ORF_ID e_value Gene_name EC_number CAZy COGs Description
CGAIOGLK_00007 2e-08
CGAIOGLK_00011 1.9e-141 spo0M S COG4326 Sporulation control protein
CGAIOGLK_00012 3.3e-26
CGAIOGLK_00013 9.4e-132 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
CGAIOGLK_00014 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CGAIOGLK_00015 2.2e-262 ygaK C Berberine and berberine like
CGAIOGLK_00017 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
CGAIOGLK_00018 2.5e-138 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
CGAIOGLK_00019 4e-168 ssuA M Sulfonate ABC transporter
CGAIOGLK_00020 3.2e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
CGAIOGLK_00021 1.3e-215 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
CGAIOGLK_00023 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CGAIOGLK_00024 9.1e-78 ygaO
CGAIOGLK_00025 4.4e-29 K Transcriptional regulator
CGAIOGLK_00027 1.3e-111 yhzB S B3/4 domain
CGAIOGLK_00028 6e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CGAIOGLK_00029 4.4e-177 yhbB S Putative amidase domain
CGAIOGLK_00030 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CGAIOGLK_00031 1.8e-108 yhbD K Protein of unknown function (DUF4004)
CGAIOGLK_00032 2e-12 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
CGAIOGLK_00033 6.8e-45 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
CGAIOGLK_00034 1.6e-70 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
CGAIOGLK_00035 0.0 prkA T Ser protein kinase
CGAIOGLK_00036 2.5e-225 yhbH S Belongs to the UPF0229 family
CGAIOGLK_00037 2.2e-76 yhbI K DNA-binding transcription factor activity
CGAIOGLK_00038 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
CGAIOGLK_00039 6.9e-271 yhcA EGP Major facilitator Superfamily
CGAIOGLK_00040 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
CGAIOGLK_00041 2.8e-37 yhcC
CGAIOGLK_00042 4.6e-55
CGAIOGLK_00043 1.9e-59 yhcF K Transcriptional regulator
CGAIOGLK_00044 4e-122 yhcG V ABC transporter, ATP-binding protein
CGAIOGLK_00045 8.5e-165 yhcH V ABC transporter, ATP-binding protein
CGAIOGLK_00046 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
CGAIOGLK_00047 1e-30 cspB K Cold-shock protein
CGAIOGLK_00048 7.5e-152 metQ M Belongs to the nlpA lipoprotein family
CGAIOGLK_00049 1.3e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
CGAIOGLK_00050 1.8e-219 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CGAIOGLK_00051 6.2e-41 yhcM
CGAIOGLK_00052 6e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CGAIOGLK_00053 2.8e-166 yhcP
CGAIOGLK_00054 5.2e-100 yhcQ M Spore coat protein
CGAIOGLK_00055 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
CGAIOGLK_00056 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
CGAIOGLK_00057 2.3e-102 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
CGAIOGLK_00058 9.6e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CGAIOGLK_00059 9.3e-68 yhcU S Family of unknown function (DUF5365)
CGAIOGLK_00060 9.9e-68 yhcV S COG0517 FOG CBS domain
CGAIOGLK_00061 1.3e-119 yhcW 5.4.2.6 S hydrolase
CGAIOGLK_00062 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
CGAIOGLK_00063 1.2e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CGAIOGLK_00064 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CGAIOGLK_00065 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
CGAIOGLK_00066 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CGAIOGLK_00067 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CGAIOGLK_00068 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
CGAIOGLK_00069 5.5e-214 yhcY 2.7.13.3 T Histidine kinase
CGAIOGLK_00070 1.7e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CGAIOGLK_00071 7.2e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
CGAIOGLK_00072 1.2e-38 yhdB S YhdB-like protein
CGAIOGLK_00073 4.8e-54 yhdC S Protein of unknown function (DUF3889)
CGAIOGLK_00074 1.8e-188 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
CGAIOGLK_00075 1e-75 nsrR K Transcriptional regulator
CGAIOGLK_00076 1.5e-238 ygxB M Conserved TM helix
CGAIOGLK_00077 2.1e-276 ycgB S Stage V sporulation protein R
CGAIOGLK_00078 5.4e-256 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
CGAIOGLK_00079 1e-139 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
CGAIOGLK_00080 3.8e-162 citR K Transcriptional regulator
CGAIOGLK_00081 2.6e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
CGAIOGLK_00082 9.2e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CGAIOGLK_00083 1.7e-249 yhdG E amino acid
CGAIOGLK_00084 1.3e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
CGAIOGLK_00085 1e-270 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CGAIOGLK_00086 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CGAIOGLK_00087 8.1e-45 yhdK S Sigma-M inhibitor protein
CGAIOGLK_00088 6.6e-201 yhdL S Sigma factor regulator N-terminal
CGAIOGLK_00089 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
CGAIOGLK_00090 2.6e-191 yhdN C Aldo keto reductase
CGAIOGLK_00091 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
CGAIOGLK_00092 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
CGAIOGLK_00093 4.7e-74 cueR K transcriptional
CGAIOGLK_00094 4.4e-222 yhdR 2.6.1.1 E Aminotransferase
CGAIOGLK_00095 1.3e-238 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
CGAIOGLK_00096 1.3e-44 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CGAIOGLK_00097 9.6e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CGAIOGLK_00098 9.5e-135 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
CGAIOGLK_00100 5.6e-203 yhdY M Mechanosensitive ion channel
CGAIOGLK_00101 3.8e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
CGAIOGLK_00102 2.1e-149 yheN G deacetylase
CGAIOGLK_00103 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
CGAIOGLK_00104 1.5e-229 nhaC C Na H antiporter
CGAIOGLK_00105 1.4e-82 nhaX T Belongs to the universal stress protein A family
CGAIOGLK_00106 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
CGAIOGLK_00107 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
CGAIOGLK_00108 3.7e-111 yheG GM NAD(P)H-binding
CGAIOGLK_00109 6.3e-28 sspB S spore protein
CGAIOGLK_00110 1.3e-36 yheE S Family of unknown function (DUF5342)
CGAIOGLK_00111 4.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
CGAIOGLK_00112 4.3e-216 yheC HJ YheC/D like ATP-grasp
CGAIOGLK_00113 1.4e-201 yheB S Belongs to the UPF0754 family
CGAIOGLK_00114 9.5e-48 yheA S Belongs to the UPF0342 family
CGAIOGLK_00115 8.6e-201 yhaZ L DNA alkylation repair enzyme
CGAIOGLK_00116 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
CGAIOGLK_00117 1.8e-292 hemZ H coproporphyrinogen III oxidase
CGAIOGLK_00118 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
CGAIOGLK_00119 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
CGAIOGLK_00121 2.1e-132 yhaR 5.3.3.18 I enoyl-CoA hydratase
CGAIOGLK_00122 1.1e-26 S YhzD-like protein
CGAIOGLK_00123 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
CGAIOGLK_00124 2.7e-214 yhaP CP COG1668 ABC-type Na efflux pump, permease component
CGAIOGLK_00125 5e-221 yhaO L DNA repair exonuclease
CGAIOGLK_00126 0.0 yhaN L AAA domain
CGAIOGLK_00127 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
CGAIOGLK_00128 4.6e-21 yhaL S Sporulation protein YhaL
CGAIOGLK_00129 1.8e-111 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CGAIOGLK_00130 1.6e-88 yhaK S Putative zincin peptidase
CGAIOGLK_00131 1.3e-54 yhaI S Protein of unknown function (DUF1878)
CGAIOGLK_00132 1e-113 hpr K Negative regulator of protease production and sporulation
CGAIOGLK_00133 7e-39 yhaH S YtxH-like protein
CGAIOGLK_00134 3.6e-80 trpP S Tryptophan transporter TrpP
CGAIOGLK_00135 7.1e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CGAIOGLK_00136 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
CGAIOGLK_00137 4.6e-137 ecsA V transporter (ATP-binding protein)
CGAIOGLK_00138 1.6e-214 ecsB U ABC transporter
CGAIOGLK_00139 4.6e-110 ecsC S EcsC protein family
CGAIOGLK_00140 1.8e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
CGAIOGLK_00141 1.7e-233 yhfA C membrane
CGAIOGLK_00142 3.5e-33 1.15.1.2 C Rubrerythrin
CGAIOGLK_00143 1.9e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
CGAIOGLK_00144 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CGAIOGLK_00145 1.7e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CGAIOGLK_00146 3.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
CGAIOGLK_00147 9.1e-267 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CGAIOGLK_00148 5.4e-101 yhgD K Transcriptional regulator
CGAIOGLK_00149 4e-235 yhgE S YhgE Pip N-terminal domain protein
CGAIOGLK_00150 2.5e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CGAIOGLK_00151 1.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
CGAIOGLK_00152 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
CGAIOGLK_00153 3.7e-72 3.4.13.21 S ASCH
CGAIOGLK_00154 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CGAIOGLK_00155 5.2e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
CGAIOGLK_00156 2.4e-189 lplJ 6.3.1.20 H Lipoate-protein ligase
CGAIOGLK_00157 7.7e-112 yhfK GM NmrA-like family
CGAIOGLK_00158 7e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
CGAIOGLK_00159 1.9e-65 yhfM
CGAIOGLK_00160 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
CGAIOGLK_00161 4.7e-197 aprE 3.4.21.62 O Belongs to the peptidase S8 family
CGAIOGLK_00162 1.4e-75 VY92_01935 K acetyltransferase
CGAIOGLK_00163 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
CGAIOGLK_00164 4.3e-159 yfmC M Periplasmic binding protein
CGAIOGLK_00165 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
CGAIOGLK_00166 5.5e-195 vraB 2.3.1.9 I Belongs to the thiolase family
CGAIOGLK_00167 1.7e-273 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
CGAIOGLK_00168 5e-91 bioY S BioY family
CGAIOGLK_00169 1.7e-182 hemAT NT chemotaxis protein
CGAIOGLK_00170 2.6e-299 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
CGAIOGLK_00171 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CGAIOGLK_00172 1.3e-32 yhzC S IDEAL
CGAIOGLK_00173 4.2e-109 comK K Competence transcription factor
CGAIOGLK_00174 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
CGAIOGLK_00175 7.8e-42 yhjA S Excalibur calcium-binding domain
CGAIOGLK_00176 6.1e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGAIOGLK_00177 6.9e-27 yhjC S Protein of unknown function (DUF3311)
CGAIOGLK_00178 3.3e-59 yhjD
CGAIOGLK_00179 9.1e-110 yhjE S SNARE associated Golgi protein
CGAIOGLK_00180 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
CGAIOGLK_00181 4.5e-280 yhjG CH FAD binding domain
CGAIOGLK_00182 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
CGAIOGLK_00183 2e-214 glcP G Major Facilitator Superfamily
CGAIOGLK_00184 4.6e-199 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
CGAIOGLK_00185 9e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
CGAIOGLK_00186 7.3e-112 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
CGAIOGLK_00187 4.5e-129 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
CGAIOGLK_00188 1.3e-187 yhjM 5.1.1.1 K Transcriptional regulator
CGAIOGLK_00189 9.3e-201 abrB S membrane
CGAIOGLK_00190 4.2e-212 EGP Transmembrane secretion effector
CGAIOGLK_00191 0.0 S Sugar transport-related sRNA regulator N-term
CGAIOGLK_00192 2.2e-78 yhjR S Rubrerythrin
CGAIOGLK_00193 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
CGAIOGLK_00194 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
CGAIOGLK_00195 1.2e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
CGAIOGLK_00196 0.0 sbcC L COG0419 ATPase involved in DNA repair
CGAIOGLK_00197 4.3e-49 yisB V COG1403 Restriction endonuclease
CGAIOGLK_00198 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
CGAIOGLK_00199 2e-65 gerPE S Spore germination protein GerPE
CGAIOGLK_00200 6.3e-24 gerPD S Spore germination protein
CGAIOGLK_00201 1.8e-54 gerPC S Spore germination protein
CGAIOGLK_00202 4e-34 gerPB S cell differentiation
CGAIOGLK_00203 1.9e-33 gerPA S Spore germination protein
CGAIOGLK_00204 1.5e-22 yisI S Spo0E like sporulation regulatory protein
CGAIOGLK_00205 1.8e-170 cotH M Spore Coat
CGAIOGLK_00206 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
CGAIOGLK_00207 3.9e-57 yisL S UPF0344 protein
CGAIOGLK_00208 0.0 wprA O Belongs to the peptidase S8 family
CGAIOGLK_00209 2.1e-105 yisN S Protein of unknown function (DUF2777)
CGAIOGLK_00210 0.0 asnO 6.3.5.4 E Asparagine synthase
CGAIOGLK_00211 2.3e-87 yizA S Damage-inducible protein DinB
CGAIOGLK_00212 2.4e-147 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
CGAIOGLK_00213 3.4e-242 yisQ V Mate efflux family protein
CGAIOGLK_00214 2e-160 yisR K Transcriptional regulator
CGAIOGLK_00215 6.9e-184 purR K helix_turn _helix lactose operon repressor
CGAIOGLK_00216 3.7e-193 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
CGAIOGLK_00217 1.8e-92 yisT S DinB family
CGAIOGLK_00218 2.7e-106 argO S Lysine exporter protein LysE YggA
CGAIOGLK_00219 7.6e-277 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CGAIOGLK_00220 4e-36 mcbG S Pentapeptide repeats (9 copies)
CGAIOGLK_00221 4.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CGAIOGLK_00222 1.4e-112 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
CGAIOGLK_00223 7.9e-232 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
CGAIOGLK_00224 1.6e-139 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
CGAIOGLK_00225 1.3e-120 comB 3.1.3.71 H Belongs to the ComB family
CGAIOGLK_00226 1.6e-140 yitD 4.4.1.19 S synthase
CGAIOGLK_00227 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
CGAIOGLK_00228 3e-220 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
CGAIOGLK_00229 4e-229 yitG EGP Major facilitator Superfamily
CGAIOGLK_00230 9e-153 yitH K Acetyltransferase (GNAT) domain
CGAIOGLK_00231 1e-70 yjcF S Acetyltransferase (GNAT) domain
CGAIOGLK_00232 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
CGAIOGLK_00233 3.3e-54 yajQ S Belongs to the UPF0234 family
CGAIOGLK_00234 2.6e-160 cvfB S protein conserved in bacteria
CGAIOGLK_00235 8.5e-94
CGAIOGLK_00236 1.8e-170
CGAIOGLK_00237 1.5e-97 S Sporulation delaying protein SdpA
CGAIOGLK_00238 1.5e-58 K Transcriptional regulator PadR-like family
CGAIOGLK_00239 1e-94
CGAIOGLK_00240 1.4e-44 yitR S Domain of unknown function (DUF3784)
CGAIOGLK_00241 2.2e-309 nprB 3.4.24.28 E Peptidase M4
CGAIOGLK_00242 2.5e-158 yitS S protein conserved in bacteria
CGAIOGLK_00243 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
CGAIOGLK_00244 5e-73 ipi S Intracellular proteinase inhibitor
CGAIOGLK_00245 2.8e-17 S Protein of unknown function (DUF3813)
CGAIOGLK_00247 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
CGAIOGLK_00248 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
CGAIOGLK_00249 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
CGAIOGLK_00250 4.1e-267 yitY C D-arabinono-1,4-lactone oxidase
CGAIOGLK_00251 1.7e-88 norB G Major Facilitator Superfamily
CGAIOGLK_00252 4.3e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CGAIOGLK_00253 2e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CGAIOGLK_00254 1.6e-135 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
CGAIOGLK_00255 2.2e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
CGAIOGLK_00256 4.4e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
CGAIOGLK_00257 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
CGAIOGLK_00258 1.5e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CGAIOGLK_00259 9.5e-28 yjzC S YjzC-like protein
CGAIOGLK_00260 2.3e-16 yjzD S Protein of unknown function (DUF2929)
CGAIOGLK_00261 3.1e-141 yjaU I carboxylic ester hydrolase activity
CGAIOGLK_00262 1.8e-101 yjaV
CGAIOGLK_00263 2.5e-183 med S Transcriptional activator protein med
CGAIOGLK_00264 7.3e-26 comZ S ComZ
CGAIOGLK_00265 2.7e-22 yjzB
CGAIOGLK_00266 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CGAIOGLK_00267 9.9e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CGAIOGLK_00268 3e-150 yjaZ O Zn-dependent protease
CGAIOGLK_00269 3.9e-184 appD P Belongs to the ABC transporter superfamily
CGAIOGLK_00270 7.2e-186 appF E Belongs to the ABC transporter superfamily
CGAIOGLK_00271 2.4e-287 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
CGAIOGLK_00272 7.7e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGAIOGLK_00273 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGAIOGLK_00274 5e-147 yjbA S Belongs to the UPF0736 family
CGAIOGLK_00275 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
CGAIOGLK_00276 9.4e-308 oppA E ABC transporter substrate-binding protein
CGAIOGLK_00277 7.8e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGAIOGLK_00278 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGAIOGLK_00279 6.8e-198 oppD P Belongs to the ABC transporter superfamily
CGAIOGLK_00280 5.5e-172 oppF E Belongs to the ABC transporter superfamily
CGAIOGLK_00281 2.3e-213 yjbB EGP Major Facilitator Superfamily
CGAIOGLK_00282 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CGAIOGLK_00283 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CGAIOGLK_00284 6e-112 yjbE P Integral membrane protein TerC family
CGAIOGLK_00285 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
CGAIOGLK_00286 9.5e-222 yjbF S Competence protein
CGAIOGLK_00287 0.0 pepF E oligoendopeptidase F
CGAIOGLK_00288 1.8e-20
CGAIOGLK_00290 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
CGAIOGLK_00291 3.7e-72 yjbI S Bacterial-like globin
CGAIOGLK_00292 3.1e-85 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
CGAIOGLK_00293 2.3e-99 yjbK S protein conserved in bacteria
CGAIOGLK_00294 7.1e-62 yjbL S Belongs to the UPF0738 family
CGAIOGLK_00295 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
CGAIOGLK_00296 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CGAIOGLK_00297 1.3e-157 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CGAIOGLK_00298 5.1e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
CGAIOGLK_00299 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
CGAIOGLK_00300 9.9e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CGAIOGLK_00301 9.3e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
CGAIOGLK_00302 8.8e-217 thiO 1.4.3.19 E Glycine oxidase
CGAIOGLK_00303 6.7e-30 thiS H thiamine diphosphate biosynthetic process
CGAIOGLK_00304 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
CGAIOGLK_00305 6e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
CGAIOGLK_00306 5.8e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
CGAIOGLK_00307 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
CGAIOGLK_00308 1.4e-52 yjbX S Spore coat protein
CGAIOGLK_00309 4.4e-82 cotZ S Spore coat protein
CGAIOGLK_00310 7.6e-96 cotY S Spore coat protein Z
CGAIOGLK_00311 1.2e-67 cotX S Spore Coat Protein X and V domain
CGAIOGLK_00312 7.4e-23 cotW
CGAIOGLK_00313 7.2e-49 cotV S Spore Coat Protein X and V domain
CGAIOGLK_00314 4.3e-56 yjcA S Protein of unknown function (DUF1360)
CGAIOGLK_00317 2.9e-38 spoVIF S Stage VI sporulation protein F
CGAIOGLK_00318 0.0 yjcD 3.6.4.12 L DNA helicase
CGAIOGLK_00319 1.7e-38
CGAIOGLK_00320 3.9e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CGAIOGLK_00321 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
CGAIOGLK_00322 1.8e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
CGAIOGLK_00323 8.6e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
CGAIOGLK_00324 6.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
CGAIOGLK_00325 5.3e-98 rimJ 2.3.1.128 J Alanine acetyltransferase
CGAIOGLK_00326 1.6e-211 yjcL S Protein of unknown function (DUF819)
CGAIOGLK_00328 1.7e-48
CGAIOGLK_00329 2.9e-220 yobL S Bacterial EndoU nuclease
CGAIOGLK_00330 3.7e-21
CGAIOGLK_00334 1.2e-27 K Helix-turn-helix domain
CGAIOGLK_00336 3.5e-33
CGAIOGLK_00337 2.2e-08
CGAIOGLK_00339 1.4e-10
CGAIOGLK_00342 4.6e-190 S Putative amidase domain
CGAIOGLK_00343 4.4e-44 yjcN
CGAIOGLK_00344 1.1e-48 yqaS L DNA packaging
CGAIOGLK_00345 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
CGAIOGLK_00346 9.2e-141 IQ Enoyl-(Acyl carrier protein) reductase
CGAIOGLK_00348 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
CGAIOGLK_00349 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
CGAIOGLK_00350 8.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
CGAIOGLK_00351 2.7e-49 yjdF S Protein of unknown function (DUF2992)
CGAIOGLK_00352 1.8e-92 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
CGAIOGLK_00354 3.4e-80 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CGAIOGLK_00355 4.2e-29 S Domain of unknown function (DUF4177)
CGAIOGLK_00356 7.8e-52 yjdJ S Domain of unknown function (DUF4306)
CGAIOGLK_00357 7.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
CGAIOGLK_00359 1.1e-264 xynD 3.5.1.104 G Polysaccharide deacetylase
CGAIOGLK_00360 9.4e-83 S Protein of unknown function (DUF2690)
CGAIOGLK_00361 2.3e-20 yjfB S Putative motility protein
CGAIOGLK_00362 3.2e-164 yjfC O Predicted Zn-dependent protease (DUF2268)
CGAIOGLK_00363 1.2e-45 T PhoQ Sensor
CGAIOGLK_00364 9.9e-103 yjgB S Domain of unknown function (DUF4309)
CGAIOGLK_00365 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
CGAIOGLK_00366 4.3e-95 yjgD S Protein of unknown function (DUF1641)
CGAIOGLK_00367 8.7e-07 S Domain of unknown function (DUF4352)
CGAIOGLK_00368 4.9e-116 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
CGAIOGLK_00370 2.2e-221 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
CGAIOGLK_00371 7.2e-217 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
CGAIOGLK_00372 8.2e-30
CGAIOGLK_00373 1e-145 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
CGAIOGLK_00374 7.3e-122 ybbM S transport system, permease component
CGAIOGLK_00375 2.6e-135 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
CGAIOGLK_00376 2.3e-176 yjlA EG Putative multidrug resistance efflux transporter
CGAIOGLK_00377 2e-91 yjlB S Cupin domain
CGAIOGLK_00378 1.2e-65 yjlC S Protein of unknown function (DUF1641)
CGAIOGLK_00379 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
CGAIOGLK_00380 7.9e-279 uxaC 5.3.1.12 G glucuronate isomerase
CGAIOGLK_00381 5.1e-246 yjmB G symporter YjmB
CGAIOGLK_00382 3.5e-188 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
CGAIOGLK_00383 1.9e-189 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
CGAIOGLK_00384 2.3e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
CGAIOGLK_00385 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CGAIOGLK_00386 3.1e-226 exuT G Sugar (and other) transporter
CGAIOGLK_00387 6.8e-184 exuR K transcriptional
CGAIOGLK_00388 4.9e-284 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
CGAIOGLK_00389 5.8e-280 uxaA 4.2.1.7, 4.4.1.24 G Altronate
CGAIOGLK_00390 4.3e-130 MA20_18170 S membrane transporter protein
CGAIOGLK_00391 2.3e-78 yjoA S DinB family
CGAIOGLK_00392 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
CGAIOGLK_00393 1.9e-211 S response regulator aspartate phosphatase
CGAIOGLK_00395 6.3e-41 S YCII-related domain
CGAIOGLK_00396 8.5e-168 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
CGAIOGLK_00397 1.8e-60 yjqA S Bacterial PH domain
CGAIOGLK_00398 2.1e-111 yjqB S Pfam:DUF867
CGAIOGLK_00399 2.8e-159 ydbD P Catalase
CGAIOGLK_00400 9.6e-109 xkdA E IrrE N-terminal-like domain
CGAIOGLK_00401 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
CGAIOGLK_00403 5.9e-157 xkdB K sequence-specific DNA binding
CGAIOGLK_00404 4.1e-118 xkdC L Bacterial dnaA protein
CGAIOGLK_00407 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
CGAIOGLK_00408 1.8e-84 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
CGAIOGLK_00409 4.5e-138 xtmA L phage terminase small subunit
CGAIOGLK_00410 1.8e-253 xtmB S phage terminase, large subunit
CGAIOGLK_00411 4.6e-285 yqbA S portal protein
CGAIOGLK_00412 3.5e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
CGAIOGLK_00413 1.7e-168 xkdG S Phage capsid family
CGAIOGLK_00414 5.1e-63 yqbG S Protein of unknown function (DUF3199)
CGAIOGLK_00415 5.6e-64 yqbH S Domain of unknown function (DUF3599)
CGAIOGLK_00416 9.9e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
CGAIOGLK_00417 3.2e-77 xkdJ
CGAIOGLK_00418 9.3e-256 xkdK S Phage tail sheath C-terminal domain
CGAIOGLK_00419 6.1e-76 xkdM S Phage tail tube protein
CGAIOGLK_00420 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
CGAIOGLK_00421 0.0 xkdO L Transglycosylase SLT domain
CGAIOGLK_00422 5.4e-121 xkdP S Lysin motif
CGAIOGLK_00423 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
CGAIOGLK_00424 2.1e-39 xkdR S Protein of unknown function (DUF2577)
CGAIOGLK_00425 4.1e-69 xkdS S Protein of unknown function (DUF2634)
CGAIOGLK_00426 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
CGAIOGLK_00427 2e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
CGAIOGLK_00428 5.6e-40
CGAIOGLK_00429 2.9e-261
CGAIOGLK_00430 7e-53 xkdW S XkdW protein
CGAIOGLK_00431 1.1e-22 xkdX
CGAIOGLK_00432 9.9e-152 xepA
CGAIOGLK_00433 2.8e-39 xhlA S Haemolysin XhlA
CGAIOGLK_00434 1.3e-38 xhlB S SPP1 phage holin
CGAIOGLK_00435 3.8e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
CGAIOGLK_00437 6.7e-23 spoIISB S Stage II sporulation protein SB
CGAIOGLK_00438 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
CGAIOGLK_00439 5.8e-175 pit P phosphate transporter
CGAIOGLK_00440 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
CGAIOGLK_00441 2.6e-239 steT E amino acid
CGAIOGLK_00442 6.7e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
CGAIOGLK_00443 7.7e-11 mhqA E COG0346 Lactoylglutathione lyase and related lyases
CGAIOGLK_00444 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CGAIOGLK_00445 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
CGAIOGLK_00447 8.5e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CGAIOGLK_00448 3.7e-135 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
CGAIOGLK_00449 5.1e-153 dppA E D-aminopeptidase
CGAIOGLK_00450 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGAIOGLK_00451 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGAIOGLK_00452 2.8e-185 dppD P Belongs to the ABC transporter superfamily
CGAIOGLK_00453 0.0 dppE E ABC transporter substrate-binding protein
CGAIOGLK_00455 2.1e-174 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
CGAIOGLK_00456 3.1e-198 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
CGAIOGLK_00457 4e-167 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
CGAIOGLK_00458 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
CGAIOGLK_00459 1.5e-202 pgl 3.1.1.31 G 6-phosphogluconolactonase
CGAIOGLK_00460 1.2e-160 ykgA E Amidinotransferase
CGAIOGLK_00461 1.5e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
CGAIOGLK_00462 1e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CGAIOGLK_00463 1e-07
CGAIOGLK_00464 2.7e-129 ykjA S Protein of unknown function (DUF421)
CGAIOGLK_00465 1e-98 ykkA S Protein of unknown function (DUF664)
CGAIOGLK_00466 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CGAIOGLK_00467 3.5e-55 ykkC P Multidrug resistance protein
CGAIOGLK_00468 7e-50 ykkD P Multidrug resistance protein
CGAIOGLK_00469 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
CGAIOGLK_00470 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CGAIOGLK_00471 2.4e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CGAIOGLK_00473 1.3e-70 ohrA O Organic hydroperoxide resistance protein
CGAIOGLK_00474 5.7e-74 ohrR K COG1846 Transcriptional regulators
CGAIOGLK_00475 8.4e-72 ohrB O Organic hydroperoxide resistance protein
CGAIOGLK_00476 5.5e-83 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
CGAIOGLK_00477 6.6e-71 5.4.2.11 G Belongs to the phosphoglycerate mutase family
CGAIOGLK_00478 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CGAIOGLK_00479 5e-176 isp O Belongs to the peptidase S8 family
CGAIOGLK_00480 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CGAIOGLK_00481 2.9e-134 ykoC P Cobalt transport protein
CGAIOGLK_00482 2.6e-305 P ABC transporter, ATP-binding protein
CGAIOGLK_00483 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
CGAIOGLK_00484 5.1e-110 ykoF S YKOF-related Family
CGAIOGLK_00485 1.8e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CGAIOGLK_00486 4.9e-241 ykoH 2.7.13.3 T Histidine kinase
CGAIOGLK_00487 3.1e-111 ykoI S Peptidase propeptide and YPEB domain
CGAIOGLK_00488 1.6e-83 ykoJ S Peptidase propeptide and YPEB domain
CGAIOGLK_00491 2.2e-222 mgtE P Acts as a magnesium transporter
CGAIOGLK_00492 1.4e-53 tnrA K transcriptional
CGAIOGLK_00493 5.9e-18
CGAIOGLK_00494 6.9e-26 ykoL
CGAIOGLK_00495 1.3e-81 mhqR K transcriptional
CGAIOGLK_00496 1.2e-210 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
CGAIOGLK_00497 3.7e-99 ykoP G polysaccharide deacetylase
CGAIOGLK_00498 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
CGAIOGLK_00499 0.0 ykoS
CGAIOGLK_00500 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
CGAIOGLK_00501 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
CGAIOGLK_00502 3.6e-160 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CGAIOGLK_00503 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
CGAIOGLK_00504 3.5e-109 ykoX S membrane-associated protein
CGAIOGLK_00505 4.6e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
CGAIOGLK_00506 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CGAIOGLK_00507 4.5e-115 rsgI S Anti-sigma factor N-terminus
CGAIOGLK_00508 1.9e-26 sspD S small acid-soluble spore protein
CGAIOGLK_00509 1.5e-124 ykrK S Domain of unknown function (DUF1836)
CGAIOGLK_00510 1.3e-154 htpX O Belongs to the peptidase M48B family
CGAIOGLK_00511 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
CGAIOGLK_00512 1.2e-10 ydfR S Protein of unknown function (DUF421)
CGAIOGLK_00513 4.1e-18 ykzE
CGAIOGLK_00514 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
CGAIOGLK_00515 0.0 kinE 2.7.13.3 T Histidine kinase
CGAIOGLK_00516 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CGAIOGLK_00518 8.2e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CGAIOGLK_00519 7e-228 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CGAIOGLK_00520 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
CGAIOGLK_00521 9.8e-230 mtnE 2.6.1.83 E Aminotransferase
CGAIOGLK_00522 1.3e-229 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
CGAIOGLK_00523 8.3e-136 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
CGAIOGLK_00524 4.7e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
CGAIOGLK_00525 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CGAIOGLK_00526 2.2e-51 XK27_09985 S Protein of unknown function (DUF1232)
CGAIOGLK_00527 7.5e-10 S Spo0E like sporulation regulatory protein
CGAIOGLK_00528 2.6e-63 eag
CGAIOGLK_00529 1.4e-273 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
CGAIOGLK_00530 1.3e-75 ykvE K transcriptional
CGAIOGLK_00531 2.5e-125 motB N Flagellar motor protein
CGAIOGLK_00532 1e-137 motA N flagellar motor
CGAIOGLK_00533 0.0 clpE O Belongs to the ClpA ClpB family
CGAIOGLK_00534 1.8e-179 ykvI S membrane
CGAIOGLK_00535 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CGAIOGLK_00536 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
CGAIOGLK_00537 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
CGAIOGLK_00538 2.9e-95 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CGAIOGLK_00539 3.8e-60 ykvN K HxlR-like helix-turn-helix
CGAIOGLK_00540 1.4e-133 IQ Enoyl-(Acyl carrier protein) reductase
CGAIOGLK_00541 9.2e-214 ykvP 3.5.1.28 M Glycosyl transferases group 1
CGAIOGLK_00542 6.5e-29 3.5.1.104 M LysM domain
CGAIOGLK_00543 1.5e-161 G Glycosyl hydrolases family 18
CGAIOGLK_00544 5.6e-46 ykvR S Protein of unknown function (DUF3219)
CGAIOGLK_00545 6e-25 ykvS S protein conserved in bacteria
CGAIOGLK_00546 2.8e-28
CGAIOGLK_00547 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
CGAIOGLK_00548 2.9e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CGAIOGLK_00549 9.2e-89 stoA CO thiol-disulfide
CGAIOGLK_00550 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
CGAIOGLK_00551 2.3e-09
CGAIOGLK_00552 4.8e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
CGAIOGLK_00553 6.4e-179 ykvZ 5.1.1.1 K Transcriptional regulator
CGAIOGLK_00554 7.6e-128 glcT K antiterminator
CGAIOGLK_00555 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CGAIOGLK_00556 2.1e-39 ptsH G phosphocarrier protein HPr
CGAIOGLK_00557 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CGAIOGLK_00558 7.2e-39 splA S Transcriptional regulator
CGAIOGLK_00559 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
CGAIOGLK_00560 4.3e-129 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CGAIOGLK_00561 1.6e-261 mcpC NT chemotaxis protein
CGAIOGLK_00562 5.6e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
CGAIOGLK_00563 8e-124 ykwD J protein with SCP PR1 domains
CGAIOGLK_00564 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
CGAIOGLK_00565 0.0 pilS 2.7.13.3 T Histidine kinase
CGAIOGLK_00566 6.3e-221 patA 2.6.1.1 E Aminotransferase
CGAIOGLK_00567 2.2e-15
CGAIOGLK_00568 1.6e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
CGAIOGLK_00569 1.7e-84 ykyB S YkyB-like protein
CGAIOGLK_00570 3.4e-236 ykuC EGP Major facilitator Superfamily
CGAIOGLK_00571 1.8e-87 ykuD S protein conserved in bacteria
CGAIOGLK_00572 9.4e-166 ykuE S Metallophosphoesterase
CGAIOGLK_00573 8.4e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CGAIOGLK_00574 5.2e-234 ykuI T Diguanylate phosphodiesterase
CGAIOGLK_00575 3.9e-37 ykuJ S protein conserved in bacteria
CGAIOGLK_00576 4.4e-94 ykuK S Ribonuclease H-like
CGAIOGLK_00577 3.9e-27 ykzF S Antirepressor AbbA
CGAIOGLK_00578 1.6e-76 ykuL S CBS domain
CGAIOGLK_00579 3.5e-168 ccpC K Transcriptional regulator
CGAIOGLK_00580 2.2e-84 fld C Flavodoxin domain
CGAIOGLK_00581 1.8e-175 ykuO
CGAIOGLK_00582 3.9e-78 fld C Flavodoxin
CGAIOGLK_00583 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CGAIOGLK_00584 2.4e-214 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CGAIOGLK_00585 9e-37 ykuS S Belongs to the UPF0180 family
CGAIOGLK_00586 8.8e-142 ykuT M Mechanosensitive ion channel
CGAIOGLK_00587 3.9e-101 ykuU O Alkyl hydroperoxide reductase
CGAIOGLK_00588 5.4e-80 ykuV CO thiol-disulfide
CGAIOGLK_00589 5.8e-95 rok K Repressor of ComK
CGAIOGLK_00590 4.2e-146 yknT
CGAIOGLK_00591 7.4e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
CGAIOGLK_00592 2.9e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
CGAIOGLK_00593 2.4e-245 moeA 2.10.1.1 H molybdopterin
CGAIOGLK_00594 5.5e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
CGAIOGLK_00595 7.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
CGAIOGLK_00596 4.1e-31 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CGAIOGLK_00597 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
CGAIOGLK_00598 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
CGAIOGLK_00599 2.2e-117 yknW S Yip1 domain
CGAIOGLK_00600 1.2e-157 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CGAIOGLK_00601 2.5e-124 macB V ABC transporter, ATP-binding protein
CGAIOGLK_00602 2.7e-211 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
CGAIOGLK_00603 3.1e-136 fruR K Transcriptional regulator
CGAIOGLK_00604 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
CGAIOGLK_00605 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
CGAIOGLK_00606 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
CGAIOGLK_00607 8.1e-39 ykoA
CGAIOGLK_00608 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
CGAIOGLK_00609 3.4e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CGAIOGLK_00610 5.9e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
CGAIOGLK_00611 1.1e-12 S Uncharacterized protein YkpC
CGAIOGLK_00612 2.2e-182 mreB D Rod-share determining protein MreBH
CGAIOGLK_00613 1.5e-43 abrB K of stationary sporulation gene expression
CGAIOGLK_00614 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
CGAIOGLK_00615 1.6e-162 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
CGAIOGLK_00616 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
CGAIOGLK_00617 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CGAIOGLK_00618 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CGAIOGLK_00619 8.2e-31 ykzG S Belongs to the UPF0356 family
CGAIOGLK_00620 5.5e-147 ykrA S hydrolases of the HAD superfamily
CGAIOGLK_00621 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CGAIOGLK_00623 3.9e-108 recN L Putative cell-wall binding lipoprotein
CGAIOGLK_00624 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
CGAIOGLK_00625 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CGAIOGLK_00626 4.9e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CGAIOGLK_00627 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
CGAIOGLK_00628 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
CGAIOGLK_00629 1e-276 speA 4.1.1.19 E Arginine
CGAIOGLK_00630 1e-41 yktA S Belongs to the UPF0223 family
CGAIOGLK_00631 5.1e-116 yktB S Belongs to the UPF0637 family
CGAIOGLK_00632 7.1e-26 ykzI
CGAIOGLK_00633 1.8e-150 suhB 3.1.3.25 G Inositol monophosphatase
CGAIOGLK_00634 2e-77 ykzC S Acetyltransferase (GNAT) family
CGAIOGLK_00635 1.2e-171 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CGAIOGLK_00636 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
CGAIOGLK_00637 0.0 ylaA
CGAIOGLK_00638 3e-41 ylaB
CGAIOGLK_00639 1.2e-11 sigC S Putative zinc-finger
CGAIOGLK_00640 2.6e-37 ylaE
CGAIOGLK_00641 8.2e-22 S Family of unknown function (DUF5325)
CGAIOGLK_00642 0.0 typA T GTP-binding protein TypA
CGAIOGLK_00643 4.2e-47 ylaH S YlaH-like protein
CGAIOGLK_00644 2.5e-32 ylaI S protein conserved in bacteria
CGAIOGLK_00645 1.2e-88 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CGAIOGLK_00646 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
CGAIOGLK_00647 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CGAIOGLK_00648 1e-170 glsA 3.5.1.2 E Belongs to the glutaminase family
CGAIOGLK_00649 8.7e-44 ylaN S Belongs to the UPF0358 family
CGAIOGLK_00650 5.9e-214 ftsW D Belongs to the SEDS family
CGAIOGLK_00651 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CGAIOGLK_00652 6.5e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
CGAIOGLK_00653 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
CGAIOGLK_00654 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
CGAIOGLK_00655 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CGAIOGLK_00656 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
CGAIOGLK_00657 2.3e-51 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
CGAIOGLK_00658 8.8e-167 ctaG S cytochrome c oxidase
CGAIOGLK_00659 3.5e-61 ylbA S YugN-like family
CGAIOGLK_00660 2.6e-74 ylbB T COG0517 FOG CBS domain
CGAIOGLK_00661 4.3e-200 ylbC S protein with SCP PR1 domains
CGAIOGLK_00662 4.1e-63 ylbD S Putative coat protein
CGAIOGLK_00663 6.7e-37 ylbE S YlbE-like protein
CGAIOGLK_00664 1.8e-75 ylbF S Belongs to the UPF0342 family
CGAIOGLK_00665 3.7e-38 ylbG S UPF0298 protein
CGAIOGLK_00666 1.6e-97 rsmD 2.1.1.171 L Methyltransferase
CGAIOGLK_00667 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CGAIOGLK_00668 1e-218 ylbJ S Sporulation integral membrane protein YlbJ
CGAIOGLK_00669 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
CGAIOGLK_00670 6.8e-187 ylbL T Belongs to the peptidase S16 family
CGAIOGLK_00671 3.5e-230 ylbM S Belongs to the UPF0348 family
CGAIOGLK_00673 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
CGAIOGLK_00674 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
CGAIOGLK_00675 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
CGAIOGLK_00676 1.5e-88 ylbP K n-acetyltransferase
CGAIOGLK_00677 8e-168 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CGAIOGLK_00678 1.6e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CGAIOGLK_00679 2.9e-78 mraZ K Belongs to the MraZ family
CGAIOGLK_00680 2.8e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CGAIOGLK_00681 3.7e-44 ftsL D Essential cell division protein
CGAIOGLK_00682 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
CGAIOGLK_00683 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
CGAIOGLK_00684 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CGAIOGLK_00685 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CGAIOGLK_00686 8.5e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CGAIOGLK_00687 5.7e-186 spoVE D Belongs to the SEDS family
CGAIOGLK_00688 4.3e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CGAIOGLK_00689 5.3e-167 murB 1.3.1.98 M cell wall formation
CGAIOGLK_00690 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CGAIOGLK_00691 4.1e-103 ylxW S protein conserved in bacteria
CGAIOGLK_00692 1.2e-90 ylxX S protein conserved in bacteria
CGAIOGLK_00693 6.2e-58 sbp S small basic protein
CGAIOGLK_00694 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CGAIOGLK_00695 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CGAIOGLK_00696 0.0 bpr O COG1404 Subtilisin-like serine proteases
CGAIOGLK_00697 9.8e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
CGAIOGLK_00698 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CGAIOGLK_00699 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CGAIOGLK_00700 5.9e-146 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
CGAIOGLK_00701 2.3e-253 argE 3.5.1.16 E Acetylornithine deacetylase
CGAIOGLK_00702 2.4e-37 ylmC S sporulation protein
CGAIOGLK_00703 5.9e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
CGAIOGLK_00704 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CGAIOGLK_00705 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CGAIOGLK_00706 1.3e-39 yggT S membrane
CGAIOGLK_00707 4.1e-136 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
CGAIOGLK_00708 2.6e-67 divIVA D Cell division initiation protein
CGAIOGLK_00709 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CGAIOGLK_00710 8.5e-63 dksA T COG1734 DnaK suppressor protein
CGAIOGLK_00711 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CGAIOGLK_00712 5.5e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CGAIOGLK_00713 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CGAIOGLK_00714 9.9e-231 pyrP F Xanthine uracil
CGAIOGLK_00715 1.5e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
CGAIOGLK_00716 3.5e-249 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CGAIOGLK_00717 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
CGAIOGLK_00718 0.0 carB 6.3.5.5 F Belongs to the CarB family
CGAIOGLK_00719 1.4e-144 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
CGAIOGLK_00720 1.4e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CGAIOGLK_00721 3e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CGAIOGLK_00722 1e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CGAIOGLK_00724 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
CGAIOGLK_00725 3.2e-179 cysP P phosphate transporter
CGAIOGLK_00726 5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
CGAIOGLK_00727 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
CGAIOGLK_00728 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
CGAIOGLK_00729 9.2e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
CGAIOGLK_00730 8.2e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
CGAIOGLK_00731 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
CGAIOGLK_00732 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
CGAIOGLK_00733 9e-156 yloC S stress-induced protein
CGAIOGLK_00734 1.5e-40 ylzA S Belongs to the UPF0296 family
CGAIOGLK_00735 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
CGAIOGLK_00736 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CGAIOGLK_00737 8.2e-224 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CGAIOGLK_00738 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CGAIOGLK_00739 1.3e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CGAIOGLK_00740 3.8e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CGAIOGLK_00741 8.4e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CGAIOGLK_00742 1.4e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CGAIOGLK_00743 1.6e-140 stp 3.1.3.16 T phosphatase
CGAIOGLK_00744 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
CGAIOGLK_00745 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CGAIOGLK_00746 3.6e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
CGAIOGLK_00747 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
CGAIOGLK_00748 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
CGAIOGLK_00749 5.5e-59 asp S protein conserved in bacteria
CGAIOGLK_00750 5.6e-300 yloV S kinase related to dihydroxyacetone kinase
CGAIOGLK_00751 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
CGAIOGLK_00752 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
CGAIOGLK_00753 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CGAIOGLK_00754 1.1e-77 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
CGAIOGLK_00755 1.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CGAIOGLK_00756 7.7e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
CGAIOGLK_00757 6.1e-129 IQ reductase
CGAIOGLK_00758 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CGAIOGLK_00759 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CGAIOGLK_00760 0.0 smc D Required for chromosome condensation and partitioning
CGAIOGLK_00761 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CGAIOGLK_00762 2.9e-87
CGAIOGLK_00763 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CGAIOGLK_00764 1e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CGAIOGLK_00765 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
CGAIOGLK_00766 4.5e-36 ylqC S Belongs to the UPF0109 family
CGAIOGLK_00767 2e-59 ylqD S YlqD protein
CGAIOGLK_00768 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CGAIOGLK_00769 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
CGAIOGLK_00770 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CGAIOGLK_00771 7.9e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CGAIOGLK_00772 2e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CGAIOGLK_00773 8.5e-291 ylqG
CGAIOGLK_00774 8.7e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
CGAIOGLK_00775 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
CGAIOGLK_00776 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CGAIOGLK_00777 5e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
CGAIOGLK_00778 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CGAIOGLK_00779 4.8e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CGAIOGLK_00780 2.5e-169 xerC L tyrosine recombinase XerC
CGAIOGLK_00781 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CGAIOGLK_00782 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CGAIOGLK_00783 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CGAIOGLK_00784 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
CGAIOGLK_00785 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
CGAIOGLK_00786 1.9e-31 fliE N Flagellar hook-basal body
CGAIOGLK_00787 2.6e-254 fliF N The M ring may be actively involved in energy transduction
CGAIOGLK_00788 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
CGAIOGLK_00789 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
CGAIOGLK_00790 7.2e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
CGAIOGLK_00791 3.2e-69 fliJ N Flagellar biosynthesis chaperone
CGAIOGLK_00792 1.3e-36 ylxF S MgtE intracellular N domain
CGAIOGLK_00793 2.5e-219 fliK N Flagellar hook-length control protein
CGAIOGLK_00794 2.3e-72 flgD N Flagellar basal body rod modification protein
CGAIOGLK_00795 8.2e-140 flgG N Flagellar basal body rod
CGAIOGLK_00796 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
CGAIOGLK_00797 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
CGAIOGLK_00798 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CGAIOGLK_00799 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
CGAIOGLK_00800 2.7e-96 fliZ N Flagellar biosynthesis protein, FliO
CGAIOGLK_00801 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
CGAIOGLK_00802 2.2e-36 fliQ N Role in flagellar biosynthesis
CGAIOGLK_00803 3.6e-132 fliR N Flagellar biosynthetic protein FliR
CGAIOGLK_00804 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CGAIOGLK_00805 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CGAIOGLK_00806 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
CGAIOGLK_00807 2.2e-157 flhG D Belongs to the ParA family
CGAIOGLK_00808 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
CGAIOGLK_00809 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
CGAIOGLK_00810 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
CGAIOGLK_00811 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
CGAIOGLK_00812 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
CGAIOGLK_00813 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CGAIOGLK_00814 5.3e-76 ylxL
CGAIOGLK_00815 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
CGAIOGLK_00816 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CGAIOGLK_00817 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
CGAIOGLK_00818 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CGAIOGLK_00819 2.4e-144 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CGAIOGLK_00820 2.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
CGAIOGLK_00821 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
CGAIOGLK_00822 7.7e-233 rasP M zinc metalloprotease
CGAIOGLK_00823 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CGAIOGLK_00824 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CGAIOGLK_00825 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
CGAIOGLK_00826 1.1e-203 nusA K Participates in both transcription termination and antitermination
CGAIOGLK_00827 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
CGAIOGLK_00828 3.1e-47 ylxQ J ribosomal protein
CGAIOGLK_00829 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CGAIOGLK_00830 3e-44 ylxP S protein conserved in bacteria
CGAIOGLK_00831 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CGAIOGLK_00832 5.6e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CGAIOGLK_00833 3e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
CGAIOGLK_00834 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CGAIOGLK_00835 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
CGAIOGLK_00836 1.6e-182 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
CGAIOGLK_00837 4.4e-233 pepR S Belongs to the peptidase M16 family
CGAIOGLK_00838 2.6e-42 ymxH S YlmC YmxH family
CGAIOGLK_00839 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
CGAIOGLK_00840 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
CGAIOGLK_00841 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CGAIOGLK_00842 5.9e-222 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
CGAIOGLK_00843 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CGAIOGLK_00844 7.3e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CGAIOGLK_00845 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
CGAIOGLK_00846 4.4e-32 S YlzJ-like protein
CGAIOGLK_00847 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
CGAIOGLK_00848 1.4e-133 ymfC K Transcriptional regulator
CGAIOGLK_00849 3.8e-205 ymfD EGP Major facilitator Superfamily
CGAIOGLK_00850 7e-234 ymfF S Peptidase M16
CGAIOGLK_00851 4.1e-242 ymfH S zinc protease
CGAIOGLK_00852 7.8e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
CGAIOGLK_00853 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
CGAIOGLK_00854 2.7e-143 ymfK S Protein of unknown function (DUF3388)
CGAIOGLK_00855 1.9e-124 ymfM S protein conserved in bacteria
CGAIOGLK_00856 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CGAIOGLK_00857 1.3e-235 cinA 3.5.1.42 S Belongs to the CinA family
CGAIOGLK_00858 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CGAIOGLK_00859 1.3e-213 pbpX V Beta-lactamase
CGAIOGLK_00860 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
CGAIOGLK_00861 1.9e-152 ymdB S protein conserved in bacteria
CGAIOGLK_00862 1.2e-36 spoVS S Stage V sporulation protein S
CGAIOGLK_00863 7.3e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
CGAIOGLK_00864 2.5e-217 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
CGAIOGLK_00865 6.5e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CGAIOGLK_00866 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
CGAIOGLK_00867 2.2e-88 cotE S Spore coat protein
CGAIOGLK_00868 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CGAIOGLK_00869 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CGAIOGLK_00870 4.1e-67 S Regulatory protein YrvL
CGAIOGLK_00872 2.3e-96 ymcC S Membrane
CGAIOGLK_00873 2.9e-108 pksA K Transcriptional regulator
CGAIOGLK_00874 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
CGAIOGLK_00876 2.2e-162 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
CGAIOGLK_00878 6e-185 pksD Q Acyl transferase domain
CGAIOGLK_00879 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
CGAIOGLK_00880 1.4e-37 acpK IQ Phosphopantetheine attachment site
CGAIOGLK_00881 1.3e-237 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CGAIOGLK_00882 3.9e-245 pksG 2.3.3.10 I synthase
CGAIOGLK_00883 7.7e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
CGAIOGLK_00884 5.7e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
CGAIOGLK_00885 0.0 rhiB IQ polyketide synthase
CGAIOGLK_00886 0.0 pfaA Q Polyketide synthase of type I
CGAIOGLK_00887 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
CGAIOGLK_00888 0.0 dhbF IQ polyketide synthase
CGAIOGLK_00889 0.0 pks13 HQ Beta-ketoacyl synthase
CGAIOGLK_00890 7.4e-233 cypA C Cytochrome P450
CGAIOGLK_00891 1.2e-61 ymzB
CGAIOGLK_00892 6.6e-164 ymaE S Metallo-beta-lactamase superfamily
CGAIOGLK_00893 1.5e-250 aprX O Belongs to the peptidase S8 family
CGAIOGLK_00894 1.9e-07 K Transcriptional regulator
CGAIOGLK_00895 2.1e-126 ymaC S Replication protein
CGAIOGLK_00896 7.7e-79 ymaD O redox protein, regulator of disulfide bond formation
CGAIOGLK_00897 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
CGAIOGLK_00898 4.9e-51 ebrA P Small Multidrug Resistance protein
CGAIOGLK_00900 2.1e-46 ymaF S YmaF family
CGAIOGLK_00901 4.6e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CGAIOGLK_00902 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
CGAIOGLK_00903 3.1e-22
CGAIOGLK_00904 4.5e-22 ymzA
CGAIOGLK_00905 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
CGAIOGLK_00906 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CGAIOGLK_00907 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CGAIOGLK_00908 2e-109 ymaB
CGAIOGLK_00909 1.2e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
CGAIOGLK_00910 6.6e-176 spoVK O stage V sporulation protein K
CGAIOGLK_00911 1e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CGAIOGLK_00912 7.4e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
CGAIOGLK_00913 3.3e-68 glnR K transcriptional
CGAIOGLK_00914 3.5e-260 glnA 6.3.1.2 E glutamine synthetase
CGAIOGLK_00915 2.2e-10
CGAIOGLK_00916 2.3e-31
CGAIOGLK_00917 1.2e-69 Q Collagen triple helix repeat (20 copies)
CGAIOGLK_00918 6.3e-93 M Glycosyltransferase like family
CGAIOGLK_00919 1.3e-120 H Methionine biosynthesis protein MetW
CGAIOGLK_00920 3e-196 M COG0463 Glycosyltransferases involved in cell wall biogenesis
CGAIOGLK_00921 1.3e-217 sumf2 2.1.1.295 GT2,GT4 H N-terminal domain of galactosyltransferase
CGAIOGLK_00923 8.1e-99 ynaD J Acetyltransferase (GNAT) domain
CGAIOGLK_00925 6.8e-74 S CAAX protease self-immunity
CGAIOGLK_00927 3e-81 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
CGAIOGLK_00928 1.1e-253 xynT G MFS/sugar transport protein
CGAIOGLK_00929 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
CGAIOGLK_00930 3.3e-214 xylR GK ROK family
CGAIOGLK_00931 2.9e-262 xylA 5.3.1.5 G Belongs to the xylose isomerase family
CGAIOGLK_00932 8.1e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
CGAIOGLK_00933 3.7e-111 yokF 3.1.31.1 L RNA catabolic process
CGAIOGLK_00934 1.8e-254 iolT EGP Major facilitator Superfamily
CGAIOGLK_00935 1e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CGAIOGLK_00936 2e-82 yncE S Protein of unknown function (DUF2691)
CGAIOGLK_00937 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
CGAIOGLK_00940 6.6e-164 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CGAIOGLK_00941 5.4e-32
CGAIOGLK_00943 2.5e-127 S Domain of unknown function, YrpD
CGAIOGLK_00946 3.9e-24 tatA U protein secretion
CGAIOGLK_00947 1.8e-71
CGAIOGLK_00948 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
CGAIOGLK_00951 8.2e-277 gerAA EG Spore germination protein
CGAIOGLK_00952 1.2e-194 gerAB U Spore germination
CGAIOGLK_00953 3.6e-219 gerLC S Spore germination protein
CGAIOGLK_00954 1.1e-152 yndG S DoxX-like family
CGAIOGLK_00955 1.4e-306 yndJ S YndJ-like protein
CGAIOGLK_00957 4.2e-133 yndL S Replication protein
CGAIOGLK_00958 6.4e-73 yndM S Protein of unknown function (DUF2512)
CGAIOGLK_00959 4.9e-78 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
CGAIOGLK_00960 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CGAIOGLK_00961 9.9e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
CGAIOGLK_00962 2.3e-111 yneB L resolvase
CGAIOGLK_00963 1.3e-32 ynzC S UPF0291 protein
CGAIOGLK_00964 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CGAIOGLK_00965 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
CGAIOGLK_00966 1.8e-28 yneF S UPF0154 protein
CGAIOGLK_00967 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
CGAIOGLK_00968 1.2e-126 ccdA O cytochrome c biogenesis protein
CGAIOGLK_00969 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
CGAIOGLK_00970 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
CGAIOGLK_00971 4.2e-74 yneK S Protein of unknown function (DUF2621)
CGAIOGLK_00972 5.9e-64 hspX O Spore coat protein
CGAIOGLK_00973 3.9e-19 sspP S Belongs to the SspP family
CGAIOGLK_00974 2.2e-14 sspO S Belongs to the SspO family
CGAIOGLK_00975 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CGAIOGLK_00976 2.7e-91 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CGAIOGLK_00978 3.1e-08 sspN S Small acid-soluble spore protein N family
CGAIOGLK_00979 3.9e-35 tlp S Belongs to the Tlp family
CGAIOGLK_00980 1.2e-73 yneP S Thioesterase-like superfamily
CGAIOGLK_00981 2.2e-53 yneQ
CGAIOGLK_00982 4.1e-49 yneR S Belongs to the HesB IscA family
CGAIOGLK_00983 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CGAIOGLK_00984 1.1e-68 yccU S CoA-binding protein
CGAIOGLK_00985 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CGAIOGLK_00986 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CGAIOGLK_00987 2.3e-12
CGAIOGLK_00988 3e-57 ynfC
CGAIOGLK_00989 5.3e-251 agcS E Sodium alanine symporter
CGAIOGLK_00990 2.6e-296 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
CGAIOGLK_00992 1.8e-250 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
CGAIOGLK_00993 4.6e-296 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
CGAIOGLK_00994 1.6e-79 yngA S membrane
CGAIOGLK_00995 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
CGAIOGLK_00996 5.5e-104 yngC S membrane-associated protein
CGAIOGLK_00997 1.2e-232 nrnB S phosphohydrolase (DHH superfamily)
CGAIOGLK_00998 5.9e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
CGAIOGLK_00999 8.3e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
CGAIOGLK_01000 8e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
CGAIOGLK_01001 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
CGAIOGLK_01002 1.7e-246 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
CGAIOGLK_01003 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
CGAIOGLK_01004 9.8e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
CGAIOGLK_01005 1.8e-31 S Family of unknown function (DUF5367)
CGAIOGLK_01007 7e-305 yngK T Glycosyl hydrolase-like 10
CGAIOGLK_01008 1.1e-63 yngL S Protein of unknown function (DUF1360)
CGAIOGLK_01009 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
CGAIOGLK_01010 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CGAIOGLK_01015 2e-08
CGAIOGLK_01022 1.3e-09
CGAIOGLK_01023 7.8e-08
CGAIOGLK_01032 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CGAIOGLK_01033 2.6e-195 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CGAIOGLK_01034 8.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
CGAIOGLK_01035 6.9e-286 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
CGAIOGLK_01036 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
CGAIOGLK_01037 2.9e-76 tspO T membrane
CGAIOGLK_01038 6.7e-206 cotI S Spore coat protein
CGAIOGLK_01039 1.8e-217 cotSA M Glycosyl transferases group 1
CGAIOGLK_01040 6.7e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
CGAIOGLK_01042 3.7e-232 ytcC M Glycosyltransferase Family 4
CGAIOGLK_01043 9.7e-180 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
CGAIOGLK_01044 2.2e-243 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CGAIOGLK_01045 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
CGAIOGLK_01046 9.7e-132 dksA T COG1734 DnaK suppressor protein
CGAIOGLK_01047 1.9e-272 menF 5.4.4.2 HQ Isochorismate synthase
CGAIOGLK_01048 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CGAIOGLK_01049 1.6e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
CGAIOGLK_01050 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CGAIOGLK_01051 1.7e-276 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
CGAIOGLK_01052 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
CGAIOGLK_01053 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
CGAIOGLK_01054 4.5e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
CGAIOGLK_01055 3.9e-232 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
CGAIOGLK_01056 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
CGAIOGLK_01057 1.1e-24 S Domain of Unknown Function (DUF1540)
CGAIOGLK_01058 4.9e-188 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
CGAIOGLK_01059 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
CGAIOGLK_01060 3.6e-41 rpmE2 J Ribosomal protein L31
CGAIOGLK_01061 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
CGAIOGLK_01062 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CGAIOGLK_01063 1.1e-72 ytkA S YtkA-like
CGAIOGLK_01065 2.1e-76 dps P Belongs to the Dps family
CGAIOGLK_01066 6e-62 ytkC S Bacteriophage holin family
CGAIOGLK_01067 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
CGAIOGLK_01068 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
CGAIOGLK_01069 1.4e-144 ytlC P ABC transporter
CGAIOGLK_01070 8e-188 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
CGAIOGLK_01071 1.6e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
CGAIOGLK_01072 1.2e-38 ytmB S Protein of unknown function (DUF2584)
CGAIOGLK_01073 8.8e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CGAIOGLK_01074 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CGAIOGLK_01075 0.0 asnB 6.3.5.4 E Asparagine synthase
CGAIOGLK_01076 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
CGAIOGLK_01077 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CGAIOGLK_01078 4.7e-148 ytpA 3.1.1.5 I Alpha beta hydrolase
CGAIOGLK_01079 3.7e-215 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
CGAIOGLK_01080 2.8e-105 ytqB J Putative rRNA methylase
CGAIOGLK_01081 2e-188 yhcC S Fe-S oxidoreductase
CGAIOGLK_01082 6.7e-41 ytzC S Protein of unknown function (DUF2524)
CGAIOGLK_01084 5.1e-66 ytrA K GntR family transcriptional regulator
CGAIOGLK_01085 1.1e-161 ytrB P abc transporter atp-binding protein
CGAIOGLK_01086 6.1e-169 P ABC-2 family transporter protein
CGAIOGLK_01087 3.4e-148
CGAIOGLK_01088 3.1e-127 ytrE V ABC transporter, ATP-binding protein
CGAIOGLK_01089 1.6e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
CGAIOGLK_01090 1.1e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CGAIOGLK_01091 2.8e-185 T PhoQ Sensor
CGAIOGLK_01092 1.1e-138 bceA V ABC transporter, ATP-binding protein
CGAIOGLK_01093 0.0 bceB V ABC transporter (permease)
CGAIOGLK_01094 2.5e-42 yttA 2.7.13.3 S Pfam Transposase IS66
CGAIOGLK_01095 6e-211 yttB EGP Major facilitator Superfamily
CGAIOGLK_01096 3.9e-142 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
CGAIOGLK_01097 7.7e-55 ytvB S Protein of unknown function (DUF4257)
CGAIOGLK_01098 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
CGAIOGLK_01099 2.1e-51 ytwF P Sulfurtransferase
CGAIOGLK_01100 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
CGAIOGLK_01101 5.4e-142 amyC P ABC transporter (permease)
CGAIOGLK_01102 1.4e-167 amyD P ABC transporter
CGAIOGLK_01103 5.7e-244 msmE G Bacterial extracellular solute-binding protein
CGAIOGLK_01104 1.5e-189 msmR K Transcriptional regulator
CGAIOGLK_01105 2.7e-171 ytaP S Acetyl xylan esterase (AXE1)
CGAIOGLK_01106 3.1e-141 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
CGAIOGLK_01107 1.9e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
CGAIOGLK_01108 3e-215 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
CGAIOGLK_01109 7.2e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CGAIOGLK_01110 5.4e-189 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CGAIOGLK_01111 2.6e-222 bioI 1.14.14.46 C Cytochrome P450
CGAIOGLK_01112 2.8e-137 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
CGAIOGLK_01113 5.8e-144 ytcP G COG0395 ABC-type sugar transport system, permease component
CGAIOGLK_01114 6.2e-290 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
CGAIOGLK_01115 0.0 ytdP K Transcriptional regulator
CGAIOGLK_01116 5.8e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
CGAIOGLK_01117 2.3e-217 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
CGAIOGLK_01118 3.3e-71 yteS G transport
CGAIOGLK_01119 3e-256 yteT S Oxidoreductase family, C-terminal alpha/beta domain
CGAIOGLK_01120 1.3e-114 yteU S Integral membrane protein
CGAIOGLK_01121 3.1e-26 yteV S Sporulation protein Cse60
CGAIOGLK_01122 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
CGAIOGLK_01123 8.2e-232 ytfP S HI0933-like protein
CGAIOGLK_01124 2.5e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CGAIOGLK_01125 1.8e-130 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CGAIOGLK_01126 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
CGAIOGLK_01127 4.8e-131 ythP V ABC transporter
CGAIOGLK_01128 2.3e-199 ythQ U Bacterial ABC transporter protein EcsB
CGAIOGLK_01129 7.2e-226 pbuO S permease
CGAIOGLK_01130 1.9e-269 pepV 3.5.1.18 E Dipeptidase
CGAIOGLK_01131 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CGAIOGLK_01132 1.2e-100 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CGAIOGLK_01133 8.5e-165 ytlQ
CGAIOGLK_01134 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
CGAIOGLK_01135 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
CGAIOGLK_01136 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
CGAIOGLK_01137 2e-45 ytzH S YtzH-like protein
CGAIOGLK_01138 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CGAIOGLK_01139 9.3e-150 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
CGAIOGLK_01140 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
CGAIOGLK_01141 1.1e-50 ytzB S small secreted protein
CGAIOGLK_01142 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
CGAIOGLK_01143 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
CGAIOGLK_01144 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
CGAIOGLK_01145 9.8e-149 ytpQ S Belongs to the UPF0354 family
CGAIOGLK_01146 2.2e-108 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CGAIOGLK_01147 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
CGAIOGLK_01148 2.1e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
CGAIOGLK_01149 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CGAIOGLK_01150 6.6e-17 ytxH S COG4980 Gas vesicle protein
CGAIOGLK_01151 3.1e-53 ytxJ O Protein of unknown function (DUF2847)
CGAIOGLK_01152 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
CGAIOGLK_01153 1.7e-182 ccpA K catabolite control protein A
CGAIOGLK_01154 2.1e-146 motA N flagellar motor
CGAIOGLK_01155 1.4e-125 motS N Flagellar motor protein
CGAIOGLK_01156 5.4e-225 acuC BQ histone deacetylase
CGAIOGLK_01157 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
CGAIOGLK_01158 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
CGAIOGLK_01159 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
CGAIOGLK_01160 5.2e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CGAIOGLK_01162 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CGAIOGLK_01163 3.4e-308 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
CGAIOGLK_01164 5.9e-88 ytsP 1.8.4.14 T GAF domain-containing protein
CGAIOGLK_01165 1e-108 yttP K Transcriptional regulator
CGAIOGLK_01166 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
CGAIOGLK_01167 1.6e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CGAIOGLK_01168 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
CGAIOGLK_01169 1e-207 iscS2 2.8.1.7 E Cysteine desulfurase
CGAIOGLK_01170 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CGAIOGLK_01171 2e-29 sspB S spore protein
CGAIOGLK_01172 5e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
CGAIOGLK_01173 0.0 ytcJ S amidohydrolase
CGAIOGLK_01174 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CGAIOGLK_01175 1.9e-178 sppA OU signal peptide peptidase SppA
CGAIOGLK_01176 8.5e-87 yteJ S RDD family
CGAIOGLK_01177 5.2e-114 ytfI S Protein of unknown function (DUF2953)
CGAIOGLK_01178 8.7e-70 ytfJ S Sporulation protein YtfJ
CGAIOGLK_01179 7.1e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CGAIOGLK_01180 7e-165 ytxK 2.1.1.72 L DNA methylase
CGAIOGLK_01181 1.4e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CGAIOGLK_01182 1e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
CGAIOGLK_01183 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
CGAIOGLK_01184 2e-266 argH 4.3.2.1 E argininosuccinate lyase
CGAIOGLK_01186 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CGAIOGLK_01187 1.7e-130 ytkL S Belongs to the UPF0173 family
CGAIOGLK_01188 5.5e-172 ytlI K LysR substrate binding domain
CGAIOGLK_01189 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
CGAIOGLK_01190 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
CGAIOGLK_01191 3.7e-148 tcyK M Bacterial periplasmic substrate-binding proteins
CGAIOGLK_01192 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
CGAIOGLK_01193 1.9e-119 tcyM U Binding-protein-dependent transport system inner membrane component
CGAIOGLK_01194 3.9e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
CGAIOGLK_01195 4.9e-182 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGAIOGLK_01196 2.1e-45 ytnI O COG0695 Glutaredoxin and related proteins
CGAIOGLK_01197 4.9e-254 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGAIOGLK_01198 2.6e-126 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
CGAIOGLK_01199 9e-234 ytnL 3.5.1.47 E hydrolase activity
CGAIOGLK_01200 3.4e-158 ytnM S membrane transporter protein
CGAIOGLK_01201 8e-241 ytoI K transcriptional regulator containing CBS domains
CGAIOGLK_01202 3.1e-47 ytpI S YtpI-like protein
CGAIOGLK_01203 5.1e-181 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
CGAIOGLK_01204 9.2e-29
CGAIOGLK_01205 8.2e-69 ytrI
CGAIOGLK_01206 3.2e-56 ytrH S Sporulation protein YtrH
CGAIOGLK_01207 0.0 dnaE 2.7.7.7 L DNA polymerase
CGAIOGLK_01208 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
CGAIOGLK_01209 2.4e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CGAIOGLK_01210 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
CGAIOGLK_01211 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
CGAIOGLK_01212 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
CGAIOGLK_01213 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
CGAIOGLK_01214 2.6e-192 ytvI S sporulation integral membrane protein YtvI
CGAIOGLK_01215 2.3e-70 yeaL S membrane
CGAIOGLK_01216 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
CGAIOGLK_01217 4.1e-242 icd 1.1.1.42 C isocitrate
CGAIOGLK_01218 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
CGAIOGLK_01219 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CGAIOGLK_01220 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
CGAIOGLK_01221 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CGAIOGLK_01222 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CGAIOGLK_01223 3.3e-107 ytaF P Probably functions as a manganese efflux pump
CGAIOGLK_01224 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CGAIOGLK_01225 8.9e-161 ytbE S reductase
CGAIOGLK_01226 7.3e-201 ytbD EGP Major facilitator Superfamily
CGAIOGLK_01227 9.9e-67 ytcD K Transcriptional regulator
CGAIOGLK_01228 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CGAIOGLK_01229 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CGAIOGLK_01230 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CGAIOGLK_01231 4.2e-264 dnaB L Membrane attachment protein
CGAIOGLK_01232 3e-173 dnaI L Primosomal protein DnaI
CGAIOGLK_01233 9.3e-110 ytxB S SNARE associated Golgi protein
CGAIOGLK_01234 1.4e-158 ytxC S YtxC-like family
CGAIOGLK_01236 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CGAIOGLK_01237 2.8e-148 ysaA S HAD-hyrolase-like
CGAIOGLK_01238 0.0 lytS 2.7.13.3 T Histidine kinase
CGAIOGLK_01239 3.1e-130 lytT T COG3279 Response regulator of the LytR AlgR family
CGAIOGLK_01240 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
CGAIOGLK_01241 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
CGAIOGLK_01243 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CGAIOGLK_01244 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
CGAIOGLK_01245 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CGAIOGLK_01246 7.5e-45 ysdA S Membrane
CGAIOGLK_01247 9.2e-68 ysdB S Sigma-w pathway protein YsdB
CGAIOGLK_01248 6.4e-204 ysdC G COG1363 Cellulase M and related proteins
CGAIOGLK_01249 3.1e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
CGAIOGLK_01250 4.6e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
CGAIOGLK_01251 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
CGAIOGLK_01252 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
CGAIOGLK_01253 3.5e-146 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
CGAIOGLK_01254 2.2e-221 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
CGAIOGLK_01255 1.3e-251 araN G carbohydrate transport
CGAIOGLK_01256 1.4e-167 araP G carbohydrate transport
CGAIOGLK_01257 9.9e-144 araQ G transport system permease
CGAIOGLK_01258 8.7e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
CGAIOGLK_01259 0.0 cstA T Carbon starvation protein
CGAIOGLK_01261 2.8e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
CGAIOGLK_01262 2.3e-256 glcF C Glycolate oxidase
CGAIOGLK_01263 1.4e-262 glcD 1.1.3.15 C Glycolate oxidase subunit
CGAIOGLK_01264 2.5e-203 ysfB KT regulator
CGAIOGLK_01265 2.6e-32 sspI S Belongs to the SspI family
CGAIOGLK_01266 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CGAIOGLK_01267 8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CGAIOGLK_01268 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CGAIOGLK_01269 9e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CGAIOGLK_01270 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CGAIOGLK_01271 1.3e-85 cvpA S membrane protein, required for colicin V production
CGAIOGLK_01272 0.0 polX L COG1796 DNA polymerase IV (family X)
CGAIOGLK_01273 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CGAIOGLK_01274 7.3e-68 yshE S membrane
CGAIOGLK_01275 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
CGAIOGLK_01276 2.7e-100 fadR K Transcriptional regulator
CGAIOGLK_01277 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
CGAIOGLK_01278 1.2e-135 etfB C Electron transfer flavoprotein
CGAIOGLK_01279 1.2e-177 etfA C Electron transfer flavoprotein
CGAIOGLK_01281 7.5e-304 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
CGAIOGLK_01282 2e-52 trxA O Belongs to the thioredoxin family
CGAIOGLK_01283 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CGAIOGLK_01284 6.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
CGAIOGLK_01285 3.5e-79 yslB S Protein of unknown function (DUF2507)
CGAIOGLK_01286 2.4e-107 sdhC C succinate dehydrogenase
CGAIOGLK_01287 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
CGAIOGLK_01288 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
CGAIOGLK_01289 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
CGAIOGLK_01290 3.3e-30 gerE K Transcriptional regulator
CGAIOGLK_01291 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
CGAIOGLK_01292 7.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
CGAIOGLK_01293 2.9e-196 gerM S COG5401 Spore germination protein
CGAIOGLK_01294 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CGAIOGLK_01295 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CGAIOGLK_01296 3.5e-91 ysnB S Phosphoesterase
CGAIOGLK_01298 1.1e-131 ysnF S protein conserved in bacteria
CGAIOGLK_01299 6e-79 ysnE K acetyltransferase
CGAIOGLK_01301 0.0 ilvB 2.2.1.6 E Acetolactate synthase
CGAIOGLK_01302 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
CGAIOGLK_01303 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CGAIOGLK_01304 4.2e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CGAIOGLK_01305 1.7e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
CGAIOGLK_01306 1.4e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CGAIOGLK_01307 5.3e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CGAIOGLK_01308 8.6e-187 ysoA H Tetratricopeptide repeat
CGAIOGLK_01309 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CGAIOGLK_01310 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CGAIOGLK_01311 3.4e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
CGAIOGLK_01312 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CGAIOGLK_01313 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
CGAIOGLK_01314 7e-89 ysxD
CGAIOGLK_01315 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CGAIOGLK_01316 3.6e-146 hemX O cytochrome C
CGAIOGLK_01317 1.1e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
CGAIOGLK_01318 2.4e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
CGAIOGLK_01319 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
CGAIOGLK_01320 2.8e-246 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
CGAIOGLK_01321 6.4e-198 spoVID M stage VI sporulation protein D
CGAIOGLK_01322 7.8e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CGAIOGLK_01323 1.6e-25
CGAIOGLK_01324 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CGAIOGLK_01325 9.6e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
CGAIOGLK_01326 3.3e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
CGAIOGLK_01327 7.1e-165 spoIIB S Sporulation related domain
CGAIOGLK_01328 2.8e-102 maf D septum formation protein Maf
CGAIOGLK_01329 1.3e-125 radC E Belongs to the UPF0758 family
CGAIOGLK_01330 1.8e-184 mreB D Rod shape-determining protein MreB
CGAIOGLK_01331 2.8e-157 mreC M Involved in formation and maintenance of cell shape
CGAIOGLK_01332 1.4e-84 mreD M shape-determining protein
CGAIOGLK_01333 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
CGAIOGLK_01334 4.7e-143 minD D Belongs to the ParA family
CGAIOGLK_01335 4.2e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
CGAIOGLK_01336 1.7e-159 spoIVFB S Stage IV sporulation protein
CGAIOGLK_01337 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
CGAIOGLK_01338 4.1e-56 ysxB J ribosomal protein
CGAIOGLK_01339 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
CGAIOGLK_01340 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
CGAIOGLK_01341 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CGAIOGLK_01342 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
CGAIOGLK_01343 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
CGAIOGLK_01344 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
CGAIOGLK_01345 7.3e-217 nifS 2.8.1.7 E Cysteine desulfurase
CGAIOGLK_01346 9.8e-302 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
CGAIOGLK_01347 4.7e-157 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
CGAIOGLK_01348 1.4e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CGAIOGLK_01349 1.8e-156 safA M spore coat assembly protein SafA
CGAIOGLK_01350 2.2e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CGAIOGLK_01351 5.5e-127 yebC K transcriptional regulatory protein
CGAIOGLK_01352 3.4e-261 alsT E Sodium alanine symporter
CGAIOGLK_01353 8.1e-52 S Family of unknown function (DUF5412)
CGAIOGLK_01355 6.5e-119 yrzF T serine threonine protein kinase
CGAIOGLK_01356 2.8e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
CGAIOGLK_01357 2e-252 csbX EGP Major facilitator Superfamily
CGAIOGLK_01358 4.8e-93 bofC S BofC C-terminal domain
CGAIOGLK_01359 7.7e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CGAIOGLK_01360 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CGAIOGLK_01361 4.5e-18 yrzS S Protein of unknown function (DUF2905)
CGAIOGLK_01362 7.5e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CGAIOGLK_01363 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
CGAIOGLK_01364 1.1e-38 yajC U Preprotein translocase subunit YajC
CGAIOGLK_01365 1.2e-74 yrzE S Protein of unknown function (DUF3792)
CGAIOGLK_01366 2.2e-114 yrbG S membrane
CGAIOGLK_01367 1.7e-269 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CGAIOGLK_01368 3e-47 yrzD S Post-transcriptional regulator
CGAIOGLK_01369 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CGAIOGLK_01370 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
CGAIOGLK_01371 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
CGAIOGLK_01372 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
CGAIOGLK_01373 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CGAIOGLK_01374 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CGAIOGLK_01375 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CGAIOGLK_01376 3.9e-263 lytH 3.5.1.28 M COG3103 SH3 domain protein
CGAIOGLK_01378 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
CGAIOGLK_01379 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CGAIOGLK_01380 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
CGAIOGLK_01381 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
CGAIOGLK_01382 1.2e-70 cymR K Transcriptional regulator
CGAIOGLK_01383 1.4e-212 iscS 2.8.1.7 E Cysteine desulfurase
CGAIOGLK_01384 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CGAIOGLK_01385 1.4e-15 S COG0457 FOG TPR repeat
CGAIOGLK_01386 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CGAIOGLK_01387 1.8e-83 yrrD S protein conserved in bacteria
CGAIOGLK_01388 9.8e-31 yrzR
CGAIOGLK_01389 8e-08 S Protein of unknown function (DUF3918)
CGAIOGLK_01390 7.6e-107 glnP P ABC transporter
CGAIOGLK_01391 3.6e-109 gluC P ABC transporter
CGAIOGLK_01392 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
CGAIOGLK_01393 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
CGAIOGLK_01394 2.7e-170 yrrI S AI-2E family transporter
CGAIOGLK_01395 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CGAIOGLK_01396 1.7e-41 yrzL S Belongs to the UPF0297 family
CGAIOGLK_01397 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CGAIOGLK_01398 1.2e-45 yrzB S Belongs to the UPF0473 family
CGAIOGLK_01399 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CGAIOGLK_01400 5.9e-120 yrrM 2.1.1.104 S O-methyltransferase
CGAIOGLK_01401 1.9e-172 yegQ O Peptidase U32
CGAIOGLK_01402 2.7e-246 yegQ O COG0826 Collagenase and related proteases
CGAIOGLK_01403 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
CGAIOGLK_01404 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CGAIOGLK_01405 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
CGAIOGLK_01406 6.1e-62 yrrS S Protein of unknown function (DUF1510)
CGAIOGLK_01407 1e-25 yrzA S Protein of unknown function (DUF2536)
CGAIOGLK_01408 8.4e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
CGAIOGLK_01409 1.6e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CGAIOGLK_01410 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
CGAIOGLK_01411 2.6e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
CGAIOGLK_01412 4.6e-35 yrhC S YrhC-like protein
CGAIOGLK_01413 4.1e-78 yrhD S Protein of unknown function (DUF1641)
CGAIOGLK_01414 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
CGAIOGLK_01415 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
CGAIOGLK_01417 1.8e-142 focA P Formate nitrite
CGAIOGLK_01420 1.9e-95 yrhH Q methyltransferase
CGAIOGLK_01421 4.8e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
CGAIOGLK_01422 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
CGAIOGLK_01423 1.4e-44 yrhK S YrhK-like protein
CGAIOGLK_01424 0.0 yrhL I Acyltransferase family
CGAIOGLK_01425 2.5e-150 rsiV S Protein of unknown function (DUF3298)
CGAIOGLK_01426 1.2e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
CGAIOGLK_01427 1.6e-149 yrhO K Archaeal transcriptional regulator TrmB
CGAIOGLK_01428 1.1e-105 yrhP E LysE type translocator
CGAIOGLK_01429 6.6e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
CGAIOGLK_01430 0.0 levR K PTS system fructose IIA component
CGAIOGLK_01431 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
CGAIOGLK_01432 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
CGAIOGLK_01433 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
CGAIOGLK_01434 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
CGAIOGLK_01435 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
CGAIOGLK_01436 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
CGAIOGLK_01437 3.9e-198 adhA 1.1.1.1 C alcohol dehydrogenase
CGAIOGLK_01438 1e-27 yphJ 4.1.1.44 S peroxiredoxin activity
CGAIOGLK_01439 4.3e-47 yraB K helix_turn_helix, mercury resistance
CGAIOGLK_01440 2.5e-49 yraD M Spore coat protein
CGAIOGLK_01441 7.5e-26 yraE
CGAIOGLK_01442 6.5e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
CGAIOGLK_01443 3.2e-62 yraF M Spore coat protein
CGAIOGLK_01444 1.5e-36 yraG
CGAIOGLK_01445 1.1e-65 E Glyoxalase-like domain
CGAIOGLK_01446 2.4e-61 T sh3 domain protein
CGAIOGLK_01447 1.7e-60 T sh3 domain protein
CGAIOGLK_01448 1.5e-152 S Alpha beta hydrolase
CGAIOGLK_01449 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CGAIOGLK_01450 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
CGAIOGLK_01451 1e-204 yraM S PrpF protein
CGAIOGLK_01452 3.4e-163 yraN K Transcriptional regulator
CGAIOGLK_01453 3.6e-225 yraO C Citrate transporter
CGAIOGLK_01454 5.1e-179 yrpG C Aldo/keto reductase family
CGAIOGLK_01455 1.2e-91 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
CGAIOGLK_01456 6.2e-113 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
CGAIOGLK_01458 4.8e-123 yrpD S Domain of unknown function, YrpD
CGAIOGLK_01459 6.9e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
CGAIOGLK_01460 6.4e-193 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
CGAIOGLK_01461 1.1e-163 aadK G Streptomycin adenylyltransferase
CGAIOGLK_01462 2.7e-88 yrdA S DinB family
CGAIOGLK_01463 9.8e-54 S Protein of unknown function (DUF2568)
CGAIOGLK_01464 1e-99 yrdC 3.5.1.19 Q Isochorismatase family
CGAIOGLK_01465 3.1e-10 K Acetyltransferase (GNAT) family
CGAIOGLK_01466 2.8e-227 cypA C Cytochrome P450
CGAIOGLK_01467 5e-44 yrdF K ribonuclease inhibitor
CGAIOGLK_01468 6.3e-79 bkdR K helix_turn_helix ASNC type
CGAIOGLK_01469 2.8e-137 azlC E AzlC protein
CGAIOGLK_01470 2.1e-49 azlD E Branched-chain amino acid transport protein (AzlD)
CGAIOGLK_01471 8.6e-227 brnQ E Component of the transport system for branched-chain amino acids
CGAIOGLK_01472 3.2e-161 gltR K LysR substrate binding domain
CGAIOGLK_01473 2.7e-61 yodA S tautomerase
CGAIOGLK_01474 2.5e-156 czcD P COG1230 Co Zn Cd efflux system component
CGAIOGLK_01475 1.3e-198 trkA P Oxidoreductase
CGAIOGLK_01476 8.6e-159 yrdQ K Transcriptional regulator
CGAIOGLK_01477 2.7e-169 yrdR EG EamA-like transporter family
CGAIOGLK_01478 1.1e-15 S YrzO-like protein
CGAIOGLK_01479 1.9e-234 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
CGAIOGLK_01480 2.6e-82 bltD 2.3.1.57 K FR47-like protein
CGAIOGLK_01481 3.5e-211 blt EGP Major facilitator Superfamily
CGAIOGLK_01482 1e-148 bltR K helix_turn_helix, mercury resistance
CGAIOGLK_01484 4.9e-107 yrkC G Cupin domain
CGAIOGLK_01485 7.8e-39 yrkD S protein conserved in bacteria
CGAIOGLK_01486 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
CGAIOGLK_01487 3.9e-96 yrkF OP Belongs to the sulfur carrier protein TusA family
CGAIOGLK_01488 8.4e-207 yrkH P Rhodanese Homology Domain
CGAIOGLK_01489 1.2e-35 yrkI O Belongs to the sulfur carrier protein TusA family
CGAIOGLK_01490 8.6e-110 yrkJ S membrane transporter protein
CGAIOGLK_01491 3.9e-164 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
CGAIOGLK_01492 3.7e-217 mepA V Multidrug transporter MatE
CGAIOGLK_01493 3.3e-113 tetR3 K Transcriptional regulator
CGAIOGLK_01494 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CGAIOGLK_01495 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
CGAIOGLK_01496 2.3e-133 yqeB
CGAIOGLK_01497 2.5e-169 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
CGAIOGLK_01498 6.7e-105 yqeD S SNARE associated Golgi protein
CGAIOGLK_01499 4.6e-132 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
CGAIOGLK_01500 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
CGAIOGLK_01502 5.3e-95 yqeG S hydrolase of the HAD superfamily
CGAIOGLK_01503 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
CGAIOGLK_01504 1e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CGAIOGLK_01505 6.2e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
CGAIOGLK_01506 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CGAIOGLK_01507 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
CGAIOGLK_01508 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CGAIOGLK_01509 6.5e-139 yqeM Q Methyltransferase
CGAIOGLK_01510 3.9e-145 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CGAIOGLK_01511 1.8e-102 wza L COG1555 DNA uptake protein and related DNA-binding proteins
CGAIOGLK_01512 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
CGAIOGLK_01513 0.0 comEC S Competence protein ComEC
CGAIOGLK_01514 4.1e-15 S YqzM-like protein
CGAIOGLK_01515 1.9e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
CGAIOGLK_01516 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
CGAIOGLK_01517 8.6e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CGAIOGLK_01518 1.5e-222 spoIIP M stage II sporulation protein P
CGAIOGLK_01519 1.1e-53 yqxA S Protein of unknown function (DUF3679)
CGAIOGLK_01520 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CGAIOGLK_01521 2e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
CGAIOGLK_01522 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CGAIOGLK_01523 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CGAIOGLK_01524 0.0 dnaK O Heat shock 70 kDa protein
CGAIOGLK_01525 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CGAIOGLK_01526 5.4e-175 prmA J Methylates ribosomal protein L11
CGAIOGLK_01527 3.6e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CGAIOGLK_01528 6.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
CGAIOGLK_01529 1.4e-157 yqeW P COG1283 Na phosphate symporter
CGAIOGLK_01530 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
CGAIOGLK_01531 1.4e-64 yqeY S Yqey-like protein
CGAIOGLK_01532 9.1e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
CGAIOGLK_01533 4.3e-122 yqfA S UPF0365 protein
CGAIOGLK_01534 3.7e-22 yqfB
CGAIOGLK_01535 2.7e-45 yqfC S sporulation protein YqfC
CGAIOGLK_01536 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
CGAIOGLK_01537 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
CGAIOGLK_01539 0.0 yqfF S membrane-associated HD superfamily hydrolase
CGAIOGLK_01540 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CGAIOGLK_01541 3.5e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
CGAIOGLK_01542 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
CGAIOGLK_01543 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CGAIOGLK_01544 8.4e-19 S YqzL-like protein
CGAIOGLK_01545 6.3e-145 recO L Involved in DNA repair and RecF pathway recombination
CGAIOGLK_01546 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
CGAIOGLK_01547 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
CGAIOGLK_01548 4.5e-112 ccpN K CBS domain
CGAIOGLK_01549 8.4e-148 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
CGAIOGLK_01550 4.5e-88 yaiI S Belongs to the UPF0178 family
CGAIOGLK_01551 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CGAIOGLK_01552 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CGAIOGLK_01553 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
CGAIOGLK_01554 4e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
CGAIOGLK_01555 1.2e-208 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CGAIOGLK_01556 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CGAIOGLK_01557 2.5e-21 yqfQ S YqfQ-like protein
CGAIOGLK_01558 6.5e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CGAIOGLK_01559 2e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CGAIOGLK_01560 2.1e-36 yqfT S Protein of unknown function (DUF2624)
CGAIOGLK_01561 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
CGAIOGLK_01562 1.9e-77 zur P Belongs to the Fur family
CGAIOGLK_01563 2.7e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
CGAIOGLK_01564 4.3e-62 yqfX S membrane
CGAIOGLK_01565 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CGAIOGLK_01566 2.6e-46 yqfZ M LysM domain
CGAIOGLK_01567 3.9e-131 yqgB S Protein of unknown function (DUF1189)
CGAIOGLK_01568 4e-73 yqgC S protein conserved in bacteria
CGAIOGLK_01569 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
CGAIOGLK_01570 2.5e-231 yqgE EGP Major facilitator superfamily
CGAIOGLK_01571 0.0 pbpA 3.4.16.4 M penicillin-binding protein
CGAIOGLK_01572 3.4e-150 pstS P Phosphate
CGAIOGLK_01573 7.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
CGAIOGLK_01574 4.4e-158 pstA P Phosphate transport system permease
CGAIOGLK_01575 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CGAIOGLK_01576 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CGAIOGLK_01577 7.3e-72 yqzC S YceG-like family
CGAIOGLK_01578 9.2e-51 yqzD
CGAIOGLK_01580 2e-197 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
CGAIOGLK_01581 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CGAIOGLK_01582 2.5e-103 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CGAIOGLK_01583 2.5e-09 yqgO
CGAIOGLK_01584 8.9e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
CGAIOGLK_01585 3.1e-33 yqgQ S Protein conserved in bacteria
CGAIOGLK_01586 5.2e-181 glcK 2.7.1.2 G Glucokinase
CGAIOGLK_01587 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
CGAIOGLK_01588 2.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
CGAIOGLK_01589 2.7e-199 yqgU
CGAIOGLK_01590 6.9e-50 yqgV S Thiamine-binding protein
CGAIOGLK_01591 1.2e-22 yqgW S Protein of unknown function (DUF2759)
CGAIOGLK_01592 1.2e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
CGAIOGLK_01593 1.8e-37 yqgY S Protein of unknown function (DUF2626)
CGAIOGLK_01594 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
CGAIOGLK_01596 3.5e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CGAIOGLK_01597 1.8e-237 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
CGAIOGLK_01598 7.2e-175 corA P Mg2 transporter protein
CGAIOGLK_01599 1.6e-07 ylbB S IMP dehydrogenase activity
CGAIOGLK_01600 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CGAIOGLK_01601 2.3e-174 comGB NU COG1459 Type II secretory pathway, component PulF
CGAIOGLK_01602 1.4e-47 comGC U Required for transformation and DNA binding
CGAIOGLK_01603 3.5e-68 gspH NU protein transport across the cell outer membrane
CGAIOGLK_01604 6.9e-59 comGE
CGAIOGLK_01605 2e-45 comGF U Putative Competence protein ComGF
CGAIOGLK_01606 8.8e-44 S ComG operon protein 7
CGAIOGLK_01607 2.6e-25 yqzE S YqzE-like protein
CGAIOGLK_01608 1.1e-52 yqzG S Protein of unknown function (DUF3889)
CGAIOGLK_01609 1.3e-113 yqxM
CGAIOGLK_01610 2.5e-58 sipW 3.4.21.89 U Signal peptidase
CGAIOGLK_01611 1.9e-141 tasA S Cell division protein FtsN
CGAIOGLK_01612 1e-54 sinR K transcriptional
CGAIOGLK_01613 1.2e-24 sinI S Anti-repressor SinI
CGAIOGLK_01614 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
CGAIOGLK_01615 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
CGAIOGLK_01616 1.5e-205 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
CGAIOGLK_01617 1.7e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CGAIOGLK_01618 1.4e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CGAIOGLK_01619 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
CGAIOGLK_01620 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
CGAIOGLK_01621 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
CGAIOGLK_01622 3.4e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
CGAIOGLK_01623 2.8e-48 yqhP
CGAIOGLK_01624 8e-174 yqhQ S Protein of unknown function (DUF1385)
CGAIOGLK_01625 2.3e-93 yqhR S Conserved membrane protein YqhR
CGAIOGLK_01626 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
CGAIOGLK_01627 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
CGAIOGLK_01628 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CGAIOGLK_01629 7.9e-37 yqhV S Protein of unknown function (DUF2619)
CGAIOGLK_01630 4e-170 spoIIIAA S stage III sporulation protein AA
CGAIOGLK_01631 1.1e-84 spoIIIAB S Stage III sporulation protein
CGAIOGLK_01632 7.6e-29 spoIIIAC S stage III sporulation protein AC
CGAIOGLK_01633 2.3e-58 spoIIIAD S Stage III sporulation protein AD
CGAIOGLK_01634 1.3e-197 spoIIIAE S stage III sporulation protein AE
CGAIOGLK_01635 4.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
CGAIOGLK_01636 8.5e-109 spoIIIAG S stage III sporulation protein AG
CGAIOGLK_01637 9.9e-91 spoIIIAH S SpoIIIAH-like protein
CGAIOGLK_01638 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CGAIOGLK_01639 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
CGAIOGLK_01640 2.1e-67 yqhY S protein conserved in bacteria
CGAIOGLK_01641 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CGAIOGLK_01642 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CGAIOGLK_01643 3.8e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CGAIOGLK_01644 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CGAIOGLK_01645 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CGAIOGLK_01646 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CGAIOGLK_01647 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
CGAIOGLK_01648 1.7e-78 argR K Regulates arginine biosynthesis genes
CGAIOGLK_01649 0.0 recN L May be involved in recombinational repair of damaged DNA
CGAIOGLK_01650 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
CGAIOGLK_01651 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
CGAIOGLK_01653 2.5e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
CGAIOGLK_01654 6e-27
CGAIOGLK_01655 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
CGAIOGLK_01656 1e-128 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
CGAIOGLK_01657 5.9e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
CGAIOGLK_01658 1.2e-155 hbdA 1.1.1.157 I Dehydrogenase
CGAIOGLK_01659 6.3e-210 mmgC I acyl-CoA dehydrogenase
CGAIOGLK_01660 1.9e-206 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
CGAIOGLK_01661 6.3e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
CGAIOGLK_01662 1.6e-163 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CGAIOGLK_01663 4.4e-33 yqzF S Protein of unknown function (DUF2627)
CGAIOGLK_01664 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
CGAIOGLK_01665 1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
CGAIOGLK_01666 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
CGAIOGLK_01667 2.7e-202 buk 2.7.2.7 C Belongs to the acetokinase family
CGAIOGLK_01668 9.8e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
CGAIOGLK_01669 7.2e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
CGAIOGLK_01670 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CGAIOGLK_01671 3.2e-226 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CGAIOGLK_01672 2.9e-151 bmrR K helix_turn_helix, mercury resistance
CGAIOGLK_01673 1.4e-207 norA EGP Major facilitator Superfamily
CGAIOGLK_01674 2.6e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
CGAIOGLK_01675 9.3e-77 yqiW S Belongs to the UPF0403 family
CGAIOGLK_01676 1.8e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
CGAIOGLK_01677 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
CGAIOGLK_01678 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
CGAIOGLK_01679 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
CGAIOGLK_01680 6.8e-98 yqjB S protein conserved in bacteria
CGAIOGLK_01682 4.2e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
CGAIOGLK_01683 1.3e-287 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
CGAIOGLK_01684 1.4e-201 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
CGAIOGLK_01685 2e-103 yqjF S Uncharacterized conserved protein (COG2071)
CGAIOGLK_01686 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CGAIOGLK_01687 1e-23 yqzJ
CGAIOGLK_01688 1.6e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CGAIOGLK_01689 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CGAIOGLK_01690 5.2e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CGAIOGLK_01691 3.2e-172 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CGAIOGLK_01692 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CGAIOGLK_01693 6.2e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CGAIOGLK_01694 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
CGAIOGLK_01695 0.0 rocB E arginine degradation protein
CGAIOGLK_01696 5.6e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CGAIOGLK_01697 5.4e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
CGAIOGLK_01698 3.5e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
CGAIOGLK_01699 4.4e-263 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
CGAIOGLK_01700 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
CGAIOGLK_01701 8.8e-71 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CGAIOGLK_01703 1.4e-223 yqjV G Major Facilitator Superfamily
CGAIOGLK_01705 1e-237 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CGAIOGLK_01706 5.7e-50 S YolD-like protein
CGAIOGLK_01707 3.6e-87 yqjY K acetyltransferase
CGAIOGLK_01708 3.5e-55 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
CGAIOGLK_01709 1.9e-81 yqkA K GrpB protein
CGAIOGLK_01710 3.7e-102 yqkA K GrpB protein
CGAIOGLK_01711 2.8e-54 yqkB S Belongs to the HesB IscA family
CGAIOGLK_01712 9.4e-39 yqkC S Protein of unknown function (DUF2552)
CGAIOGLK_01713 1.6e-171 yqkD S COG1073 Hydrolases of the alpha beta superfamily
CGAIOGLK_01714 1.8e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
CGAIOGLK_01716 2.6e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
CGAIOGLK_01717 1.1e-220 yqxK 3.6.4.12 L DNA helicase
CGAIOGLK_01718 4.5e-58 ansR K Transcriptional regulator
CGAIOGLK_01719 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
CGAIOGLK_01720 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
CGAIOGLK_01721 3.5e-234 mleN C Na H antiporter
CGAIOGLK_01722 5.5e-242 mleA 1.1.1.38 C malic enzyme
CGAIOGLK_01723 1.9e-30 yqkK
CGAIOGLK_01724 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
CGAIOGLK_01725 2.4e-80 fur P Belongs to the Fur family
CGAIOGLK_01726 1.4e-36 S Protein of unknown function (DUF4227)
CGAIOGLK_01727 2.6e-166 xerD L recombinase XerD
CGAIOGLK_01728 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
CGAIOGLK_01729 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CGAIOGLK_01730 2.4e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
CGAIOGLK_01731 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
CGAIOGLK_01732 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
CGAIOGLK_01733 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CGAIOGLK_01734 9.6e-112 spoVAA S Stage V sporulation protein AA
CGAIOGLK_01735 1e-67 spoVAB S Stage V sporulation protein AB
CGAIOGLK_01736 2.3e-78 spoVAC S stage V sporulation protein AC
CGAIOGLK_01737 4.5e-191 spoVAD I Stage V sporulation protein AD
CGAIOGLK_01738 2.2e-57 spoVAEB S stage V sporulation protein
CGAIOGLK_01739 1.4e-110 spoVAEA S stage V sporulation protein
CGAIOGLK_01740 1.4e-273 spoVAF EG Stage V sporulation protein AF
CGAIOGLK_01741 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CGAIOGLK_01742 1.3e-149 ypuA S Secreted protein
CGAIOGLK_01743 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CGAIOGLK_01745 3.6e-13 S PAP2 superfamily
CGAIOGLK_01746 1.6e-31 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
CGAIOGLK_01747 3.4e-100 sipT 3.4.21.89 U Belongs to the peptidase S26 family
CGAIOGLK_01748 7.8e-55 ypuD
CGAIOGLK_01749 2.9e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CGAIOGLK_01750 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
CGAIOGLK_01751 4.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CGAIOGLK_01752 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
CGAIOGLK_01753 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CGAIOGLK_01754 2.5e-92 ypuF S Domain of unknown function (DUF309)
CGAIOGLK_01755 1.3e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CGAIOGLK_01756 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CGAIOGLK_01757 7.6e-97 ypuI S Protein of unknown function (DUF3907)
CGAIOGLK_01758 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
CGAIOGLK_01759 3.5e-103 spmA S Spore maturation protein
CGAIOGLK_01760 1.9e-87 spmB S Spore maturation protein
CGAIOGLK_01761 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CGAIOGLK_01762 4.8e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
CGAIOGLK_01763 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
CGAIOGLK_01764 8.8e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
CGAIOGLK_01765 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CGAIOGLK_01766 0.0 resE 2.7.13.3 T Histidine kinase
CGAIOGLK_01767 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
CGAIOGLK_01768 7.5e-192 rsiX
CGAIOGLK_01769 5.9e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
CGAIOGLK_01770 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CGAIOGLK_01771 2.7e-84 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CGAIOGLK_01772 4.7e-41 fer C Ferredoxin
CGAIOGLK_01773 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
CGAIOGLK_01774 9.2e-286 recQ 3.6.4.12 L DNA helicase
CGAIOGLK_01775 1.1e-99 ypbD S metal-dependent membrane protease
CGAIOGLK_01776 2.2e-78 ypbE M Lysin motif
CGAIOGLK_01777 8.2e-81 ypbF S Protein of unknown function (DUF2663)
CGAIOGLK_01778 6.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
CGAIOGLK_01779 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
CGAIOGLK_01780 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
CGAIOGLK_01781 8.1e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
CGAIOGLK_01782 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
CGAIOGLK_01783 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
CGAIOGLK_01784 1.9e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
CGAIOGLK_01785 2.3e-111 ypfA M Flagellar protein YcgR
CGAIOGLK_01786 1.8e-23 S Family of unknown function (DUF5359)
CGAIOGLK_01787 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
CGAIOGLK_01788 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
CGAIOGLK_01789 2.6e-186 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CGAIOGLK_01790 1e-07 S YpzI-like protein
CGAIOGLK_01791 1.3e-102 yphA
CGAIOGLK_01792 2.5e-161 seaA S YIEGIA protein
CGAIOGLK_01793 7.9e-28 ypzH
CGAIOGLK_01794 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
CGAIOGLK_01795 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
CGAIOGLK_01796 1.6e-18 yphE S Protein of unknown function (DUF2768)
CGAIOGLK_01797 1e-136 yphF
CGAIOGLK_01798 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CGAIOGLK_01799 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CGAIOGLK_01800 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
CGAIOGLK_01801 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
CGAIOGLK_01802 3.7e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
CGAIOGLK_01803 4.2e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
CGAIOGLK_01804 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CGAIOGLK_01805 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
CGAIOGLK_01806 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
CGAIOGLK_01807 1.2e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CGAIOGLK_01808 2.2e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CGAIOGLK_01809 3e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
CGAIOGLK_01810 5.2e-292 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CGAIOGLK_01811 1.2e-175 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CGAIOGLK_01812 2.8e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
CGAIOGLK_01813 1.4e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
CGAIOGLK_01814 1.5e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CGAIOGLK_01815 4.7e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
CGAIOGLK_01816 3.2e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CGAIOGLK_01817 1.7e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
CGAIOGLK_01818 3.4e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
CGAIOGLK_01819 4.1e-234 S COG0457 FOG TPR repeat
CGAIOGLK_01820 1.1e-98 ypiB S Belongs to the UPF0302 family
CGAIOGLK_01821 1.4e-75 ypiF S Protein of unknown function (DUF2487)
CGAIOGLK_01822 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
CGAIOGLK_01823 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
CGAIOGLK_01824 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
CGAIOGLK_01825 2e-98 ypjA S membrane
CGAIOGLK_01826 5.1e-142 ypjB S sporulation protein
CGAIOGLK_01827 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
CGAIOGLK_01828 5.9e-55 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
CGAIOGLK_01829 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CGAIOGLK_01830 6.5e-72 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
CGAIOGLK_01831 5.8e-129 bshB1 S proteins, LmbE homologs
CGAIOGLK_01832 1.4e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
CGAIOGLK_01833 2e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CGAIOGLK_01834 1.3e-182 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CGAIOGLK_01835 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
CGAIOGLK_01836 4.4e-155 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CGAIOGLK_01837 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CGAIOGLK_01838 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
CGAIOGLK_01839 4.1e-22 ypmA S Protein of unknown function (DUF4264)
CGAIOGLK_01840 2.2e-79 ypmB S protein conserved in bacteria
CGAIOGLK_01841 7.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
CGAIOGLK_01842 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
CGAIOGLK_01843 5.7e-129 dnaD L DNA replication protein DnaD
CGAIOGLK_01844 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CGAIOGLK_01845 1.8e-92 ypoC
CGAIOGLK_01846 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
CGAIOGLK_01847 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CGAIOGLK_01848 7e-186 yppC S Protein of unknown function (DUF2515)
CGAIOGLK_01851 5.7e-11 yppE S Bacterial domain of unknown function (DUF1798)
CGAIOGLK_01853 1e-47 yppG S YppG-like protein
CGAIOGLK_01854 1.9e-71 hspX O Belongs to the small heat shock protein (HSP20) family
CGAIOGLK_01855 2.5e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
CGAIOGLK_01856 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
CGAIOGLK_01857 5.6e-236 yprB L RNase_H superfamily
CGAIOGLK_01858 1.4e-87 ypsA S Belongs to the UPF0398 family
CGAIOGLK_01859 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CGAIOGLK_01860 5.1e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
CGAIOGLK_01862 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
CGAIOGLK_01863 2.3e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CGAIOGLK_01864 1.4e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CGAIOGLK_01865 2e-186 ptxS K transcriptional
CGAIOGLK_01866 7.1e-186 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
CGAIOGLK_01867 1.3e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
CGAIOGLK_01868 1.9e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
CGAIOGLK_01869 3.9e-292 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CGAIOGLK_01870 1.3e-97 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CGAIOGLK_01871 1.1e-226 pbuX F xanthine
CGAIOGLK_01872 1.1e-206 bcsA Q Naringenin-chalcone synthase
CGAIOGLK_01873 5.1e-87 ypbQ S protein conserved in bacteria
CGAIOGLK_01875 0.0 ypbR S Dynamin family
CGAIOGLK_01876 1e-38 ypbS S Protein of unknown function (DUF2533)
CGAIOGLK_01877 2e-07
CGAIOGLK_01878 4.4e-166 polA 2.7.7.7 L 5'3' exonuclease
CGAIOGLK_01880 1.8e-66 rnhA 3.1.26.4 L Ribonuclease
CGAIOGLK_01881 7.7e-106 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CGAIOGLK_01882 1.7e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
CGAIOGLK_01883 3e-29 ypeQ S Zinc-finger
CGAIOGLK_01884 1.4e-30 S Protein of unknown function (DUF2564)
CGAIOGLK_01885 3.8e-16 degR
CGAIOGLK_01886 7.9e-31 cspD K Cold-shock protein
CGAIOGLK_01887 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
CGAIOGLK_01888 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CGAIOGLK_01889 5.2e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
CGAIOGLK_01890 9.3e-107 ypgQ S phosphohydrolase
CGAIOGLK_01891 3.4e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
CGAIOGLK_01892 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
CGAIOGLK_01893 1.7e-75 yphP S Belongs to the UPF0403 family
CGAIOGLK_01894 1.4e-144 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
CGAIOGLK_01895 8.6e-113 ypjP S YpjP-like protein
CGAIOGLK_01896 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
CGAIOGLK_01897 7.6e-154 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CGAIOGLK_01898 1.6e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CGAIOGLK_01899 1.1e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
CGAIOGLK_01900 4.2e-110 hlyIII S protein, Hemolysin III
CGAIOGLK_01901 6.1e-185 pspF K Transcriptional regulator
CGAIOGLK_01902 9.7e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CGAIOGLK_01903 3.1e-40 ypmP S Protein of unknown function (DUF2535)
CGAIOGLK_01904 4.6e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
CGAIOGLK_01905 1.1e-136 ypmR E GDSL-like Lipase/Acylhydrolase
CGAIOGLK_01906 1.1e-98 ypmS S protein conserved in bacteria
CGAIOGLK_01907 1.2e-28 ypmT S Uncharacterized ympT
CGAIOGLK_01908 4.5e-223 mepA V MATE efflux family protein
CGAIOGLK_01909 1.6e-70 ypoP K transcriptional
CGAIOGLK_01910 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CGAIOGLK_01911 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
CGAIOGLK_01912 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
CGAIOGLK_01913 5.2e-212 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
CGAIOGLK_01914 2.4e-186 cgeB S Spore maturation protein
CGAIOGLK_01915 1.2e-65 cgeA
CGAIOGLK_01916 5.9e-38 cgeC
CGAIOGLK_01917 2.9e-256 cgeD M maturation of the outermost layer of the spore
CGAIOGLK_01918 1.8e-144 yiiD K acetyltransferase
CGAIOGLK_01920 3.4e-247 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CGAIOGLK_01921 7.1e-124 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CGAIOGLK_01922 2.8e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
CGAIOGLK_01923 9.3e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
CGAIOGLK_01924 6.7e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
CGAIOGLK_01925 2e-277 kamA 5.4.3.2 E lysine 2,3-aminomutase
CGAIOGLK_01926 2.9e-47 yokU S YokU-like protein, putative antitoxin
CGAIOGLK_01927 1.4e-36 yozE S Belongs to the UPF0346 family
CGAIOGLK_01928 1.6e-123 yodN
CGAIOGLK_01930 2.8e-24 yozD S YozD-like protein
CGAIOGLK_01931 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
CGAIOGLK_01932 3.6e-54 yodL S YodL-like
CGAIOGLK_01933 5.3e-09
CGAIOGLK_01934 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
CGAIOGLK_01935 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
CGAIOGLK_01936 1.5e-23 yodI
CGAIOGLK_01937 2.4e-127 yodH Q Methyltransferase
CGAIOGLK_01938 6.3e-252 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
CGAIOGLK_01939 6.6e-268 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGAIOGLK_01940 6.2e-28 S Protein of unknown function (DUF3311)
CGAIOGLK_01941 1.3e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
CGAIOGLK_01942 3.8e-113 mhqD S Carboxylesterase
CGAIOGLK_01943 4.8e-108 yodC C nitroreductase
CGAIOGLK_01944 4.4e-55 yodB K transcriptional
CGAIOGLK_01945 8e-64 yodA S tautomerase
CGAIOGLK_01946 1.2e-207 gntP EG COG2610 H gluconate symporter and related permeases
CGAIOGLK_01947 3.4e-09
CGAIOGLK_01948 5.5e-59 yozR S COG0071 Molecular chaperone (small heat shock protein)
CGAIOGLK_01949 1.2e-160 rarD S -transporter
CGAIOGLK_01950 1.5e-43
CGAIOGLK_01951 2.2e-60 yojF S Protein of unknown function (DUF1806)
CGAIOGLK_01952 2.1e-125 yojG S deacetylase
CGAIOGLK_01953 3.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CGAIOGLK_01954 1.6e-244 norM V Multidrug efflux pump
CGAIOGLK_01956 5.8e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CGAIOGLK_01957 4.1e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
CGAIOGLK_01958 6.7e-197 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
CGAIOGLK_01959 1.7e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CGAIOGLK_01960 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
CGAIOGLK_01961 0.0 yojO P Von Willebrand factor
CGAIOGLK_01962 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
CGAIOGLK_01963 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
CGAIOGLK_01964 5.1e-168 yocS S -transporter
CGAIOGLK_01965 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
CGAIOGLK_01966 6e-165 sodA 1.15.1.1 P Superoxide dismutase
CGAIOGLK_01967 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
CGAIOGLK_01968 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
CGAIOGLK_01969 2.7e-31 yozC
CGAIOGLK_01970 4.2e-56 yozO S Bacterial PH domain
CGAIOGLK_01971 1.9e-36 yocN
CGAIOGLK_01972 3.2e-40 yozN
CGAIOGLK_01973 3.1e-86 yocM O Belongs to the small heat shock protein (HSP20) family
CGAIOGLK_01974 2.8e-32
CGAIOGLK_01975 6.4e-54 yocL
CGAIOGLK_01976 5.7e-83 dksA T general stress protein
CGAIOGLK_01977 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CGAIOGLK_01978 0.0 recQ 3.6.4.12 L DNA helicase
CGAIOGLK_01979 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
CGAIOGLK_01980 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CGAIOGLK_01981 7.1e-198 desK 2.7.13.3 T Histidine kinase
CGAIOGLK_01982 5.3e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
CGAIOGLK_01983 1.4e-186 yocD 3.4.17.13 V peptidase S66
CGAIOGLK_01984 1.5e-91 yocC
CGAIOGLK_01985 7.3e-141
CGAIOGLK_01986 1.5e-92 yozB S membrane
CGAIOGLK_01987 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
CGAIOGLK_01988 1e-51 czrA K transcriptional
CGAIOGLK_01989 1.1e-90 yobW
CGAIOGLK_01990 6.4e-176 yobV K WYL domain
CGAIOGLK_01991 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
CGAIOGLK_01992 2.1e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
CGAIOGLK_01993 3e-99 yobS K Transcriptional regulator
CGAIOGLK_01994 8.2e-142 yobR 2.3.1.1 J FR47-like protein
CGAIOGLK_01995 1.1e-135 yobQ K helix_turn_helix, arabinose operon control protein
CGAIOGLK_01996 9.3e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
CGAIOGLK_01997 0.0 yobO M Pectate lyase superfamily protein
CGAIOGLK_01998 1.7e-276 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
CGAIOGLK_01999 3e-91 yokH G SMI1 / KNR4 family
CGAIOGLK_02000 6.5e-10 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
CGAIOGLK_02001 9.7e-19
CGAIOGLK_02003 3.5e-46
CGAIOGLK_02005 5.5e-33 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CGAIOGLK_02006 2.3e-27 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CGAIOGLK_02007 2.3e-79 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CGAIOGLK_02009 9.2e-206 S aspartate phosphatase
CGAIOGLK_02013 1.1e-61 yoqH M LysM domain
CGAIOGLK_02015 1.3e-28 S Bacillus cereus group antimicrobial protein
CGAIOGLK_02022 8.7e-32 isp O Subtilase family
CGAIOGLK_02023 1.1e-116
CGAIOGLK_02025 7.5e-78 mepB S MepB protein
CGAIOGLK_02028 1.7e-54 K Helix-turn-helix
CGAIOGLK_02029 1.4e-37 S TM2 domain
CGAIOGLK_02030 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
CGAIOGLK_02031 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
CGAIOGLK_02034 8.5e-165 bla 3.5.2.6 V beta-lactamase
CGAIOGLK_02035 5.2e-113 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
CGAIOGLK_02036 1.8e-77 yoaW
CGAIOGLK_02037 9.6e-158 yijE EG EamA-like transporter family
CGAIOGLK_02038 1.6e-157 yoaU K LysR substrate binding domain
CGAIOGLK_02039 3.7e-148 yoaT S Protein of unknown function (DUF817)
CGAIOGLK_02040 4.4e-30 yozG K Transcriptional regulator
CGAIOGLK_02041 2.8e-74 yoaS S Protein of unknown function (DUF2975)
CGAIOGLK_02042 1.8e-170 yoaR V vancomycin resistance protein
CGAIOGLK_02043 3.3e-86
CGAIOGLK_02045 2.7e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
CGAIOGLK_02046 2.2e-142 yoaP 3.1.3.18 K YoaP-like
CGAIOGLK_02048 3.8e-234 oxdC 4.1.1.2 G Oxalate decarboxylase
CGAIOGLK_02051 1.2e-131 yoqW S Belongs to the SOS response-associated peptidase family
CGAIOGLK_02052 2.5e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
CGAIOGLK_02053 2.6e-110 yoaK S Membrane
CGAIOGLK_02054 1.1e-132 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
CGAIOGLK_02055 8.1e-279 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
CGAIOGLK_02056 8.2e-182 mcpU NT methyl-accepting chemotaxis protein
CGAIOGLK_02057 7.7e-35 S Protein of unknown function (DUF4025)
CGAIOGLK_02058 2.6e-13
CGAIOGLK_02059 6.5e-08 ywlA S Uncharacterised protein family (UPF0715)
CGAIOGLK_02060 1.1e-33 yoaF
CGAIOGLK_02061 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CGAIOGLK_02062 7.5e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CGAIOGLK_02063 5.3e-278 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
CGAIOGLK_02064 1.8e-234 yoaB EGP Major facilitator Superfamily
CGAIOGLK_02065 3.5e-125 3.1.1.3 I Lipase (class 3)
CGAIOGLK_02066 2.4e-240 S Arylsulfotransferase (ASST)
CGAIOGLK_02067 3.6e-91 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CGAIOGLK_02068 1.5e-143 yoxB
CGAIOGLK_02069 9.8e-41 yoxC S Bacterial protein of unknown function (DUF948)
CGAIOGLK_02070 2.4e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CGAIOGLK_02071 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
CGAIOGLK_02072 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CGAIOGLK_02073 3.5e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CGAIOGLK_02074 7.8e-155 gltC K Transcriptional regulator
CGAIOGLK_02075 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
CGAIOGLK_02076 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
CGAIOGLK_02077 7.2e-186 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
CGAIOGLK_02078 1.1e-155 gltR1 K Transcriptional regulator
CGAIOGLK_02079 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
CGAIOGLK_02080 5.1e-34 yoeD G Helix-turn-helix domain
CGAIOGLK_02081 2.2e-96 L Integrase
CGAIOGLK_02083 5.3e-98 yoeB S IseA DL-endopeptidase inhibitor
CGAIOGLK_02084 2.3e-246 yoeA V MATE efflux family protein
CGAIOGLK_02085 7.6e-188 yoxA 5.1.3.3 G Aldose 1-epimerase
CGAIOGLK_02086 6.8e-273 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
CGAIOGLK_02087 2.3e-90 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CGAIOGLK_02088 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CGAIOGLK_02089 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CGAIOGLK_02090 9e-37 yaaB S Domain of unknown function (DUF370)
CGAIOGLK_02091 1.3e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CGAIOGLK_02092 2.4e-33 yaaA S S4 domain
CGAIOGLK_02093 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CGAIOGLK_02094 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CGAIOGLK_02095 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CGAIOGLK_02096 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CGAIOGLK_02097 6.5e-108 jag S single-stranded nucleic acid binding R3H
CGAIOGLK_02098 2.2e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CGAIOGLK_02099 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CGAIOGLK_02100 5.3e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
CGAIOGLK_02101 2.1e-149 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
CGAIOGLK_02102 1.1e-72 S Bacterial PH domain
CGAIOGLK_02103 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
CGAIOGLK_02104 2.1e-149 spo0J K Belongs to the ParB family
CGAIOGLK_02105 1.6e-111 yyaC S Sporulation protein YyaC
CGAIOGLK_02106 1.8e-176 yyaD S Membrane
CGAIOGLK_02107 2.3e-33 yyzM S protein conserved in bacteria
CGAIOGLK_02108 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CGAIOGLK_02109 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CGAIOGLK_02110 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
CGAIOGLK_02111 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CGAIOGLK_02112 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CGAIOGLK_02113 1.4e-141 xth 3.1.11.2 L exodeoxyribonuclease III
CGAIOGLK_02114 4.4e-177 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
CGAIOGLK_02115 2.2e-66 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CGAIOGLK_02116 1.1e-93 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
CGAIOGLK_02117 1.8e-243 EGP Major facilitator superfamily
CGAIOGLK_02118 8e-168 yyaK S CAAX protease self-immunity
CGAIOGLK_02119 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
CGAIOGLK_02120 1.1e-245 tetL EGP Major facilitator Superfamily
CGAIOGLK_02121 3.3e-103 yyaP 1.5.1.3 H RibD C-terminal domain
CGAIOGLK_02122 6.6e-65 yyaQ S YjbR
CGAIOGLK_02123 3.2e-92 yyaR K Acetyltransferase (GNAT) domain
CGAIOGLK_02124 4.2e-96 yyaS S Membrane
CGAIOGLK_02125 1.3e-70 yjcF S Acetyltransferase (GNAT) domain
CGAIOGLK_02126 5.6e-77 yybA 2.3.1.57 K transcriptional
CGAIOGLK_02127 8.1e-125 S Metallo-beta-lactamase superfamily
CGAIOGLK_02128 1.8e-73 yybC
CGAIOGLK_02129 7.7e-79 yjcF S Acetyltransferase (GNAT) domain
CGAIOGLK_02130 6.9e-164 yybE K Transcriptional regulator
CGAIOGLK_02131 2e-217 ynfM EGP Major facilitator Superfamily
CGAIOGLK_02132 1.8e-121 yybG S Pentapeptide repeat-containing protein
CGAIOGLK_02133 2.9e-66 yybH S SnoaL-like domain
CGAIOGLK_02134 2.4e-123
CGAIOGLK_02135 8.2e-110 K TipAS antibiotic-recognition domain
CGAIOGLK_02136 1.1e-239 yybO G COG0477 Permeases of the major facilitator superfamily
CGAIOGLK_02138 5.6e-61
CGAIOGLK_02139 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
CGAIOGLK_02140 7.5e-67 ydeP3 K Transcriptional regulator
CGAIOGLK_02141 3.3e-83 cotF M Spore coat protein
CGAIOGLK_02143 8.3e-160 yybS S membrane
CGAIOGLK_02144 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
CGAIOGLK_02145 2.2e-73 rplI J binds to the 23S rRNA
CGAIOGLK_02146 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CGAIOGLK_02147 5.5e-220 yeaN P COG2807 Cyanate permease
CGAIOGLK_02148 1.9e-15 yycC K YycC-like protein
CGAIOGLK_02150 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
CGAIOGLK_02151 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
CGAIOGLK_02152 3.1e-77 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CGAIOGLK_02153 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CGAIOGLK_02158 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CGAIOGLK_02159 0.0 vicK 2.7.13.3 T Histidine kinase
CGAIOGLK_02160 2.6e-258 yycH S protein conserved in bacteria
CGAIOGLK_02161 1.1e-153 yycI S protein conserved in bacteria
CGAIOGLK_02162 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
CGAIOGLK_02163 8.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CGAIOGLK_02164 1.1e-17 S Peptidase propeptide and YPEB domain
CGAIOGLK_02165 3e-74 S Peptidase propeptide and YPEB domain
CGAIOGLK_02166 3.4e-94 K PFAM response regulator receiver
CGAIOGLK_02167 8.8e-172 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
CGAIOGLK_02168 4.4e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
CGAIOGLK_02169 7.3e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
CGAIOGLK_02170 1.6e-260 rocE E amino acid
CGAIOGLK_02171 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
CGAIOGLK_02173 7.2e-187 S aspartate phosphatase
CGAIOGLK_02174 2e-85 yycN 2.3.1.128 K Acetyltransferase
CGAIOGLK_02175 2.9e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CGAIOGLK_02176 1.5e-206 yycP
CGAIOGLK_02177 1.7e-30 yycQ S Protein of unknown function (DUF2651)
CGAIOGLK_02179 6.7e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
CGAIOGLK_02180 4.4e-68
CGAIOGLK_02181 1.1e-09 S YyzF-like protein
CGAIOGLK_02182 2e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CGAIOGLK_02183 4.4e-107 S Protein of unknown function DUF262
CGAIOGLK_02184 1.8e-55
CGAIOGLK_02185 2.7e-144 hsdBM 2.1.1.72, 3.1.21.4 L Eco57I restriction-modification methylase
CGAIOGLK_02186 4.1e-130 pstIR 2.1.1.72, 3.1.21.4 L BsuBI/PstI restriction endonuclease C-terminus
CGAIOGLK_02187 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
CGAIOGLK_02188 8.6e-12
CGAIOGLK_02189 9.3e-127 yydK K Transcriptional regulator
CGAIOGLK_02190 1.8e-19 bglF G phosphotransferase system
CGAIOGLK_02191 4.1e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CGAIOGLK_02192 1.9e-286 ahpF O Alkyl hydroperoxide reductase
CGAIOGLK_02193 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
CGAIOGLK_02194 1.4e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CGAIOGLK_02195 5.3e-224 gntP EG COG2610 H gluconate symporter and related permeases
CGAIOGLK_02196 1.2e-301 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
CGAIOGLK_02197 7.3e-127 gntR K transcriptional
CGAIOGLK_02198 1.9e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
CGAIOGLK_02199 1.7e-190 yxaB GM Polysaccharide pyruvyl transferase
CGAIOGLK_02200 2.6e-118 yxaC M effector of murein hydrolase
CGAIOGLK_02201 5.2e-50 S LrgA family
CGAIOGLK_02202 7.5e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
CGAIOGLK_02203 4.7e-199 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CGAIOGLK_02204 9.3e-101 yxaF K Transcriptional regulator
CGAIOGLK_02205 3.5e-196 yxaG 1.13.11.24 S AraC-like ligand binding domain
CGAIOGLK_02206 9e-223 P Protein of unknown function (DUF418)
CGAIOGLK_02207 6.9e-75 yxaI S membrane protein domain
CGAIOGLK_02208 5.1e-64 S Family of unknown function (DUF5391)
CGAIOGLK_02209 3.7e-91 S PQQ-like domain
CGAIOGLK_02210 3.1e-30 yxaI S membrane protein domain
CGAIOGLK_02211 7.6e-247 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
CGAIOGLK_02212 3.5e-208 yxbF K Bacterial regulatory proteins, tetR family
CGAIOGLK_02213 2.6e-149 IQ Enoyl-(Acyl carrier protein) reductase
CGAIOGLK_02215 0.0 htpG O Molecular chaperone. Has ATPase activity
CGAIOGLK_02216 1.1e-243 csbC EGP Major facilitator Superfamily
CGAIOGLK_02217 8.3e-48 yxcD S Protein of unknown function (DUF2653)
CGAIOGLK_02219 4.1e-175 iolS C Aldo keto reductase
CGAIOGLK_02220 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
CGAIOGLK_02221 1.8e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CGAIOGLK_02222 3.5e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
CGAIOGLK_02223 5.5e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
CGAIOGLK_02224 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
CGAIOGLK_02225 1.4e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
CGAIOGLK_02226 1.2e-233 iolF EGP Major facilitator Superfamily
CGAIOGLK_02227 6.1e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
CGAIOGLK_02228 3.1e-110 iolH G Xylose isomerase-like TIM barrel
CGAIOGLK_02229 4.3e-46 iolH G Xylose isomerase-like TIM barrel
CGAIOGLK_02230 2.1e-138 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
CGAIOGLK_02231 1.2e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
CGAIOGLK_02232 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CGAIOGLK_02233 2e-180 T PhoQ Sensor
CGAIOGLK_02234 9.4e-141 yxdL V ABC transporter, ATP-binding protein
CGAIOGLK_02235 0.0 yxdM V ABC transporter (permease)
CGAIOGLK_02236 1.5e-58 yxeA S Protein of unknown function (DUF1093)
CGAIOGLK_02237 1.2e-174 fhuD P ABC transporter
CGAIOGLK_02238 8.5e-69
CGAIOGLK_02239 1.9e-16 yxeD
CGAIOGLK_02240 1.3e-20 yxeE
CGAIOGLK_02243 6.8e-150 yidA S hydrolases of the HAD superfamily
CGAIOGLK_02244 7.2e-186 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
CGAIOGLK_02245 3.1e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGAIOGLK_02246 8.9e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CGAIOGLK_02247 1.2e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
CGAIOGLK_02248 2.7e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
CGAIOGLK_02249 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
CGAIOGLK_02250 6.8e-212 yxeP 3.5.1.47 E hydrolase activity
CGAIOGLK_02251 3e-251 yxeQ S MmgE/PrpD family
CGAIOGLK_02252 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
CGAIOGLK_02253 2.6e-152 yxxB S Domain of Unknown Function (DUF1206)
CGAIOGLK_02254 2.3e-173 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
CGAIOGLK_02255 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CGAIOGLK_02256 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CGAIOGLK_02257 1.3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
CGAIOGLK_02258 6.8e-251 lysP E amino acid
CGAIOGLK_02259 9.8e-180 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
CGAIOGLK_02260 6.3e-235 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
CGAIOGLK_02261 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CGAIOGLK_02262 4.9e-282 hutH 4.3.1.3 E Histidine ammonia-lyase
CGAIOGLK_02263 4.2e-77 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
CGAIOGLK_02264 6.7e-278 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
CGAIOGLK_02265 5.1e-20 S Domain of unknown function (DUF5082)
CGAIOGLK_02266 1.4e-38 yxiC S Family of unknown function (DUF5344)
CGAIOGLK_02267 2.1e-267 S nuclease activity
CGAIOGLK_02268 3.3e-47
CGAIOGLK_02269 5.5e-53
CGAIOGLK_02270 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CGAIOGLK_02271 5.5e-280 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CGAIOGLK_02272 1.1e-72 yxiE T Belongs to the universal stress protein A family
CGAIOGLK_02273 4.6e-121 1.14.11.45 E 2OG-Fe dioxygenase
CGAIOGLK_02274 1.2e-124 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CGAIOGLK_02275 2.4e-162 yxxF EG EamA-like transporter family
CGAIOGLK_02276 2.3e-35
CGAIOGLK_02277 9e-71 yxiG
CGAIOGLK_02278 1.2e-133
CGAIOGLK_02279 1.6e-86 yxiI S Protein of unknown function (DUF2716)
CGAIOGLK_02280 4.5e-43 yxiJ S YxiJ-like protein
CGAIOGLK_02283 1.9e-209 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
CGAIOGLK_02284 1.6e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
CGAIOGLK_02285 4.3e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
CGAIOGLK_02286 6.8e-111
CGAIOGLK_02287 3.1e-150 licT K transcriptional antiterminator
CGAIOGLK_02288 1.1e-143 exoK GH16 M licheninase activity
CGAIOGLK_02289 6.6e-224 citH C Citrate transporter
CGAIOGLK_02290 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
CGAIOGLK_02291 8.7e-47 yxiS
CGAIOGLK_02292 1.7e-98 T Domain of unknown function (DUF4163)
CGAIOGLK_02293 4.1e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CGAIOGLK_02294 5.5e-158 rlmA 2.1.1.187 Q Methyltransferase domain
CGAIOGLK_02295 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
CGAIOGLK_02296 2e-129 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CGAIOGLK_02297 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
CGAIOGLK_02298 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
CGAIOGLK_02299 2.8e-218 yxjG 2.1.1.14 E Methionine synthase
CGAIOGLK_02300 8.7e-220 yxjG 2.1.1.14 E Methionine synthase
CGAIOGLK_02301 7.1e-86 yxjI S LURP-one-related
CGAIOGLK_02304 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
CGAIOGLK_02305 4.9e-114 K helix_turn_helix, Lux Regulon
CGAIOGLK_02306 1.6e-187 yxjM T Signal transduction histidine kinase
CGAIOGLK_02307 7.7e-77 S Protein of unknown function (DUF1453)
CGAIOGLK_02308 6.7e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CGAIOGLK_02309 1.4e-73 yxkC S Domain of unknown function (DUF4352)
CGAIOGLK_02310 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
CGAIOGLK_02311 2.5e-272 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CGAIOGLK_02312 3.5e-163 lrp QT PucR C-terminal helix-turn-helix domain
CGAIOGLK_02313 5.9e-205 msmK P Belongs to the ABC transporter superfamily
CGAIOGLK_02314 4.3e-155 yxkH G Polysaccharide deacetylase
CGAIOGLK_02316 6.7e-309 3.4.24.84 O Peptidase family M48
CGAIOGLK_02317 1.5e-229 cimH C COG3493 Na citrate symporter
CGAIOGLK_02318 6.9e-267 cydA 1.10.3.14 C oxidase, subunit
CGAIOGLK_02319 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
CGAIOGLK_02320 0.0 cydD V ATP-binding
CGAIOGLK_02321 0.0 cydD V ATP-binding protein
CGAIOGLK_02322 1.6e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CGAIOGLK_02323 6.6e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
CGAIOGLK_02324 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
CGAIOGLK_02325 3.9e-48 yxlC S Family of unknown function (DUF5345)
CGAIOGLK_02326 1.4e-30
CGAIOGLK_02327 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
CGAIOGLK_02328 4.8e-165 yxlF V ABC transporter, ATP-binding protein
CGAIOGLK_02329 4e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
CGAIOGLK_02330 3.3e-209 yxlH EGP Major facilitator Superfamily
CGAIOGLK_02331 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
CGAIOGLK_02332 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
CGAIOGLK_02333 1.1e-19 yxzF
CGAIOGLK_02334 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
CGAIOGLK_02335 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
CGAIOGLK_02336 2.8e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CGAIOGLK_02337 5.6e-37 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
CGAIOGLK_02338 5.4e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
CGAIOGLK_02339 6.9e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
CGAIOGLK_02340 2.1e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
CGAIOGLK_02341 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CGAIOGLK_02342 9.6e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CGAIOGLK_02343 1.2e-232 dltB M membrane protein involved in D-alanine export
CGAIOGLK_02344 9.7e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CGAIOGLK_02345 5.1e-15 S D-Ala-teichoic acid biosynthesis protein
CGAIOGLK_02346 2.3e-165 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
CGAIOGLK_02347 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
CGAIOGLK_02348 4e-130 ynfM EGP Major facilitator Superfamily
CGAIOGLK_02349 4.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
CGAIOGLK_02350 1.4e-92 K Helix-turn-helix XRE-family like proteins
CGAIOGLK_02351 6.8e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
CGAIOGLK_02352 1.3e-232 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CGAIOGLK_02353 4e-87 ywaE K Transcriptional regulator
CGAIOGLK_02354 1.5e-124 ywaF S Integral membrane protein
CGAIOGLK_02355 9.4e-166 gspA M General stress
CGAIOGLK_02356 4e-153 sacY K transcriptional antiterminator
CGAIOGLK_02357 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CGAIOGLK_02358 2.9e-271 epr 3.4.21.62 O Belongs to the peptidase S8 family
CGAIOGLK_02359 7.8e-244 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CGAIOGLK_02360 9.9e-67 ywbC 4.4.1.5 E glyoxalase
CGAIOGLK_02361 2e-219 ywbD 2.1.1.191 J Methyltransferase
CGAIOGLK_02362 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
CGAIOGLK_02363 3.1e-207 ywbF EGP Major facilitator Superfamily
CGAIOGLK_02364 5.2e-111 ywbG M effector of murein hydrolase
CGAIOGLK_02365 1.1e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
CGAIOGLK_02366 2.1e-152 ywbI K Transcriptional regulator
CGAIOGLK_02367 1.4e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CGAIOGLK_02368 4.2e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
CGAIOGLK_02369 4.5e-253 P COG0672 High-affinity Fe2 Pb2 permease
CGAIOGLK_02370 1.3e-183 ycdO P periplasmic lipoprotein involved in iron transport
CGAIOGLK_02371 4.9e-224 ywbN P Dyp-type peroxidase family protein
CGAIOGLK_02372 7.6e-109 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
CGAIOGLK_02373 1.4e-265 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGAIOGLK_02374 9.8e-49 ywcB S Protein of unknown function, DUF485
CGAIOGLK_02376 1.1e-121 ywcC K transcriptional regulator
CGAIOGLK_02377 9.5e-60 gtcA S GtrA-like protein
CGAIOGLK_02378 2.6e-227 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CGAIOGLK_02379 6.2e-301 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
CGAIOGLK_02380 1e-35 ywzA S membrane
CGAIOGLK_02381 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
CGAIOGLK_02382 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CGAIOGLK_02383 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
CGAIOGLK_02384 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
CGAIOGLK_02385 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
CGAIOGLK_02386 8.6e-202 rodA D Belongs to the SEDS family
CGAIOGLK_02387 6.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
CGAIOGLK_02388 3.3e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGAIOGLK_02389 0.0 vpr O Belongs to the peptidase S8 family
CGAIOGLK_02391 9.1e-150 sacT K transcriptional antiterminator
CGAIOGLK_02392 5.7e-138 focA P Formate/nitrite transporter
CGAIOGLK_02393 1.6e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CGAIOGLK_02394 9.5e-288 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
CGAIOGLK_02395 7e-29 ywdA
CGAIOGLK_02396 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
CGAIOGLK_02397 1.3e-57 pex K Transcriptional regulator PadR-like family
CGAIOGLK_02398 1.4e-113 ywdD
CGAIOGLK_02400 1.2e-151 ywdF GT2,GT4 S Glycosyltransferase like family 2
CGAIOGLK_02401 1.1e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CGAIOGLK_02402 1.9e-261 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
CGAIOGLK_02403 6.6e-48 ywdI S Family of unknown function (DUF5327)
CGAIOGLK_02404 1.1e-237 ywdJ F Xanthine uracil
CGAIOGLK_02405 4.3e-59 ywdK S small membrane protein
CGAIOGLK_02406 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
CGAIOGLK_02407 6.9e-144 spsA M Spore Coat
CGAIOGLK_02408 4.7e-268 spsB M Capsule polysaccharide biosynthesis protein
CGAIOGLK_02409 5.1e-223 spsC E Belongs to the DegT DnrJ EryC1 family
CGAIOGLK_02410 1.7e-162 spsD 2.3.1.210 K Spore Coat
CGAIOGLK_02411 1.3e-212 spsE 2.5.1.56 M acid synthase
CGAIOGLK_02412 9.1e-130 spsF M Spore Coat
CGAIOGLK_02413 2.7e-188 spsG M Spore Coat
CGAIOGLK_02414 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CGAIOGLK_02415 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CGAIOGLK_02416 2.2e-159 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CGAIOGLK_02417 2.3e-86 spsL 5.1.3.13 M Spore Coat
CGAIOGLK_02418 1.2e-77
CGAIOGLK_02419 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
CGAIOGLK_02420 1.6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
CGAIOGLK_02421 0.0 rocB E arginine degradation protein
CGAIOGLK_02422 4.8e-249 lysP E amino acid
CGAIOGLK_02423 1.3e-205 ywfA EGP Major facilitator Superfamily
CGAIOGLK_02424 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
CGAIOGLK_02425 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
CGAIOGLK_02426 5.1e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CGAIOGLK_02427 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
CGAIOGLK_02428 8.6e-210 bacE EGP Major facilitator Superfamily
CGAIOGLK_02429 2.3e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
CGAIOGLK_02430 4e-139 IQ Enoyl-(Acyl carrier protein) reductase
CGAIOGLK_02431 1.1e-146 ywfI C May function as heme-dependent peroxidase
CGAIOGLK_02432 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
CGAIOGLK_02433 9.2e-164 cysL K Transcriptional regulator
CGAIOGLK_02434 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
CGAIOGLK_02435 2.2e-157 ywfM EG EamA-like transporter family
CGAIOGLK_02436 1e-110 rsfA_1
CGAIOGLK_02437 3.1e-36 ywzC S Belongs to the UPF0741 family
CGAIOGLK_02438 5.1e-256 ywfO S COG1078 HD superfamily phosphohydrolases
CGAIOGLK_02439 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
CGAIOGLK_02440 2.4e-78 yffB K Transcriptional regulator
CGAIOGLK_02441 8.8e-238 mmr U Major Facilitator Superfamily
CGAIOGLK_02443 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CGAIOGLK_02444 3.3e-71 ywhA K Transcriptional regulator
CGAIOGLK_02445 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
CGAIOGLK_02446 5.1e-119 ywhC S Peptidase family M50
CGAIOGLK_02447 2.6e-94 ywhD S YwhD family
CGAIOGLK_02448 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CGAIOGLK_02449 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CGAIOGLK_02450 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
CGAIOGLK_02452 7.5e-86 S aspartate phosphatase
CGAIOGLK_02453 2.8e-196 ywhK CO amine dehydrogenase activity
CGAIOGLK_02454 6.2e-244 ywhL CO amine dehydrogenase activity
CGAIOGLK_02456 1e-248 L Peptidase, M16
CGAIOGLK_02457 1.2e-214 2.7.1.26, 2.7.7.2 L Peptidase, M16
CGAIOGLK_02458 4.7e-233 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
CGAIOGLK_02459 4.8e-131 cbiO V ABC transporter
CGAIOGLK_02461 4.2e-269 C Fe-S oxidoreductases
CGAIOGLK_02462 1e-07 S Bacteriocin subtilosin A
CGAIOGLK_02463 1.8e-72 ywiB S protein conserved in bacteria
CGAIOGLK_02464 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
CGAIOGLK_02465 3e-213 narK P COG2223 Nitrate nitrite transporter
CGAIOGLK_02466 3.4e-129 fnr K helix_turn_helix, cAMP Regulatory protein
CGAIOGLK_02467 6.9e-138 ywiC S YwiC-like protein
CGAIOGLK_02468 7e-86 arfM T cyclic nucleotide binding
CGAIOGLK_02469 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CGAIOGLK_02470 5.7e-296 narH 1.7.5.1 C Nitrate reductase, beta
CGAIOGLK_02471 2.4e-93 narJ 1.7.5.1 C nitrate reductase
CGAIOGLK_02472 1.8e-124 narI 1.7.5.1 C nitrate reductase, gamma
CGAIOGLK_02473 1.9e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CGAIOGLK_02474 0.0 ywjA V ABC transporter
CGAIOGLK_02475 5.3e-95 ywjB H RibD C-terminal domain
CGAIOGLK_02476 2.7e-42 ywjC
CGAIOGLK_02477 3.3e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
CGAIOGLK_02478 5.8e-222 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
CGAIOGLK_02479 0.0 fadF C COG0247 Fe-S oxidoreductase
CGAIOGLK_02480 9.7e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
CGAIOGLK_02481 1.5e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CGAIOGLK_02482 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CGAIOGLK_02483 5.1e-90 ywjG S Domain of unknown function (DUF2529)
CGAIOGLK_02484 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
CGAIOGLK_02485 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
CGAIOGLK_02486 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CGAIOGLK_02487 3.3e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CGAIOGLK_02488 9.5e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
CGAIOGLK_02489 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CGAIOGLK_02490 1.1e-32 rpmE J Binds the 23S rRNA
CGAIOGLK_02491 7e-104 tdk 2.7.1.21 F thymidine kinase
CGAIOGLK_02492 0.0 sfcA 1.1.1.38 C malic enzyme
CGAIOGLK_02493 8.6e-160 ywkB S Membrane transport protein
CGAIOGLK_02494 1.6e-89 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
CGAIOGLK_02495 2e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CGAIOGLK_02496 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CGAIOGLK_02497 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CGAIOGLK_02499 4.8e-55 ywlA S Uncharacterised protein family (UPF0715)
CGAIOGLK_02500 6.1e-112 spoIIR S stage II sporulation protein R
CGAIOGLK_02501 4.7e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
CGAIOGLK_02502 8.1e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CGAIOGLK_02503 3.8e-91 mntP P Probably functions as a manganese efflux pump
CGAIOGLK_02504 8.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CGAIOGLK_02505 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
CGAIOGLK_02506 1.6e-94 ywlG S Belongs to the UPF0340 family
CGAIOGLK_02507 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CGAIOGLK_02508 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CGAIOGLK_02509 2.5e-62 atpI S ATP synthase
CGAIOGLK_02510 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
CGAIOGLK_02511 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CGAIOGLK_02512 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CGAIOGLK_02513 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CGAIOGLK_02514 3.4e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CGAIOGLK_02515 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CGAIOGLK_02516 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CGAIOGLK_02517 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
CGAIOGLK_02518 4.3e-88 ywmA
CGAIOGLK_02519 1.3e-32 ywzB S membrane
CGAIOGLK_02520 2e-132 ywmB S TATA-box binding
CGAIOGLK_02521 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CGAIOGLK_02522 9.2e-176 spoIID D Stage II sporulation protein D
CGAIOGLK_02523 5.1e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
CGAIOGLK_02524 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
CGAIOGLK_02526 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CGAIOGLK_02527 2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CGAIOGLK_02528 7.9e-104 S response regulator aspartate phosphatase
CGAIOGLK_02529 3e-84 ywmF S Peptidase M50
CGAIOGLK_02530 3.8e-11 csbD K CsbD-like
CGAIOGLK_02531 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
CGAIOGLK_02532 1.7e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
CGAIOGLK_02533 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
CGAIOGLK_02534 1.7e-64 ywnA K Transcriptional regulator
CGAIOGLK_02535 1.8e-113 ywnB S NAD(P)H-binding
CGAIOGLK_02536 8.4e-58 ywnC S Family of unknown function (DUF5362)
CGAIOGLK_02537 1.6e-143 mta K transcriptional
CGAIOGLK_02538 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CGAIOGLK_02539 2.2e-70 ywnF S Family of unknown function (DUF5392)
CGAIOGLK_02540 4.5e-14 ywnC S Family of unknown function (DUF5362)
CGAIOGLK_02541 6.4e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
CGAIOGLK_02542 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
CGAIOGLK_02543 3.5e-73 ywnJ S VanZ like family
CGAIOGLK_02544 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
CGAIOGLK_02545 1.6e-58 nrgB K Belongs to the P(II) protein family
CGAIOGLK_02546 7.4e-225 amt P Ammonium transporter
CGAIOGLK_02547 2.2e-76
CGAIOGLK_02548 1.5e-103 phzA Q Isochorismatase family
CGAIOGLK_02549 9.8e-242 ywoD EGP Major facilitator superfamily
CGAIOGLK_02550 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
CGAIOGLK_02551 1.2e-231 ywoF P Right handed beta helix region
CGAIOGLK_02552 7.8e-211 ywoG EGP Major facilitator Superfamily
CGAIOGLK_02553 2.1e-70 ywoH K COG1846 Transcriptional regulators
CGAIOGLK_02554 3e-44 spoIIID K Stage III sporulation protein D
CGAIOGLK_02555 3.5e-180 mbl D Rod shape-determining protein
CGAIOGLK_02556 1.7e-124 flhO N flagellar basal body
CGAIOGLK_02557 2.6e-141 flhP N flagellar basal body
CGAIOGLK_02558 7.5e-197 S aspartate phosphatase
CGAIOGLK_02559 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CGAIOGLK_02560 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CGAIOGLK_02561 4.9e-146 ywpD T Histidine kinase
CGAIOGLK_02562 2.7e-46 srtA 3.4.22.70 M Sortase family
CGAIOGLK_02563 1.1e-66 ywpF S YwpF-like protein
CGAIOGLK_02564 3.8e-66 ywpG
CGAIOGLK_02565 3.7e-57 ssbB L Single-stranded DNA-binding protein
CGAIOGLK_02566 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
CGAIOGLK_02567 1.8e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
CGAIOGLK_02568 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
CGAIOGLK_02569 4.6e-307 ywqB S SWIM zinc finger
CGAIOGLK_02570 1.2e-17
CGAIOGLK_02571 2e-116 ywqC M biosynthesis protein
CGAIOGLK_02572 8.4e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
CGAIOGLK_02573 3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
CGAIOGLK_02574 3e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CGAIOGLK_02575 1.7e-150 ywqG S Domain of unknown function (DUF1963)
CGAIOGLK_02576 1e-19 S Domain of unknown function (DUF5082)
CGAIOGLK_02577 2e-37 ywqI S Family of unknown function (DUF5344)
CGAIOGLK_02578 2.6e-213 ywqJ S Pre-toxin TG
CGAIOGLK_02579 7.9e-43
CGAIOGLK_02580 5.2e-17
CGAIOGLK_02581 5.2e-79 ywqJ S Pre-toxin TG
CGAIOGLK_02582 1.4e-75
CGAIOGLK_02583 7.4e-51
CGAIOGLK_02585 2e-99
CGAIOGLK_02586 2.6e-121 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
CGAIOGLK_02587 1.4e-161 K Transcriptional regulator
CGAIOGLK_02588 1.1e-100 ywqN S NAD(P)H-dependent
CGAIOGLK_02590 9.9e-89 ywrA P COG2059 Chromate transport protein ChrA
CGAIOGLK_02591 1.2e-103 ywrB P Chromate transporter
CGAIOGLK_02592 8e-82 ywrC K Transcriptional regulator
CGAIOGLK_02593 9.7e-302 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
CGAIOGLK_02594 5e-54 S Domain of unknown function (DUF4181)
CGAIOGLK_02595 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CGAIOGLK_02596 3.7e-12
CGAIOGLK_02597 6e-210 cotH M Spore Coat
CGAIOGLK_02598 7.6e-131 cotB
CGAIOGLK_02599 4.5e-123 ywrJ
CGAIOGLK_02600 3.6e-219 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CGAIOGLK_02601 1.1e-169 alsR K LysR substrate binding domain
CGAIOGLK_02602 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
CGAIOGLK_02603 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
CGAIOGLK_02604 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
CGAIOGLK_02605 8e-48 ywsA S Protein of unknown function (DUF3892)
CGAIOGLK_02606 3.3e-92 batE T Sh3 type 3 domain protein
CGAIOGLK_02607 2.4e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
CGAIOGLK_02608 9.3e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
CGAIOGLK_02609 2.1e-274 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
CGAIOGLK_02610 9e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
CGAIOGLK_02611 6.5e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGAIOGLK_02612 5.5e-178 rbsR K transcriptional
CGAIOGLK_02613 8e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
CGAIOGLK_02614 8.6e-70 pgsC S biosynthesis protein
CGAIOGLK_02615 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
CGAIOGLK_02616 3.6e-21 ywtC
CGAIOGLK_02617 2.4e-239 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
CGAIOGLK_02618 3.5e-160 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
CGAIOGLK_02619 1.1e-170 ywtF K Transcriptional regulator
CGAIOGLK_02620 3.5e-247 ywtG EGP Major facilitator Superfamily
CGAIOGLK_02621 1.5e-211 gerAC S Spore germination protein
CGAIOGLK_02622 5.4e-198 gerBB E Spore germination protein
CGAIOGLK_02623 1e-265 gerBA EG Spore germination protein
CGAIOGLK_02624 7.1e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
CGAIOGLK_02625 3.6e-216 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CGAIOGLK_02626 1.7e-259
CGAIOGLK_02627 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CGAIOGLK_02628 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
CGAIOGLK_02629 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
CGAIOGLK_02630 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
CGAIOGLK_02631 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CGAIOGLK_02632 1.1e-150 tagG GM Transport permease protein
CGAIOGLK_02633 1.8e-279 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
CGAIOGLK_02634 1.5e-109 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
CGAIOGLK_02635 6.6e-39 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CGAIOGLK_02636 7.5e-93 ggaA M Glycosyltransferase like family 2
CGAIOGLK_02637 4.8e-208 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
CGAIOGLK_02638 6.5e-57
CGAIOGLK_02639 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
CGAIOGLK_02640 1e-215 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CGAIOGLK_02641 4e-162 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
CGAIOGLK_02642 6e-38
CGAIOGLK_02643 0.0 lytB 3.5.1.28 D Stage II sporulation protein
CGAIOGLK_02644 4.8e-266 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
CGAIOGLK_02645 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
CGAIOGLK_02646 1.3e-247 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CGAIOGLK_02647 3.2e-217 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
CGAIOGLK_02648 2.6e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CGAIOGLK_02649 6.3e-263 tuaE M Teichuronic acid biosynthesis protein
CGAIOGLK_02650 9.5e-113 tuaF M protein involved in exopolysaccharide biosynthesis
CGAIOGLK_02651 1.1e-144 tuaG GT2 M Glycosyltransferase like family 2
CGAIOGLK_02652 2.1e-235 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
CGAIOGLK_02653 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
CGAIOGLK_02654 1.7e-162 yvhJ K Transcriptional regulator
CGAIOGLK_02655 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
CGAIOGLK_02656 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
CGAIOGLK_02657 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CGAIOGLK_02658 7.3e-155 degV S protein conserved in bacteria
CGAIOGLK_02659 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CGAIOGLK_02660 3.7e-45 comFB S Late competence development protein ComFB
CGAIOGLK_02661 6.8e-125 comFC S Phosphoribosyl transferase domain
CGAIOGLK_02662 7e-74 yvyF S flagellar protein
CGAIOGLK_02663 1.6e-39 flgM KNU Negative regulator of flagellin synthesis
CGAIOGLK_02664 7.1e-78 flgN NOU FlgN protein
CGAIOGLK_02665 2e-264 flgK N flagellar hook-associated protein
CGAIOGLK_02666 7.8e-155 flgL N Belongs to the bacterial flagellin family
CGAIOGLK_02667 5.7e-50 yviE
CGAIOGLK_02668 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CGAIOGLK_02669 6.3e-29 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CGAIOGLK_02670 5.9e-93 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CGAIOGLK_02671 7.8e-52 flaG N flagellar protein FlaG
CGAIOGLK_02672 2.2e-247 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CGAIOGLK_02673 2.9e-69 fliS N flagellar protein FliS
CGAIOGLK_02674 1.9e-08 fliT S bacterial-type flagellum organization
CGAIOGLK_02675 2.8e-66
CGAIOGLK_02676 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CGAIOGLK_02677 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CGAIOGLK_02678 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CGAIOGLK_02679 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
CGAIOGLK_02680 3e-51 cccB C COG2010 Cytochrome c, mono- and diheme variants
CGAIOGLK_02681 4.1e-54 V ABC-2 type transporter
CGAIOGLK_02682 5.2e-83 V ABC transporter
CGAIOGLK_02683 1.7e-52 MA20_23385 V ABC-2 type transporter
CGAIOGLK_02684 1.1e-22 S CAAX protease self-immunity
CGAIOGLK_02686 8e-55
CGAIOGLK_02687 4.4e-48 2.7.6.3, 2.7.7.18 H HD domain
CGAIOGLK_02688 6.3e-32 3.1.3.102, 3.1.3.104, 3.1.3.5 S haloacid dehalogenase-like hydrolase
CGAIOGLK_02689 1.9e-17 L Belongs to the Nudix hydrolase family
CGAIOGLK_02691 2.7e-12 2.7.8.12 M Glycosyl transferase family 2
CGAIOGLK_02692 7.9e-49 3.5.3.6 E Amidinotransferase
CGAIOGLK_02694 2.7e-123 ftsE D cell division ATP-binding protein FtsE
CGAIOGLK_02695 1.3e-154 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
CGAIOGLK_02696 9.9e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
CGAIOGLK_02697 5.3e-56 swrA S Swarming motility protein
CGAIOGLK_02698 2e-219 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CGAIOGLK_02699 4.8e-225 yvkA EGP Major facilitator Superfamily
CGAIOGLK_02700 7e-101 yvkB K Transcriptional regulator
CGAIOGLK_02701 0.0 yvkC 2.7.9.2 GT Phosphotransferase
CGAIOGLK_02702 1.2e-30 csbA S protein conserved in bacteria
CGAIOGLK_02703 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CGAIOGLK_02704 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CGAIOGLK_02705 1.2e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CGAIOGLK_02706 6.7e-34 yvkN
CGAIOGLK_02707 8e-49 yvlA
CGAIOGLK_02708 7.5e-168 yvlB S Putative adhesin
CGAIOGLK_02709 2.6e-26 pspB KT PspC domain
CGAIOGLK_02710 1.2e-50 yvlD S Membrane
CGAIOGLK_02711 2.7e-203 yvmA EGP Major facilitator Superfamily
CGAIOGLK_02712 2e-86 yvmB K helix_turn_helix multiple antibiotic resistance protein
CGAIOGLK_02713 4.4e-135 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
CGAIOGLK_02714 1.2e-227 cypX 1.14.15.13 C Cytochrome P450
CGAIOGLK_02715 3.3e-80 adcR K helix_turn_helix multiple antibiotic resistance protein
CGAIOGLK_02716 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
CGAIOGLK_02717 3.6e-134 yvoA K transcriptional
CGAIOGLK_02718 2e-129 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CGAIOGLK_02719 2.4e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
CGAIOGLK_02720 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CGAIOGLK_02721 3.2e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CGAIOGLK_02722 1.5e-161 yvoD P COG0370 Fe2 transport system protein B
CGAIOGLK_02723 6.1e-117 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
CGAIOGLK_02724 2.1e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
CGAIOGLK_02725 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
CGAIOGLK_02726 1.9e-138 yvpB NU protein conserved in bacteria
CGAIOGLK_02727 4.5e-219 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CGAIOGLK_02728 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
CGAIOGLK_02729 4.4e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CGAIOGLK_02730 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
CGAIOGLK_02731 6.2e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CGAIOGLK_02732 1.1e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CGAIOGLK_02733 8.1e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
CGAIOGLK_02734 3.4e-109 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
CGAIOGLK_02735 1.7e-94 Otg1 S Predicted membrane protein (DUF2339)
CGAIOGLK_02736 3.1e-58
CGAIOGLK_02737 3.8e-75
CGAIOGLK_02738 0.0
CGAIOGLK_02740 0.0 msbA2 3.6.3.44 V ABC transporter
CGAIOGLK_02741 2.9e-276 S COG0457 FOG TPR repeat
CGAIOGLK_02742 1.1e-97 usp CBM50 M protein conserved in bacteria
CGAIOGLK_02743 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CGAIOGLK_02744 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
CGAIOGLK_02745 2.2e-165 rapZ S Displays ATPase and GTPase activities
CGAIOGLK_02746 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
CGAIOGLK_02747 1.4e-170 whiA K May be required for sporulation
CGAIOGLK_02748 8e-36 crh G Phosphocarrier protein Chr
CGAIOGLK_02749 2.9e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
CGAIOGLK_02750 8.8e-33
CGAIOGLK_02751 1.9e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CGAIOGLK_02752 3.1e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
CGAIOGLK_02753 5.6e-141 yvcR V ABC transporter, ATP-binding protein
CGAIOGLK_02754 0.0 yxdM V ABC transporter (permease)
CGAIOGLK_02755 5.1e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CGAIOGLK_02756 6.3e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
CGAIOGLK_02757 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
CGAIOGLK_02758 2e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
CGAIOGLK_02759 1.6e-105 yvdD 3.2.2.10 S Belongs to the LOG family
CGAIOGLK_02760 1.4e-173 yvdE K Transcriptional regulator
CGAIOGLK_02761 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
CGAIOGLK_02764 6.1e-157 ydhU P Catalase
CGAIOGLK_02765 1.5e-213 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
CGAIOGLK_02766 1.1e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
CGAIOGLK_02767 6.6e-170 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
CGAIOGLK_02768 1.1e-132 ydhQ K UTRA
CGAIOGLK_02769 5.2e-283 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CGAIOGLK_02770 2.6e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CGAIOGLK_02771 1.3e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
CGAIOGLK_02772 1.1e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
CGAIOGLK_02773 4.6e-200 pbuE EGP Major facilitator Superfamily
CGAIOGLK_02774 9.5e-98 ydhK M Protein of unknown function (DUF1541)
CGAIOGLK_02775 2.8e-182 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
CGAIOGLK_02776 8.8e-81 K Acetyltransferase (GNAT) domain
CGAIOGLK_02778 8.7e-68 frataxin S Domain of unknown function (DU1801)
CGAIOGLK_02779 5.2e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
CGAIOGLK_02780 1.6e-123
CGAIOGLK_02781 1.7e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
CGAIOGLK_02782 4.8e-243 ydhD M Glycosyl hydrolase
CGAIOGLK_02783 6.5e-122 ydhC K FCD
CGAIOGLK_02784 1.2e-121 ydhB S membrane transporter protein
CGAIOGLK_02785 2.5e-209 tcaB EGP Major facilitator Superfamily
CGAIOGLK_02786 2.4e-69 ydgJ K Winged helix DNA-binding domain
CGAIOGLK_02787 1e-113 drgA C nitroreductase
CGAIOGLK_02788 0.0 ydgH S drug exporters of the RND superfamily
CGAIOGLK_02789 8.9e-79 K helix_turn_helix multiple antibiotic resistance protein
CGAIOGLK_02790 6e-91 dinB S DinB family
CGAIOGLK_02791 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
CGAIOGLK_02792 1.8e-303 expZ S ABC transporter
CGAIOGLK_02793 9e-86 yycN 2.3.1.128 K Acetyltransferase
CGAIOGLK_02794 4.8e-52 S DoxX-like family
CGAIOGLK_02795 3.1e-99 K Bacterial regulatory proteins, tetR family
CGAIOGLK_02796 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
CGAIOGLK_02797 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
CGAIOGLK_02798 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
CGAIOGLK_02799 5.2e-122 ydfS S Protein of unknown function (DUF421)
CGAIOGLK_02800 4.4e-118 ydfR S Protein of unknown function (DUF421)
CGAIOGLK_02802 6.3e-29
CGAIOGLK_02803 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
CGAIOGLK_02804 7.7e-55 traF CO Thioredoxin
CGAIOGLK_02805 8.8e-63 mhqP S DoxX
CGAIOGLK_02806 4e-186 ydfO E COG0346 Lactoylglutathione lyase and related lyases
CGAIOGLK_02807 1.1e-110 ydfN C nitroreductase
CGAIOGLK_02808 1.7e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CGAIOGLK_02809 3e-145 K Bacterial transcription activator, effector binding domain
CGAIOGLK_02810 1e-114 S Protein of unknown function (DUF554)
CGAIOGLK_02811 1.1e-172 S Alpha/beta hydrolase family
CGAIOGLK_02812 0.0 ydfJ S drug exporters of the RND superfamily
CGAIOGLK_02813 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CGAIOGLK_02814 2.2e-178 ydfH 2.7.13.3 T Histidine kinase
CGAIOGLK_02816 1e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CGAIOGLK_02817 1.7e-122 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
CGAIOGLK_02818 5e-116 ydfE S Flavin reductase like domain
CGAIOGLK_02819 1e-273 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CGAIOGLK_02820 8.8e-162 ydfC EG EamA-like transporter family
CGAIOGLK_02821 2.1e-148 ydfB J GNAT acetyltransferase
CGAIOGLK_02822 3.3e-231 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CGAIOGLK_02823 2.8e-57 arsR K transcriptional
CGAIOGLK_02824 2.1e-103 ydeS K Transcriptional regulator
CGAIOGLK_02825 9.5e-193 ydeR EGP Major facilitator Superfamily
CGAIOGLK_02826 4.2e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
CGAIOGLK_02827 8.9e-56 K HxlR-like helix-turn-helix
CGAIOGLK_02828 3.1e-104 ydeN S Serine hydrolase
CGAIOGLK_02829 4.2e-74 maoC I N-terminal half of MaoC dehydratase
CGAIOGLK_02830 1.2e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CGAIOGLK_02831 9.2e-153 ydeK EG -transporter
CGAIOGLK_02832 8.8e-85 K Transcriptional regulator C-terminal region
CGAIOGLK_02833 8.3e-15 ptsH G PTS HPr component phosphorylation site
CGAIOGLK_02834 1.1e-31 S SNARE associated Golgi protein
CGAIOGLK_02835 7.8e-112
CGAIOGLK_02836 6.4e-105 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
CGAIOGLK_02837 2.7e-45 ydeH
CGAIOGLK_02838 3.1e-25 ydeG EGP Major facilitator superfamily
CGAIOGLK_02839 5.5e-176 ydeG EGP Major facilitator superfamily
CGAIOGLK_02840 1.8e-259 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CGAIOGLK_02841 6.9e-164 ydeE K AraC family transcriptional regulator
CGAIOGLK_02842 3.2e-170 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
CGAIOGLK_02843 1.9e-161 rhaS5 K AraC-like ligand binding domain
CGAIOGLK_02844 2.6e-142 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
CGAIOGLK_02845 2.3e-78 carD K Transcription factor
CGAIOGLK_02846 8.7e-30 cspL K Cold shock
CGAIOGLK_02847 5.4e-192 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
CGAIOGLK_02848 4.6e-42
CGAIOGLK_02849 1.7e-32 K Helix-turn-helix XRE-family like proteins
CGAIOGLK_02850 2.4e-135 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
CGAIOGLK_02851 2.8e-25 S LXG domain of WXG superfamily
CGAIOGLK_02852 9.4e-44
CGAIOGLK_02853 1.5e-74 rimJ2 J Acetyltransferase (GNAT) domain
CGAIOGLK_02861 8.1e-84 ydcK S Belongs to the SprT family
CGAIOGLK_02862 0.0 yhgF K COG2183 Transcriptional accessory protein
CGAIOGLK_02863 1.1e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
CGAIOGLK_02864 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CGAIOGLK_02865 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
CGAIOGLK_02866 2e-52 rsbV T Belongs to the anti-sigma-factor antagonist family
CGAIOGLK_02867 7.1e-189 rsbU 3.1.3.3 KT phosphatase
CGAIOGLK_02868 2.9e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
CGAIOGLK_02869 5.2e-57 rsbS T antagonist
CGAIOGLK_02870 3.7e-143 rsbR T Positive regulator of sigma-B
CGAIOGLK_02871 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
CGAIOGLK_02872 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
CGAIOGLK_02873 3.3e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CGAIOGLK_02874 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
CGAIOGLK_02875 8e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CGAIOGLK_02876 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
CGAIOGLK_02877 2.5e-259 ydbT S Membrane
CGAIOGLK_02878 2.1e-82 ydbS S Bacterial PH domain
CGAIOGLK_02879 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CGAIOGLK_02880 2.1e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CGAIOGLK_02881 8.7e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
CGAIOGLK_02882 1.5e-55 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
CGAIOGLK_02883 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CGAIOGLK_02884 2.2e-07 S Fur-regulated basic protein A
CGAIOGLK_02885 1.1e-18 S Fur-regulated basic protein B
CGAIOGLK_02886 3e-220 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
CGAIOGLK_02887 2.7e-52 ydbL
CGAIOGLK_02888 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
CGAIOGLK_02889 8.9e-170 ydbJ V ABC transporter, ATP-binding protein
CGAIOGLK_02891 4.4e-181 ydbI S AI-2E family transporter
CGAIOGLK_02892 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CGAIOGLK_02893 1.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
CGAIOGLK_02894 1.8e-295 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
CGAIOGLK_02895 2.3e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
CGAIOGLK_02896 3.5e-154 ydbD P Catalase
CGAIOGLK_02897 1.4e-62 ydbC S Domain of unknown function (DUF4937
CGAIOGLK_02898 8.9e-59 ydbB G Cupin domain
CGAIOGLK_02900 2.7e-146 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
CGAIOGLK_02901 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
CGAIOGLK_02903 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
CGAIOGLK_02904 9.4e-40
CGAIOGLK_02906 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
CGAIOGLK_02907 1.2e-76 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
CGAIOGLK_02908 0.0 ydaO E amino acid
CGAIOGLK_02909 0.0 ydaN S Bacterial cellulose synthase subunit
CGAIOGLK_02910 1.7e-232 ydaM M Glycosyl transferase family group 2
CGAIOGLK_02911 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
CGAIOGLK_02912 1.2e-149 ydaK T Diguanylate cyclase, GGDEF domain
CGAIOGLK_02913 2.1e-207 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
CGAIOGLK_02914 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CGAIOGLK_02915 2.5e-74 lrpC K Transcriptional regulator
CGAIOGLK_02916 3.3e-46 ydzA EGP Major facilitator Superfamily
CGAIOGLK_02917 2.3e-137 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
CGAIOGLK_02918 6.8e-77 ydaG 1.4.3.5 S general stress protein
CGAIOGLK_02919 1.9e-103 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CGAIOGLK_02920 7.8e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
CGAIOGLK_02921 3.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CGAIOGLK_02922 9e-99 ydaC Q Methyltransferase domain
CGAIOGLK_02923 2.1e-293 ydaB IQ acyl-CoA ligase
CGAIOGLK_02924 0.0 mtlR K transcriptional regulator, MtlR
CGAIOGLK_02925 8.3e-173 ydhF S Oxidoreductase
CGAIOGLK_02926 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
CGAIOGLK_02927 8e-47 yczJ S biosynthesis
CGAIOGLK_02929 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
CGAIOGLK_02930 1.2e-132 kipR K Transcriptional regulator
CGAIOGLK_02931 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
CGAIOGLK_02932 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
CGAIOGLK_02933 3.7e-148 ycsI S Belongs to the D-glutamate cyclase family
CGAIOGLK_02934 1.6e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
CGAIOGLK_02935 1.8e-139 ycsF S Belongs to the UPF0271 (lamB) family
CGAIOGLK_02936 2.3e-136 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
CGAIOGLK_02938 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
CGAIOGLK_02939 6.8e-110 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
CGAIOGLK_02940 4.2e-98 sipT 3.4.21.89 U Belongs to the peptidase S26 family
CGAIOGLK_02941 1.9e-200 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
CGAIOGLK_02942 1.8e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
CGAIOGLK_02943 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
CGAIOGLK_02944 7.4e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
CGAIOGLK_02945 3.4e-53
CGAIOGLK_02946 2.8e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
CGAIOGLK_02947 6.1e-307 ycnJ P protein, homolog of Cu resistance protein CopC
CGAIOGLK_02948 3.5e-98 ycnI S protein conserved in bacteria
CGAIOGLK_02949 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CGAIOGLK_02950 6.1e-149 glcU U Glucose uptake
CGAIOGLK_02951 1.7e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CGAIOGLK_02952 9.1e-245 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CGAIOGLK_02953 6.6e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CGAIOGLK_02954 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
CGAIOGLK_02955 1.6e-45 ycnE S Monooxygenase
CGAIOGLK_02956 2.2e-134 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
CGAIOGLK_02957 5.5e-153 ycnC K Transcriptional regulator
CGAIOGLK_02958 3.2e-251 ycnB EGP Major facilitator Superfamily
CGAIOGLK_02959 2.7e-174 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
CGAIOGLK_02960 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
CGAIOGLK_02961 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGAIOGLK_02962 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGAIOGLK_02963 2.8e-241 lysC 2.7.2.4 E Belongs to the aspartokinase family
CGAIOGLK_02967 5.8e-78 S aspartate phosphatase
CGAIOGLK_02968 6.3e-260 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
CGAIOGLK_02969 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CGAIOGLK_02970 2.8e-202 yclI V ABC transporter (permease) YclI
CGAIOGLK_02971 1.8e-119 yclH P ABC transporter
CGAIOGLK_02972 2.8e-194 gerKB F Spore germination protein
CGAIOGLK_02973 5.2e-226 gerKC S spore germination
CGAIOGLK_02974 1.5e-281 gerKA EG Spore germination protein
CGAIOGLK_02976 2.7e-308 yclG M Pectate lyase superfamily protein
CGAIOGLK_02977 4.7e-266 dtpT E amino acid peptide transporter
CGAIOGLK_02978 1.4e-158 yclE 3.4.11.5 S Alpha beta hydrolase
CGAIOGLK_02979 1.5e-80 yclD
CGAIOGLK_02980 4e-39 bsdD 4.1.1.61 S response to toxic substance
CGAIOGLK_02981 4.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
CGAIOGLK_02982 7.6e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
CGAIOGLK_02983 1.2e-160 bsdA K LysR substrate binding domain
CGAIOGLK_02984 6.4e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
CGAIOGLK_02985 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
CGAIOGLK_02986 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
CGAIOGLK_02987 9.7e-115 yczE S membrane
CGAIOGLK_02988 3.3e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
CGAIOGLK_02989 1.5e-250 ycxD K GntR family transcriptional regulator
CGAIOGLK_02990 1.2e-161 ycxC EG EamA-like transporter family
CGAIOGLK_02991 2.8e-86 S YcxB-like protein
CGAIOGLK_02992 1.2e-225 EGP Major Facilitator Superfamily
CGAIOGLK_02993 4.9e-139 srfAD Q thioesterase
CGAIOGLK_02994 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
CGAIOGLK_02995 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CGAIOGLK_02996 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CGAIOGLK_02997 1.3e-63 hxlR K transcriptional
CGAIOGLK_02998 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
CGAIOGLK_02999 3.9e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
CGAIOGLK_03000 1.3e-179 tlpC 2.7.13.3 NT chemotaxis protein
CGAIOGLK_03001 1e-70 nucA M Deoxyribonuclease NucA/NucB
CGAIOGLK_03002 6.5e-69 nin S Competence protein J (ComJ)
CGAIOGLK_03003 5.2e-294 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CGAIOGLK_03004 3.5e-121 S AAA domain
CGAIOGLK_03005 2.1e-23
CGAIOGLK_03006 1e-35 K MarR family
CGAIOGLK_03007 3.5e-52 yckD S Protein of unknown function (DUF2680)
CGAIOGLK_03008 1.9e-69 yckC S membrane
CGAIOGLK_03010 1.5e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
CGAIOGLK_03011 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
CGAIOGLK_03012 2e-227 yciC S GTPases (G3E family)
CGAIOGLK_03013 2.7e-108 yciB M ErfK YbiS YcfS YnhG
CGAIOGLK_03014 5.7e-169 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
CGAIOGLK_03015 1.7e-221 nasA P COG2223 Nitrate nitrite transporter
CGAIOGLK_03016 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
CGAIOGLK_03017 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CGAIOGLK_03018 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CGAIOGLK_03019 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
CGAIOGLK_03020 1.1e-275 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
CGAIOGLK_03021 2.4e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
CGAIOGLK_03022 4.5e-160 I alpha/beta hydrolase fold
CGAIOGLK_03023 1.2e-139 ycgR S permeases
CGAIOGLK_03024 6.3e-146 ycgQ S membrane
CGAIOGLK_03025 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
CGAIOGLK_03026 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGAIOGLK_03027 2.1e-293 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
CGAIOGLK_03028 5.1e-170 ycgM E Proline dehydrogenase
CGAIOGLK_03029 5.4e-144 ycgL S Predicted nucleotidyltransferase
CGAIOGLK_03030 2.3e-181 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
CGAIOGLK_03031 2.1e-174 oxyR3 K LysR substrate binding domain
CGAIOGLK_03032 5.8e-143 yafE Q ubiE/COQ5 methyltransferase family
CGAIOGLK_03033 1.9e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CGAIOGLK_03034 6.2e-108 tmrB S AAA domain
CGAIOGLK_03035 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CGAIOGLK_03036 2.4e-112 ycgI S Domain of unknown function (DUF1989)
CGAIOGLK_03037 4.8e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
CGAIOGLK_03038 2.6e-151 yqcI S YqcI/YcgG family
CGAIOGLK_03039 2.6e-112 ycgF E Lysine exporter protein LysE YggA
CGAIOGLK_03040 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
CGAIOGLK_03041 2.1e-261 mdr EGP Major facilitator Superfamily
CGAIOGLK_03042 5.2e-290 lctP C L-lactate permease
CGAIOGLK_03043 4.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
CGAIOGLK_03044 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
CGAIOGLK_03045 4.1e-81 ycgB
CGAIOGLK_03046 8.7e-257 ycgA S Membrane
CGAIOGLK_03047 1.3e-215 amhX S amidohydrolase
CGAIOGLK_03048 3.4e-163 opuAC E glycine betaine
CGAIOGLK_03049 1.3e-127 opuAB P glycine betaine
CGAIOGLK_03050 1.9e-228 proV 3.6.3.32 E glycine betaine
CGAIOGLK_03051 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
CGAIOGLK_03052 5.5e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
CGAIOGLK_03053 6.6e-218 naiP P Uncharacterised MFS-type transporter YbfB
CGAIOGLK_03054 2e-192 yceH P Belongs to the TelA family
CGAIOGLK_03055 0.0 yceG S Putative component of 'biosynthetic module'
CGAIOGLK_03056 1.4e-136 terC P Protein of unknown function (DUF475)
CGAIOGLK_03057 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
CGAIOGLK_03058 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
CGAIOGLK_03059 2.5e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
CGAIOGLK_03060 4.4e-183 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGAIOGLK_03061 6.4e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
CGAIOGLK_03062 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
CGAIOGLK_03063 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
CGAIOGLK_03064 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
CGAIOGLK_03065 1.2e-138 IQ Enoyl-(Acyl carrier protein) reductase
CGAIOGLK_03066 1.2e-173 S response regulator aspartate phosphatase
CGAIOGLK_03067 6.2e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
CGAIOGLK_03068 3.3e-259 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
CGAIOGLK_03069 1.8e-270 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
CGAIOGLK_03070 1.6e-170 ycdA S Domain of unknown function (DUF5105)
CGAIOGLK_03071 4.6e-174 yccK C Aldo keto reductase
CGAIOGLK_03072 5.5e-201 natB CP ABC-2 family transporter protein
CGAIOGLK_03073 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
CGAIOGLK_03074 1.2e-126 lytR_2 T LytTr DNA-binding domain
CGAIOGLK_03075 1.5e-159 2.7.13.3 T GHKL domain
CGAIOGLK_03076 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
CGAIOGLK_03077 7.1e-57 S RDD family
CGAIOGLK_03078 4.7e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
CGAIOGLK_03079 3.4e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
CGAIOGLK_03080 6.3e-102 yxaF K Transcriptional regulator
CGAIOGLK_03081 4.3e-224 lmrB EGP the major facilitator superfamily
CGAIOGLK_03082 1.2e-202 ycbU E Selenocysteine lyase
CGAIOGLK_03083 2.5e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CGAIOGLK_03084 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CGAIOGLK_03085 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
CGAIOGLK_03086 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
CGAIOGLK_03087 8.1e-134 ycbR T vWA found in TerF C terminus
CGAIOGLK_03088 1.1e-77 sleB 3.5.1.28 M Cell wall
CGAIOGLK_03089 4.1e-52 ycbP S Protein of unknown function (DUF2512)
CGAIOGLK_03090 5.1e-114 S ABC-2 family transporter protein
CGAIOGLK_03091 1.3e-165 ycbN V ABC transporter, ATP-binding protein
CGAIOGLK_03092 1.4e-167 T PhoQ Sensor
CGAIOGLK_03093 6.5e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CGAIOGLK_03094 2.4e-170 eamA1 EG spore germination
CGAIOGLK_03095 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
CGAIOGLK_03096 1.4e-175 ycbJ S Macrolide 2'-phosphotransferase
CGAIOGLK_03097 7.7e-296 garD 4.2.1.42, 4.2.1.7 G Altronate
CGAIOGLK_03098 2.1e-123 ycbG K FCD
CGAIOGLK_03099 5.5e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
CGAIOGLK_03100 1.3e-254 gudP G COG0477 Permeases of the major facilitator superfamily
CGAIOGLK_03101 1.1e-270 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CGAIOGLK_03102 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
CGAIOGLK_03103 9e-170 glnL T Regulator
CGAIOGLK_03104 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
CGAIOGLK_03105 3.8e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
CGAIOGLK_03106 2.8e-255 agcS E Sodium alanine symporter
CGAIOGLK_03108 7.4e-180 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
CGAIOGLK_03109 2.4e-251 mmuP E amino acid
CGAIOGLK_03110 4.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
CGAIOGLK_03112 3.1e-128 K UTRA
CGAIOGLK_03113 4.8e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CGAIOGLK_03114 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CGAIOGLK_03115 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CGAIOGLK_03116 1.2e-190 yceA S Belongs to the UPF0176 family
CGAIOGLK_03117 6.7e-167 ybfP K Transcriptional regulator
CGAIOGLK_03118 9.6e-250 S Erythromycin esterase
CGAIOGLK_03119 2.3e-44 ybfN
CGAIOGLK_03120 1.3e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
CGAIOGLK_03121 2.7e-85 ybfM S SNARE associated Golgi protein
CGAIOGLK_03122 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CGAIOGLK_03123 2.5e-169 S Alpha/beta hydrolase family
CGAIOGLK_03125 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
CGAIOGLK_03126 1.9e-214 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CGAIOGLK_03127 5.2e-145 msmR K AraC-like ligand binding domain
CGAIOGLK_03128 1.2e-161 ybfH EG EamA-like transporter family
CGAIOGLK_03129 0.0 ybfG M Domain of unknown function (DUF1906)
CGAIOGLK_03131 2.8e-219 ybfB G COG0477 Permeases of the major facilitator superfamily
CGAIOGLK_03132 1.5e-169 ybfA 3.4.15.5 K FR47-like protein
CGAIOGLK_03133 8.5e-35 S Protein of unknown function (DUF2651)
CGAIOGLK_03134 7.3e-258 glpT G -transporter
CGAIOGLK_03135 5.3e-164 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
CGAIOGLK_03136 1.8e-290 ybeC E amino acid
CGAIOGLK_03137 4.9e-41 ybyB
CGAIOGLK_03138 7.8e-246 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
CGAIOGLK_03139 5.2e-150 ybxI 3.5.2.6 V beta-lactamase
CGAIOGLK_03140 4.9e-30 ybxH S Family of unknown function (DUF5370)
CGAIOGLK_03141 1.1e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
CGAIOGLK_03142 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
CGAIOGLK_03143 3.6e-216 ybdO S Domain of unknown function (DUF4885)
CGAIOGLK_03144 7.7e-152 ybdN
CGAIOGLK_03146 6.8e-213 S Protein of unknown function (DUF1430)
CGAIOGLK_03147 3.1e-78 V ATPases associated with a variety of cellular activities
CGAIOGLK_03149 5.9e-47 V Beta-lactamase
CGAIOGLK_03150 5.8e-58
CGAIOGLK_03151 3.8e-202 ybcL EGP Major facilitator Superfamily
CGAIOGLK_03152 5.1e-50 ybzH K Helix-turn-helix domain
CGAIOGLK_03153 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
CGAIOGLK_03154 6.2e-45
CGAIOGLK_03155 1.1e-92 can 4.2.1.1 P carbonic anhydrase
CGAIOGLK_03156 0.0 ybcC S Belongs to the UPF0753 family
CGAIOGLK_03157 2e-275 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
CGAIOGLK_03158 2.1e-99 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CGAIOGLK_03159 1.3e-119 adaA 3.2.2.21 K Transcriptional regulator
CGAIOGLK_03160 1.1e-172 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CGAIOGLK_03161 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CGAIOGLK_03162 2.1e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CGAIOGLK_03163 1.5e-224 ybbR S protein conserved in bacteria
CGAIOGLK_03164 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CGAIOGLK_03165 2.7e-101 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
CGAIOGLK_03166 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
CGAIOGLK_03172 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
CGAIOGLK_03173 1.9e-86 ybbJ J acetyltransferase
CGAIOGLK_03174 3e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CGAIOGLK_03175 1.4e-150 ybbH K transcriptional
CGAIOGLK_03176 9.8e-234 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CGAIOGLK_03177 1.7e-251 yfeW 3.4.16.4 V Belongs to the UPF0214 family
CGAIOGLK_03178 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
CGAIOGLK_03179 2.7e-238 ybbC 3.2.1.52 S protein conserved in bacteria
CGAIOGLK_03180 2.5e-305 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
CGAIOGLK_03181 1.4e-165 feuA P Iron-uptake system-binding protein
CGAIOGLK_03182 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGAIOGLK_03183 7.4e-178 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGAIOGLK_03184 4.7e-137 ybbA S Putative esterase
CGAIOGLK_03185 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
CGAIOGLK_03187 8.7e-249 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
CGAIOGLK_03189 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
CGAIOGLK_03190 3.2e-92 M1-753 M FR47-like protein
CGAIOGLK_03191 7e-188 yuaG 3.4.21.72 S protein conserved in bacteria
CGAIOGLK_03192 3.3e-73 yuaF OU Membrane protein implicated in regulation of membrane protease activity
CGAIOGLK_03193 8.7e-84 yuaE S DinB superfamily
CGAIOGLK_03194 1.5e-106 yuaD
CGAIOGLK_03195 5.4e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
CGAIOGLK_03196 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
CGAIOGLK_03197 5.5e-95 yuaC K Belongs to the GbsR family
CGAIOGLK_03198 2.2e-91 yuaB
CGAIOGLK_03199 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
CGAIOGLK_03200 1.6e-236 ktrB P Potassium
CGAIOGLK_03201 1e-38 yiaA S yiaA/B two helix domain
CGAIOGLK_03202 1.5e-149 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CGAIOGLK_03203 1.9e-273 yubD P Major Facilitator Superfamily
CGAIOGLK_03204 1.3e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
CGAIOGLK_03206 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
CGAIOGLK_03207 1.3e-194 yubA S transporter activity
CGAIOGLK_03208 3.3e-183 ygjR S Oxidoreductase
CGAIOGLK_03209 4.4e-252 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
CGAIOGLK_03210 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
CGAIOGLK_03211 1.8e-273 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
CGAIOGLK_03212 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
CGAIOGLK_03213 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
CGAIOGLK_03214 2.1e-237 mcpA NT chemotaxis protein
CGAIOGLK_03215 8.5e-295 mcpA NT chemotaxis protein
CGAIOGLK_03216 4.9e-218 mcpA NT chemotaxis protein
CGAIOGLK_03217 1.6e-224 mcpA NT chemotaxis protein
CGAIOGLK_03218 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
CGAIOGLK_03219 1e-35
CGAIOGLK_03220 2.1e-72 yugU S Uncharacterised protein family UPF0047
CGAIOGLK_03221 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
CGAIOGLK_03222 2.9e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
CGAIOGLK_03223 1.4e-116 yugP S Zn-dependent protease
CGAIOGLK_03224 1.1e-35
CGAIOGLK_03225 5.4e-53 mstX S Membrane-integrating protein Mistic
CGAIOGLK_03226 1.1e-181 yugO P COG1226 Kef-type K transport systems
CGAIOGLK_03227 1.3e-72 yugN S YugN-like family
CGAIOGLK_03229 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
CGAIOGLK_03230 3.1e-228 yugK C Dehydrogenase
CGAIOGLK_03231 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
CGAIOGLK_03232 1.1e-34 yuzA S Domain of unknown function (DUF378)
CGAIOGLK_03233 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
CGAIOGLK_03234 6.2e-199 yugH 2.6.1.1 E Aminotransferase
CGAIOGLK_03235 1.6e-85 alaR K Transcriptional regulator
CGAIOGLK_03236 4.9e-156 yugF I Hydrolase
CGAIOGLK_03237 4.6e-39 yugE S Domain of unknown function (DUF1871)
CGAIOGLK_03238 5.4e-225 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
CGAIOGLK_03239 4.6e-233 T PhoQ Sensor
CGAIOGLK_03240 4.1e-68 kapB G Kinase associated protein B
CGAIOGLK_03241 1.9e-115 kapD L the KinA pathway to sporulation
CGAIOGLK_03243 4.2e-184 yuxJ EGP Major facilitator Superfamily
CGAIOGLK_03244 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
CGAIOGLK_03245 1.8e-74 yuxK S protein conserved in bacteria
CGAIOGLK_03246 6.3e-78 yufK S Family of unknown function (DUF5366)
CGAIOGLK_03247 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
CGAIOGLK_03248 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
CGAIOGLK_03249 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
CGAIOGLK_03250 1.6e-272 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
CGAIOGLK_03251 1.4e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
CGAIOGLK_03252 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
CGAIOGLK_03253 8.2e-233 maeN C COG3493 Na citrate symporter
CGAIOGLK_03254 3.2e-14
CGAIOGLK_03255 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
CGAIOGLK_03256 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CGAIOGLK_03257 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CGAIOGLK_03258 1.6e-261 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CGAIOGLK_03259 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CGAIOGLK_03260 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CGAIOGLK_03261 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
CGAIOGLK_03262 2.3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
CGAIOGLK_03263 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CGAIOGLK_03264 9.9e-263 comP 2.7.13.3 T Histidine kinase
CGAIOGLK_03266 3e-141 comQ H Belongs to the FPP GGPP synthase family
CGAIOGLK_03268 8.5e-23 yuzC
CGAIOGLK_03269 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
CGAIOGLK_03270 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CGAIOGLK_03271 9.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
CGAIOGLK_03272 7.9e-67 yueI S Protein of unknown function (DUF1694)
CGAIOGLK_03273 2.8e-38 yueH S YueH-like protein
CGAIOGLK_03274 2.1e-32 yueG S Spore germination protein gerPA/gerPF
CGAIOGLK_03275 4.6e-189 yueF S transporter activity
CGAIOGLK_03276 3.7e-69 S Protein of unknown function (DUF2283)
CGAIOGLK_03277 2.9e-24 S Protein of unknown function (DUF2642)
CGAIOGLK_03278 4.8e-96 yueE S phosphohydrolase
CGAIOGLK_03279 2.2e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CGAIOGLK_03280 7.3e-64 yueC S Family of unknown function (DUF5383)
CGAIOGLK_03281 0.0 esaA S type VII secretion protein EsaA
CGAIOGLK_03282 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
CGAIOGLK_03283 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
CGAIOGLK_03284 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
CGAIOGLK_03285 2.8e-45 esxA S Belongs to the WXG100 family
CGAIOGLK_03286 1.9e-228 yukF QT Transcriptional regulator
CGAIOGLK_03287 3e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
CGAIOGLK_03288 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
CGAIOGLK_03289 5e-36 mbtH S MbtH-like protein
CGAIOGLK_03290 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CGAIOGLK_03291 6.8e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
CGAIOGLK_03292 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
CGAIOGLK_03293 4.3e-225 entC 5.4.4.2 HQ Isochorismate synthase
CGAIOGLK_03294 3.6e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CGAIOGLK_03295 3.9e-167 besA S Putative esterase
CGAIOGLK_03296 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
CGAIOGLK_03297 1.1e-93 bioY S Biotin biosynthesis protein
CGAIOGLK_03298 3.9e-211 yuiF S antiporter
CGAIOGLK_03299 3.4e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CGAIOGLK_03300 1.2e-77 yuiD S protein conserved in bacteria
CGAIOGLK_03301 2.1e-117 yuiC S protein conserved in bacteria
CGAIOGLK_03302 8.4e-27 yuiB S Putative membrane protein
CGAIOGLK_03303 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
CGAIOGLK_03304 2.3e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
CGAIOGLK_03306 6e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CGAIOGLK_03307 1.4e-52
CGAIOGLK_03308 8.5e-113 paiB K Putative FMN-binding domain
CGAIOGLK_03309 6.1e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CGAIOGLK_03310 3.7e-63 erpA S Belongs to the HesB IscA family
CGAIOGLK_03311 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CGAIOGLK_03312 1.2e-198 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CGAIOGLK_03313 3.2e-39 yuzB S Belongs to the UPF0349 family
CGAIOGLK_03314 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
CGAIOGLK_03315 8.7e-56 yuzD S protein conserved in bacteria
CGAIOGLK_03316 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
CGAIOGLK_03317 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
CGAIOGLK_03318 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CGAIOGLK_03319 2e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CGAIOGLK_03320 1e-240 hom 1.1.1.3 E homoserine dehydrogenase
CGAIOGLK_03321 1.4e-197 yutH S Spore coat protein
CGAIOGLK_03322 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
CGAIOGLK_03323 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CGAIOGLK_03324 1e-75 yutE S Protein of unknown function DUF86
CGAIOGLK_03325 9.7e-48 yutD S protein conserved in bacteria
CGAIOGLK_03326 7e-110 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CGAIOGLK_03327 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CGAIOGLK_03328 4.5e-196 lytH M Peptidase, M23
CGAIOGLK_03329 1e-131 yunB S Sporulation protein YunB (Spo_YunB)
CGAIOGLK_03330 4.8e-48 yunC S Domain of unknown function (DUF1805)
CGAIOGLK_03331 1.4e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
CGAIOGLK_03332 5.9e-141 yunE S membrane transporter protein
CGAIOGLK_03333 4.3e-171 yunF S Protein of unknown function DUF72
CGAIOGLK_03334 3e-62 yunG
CGAIOGLK_03335 1.2e-257 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
CGAIOGLK_03336 1.4e-300 pucR QT COG2508 Regulator of polyketide synthase expression
CGAIOGLK_03337 2.2e-230 pbuX F Permease family
CGAIOGLK_03338 2.5e-223 pbuX F xanthine
CGAIOGLK_03339 4e-281 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
CGAIOGLK_03340 2.1e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
CGAIOGLK_03341 6.9e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
CGAIOGLK_03342 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
CGAIOGLK_03343 3.8e-148 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
CGAIOGLK_03344 3.1e-110 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
CGAIOGLK_03345 2.3e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CGAIOGLK_03347 1e-237 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
CGAIOGLK_03348 1.3e-232 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
CGAIOGLK_03349 5e-167 bsn L Ribonuclease
CGAIOGLK_03350 5.9e-205 msmX P Belongs to the ABC transporter superfamily
CGAIOGLK_03351 3.3e-135 yurK K UTRA
CGAIOGLK_03352 1.1e-161 yurL 2.7.1.218 G pfkB family carbohydrate kinase
CGAIOGLK_03353 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
CGAIOGLK_03354 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
CGAIOGLK_03355 3.2e-239 yurO G COG1653 ABC-type sugar transport system, periplasmic component
CGAIOGLK_03356 8.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
CGAIOGLK_03357 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
CGAIOGLK_03358 1.3e-204 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
CGAIOGLK_03360 1e-41
CGAIOGLK_03361 3.5e-271 sufB O FeS cluster assembly
CGAIOGLK_03362 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
CGAIOGLK_03363 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CGAIOGLK_03364 1.4e-245 sufD O assembly protein SufD
CGAIOGLK_03365 8.6e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
CGAIOGLK_03366 9.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CGAIOGLK_03367 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
CGAIOGLK_03368 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
CGAIOGLK_03369 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CGAIOGLK_03370 3.2e-56 yusD S SCP-2 sterol transfer family
CGAIOGLK_03371 5.6e-55 traF CO Thioredoxin
CGAIOGLK_03372 2.1e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
CGAIOGLK_03373 1.1e-39 yusG S Protein of unknown function (DUF2553)
CGAIOGLK_03374 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
CGAIOGLK_03375 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
CGAIOGLK_03376 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
CGAIOGLK_03377 2.7e-216 fadA 2.3.1.16 I Belongs to the thiolase family
CGAIOGLK_03378 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
CGAIOGLK_03379 8.1e-09 S YuzL-like protein
CGAIOGLK_03380 2.4e-164 fadM E Proline dehydrogenase
CGAIOGLK_03381 5.1e-40
CGAIOGLK_03382 5.4e-53 yusN M Coat F domain
CGAIOGLK_03383 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
CGAIOGLK_03384 8.5e-293 yusP P Major facilitator superfamily
CGAIOGLK_03385 6e-64 yusQ S Tautomerase enzyme
CGAIOGLK_03386 2.2e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CGAIOGLK_03387 4.8e-157 yusT K LysR substrate binding domain
CGAIOGLK_03388 1.1e-46 yusU S Protein of unknown function (DUF2573)
CGAIOGLK_03389 3.9e-153 yusV 3.6.3.34 HP ABC transporter
CGAIOGLK_03390 2.5e-66 S YusW-like protein
CGAIOGLK_03391 1.6e-300 pepF2 E COG1164 Oligoendopeptidase F
CGAIOGLK_03392 6e-149 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CGAIOGLK_03393 2.7e-79 dps P Ferritin-like domain
CGAIOGLK_03394 4e-235 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CGAIOGLK_03395 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CGAIOGLK_03396 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
CGAIOGLK_03397 4.3e-158 yuxN K Transcriptional regulator
CGAIOGLK_03398 7.3e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
CGAIOGLK_03399 2.3e-24 S Protein of unknown function (DUF3970)
CGAIOGLK_03400 8.2e-247 gerAA EG Spore germination protein
CGAIOGLK_03401 9.1e-198 gerAB E Spore germination protein
CGAIOGLK_03402 3e-188 gerAC S Spore germination B3/ GerAC like, C-terminal
CGAIOGLK_03403 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CGAIOGLK_03404 3.9e-185 vraS 2.7.13.3 T Histidine kinase
CGAIOGLK_03405 5.6e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
CGAIOGLK_03406 3e-119 liaG S Putative adhesin
CGAIOGLK_03407 9.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
CGAIOGLK_03408 7.3e-62 liaI S membrane
CGAIOGLK_03409 7e-226 yvqJ EGP Major facilitator Superfamily
CGAIOGLK_03410 6.5e-102 yvqK 2.5.1.17 S Adenosyltransferase
CGAIOGLK_03411 8.6e-243 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
CGAIOGLK_03412 1.9e-184 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGAIOGLK_03413 1.5e-169 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
CGAIOGLK_03414 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CGAIOGLK_03415 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
CGAIOGLK_03416 0.0 T PhoQ Sensor
CGAIOGLK_03417 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CGAIOGLK_03418 7.2e-23
CGAIOGLK_03419 9.5e-98 yvrI K RNA polymerase
CGAIOGLK_03420 2.4e-19 S YvrJ protein family
CGAIOGLK_03421 6.8e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
CGAIOGLK_03422 1.3e-64 yvrL S Regulatory protein YrvL
CGAIOGLK_03423 4e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
CGAIOGLK_03424 1.6e-123 macB V ABC transporter, ATP-binding protein
CGAIOGLK_03425 4.8e-176 M Efflux transporter rnd family, mfp subunit
CGAIOGLK_03426 1.3e-148 fhuC 3.6.3.34 HP ABC transporter
CGAIOGLK_03427 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGAIOGLK_03428 6e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGAIOGLK_03429 1.2e-177 fhuD P ABC transporter
CGAIOGLK_03430 1.4e-235 yvsH E Arginine ornithine antiporter
CGAIOGLK_03431 6.5e-16 S Small spore protein J (Spore_SspJ)
CGAIOGLK_03432 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
CGAIOGLK_03433 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
CGAIOGLK_03434 8.6e-165 yvgK P COG1910 Periplasmic molybdate-binding protein domain
CGAIOGLK_03435 1.6e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
CGAIOGLK_03436 6.9e-119 modB P COG4149 ABC-type molybdate transport system, permease component
CGAIOGLK_03437 1.7e-156 yvgN S reductase
CGAIOGLK_03438 4e-84 yvgO
CGAIOGLK_03439 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
CGAIOGLK_03440 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
CGAIOGLK_03441 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CGAIOGLK_03442 0.0 helD 3.6.4.12 L DNA helicase
CGAIOGLK_03444 2.7e-106 yvgT S membrane
CGAIOGLK_03445 8.5e-72 bdbC O Required for disulfide bond formation in some proteins
CGAIOGLK_03446 1.6e-104 bdbD O Thioredoxin
CGAIOGLK_03447 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
CGAIOGLK_03448 0.0 copA 3.6.3.54 P P-type ATPase
CGAIOGLK_03449 5.9e-29 copZ P Copper resistance protein CopZ
CGAIOGLK_03450 2.2e-48 csoR S transcriptional
CGAIOGLK_03451 3.1e-195 yvaA 1.1.1.371 S Oxidoreductase
CGAIOGLK_03452 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CGAIOGLK_03453 0.0 yvaC S Fusaric acid resistance protein-like
CGAIOGLK_03454 5.7e-73 yvaD S Family of unknown function (DUF5360)
CGAIOGLK_03455 8.2e-55 yvaE P Small Multidrug Resistance protein
CGAIOGLK_03456 9.5e-98 K Bacterial regulatory proteins, tetR family
CGAIOGLK_03457 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CGAIOGLK_03459 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CGAIOGLK_03460 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CGAIOGLK_03461 5.6e-143 est 3.1.1.1 S Carboxylesterase
CGAIOGLK_03462 2.4e-23 secG U Preprotein translocase subunit SecG
CGAIOGLK_03463 2.2e-150 yvaM S Serine aminopeptidase, S33
CGAIOGLK_03464 7.5e-36 yvzC K Transcriptional
CGAIOGLK_03465 4e-69 K transcriptional
CGAIOGLK_03466 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
CGAIOGLK_03467 2.2e-54 yodB K transcriptional
CGAIOGLK_03468 7.9e-225 NT chemotaxis protein
CGAIOGLK_03469 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
CGAIOGLK_03470 5.2e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
CGAIOGLK_03471 7.3e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
CGAIOGLK_03472 4.4e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
CGAIOGLK_03473 7.4e-60 yvbF K Belongs to the GbsR family
CGAIOGLK_03474 1.1e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
CGAIOGLK_03475 1.8e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
CGAIOGLK_03476 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
CGAIOGLK_03477 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
CGAIOGLK_03478 3.5e-97 yvbF K Belongs to the GbsR family
CGAIOGLK_03479 7.6e-56 yvbG U UPF0056 membrane protein
CGAIOGLK_03480 4.4e-13 yvbG U UPF0056 membrane protein
CGAIOGLK_03481 2.5e-112 yvbH S YvbH-like oligomerisation region
CGAIOGLK_03482 8e-123 exoY M Membrane
CGAIOGLK_03483 0.0 tcaA S response to antibiotic
CGAIOGLK_03484 3.8e-81 yvbK 3.1.3.25 K acetyltransferase
CGAIOGLK_03485 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CGAIOGLK_03486 3.7e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
CGAIOGLK_03487 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CGAIOGLK_03488 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
CGAIOGLK_03489 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CGAIOGLK_03490 9.1e-184 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
CGAIOGLK_03491 1.6e-252 araE EGP Major facilitator Superfamily
CGAIOGLK_03492 3.5e-202 araR K transcriptional
CGAIOGLK_03493 5.8e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGAIOGLK_03494 2.5e-158 yvbU K Transcriptional regulator
CGAIOGLK_03495 1.6e-155 yvbV EG EamA-like transporter family
CGAIOGLK_03496 4.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
CGAIOGLK_03497 4.3e-197 yvbX S Glycosyl hydrolase
CGAIOGLK_03498 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
CGAIOGLK_03499 2.7e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
CGAIOGLK_03500 4.2e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
CGAIOGLK_03501 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CGAIOGLK_03502 2e-200 desK 2.7.13.3 T Histidine kinase
CGAIOGLK_03503 1.4e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
CGAIOGLK_03504 6.6e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
CGAIOGLK_03505 2.9e-156 rsbQ S Alpha/beta hydrolase family
CGAIOGLK_03506 8.5e-197 rsbU 3.1.3.3 T response regulator
CGAIOGLK_03507 9.2e-250 galA 3.2.1.89 G arabinogalactan
CGAIOGLK_03508 0.0 lacA 3.2.1.23 G beta-galactosidase
CGAIOGLK_03509 1.2e-149 ganQ P transport
CGAIOGLK_03510 1.1e-231 malC P COG1175 ABC-type sugar transport systems, permease components
CGAIOGLK_03511 2.6e-228 cycB G COG2182 Maltose-binding periplasmic proteins domains
CGAIOGLK_03512 5.2e-184 lacR K Transcriptional regulator
CGAIOGLK_03513 2.7e-113 yvfI K COG2186 Transcriptional regulators
CGAIOGLK_03514 7e-306 yvfH C L-lactate permease
CGAIOGLK_03515 6.7e-240 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
CGAIOGLK_03516 1e-31 yvfG S YvfG protein
CGAIOGLK_03517 9.2e-186 yvfF GM Exopolysaccharide biosynthesis protein
CGAIOGLK_03518 6.9e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
CGAIOGLK_03519 2.1e-56 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
CGAIOGLK_03520 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
CGAIOGLK_03521 1.3e-258 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CGAIOGLK_03522 5.2e-195 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
CGAIOGLK_03523 4.4e-205 epsI GM pyruvyl transferase
CGAIOGLK_03524 2e-194 epsH GT2 S Glycosyltransferase like family 2
CGAIOGLK_03525 1.1e-206 epsG S EpsG family
CGAIOGLK_03526 1.6e-216 epsF GT4 M Glycosyl transferases group 1
CGAIOGLK_03527 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
CGAIOGLK_03528 3.8e-223 epsD GT4 M Glycosyl transferase 4-like
CGAIOGLK_03529 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
CGAIOGLK_03530 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
CGAIOGLK_03531 4e-122 ywqC M biosynthesis protein
CGAIOGLK_03532 6.3e-76 slr K transcriptional
CGAIOGLK_03533 3.3e-280 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
CGAIOGLK_03535 1.7e-92 padC Q Phenolic acid decarboxylase
CGAIOGLK_03536 6.5e-73 MA20_18690 S Protein of unknown function (DUF3237)
CGAIOGLK_03537 3.4e-126 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
CGAIOGLK_03538 1.9e-261 pbpE V Beta-lactamase
CGAIOGLK_03539 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
CGAIOGLK_03540 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
CGAIOGLK_03541 3.9e-295 yveA E amino acid
CGAIOGLK_03542 2.6e-106 yvdT K Transcriptional regulator
CGAIOGLK_03543 6.7e-51 ykkC P Small Multidrug Resistance protein
CGAIOGLK_03544 4.1e-50 sugE P Small Multidrug Resistance protein
CGAIOGLK_03545 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
CGAIOGLK_03546 1.1e-269 ygaK C COG0277 FAD FMN-containing dehydrogenases
CGAIOGLK_03547 2.8e-182 S Patatin-like phospholipase
CGAIOGLK_03549 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CGAIOGLK_03550 1.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
CGAIOGLK_03551 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
CGAIOGLK_03552 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
CGAIOGLK_03553 1.1e-153 malA S Protein of unknown function (DUF1189)
CGAIOGLK_03554 1.6e-146 malD P transport
CGAIOGLK_03555 3.8e-243 malC P COG1175 ABC-type sugar transport systems, permease components
CGAIOGLK_03557 3.6e-99 L endonuclease activity
CGAIOGLK_03558 2.3e-50
CGAIOGLK_03559 1.6e-210 S Tetratricopeptide repeat
CGAIOGLK_03561 2.7e-126 yeeN K transcriptional regulatory protein
CGAIOGLK_03563 9.4e-101 dhaR3 K Transcriptional regulator
CGAIOGLK_03564 3.7e-81 yesE S SnoaL-like domain
CGAIOGLK_03565 1.3e-151 yesF GM NAD(P)H-binding
CGAIOGLK_03566 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
CGAIOGLK_03567 1.5e-45 cotJB S CotJB protein
CGAIOGLK_03568 5.2e-104 cotJC P Spore Coat
CGAIOGLK_03569 1.5e-100 yesJ K Acetyltransferase (GNAT) family
CGAIOGLK_03571 1.7e-100 yesL S Protein of unknown function, DUF624
CGAIOGLK_03572 0.0 yesM 2.7.13.3 T Histidine kinase
CGAIOGLK_03573 1.4e-201 yesN K helix_turn_helix, arabinose operon control protein
CGAIOGLK_03574 3.6e-246 yesO G Bacterial extracellular solute-binding protein
CGAIOGLK_03575 6.9e-167 yesP G Binding-protein-dependent transport system inner membrane component
CGAIOGLK_03576 2.4e-164 yesQ P Binding-protein-dependent transport system inner membrane component
CGAIOGLK_03577 2.9e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
CGAIOGLK_03578 0.0 yesS K Transcriptional regulator
CGAIOGLK_03579 7.4e-129 E GDSL-like Lipase/Acylhydrolase
CGAIOGLK_03580 1.7e-127 yesU S Domain of unknown function (DUF1961)
CGAIOGLK_03581 5.7e-112 yesV S Protein of unknown function, DUF624
CGAIOGLK_03582 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
CGAIOGLK_03583 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
CGAIOGLK_03584 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
CGAIOGLK_03585 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
CGAIOGLK_03586 0.0 yetA
CGAIOGLK_03587 8.2e-290 lplA G Bacterial extracellular solute-binding protein
CGAIOGLK_03588 1.5e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
CGAIOGLK_03589 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
CGAIOGLK_03590 3.5e-252 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
CGAIOGLK_03591 8.8e-122 yetF S membrane
CGAIOGLK_03592 3.7e-54 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
CGAIOGLK_03593 7.4e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CGAIOGLK_03594 2.2e-34
CGAIOGLK_03595 2.4e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CGAIOGLK_03596 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
CGAIOGLK_03597 2.6e-104 yetJ S Belongs to the BI1 family
CGAIOGLK_03598 5e-157 yetK EG EamA-like transporter family
CGAIOGLK_03599 4.6e-88 yetL K helix_turn_helix multiple antibiotic resistance protein
CGAIOGLK_03600 5.5e-65 yetM CH FAD binding domain
CGAIOGLK_03601 7e-124 yetM CH FAD binding domain
CGAIOGLK_03602 1.8e-198 yetN S Protein of unknown function (DUF3900)
CGAIOGLK_03603 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
CGAIOGLK_03604 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
CGAIOGLK_03605 9.6e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
CGAIOGLK_03606 4.1e-186 yfnG 4.2.1.45 M dehydratase
CGAIOGLK_03607 6e-179 yfnF M Nucleotide-diphospho-sugar transferase
CGAIOGLK_03608 3e-223 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
CGAIOGLK_03609 3.9e-189 yfnD M Nucleotide-diphospho-sugar transferase
CGAIOGLK_03610 1.7e-205 fsr P COG0477 Permeases of the major facilitator superfamily
CGAIOGLK_03611 1.8e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
CGAIOGLK_03612 1.4e-240 yfnA E amino acid
CGAIOGLK_03613 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CGAIOGLK_03614 1.1e-113 yfmS NT chemotaxis protein
CGAIOGLK_03615 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
CGAIOGLK_03616 4.9e-73 yfmQ S Uncharacterised protein from bacillus cereus group
CGAIOGLK_03617 2.4e-69 yfmP K transcriptional
CGAIOGLK_03618 1.5e-209 yfmO EGP Major facilitator Superfamily
CGAIOGLK_03619 7.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
CGAIOGLK_03620 2.9e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
CGAIOGLK_03621 6.8e-75 yfmK 2.3.1.128 K acetyltransferase
CGAIOGLK_03622 2.5e-189 yfmJ S N-terminal domain of oxidoreductase
CGAIOGLK_03623 2e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
CGAIOGLK_03624 2.1e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGAIOGLK_03625 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGAIOGLK_03626 7.9e-166 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
CGAIOGLK_03627 5e-24 S Protein of unknown function (DUF3212)
CGAIOGLK_03628 7.6e-58 yflT S Heat induced stress protein YflT
CGAIOGLK_03629 1.1e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
CGAIOGLK_03630 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
CGAIOGLK_03631 1.5e-289 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
CGAIOGLK_03632 4.4e-118 citT T response regulator
CGAIOGLK_03633 8.3e-179 yflP S Tripartite tricarboxylate transporter family receptor
CGAIOGLK_03634 8.5e-227 citM C Citrate transporter
CGAIOGLK_03635 1.8e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
CGAIOGLK_03636 1.3e-215 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CGAIOGLK_03637 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
CGAIOGLK_03638 1.7e-122 yflK S protein conserved in bacteria
CGAIOGLK_03639 8.9e-18 yflJ S Protein of unknown function (DUF2639)
CGAIOGLK_03640 1.6e-18 yflI
CGAIOGLK_03641 5.3e-50 yflH S Protein of unknown function (DUF3243)
CGAIOGLK_03642 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
CGAIOGLK_03643 1.5e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
CGAIOGLK_03644 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
CGAIOGLK_03645 6e-67 yhdN S Domain of unknown function (DUF1992)
CGAIOGLK_03646 1.1e-251 agcS_1 E Sodium alanine symporter
CGAIOGLK_03647 8.6e-193 E Spore germination protein
CGAIOGLK_03649 3.3e-206 yfkR S spore germination
CGAIOGLK_03650 2.4e-281 yfkQ EG Spore germination protein
CGAIOGLK_03651 2.5e-256 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CGAIOGLK_03652 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
CGAIOGLK_03653 1.8e-133 treR K transcriptional
CGAIOGLK_03654 1.1e-124 yfkO C nitroreductase
CGAIOGLK_03655 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
CGAIOGLK_03656 1.2e-88 yfkM 1.11.1.6, 3.5.1.124 S protease
CGAIOGLK_03657 3.4e-206 ydiM EGP Major facilitator Superfamily
CGAIOGLK_03658 2.1e-29 yfkK S Belongs to the UPF0435 family
CGAIOGLK_03659 1e-81 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CGAIOGLK_03660 7.1e-50 yfkI S gas vesicle protein
CGAIOGLK_03661 2.8e-143 yihY S Belongs to the UPF0761 family
CGAIOGLK_03662 5e-08
CGAIOGLK_03663 2e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
CGAIOGLK_03664 1.8e-182 cax P COG0387 Ca2 H antiporter
CGAIOGLK_03665 4.5e-146 yfkD S YfkD-like protein
CGAIOGLK_03666 6e-149 yfkC M Mechanosensitive ion channel
CGAIOGLK_03667 5.4e-222 yfkA S YfkB-like domain
CGAIOGLK_03668 1.1e-26 yfjT
CGAIOGLK_03669 2.6e-154 pdaA G deacetylase
CGAIOGLK_03670 2.1e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
CGAIOGLK_03671 1.7e-184 corA P Mediates influx of magnesium ions
CGAIOGLK_03672 2.2e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CGAIOGLK_03673 2e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CGAIOGLK_03674 3.9e-44 S YfzA-like protein
CGAIOGLK_03675 3.1e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CGAIOGLK_03676 6.2e-84 yfjM S Psort location Cytoplasmic, score
CGAIOGLK_03677 4.4e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
CGAIOGLK_03678 7.2e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CGAIOGLK_03679 6.7e-194 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CGAIOGLK_03680 2.3e-254 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
CGAIOGLK_03681 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
CGAIOGLK_03682 9.8e-25 sspH S Belongs to the SspH family
CGAIOGLK_03683 4e-56 yfjF S UPF0060 membrane protein
CGAIOGLK_03684 6.2e-86 S Family of unknown function (DUF5381)
CGAIOGLK_03685 2.3e-123 yfjC
CGAIOGLK_03686 9.6e-172 yfjB
CGAIOGLK_03687 2.6e-44 yfjA S Belongs to the WXG100 family
CGAIOGLK_03688 4.9e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
CGAIOGLK_03689 1e-139 glvR K Helix-turn-helix domain, rpiR family
CGAIOGLK_03690 2.3e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CGAIOGLK_03691 3.8e-307 yfiB3 V ABC transporter
CGAIOGLK_03692 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
CGAIOGLK_03693 6.4e-64 mhqP S DoxX
CGAIOGLK_03694 2.2e-162 yfiE 1.13.11.2 S glyoxalase
CGAIOGLK_03696 1.8e-212 yxjM T Histidine kinase
CGAIOGLK_03697 6e-112 KT LuxR family transcriptional regulator
CGAIOGLK_03698 2.4e-167 V ABC transporter, ATP-binding protein
CGAIOGLK_03699 8.1e-208 V ABC-2 family transporter protein
CGAIOGLK_03700 3.2e-201 V COG0842 ABC-type multidrug transport system, permease component
CGAIOGLK_03701 8.3e-99 padR K transcriptional
CGAIOGLK_03702 1.7e-79 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
CGAIOGLK_03703 4.5e-197 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
CGAIOGLK_03704 2.4e-98 yfiT S Belongs to the metal hydrolase YfiT family
CGAIOGLK_03705 6.9e-284 yfiU EGP Major facilitator Superfamily
CGAIOGLK_03706 1.4e-78 yfiV K transcriptional
CGAIOGLK_03707 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CGAIOGLK_03708 1.8e-176 yfiY P ABC transporter substrate-binding protein
CGAIOGLK_03709 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGAIOGLK_03710 6.8e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGAIOGLK_03711 1.4e-164 yfhB 5.3.3.17 S PhzF family
CGAIOGLK_03712 3.9e-107 yfhC C nitroreductase
CGAIOGLK_03713 8e-25 yfhD S YfhD-like protein
CGAIOGLK_03715 2.1e-171 yfhF S nucleoside-diphosphate sugar epimerase
CGAIOGLK_03716 4.8e-140 recX 2.4.1.337 GT4 S Modulates RecA activity
CGAIOGLK_03717 9.7e-52 yfhH S Protein of unknown function (DUF1811)
CGAIOGLK_03718 1.5e-209 yfhI EGP Major facilitator Superfamily
CGAIOGLK_03719 6.2e-20 sspK S reproduction
CGAIOGLK_03720 1.3e-44 yfhJ S WVELL protein
CGAIOGLK_03721 1e-90 batE T Bacterial SH3 domain homologues
CGAIOGLK_03722 6.6e-50 yfhL S SdpI/YhfL protein family
CGAIOGLK_03723 2.8e-170 yfhM S Alpha beta hydrolase
CGAIOGLK_03724 1.4e-184 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
CGAIOGLK_03725 0.0 yfhO S Bacterial membrane protein YfhO
CGAIOGLK_03726 5.5e-186 yfhP S membrane-bound metal-dependent
CGAIOGLK_03727 9.5e-210 mutY L A G-specific
CGAIOGLK_03728 6.9e-36 yfhS
CGAIOGLK_03729 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CGAIOGLK_03730 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
CGAIOGLK_03731 1.5e-37 ygaB S YgaB-like protein
CGAIOGLK_03732 1.3e-104 ygaC J Belongs to the UPF0374 family
CGAIOGLK_03733 1.8e-301 ygaD V ABC transporter
CGAIOGLK_03734 8.7e-180 ygaE S Membrane
CGAIOGLK_03735 2.6e-244 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
CGAIOGLK_03736 8.2e-87 bcp 1.11.1.15 O Peroxiredoxin
CGAIOGLK_03737 4e-80 perR P Belongs to the Fur family
CGAIOGLK_03738 9.5e-56 ygzB S UPF0295 protein
CGAIOGLK_03739 4.3e-166 ygxA S Nucleotidyltransferase-like
CGAIOGLK_03740 0.0 L nucleic acid phosphodiester bond hydrolysis
CGAIOGLK_03741 4.5e-53 S Protein of unknown function, DUF600
CGAIOGLK_03742 1.3e-55 S Protein of unknown function, DUF600
CGAIOGLK_03743 1.9e-11 S Protein of unknown function, DUF600
CGAIOGLK_03744 1.3e-54
CGAIOGLK_03745 3.5e-07
CGAIOGLK_03746 4.9e-107 S WLM domain
CGAIOGLK_03747 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
CGAIOGLK_03748 1.9e-95 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
CGAIOGLK_03749 5.6e-270 hsdM 2.1.1.72 V Type I restriction-modification system
CGAIOGLK_03750 6.8e-70 hsdS2 2.1.1.72 V type I restriction modification DNA specificity domain
CGAIOGLK_03751 1.3e-249 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CGAIOGLK_03752 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
CGAIOGLK_03753 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CGAIOGLK_03754 1.1e-147 yerO K Transcriptional regulator
CGAIOGLK_03755 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CGAIOGLK_03756 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CGAIOGLK_03757 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CGAIOGLK_03758 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGAIOGLK_03759 1.6e-123 sapB S MgtC SapB transporter
CGAIOGLK_03760 3.3e-194 yerI S homoserine kinase type II (protein kinase fold)
CGAIOGLK_03761 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
CGAIOGLK_03762 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CGAIOGLK_03763 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
CGAIOGLK_03764 4.9e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CGAIOGLK_03765 1.5e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
CGAIOGLK_03766 4.8e-51 yerC S protein conserved in bacteria
CGAIOGLK_03767 1.1e-189 yerB S Protein of unknown function (DUF3048) C-terminal domain
CGAIOGLK_03768 0.0 yerA 3.5.4.2 F adenine deaminase
CGAIOGLK_03769 2.7e-27 S Protein of unknown function (DUF2892)
CGAIOGLK_03770 1.4e-229 yjeH E Amino acid permease
CGAIOGLK_03771 7.3e-71 K helix_turn_helix ASNC type
CGAIOGLK_03772 7e-234 purD 6.3.4.13 F Belongs to the GARS family
CGAIOGLK_03773 6e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
CGAIOGLK_03774 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CGAIOGLK_03775 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
CGAIOGLK_03776 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CGAIOGLK_03777 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CGAIOGLK_03778 1.9e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CGAIOGLK_03779 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CGAIOGLK_03780 2.8e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
CGAIOGLK_03781 1.3e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CGAIOGLK_03782 3.8e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CGAIOGLK_03783 7.4e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CGAIOGLK_03784 8e-28 yebG S NETI protein
CGAIOGLK_03785 4e-93 yebE S UPF0316 protein
CGAIOGLK_03787 4.4e-117 yebC M Membrane
CGAIOGLK_03788 1.1e-210 pbuG S permease
CGAIOGLK_03789 2.7e-245 S Domain of unknown function (DUF4179)
CGAIOGLK_03790 2.6e-89 K Belongs to the sigma-70 factor family. ECF subfamily
CGAIOGLK_03791 8.3e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
CGAIOGLK_03792 0.0 yebA E COG1305 Transglutaminase-like enzymes
CGAIOGLK_03793 1.2e-224 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
CGAIOGLK_03794 1.9e-175 yeaC S COG0714 MoxR-like ATPases
CGAIOGLK_03796 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CGAIOGLK_03797 5.7e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
CGAIOGLK_03798 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
CGAIOGLK_03799 8e-177 yeaA S Protein of unknown function (DUF4003)
CGAIOGLK_03800 7.6e-157 ydjP I Alpha/beta hydrolase family
CGAIOGLK_03801 1.2e-34 ydjO S Cold-inducible protein YdjO
CGAIOGLK_03803 5.3e-155 ydjN U Involved in the tonB-independent uptake of proteins
CGAIOGLK_03804 4.5e-64 ydjM M Lytic transglycolase
CGAIOGLK_03805 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
CGAIOGLK_03806 1.7e-257 iolT EGP Major facilitator Superfamily
CGAIOGLK_03807 1.1e-149 S Ion transport 2 domain protein
CGAIOGLK_03808 1.2e-148 ydjI S virion core protein (lumpy skin disease virus)
CGAIOGLK_03809 7.1e-133 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
CGAIOGLK_03810 9.8e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CGAIOGLK_03811 8.7e-114 pspA KT Phage shock protein A
CGAIOGLK_03812 2.2e-171 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
CGAIOGLK_03813 1.5e-250 gutA G MFS/sugar transport protein
CGAIOGLK_03814 5.2e-198 gutB 1.1.1.14 E Dehydrogenase
CGAIOGLK_03815 0.0 K NB-ARC domain
CGAIOGLK_03816 2.6e-151 ydjC S Abhydrolase domain containing 18
CGAIOGLK_03817 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CGAIOGLK_03818 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CGAIOGLK_03819 7.9e-129 ydiL S CAAX protease self-immunity
CGAIOGLK_03820 2.9e-27 ydiK S Domain of unknown function (DUF4305)
CGAIOGLK_03821 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CGAIOGLK_03822 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
CGAIOGLK_03823 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CGAIOGLK_03824 7.2e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
CGAIOGLK_03825 0.0 ydiF S ABC transporter
CGAIOGLK_03826 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CGAIOGLK_03827 1.1e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
CGAIOGLK_03828 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
CGAIOGLK_03829 5.9e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
CGAIOGLK_03830 7.1e-178 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CGAIOGLK_03832 7.8e-08
CGAIOGLK_03833 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
CGAIOGLK_03834 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
CGAIOGLK_03835 4.5e-84 gerD
CGAIOGLK_03836 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
CGAIOGLK_03837 7.4e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
CGAIOGLK_03838 9.7e-66 ybaK S Protein of unknown function (DUF2521)
CGAIOGLK_03839 2.4e-144 ybaJ Q Methyltransferase domain
CGAIOGLK_03840 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
CGAIOGLK_03841 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CGAIOGLK_03842 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CGAIOGLK_03843 1e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CGAIOGLK_03844 5.4e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CGAIOGLK_03845 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CGAIOGLK_03846 3.6e-58 rplQ J Ribosomal protein L17
CGAIOGLK_03847 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CGAIOGLK_03848 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CGAIOGLK_03849 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CGAIOGLK_03850 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
CGAIOGLK_03851 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CGAIOGLK_03852 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
CGAIOGLK_03853 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CGAIOGLK_03854 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CGAIOGLK_03855 1.8e-72 rplO J binds to the 23S rRNA
CGAIOGLK_03856 1.9e-23 rpmD J Ribosomal protein L30
CGAIOGLK_03857 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CGAIOGLK_03858 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CGAIOGLK_03859 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CGAIOGLK_03860 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CGAIOGLK_03861 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CGAIOGLK_03862 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CGAIOGLK_03863 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CGAIOGLK_03864 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CGAIOGLK_03865 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CGAIOGLK_03866 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
CGAIOGLK_03867 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CGAIOGLK_03868 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CGAIOGLK_03869 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CGAIOGLK_03870 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CGAIOGLK_03871 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CGAIOGLK_03872 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CGAIOGLK_03873 3e-105 rplD J Forms part of the polypeptide exit tunnel
CGAIOGLK_03874 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CGAIOGLK_03875 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
CGAIOGLK_03876 3.3e-180 ybaC 3.4.11.5 S Alpha/beta hydrolase family
CGAIOGLK_03877 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CGAIOGLK_03878 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CGAIOGLK_03879 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CGAIOGLK_03880 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CGAIOGLK_03881 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
CGAIOGLK_03882 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CGAIOGLK_03883 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CGAIOGLK_03884 4.5e-106 rsmC 2.1.1.172 J Methyltransferase
CGAIOGLK_03885 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CGAIOGLK_03886 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CGAIOGLK_03887 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CGAIOGLK_03888 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CGAIOGLK_03889 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
CGAIOGLK_03890 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CGAIOGLK_03891 4.4e-115 sigH K Belongs to the sigma-70 factor family
CGAIOGLK_03892 4.7e-88 yacP S RNA-binding protein containing a PIN domain
CGAIOGLK_03893 2.2e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CGAIOGLK_03894 3e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CGAIOGLK_03895 3.2e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
CGAIOGLK_03896 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
CGAIOGLK_03897 3.3e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CGAIOGLK_03898 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
CGAIOGLK_03899 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
CGAIOGLK_03900 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
CGAIOGLK_03901 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CGAIOGLK_03902 3.6e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CGAIOGLK_03903 0.0 clpC O Belongs to the ClpA ClpB family
CGAIOGLK_03904 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
CGAIOGLK_03905 3.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
CGAIOGLK_03906 2.9e-76 ctsR K Belongs to the CtsR family
CGAIOGLK_03907 3.4e-31 csfB S Inhibitor of sigma-G Gin
CGAIOGLK_03908 4.4e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
CGAIOGLK_03909 2.4e-201 yaaN P Belongs to the TelA family
CGAIOGLK_03910 1.3e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
CGAIOGLK_03911 2.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CGAIOGLK_03912 2.2e-54 yaaQ S protein conserved in bacteria
CGAIOGLK_03913 1.5e-71 yaaR S protein conserved in bacteria
CGAIOGLK_03914 1.1e-181 holB 2.7.7.7 L DNA polymerase III
CGAIOGLK_03915 6.1e-146 yaaT S stage 0 sporulation protein
CGAIOGLK_03916 4.8e-31 yabA L Involved in initiation control of chromosome replication
CGAIOGLK_03917 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
CGAIOGLK_03918 1.5e-49 yazA L endonuclease containing a URI domain
CGAIOGLK_03919 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CGAIOGLK_03920 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
CGAIOGLK_03921 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CGAIOGLK_03922 1.2e-143 tatD L hydrolase, TatD
CGAIOGLK_03923 7.6e-167 rpfB GH23 T protein conserved in bacteria
CGAIOGLK_03924 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CGAIOGLK_03925 4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CGAIOGLK_03926 1.6e-136 yabG S peptidase
CGAIOGLK_03927 7.8e-39 veg S protein conserved in bacteria
CGAIOGLK_03928 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CGAIOGLK_03929 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
CGAIOGLK_03930 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
CGAIOGLK_03931 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
CGAIOGLK_03932 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CGAIOGLK_03933 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CGAIOGLK_03934 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CGAIOGLK_03935 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CGAIOGLK_03936 2.4e-39 yabK S Peptide ABC transporter permease
CGAIOGLK_03937 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CGAIOGLK_03938 1.5e-92 spoVT K stage V sporulation protein
CGAIOGLK_03939 7.6e-286 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CGAIOGLK_03940 7.8e-245 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
CGAIOGLK_03941 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
CGAIOGLK_03942 1.5e-49 yabP S Sporulation protein YabP
CGAIOGLK_03943 4.3e-107 yabQ S spore cortex biosynthesis protein
CGAIOGLK_03944 1.1e-44 divIC D Septum formation initiator
CGAIOGLK_03945 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
CGAIOGLK_03948 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
CGAIOGLK_03949 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
CGAIOGLK_03950 1.1e-184 KLT serine threonine protein kinase
CGAIOGLK_03951 1.2e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CGAIOGLK_03952 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
CGAIOGLK_03953 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CGAIOGLK_03954 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CGAIOGLK_03955 4.2e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CGAIOGLK_03956 1.7e-134 yacD 5.2.1.8 O peptidyl-prolyl isomerase
CGAIOGLK_03957 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CGAIOGLK_03958 1.4e-267 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CGAIOGLK_03959 4.3e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
CGAIOGLK_03960 2.3e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
CGAIOGLK_03961 8.5e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CGAIOGLK_03962 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CGAIOGLK_03963 1.8e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CGAIOGLK_03964 4.1e-30 yazB K transcriptional
CGAIOGLK_03965 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CGAIOGLK_03966 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
CGAIOGLK_03967 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
CGAIOGLK_03968 7.9e-32 yaaL S Protein of unknown function (DUF2508)
CGAIOGLK_03969 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CGAIOGLK_03970 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CGAIOGLK_03971 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CGAIOGLK_03972 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CGAIOGLK_03973 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
CGAIOGLK_03974 3.6e-214 yaaH M Glycoside Hydrolase Family
CGAIOGLK_03975 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
CGAIOGLK_03976 2.4e-121 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
CGAIOGLK_03977 1.3e-09
CGAIOGLK_03978 2.5e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CGAIOGLK_03979 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CGAIOGLK_03980 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CGAIOGLK_03981 6.8e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CGAIOGLK_03982 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
CGAIOGLK_03983 3e-181 yaaC S YaaC-like Protein
CGAIOGLK_03984 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CGAIOGLK_03985 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CGAIOGLK_03986 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CGAIOGLK_03987 3.4e-39 S COG NOG14552 non supervised orthologous group
CGAIOGLK_03992 2e-08
CGAIOGLK_04001 7.8e-08
CGAIOGLK_04004 2e-08

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)