ORF_ID e_value Gene_name EC_number CAZy COGs Description
MFNHADDB_00001 2.2e-93 M Glycosyltransferase like family
MFNHADDB_00002 2.2e-120 H Methionine biosynthesis protein MetW
MFNHADDB_00003 3.9e-196 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MFNHADDB_00004 1.7e-214 sumf2 2.1.1.295 GT2,GT4 H N-terminal domain of galactosyltransferase
MFNHADDB_00006 6.8e-98 ynaD J Acetyltransferase (GNAT) domain
MFNHADDB_00008 3.6e-75 S CAAX protease self-immunity
MFNHADDB_00009 4.7e-08 S Uncharacterised protein family (UPF0715)
MFNHADDB_00010 1.5e-22 K Cro/C1-type HTH DNA-binding domain
MFNHADDB_00011 5.8e-112 ynaE S Domain of unknown function (DUF3885)
MFNHADDB_00014 5.3e-78 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
MFNHADDB_00015 6.2e-75 yhbS S family acetyltransferase
MFNHADDB_00016 2.3e-254 xynT G MFS/sugar transport protein
MFNHADDB_00017 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
MFNHADDB_00018 2.1e-213 xylR GK ROK family
MFNHADDB_00019 1.3e-262 xylA 5.3.1.5 G Belongs to the xylose isomerase family
MFNHADDB_00020 8.7e-292 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
MFNHADDB_00021 6.4e-111 yokF 3.1.31.1 L RNA catabolic process
MFNHADDB_00022 2.3e-254 iolT EGP Major facilitator Superfamily
MFNHADDB_00023 8.5e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MFNHADDB_00024 1e-81 yncE S Protein of unknown function (DUF2691)
MFNHADDB_00025 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
MFNHADDB_00026 5.2e-15
MFNHADDB_00029 8.6e-164 S Thymidylate synthase
MFNHADDB_00030 1.7e-131 S Domain of unknown function, YrpD
MFNHADDB_00033 7.9e-25 tatA U protein secretion
MFNHADDB_00034 1.8e-71
MFNHADDB_00035 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
MFNHADDB_00038 5.6e-35 gerAA EG Spore germination protein
MFNHADDB_00039 1.3e-123 gerAB U Spore germination
MFNHADDB_00040 1.1e-59 gerAB U Spore germination
MFNHADDB_00041 3.6e-219 gerLC S Spore germination protein
MFNHADDB_00042 2.5e-152 yndG S DoxX-like family
MFNHADDB_00043 5.4e-115 yndH S Domain of unknown function (DUF4166)
MFNHADDB_00044 2.7e-310 yndJ S YndJ-like protein
MFNHADDB_00046 4.7e-137 yndL S Replication protein
MFNHADDB_00047 5.8e-74 yndM S Protein of unknown function (DUF2512)
MFNHADDB_00048 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MFNHADDB_00049 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MFNHADDB_00050 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MFNHADDB_00051 4.5e-112 yneB L resolvase
MFNHADDB_00052 1.3e-32 ynzC S UPF0291 protein
MFNHADDB_00053 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MFNHADDB_00054 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
MFNHADDB_00055 1.8e-28 yneF S UPF0154 protein
MFNHADDB_00056 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
MFNHADDB_00057 7.1e-127 ccdA O cytochrome c biogenesis protein
MFNHADDB_00058 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
MFNHADDB_00059 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
MFNHADDB_00060 4.2e-74 yneK S Protein of unknown function (DUF2621)
MFNHADDB_00061 2.2e-63 hspX O Spore coat protein
MFNHADDB_00062 3.9e-19 sspP S Belongs to the SspP family
MFNHADDB_00063 2.2e-14 sspO S Belongs to the SspO family
MFNHADDB_00064 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MFNHADDB_00065 5.9e-91 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MFNHADDB_00067 3.1e-08 sspN S Small acid-soluble spore protein N family
MFNHADDB_00068 3.9e-35 tlp S Belongs to the Tlp family
MFNHADDB_00069 2.2e-72 yneP S Thioesterase-like superfamily
MFNHADDB_00070 1.9e-52 yneQ
MFNHADDB_00071 4.1e-49 yneR S Belongs to the HesB IscA family
MFNHADDB_00072 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MFNHADDB_00073 6.6e-69 yccU S CoA-binding protein
MFNHADDB_00074 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MFNHADDB_00075 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MFNHADDB_00076 2.3e-12
MFNHADDB_00077 1.3e-57 ynfC
MFNHADDB_00078 9e-251 agcS E Sodium alanine symporter
MFNHADDB_00079 2.4e-294 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
MFNHADDB_00081 1.8e-250 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
MFNHADDB_00082 1.3e-295 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
MFNHADDB_00083 2.2e-78 yngA S membrane
MFNHADDB_00084 1.3e-162 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MFNHADDB_00085 5.5e-104 yngC S membrane-associated protein
MFNHADDB_00086 1.2e-232 nrnB S phosphohydrolase (DHH superfamily)
MFNHADDB_00087 2.5e-286 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MFNHADDB_00088 4.1e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MFNHADDB_00089 4.4e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
MFNHADDB_00090 7.3e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
MFNHADDB_00091 3.3e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
MFNHADDB_00092 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MFNHADDB_00093 5.4e-209 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
MFNHADDB_00094 7.7e-304 yngK T Glycosyl hydrolase-like 10
MFNHADDB_00095 1.1e-63 yngL S Protein of unknown function (DUF1360)
MFNHADDB_00096 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
MFNHADDB_00097 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFNHADDB_00098 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFNHADDB_00099 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFNHADDB_00100 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFNHADDB_00101 4.4e-272 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
MFNHADDB_00102 1.8e-189 yoxA 5.1.3.3 G Aldose 1-epimerase
MFNHADDB_00103 5.6e-245 yoeA V MATE efflux family protein
MFNHADDB_00104 3.1e-98 yoeB S IseA DL-endopeptidase inhibitor
MFNHADDB_00106 2.2e-96 L Integrase
MFNHADDB_00107 5.1e-34 yoeD G Helix-turn-helix domain
MFNHADDB_00108 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MFNHADDB_00109 3e-156 gltR1 K Transcriptional regulator
MFNHADDB_00110 1.9e-186 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MFNHADDB_00111 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MFNHADDB_00112 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
MFNHADDB_00113 7.8e-155 gltC K Transcriptional regulator
MFNHADDB_00114 7.8e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MFNHADDB_00115 7.3e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MFNHADDB_00116 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MFNHADDB_00117 2.4e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MFNHADDB_00118 2.8e-40 yoxC S Bacterial protein of unknown function (DUF948)
MFNHADDB_00119 1.6e-137 yoxB
MFNHADDB_00120 4.4e-89 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MFNHADDB_00121 2.2e-241 S Arylsulfotransferase (ASST)
MFNHADDB_00122 1.9e-126 3.1.1.3 I Lipase (class 3)
MFNHADDB_00123 4e-234 yoaB EGP Major facilitator Superfamily
MFNHADDB_00124 9.1e-278 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
MFNHADDB_00125 1.5e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFNHADDB_00126 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MFNHADDB_00127 1.1e-33 yoaF
MFNHADDB_00130 2.6e-13
MFNHADDB_00131 7.7e-35 S Protein of unknown function (DUF4025)
MFNHADDB_00132 1.1e-173 mcpU NT methyl-accepting chemotaxis protein
MFNHADDB_00133 2.5e-280 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
MFNHADDB_00134 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
MFNHADDB_00135 2.3e-111 yoaK S Membrane
MFNHADDB_00136 4.3e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
MFNHADDB_00137 3.2e-132 yoqW S Belongs to the SOS response-associated peptidase family
MFNHADDB_00140 1e-231 oxdC 4.1.1.2 G Oxalate decarboxylase
MFNHADDB_00142 3.4e-143 yoaP 3.1.3.18 K YoaP-like
MFNHADDB_00143 2.7e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
MFNHADDB_00145 1.5e-86
MFNHADDB_00146 7.1e-172 yoaR V vancomycin resistance protein
MFNHADDB_00147 7.3e-75 yoaS S Protein of unknown function (DUF2975)
MFNHADDB_00148 4.4e-30 yozG K Transcriptional regulator
MFNHADDB_00149 1.4e-147 yoaT S Protein of unknown function (DUF817)
MFNHADDB_00150 4.3e-158 yoaU K LysR substrate binding domain
MFNHADDB_00151 2.5e-158 yijE EG EamA-like transporter family
MFNHADDB_00152 2.7e-76 yoaW
MFNHADDB_00153 2.1e-114 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
MFNHADDB_00154 8.2e-168 bla 3.5.2.6 V beta-lactamase
MFNHADDB_00157 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
MFNHADDB_00158 6.9e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
MFNHADDB_00159 1.3e-35 S TM2 domain
MFNHADDB_00160 2.4e-56 K Helix-turn-helix
MFNHADDB_00163 9.5e-50 FG Scavenger mRNA decapping enzyme C-term binding
MFNHADDB_00169 5e-75 S Domain of unknown function (DUF4062)
MFNHADDB_00170 8e-73 S Domain of unknown function (DUF4062)
MFNHADDB_00171 4e-31 K Cro/C1-type HTH DNA-binding domain
MFNHADDB_00172 8.2e-36 comEA L photosystem II stabilization
MFNHADDB_00173 2.2e-120 isp O Subtilase family
MFNHADDB_00174 3.4e-89
MFNHADDB_00175 2.1e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
MFNHADDB_00176 5e-17
MFNHADDB_00178 1.7e-204 S aspartate phosphatase
MFNHADDB_00180 1.5e-158 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MFNHADDB_00181 4.2e-33 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MFNHADDB_00182 3.3e-44
MFNHADDB_00184 1.5e-19
MFNHADDB_00185 6.5e-10 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MFNHADDB_00186 5.1e-91 yokH G SMI1 / KNR4 family
MFNHADDB_00187 1.9e-275 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
MFNHADDB_00188 9.3e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
MFNHADDB_00189 7.9e-134 yobQ K helix_turn_helix, arabinose operon control protein
MFNHADDB_00190 9.1e-141 yobR 2.3.1.1 J FR47-like protein
MFNHADDB_00191 1.3e-97 yobS K Transcriptional regulator
MFNHADDB_00192 2.1e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
MFNHADDB_00193 5.4e-86 yobU K Bacterial transcription activator, effector binding domain
MFNHADDB_00194 9.3e-175 yobV K WYL domain
MFNHADDB_00195 7.4e-92 yobW
MFNHADDB_00196 1e-51 czrA K transcriptional
MFNHADDB_00197 5.8e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MFNHADDB_00198 1.5e-92 yozB S membrane
MFNHADDB_00199 6.4e-145
MFNHADDB_00200 1.6e-93 yocC
MFNHADDB_00201 9.3e-186 yocD 3.4.17.13 V peptidase S66
MFNHADDB_00202 5.3e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
MFNHADDB_00203 7.1e-198 desK 2.7.13.3 T Histidine kinase
MFNHADDB_00204 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MFNHADDB_00205 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
MFNHADDB_00206 0.0 recQ 3.6.4.12 L DNA helicase
MFNHADDB_00207 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MFNHADDB_00208 3.3e-83 dksA T general stress protein
MFNHADDB_00209 6.4e-54 yocL
MFNHADDB_00210 6.2e-32
MFNHADDB_00211 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
MFNHADDB_00212 1.1e-40 yozN
MFNHADDB_00213 2.5e-36 yocN
MFNHADDB_00214 4.2e-56 yozO S Bacterial PH domain
MFNHADDB_00215 2.7e-31 yozC
MFNHADDB_00216 1.5e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
MFNHADDB_00217 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
MFNHADDB_00218 3.9e-164 sodA 1.15.1.1 P Superoxide dismutase
MFNHADDB_00219 4.5e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MFNHADDB_00220 4.3e-167 yocS S -transporter
MFNHADDB_00221 9.4e-191 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MFNHADDB_00222 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MFNHADDB_00223 0.0 yojO P Von Willebrand factor
MFNHADDB_00224 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
MFNHADDB_00225 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MFNHADDB_00226 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MFNHADDB_00227 4.1e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
MFNHADDB_00228 2.9e-108 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MFNHADDB_00230 8e-244 norM V Multidrug efflux pump
MFNHADDB_00231 3.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MFNHADDB_00232 2.1e-125 yojG S deacetylase
MFNHADDB_00233 2.2e-60 yojF S Protein of unknown function (DUF1806)
MFNHADDB_00234 4.3e-43
MFNHADDB_00235 3.9e-162 rarD S -transporter
MFNHADDB_00236 5.7e-56 yozR S COG0071 Molecular chaperone (small heat shock protein)
MFNHADDB_00237 2.6e-09
MFNHADDB_00238 1.3e-206 gntP EG COG2610 H gluconate symporter and related permeases
MFNHADDB_00239 4.7e-64 yodA S tautomerase
MFNHADDB_00240 4.4e-55 yodB K transcriptional
MFNHADDB_00241 1.4e-107 yodC C nitroreductase
MFNHADDB_00242 1.2e-111 mhqD S Carboxylesterase
MFNHADDB_00243 3.2e-172 yodE E COG0346 Lactoylglutathione lyase and related lyases
MFNHADDB_00244 6.2e-28 S Protein of unknown function (DUF3311)
MFNHADDB_00245 1.1e-265 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MFNHADDB_00246 1.8e-251 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
MFNHADDB_00247 6.3e-128 yodH Q Methyltransferase
MFNHADDB_00248 5.2e-24 yodI
MFNHADDB_00249 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MFNHADDB_00250 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
MFNHADDB_00251 5.3e-09
MFNHADDB_00252 3.6e-54 yodL S YodL-like
MFNHADDB_00253 3.3e-104 yodM 3.6.1.27 I Acid phosphatase homologues
MFNHADDB_00254 2.8e-24 yozD S YozD-like protein
MFNHADDB_00256 1.6e-123 yodN
MFNHADDB_00257 1.4e-36 yozE S Belongs to the UPF0346 family
MFNHADDB_00258 8.3e-47 yokU S YokU-like protein, putative antitoxin
MFNHADDB_00259 5.1e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
MFNHADDB_00260 1.5e-152 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
MFNHADDB_00261 7.9e-257 yodQ 3.5.1.16 E Acetylornithine deacetylase
MFNHADDB_00262 2.8e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MFNHADDB_00263 7.1e-124 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MFNHADDB_00264 3.4e-247 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MFNHADDB_00266 4.1e-144 yiiD K acetyltransferase
MFNHADDB_00267 1.1e-255 cgeD M maturation of the outermost layer of the spore
MFNHADDB_00268 3.5e-38 cgeC
MFNHADDB_00269 1.5e-65 cgeA
MFNHADDB_00270 4.1e-186 cgeB S Spore maturation protein
MFNHADDB_00271 5.8e-211 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
MFNHADDB_00272 1.3e-124 4.2.1.115 GM Polysaccharide biosynthesis protein
MFNHADDB_00273 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MFNHADDB_00274 1.3e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MFNHADDB_00275 1.6e-70 ypoP K transcriptional
MFNHADDB_00276 7.6e-223 mepA V MATE efflux family protein
MFNHADDB_00277 5.5e-29 ypmT S Uncharacterized ympT
MFNHADDB_00278 5e-99 ypmS S protein conserved in bacteria
MFNHADDB_00279 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
MFNHADDB_00280 3.2e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MFNHADDB_00281 3.1e-40 ypmP S Protein of unknown function (DUF2535)
MFNHADDB_00282 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MFNHADDB_00283 1.6e-185 pspF K Transcriptional regulator
MFNHADDB_00284 4.2e-110 hlyIII S protein, Hemolysin III
MFNHADDB_00285 7.4e-112 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MFNHADDB_00286 7.9e-96 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MFNHADDB_00287 4.3e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MFNHADDB_00288 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
MFNHADDB_00289 7.8e-114 ypjP S YpjP-like protein
MFNHADDB_00290 1.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
MFNHADDB_00291 1.7e-75 yphP S Belongs to the UPF0403 family
MFNHADDB_00292 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MFNHADDB_00293 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
MFNHADDB_00294 5.4e-107 ypgQ S phosphohydrolase
MFNHADDB_00295 2.6e-88 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
MFNHADDB_00296 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MFNHADDB_00297 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MFNHADDB_00298 7.9e-31 cspD K Cold-shock protein
MFNHADDB_00299 3.8e-16 degR
MFNHADDB_00300 4.7e-31 S Protein of unknown function (DUF2564)
MFNHADDB_00301 3e-29 ypeQ S Zinc-finger
MFNHADDB_00302 1.8e-134 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
MFNHADDB_00303 2.9e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MFNHADDB_00304 2.7e-67 rnhA 3.1.26.4 L Ribonuclease
MFNHADDB_00306 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
MFNHADDB_00307 2e-07
MFNHADDB_00308 1e-38 ypbS S Protein of unknown function (DUF2533)
MFNHADDB_00309 0.0 ypbR S Dynamin family
MFNHADDB_00310 5.1e-87 ypbQ S protein conserved in bacteria
MFNHADDB_00311 1.5e-205 bcsA Q Naringenin-chalcone synthase
MFNHADDB_00312 3.8e-227 pbuX F xanthine
MFNHADDB_00313 1.1e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MFNHADDB_00314 3.9e-292 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MFNHADDB_00315 1.5e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
MFNHADDB_00316 2.7e-103 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
MFNHADDB_00317 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
MFNHADDB_00318 4.1e-184 ptxS K transcriptional
MFNHADDB_00319 2e-157 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MFNHADDB_00320 5.7e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFNHADDB_00321 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
MFNHADDB_00323 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MFNHADDB_00324 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MFNHADDB_00325 3.7e-91 ypsA S Belongs to the UPF0398 family
MFNHADDB_00326 5.6e-236 yprB L RNase_H superfamily
MFNHADDB_00327 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MFNHADDB_00328 1.1e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
MFNHADDB_00329 7.3e-71 hspX O Belongs to the small heat shock protein (HSP20) family
MFNHADDB_00330 1.2e-48 yppG S YppG-like protein
MFNHADDB_00332 3.4e-11 yppE S Bacterial domain of unknown function (DUF1798)
MFNHADDB_00335 1.8e-186 yppC S Protein of unknown function (DUF2515)
MFNHADDB_00336 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MFNHADDB_00337 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
MFNHADDB_00338 1.8e-92 ypoC
MFNHADDB_00339 1.4e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MFNHADDB_00340 1.3e-128 dnaD L DNA replication protein DnaD
MFNHADDB_00341 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
MFNHADDB_00342 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MFNHADDB_00343 2.2e-79 ypmB S protein conserved in bacteria
MFNHADDB_00344 4.1e-22 ypmA S Protein of unknown function (DUF4264)
MFNHADDB_00345 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MFNHADDB_00346 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MFNHADDB_00347 1e-156 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MFNHADDB_00348 1.3e-148 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MFNHADDB_00349 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MFNHADDB_00350 7.8e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MFNHADDB_00351 6.9e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
MFNHADDB_00352 1.7e-128 bshB1 S proteins, LmbE homologs
MFNHADDB_00353 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
MFNHADDB_00354 4.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MFNHADDB_00355 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
MFNHADDB_00356 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
MFNHADDB_00357 6.1e-143 ypjB S sporulation protein
MFNHADDB_00358 1.1e-99 ypjA S membrane
MFNHADDB_00359 4.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
MFNHADDB_00360 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
MFNHADDB_00361 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
MFNHADDB_00362 1.6e-76 ypiF S Protein of unknown function (DUF2487)
MFNHADDB_00363 1.1e-98 ypiB S Belongs to the UPF0302 family
MFNHADDB_00364 2.7e-233 S COG0457 FOG TPR repeat
MFNHADDB_00365 1.7e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MFNHADDB_00366 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
MFNHADDB_00367 1.4e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MFNHADDB_00368 1.2e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MFNHADDB_00369 4.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MFNHADDB_00370 6.7e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
MFNHADDB_00371 1.1e-112 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
MFNHADDB_00372 2.7e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MFNHADDB_00373 3.1e-292 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MFNHADDB_00374 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MFNHADDB_00375 6.5e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MFNHADDB_00376 1.2e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MFNHADDB_00377 1.1e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
MFNHADDB_00378 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MFNHADDB_00379 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MFNHADDB_00380 1.5e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MFNHADDB_00381 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MFNHADDB_00382 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MFNHADDB_00383 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
MFNHADDB_00384 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MFNHADDB_00385 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MFNHADDB_00386 6e-137 yphF
MFNHADDB_00387 1.6e-18 yphE S Protein of unknown function (DUF2768)
MFNHADDB_00388 1.9e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MFNHADDB_00389 2e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MFNHADDB_00390 7.9e-28 ypzH
MFNHADDB_00391 2.5e-161 seaA S YIEGIA protein
MFNHADDB_00392 6.7e-102 yphA
MFNHADDB_00393 1e-07 S YpzI-like protein
MFNHADDB_00394 1.1e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MFNHADDB_00395 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
MFNHADDB_00396 5.5e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MFNHADDB_00397 1.8e-23 S Family of unknown function (DUF5359)
MFNHADDB_00398 3.5e-112 ypfA M Flagellar protein YcgR
MFNHADDB_00399 1.9e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
MFNHADDB_00400 7.5e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
MFNHADDB_00401 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
MFNHADDB_00402 1.3e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
MFNHADDB_00403 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MFNHADDB_00404 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MFNHADDB_00405 5.2e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
MFNHADDB_00406 8.2e-81 ypbF S Protein of unknown function (DUF2663)
MFNHADDB_00407 1.3e-75 ypbE M Lysin motif
MFNHADDB_00408 2.2e-100 ypbD S metal-dependent membrane protease
MFNHADDB_00409 3.5e-285 recQ 3.6.4.12 L DNA helicase
MFNHADDB_00410 1.9e-200 ypbB 5.1.3.1 S protein conserved in bacteria
MFNHADDB_00411 4.7e-41 fer C Ferredoxin
MFNHADDB_00412 2.2e-86 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MFNHADDB_00413 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFNHADDB_00414 5.9e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MFNHADDB_00415 8.3e-199 rsiX
MFNHADDB_00416 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
MFNHADDB_00417 0.0 resE 2.7.13.3 T Histidine kinase
MFNHADDB_00418 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFNHADDB_00419 6.7e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MFNHADDB_00420 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
MFNHADDB_00421 4.8e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MFNHADDB_00422 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MFNHADDB_00423 1.9e-87 spmB S Spore maturation protein
MFNHADDB_00424 3.5e-103 spmA S Spore maturation protein
MFNHADDB_00425 8.9e-212 dacB 3.4.16.4 M Belongs to the peptidase S11 family
MFNHADDB_00426 7.6e-97 ypuI S Protein of unknown function (DUF3907)
MFNHADDB_00427 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MFNHADDB_00428 6.4e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MFNHADDB_00429 4.6e-91 ypuF S Domain of unknown function (DUF309)
MFNHADDB_00430 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MFNHADDB_00431 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MFNHADDB_00432 1.9e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MFNHADDB_00433 1.7e-114 ribE 2.5.1.9 H Riboflavin synthase
MFNHADDB_00434 1.3e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MFNHADDB_00435 6e-55 ypuD
MFNHADDB_00436 3.5e-97 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MFNHADDB_00437 6.6e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
MFNHADDB_00438 9.1e-16 S SNARE associated Golgi protein
MFNHADDB_00440 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MFNHADDB_00441 1.3e-149 ypuA S Secreted protein
MFNHADDB_00442 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MFNHADDB_00443 1.5e-272 spoVAF EG Stage V sporulation protein AF
MFNHADDB_00444 1.4e-110 spoVAEA S stage V sporulation protein
MFNHADDB_00445 2.2e-57 spoVAEB S stage V sporulation protein
MFNHADDB_00446 9e-192 spoVAD I Stage V sporulation protein AD
MFNHADDB_00447 1.5e-77 spoVAC S stage V sporulation protein AC
MFNHADDB_00448 1e-67 spoVAB S Stage V sporulation protein AB
MFNHADDB_00449 9.6e-112 spoVAA S Stage V sporulation protein AA
MFNHADDB_00450 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MFNHADDB_00451 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MFNHADDB_00452 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
MFNHADDB_00453 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
MFNHADDB_00454 3.8e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MFNHADDB_00455 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MFNHADDB_00456 2.6e-166 xerD L recombinase XerD
MFNHADDB_00457 3.7e-37 S Protein of unknown function (DUF4227)
MFNHADDB_00458 2e-79 fur P Belongs to the Fur family
MFNHADDB_00459 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MFNHADDB_00460 2e-32 yqkK
MFNHADDB_00461 5.5e-242 mleA 1.1.1.38 C malic enzyme
MFNHADDB_00462 3.1e-235 mleN C Na H antiporter
MFNHADDB_00463 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
MFNHADDB_00464 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
MFNHADDB_00465 4.5e-58 ansR K Transcriptional regulator
MFNHADDB_00466 3e-223 yqxK 3.6.4.12 L DNA helicase
MFNHADDB_00467 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
MFNHADDB_00469 4.4e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
MFNHADDB_00470 4e-14 yqkE S Protein of unknown function (DUF3886)
MFNHADDB_00471 2.4e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
MFNHADDB_00472 9.4e-39 yqkC S Protein of unknown function (DUF2552)
MFNHADDB_00473 2.8e-54 yqkB S Belongs to the HesB IscA family
MFNHADDB_00474 4.7e-196 yqkA K GrpB protein
MFNHADDB_00475 8e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
MFNHADDB_00476 3.6e-87 yqjY K acetyltransferase
MFNHADDB_00477 2.2e-49 S YolD-like protein
MFNHADDB_00478 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MFNHADDB_00480 1.7e-224 yqjV G Major Facilitator Superfamily
MFNHADDB_00482 8.8e-71 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MFNHADDB_00483 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
MFNHADDB_00484 7.9e-260 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
MFNHADDB_00485 4.6e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
MFNHADDB_00486 4.1e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
MFNHADDB_00487 1.6e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MFNHADDB_00488 0.0 rocB E arginine degradation protein
MFNHADDB_00489 2.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MFNHADDB_00490 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MFNHADDB_00491 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MFNHADDB_00492 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MFNHADDB_00493 1.6e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MFNHADDB_00494 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MFNHADDB_00495 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MFNHADDB_00496 4.5e-24 yqzJ
MFNHADDB_00497 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MFNHADDB_00498 3.6e-142 yqjF S Uncharacterized conserved protein (COG2071)
MFNHADDB_00499 2.8e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
MFNHADDB_00500 1.6e-288 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MFNHADDB_00501 4.2e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
MFNHADDB_00503 6.8e-98 yqjB S protein conserved in bacteria
MFNHADDB_00504 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
MFNHADDB_00505 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MFNHADDB_00506 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
MFNHADDB_00507 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
MFNHADDB_00508 9.3e-77 yqiW S Belongs to the UPF0403 family
MFNHADDB_00509 2.6e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MFNHADDB_00510 2.3e-207 norA EGP Major facilitator Superfamily
MFNHADDB_00511 2.2e-151 bmrR K helix_turn_helix, mercury resistance
MFNHADDB_00512 2.9e-219 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MFNHADDB_00513 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MFNHADDB_00514 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MFNHADDB_00515 3.7e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MFNHADDB_00516 8.7e-201 buk 2.7.2.7 C Belongs to the acetokinase family
MFNHADDB_00517 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
MFNHADDB_00518 1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
MFNHADDB_00519 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
MFNHADDB_00520 4e-34 yqzF S Protein of unknown function (DUF2627)
MFNHADDB_00521 1.7e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MFNHADDB_00522 6.3e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
MFNHADDB_00523 3.4e-208 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
MFNHADDB_00524 4.1e-209 mmgC I acyl-CoA dehydrogenase
MFNHADDB_00525 1.5e-155 hbdA 1.1.1.157 I Dehydrogenase
MFNHADDB_00526 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
MFNHADDB_00527 3.1e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MFNHADDB_00528 1.7e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
MFNHADDB_00529 6e-27
MFNHADDB_00530 4.3e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MFNHADDB_00532 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MFNHADDB_00533 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
MFNHADDB_00534 4.2e-306 recN L May be involved in recombinational repair of damaged DNA
MFNHADDB_00535 1.7e-78 argR K Regulates arginine biosynthesis genes
MFNHADDB_00536 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
MFNHADDB_00537 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MFNHADDB_00538 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MFNHADDB_00539 1.5e-37 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MFNHADDB_00540 1.9e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MFNHADDB_00541 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MFNHADDB_00542 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MFNHADDB_00543 2.1e-67 yqhY S protein conserved in bacteria
MFNHADDB_00544 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MFNHADDB_00545 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MFNHADDB_00546 3.8e-90 spoIIIAH S SpoIIIAH-like protein
MFNHADDB_00547 3.6e-107 spoIIIAG S stage III sporulation protein AG
MFNHADDB_00548 1.2e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
MFNHADDB_00549 8.4e-197 spoIIIAE S stage III sporulation protein AE
MFNHADDB_00550 2.3e-58 spoIIIAD S Stage III sporulation protein AD
MFNHADDB_00551 7.6e-29 spoIIIAC S stage III sporulation protein AC
MFNHADDB_00552 1.1e-84 spoIIIAB S Stage III sporulation protein
MFNHADDB_00553 8.8e-170 spoIIIAA S stage III sporulation protein AA
MFNHADDB_00554 7.9e-37 yqhV S Protein of unknown function (DUF2619)
MFNHADDB_00555 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MFNHADDB_00556 3.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MFNHADDB_00557 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
MFNHADDB_00558 2.3e-93 yqhR S Conserved membrane protein YqhR
MFNHADDB_00559 4e-173 yqhQ S Protein of unknown function (DUF1385)
MFNHADDB_00560 2.2e-61 yqhP
MFNHADDB_00561 3.4e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
MFNHADDB_00562 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MFNHADDB_00563 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MFNHADDB_00564 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
MFNHADDB_00565 1e-284 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MFNHADDB_00566 1.7e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MFNHADDB_00567 5.3e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
MFNHADDB_00568 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MFNHADDB_00569 3.2e-152 yqhG S Bacterial protein YqhG of unknown function
MFNHADDB_00570 1.2e-24 sinI S Anti-repressor SinI
MFNHADDB_00571 1e-54 sinR K transcriptional
MFNHADDB_00572 2.5e-141 tasA S Cell division protein FtsN
MFNHADDB_00573 1.9e-58 sipW 3.4.21.89 U Signal peptidase
MFNHADDB_00574 1.3e-113 yqxM
MFNHADDB_00575 7.3e-54 yqzG S Protein of unknown function (DUF3889)
MFNHADDB_00576 4.4e-25 yqzE S YqzE-like protein
MFNHADDB_00577 1.8e-44 S ComG operon protein 7
MFNHADDB_00578 1.4e-33 comGF U Putative Competence protein ComGF
MFNHADDB_00579 1.3e-57 comGE
MFNHADDB_00580 7.7e-68 gspH NU protein transport across the cell outer membrane
MFNHADDB_00581 5.2e-47 comGC U Required for transformation and DNA binding
MFNHADDB_00582 2.3e-174 comGB NU COG1459 Type II secretory pathway, component PulF
MFNHADDB_00583 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MFNHADDB_00586 7.2e-175 corA P Mg2 transporter protein
MFNHADDB_00587 7.5e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MFNHADDB_00588 7e-150 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MFNHADDB_00590 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
MFNHADDB_00591 1.8e-37 yqgY S Protein of unknown function (DUF2626)
MFNHADDB_00592 1.2e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
MFNHADDB_00593 8.9e-23 yqgW S Protein of unknown function (DUF2759)
MFNHADDB_00594 6.9e-50 yqgV S Thiamine-binding protein
MFNHADDB_00595 3.9e-198 yqgU
MFNHADDB_00596 2.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
MFNHADDB_00597 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MFNHADDB_00598 5.2e-181 glcK 2.7.1.2 G Glucokinase
MFNHADDB_00599 3.1e-33 yqgQ S Protein conserved in bacteria
MFNHADDB_00600 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
MFNHADDB_00601 2.5e-09 yqgO
MFNHADDB_00602 2e-103 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MFNHADDB_00603 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MFNHADDB_00604 5.1e-201 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
MFNHADDB_00606 9.2e-51 yqzD
MFNHADDB_00607 7.3e-72 yqzC S YceG-like family
MFNHADDB_00608 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MFNHADDB_00609 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MFNHADDB_00610 2.2e-157 pstA P Phosphate transport system permease
MFNHADDB_00611 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
MFNHADDB_00612 6.9e-143 pstS P Phosphate
MFNHADDB_00613 0.0 pbpA 3.4.16.4 M penicillin-binding protein
MFNHADDB_00614 2.5e-231 yqgE EGP Major facilitator superfamily
MFNHADDB_00615 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
MFNHADDB_00616 4e-73 yqgC S protein conserved in bacteria
MFNHADDB_00617 1.5e-130 yqgB S Protein of unknown function (DUF1189)
MFNHADDB_00618 1.2e-46 yqfZ M LysM domain
MFNHADDB_00619 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MFNHADDB_00620 4.3e-62 yqfX S membrane
MFNHADDB_00621 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
MFNHADDB_00622 4.2e-77 zur P Belongs to the Fur family
MFNHADDB_00623 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MFNHADDB_00624 2.1e-36 yqfT S Protein of unknown function (DUF2624)
MFNHADDB_00625 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MFNHADDB_00626 1.7e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MFNHADDB_00628 2.6e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MFNHADDB_00629 1.9e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MFNHADDB_00630 6.1e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
MFNHADDB_00631 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
MFNHADDB_00632 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MFNHADDB_00633 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MFNHADDB_00634 4.5e-88 yaiI S Belongs to the UPF0178 family
MFNHADDB_00635 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MFNHADDB_00636 4.5e-112 ccpN K CBS domain
MFNHADDB_00637 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MFNHADDB_00638 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MFNHADDB_00639 4.1e-144 recO L Involved in DNA repair and RecF pathway recombination
MFNHADDB_00640 8.4e-19 S YqzL-like protein
MFNHADDB_00641 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MFNHADDB_00642 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MFNHADDB_00643 1.6e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MFNHADDB_00644 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MFNHADDB_00645 0.0 yqfF S membrane-associated HD superfamily hydrolase
MFNHADDB_00647 1.1e-175 phoH T Phosphate starvation-inducible protein PhoH
MFNHADDB_00648 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
MFNHADDB_00649 2.7e-45 yqfC S sporulation protein YqfC
MFNHADDB_00650 6e-25 yqfB
MFNHADDB_00651 9.6e-122 yqfA S UPF0365 protein
MFNHADDB_00652 4.5e-228 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
MFNHADDB_00653 2.5e-61 yqeY S Yqey-like protein
MFNHADDB_00654 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MFNHADDB_00655 1.6e-158 yqeW P COG1283 Na phosphate symporter
MFNHADDB_00656 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
MFNHADDB_00657 1.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MFNHADDB_00658 5.4e-175 prmA J Methylates ribosomal protein L11
MFNHADDB_00659 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MFNHADDB_00660 0.0 dnaK O Heat shock 70 kDa protein
MFNHADDB_00661 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MFNHADDB_00662 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MFNHADDB_00663 4.8e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
MFNHADDB_00664 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MFNHADDB_00665 1e-54 yqxA S Protein of unknown function (DUF3679)
MFNHADDB_00666 6.9e-223 spoIIP M stage II sporulation protein P
MFNHADDB_00667 1.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MFNHADDB_00668 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
MFNHADDB_00669 1.1e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
MFNHADDB_00670 4.1e-15 S YqzM-like protein
MFNHADDB_00671 0.0 comEC S Competence protein ComEC
MFNHADDB_00672 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
MFNHADDB_00673 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
MFNHADDB_00674 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MFNHADDB_00675 2.9e-139 yqeM Q Methyltransferase
MFNHADDB_00676 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MFNHADDB_00677 7.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
MFNHADDB_00678 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MFNHADDB_00679 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
MFNHADDB_00680 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MFNHADDB_00681 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MFNHADDB_00682 5.3e-95 yqeG S hydrolase of the HAD superfamily
MFNHADDB_00684 1.8e-141 yqeF E GDSL-like Lipase/Acylhydrolase
MFNHADDB_00685 1.7e-131 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MFNHADDB_00686 5.7e-104 yqeD S SNARE associated Golgi protein
MFNHADDB_00687 5.2e-19 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
MFNHADDB_00688 4.2e-133 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
MFNHADDB_00689 2.3e-133 yqeB
MFNHADDB_00690 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
MFNHADDB_00691 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MFNHADDB_00692 9e-237 yrkQ T Histidine kinase
MFNHADDB_00693 1.1e-127 T Transcriptional regulator
MFNHADDB_00694 4.1e-223 yrkO P Protein of unknown function (DUF418)
MFNHADDB_00695 1.1e-103 yrkN K Acetyltransferase (GNAT) family
MFNHADDB_00696 1.5e-97 ywrO S Flavodoxin-like fold
MFNHADDB_00697 1.1e-78 S Protein of unknown function with HXXEE motif
MFNHADDB_00698 1.7e-100 yrkJ S membrane transporter protein
MFNHADDB_00699 5.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
MFNHADDB_00700 1.4e-206 yrkH P Rhodanese Homology Domain
MFNHADDB_00701 4.6e-97 yrkF OP Belongs to the sulfur carrier protein TusA family
MFNHADDB_00702 2e-65 yrkE O DsrE/DsrF/DrsH-like family
MFNHADDB_00703 7.8e-39 yrkD S protein conserved in bacteria
MFNHADDB_00704 6.4e-107 yrkC G Cupin domain
MFNHADDB_00705 3.1e-150 bltR K helix_turn_helix, mercury resistance
MFNHADDB_00706 2.3e-210 blt EGP Major facilitator Superfamily
MFNHADDB_00707 5.9e-82 bltD 2.3.1.57 K FR47-like protein
MFNHADDB_00708 7.9e-233 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MFNHADDB_00709 3.9e-16 S YrzO-like protein
MFNHADDB_00710 2.3e-168 yrdR EG EamA-like transporter family
MFNHADDB_00711 4.3e-158 yrdQ K Transcriptional regulator
MFNHADDB_00712 6e-199 trkA P Oxidoreductase
MFNHADDB_00713 6.5e-152 czcD P COG1230 Co Zn Cd efflux system component
MFNHADDB_00714 1.3e-66 yodA S tautomerase
MFNHADDB_00715 4.1e-156 gltR K LysR substrate binding domain
MFNHADDB_00716 1.1e-32 C COG2041 Sulfite oxidase and related enzymes
MFNHADDB_00717 8.6e-227 brnQ E Component of the transport system for branched-chain amino acids
MFNHADDB_00718 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
MFNHADDB_00719 2.8e-137 azlC E AzlC protein
MFNHADDB_00720 6.3e-79 bkdR K helix_turn_helix ASNC type
MFNHADDB_00721 1.2e-15 yrdF K ribonuclease inhibitor
MFNHADDB_00722 2.1e-227 cypA C Cytochrome P450
MFNHADDB_00723 1e-99 yrdC 3.5.1.19 Q Isochorismatase family
MFNHADDB_00724 7.5e-54 S Protein of unknown function (DUF2568)
MFNHADDB_00726 1.4e-89 yrdA S DinB family
MFNHADDB_00727 3e-164 aadK G Streptomycin adenylyltransferase
MFNHADDB_00728 9.9e-194 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MFNHADDB_00729 4.5e-146 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MFNHADDB_00730 6.2e-123 yrpD S Domain of unknown function, YrpD
MFNHADDB_00731 4.3e-100 K helix_turn_helix gluconate operon transcriptional repressor
MFNHADDB_00733 7.4e-210 rbtT P Major Facilitator Superfamily
MFNHADDB_00734 5.6e-114 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFNHADDB_00735 3.5e-153 2.2.1.1 G Transketolase, pyrimidine binding domain
MFNHADDB_00736 6.4e-135 tktA 2.2.1.1 G COG3959 Transketolase, N-terminal subunit
MFNHADDB_00737 5.6e-98 flr S Flavin reductase like domain
MFNHADDB_00738 7.2e-118 bmrR K helix_turn_helix, mercury resistance
MFNHADDB_00739 9.9e-48 yjbR S YjbR
MFNHADDB_00740 1.1e-25 epsA I Passenger-associated-transport-repeat
MFNHADDB_00741 9.6e-114 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
MFNHADDB_00742 2.1e-91 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
MFNHADDB_00743 4.5e-188 yrpG C Aldo/keto reductase family
MFNHADDB_00744 1e-224 yraO C Citrate transporter
MFNHADDB_00745 3.4e-163 yraN K Transcriptional regulator
MFNHADDB_00746 5.9e-205 yraM S PrpF protein
MFNHADDB_00747 2.9e-156 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MFNHADDB_00748 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MFNHADDB_00749 6.2e-151 S Alpha beta hydrolase
MFNHADDB_00750 1.7e-60 T sh3 domain protein
MFNHADDB_00751 2.4e-61 T sh3 domain protein
MFNHADDB_00753 3.8e-66 E Glyoxalase-like domain
MFNHADDB_00754 1.5e-36 yraG
MFNHADDB_00755 6.4e-63 yraF M Spore coat protein
MFNHADDB_00756 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MFNHADDB_00757 7.5e-26 yraE
MFNHADDB_00758 1.1e-49 yraD M Spore coat protein
MFNHADDB_00759 2.8e-46 yraB K helix_turn_helix, mercury resistance
MFNHADDB_00760 2.5e-197 adhA 1.1.1.1 C alcohol dehydrogenase
MFNHADDB_00761 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
MFNHADDB_00762 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
MFNHADDB_00763 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
MFNHADDB_00764 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
MFNHADDB_00765 6.9e-81 levE 2.7.1.202 G PTS system mannose fructose sorbose family
MFNHADDB_00766 1.9e-74 levD 2.7.1.202 G PTS system fructose IIA component
MFNHADDB_00767 0.0 levR K PTS system fructose IIA component
MFNHADDB_00768 1e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
MFNHADDB_00769 3.6e-106 yrhP E LysE type translocator
MFNHADDB_00770 1.6e-149 yrhO K Archaeal transcriptional regulator TrmB
MFNHADDB_00771 1.6e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
MFNHADDB_00772 3.8e-151 rsiV S Protein of unknown function (DUF3298)
MFNHADDB_00773 8.3e-247 yrhL I Acyltransferase family
MFNHADDB_00774 6e-58 yrhL I Acyltransferase family
MFNHADDB_00775 1.4e-44 yrhK S YrhK-like protein
MFNHADDB_00776 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
MFNHADDB_00777 1.8e-104 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
MFNHADDB_00778 1.1e-95 yrhH Q methyltransferase
MFNHADDB_00781 1.8e-142 focA P Formate nitrite
MFNHADDB_00783 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
MFNHADDB_00784 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
MFNHADDB_00785 4.1e-78 yrhD S Protein of unknown function (DUF1641)
MFNHADDB_00786 4.6e-35 yrhC S YrhC-like protein
MFNHADDB_00787 7.5e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MFNHADDB_00788 6.8e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
MFNHADDB_00789 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MFNHADDB_00790 7.6e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
MFNHADDB_00791 1e-25 yrzA S Protein of unknown function (DUF2536)
MFNHADDB_00792 4.2e-63 yrrS S Protein of unknown function (DUF1510)
MFNHADDB_00793 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
MFNHADDB_00794 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MFNHADDB_00795 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
MFNHADDB_00796 2.7e-246 yegQ O COG0826 Collagenase and related proteases
MFNHADDB_00797 2.9e-173 yegQ O Peptidase U32
MFNHADDB_00798 2.9e-119 yrrM 2.1.1.104 S O-methyltransferase
MFNHADDB_00799 5.3e-182 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MFNHADDB_00800 1.2e-45 yrzB S Belongs to the UPF0473 family
MFNHADDB_00801 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MFNHADDB_00802 1.7e-41 yrzL S Belongs to the UPF0297 family
MFNHADDB_00803 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MFNHADDB_00804 7.8e-170 yrrI S AI-2E family transporter
MFNHADDB_00805 2.9e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MFNHADDB_00806 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
MFNHADDB_00807 1.8e-108 gluC P ABC transporter
MFNHADDB_00808 7.6e-107 glnP P ABC transporter
MFNHADDB_00809 8e-08 S Protein of unknown function (DUF3918)
MFNHADDB_00810 9.8e-31 yrzR
MFNHADDB_00811 1.7e-81 yrrD S protein conserved in bacteria
MFNHADDB_00812 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MFNHADDB_00813 1.4e-15 S COG0457 FOG TPR repeat
MFNHADDB_00814 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MFNHADDB_00815 2e-211 iscS 2.8.1.7 E Cysteine desulfurase
MFNHADDB_00816 1.2e-70 cymR K Transcriptional regulator
MFNHADDB_00817 3.3e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MFNHADDB_00818 9e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MFNHADDB_00819 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MFNHADDB_00820 1.2e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
MFNHADDB_00822 1.1e-262 lytH 3.5.1.28 M COG3103 SH3 domain protein
MFNHADDB_00823 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MFNHADDB_00824 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MFNHADDB_00825 8.6e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MFNHADDB_00826 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MFNHADDB_00827 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
MFNHADDB_00828 4.3e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
MFNHADDB_00829 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MFNHADDB_00830 1.6e-48 yrzD S Post-transcriptional regulator
MFNHADDB_00831 2.2e-269 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MFNHADDB_00832 1.7e-111 yrbG S membrane
MFNHADDB_00833 3.8e-73 yrzE S Protein of unknown function (DUF3792)
MFNHADDB_00834 1.1e-38 yajC U Preprotein translocase subunit YajC
MFNHADDB_00835 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MFNHADDB_00836 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MFNHADDB_00837 2.6e-18 yrzS S Protein of unknown function (DUF2905)
MFNHADDB_00838 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MFNHADDB_00839 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MFNHADDB_00840 4.8e-93 bofC S BofC C-terminal domain
MFNHADDB_00841 5.3e-253 csbX EGP Major facilitator Superfamily
MFNHADDB_00842 4.1e-192 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
MFNHADDB_00843 6.5e-119 yrzF T serine threonine protein kinase
MFNHADDB_00845 3.1e-51 S Family of unknown function (DUF5412)
MFNHADDB_00846 2e-261 alsT E Sodium alanine symporter
MFNHADDB_00847 1.9e-127 yebC K transcriptional regulatory protein
MFNHADDB_00848 8.5e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MFNHADDB_00849 8.3e-157 safA M spore coat assembly protein SafA
MFNHADDB_00850 9.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MFNHADDB_00851 4.7e-157 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
MFNHADDB_00852 8.9e-303 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
MFNHADDB_00853 3.1e-228 nifS 2.8.1.7 E Cysteine desulfurase
MFNHADDB_00854 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
MFNHADDB_00855 1.7e-162 pheA 4.2.1.51 E Prephenate dehydratase
MFNHADDB_00856 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
MFNHADDB_00857 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MFNHADDB_00858 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
MFNHADDB_00859 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MFNHADDB_00860 4.1e-56 ysxB J ribosomal protein
MFNHADDB_00861 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MFNHADDB_00862 9.2e-161 spoIVFB S Stage IV sporulation protein
MFNHADDB_00863 8.5e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
MFNHADDB_00864 2.5e-144 minD D Belongs to the ParA family
MFNHADDB_00865 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MFNHADDB_00866 1.4e-84 mreD M shape-determining protein
MFNHADDB_00867 1.1e-156 mreC M Involved in formation and maintenance of cell shape
MFNHADDB_00868 1.2e-183 mreB D Rod shape-determining protein MreB
MFNHADDB_00869 6.5e-125 radC E Belongs to the UPF0758 family
MFNHADDB_00870 2.8e-102 maf D septum formation protein Maf
MFNHADDB_00871 1.9e-162 spoIIB S Sporulation related domain
MFNHADDB_00872 3.3e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MFNHADDB_00873 4.7e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MFNHADDB_00874 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MFNHADDB_00875 1.6e-25
MFNHADDB_00876 2.3e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MFNHADDB_00877 1.6e-217 spoVID M stage VI sporulation protein D
MFNHADDB_00878 2.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MFNHADDB_00879 1.8e-181 hemB 4.2.1.24 H Belongs to the ALAD family
MFNHADDB_00880 7.1e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MFNHADDB_00881 3.3e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MFNHADDB_00882 3.6e-146 hemX O cytochrome C
MFNHADDB_00883 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MFNHADDB_00884 5.4e-89 ysxD
MFNHADDB_00885 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
MFNHADDB_00886 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MFNHADDB_00887 2.8e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
MFNHADDB_00888 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MFNHADDB_00889 2.4e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MFNHADDB_00890 1.1e-186 ysoA H Tetratricopeptide repeat
MFNHADDB_00891 1.3e-113 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MFNHADDB_00892 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MFNHADDB_00893 3.7e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MFNHADDB_00894 1.3e-290 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MFNHADDB_00895 9.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MFNHADDB_00896 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
MFNHADDB_00897 0.0 ilvB 2.2.1.6 E Acetolactate synthase
MFNHADDB_00899 3.3e-77 ysnE K acetyltransferase
MFNHADDB_00900 4e-113 ysnF S protein conserved in bacteria
MFNHADDB_00902 7e-92 ysnB S Phosphoesterase
MFNHADDB_00903 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MFNHADDB_00904 9e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MFNHADDB_00905 2.9e-196 gerM S COG5401 Spore germination protein
MFNHADDB_00906 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MFNHADDB_00907 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
MFNHADDB_00908 3.3e-30 gerE K Transcriptional regulator
MFNHADDB_00909 1.6e-76 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
MFNHADDB_00910 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MFNHADDB_00911 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MFNHADDB_00912 2.4e-107 sdhC C succinate dehydrogenase
MFNHADDB_00913 1.2e-79 yslB S Protein of unknown function (DUF2507)
MFNHADDB_00914 6.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MFNHADDB_00915 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MFNHADDB_00916 2e-52 trxA O Belongs to the thioredoxin family
MFNHADDB_00917 1.4e-302 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
MFNHADDB_00919 2.1e-177 etfA C Electron transfer flavoprotein
MFNHADDB_00920 4.5e-135 etfB C Electron transfer flavoprotein
MFNHADDB_00921 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MFNHADDB_00922 2.7e-100 fadR K Transcriptional regulator
MFNHADDB_00923 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MFNHADDB_00924 7.3e-68 yshE S membrane
MFNHADDB_00925 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MFNHADDB_00926 0.0 polX L COG1796 DNA polymerase IV (family X)
MFNHADDB_00927 1.3e-85 cvpA S membrane protein, required for colicin V production
MFNHADDB_00928 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MFNHADDB_00929 5.4e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MFNHADDB_00930 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MFNHADDB_00931 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MFNHADDB_00932 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MFNHADDB_00933 2.6e-32 sspI S Belongs to the SspI family
MFNHADDB_00934 1e-204 ysfB KT regulator
MFNHADDB_00935 6.7e-262 glcD 1.1.3.15 C Glycolate oxidase subunit
MFNHADDB_00936 2.6e-255 glcF C Glycolate oxidase
MFNHADDB_00937 1.7e-41 ysfE 4.4.1.5 E Glyoxalase-like domain
MFNHADDB_00938 0.0 cstA T Carbon starvation protein
MFNHADDB_00939 5.1e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
MFNHADDB_00940 2.9e-143 araQ G transport system permease
MFNHADDB_00941 1.4e-167 araP G carbohydrate transport
MFNHADDB_00942 8.1e-254 araN G carbohydrate transport
MFNHADDB_00943 4.8e-221 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MFNHADDB_00944 2e-146 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
MFNHADDB_00945 5.5e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MFNHADDB_00946 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
MFNHADDB_00947 1.1e-291 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
MFNHADDB_00948 3.1e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
MFNHADDB_00949 6.4e-204 ysdC G COG1363 Cellulase M and related proteins
MFNHADDB_00950 9.2e-68 ysdB S Sigma-w pathway protein YsdB
MFNHADDB_00951 7.5e-45 ysdA S Membrane
MFNHADDB_00952 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MFNHADDB_00953 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MFNHADDB_00954 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MFNHADDB_00956 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MFNHADDB_00957 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MFNHADDB_00958 3.1e-130 lytT T COG3279 Response regulator of the LytR AlgR family
MFNHADDB_00959 0.0 lytS 2.7.13.3 T Histidine kinase
MFNHADDB_00960 7.3e-149 ysaA S HAD-hyrolase-like
MFNHADDB_00961 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MFNHADDB_00962 3.8e-159 ytxC S YtxC-like family
MFNHADDB_00963 4.9e-111 ytxB S SNARE associated Golgi protein
MFNHADDB_00964 6.6e-173 dnaI L Primosomal protein DnaI
MFNHADDB_00965 7.7e-266 dnaB L Membrane attachment protein
MFNHADDB_00966 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MFNHADDB_00967 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MFNHADDB_00968 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MFNHADDB_00969 9.9e-67 ytcD K Transcriptional regulator
MFNHADDB_00970 4.5e-131 ytbD EGP Major facilitator Superfamily
MFNHADDB_00971 8.2e-55 ytbD EGP Major facilitator Superfamily
MFNHADDB_00972 8.9e-161 ytbE S reductase
MFNHADDB_00973 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MFNHADDB_00974 2.8e-106 ytaF P Probably functions as a manganese efflux pump
MFNHADDB_00975 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MFNHADDB_00976 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MFNHADDB_00977 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
MFNHADDB_00978 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFNHADDB_00979 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
MFNHADDB_00980 1.8e-242 icd 1.1.1.42 C isocitrate
MFNHADDB_00981 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
MFNHADDB_00982 5.2e-70 yeaL S membrane
MFNHADDB_00983 2.6e-192 ytvI S sporulation integral membrane protein YtvI
MFNHADDB_00984 4.3e-62 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
MFNHADDB_00985 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MFNHADDB_00986 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MFNHADDB_00987 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MFNHADDB_00988 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MFNHADDB_00989 2.2e-224 ytsJ 1.1.1.38 C Malate dehydrogenase
MFNHADDB_00990 0.0 dnaE 2.7.7.7 L DNA polymerase
MFNHADDB_00991 3.2e-56 ytrH S Sporulation protein YtrH
MFNHADDB_00992 8.2e-69 ytrI
MFNHADDB_00993 9.2e-29
MFNHADDB_00994 5.1e-181 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
MFNHADDB_00995 2.4e-47 ytpI S YtpI-like protein
MFNHADDB_00996 8e-241 ytoI K transcriptional regulator containing CBS domains
MFNHADDB_00997 1.4e-156 ytnM S membrane transporter protein
MFNHADDB_00998 2.5e-236 ytnL 3.5.1.47 E hydrolase activity
MFNHADDB_00999 9e-127 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
MFNHADDB_01000 5.7e-255 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MFNHADDB_01001 2.4e-46 ytnI O COG0695 Glutaredoxin and related proteins
MFNHADDB_01002 7.6e-183 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MFNHADDB_01003 3.9e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MFNHADDB_01004 1.9e-119 tcyM U Binding-protein-dependent transport system inner membrane component
MFNHADDB_01005 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
MFNHADDB_01006 1.9e-147 tcyK M Bacterial periplasmic substrate-binding proteins
MFNHADDB_01007 1.1e-150 tcyK ET Bacterial periplasmic substrate-binding proteins
MFNHADDB_01008 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
MFNHADDB_01009 3.6e-171 ytlI K LysR substrate binding domain
MFNHADDB_01010 1.7e-130 ytkL S Belongs to the UPF0173 family
MFNHADDB_01011 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFNHADDB_01013 1.2e-266 argH 4.3.2.1 E argininosuccinate lyase
MFNHADDB_01014 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MFNHADDB_01015 1.4e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
MFNHADDB_01016 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MFNHADDB_01017 7e-165 ytxK 2.1.1.72 L DNA methylase
MFNHADDB_01018 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MFNHADDB_01019 8.7e-70 ytfJ S Sporulation protein YtfJ
MFNHADDB_01020 8.1e-115 ytfI S Protein of unknown function (DUF2953)
MFNHADDB_01021 8.5e-87 yteJ S RDD family
MFNHADDB_01022 1.1e-178 sppA OU signal peptide peptidase SppA
MFNHADDB_01023 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MFNHADDB_01024 2.2e-311 ytcJ S amidohydrolase
MFNHADDB_01025 2.5e-305 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MFNHADDB_01026 2e-29 sspB S spore protein
MFNHADDB_01027 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MFNHADDB_01028 3.3e-206 iscS2 2.8.1.7 E Cysteine desulfurase
MFNHADDB_01029 1.4e-237 brnQ E Component of the transport system for branched-chain amino acids
MFNHADDB_01030 1.2e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MFNHADDB_01031 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MFNHADDB_01032 1e-108 yttP K Transcriptional regulator
MFNHADDB_01033 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
MFNHADDB_01034 5.3e-309 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
MFNHADDB_01035 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MFNHADDB_01037 8e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MFNHADDB_01038 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MFNHADDB_01039 1.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MFNHADDB_01040 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
MFNHADDB_01041 5.4e-225 acuC BQ histone deacetylase
MFNHADDB_01042 1.4e-125 motS N Flagellar motor protein
MFNHADDB_01043 2.1e-146 motA N flagellar motor
MFNHADDB_01044 1.7e-182 ccpA K catabolite control protein A
MFNHADDB_01045 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MFNHADDB_01046 6.3e-54 ytxJ O Protein of unknown function (DUF2847)
MFNHADDB_01047 6.6e-17 ytxH S COG4980 Gas vesicle protein
MFNHADDB_01048 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MFNHADDB_01049 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MFNHADDB_01050 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
MFNHADDB_01051 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MFNHADDB_01052 2.2e-148 ytpQ S Belongs to the UPF0354 family
MFNHADDB_01053 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MFNHADDB_01054 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
MFNHADDB_01055 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
MFNHADDB_01056 2.2e-51 ytzB S small secreted protein
MFNHADDB_01057 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
MFNHADDB_01058 9.3e-150 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
MFNHADDB_01059 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MFNHADDB_01060 2e-45 ytzH S YtzH-like protein
MFNHADDB_01061 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
MFNHADDB_01062 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MFNHADDB_01063 2.5e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MFNHADDB_01064 8.5e-165 ytlQ
MFNHADDB_01065 1.2e-100 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MFNHADDB_01066 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MFNHADDB_01067 1.7e-270 pepV 3.5.1.18 E Dipeptidase
MFNHADDB_01068 3e-224 pbuO S permease
MFNHADDB_01069 1.1e-201 ythQ U Bacterial ABC transporter protein EcsB
MFNHADDB_01070 4.8e-131 ythP V ABC transporter
MFNHADDB_01071 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
MFNHADDB_01072 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MFNHADDB_01073 3.6e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MFNHADDB_01074 4.9e-241 ytfP S HI0933-like protein
MFNHADDB_01075 3.7e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
MFNHADDB_01076 3.1e-26 yteV S Sporulation protein Cse60
MFNHADDB_01077 4.5e-115 yteU S Integral membrane protein
MFNHADDB_01078 1.1e-255 yteT S Oxidoreductase family, C-terminal alpha/beta domain
MFNHADDB_01079 5.1e-72 yteS G transport
MFNHADDB_01080 1e-217 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
MFNHADDB_01081 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
MFNHADDB_01082 0.0 ytdP K Transcriptional regulator
MFNHADDB_01083 1.5e-288 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
MFNHADDB_01084 1.3e-149 ytcP G COG0395 ABC-type sugar transport system, permease component
MFNHADDB_01085 9e-136 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
MFNHADDB_01086 1.8e-223 bioI 1.14.14.46 C Cytochrome P450
MFNHADDB_01087 8.4e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MFNHADDB_01088 3.8e-125 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MFNHADDB_01089 1.1e-217 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MFNHADDB_01090 1.1e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MFNHADDB_01091 5.2e-141 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MFNHADDB_01092 1.9e-172 ytaP S Acetyl xylan esterase (AXE1)
MFNHADDB_01093 5.6e-189 msmR K Transcriptional regulator
MFNHADDB_01094 1.2e-246 msmE G Bacterial extracellular solute-binding protein
MFNHADDB_01095 1.5e-166 amyD P ABC transporter
MFNHADDB_01096 4.4e-144 amyC P ABC transporter (permease)
MFNHADDB_01097 2.6e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
MFNHADDB_01098 8.1e-51 ytwF P Sulfurtransferase
MFNHADDB_01099 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MFNHADDB_01100 7.7e-55 ytvB S Protein of unknown function (DUF4257)
MFNHADDB_01101 3.9e-142 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MFNHADDB_01102 1.3e-210 yttB EGP Major facilitator Superfamily
MFNHADDB_01103 3.9e-43 yttA 2.7.13.3 S Pfam Transposase IS66
MFNHADDB_01104 0.0 bceB V ABC transporter (permease)
MFNHADDB_01105 1.1e-138 bceA V ABC transporter, ATP-binding protein
MFNHADDB_01106 5.6e-186 T PhoQ Sensor
MFNHADDB_01107 2.6e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFNHADDB_01108 3e-232 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
MFNHADDB_01109 3.1e-127 ytrE V ABC transporter, ATP-binding protein
MFNHADDB_01110 2e-140
MFNHADDB_01111 8.3e-150 P ABC-2 family transporter protein
MFNHADDB_01112 4.2e-161 ytrB P abc transporter atp-binding protein
MFNHADDB_01113 5.1e-66 ytrA K GntR family transcriptional regulator
MFNHADDB_01115 6.7e-41 ytzC S Protein of unknown function (DUF2524)
MFNHADDB_01116 8.1e-190 yhcC S Fe-S oxidoreductase
MFNHADDB_01117 2.4e-104 ytqB J Putative rRNA methylase
MFNHADDB_01118 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
MFNHADDB_01119 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
MFNHADDB_01120 2.1e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MFNHADDB_01121 1.4e-256 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
MFNHADDB_01122 0.0 asnB 6.3.5.4 E Asparagine synthase
MFNHADDB_01123 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MFNHADDB_01124 9.7e-310 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MFNHADDB_01125 1.2e-38 ytmB S Protein of unknown function (DUF2584)
MFNHADDB_01126 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MFNHADDB_01127 2.8e-188 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MFNHADDB_01128 1.4e-144 ytlC P ABC transporter
MFNHADDB_01129 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MFNHADDB_01130 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
MFNHADDB_01131 7.8e-62 ytkC S Bacteriophage holin family
MFNHADDB_01132 2.1e-76 dps P Belongs to the Dps family
MFNHADDB_01134 2e-71 ytkA S YtkA-like
MFNHADDB_01135 4.8e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MFNHADDB_01136 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
MFNHADDB_01137 3.6e-41 rpmE2 J Ribosomal protein L31
MFNHADDB_01138 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
MFNHADDB_01139 1.1e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MFNHADDB_01140 1.1e-24 S Domain of Unknown Function (DUF1540)
MFNHADDB_01141 2.3e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
MFNHADDB_01142 4.4e-231 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MFNHADDB_01143 4.3e-138 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MFNHADDB_01144 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
MFNHADDB_01145 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MFNHADDB_01146 3.2e-275 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MFNHADDB_01147 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MFNHADDB_01148 1.4e-153 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MFNHADDB_01149 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MFNHADDB_01150 1.2e-271 menF 5.4.4.2 HQ Isochorismate synthase
MFNHADDB_01151 9.7e-132 dksA T COG1734 DnaK suppressor protein
MFNHADDB_01152 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
MFNHADDB_01153 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MFNHADDB_01154 1.1e-180 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
MFNHADDB_01155 3.6e-235 ytcC M Glycosyltransferase Family 4
MFNHADDB_01157 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
MFNHADDB_01158 2.9e-215 cotSA M Glycosyl transferases group 1
MFNHADDB_01159 1.3e-204 cotI S Spore coat protein
MFNHADDB_01160 9.9e-77 tspO T membrane
MFNHADDB_01161 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MFNHADDB_01162 1.3e-279 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
MFNHADDB_01163 3.7e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
MFNHADDB_01164 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MFNHADDB_01165 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MFNHADDB_01174 7.8e-08
MFNHADDB_01175 1.3e-09
MFNHADDB_01182 2e-08
MFNHADDB_01187 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
MFNHADDB_01188 3.4e-94 M1-753 M FR47-like protein
MFNHADDB_01189 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
MFNHADDB_01190 1.2e-75 yuaF OU Membrane protein implicated in regulation of membrane protease activity
MFNHADDB_01191 3.9e-84 yuaE S DinB superfamily
MFNHADDB_01192 7.9e-108 yuaD
MFNHADDB_01193 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
MFNHADDB_01194 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
MFNHADDB_01195 1.1e-95 yuaC K Belongs to the GbsR family
MFNHADDB_01196 2.2e-91 yuaB
MFNHADDB_01197 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
MFNHADDB_01198 1.6e-236 ktrB P Potassium
MFNHADDB_01199 1e-38 yiaA S yiaA/B two helix domain
MFNHADDB_01200 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MFNHADDB_01201 3.2e-273 yubD P Major Facilitator Superfamily
MFNHADDB_01202 6.4e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
MFNHADDB_01204 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MFNHADDB_01205 4.5e-195 yubA S transporter activity
MFNHADDB_01206 3.3e-183 ygjR S Oxidoreductase
MFNHADDB_01207 1.4e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
MFNHADDB_01208 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
MFNHADDB_01209 1.3e-281 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MFNHADDB_01210 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
MFNHADDB_01211 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
MFNHADDB_01212 5.1e-239 mcpA NT chemotaxis protein
MFNHADDB_01213 2.2e-295 mcpA NT chemotaxis protein
MFNHADDB_01214 9.9e-219 mcpA NT chemotaxis protein
MFNHADDB_01215 9.3e-225 mcpA NT chemotaxis protein
MFNHADDB_01216 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
MFNHADDB_01217 2.3e-35
MFNHADDB_01218 2.1e-72 yugU S Uncharacterised protein family UPF0047
MFNHADDB_01219 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
MFNHADDB_01220 8.4e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
MFNHADDB_01221 1.4e-116 yugP S Zn-dependent protease
MFNHADDB_01222 2.3e-38
MFNHADDB_01223 1.1e-53 mstX S Membrane-integrating protein Mistic
MFNHADDB_01224 8.2e-182 yugO P COG1226 Kef-type K transport systems
MFNHADDB_01225 1.4e-71 yugN S YugN-like family
MFNHADDB_01227 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
MFNHADDB_01228 4e-228 yugK C Dehydrogenase
MFNHADDB_01229 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
MFNHADDB_01230 1.1e-34 yuzA S Domain of unknown function (DUF378)
MFNHADDB_01231 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
MFNHADDB_01232 6.2e-199 yugH 2.6.1.1 E Aminotransferase
MFNHADDB_01233 1.6e-85 alaR K Transcriptional regulator
MFNHADDB_01234 4.9e-156 yugF I Hydrolase
MFNHADDB_01235 4.6e-39 yugE S Domain of unknown function (DUF1871)
MFNHADDB_01236 5.4e-225 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MFNHADDB_01237 4.6e-233 T PhoQ Sensor
MFNHADDB_01238 1.8e-68 kapB G Kinase associated protein B
MFNHADDB_01239 1.9e-115 kapD L the KinA pathway to sporulation
MFNHADDB_01241 2.1e-183 yuxJ EGP Major facilitator Superfamily
MFNHADDB_01242 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
MFNHADDB_01243 6.3e-75 yuxK S protein conserved in bacteria
MFNHADDB_01244 6.3e-78 yufK S Family of unknown function (DUF5366)
MFNHADDB_01245 6.4e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MFNHADDB_01246 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
MFNHADDB_01247 9.9e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
MFNHADDB_01248 5.4e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
MFNHADDB_01249 2.5e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
MFNHADDB_01250 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
MFNHADDB_01251 8.2e-233 maeN C COG3493 Na citrate symporter
MFNHADDB_01252 3.2e-14
MFNHADDB_01253 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MFNHADDB_01254 3.5e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MFNHADDB_01255 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MFNHADDB_01256 7.1e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MFNHADDB_01257 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MFNHADDB_01258 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MFNHADDB_01259 6.7e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
MFNHADDB_01260 1.8e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
MFNHADDB_01261 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MFNHADDB_01262 9.9e-263 comP 2.7.13.3 T Histidine kinase
MFNHADDB_01264 3e-141 comQ H Belongs to the FPP GGPP synthase family
MFNHADDB_01266 3.8e-23 yuzC
MFNHADDB_01267 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
MFNHADDB_01268 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MFNHADDB_01269 1.2e-102 pncA Q COG1335 Amidases related to nicotinamidase
MFNHADDB_01270 5.1e-66 yueI S Protein of unknown function (DUF1694)
MFNHADDB_01271 7.4e-39 yueH S YueH-like protein
MFNHADDB_01272 6.6e-31 yueG S Spore germination protein gerPA/gerPF
MFNHADDB_01273 2.7e-189 yueF S transporter activity
MFNHADDB_01274 5.2e-71 S Protein of unknown function (DUF2283)
MFNHADDB_01275 2.9e-24 S Protein of unknown function (DUF2642)
MFNHADDB_01276 4.1e-95 yueE S phosphohydrolase
MFNHADDB_01277 7.1e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFNHADDB_01278 3.3e-64 yueC S Family of unknown function (DUF5383)
MFNHADDB_01279 0.0 esaA S type VII secretion protein EsaA
MFNHADDB_01280 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MFNHADDB_01281 5.2e-211 essB S WXG100 protein secretion system (Wss), protein YukC
MFNHADDB_01282 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
MFNHADDB_01283 2.8e-45 esxA S Belongs to the WXG100 family
MFNHADDB_01284 1.4e-226 yukF QT Transcriptional regulator
MFNHADDB_01285 1.8e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
MFNHADDB_01286 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
MFNHADDB_01287 5e-36 mbtH S MbtH-like protein
MFNHADDB_01288 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFNHADDB_01289 2.9e-176 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
MFNHADDB_01290 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
MFNHADDB_01291 2.3e-226 entC 5.4.4.2 HQ Isochorismate synthase
MFNHADDB_01292 3.6e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MFNHADDB_01293 9.6e-166 besA S Putative esterase
MFNHADDB_01294 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
MFNHADDB_01295 1.1e-93 bioY S Biotin biosynthesis protein
MFNHADDB_01296 3.9e-211 yuiF S antiporter
MFNHADDB_01297 3.4e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MFNHADDB_01298 1.2e-77 yuiD S protein conserved in bacteria
MFNHADDB_01299 1.1e-116 yuiC S protein conserved in bacteria
MFNHADDB_01300 3.2e-26 yuiB S Putative membrane protein
MFNHADDB_01301 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
MFNHADDB_01302 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
MFNHADDB_01304 6e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MFNHADDB_01305 3.8e-116 paiB K Putative FMN-binding domain
MFNHADDB_01306 1.4e-71 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MFNHADDB_01307 3.7e-63 erpA S Belongs to the HesB IscA family
MFNHADDB_01308 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MFNHADDB_01309 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MFNHADDB_01310 3.2e-39 yuzB S Belongs to the UPF0349 family
MFNHADDB_01311 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
MFNHADDB_01312 1.1e-55 yuzD S protein conserved in bacteria
MFNHADDB_01313 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
MFNHADDB_01314 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
MFNHADDB_01315 1.6e-171 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MFNHADDB_01316 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MFNHADDB_01317 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
MFNHADDB_01318 2.9e-198 yutH S Spore coat protein
MFNHADDB_01319 3.3e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
MFNHADDB_01320 1.2e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MFNHADDB_01321 1e-75 yutE S Protein of unknown function DUF86
MFNHADDB_01322 9.7e-48 yutD S protein conserved in bacteria
MFNHADDB_01323 2.4e-110 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MFNHADDB_01324 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MFNHADDB_01325 3.8e-195 lytH M Peptidase, M23
MFNHADDB_01326 3.2e-133 yunB S Sporulation protein YunB (Spo_YunB)
MFNHADDB_01327 4.8e-48 yunC S Domain of unknown function (DUF1805)
MFNHADDB_01328 1.9e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MFNHADDB_01329 2.9e-140 yunE S membrane transporter protein
MFNHADDB_01330 4.3e-171 yunF S Protein of unknown function DUF72
MFNHADDB_01331 1.4e-59 yunG
MFNHADDB_01332 1.9e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MFNHADDB_01333 2.7e-299 pucR QT COG2508 Regulator of polyketide synthase expression
MFNHADDB_01334 2e-234 pbuX F Permease family
MFNHADDB_01335 4.8e-222 pbuX F xanthine
MFNHADDB_01336 2.6e-280 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
MFNHADDB_01337 6.6e-54 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
MFNHADDB_01339 1.8e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MFNHADDB_01340 1.2e-29 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MFNHADDB_01341 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MFNHADDB_01342 4.9e-143 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MFNHADDB_01343 7.6e-109 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
MFNHADDB_01344 3.8e-187 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MFNHADDB_01346 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MFNHADDB_01347 1.5e-236 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MFNHADDB_01348 7.7e-168 bsn L Ribonuclease
MFNHADDB_01349 5.9e-205 msmX P Belongs to the ABC transporter superfamily
MFNHADDB_01350 1.1e-135 yurK K UTRA
MFNHADDB_01351 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
MFNHADDB_01352 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
MFNHADDB_01353 6.9e-156 yurN G Binding-protein-dependent transport system inner membrane component
MFNHADDB_01354 1.5e-239 yurO G COG1653 ABC-type sugar transport system, periplasmic component
MFNHADDB_01355 2.6e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MFNHADDB_01356 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
MFNHADDB_01357 6.4e-207 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
MFNHADDB_01359 1e-41
MFNHADDB_01360 3.5e-271 sufB O FeS cluster assembly
MFNHADDB_01361 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
MFNHADDB_01362 3.6e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MFNHADDB_01363 1.4e-245 sufD O assembly protein SufD
MFNHADDB_01364 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MFNHADDB_01365 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MFNHADDB_01366 4.2e-147 metQ P Belongs to the NlpA lipoprotein family
MFNHADDB_01367 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
MFNHADDB_01368 6.3e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MFNHADDB_01369 2.4e-56 yusD S SCP-2 sterol transfer family
MFNHADDB_01370 1.2e-54 traF CO Thioredoxin
MFNHADDB_01371 2.1e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
MFNHADDB_01372 1.1e-39 yusG S Protein of unknown function (DUF2553)
MFNHADDB_01373 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MFNHADDB_01374 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
MFNHADDB_01375 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
MFNHADDB_01376 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
MFNHADDB_01377 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
MFNHADDB_01378 8.1e-09 S YuzL-like protein
MFNHADDB_01379 7.1e-164 fadM E Proline dehydrogenase
MFNHADDB_01380 5.1e-40
MFNHADDB_01381 5.4e-53 yusN M Coat F domain
MFNHADDB_01382 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
MFNHADDB_01383 8.5e-293 yusP P Major facilitator superfamily
MFNHADDB_01384 7.1e-65 yusQ S Tautomerase enzyme
MFNHADDB_01385 1.3e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MFNHADDB_01386 5.7e-158 yusT K LysR substrate binding domain
MFNHADDB_01387 3.8e-47 yusU S Protein of unknown function (DUF2573)
MFNHADDB_01388 1e-153 yusV 3.6.3.34 HP ABC transporter
MFNHADDB_01389 9.6e-66 S YusW-like protein
MFNHADDB_01390 7.2e-301 pepF2 E COG1164 Oligoendopeptidase F
MFNHADDB_01391 8.9e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MFNHADDB_01392 4.7e-79 dps P Ferritin-like domain
MFNHADDB_01393 4.7e-236 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MFNHADDB_01394 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFNHADDB_01395 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
MFNHADDB_01396 4.3e-158 yuxN K Transcriptional regulator
MFNHADDB_01397 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MFNHADDB_01398 2.3e-24 S Protein of unknown function (DUF3970)
MFNHADDB_01399 3.7e-247 gerAA EG Spore germination protein
MFNHADDB_01400 9.1e-198 gerAB E Spore germination protein
MFNHADDB_01401 6e-189 gerAC S Spore germination B3/ GerAC like, C-terminal
MFNHADDB_01402 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MFNHADDB_01403 3.5e-186 vraS 2.7.13.3 T Histidine kinase
MFNHADDB_01404 9.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
MFNHADDB_01405 9.3e-129 liaG S Putative adhesin
MFNHADDB_01406 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MFNHADDB_01407 5.6e-62 liaI S membrane
MFNHADDB_01408 4.8e-227 yvqJ EGP Major facilitator Superfamily
MFNHADDB_01409 6.5e-102 yvqK 2.5.1.17 S Adenosyltransferase
MFNHADDB_01410 3.7e-246 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MFNHADDB_01411 1.9e-184 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFNHADDB_01412 2.6e-169 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MFNHADDB_01413 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MFNHADDB_01414 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
MFNHADDB_01415 0.0 T PhoQ Sensor
MFNHADDB_01416 3.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFNHADDB_01417 3.6e-22
MFNHADDB_01418 1.6e-97 yvrI K RNA polymerase
MFNHADDB_01419 2.4e-19 S YvrJ protein family
MFNHADDB_01420 7.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
MFNHADDB_01421 1.3e-64 yvrL S Regulatory protein YrvL
MFNHADDB_01422 4e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
MFNHADDB_01423 1.6e-123 macB V ABC transporter, ATP-binding protein
MFNHADDB_01424 7.6e-174 M Efflux transporter rnd family, mfp subunit
MFNHADDB_01426 4.9e-148 fhuC 3.6.3.34 HP ABC transporter
MFNHADDB_01427 6.9e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFNHADDB_01428 4.6e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFNHADDB_01429 1.2e-177 fhuD P ABC transporter
MFNHADDB_01430 4.9e-236 yvsH E Arginine ornithine antiporter
MFNHADDB_01431 6.5e-16 S Small spore protein J (Spore_SspJ)
MFNHADDB_01432 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
MFNHADDB_01433 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MFNHADDB_01434 2e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
MFNHADDB_01435 1.6e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
MFNHADDB_01436 1.7e-117 modB P COG4149 ABC-type molybdate transport system, permease component
MFNHADDB_01437 1.1e-155 yvgN S reductase
MFNHADDB_01438 5.4e-86 yvgO
MFNHADDB_01439 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
MFNHADDB_01440 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MFNHADDB_01441 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MFNHADDB_01442 0.0 helD 3.6.4.12 L DNA helicase
MFNHADDB_01444 1.6e-106 yvgT S membrane
MFNHADDB_01445 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
MFNHADDB_01446 1.6e-104 bdbD O Thioredoxin
MFNHADDB_01447 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MFNHADDB_01448 0.0 copA 3.6.3.54 P P-type ATPase
MFNHADDB_01449 5.9e-29 copZ P Copper resistance protein CopZ
MFNHADDB_01450 2.2e-48 csoR S transcriptional
MFNHADDB_01451 1.1e-195 yvaA 1.1.1.371 S Oxidoreductase
MFNHADDB_01452 7e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MFNHADDB_01453 0.0 yvaC S Fusaric acid resistance protein-like
MFNHADDB_01454 5.7e-73 yvaD S Family of unknown function (DUF5360)
MFNHADDB_01455 1.8e-54 yvaE P Small Multidrug Resistance protein
MFNHADDB_01456 1.2e-97 K Bacterial regulatory proteins, tetR family
MFNHADDB_01457 1e-129 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MFNHADDB_01459 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MFNHADDB_01460 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MFNHADDB_01461 5.6e-143 est 3.1.1.1 S Carboxylesterase
MFNHADDB_01462 2.4e-23 secG U Preprotein translocase subunit SecG
MFNHADDB_01463 4.2e-149 yvaM S Serine aminopeptidase, S33
MFNHADDB_01464 7.5e-36 yvzC K Transcriptional
MFNHADDB_01465 4e-69 K transcriptional
MFNHADDB_01466 1.2e-68 yvaO K Cro/C1-type HTH DNA-binding domain
MFNHADDB_01467 2.2e-54 yodB K transcriptional
MFNHADDB_01468 7.7e-204 NT chemotaxis protein
MFNHADDB_01469 2.4e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MFNHADDB_01470 7.2e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MFNHADDB_01471 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MFNHADDB_01472 7.5e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MFNHADDB_01473 3.3e-60 yvbF K Belongs to the GbsR family
MFNHADDB_01474 1.1e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MFNHADDB_01475 2.3e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MFNHADDB_01476 2.3e-111 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MFNHADDB_01477 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MFNHADDB_01478 3.5e-97 yvbF K Belongs to the GbsR family
MFNHADDB_01479 2.4e-102 yvbG U UPF0056 membrane protein
MFNHADDB_01480 6.2e-111 yvbH S YvbH-like oligomerisation region
MFNHADDB_01481 3e-122 exoY M Membrane
MFNHADDB_01482 0.0 tcaA S response to antibiotic
MFNHADDB_01483 1.3e-81 yvbK 3.1.3.25 K acetyltransferase
MFNHADDB_01484 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MFNHADDB_01485 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
MFNHADDB_01486 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MFNHADDB_01487 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MFNHADDB_01488 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MFNHADDB_01489 1.8e-184 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MFNHADDB_01490 1.6e-252 araE EGP Major facilitator Superfamily
MFNHADDB_01491 5.5e-203 araR K transcriptional
MFNHADDB_01492 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MFNHADDB_01494 4.3e-158 yvbU K Transcriptional regulator
MFNHADDB_01495 7.2e-156 yvbV EG EamA-like transporter family
MFNHADDB_01496 3.7e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
MFNHADDB_01497 1.6e-191 yvbX S Glycosyl hydrolase
MFNHADDB_01498 3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MFNHADDB_01499 2.7e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MFNHADDB_01500 2.2e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MFNHADDB_01501 3.8e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MFNHADDB_01502 4.3e-195 desK 2.7.13.3 T Histidine kinase
MFNHADDB_01503 7.6e-132 yvfS V COG0842 ABC-type multidrug transport system, permease component
MFNHADDB_01504 6.6e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
MFNHADDB_01505 2.6e-157 rsbQ S Alpha/beta hydrolase family
MFNHADDB_01506 1.4e-199 rsbU 3.1.3.3 T response regulator
MFNHADDB_01507 2.6e-252 galA 3.2.1.89 G arabinogalactan
MFNHADDB_01508 0.0 lacA 3.2.1.23 G beta-galactosidase
MFNHADDB_01509 3.2e-150 ganQ P transport
MFNHADDB_01510 1.3e-232 malC P COG1175 ABC-type sugar transport systems, permease components
MFNHADDB_01511 2.9e-232 cycB G COG2182 Maltose-binding periplasmic proteins domains
MFNHADDB_01512 1.8e-184 lacR K Transcriptional regulator
MFNHADDB_01513 2.7e-113 yvfI K COG2186 Transcriptional regulators
MFNHADDB_01514 2.6e-308 yvfH C L-lactate permease
MFNHADDB_01515 1.1e-239 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MFNHADDB_01516 1e-31 yvfG S YvfG protein
MFNHADDB_01517 9.2e-186 yvfF GM Exopolysaccharide biosynthesis protein
MFNHADDB_01518 2.5e-222 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
MFNHADDB_01519 1.1e-52 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
MFNHADDB_01520 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MFNHADDB_01521 2.4e-257 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MFNHADDB_01522 9.8e-194 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
MFNHADDB_01523 9.2e-203 epsI GM pyruvyl transferase
MFNHADDB_01524 5.8e-194 epsH GT2 S Glycosyltransferase like family 2
MFNHADDB_01525 1.1e-206 epsG S EpsG family
MFNHADDB_01526 5.3e-220 epsF GT4 M Glycosyl transferases group 1
MFNHADDB_01527 1.2e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MFNHADDB_01528 2e-224 epsD GT4 M Glycosyl transferase 4-like
MFNHADDB_01529 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
MFNHADDB_01530 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
MFNHADDB_01531 4e-122 ywqC M biosynthesis protein
MFNHADDB_01532 6.3e-76 slr K transcriptional
MFNHADDB_01533 1.8e-281 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
MFNHADDB_01535 1.7e-92 padC Q Phenolic acid decarboxylase
MFNHADDB_01536 6.5e-73 MA20_18690 S Protein of unknown function (DUF3237)
MFNHADDB_01537 2.2e-125 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MFNHADDB_01538 2.1e-260 pbpE V Beta-lactamase
MFNHADDB_01539 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
MFNHADDB_01540 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
MFNHADDB_01541 1.8e-295 yveA E amino acid
MFNHADDB_01542 2.6e-106 yvdT K Transcriptional regulator
MFNHADDB_01543 1.5e-50 ykkC P Small Multidrug Resistance protein
MFNHADDB_01544 4.1e-50 sugE P Small Multidrug Resistance protein
MFNHADDB_01545 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
MFNHADDB_01546 3.2e-269 ygaK C COG0277 FAD FMN-containing dehydrogenases
MFNHADDB_01547 2.8e-182 S Patatin-like phospholipase
MFNHADDB_01549 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MFNHADDB_01550 2.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
MFNHADDB_01551 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
MFNHADDB_01552 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
MFNHADDB_01553 1.2e-152 malA S Protein of unknown function (DUF1189)
MFNHADDB_01554 6.2e-146 malD P transport
MFNHADDB_01555 1.3e-243 malC P COG1175 ABC-type sugar transport systems, permease components
MFNHADDB_01556 6.9e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
MFNHADDB_01557 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
MFNHADDB_01558 8.8e-173 yvdE K Transcriptional regulator
MFNHADDB_01559 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
MFNHADDB_01560 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
MFNHADDB_01561 6.2e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
MFNHADDB_01562 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
MFNHADDB_01563 5.1e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFNHADDB_01564 0.0 yxdM V ABC transporter (permease)
MFNHADDB_01565 5.6e-141 yvcR V ABC transporter, ATP-binding protein
MFNHADDB_01566 1.1e-195 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
MFNHADDB_01567 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFNHADDB_01568 1.8e-33
MFNHADDB_01569 4e-144 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
MFNHADDB_01570 1.6e-36 crh G Phosphocarrier protein Chr
MFNHADDB_01571 1.4e-170 whiA K May be required for sporulation
MFNHADDB_01572 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MFNHADDB_01573 5.7e-166 rapZ S Displays ATPase and GTPase activities
MFNHADDB_01574 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MFNHADDB_01575 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MFNHADDB_01576 1.8e-97 usp CBM50 M protein conserved in bacteria
MFNHADDB_01577 2.9e-276 S COG0457 FOG TPR repeat
MFNHADDB_01578 0.0 msbA2 3.6.3.44 V ABC transporter
MFNHADDB_01580 0.0
MFNHADDB_01581 4.6e-121
MFNHADDB_01582 8e-114 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
MFNHADDB_01583 1.4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MFNHADDB_01584 8.4e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MFNHADDB_01585 6.2e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MFNHADDB_01586 4.7e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MFNHADDB_01587 2.2e-227 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MFNHADDB_01588 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MFNHADDB_01589 2.4e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MFNHADDB_01590 3.8e-139 yvpB NU protein conserved in bacteria
MFNHADDB_01591 5.1e-119 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
MFNHADDB_01592 1.6e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
MFNHADDB_01593 3.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MFNHADDB_01594 1.6e-163 yvoD P COG0370 Fe2 transport system protein B
MFNHADDB_01595 1.2e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MFNHADDB_01596 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MFNHADDB_01597 2.5e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MFNHADDB_01598 5.6e-127 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MFNHADDB_01599 8.1e-134 yvoA K transcriptional
MFNHADDB_01600 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
MFNHADDB_01601 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
MFNHADDB_01602 4.1e-231 cypX 1.14.15.13 C Cytochrome P450
MFNHADDB_01603 3.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
MFNHADDB_01604 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
MFNHADDB_01605 3.9e-202 yvmA EGP Major facilitator Superfamily
MFNHADDB_01606 1.2e-50 yvlD S Membrane
MFNHADDB_01607 2.6e-26 pspB KT PspC domain
MFNHADDB_01608 7.5e-168 yvlB S Putative adhesin
MFNHADDB_01609 8e-49 yvlA
MFNHADDB_01610 6.7e-34 yvkN
MFNHADDB_01611 1.2e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MFNHADDB_01612 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MFNHADDB_01613 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MFNHADDB_01614 1.2e-30 csbA S protein conserved in bacteria
MFNHADDB_01615 0.0 yvkC 2.7.9.2 GT Phosphotransferase
MFNHADDB_01616 7.8e-100 yvkB K Transcriptional regulator
MFNHADDB_01617 3.3e-226 yvkA EGP Major facilitator Superfamily
MFNHADDB_01618 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MFNHADDB_01619 5.3e-56 swrA S Swarming motility protein
MFNHADDB_01620 1.5e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
MFNHADDB_01621 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MFNHADDB_01622 2.7e-123 ftsE D cell division ATP-binding protein FtsE
MFNHADDB_01623 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
MFNHADDB_01624 3.5e-141 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
MFNHADDB_01625 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MFNHADDB_01626 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MFNHADDB_01627 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MFNHADDB_01628 2.8e-66
MFNHADDB_01629 1.9e-08 fliT S bacterial-type flagellum organization
MFNHADDB_01630 2.5e-68 fliS N flagellar protein FliS
MFNHADDB_01631 2.2e-247 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MFNHADDB_01632 3e-51 flaG N flagellar protein FlaG
MFNHADDB_01633 5.9e-93 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MFNHADDB_01634 6.3e-29 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MFNHADDB_01635 8e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MFNHADDB_01636 1.3e-49 yviE
MFNHADDB_01637 7.8e-155 flgL N Belongs to the bacterial flagellin family
MFNHADDB_01638 1.2e-264 flgK N flagellar hook-associated protein
MFNHADDB_01639 4.1e-78 flgN NOU FlgN protein
MFNHADDB_01640 1.6e-39 flgM KNU Negative regulator of flagellin synthesis
MFNHADDB_01641 7e-74 yvyF S flagellar protein
MFNHADDB_01642 2.3e-125 comFC S Phosphoribosyl transferase domain
MFNHADDB_01643 3.7e-45 comFB S Late competence development protein ComFB
MFNHADDB_01644 4e-267 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MFNHADDB_01645 2.1e-154 degV S protein conserved in bacteria
MFNHADDB_01646 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MFNHADDB_01647 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MFNHADDB_01648 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
MFNHADDB_01649 6e-163 yvhJ K Transcriptional regulator
MFNHADDB_01650 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MFNHADDB_01651 1.1e-233 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
MFNHADDB_01652 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
MFNHADDB_01653 1.5e-113 tuaF M protein involved in exopolysaccharide biosynthesis
MFNHADDB_01654 1.8e-262 tuaE M Teichuronic acid biosynthesis protein
MFNHADDB_01655 2.6e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MFNHADDB_01656 3.8e-218 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
MFNHADDB_01657 4.4e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MFNHADDB_01658 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MFNHADDB_01659 2.8e-93 M Glycosyltransferase like family 2
MFNHADDB_01660 9.1e-209 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MFNHADDB_01661 0.0 lytB 3.5.1.28 D Stage II sporulation protein
MFNHADDB_01662 1e-11
MFNHADDB_01663 2.7e-158 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MFNHADDB_01664 1.2e-216 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MFNHADDB_01665 2.1e-88 M Glycosyltransferase like family 2
MFNHADDB_01666 3.5e-99 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
MFNHADDB_01667 1.1e-22 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
MFNHADDB_01668 4.5e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MFNHADDB_01669 3.5e-267 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MFNHADDB_01670 1e-132 tagG GM Transport permease protein
MFNHADDB_01671 1.3e-88
MFNHADDB_01672 2.1e-55
MFNHADDB_01673 9.6e-209 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MFNHADDB_01674 6.5e-89 ggaA M Glycosyltransferase like family 2
MFNHADDB_01675 1.5e-145 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MFNHADDB_01676 2.1e-56 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
MFNHADDB_01677 9.2e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MFNHADDB_01678 1.5e-105 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MFNHADDB_01679 2.6e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
MFNHADDB_01680 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
MFNHADDB_01681 2e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MFNHADDB_01682 2.5e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MFNHADDB_01683 2e-214 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MFNHADDB_01684 1.3e-189 pmi 5.3.1.8 G mannose-6-phosphate isomerase
MFNHADDB_01685 1.8e-265 gerBA EG Spore germination protein
MFNHADDB_01686 1.3e-199 gerBB E Spore germination protein
MFNHADDB_01687 9.9e-216 gerAC S Spore germination protein
MFNHADDB_01688 1.2e-247 ywtG EGP Major facilitator Superfamily
MFNHADDB_01689 3.2e-170 ywtF K Transcriptional regulator
MFNHADDB_01690 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
MFNHADDB_01691 4.5e-239 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MFNHADDB_01692 1.4e-20 ywtC
MFNHADDB_01693 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MFNHADDB_01694 8.6e-70 pgsC S biosynthesis protein
MFNHADDB_01695 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
MFNHADDB_01696 3.6e-177 rbsR K transcriptional
MFNHADDB_01697 2.7e-160 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MFNHADDB_01698 1.4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MFNHADDB_01699 2.5e-275 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MFNHADDB_01700 9.3e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
MFNHADDB_01701 2.4e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
MFNHADDB_01702 1.2e-91 batE T Sh3 type 3 domain protein
MFNHADDB_01703 8e-48 ywsA S Protein of unknown function (DUF3892)
MFNHADDB_01704 4.4e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
MFNHADDB_01705 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
MFNHADDB_01706 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MFNHADDB_01707 1.1e-169 alsR K LysR substrate binding domain
MFNHADDB_01708 1.9e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MFNHADDB_01709 3.1e-124 ywrJ
MFNHADDB_01710 7.6e-131 cotB
MFNHADDB_01711 1.3e-209 cotH M Spore Coat
MFNHADDB_01712 3.7e-12
MFNHADDB_01713 2.4e-110 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MFNHADDB_01714 5e-54 S Domain of unknown function (DUF4181)
MFNHADDB_01715 1.4e-303 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MFNHADDB_01716 8e-82 ywrC K Transcriptional regulator
MFNHADDB_01717 1.6e-103 ywrB P Chromate transporter
MFNHADDB_01718 6.4e-88 ywrA P COG2059 Chromate transport protein ChrA
MFNHADDB_01720 3.3e-100 ywqN S NAD(P)H-dependent
MFNHADDB_01721 4.9e-162 K Transcriptional regulator
MFNHADDB_01722 3.1e-122 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
MFNHADDB_01723 1.7e-98
MFNHADDB_01725 7.4e-51
MFNHADDB_01726 1.1e-75
MFNHADDB_01727 8.2e-239 ywqJ S Pre-toxin TG
MFNHADDB_01728 2e-37 ywqI S Family of unknown function (DUF5344)
MFNHADDB_01729 1e-19 S Domain of unknown function (DUF5082)
MFNHADDB_01730 5.4e-152 ywqG S Domain of unknown function (DUF1963)
MFNHADDB_01731 3.4e-247 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MFNHADDB_01732 7.4e-138 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
MFNHADDB_01733 2.2e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
MFNHADDB_01734 2e-116 ywqC M biosynthesis protein
MFNHADDB_01735 1.2e-17
MFNHADDB_01736 1.2e-307 ywqB S SWIM zinc finger
MFNHADDB_01737 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MFNHADDB_01738 1.3e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
MFNHADDB_01739 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
MFNHADDB_01740 9.8e-58 ssbB L Single-stranded DNA-binding protein
MFNHADDB_01741 1.9e-65 ywpG
MFNHADDB_01742 6.9e-66 ywpF S YwpF-like protein
MFNHADDB_01743 2.6e-49 srtA 3.4.22.70 M Sortase family
MFNHADDB_01744 1e-39 ywpD T PhoQ Sensor
MFNHADDB_01745 1.4e-51 ywpD T Histidine kinase
MFNHADDB_01746 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MFNHADDB_01747 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MFNHADDB_01748 2.6e-197 S aspartate phosphatase
MFNHADDB_01749 2.6e-141 flhP N flagellar basal body
MFNHADDB_01750 1.4e-123 flhO N flagellar basal body
MFNHADDB_01751 3.5e-180 mbl D Rod shape-determining protein
MFNHADDB_01752 3e-44 spoIIID K Stage III sporulation protein D
MFNHADDB_01753 2.1e-70 ywoH K COG1846 Transcriptional regulators
MFNHADDB_01754 2.7e-211 ywoG EGP Major facilitator Superfamily
MFNHADDB_01755 8e-231 ywoF P Right handed beta helix region
MFNHADDB_01756 1.4e-278 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
MFNHADDB_01757 1.1e-240 ywoD EGP Major facilitator superfamily
MFNHADDB_01758 6.8e-104 phzA Q Isochorismatase family
MFNHADDB_01759 1.3e-76
MFNHADDB_01760 4.3e-225 amt P Ammonium transporter
MFNHADDB_01761 1.6e-58 nrgB K Belongs to the P(II) protein family
MFNHADDB_01762 1.3e-102 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
MFNHADDB_01763 1.6e-70 ywnJ S VanZ like family
MFNHADDB_01764 2e-115 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
MFNHADDB_01765 4.1e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
MFNHADDB_01766 7.2e-09 ywnC S Family of unknown function (DUF5362)
MFNHADDB_01767 2.9e-70 ywnF S Family of unknown function (DUF5392)
MFNHADDB_01768 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MFNHADDB_01769 1e-142 mta K transcriptional
MFNHADDB_01770 1.7e-58 ywnC S Family of unknown function (DUF5362)
MFNHADDB_01771 5.3e-113 ywnB S NAD(P)H-binding
MFNHADDB_01772 1.7e-64 ywnA K Transcriptional regulator
MFNHADDB_01773 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MFNHADDB_01774 1.9e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
MFNHADDB_01775 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
MFNHADDB_01776 7.3e-09 urtE E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
MFNHADDB_01777 3.8e-11 csbD K CsbD-like
MFNHADDB_01778 3e-84 ywmF S Peptidase M50
MFNHADDB_01779 1.3e-103 S response regulator aspartate phosphatase
MFNHADDB_01780 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MFNHADDB_01781 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MFNHADDB_01783 1.2e-120 ywmD S protein containing a von Willebrand factor type A (vWA) domain
MFNHADDB_01784 5.1e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
MFNHADDB_01785 2.1e-175 spoIID D Stage II sporulation protein D
MFNHADDB_01786 3.6e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MFNHADDB_01787 3.4e-132 ywmB S TATA-box binding
MFNHADDB_01788 1.3e-32 ywzB S membrane
MFNHADDB_01789 9e-86 ywmA
MFNHADDB_01790 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MFNHADDB_01791 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MFNHADDB_01792 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MFNHADDB_01793 4.5e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MFNHADDB_01794 1.6e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MFNHADDB_01795 3.9e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MFNHADDB_01796 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MFNHADDB_01797 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
MFNHADDB_01798 2.5e-62 atpI S ATP synthase
MFNHADDB_01799 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MFNHADDB_01800 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MFNHADDB_01801 3.6e-94 ywlG S Belongs to the UPF0340 family
MFNHADDB_01802 8.3e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
MFNHADDB_01803 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MFNHADDB_01804 1.7e-91 mntP P Probably functions as a manganese efflux pump
MFNHADDB_01805 5.2e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MFNHADDB_01806 4.7e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
MFNHADDB_01807 2.6e-110 spoIIR S stage II sporulation protein R
MFNHADDB_01808 3.7e-55 ywlA S Uncharacterised protein family (UPF0715)
MFNHADDB_01810 2.3e-156 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MFNHADDB_01811 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MFNHADDB_01812 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MFNHADDB_01813 7.1e-90 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MFNHADDB_01814 8.6e-160 ywkB S Membrane transport protein
MFNHADDB_01815 0.0 sfcA 1.1.1.38 C malic enzyme
MFNHADDB_01816 7e-104 tdk 2.7.1.21 F thymidine kinase
MFNHADDB_01817 1.1e-32 rpmE J Binds the 23S rRNA
MFNHADDB_01818 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MFNHADDB_01819 9.5e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
MFNHADDB_01820 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MFNHADDB_01821 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MFNHADDB_01822 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
MFNHADDB_01823 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
MFNHADDB_01824 1.2e-91 ywjG S Domain of unknown function (DUF2529)
MFNHADDB_01825 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MFNHADDB_01826 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MFNHADDB_01827 2.4e-209 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
MFNHADDB_01828 0.0 fadF C COG0247 Fe-S oxidoreductase
MFNHADDB_01829 2.3e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MFNHADDB_01830 3.3e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MFNHADDB_01831 2.7e-42 ywjC
MFNHADDB_01832 3.4e-94 ywjB H RibD C-terminal domain
MFNHADDB_01833 0.0 ywjA V ABC transporter
MFNHADDB_01834 3.2e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MFNHADDB_01835 1.8e-124 narI 1.7.5.1 C nitrate reductase, gamma
MFNHADDB_01836 6.8e-93 narJ 1.7.5.1 C nitrate reductase
MFNHADDB_01837 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
MFNHADDB_01838 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MFNHADDB_01839 2e-85 arfM T cyclic nucleotide binding
MFNHADDB_01840 1.1e-138 ywiC S YwiC-like protein
MFNHADDB_01841 2e-129 fnr K helix_turn_helix, cAMP Regulatory protein
MFNHADDB_01842 1.3e-213 narK P COG2223 Nitrate nitrite transporter
MFNHADDB_01843 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MFNHADDB_01844 4.7e-73 ywiB S protein conserved in bacteria
MFNHADDB_01845 1e-07 S Bacteriocin subtilosin A
MFNHADDB_01846 1.7e-270 C Fe-S oxidoreductases
MFNHADDB_01848 7.4e-132 cbiO V ABC transporter
MFNHADDB_01849 2.7e-233 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
MFNHADDB_01850 2.1e-216 2.7.1.26, 2.7.7.2 L Peptidase, M16
MFNHADDB_01851 8.6e-248 L Peptidase, M16
MFNHADDB_01853 2.5e-245 ywhL CO amine dehydrogenase activity
MFNHADDB_01854 2.5e-205 ywhK CO amine dehydrogenase activity
MFNHADDB_01855 2e-78 S aspartate phosphatase
MFNHADDB_01858 1.7e-20
MFNHADDB_01861 1.4e-57 V ATPases associated with a variety of cellular activities
MFNHADDB_01863 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
MFNHADDB_01864 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MFNHADDB_01865 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MFNHADDB_01866 2e-94 ywhD S YwhD family
MFNHADDB_01867 5.1e-119 ywhC S Peptidase family M50
MFNHADDB_01868 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
MFNHADDB_01869 3.3e-71 ywhA K Transcriptional regulator
MFNHADDB_01870 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MFNHADDB_01872 2.6e-242 mmr U Major Facilitator Superfamily
MFNHADDB_01873 2.8e-79 yffB K Transcriptional regulator
MFNHADDB_01874 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
MFNHADDB_01875 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
MFNHADDB_01876 3.1e-36 ywzC S Belongs to the UPF0741 family
MFNHADDB_01877 3e-110 rsfA_1
MFNHADDB_01878 1.2e-158 ywfM EG EamA-like transporter family
MFNHADDB_01879 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MFNHADDB_01880 2.1e-155 cysL K Transcriptional regulator
MFNHADDB_01881 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
MFNHADDB_01882 1.1e-146 ywfI C May function as heme-dependent peroxidase
MFNHADDB_01883 7.5e-138 IQ Enoyl-(Acyl carrier protein) reductase
MFNHADDB_01884 1.5e-233 ywfG 2.6.1.83 E Aminotransferase class I and II
MFNHADDB_01885 5.6e-209 bacE EGP Major facilitator Superfamily
MFNHADDB_01886 6.1e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MFNHADDB_01887 1.9e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFNHADDB_01888 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MFNHADDB_01889 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MFNHADDB_01890 1.3e-205 ywfA EGP Major facilitator Superfamily
MFNHADDB_01891 3.7e-260 lysP E amino acid
MFNHADDB_01892 0.0 rocB E arginine degradation protein
MFNHADDB_01893 1.7e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MFNHADDB_01894 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MFNHADDB_01895 3.4e-77
MFNHADDB_01896 3.5e-87 spsL 5.1.3.13 M Spore Coat
MFNHADDB_01897 1.5e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MFNHADDB_01898 8.7e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MFNHADDB_01899 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MFNHADDB_01900 5.1e-187 spsG M Spore Coat
MFNHADDB_01901 1.6e-129 spsF M Spore Coat
MFNHADDB_01902 1.6e-213 spsE 2.5.1.56 M acid synthase
MFNHADDB_01903 2e-163 spsD 2.3.1.210 K Spore Coat
MFNHADDB_01904 1e-223 spsC E Belongs to the DegT DnrJ EryC1 family
MFNHADDB_01905 7.5e-266 spsB M Capsule polysaccharide biosynthesis protein
MFNHADDB_01906 1.8e-144 spsA M Spore Coat
MFNHADDB_01907 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MFNHADDB_01908 4.3e-59 ywdK S small membrane protein
MFNHADDB_01909 1.4e-237 ywdJ F Xanthine uracil
MFNHADDB_01910 2.3e-48 ywdI S Family of unknown function (DUF5327)
MFNHADDB_01911 4e-259 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
MFNHADDB_01912 1.1e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MFNHADDB_01913 5.5e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
MFNHADDB_01914 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MFNHADDB_01915 2e-28 ywdA
MFNHADDB_01916 7.5e-293 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
MFNHADDB_01917 7.3e-253 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MFNHADDB_01918 5.7e-138 focA P Formate/nitrite transporter
MFNHADDB_01919 7e-150 sacT K transcriptional antiterminator
MFNHADDB_01921 0.0 vpr O Belongs to the peptidase S8 family
MFNHADDB_01922 9.5e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MFNHADDB_01923 2.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
MFNHADDB_01924 8.6e-202 rodA D Belongs to the SEDS family
MFNHADDB_01925 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
MFNHADDB_01926 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MFNHADDB_01927 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MFNHADDB_01928 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MFNHADDB_01929 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MFNHADDB_01930 1e-35 ywzA S membrane
MFNHADDB_01931 7.5e-299 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MFNHADDB_01932 1.4e-228 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MFNHADDB_01933 1.4e-58 gtcA S GtrA-like protein
MFNHADDB_01934 1.1e-121 ywcC K transcriptional regulator
MFNHADDB_01936 6.4e-48 ywcB S Protein of unknown function, DUF485
MFNHADDB_01937 3.1e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MFNHADDB_01938 4.6e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MFNHADDB_01939 3.2e-223 ywbN P Dyp-type peroxidase family protein
MFNHADDB_01940 4.2e-185 ycdO P periplasmic lipoprotein involved in iron transport
MFNHADDB_01941 6.5e-252 P COG0672 High-affinity Fe2 Pb2 permease
MFNHADDB_01942 1.4e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MFNHADDB_01943 1.4e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MFNHADDB_01944 4.3e-153 ywbI K Transcriptional regulator
MFNHADDB_01945 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MFNHADDB_01946 2.3e-111 ywbG M effector of murein hydrolase
MFNHADDB_01947 8.1e-208 ywbF EGP Major facilitator Superfamily
MFNHADDB_01948 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
MFNHADDB_01949 2e-219 ywbD 2.1.1.191 J Methyltransferase
MFNHADDB_01950 4.9e-66 ywbC 4.4.1.5 E glyoxalase
MFNHADDB_01951 7.1e-245 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFNHADDB_01952 7.5e-272 epr 3.4.21.62 O Belongs to the peptidase S8 family
MFNHADDB_01953 2e-242 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MFNHADDB_01954 1.2e-152 sacY K transcriptional antiterminator
MFNHADDB_01955 1e-167 gspA M General stress
MFNHADDB_01956 1.5e-124 ywaF S Integral membrane protein
MFNHADDB_01957 4e-87 ywaE K Transcriptional regulator
MFNHADDB_01958 2.4e-231 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MFNHADDB_01959 5.7e-250 ywaD 3.4.11.10, 3.4.11.6 S PA domain
MFNHADDB_01960 1.4e-92 K Helix-turn-helix XRE-family like proteins
MFNHADDB_01961 1.2e-48 4.1.1.44 S Carboxymuconolactone decarboxylase family
MFNHADDB_01962 1.3e-35 ynfM EGP Major facilitator Superfamily
MFNHADDB_01963 3.3e-82 ynfM EGP Major facilitator Superfamily
MFNHADDB_01964 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
MFNHADDB_01965 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
MFNHADDB_01966 6.7e-292 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFNHADDB_01967 1.4e-231 dltB M membrane protein involved in D-alanine export
MFNHADDB_01968 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFNHADDB_01969 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MFNHADDB_01970 1.2e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
MFNHADDB_01971 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MFNHADDB_01972 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MFNHADDB_01973 1.9e-37 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
MFNHADDB_01974 2.8e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFNHADDB_01975 5.2e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
MFNHADDB_01976 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
MFNHADDB_01977 1.1e-19 yxzF
MFNHADDB_01978 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MFNHADDB_01979 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MFNHADDB_01980 2.6e-44 yxlH EGP Major facilitator Superfamily
MFNHADDB_01981 2.9e-157 yxlH EGP Major facilitator Superfamily
MFNHADDB_01982 1.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MFNHADDB_01983 7e-164 yxlF V ABC transporter, ATP-binding protein
MFNHADDB_01984 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
MFNHADDB_01985 1.4e-30
MFNHADDB_01986 3.9e-48 yxlC S Family of unknown function (DUF5345)
MFNHADDB_01987 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
MFNHADDB_01988 1.9e-253 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
MFNHADDB_01989 4.8e-159 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MFNHADDB_01990 0.0 cydD V ATP-binding protein
MFNHADDB_01991 0.0 cydD V ATP-binding
MFNHADDB_01992 8.4e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
MFNHADDB_01993 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
MFNHADDB_01994 2.1e-228 cimH C COG3493 Na citrate symporter
MFNHADDB_01995 1.3e-307 3.4.24.84 O Peptidase family M48
MFNHADDB_01997 1.1e-155 yxkH G Polysaccharide deacetylase
MFNHADDB_01998 2.2e-204 msmK P Belongs to the ABC transporter superfamily
MFNHADDB_01999 2e-163 lrp QT PucR C-terminal helix-turn-helix domain
MFNHADDB_02000 4.8e-271 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MFNHADDB_02001 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MFNHADDB_02002 1.4e-73 yxkC S Domain of unknown function (DUF4352)
MFNHADDB_02003 6.7e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MFNHADDB_02004 1.3e-93 yxkA S Phosphatidylethanolamine-binding protein
MFNHADDB_02005 2.1e-165 yxjO K LysR substrate binding domain
MFNHADDB_02006 1e-76 S Protein of unknown function (DUF1453)
MFNHADDB_02007 8.3e-192 yxjM T Signal transduction histidine kinase
MFNHADDB_02008 7.1e-113 K helix_turn_helix, Lux Regulon
MFNHADDB_02009 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MFNHADDB_02012 7.1e-86 yxjI S LURP-one-related
MFNHADDB_02013 6.7e-220 yxjG 2.1.1.14 E Methionine synthase
MFNHADDB_02014 8.2e-218 yxjG 2.1.1.14 E Methionine synthase
MFNHADDB_02015 2.4e-136 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MFNHADDB_02016 1.2e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MFNHADDB_02017 6.9e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MFNHADDB_02018 1.3e-249 yxjC EG COG2610 H gluconate symporter and related permeases
MFNHADDB_02019 1.6e-157 rlmA 2.1.1.187 Q Methyltransferase domain
MFNHADDB_02020 4.1e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MFNHADDB_02021 4e-103 T Domain of unknown function (DUF4163)
MFNHADDB_02022 3e-47 yxiS
MFNHADDB_02023 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
MFNHADDB_02024 6.6e-224 citH C Citrate transporter
MFNHADDB_02025 1.1e-143 exoK GH16 M licheninase activity
MFNHADDB_02026 8.3e-151 licT K transcriptional antiterminator
MFNHADDB_02027 2.4e-111
MFNHADDB_02028 3.9e-232 yxiO S COG2270 Permeases of the major facilitator superfamily
MFNHADDB_02029 3.9e-265 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MFNHADDB_02030 2.8e-213 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
MFNHADDB_02033 1.4e-32 yxiJ S YxiJ-like protein
MFNHADDB_02034 4.6e-93 yxiI S Protein of unknown function (DUF2716)
MFNHADDB_02035 4.8e-163 yxxF EG EamA-like transporter family
MFNHADDB_02036 1.1e-72 yxiE T Belongs to the universal stress protein A family
MFNHADDB_02037 8.1e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MFNHADDB_02038 1.5e-309 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MFNHADDB_02040 1.4e-77 S SMI1 / KNR4 family
MFNHADDB_02041 3.2e-298 S nuclease activity
MFNHADDB_02042 2.3e-38 yxiC S Family of unknown function (DUF5344)
MFNHADDB_02043 4.2e-21 S Domain of unknown function (DUF5082)
MFNHADDB_02044 1.6e-263 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
MFNHADDB_02046 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MFNHADDB_02047 2.2e-282 hutH 4.3.1.3 E Histidine ammonia-lyase
MFNHADDB_02048 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MFNHADDB_02049 1.3e-235 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
MFNHADDB_02050 1.7e-179 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MFNHADDB_02051 4.4e-250 lysP E amino acid
MFNHADDB_02052 7.9e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
MFNHADDB_02053 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MFNHADDB_02054 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MFNHADDB_02055 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MFNHADDB_02056 2e-152 yxxB S Domain of Unknown Function (DUF1206)
MFNHADDB_02057 6.6e-196 eutH E Ethanolamine utilisation protein, EutH
MFNHADDB_02058 6.2e-249 yxeQ S MmgE/PrpD family
MFNHADDB_02059 5.2e-212 yxeP 3.5.1.47 E hydrolase activity
MFNHADDB_02060 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
MFNHADDB_02061 2.7e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
MFNHADDB_02062 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
MFNHADDB_02063 1.6e-93 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MFNHADDB_02064 2.8e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MFNHADDB_02066 1.3e-187 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
MFNHADDB_02067 1.8e-150 yidA S hydrolases of the HAD superfamily
MFNHADDB_02070 1.3e-20 yxeE
MFNHADDB_02071 5.6e-16 yxeD
MFNHADDB_02072 1.4e-68
MFNHADDB_02073 5.1e-176 fhuD P ABC transporter
MFNHADDB_02074 1.5e-58 yxeA S Protein of unknown function (DUF1093)
MFNHADDB_02075 0.0 yxdM V ABC transporter (permease)
MFNHADDB_02076 2.7e-140 yxdL V ABC transporter, ATP-binding protein
MFNHADDB_02077 2e-180 T PhoQ Sensor
MFNHADDB_02078 2.7e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFNHADDB_02079 1.2e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MFNHADDB_02080 5.6e-139 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MFNHADDB_02081 8.6e-167 iolH G Xylose isomerase-like TIM barrel
MFNHADDB_02082 1.8e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MFNHADDB_02083 9.6e-234 iolF EGP Major facilitator Superfamily
MFNHADDB_02084 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MFNHADDB_02085 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MFNHADDB_02086 7.1e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MFNHADDB_02087 1.1e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MFNHADDB_02088 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MFNHADDB_02089 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
MFNHADDB_02090 8.3e-176 iolS C Aldo keto reductase
MFNHADDB_02092 8.3e-48 yxcD S Protein of unknown function (DUF2653)
MFNHADDB_02093 2.8e-244 csbC EGP Major facilitator Superfamily
MFNHADDB_02094 0.0 htpG O Molecular chaperone. Has ATPase activity
MFNHADDB_02096 2.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
MFNHADDB_02097 9.1e-209 yxbF K Bacterial regulatory proteins, tetR family
MFNHADDB_02098 5.2e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
MFNHADDB_02099 3.1e-30 yxaI S membrane protein domain
MFNHADDB_02100 9.9e-92 S PQQ-like domain
MFNHADDB_02101 3e-64 S Family of unknown function (DUF5391)
MFNHADDB_02102 1.4e-75 yxaI S membrane protein domain
MFNHADDB_02103 1.5e-222 P Protein of unknown function (DUF418)
MFNHADDB_02104 2.7e-196 yxaG 1.13.11.24 S AraC-like ligand binding domain
MFNHADDB_02105 1.6e-100 yxaF K Transcriptional regulator
MFNHADDB_02106 6.1e-199 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MFNHADDB_02107 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
MFNHADDB_02108 4.9e-48 S LrgA family
MFNHADDB_02109 5e-117 yxaC M effector of murein hydrolase
MFNHADDB_02110 3.7e-193 yxaB GM Polysaccharide pyruvyl transferase
MFNHADDB_02111 5.6e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MFNHADDB_02112 2.1e-126 gntR K transcriptional
MFNHADDB_02113 1.1e-302 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
MFNHADDB_02114 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
MFNHADDB_02115 4.3e-269 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MFNHADDB_02116 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
MFNHADDB_02117 1.1e-286 ahpF O Alkyl hydroperoxide reductase
MFNHADDB_02118 7.3e-189 wgaE S Polysaccharide pyruvyl transferase
MFNHADDB_02119 3e-289 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MFNHADDB_02120 3.7e-32 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
MFNHADDB_02121 3.8e-128 yydK K Transcriptional regulator
MFNHADDB_02122 7.6e-13
MFNHADDB_02123 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
MFNHADDB_02124 3.4e-73 cca 2.7.7.19, 2.7.7.72 J COG0617 tRNA nucleotidyltransferase poly(A) polymerase
MFNHADDB_02125 7.6e-210 S Protein of unknown function DUF262
MFNHADDB_02126 0.0 2.1.1.72, 3.1.21.4 L DEAD-like helicases superfamily
MFNHADDB_02127 1e-99 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
MFNHADDB_02128 1.6e-134 spoIVCA L Recombinase zinc beta ribbon domain
MFNHADDB_02129 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MFNHADDB_02130 1.1e-09 S YyzF-like protein
MFNHADDB_02131 1.8e-69
MFNHADDB_02132 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MFNHADDB_02134 2.6e-31 yycQ S Protein of unknown function (DUF2651)
MFNHADDB_02135 1.1e-206 yycP
MFNHADDB_02136 1.1e-130 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MFNHADDB_02137 8.4e-84 yycN 2.3.1.128 K Acetyltransferase
MFNHADDB_02138 1.5e-187 S aspartate phosphatase
MFNHADDB_02140 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
MFNHADDB_02141 1.3e-260 rocE E amino acid
MFNHADDB_02142 1.3e-232 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
MFNHADDB_02143 6.4e-257 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MFNHADDB_02144 5.7e-171 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
MFNHADDB_02145 1.5e-94 K PFAM response regulator receiver
MFNHADDB_02146 1.4e-74 S Peptidase propeptide and YPEB domain
MFNHADDB_02147 9.4e-25 S Peptidase propeptide and YPEB domain
MFNHADDB_02148 8.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MFNHADDB_02149 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MFNHADDB_02150 1.1e-153 yycI S protein conserved in bacteria
MFNHADDB_02151 1.3e-257 yycH S protein conserved in bacteria
MFNHADDB_02152 0.0 vicK 2.7.13.3 T Histidine kinase
MFNHADDB_02153 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFNHADDB_02158 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MFNHADDB_02159 5.2e-77 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MFNHADDB_02160 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MFNHADDB_02161 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
MFNHADDB_02163 1.9e-15 yycC K YycC-like protein
MFNHADDB_02164 8.4e-221 yeaN P COG2807 Cyanate permease
MFNHADDB_02165 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MFNHADDB_02166 2.2e-73 rplI J binds to the 23S rRNA
MFNHADDB_02167 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MFNHADDB_02168 8.3e-160 yybS S membrane
MFNHADDB_02170 3.3e-83 cotF M Spore coat protein
MFNHADDB_02171 7.5e-67 ydeP3 K Transcriptional regulator
MFNHADDB_02172 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
MFNHADDB_02173 1.5e-58
MFNHADDB_02175 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
MFNHADDB_02176 9.7e-111 K TipAS antibiotic-recognition domain
MFNHADDB_02177 4.8e-124
MFNHADDB_02178 6.5e-66 yybH S SnoaL-like domain
MFNHADDB_02179 3e-124 yybG S Pentapeptide repeat-containing protein
MFNHADDB_02180 1.5e-217 ynfM EGP Major facilitator Superfamily
MFNHADDB_02181 1.7e-162 yybE K Transcriptional regulator
MFNHADDB_02182 7.7e-79 yjcF S Acetyltransferase (GNAT) domain
MFNHADDB_02183 2.3e-73 yybC
MFNHADDB_02184 2.1e-125 S Metallo-beta-lactamase superfamily
MFNHADDB_02185 5.6e-77 yybA 2.3.1.57 K transcriptional
MFNHADDB_02186 2.9e-70 yjcF S Acetyltransferase (GNAT) domain
MFNHADDB_02187 3.2e-96 yyaS S Membrane
MFNHADDB_02188 2.1e-91 yyaR K Acetyltransferase (GNAT) domain
MFNHADDB_02189 3.5e-66 yyaQ S YjbR
MFNHADDB_02190 1.4e-104 yyaP 1.5.1.3 H RibD C-terminal domain
MFNHADDB_02191 1.1e-243 tetL EGP Major facilitator Superfamily
MFNHADDB_02193 7.5e-10 S Putative amidase domain
MFNHADDB_02194 5.1e-61 yyaN K MerR HTH family regulatory protein
MFNHADDB_02195 4.4e-161 yyaM EG EamA-like transporter family
MFNHADDB_02196 3.4e-21 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
MFNHADDB_02197 2.5e-67 yrhP E LysE type translocator
MFNHADDB_02198 5.7e-24 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
MFNHADDB_02199 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
MFNHADDB_02200 8e-168 yyaK S CAAX protease self-immunity
MFNHADDB_02201 6.1e-244 EGP Major facilitator superfamily
MFNHADDB_02202 8.1e-94 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
MFNHADDB_02203 8.9e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MFNHADDB_02204 6.8e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
MFNHADDB_02205 1.7e-142 xth 3.1.11.2 L exodeoxyribonuclease III
MFNHADDB_02206 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MFNHADDB_02207 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MFNHADDB_02208 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
MFNHADDB_02209 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MFNHADDB_02210 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MFNHADDB_02211 2.3e-33 yyzM S protein conserved in bacteria
MFNHADDB_02212 8.1e-177 yyaD S Membrane
MFNHADDB_02213 2.1e-111 yyaC S Sporulation protein YyaC
MFNHADDB_02214 3.9e-148 spo0J K Belongs to the ParB family
MFNHADDB_02215 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
MFNHADDB_02216 1.1e-72 S Bacterial PH domain
MFNHADDB_02217 5.5e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MFNHADDB_02218 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MFNHADDB_02219 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MFNHADDB_02220 1.1e-248 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MFNHADDB_02221 6.5e-108 jag S single-stranded nucleic acid binding R3H
MFNHADDB_02222 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MFNHADDB_02223 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MFNHADDB_02224 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MFNHADDB_02225 5.2e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MFNHADDB_02226 2.4e-33 yaaA S S4 domain
MFNHADDB_02227 5.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MFNHADDB_02228 1.8e-37 yaaB S Domain of unknown function (DUF370)
MFNHADDB_02229 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MFNHADDB_02230 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MFNHADDB_02231 7.2e-70 Q Collagen triple helix repeat (20 copies)
MFNHADDB_02232 1e-31
MFNHADDB_02233 5e-10
MFNHADDB_02236 4.7e-35 S Terminase
MFNHADDB_02237 1.8e-79 L phage terminase small subunit
MFNHADDB_02238 4.4e-48 V HNH endonuclease
MFNHADDB_02243 3.1e-18 N HicA toxin of bacterial toxin-antitoxin,
MFNHADDB_02244 5.4e-66 S regulation of transcription, DNA-dependent
MFNHADDB_02245 2.7e-26 S FRG
MFNHADDB_02246 1.5e-50 wecC 1.1.1.336 M ArpU family transcriptional regulator
MFNHADDB_02249 1.6e-21
MFNHADDB_02250 2.9e-102 dnaB 3.6.4.12 L replicative DNA helicase
MFNHADDB_02251 2.3e-38 L Arm DNA-binding domain
MFNHADDB_02252 3.5e-260 glnA 6.3.1.2 E glutamine synthetase
MFNHADDB_02253 1.1e-68 glnR K transcriptional
MFNHADDB_02254 4.8e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MFNHADDB_02255 2.1e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MFNHADDB_02256 3.9e-176 spoVK O stage V sporulation protein K
MFNHADDB_02257 7.5e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MFNHADDB_02258 2e-109 ymaB
MFNHADDB_02259 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MFNHADDB_02260 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MFNHADDB_02261 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
MFNHADDB_02262 4.5e-22 ymzA
MFNHADDB_02263 8.2e-23
MFNHADDB_02264 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MFNHADDB_02265 3.5e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MFNHADDB_02266 2.1e-46 ymaF S YmaF family
MFNHADDB_02268 4.9e-51 ebrA P Small Multidrug Resistance protein
MFNHADDB_02269 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
MFNHADDB_02270 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
MFNHADDB_02271 2.1e-126 ymaC S Replication protein
MFNHADDB_02272 1.9e-07 K Transcriptional regulator
MFNHADDB_02273 1.5e-250 aprX O Belongs to the peptidase S8 family
MFNHADDB_02274 4.4e-160 ymaE S Metallo-beta-lactamase superfamily
MFNHADDB_02275 2e-61 ymzB
MFNHADDB_02276 5.3e-231 cypA C Cytochrome P450
MFNHADDB_02277 0.0 pks13 HQ Beta-ketoacyl synthase
MFNHADDB_02278 0.0 dhbF IQ polyketide synthase
MFNHADDB_02279 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
MFNHADDB_02280 0.0 pfaA Q Polyketide synthase of type I
MFNHADDB_02281 0.0 rhiB IQ polyketide synthase
MFNHADDB_02282 7.5e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
MFNHADDB_02283 1.3e-142 pksH 4.2.1.18 I enoyl-CoA hydratase
MFNHADDB_02284 1.3e-245 pksG 2.3.3.10 I synthase
MFNHADDB_02285 1.3e-237 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MFNHADDB_02286 1.4e-37 acpK IQ Phosphopantetheine attachment site
MFNHADDB_02287 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MFNHADDB_02288 9.6e-183 pksD Q Acyl transferase domain
MFNHADDB_02290 2.2e-162 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MFNHADDB_02291 3.7e-125 pksB 3.1.2.6 S Polyketide biosynthesis
MFNHADDB_02292 2.9e-108 pksA K Transcriptional regulator
MFNHADDB_02293 7.9e-97 ymcC S Membrane
MFNHADDB_02295 5.1e-70 S Regulatory protein YrvL
MFNHADDB_02296 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MFNHADDB_02297 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MFNHADDB_02298 2.2e-88 cotE S Spore coat protein
MFNHADDB_02299 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
MFNHADDB_02300 8.5e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MFNHADDB_02301 7.2e-217 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MFNHADDB_02302 3e-198 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MFNHADDB_02303 1.2e-36 spoVS S Stage V sporulation protein S
MFNHADDB_02304 7.1e-152 ymdB S protein conserved in bacteria
MFNHADDB_02305 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
MFNHADDB_02306 2.6e-214 pbpX V Beta-lactamase
MFNHADDB_02307 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MFNHADDB_02308 9.6e-236 cinA 3.5.1.42 S Belongs to the CinA family
MFNHADDB_02309 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MFNHADDB_02310 1.9e-124 ymfM S protein conserved in bacteria
MFNHADDB_02311 2.7e-143 ymfK S Protein of unknown function (DUF3388)
MFNHADDB_02312 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
MFNHADDB_02313 7.8e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MFNHADDB_02314 4.1e-242 ymfH S zinc protease
MFNHADDB_02315 2e-233 ymfF S Peptidase M16
MFNHADDB_02316 3.8e-205 ymfD EGP Major facilitator Superfamily
MFNHADDB_02317 1.4e-133 ymfC K Transcriptional regulator
MFNHADDB_02318 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MFNHADDB_02319 4.4e-32 S YlzJ-like protein
MFNHADDB_02320 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
MFNHADDB_02321 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MFNHADDB_02322 4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MFNHADDB_02323 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MFNHADDB_02324 3.2e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MFNHADDB_02325 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MFNHADDB_02326 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
MFNHADDB_02327 2.6e-42 ymxH S YlmC YmxH family
MFNHADDB_02328 4.4e-233 pepR S Belongs to the peptidase M16 family
MFNHADDB_02329 1.2e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
MFNHADDB_02330 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MFNHADDB_02331 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MFNHADDB_02332 3e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MFNHADDB_02333 1.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MFNHADDB_02334 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MFNHADDB_02335 3.9e-44 ylxP S protein conserved in bacteria
MFNHADDB_02336 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MFNHADDB_02337 3.1e-47 ylxQ J ribosomal protein
MFNHADDB_02338 7.5e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
MFNHADDB_02339 1.1e-203 nusA K Participates in both transcription termination and antitermination
MFNHADDB_02340 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
MFNHADDB_02341 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MFNHADDB_02342 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MFNHADDB_02343 7.7e-233 rasP M zinc metalloprotease
MFNHADDB_02344 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MFNHADDB_02345 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
MFNHADDB_02346 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MFNHADDB_02347 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MFNHADDB_02348 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MFNHADDB_02349 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MFNHADDB_02350 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
MFNHADDB_02351 3.1e-76 ylxL
MFNHADDB_02352 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MFNHADDB_02353 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MFNHADDB_02354 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MFNHADDB_02355 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
MFNHADDB_02356 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
MFNHADDB_02357 7.5e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MFNHADDB_02358 7.5e-158 flhG D Belongs to the ParA family
MFNHADDB_02359 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
MFNHADDB_02360 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MFNHADDB_02361 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MFNHADDB_02362 3.6e-132 fliR N Flagellar biosynthetic protein FliR
MFNHADDB_02363 2.2e-36 fliQ N Role in flagellar biosynthesis
MFNHADDB_02364 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
MFNHADDB_02365 2.1e-96 fliZ N Flagellar biosynthesis protein, FliO
MFNHADDB_02366 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
MFNHADDB_02367 5.9e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MFNHADDB_02368 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MFNHADDB_02369 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
MFNHADDB_02370 8.2e-140 flgG N Flagellar basal body rod
MFNHADDB_02371 1.7e-72 flgD N Flagellar basal body rod modification protein
MFNHADDB_02372 4.4e-216 fliK N Flagellar hook-length control protein
MFNHADDB_02373 7.7e-37 ylxF S MgtE intracellular N domain
MFNHADDB_02374 1.5e-69 fliJ N Flagellar biosynthesis chaperone
MFNHADDB_02375 7.2e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MFNHADDB_02376 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
MFNHADDB_02377 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MFNHADDB_02378 2.4e-255 fliF N The M ring may be actively involved in energy transduction
MFNHADDB_02379 1.9e-31 fliE N Flagellar hook-basal body
MFNHADDB_02380 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
MFNHADDB_02381 6.8e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MFNHADDB_02382 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MFNHADDB_02383 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MFNHADDB_02384 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MFNHADDB_02385 2.5e-169 xerC L tyrosine recombinase XerC
MFNHADDB_02386 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MFNHADDB_02387 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MFNHADDB_02388 5e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
MFNHADDB_02389 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MFNHADDB_02390 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MFNHADDB_02391 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
MFNHADDB_02392 1e-288 ylqG
MFNHADDB_02393 6.9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MFNHADDB_02394 1.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MFNHADDB_02395 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MFNHADDB_02396 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MFNHADDB_02397 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MFNHADDB_02398 6.3e-61 ylqD S YlqD protein
MFNHADDB_02399 4.5e-36 ylqC S Belongs to the UPF0109 family
MFNHADDB_02400 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MFNHADDB_02401 6e-236 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MFNHADDB_02402 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MFNHADDB_02403 2.9e-87
MFNHADDB_02404 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MFNHADDB_02405 0.0 smc D Required for chromosome condensation and partitioning
MFNHADDB_02406 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MFNHADDB_02407 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MFNHADDB_02408 6.1e-129 IQ reductase
MFNHADDB_02409 2.9e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MFNHADDB_02410 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MFNHADDB_02411 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MFNHADDB_02412 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MFNHADDB_02413 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
MFNHADDB_02414 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
MFNHADDB_02415 4.3e-300 yloV S kinase related to dihydroxyacetone kinase
MFNHADDB_02416 5.5e-59 asp S protein conserved in bacteria
MFNHADDB_02417 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MFNHADDB_02418 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
MFNHADDB_02419 8e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MFNHADDB_02420 3.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MFNHADDB_02421 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
MFNHADDB_02422 1.6e-140 stp 3.1.3.16 T phosphatase
MFNHADDB_02423 1.4e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MFNHADDB_02424 8.4e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MFNHADDB_02425 1.1e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MFNHADDB_02426 1.3e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MFNHADDB_02427 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MFNHADDB_02428 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MFNHADDB_02429 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MFNHADDB_02430 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MFNHADDB_02431 1.5e-40 ylzA S Belongs to the UPF0296 family
MFNHADDB_02432 2.4e-156 yloC S stress-induced protein
MFNHADDB_02433 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
MFNHADDB_02434 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
MFNHADDB_02435 1.1e-81 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
MFNHADDB_02436 4.9e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
MFNHADDB_02437 4.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MFNHADDB_02438 6.2e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
MFNHADDB_02439 5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MFNHADDB_02440 5.4e-179 cysP P phosphate transporter
MFNHADDB_02441 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MFNHADDB_02443 5.6e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MFNHADDB_02444 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MFNHADDB_02445 5.1e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MFNHADDB_02446 1.4e-144 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MFNHADDB_02447 0.0 carB 6.3.5.5 F Belongs to the CarB family
MFNHADDB_02448 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MFNHADDB_02449 4.1e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MFNHADDB_02450 2e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MFNHADDB_02451 7.6e-231 pyrP F Xanthine uracil
MFNHADDB_02452 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MFNHADDB_02453 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MFNHADDB_02454 4e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MFNHADDB_02455 2.2e-63 dksA T COG1734 DnaK suppressor protein
MFNHADDB_02456 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MFNHADDB_02457 2.6e-67 divIVA D Cell division initiation protein
MFNHADDB_02458 6.7e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
MFNHADDB_02459 1.6e-39 yggT S membrane
MFNHADDB_02460 5.1e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MFNHADDB_02461 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MFNHADDB_02462 6.6e-156 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
MFNHADDB_02463 2.4e-37 ylmC S sporulation protein
MFNHADDB_02464 4e-253 argE 3.5.1.16 E Acetylornithine deacetylase
MFNHADDB_02465 3.4e-146 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MFNHADDB_02466 6.2e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MFNHADDB_02467 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MFNHADDB_02468 1.2e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MFNHADDB_02470 0.0 bpr O COG1404 Subtilisin-like serine proteases
MFNHADDB_02471 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MFNHADDB_02472 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MFNHADDB_02473 6.2e-58 sbp S small basic protein
MFNHADDB_02474 1.8e-91 ylxX S protein conserved in bacteria
MFNHADDB_02475 4.1e-103 ylxW S protein conserved in bacteria
MFNHADDB_02476 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MFNHADDB_02477 5.3e-167 murB 1.3.1.98 M cell wall formation
MFNHADDB_02478 5.7e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MFNHADDB_02479 5.7e-186 spoVE D Belongs to the SEDS family
MFNHADDB_02480 1.7e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MFNHADDB_02481 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MFNHADDB_02482 8.9e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MFNHADDB_02483 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
MFNHADDB_02484 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MFNHADDB_02485 3.7e-44 ftsL D Essential cell division protein
MFNHADDB_02486 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MFNHADDB_02487 2.9e-78 mraZ K Belongs to the MraZ family
MFNHADDB_02488 1.8e-306 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MFNHADDB_02489 1.6e-168 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MFNHADDB_02490 1.5e-88 ylbP K n-acetyltransferase
MFNHADDB_02491 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MFNHADDB_02492 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MFNHADDB_02493 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
MFNHADDB_02495 6e-230 ylbM S Belongs to the UPF0348 family
MFNHADDB_02496 2e-186 ylbL T Belongs to the peptidase S16 family
MFNHADDB_02497 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
MFNHADDB_02498 1.5e-220 ylbJ S Sporulation integral membrane protein YlbJ
MFNHADDB_02499 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MFNHADDB_02500 1.6e-97 rsmD 2.1.1.171 L Methyltransferase
MFNHADDB_02501 2.2e-38 ylbG S UPF0298 protein
MFNHADDB_02502 1.8e-75 ylbF S Belongs to the UPF0342 family
MFNHADDB_02503 6.7e-37 ylbE S YlbE-like protein
MFNHADDB_02504 4.1e-63 ylbD S Putative coat protein
MFNHADDB_02505 4.3e-200 ylbC S protein with SCP PR1 domains
MFNHADDB_02506 4.4e-74 ylbB T COG0517 FOG CBS domain
MFNHADDB_02507 7e-62 ylbA S YugN-like family
MFNHADDB_02508 3e-167 ctaG S cytochrome c oxidase
MFNHADDB_02509 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MFNHADDB_02510 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MFNHADDB_02511 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MFNHADDB_02512 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MFNHADDB_02513 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MFNHADDB_02514 4.2e-164 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MFNHADDB_02515 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MFNHADDB_02516 1.2e-211 ftsW D Belongs to the SEDS family
MFNHADDB_02517 2.5e-43 ylaN S Belongs to the UPF0358 family
MFNHADDB_02518 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
MFNHADDB_02519 1e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MFNHADDB_02520 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
MFNHADDB_02521 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MFNHADDB_02522 2.5e-32 ylaI S protein conserved in bacteria
MFNHADDB_02523 4.2e-47 ylaH S YlaH-like protein
MFNHADDB_02524 0.0 typA T GTP-binding protein TypA
MFNHADDB_02525 8.2e-22 S Family of unknown function (DUF5325)
MFNHADDB_02526 1.8e-38 ylaE
MFNHADDB_02527 2.7e-11 sigC S Putative zinc-finger
MFNHADDB_02528 9.6e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
MFNHADDB_02529 2.7e-42 ylaB
MFNHADDB_02530 0.0 ylaA
MFNHADDB_02531 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
MFNHADDB_02532 1e-170 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MFNHADDB_02533 2e-77 ykzC S Acetyltransferase (GNAT) family
MFNHADDB_02534 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
MFNHADDB_02535 7.1e-26 ykzI
MFNHADDB_02536 6.6e-116 yktB S Belongs to the UPF0637 family
MFNHADDB_02537 1.6e-42 yktA S Belongs to the UPF0223 family
MFNHADDB_02538 2.9e-276 speA 4.1.1.19 E Arginine
MFNHADDB_02539 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
MFNHADDB_02540 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MFNHADDB_02541 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MFNHADDB_02542 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MFNHADDB_02543 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MFNHADDB_02544 3e-108 recN L Putative cell-wall binding lipoprotein
MFNHADDB_02546 1.5e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MFNHADDB_02547 1.6e-146 ykrA S hydrolases of the HAD superfamily
MFNHADDB_02548 8.2e-31 ykzG S Belongs to the UPF0356 family
MFNHADDB_02549 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MFNHADDB_02550 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MFNHADDB_02551 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
MFNHADDB_02552 3.2e-155 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
MFNHADDB_02553 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
MFNHADDB_02554 1.5e-43 abrB K of stationary sporulation gene expression
MFNHADDB_02555 2.9e-182 mreB D Rod-share determining protein MreBH
MFNHADDB_02556 1.1e-12 S Uncharacterized protein YkpC
MFNHADDB_02557 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
MFNHADDB_02558 4.8e-168 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MFNHADDB_02559 2.2e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MFNHADDB_02560 8.1e-39 ykoA
MFNHADDB_02561 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MFNHADDB_02562 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MFNHADDB_02563 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
MFNHADDB_02564 3.1e-136 fruR K Transcriptional regulator
MFNHADDB_02565 2.1e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
MFNHADDB_02566 2.7e-123 macB V ABC transporter, ATP-binding protein
MFNHADDB_02567 1.1e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MFNHADDB_02568 8.5e-117 yknW S Yip1 domain
MFNHADDB_02569 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
MFNHADDB_02570 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
MFNHADDB_02571 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MFNHADDB_02572 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
MFNHADDB_02573 1.3e-93 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
MFNHADDB_02574 4.9e-243 moeA 2.10.1.1 H molybdopterin
MFNHADDB_02575 2.9e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MFNHADDB_02576 3.3e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MFNHADDB_02577 8.4e-147 yknT
MFNHADDB_02578 5.8e-95 rok K Repressor of ComK
MFNHADDB_02579 6.3e-81 ykuV CO thiol-disulfide
MFNHADDB_02580 3.9e-101 ykuU O Alkyl hydroperoxide reductase
MFNHADDB_02581 8.8e-142 ykuT M Mechanosensitive ion channel
MFNHADDB_02582 9e-37 ykuS S Belongs to the UPF0180 family
MFNHADDB_02583 2.4e-214 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MFNHADDB_02584 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MFNHADDB_02585 1.3e-78 fld C Flavodoxin
MFNHADDB_02586 1.6e-176 ykuO
MFNHADDB_02587 6.5e-84 fld C Flavodoxin domain
MFNHADDB_02588 3.5e-168 ccpC K Transcriptional regulator
MFNHADDB_02589 1.6e-76 ykuL S CBS domain
MFNHADDB_02590 3.9e-27 ykzF S Antirepressor AbbA
MFNHADDB_02591 4.4e-94 ykuK S Ribonuclease H-like
MFNHADDB_02592 3.9e-37 ykuJ S protein conserved in bacteria
MFNHADDB_02593 4.4e-233 ykuI T Diguanylate phosphodiesterase
MFNHADDB_02594 1.2e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFNHADDB_02595 2.3e-164 ykuE S Metallophosphoesterase
MFNHADDB_02596 1.8e-87 ykuD S protein conserved in bacteria
MFNHADDB_02597 8.1e-238 ykuC EGP Major facilitator Superfamily
MFNHADDB_02598 1.7e-84 ykyB S YkyB-like protein
MFNHADDB_02599 1.4e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
MFNHADDB_02600 2.2e-15
MFNHADDB_02601 6.3e-221 patA 2.6.1.1 E Aminotransferase
MFNHADDB_02602 0.0 pilS 2.7.13.3 T Histidine kinase
MFNHADDB_02603 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
MFNHADDB_02604 5.7e-122 ykwD J protein with SCP PR1 domains
MFNHADDB_02605 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MFNHADDB_02606 8.2e-258 mcpC NT chemotaxis protein
MFNHADDB_02607 1.1e-129 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MFNHADDB_02608 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
MFNHADDB_02609 7.2e-39 splA S Transcriptional regulator
MFNHADDB_02610 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MFNHADDB_02611 2.1e-39 ptsH G phosphocarrier protein HPr
MFNHADDB_02612 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MFNHADDB_02613 7.6e-128 glcT K antiterminator
MFNHADDB_02615 9.2e-178 ykvZ 5.1.1.1 K Transcriptional regulator
MFNHADDB_02616 1.1e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MFNHADDB_02617 1e-09
MFNHADDB_02618 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MFNHADDB_02619 3.5e-88 stoA CO thiol-disulfide
MFNHADDB_02620 2.9e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MFNHADDB_02621 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
MFNHADDB_02622 2.8e-28
MFNHADDB_02623 6e-25 ykvS S protein conserved in bacteria
MFNHADDB_02624 2.8e-45 ykvR S Protein of unknown function (DUF3219)
MFNHADDB_02625 6.9e-162 G Glycosyl hydrolases family 18
MFNHADDB_02626 1.1e-31 3.5.1.104 M LysM domain
MFNHADDB_02627 2.1e-232 ykvP 3.5.1.28 M Glycosyl transferases group 1
MFNHADDB_02628 2.4e-133 IQ Enoyl-(Acyl carrier protein) reductase
MFNHADDB_02629 3.4e-61 ykvN K Transcriptional regulator
MFNHADDB_02630 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MFNHADDB_02631 1.1e-138 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MFNHADDB_02632 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
MFNHADDB_02633 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MFNHADDB_02634 1.8e-179 ykvI S membrane
MFNHADDB_02635 0.0 clpE O Belongs to the ClpA ClpB family
MFNHADDB_02636 1e-137 motA N flagellar motor
MFNHADDB_02637 2.5e-125 motB N Flagellar motor protein
MFNHADDB_02638 1.3e-75 ykvE K transcriptional
MFNHADDB_02639 4.8e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
MFNHADDB_02640 1.8e-64 eag
MFNHADDB_02641 6.4e-09 S Spo0E like sporulation regulatory protein
MFNHADDB_02642 4.9e-51 XK27_09985 S Protein of unknown function (DUF1232)
MFNHADDB_02643 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MFNHADDB_02644 2.1e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MFNHADDB_02645 8.3e-136 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MFNHADDB_02646 1.3e-229 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MFNHADDB_02647 9.8e-230 mtnE 2.6.1.83 E Aminotransferase
MFNHADDB_02648 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MFNHADDB_02649 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MFNHADDB_02650 1.3e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MFNHADDB_02652 5e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MFNHADDB_02653 0.0 kinE 2.7.13.3 T Histidine kinase
MFNHADDB_02654 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
MFNHADDB_02655 2.5e-20 ykzE
MFNHADDB_02656 1.2e-10 ydfR S Protein of unknown function (DUF421)
MFNHADDB_02657 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
MFNHADDB_02658 3.9e-154 htpX O Belongs to the peptidase M48B family
MFNHADDB_02659 1.5e-124 ykrK S Domain of unknown function (DUF1836)
MFNHADDB_02660 1.9e-26 sspD S small acid-soluble spore protein
MFNHADDB_02661 4.4e-110 rsgI S Anti-sigma factor N-terminus
MFNHADDB_02662 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MFNHADDB_02663 4.6e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MFNHADDB_02664 3.5e-109 ykoX S membrane-associated protein
MFNHADDB_02665 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
MFNHADDB_02666 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MFNHADDB_02667 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
MFNHADDB_02668 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MFNHADDB_02669 0.0 ykoS
MFNHADDB_02670 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
MFNHADDB_02671 3.7e-99 ykoP G polysaccharide deacetylase
MFNHADDB_02672 2.3e-220 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
MFNHADDB_02673 1.3e-81 mhqR K transcriptional
MFNHADDB_02674 6.9e-26 ykoL
MFNHADDB_02675 5.9e-18
MFNHADDB_02676 1.4e-53 tnrA K transcriptional
MFNHADDB_02677 5e-222 mgtE P Acts as a magnesium transporter
MFNHADDB_02680 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
MFNHADDB_02681 3.1e-111 ykoI S Peptidase propeptide and YPEB domain
MFNHADDB_02682 6.8e-243 ykoH 2.7.13.3 T Histidine kinase
MFNHADDB_02683 2.7e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFNHADDB_02684 1.3e-108 ykoF S YKOF-related Family
MFNHADDB_02685 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
MFNHADDB_02686 4e-306 P ABC transporter, ATP-binding protein
MFNHADDB_02687 2e-135 ykoC P Cobalt transport protein
MFNHADDB_02688 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MFNHADDB_02689 5.5e-175 isp O Belongs to the peptidase S8 family
MFNHADDB_02690 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MFNHADDB_02691 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
MFNHADDB_02692 8.4e-72 ohrB O Organic hydroperoxide resistance protein
MFNHADDB_02693 1.3e-73 ohrR K COG1846 Transcriptional regulators
MFNHADDB_02694 1.3e-70 ohrA O Organic hydroperoxide resistance protein
MFNHADDB_02696 2.8e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MFNHADDB_02697 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MFNHADDB_02698 1.9e-169 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MFNHADDB_02699 7e-50 ykkD P Multidrug resistance protein
MFNHADDB_02700 3.5e-55 ykkC P Multidrug resistance protein
MFNHADDB_02701 8.6e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MFNHADDB_02702 2e-97 ykkA S Protein of unknown function (DUF664)
MFNHADDB_02703 4.6e-129 ykjA S Protein of unknown function (DUF421)
MFNHADDB_02704 1.1e-223 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MFNHADDB_02705 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
MFNHADDB_02706 2e-160 ykgA E Amidinotransferase
MFNHADDB_02707 3.1e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
MFNHADDB_02708 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
MFNHADDB_02709 2.2e-165 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MFNHADDB_02710 3e-201 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MFNHADDB_02711 8.1e-179 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
MFNHADDB_02713 0.0 dppE E ABC transporter substrate-binding protein
MFNHADDB_02714 6.6e-187 dppD P Belongs to the ABC transporter superfamily
MFNHADDB_02715 5.1e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MFNHADDB_02716 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MFNHADDB_02717 5.1e-153 dppA E D-aminopeptidase
MFNHADDB_02718 2.4e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
MFNHADDB_02719 2.6e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MFNHADDB_02721 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MFNHADDB_02722 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MFNHADDB_02723 2.7e-182 mhqA E COG0346 Lactoylglutathione lyase and related lyases
MFNHADDB_02724 1.2e-239 steT E amino acid
MFNHADDB_02725 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
MFNHADDB_02726 5.8e-175 pit P phosphate transporter
MFNHADDB_02727 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
MFNHADDB_02728 6.7e-23 spoIISB S Stage II sporulation protein SB
MFNHADDB_02730 8.6e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MFNHADDB_02731 9.3e-40 xhlB S SPP1 phage holin
MFNHADDB_02732 6.2e-39 xhlA S Haemolysin XhlA
MFNHADDB_02733 6.4e-151 xepA
MFNHADDB_02734 5.5e-22 xkdX
MFNHADDB_02735 1.6e-44 xkdW S XkdW protein
MFNHADDB_02736 1.9e-179
MFNHADDB_02737 8.7e-41
MFNHADDB_02738 5.8e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
MFNHADDB_02739 1.1e-189 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MFNHADDB_02740 2.4e-69 xkdS S Protein of unknown function (DUF2634)
MFNHADDB_02741 6.1e-39 xkdR S Protein of unknown function (DUF2577)
MFNHADDB_02742 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
MFNHADDB_02743 7.8e-118 xkdP S Lysin motif
MFNHADDB_02744 1.2e-268 xkdO L Transglycosylase SLT domain
MFNHADDB_02745 1e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
MFNHADDB_02746 6.1e-76 xkdM S Phage tail tube protein
MFNHADDB_02747 2.5e-256 xkdK S Phage tail sheath C-terminal domain
MFNHADDB_02748 9.3e-77 xkdJ
MFNHADDB_02749 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
MFNHADDB_02750 9e-51 yqbH S Domain of unknown function (DUF3599)
MFNHADDB_02751 5.6e-62 yqbG S Protein of unknown function (DUF3199)
MFNHADDB_02752 5.8e-169 xkdG S Phage capsid family
MFNHADDB_02753 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
MFNHADDB_02754 5.4e-286 yqbA S portal protein
MFNHADDB_02755 9.6e-255 xtmB S phage terminase, large subunit
MFNHADDB_02756 4.8e-140 xtmA L phage terminase small subunit
MFNHADDB_02757 4.4e-86 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MFNHADDB_02758 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
MFNHADDB_02761 6.4e-119 xkdC L Bacterial dnaA protein
MFNHADDB_02762 5.9e-157 xkdB K sequence-specific DNA binding
MFNHADDB_02764 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
MFNHADDB_02765 1.6e-111 xkdA E IrrE N-terminal-like domain
MFNHADDB_02766 4.4e-160 ydbD P Catalase
MFNHADDB_02767 4.2e-112 yjqB S Pfam:DUF867
MFNHADDB_02768 2.1e-61 yjqA S Bacterial PH domain
MFNHADDB_02769 9.1e-170 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
MFNHADDB_02770 6.3e-41 S YCII-related domain
MFNHADDB_02772 2.1e-213 S response regulator aspartate phosphatase
MFNHADDB_02773 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
MFNHADDB_02774 3.3e-80 yjoA S DinB family
MFNHADDB_02775 4.3e-130 MA20_18170 S membrane transporter protein
MFNHADDB_02776 2e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
MFNHADDB_02777 4.9e-284 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
MFNHADDB_02778 1.5e-183 exuR K transcriptional
MFNHADDB_02779 5.9e-225 exuT G Sugar (and other) transporter
MFNHADDB_02780 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MFNHADDB_02781 5.2e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
MFNHADDB_02782 2.5e-189 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
MFNHADDB_02783 4.2e-189 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MFNHADDB_02784 2.4e-248 yjmB G symporter YjmB
MFNHADDB_02785 7.9e-279 uxaC 5.3.1.12 G glucuronate isomerase
MFNHADDB_02786 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
MFNHADDB_02787 7.1e-66 yjlC S Protein of unknown function (DUF1641)
MFNHADDB_02788 1.7e-90 yjlB S Cupin domain
MFNHADDB_02789 1.9e-175 yjlA EG Putative multidrug resistance efflux transporter
MFNHADDB_02790 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
MFNHADDB_02791 5.6e-122 ybbM S transport system, permease component
MFNHADDB_02792 2.5e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MFNHADDB_02793 8.2e-30
MFNHADDB_02794 3.2e-217 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MFNHADDB_02795 1.8e-220 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
MFNHADDB_02797 1.9e-115 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
MFNHADDB_02798 1.5e-06 S Domain of unknown function (DUF4352)
MFNHADDB_02799 5.7e-95 yjgD S Protein of unknown function (DUF1641)
MFNHADDB_02800 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
MFNHADDB_02801 2e-103 yjgB S Domain of unknown function (DUF4309)
MFNHADDB_02802 6e-45 T PhoQ Sensor
MFNHADDB_02803 1.1e-167 yjfC O Predicted Zn-dependent protease (DUF2268)
MFNHADDB_02804 2.3e-20 yjfB S Putative motility protein
MFNHADDB_02805 8.8e-81 S Protein of unknown function (DUF2690)
MFNHADDB_02806 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
MFNHADDB_02808 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MFNHADDB_02809 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
MFNHADDB_02810 4.2e-29 S Domain of unknown function (DUF4177)
MFNHADDB_02811 1.4e-78 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MFNHADDB_02813 1.1e-89 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
MFNHADDB_02814 4.5e-49 yjdF S Protein of unknown function (DUF2992)
MFNHADDB_02815 2.1e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
MFNHADDB_02816 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
MFNHADDB_02817 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
MFNHADDB_02819 9.2e-141 IQ Enoyl-(Acyl carrier protein) reductase
MFNHADDB_02820 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
MFNHADDB_02822 9e-19
MFNHADDB_02823 1.9e-36
MFNHADDB_02824 4.3e-11 S YolD-like protein
MFNHADDB_02825 2.4e-29 KLT Protein tyrosine kinase
MFNHADDB_02827 5e-238 M nucleic acid phosphodiester bond hydrolysis
MFNHADDB_02828 1e-29
MFNHADDB_02829 1.3e-37
MFNHADDB_02832 1.3e-210 yjcL S Protein of unknown function (DUF819)
MFNHADDB_02833 5.3e-98 rimJ 2.3.1.128 J Alanine acetyltransferase
MFNHADDB_02834 2.5e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MFNHADDB_02835 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MFNHADDB_02836 7e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
MFNHADDB_02837 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
MFNHADDB_02838 6.6e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MFNHADDB_02839 1.7e-38
MFNHADDB_02840 0.0 yjcD 3.6.4.12 L DNA helicase
MFNHADDB_02841 2.9e-38 spoVIF S Stage VI sporulation protein F
MFNHADDB_02844 1.9e-56 yjcA S Protein of unknown function (DUF1360)
MFNHADDB_02845 3.2e-49 cotV S Spore Coat Protein X and V domain
MFNHADDB_02846 7.4e-23 cotW
MFNHADDB_02847 1.2e-67 cotX S Spore Coat Protein X and V domain
MFNHADDB_02848 7.6e-96 cotY S Spore coat protein Z
MFNHADDB_02849 4.4e-82 cotZ S Spore coat protein
MFNHADDB_02850 6.5e-53 yjbX S Spore coat protein
MFNHADDB_02851 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MFNHADDB_02852 2e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MFNHADDB_02853 5.6e-186 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MFNHADDB_02854 4.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MFNHADDB_02855 6.7e-30 thiS H thiamine diphosphate biosynthetic process
MFNHADDB_02856 2.3e-217 thiO 1.4.3.19 E Glycine oxidase
MFNHADDB_02857 3.8e-108 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
MFNHADDB_02858 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MFNHADDB_02859 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MFNHADDB_02860 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MFNHADDB_02861 9.5e-161 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MFNHADDB_02862 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MFNHADDB_02863 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
MFNHADDB_02864 7.8e-61 yjbL S Belongs to the UPF0738 family
MFNHADDB_02865 1e-99 yjbK S protein conserved in bacteria
MFNHADDB_02866 2.5e-82 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MFNHADDB_02867 3.7e-72 yjbI S Bacterial-like globin
MFNHADDB_02868 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MFNHADDB_02869 1.8e-20
MFNHADDB_02870 0.0 pepF E oligoendopeptidase F
MFNHADDB_02871 1.8e-220 yjbF S Competence protein
MFNHADDB_02872 8.9e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MFNHADDB_02873 6e-112 yjbE P Integral membrane protein TerC family
MFNHADDB_02874 2.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MFNHADDB_02875 6.9e-104 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MFNHADDB_02876 8.6e-196 yjbB EGP Major Facilitator Superfamily
MFNHADDB_02877 5.5e-172 oppF E Belongs to the ABC transporter superfamily
MFNHADDB_02878 3e-198 oppD P Belongs to the ABC transporter superfamily
MFNHADDB_02879 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MFNHADDB_02880 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MFNHADDB_02881 0.0 oppA E ABC transporter substrate-binding protein
MFNHADDB_02882 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
MFNHADDB_02883 5e-147 yjbA S Belongs to the UPF0736 family
MFNHADDB_02884 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MFNHADDB_02885 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MFNHADDB_02886 1.6e-251 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
MFNHADDB_02887 6.5e-187 appF E Belongs to the ABC transporter superfamily
MFNHADDB_02888 1.8e-184 appD P Belongs to the ABC transporter superfamily
MFNHADDB_02889 7.8e-151 yjaZ O Zn-dependent protease
MFNHADDB_02890 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MFNHADDB_02891 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MFNHADDB_02892 2.7e-22 yjzB
MFNHADDB_02893 7.3e-26 comZ S ComZ
MFNHADDB_02894 1.1e-183 med S Transcriptional activator protein med
MFNHADDB_02895 7.3e-103 yjaV
MFNHADDB_02896 6.2e-142 yjaU I carboxylic ester hydrolase activity
MFNHADDB_02897 2.3e-16 yjzD S Protein of unknown function (DUF2929)
MFNHADDB_02898 9.5e-28 yjzC S YjzC-like protein
MFNHADDB_02899 3.8e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MFNHADDB_02900 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
MFNHADDB_02901 3.3e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MFNHADDB_02902 4.4e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
MFNHADDB_02903 2.2e-137 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MFNHADDB_02904 3.1e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MFNHADDB_02905 3.5e-199 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MFNHADDB_02906 1.7e-88 norB G Major Facilitator Superfamily
MFNHADDB_02907 4.3e-272 yitY C D-arabinono-1,4-lactone oxidase
MFNHADDB_02908 1.5e-22 pilT S Proteolipid membrane potential modulator
MFNHADDB_02909 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
MFNHADDB_02910 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
MFNHADDB_02911 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
MFNHADDB_02913 2.8e-17 S Protein of unknown function (DUF3813)
MFNHADDB_02914 5e-73 ipi S Intracellular proteinase inhibitor
MFNHADDB_02915 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
MFNHADDB_02916 8.4e-159 yitS S protein conserved in bacteria
MFNHADDB_02917 2.7e-307 nprB 3.4.24.28 E Peptidase M4
MFNHADDB_02918 1.4e-44 yitR S Domain of unknown function (DUF3784)
MFNHADDB_02919 2.5e-93
MFNHADDB_02920 4.5e-58 K Transcriptional regulator PadR-like family
MFNHADDB_02921 1.5e-97 S Sporulation delaying protein SdpA
MFNHADDB_02922 2.8e-171
MFNHADDB_02923 8.5e-94
MFNHADDB_02924 4e-161 cvfB S protein conserved in bacteria
MFNHADDB_02925 8.6e-55 yajQ S Belongs to the UPF0234 family
MFNHADDB_02926 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MFNHADDB_02927 4.6e-71 yjcF S Acetyltransferase (GNAT) domain
MFNHADDB_02928 1.8e-156 yitH K Acetyltransferase (GNAT) domain
MFNHADDB_02929 4e-229 yitG EGP Major facilitator Superfamily
MFNHADDB_02930 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MFNHADDB_02931 7.2e-113 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MFNHADDB_02932 1.9e-141 yitD 4.4.1.19 S synthase
MFNHADDB_02933 4.9e-125 comB 3.1.3.71 H Belongs to the ComB family
MFNHADDB_02934 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MFNHADDB_02935 3.2e-233 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MFNHADDB_02936 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
MFNHADDB_02937 4.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MFNHADDB_02938 2.2e-34 mcbG S Pentapeptide repeats (9 copies)
MFNHADDB_02939 5.8e-277 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MFNHADDB_02940 5e-105 argO S Lysine exporter protein LysE YggA
MFNHADDB_02941 8.2e-93 yisT S DinB family
MFNHADDB_02942 3.7e-193 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
MFNHADDB_02943 1.1e-181 purR K helix_turn _helix lactose operon repressor
MFNHADDB_02944 3.5e-160 yisR K Transcriptional regulator
MFNHADDB_02945 1.5e-242 yisQ V Mate efflux family protein
MFNHADDB_02946 1.7e-148 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
MFNHADDB_02947 6.4e-88 yizA S Damage-inducible protein DinB
MFNHADDB_02948 0.0 asnO 6.3.5.4 E Asparagine synthase
MFNHADDB_02949 1.3e-102 yisN S Protein of unknown function (DUF2777)
MFNHADDB_02950 0.0 wprA O Belongs to the peptidase S8 family
MFNHADDB_02951 3e-57 yisL S UPF0344 protein
MFNHADDB_02952 7.1e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MFNHADDB_02953 3.1e-175 cotH M Spore Coat
MFNHADDB_02954 1.5e-22 yisI S Spo0E like sporulation regulatory protein
MFNHADDB_02955 1.9e-33 gerPA S Spore germination protein
MFNHADDB_02956 4e-34 gerPB S cell differentiation
MFNHADDB_02957 1.8e-54 gerPC S Spore germination protein
MFNHADDB_02958 6.3e-24 gerPD S Spore germination protein
MFNHADDB_02959 3e-66 gerPE S Spore germination protein GerPE
MFNHADDB_02960 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
MFNHADDB_02961 3e-50 yisB V COG1403 Restriction endonuclease
MFNHADDB_02962 0.0 sbcC L COG0419 ATPase involved in DNA repair
MFNHADDB_02963 1.7e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MFNHADDB_02964 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MFNHADDB_02965 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
MFNHADDB_02966 2.2e-78 yhjR S Rubrerythrin
MFNHADDB_02967 2e-36 yhjQ C COG1145 Ferredoxin
MFNHADDB_02968 0.0 S Sugar transport-related sRNA regulator N-term
MFNHADDB_02969 9e-215 EGP Transmembrane secretion effector
MFNHADDB_02970 1.9e-201 abrB S membrane
MFNHADDB_02971 1.7e-187 yhjM 5.1.1.1 K Transcriptional regulator
MFNHADDB_02972 1.8e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
MFNHADDB_02973 2.6e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
MFNHADDB_02974 6e-199 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
MFNHADDB_02975 3.8e-213 glcP G Major Facilitator Superfamily
MFNHADDB_02976 4.5e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
MFNHADDB_02977 1.2e-280 yhjG CH FAD binding domain
MFNHADDB_02978 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
MFNHADDB_02979 9.1e-110 yhjE S SNARE associated Golgi protein
MFNHADDB_02980 5e-60 yhjD
MFNHADDB_02981 3.4e-26 yhjC S Protein of unknown function (DUF3311)
MFNHADDB_02982 2.3e-265 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MFNHADDB_02983 2.8e-39 yhjA S Excalibur calcium-binding domain
MFNHADDB_02984 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
MFNHADDB_02985 9.3e-109 comK K Competence transcription factor
MFNHADDB_02986 1.3e-32 yhzC S IDEAL
MFNHADDB_02987 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFNHADDB_02988 1.1e-302 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
MFNHADDB_02989 1.7e-182 hemAT NT chemotaxis protein
MFNHADDB_02990 5e-91 bioY S BioY family
MFNHADDB_02991 1.9e-275 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MFNHADDB_02992 1.1e-195 vraB 2.3.1.9 I Belongs to the thiolase family
MFNHADDB_02993 7.1e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
MFNHADDB_02994 4.3e-159 yfmC M Periplasmic binding protein
MFNHADDB_02995 4.5e-180 yhfP 1.1.1.1 C Quinone oxidoreductase
MFNHADDB_02996 3.6e-76 VY92_01935 K acetyltransferase
MFNHADDB_02997 5.6e-198 aprE 3.4.21.62 O Belongs to the peptidase S8 family
MFNHADDB_02998 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
MFNHADDB_02999 1.9e-65 yhfM
MFNHADDB_03000 7e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MFNHADDB_03001 1.1e-110 yhfK GM NmrA-like family
MFNHADDB_03002 4.9e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
MFNHADDB_03003 5.2e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MFNHADDB_03004 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MFNHADDB_03005 1.4e-71 3.4.13.21 S ASCH
MFNHADDB_03006 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
MFNHADDB_03007 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
MFNHADDB_03008 8.1e-182 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MFNHADDB_03009 8.6e-238 yhgE S YhgE Pip N-terminal domain protein
MFNHADDB_03010 5.4e-101 yhgD K Transcriptional regulator
MFNHADDB_03011 9.1e-267 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MFNHADDB_03012 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MFNHADDB_03013 4.1e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MFNHADDB_03014 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MFNHADDB_03015 2.9e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
MFNHADDB_03016 2.6e-17 1.15.1.2 C Rubrerythrin
MFNHADDB_03017 2.5e-245 yhfA C membrane
MFNHADDB_03018 2.2e-229 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MFNHADDB_03019 5.3e-114 ecsC S EcsC protein family
MFNHADDB_03020 5.4e-215 ecsB U ABC transporter
MFNHADDB_03021 4.6e-137 ecsA V transporter (ATP-binding protein)
MFNHADDB_03022 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MFNHADDB_03023 7.1e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MFNHADDB_03024 3.1e-79 trpP S Tryptophan transporter TrpP
MFNHADDB_03025 5.4e-21
MFNHADDB_03026 7e-39 yhaH S YtxH-like protein
MFNHADDB_03027 2.3e-113 hpr K Negative regulator of protease production and sporulation
MFNHADDB_03028 1.3e-54 yhaI S Protein of unknown function (DUF1878)
MFNHADDB_03029 7.3e-89 yhaK S Putative zincin peptidase
MFNHADDB_03030 1.1e-116 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MFNHADDB_03031 1.6e-21 yhaL S Sporulation protein YhaL
MFNHADDB_03032 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
MFNHADDB_03033 0.0 yhaN L AAA domain
MFNHADDB_03034 5.7e-225 yhaO L DNA repair exonuclease
MFNHADDB_03035 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
MFNHADDB_03036 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
MFNHADDB_03037 1.1e-26 S YhzD-like protein
MFNHADDB_03038 3.2e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
MFNHADDB_03040 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
MFNHADDB_03041 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
MFNHADDB_03042 1.8e-292 hemZ H coproporphyrinogen III oxidase
MFNHADDB_03043 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
MFNHADDB_03044 7.8e-202 yhaZ L DNA alkylation repair enzyme
MFNHADDB_03045 9.5e-48 yheA S Belongs to the UPF0342 family
MFNHADDB_03046 1.4e-201 yheB S Belongs to the UPF0754 family
MFNHADDB_03047 4.3e-216 yheC HJ YheC/D like ATP-grasp
MFNHADDB_03048 1e-267 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
MFNHADDB_03049 6.5e-36 yheE S Family of unknown function (DUF5342)
MFNHADDB_03050 6.3e-28 sspB S spore protein
MFNHADDB_03051 9e-110 yheG GM NAD(P)H-binding
MFNHADDB_03052 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
MFNHADDB_03053 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
MFNHADDB_03054 1.5e-83 nhaX T Belongs to the universal stress protein A family
MFNHADDB_03055 2.9e-230 nhaC C Na H antiporter
MFNHADDB_03056 3.4e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MFNHADDB_03057 3.8e-151 yheN G deacetylase
MFNHADDB_03058 2.6e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MFNHADDB_03059 9.9e-184 yhdY M Mechanosensitive ion channel
MFNHADDB_03061 1.8e-133 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MFNHADDB_03062 2.1e-64 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MFNHADDB_03063 6.2e-47 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MFNHADDB_03064 3.9e-246 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
MFNHADDB_03065 8.8e-223 yhdR 2.6.1.1 E Aminotransferase
MFNHADDB_03066 4.1e-74 cueR K transcriptional
MFNHADDB_03067 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MFNHADDB_03068 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MFNHADDB_03069 1.5e-191 yhdN C Aldo keto reductase
MFNHADDB_03070 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
MFNHADDB_03071 6.6e-201 yhdL S Sigma factor regulator N-terminal
MFNHADDB_03072 8.1e-45 yhdK S Sigma-M inhibitor protein
MFNHADDB_03073 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MFNHADDB_03074 3.1e-267 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MFNHADDB_03075 1.3e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MFNHADDB_03076 5.9e-250 yhdG E amino acid
MFNHADDB_03077 1e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFNHADDB_03078 2.5e-203 citA 2.3.3.1 C Belongs to the citrate synthase family
MFNHADDB_03079 3.8e-162 citR K Transcriptional regulator
MFNHADDB_03080 5.3e-128 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MFNHADDB_03081 1.9e-256 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
MFNHADDB_03082 2.1e-276 ycgB S Stage V sporulation protein R
MFNHADDB_03083 1.5e-238 ygxB M Conserved TM helix
MFNHADDB_03084 1e-75 nsrR K Transcriptional regulator
MFNHADDB_03085 4.3e-187 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MFNHADDB_03086 4.5e-52 yhdC S Protein of unknown function (DUF3889)
MFNHADDB_03087 1.2e-38 yhdB S YhdB-like protein
MFNHADDB_03088 1.9e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
MFNHADDB_03089 5e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MFNHADDB_03090 4e-212 yhcY 2.7.13.3 T Histidine kinase
MFNHADDB_03091 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
MFNHADDB_03092 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MFNHADDB_03093 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MFNHADDB_03094 5.7e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
MFNHADDB_03095 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MFNHADDB_03096 4.6e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MFNHADDB_03097 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MFNHADDB_03098 1.3e-119 yhcW 5.4.2.6 S hydrolase
MFNHADDB_03099 9.9e-68 yhcV S COG0517 FOG CBS domain
MFNHADDB_03100 2.1e-67 yhcU S Family of unknown function (DUF5365)
MFNHADDB_03101 7.3e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MFNHADDB_03102 6e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
MFNHADDB_03103 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
MFNHADDB_03104 4.4e-99 yhcQ M Spore coat protein
MFNHADDB_03105 1.3e-166 yhcP
MFNHADDB_03106 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MFNHADDB_03107 1.1e-40 yhcM
MFNHADDB_03108 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MFNHADDB_03109 2.9e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
MFNHADDB_03110 4.4e-152 metQ M Belongs to the nlpA lipoprotein family
MFNHADDB_03111 1e-30 cspB K Cold-shock protein
MFNHADDB_03112 5.6e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MFNHADDB_03113 7.7e-166 yhcH V ABC transporter, ATP-binding protein
MFNHADDB_03114 1.6e-123 yhcG V ABC transporter, ATP-binding protein
MFNHADDB_03115 6.6e-60 yhcF K Transcriptional regulator
MFNHADDB_03116 2e-55
MFNHADDB_03117 2.8e-37 yhcC
MFNHADDB_03118 1.4e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
MFNHADDB_03119 3.1e-271 yhcA EGP Major facilitator Superfamily
MFNHADDB_03120 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
MFNHADDB_03121 2.2e-76 yhbI K DNA-binding transcription factor activity
MFNHADDB_03122 2.5e-225 yhbH S Belongs to the UPF0229 family
MFNHADDB_03123 0.0 prkA T Ser protein kinase
MFNHADDB_03124 7.2e-71 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
MFNHADDB_03125 1e-64 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
MFNHADDB_03126 1.2e-109 yhbD K Protein of unknown function (DUF4004)
MFNHADDB_03127 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MFNHADDB_03128 2.4e-175 yhbB S Putative amidase domain
MFNHADDB_03129 2.3e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MFNHADDB_03130 7.9e-114 yhzB S B3/4 domain
MFNHADDB_03132 4.4e-29 K Transcriptional regulator
MFNHADDB_03133 4.1e-78 ygaO
MFNHADDB_03134 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MFNHADDB_03136 2e-216 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
MFNHADDB_03137 4.2e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MFNHADDB_03138 1.6e-169 ssuA M Sulfonate ABC transporter
MFNHADDB_03139 3e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MFNHADDB_03140 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MFNHADDB_03142 4.5e-263 ygaK C Berberine and berberine like
MFNHADDB_03143 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MFNHADDB_03144 1.6e-131 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
MFNHADDB_03145 1.2e-26
MFNHADDB_03146 7.7e-143 spo0M S COG4326 Sporulation control protein
MFNHADDB_03150 2e-08
MFNHADDB_03157 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFNHADDB_03158 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
MFNHADDB_03159 2.2e-139 srfAD Q thioesterase
MFNHADDB_03160 1.5e-225 EGP Major Facilitator Superfamily
MFNHADDB_03161 3e-88 S YcxB-like protein
MFNHADDB_03162 1.9e-159 ycxC EG EamA-like transporter family
MFNHADDB_03163 6.5e-159 ycxD K GntR family transcriptional regulator
MFNHADDB_03164 2.6e-80 ycxD K GntR family transcriptional regulator
MFNHADDB_03165 2.9e-114 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
MFNHADDB_03166 1.7e-114 yczE S membrane
MFNHADDB_03167 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MFNHADDB_03168 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
MFNHADDB_03169 6.4e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MFNHADDB_03170 1.9e-161 bsdA K LysR substrate binding domain
MFNHADDB_03171 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MFNHADDB_03172 4.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MFNHADDB_03173 4e-39 bsdD 4.1.1.61 S response to toxic substance
MFNHADDB_03174 2.1e-79 yclD
MFNHADDB_03175 3.2e-158 yclE 3.4.11.5 S Alpha beta hydrolase
MFNHADDB_03176 4.7e-266 dtpT E amino acid peptide transporter
MFNHADDB_03177 2.7e-308 yclG M Pectate lyase superfamily protein
MFNHADDB_03179 1.5e-281 gerKA EG Spore germination protein
MFNHADDB_03180 1.3e-232 gerKC S spore germination
MFNHADDB_03181 4.9e-199 gerKB F Spore germination protein
MFNHADDB_03182 3.9e-122 yclH P ABC transporter
MFNHADDB_03183 3.9e-204 yclI V ABC transporter (permease) YclI
MFNHADDB_03184 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFNHADDB_03185 1.8e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MFNHADDB_03186 2e-70 S aspartate phosphatase
MFNHADDB_03189 5.7e-250 lysC 2.7.2.4 E Belongs to the aspartokinase family
MFNHADDB_03190 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFNHADDB_03191 1.3e-163 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFNHADDB_03192 1.1e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
MFNHADDB_03193 1.4e-170 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
MFNHADDB_03194 4.1e-251 ycnB EGP Major facilitator Superfamily
MFNHADDB_03195 5.5e-153 ycnC K Transcriptional regulator
MFNHADDB_03196 2.2e-134 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
MFNHADDB_03197 1.6e-45 ycnE S Monooxygenase
MFNHADDB_03198 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
MFNHADDB_03199 1.5e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MFNHADDB_03200 3.1e-245 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MFNHADDB_03201 3.8e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MFNHADDB_03202 6.1e-149 glcU U Glucose uptake
MFNHADDB_03203 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFNHADDB_03204 1.4e-99 ycnI S protein conserved in bacteria
MFNHADDB_03205 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
MFNHADDB_03206 4.3e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
MFNHADDB_03207 7.3e-56
MFNHADDB_03208 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
MFNHADDB_03209 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MFNHADDB_03210 1.8e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
MFNHADDB_03211 1.6e-199 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
MFNHADDB_03212 4.1e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MFNHADDB_03213 1.3e-75 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MFNHADDB_03214 6.8e-110 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
MFNHADDB_03215 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
MFNHADDB_03217 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
MFNHADDB_03218 2.7e-140 ycsF S Belongs to the UPF0271 (lamB) family
MFNHADDB_03219 2.1e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
MFNHADDB_03220 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
MFNHADDB_03221 1.4e-133 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
MFNHADDB_03222 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
MFNHADDB_03223 2.7e-132 kipR K Transcriptional regulator
MFNHADDB_03224 1.3e-119 ycsK E anatomical structure formation involved in morphogenesis
MFNHADDB_03226 9.2e-49 yczJ S biosynthesis
MFNHADDB_03227 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
MFNHADDB_03228 8.3e-173 ydhF S Oxidoreductase
MFNHADDB_03229 0.0 mtlR K transcriptional regulator, MtlR
MFNHADDB_03230 3.2e-294 ydaB IQ acyl-CoA ligase
MFNHADDB_03231 1.1e-99 ydaC Q Methyltransferase domain
MFNHADDB_03232 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFNHADDB_03233 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
MFNHADDB_03234 5e-104 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MFNHADDB_03235 6.8e-77 ydaG 1.4.3.5 S general stress protein
MFNHADDB_03236 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MFNHADDB_03237 5.1e-47 ydzA EGP Major facilitator Superfamily
MFNHADDB_03238 2.5e-74 lrpC K Transcriptional regulator
MFNHADDB_03239 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MFNHADDB_03240 1.8e-206 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
MFNHADDB_03241 3.6e-149 ydaK T Diguanylate cyclase, GGDEF domain
MFNHADDB_03242 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
MFNHADDB_03243 1.3e-232 ydaM M Glycosyl transferase family group 2
MFNHADDB_03244 0.0 ydaN S Bacterial cellulose synthase subunit
MFNHADDB_03245 0.0 ydaO E amino acid
MFNHADDB_03246 3.9e-78 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
MFNHADDB_03247 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MFNHADDB_03248 9.4e-40
MFNHADDB_03249 3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
MFNHADDB_03251 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
MFNHADDB_03252 2.4e-147 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
MFNHADDB_03254 8.9e-59 ydbB G Cupin domain
MFNHADDB_03255 1.8e-62 ydbC S Domain of unknown function (DUF4937
MFNHADDB_03256 5.1e-153 ydbD P Catalase
MFNHADDB_03257 2.5e-197 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MFNHADDB_03258 4.8e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MFNHADDB_03259 1.8e-119 dctR T COG4565 Response regulator of citrate malate metabolism
MFNHADDB_03260 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MFNHADDB_03261 9.7e-181 ydbI S AI-2E family transporter
MFNHADDB_03262 4.7e-171 ydbJ V ABC transporter, ATP-binding protein
MFNHADDB_03263 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MFNHADDB_03264 2.7e-52 ydbL
MFNHADDB_03265 5.2e-220 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
MFNHADDB_03266 1.1e-18 S Fur-regulated basic protein B
MFNHADDB_03267 2.2e-07 S Fur-regulated basic protein A
MFNHADDB_03268 5.6e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MFNHADDB_03269 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MFNHADDB_03270 5.1e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MFNHADDB_03271 4.1e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MFNHADDB_03272 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MFNHADDB_03273 2.1e-82 ydbS S Bacterial PH domain
MFNHADDB_03274 2.5e-259 ydbT S Membrane
MFNHADDB_03275 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
MFNHADDB_03276 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MFNHADDB_03277 8.5e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
MFNHADDB_03278 6.9e-220 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MFNHADDB_03279 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MFNHADDB_03280 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
MFNHADDB_03281 1.3e-143 rsbR T Positive regulator of sigma-B
MFNHADDB_03282 5.2e-57 rsbS T antagonist
MFNHADDB_03283 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MFNHADDB_03284 7.1e-189 rsbU 3.1.3.3 KT phosphatase
MFNHADDB_03285 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
MFNHADDB_03286 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MFNHADDB_03287 5.8e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MFNHADDB_03288 1.1e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
MFNHADDB_03289 0.0 yhgF K COG2183 Transcriptional accessory protein
MFNHADDB_03290 3.4e-82 ydcK S Belongs to the SprT family
MFNHADDB_03298 2.3e-72 rimJ2 J Acetyltransferase (GNAT) domain
MFNHADDB_03299 4.2e-44
MFNHADDB_03300 1.8e-20 S LXG domain of WXG superfamily
MFNHADDB_03301 8.1e-24 L HNH endonuclease
MFNHADDB_03302 6.4e-45 L HNH nucleases
MFNHADDB_03306 8e-10
MFNHADDB_03309 5.6e-34 K Helix-turn-helix XRE-family like proteins
MFNHADDB_03310 2.5e-40
MFNHADDB_03314 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
MFNHADDB_03315 8.7e-30 cspL K Cold shock
MFNHADDB_03316 3e-78 carD K Transcription factor
MFNHADDB_03317 2.1e-144 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MFNHADDB_03318 3.6e-165 rhaS5 K AraC-like ligand binding domain
MFNHADDB_03319 3.4e-172 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MFNHADDB_03320 3.4e-163 ydeE K AraC family transcriptional regulator
MFNHADDB_03321 1.7e-262 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MFNHADDB_03322 1.2e-217 ydeG EGP Major facilitator superfamily
MFNHADDB_03323 1.4e-44 ydeH
MFNHADDB_03324 6.4e-105 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
MFNHADDB_03325 6.9e-108
MFNHADDB_03326 5.8e-77 ksgA1 I Ribosomal RNA adenine dimethylase
MFNHADDB_03327 2.5e-113 T Transcriptional regulator
MFNHADDB_03328 1.4e-139 T PhoQ Sensor
MFNHADDB_03329 8.4e-71 S SNARE associated Golgi protein
MFNHADDB_03330 3.7e-15 ptsH G PTS HPr component phosphorylation site
MFNHADDB_03331 8.8e-85 K Transcriptional regulator C-terminal region
MFNHADDB_03332 5e-151 ydeK EG -transporter
MFNHADDB_03333 6.4e-273 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MFNHADDB_03334 4.2e-74 maoC I N-terminal half of MaoC dehydratase
MFNHADDB_03335 8.6e-107 ydeN S Serine hydrolase
MFNHADDB_03336 1.1e-58 K HxlR-like helix-turn-helix
MFNHADDB_03337 5.4e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MFNHADDB_03338 1e-194 ydeR EGP Major facilitator Superfamily
MFNHADDB_03339 8.4e-105 ydeS K Transcriptional regulator
MFNHADDB_03340 1.3e-57 arsR K transcriptional
MFNHADDB_03341 5.2e-232 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MFNHADDB_03342 1.5e-146 ydfB J GNAT acetyltransferase
MFNHADDB_03343 1.5e-153 ydfC EG EamA-like transporter family
MFNHADDB_03344 8.7e-273 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MFNHADDB_03345 5e-116 ydfE S Flavin reductase like domain
MFNHADDB_03346 4.6e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
MFNHADDB_03347 6.5e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MFNHADDB_03349 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
MFNHADDB_03350 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MFNHADDB_03351 0.0 ydfJ S drug exporters of the RND superfamily
MFNHADDB_03352 3.7e-173 S Alpha/beta hydrolase family
MFNHADDB_03353 7.2e-116 S Protein of unknown function (DUF554)
MFNHADDB_03354 6.6e-145 K Bacterial transcription activator, effector binding domain
MFNHADDB_03355 6.6e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MFNHADDB_03356 9.6e-112 ydfN C nitroreductase
MFNHADDB_03357 1.5e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
MFNHADDB_03358 8.8e-63 mhqP S DoxX
MFNHADDB_03359 1.6e-55 traF CO Thioredoxin
MFNHADDB_03360 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
MFNHADDB_03361 6.3e-29
MFNHADDB_03363 4.4e-118 ydfR S Protein of unknown function (DUF421)
MFNHADDB_03364 5.2e-122 ydfS S Protein of unknown function (DUF421)
MFNHADDB_03365 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
MFNHADDB_03366 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
MFNHADDB_03367 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
MFNHADDB_03368 1.5e-98 K Bacterial regulatory proteins, tetR family
MFNHADDB_03369 9e-51 S DoxX-like family
MFNHADDB_03370 1.3e-84 yycN 2.3.1.128 K Acetyltransferase
MFNHADDB_03371 5.1e-134 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
MFNHADDB_03372 2e-119 purR K helix_turn _helix lactose operon repressor
MFNHADDB_03373 1.7e-190 csbC EGP Major facilitator Superfamily
MFNHADDB_03374 7.5e-104 G Xylose isomerase-like TIM barrel
MFNHADDB_03375 1.8e-303 expZ S ABC transporter
MFNHADDB_03376 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
MFNHADDB_03377 3e-90 dinB S DinB family
MFNHADDB_03378 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
MFNHADDB_03379 0.0 ydgH S drug exporters of the RND superfamily
MFNHADDB_03380 1e-113 drgA C nitroreductase
MFNHADDB_03381 2.4e-69 ydgJ K Winged helix DNA-binding domain
MFNHADDB_03382 6.3e-208 tcaB EGP Major facilitator Superfamily
MFNHADDB_03383 1.2e-121 ydhB S membrane transporter protein
MFNHADDB_03384 1.6e-120 ydhC K FCD
MFNHADDB_03385 1.1e-242 ydhD M Glycosyl hydrolase
MFNHADDB_03386 9.1e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MFNHADDB_03387 6.2e-123
MFNHADDB_03388 5.2e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
MFNHADDB_03389 4.3e-67 frataxin S Domain of unknown function (DU1801)
MFNHADDB_03391 4.7e-82 K Acetyltransferase (GNAT) domain
MFNHADDB_03392 2.9e-179 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MFNHADDB_03393 9.4e-98 ydhK M Protein of unknown function (DUF1541)
MFNHADDB_03394 4.6e-200 pbuE EGP Major facilitator Superfamily
MFNHADDB_03395 1.1e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
MFNHADDB_03396 3e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
MFNHADDB_03397 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFNHADDB_03398 2.4e-283 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MFNHADDB_03399 1.1e-132 ydhQ K UTRA
MFNHADDB_03400 8e-168 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
MFNHADDB_03401 1.1e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
MFNHADDB_03402 2e-213 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
MFNHADDB_03403 6.1e-157 ydhU P Catalase
MFNHADDB_03406 8.4e-208 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
MFNHADDB_03408 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
MFNHADDB_03409 1e-136 ybbA S Putative esterase
MFNHADDB_03410 5.6e-178 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFNHADDB_03411 3.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFNHADDB_03412 1.4e-165 feuA P Iron-uptake system-binding protein
MFNHADDB_03413 2.5e-305 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
MFNHADDB_03414 2.7e-238 ybbC 3.2.1.52 S protein conserved in bacteria
MFNHADDB_03415 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
MFNHADDB_03416 3.1e-253 yfeW 3.4.16.4 V Belongs to the UPF0214 family
MFNHADDB_03417 1.3e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MFNHADDB_03418 2.3e-148 ybbH K transcriptional
MFNHADDB_03419 8.8e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MFNHADDB_03420 7.1e-86 ybbJ J acetyltransferase
MFNHADDB_03421 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
MFNHADDB_03427 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
MFNHADDB_03428 6.3e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MFNHADDB_03429 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MFNHADDB_03430 1.5e-224 ybbR S protein conserved in bacteria
MFNHADDB_03431 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MFNHADDB_03432 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MFNHADDB_03433 1e-170 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MFNHADDB_03434 6.4e-119 adaA 3.2.2.21 K Transcriptional regulator
MFNHADDB_03435 9.6e-100 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MFNHADDB_03436 4.1e-273 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MFNHADDB_03437 0.0 ybcC S Belongs to the UPF0753 family
MFNHADDB_03438 1.1e-92 can 4.2.1.1 P carbonic anhydrase
MFNHADDB_03439 6.2e-45
MFNHADDB_03440 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
MFNHADDB_03441 5.1e-50 ybzH K Helix-turn-helix domain
MFNHADDB_03442 7.2e-201 ybcL EGP Major facilitator Superfamily
MFNHADDB_03444 2.8e-33 O Subtilase family
MFNHADDB_03445 2.5e-123 spaB S Lantibiotic dehydratase, C terminus
MFNHADDB_03446 3.7e-60 spaC1 V Lanthionine synthetase C-like protein
MFNHADDB_03448 1.4e-144 msbA2 3.6.3.44 V ABC transporter
MFNHADDB_03449 1.4e-181 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MFNHADDB_03450 4.2e-121 T Transcriptional regulatory protein, C terminal
MFNHADDB_03451 2.2e-171 T His Kinase A (phospho-acceptor) domain
MFNHADDB_03453 3.7e-137 KLT Protein tyrosine kinase
MFNHADDB_03454 3.8e-151 ybdN
MFNHADDB_03455 2.2e-213 ybdO S Domain of unknown function (DUF4885)
MFNHADDB_03456 5.8e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
MFNHADDB_03457 1.1e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
MFNHADDB_03458 4.9e-30 ybxH S Family of unknown function (DUF5370)
MFNHADDB_03459 3e-150 ybxI 3.5.2.6 V beta-lactamase
MFNHADDB_03460 4.3e-244 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
MFNHADDB_03461 4.9e-41 ybyB
MFNHADDB_03462 8.9e-290 ybeC E amino acid
MFNHADDB_03463 5.3e-164 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MFNHADDB_03464 7.3e-258 glpT G -transporter
MFNHADDB_03465 8.5e-35 S Protein of unknown function (DUF2651)
MFNHADDB_03466 1.4e-170 ybfA 3.4.15.5 K FR47-like protein
MFNHADDB_03467 1.9e-223 ybfB G COG0477 Permeases of the major facilitator superfamily
MFNHADDB_03469 0.0 ybfG M Domain of unknown function (DUF1906)
MFNHADDB_03470 8.8e-162 ybfH EG EamA-like transporter family
MFNHADDB_03471 2.3e-145 msmR K AraC-like ligand binding domain
MFNHADDB_03472 6.2e-213 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MFNHADDB_03473 1.7e-176 mpr 3.4.21.19 M Belongs to the peptidase S1B family
MFNHADDB_03475 3.7e-165 S Alpha/beta hydrolase family
MFNHADDB_03476 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MFNHADDB_03477 2.7e-85 ybfM S SNARE associated Golgi protein
MFNHADDB_03478 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MFNHADDB_03479 4.6e-45 ybfN
MFNHADDB_03480 9.5e-191 yceA S Belongs to the UPF0176 family
MFNHADDB_03481 6.4e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MFNHADDB_03482 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MFNHADDB_03483 2.1e-137 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MFNHADDB_03484 4.9e-128 K UTRA
MFNHADDB_03486 5.4e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MFNHADDB_03487 6.3e-260 mmuP E amino acid
MFNHADDB_03488 1.3e-179 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
MFNHADDB_03489 5.3e-254 agcS E Sodium alanine symporter
MFNHADDB_03490 1.5e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
MFNHADDB_03491 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
MFNHADDB_03492 9e-170 glnL T Regulator
MFNHADDB_03493 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
MFNHADDB_03494 3.7e-274 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MFNHADDB_03495 1.6e-255 gudP G COG0477 Permeases of the major facilitator superfamily
MFNHADDB_03496 3.6e-268 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MFNHADDB_03497 2.1e-123 ycbG K FCD
MFNHADDB_03498 1e-295 garD 4.2.1.42, 4.2.1.7 G Altronate
MFNHADDB_03499 4.4e-177 ycbJ S Macrolide 2'-phosphotransferase
MFNHADDB_03500 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
MFNHADDB_03501 2.9e-102 eamA1 EG spore germination
MFNHADDB_03502 7.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFNHADDB_03503 3.8e-168 T PhoQ Sensor
MFNHADDB_03504 2.2e-165 ycbN V ABC transporter, ATP-binding protein
MFNHADDB_03505 2.5e-113 S ABC-2 family transporter protein
MFNHADDB_03506 4.1e-52 ycbP S Protein of unknown function (DUF2512)
MFNHADDB_03507 1.3e-78 sleB 3.5.1.28 M Cell wall
MFNHADDB_03508 9.5e-135 ycbR T vWA found in TerF C terminus
MFNHADDB_03509 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
MFNHADDB_03510 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MFNHADDB_03511 1.2e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MFNHADDB_03512 2.9e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MFNHADDB_03513 1.1e-201 ycbU E Selenocysteine lyase
MFNHADDB_03514 3e-225 lmrB EGP the major facilitator superfamily
MFNHADDB_03515 1.4e-101 yxaF K Transcriptional regulator
MFNHADDB_03516 8.2e-202 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MFNHADDB_03517 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
MFNHADDB_03518 4.6e-56 S RDD family
MFNHADDB_03519 3.6e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
MFNHADDB_03520 5.2e-157 2.7.13.3 T GHKL domain
MFNHADDB_03521 1.2e-126 lytR_2 T LytTr DNA-binding domain
MFNHADDB_03522 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
MFNHADDB_03523 2.2e-202 natB CP ABC-2 family transporter protein
MFNHADDB_03524 1e-173 yccK C Aldo keto reductase
MFNHADDB_03525 6.6e-177 ycdA S Domain of unknown function (DUF5105)
MFNHADDB_03526 1.6e-271 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
MFNHADDB_03527 3.1e-257 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
MFNHADDB_03528 7.3e-94 cwlK M D-alanyl-D-alanine carboxypeptidase
MFNHADDB_03529 1.2e-173 S response regulator aspartate phosphatase
MFNHADDB_03530 1.8e-139 IQ Enoyl-(Acyl carrier protein) reductase
MFNHADDB_03531 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
MFNHADDB_03532 2.1e-166 adcA P Belongs to the bacterial solute-binding protein 9 family
MFNHADDB_03533 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MFNHADDB_03534 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MFNHADDB_03535 1.4e-184 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MFNHADDB_03536 1.6e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
MFNHADDB_03537 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
MFNHADDB_03538 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
MFNHADDB_03539 1.4e-136 terC P Protein of unknown function (DUF475)
MFNHADDB_03540 0.0 yceG S Putative component of 'biosynthetic module'
MFNHADDB_03541 2e-192 yceH P Belongs to the TelA family
MFNHADDB_03542 8.7e-218 naiP P Uncharacterised MFS-type transporter YbfB
MFNHADDB_03543 5.7e-206 yceJ EGP Uncharacterised MFS-type transporter YbfB
MFNHADDB_03544 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
MFNHADDB_03545 2.2e-227 proV 3.6.3.32 E glycine betaine
MFNHADDB_03546 1.3e-127 opuAB P glycine betaine
MFNHADDB_03547 5.3e-164 opuAC E glycine betaine
MFNHADDB_03548 4.1e-217 amhX S amidohydrolase
MFNHADDB_03549 5.6e-256 ycgA S Membrane
MFNHADDB_03550 4.1e-81 ycgB
MFNHADDB_03551 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
MFNHADDB_03552 1.2e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MFNHADDB_03553 6.5e-293 lctP C L-lactate permease
MFNHADDB_03554 6.2e-269 mdr EGP Major facilitator Superfamily
MFNHADDB_03555 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
MFNHADDB_03556 6.8e-113 ycgF E Lysine exporter protein LysE YggA
MFNHADDB_03557 1.2e-151 yqcI S YqcI/YcgG family
MFNHADDB_03558 1.6e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
MFNHADDB_03559 2.4e-112 ycgI S Domain of unknown function (DUF1989)
MFNHADDB_03560 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MFNHADDB_03561 2.1e-108 tmrB S AAA domain
MFNHADDB_03562 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MFNHADDB_03563 1.7e-142 yafE Q ubiE/COQ5 methyltransferase family
MFNHADDB_03564 1e-176 oxyR3 K LysR substrate binding domain
MFNHADDB_03565 9.4e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
MFNHADDB_03566 4.1e-144 ycgL S Predicted nucleotidyltransferase
MFNHADDB_03567 1.9e-169 ycgM E Proline dehydrogenase
MFNHADDB_03568 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MFNHADDB_03569 2e-247 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MFNHADDB_03570 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
MFNHADDB_03571 9.1e-145 ycgQ S membrane
MFNHADDB_03572 9.1e-140 ycgR S permeases
MFNHADDB_03573 1.6e-157 I alpha/beta hydrolase fold
MFNHADDB_03574 4e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MFNHADDB_03575 3e-273 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MFNHADDB_03576 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
MFNHADDB_03577 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MFNHADDB_03578 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MFNHADDB_03579 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
MFNHADDB_03580 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
MFNHADDB_03581 2.4e-167 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
MFNHADDB_03582 2.7e-108 yciB M ErfK YbiS YcfS YnhG
MFNHADDB_03583 1e-226 yciC S GTPases (G3E family)
MFNHADDB_03584 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
MFNHADDB_03585 9.9e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
MFNHADDB_03588 1.4e-72 yckC S membrane
MFNHADDB_03589 7.8e-52 yckD S Protein of unknown function (DUF2680)
MFNHADDB_03590 2.7e-287 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MFNHADDB_03591 6.5e-69 nin S Competence protein J (ComJ)
MFNHADDB_03592 3e-70 nucA M Deoxyribonuclease NucA/NucB
MFNHADDB_03593 3.9e-187 tlpC 2.7.13.3 NT chemotaxis protein
MFNHADDB_03594 1.8e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
MFNHADDB_03595 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
MFNHADDB_03596 1.3e-63 hxlR K transcriptional
MFNHADDB_03597 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFNHADDB_03598 9e-92 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFNHADDB_03600 4.5e-97 L endonuclease activity
MFNHADDB_03601 1.3e-48
MFNHADDB_03602 9.7e-211 S Tetratricopeptide repeat
MFNHADDB_03604 2.7e-126 yeeN K transcriptional regulatory protein
MFNHADDB_03606 8e-100 dhaR3 K Transcriptional regulator
MFNHADDB_03607 1.1e-77 yesE S SnoaL-like domain
MFNHADDB_03608 5.5e-150 yesF GM NAD(P)H-binding
MFNHADDB_03609 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
MFNHADDB_03610 1.5e-45 cotJB S CotJB protein
MFNHADDB_03611 5.2e-104 cotJC P Spore Coat
MFNHADDB_03612 3e-101 yesJ K Acetyltransferase (GNAT) family
MFNHADDB_03613 1.5e-101 yesL S Protein of unknown function, DUF624
MFNHADDB_03614 0.0 yesM 2.7.13.3 T Histidine kinase
MFNHADDB_03615 8e-202 yesN K helix_turn_helix, arabinose operon control protein
MFNHADDB_03616 2.8e-246 yesO G Bacterial extracellular solute-binding protein
MFNHADDB_03617 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
MFNHADDB_03618 1.2e-163 yesQ P Binding-protein-dependent transport system inner membrane component
MFNHADDB_03619 7.8e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
MFNHADDB_03620 0.0 yesS K Transcriptional regulator
MFNHADDB_03621 1.2e-131 E GDSL-like Lipase/Acylhydrolase
MFNHADDB_03622 5.1e-127 yesU S Domain of unknown function (DUF1961)
MFNHADDB_03623 1e-113 yesV S Protein of unknown function, DUF624
MFNHADDB_03624 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
MFNHADDB_03625 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
MFNHADDB_03626 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
MFNHADDB_03627 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
MFNHADDB_03628 0.0 yetA
MFNHADDB_03629 4e-289 lplA G Bacterial extracellular solute-binding protein
MFNHADDB_03630 5.5e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
MFNHADDB_03631 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
MFNHADDB_03632 1.2e-252 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
MFNHADDB_03633 8.8e-122 yetF S membrane
MFNHADDB_03634 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
MFNHADDB_03635 2.6e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MFNHADDB_03636 2.2e-34
MFNHADDB_03637 2.4e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MFNHADDB_03638 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
MFNHADDB_03639 4.5e-104 yetJ S Belongs to the BI1 family
MFNHADDB_03640 1.4e-89 yetL K helix_turn_helix multiple antibiotic resistance protein
MFNHADDB_03641 4e-209 yetM CH FAD binding domain
MFNHADDB_03642 1.7e-133 M Membrane
MFNHADDB_03643 3.7e-196 yetN S Protein of unknown function (DUF3900)
MFNHADDB_03644 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
MFNHADDB_03645 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MFNHADDB_03646 1.1e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
MFNHADDB_03647 3.2e-172 yfnG 4.2.1.45 M dehydratase
MFNHADDB_03648 1.1e-180 yfnF M Nucleotide-diphospho-sugar transferase
MFNHADDB_03649 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
MFNHADDB_03650 3.5e-190 yfnD M Nucleotide-diphospho-sugar transferase
MFNHADDB_03651 2e-206 fsr P COG0477 Permeases of the major facilitator superfamily
MFNHADDB_03652 7.8e-134 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MFNHADDB_03653 6.4e-241 yfnA E amino acid
MFNHADDB_03654 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MFNHADDB_03655 1.1e-113 yfmS NT chemotaxis protein
MFNHADDB_03656 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MFNHADDB_03657 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
MFNHADDB_03658 2.8e-70 yfmP K transcriptional
MFNHADDB_03659 4.3e-209 yfmO EGP Major facilitator Superfamily
MFNHADDB_03660 7.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MFNHADDB_03661 2.9e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
MFNHADDB_03662 3.1e-80 yfmK 2.3.1.128 K acetyltransferase
MFNHADDB_03663 9.4e-189 yfmJ S N-terminal domain of oxidoreductase
MFNHADDB_03664 7.7e-214 G Major Facilitator Superfamily
MFNHADDB_03665 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
MFNHADDB_03666 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
MFNHADDB_03667 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFNHADDB_03668 1.6e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFNHADDB_03669 3.4e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MFNHADDB_03670 5e-24 S Protein of unknown function (DUF3212)
MFNHADDB_03671 7.6e-58 yflT S Heat induced stress protein YflT
MFNHADDB_03672 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
MFNHADDB_03673 5.6e-235 yflS P Sodium:sulfate symporter transmembrane region
MFNHADDB_03674 4.1e-287 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MFNHADDB_03675 1.3e-117 citT T response regulator
MFNHADDB_03676 1.1e-178 yflP S Tripartite tricarboxylate transporter family receptor
MFNHADDB_03677 8.5e-227 citM C Citrate transporter
MFNHADDB_03678 3.9e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
MFNHADDB_03679 8.7e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MFNHADDB_03680 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MFNHADDB_03681 3.2e-121 yflK S protein conserved in bacteria
MFNHADDB_03682 4e-18 yflJ S Protein of unknown function (DUF2639)
MFNHADDB_03683 1.6e-18 yflI
MFNHADDB_03684 5.3e-50 yflH S Protein of unknown function (DUF3243)
MFNHADDB_03685 4.2e-138 map 3.4.11.18 E Methionine aminopeptidase
MFNHADDB_03686 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MFNHADDB_03687 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MFNHADDB_03688 6e-67 yhdN S Domain of unknown function (DUF1992)
MFNHADDB_03689 3.1e-251 agcS_1 E Sodium alanine symporter
MFNHADDB_03690 1.3e-193 E Spore germination protein
MFNHADDB_03692 5.1e-207 yfkR S spore germination
MFNHADDB_03693 1.5e-283 yfkQ EG Spore germination protein
MFNHADDB_03694 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MFNHADDB_03695 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MFNHADDB_03696 1.8e-133 treR K transcriptional
MFNHADDB_03697 1.8e-124 yfkO C nitroreductase
MFNHADDB_03698 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MFNHADDB_03699 9.6e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
MFNHADDB_03700 6.8e-207 ydiM EGP Major facilitator Superfamily
MFNHADDB_03701 1.3e-28 yfkK S Belongs to the UPF0435 family
MFNHADDB_03702 1.2e-82 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MFNHADDB_03703 2.4e-50 yfkI S gas vesicle protein
MFNHADDB_03704 9.7e-144 yihY S Belongs to the UPF0761 family
MFNHADDB_03705 5e-08
MFNHADDB_03706 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
MFNHADDB_03707 6.1e-183 cax P COG0387 Ca2 H antiporter
MFNHADDB_03708 1.2e-146 yfkD S YfkD-like protein
MFNHADDB_03709 6e-149 yfkC M Mechanosensitive ion channel
MFNHADDB_03710 5.4e-222 yfkA S YfkB-like domain
MFNHADDB_03711 1.1e-26 yfjT
MFNHADDB_03712 2.6e-154 pdaA G deacetylase
MFNHADDB_03713 4.2e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MFNHADDB_03714 1.7e-184 corA P Mediates influx of magnesium ions
MFNHADDB_03715 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MFNHADDB_03716 2.6e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MFNHADDB_03717 1.7e-42 S YfzA-like protein
MFNHADDB_03718 5.1e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MFNHADDB_03719 3.9e-86 yfjM S Psort location Cytoplasmic, score
MFNHADDB_03720 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MFNHADDB_03721 2.8e-188 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MFNHADDB_03722 4.2e-196 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MFNHADDB_03723 7.3e-253 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MFNHADDB_03724 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
MFNHADDB_03725 1.2e-25 sspH S Belongs to the SspH family
MFNHADDB_03726 4e-56 yfjF S UPF0060 membrane protein
MFNHADDB_03727 3.2e-79 S Family of unknown function (DUF5381)
MFNHADDB_03728 6.9e-101 yfjD S Family of unknown function (DUF5381)
MFNHADDB_03729 4.1e-144 yfjC
MFNHADDB_03730 9.2e-191 yfjB
MFNHADDB_03731 2.8e-43 yfjA S Belongs to the WXG100 family
MFNHADDB_03732 1.9e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MFNHADDB_03733 2.7e-140 glvR K Helix-turn-helix domain, rpiR family
MFNHADDB_03734 1e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MFNHADDB_03735 6.8e-309 yfiB3 V ABC transporter
MFNHADDB_03736 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
MFNHADDB_03737 6.4e-64 mhqP S DoxX
MFNHADDB_03738 3.7e-162 yfiE 1.13.11.2 S glyoxalase
MFNHADDB_03740 3.4e-211 yxjM T Histidine kinase
MFNHADDB_03741 4.6e-112 KT LuxR family transcriptional regulator
MFNHADDB_03742 3.2e-167 V ABC transporter, ATP-binding protein
MFNHADDB_03743 7.3e-209 V ABC-2 family transporter protein
MFNHADDB_03744 6.9e-204 V COG0842 ABC-type multidrug transport system, permease component
MFNHADDB_03745 4.1e-98 padR K transcriptional
MFNHADDB_03746 3.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
MFNHADDB_03747 1e-196 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MFNHADDB_03748 1.2e-99 yfiT S Belongs to the metal hydrolase YfiT family
MFNHADDB_03749 3.8e-282 yfiU EGP Major facilitator Superfamily
MFNHADDB_03750 4.9e-79 yfiV K transcriptional
MFNHADDB_03751 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MFNHADDB_03752 8.2e-174 yfiY P ABC transporter substrate-binding protein
MFNHADDB_03753 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFNHADDB_03754 6.8e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFNHADDB_03755 1.8e-167 yfhB 5.3.3.17 S PhzF family
MFNHADDB_03756 3.9e-107 yfhC C nitroreductase
MFNHADDB_03757 2.1e-25 yfhD S YfhD-like protein
MFNHADDB_03759 3.5e-171 yfhF S nucleoside-diphosphate sugar epimerase
MFNHADDB_03760 2.5e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
MFNHADDB_03761 3.2e-50 yfhH S Protein of unknown function (DUF1811)
MFNHADDB_03762 1.5e-209 yfhI EGP Major facilitator Superfamily
MFNHADDB_03763 6.2e-20 sspK S reproduction
MFNHADDB_03764 1.3e-44 yfhJ S WVELL protein
MFNHADDB_03765 5.1e-90 batE T Bacterial SH3 domain homologues
MFNHADDB_03766 3e-47 yfhL S SdpI/YhfL protein family
MFNHADDB_03767 4.4e-171 yfhM S Alpha beta hydrolase
MFNHADDB_03768 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MFNHADDB_03769 0.0 yfhO S Bacterial membrane protein YfhO
MFNHADDB_03770 5.5e-186 yfhP S membrane-bound metal-dependent
MFNHADDB_03771 1e-211 mutY L A G-specific
MFNHADDB_03772 6.9e-36 yfhS
MFNHADDB_03773 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFNHADDB_03774 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
MFNHADDB_03775 1.5e-37 ygaB S YgaB-like protein
MFNHADDB_03776 1.3e-104 ygaC J Belongs to the UPF0374 family
MFNHADDB_03777 1.8e-301 ygaD V ABC transporter
MFNHADDB_03778 8.7e-180 ygaE S Membrane
MFNHADDB_03779 1.4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MFNHADDB_03780 8.2e-87 bcp 1.11.1.15 O Peroxiredoxin
MFNHADDB_03781 4e-80 perR P Belongs to the Fur family
MFNHADDB_03782 9.5e-56 ygzB S UPF0295 protein
MFNHADDB_03783 6.7e-167 ygxA S Nucleotidyltransferase-like
MFNHADDB_03784 3e-42 S Domain of unknown function (DUF4652)
MFNHADDB_03785 5.2e-14 S Restriction endonuclease
MFNHADDB_03787 1.8e-29 ndoA L Toxic component of a toxin-antitoxin (TA) module
MFNHADDB_03789 1.2e-90 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MFNHADDB_03790 7.4e-11 K Cro/C1-type HTH DNA-binding domain
MFNHADDB_03792 4.9e-31 S Macro domain
MFNHADDB_03802 1.6e-29 sspB S spore protein
MFNHADDB_03806 7e-36
MFNHADDB_03808 2.4e-31 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MFNHADDB_03809 1.1e-161 S Thymidylate synthase
MFNHADDB_03813 2.4e-14 V COG4767 Glycopeptide antibiotics resistance protein
MFNHADDB_03814 5e-75 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
MFNHADDB_03815 1.5e-36 O Glutaredoxin
MFNHADDB_03816 2.6e-86 L HNH endonuclease
MFNHADDB_03817 6.3e-105 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MFNHADDB_03819 3.3e-202 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MFNHADDB_03820 3.4e-31 L GIY-YIG catalytic domain
MFNHADDB_03821 2.2e-115 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MFNHADDB_03822 3.4e-62 S NrdI Flavodoxin like
MFNHADDB_03826 5.1e-12 larC 4.99.1.12 FJ Protein conserved in bacteria
MFNHADDB_03835 3.6e-12
MFNHADDB_03841 2.4e-77 yhdJ 2.1.1.72 L DNA methylase
MFNHADDB_03842 8.7e-90 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
MFNHADDB_03843 1.4e-84 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
MFNHADDB_03848 8e-110 DR0488 S protein conserved in bacteria
MFNHADDB_03849 0.0 S Bacterial DNA polymerase III alpha subunit
MFNHADDB_03850 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MFNHADDB_03851 7.2e-222 L DNA primase activity
MFNHADDB_03852 3.6e-285 3.6.4.12 J DnaB-like helicase C terminal domain
MFNHADDB_03853 2.6e-85
MFNHADDB_03854 7.6e-180 L AAA domain
MFNHADDB_03855 3.1e-167
MFNHADDB_03859 0.0 M Parallel beta-helix repeats
MFNHADDB_03860 2.3e-137 S Pfam:DUF867
MFNHADDB_03862 2.2e-20 S YopX protein
MFNHADDB_03864 5.5e-129 yoqW S Belongs to the SOS response-associated peptidase family
MFNHADDB_03865 6.4e-148 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
MFNHADDB_03870 4.3e-73
MFNHADDB_03873 1.1e-41
MFNHADDB_03878 8.8e-12 S Protein of unknown function (DUF2815)
MFNHADDB_03879 2.7e-66 2.1.1.294, 2.7.1.181 N bacterial-type flagellum assembly
MFNHADDB_03884 5.3e-17
MFNHADDB_03890 1.1e-33 K Transcriptional regulator
MFNHADDB_03891 1.8e-176
MFNHADDB_03892 6e-263 S DNA-sulfur modification-associated
MFNHADDB_03893 8.9e-198 L Belongs to the 'phage' integrase family
MFNHADDB_03898 6.6e-106
MFNHADDB_03901 7.9e-41 smuG L deaminated base DNA N-glycosylase activity
MFNHADDB_03906 4.6e-11 ywlA S Uncharacterised protein family (UPF0715)
MFNHADDB_03910 7.5e-16 K Cro/C1-type HTH DNA-binding domain
MFNHADDB_03911 6.2e-81 yoaW
MFNHADDB_03912 1.2e-07 ywlA S Uncharacterised protein family (UPF0715)
MFNHADDB_03913 8.4e-75
MFNHADDB_03919 2.3e-202
MFNHADDB_03922 0.0
MFNHADDB_03923 9.4e-35 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MFNHADDB_03924 6.1e-198
MFNHADDB_03927 1.2e-200 S Calcineurin-like phosphoesterase superfamily domain
MFNHADDB_03929 1.3e-68
MFNHADDB_03930 5.1e-174
MFNHADDB_03931 1.9e-278
MFNHADDB_03932 3.2e-243
MFNHADDB_03933 7.8e-94
MFNHADDB_03934 2.8e-185
MFNHADDB_03935 1.1e-80
MFNHADDB_03936 7.9e-67
MFNHADDB_03938 7e-121
MFNHADDB_03939 8.8e-79
MFNHADDB_03940 1e-72
MFNHADDB_03941 3.2e-59
MFNHADDB_03944 1.9e-51
MFNHADDB_03945 1.8e-29
MFNHADDB_03948 1.8e-84
MFNHADDB_03949 6.7e-64
MFNHADDB_03950 1.2e-191 xerH A Belongs to the 'phage' integrase family
MFNHADDB_03951 2e-39 K Helix-turn-helix
MFNHADDB_03952 2.9e-47
MFNHADDB_03953 0.0 S peptidoglycan catabolic process
MFNHADDB_03954 3.8e-83 S Phage tail protein
MFNHADDB_03955 1.5e-302 S Pfam Transposase IS66
MFNHADDB_03956 9.5e-99
MFNHADDB_03957 6e-55 S outer membrane
MFNHADDB_03958 9.2e-78 S N-acetylmuramoyl-L-alanine amidase activity
MFNHADDB_03960 3.5e-36 S Bacteriophage holin
MFNHADDB_03961 6.4e-93 S response regulator aspartate phosphatase
MFNHADDB_03963 4.8e-43 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MFNHADDB_03964 1.7e-21 Q Methyltransferase
MFNHADDB_03965 2.7e-35 2.7.7.73, 2.7.7.80 H ThiF family
MFNHADDB_03966 2e-32 Q Methyltransferase domain
MFNHADDB_03967 5.5e-26 G Major Facilitator Superfamily
MFNHADDB_03968 1.4e-231 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MFNHADDB_03969 1.7e-51 S YolD-like protein
MFNHADDB_03971 1.3e-37
MFNHADDB_03973 2.6e-08 S Domain of unknown function (DUF4879)
MFNHADDB_03975 6.8e-98 J Acetyltransferase (GNAT) domain
MFNHADDB_03976 1.3e-99 yokK S SMI1 / KNR4 family
MFNHADDB_03977 6.7e-86 S SMI1-KNR4 cell-wall
MFNHADDB_03978 5.4e-36 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MFNHADDB_03979 1.9e-230 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MFNHADDB_03980 1.6e-132 V HNH endonuclease
MFNHADDB_03981 6.9e-66 G SMI1-KNR4 cell-wall
MFNHADDB_03982 2.3e-106 yokF 3.1.31.1 L RNA catabolic process
MFNHADDB_03983 6.4e-80 yhbS S family acetyltransferase
MFNHADDB_03984 1.7e-261 S Recombinase
MFNHADDB_03985 7.8e-08
MFNHADDB_03987 9e-181 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MFNHADDB_03988 2.6e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
MFNHADDB_03989 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
MFNHADDB_03990 3.1e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MFNHADDB_03991 3.9e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MFNHADDB_03992 0.0 ydiF S ABC transporter
MFNHADDB_03993 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MFNHADDB_03994 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MFNHADDB_03995 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MFNHADDB_03996 1.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MFNHADDB_03997 2.9e-27 ydiK S Domain of unknown function (DUF4305)
MFNHADDB_03998 7.9e-129 ydiL S CAAX protease self-immunity
MFNHADDB_03999 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MFNHADDB_04000 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MFNHADDB_04001 6.8e-152 ydjC S Abhydrolase domain containing 18
MFNHADDB_04002 0.0 K NB-ARC domain
MFNHADDB_04003 8.5e-201 gutB 1.1.1.14 E Dehydrogenase
MFNHADDB_04004 6.7e-254 gutA G MFS/sugar transport protein
MFNHADDB_04005 7.5e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
MFNHADDB_04006 1.3e-112 pspA KT Phage shock protein A
MFNHADDB_04007 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MFNHADDB_04008 3.4e-135 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
MFNHADDB_04009 4.1e-149 ydjI S virion core protein (lumpy skin disease virus)
MFNHADDB_04010 4.8e-193 S Ion transport 2 domain protein
MFNHADDB_04011 3.9e-257 iolT EGP Major facilitator Superfamily
MFNHADDB_04012 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
MFNHADDB_04013 4.5e-64 ydjM M Lytic transglycolase
MFNHADDB_04014 1.8e-155 ydjN U Involved in the tonB-independent uptake of proteins
MFNHADDB_04016 1.4e-34 ydjO S Cold-inducible protein YdjO
MFNHADDB_04017 2e-157 ydjP I Alpha/beta hydrolase family
MFNHADDB_04018 3.7e-174 yeaA S Protein of unknown function (DUF4003)
MFNHADDB_04019 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
MFNHADDB_04020 4.4e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
MFNHADDB_04021 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MFNHADDB_04022 1.7e-176 yeaC S COG0714 MoxR-like ATPases
MFNHADDB_04023 1.4e-223 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MFNHADDB_04024 0.0 yebA E COG1305 Transglutaminase-like enzymes
MFNHADDB_04025 3.7e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MFNHADDB_04026 6.6e-211 pbuG S permease
MFNHADDB_04027 4.4e-117 yebC M Membrane
MFNHADDB_04029 8.9e-93 yebE S UPF0316 protein
MFNHADDB_04030 8e-28 yebG S NETI protein
MFNHADDB_04031 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MFNHADDB_04032 8.5e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MFNHADDB_04033 6.2e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MFNHADDB_04034 4.9e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MFNHADDB_04035 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MFNHADDB_04036 8.6e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MFNHADDB_04037 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MFNHADDB_04038 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MFNHADDB_04039 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MFNHADDB_04040 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MFNHADDB_04041 1.2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MFNHADDB_04042 1e-232 purD 6.3.4.13 F Belongs to the GARS family
MFNHADDB_04043 1.1e-71 K helix_turn_helix ASNC type
MFNHADDB_04044 1.9e-231 yjeH E Amino acid permease
MFNHADDB_04045 2.7e-27 S Protein of unknown function (DUF2892)
MFNHADDB_04046 0.0 yerA 3.5.4.2 F adenine deaminase
MFNHADDB_04047 3e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
MFNHADDB_04048 4.8e-51 yerC S protein conserved in bacteria
MFNHADDB_04049 3.2e-305 yerD 1.4.7.1 E Belongs to the glutamate synthase family
MFNHADDB_04051 8.4e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MFNHADDB_04052 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MFNHADDB_04053 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MFNHADDB_04054 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
MFNHADDB_04055 9.2e-197 yerI S homoserine kinase type II (protein kinase fold)
MFNHADDB_04056 1.6e-123 sapB S MgtC SapB transporter
MFNHADDB_04057 3.2e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MFNHADDB_04058 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MFNHADDB_04059 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MFNHADDB_04060 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MFNHADDB_04061 5.1e-148 yerO K Transcriptional regulator
MFNHADDB_04062 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MFNHADDB_04063 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MFNHADDB_04064 4.1e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MFNHADDB_04065 6.1e-55 S 37-kD nucleoid-associated bacterial protein
MFNHADDB_04066 3.4e-52
MFNHADDB_04067 3.8e-29
MFNHADDB_04068 3.3e-83 S Protein of unknown function, DUF600
MFNHADDB_04069 0.0 L nucleic acid phosphodiester bond hydrolysis
MFNHADDB_04070 2.9e-76 ctsR K Belongs to the CtsR family
MFNHADDB_04071 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
MFNHADDB_04072 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MFNHADDB_04073 0.0 clpC O Belongs to the ClpA ClpB family
MFNHADDB_04074 6.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MFNHADDB_04075 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MFNHADDB_04076 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
MFNHADDB_04077 7.2e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MFNHADDB_04078 1.2e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MFNHADDB_04079 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MFNHADDB_04080 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
MFNHADDB_04081 9.3e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MFNHADDB_04082 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MFNHADDB_04083 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MFNHADDB_04084 1.2e-88 yacP S RNA-binding protein containing a PIN domain
MFNHADDB_04085 4.4e-115 sigH K Belongs to the sigma-70 factor family
MFNHADDB_04086 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MFNHADDB_04087 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
MFNHADDB_04088 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MFNHADDB_04089 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MFNHADDB_04090 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MFNHADDB_04091 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MFNHADDB_04092 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
MFNHADDB_04093 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MFNHADDB_04094 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MFNHADDB_04095 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
MFNHADDB_04096 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MFNHADDB_04097 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MFNHADDB_04098 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MFNHADDB_04099 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MFNHADDB_04100 3.1e-178 ybaC 3.4.11.5 S Alpha/beta hydrolase family
MFNHADDB_04101 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MFNHADDB_04102 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MFNHADDB_04103 3.9e-105 rplD J Forms part of the polypeptide exit tunnel
MFNHADDB_04104 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MFNHADDB_04105 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MFNHADDB_04106 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MFNHADDB_04107 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MFNHADDB_04108 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MFNHADDB_04109 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MFNHADDB_04110 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
MFNHADDB_04111 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MFNHADDB_04112 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MFNHADDB_04113 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MFNHADDB_04114 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MFNHADDB_04115 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MFNHADDB_04116 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MFNHADDB_04117 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MFNHADDB_04118 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MFNHADDB_04119 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MFNHADDB_04120 1.9e-23 rpmD J Ribosomal protein L30
MFNHADDB_04121 1.8e-72 rplO J binds to the 23S rRNA
MFNHADDB_04122 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MFNHADDB_04123 4.8e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MFNHADDB_04124 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
MFNHADDB_04125 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MFNHADDB_04126 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MFNHADDB_04127 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MFNHADDB_04128 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MFNHADDB_04129 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MFNHADDB_04130 3.6e-58 rplQ J Ribosomal protein L17
MFNHADDB_04131 7.3e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MFNHADDB_04132 2.4e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MFNHADDB_04133 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MFNHADDB_04134 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MFNHADDB_04135 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MFNHADDB_04136 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
MFNHADDB_04137 8.2e-145 ybaJ Q Methyltransferase domain
MFNHADDB_04138 9.7e-66 ybaK S Protein of unknown function (DUF2521)
MFNHADDB_04139 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MFNHADDB_04140 2e-197 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MFNHADDB_04141 1.2e-84 gerD
MFNHADDB_04142 3.9e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
MFNHADDB_04143 4.6e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
MFNHADDB_04144 1.4e-281 cisA2 L Recombinase
MFNHADDB_04145 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
MFNHADDB_04146 6e-183 arsB 1.20.4.1 P Arsenic resistance protein
MFNHADDB_04147 2.8e-73 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MFNHADDB_04148 1.6e-54 arsR K ArsR family transcriptional regulator
MFNHADDB_04149 1.1e-152 yqcI S YqcI/YcgG family
MFNHADDB_04150 2.8e-23 S YtkA-like
MFNHADDB_04151 5.5e-50 piuB S PepSY-associated TM region
MFNHADDB_04152 1.1e-113 piuB S PepSY-associated TM region
MFNHADDB_04153 2.7e-63 K BetI-type transcriptional repressor, C-terminal
MFNHADDB_04154 5.1e-139 yhfP 1.1.1.1 C Alcohol dehydrogenase GroES-like domain
MFNHADDB_04155 3.1e-44
MFNHADDB_04156 1.1e-40 S Protein of unknown function (DUF3992)
MFNHADDB_04157 5.1e-42 S Spore coat protein Z
MFNHADDB_04158 4.7e-64 S response regulator aspartate phosphatase
MFNHADDB_04160 1.7e-27
MFNHADDB_04161 3.3e-273 A Pre-toxin TG
MFNHADDB_04162 5.3e-104 S Suppressor of fused protein (SUFU)
MFNHADDB_04164 5e-60
MFNHADDB_04166 1.1e-144 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
MFNHADDB_04167 2.6e-68 S Bacteriophage holin family
MFNHADDB_04168 4.8e-165 xepA
MFNHADDB_04169 1.3e-23
MFNHADDB_04170 4.1e-56 xkdW S XkdW protein
MFNHADDB_04171 2e-221
MFNHADDB_04172 9.6e-40
MFNHADDB_04173 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
MFNHADDB_04174 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MFNHADDB_04175 9.6e-71 xkdS S Protein of unknown function (DUF2634)
MFNHADDB_04176 1.8e-38 xkdR S Protein of unknown function (DUF2577)
MFNHADDB_04177 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
MFNHADDB_04178 9e-114 xkdP S Lysin motif
MFNHADDB_04179 0.0 xkdO L Transglycosylase SLT domain
MFNHADDB_04180 1.8e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
MFNHADDB_04182 3.9e-75 xkdM S Phage tail tube protein
MFNHADDB_04183 2.8e-252 xkdK S Phage tail sheath C-terminal domain
MFNHADDB_04184 4.6e-25
MFNHADDB_04185 6.6e-75
MFNHADDB_04186 5.6e-86 S Bacteriophage HK97-gp10, putative tail-component
MFNHADDB_04187 6.3e-63 yqbH S Domain of unknown function (DUF3599)
MFNHADDB_04188 4.6e-67 S Protein of unknown function (DUF3199)
MFNHADDB_04189 6.7e-45 S YqbF, hypothetical protein domain
MFNHADDB_04190 4.6e-166 xkdG S Phage capsid family
MFNHADDB_04191 3.4e-119 yqbD 2.1.1.72 L Putative phage serine protease XkdF
MFNHADDB_04193 5e-149 S Phage Mu protein F like protein
MFNHADDB_04194 9.2e-289 yqbA S portal protein
MFNHADDB_04195 1.4e-248 S phage terminase, large subunit
MFNHADDB_04196 8.3e-99 yqaS L DNA packaging
MFNHADDB_04198 2.8e-89 yrdC 3.5.1.19 Q Isochorismatase family
MFNHADDB_04202 1.1e-48 wecC 1.1.1.336 M ArpU family transcriptional regulator
MFNHADDB_04204 8.9e-30 yqaO S Phage-like element PBSX protein XtrA
MFNHADDB_04205 2.6e-68 rusA L Endodeoxyribonuclease RusA
MFNHADDB_04207 4.4e-163 xkdC L IstB-like ATP binding protein
MFNHADDB_04208 4.4e-121 3.1.3.16 L DnaD domain protein
MFNHADDB_04209 1.7e-135 recT L RecT family
MFNHADDB_04210 9.5e-175 yqaJ L YqaJ-like viral recombinase domain
MFNHADDB_04214 4.9e-102
MFNHADDB_04216 5.9e-17 K Helix-turn-helix XRE-family like proteins
MFNHADDB_04217 1.1e-32 K sequence-specific DNA binding
MFNHADDB_04219 7.6e-97 adk 2.7.4.3 F adenylate kinase activity
MFNHADDB_04221 2.2e-93 yqaB E IrrE N-terminal-like domain
MFNHADDB_04222 8.4e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MFNHADDB_04223 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MFNHADDB_04224 4.1e-30 yazB K transcriptional
MFNHADDB_04225 6e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MFNHADDB_04226 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MFNHADDB_04227 8.5e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MFNHADDB_04228 2.3e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
MFNHADDB_04229 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
MFNHADDB_04230 3.1e-267 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MFNHADDB_04231 2.8e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MFNHADDB_04232 1.3e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
MFNHADDB_04233 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MFNHADDB_04234 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MFNHADDB_04235 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MFNHADDB_04236 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MFNHADDB_04237 3.5e-274 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MFNHADDB_04238 7.4e-186 KLT serine threonine protein kinase
MFNHADDB_04239 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
MFNHADDB_04240 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
MFNHADDB_04243 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
MFNHADDB_04244 1.1e-44 divIC D Septum formation initiator
MFNHADDB_04245 4.3e-107 yabQ S spore cortex biosynthesis protein
MFNHADDB_04246 1.5e-49 yabP S Sporulation protein YabP
MFNHADDB_04247 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MFNHADDB_04248 5.6e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MFNHADDB_04249 7.6e-286 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MFNHADDB_04250 1.5e-92 spoVT K stage V sporulation protein
MFNHADDB_04251 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MFNHADDB_04252 2.4e-39 yabK S Peptide ABC transporter permease
MFNHADDB_04253 1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MFNHADDB_04254 9.6e-96 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MFNHADDB_04255 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MFNHADDB_04256 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MFNHADDB_04257 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MFNHADDB_04258 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
MFNHADDB_04259 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MFNHADDB_04260 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MFNHADDB_04261 8.3e-27 sspF S DNA topological change
MFNHADDB_04262 7.8e-39 veg S protein conserved in bacteria
MFNHADDB_04263 1.8e-135 yabG S peptidase
MFNHADDB_04264 4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MFNHADDB_04265 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MFNHADDB_04266 5.8e-167 rpfB GH23 T protein conserved in bacteria
MFNHADDB_04267 4.5e-143 tatD L hydrolase, TatD
MFNHADDB_04268 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MFNHADDB_04269 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
MFNHADDB_04270 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MFNHADDB_04271 1.5e-49 yazA L endonuclease containing a URI domain
MFNHADDB_04272 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
MFNHADDB_04273 4.8e-31 yabA L Involved in initiation control of chromosome replication
MFNHADDB_04274 2.1e-146 yaaT S stage 0 sporulation protein
MFNHADDB_04275 2.2e-182 holB 2.7.7.7 L DNA polymerase III
MFNHADDB_04276 1.5e-71 yaaR S protein conserved in bacteria
MFNHADDB_04277 2.2e-54 yaaQ S protein conserved in bacteria
MFNHADDB_04278 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MFNHADDB_04279 1e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
MFNHADDB_04280 2.9e-202 yaaN P Belongs to the TelA family
MFNHADDB_04281 4.7e-103 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
MFNHADDB_04282 3.4e-31 csfB S Inhibitor of sigma-G Gin
MFNHADDB_04283 1.8e-35 bofA S Sigma-K factor-processing regulatory protein BofA
MFNHADDB_04284 7.9e-32 yaaL S Protein of unknown function (DUF2508)
MFNHADDB_04285 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MFNHADDB_04286 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MFNHADDB_04287 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MFNHADDB_04288 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MFNHADDB_04289 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
MFNHADDB_04290 1.2e-212 yaaH M Glycoside Hydrolase Family
MFNHADDB_04291 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
MFNHADDB_04292 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
MFNHADDB_04293 1.3e-09
MFNHADDB_04294 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MFNHADDB_04295 2.3e-107 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MFNHADDB_04296 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MFNHADDB_04297 6.8e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MFNHADDB_04298 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MFNHADDB_04299 8.7e-181 yaaC S YaaC-like Protein
MFNHADDB_04300 3.4e-39 S COG NOG14552 non supervised orthologous group
MFNHADDB_04305 2e-08
MFNHADDB_04314 7.8e-08
MFNHADDB_04316 2e-08
MFNHADDB_04322 1.6e-43 4.2.1.17 I enoyl-CoA hydratase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)