-208 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
KEFIEGDI_01190 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
KEFIEGDI_01191 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
KEFIEGDI_01192 7.5e-53
KEFIEGDI_01193 2.3e-104 ycnK K COG1349 Transcriptional regulators of sugar metabolism
KEFIEGDI_01194 4.3e-305 ycnJ P protein, homolog of Cu resistance protein CopC
KEFIEGDI_01195 3.9e-97 ycnI S protein conserved in bacteria
KEFIEGDI_01196 4.6e-143 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEFIEGDI_01197 6.1e-149 glcU U Glucose uptake
KEFIEGDI_01198 6.4e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KEFIEGDI_01199 4.1e-245 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KEFIEGDI_01200 1.5e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KEFIEGDI_01201 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
KEFIEGDI_01202 1.6e-45 ycnE S Monooxygenase
KEFIEGDI_01203 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
KEFIEGDI_01204 1.2e-152 ycnC K Transcriptional regulator
KEFIEGDI_01205 3.2e-251 ycnB EGP Major facilitator Superfamily
KEFIEGDI_01206 8.8e-165 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
KEFIEGDI_01207 1.1e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
KEFIEGDI_01208 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEFIEGDI_01209 7.7e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEFIEGDI_01210 1.6e-231 lysC 2.7.2.4 E Belongs to the aspartokinase family
KEFIEGDI_01214 3.1e-71 S aspartate phosphatase
KEFIEGDI_01215 1.1e-259 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
KEFIEGDI_01216 2.3e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEFIEGDI_01217 9.6e-203 yclI V ABC transporter (permease) YclI
KEFIEGDI_01218 7.3e-121 yclH P ABC transporter
KEFIEGDI_01219 1.9e-190 gerKB F Spore germination protein
KEFIEGDI_01220 3e-226 gerKC S spore germination
KEFIEGDI_01221 2.5e-276 gerKA EG Spore germination protein
KEFIEGDI_01223 1.8e-296 yclG M Pectate lyase superfamily protein
KEFIEGDI_01224 2.7e-261 dtpT E amino acid peptide transporter
KEFIEGDI_01225 4.5e-97 yclE 3.4.11.5 S Alpha beta hydrolase
KEFIEGDI_01226 5.4e-39 yclE 3.4.11.5 S Alpha beta hydrolase
KEFIEGDI_01227 3.4e-08 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
KEFIEGDI_01228 7.1e-54 bsdA K LysR substrate binding domain
KEFIEGDI_01229 3e-56 bsdA K LysR substrate binding domain
KEFIEGDI_01230 3.2e-139 tcyA ET Belongs to the bacterial solute-binding protein 3 family
KEFIEGDI_01231 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
KEFIEGDI_01232 8.2e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KEFIEGDI_01233 1.7e-114 yczE S membrane
KEFIEGDI_01234 8e-112 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
KEFIEGDI_01235 4.7e-249 ycxD K GntR family transcriptional regulator
KEFIEGDI_01236 2.3e-18 ycxC EG EamA-like transporter family
KEFIEGDI_01237 2.2e-39 ycxC EG EamA-like transporter family
KEFIEGDI_01238 2.5e-66 ycxC EG EamA-like transporter family
KEFIEGDI_01239 2.1e-89 S YcxB-like protein
KEFIEGDI_01240 6.9e-84 EGP Major Facilitator Superfamily
KEFIEGDI_01241 8.7e-87 EGP Major Facilitator Superfamily
KEFIEGDI_01242 1.8e-138 srfAD Q thioesterase
KEFIEGDI_01243 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
KEFIEGDI_01244 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEFIEGDI_01245 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEFIEGDI_01246 1.3e-63 hxlR K transcriptional
KEFIEGDI_01247 4e-105 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
KEFIEGDI_01248 1.9e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
KEFIEGDI_01249 3.8e-182 tlpC 2.7.13.3 NT chemotaxis protein
KEFIEGDI_01250 7.8e-71 nucA M Deoxyribonuclease NucA/NucB
KEFIEGDI_01251 5e-69 nin S Competence protein J (ComJ)
KEFIEGDI_01252 2.6e-293 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KEFIEGDI_01253 2.7e-121 S AAA domain
KEFIEGDI_01254 9.3e-24
KEFIEGDI_01255 3.1e-45 K MarR family
KEFIEGDI_01256 6.6e-51 yckD S Protein of unknown function (DUF2680)
KEFIEGDI_01257 2.3e-35 yckC S membrane
KEFIEGDI_01260 4.9e-130 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
KEFIEGDI_01261 3e-114 yecS P COG0765 ABC-type amino acid transport system, permease component
KEFIEGDI_01262 2.3e-196 yciC S GTPases (G3E family)
KEFIEGDI_01263 1.2e-171 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
KEFIEGDI_01264 3.8e-221 nasA P COG2223 Nitrate nitrite transporter
KEFIEGDI_01265 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
KEFIEGDI_01266 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KEFIEGDI_01267 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KEFIEGDI_01268 1.3e-56 nirD 1.7.1.15 P Nitrite reductase
KEFIEGDI_01269 3.5e-274 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
KEFIEGDI_01270 8.4e-190 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KEFIEGDI_01271 5.3e-104 I alpha/beta hydrolase fold
KEFIEGDI_01272 1e-138 ycgR S permeases
KEFIEGDI_01273 5.7e-147 ycgQ S membrane
KEFIEGDI_01274 1.1e-226 ycgP QT COG2508 Regulator of polyketide synthase expression
KEFIEGDI_01275 9.9e-261 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KEFIEGDI_01276 2.4e-292 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
KEFIEGDI_01277 1.1e-167 ycgM E Proline dehydrogenase
KEFIEGDI_01278 8.3e-145 ycgL S Predicted nucleotidyltransferase
KEFIEGDI_01279 4.7e-182 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
KEFIEGDI_01280 4.3e-175 oxyR3 K LysR substrate binding domain
KEFIEGDI_01281 1.4e-141 yafE Q ubiE/COQ5 methyltransferase family
KEFIEGDI_01282 1e-07 S YpzI-like protein
KEFIEGDI_01283 1.9e-101 yphA
KEFIEGDI_01284 2.1e-160 seaA S YIEGIA protein
KEFIEGDI_01285 4.6e-28 ypzH
KEFIEGDI_01286 1.1e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KEFIEGDI_01287 8.6e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KEFIEGDI_01288 1.6e-18 yphE S Protein of unknown function (DUF2768)
KEFIEGDI_01289 8.7e-136 yphF
KEFIEGDI_01290 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KEFIEGDI_01291 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KEFIEGDI_01292 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
KEFIEGDI_01293 5e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
KEFIEGDI_01294 2.8e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
KEFIEGDI_01295 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KEFIEGDI_01296 2.9e-193 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KEFIEGDI_01297 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KEFIEGDI_01298 4.7e-140 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
KEFIEGDI_01299 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KEFIEGDI_01300 1e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KEFIEGDI_01301 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
KEFIEGDI_01302 1.8e-292 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KEFIEGDI_01303 3.9e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KEFIEGDI_01304 9.5e-114 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
KEFIEGDI_01305 3.9e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
KEFIEGDI_01306 1.4e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KEFIEGDI_01307 7.2e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KEFIEGDI_01308 1.4e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KEFIEGDI_01309 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KEFIEGDI_01310 4.9e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KEFIEGDI_01311 3.8e-232 S COG0457 FOG TPR repeat
KEFIEGDI_01312 2.8e-99 ypiB S Belongs to the UPF0302 family
KEFIEGDI_01313 4.2e-77 ypiF S Protein of unknown function (DUF2487)
KEFIEGDI_01314 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
KEFIEGDI_01315 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
KEFIEGDI_01316 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
KEFIEGDI_01317 1.1e-99 ypjA S membrane
KEFIEGDI_01318 6.1e-143 ypjB S sporulation protein
KEFIEGDI_01319 1.8e-156 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
KEFIEGDI_01320 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
KEFIEGDI_01321 7e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KEFIEGDI_01322 1.6e-70 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
KEFIEGDI_01323 2.9e-128 bshB1 S proteins, LmbE homologs
KEFIEGDI_01324 3.4e-208 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
KEFIEGDI_01325 8.6e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KEFIEGDI_01326 2.5e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KEFIEGDI_01327 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
KEFIEGDI_01328 6.8e-156 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KEFIEGDI_01329 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KEFIEGDI_01330 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KEFIEGDI_01331 6.7e-23 ypmA S Protein of unknown function (DUF4264)
KEFIEGDI_01332 9.9e-80 ypmB S protein conserved in bacteria
KEFIEGDI_01333 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KEFIEGDI_01334 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
KEFIEGDI_01335 5.7e-129 dnaD L DNA replication protein DnaD
KEFIEGDI_01336 8.3e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KEFIEGDI_01337 8e-93 ypoC
KEFIEGDI_01338 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
KEFIEGDI_01339 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KEFIEGDI_01340 1.4e-161 yppC S Protein of unknown function (DUF2515)
KEFIEGDI_01343 7.5e-11 yppE S Bacterial domain of unknown function (DUF1798)
KEFIEGDI_01345 1.7e-47 yppG S YppG-like protein
KEFIEGDI_01346 7.3e-71 hspX O Belongs to the small heat shock protein (HSP20) family
KEFIEGDI_01347 3.3e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
KEFIEGDI_01348 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
KEFIEGDI_01349 4.3e-236 yprB L RNase_H superfamily
KEFIEGDI_01350 5.3e-90 ypsA S Belongs to the UPF0398 family
KEFIEGDI_01351 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KEFIEGDI_01352 4.6e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KEFIEGDI_01354 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
KEFIEGDI_01355 5.7e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEFIEGDI_01356 4.1e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KEFIEGDI_01357 3.3e-186 ptxS K transcriptional
KEFIEGDI_01358 1.1e-186 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
KEFIEGDI_01359 1.3e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
KEFIEGDI_01360 1.9e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
KEFIEGDI_01361 3.3e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KEFIEGDI_01362 1.1e-96 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KEFIEGDI_01363 9.5e-226 pbuX F xanthine
KEFIEGDI_01364 2.1e-205 bcsA Q Naringenin-chalcone synthase
KEFIEGDI_01365 1.5e-86 ypbQ S protein conserved in bacteria
KEFIEGDI_01366 0.0 ypbR S Dynamin family
KEFIEGDI_01367 1e-38 ypbS S Protein of unknown function (DUF2533)
KEFIEGDI_01368 2e-07
KEFIEGDI_01369 4.4e-166 polA 2.7.7.7 L 5'3' exonuclease
KEFIEGDI_01371 2.7e-67 rnhA 3.1.26.4 L Ribonuclease
KEFIEGDI_01372 6.3e-120 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KEFIEGDI_01373 4.4e-126 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
KEFIEGDI_01374 2.6e-27 ypeQ S Zinc-finger
KEFIEGDI_01375 1.8e-30 S Protein of unknown function (DUF2564)
KEFIEGDI_01376 5e-16 degR
KEFIEGDI_01377 7.9e-31 cspD K Cold-shock protein
KEFIEGDI_01378 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
KEFIEGDI_01379 4.7e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KEFIEGDI_01380 2.6e-88 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
KEFIEGDI_01381 1.3e-24 ypgQ S phosphohydrolase
KEFIEGDI_01382 5.2e-66 ypgQ S phosphohydrolase
KEFIEGDI_01383 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
KEFIEGDI_01384 2e-192 yceH P Belongs to the TelA family
KEFIEGDI_01385 0.0 yceG S Putative component of 'biosynthetic module'
KEFIEGDI_01386 1.4e-136 terC P Protein of unknown function (DUF475)
KEFIEGDI_01387 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
KEFIEGDI_01388 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
KEFIEGDI_01389 1.3e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
KEFIEGDI_01390 7.5e-183 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KEFIEGDI_01391 1.1e-134 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KEFIEGDI_01392 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KEFIEGDI_01393 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
KEFIEGDI_01394 2.1e-35 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
KEFIEGDI_01395 3.7e-82 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
KEFIEGDI_01396 1.1e-146 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
KEFIEGDI_01397 1.6e-15 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
KEFIEGDI_01398 5.2e-139 IQ Enoyl-(Acyl carrier protein) reductase
KEFIEGDI_01399 3.6e-173 S response regulator aspartate phosphatase
KEFIEGDI_01400 1.6e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
KEFIEGDI_01401 1.8e-257 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
KEFIEGDI_01402 3.6e-271 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
KEFIEGDI_01403 6.6e-177 ycdA S Domain of unknown function (DUF5105)
KEFIEGDI_01404 4.6e-174 yccK C Aldo keto reductase
KEFIEGDI_01405 4.2e-201 natB CP ABC-2 family transporter protein
KEFIEGDI_01406 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
KEFIEGDI_01407 1.2e-126 lytR_2 T LytTr DNA-binding domain
KEFIEGDI_01408 7.3e-159 2.7.13.3 T GHKL domain
KEFIEGDI_01409 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
KEFIEGDI_01410 4.6e-56 S RDD family
KEFIEGDI_01411 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
KEFIEGDI_01412 4.2e-198 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KEFIEGDI_01413 3.1e-101 yxaF K Transcriptional regulator
KEFIEGDI_01414 1.8e-230 lmrB EGP the major facilitator superfamily
KEFIEGDI_01415 4.7e-202 ycbU E Selenocysteine lyase
KEFIEGDI_01416 1.9e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KEFIEGDI_01417 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KEFIEGDI_01418 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KEFIEGDI_01419 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
KEFIEGDI_01420 3.3e-135 ycbR T vWA found in TerF C terminus
KEFIEGDI_01421 2.2e-75 sleB 3.5.1.28 M Cell wall
KEFIEGDI_01422 2.6e-51 ycbP S Protein of unknown function (DUF2512)
KEFIEGDI_01423 2.6e-36 S ABC-2 family transporter protein
KEFIEGDI_01424 3.4e-169 eamA1 EG spore germination
KEFIEGDI_01425 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
KEFIEGDI_01426 2.1e-117 ycbJ S Macrolide 2'-phosphotransferase
KEFIEGDI_01427 1.1e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
KEFIEGDI_01428 2.1e-123 ycbG K FCD
KEFIEGDI_01429 7.2e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KEFIEGDI_01430 7.7e-255 gudP G COG0477 Permeases of the major facilitator superfamily
KEFIEGDI_01431 1.2e-272 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KEFIEGDI_01432 1.9e-172 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
KEFIEGDI_01433 1e-168 glnL T Regulator
KEFIEGDI_01434 3.9e-81 phoQ 2.7.13.3 T Histidine kinase
KEFIEGDI_01435 2e-18 phoQ 2.7.13.3 T Histidine kinase
KEFIEGDI_01436 3.2e-84 phoQ 2.7.13.3 T Histidine kinase
KEFIEGDI_01437 5.7e-149 glsA 3.5.1.2 E Belongs to the glutaminase family
KEFIEGDI_01438 1.2e-74 agcS E Sodium alanine symporter
KEFIEGDI_01439 7.6e-167 agcS E Sodium alanine symporter
KEFIEGDI_01440 3e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
KEFIEGDI_01441 2.6e-261 mmuP E amino acid
KEFIEGDI_01442 6.1e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KEFIEGDI_01444 4.9e-128 K UTRA
KEFIEGDI_01445 4.4e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KEFIEGDI_01446 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KEFIEGDI_01447 6.4e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KEFIEGDI_01448 4.3e-191 yceA S Belongs to the UPF0176 family
KEFIEGDI_01449 2.6e-247 S Erythromycin esterase
KEFIEGDI_01450 2e-45 ybfN
KEFIEGDI_01451 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
KEFIEGDI_01452 2.7e-85 ybfM S SNARE associated Golgi protein
KEFIEGDI_01453 9.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KEFIEGDI_01454 2.2e-165 S Alpha/beta hydrolase family
KEFIEGDI_01456 2.6e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
KEFIEGDI_01457 2.9e-210 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KEFIEGDI_01458 1.5e-66 M nucleic acid phosphodiester bond hydrolysis
KEFIEGDI_01459 8.7e-73
KEFIEGDI_01460 1.9e-146 draG 3.2.2.24 O ADP-ribosylglycohydrolase
KEFIEGDI_01461 5.9e-228 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
KEFIEGDI_01463 9.3e-223 ybfB G COG0477 Permeases of the major facilitator superfamily
KEFIEGDI_01464 3.8e-80 ybfA 3.4.15.5 K FR47-like protein
KEFIEGDI_01465 1.5e-34 S Protein of unknown function (DUF2651)
KEFIEGDI_01466 2.8e-257 glpT G -transporter
KEFIEGDI_01467 3.2e-161 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KEFIEGDI_01468 1.8e-290 ybeC E amino acid
KEFIEGDI_01469 4.9e-41 ybyB
KEFIEGDI_01470 9.3e-211 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
KEFIEGDI_01471 5.3e-57 ybxI 3.5.2.6 V beta-lactamase
KEFIEGDI_01472 4.9e-66 ybxI 3.5.2.6 V beta-lactamase
KEFIEGDI_01473 4.9e-30 ybxH S Family of unknown function (DUF5370)
KEFIEGDI_01474 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
KEFIEGDI_01475 5.7e-29 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
KEFIEGDI_01476 4.9e-113
KEFIEGDI_01479 7.9e-20
KEFIEGDI_01480 2.7e-51
KEFIEGDI_01481 0.0 L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
KEFIEGDI_01482 8.9e-161 S Domain of unknown function (DUF1998)
KEFIEGDI_01484 2.3e-15 S Tetratricopeptide repeat
KEFIEGDI_01485 1.6e-68 S Tetratricopeptide repeat
KEFIEGDI_01487 1.3e-28 S Colicin immunity protein / pyocin immunity protein
KEFIEGDI_01489 1.6e-82 S Protein of unknown function, DUF600
KEFIEGDI_01490 0.0 L nucleic acid phosphodiester bond hydrolysis
KEFIEGDI_01491 5.5e-173 3.4.24.40 CO amine dehydrogenase activity
KEFIEGDI_01492 1.6e-210 S Tetratricopeptide repeat
KEFIEGDI_01494 2.7e-126 yeeN K transcriptional regulatory protein
KEFIEGDI_01496 6.7e-99 dhaR3 K Transcriptional regulator
KEFIEGDI_01497 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
KEFIEGDI_01498 1.5e-45 cotJB S CotJB protein
KEFIEGDI_01499 5.2e-104 cotJC P Spore Coat
KEFIEGDI_01500 7.4e-100 yesJ K Acetyltransferase (GNAT) family
KEFIEGDI_01502 4.5e-101 yesL S Protein of unknown function, DUF624
KEFIEGDI_01503 0.0 yesM 2.7.13.3 T Histidine kinase
KEFIEGDI_01504 2.6e-200 yesN K helix_turn_helix, arabinose operon control protein
KEFIEGDI_01505 3.6e-246 yesO G Bacterial extracellular solute-binding protein
KEFIEGDI_01506 4.7e-171 yesP G Binding-protein-dependent transport system inner membrane component
KEFIEGDI_01507 9.1e-164 yesQ P Binding-protein-dependent transport system inner membrane component
KEFIEGDI_01508 2.9e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
KEFIEGDI_01509 0.0 yesS K Transcriptional regulator
KEFIEGDI_01510 1.4e-132 E GDSL-like Lipase/Acylhydrolase
KEFIEGDI_01511 3.5e-128 yesU S Domain of unknown function (DUF1961)
KEFIEGDI_01512 5.7e-112 yesV S Protein of unknown function, DUF624
KEFIEGDI_01513 1e-108 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
KEFIEGDI_01514 1.5e-238 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
KEFIEGDI_01515 2e-25 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
KEFIEGDI_01516 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
KEFIEGDI_01517 9.8e-123 yesY E GDSL-like Lipase/Acylhydrolase
KEFIEGDI_01518 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
KEFIEGDI_01519 0.0 yetA
KEFIEGDI_01520 2.4e-289 lplA G Bacterial extracellular solute-binding protein
KEFIEGDI_01521 8.5e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
KEFIEGDI_01522 3.8e-162 lplC G Binding-protein-dependent transport system inner membrane component
KEFIEGDI_01523 4.8e-249 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
KEFIEGDI_01524 2.6e-121 yetF S membrane
KEFIEGDI_01525 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
KEFIEGDI_01526 2.1e-27 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KEFIEGDI_01527 1.7e-14 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KEFIEGDI_01528 8.7e-25
KEFIEGDI_01529 1.3e-143 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KEFIEGDI_01530 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
KEFIEGDI_01531 1.2e-104 yetJ S Belongs to the BI1 family
KEFIEGDI_01532 7.5e-153 yetK EG EamA-like transporter family
KEFIEGDI_01533 9.5e-54 yetL K helix_turn_helix multiple antibiotic resistance protein
KEFIEGDI_01534 3.6e-199 yetN S Protein of unknown function (DUF3900)
KEFIEGDI_01535 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
KEFIEGDI_01536 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KEFIEGDI_01537 1e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
KEFIEGDI_01538 1.9e-172 yfnG 4.2.1.45 M dehydratase
KEFIEGDI_01539 7.1e-180 yfnF M Nucleotide-diphospho-sugar transferase
KEFIEGDI_01540 5.1e-223 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
KEFIEGDI_01541 4.7e-187 yfnD M Nucleotide-diphospho-sugar transferase
KEFIEGDI_01542 1.1e-204 fsr P COG0477 Permeases of the major facilitator superfamily
KEFIEGDI_01543 2.8e-131 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KEFIEGDI_01544 2.4e-240 yfnA E amino acid
KEFIEGDI_01545 4.1e-278 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KEFIEGDI_01546 4.6e-112 yfmS NT chemotaxis protein
KEFIEGDI_01547 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KEFIEGDI_01548 5.7e-74 yfmQ S Uncharacterised protein from bacillus cereus group
KEFIEGDI_01549 1.4e-69 yfmP K transcriptional
KEFIEGDI_01550 5.6e-209 yfmO EGP Major facilitator Superfamily
KEFIEGDI_01551 2e-23
KEFIEGDI_01552 1.6e-07
KEFIEGDI_01556 9.5e-110 S aspartate phosphatase
KEFIEGDI_01557 2.4e-178 A Pre-toxin TG
KEFIEGDI_01558 8.3e-67 S Immunity protein 70
KEFIEGDI_01559 3.8e-108 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
KEFIEGDI_01560 3.8e-18 S Bacteriophage holin family
KEFIEGDI_01562 9e-09
KEFIEGDI_01563 3.1e-86
KEFIEGDI_01564 2.8e-61
KEFIEGDI_01565 1.3e-103 mur1 NU Prophage endopeptidase tail
KEFIEGDI_01566 2.2e-42 S Phage tail protein
KEFIEGDI_01567 4.7e-149 D Phage-related minor tail protein
KEFIEGDI_01569 2.3e-52 S phage major tail protein, phi13 family
KEFIEGDI_01570 1.5e-17
KEFIEGDI_01571 9.5e-15 S Bacteriophage HK97-gp10, putative tail-component
KEFIEGDI_01572 2.1e-07 S head-tail adaptor
KEFIEGDI_01573 2.3e-10 S Phage gp6-like head-tail connector protein
KEFIEGDI_01574 4.8e-89 S Phage capsid family
KEFIEGDI_01575 1.9e-48 S Caudovirus prohead serine protease
KEFIEGDI_01576 2.5e-105 S Phage portal protein
KEFIEGDI_01577 8.5e-150 S Phage Terminase
KEFIEGDI_01578 3.1e-18
KEFIEGDI_01579 5.1e-28 L HNH endonuclease
KEFIEGDI_01581 6.1e-10
KEFIEGDI_01583 7.8e-33 wecC 1.1.1.336 M ArpU family transcriptional regulator
KEFIEGDI_01584 4e-19 S Phage-like element PBSX protein XtrA
KEFIEGDI_01585 3.2e-22
KEFIEGDI_01586 3.3e-170 dnaB 3.6.4.12 L replicative DNA helicase
KEFIEGDI_01587 2.5e-27 S Loader and inhibitor of phage G40P
KEFIEGDI_01588 4.4e-98 L DnaD domain protein
KEFIEGDI_01590 2.6e-11
KEFIEGDI_01591 2.7e-88 S Phage regulatory protein Rha (Phage_pRha)
KEFIEGDI_01592 1.7e-15
KEFIEGDI_01595 1.8e-30
KEFIEGDI_01597 5.6e-32 K Helix-turn-helix XRE-family like proteins
KEFIEGDI_01598 7.6e-45 E Zn peptidase
KEFIEGDI_01599 1.8e-156 L Belongs to the 'phage' integrase family
KEFIEGDI_01601 6.7e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KEFIEGDI_01602 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KEFIEGDI_01603 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
KEFIEGDI_01604 1.3e-116 acuB S Domain in cystathionine beta-synthase and other proteins.
KEFIEGDI_01605 4.7e-224 acuC BQ histone deacetylase
KEFIEGDI_01606 2.3e-120 motS N Flagellar motor protein
KEFIEGDI_01607 2.1e-146 motA N flagellar motor
KEFIEGDI_01608 1.7e-182 ccpA K catabolite control protein A
KEFIEGDI_01609 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
KEFIEGDI_01610 1.1e-53 ytxJ O Protein of unknown function (DUF2847)
KEFIEGDI_01611 6.6e-17 ytxH S COG4980 Gas vesicle protein
KEFIEGDI_01612 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KEFIEGDI_01613 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KEFIEGDI_01614 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
KEFIEGDI_01615 3.1e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KEFIEGDI_01616 9.8e-149 ytpQ S Belongs to the UPF0354 family
KEFIEGDI_01617 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KEFIEGDI_01618 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
KEFIEGDI_01619 4.4e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
KEFIEGDI_01620 2.2e-51 ytzB S small secreted protein
KEFIEGDI_01621 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
KEFIEGDI_01622 2.7e-149 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
KEFIEGDI_01623 4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KEFIEGDI_01624 2e-45 ytzH S YtzH-like protein
KEFIEGDI_01625 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
KEFIEGDI_01626 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
KEFIEGDI_01627 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
KEFIEGDI_01628 4.2e-164 ytlQ
KEFIEGDI_01629 2.9e-99 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KEFIEGDI_01630 5.6e-172 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KEFIEGDI_01631 1.5e-269 pepV 3.5.1.18 E Dipeptidase
KEFIEGDI_01632 1e-224 pbuO S permease
KEFIEGDI_01633 5.8e-203 ythQ U Bacterial ABC transporter protein EcsB
KEFIEGDI_01634 4e-130 ythP V ABC transporter
KEFIEGDI_01635 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
KEFIEGDI_01636 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KEFIEGDI_01637 1.5e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KEFIEGDI_01638 3.4e-230 ytfP S HI0933-like protein
KEFIEGDI_01639 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
KEFIEGDI_01642 8e-140 ycsF S Belongs to the UPF0271 (lamB) family
KEFIEGDI_01643 1.4e-212 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
KEFIEGDI_01644 6.9e-147 ycsI S Belongs to the D-glutamate cyclase family
KEFIEGDI_01645 7.2e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
KEFIEGDI_01646 2e-183 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
KEFIEGDI_01647 1.3e-131 kipR K Transcriptional regulator
KEFIEGDI_01648 3.5e-117 ycsK E anatomical structure formation involved in morphogenesis
KEFIEGDI_01650 1.4e-49 yczJ S biosynthesis
KEFIEGDI_01651 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
KEFIEGDI_01652 8.3e-173 ydhF S Oxidoreductase
KEFIEGDI_01653 0.0 mtlR K transcriptional regulator, MtlR
KEFIEGDI_01654 5.3e-289 ydaB IQ acyl-CoA ligase
KEFIEGDI_01655 7.6e-98 ydaC Q Methyltransferase domain
KEFIEGDI_01656 1e-154 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEFIEGDI_01657 6.6e-95 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
KEFIEGDI_01658 1.2e-102 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KEFIEGDI_01659 2.6e-76 ydaG 1.4.3.5 S general stress protein
KEFIEGDI_01660 3e-137 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
KEFIEGDI_01661 3.6e-45 ydzA EGP Major facilitator Superfamily
KEFIEGDI_01662 2.5e-74 lrpC K Transcriptional regulator
KEFIEGDI_01663 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KEFIEGDI_01664 1.8e-76 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
KEFIEGDI_01665 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KEFIEGDI_01666 3.6e-39
KEFIEGDI_01667 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
KEFIEGDI_01668 1.4e-16 ydaS S Membrane
KEFIEGDI_01669 1.4e-27 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
KEFIEGDI_01670 4.2e-37 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
KEFIEGDI_01671 6.8e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
KEFIEGDI_01673 1.2e-55 ydbB G Cupin domain
KEFIEGDI_01674 2.6e-61 ydbC S Domain of unknown function (DUF4937
KEFIEGDI_01675 3e-153 ydbD P Catalase
KEFIEGDI_01676 5.1e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
KEFIEGDI_01677 4e-295 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KEFIEGDI_01678 3.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
KEFIEGDI_01679 4.1e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KEFIEGDI_01680 1.7e-180 ydbI S AI-2E family transporter
KEFIEGDI_01681 4e-170 ydbJ V ABC transporter, ATP-binding protein
KEFIEGDI_01682 3.6e-124 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KEFIEGDI_01683 2.7e-52 ydbL
KEFIEGDI_01684 1.7e-218 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
KEFIEGDI_01685 1.1e-18 S Fur-regulated basic protein B
KEFIEGDI_01686 2.2e-07 S Fur-regulated basic protein A
KEFIEGDI_01687 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KEFIEGDI_01688 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KEFIEGDI_01689 8.7e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KEFIEGDI_01690 3.7e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KEFIEGDI_01691 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KEFIEGDI_01692 2.1e-82 ydbS S Bacterial PH domain
KEFIEGDI_01693 3.3e-259 ydbT S Membrane
KEFIEGDI_01694 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
KEFIEGDI_01695 1.4e-57 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KEFIEGDI_01696 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
KEFIEGDI_01697 9.6e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KEFIEGDI_01698 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
KEFIEGDI_01699 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
KEFIEGDI_01700 1.3e-143 rsbR T Positive regulator of sigma-B
KEFIEGDI_01701 2.6e-56 rsbS T antagonist
KEFIEGDI_01702 2.9e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
KEFIEGDI_01703 7.1e-189 rsbU 3.1.3.3 KT phosphatase
KEFIEGDI_01704 3e-51 rsbV T Belongs to the anti-sigma-factor antagonist family
KEFIEGDI_01705 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
KEFIEGDI_01706 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KEFIEGDI_01707 1.1e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
KEFIEGDI_01708 0.0 yhgF K COG2183 Transcriptional accessory protein
KEFIEGDI_01719 4.1e-159 KLT Protein kinase domain
KEFIEGDI_01726 2.9e-210 KLT Protein kinase domain
KEFIEGDI_01727 3.1e-208 msbA2 3.6.3.44 V ABC transporter
KEFIEGDI_01728 3.3e-43 S transposition, DNA-mediated
KEFIEGDI_01729 1.3e-116 S HTH-like domain
KEFIEGDI_01730 5e-47 ydeH
KEFIEGDI_01731 3.8e-41 L PhoH-like protein
KEFIEGDI_01732 4.1e-49 yneR S Belongs to the HesB IscA family
KEFIEGDI_01733 6.5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KEFIEGDI_01734 6.6e-69 yccU S CoA-binding protein
KEFIEGDI_01735 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KEFIEGDI_01736 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KEFIEGDI_01737 2.3e-12
KEFIEGDI_01738 5e-57 ynfC
KEFIEGDI_01739 1.2e-250 agcS E Sodium alanine symporter
KEFIEGDI_01740 4.5e-216 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
KEFIEGDI_01741 1.3e-43 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
KEFIEGDI_01743 1.4e-161 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
KEFIEGDI_01744 2.3e-75 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
KEFIEGDI_01745 3.7e-182 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
KEFIEGDI_01746 8.5e-53 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
KEFIEGDI_01747 1.2e-26 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
KEFIEGDI_01748 4.1e-71 yngA S membrane
KEFIEGDI_01749 1.7e-162 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KEFIEGDI_01750 5.5e-104 yngC S membrane-associated protein
KEFIEGDI_01751 4e-231 nrnB S phosphohydrolase (DHH superfamily)
KEFIEGDI_01752 1.5e-286 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KEFIEGDI_01753 4.6e-135 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KEFIEGDI_01754 4.4e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
KEFIEGDI_01755 2.5e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
KEFIEGDI_01756 6.8e-248 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
KEFIEGDI_01757 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KEFIEGDI_01758 1.3e-207 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
KEFIEGDI_01759 1.8e-27 S Family of unknown function (DUF5367)
KEFIEGDI_01760 1.5e-302 yngK T Glycosyl hydrolase-like 10
KEFIEGDI_01761 2.3e-63 yngL S Protein of unknown function (DUF1360)
KEFIEGDI_01762 2.5e-43 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
KEFIEGDI_01763 5.1e-309 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
KEFIEGDI_01764 3.7e-55 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
KEFIEGDI_01765 9.6e-164 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
KEFIEGDI_01766 1.2e-92 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEFIEGDI_01767 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEFIEGDI_01768 1.7e-129 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEFIEGDI_01769 4.2e-111 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEFIEGDI_01770 2.4e-147 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEFIEGDI_01771 1.3e-271 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
KEFIEGDI_01772 8.4e-187 yoxA 5.1.3.3 G Aldose 1-epimerase
KEFIEGDI_01773 8.7e-246 yoeA V MATE efflux family protein
KEFIEGDI_01774 4.1e-98 yoeB S IseA DL-endopeptidase inhibitor
KEFIEGDI_01776 2.2e-96 L Integrase
KEFIEGDI_01777 3e-34 yoeD G Helix-turn-helix domain
KEFIEGDI_01778 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KEFIEGDI_01779 4.5e-152 gltR1 K Transcriptional regulator
KEFIEGDI_01780 2e-180 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KEFIEGDI_01781 1e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
KEFIEGDI_01782 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
KEFIEGDI_01783 7.8e-155 gltC K Transcriptional regulator
KEFIEGDI_01784 3.9e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KEFIEGDI_01785 1.3e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KEFIEGDI_01786 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
KEFIEGDI_01787 8.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KEFIEGDI_01788 5.9e-26 yoxC S Bacterial protein of unknown function (DUF948)
KEFIEGDI_01789 6.8e-41 yoxB
KEFIEGDI_01790 2.9e-96 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KEFIEGDI_01791 3.4e-127 V ABC-2 family transporter protein
KEFIEGDI_01792 9.8e-95 V ABC-2 family transporter protein
KEFIEGDI_01793 7.2e-47 V AAA domain, putative AbiEii toxin, Type IV TA system
KEFIEGDI_01794 7.9e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
KEFIEGDI_01795 3.9e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
KEFIEGDI_01796 1.2e-84 gerD
KEFIEGDI_01797 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KEFIEGDI_01798 2.8e-131 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KEFIEGDI_01799 9.7e-66 ybaK S Protein of unknown function (DUF2521)
KEFIEGDI_01800 4.5e-143 ybaJ Q Methyltransferase domain
KEFIEGDI_01801 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
KEFIEGDI_01802 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KEFIEGDI_01803 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KEFIEGDI_01804 2.6e-117 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KEFIEGDI_01805 3.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KEFIEGDI_01806 1.9e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KEFIEGDI_01807 3.6e-58 rplQ J Ribosomal protein L17
KEFIEGDI_01808 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KEFIEGDI_01809 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KEFIEGDI_01810 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KEFIEGDI_01811 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KEFIEGDI_01812 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KEFIEGDI_01813 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
KEFIEGDI_01814 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KEFIEGDI_01815 2.1e-233 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KEFIEGDI_01816 1.8e-72 rplO J binds to the 23S rRNA
KEFIEGDI_01817 1.9e-23 rpmD J Ribosomal protein L30
KEFIEGDI_01818 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KEFIEGDI_01819 4.4e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KEFIEGDI_01820 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KEFIEGDI_01821 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KEFIEGDI_01822 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KEFIEGDI_01823 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KEFIEGDI_01824 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KEFIEGDI_01825 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KEFIEGDI_01826 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KEFIEGDI_01827 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
KEFIEGDI_01828 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KEFIEGDI_01829 6.8e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KEFIEGDI_01830 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KEFIEGDI_01831 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KEFIEGDI_01832 3.2e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KEFIEGDI_01833 2.6e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KEFIEGDI_01834 3e-105 rplD J Forms part of the polypeptide exit tunnel
KEFIEGDI_01835 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KEFIEGDI_01836 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KEFIEGDI_01837 4.4e-180 ybaC 3.4.11.5 S Alpha/beta hydrolase family
KEFIEGDI_01838 2.6e-222 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KEFIEGDI_01839 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KEFIEGDI_01840 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KEFIEGDI_01841 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KEFIEGDI_01842 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
KEFIEGDI_01843 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KEFIEGDI_01844 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KEFIEGDI_01845 3.5e-106 rsmC 2.1.1.172 J Methyltransferase
KEFIEGDI_01846 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KEFIEGDI_01847 8.7e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KEFIEGDI_01848 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KEFIEGDI_01849 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KEFIEGDI_01850 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
KEFIEGDI_01851 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KEFIEGDI_01852 4.4e-115 sigH K Belongs to the sigma-70 factor family
KEFIEGDI_01853 1.2e-88 yacP S RNA-binding protein containing a PIN domain
KEFIEGDI_01854 2.6e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KEFIEGDI_01855 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KEFIEGDI_01856 2.4e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KEFIEGDI_01857 2.1e-117 cysE 2.3.1.30 E Serine acetyltransferase
KEFIEGDI_01858 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KEFIEGDI_01859 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KEFIEGDI_01860 9.4e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KEFIEGDI_01861 4.5e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
KEFIEGDI_01862 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KEFIEGDI_01863 8.1e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KEFIEGDI_01864 0.0 clpC O Belongs to the ClpA ClpB family
KEFIEGDI_01865 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
KEFIEGDI_01866 3.2e-56 mcsA 2.7.14.1 S protein with conserved CXXC pairs
KEFIEGDI_01867 6.4e-76 ctsR K Belongs to the CtsR family
KEFIEGDI_01868 1.3e-182 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KEFIEGDI_01869 3.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
KEFIEGDI_01870 6.1e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KEFIEGDI_01871 1.8e-23 S Family of unknown function (DUF5359)
KEFIEGDI_01872 1.2e-107 ypfA M Flagellar protein YcgR
KEFIEGDI_01873 4.6e-252 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
KEFIEGDI_01874 7e-151 sleB 3.5.1.28 M Spore cortex-lytic enzyme
KEFIEGDI_01875 1.5e-118 prsW S Involved in the degradation of specific anti-sigma factors
KEFIEGDI_01876 1.1e-175 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
KEFIEGDI_01877 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
KEFIEGDI_01878 9.1e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KEFIEGDI_01879 4e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
KEFIEGDI_01880 2.8e-81 ypbF S Protein of unknown function (DUF2663)
KEFIEGDI_01881 8.2e-78 ypbE M Lysin motif
KEFIEGDI_01882 1.1e-99 ypbD S metal-dependent membrane protease
KEFIEGDI_01883 4.7e-282 recQ 3.6.4.12 L DNA helicase
KEFIEGDI_01884 1.2e-199 ypbB 5.1.3.1 S protein conserved in bacteria
KEFIEGDI_01885 4.7e-41 fer C Ferredoxin
KEFIEGDI_01886 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KEFIEGDI_01887 7.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KEFIEGDI_01888 4.2e-133 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KEFIEGDI_01889 5.5e-187 rsiX
KEFIEGDI_01890 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
KEFIEGDI_01891 0.0 resE 2.7.13.3 T Histidine kinase
KEFIEGDI_01892 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEFIEGDI_01893 4.4e-214 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
KEFIEGDI_01894 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
KEFIEGDI_01895 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
KEFIEGDI_01896 2e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KEFIEGDI_01897 1.9e-87 spmB S Spore maturation protein
KEFIEGDI_01898 5.9e-103 spmA S Spore maturation protein
KEFIEGDI_01899 4e-212 dacB 3.4.16.4 M Belongs to the peptidase S11 family
KEFIEGDI_01900 7.6e-97 ypuI S Protein of unknown function (DUF3907)
KEFIEGDI_01901 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KEFIEGDI_01902 1.2e-127 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KEFIEGDI_01903 1e-90 ypuF S Domain of unknown function (DUF309)
KEFIEGDI_01904 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KEFIEGDI_01905 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KEFIEGDI_01906 2.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KEFIEGDI_01907 9.7e-115 ribE 2.5.1.9 H Riboflavin synthase
KEFIEGDI_01908 8.4e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KEFIEGDI_01909 7.8e-55 ypuD
KEFIEGDI_01910 3.6e-94 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KEFIEGDI_01912 6.6e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
KEFIEGDI_01915 4.7e-09 eaeH M Domain of Unknown Function (DUF1259)
KEFIEGDI_01917 7.1e-12 L COG3666 Transposase and inactivated derivatives
KEFIEGDI_01918 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KEFIEGDI_01919 3.6e-149 ypuA S Secreted protein
KEFIEGDI_01920 1.2e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KEFIEGDI_01921 4.1e-270 spoVAF EG Stage V sporulation protein AF
KEFIEGDI_01922 4e-110 spoVAEA S stage V sporulation protein
KEFIEGDI_01923 2.9e-57 spoVAEB S stage V sporulation protein
KEFIEGDI_01924 2e-191 spoVAD I Stage V sporulation protein AD
KEFIEGDI_01925 4.3e-77 spoVAC S stage V sporulation protein AC
KEFIEGDI_01926 1.3e-67 spoVAB S Stage V sporulation protein AB
KEFIEGDI_01927 9.6e-112 spoVAA S Stage V sporulation protein AA
KEFIEGDI_01928 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KEFIEGDI_01929 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
KEFIEGDI_01930 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
KEFIEGDI_01931 6.3e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
KEFIEGDI_01932 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KEFIEGDI_01933 7.5e-230 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KEFIEGDI_01934 2.4e-164 xerD L recombinase XerD
KEFIEGDI_01935 1.4e-36 S Protein of unknown function (DUF4227)
KEFIEGDI_01936 2.4e-80 fur P Belongs to the Fur family
KEFIEGDI_01937 7.4e-107 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
KEFIEGDI_01938 3.2e-30 yqkK
KEFIEGDI_01939 4.1e-133 mleA 1.1.1.38 C malic enzyme
KEFIEGDI_01940 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KEFIEGDI_01941 9.1e-74 cueR K transcriptional
KEFIEGDI_01942 2e-222 yhdR 2.6.1.1 E Aminotransferase
KEFIEGDI_01943 2.1e-239 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
KEFIEGDI_01944 5.5e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KEFIEGDI_01945 1.1e-63 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KEFIEGDI_01946 1.2e-132 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KEFIEGDI_01948 2.1e-202 yhdY M Mechanosensitive ion channel
KEFIEGDI_01949 3.8e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
KEFIEGDI_01950 2.1e-146 yheN G deacetylase
KEFIEGDI_01951 9e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
KEFIEGDI_01952 5.2e-227 nhaC C Na H antiporter
KEFIEGDI_01953 1.4e-82 nhaX T Belongs to the universal stress protein A family
KEFIEGDI_01954 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
KEFIEGDI_01955 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
KEFIEGDI_01956 1.9e-59 yheG GM NAD(P)H-binding
KEFIEGDI_01957 3e-32 yheG GM NAD(P)H-binding
KEFIEGDI_01958 6.3e-28 sspB S spore protein
KEFIEGDI_01959 1.3e-36 yheE S Family of unknown function (DUF5342)
KEFIEGDI_01960 6.9e-264 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
KEFIEGDI_01961 9e-214 yheC HJ YheC/D like ATP-grasp
KEFIEGDI_01962 5e-199 yheB S Belongs to the UPF0754 family
KEFIEGDI_01963 9.5e-48 yheA S Belongs to the UPF0342 family
KEFIEGDI_01964 2.4e-192 yhaZ L DNA alkylation repair enzyme
KEFIEGDI_01965 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
KEFIEGDI_01966 5.1e-292 hemZ H coproporphyrinogen III oxidase
KEFIEGDI_01967 2e-206 yhaU P COG0475 Kef-type K transport systems, membrane components
KEFIEGDI_01968 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
KEFIEGDI_01970 2.9e-132 yhaR 5.3.3.18 I enoyl-CoA hydratase
KEFIEGDI_01971 1.1e-26 S YhzD-like protein
KEFIEGDI_01972 1.2e-166 yhaQ S ABC transporter, ATP-binding protein
KEFIEGDI_01973 9.4e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
KEFIEGDI_01974 4.2e-220 yhaO L DNA repair exonuclease
KEFIEGDI_01975 0.0 yhaN L AAA domain
KEFIEGDI_01976 2e-177 yhaM L Shows a 3'-5' exoribonuclease activity
KEFIEGDI_01977 1.6e-21 yhaL S Sporulation protein YhaL
KEFIEGDI_01978 2.8e-117 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KEFIEGDI_01979 8.7e-90 yhaK S Putative zincin peptidase
KEFIEGDI_01980 1.3e-54 yhaI S Protein of unknown function (DUF1878)
KEFIEGDI_01981 1e-113 hpr K Negative regulator of protease production and sporulation
KEFIEGDI_01982 1.6e-38 yhaH S YtxH-like protein
KEFIEGDI_01983 2.4e-79 trpP S Tryptophan transporter TrpP
KEFIEGDI_01984 1.1e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KEFIEGDI_01985 1.8e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KEFIEGDI_01986 1.8e-136 ecsA V transporter (ATP-binding protein)
KEFIEGDI_01987 1.6e-214 ecsB U ABC transporter
KEFIEGDI_01988 2e-113 ecsC S EcsC protein family
KEFIEGDI_01989 3.5e-227 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KEFIEGDI_01990 3.9e-238 yhfA C membrane
KEFIEGDI_01991 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
KEFIEGDI_01992 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KEFIEGDI_01993 4.5e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KEFIEGDI_01994 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KEFIEGDI_01995 7.7e-266 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KEFIEGDI_01996 1.7e-61 ytkC S Bacteriophage holin family
KEFIEGDI_01997 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
KEFIEGDI_01998 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KEFIEGDI_01999 1.4e-144 ytlC P ABC transporter
KEFIEGDI_02000 9.5e-189 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KEFIEGDI_02001 1.1e-146 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
KEFIEGDI_02002 1.6e-38 ytmB S Protein of unknown function (DUF2584)
KEFIEGDI_02003 2.2e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KEFIEGDI_02004 1.4e-223 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KEFIEGDI_02005 0.0 asnB 6.3.5.4 E Asparagine synthase
KEFIEGDI_02006 2.1e-250 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
KEFIEGDI_02007 2.7e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KEFIEGDI_02008 9.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
KEFIEGDI_02009 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
KEFIEGDI_02010 2.2e-105 ytqB J Putative rRNA methylase
KEFIEGDI_02011 8.1e-190 yhcC S Fe-S oxidoreductase
KEFIEGDI_02012 6.7e-41 ytzC S Protein of unknown function (DUF2524)
KEFIEGDI_02014 5.1e-66 ytrA K GntR family transcriptional regulator
KEFIEGDI_02015 2.7e-160 ytrB P abc transporter atp-binding protein
KEFIEGDI_02016 2.8e-158 P ABC-2 family transporter protein
KEFIEGDI_02017 1.9e-146
KEFIEGDI_02018 9.1e-127 ytrE V ABC transporter, ATP-binding protein
KEFIEGDI_02019 1.6e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
KEFIEGDI_02020 2.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEFIEGDI_02021 3.4e-183 T PhoQ Sensor
KEFIEGDI_02022 1.1e-138 bceA V ABC transporter, ATP-binding protein
KEFIEGDI_02023 0.0 bceB V ABC transporter (permease)
KEFIEGDI_02024 2e-25 yttA 2.7.13.3 S Pfam Transposase IS66
KEFIEGDI_02025 5.1e-210 yttB EGP Major facilitator Superfamily
KEFIEGDI_02026 4.3e-141 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
KEFIEGDI_02027 7.7e-55 ytvB S Protein of unknown function (DUF4257)
KEFIEGDI_02028 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KEFIEGDI_02029 2.1e-51 ytwF P Sulfurtransferase
KEFIEGDI_02030 7.6e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
KEFIEGDI_02031 1.3e-143 amyC P ABC transporter (permease)
KEFIEGDI_02032 6.2e-168 amyD P ABC transporter
KEFIEGDI_02033 1.5e-244 msmE G Bacterial extracellular solute-binding protein
KEFIEGDI_02034 5.2e-187 msmR K Transcriptional regulator
KEFIEGDI_02035 9.2e-172 ytaP S Acetyl xylan esterase (AXE1)
KEFIEGDI_02036 5.8e-140 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
KEFIEGDI_02037 2.5e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
KEFIEGDI_02038 2.2e-213 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KEFIEGDI_02039 1.3e-120 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KEFIEGDI_02040 1.2e-188 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KEFIEGDI_02041 6.6e-218 bioI 1.14.14.46 C Cytochrome P450
KEFIEGDI_02042 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
KEFIEGDI_02043 1.3e-149 ytcP G COG0395 ABC-type sugar transport system, permease component
KEFIEGDI_02044 4.4e-288 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
KEFIEGDI_02045 0.0 ytdP K Transcriptional regulator
KEFIEGDI_02046 1.7e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
KEFIEGDI_02047 2.8e-218 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
KEFIEGDI_02048 1.1e-71 yteS G transport
KEFIEGDI_02049 7.8e-257 yteT S Oxidoreductase family, C-terminal alpha/beta domain
KEFIEGDI_02050 6.5e-114 yteU S Integral membrane protein
KEFIEGDI_02051 3.1e-26 yteV S Sporulation protein Cse60
KEFIEGDI_02052 1.4e-129 S Aspartate phosphatase response regulator
KEFIEGDI_02054 1.3e-123 yecA E amino acid
KEFIEGDI_02055 1.5e-105 K Transcriptional regulator
KEFIEGDI_02056 1.4e-265 cisA2 L Recombinase
KEFIEGDI_02057 9.9e-94 yqaB E IrrE N-terminal-like domain
KEFIEGDI_02059 9.9e-97 adk 2.7.4.3 F adenylate kinase activity
KEFIEGDI_02061 1.1e-32 K sequence-specific DNA binding
KEFIEGDI_02062 9.1e-18 K Helix-turn-helix XRE-family like proteins
KEFIEGDI_02064 4.4e-103
KEFIEGDI_02068 2e-164 yqaJ L YqaJ-like viral recombinase domain
KEFIEGDI_02069 7.2e-150 recT L RecT family
KEFIEGDI_02070 2.9e-176 xkdC L IstB-like ATP binding protein
KEFIEGDI_02072 3.9e-72 rusA L Endodeoxyribonuclease RusA
KEFIEGDI_02073 3.6e-31 yqaO S Phage-like element PBSX protein XtrA
KEFIEGDI_02074 3.3e-34
KEFIEGDI_02075 2.3e-21
KEFIEGDI_02076 8.2e-76 L Transposase
KEFIEGDI_02079 1.3e-76 yqaS L DNA packaging
KEFIEGDI_02080 3.5e-249 S phage terminase, large subunit
KEFIEGDI_02081 1.7e-282 yqbA S portal protein
KEFIEGDI_02082 4.4e-145 S Phage Mu protein F like protein
KEFIEGDI_02083 5.9e-13
KEFIEGDI_02084 8.8e-120 yqbD 2.1.1.72 L Putative phage serine protease XkdF
KEFIEGDI_02085 2.1e-166 xkdG S Phage capsid family
KEFIEGDI_02086 7.9e-46 S YqbF, hypothetical protein domain
KEFIEGDI_02087 1.7e-66 S Protein of unknown function (DUF3199)
KEFIEGDI_02088 1.1e-62 yqbH S Domain of unknown function (DUF3599)
KEFIEGDI_02089 5.6e-86 S Bacteriophage HK97-gp10, putative tail-component
KEFIEGDI_02090 9.6e-74
KEFIEGDI_02091 2.1e-25
KEFIEGDI_02092 2.5e-253 xkdK S Phage tail sheath C-terminal domain
KEFIEGDI_02093 3.6e-76 xkdM S Phage tail tube protein
KEFIEGDI_02094 2e-66 S Phage XkdN-like tail assembly chaperone protein, TAC
KEFIEGDI_02095 0.0 xkdO L Transglycosylase SLT domain
KEFIEGDI_02096 1.3e-112 xkdP S Lysin motif
KEFIEGDI_02097 2.7e-177 yqbQ 3.2.1.96 G NLP P60 protein
KEFIEGDI_02098 2.7e-31 xkdR S Protein of unknown function (DUF2577)
KEFIEGDI_02099 1.9e-66 xkdS S Protein of unknown function (DUF2634)
KEFIEGDI_02100 7.1e-184 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
KEFIEGDI_02101 1.3e-97 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
KEFIEGDI_02102 2.4e-38
KEFIEGDI_02103 2.8e-215
KEFIEGDI_02104 1.7e-54 xkdW S XkdW protein
KEFIEGDI_02105 1.1e-19
KEFIEGDI_02106 7.2e-161 xepA
KEFIEGDI_02107 5.8e-68 S Bacteriophage holin family
KEFIEGDI_02108 1.2e-122 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
KEFIEGDI_02110 6.1e-274 L nucleic acid phosphodiester bond hydrolysis
KEFIEGDI_02111 1.1e-159 EGP Major Facilitator Superfamily
KEFIEGDI_02112 6.5e-29 Q Pyoverdine/dityrosine biosynthesis protein
KEFIEGDI_02113 1.5e-36 Q Pyoverdine/dityrosine biosynthesis protein
KEFIEGDI_02114 9.2e-74 6.3.2.29, 6.3.2.30, 6.3.2.4 M COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ)
KEFIEGDI_02115 9.2e-76 MA20_32325 3.4.17.11 E Peptidase dimerisation domain
KEFIEGDI_02116 2.9e-10 ppaX 3.1.3.18, 3.6.1.1 S Hydrolase
KEFIEGDI_02117 4.8e-182 bamJ E Aminotransferase class I and II
KEFIEGDI_02118 9.3e-178 L AAA domain
KEFIEGDI_02119 2.1e-155
KEFIEGDI_02121 2.3e-24 S Inner spore coat protein D
KEFIEGDI_02125 4.2e-188
KEFIEGDI_02127 4.7e-128 yoqW S Belongs to the SOS response-associated peptidase family
KEFIEGDI_02128 2.1e-146 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
KEFIEGDI_02129 8.2e-75
KEFIEGDI_02131 3.3e-73
KEFIEGDI_02136 1.2e-94 S Protein of unknown function (DUF1273)
KEFIEGDI_02143 1.8e-64
KEFIEGDI_02147 1.7e-08 S YopX protein
KEFIEGDI_02148 3.7e-36
KEFIEGDI_02152 1.1e-33 K Transcriptional regulator
KEFIEGDI_02153 2.1e-177
KEFIEGDI_02154 2e-258 S DNA-sulfur modification-associated
KEFIEGDI_02155 8.9e-198 L Belongs to the 'phage' integrase family
KEFIEGDI_02160 2.5e-105
KEFIEGDI_02161 1e-16
KEFIEGDI_02169 8.6e-197 3.1.21.3 L Domain of unknown function (DUF4942)
KEFIEGDI_02171 8.9e-157
KEFIEGDI_02174 0.0
KEFIEGDI_02175 6.1e-34 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KEFIEGDI_02177 7.6e-206 S Calcineurin-like phosphoesterase superfamily domain
KEFIEGDI_02180 4.7e-171
KEFIEGDI_02181 0.0 gp17a S Terminase-like family
KEFIEGDI_02182 9.8e-275
KEFIEGDI_02183 3.1e-254
KEFIEGDI_02184 6.6e-93
KEFIEGDI_02185 2.4e-184
KEFIEGDI_02186 3.3e-80
KEFIEGDI_02187 5.1e-66
KEFIEGDI_02189 9.4e-118
KEFIEGDI_02190 3e-79
KEFIEGDI_02191 2.3e-72
KEFIEGDI_02192 3.2e-59
KEFIEGDI_02195 2.9e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KEFIEGDI_02196 7.3e-107 ytaF P Probably functions as a manganese efflux pump
KEFIEGDI_02197 1.2e-154 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KEFIEGDI_02198 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KEFIEGDI_02199 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
KEFIEGDI_02200 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEFIEGDI_02201 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
KEFIEGDI_02202 1.8e-242 icd 1.1.1.42 C isocitrate
KEFIEGDI_02203 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
KEFIEGDI_02204 4.7e-71 yeaL S membrane
KEFIEGDI_02205 3.8e-191 ytvI S sporulation integral membrane protein YtvI
KEFIEGDI_02206 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
KEFIEGDI_02207 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KEFIEGDI_02208 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KEFIEGDI_02209 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KEFIEGDI_02210 2.4e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KEFIEGDI_02211 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
KEFIEGDI_02212 0.0 dnaE 2.7.7.7 L DNA polymerase
KEFIEGDI_02213 3.2e-56 ytrH S Sporulation protein YtrH
KEFIEGDI_02214 8.2e-69 ytrI
KEFIEGDI_02215 9.2e-29
KEFIEGDI_02216 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
KEFIEGDI_02217 2.4e-47 ytpI S YtpI-like protein
KEFIEGDI_02218 8e-241 ytoI K transcriptional regulator containing CBS domains
KEFIEGDI_02219 1.7e-130 ytkL S Belongs to the UPF0173 family
KEFIEGDI_02220 4.2e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEFIEGDI_02222 9.9e-266 argH 4.3.2.1 E argininosuccinate lyase
KEFIEGDI_02223 5.1e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KEFIEGDI_02224 2.2e-85 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
KEFIEGDI_02225 9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KEFIEGDI_02226 9.5e-162 ytxK 2.1.1.72 L DNA methylase
KEFIEGDI_02227 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KEFIEGDI_02228 1.5e-66 ytfJ S Sporulation protein YtfJ
KEFIEGDI_02229 8.1e-107 ytfI S Protein of unknown function (DUF2953)
KEFIEGDI_02230 1.5e-86 yteJ S RDD family
KEFIEGDI_02231 8.7e-179 sppA OU signal peptide peptidase SppA
KEFIEGDI_02232 6.3e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KEFIEGDI_02233 0.0 ytcJ S amidohydrolase
KEFIEGDI_02234 1e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KEFIEGDI_02235 1e-28 sspB S spore protein
KEFIEGDI_02236 1e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KEFIEGDI_02237 3.1e-209 iscS2 2.8.1.7 E Cysteine desulfurase
KEFIEGDI_02238 1.4e-237 brnQ E Component of the transport system for branched-chain amino acids
KEFIEGDI_02239 9.5e-271 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KEFIEGDI_02240 2.9e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
KEFIEGDI_02241 8.5e-108 yttP K Transcriptional regulator
KEFIEGDI_02242 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
KEFIEGDI_02243 7.2e-306 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
KEFIEGDI_02244 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KEFIEGDI_02245 3.1e-235 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KEFIEGDI_02246 5.7e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEFIEGDI_02247 9.7e-250 cssS 2.7.13.3 T PhoQ Sensor
KEFIEGDI_02248 4.3e-158 yuxN K Transcriptional regulator
KEFIEGDI_02249 3.6e-260 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KEFIEGDI_02250 3.9e-24 S Protein of unknown function (DUF3970)
KEFIEGDI_02251 1.4e-241 gerAA EG Spore germination protein
KEFIEGDI_02252 3.6e-194 gerAB E Spore germination protein
KEFIEGDI_02253 3.3e-179 gerAC S Spore germination B3/ GerAC like, C-terminal
KEFIEGDI_02254 8.1e-106 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KEFIEGDI_02255 3.5e-186 vraS 2.7.13.3 T Histidine kinase
KEFIEGDI_02256 9.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
KEFIEGDI_02257 1.3e-125 liaG S Putative adhesin
KEFIEGDI_02258 4.7e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
KEFIEGDI_02259 7.3e-62 liaI S membrane
KEFIEGDI_02260 1.2e-225 yvqJ EGP Major facilitator Superfamily
KEFIEGDI_02261 3.9e-99 yvqK 2.5.1.17 S Adenosyltransferase
KEFIEGDI_02262 1.9e-242 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
KEFIEGDI_02263 8.5e-185 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEFIEGDI_02264 2.6e-169 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
KEFIEGDI_02265 1.5e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KEFIEGDI_02266 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
KEFIEGDI_02267 0.0 T PhoQ Sensor
KEFIEGDI_02268 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEFIEGDI_02269 3.6e-22
KEFIEGDI_02270 2.3e-96 yvrI K RNA polymerase
KEFIEGDI_02271 2.4e-19 S YvrJ protein family
KEFIEGDI_02272 8.9e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
KEFIEGDI_02273 4.6e-62 yvrL S Regulatory protein YrvL
KEFIEGDI_02274 1.5e-209 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
KEFIEGDI_02275 7.9e-123 macB V ABC transporter, ATP-binding protein
KEFIEGDI_02276 2e-174 M Efflux transporter rnd family, mfp subunit
KEFIEGDI_02277 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
KEFIEGDI_02278 4.2e-173 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEFIEGDI_02279 2.5e-181 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEFIEGDI_02280 4.5e-177 fhuD P ABC transporter
KEFIEGDI_02281 4.9e-236 yvsH E Arginine ornithine antiporter
KEFIEGDI_02282 6.5e-16 S Small spore protein J (Spore_SspJ)
KEFIEGDI_02283 8.6e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
KEFIEGDI_02284 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KEFIEGDI_02285 2.4e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
KEFIEGDI_02286 1.4e-136 modA P COG0725 ABC-type molybdate transport system, periplasmic component
KEFIEGDI_02287 4e-119 modB P COG4149 ABC-type molybdate transport system, permease component
KEFIEGDI_02288 7.2e-155 yvgN S reductase
KEFIEGDI_02289 3.3e-58 yvgO
KEFIEGDI_02290 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
KEFIEGDI_02291 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
KEFIEGDI_02292 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KEFIEGDI_02293 0.0 helD 3.6.4.12 L DNA helicase
KEFIEGDI_02294 4.1e-107 yvgT S membrane
KEFIEGDI_02295 5.3e-47 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
KEFIEGDI_02296 5.4e-51 2.7.7.73, 2.7.7.80 H ThiF family
KEFIEGDI_02297 1.6e-45
KEFIEGDI_02298 6.9e-48 S Major Facilitator Superfamily
KEFIEGDI_02299 8.8e-57 1.14.11.27 S JmjC domain, hydroxylase
KEFIEGDI_02300 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEFIEGDI_02301 4e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEFIEGDI_02302 4e-165 feuA P Iron-uptake system-binding protein
KEFIEGDI_02303 8e-304 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
KEFIEGDI_02304 1.1e-236 ybbC 3.2.1.52 S protein conserved in bacteria
KEFIEGDI_02305 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
KEFIEGDI_02306 2.8e-254 yfeW 3.4.16.4 V Belongs to the UPF0214 family
KEFIEGDI_02307 6.4e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KEFIEGDI_02308 1.4e-150 ybbH K transcriptional
KEFIEGDI_02309 2e-161 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KEFIEGDI_02310 7.1e-86 ybbJ J acetyltransferase
KEFIEGDI_02311 7.6e-74 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
KEFIEGDI_02317 9.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
KEFIEGDI_02318 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
KEFIEGDI_02319 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KEFIEGDI_02320 8.3e-223 ybbR S protein conserved in bacteria
KEFIEGDI_02321 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KEFIEGDI_02322 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KEFIEGDI_02323 4.9e-165 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KEFIEGDI_02324 1.9e-118 adaA 3.2.2.21 K Transcriptional regulator
KEFIEGDI_02325 4.3e-100 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KEFIEGDI_02326 1.7e-271 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KEFIEGDI_02327 0.0 ybcC S Belongs to the UPF0753 family
KEFIEGDI_02328 3.2e-92 can 4.2.1.1 P carbonic anhydrase
KEFIEGDI_02330 1.9e-46
KEFIEGDI_02331 1.4e-60 ybcI S Uncharacterized conserved protein (DUF2294)
KEFIEGDI_02332 1.3e-197 ybcL EGP Major facilitator Superfamily
KEFIEGDI_02333 2.6e-07 tnsA L TnsA endonuclease N terminal
KEFIEGDI_02334 6.3e-122 V ABC transporter ATP-binding protein
KEFIEGDI_02335 7.3e-86 S ABC-2 family transporter protein
KEFIEGDI_02336 6.9e-49 L Transposase
KEFIEGDI_02337 1.1e-30 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KEFIEGDI_02338 7.8e-79 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KEFIEGDI_02339 1.3e-122 T Transcriptional regulatory protein, C terminal
KEFIEGDI_02340 2.3e-117 T His Kinase A (phospho-acceptor) domain
KEFIEGDI_02341 1.7e-41 T His Kinase A (phospho-acceptor) domain
KEFIEGDI_02343 3.7e-137 KLT Protein tyrosine kinase
KEFIEGDI_02344 1e-148 ybdN
KEFIEGDI_02345 4.1e-212 ybdO S Domain of unknown function (DUF4885)
KEFIEGDI_02346 4.4e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
KEFIEGDI_02347 1e-255 lytH 3.5.1.28 M COG3103 SH3 domain protein
KEFIEGDI_02349 3.1e-242 hisS 6.1.1.21 J histidyl-tRNA synthetase
KEFIEGDI_02350 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KEFIEGDI_02351 8.4e-134 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
KEFIEGDI_02352 6.3e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
KEFIEGDI_02353 6.8e-69 cymR K Transcriptional regulator
KEFIEGDI_02354 2.6e-211 iscS 2.8.1.7 E Cysteine desulfurase
KEFIEGDI_02355 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KEFIEGDI_02356 1.4e-15 S COG0457 FOG TPR repeat
KEFIEGDI_02357 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KEFIEGDI_02358 6.6e-81 yrrD S protein conserved in bacteria
KEFIEGDI_02359 9.8e-31 yrzR
KEFIEGDI_02360 8e-08 S Protein of unknown function (DUF3918)
KEFIEGDI_02361 7.6e-107 glnP P ABC transporter
KEFIEGDI_02362 8e-109 gluC P ABC transporter
KEFIEGDI_02363 1.5e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
KEFIEGDI_02364 1.4e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KEFIEGDI_02365 5.9e-170 yrrI S AI-2E family transporter
KEFIEGDI_02366 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KEFIEGDI_02367 1.7e-41 yrzL S Belongs to the UPF0297 family
KEFIEGDI_02368 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KEFIEGDI_02369 1.2e-45 yrzB S Belongs to the UPF0473 family
KEFIEGDI_02370 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KEFIEGDI_02371 1.7e-119 yrrM 2.1.1.104 S O-methyltransferase
KEFIEGDI_02372 3.9e-173 yegQ O Peptidase U32
KEFIEGDI_02373 1.8e-245 yegQ O COG0826 Collagenase and related proteases
KEFIEGDI_02374 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
KEFIEGDI_02375 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KEFIEGDI_02376 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
KEFIEGDI_02377 2.5e-60 yrrS S Protein of unknown function (DUF1510)
KEFIEGDI_02378 1e-25 yrzA S Protein of unknown function (DUF2536)
KEFIEGDI_02379 1.2e-117 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
KEFIEGDI_02380 1.6e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KEFIEGDI_02381 2e-169 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
KEFIEGDI_02382 7.5e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KEFIEGDI_02383 1.8e-34 yrhC S YrhC-like protein
KEFIEGDI_02384 2.4e-78 yrhD S Protein of unknown function (DUF1641)
KEFIEGDI_02385 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
KEFIEGDI_02386 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
KEFIEGDI_02388 5.7e-141 focA P Formate nitrite
KEFIEGDI_02390 2.1e-94 yrhH Q methyltransferase
KEFIEGDI_02391 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
KEFIEGDI_02392 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
KEFIEGDI_02393 1.5e-309 yrhL I Acyltransferase family
KEFIEGDI_02394 1.3e-126 rsiV S Protein of unknown function (DUF3298)
KEFIEGDI_02395 2.7e-140 ydbD P Catalase
KEFIEGDI_02396 3e-110 xkdA E IrrE N-terminal-like domain
KEFIEGDI_02397 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
KEFIEGDI_02399 3.9e-156 xkdB K sequence-specific DNA binding
KEFIEGDI_02400 9.2e-118 xkdC L Bacterial dnaA protein
KEFIEGDI_02403 2.3e-09 yqaO S Phage-like element PBSX protein XtrA
KEFIEGDI_02404 3.8e-82 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
KEFIEGDI_02405 2.9e-82 xtmA L phage terminase small subunit
KEFIEGDI_02406 3.3e-189 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
KEFIEGDI_02407 4.2e-101 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
KEFIEGDI_02408 6.7e-41
KEFIEGDI_02409 6.4e-120
KEFIEGDI_02410 1e-190
KEFIEGDI_02411 2.2e-43 xkdW S XkdW protein
KEFIEGDI_02412 4.6e-21 xkdX
KEFIEGDI_02413 3.7e-151 xepA
KEFIEGDI_02414 6.2e-39 xhlA S Haemolysin XhlA
KEFIEGDI_02415 9.3e-40 xhlB S SPP1 phage holin
KEFIEGDI_02416 1.3e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KEFIEGDI_02417 6.7e-23 spoIISB S Stage II sporulation protein SB
KEFIEGDI_02418 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
KEFIEGDI_02419 7.6e-175 pit P phosphate transporter
KEFIEGDI_02420 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
KEFIEGDI_02421 2.3e-240 steT E amino acid
KEFIEGDI_02422 3e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
KEFIEGDI_02423 6e-310 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KEFIEGDI_02424 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KEFIEGDI_02426 7.9e-212 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KEFIEGDI_02427 3.2e-131 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
KEFIEGDI_02428 5.1e-153 dppA E D-aminopeptidase
KEFIEGDI_02429 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KEFIEGDI_02430 9.6e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KEFIEGDI_02431 1.3e-185 dppD P Belongs to the ABC transporter superfamily
KEFIEGDI_02432 0.0 dppE E ABC transporter substrate-binding protein
KEFIEGDI_02434 1.4e-175 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
KEFIEGDI_02435 1.2e-194 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KEFIEGDI_02436 1.7e-162 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KEFIEGDI_02437 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
KEFIEGDI_02438 3.6e-204 pgl 3.1.1.31 G 6-phosphogluconolactonase
KEFIEGDI_02439 7.2e-158 ykgA E Amidinotransferase
KEFIEGDI_02440 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
KEFIEGDI_02441 4e-223 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KEFIEGDI_02442 1.9e-09
KEFIEGDI_02443 7.8e-129 ykjA S Protein of unknown function (DUF421)
KEFIEGDI_02444 2.4e-95 ykkA S Protein of unknown function (DUF664)
KEFIEGDI_02445 1.1e-95 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KEFIEGDI_02446 1.3e-54 ykkC P Multidrug resistance protein
KEFIEGDI_02447 9.1e-50 ykkD P Multidrug resistance protein
KEFIEGDI_02448 6.6e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
KEFIEGDI_02449 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KEFIEGDI_02450 6.9e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KEFIEGDI_02451 1.3e-70 ohrA O Organic hydroperoxide resistance protein
KEFIEGDI_02452 5.7e-74 ohrR K COG1846 Transcriptional regulators
KEFIEGDI_02453 2.4e-71 ohrB O Organic hydroperoxide resistance protein
KEFIEGDI_02454 6.2e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
KEFIEGDI_02456 9.3e-74 azlC E AzlC protein
KEFIEGDI_02457 1e-24 S branched-chain amino acid
KEFIEGDI_02458 7.3e-166 bsn L Ribonuclease
KEFIEGDI_02459 4.9e-232 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
KEFIEGDI_02460 3.3e-236 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
KEFIEGDI_02461 1.6e-185 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KEFIEGDI_02462 9e-110 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
KEFIEGDI_02463 1.5e-147 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
KEFIEGDI_02464 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
KEFIEGDI_02465 4e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
KEFIEGDI_02467 9.3e-56 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
KEFIEGDI_02468 2.1e-277 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
KEFIEGDI_02469 6.5e-219 pbuX F xanthine
KEFIEGDI_02470 2.2e-233 pbuX F Permease family
KEFIEGDI_02471 1.9e-300 pucR QT COG2508 Regulator of polyketide synthase expression
KEFIEGDI_02472 6.2e-257 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
KEFIEGDI_02473 3e-62 yunG
KEFIEGDI_02474 1.3e-170 yunF S Protein of unknown function DUF72
KEFIEGDI_02475 2.2e-140 yunE S membrane transporter protein
KEFIEGDI_02476 4.1e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KEFIEGDI_02477 9.1e-47 yunC S Domain of unknown function (DUF1805)
KEFIEGDI_02478 2.7e-132 yunB S Sporulation protein YunB (Spo_YunB)
KEFIEGDI_02479 1.3e-195 lytH M Peptidase, M23
KEFIEGDI_02480 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KEFIEGDI_02481 2.4e-110 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KEFIEGDI_02482 9.7e-48 yutD S protein conserved in bacteria
KEFIEGDI_02483 8.6e-75 yutE S Protein of unknown function DUF86
KEFIEGDI_02484 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KEFIEGDI_02485 5.6e-86 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
KEFIEGDI_02486 5e-198 yutH S Spore coat protein
KEFIEGDI_02487 4.6e-241 hom 1.1.1.3 E homoserine dehydrogenase
KEFIEGDI_02488 6.8e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KEFIEGDI_02489 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KEFIEGDI_02490 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
KEFIEGDI_02491 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
KEFIEGDI_02492 1.1e-55 yuzD S protein conserved in bacteria
KEFIEGDI_02493 7.7e-199 yutJ 1.6.99.3 C NADH dehydrogenase
KEFIEGDI_02494 3.2e-39 yuzB S Belongs to the UPF0349 family
KEFIEGDI_02495 5.9e-198 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KEFIEGDI_02496 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KEFIEGDI_02497 3.7e-63 erpA S Belongs to the HesB IscA family
KEFIEGDI_02498 5.2e-71 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KEFIEGDI_02499 4.6e-114 paiB K Putative FMN-binding domain
KEFIEGDI_02500 4e-173 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KEFIEGDI_02502 1.7e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
KEFIEGDI_02503 4.2e-236 yumB 1.6.99.3 C NADH dehydrogenase
KEFIEGDI_02504 1.9e-26 yuiB S Putative membrane protein
KEFIEGDI_02505 4e-116 yuiC S protein conserved in bacteria
KEFIEGDI_02506 1.4e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
KEFIEGDI_02507 2.2e-309 oppA E ABC transporter substrate-binding protein
KEFIEGDI_02508 2.3e-165 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KEFIEGDI_02509 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KEFIEGDI_02510 6.8e-198 oppD P Belongs to the ABC transporter superfamily
KEFIEGDI_02511 5.5e-172 oppF E Belongs to the ABC transporter superfamily
KEFIEGDI_02512 2.7e-209 yjbB EGP Major Facilitator Superfamily
KEFIEGDI_02513 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KEFIEGDI_02514 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KEFIEGDI_02515 1.5e-110 yjbE P Integral membrane protein TerC family
KEFIEGDI_02516 1.2e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KEFIEGDI_02517 1.6e-221 yjbF S Competence protein
KEFIEGDI_02518 0.0 pepF E oligoendopeptidase F
KEFIEGDI_02519 1.8e-20
KEFIEGDI_02521 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KEFIEGDI_02522 3.7e-72 yjbI S Bacterial-like globin
KEFIEGDI_02523 4.1e-85 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KEFIEGDI_02524 4.1e-101 yjbK S protein conserved in bacteria
KEFIEGDI_02525 2.7e-61 yjbL S Belongs to the UPF0738 family
KEFIEGDI_02526 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
KEFIEGDI_02527 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KEFIEGDI_02528 5.4e-156 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KEFIEGDI_02529 1.5e-127 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
KEFIEGDI_02530 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KEFIEGDI_02531 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KEFIEGDI_02532 1.3e-105 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
KEFIEGDI_02533 7.5e-216 thiO 1.4.3.19 E Glycine oxidase
KEFIEGDI_02534 2.2e-28 thiS H thiamine diphosphate biosynthetic process
KEFIEGDI_02535 1.4e-133 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
KEFIEGDI_02536 1.4e-184 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KEFIEGDI_02537 2e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KEFIEGDI_02538 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KEFIEGDI_02539 5.5e-52 yjbX S Spore coat protein
KEFIEGDI_02540 8.9e-83 cotZ S Spore coat protein
KEFIEGDI_02541 3.4e-96 cotY S Spore coat protein Z
KEFIEGDI_02542 4e-71 cotX S Spore Coat Protein X and V domain
KEFIEGDI_02543 6.4e-22 cotW
KEFIEGDI_02544 2.3e-55 cotV S Spore Coat Protein X and V domain
KEFIEGDI_02545 4.3e-56 yjcA S Protein of unknown function (DUF1360)
KEFIEGDI_02548 2.9e-38 spoVIF S Stage VI sporulation protein F
KEFIEGDI_02549 0.0 yjcD 3.6.4.12 L DNA helicase
KEFIEGDI_02550 1.4e-37
KEFIEGDI_02551 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KEFIEGDI_02552 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
KEFIEGDI_02553 3.8e-136 yjcH P COG2382 Enterochelin esterase and related enzymes
KEFIEGDI_02554 1.6e-213 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KEFIEGDI_02555 5.5e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KEFIEGDI_02556 4.3e-21 rimJ 2.3.1.128 J Alanine acetyltransferase
KEFIEGDI_02557 6.2e-208 yjcL S Protein of unknown function (DUF819)
KEFIEGDI_02559 5.2e-18
KEFIEGDI_02560 1.5e-149 yidA S hydrolases of the HAD superfamily
KEFIEGDI_02563 1.3e-20 yxeE
KEFIEGDI_02564 5.6e-16 yxeD
KEFIEGDI_02565 1.4e-68
KEFIEGDI_02566 1.6e-174 fhuD P ABC transporter
KEFIEGDI_02567 1.2e-29 yxeA S Protein of unknown function (DUF1093)
KEFIEGDI_02568 2.4e-54 yxdM V ABC transporter (permease)
KEFIEGDI_02569 4.7e-269 yxdM V ABC transporter (permease)
KEFIEGDI_02570 4e-69 yxdL V ABC transporter, ATP-binding protein
KEFIEGDI_02571 1.3e-51 yxdL V ABC transporter, ATP-binding protein
KEFIEGDI_02572 2.6e-64 T PhoQ Sensor
KEFIEGDI_02573 4e-69 T PhoQ Sensor
KEFIEGDI_02574 2.2e-45 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEFIEGDI_02575 5.1e-159 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
KEFIEGDI_02576 3.1e-137 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
KEFIEGDI_02577 3.3e-166 iolH G Xylose isomerase-like TIM barrel
KEFIEGDI_02578 6.1e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
KEFIEGDI_02579 4.3e-234 iolF EGP Major facilitator Superfamily
KEFIEGDI_02580 1e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
KEFIEGDI_02581 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
KEFIEGDI_02582 2.5e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
KEFIEGDI_02583 2.3e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
KEFIEGDI_02584 9.7e-280 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KEFIEGDI_02585 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
KEFIEGDI_02586 9.2e-175 iolS C Aldo keto reductase
KEFIEGDI_02587 1.7e-48 yxcD S Protein of unknown function (DUF2653)
KEFIEGDI_02588 5.6e-245 csbC EGP Major facilitator Superfamily
KEFIEGDI_02589 0.0 htpG O Molecular chaperone. Has ATPase activity
KEFIEGDI_02590 2.6e-149 IQ Enoyl-(Acyl carrier protein) reductase
KEFIEGDI_02594 8.3e-18 ygzD K Transcriptional
KEFIEGDI_02596 1.4e-234 V Peptidase C39 family
KEFIEGDI_02597 1.4e-46 M HlyD family secretion protein
KEFIEGDI_02598 4.5e-76 M HlyD family secretion protein
KEFIEGDI_02600 6.2e-124 yxbF K Bacterial regulatory proteins, tetR family
KEFIEGDI_02601 1.6e-39 yxbF K Bacterial regulatory proteins, tetR family
KEFIEGDI_02602 8.4e-235 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
KEFIEGDI_02603 5.7e-32 yxaI S membrane protein domain
KEFIEGDI_02604 1.6e-78 S PQQ-like domain
KEFIEGDI_02605 1.4e-75 yxaI S membrane protein domain
KEFIEGDI_02606 1.4e-223 P Protein of unknown function (DUF418)
KEFIEGDI_02607 5.4e-197 yxaG 1.13.11.24 S AraC-like ligand binding domain
KEFIEGDI_02608 3.5e-100 yxaF K Transcriptional regulator
KEFIEGDI_02609 1.4e-198 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KEFIEGDI_02610 2.7e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
KEFIEGDI_02611 5e-184 corA P Mediates influx of magnesium ions
KEFIEGDI_02612 6.5e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KEFIEGDI_02613 4.9e-265 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KEFIEGDI_02614 1.1e-43 S YfzA-like protein
KEFIEGDI_02615 5.5e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KEFIEGDI_02616 4.7e-84 yfjM S Psort location Cytoplasmic, score
KEFIEGDI_02617 1.9e-28 yfjL
KEFIEGDI_02618 2.2e-190 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KEFIEGDI_02619 8.5e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KEFIEGDI_02620 2.5e-193 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KEFIEGDI_02621 2.5e-253 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KEFIEGDI_02622 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
KEFIEGDI_02623 1.2e-25 sspH S Belongs to the SspH family
KEFIEGDI_02624 4e-56 yfjF S UPF0060 membrane protein
KEFIEGDI_02625 2.4e-98 yfjD S Family of unknown function (DUF5381)
KEFIEGDI_02626 4.1e-144 yfjC
KEFIEGDI_02627 7.8e-190 yfjB
KEFIEGDI_02628 3.3e-44 yfjA S Belongs to the WXG100 family
KEFIEGDI_02631 1.3e-17 S Protein conserved in bacteria
KEFIEGDI_02633 2.1e-67 S LXG domain of WXG superfamily
KEFIEGDI_02634 8.7e-12 yxiC S Family of unknown function (DUF5344)
KEFIEGDI_02635 1.9e-14 S Domain of unknown function (DUF5082)
KEFIEGDI_02636 1.4e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KEFIEGDI_02637 7.9e-140 glvR K Helix-turn-helix domain, rpiR family
KEFIEGDI_02638 1.2e-294 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KEFIEGDI_02639 5.4e-306 yfiB3 V ABC transporter
KEFIEGDI_02640 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
KEFIEGDI_02641 6.4e-64 mhqP S DoxX
KEFIEGDI_02642 4.5e-160 yfiE 1.13.11.2 S glyoxalase
KEFIEGDI_02643 2.5e-175 K AraC-like ligand binding domain
KEFIEGDI_02644 1.9e-259 iolT EGP Major facilitator Superfamily
KEFIEGDI_02645 2.1e-182 G Xylose isomerase
KEFIEGDI_02646 3.6e-232 S Oxidoreductase
KEFIEGDI_02647 1.2e-216 yxjM T Histidine kinase
KEFIEGDI_02648 1e-111 KT LuxR family transcriptional regulator
KEFIEGDI_02649 5.4e-167 V ABC transporter, ATP-binding protein
KEFIEGDI_02650 3e-140 V ABC-2 family transporter protein
KEFIEGDI_02651 9.6e-50 V ABC-2 family transporter protein
KEFIEGDI_02652 2.3e-199 V COG0842 ABC-type multidrug transport system, permease component
KEFIEGDI_02653 2.2e-68 J Acetyltransferase (GNAT) domain
KEFIEGDI_02654 3.1e-98 padR K transcriptional
KEFIEGDI_02655 4.9e-79 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
KEFIEGDI_02656 1.3e-129 MA20_18170 S membrane transporter protein
KEFIEGDI_02657 3.3e-283 uxaA 4.2.1.7, 4.4.1.24 G Altronate
KEFIEGDI_02658 2.1e-279 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
KEFIEGDI_02659 6.4e-182 exuR K transcriptional
KEFIEGDI_02660 4.1e-226 exuT G Sugar (and other) transporter
KEFIEGDI_02661 8.9e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KEFIEGDI_02662 8.9e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
KEFIEGDI_02663 3.4e-191 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
KEFIEGDI_02664 6e-188 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
KEFIEGDI_02665 2.1e-247 yjmB G symporter YjmB
KEFIEGDI_02666 3.9e-278 uxaC 5.3.1.12 G glucuronate isomerase
KEFIEGDI_02667 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
KEFIEGDI_02668 7.1e-66 yjlC S Protein of unknown function (DUF1641)
KEFIEGDI_02669 2.6e-91 yjlB S Cupin domain
KEFIEGDI_02670 1.9e-175 yjlA EG Putative multidrug resistance efflux transporter
KEFIEGDI_02671 2.2e-134 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
KEFIEGDI_02672 7.5e-119 ybbM S transport system, permease component
KEFIEGDI_02673 1.9e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KEFIEGDI_02674 8.2e-30
KEFIEGDI_02675 8.5e-218 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KEFIEGDI_02676 1.8e-220 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
KEFIEGDI_02678 1.1e-110 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
KEFIEGDI_02680 4.8e-94 yjgD S Protein of unknown function (DUF1641)
KEFIEGDI_02681 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
KEFIEGDI_02682 1.8e-234 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
KEFIEGDI_02683 3.8e-102 yjgB S Domain of unknown function (DUF4309)
KEFIEGDI_02684 4.9e-34 T PhoQ Sensor
KEFIEGDI_02685 4.1e-164 yjfC O Predicted Zn-dependent protease (DUF2268)
KEFIEGDI_02686 1.5e-19 yjfB S Putative motility protein
KEFIEGDI_02687 1.8e-81 S Protein of unknown function (DUF2690)
KEFIEGDI_02688 1.6e-263 xynD 3.5.1.104 G Polysaccharide deacetylase
KEFIEGDI_02690 1.2e-172 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KEFIEGDI_02691 4.2e-29 S Domain of unknown function (DUF4177)
KEFIEGDI_02692 6.8e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KEFIEGDI_02694 4.5e-91 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
KEFIEGDI_02695 1.1e-30 yjdF S Protein of unknown function (DUF2992)
KEFIEGDI_02696 5.5e-183 manA 5.3.1.8 G mannose-6-phosphate isomerase
KEFIEGDI_02697 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
KEFIEGDI_02698 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
KEFIEGDI_02699 4.7e-38 yjcN
KEFIEGDI_02700 4.9e-153 pdaA G deacetylase
KEFIEGDI_02701 1.1e-26 yfjT
KEFIEGDI_02702 5.4e-222 yfkA S YfkB-like domain
KEFIEGDI_02703 3e-148 yfkC M Mechanosensitive ion channel
KEFIEGDI_02704 2e-146 yfkD S YfkD-like protein
KEFIEGDI_02705 6.1e-183 cax P COG0387 Ca2 H antiporter
KEFIEGDI_02706 7.7e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
KEFIEGDI_02707 5e-08
KEFIEGDI_02708 4.8e-143 yihY S Belongs to the UPF0761 family
KEFIEGDI_02709 2.4e-50 yfkI S gas vesicle protein
KEFIEGDI_02710 2e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KEFIEGDI_02711 1.3e-28 yfkK S Belongs to the UPF0435 family
KEFIEGDI_02712 4.4e-206 ydiM EGP Major facilitator Superfamily
KEFIEGDI_02713 1.4e-87 yfkM 1.11.1.6, 3.5.1.124 S protease
KEFIEGDI_02714 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KEFIEGDI_02715 1.1e-124 yfkO C nitroreductase
KEFIEGDI_02716 6.7e-133 treR K transcriptional
KEFIEGDI_02717 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KEFIEGDI_02718 3.2e-256 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KEFIEGDI_02719 3e-84 yfkR S spore germination
KEFIEGDI_02721 4.7e-180 E Spore germination protein
KEFIEGDI_02722 2.2e-252 agcS_1 E Sodium alanine symporter
KEFIEGDI_02723 6e-67 yhdN S Domain of unknown function (DUF1992)
KEFIEGDI_02724 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KEFIEGDI_02725 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
KEFIEGDI_02726 2.1e-137 map 3.4.11.18 E Methionine aminopeptidase
KEFIEGDI_02727 5.3e-50 yflH S Protein of unknown function (DUF3243)
KEFIEGDI_02728 4.1e-19 yflI
KEFIEGDI_02729 8.9e-18 yflJ S Protein of unknown function (DUF2639)
KEFIEGDI_02730 1.4e-121 yflK S protein conserved in bacteria
KEFIEGDI_02731 1.9e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KEFIEGDI_02732 8.1e-215 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KEFIEGDI_02733 1.3e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
KEFIEGDI_02734 3.2e-226 citM C Citrate transporter
KEFIEGDI_02735 1.4e-178 yflP S Tripartite tricarboxylate transporter family receptor
KEFIEGDI_02736 1.9e-116 citT T response regulator
KEFIEGDI_02737 4.1e-287 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KEFIEGDI_02738 5.5e-235 yflS P Sodium:sulfate symporter transmembrane region
KEFIEGDI_02739 7.2e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
KEFIEGDI_02740 2.2e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
KEFIEGDI_02741 2.3e-295 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KEFIEGDI_02742 2e-160 cvfB S protein conserved in bacteria
KEFIEGDI_02743 3.3e-54 yajQ S Belongs to the UPF0234 family
KEFIEGDI_02744 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
KEFIEGDI_02745 4.6e-71 yjcF S Acetyltransferase (GNAT) domain
KEFIEGDI_02746 8.8e-75 yitH K Acetyltransferase (GNAT) domain
KEFIEGDI_02747 1.9e-152 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KEFIEGDI_02748 3.4e-35 mcbG S Pentapeptide repeats (9 copies)
KEFIEGDI_02749 1.5e-197 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KEFIEGDI_02750 1.5e-69 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KEFIEGDI_02751 1.2e-106 argO S Lysine exporter protein LysE YggA
KEFIEGDI_02752 1.2e-24 yisT S DinB family
KEFIEGDI_02753 1.8e-53 yisT S DinB family
KEFIEGDI_02754 4.8e-193 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
KEFIEGDI_02755 7.1e-181 purR K helix_turn _helix lactose operon repressor
KEFIEGDI_02756 1.6e-160 yisR K Transcriptional regulator
KEFIEGDI_02757 5.2e-243 yisQ V Mate efflux family protein
KEFIEGDI_02758 1.5e-117 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
KEFIEGDI_02759 0.0 asnO 6.3.5.4 E Asparagine synthase
KEFIEGDI_02760 1.3e-102 yisN S Protein of unknown function (DUF2777)
KEFIEGDI_02761 0.0 wprA O Belongs to the peptidase S8 family
KEFIEGDI_02762 5.1e-57 yisL S UPF0344 protein
KEFIEGDI_02763 2.1e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
KEFIEGDI_02764 8.5e-173 cotH M Spore Coat
KEFIEGDI_02765 1.5e-22 yisI S Spo0E like sporulation regulatory protein
KEFIEGDI_02766 5.4e-33 gerPA S Spore germination protein
KEFIEGDI_02767 4e-34 gerPB S cell differentiation
KEFIEGDI_02768 5.3e-54 gerPC S Spore germination protein
KEFIEGDI_02769 1.1e-23 gerPD S Spore germination protein
KEFIEGDI_02770 1.2e-62 gerPE S Spore germination protein GerPE
KEFIEGDI_02771 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
KEFIEGDI_02772 2.5e-49 yisB V COG1403 Restriction endonuclease
KEFIEGDI_02773 0.0 sbcC L COG0419 ATPase involved in DNA repair
KEFIEGDI_02774 5.3e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KEFIEGDI_02775 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KEFIEGDI_02776 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
KEFIEGDI_02777 3.5e-76 yhjR S Rubrerythrin
KEFIEGDI_02778 2.4e-13 yhjQ C COG1145 Ferredoxin
KEFIEGDI_02779 0.0 S Sugar transport-related sRNA regulator N-term
KEFIEGDI_02780 1.1e-212 EGP Transmembrane secretion effector
KEFIEGDI_02781 5.1e-199 abrB S membrane
KEFIEGDI_02783 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KEFIEGDI_02784 1.7e-75 yphP S Belongs to the UPF0403 family
KEFIEGDI_02785 1.3e-142 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
KEFIEGDI_02786 9.5e-112 ypjP S YpjP-like protein
KEFIEGDI_02787 7.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
KEFIEGDI_02788 4.8e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KEFIEGDI_02789 1.4e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KEFIEGDI_02790 4.2e-110 hlyIII S protein, Hemolysin III
KEFIEGDI_02791 8.9e-184 pspF K Transcriptional regulator
KEFIEGDI_02792 9.7e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KEFIEGDI_02793 3.1e-40 ypmP S Protein of unknown function (DUF2535)
KEFIEGDI_02794 4.8e-105 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
KEFIEGDI_02795 2.8e-137 ypmR E GDSL-like Lipase/Acylhydrolase
KEFIEGDI_02796 3.2e-98 ypmS S protein conserved in bacteria
KEFIEGDI_02797 1.2e-28 ypmT S Uncharacterized ympT
KEFIEGDI_02798 1.9e-221 mepA V MATE efflux family protein
KEFIEGDI_02799 1.6e-70 ypoP K transcriptional
KEFIEGDI_02800 1.7e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KEFIEGDI_02801 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KEFIEGDI_02802 1.9e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
KEFIEGDI_02803 1.6e-208 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
KEFIEGDI_02804 6.5e-176 cgeB S Spore maturation protein
KEFIEGDI_02805 8.2e-64 cgeA
KEFIEGDI_02806 2.9e-37 cgeC
KEFIEGDI_02807 3.4e-252 cgeD M maturation of the outermost layer of the spore
KEFIEGDI_02808 7.8e-143 yiiD K acetyltransferase
KEFIEGDI_02810 2.4e-245 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KEFIEGDI_02811 2.3e-122 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KEFIEGDI_02812 1.8e-116 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KEFIEGDI_02813 7.9e-257 yodQ 3.5.1.16 E Acetylornithine deacetylase
KEFIEGDI_02814 2e-152 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
KEFIEGDI_02815 2.4e-275 kamA 5.4.3.2 E lysine 2,3-aminomutase
KEFIEGDI_02816 2.9e-47 yokU S YokU-like protein, putative antitoxin
KEFIEGDI_02817 1.4e-36 yozE S Belongs to the UPF0346 family
KEFIEGDI_02818 6e-123 yodN
KEFIEGDI_02820 2.8e-24 yozD S YozD-like protein
KEFIEGDI_02821 4.6e-106 yodM 3.6.1.27 I Acid phosphatase homologues
KEFIEGDI_02822 3.6e-54 yodL S YodL-like
KEFIEGDI_02823 5.3e-09
KEFIEGDI_02824 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
KEFIEGDI_02825 2.1e-138 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KEFIEGDI_02826 2e-23 yodI
KEFIEGDI_02827 2.4e-127 yodH Q Methyltransferase
KEFIEGDI_02828 9.1e-251 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
KEFIEGDI_02829 1.4e-257 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KEFIEGDI_02830 6.2e-28 S Protein of unknown function (DUF3311)
KEFIEGDI_02831 6e-171 yodE E COG0346 Lactoylglutathione lyase and related lyases
KEFIEGDI_02832 3.8e-113 mhqD S Carboxylesterase
KEFIEGDI_02833 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
KEFIEGDI_02834 1.4e-45 L transposase activity
KEFIEGDI_02835 1.4e-107 yodC C nitroreductase
KEFIEGDI_02836 4.4e-55 yodB K transcriptional
KEFIEGDI_02837 9.2e-89 stoA CO thiol-disulfide
KEFIEGDI_02838 1.3e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KEFIEGDI_02839 2.7e-101 ykvT 3.5.1.28 M Cell Wall Hydrolase
KEFIEGDI_02840 2.8e-28
KEFIEGDI_02841 6e-25 ykvS S protein conserved in bacteria
KEFIEGDI_02842 1.1e-44 ykvR S Protein of unknown function (DUF3219)
KEFIEGDI_02843 5.4e-33 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KEFIEGDI_02844 7.8e-91 L Belongs to the 'phage' integrase family
KEFIEGDI_02845 2.4e-41
KEFIEGDI_02846 1.9e-248 I Pfam Lipase (class 3)
KEFIEGDI_02847 3e-28 S Protein of unknown function (DUF1433)
KEFIEGDI_02848 5.8e-48 S Protein of unknown function (DUF1433)
KEFIEGDI_02851 1.9e-44 M D-alanyl-D-alanine carboxypeptidase
KEFIEGDI_02853 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KEFIEGDI_02854 2.4e-138 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KEFIEGDI_02855 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
KEFIEGDI_02856 6.2e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KEFIEGDI_02857 1.2e-178 ykvI S membrane
KEFIEGDI_02858 0.0 clpE O Belongs to the ClpA ClpB family
KEFIEGDI_02859 5.1e-137 motA N flagellar motor
KEFIEGDI_02860 1.5e-122 motB N Flagellar motor protein
KEFIEGDI_02861 1.3e-75 ykvE K transcriptional
KEFIEGDI_02862 6.9e-273 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
KEFIEGDI_02863 1.5e-63 eag
KEFIEGDI_02864 6.4e-09 S Spo0E like sporulation regulatory protein
KEFIEGDI_02865 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
KEFIEGDI_02866 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KEFIEGDI_02867 1.8e-113 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
KEFIEGDI_02868 2.7e-134 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KEFIEGDI_02869 1.3e-229 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
KEFIEGDI_02870 6.8e-231 mtnE 2.6.1.83 E Aminotransferase
KEFIEGDI_02871 3.8e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KEFIEGDI_02872 2.4e-228 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
KEFIEGDI_02873 2.2e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KEFIEGDI_02874 1e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KEFIEGDI_02875 0.0 kinE 2.7.13.3 T Histidine kinase
KEFIEGDI_02876 4.3e-189 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
KEFIEGDI_02877 4.5e-22 ykzE
KEFIEGDI_02878 1.2e-10 ydfR S Protein of unknown function (DUF421)
KEFIEGDI_02879 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
KEFIEGDI_02880 3.5e-155 htpX O Belongs to the peptidase M48B family
KEFIEGDI_02881 1.5e-124 ykrK S Domain of unknown function (DUF1836)
KEFIEGDI_02882 1.9e-26 sspD S small acid-soluble spore protein
KEFIEGDI_02883 1.4e-108 rsgI S Anti-sigma factor N-terminus
KEFIEGDI_02884 1.6e-129 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KEFIEGDI_02886 2.7e-79 dps P Ferritin-like domain
KEFIEGDI_02887 2e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KEFIEGDI_02888 7.2e-301 pepF2 E COG1164 Oligoendopeptidase F
KEFIEGDI_02889 1.2e-63 S YusW-like protein
KEFIEGDI_02890 1e-153 yusV 3.6.3.34 HP ABC transporter
KEFIEGDI_02891 3.8e-47 yusU S Protein of unknown function (DUF2573)
KEFIEGDI_02892 2.8e-157 yusT K LysR substrate binding domain
KEFIEGDI_02893 1e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KEFIEGDI_02894 6e-64 yusQ S Tautomerase enzyme
KEFIEGDI_02895 1.6e-291 yusP P Major facilitator superfamily
KEFIEGDI_02896 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
KEFIEGDI_02897 5.4e-53 yusN M Coat F domain
KEFIEGDI_02898 5.1e-40
KEFIEGDI_02899 2.7e-163 fadM E Proline dehydrogenase
KEFIEGDI_02900 8.1e-09 S YuzL-like protein
KEFIEGDI_02901 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
KEFIEGDI_02902 3.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
KEFIEGDI_02903 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
KEFIEGDI_02904 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
KEFIEGDI_02905 3.5e-64 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
KEFIEGDI_02906 2.4e-39 yusG S Protein of unknown function (DUF2553)
KEFIEGDI_02907 6.3e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
KEFIEGDI_02908 5.6e-55 traF CO Thioredoxin
KEFIEGDI_02909 6e-55 yusD S SCP-2 sterol transfer family
KEFIEGDI_02910 1.4e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KEFIEGDI_02911 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
KEFIEGDI_02912 5.5e-147 metQ P Belongs to the NlpA lipoprotein family
KEFIEGDI_02913 2.3e-47 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KEFIEGDI_02914 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KEFIEGDI_02915 9.1e-245 sufD O assembly protein SufD
KEFIEGDI_02916 7.9e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KEFIEGDI_02917 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
KEFIEGDI_02918 3.5e-271 sufB O FeS cluster assembly
KEFIEGDI_02919 1.1e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
KEFIEGDI_02920 7.9e-64 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KEFIEGDI_02921 1e-41
KEFIEGDI_02923 6.6e-204 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
KEFIEGDI_02924 2.4e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
KEFIEGDI_02925 8.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
KEFIEGDI_02926 1.2e-238 yurO G COG1653 ABC-type sugar transport system, periplasmic component
KEFIEGDI_02927 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
KEFIEGDI_02928 2.1e-147 yurL 2.7.1.218 G pfkB family carbohydrate kinase
KEFIEGDI_02929 4e-133 yurK K UTRA
KEFIEGDI_02930 3.8e-196 msmX P Belongs to the ABC transporter superfamily
KEFIEGDI_02932 3.7e-75 I Fatty acid desaturase
KEFIEGDI_02933 2e-154 ydjN U Involved in the tonB-independent uptake of proteins
KEFIEGDI_02934 4.5e-64 ydjM M Lytic transglycolase
KEFIEGDI_02935 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
KEFIEGDI_02936 8.6e-257 iolT EGP Major facilitator Superfamily
KEFIEGDI_02937 2.3e-117 S Ion transport 2 domain protein
KEFIEGDI_02938 5.2e-141 ydjI S virion core protein (lumpy skin disease virus)
KEFIEGDI_02939 9.7e-130 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
KEFIEGDI_02940 7.5e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KEFIEGDI_02941 1.3e-112 pspA KT Phage shock protein A
KEFIEGDI_02942 1.8e-173 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
KEFIEGDI_02943 1.7e-249 gutA G MFS/sugar transport protein
KEFIEGDI_02944 2.2e-196 gutB 1.1.1.14 E Dehydrogenase
KEFIEGDI_02945 0.0 K NB-ARC domain
KEFIEGDI_02946 1.2e-09 K NB-ARC domain
KEFIEGDI_02947 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
KEFIEGDI_02948 1.5e-98 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
KEFIEGDI_02949 2.3e-287 hsdM 2.1.1.72 V Type I restriction-modification system
KEFIEGDI_02950 3.1e-80 3.1.21.3 V Type I restriction modification DNA specificity domain
KEFIEGDI_02951 5.1e-64 yozB S Membrane
KEFIEGDI_02954 6.3e-236 yobL S Bacterial EndoU nuclease
KEFIEGDI_02955 4.1e-40
KEFIEGDI_02957 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KEFIEGDI_02958 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KEFIEGDI_02959 7.9e-129 ydiL S CAAX protease self-immunity
KEFIEGDI_02960 2.9e-27 ydiK S Domain of unknown function (DUF4305)
KEFIEGDI_02961 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KEFIEGDI_02962 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KEFIEGDI_02963 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KEFIEGDI_02964 7.2e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
KEFIEGDI_02965 0.0 ydiF S ABC transporter
KEFIEGDI_02966 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KEFIEGDI_02967 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KEFIEGDI_02968 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
KEFIEGDI_02969 1.6e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
KEFIEGDI_02970 5.8e-180 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KEFIEGDI_02972 7.8e-08
KEFIEGDI_02973 1.7e-74 yxkC S Domain of unknown function (DUF4352)
KEFIEGDI_02974 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KEFIEGDI_02975 5.8e-222 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KEFIEGDI_02976 3.7e-35 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KEFIEGDI_02977 3.3e-161 lrp QT PucR C-terminal helix-turn-helix domain
KEFIEGDI_02978 5.9e-205 msmK P Belongs to the ABC transporter superfamily
KEFIEGDI_02979 6.2e-154 yxkH G Polysaccharide deacetylase
KEFIEGDI_02981 4.4e-308 3.4.24.84 O Peptidase family M48
KEFIEGDI_02982 1.8e-227 cimH C COG3493 Na citrate symporter
KEFIEGDI_02983 5.3e-267 cydA 1.10.3.14 C oxidase, subunit
KEFIEGDI_02984 8.4e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
KEFIEGDI_02985 8.3e-307 cydD V ATP-binding
KEFIEGDI_02986 0.0 cydD V ATP-binding protein
KEFIEGDI_02987 5e-156 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KEFIEGDI_02988 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
KEFIEGDI_02989 6e-13 sigY K Belongs to the sigma-70 factor family. ECF subfamily
KEFIEGDI_02990 2.5e-39 yxlC S Family of unknown function (DUF5345)
KEFIEGDI_02991 4.9e-28
KEFIEGDI_02992 1.1e-26 yxlE S Phospholipase_D-nuclease N-terminal
KEFIEGDI_02993 1.2e-155 yxlF V ABC transporter, ATP-binding protein
KEFIEGDI_02994 3.8e-134 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KEFIEGDI_02995 8.1e-208 yxlH EGP Major facilitator Superfamily
KEFIEGDI_02996 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KEFIEGDI_02997 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
KEFIEGDI_02998 1.1e-19 yxzF
KEFIEGDI_02999 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
KEFIEGDI_03000 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
KEFIEGDI_03001 8.2e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KEFIEGDI_03002 8.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
KEFIEGDI_03003 1.4e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KEFIEGDI_03004 1.2e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KEFIEGDI_03005 9.6e-138 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
KEFIEGDI_03006 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KEFIEGDI_03007 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEFIEGDI_03008 5.2e-231 dltB M membrane protein involved in D-alanine export
KEFIEGDI_03009 4.1e-289 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEFIEGDI_03011 3.5e-166 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
KEFIEGDI_03012 7.7e-159 yhcP
KEFIEGDI_03013 4.9e-93 yhcQ M Spore coat protein
KEFIEGDI_03014 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
KEFIEGDI_03015 2.1e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
KEFIEGDI_03016 1.1e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KEFIEGDI_03017 9.3e-68 yhcU S Family of unknown function (DUF5365)
KEFIEGDI_03018 9.9e-68 yhcV S COG0517 FOG CBS domain
KEFIEGDI_03019 5.1e-119 yhcW 5.4.2.6 S hydrolase
KEFIEGDI_03020 4.6e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KEFIEGDI_03021 5.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KEFIEGDI_03022 1.2e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KEFIEGDI_03023 2.2e-151 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
KEFIEGDI_03024 5e-292 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KEFIEGDI_03025 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KEFIEGDI_03026 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
KEFIEGDI_03027 2.3e-212 yhcY 2.7.13.3 T Histidine kinase
KEFIEGDI_03028 9.4e-110 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KEFIEGDI_03029 1.2e-83 azr 1.7.1.6 S NADPH-dependent FMN reductase
KEFIEGDI_03030 1.2e-38 yhdB S YhdB-like protein
KEFIEGDI_03031 1.8e-53 yhdC S Protein of unknown function (DUF3889)
KEFIEGDI_03032 4.8e-186 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KEFIEGDI_03033 4.3e-74 nsrR K Transcriptional regulator
KEFIEGDI_03034 7.6e-235 ygxB M Conserved TM helix
KEFIEGDI_03035 6.3e-276 ycgB S Stage V sporulation protein R
KEFIEGDI_03036 2e-255 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
KEFIEGDI_03037 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KEFIEGDI_03038 6.4e-162 citR K Transcriptional regulator
KEFIEGDI_03039 5.9e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
KEFIEGDI_03040 2.8e-79 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEFIEGDI_03041 6.5e-66 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEFIEGDI_03042 3.4e-250 yhdG E amino acid
KEFIEGDI_03043 3.7e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KEFIEGDI_03044 9.1e-267 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KEFIEGDI_03045 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KEFIEGDI_03046 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KEFIEGDI_03047 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KEFIEGDI_03048 4.1e-30 yazB K transcriptional
KEFIEGDI_03049 6.7e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KEFIEGDI_03050 3.8e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KEFIEGDI_03051 1.4e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KEFIEGDI_03052 2.8e-165 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
KEFIEGDI_03053 1.6e-105 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
KEFIEGDI_03054 4.8e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KEFIEGDI_03055 5.7e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KEFIEGDI_03056 2.3e-159 yacD 5.2.1.8 O peptidyl-prolyl isomerase
KEFIEGDI_03057 8.4e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KEFIEGDI_03058 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KEFIEGDI_03059 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KEFIEGDI_03060 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KEFIEGDI_03061 2.5e-272 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KEFIEGDI_03062 3.7e-185 KLT serine threonine protein kinase
KEFIEGDI_03063 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
KEFIEGDI_03064 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
KEFIEGDI_03067 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
KEFIEGDI_03068 1.1e-44 divIC D Septum formation initiator
KEFIEGDI_03069 4.4e-104 yabQ S spore cortex biosynthesis protein
KEFIEGDI_03070 1.5e-49 yabP S Sporulation protein YabP
KEFIEGDI_03071 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KEFIEGDI_03072 1.9e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
KEFIEGDI_03073 1.2e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KEFIEGDI_03074 1.5e-92 spoVT K stage V sporulation protein
KEFIEGDI_03075 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KEFIEGDI_03076 2.4e-39 yabK S Peptide ABC transporter permease
KEFIEGDI_03077 2.3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KEFIEGDI_03078 1.9e-88 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KEFIEGDI_03079 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KEFIEGDI_03080 3.6e-228 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KEFIEGDI_03081 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
KEFIEGDI_03082 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
KEFIEGDI_03083 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
KEFIEGDI_03084 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KEFIEGDI_03085 8.3e-27 sspF S DNA topological change
KEFIEGDI_03086 7.8e-39 veg S protein conserved in bacteria
KEFIEGDI_03087 2.1e-76 dps P Belongs to the Dps family
KEFIEGDI_03089 1.1e-72 ytkA S YtkA-like
KEFIEGDI_03090 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KEFIEGDI_03091 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
KEFIEGDI_03092 6.1e-41 rpmE2 J Ribosomal protein L31
KEFIEGDI_03093 3.1e-248 cydA 1.10.3.14 C oxidase, subunit
KEFIEGDI_03094 8.9e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
KEFIEGDI_03095 4.3e-24 S Domain of Unknown Function (DUF1540)
KEFIEGDI_03096 6.3e-149 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
KEFIEGDI_03097 1.2e-228 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KEFIEGDI_03098 1e-136 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KEFIEGDI_03099 4.8e-168 troA P Belongs to the bacterial solute-binding protein 9 family
KEFIEGDI_03100 2.7e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
KEFIEGDI_03101 1.8e-270 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KEFIEGDI_03102 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KEFIEGDI_03103 2.4e-150 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
KEFIEGDI_03104 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KEFIEGDI_03105 1.2e-271 menF 5.4.4.2 HQ Isochorismate synthase
KEFIEGDI_03106 7.4e-132 dksA T COG1734 DnaK suppressor protein
KEFIEGDI_03107 2.1e-151 galU 2.7.7.9 M Nucleotidyl transferase
KEFIEGDI_03108 2.2e-243 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KEFIEGDI_03109 2e-177 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
KEFIEGDI_03110 8.2e-232 ytcC M Glycosyltransferase Family 4
KEFIEGDI_03112 2.5e-205 cotS S Seems to be required for the assembly of the CotSA protein in spores
KEFIEGDI_03113 3.2e-214 cotSA M Glycosyl transferases group 1
KEFIEGDI_03114 1.3e-204 cotI S Spore coat protein
KEFIEGDI_03115 1.4e-34 tspO T membrane
KEFIEGDI_03116 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KEFIEGDI_03117 3.3e-280 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
KEFIEGDI_03118 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
KEFIEGDI_03119 2.6e-195 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KEFIEGDI_03120 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KEFIEGDI_03129 7.8e-08
KEFIEGDI_03130 1.3e-09
KEFIEGDI_03137 2e-08
KEFIEGDI_03142 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KEFIEGDI_03143 2.1e-219 yeaN P COG2807 Cyanate permease
KEFIEGDI_03144 1.9e-15 yycC K YycC-like protein
KEFIEGDI_03146 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
KEFIEGDI_03147 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KEFIEGDI_03148 1.9e-74 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KEFIEGDI_03149 3.3e-247 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KEFIEGDI_03154 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEFIEGDI_03155 0.0 vicK 2.7.13.3 T Histidine kinase
KEFIEGDI_03156 4.4e-258 yycH S protein conserved in bacteria
KEFIEGDI_03157 3.6e-154 yycI S protein conserved in bacteria
KEFIEGDI_03158 7.4e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
KEFIEGDI_03159 2.5e-217 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KEFIEGDI_03160 1.9e-33 S Peptidase propeptide and YPEB domain
KEFIEGDI_03161 4e-74 S Peptidase propeptide and YPEB domain
KEFIEGDI_03162 7.6e-94 K PFAM response regulator receiver
KEFIEGDI_03163 7.4e-171 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
KEFIEGDI_03164 3.4e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KEFIEGDI_03165 2.6e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
KEFIEGDI_03166 2.8e-260 rocE E amino acid
KEFIEGDI_03167 5.2e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
KEFIEGDI_03169 1.5e-187 S aspartate phosphatase
KEFIEGDI_03170 1.9e-83 yycN 2.3.1.128 K Acetyltransferase
KEFIEGDI_03171 2.1e-129 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KEFIEGDI_03172 8.1e-205 yycP
KEFIEGDI_03173 1.3e-30 yycQ S Protein of unknown function (DUF2651)
KEFIEGDI_03175 1.3e-232 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KEFIEGDI_03176 1.8e-66
KEFIEGDI_03177 1.1e-09 S YyzF-like protein
KEFIEGDI_03178 2.6e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KEFIEGDI_03179 1.1e-34 L Protein of unknown function (DUF2813)
KEFIEGDI_03180 3.7e-172 L Protein of unknown function (DUF2813)
KEFIEGDI_03181 1.8e-17 pcrA1 3.6.4.12 L UvrD/REP helicase N-terminal domain
KEFIEGDI_03182 2.3e-134 pcrA1 3.6.4.12 L UvrD/REP helicase N-terminal domain
KEFIEGDI_03183 4.8e-111 yyaC S Sporulation protein YyaC
KEFIEGDI_03184 1.8e-176 yyaD S Membrane
KEFIEGDI_03185 2.3e-33 yyzM S protein conserved in bacteria
KEFIEGDI_03186 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KEFIEGDI_03187 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KEFIEGDI_03188 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
KEFIEGDI_03189 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KEFIEGDI_03190 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KEFIEGDI_03191 1.7e-142 xth 3.1.11.2 L exodeoxyribonuclease III
KEFIEGDI_03192 3.6e-179 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
KEFIEGDI_03193 4.6e-64 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KEFIEGDI_03194 2.4e-93 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
KEFIEGDI_03195 1.5e-242 EGP Major facilitator superfamily
KEFIEGDI_03196 8.9e-167 yyaK S CAAX protease self-immunity
KEFIEGDI_03197 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
KEFIEGDI_03198 6.7e-104 yyaP 1.5.1.3 H RibD C-terminal domain
KEFIEGDI_03199 2.8e-37 yyaQ S YjbR
KEFIEGDI_03200 4.5e-94 yyaR K Acetyltransferase (GNAT) domain
KEFIEGDI_03201 6.5e-97 yyaS S Membrane
KEFIEGDI_03202 1e-67 yjcF S Acetyltransferase (GNAT) domain
KEFIEGDI_03203 5.6e-77 yybA 2.3.1.57 K transcriptional
KEFIEGDI_03204 3.4e-100 S Metallo-beta-lactamase superfamily
KEFIEGDI_03205 1.9e-49 gloA_3 E COG0346 Lactoylglutathione lyase and related lyases
KEFIEGDI_03206 1.4e-85 E LysE type translocator
KEFIEGDI_03207 9.4e-145 yfiE K LysR substrate binding domain
KEFIEGDI_03208 9e-31 yybC
KEFIEGDI_03209 7.2e-77 yjcF S Acetyltransferase (GNAT) domain
KEFIEGDI_03210 1.2e-160 yybE K Transcriptional regulator
KEFIEGDI_03211 3.4e-214 ynfM EGP Major facilitator Superfamily
KEFIEGDI_03212 1.3e-102 yybG S Pentapeptide repeat-containing protein
KEFIEGDI_03213 2.5e-65 yybH S SnoaL-like domain
KEFIEGDI_03214 1.6e-124
KEFIEGDI_03215 7.7e-105 K TipAS antibiotic-recognition domain
KEFIEGDI_03216 3.9e-240 yybO G COG0477 Permeases of the major facilitator superfamily
KEFIEGDI_03218 7.3e-61
KEFIEGDI_03219 5.6e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
KEFIEGDI_03220 1.7e-66 ydeP3 K Transcriptional regulator
KEFIEGDI_03221 4.4e-52 cotF M Spore coat protein
KEFIEGDI_03222 4e-14 cotF M Spore coat protein
KEFIEGDI_03224 3.2e-159 yybS S membrane
KEFIEGDI_03225 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KEFIEGDI_03226 2.2e-73 rplI J binds to the 23S rRNA
KEFIEGDI_03227 8.1e-88 yhjH K helix_turn_helix multiple antibiotic resistance protein
KEFIEGDI_03228 5.8e-269 yhjG CH FAD binding domain
KEFIEGDI_03229 3.4e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
KEFIEGDI_03230 3.4e-109 yhjE S SNARE associated Golgi protein
KEFIEGDI_03231 3.6e-58 yhjD
KEFIEGDI_03232 5.8e-26 yhjC S Protein of unknown function (DUF3311)
KEFIEGDI_03233 1.2e-264 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KEFIEGDI_03234 3.9e-41 yhjA S Excalibur calcium-binding domain
KEFIEGDI_03235 2.4e-164 IQ Enoyl-(Acyl carrier protein) reductase
KEFIEGDI_03236 4.2e-109 comK K Competence transcription factor
KEFIEGDI_03237 1.3e-32 yhzC S IDEAL
KEFIEGDI_03238 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEFIEGDI_03239 2.7e-188 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
KEFIEGDI_03240 2.2e-90 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
KEFIEGDI_03241 1.4e-181 hemAT NT chemotaxis protein
KEFIEGDI_03242 1.1e-90 bioY S BioY family
KEFIEGDI_03243 1.4e-270 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
KEFIEGDI_03244 7.7e-197 vraB 2.3.1.9 I Belongs to the thiolase family
KEFIEGDI_03245 7.1e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
KEFIEGDI_03246 4.5e-156 yfmC M Periplasmic binding protein
KEFIEGDI_03247 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
KEFIEGDI_03248 4e-75 VY92_01935 K acetyltransferase
KEFIEGDI_03249 3.4e-203 aprE 3.4.21.62 O Belongs to the peptidase S8 family
KEFIEGDI_03250 3.6e-238 yhfN 3.4.24.84 O Peptidase M48
KEFIEGDI_03251 5.6e-65 yhfM
KEFIEGDI_03252 1.6e-299 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
KEFIEGDI_03253 2.2e-111 yhfK GM NmrA-like family
KEFIEGDI_03254 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
KEFIEGDI_03255 3.4e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
KEFIEGDI_03256 1.4e-226 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KEFIEGDI_03257 1.9e-71 3.4.13.21 S ASCH
KEFIEGDI_03258 2.3e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
KEFIEGDI_03259 1.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
KEFIEGDI_03260 3.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KEFIEGDI_03261 3.3e-213 yhgE S YhgE Pip N-terminal domain protein
KEFIEGDI_03262 4.6e-100 yhgD K Transcriptional regulator
KEFIEGDI_03263 4.9e-53 yneQ
KEFIEGDI_03264 1.2e-73 yneP S Thioesterase-like superfamily
KEFIEGDI_03265 1.1e-34 tlp S Belongs to the Tlp family
KEFIEGDI_03266 3.1e-08 sspN S Small acid-soluble spore protein N family
KEFIEGDI_03268 6.5e-90 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KEFIEGDI_03269 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KEFIEGDI_03270 2.2e-14 sspO S Belongs to the SspO family
KEFIEGDI_03271 3.9e-19 sspP S Belongs to the SspP family
KEFIEGDI_03272 5.9e-64 hspX O Spore coat protein
KEFIEGDI_03273 7.2e-74 yneK S Protein of unknown function (DUF2621)
KEFIEGDI_03274 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
KEFIEGDI_03275 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
KEFIEGDI_03276 7.1e-127 ccdA O cytochrome c biogenesis protein
KEFIEGDI_03277 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
KEFIEGDI_03278 1.8e-28 yneF S UPF0154 protein
KEFIEGDI_03279 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
KEFIEGDI_03280 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KEFIEGDI_03281 4.8e-32 ynzC S UPF0291 protein
KEFIEGDI_03282 3.6e-109 yneB L resolvase
KEFIEGDI_03283 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
KEFIEGDI_03284 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KEFIEGDI_03285 4.9e-78 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
KEFIEGDI_03286 2.1e-91 yndM S Protein of unknown function (DUF2512)
KEFIEGDI_03287 6.8e-136 yndL S Replication protein
KEFIEGDI_03289 1e-301 yndJ S YndJ-like protein
KEFIEGDI_03290 3.2e-115 yndH S Domain of unknown function (DUF4166)
KEFIEGDI_03291 8.9e-110 yndG S DoxX-like family
KEFIEGDI_03292 9.7e-179 gerLC S Spore germination protein
KEFIEGDI_03293 1.9e-164 gerAB U Spore germination
KEFIEGDI_03295 3.1e-71
KEFIEGDI_03296 7.9e-25 tatA U protein secretion
KEFIEGDI_03299 3.9e-125 S Domain of unknown function, YrpD
KEFIEGDI_03301 1.2e-162 S Thymidylate synthase
KEFIEGDI_03302 2.5e-09 V VanZ like family
KEFIEGDI_03303 1.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
KEFIEGDI_03304 1.7e-46 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KEFIEGDI_03305 2.2e-61 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KEFIEGDI_03306 3.9e-66 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KEFIEGDI_03307 4.4e-253 iolT EGP Major facilitator Superfamily
KEFIEGDI_03308 6.2e-79 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
KEFIEGDI_03309 4.8e-114 ynaE S Domain of unknown function (DUF3885)
KEFIEGDI_03310 1.7e-75 ynaD J Acetyltransferase (GNAT) domain
KEFIEGDI_03311 7.2e-39 splA S Transcriptional regulator
KEFIEGDI_03312 1.3e-201 splB 4.1.99.14 L Spore photoproduct lyase
KEFIEGDI_03313 1.6e-126 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KEFIEGDI_03314 2.4e-257 mcpC NT chemotaxis protein
KEFIEGDI_03315 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
KEFIEGDI_03316 3e-123 ykwD J protein with SCP PR1 domains
KEFIEGDI_03317 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
KEFIEGDI_03318 0.0 pilS 2.7.13.3 T Histidine kinase
KEFIEGDI_03319 2.6e-219 patA 2.6.1.1 E Aminotransferase
KEFIEGDI_03320 2.2e-15
KEFIEGDI_03321 2.4e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
KEFIEGDI_03322 1.7e-84 ykyB S YkyB-like protein
KEFIEGDI_03323 1.1e-237 ykuC EGP Major facilitator Superfamily
KEFIEGDI_03324 9.4e-166 ykuE S Metallophosphoesterase
KEFIEGDI_03325 3.2e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEFIEGDI_03326 0.0 3.2.1.132 M Putative peptidoglycan binding domain
KEFIEGDI_03328 4.4e-233 ykuI T Diguanylate phosphodiesterase
KEFIEGDI_03329 3.9e-37 ykuJ S protein conserved in bacteria
KEFIEGDI_03330 4.4e-94 ykuK S Ribonuclease H-like
KEFIEGDI_03331 3.9e-27 ykzF S Antirepressor AbbA
KEFIEGDI_03332 1.4e-75 ykuL S CBS domain
KEFIEGDI_03333 3.5e-168 ccpC K Transcriptional regulator
KEFIEGDI_03334 4.5e-85 fld C Flavodoxin domain
KEFIEGDI_03335 6.3e-173 ykuO
KEFIEGDI_03336 1.1e-77 fld C Flavodoxin
KEFIEGDI_03337 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KEFIEGDI_03338 1.2e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KEFIEGDI_03339 9e-37 ykuS S Belongs to the UPF0180 family
KEFIEGDI_03340 8.8e-142 ykuT M Mechanosensitive ion channel
KEFIEGDI_03341 1.1e-100 ykuU O Alkyl hydroperoxide reductase
KEFIEGDI_03342 8.5e-75 ykuV CO thiol-disulfide
KEFIEGDI_03343 1.5e-93 rok K Repressor of ComK
KEFIEGDI_03344 1.9e-146 yjbA S Belongs to the UPF0736 family
KEFIEGDI_03345 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KEFIEGDI_03346 2e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KEFIEGDI_03347 4e-250 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
KEFIEGDI_03348 3e-184 appF E Belongs to the ABC transporter superfamily
KEFIEGDI_03349 1.8e-184 appD P Belongs to the ABC transporter superfamily
KEFIEGDI_03350 2.5e-149 yjaZ O Zn-dependent protease
KEFIEGDI_03351 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KEFIEGDI_03352 8.7e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KEFIEGDI_03353 1.1e-20 yjzB
KEFIEGDI_03354 7.3e-26 comZ S ComZ
KEFIEGDI_03355 4.2e-183 med S Transcriptional activator protein med
KEFIEGDI_03356 3.8e-99 yjaV
KEFIEGDI_03357 6.8e-141 yjaU I carboxylic ester hydrolase activity
KEFIEGDI_03358 2.3e-16 yjzD S Protein of unknown function (DUF2929)
KEFIEGDI_03359 9.5e-28 yjzC S YjzC-like protein
KEFIEGDI_03360 1.4e-173 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KEFIEGDI_03361 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
KEFIEGDI_03362 2.6e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KEFIEGDI_03363 2.4e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
KEFIEGDI_03364 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KEFIEGDI_03365 1e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KEFIEGDI_03366 1.2e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KEFIEGDI_03367 1.7e-88 norB G Major Facilitator Superfamily
KEFIEGDI_03368 1.4e-217 yitY C D-arabinono-1,4-lactone oxidase
KEFIEGDI_03369 7.6e-40 yitY C D-arabinono-1,4-lactone oxidase
KEFIEGDI_03370 1.1e-22 pilT S Proteolipid membrane potential modulator
KEFIEGDI_03371 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
KEFIEGDI_03372 1.1e-141 yjfP S COG1073 Hydrolases of the alpha beta superfamily
KEFIEGDI_03373 6e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
KEFIEGDI_03375 1.5e-26 S Protein of unknown function (DUF3813)
KEFIEGDI_03376 5e-73 ipi S Intracellular proteinase inhibitor
KEFIEGDI_03377 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
KEFIEGDI_03378 7.9e-157 yitS S protein conserved in bacteria
KEFIEGDI_03379 9e-36 yitR S Domain of unknown function (DUF3784)
KEFIEGDI_03381 1.4e-34 ydjO S Cold-inducible protein YdjO
KEFIEGDI_03382 1.3e-156 ydjP I Alpha/beta hydrolase family
KEFIEGDI_03383 2.2e-79 yeaA S Protein of unknown function (DUF4003)
KEFIEGDI_03384 9.3e-30 yeaA S Protein of unknown function (DUF4003)
KEFIEGDI_03385 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
KEFIEGDI_03386 6.3e-252 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
KEFIEGDI_03387 3.5e-152 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KEFIEGDI_03388 2.8e-174 yeaC S COG0714 MoxR-like ATPases
KEFIEGDI_03389 1.9e-220 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
KEFIEGDI_03390 0.0 yebA E COG1305 Transglutaminase-like enzymes
KEFIEGDI_03391 3.7e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KEFIEGDI_03392 3.3e-210 pbuG S permease
KEFIEGDI_03393 2.3e-118 yebC M Membrane
KEFIEGDI_03395 4e-93 yebE S UPF0316 protein
KEFIEGDI_03396 8e-28 yebG S NETI protein
KEFIEGDI_03397 1.4e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KEFIEGDI_03398 8.5e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KEFIEGDI_03399 2.1e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KEFIEGDI_03400 2.4e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KEFIEGDI_03401 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KEFIEGDI_03402 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KEFIEGDI_03403 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KEFIEGDI_03404 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KEFIEGDI_03405 3.2e-176 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KEFIEGDI_03406 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KEFIEGDI_03407 1.7e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KEFIEGDI_03408 7.7e-233 purD 6.3.4.13 F Belongs to the GARS family
KEFIEGDI_03411 1.2e-16 ydhU P Manganese containing catalase
KEFIEGDI_03412 5.6e-90 ydhU P Catalase
KEFIEGDI_03413 1e-102 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
KEFIEGDI_03414 1.1e-39 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
KEFIEGDI_03415 5.6e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
KEFIEGDI_03416 8.9e-167 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
KEFIEGDI_03417 4.3e-132 ydhQ K UTRA
KEFIEGDI_03418 3.6e-284 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KEFIEGDI_03419 3.7e-238 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KEFIEGDI_03420 4.3e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
KEFIEGDI_03421 1.2e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
KEFIEGDI_03422 1.8e-199 pbuE EGP Major facilitator Superfamily
KEFIEGDI_03423 2e-95 ydhK M Protein of unknown function (DUF1541)
KEFIEGDI_03424 1e-179 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
KEFIEGDI_03425 3.3e-83 K Acetyltransferase (GNAT) domain
KEFIEGDI_03427 2.1e-66 frataxin S Domain of unknown function (DU1801)
KEFIEGDI_03428 2.9e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
KEFIEGDI_03429 1.1e-122
KEFIEGDI_03430 1.3e-224 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KEFIEGDI_03431 2e-241 ydhD M Glycosyl hydrolase
KEFIEGDI_03432 6.5e-122 ydhC K FCD
KEFIEGDI_03433 1e-120 ydhB S membrane transporter protein
KEFIEGDI_03434 1.4e-207 tcaB EGP Major facilitator Superfamily
KEFIEGDI_03435 3.5e-68 ydgJ K Winged helix DNA-binding domain
KEFIEGDI_03436 3e-113 drgA C nitroreductase
KEFIEGDI_03437 0.0 ydgH S drug exporters of the RND superfamily
KEFIEGDI_03438 2e-78 K helix_turn_helix multiple antibiotic resistance protein
KEFIEGDI_03439 1.1e-87 dinB S DinB family
KEFIEGDI_03440 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
KEFIEGDI_03441 3.5e-54 expZ S ABC transporter
KEFIEGDI_03442 1.6e-49 K Bacterial regulatory proteins, tetR family
KEFIEGDI_03443 3.8e-52
KEFIEGDI_03444 8.2e-30
KEFIEGDI_03447 3.1e-57
KEFIEGDI_03448 2.1e-62
KEFIEGDI_03449 4e-123 xerH L Belongs to the 'phage' integrase family
KEFIEGDI_03451 1e-20
KEFIEGDI_03452 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KEFIEGDI_03453 1.2e-84 S Phage tail protein
KEFIEGDI_03454 7.5e-307 S Pfam Transposase IS66
KEFIEGDI_03455 1.7e-83
KEFIEGDI_03456 1.2e-55 S outer membrane
KEFIEGDI_03457 8.3e-175 S N-acetylmuramoyl-L-alanine amidase activity
KEFIEGDI_03459 7.8e-36 S Bacteriophage holin
KEFIEGDI_03460 8.6e-204 S aspartate phosphatase
KEFIEGDI_03462 2.8e-235 S impB/mucB/samB family C-terminal domain
KEFIEGDI_03463 1.6e-52 S YolD-like protein
KEFIEGDI_03464 3e-32
KEFIEGDI_03465 0.0 K Psort location Cytoplasmic, score
KEFIEGDI_03466 3.3e-85 S SMI1-KNR4 cell-wall
KEFIEGDI_03467 1.2e-100 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KEFIEGDI_03468 4e-153 sacY K transcriptional antiterminator
KEFIEGDI_03469 2.9e-241 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KEFIEGDI_03470 5.4e-270 epr 3.4.21.62 O Belongs to the peptidase S8 family
KEFIEGDI_03471 2.3e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KEFIEGDI_03472 4.4e-67 ywbC 4.4.1.5 E glyoxalase
KEFIEGDI_03473 2.7e-219 ywbD 2.1.1.191 J Methyltransferase
KEFIEGDI_03474 2.3e-27 ywbE S Uncharacterized conserved protein (DUF2196)
KEFIEGDI_03475 4.5e-132 ywbF EGP Major facilitator Superfamily
KEFIEGDI_03476 5.9e-54 ywbF EGP Major facilitator Superfamily
KEFIEGDI_03477 2.3e-111 ywbG M effector of murein hydrolase
KEFIEGDI_03478 1.9e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
KEFIEGDI_03479 4.3e-153 ywbI K Transcriptional regulator
KEFIEGDI_03480 1.1e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KEFIEGDI_03481 5.5e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KEFIEGDI_03482 1.7e-112 P COG0672 High-affinity Fe2 Pb2 permease
KEFIEGDI_03483 5.5e-119 P COG0672 High-affinity Fe2 Pb2 permease
KEFIEGDI_03484 3.2e-185 ycdO P periplasmic lipoprotein involved in iron transport
KEFIEGDI_03485 2.5e-223 ywbN P Dyp-type peroxidase family protein
KEFIEGDI_03486 4.4e-109 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KEFIEGDI_03487 5.3e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KEFIEGDI_03488 4.9e-48 ywcB S Protein of unknown function, DUF485
KEFIEGDI_03490 4.7e-120 ywcC K transcriptional regulator
KEFIEGDI_03491 4.7e-59 gtcA S GtrA-like protein
KEFIEGDI_03492 4e-228 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KEFIEGDI_03493 2.8e-301 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KEFIEGDI_03494 1e-35 ywzA S membrane
KEFIEGDI_03495 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
KEFIEGDI_03496 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KEFIEGDI_03497 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KEFIEGDI_03498 1.5e-62 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KEFIEGDI_03499 1e-72 K helix_turn_helix ASNC type
KEFIEGDI_03500 1.8e-226 yjeH E Amino acid permease
KEFIEGDI_03501 2.7e-27 S Protein of unknown function (DUF2892)
KEFIEGDI_03502 0.0 yerA 3.5.4.2 F adenine deaminase
KEFIEGDI_03503 1.6e-188 yerB S Protein of unknown function (DUF3048) C-terminal domain
KEFIEGDI_03504 4.8e-51 yerC S protein conserved in bacteria
KEFIEGDI_03505 2.1e-144 yerD 1.4.7.1 E Belongs to the glutamate synthase family
KEFIEGDI_03506 3.1e-75 yerD 1.4.7.1 E Belongs to the glutamate synthase family
KEFIEGDI_03508 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KEFIEGDI_03509 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KEFIEGDI_03510 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KEFIEGDI_03511 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
KEFIEGDI_03512 1.9e-194 yerI S homoserine kinase type II (protein kinase fold)
KEFIEGDI_03513 1.6e-123 sapB S MgtC SapB transporter
KEFIEGDI_03514 2.1e-261 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KEFIEGDI_03515 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KEFIEGDI_03516 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KEFIEGDI_03517 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KEFIEGDI_03518 3.7e-146 yerO K Transcriptional regulator
KEFIEGDI_03519 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KEFIEGDI_03520 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KEFIEGDI_03521 1.4e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KEFIEGDI_03522 2.1e-153 haeIIIM 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
KEFIEGDI_03523 2.1e-108 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KEFIEGDI_03524 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
KEFIEGDI_03525 0.0 yojO P Von Willebrand factor
KEFIEGDI_03526 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
KEFIEGDI_03527 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
KEFIEGDI_03528 8.6e-168 yocS S -transporter
KEFIEGDI_03529 3.8e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KEFIEGDI_03530 6.6e-164 sodA 1.15.1.1 P Superoxide dismutase
KEFIEGDI_03531 1.3e-112 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
KEFIEGDI_03532 3.3e-200 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
KEFIEGDI_03533 2e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
KEFIEGDI_03534 2.7e-31 yozC
KEFIEGDI_03535 4.2e-56 yozO S Bacterial PH domain
KEFIEGDI_03536 1.9e-36 yocN
KEFIEGDI_03537 1.1e-40 yozN
KEFIEGDI_03538 3.8e-81 yocM O Belongs to the small heat shock protein (HSP20) family
KEFIEGDI_03539 1.4e-31
KEFIEGDI_03540 8.4e-54 yocL
KEFIEGDI_03541 8.2e-82 dksA T general stress protein
KEFIEGDI_03542 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KEFIEGDI_03543 0.0 recQ 3.6.4.12 L DNA helicase
KEFIEGDI_03544 6e-112 yocH CBM50 M COG1388 FOG LysM repeat
KEFIEGDI_03545 2.9e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KEFIEGDI_03546 1e-196 desK 2.7.13.3 T Histidine kinase
KEFIEGDI_03547 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
KEFIEGDI_03548 1.9e-186 yocD 3.4.17.13 V peptidase S66
KEFIEGDI_03549 1.5e-91 yocC
KEFIEGDI_03550 1.7e-142
KEFIEGDI_03551 1.5e-92 yozB S membrane
KEFIEGDI_03552 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KEFIEGDI_03553 3.3e-175 isp O Belongs to the peptidase S8 family
KEFIEGDI_03554 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KEFIEGDI_03555 2e-135 ykoC P Cobalt transport protein
KEFIEGDI_03556 3.7e-304 P ABC transporter, ATP-binding protein
KEFIEGDI_03557 5.7e-77 ykoE S ABC-type cobalt transport system, permease component
KEFIEGDI_03558 3.3e-109 ykoF S YKOF-related Family
KEFIEGDI_03559 1.1e-28 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEFIEGDI_03560 4.9e-60 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEFIEGDI_03561 1.3e-103 ykoH 2.7.13.3 T Histidine kinase
KEFIEGDI_03562 1.3e-94 ykoH 2.7.13.3 T Histidine kinase
KEFIEGDI_03563 9.9e-110 ykoI S Peptidase propeptide and YPEB domain
KEFIEGDI_03564 1.4e-84 ykoJ S Peptidase propeptide and YPEB domain
KEFIEGDI_03567 1.9e-221 mgtE P Acts as a magnesium transporter
KEFIEGDI_03568 1.4e-53 tnrA K transcriptional
KEFIEGDI_03569 5.9e-18
KEFIEGDI_03570 6.9e-26 ykoL
KEFIEGDI_03571 1.3e-81 mhqR K transcriptional
KEFIEGDI_03572 1.9e-89 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
KEFIEGDI_03573 6.3e-90 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
KEFIEGDI_03574 4.1e-96 ykoP G polysaccharide deacetylase
KEFIEGDI_03575 8.3e-113 ykoQ S Calcineurin-like phosphoesterase superfamily domain
KEFIEGDI_03576 8.1e-23 ykoQ S Calcineurin-like phosphoesterase superfamily domain
KEFIEGDI_03577 0.0 ykoS
KEFIEGDI_03578 3.1e-184 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KEFIEGDI_03579 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
KEFIEGDI_03580 1.4e-159 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KEFIEGDI_03581 1.1e-20 ydcR 2.7.7.65 T Diguanylate cyclase
KEFIEGDI_03582 2.9e-160 ydcR 2.7.7.65 T Diguanylate cyclase
KEFIEGDI_03583 2.1e-66 ydcR 2.7.7.65 T Diguanylate cyclase
KEFIEGDI_03584 1.7e-108 ykoX S membrane-associated protein
KEFIEGDI_03585 5.1e-176 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
KEFIEGDI_03587 1.4e-83
KEFIEGDI_03588 1.7e-282 3.6.4.12 J DnaB-like helicase C terminal domain
KEFIEGDI_03589 1.1e-217 L DNA primase activity
KEFIEGDI_03590 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KEFIEGDI_03591 0.0 S Bacterial DNA polymerase III alpha subunit
KEFIEGDI_03592 4.6e-105 DR0488 S protein conserved in bacteria
KEFIEGDI_03597 1.2e-83 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
KEFIEGDI_03598 2.3e-90 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
KEFIEGDI_03599 5.6e-93 S methyltransferase activity
KEFIEGDI_03600 1.9e-158 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
KEFIEGDI_03604 1.3e-12
KEFIEGDI_03608 1.8e-24 S hydrolase activity
KEFIEGDI_03620 2.2e-61 S NrdI Flavodoxin like
KEFIEGDI_03621 5.6e-206 S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
KEFIEGDI_03622 4.4e-169 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KEFIEGDI_03623 6.8e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KEFIEGDI_03624 3.2e-34 O Glutaredoxin
KEFIEGDI_03625 1.4e-09
KEFIEGDI_03626 2.1e-73 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
KEFIEGDI_03627 6.4e-73 yosT L Bacterial transcription activator, effector binding domain
KEFIEGDI_03632 1.9e-217 naiP P Uncharacterised MFS-type transporter YbfB
KEFIEGDI_03633 2e-203 yceJ EGP Uncharacterised MFS-type transporter YbfB
KEFIEGDI_03634 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
KEFIEGDI_03635 2.5e-228 proV 3.6.3.32 E glycine betaine
KEFIEGDI_03636 1.3e-127 opuAB P glycine betaine
KEFIEGDI_03637 5.3e-164 opuAC E glycine betaine
KEFIEGDI_03638 9.5e-214 amhX S amidohydrolase
KEFIEGDI_03639 5.6e-256 ycgA S Membrane
KEFIEGDI_03640 1.3e-79 ycgB
KEFIEGDI_03641 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
KEFIEGDI_03642 2.8e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KEFIEGDI_03643 4.8e-288 lctP C L-lactate permease
KEFIEGDI_03644 3.9e-263 mdr EGP Major facilitator Superfamily
KEFIEGDI_03645 1.1e-75 emrR K helix_turn_helix multiple antibiotic resistance protein
KEFIEGDI_03646 8.2e-108 ycgF E Lysine exporter protein LysE YggA
KEFIEGDI_03647 3e-79 yqcI S YqcI/YcgG family
KEFIEGDI_03648 3.8e-43 yqcI S YqcI/YcgG family
KEFIEGDI_03649 1.9e-133 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
KEFIEGDI_03650 1.6e-93 ycgI S Domain of unknown function (DUF1989)
KEFIEGDI_03651 4.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KEFIEGDI_03652 3.4e-106 tmrB S AAA domain
KEFIEGDI_03653 6.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KEFIEGDI_03654 1e-116 S nuclease activity
KEFIEGDI_03655 1.2e-52
KEFIEGDI_03656 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KEFIEGDI_03657 2.9e-276 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KEFIEGDI_03658 4.4e-65 yxiE T Belongs to the universal stress protein A family
KEFIEGDI_03659 9.6e-164 yxxF EG EamA-like transporter family
KEFIEGDI_03660 8.3e-305 wapA M COG3209 Rhs family protein
KEFIEGDI_03661 3.6e-52 padR K Transcriptional regulator PadR-like family
KEFIEGDI_03662 1.6e-208 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
KEFIEGDI_03663 9.6e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
KEFIEGDI_03664 3.1e-229 yxiO S COG2270 Permeases of the major facilitator superfamily
KEFIEGDI_03665 2.5e-97
KEFIEGDI_03666 1.7e-148 licT K transcriptional antiterminator
KEFIEGDI_03667 8e-142 exoK GH16 M licheninase activity
KEFIEGDI_03668 9.5e-223 citH C Citrate transporter
KEFIEGDI_03669 5.9e-185 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
KEFIEGDI_03670 3.6e-137 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
KEFIEGDI_03671 3e-47 yxiS
KEFIEGDI_03672 1.2e-102 T Domain of unknown function (DUF4163)
KEFIEGDI_03673 9.5e-209 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KEFIEGDI_03674 3.6e-100 mleA 1.1.1.38 C malic enzyme
KEFIEGDI_03675 5e-233 mleN C Na H antiporter
KEFIEGDI_03676 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
KEFIEGDI_03677 3.3e-183 ansA 3.5.1.1 EJ L-asparaginase
KEFIEGDI_03678 4.5e-58 ansR K Transcriptional regulator
KEFIEGDI_03679 1.5e-222 yqxK 3.6.4.12 L DNA helicase
KEFIEGDI_03680 1.7e-91 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
KEFIEGDI_03682 3.5e-166 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
KEFIEGDI_03684 7.2e-172 yqkD S COG1073 Hydrolases of the alpha beta superfamily
KEFIEGDI_03685 9.4e-39 yqkC S Protein of unknown function (DUF2552)
KEFIEGDI_03686 2.8e-54 yqkB S Belongs to the HesB IscA family
KEFIEGDI_03687 3.5e-191 yqkA K GrpB protein
KEFIEGDI_03688 6.8e-59 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
KEFIEGDI_03689 9e-86 yqjY K acetyltransferase
KEFIEGDI_03690 1.7e-49 S YolD-like protein
KEFIEGDI_03691 9.2e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KEFIEGDI_03693 8.3e-224 yqjV G Major Facilitator Superfamily
KEFIEGDI_03695 7.2e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KEFIEGDI_03696 9.1e-178 coaA 2.7.1.33 F Pantothenic acid kinase
KEFIEGDI_03697 1.6e-257 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
KEFIEGDI_03698 1.3e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
KEFIEGDI_03699 5.4e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
KEFIEGDI_03700 2.3e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KEFIEGDI_03702 1.2e-87 MA20_36670 EGP Major facilitator Superfamily
KEFIEGDI_03703 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
KEFIEGDI_03704 1.4e-105 yrhP E LysE type translocator
KEFIEGDI_03705 2.5e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
KEFIEGDI_03706 0.0 levR K PTS system fructose IIA component
KEFIEGDI_03707 1.1e-74 levD 2.7.1.202 G PTS system fructose IIA component
KEFIEGDI_03708 2.4e-81 levE 2.7.1.202 G PTS system mannose fructose sorbose family
KEFIEGDI_03709 1.1e-115 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
KEFIEGDI_03710 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
KEFIEGDI_03711 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
KEFIEGDI_03712 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
KEFIEGDI_03713 1.1e-195 adhA 1.1.1.1 C alcohol dehydrogenase
KEFIEGDI_03714 3.7e-70 pcaC 4.1.1.44 S conserved protein, contains double-stranded beta-helix domain
KEFIEGDI_03715 1.1e-45 yraB K helix_turn_helix, mercury resistance
KEFIEGDI_03716 3.2e-17 rmeD K MerR family transcriptional regulator
KEFIEGDI_03718 2.3e-114 K Transcriptional regulator
KEFIEGDI_03719 2.6e-164 yajO C Aldo/keto reductase family
KEFIEGDI_03720 8e-13 ptsH G phosphocarrier protein HPr
KEFIEGDI_03721 1.2e-48 yraD M Spore coat protein
KEFIEGDI_03722 2.9e-145 cypA C Cytochrome P450
KEFIEGDI_03724 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
KEFIEGDI_03725 5.9e-109 prrC P ABC transporter
KEFIEGDI_03726 1.6e-118 S ABC-2 family transporter protein
KEFIEGDI_03727 7.6e-13
KEFIEGDI_03728 3.7e-123 yydK K Transcriptional regulator
KEFIEGDI_03729 4.1e-12 bglF G phosphotransferase system
KEFIEGDI_03730 2.7e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KEFIEGDI_03731 4e-187 wgaE S Polysaccharide pyruvyl transferase
KEFIEGDI_03732 6.1e-285 ahpF O Alkyl hydroperoxide reductase
KEFIEGDI_03733 3.6e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
KEFIEGDI_03734 5.5e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KEFIEGDI_03735 2.9e-230 gntP EG COG2610 H gluconate symporter and related permeases
KEFIEGDI_03736 1.9e-302 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
KEFIEGDI_03737 7.3e-127 gntR K transcriptional
KEFIEGDI_03738 4.7e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KEFIEGDI_03739 5.6e-189 yxaB GM Polysaccharide pyruvyl transferase
KEFIEGDI_03740 3.2e-116 yxaC M effector of murein hydrolase
KEFIEGDI_03741 1.1e-44 S LrgA family
KEFIEGDI_03742 9.8e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
KEFIEGDI_03743 4.3e-59 ywdK S small membrane protein
KEFIEGDI_03744 1e-235 ywdJ F Xanthine uracil
KEFIEGDI_03745 1.9e-47 ywdI S Family of unknown function (DUF5327)
KEFIEGDI_03746 3.1e-256 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
KEFIEGDI_03747 4.2e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KEFIEGDI_03748 2.1e-151 ywdF GT2,GT4 S Glycosyltransferase like family 2
KEFIEGDI_03750 7.5e-112 ywdD
KEFIEGDI_03751 1.3e-57 pex K Transcriptional regulator PadR-like family
KEFIEGDI_03752 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KEFIEGDI_03753 2e-28 ywdA
KEFIEGDI_03754 8.6e-289 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
KEFIEGDI_03755 6.6e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KEFIEGDI_03756 2e-27 focA P Formate/nitrite transporter
KEFIEGDI_03757 1.7e-78 focA P Formate/nitrite transporter
KEFIEGDI_03758 1.6e-149 sacT K transcriptional antiterminator
KEFIEGDI_03761 0.0 vpr O Belongs to the peptidase S8 family
KEFIEGDI_03762 3.6e-185 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KEFIEGDI_03763 2.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
KEFIEGDI_03764 3.8e-202 rodA D Belongs to the SEDS family
KEFIEGDI_03765 1.3e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
KEFIEGDI_03766 1e-154 ydfC EG EamA-like transporter family
KEFIEGDI_03767 2.1e-271 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KEFIEGDI_03768 6.1e-114 ydfE S Flavin reductase like domain
KEFIEGDI_03769 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
KEFIEGDI_03770 2.3e-23 ydfH 2.7.13.3 T Histidine kinase
KEFIEGDI_03771 3e-108 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KEFIEGDI_03772 4.6e-245 ydfJ S drug exporters of the RND superfamily
KEFIEGDI_03773 1.7e-34 ydfJ S drug exporters of the RND superfamily
KEFIEGDI_03774 2.8e-64 ydfJ S drug exporters of the RND superfamily
KEFIEGDI_03775 1.9e-116 S Protein of unknown function (DUF554)
KEFIEGDI_03776 2.7e-146 K Bacterial transcription activator, effector binding domain
KEFIEGDI_03777 8.6e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KEFIEGDI_03778 2.4e-110 ydfN C nitroreductase
KEFIEGDI_03779 2.6e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
KEFIEGDI_03780 1.5e-62 mhqP S DoxX
KEFIEGDI_03781 1e-54 traF CO Thioredoxin
KEFIEGDI_03782 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
KEFIEGDI_03785 4.5e-53 ydfR S Protein of unknown function (DUF421)
KEFIEGDI_03786 1e-28 ydfR S Protein of unknown function (DUF421)
KEFIEGDI_03787 3.1e-24 ydfS S Protein of unknown function (DUF421)
KEFIEGDI_03788 1.3e-70 ydfS S Protein of unknown function (DUF421)
KEFIEGDI_03789 1.9e-74 cotP O Belongs to the small heat shock protein (HSP20) family
KEFIEGDI_03790 2.3e-37 ydgA S Spore germination protein gerPA/gerPF
KEFIEGDI_03791 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
KEFIEGDI_03792 8.7e-94 K Bacterial regulatory proteins, tetR family
KEFIEGDI_03793 8.1e-52 S DoxX-like family
KEFIEGDI_03794 1.3e-84 yycN 2.3.1.128 K Acetyltransferase
KEFIEGDI_03795 2.3e-48 FG HIT domain
KEFIEGDI_03797 1.1e-137 EGP Major facilitator Superfamily
KEFIEGDI_03798 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KEFIEGDI_03799 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KEFIEGDI_03800 1.8e-37 yaaB S Domain of unknown function (DUF370)
KEFIEGDI_03801 2.7e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KEFIEGDI_03802 2.4e-33 yaaA S S4 domain
KEFIEGDI_03803 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KEFIEGDI_03804 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KEFIEGDI_03805 1.2e-53 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KEFIEGDI_03806 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KEFIEGDI_03807 3.2e-107 jag S single-stranded nucleic acid binding R3H
KEFIEGDI_03808 3.7e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KEFIEGDI_03809 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KEFIEGDI_03810 7.7e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
KEFIEGDI_03811 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
KEFIEGDI_03812 3.4e-71 S Bacterial PH domain
KEFIEGDI_03813 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
KEFIEGDI_03814 2.1e-149 spo0J K Belongs to the ParB family
KEFIEGDI_03815 1.8e-45
KEFIEGDI_03816 4e-216 S nuclease activity
KEFIEGDI_03817 4e-38 yxiC S Family of unknown function (DUF5344)
KEFIEGDI_03818 6.7e-20 S Domain of unknown function (DUF5082)
KEFIEGDI_03819 9.7e-266 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
KEFIEGDI_03820 8.6e-249 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KEFIEGDI_03821 2.6e-13 lysP E amino acid
KEFIEGDI_03822 2.7e-115 lysP E amino acid
KEFIEGDI_03823 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
KEFIEGDI_03824 2.2e-205 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KEFIEGDI_03825 5.9e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KEFIEGDI_03826 1.8e-173 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KEFIEGDI_03827 3.2e-147 yxxB S Domain of Unknown Function (DUF1206)
KEFIEGDI_03828 4.8e-109 eutH E Ethanolamine utilisation protein, EutH
KEFIEGDI_03829 8.3e-62 eutH E Ethanolamine utilisation protein, EutH
KEFIEGDI_03830 2.4e-66 yxeQ S MmgE/PrpD family
KEFIEGDI_03831 1.3e-37 yxeQ S MmgE/PrpD family
KEFIEGDI_03832 1.2e-75 umuC 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KEFIEGDI_03833 2.9e-75 L HNH nucleases
KEFIEGDI_03834 2.7e-57 L HNH nucleases
KEFIEGDI_03835 4e-07 L COG3344 Retron-type reverse transcriptase
KEFIEGDI_03836 3e-34
KEFIEGDI_03837 7.3e-25 smtA 2.1.1.104 S O-methyltransferase
KEFIEGDI_03838 1.3e-88 batE T Bacterial SH3 domain homologues
KEFIEGDI_03839 9.6e-50 yfhL S SdpI/YhfL protein family
KEFIEGDI_03840 1.3e-170 yfhM S Alpha beta hydrolase
KEFIEGDI_03841 3.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KEFIEGDI_03842 0.0 yfhO S Bacterial membrane protein YfhO
KEFIEGDI_03843 2.1e-185 yfhP S membrane-bound metal-dependent
KEFIEGDI_03844 2.5e-210 mutY L A G-specific
KEFIEGDI_03845 1.2e-35 yfhS
KEFIEGDI_03846 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEFIEGDI_03847 5.3e-08 sspE S Small, acid-soluble spore protein, gamma-type
KEFIEGDI_03848 4.9e-48 ygaB S YgaB-like protein
KEFIEGDI_03849 1.3e-104 ygaC J Belongs to the UPF0374 family
KEFIEGDI_03850 1.8e-301 ygaD V ABC transporter
KEFIEGDI_03851 2.8e-178 ygaE S Membrane
KEFIEGDI_03852 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KEFIEGDI_03853 1.1e-86 bcp 1.11.1.15 O Peroxiredoxin
KEFIEGDI_03854 4e-80 perR P Belongs to the Fur family
KEFIEGDI_03855 3.6e-55 ygzB S UPF0295 protein
KEFIEGDI_03856 4.3e-166 ygxA S Nucleotidyltransferase-like
KEFIEGDI_03857 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KEFIEGDI_03858 1.1e-209 ftsW D Belongs to the SEDS family
KEFIEGDI_03859 8.7e-44 ylaN S Belongs to the UPF0358 family
KEFIEGDI_03860 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
KEFIEGDI_03861 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KEFIEGDI_03862 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
KEFIEGDI_03863 4.4e-88 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KEFIEGDI_03864 2.5e-32 ylaI S protein conserved in bacteria
KEFIEGDI_03865 4.2e-47 ylaH S YlaH-like protein
KEFIEGDI_03866 0.0 typA T GTP-binding protein TypA
KEFIEGDI_03867 3.1e-21 S Family of unknown function (DUF5325)
KEFIEGDI_03868 7.7e-37 ylaE
KEFIEGDI_03869 9.1e-12 sigC S Putative zinc-finger
KEFIEGDI_03870 5.6e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
KEFIEGDI_03871 2.7e-42 ylaB
KEFIEGDI_03872 0.0 ylaA
KEFIEGDI_03873 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
KEFIEGDI_03874 1.6e-136 yabG S peptidase
KEFIEGDI_03875 6.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KEFIEGDI_03876 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KEFIEGDI_03877 7.6e-167 rpfB GH23 T protein conserved in bacteria
KEFIEGDI_03878 2.2e-142 tatD L hydrolase, TatD
KEFIEGDI_03879 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KEFIEGDI_03880 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
KEFIEGDI_03881 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KEFIEGDI_03882 1.5e-49 yazA L endonuclease containing a URI domain
KEFIEGDI_03883 2.7e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
KEFIEGDI_03884 4.8e-31 yabA L Involved in initiation control of chromosome replication
KEFIEGDI_03885 2.3e-145 yaaT S stage 0 sporulation protein
KEFIEGDI_03886 1.1e-181 holB 2.7.7.7 L DNA polymerase III
KEFIEGDI_03887 1.5e-71 yaaR S protein conserved in bacteria
KEFIEGDI_03888 2.2e-54 yaaQ S protein conserved in bacteria
KEFIEGDI_03889 1.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KEFIEGDI_03890 4e-270 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
KEFIEGDI_03891 2.2e-202 yaaN P Belongs to the TelA family
KEFIEGDI_03892 2e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
KEFIEGDI_03893 3.4e-31 csfB S Inhibitor of sigma-G Gin
KEFIEGDI_03894 0.0 prkA T Ser protein kinase
KEFIEGDI_03895 5.5e-225 yhbH S Belongs to the UPF0229 family
KEFIEGDI_03896 5.1e-60 yhbI K DNA-binding transcription factor activity
KEFIEGDI_03897 1.2e-96 yhbJ V COG1566 Multidrug resistance efflux pump
KEFIEGDI_03898 6.9e-271 yhcA EGP Major facilitator Superfamily
KEFIEGDI_03899 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
KEFIEGDI_03900 2.8e-37 yhcC
KEFIEGDI_03901 1.9e-53
KEFIEGDI_03902 1.9e-59 yhcF K Transcriptional regulator
KEFIEGDI_03903 8.8e-122 yhcG V ABC transporter, ATP-binding protein
KEFIEGDI_03904 5.5e-164 yhcH V ABC transporter, ATP-binding protein
KEFIEGDI_03905 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KEFIEGDI_03906 1e-30 cspB K Cold-shock protein
KEFIEGDI_03907 2.4e-150 metQ M Belongs to the nlpA lipoprotein family
KEFIEGDI_03908 1.6e-43 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
KEFIEGDI_03909 2.5e-48 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
KEFIEGDI_03910 1.8e-219 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KEFIEGDI_03911 6.4e-41 yhcM
KEFIEGDI_03912 2.1e-61 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KEFIEGDI_03914 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
KEFIEGDI_03915 7.9e-32 yaaL S Protein of unknown function (DUF2508)
KEFIEGDI_03916 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KEFIEGDI_03917 1.2e-36 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KEFIEGDI_03918 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KEFIEGDI_03919 2.5e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KEFIEGDI_03920 2.4e-75 yaaI Q COG1335 Amidases related to nicotinamidase
KEFIEGDI_03921 2.3e-208 yaaH M Glycoside Hydrolase Family
KEFIEGDI_03922 1e-113 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
KEFIEGDI_03923 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
KEFIEGDI_03924 1.3e-09
KEFIEGDI_03925 3.6e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KEFIEGDI_03926 1e-107 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KEFIEGDI_03927 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KEFIEGDI_03928 1.2e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KEFIEGDI_03929 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KEFIEGDI_03930 3.9e-181 yaaC S YaaC-like Protein
KEFIEGDI_03932 3.5e-166 bla 3.5.2.6 V beta-lactamase
KEFIEGDI_03933 1.4e-113 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
KEFIEGDI_03934 2e-76 yoaW
KEFIEGDI_03935 4.4e-30 yozG K Transcriptional regulator
KEFIEGDI_03936 1.2e-68 yoaS S Protein of unknown function (DUF2975)
KEFIEGDI_03937 1.5e-169 yoaR V vancomycin resistance protein
KEFIEGDI_03938 1e-79
KEFIEGDI_03941 8.3e-212 oxdC 4.1.1.2 G Oxalate decarboxylase
KEFIEGDI_03944 2.5e-129 yoqW S Belongs to the SOS response-associated peptidase family
KEFIEGDI_03945 8.9e-79 pelB 4.2.2.10, 4.2.2.2 G Amb_all
KEFIEGDI_03946 4.8e-40 pelB 4.2.2.10, 4.2.2.2 G Amb_all
KEFIEGDI_03947 3.1e-111 yoaK S Membrane
KEFIEGDI_03948 8.5e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
KEFIEGDI_03949 2.8e-279 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
KEFIEGDI_03950 1.7e-15 mcpU NT methyl-accepting chemotaxis protein
KEFIEGDI_03951 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KEFIEGDI_03953 1.9e-107 recN L Putative cell-wall binding lipoprotein
KEFIEGDI_03954 2.2e-191 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KEFIEGDI_03955 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KEFIEGDI_03956 2.4e-229 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KEFIEGDI_03957 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KEFIEGDI_03958 5.5e-62 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
KEFIEGDI_03959 2.9e-276 speA 4.1.1.19 E Arginine
KEFIEGDI_03960 1.6e-42 yktA S Belongs to the UPF0223 family
KEFIEGDI_03961 2.1e-117 yktB S Belongs to the UPF0637 family
KEFIEGDI_03962 7.1e-26 ykzI
KEFIEGDI_03963 7.4e-149 suhB 3.1.3.25 G Inositol monophosphatase
KEFIEGDI_03964 1.7e-76 ykzC S Acetyltransferase (GNAT) family
KEFIEGDI_03965 6.5e-165 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KEFIEGDI_03966 2.2e-145 ydfB J GNAT acetyltransferase
KEFIEGDI_03967 3.5e-73 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
KEFIEGDI_03968 1.4e-229 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KEFIEGDI_03969 5.3e-56 arsR K transcriptional
KEFIEGDI_03970 1.3e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KEFIEGDI_03971 3.1e-40 K HxlR-like helix-turn-helix
KEFIEGDI_03972 9.5e-53 ydeN S Serine hydrolase
KEFIEGDI_03973 3.5e-73 maoC I N-terminal half of MaoC dehydratase
KEFIEGDI_03974 1.2e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KEFIEGDI_03975 7.8e-152 ydeK EG -transporter
KEFIEGDI_03976 2e-84 K Transcriptional regulator C-terminal region
KEFIEGDI_03977 3.7e-15 ptsH G PTS HPr component phosphorylation site
KEFIEGDI_03978 3.2e-09 S SNARE associated Golgi protein
KEFIEGDI_03979 6.9e-108
KEFIEGDI_03980 3.8e-100 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
KEFIEGDI_03981 7.5e-104 L COG3436 Transposase and inactivated derivatives
KEFIEGDI_03982 1.7e-182 E Hydrolase CocE NonD family
KEFIEGDI_03983 1.5e-126 S X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain
KEFIEGDI_03985 2.2e-14 K dihydroxyacetone kinase regulator
KEFIEGDI_03986 7.2e-21 K dihydroxyacetone kinase regulator
KEFIEGDI_03987 6.5e-19 K transcriptional regulator
KEFIEGDI_03989 6.7e-113 yhzB S B3/4 domain
KEFIEGDI_03990 1.1e-222 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KEFIEGDI_03991 2.8e-176 yhbB S Putative amidase domain
KEFIEGDI_03992 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KEFIEGDI_03993 5.1e-103 yhbD K Protein of unknown function (DUF4004)
KEFIEGDI_03994 2.7e-57 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
KEFIEGDI_03995 1.4e-63 yodA S tautomerase
KEFIEGDI_03996 1.1e-205 gntP EG COG2610 H gluconate symporter and related permeases
KEFIEGDI_03997 1.6e-09
KEFIEGDI_03998 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
KEFIEGDI_03999 6.6e-162 rarD S -transporter
KEFIEGDI_04000 4.3e-43
KEFIEGDI_04001 2.2e-60 yojF S Protein of unknown function (DUF1806)
KEFIEGDI_04002 2.1e-125 yojG S deacetylase
KEFIEGDI_04003 1.2e-149 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KEFIEGDI_04004 1.3e-241 norM V Multidrug efflux pump
KEFIEGDI_04006 2.9e-108 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KEFIEGDI_04007 2.5e-228 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
KEFIEGDI_04008 2.1e-195 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KEFIEGDI_04009 1.6e-115 yknW S Yip1 domain
KEFIEGDI_04010 1.2e-157 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KEFIEGDI_04011 9.4e-124 macB V ABC transporter, ATP-binding protein
KEFIEGDI_04012 7.3e-209 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
KEFIEGDI_04013 4e-136 fruR K Transcriptional regulator
KEFIEGDI_04014 1.5e-166 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
KEFIEGDI_04015 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
KEFIEGDI_04016 2.4e-104 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KEFIEGDI_04017 1.1e-38 ykoA
KEFIEGDI_04018 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KEFIEGDI_04019 6.9e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KEFIEGDI_04020 2.7e-45 ydeH
KEFIEGDI_04021 3.6e-44 ydeG EGP Major facilitator superfamily
KEFIEGDI_04022 7.1e-125 ydeG EGP Major facilitator superfamily
KEFIEGDI_04023 1e-76 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KEFIEGDI_04024 2.6e-163 ydeE K AraC family transcriptional regulator
KEFIEGDI_04025 4.5e-169 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KEFIEGDI_04026 1.2e-163 rhaS5 K AraC-like ligand binding domain
KEFIEGDI_04027 3.4e-77 carD K Transcription factor
KEFIEGDI_04028 8.7e-30 cspL K Cold shock
KEFIEGDI_04029 9.6e-40
KEFIEGDI_04030 3.4e-33 K Helix-turn-helix XRE-family like proteins
KEFIEGDI_04031 3e-145 ykrA S hydrolases of the HAD superfamily
KEFIEGDI_04032 8.2e-31 ykzG S Belongs to the UPF0356 family
KEFIEGDI_04033 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KEFIEGDI_04034 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KEFIEGDI_04035 1.2e-115 ktrA P COG0569 K transport systems, NAD-binding component
KEFIEGDI_04036 4.1e-144 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
KEFIEGDI_04037 3.3e-239 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
KEFIEGDI_04038 1.5e-43 abrB K of stationary sporulation gene expression
KEFIEGDI_04039 7.7e-183 mreB D Rod-share determining protein MreBH
KEFIEGDI_04040 1.1e-12 S Uncharacterized protein YkpC
KEFIEGDI_04041 1e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
KEFIEGDI_04042 3.4e-15 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
KEFIEGDI_04043 2e-41 smtA 2.1.1.104 S O-methyltransferase
KEFIEGDI_04044 5.9e-191 benK EGP Major facilitator Superfamily
KEFIEGDI_04045 2.8e-166 MA20_26520 1.13.11.2 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KEFIEGDI_04046 2.9e-63 K FCD
KEFIEGDI_04047 1.5e-59 MA20_21375 3.5.99.10 J Endoribonuclease L-PSP
KEFIEGDI_04048 2e-116 4.2.1.83 S GlcNAc-PI de-N-acetylase
KEFIEGDI_04049 1.2e-94 ligK 4.1.3.17 H Aldolase/RraA
KEFIEGDI_04050 1.4e-156 EGP Major facilitator Superfamily
KEFIEGDI_04051 4.5e-227 I acetylesterase activity
KEFIEGDI_04053 1.7e-112 L DDE domain
KEFIEGDI_04054 3.8e-24 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KEFIEGDI_04055 3.3e-42 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
KEFIEGDI_04056 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KEFIEGDI_04057 2.1e-39 ptsH G phosphocarrier protein HPr
KEFIEGDI_04058 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KEFIEGDI_04059 1.1e-126 glcT K antiterminator
KEFIEGDI_04061 6.4e-179 ykvZ 5.1.1.1 K Transcriptional regulator
KEFIEGDI_04062 4.1e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KEFIEGDI_04063 2.3e-09
KEFIEGDI_04064 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
KEFIEGDI_04065 6.7e-121 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KEFIEGDI_04066 1.8e-31 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KEFIEGDI_04070 1.9e-10 K Cro/C1-type HTH DNA-binding domain
KEFIEGDI_04071 1.3e-92 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KEFIEGDI_04073 1.3e-242 cisA2 L Recombinase
KEFIEGDI_04074 6.2e-69 S SMI1 / KNR4 family
KEFIEGDI_04075 4.5e-54 S DNase/tRNase domain of colicin-like bacteriocin
KEFIEGDI_04076 5.8e-30 S Bacterial PH domain
KEFIEGDI_04077 7.3e-105 yokF 3.1.31.1 L RNA catabolic process
KEFIEGDI_04078 7.9e-36
KEFIEGDI_04079 1.6e-77 yokH G SMI1 / KNR4 family
KEFIEGDI_04080 0.0 M nucleic acid phosphodiester bond hydrolysis
KEFIEGDI_04081 2.3e-22
KEFIEGDI_04082 6.3e-49 S YolD-like protein
KEFIEGDI_04083 3.6e-44 K Protein of unknown function (DUF4065)
KEFIEGDI_04086 1.2e-12
KEFIEGDI_04087 5.3e-19
KEFIEGDI_04088 1.8e-246 M nucleic acid phosphodiester bond hydrolysis
KEFIEGDI_04089 3e-31
KEFIEGDI_04090 6.9e-23
KEFIEGDI_04091 1.5e-30
KEFIEGDI_04092 1.3e-44 yfhJ S WVELL protein
KEFIEGDI_04093 6.2e-20 sspK S reproduction
KEFIEGDI_04094 1.1e-209 yfhI EGP Major facilitator Superfamily
KEFIEGDI_04095 9.7e-52 yfhH S Protein of unknown function (DUF1811)
KEFIEGDI_04096 7.4e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
KEFIEGDI_04097 1.3e-38 yfhF S nucleoside-diphosphate sugar epimerase
KEFIEGDI_04098 3.2e-101 yfhF S nucleoside-diphosphate sugar epimerase
KEFIEGDI_04100 2.1e-25 yfhD S YfhD-like protein
KEFIEGDI_04101 9.7e-106 yfhC C nitroreductase
KEFIEGDI_04102 6.9e-164 yfhB 5.3.3.17 S PhzF family
KEFIEGDI_04103 9.9e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEFIEGDI_04104 1.3e-42 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEFIEGDI_04105 1.9e-119 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEFIEGDI_04106 1.1e-173 yfiY P ABC transporter substrate-binding protein
KEFIEGDI_04107 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
KEFIEGDI_04108 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
KEFIEGDI_04109 1.8e-31 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KEFIEGDI_04110 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
KEFIEGDI_04111 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
KEFIEGDI_04112 2.6e-244 moeA 2.10.1.1 H molybdopterin
KEFIEGDI_04113 5.9e-191 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KEFIEGDI_04114 1.6e-108 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KEFIEGDI_04115 1.8e-144 yknT
KEFIEGDI_04116 7.9e-88 L Tn3 transposase DDE domain
KEFIEGDI_04117 1.7e-76
KEFIEGDI_04118 8.9e-98 EG Spore germination protein
KEFIEGDI_04119 1.5e-66 S TIGRFAM germination protein, Ger(x)C family
KEFIEGDI_04120 1.5e-24 S Protein of unknown function (DUF2642)
KEFIEGDI_04121 9.4e-161 cat P Catalase
KEFIEGDI_04122 6e-26 S Protein of unknown function (DUF1657)
KEFIEGDI_04123 4.1e-78 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KEFIEGDI_04124 2.6e-80 spoVAC S stage V sporulation protein AC
KEFIEGDI_04125 1e-195 spoVAD I Stage V sporulation protein AD
KEFIEGDI_04126 8.5e-57 spoVAE S stage V sporulation protein
KEFIEGDI_04127 5.8e-29 S Protein of unknown function (DUF1657)
KEFIEGDI_04128 1.9e-150 yetF1 S membrane
KEFIEGDI_04129 1.2e-70 S Protein of unknown function (DUF421)
KEFIEGDI_04130 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KEFIEGDI_04131 4.9e-79 yfiV K transcriptional
KEFIEGDI_04132 2.1e-280 yfiU EGP Major facilitator Superfamily
KEFIEGDI_04133 6.8e-98 yfiT S Belongs to the metal hydrolase YfiT family
KEFIEGDI_04134 7e-194 yfiS EGP Major facilitator Superfamily
KEFIEGDI_04135 1.7e-108 yfiR K Transcriptional regulator
KEFIEGDI_04136 3.9e-193 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KEFIEGDI_04137 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KEFIEGDI_04138 2.1e-144 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
KEFIEGDI_04139 1.1e-170 ssuA M Sulfonate ABC transporter
KEFIEGDI_04140 1.2e-146 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KEFIEGDI_04141 7.6e-216 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
KEFIEGDI_04143 3.9e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KEFIEGDI_04144 3.8e-76 ygaO
KEFIEGDI_04145 4.4e-29 K Transcriptional regulator
KEFIEGDI_04146 2.4e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
KEFIEGDI_04147 8.5e-136 yobQ K helix_turn_helix, arabinose operon control protein
KEFIEGDI_04148 2.1e-137 yobR 2.3.1.1 J FR47-like protein
KEFIEGDI_04149 3.3e-98 yobS K Transcriptional regulator
KEFIEGDI_04150 1.1e-87 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
KEFIEGDI_04151 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
KEFIEGDI_04152 8.7e-173 yobV K WYL domain
KEFIEGDI_04153 6.3e-91 yobW
KEFIEGDI_04154 1e-51 czrA K transcriptional
KEFIEGDI_04155 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KEFIEGDI_04156 4.8e-218 yxjG 2.1.1.14 E Methionine synthase
KEFIEGDI_04157 5.3e-217 yxjG 2.1.1.14 E Methionine synthase
KEFIEGDI_04158 2.8e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
KEFIEGDI_04159 8.8e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KEFIEGDI_04160 1.8e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KEFIEGDI_04161 2.4e-251 yxjC EG COG2610 H gluconate symporter and related permeases
KEFIEGDI_04162 7.4e-155 rlmA 2.1.1.187 Q Methyltransferase domain
KEFIEGDI_04167 7.8e-08
KEFIEGDI_04175 2e-08
KEFIEGDI_04179 2.5e-141 spo0M S COG4326 Sporulation control protein
KEFIEGDI_04180 4.4e-26
KEFIEGDI_04181 4.3e-129 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
KEFIEGDI_04182 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KEFIEGDI_04185 1e-306 rocB E arginine degradation protein
KEFIEGDI_04186 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
KEFIEGDI_04187 6.2e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KEFIEGDI_04188 1.1e-18 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KEFIEGDI_04189 1.5e-172 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KEFIEGDI_04190 2e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KEFIEGDI_04191 3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KEFIEGDI_04192 1.7e-76 S Protein of unknown function (DUF1453)
KEFIEGDI_04193 2.3e-189 yxjM T Signal transduction histidine kinase
KEFIEGDI_04194 1.9e-113 K helix_turn_helix, Lux Regulon
KEFIEGDI_04195 1e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KEFIEGDI_04198 7.1e-86 yxjI S LURP-one-related
KEFIEGDI_04199 2.5e-115 ywaC 2.7.6.5 S protein conserved in bacteria
KEFIEGDI_04200 9.8e-250 ywaD 3.4.11.10, 3.4.11.6 S PA domain
KEFIEGDI_04201 3.9e-229 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KEFIEGDI_04202 2e-86 ywaE K Transcriptional regulator
KEFIEGDI_04203 5.3e-122 ywaF S Integral membrane protein
KEFIEGDI_04204 7e-169 gspA M General stress
KEFIEGDI_04206 1.5e-84 V AAA domain, putative AbiEii toxin, Type IV TA system
KEFIEGDI_04207 1.9e-79 hpr K helix_turn_helix multiple antibiotic resistance protein
KEFIEGDI_04208 6.8e-234 yoaB EGP Major facilitator Superfamily
KEFIEGDI_04209 4.2e-89 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
KEFIEGDI_04210 5.4e-286 clsA_1 I PLD-like domain
KEFIEGDI_04211 2.8e-89 thiT S Thiamine transporter protein (Thia_YuaJ)
KEFIEGDI_04212 3.4e-94 M1-753 M FR47-like protein
KEFIEGDI_04213 2e-187 yuaG 3.4.21.72 S protein conserved in bacteria
KEFIEGDI_04214 1.9e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
KEFIEGDI_04215 5.3e-09 yuaE S DinB superfamily
KEFIEGDI_04216 3e-57 yuaE S DinB superfamily
KEFIEGDI_04217 3.1e-44 yhdK S Sigma-M inhibitor protein
KEFIEGDI_04218 1.5e-200 yhdL S Sigma factor regulator N-terminal
KEFIEGDI_04219 4e-76 sigM K Belongs to the sigma-70 factor family. ECF subfamily
KEFIEGDI_04220 2.2e-190 yhdN C Aldo keto reductase
KEFIEGDI_04221 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KEFIEGDI_04222 1.5e-117 aacC 2.3.1.81 V aminoglycoside
KEFIEGDI_04223 6.2e-58 ybbA S Putative esterase
KEFIEGDI_04224 1.1e-112 L Integrase core domain
KEFIEGDI_04225 1.1e-40 L transposase activity
KEFIEGDI_04226 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
KEFIEGDI_04227 1.1e-08
KEFIEGDI_04230 2.2e-173 S response regulator aspartate phosphatase
KEFIEGDI_04231 2.6e-35 yjcS S Antibiotic biosynthesis monooxygenase
KEFIEGDI_04232 7.7e-49 L Transposase
KEFIEGDI_04235 5.8e-15 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
KEFIEGDI_04236 3.3e-21 yokK S SMI1-KNR4 cell-wall
KEFIEGDI_04237 8e-93 yokJ S SMI1 / KNR4 family (SUKH-1)
KEFIEGDI_04238 1.1e-86 UW nuclease activity
KEFIEGDI_04239 2e-43 yjqB S Pfam:DUF867
KEFIEGDI_04240 3.3e-59 yjqB S Pfam:DUF867
KEFIEGDI_04241 1.8e-60 yjqA S Bacterial PH domain
KEFIEGDI_04242 3e-165 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
KEFIEGDI_04243 7e-40 S YCII-related domain
KEFIEGDI_04244 3e-249 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
KEFIEGDI_04246 4e-78 yjoA S DinB family
KEFIEGDI_04247 9.3e-54 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
KEFIEGDI_04248 3.6e-133 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
KEFIEGDI_04249 1.8e-104 yrkC G Cupin domain
KEFIEGDI_04251 7.2e-19 S Tetratricopeptide repeat
KEFIEGDI_04252 8.9e-12 cwlJ 3.5.1.28 M Cell wall
KEFIEGDI_04253 3.2e-77 O Hsp20/alpha crystallin family
KEFIEGDI_04254 9.6e-36 L COG3385 FOG Transposase and inactivated derivatives
KEFIEGDI_04255 5.8e-09 S Spore germination B3/ GerAC like, C-terminal
KEFIEGDI_04256 9.7e-211 S response regulator aspartate phosphatase
KEFIEGDI_04258 1.8e-220 L Transposase
KEFIEGDI_04260 1.8e-136 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
KEFIEGDI_04261 3.4e-39 S COG NOG14552 non supervised orthologous group
KEFIEGDI_04266 2e-08
KEFIEGDI_04271 1.1e-35 L Transposase
KEFIEGDI_04272 1.2e-138 L HTH-like domain
KEFIEGDI_04273 1.1e-35 tnpIS3 L Transposase
KEFIEGDI_04274 1.3e-42 L Integrase core domain
KEFIEGDI_04278 2e-08
KEFIEGDI_04281 6e-118 L COG3666 Transposase and inactivated derivatives
KEFIEGDI_04282 9.1e-50 L Transposase
KEFIEGDI_04283 7.6e-143 L COG3385 FOG Transposase and inactivated derivatives
KEFIEGDI_04284 4.1e-90 L COG3666 Transposase and inactivated derivatives
KEFIEGDI_04285 6.7e-73 yokH G SMI1 / KNR4 family
KEFIEGDI_04286 7.2e-26
KEFIEGDI_04287 2.6e-22 S Domain of unknown function (DUF334)
KEFIEGDI_04288 1.1e-54 S Bacterial mobilisation protein (MobC)
KEFIEGDI_04291 1.7e-41 tcyA ET ABC transporter
KEFIEGDI_04292 5.9e-57 speD 2.5.1.16, 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KEFIEGDI_04293 2.2e-27 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KEFIEGDI_04294 6.1e-22 T Sensors of blue-light using FAD
KEFIEGDI_04295 8.6e-34 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KEFIEGDI_04296 4.3e-32 K helix_turn_helix, Arsenical Resistance Operon Repressor
KEFIEGDI_04297 3e-36 L transposase activity

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)