ORF_ID e_value Gene_name EC_number CAZy COGs Description
NDOFGNNI_00005 7.8e-08
NDOFGNNI_00013 2e-08
NDOFGNNI_00017 2.7e-143 spo0M S COG4326 Sporulation control protein
NDOFGNNI_00018 3e-27
NDOFGNNI_00019 4.7e-131 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
NDOFGNNI_00020 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NDOFGNNI_00021 2.2e-262 ygaK C Berberine and berberine like
NDOFGNNI_00023 1e-289 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NDOFGNNI_00024 2.5e-138 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NDOFGNNI_00025 1.2e-169 ssuA M Sulfonate ABC transporter
NDOFGNNI_00026 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NDOFGNNI_00027 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
NDOFGNNI_00029 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NDOFGNNI_00030 9.1e-78 ygaO
NDOFGNNI_00031 4.4e-29 K Transcriptional regulator
NDOFGNNI_00033 7.9e-114 yhzB S B3/4 domain
NDOFGNNI_00034 2.3e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NDOFGNNI_00035 4.8e-176 yhbB S Putative amidase domain
NDOFGNNI_00036 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NDOFGNNI_00037 1.2e-109 yhbD K Protein of unknown function (DUF4004)
NDOFGNNI_00038 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
NDOFGNNI_00039 8.2e-75 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
NDOFGNNI_00040 0.0 prkA T Ser protein kinase
NDOFGNNI_00041 2.5e-225 yhbH S Belongs to the UPF0229 family
NDOFGNNI_00042 2.2e-76 yhbI K DNA-binding transcription factor activity
NDOFGNNI_00043 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
NDOFGNNI_00044 3.1e-271 yhcA EGP Major facilitator Superfamily
NDOFGNNI_00045 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
NDOFGNNI_00046 2.8e-37 yhcC
NDOFGNNI_00047 7.8e-55
NDOFGNNI_00048 6.6e-60 yhcF K Transcriptional regulator
NDOFGNNI_00049 1.6e-123 yhcG V ABC transporter, ATP-binding protein
NDOFGNNI_00050 2.6e-166 yhcH V ABC transporter, ATP-binding protein
NDOFGNNI_00051 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NDOFGNNI_00052 1e-30 cspB K Cold-shock protein
NDOFGNNI_00053 6.3e-151 metQ M Belongs to the nlpA lipoprotein family
NDOFGNNI_00054 6.9e-170 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
NDOFGNNI_00055 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NDOFGNNI_00056 1.1e-40 yhcM
NDOFGNNI_00057 6e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NDOFGNNI_00058 6.2e-166 yhcP
NDOFGNNI_00059 5.2e-100 yhcQ M Spore coat protein
NDOFGNNI_00060 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
NDOFGNNI_00061 7.6e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
NDOFGNNI_00062 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NDOFGNNI_00063 9.3e-68 yhcU S Family of unknown function (DUF5365)
NDOFGNNI_00064 9.9e-68 yhcV S COG0517 FOG CBS domain
NDOFGNNI_00065 4.6e-120 yhcW 5.4.2.6 S hydrolase
NDOFGNNI_00066 4.6e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NDOFGNNI_00067 1.2e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NDOFGNNI_00068 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NDOFGNNI_00069 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
NDOFGNNI_00070 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NDOFGNNI_00071 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NDOFGNNI_00072 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
NDOFGNNI_00073 5.5e-214 yhcY 2.7.13.3 T Histidine kinase
NDOFGNNI_00074 1.4e-110 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NDOFGNNI_00075 9.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
NDOFGNNI_00076 1.2e-38 yhdB S YhdB-like protein
NDOFGNNI_00077 4.8e-54 yhdC S Protein of unknown function (DUF3889)
NDOFGNNI_00078 9e-185 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NDOFGNNI_00079 1e-75 nsrR K Transcriptional regulator
NDOFGNNI_00080 1.5e-238 ygxB M Conserved TM helix
NDOFGNNI_00081 2.1e-276 ycgB S Stage V sporulation protein R
NDOFGNNI_00082 8.3e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NDOFGNNI_00083 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NDOFGNNI_00084 3.8e-162 citR K Transcriptional regulator
NDOFGNNI_00085 4.7e-202 citA 2.3.3.1 C Belongs to the citrate synthase family
NDOFGNNI_00086 7.8e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NDOFGNNI_00087 3.4e-250 yhdG E amino acid
NDOFGNNI_00088 5.7e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NDOFGNNI_00089 3.3e-269 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NDOFGNNI_00090 4.5e-76 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NDOFGNNI_00091 8.1e-45 yhdK S Sigma-M inhibitor protein
NDOFGNNI_00092 2.5e-200 yhdL S Sigma factor regulator N-terminal
NDOFGNNI_00093 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
NDOFGNNI_00094 2.6e-191 yhdN C Aldo keto reductase
NDOFGNNI_00095 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NDOFGNNI_00096 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NDOFGNNI_00097 4.1e-74 cueR K transcriptional
NDOFGNNI_00098 4.4e-222 yhdR 2.6.1.1 E Aminotransferase
NDOFGNNI_00099 3.3e-245 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
NDOFGNNI_00100 4.6e-42 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NDOFGNNI_00101 6.2e-64 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NDOFGNNI_00102 1.2e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NDOFGNNI_00104 5.6e-203 yhdY M Mechanosensitive ion channel
NDOFGNNI_00105 1.2e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NDOFGNNI_00106 4.3e-147 yheN G deacetylase
NDOFGNNI_00107 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NDOFGNNI_00108 4.5e-231 nhaC C Na H antiporter
NDOFGNNI_00109 3.4e-84 nhaX T Belongs to the universal stress protein A family
NDOFGNNI_00110 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
NDOFGNNI_00111 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
NDOFGNNI_00112 3.7e-111 yheG GM NAD(P)H-binding
NDOFGNNI_00113 6.3e-28 sspB S spore protein
NDOFGNNI_00114 1.3e-36 yheE S Family of unknown function (DUF5342)
NDOFGNNI_00115 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
NDOFGNNI_00116 4.3e-216 yheC HJ YheC/D like ATP-grasp
NDOFGNNI_00117 2e-200 yheB S Belongs to the UPF0754 family
NDOFGNNI_00118 9.5e-48 yheA S Belongs to the UPF0342 family
NDOFGNNI_00119 2.4e-203 yhaZ L DNA alkylation repair enzyme
NDOFGNNI_00120 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
NDOFGNNI_00121 1.8e-292 hemZ H coproporphyrinogen III oxidase
NDOFGNNI_00122 2.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
NDOFGNNI_00123 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
NDOFGNNI_00125 2.1e-132 yhaR 5.3.3.18 I enoyl-CoA hydratase
NDOFGNNI_00126 1.1e-26 S YhzD-like protein
NDOFGNNI_00127 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
NDOFGNNI_00128 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
NDOFGNNI_00129 3.6e-227 yhaO L DNA repair exonuclease
NDOFGNNI_00130 0.0 yhaN L AAA domain
NDOFGNNI_00131 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
NDOFGNNI_00132 1.6e-21 yhaL S Sporulation protein YhaL
NDOFGNNI_00133 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NDOFGNNI_00134 8.7e-90 yhaK S Putative zincin peptidase
NDOFGNNI_00135 1.3e-54 yhaI S Protein of unknown function (DUF1878)
NDOFGNNI_00136 1e-113 hpr K Negative regulator of protease production and sporulation
NDOFGNNI_00137 7e-39 yhaH S YtxH-like protein
NDOFGNNI_00138 5.4e-21
NDOFGNNI_00139 3.6e-80 trpP S Tryptophan transporter TrpP
NDOFGNNI_00140 1.1e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NDOFGNNI_00141 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NDOFGNNI_00142 4.6e-137 ecsA V transporter (ATP-binding protein)
NDOFGNNI_00143 1.2e-214 ecsB U ABC transporter
NDOFGNNI_00144 3.4e-113 ecsC S EcsC protein family
NDOFGNNI_00145 2.4e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NDOFGNNI_00146 6.7e-246 yhfA C membrane
NDOFGNNI_00147 7.5e-17 1.15.1.2 C Rubrerythrin
NDOFGNNI_00148 1.1e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NDOFGNNI_00149 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NDOFGNNI_00150 6.3e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NDOFGNNI_00151 3.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NDOFGNNI_00152 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NDOFGNNI_00153 1.4e-101 yhgD K Transcriptional regulator
NDOFGNNI_00154 1e-238 yhgE S YhgE Pip N-terminal domain protein
NDOFGNNI_00155 1.5e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NDOFGNNI_00156 4.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
NDOFGNNI_00157 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
NDOFGNNI_00158 3.7e-72 3.4.13.21 S ASCH
NDOFGNNI_00159 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NDOFGNNI_00160 5.2e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NDOFGNNI_00161 1.1e-189 lplJ 6.3.1.20 H Lipoate-protein ligase
NDOFGNNI_00162 1.3e-111 yhfK GM NmrA-like family
NDOFGNNI_00163 2e-299 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NDOFGNNI_00164 1.4e-63 yhfM
NDOFGNNI_00165 2.5e-239 yhfN 3.4.24.84 O Peptidase M48
NDOFGNNI_00166 4.7e-197 aprE 3.4.21.62 O Belongs to the peptidase S8 family
NDOFGNNI_00167 1.2e-76 VY92_01935 K acetyltransferase
NDOFGNNI_00168 7e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
NDOFGNNI_00169 6.2e-158 yfmC M Periplasmic binding protein
NDOFGNNI_00170 5.5e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NDOFGNNI_00171 1.4e-195 vraB 2.3.1.9 I Belongs to the thiolase family
NDOFGNNI_00172 1.8e-270 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NDOFGNNI_00173 1.1e-90 bioY S BioY family
NDOFGNNI_00174 2.8e-182 hemAT NT chemotaxis protein
NDOFGNNI_00175 5.2e-300 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
NDOFGNNI_00176 4.7e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NDOFGNNI_00177 1.3e-32 yhzC S IDEAL
NDOFGNNI_00178 4.2e-109 comK K Competence transcription factor
NDOFGNNI_00179 1.8e-167 IQ Enoyl-(Acyl carrier protein) reductase
NDOFGNNI_00180 8.1e-39 yhjA S Excalibur calcium-binding domain
NDOFGNNI_00181 1.4e-265 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NDOFGNNI_00182 2e-26 yhjC S Protein of unknown function (DUF3311)
NDOFGNNI_00183 6.7e-60 yhjD
NDOFGNNI_00184 9.1e-110 yhjE S SNARE associated Golgi protein
NDOFGNNI_00185 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
NDOFGNNI_00186 3.4e-280 yhjG CH FAD binding domain
NDOFGNNI_00187 1.7e-93 yhjH K helix_turn_helix multiple antibiotic resistance protein
NDOFGNNI_00188 2.9e-213 glcP G Major Facilitator Superfamily
NDOFGNNI_00189 3.3e-197 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
NDOFGNNI_00190 5.8e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
NDOFGNNI_00191 1.8e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
NDOFGNNI_00192 2.2e-187 yhjM 5.1.1.1 K Transcriptional regulator
NDOFGNNI_00193 2.7e-200 abrB S membrane
NDOFGNNI_00194 1.1e-212 EGP Transmembrane secretion effector
NDOFGNNI_00195 0.0 S Sugar transport-related sRNA regulator N-term
NDOFGNNI_00196 2.2e-78 yhjR S Rubrerythrin
NDOFGNNI_00197 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
NDOFGNNI_00198 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NDOFGNNI_00199 1.2e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NDOFGNNI_00200 0.0 sbcC L COG0419 ATPase involved in DNA repair
NDOFGNNI_00201 1.1e-49 yisB V COG1403 Restriction endonuclease
NDOFGNNI_00202 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
NDOFGNNI_00203 3e-66 gerPE S Spore germination protein GerPE
NDOFGNNI_00204 6.3e-24 gerPD S Spore germination protein
NDOFGNNI_00205 5.3e-54 gerPC S Spore germination protein
NDOFGNNI_00206 4e-34 gerPB S cell differentiation
NDOFGNNI_00207 1.9e-33 gerPA S Spore germination protein
NDOFGNNI_00208 1.5e-22 yisI S Spo0E like sporulation regulatory protein
NDOFGNNI_00209 1.2e-171 cotH M Spore Coat
NDOFGNNI_00210 7.1e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NDOFGNNI_00211 3.9e-57 yisL S UPF0344 protein
NDOFGNNI_00212 0.0 wprA O Belongs to the peptidase S8 family
NDOFGNNI_00213 3.6e-102 yisN S Protein of unknown function (DUF2777)
NDOFGNNI_00214 0.0 asnO 6.3.5.4 E Asparagine synthase
NDOFGNNI_00215 1.3e-148 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
NDOFGNNI_00216 8.9e-243 yisQ V Mate efflux family protein
NDOFGNNI_00217 1.2e-160 yisR K Transcriptional regulator
NDOFGNNI_00218 2e-183 purR K helix_turn _helix lactose operon repressor
NDOFGNNI_00219 1.6e-191 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
NDOFGNNI_00220 1.8e-92 yisT S DinB family
NDOFGNNI_00221 5.4e-99 argO S Lysine exporter protein LysE YggA
NDOFGNNI_00222 6.2e-271 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NDOFGNNI_00223 2e-35 mcbG S Pentapeptide repeats (9 copies)
NDOFGNNI_00224 3.5e-154 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NDOFGNNI_00225 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
NDOFGNNI_00226 1.1e-230 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NDOFGNNI_00227 2.1e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NDOFGNNI_00228 2.8e-120 comB 3.1.3.71 H Belongs to the ComB family
NDOFGNNI_00229 7.1e-141 yitD 4.4.1.19 S synthase
NDOFGNNI_00230 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NDOFGNNI_00231 7e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NDOFGNNI_00232 1.5e-228 yitG EGP Major facilitator Superfamily
NDOFGNNI_00233 1.1e-153 yitH K Acetyltransferase (GNAT) domain
NDOFGNNI_00234 1e-70 yjcF S Acetyltransferase (GNAT) domain
NDOFGNNI_00235 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NDOFGNNI_00236 4.3e-54 yajQ S Belongs to the UPF0234 family
NDOFGNNI_00237 3.4e-160 cvfB S protein conserved in bacteria
NDOFGNNI_00238 8.5e-94
NDOFGNNI_00239 1.8e-170
NDOFGNNI_00240 7.6e-97 S Sporulation delaying protein SdpA
NDOFGNNI_00241 1.5e-58 K Transcriptional regulator PadR-like family
NDOFGNNI_00242 3.8e-94
NDOFGNNI_00243 1.4e-44 yitR S Domain of unknown function (DUF3784)
NDOFGNNI_00244 3.4e-310 nprB 3.4.24.28 E Peptidase M4
NDOFGNNI_00245 8.4e-159 yitS S protein conserved in bacteria
NDOFGNNI_00246 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
NDOFGNNI_00247 1.4e-72 ipi S Intracellular proteinase inhibitor
NDOFGNNI_00248 1.2e-17 S Protein of unknown function (DUF3813)
NDOFGNNI_00250 6e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
NDOFGNNI_00251 2.2e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
NDOFGNNI_00252 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
NDOFGNNI_00253 1.5e-22 pilT S Proteolipid membrane potential modulator
NDOFGNNI_00254 2.9e-268 yitY C D-arabinono-1,4-lactone oxidase
NDOFGNNI_00255 1.7e-88 norB G Major Facilitator Superfamily
NDOFGNNI_00256 3.6e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NDOFGNNI_00257 2.2e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NDOFGNNI_00258 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NDOFGNNI_00259 1.6e-216 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
NDOFGNNI_00260 9.7e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NDOFGNNI_00261 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
NDOFGNNI_00262 8.6e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NDOFGNNI_00263 9.5e-28 yjzC S YjzC-like protein
NDOFGNNI_00264 2.3e-16 yjzD S Protein of unknown function (DUF2929)
NDOFGNNI_00265 6.2e-142 yjaU I carboxylic ester hydrolase activity
NDOFGNNI_00266 5.8e-100 yjaV
NDOFGNNI_00267 1.6e-182 med S Transcriptional activator protein med
NDOFGNNI_00268 7.3e-26 comZ S ComZ
NDOFGNNI_00269 3.9e-10 yjzB
NDOFGNNI_00270 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NDOFGNNI_00271 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NDOFGNNI_00272 2.1e-148 yjaZ O Zn-dependent protease
NDOFGNNI_00273 5.1e-184 appD P Belongs to the ABC transporter superfamily
NDOFGNNI_00274 4.2e-186 appF E Belongs to the ABC transporter superfamily
NDOFGNNI_00275 2.4e-287 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
NDOFGNNI_00276 7.7e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NDOFGNNI_00277 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NDOFGNNI_00278 5e-147 yjbA S Belongs to the UPF0736 family
NDOFGNNI_00279 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NDOFGNNI_00280 0.0 oppA E ABC transporter substrate-binding protein
NDOFGNNI_00281 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NDOFGNNI_00282 1e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NDOFGNNI_00283 3.4e-197 oppD P Belongs to the ABC transporter superfamily
NDOFGNNI_00284 5.5e-172 oppF E Belongs to the ABC transporter superfamily
NDOFGNNI_00285 1.8e-210 yjbB EGP Major Facilitator Superfamily
NDOFGNNI_00286 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NDOFGNNI_00287 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NDOFGNNI_00288 6e-112 yjbE P Integral membrane protein TerC family
NDOFGNNI_00289 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NDOFGNNI_00290 2.3e-223 yjbF S Competence protein
NDOFGNNI_00291 0.0 pepF E oligoendopeptidase F
NDOFGNNI_00292 1.8e-20
NDOFGNNI_00294 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NDOFGNNI_00295 3.7e-72 yjbI S Bacterial-like globin
NDOFGNNI_00296 1.5e-87 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NDOFGNNI_00297 2.4e-101 yjbK S protein conserved in bacteria
NDOFGNNI_00298 7.1e-62 yjbL S Belongs to the UPF0738 family
NDOFGNNI_00299 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
NDOFGNNI_00300 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NDOFGNNI_00301 1.2e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NDOFGNNI_00302 5.1e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NDOFGNNI_00303 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NDOFGNNI_00304 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NDOFGNNI_00305 4.9e-108 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
NDOFGNNI_00306 8.8e-217 thiO 1.4.3.19 E Glycine oxidase
NDOFGNNI_00307 2.6e-29 thiS H thiamine diphosphate biosynthetic process
NDOFGNNI_00308 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NDOFGNNI_00309 5.1e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NDOFGNNI_00310 2.2e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NDOFGNNI_00311 9.5e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NDOFGNNI_00312 5.9e-54 yjbX S Spore coat protein
NDOFGNNI_00313 4.4e-82 cotZ S Spore coat protein
NDOFGNNI_00314 7.6e-96 cotY S Spore coat protein Z
NDOFGNNI_00315 1.6e-72 cotX S Spore Coat Protein X and V domain
NDOFGNNI_00316 8.8e-24 cotW
NDOFGNNI_00317 1.1e-54 cotV S Spore Coat Protein X and V domain
NDOFGNNI_00318 4.3e-56 yjcA S Protein of unknown function (DUF1360)
NDOFGNNI_00321 2.9e-38 spoVIF S Stage VI sporulation protein F
NDOFGNNI_00322 0.0 yjcD 3.6.4.12 L DNA helicase
NDOFGNNI_00323 1.7e-38
NDOFGNNI_00324 6.6e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NDOFGNNI_00325 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
NDOFGNNI_00326 2.6e-137 yjcH P COG2382 Enterochelin esterase and related enzymes
NDOFGNNI_00327 3.2e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NDOFGNNI_00328 4.2e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NDOFGNNI_00329 7.7e-97 rimJ 2.3.1.128 J Alanine acetyltransferase
NDOFGNNI_00330 5.4e-212 yjcL S Protein of unknown function (DUF819)
NDOFGNNI_00333 2.1e-190 S Putative amidase domain
NDOFGNNI_00334 2.6e-44 yjcN
NDOFGNNI_00337 8.5e-81 L Transposase
NDOFGNNI_00338 1.6e-72 yjcP
NDOFGNNI_00339 4.1e-49 S YjcQ protein
NDOFGNNI_00340 7.2e-92 yqaS L DNA packaging
NDOFGNNI_00341 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
NDOFGNNI_00342 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
NDOFGNNI_00344 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
NDOFGNNI_00345 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
NDOFGNNI_00346 2.8e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
NDOFGNNI_00347 4.1e-50 yjdF S Protein of unknown function (DUF2992)
NDOFGNNI_00348 9e-92 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
NDOFGNNI_00350 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NDOFGNNI_00351 4.2e-29 S Domain of unknown function (DUF4177)
NDOFGNNI_00352 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
NDOFGNNI_00353 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NDOFGNNI_00355 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
NDOFGNNI_00356 5.5e-83 S Protein of unknown function (DUF2690)
NDOFGNNI_00357 2.3e-20 yjfB S Putative motility protein
NDOFGNNI_00358 1.6e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
NDOFGNNI_00359 1.2e-45 T PhoQ Sensor
NDOFGNNI_00360 2e-103 yjgB S Domain of unknown function (DUF4309)
NDOFGNNI_00361 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NDOFGNNI_00362 4.3e-95 yjgD S Protein of unknown function (DUF1641)
NDOFGNNI_00363 1.1e-06 S Domain of unknown function (DUF4352)
NDOFGNNI_00364 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
NDOFGNNI_00366 3.8e-226 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
NDOFGNNI_00367 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NDOFGNNI_00368 8.2e-30
NDOFGNNI_00369 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NDOFGNNI_00370 1.9e-122 ybbM S transport system, permease component
NDOFGNNI_00371 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
NDOFGNNI_00372 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
NDOFGNNI_00373 2.8e-93 yjlB S Cupin domain
NDOFGNNI_00374 7.1e-66 yjlC S Protein of unknown function (DUF1641)
NDOFGNNI_00375 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
NDOFGNNI_00376 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
NDOFGNNI_00377 5.8e-250 yjmB G symporter YjmB
NDOFGNNI_00378 2.8e-193 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
NDOFGNNI_00379 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
NDOFGNNI_00380 4.7e-215 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
NDOFGNNI_00381 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NDOFGNNI_00382 3.7e-227 exuT G Sugar (and other) transporter
NDOFGNNI_00383 2.3e-184 exuR K transcriptional
NDOFGNNI_00384 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
NDOFGNNI_00385 4.6e-285 uxaA 4.2.1.7, 4.4.1.24 G Altronate
NDOFGNNI_00386 7.4e-130 MA20_18170 S membrane transporter protein
NDOFGNNI_00387 2.3e-78 yjoA S DinB family
NDOFGNNI_00388 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
NDOFGNNI_00389 1e-212 S response regulator aspartate phosphatase
NDOFGNNI_00391 6.3e-41 S YCII-related domain
NDOFGNNI_00392 2.9e-168 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
NDOFGNNI_00393 1.8e-60 yjqA S Bacterial PH domain
NDOFGNNI_00394 2.1e-111 yjqB S Pfam:DUF867
NDOFGNNI_00395 4.4e-160 ydbD P Catalase
NDOFGNNI_00396 4.3e-109 xkdA E IrrE N-terminal-like domain
NDOFGNNI_00397 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
NDOFGNNI_00399 5e-156 xkdB K sequence-specific DNA binding
NDOFGNNI_00400 9.2e-118 xkdC L Bacterial dnaA protein
NDOFGNNI_00403 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
NDOFGNNI_00404 5e-82 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NDOFGNNI_00405 4.1e-139 xtmA L phage terminase small subunit
NDOFGNNI_00406 1.3e-251 xtmB S phage terminase, large subunit
NDOFGNNI_00407 1.6e-285 yqbA S portal protein
NDOFGNNI_00408 3.5e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
NDOFGNNI_00409 1.3e-168 xkdG S Phage capsid family
NDOFGNNI_00410 5.5e-65 yqbG S Protein of unknown function (DUF3199)
NDOFGNNI_00411 8.7e-65 yqbH S Domain of unknown function (DUF3599)
NDOFGNNI_00412 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
NDOFGNNI_00413 1.9e-77 xkdJ
NDOFGNNI_00414 2.5e-256 xkdK S Phage tail sheath C-terminal domain
NDOFGNNI_00415 6.1e-76 xkdM S Phage tail tube protein
NDOFGNNI_00416 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
NDOFGNNI_00417 0.0 xkdO L Transglycosylase SLT domain
NDOFGNNI_00418 3.7e-122 xkdP S Lysin motif
NDOFGNNI_00419 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
NDOFGNNI_00420 2.1e-39 xkdR S Protein of unknown function (DUF2577)
NDOFGNNI_00421 9.6e-71 xkdS S Protein of unknown function (DUF2634)
NDOFGNNI_00422 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NDOFGNNI_00423 4e-104 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
NDOFGNNI_00424 6.7e-41
NDOFGNNI_00425 0.0
NDOFGNNI_00426 2.6e-55 xkdW S XkdW protein
NDOFGNNI_00427 1.7e-23 xkdX
NDOFGNNI_00428 1.2e-154 xepA
NDOFGNNI_00429 2.8e-39 xhlA S Haemolysin XhlA
NDOFGNNI_00430 9.3e-40 xhlB S SPP1 phage holin
NDOFGNNI_00431 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NDOFGNNI_00432 6.7e-23 spoIISB S Stage II sporulation protein SB
NDOFGNNI_00433 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
NDOFGNNI_00434 5.8e-175 pit P phosphate transporter
NDOFGNNI_00435 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
NDOFGNNI_00436 9.4e-242 steT E amino acid
NDOFGNNI_00437 7.2e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
NDOFGNNI_00438 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NDOFGNNI_00439 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NDOFGNNI_00441 8.5e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NDOFGNNI_00442 3.7e-135 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
NDOFGNNI_00443 1.1e-152 dppA E D-aminopeptidase
NDOFGNNI_00444 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NDOFGNNI_00445 3.6e-174 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NDOFGNNI_00446 1.9e-186 dppD P Belongs to the ABC transporter superfamily
NDOFGNNI_00447 0.0 dppE E ABC transporter substrate-binding protein
NDOFGNNI_00449 1.2e-177 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
NDOFGNNI_00450 7.5e-200 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NDOFGNNI_00451 2.2e-165 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NDOFGNNI_00452 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
NDOFGNNI_00453 3.1e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
NDOFGNNI_00454 5.3e-161 ykgA E Amidinotransferase
NDOFGNNI_00455 1.5e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
NDOFGNNI_00456 1.1e-225 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NDOFGNNI_00457 7.2e-09
NDOFGNNI_00458 2.3e-128 ykjA S Protein of unknown function (DUF421)
NDOFGNNI_00459 9.7e-97 ykkA S Protein of unknown function (DUF664)
NDOFGNNI_00460 7.9e-28 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NDOFGNNI_00461 9.7e-61 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NDOFGNNI_00462 3.5e-55 ykkC P Multidrug resistance protein
NDOFGNNI_00463 7e-50 ykkD P Multidrug resistance protein
NDOFGNNI_00464 2.5e-169 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NDOFGNNI_00465 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NDOFGNNI_00466 8.1e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NDOFGNNI_00467 1.3e-70 ohrA O Organic hydroperoxide resistance protein
NDOFGNNI_00468 4.4e-74 ohrR K COG1846 Transcriptional regulators
NDOFGNNI_00469 4.2e-71 ohrB O Organic hydroperoxide resistance protein
NDOFGNNI_00470 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
NDOFGNNI_00471 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NDOFGNNI_00472 5e-176 isp O Belongs to the peptidase S8 family
NDOFGNNI_00473 1.8e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NDOFGNNI_00474 5.3e-136 ykoC P Cobalt transport protein
NDOFGNNI_00475 7.2e-308 P ABC transporter, ATP-binding protein
NDOFGNNI_00476 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
NDOFGNNI_00477 3.9e-110 ykoF S YKOF-related Family
NDOFGNNI_00478 2.7e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NDOFGNNI_00479 8.3e-241 ykoH 2.7.13.3 T Histidine kinase
NDOFGNNI_00480 1.5e-110 ykoI S Peptidase propeptide and YPEB domain
NDOFGNNI_00481 1.4e-84 ykoJ S Peptidase propeptide and YPEB domain
NDOFGNNI_00484 2.2e-222 mgtE P Acts as a magnesium transporter
NDOFGNNI_00485 1.4e-53 tnrA K transcriptional
NDOFGNNI_00486 1.3e-17
NDOFGNNI_00487 3.4e-25 ykoL
NDOFGNNI_00488 1.3e-81 mhqR K transcriptional
NDOFGNNI_00489 1.1e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
NDOFGNNI_00490 1.1e-98 ykoP G polysaccharide deacetylase
NDOFGNNI_00491 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
NDOFGNNI_00492 0.0 ykoS
NDOFGNNI_00493 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NDOFGNNI_00494 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
NDOFGNNI_00495 3.6e-160 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NDOFGNNI_00496 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
NDOFGNNI_00497 5.4e-110 ykoX S membrane-associated protein
NDOFGNNI_00498 8.7e-176 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NDOFGNNI_00499 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NDOFGNNI_00500 4.4e-110 rsgI S Anti-sigma factor N-terminus
NDOFGNNI_00501 1.9e-26 sspD S small acid-soluble spore protein
NDOFGNNI_00502 1.2e-123 ykrK S Domain of unknown function (DUF1836)
NDOFGNNI_00503 3.5e-155 htpX O Belongs to the peptidase M48B family
NDOFGNNI_00504 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
NDOFGNNI_00505 1.2e-10 ydfR S Protein of unknown function (DUF421)
NDOFGNNI_00506 2.2e-19 ykzE
NDOFGNNI_00507 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
NDOFGNNI_00508 0.0 kinE 2.7.13.3 T Histidine kinase
NDOFGNNI_00509 1.6e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NDOFGNNI_00511 8.2e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NDOFGNNI_00512 1.2e-227 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NDOFGNNI_00513 2.3e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NDOFGNNI_00514 1.5e-230 mtnE 2.6.1.83 E Aminotransferase
NDOFGNNI_00515 8.5e-229 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NDOFGNNI_00516 5.4e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NDOFGNNI_00517 1.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NDOFGNNI_00518 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NDOFGNNI_00519 2.2e-51 XK27_09985 S Protein of unknown function (DUF1232)
NDOFGNNI_00520 6.4e-09 S Spo0E like sporulation regulatory protein
NDOFGNNI_00521 1.4e-64 eag
NDOFGNNI_00522 6.3e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
NDOFGNNI_00523 1.3e-75 ykvE K transcriptional
NDOFGNNI_00524 2.5e-125 motB N Flagellar motor protein
NDOFGNNI_00525 1e-137 motA N flagellar motor
NDOFGNNI_00526 0.0 clpE O Belongs to the ClpA ClpB family
NDOFGNNI_00527 1.4e-179 ykvI S membrane
NDOFGNNI_00528 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NDOFGNNI_00529 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
NDOFGNNI_00530 6.4e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NDOFGNNI_00531 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NDOFGNNI_00532 3.4e-61 ykvN K Transcriptional regulator
NDOFGNNI_00533 1.2e-132 IQ Enoyl-(Acyl carrier protein) reductase
NDOFGNNI_00534 6.2e-232 ykvP 3.5.1.28 M Glycosyl transferases group 1
NDOFGNNI_00535 3.5e-35 3.5.1.104 M LysM domain
NDOFGNNI_00536 2e-161 G Glycosyl hydrolases family 18
NDOFGNNI_00537 1.4e-44 ykvR S Protein of unknown function (DUF3219)
NDOFGNNI_00538 6e-25 ykvS S protein conserved in bacteria
NDOFGNNI_00539 2.8e-28
NDOFGNNI_00540 2.7e-101 ykvT 3.5.1.28 M Cell Wall Hydrolase
NDOFGNNI_00541 2.9e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NDOFGNNI_00542 1.6e-88 stoA CO thiol-disulfide
NDOFGNNI_00543 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NDOFGNNI_00544 1.4e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NDOFGNNI_00545 1.9e-178 ykvZ 5.1.1.1 K Transcriptional regulator
NDOFGNNI_00547 7.6e-128 glcT K antiterminator
NDOFGNNI_00548 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NDOFGNNI_00549 2.1e-39 ptsH G phosphocarrier protein HPr
NDOFGNNI_00550 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NDOFGNNI_00551 7.2e-39 splA S Transcriptional regulator
NDOFGNNI_00552 3.7e-201 splB 4.1.99.14 L Spore photoproduct lyase
NDOFGNNI_00553 4.9e-128 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NDOFGNNI_00554 1.6e-261 mcpC NT chemotaxis protein
NDOFGNNI_00555 5.6e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NDOFGNNI_00556 8e-124 ykwD J protein with SCP PR1 domains
NDOFGNNI_00557 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
NDOFGNNI_00558 0.0 pilS 2.7.13.3 T Histidine kinase
NDOFGNNI_00559 1.8e-220 patA 2.6.1.1 E Aminotransferase
NDOFGNNI_00560 2.2e-15
NDOFGNNI_00561 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
NDOFGNNI_00562 1.7e-84 ykyB S YkyB-like protein
NDOFGNNI_00563 4.8e-238 ykuC EGP Major facilitator Superfamily
NDOFGNNI_00564 1.5e-86 ykuD S protein conserved in bacteria
NDOFGNNI_00565 1.6e-165 ykuE S Metallophosphoesterase
NDOFGNNI_00566 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NDOFGNNI_00567 0.0 3.2.1.132 M Putative peptidoglycan binding domain
NDOFGNNI_00569 5.2e-234 ykuI T Diguanylate phosphodiesterase
NDOFGNNI_00570 3.9e-37 ykuJ S protein conserved in bacteria
NDOFGNNI_00571 4.4e-94 ykuK S Ribonuclease H-like
NDOFGNNI_00572 3.9e-27 ykzF S Antirepressor AbbA
NDOFGNNI_00573 1.6e-76 ykuL S CBS domain
NDOFGNNI_00574 3.5e-168 ccpC K Transcriptional regulator
NDOFGNNI_00575 8.5e-84 fld C Flavodoxin domain
NDOFGNNI_00576 3e-175 ykuO
NDOFGNNI_00577 3.9e-78 fld C Flavodoxin
NDOFGNNI_00578 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NDOFGNNI_00579 2.4e-214 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NDOFGNNI_00580 9e-37 ykuS S Belongs to the UPF0180 family
NDOFGNNI_00581 8.8e-142 ykuT M Mechanosensitive ion channel
NDOFGNNI_00582 3.9e-101 ykuU O Alkyl hydroperoxide reductase
NDOFGNNI_00583 6.3e-81 ykuV CO thiol-disulfide
NDOFGNNI_00584 5.8e-95 rok K Repressor of ComK
NDOFGNNI_00585 3.2e-146 yknT
NDOFGNNI_00586 1.1e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NDOFGNNI_00587 6.5e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NDOFGNNI_00588 2.4e-245 moeA 2.10.1.1 H molybdopterin
NDOFGNNI_00589 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
NDOFGNNI_00590 2.7e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
NDOFGNNI_00591 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NDOFGNNI_00592 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
NDOFGNNI_00593 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
NDOFGNNI_00594 2.9e-117 yknW S Yip1 domain
NDOFGNNI_00595 4.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NDOFGNNI_00596 2.5e-124 macB V ABC transporter, ATP-binding protein
NDOFGNNI_00597 5.6e-209 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
NDOFGNNI_00598 3.1e-136 fruR K Transcriptional regulator
NDOFGNNI_00599 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
NDOFGNNI_00600 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NDOFGNNI_00601 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NDOFGNNI_00602 8.1e-39 ykoA
NDOFGNNI_00603 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NDOFGNNI_00604 1.5e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NDOFGNNI_00605 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
NDOFGNNI_00606 1.1e-12 S Uncharacterized protein YkpC
NDOFGNNI_00607 7.7e-183 mreB D Rod-share determining protein MreBH
NDOFGNNI_00608 1.5e-43 abrB K of stationary sporulation gene expression
NDOFGNNI_00609 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
NDOFGNNI_00610 1.6e-162 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
NDOFGNNI_00611 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
NDOFGNNI_00612 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NDOFGNNI_00613 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NDOFGNNI_00614 8.2e-31 ykzG S Belongs to the UPF0356 family
NDOFGNNI_00615 1.4e-147 ykrA S hydrolases of the HAD superfamily
NDOFGNNI_00616 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NDOFGNNI_00618 9.4e-113 recN L Putative cell-wall binding lipoprotein
NDOFGNNI_00619 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NDOFGNNI_00620 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NDOFGNNI_00621 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NDOFGNNI_00622 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NDOFGNNI_00623 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
NDOFGNNI_00624 3.5e-277 speA 4.1.1.19 E Arginine
NDOFGNNI_00625 1.6e-42 yktA S Belongs to the UPF0223 family
NDOFGNNI_00626 7.1e-118 yktB S Belongs to the UPF0637 family
NDOFGNNI_00627 7.1e-26 ykzI
NDOFGNNI_00628 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
NDOFGNNI_00629 6.9e-78 ykzC S Acetyltransferase (GNAT) family
NDOFGNNI_00630 6.5e-173 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NDOFGNNI_00631 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
NDOFGNNI_00632 0.0 ylaA
NDOFGNNI_00633 2.7e-42 ylaB
NDOFGNNI_00634 2.7e-91 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
NDOFGNNI_00635 1.2e-11 sigC S Putative zinc-finger
NDOFGNNI_00636 1.8e-38 ylaE
NDOFGNNI_00637 8.2e-22 S Family of unknown function (DUF5325)
NDOFGNNI_00638 0.0 typA T GTP-binding protein TypA
NDOFGNNI_00639 4.2e-47 ylaH S YlaH-like protein
NDOFGNNI_00640 2.5e-32 ylaI S protein conserved in bacteria
NDOFGNNI_00641 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NDOFGNNI_00642 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
NDOFGNNI_00643 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NDOFGNNI_00644 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
NDOFGNNI_00645 8.7e-44 ylaN S Belongs to the UPF0358 family
NDOFGNNI_00646 4.5e-214 ftsW D Belongs to the SEDS family
NDOFGNNI_00647 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NDOFGNNI_00648 2.6e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NDOFGNNI_00649 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NDOFGNNI_00650 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NDOFGNNI_00651 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NDOFGNNI_00652 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NDOFGNNI_00653 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NDOFGNNI_00654 3e-167 ctaG S cytochrome c oxidase
NDOFGNNI_00655 3.1e-62 ylbA S YugN-like family
NDOFGNNI_00656 2.6e-74 ylbB T COG0517 FOG CBS domain
NDOFGNNI_00657 3e-201 ylbC S protein with SCP PR1 domains
NDOFGNNI_00658 4.1e-63 ylbD S Putative coat protein
NDOFGNNI_00659 6.7e-37 ylbE S YlbE-like protein
NDOFGNNI_00660 1.8e-75 ylbF S Belongs to the UPF0342 family
NDOFGNNI_00661 3.7e-38 ylbG S UPF0298 protein
NDOFGNNI_00662 1.6e-97 rsmD 2.1.1.171 L Methyltransferase
NDOFGNNI_00663 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NDOFGNNI_00664 1.1e-220 ylbJ S Sporulation integral membrane protein YlbJ
NDOFGNNI_00665 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
NDOFGNNI_00666 6.8e-187 ylbL T Belongs to the peptidase S16 family
NDOFGNNI_00667 2.8e-235 ylbM S Belongs to the UPF0348 family
NDOFGNNI_00669 2.3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
NDOFGNNI_00670 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NDOFGNNI_00671 6.8e-75 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NDOFGNNI_00672 4e-89 ylbP K n-acetyltransferase
NDOFGNNI_00673 1.8e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NDOFGNNI_00674 7.4e-305 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NDOFGNNI_00675 2.9e-78 mraZ K Belongs to the MraZ family
NDOFGNNI_00676 6.6e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NDOFGNNI_00677 3.7e-44 ftsL D Essential cell division protein
NDOFGNNI_00678 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NDOFGNNI_00679 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
NDOFGNNI_00680 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NDOFGNNI_00681 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NDOFGNNI_00682 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NDOFGNNI_00683 5.7e-186 spoVE D Belongs to the SEDS family
NDOFGNNI_00684 4.3e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NDOFGNNI_00685 5.3e-167 murB 1.3.1.98 M cell wall formation
NDOFGNNI_00686 1.7e-137 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NDOFGNNI_00687 2.4e-103 ylxW S protein conserved in bacteria
NDOFGNNI_00688 5.1e-102 ylxX S protein conserved in bacteria
NDOFGNNI_00689 6.2e-58 sbp S small basic protein
NDOFGNNI_00690 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NDOFGNNI_00691 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NDOFGNNI_00692 0.0 bpr O COG1404 Subtilisin-like serine proteases
NDOFGNNI_00693 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NDOFGNNI_00694 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NDOFGNNI_00695 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NDOFGNNI_00696 3.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NDOFGNNI_00697 4e-253 argE 3.5.1.16 E Acetylornithine deacetylase
NDOFGNNI_00698 2.4e-37 ylmC S sporulation protein
NDOFGNNI_00699 7e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
NDOFGNNI_00700 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NDOFGNNI_00701 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NDOFGNNI_00702 1.3e-39 yggT S membrane
NDOFGNNI_00703 2.4e-136 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
NDOFGNNI_00704 2.6e-67 divIVA D Cell division initiation protein
NDOFGNNI_00705 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NDOFGNNI_00706 8.5e-63 dksA T COG1734 DnaK suppressor protein
NDOFGNNI_00707 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NDOFGNNI_00708 4.2e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NDOFGNNI_00709 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NDOFGNNI_00710 2.6e-231 pyrP F Xanthine uracil
NDOFGNNI_00711 8.5e-165 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NDOFGNNI_00712 4.6e-249 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NDOFGNNI_00713 2.5e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NDOFGNNI_00714 0.0 carB 6.3.5.5 F Belongs to the CarB family
NDOFGNNI_00715 4.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NDOFGNNI_00716 2.9e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NDOFGNNI_00717 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NDOFGNNI_00718 2.9e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NDOFGNNI_00720 3.5e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NDOFGNNI_00721 1.1e-179 cysP P phosphate transporter
NDOFGNNI_00722 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NDOFGNNI_00723 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
NDOFGNNI_00724 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NDOFGNNI_00725 2e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
NDOFGNNI_00726 4.3e-83 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
NDOFGNNI_00727 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NDOFGNNI_00728 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
NDOFGNNI_00729 2.4e-156 yloC S stress-induced protein
NDOFGNNI_00730 1.5e-40 ylzA S Belongs to the UPF0296 family
NDOFGNNI_00731 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NDOFGNNI_00732 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NDOFGNNI_00733 8.2e-224 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NDOFGNNI_00734 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NDOFGNNI_00735 6e-85 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NDOFGNNI_00736 3.8e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NDOFGNNI_00737 2.9e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NDOFGNNI_00738 4.8e-207 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NDOFGNNI_00739 2.4e-141 stp 3.1.3.16 T phosphatase
NDOFGNNI_00740 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NDOFGNNI_00741 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NDOFGNNI_00742 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NDOFGNNI_00743 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
NDOFGNNI_00744 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NDOFGNNI_00745 5.5e-59 asp S protein conserved in bacteria
NDOFGNNI_00746 2.1e-299 yloV S kinase related to dihydroxyacetone kinase
NDOFGNNI_00747 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
NDOFGNNI_00748 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
NDOFGNNI_00749 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NDOFGNNI_00750 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NDOFGNNI_00751 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NDOFGNNI_00752 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NDOFGNNI_00753 6.1e-129 IQ reductase
NDOFGNNI_00754 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NDOFGNNI_00755 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NDOFGNNI_00756 0.0 smc D Required for chromosome condensation and partitioning
NDOFGNNI_00757 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NDOFGNNI_00758 3.2e-86
NDOFGNNI_00759 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NDOFGNNI_00760 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NDOFGNNI_00761 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NDOFGNNI_00762 1.2e-36 ylqC S Belongs to the UPF0109 family
NDOFGNNI_00763 1.3e-61 ylqD S YlqD protein
NDOFGNNI_00764 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NDOFGNNI_00765 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NDOFGNNI_00766 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NDOFGNNI_00767 9.3e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NDOFGNNI_00768 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NDOFGNNI_00769 8.5e-291 ylqG
NDOFGNNI_00770 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
NDOFGNNI_00771 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NDOFGNNI_00772 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NDOFGNNI_00773 1.7e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
NDOFGNNI_00774 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NDOFGNNI_00775 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NDOFGNNI_00776 2.5e-169 xerC L tyrosine recombinase XerC
NDOFGNNI_00777 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NDOFGNNI_00778 2.2e-241 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NDOFGNNI_00779 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NDOFGNNI_00780 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NDOFGNNI_00781 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
NDOFGNNI_00782 1.9e-31 fliE N Flagellar hook-basal body
NDOFGNNI_00783 2.4e-255 fliF N The M ring may be actively involved in energy transduction
NDOFGNNI_00784 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NDOFGNNI_00785 3.7e-105 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
NDOFGNNI_00786 7.2e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NDOFGNNI_00787 3.2e-69 fliJ N Flagellar biosynthesis chaperone
NDOFGNNI_00788 1.3e-36 ylxF S MgtE intracellular N domain
NDOFGNNI_00789 1.6e-218 fliK N Flagellar hook-length control protein
NDOFGNNI_00790 1.7e-72 flgD N Flagellar basal body rod modification protein
NDOFGNNI_00791 8.2e-140 flgG N Flagellar basal body rod
NDOFGNNI_00792 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
NDOFGNNI_00793 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NDOFGNNI_00794 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NDOFGNNI_00795 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
NDOFGNNI_00796 2.7e-96 fliZ N Flagellar biosynthesis protein, FliO
NDOFGNNI_00797 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
NDOFGNNI_00798 2.2e-36 fliQ N Role in flagellar biosynthesis
NDOFGNNI_00799 1.8e-131 fliR N Flagellar biosynthetic protein FliR
NDOFGNNI_00800 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NDOFGNNI_00801 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NDOFGNNI_00802 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
NDOFGNNI_00803 6.3e-157 flhG D Belongs to the ParA family
NDOFGNNI_00804 7.5e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NDOFGNNI_00805 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
NDOFGNNI_00806 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
NDOFGNNI_00807 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NDOFGNNI_00808 4.3e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NDOFGNNI_00809 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NDOFGNNI_00810 3.1e-76 ylxL
NDOFGNNI_00811 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
NDOFGNNI_00812 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NDOFGNNI_00813 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NDOFGNNI_00814 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NDOFGNNI_00815 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NDOFGNNI_00816 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
NDOFGNNI_00817 1.3e-215 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NDOFGNNI_00818 1.7e-232 rasP M zinc metalloprotease
NDOFGNNI_00819 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NDOFGNNI_00820 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NDOFGNNI_00821 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
NDOFGNNI_00822 1.1e-203 nusA K Participates in both transcription termination and antitermination
NDOFGNNI_00823 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
NDOFGNNI_00824 3.1e-47 ylxQ J ribosomal protein
NDOFGNNI_00825 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NDOFGNNI_00826 3e-44 ylxP S protein conserved in bacteria
NDOFGNNI_00827 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NDOFGNNI_00828 1.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NDOFGNNI_00829 3e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NDOFGNNI_00830 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NDOFGNNI_00831 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NDOFGNNI_00832 2.7e-182 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
NDOFGNNI_00833 4.4e-233 pepR S Belongs to the peptidase M16 family
NDOFGNNI_00834 2.6e-42 ymxH S YlmC YmxH family
NDOFGNNI_00835 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
NDOFGNNI_00836 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NDOFGNNI_00837 3.2e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NDOFGNNI_00838 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NDOFGNNI_00839 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NDOFGNNI_00840 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NDOFGNNI_00841 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
NDOFGNNI_00842 2.9e-31 S YlzJ-like protein
NDOFGNNI_00843 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NDOFGNNI_00844 1.4e-133 ymfC K Transcriptional regulator
NDOFGNNI_00845 3.4e-206 ymfD EGP Major facilitator Superfamily
NDOFGNNI_00846 2.9e-235 ymfF S Peptidase M16
NDOFGNNI_00847 1.4e-242 ymfH S zinc protease
NDOFGNNI_00848 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NDOFGNNI_00849 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
NDOFGNNI_00850 2.7e-143 ymfK S Protein of unknown function (DUF3388)
NDOFGNNI_00851 1.9e-124 ymfM S protein conserved in bacteria
NDOFGNNI_00852 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NDOFGNNI_00853 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
NDOFGNNI_00854 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NDOFGNNI_00855 1e-215 pbpX V Beta-lactamase
NDOFGNNI_00856 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
NDOFGNNI_00857 1.9e-152 ymdB S protein conserved in bacteria
NDOFGNNI_00858 1.2e-36 spoVS S Stage V sporulation protein S
NDOFGNNI_00859 7.3e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NDOFGNNI_00860 7.2e-217 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NDOFGNNI_00861 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NDOFGNNI_00862 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
NDOFGNNI_00863 2.2e-88 cotE S Spore coat protein
NDOFGNNI_00864 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NDOFGNNI_00865 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NDOFGNNI_00866 2.3e-70 S Regulatory protein YrvL
NDOFGNNI_00868 1.2e-97 ymcC S Membrane
NDOFGNNI_00869 4.4e-109 pksA K Transcriptional regulator
NDOFGNNI_00870 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
NDOFGNNI_00871 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NDOFGNNI_00872 2.4e-186 pksD Q Acyl transferase domain
NDOFGNNI_00873 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NDOFGNNI_00874 1.4e-37 acpK IQ Phosphopantetheine attachment site
NDOFGNNI_00875 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NDOFGNNI_00876 1.3e-245 pksG 2.3.3.10 I synthase
NDOFGNNI_00877 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
NDOFGNNI_00878 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
NDOFGNNI_00879 0.0 rhiB IQ polyketide synthase
NDOFGNNI_00880 0.0 pfaA Q Polyketide synthase of type I
NDOFGNNI_00881 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
NDOFGNNI_00882 0.0 dhbF IQ polyketide synthase
NDOFGNNI_00883 0.0 pks13 HQ Beta-ketoacyl synthase
NDOFGNNI_00884 2.2e-232 cypA C Cytochrome P450
NDOFGNNI_00885 2e-61 ymzB
NDOFGNNI_00886 2.8e-162 ymaE S Metallo-beta-lactamase superfamily
NDOFGNNI_00887 4.6e-252 aprX O Belongs to the peptidase S8 family
NDOFGNNI_00888 1.9e-07 K Transcriptional regulator
NDOFGNNI_00889 2.1e-126 ymaC S Replication protein
NDOFGNNI_00890 1e-78 ymaD O redox protein, regulator of disulfide bond formation
NDOFGNNI_00891 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
NDOFGNNI_00892 4.9e-51 ebrA P Small Multidrug Resistance protein
NDOFGNNI_00894 2.1e-46 ymaF S YmaF family
NDOFGNNI_00895 1.3e-173 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NDOFGNNI_00896 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NDOFGNNI_00897 3.7e-23
NDOFGNNI_00898 4.5e-22 ymzA
NDOFGNNI_00899 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
NDOFGNNI_00900 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NDOFGNNI_00901 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NDOFGNNI_00902 3.4e-109 ymaB
NDOFGNNI_00903 6.3e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NDOFGNNI_00904 1.7e-176 spoVK O stage V sporulation protein K
NDOFGNNI_00905 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NDOFGNNI_00906 7.4e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NDOFGNNI_00907 1.1e-68 glnR K transcriptional
NDOFGNNI_00908 7e-261 glnA 6.3.1.2 E glutamine synthetase
NDOFGNNI_00909 2.9e-10
NDOFGNNI_00911 8.9e-90 G SMI1-KNR4 cell-wall
NDOFGNNI_00912 4.5e-115 ynaC
NDOFGNNI_00913 1.6e-99 ynaD J Acetyltransferase (GNAT) domain
NDOFGNNI_00914 1.6e-75 S CAAX protease self-immunity
NDOFGNNI_00916 5.5e-20 K Cro/C1-type HTH DNA-binding domain
NDOFGNNI_00917 3.5e-109 ynaE S Domain of unknown function (DUF3885)
NDOFGNNI_00920 2.7e-82 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
NDOFGNNI_00921 3.9e-254 xynT G MFS/sugar transport protein
NDOFGNNI_00922 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
NDOFGNNI_00923 2.8e-213 xylR GK ROK family
NDOFGNNI_00924 6.4e-262 xylA 5.3.1.5 G Belongs to the xylose isomerase family
NDOFGNNI_00925 2.5e-291 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
NDOFGNNI_00926 1.3e-111 yokF 3.1.31.1 L RNA catabolic process
NDOFGNNI_00927 7.5e-253 iolT EGP Major facilitator Superfamily
NDOFGNNI_00928 1e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NDOFGNNI_00929 2e-82 yncE S Protein of unknown function (DUF2691)
NDOFGNNI_00930 1.9e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
NDOFGNNI_00931 5.2e-15
NDOFGNNI_00934 9.5e-163 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NDOFGNNI_00936 1.3e-134 S Domain of unknown function, YrpD
NDOFGNNI_00939 7.9e-25 tatA U protein secretion
NDOFGNNI_00940 1.8e-71
NDOFGNNI_00941 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
NDOFGNNI_00944 1.5e-256 gerAA EG Spore germination protein
NDOFGNNI_00945 4.5e-197 gerAB U Spore germination
NDOFGNNI_00946 4.2e-220 gerLC S Spore germination protein
NDOFGNNI_00947 7.7e-154 yndG S DoxX-like family
NDOFGNNI_00948 2.6e-117 yndH S Domain of unknown function (DUF4166)
NDOFGNNI_00949 0.0 yndJ S YndJ-like protein
NDOFGNNI_00951 8.6e-139 yndL S Replication protein
NDOFGNNI_00952 5.8e-74 yndM S Protein of unknown function (DUF2512)
NDOFGNNI_00953 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NDOFGNNI_00955 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NDOFGNNI_00956 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NDOFGNNI_00957 6.6e-111 yneB L resolvase
NDOFGNNI_00958 1.3e-32 ynzC S UPF0291 protein
NDOFGNNI_00959 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NDOFGNNI_00960 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
NDOFGNNI_00961 1.8e-28 yneF S UPF0154 protein
NDOFGNNI_00962 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
NDOFGNNI_00963 2.1e-126 ccdA O cytochrome c biogenesis protein
NDOFGNNI_00964 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
NDOFGNNI_00965 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
NDOFGNNI_00966 7.2e-74 yneK S Protein of unknown function (DUF2621)
NDOFGNNI_00967 5.9e-64 hspX O Spore coat protein
NDOFGNNI_00968 3.9e-19 sspP S Belongs to the SspP family
NDOFGNNI_00969 2.5e-14 sspO S Belongs to the SspO family
NDOFGNNI_00970 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NDOFGNNI_00971 1e-90 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NDOFGNNI_00973 3.1e-08 sspN S Small acid-soluble spore protein N family
NDOFGNNI_00974 3.9e-35 tlp S Belongs to the Tlp family
NDOFGNNI_00975 1.6e-73 yneP S Thioesterase-like superfamily
NDOFGNNI_00976 6.4e-53 yneQ
NDOFGNNI_00977 4.1e-49 yneR S Belongs to the HesB IscA family
NDOFGNNI_00978 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NDOFGNNI_00979 5.6e-68 yccU S CoA-binding protein
NDOFGNNI_00980 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NDOFGNNI_00981 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NDOFGNNI_00982 2.3e-12
NDOFGNNI_00983 1.3e-57 ynfC
NDOFGNNI_00984 8.2e-252 agcS E Sodium alanine symporter
NDOFGNNI_00985 2.4e-297 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
NDOFGNNI_00987 9.1e-250 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
NDOFGNNI_00988 2.3e-295 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
NDOFGNNI_00989 1.6e-79 yngA S membrane
NDOFGNNI_00990 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NDOFGNNI_00991 5.5e-104 yngC S membrane-associated protein
NDOFGNNI_00992 4.7e-232 nrnB S phosphohydrolase (DHH superfamily)
NDOFGNNI_00993 2.9e-287 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NDOFGNNI_00994 2.3e-134 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NDOFGNNI_00995 4e-167 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
NDOFGNNI_00996 1.7e-31 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
NDOFGNNI_00997 1.1e-248 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
NDOFGNNI_00998 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NDOFGNNI_00999 9.8e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
NDOFGNNI_01000 1.8e-31 S Family of unknown function (DUF5367)
NDOFGNNI_01002 2.7e-304 yngK T Glycosyl hydrolase-like 10
NDOFGNNI_01003 1.1e-63 yngL S Protein of unknown function (DUF1360)
NDOFGNNI_01004 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
NDOFGNNI_01005 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NDOFGNNI_01006 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NDOFGNNI_01007 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NDOFGNNI_01008 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NDOFGNNI_01009 2.3e-273 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
NDOFGNNI_01010 9e-189 yoxA 5.1.3.3 G Aldose 1-epimerase
NDOFGNNI_01011 2.3e-246 yoeA V MATE efflux family protein
NDOFGNNI_01012 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
NDOFGNNI_01014 2.2e-96 L Integrase
NDOFGNNI_01015 6.7e-34 yoeD G Helix-turn-helix domain
NDOFGNNI_01016 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NDOFGNNI_01017 1.5e-155 gltR1 K Transcriptional regulator
NDOFGNNI_01018 9.4e-186 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NDOFGNNI_01019 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NDOFGNNI_01020 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
NDOFGNNI_01021 7.8e-155 gltC K Transcriptional regulator
NDOFGNNI_01022 2.5e-203 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NDOFGNNI_01023 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NDOFGNNI_01024 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
NDOFGNNI_01025 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NDOFGNNI_01026 9.8e-41 yoxC S Bacterial protein of unknown function (DUF948)
NDOFGNNI_01027 1.1e-141 yoxB
NDOFGNNI_01028 1.3e-93 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NDOFGNNI_01029 1.5e-127 V ABC-2 family transporter protein
NDOFGNNI_01030 1.3e-94 V ABC-2 family transporter protein
NDOFGNNI_01031 2.8e-139 V AAA domain, putative AbiEii toxin, Type IV TA system
NDOFGNNI_01032 3e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
NDOFGNNI_01033 9.9e-233 yoaB EGP Major facilitator Superfamily
NDOFGNNI_01034 2e-280 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
NDOFGNNI_01035 6.2e-185 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NDOFGNNI_01036 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NDOFGNNI_01037 1.9e-33 yoaF
NDOFGNNI_01038 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
NDOFGNNI_01039 7e-14
NDOFGNNI_01040 1.5e-38 S Protein of unknown function (DUF4025)
NDOFGNNI_01041 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
NDOFGNNI_01042 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
NDOFGNNI_01043 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
NDOFGNNI_01044 2.3e-111 yoaK S Membrane
NDOFGNNI_01045 2.5e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
NDOFGNNI_01046 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
NDOFGNNI_01048 3.8e-234 oxdC 4.1.1.2 G Oxalate decarboxylase
NDOFGNNI_01050 1.9e-146 yoaP 3.1.3.18 K YoaP-like
NDOFGNNI_01051 2e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
NDOFGNNI_01052 4.1e-89
NDOFGNNI_01053 2.4e-172 yoaR V vancomycin resistance protein
NDOFGNNI_01054 4.3e-75 yoaS S Protein of unknown function (DUF2975)
NDOFGNNI_01055 4.2e-37 yozG K Transcriptional regulator
NDOFGNNI_01056 1.4e-147 yoaT S Protein of unknown function (DUF817)
NDOFGNNI_01057 4.3e-158 yoaU K LysR substrate binding domain
NDOFGNNI_01058 1.5e-158 yijE EG EamA-like transporter family
NDOFGNNI_01059 1.8e-77 yoaW
NDOFGNNI_01060 1.3e-116 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
NDOFGNNI_01061 5.9e-166 bla 3.5.2.6 V beta-lactamase
NDOFGNNI_01065 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
NDOFGNNI_01066 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
NDOFGNNI_01067 1.4e-37 S TM2 domain
NDOFGNNI_01068 5.7e-58 K Helix-turn-helix
NDOFGNNI_01070 1.6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
NDOFGNNI_01071 6.6e-127 yoqW S Belongs to the SOS response-associated peptidase family
NDOFGNNI_01072 1.8e-178 yobF
NDOFGNNI_01077 1.7e-207 S aspartate phosphatase
NDOFGNNI_01079 1.2e-123 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NDOFGNNI_01080 1.4e-59 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NDOFGNNI_01081 2.6e-38 S YolD-like protein
NDOFGNNI_01082 1.2e-49
NDOFGNNI_01083 0.0 K Psort location Cytoplasmic, score
NDOFGNNI_01084 2.7e-157 yobJ
NDOFGNNI_01085 3e-86 S SMI1-KNR4 cell-wall
NDOFGNNI_01086 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NDOFGNNI_01087 7.9e-105 yokH G SMI1 / KNR4 family
NDOFGNNI_01088 9.5e-280 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
NDOFGNNI_01089 0.0 yobO M Pectate lyase superfamily protein
NDOFGNNI_01090 9.9e-55 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
NDOFGNNI_01091 1e-136 yobQ K helix_turn_helix, arabinose operon control protein
NDOFGNNI_01092 2.5e-143 yobR 2.3.1.1 J FR47-like protein
NDOFGNNI_01093 3e-99 yobS K Transcriptional regulator
NDOFGNNI_01094 4.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
NDOFGNNI_01095 1.5e-88 yobU K Bacterial transcription activator, effector binding domain
NDOFGNNI_01096 9e-178 yobV K WYL domain
NDOFGNNI_01097 3.2e-95 yobW
NDOFGNNI_01098 1e-51 czrA K transcriptional
NDOFGNNI_01099 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NDOFGNNI_01100 1.5e-92 yozB S membrane
NDOFGNNI_01101 2.2e-145
NDOFGNNI_01102 1.9e-94 yocC
NDOFGNNI_01103 6.9e-189 yocD 3.4.17.13 V peptidase S66
NDOFGNNI_01104 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NDOFGNNI_01105 3.2e-198 desK 2.7.13.3 T Histidine kinase
NDOFGNNI_01106 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NDOFGNNI_01107 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
NDOFGNNI_01108 0.0 recQ 3.6.4.12 L DNA helicase
NDOFGNNI_01109 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NDOFGNNI_01110 3.3e-83 dksA T general stress protein
NDOFGNNI_01111 6.4e-54 yocL
NDOFGNNI_01112 6.6e-34
NDOFGNNI_01113 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
NDOFGNNI_01114 1.1e-40 yozN
NDOFGNNI_01115 1.9e-36 yocN
NDOFGNNI_01116 4.2e-56 yozO S Bacterial PH domain
NDOFGNNI_01117 2.7e-31 yozC
NDOFGNNI_01118 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
NDOFGNNI_01119 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
NDOFGNNI_01120 1.3e-164 sodA 1.15.1.1 P Superoxide dismutase
NDOFGNNI_01121 9.9e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NDOFGNNI_01122 8.6e-168 yocS S -transporter
NDOFGNNI_01123 3.5e-193 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NDOFGNNI_01124 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NDOFGNNI_01125 0.0 yojO P Von Willebrand factor
NDOFGNNI_01126 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
NDOFGNNI_01127 1.5e-109 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NDOFGNNI_01128 4.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NDOFGNNI_01129 4.1e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
NDOFGNNI_01130 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NDOFGNNI_01132 4.2e-245 norM V Multidrug efflux pump
NDOFGNNI_01133 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NDOFGNNI_01134 2.1e-125 yojG S deacetylase
NDOFGNNI_01135 2.2e-60 yojF S Protein of unknown function (DUF1806)
NDOFGNNI_01136 1.5e-43
NDOFGNNI_01137 6.6e-162 rarD S -transporter
NDOFGNNI_01138 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
NDOFGNNI_01139 3.4e-09
NDOFGNNI_01140 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
NDOFGNNI_01141 3.8e-66 yodA S tautomerase
NDOFGNNI_01142 1.7e-57 yodB K transcriptional
NDOFGNNI_01143 4.8e-108 yodC C nitroreductase
NDOFGNNI_01144 3.8e-113 mhqD S Carboxylesterase
NDOFGNNI_01145 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
NDOFGNNI_01146 6.2e-28 S Protein of unknown function (DUF3311)
NDOFGNNI_01147 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NDOFGNNI_01148 1.9e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
NDOFGNNI_01149 1.7e-128 yodH Q Methyltransferase
NDOFGNNI_01150 5.2e-24 yodI
NDOFGNNI_01151 2.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NDOFGNNI_01152 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
NDOFGNNI_01153 5.3e-09
NDOFGNNI_01154 3.6e-54 yodL S YodL-like
NDOFGNNI_01155 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
NDOFGNNI_01156 2.8e-24 yozD S YozD-like protein
NDOFGNNI_01158 1.4e-124 yodN
NDOFGNNI_01159 1.4e-36 yozE S Belongs to the UPF0346 family
NDOFGNNI_01160 2.9e-47 yokU S YokU-like protein, putative antitoxin
NDOFGNNI_01161 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
NDOFGNNI_01162 9.4e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
NDOFGNNI_01163 4.2e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
NDOFGNNI_01164 8e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NDOFGNNI_01165 1.7e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NDOFGNNI_01166 4e-248 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NDOFGNNI_01168 2.9e-145 yiiD K acetyltransferase
NDOFGNNI_01169 1e-256 cgeD M maturation of the outermost layer of the spore
NDOFGNNI_01170 3.5e-38 cgeC
NDOFGNNI_01171 1.2e-65 cgeA
NDOFGNNI_01172 3.3e-188 cgeB S Spore maturation protein
NDOFGNNI_01173 3.6e-213 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
NDOFGNNI_01174 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
NDOFGNNI_01175 1.4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NDOFGNNI_01176 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NDOFGNNI_01177 1.6e-70 ypoP K transcriptional
NDOFGNNI_01178 2.6e-223 mepA V MATE efflux family protein
NDOFGNNI_01179 5.5e-29 ypmT S Uncharacterized ympT
NDOFGNNI_01180 1.1e-98 ypmS S protein conserved in bacteria
NDOFGNNI_01181 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
NDOFGNNI_01182 1.2e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NDOFGNNI_01183 3.1e-40 ypmP S Protein of unknown function (DUF2535)
NDOFGNNI_01184 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NDOFGNNI_01185 6.1e-185 pspF K Transcriptional regulator
NDOFGNNI_01186 4.2e-110 hlyIII S protein, Hemolysin III
NDOFGNNI_01187 7.4e-112 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NDOFGNNI_01188 6.7e-95 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NDOFGNNI_01189 5.3e-155 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NDOFGNNI_01190 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NDOFGNNI_01191 8.6e-113 ypjP S YpjP-like protein
NDOFGNNI_01192 1.6e-143 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
NDOFGNNI_01193 1.7e-75 yphP S Belongs to the UPF0403 family
NDOFGNNI_01194 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NDOFGNNI_01195 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
NDOFGNNI_01196 3.1e-110 ypgQ S phosphohydrolase
NDOFGNNI_01197 2.3e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
NDOFGNNI_01198 4.7e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NDOFGNNI_01199 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NDOFGNNI_01200 7.9e-31 cspD K Cold-shock protein
NDOFGNNI_01201 3.8e-16 degR
NDOFGNNI_01202 8.1e-31 S Protein of unknown function (DUF2564)
NDOFGNNI_01203 3e-29 ypeQ S Zinc-finger
NDOFGNNI_01204 8.9e-127 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
NDOFGNNI_01205 5.4e-107 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NDOFGNNI_01206 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
NDOFGNNI_01208 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
NDOFGNNI_01209 2e-07
NDOFGNNI_01210 1e-38 ypbS S Protein of unknown function (DUF2533)
NDOFGNNI_01211 0.0 ypbR S Dynamin family
NDOFGNNI_01212 5.1e-87 ypbQ S protein conserved in bacteria
NDOFGNNI_01213 4.4e-208 bcsA Q Naringenin-chalcone synthase
NDOFGNNI_01214 1.6e-228 pbuX F xanthine
NDOFGNNI_01215 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NDOFGNNI_01216 9.3e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NDOFGNNI_01217 2.5e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
NDOFGNNI_01218 7e-104 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
NDOFGNNI_01219 2.9e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
NDOFGNNI_01220 3.9e-187 ptxS K transcriptional
NDOFGNNI_01221 1.7e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NDOFGNNI_01222 7.1e-133 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NDOFGNNI_01223 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
NDOFGNNI_01225 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NDOFGNNI_01226 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NDOFGNNI_01227 3.3e-92 ypsA S Belongs to the UPF0398 family
NDOFGNNI_01228 1.3e-237 yprB L RNase_H superfamily
NDOFGNNI_01229 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NDOFGNNI_01230 1.9e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
NDOFGNNI_01231 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
NDOFGNNI_01232 1.2e-48 yppG S YppG-like protein
NDOFGNNI_01234 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
NDOFGNNI_01237 2.6e-188 yppC S Protein of unknown function (DUF2515)
NDOFGNNI_01238 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NDOFGNNI_01239 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
NDOFGNNI_01240 4.7e-93 ypoC
NDOFGNNI_01241 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NDOFGNNI_01242 5.7e-129 dnaD L DNA replication protein DnaD
NDOFGNNI_01243 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
NDOFGNNI_01244 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NDOFGNNI_01245 3.4e-80 ypmB S protein conserved in bacteria
NDOFGNNI_01246 6.7e-23 ypmA S Protein of unknown function (DUF4264)
NDOFGNNI_01247 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NDOFGNNI_01248 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NDOFGNNI_01249 4.7e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NDOFGNNI_01250 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NDOFGNNI_01251 2.5e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NDOFGNNI_01252 7e-220 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NDOFGNNI_01253 6.9e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
NDOFGNNI_01254 2.4e-127 bshB1 S proteins, LmbE homologs
NDOFGNNI_01255 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
NDOFGNNI_01256 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NDOFGNNI_01257 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
NDOFGNNI_01258 2.4e-156 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
NDOFGNNI_01259 1e-142 ypjB S sporulation protein
NDOFGNNI_01260 5.8e-98 ypjA S membrane
NDOFGNNI_01261 4.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
NDOFGNNI_01262 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
NDOFGNNI_01263 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
NDOFGNNI_01264 4.2e-77 ypiF S Protein of unknown function (DUF2487)
NDOFGNNI_01265 1.1e-98 ypiB S Belongs to the UPF0302 family
NDOFGNNI_01266 5.9e-233 S COG0457 FOG TPR repeat
NDOFGNNI_01267 9.9e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NDOFGNNI_01268 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NDOFGNNI_01269 2.1e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NDOFGNNI_01270 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NDOFGNNI_01271 1.5e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NDOFGNNI_01272 5.7e-115 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
NDOFGNNI_01273 1.2e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NDOFGNNI_01274 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NDOFGNNI_01275 2.8e-293 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NDOFGNNI_01276 3e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NDOFGNNI_01277 5.8e-205 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NDOFGNNI_01278 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NDOFGNNI_01279 1.1e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
NDOFGNNI_01280 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NDOFGNNI_01281 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NDOFGNNI_01282 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NDOFGNNI_01283 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NDOFGNNI_01284 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NDOFGNNI_01285 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
NDOFGNNI_01286 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NDOFGNNI_01287 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NDOFGNNI_01288 6e-137 yphF
NDOFGNNI_01289 1.6e-18 yphE S Protein of unknown function (DUF2768)
NDOFGNNI_01290 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NDOFGNNI_01291 6.7e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NDOFGNNI_01292 7.9e-28 ypzH
NDOFGNNI_01293 2.5e-161 seaA S YIEGIA protein
NDOFGNNI_01294 1.3e-102 yphA
NDOFGNNI_01295 1.4e-07 S YpzI-like protein
NDOFGNNI_01296 5.9e-186 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NDOFGNNI_01297 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
NDOFGNNI_01298 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NDOFGNNI_01299 4.1e-23 S Family of unknown function (DUF5359)
NDOFGNNI_01300 3.9e-111 ypfA M Flagellar protein YcgR
NDOFGNNI_01301 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
NDOFGNNI_01302 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
NDOFGNNI_01303 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
NDOFGNNI_01304 7.4e-175 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
NDOFGNNI_01305 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NDOFGNNI_01306 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NDOFGNNI_01307 2.6e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
NDOFGNNI_01308 2.8e-81 ypbF S Protein of unknown function (DUF2663)
NDOFGNNI_01309 1.7e-78 ypbE M Lysin motif
NDOFGNNI_01310 2.2e-100 ypbD S metal-dependent membrane protease
NDOFGNNI_01311 9.2e-286 recQ 3.6.4.12 L DNA helicase
NDOFGNNI_01312 2.6e-197 ypbB 5.1.3.1 S protein conserved in bacteria
NDOFGNNI_01313 4.7e-41 fer C Ferredoxin
NDOFGNNI_01314 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NDOFGNNI_01315 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NDOFGNNI_01316 6.1e-132 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NDOFGNNI_01317 3.5e-197 rsiX
NDOFGNNI_01318 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
NDOFGNNI_01319 0.0 resE 2.7.13.3 T Histidine kinase
NDOFGNNI_01320 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NDOFGNNI_01321 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NDOFGNNI_01322 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
NDOFGNNI_01323 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NDOFGNNI_01324 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NDOFGNNI_01325 1.9e-87 spmB S Spore maturation protein
NDOFGNNI_01326 3.5e-103 spmA S Spore maturation protein
NDOFGNNI_01327 4.7e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
NDOFGNNI_01328 4e-98 ypuI S Protein of unknown function (DUF3907)
NDOFGNNI_01329 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NDOFGNNI_01330 4.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NDOFGNNI_01331 1.7e-93 ypuF S Domain of unknown function (DUF309)
NDOFGNNI_01332 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NDOFGNNI_01333 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NDOFGNNI_01334 9.8e-230 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NDOFGNNI_01335 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
NDOFGNNI_01336 4.9e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NDOFGNNI_01337 7.8e-55 ypuD
NDOFGNNI_01338 6.2e-94 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NDOFGNNI_01339 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
NDOFGNNI_01342 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NDOFGNNI_01343 8.1e-149 ypuA S Secreted protein
NDOFGNNI_01344 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NDOFGNNI_01345 1.4e-273 spoVAF EG Stage V sporulation protein AF
NDOFGNNI_01346 1.4e-110 spoVAEA S stage V sporulation protein
NDOFGNNI_01347 2.2e-57 spoVAEB S stage V sporulation protein
NDOFGNNI_01348 9e-192 spoVAD I Stage V sporulation protein AD
NDOFGNNI_01349 2.3e-78 spoVAC S stage V sporulation protein AC
NDOFGNNI_01350 1e-67 spoVAB S Stage V sporulation protein AB
NDOFGNNI_01351 7.4e-112 spoVAA S Stage V sporulation protein AA
NDOFGNNI_01352 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NDOFGNNI_01353 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NDOFGNNI_01354 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
NDOFGNNI_01355 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
NDOFGNNI_01356 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NDOFGNNI_01357 1.2e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NDOFGNNI_01358 2.6e-166 xerD L recombinase XerD
NDOFGNNI_01359 3.7e-37 S Protein of unknown function (DUF4227)
NDOFGNNI_01360 2.4e-80 fur P Belongs to the Fur family
NDOFGNNI_01361 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NDOFGNNI_01362 2.2e-31 yqkK
NDOFGNNI_01363 5.5e-242 mleA 1.1.1.38 C malic enzyme
NDOFGNNI_01364 2.7e-234 mleN C Na H antiporter
NDOFGNNI_01365 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
NDOFGNNI_01366 1.2e-183 ansA 3.5.1.1 EJ L-asparaginase
NDOFGNNI_01367 4.5e-58 ansR K Transcriptional regulator
NDOFGNNI_01368 1.4e-220 yqxK 3.6.4.12 L DNA helicase
NDOFGNNI_01369 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
NDOFGNNI_01371 4.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
NDOFGNNI_01372 3.1e-12 yqkE S Protein of unknown function (DUF3886)
NDOFGNNI_01373 8.5e-173 yqkD S COG1073 Hydrolases of the alpha beta superfamily
NDOFGNNI_01374 9.4e-39 yqkC S Protein of unknown function (DUF2552)
NDOFGNNI_01375 2.8e-54 yqkB S Belongs to the HesB IscA family
NDOFGNNI_01376 7.5e-194 yqkA K GrpB protein
NDOFGNNI_01377 2e-58 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
NDOFGNNI_01378 1.8e-86 yqjY K acetyltransferase
NDOFGNNI_01379 2.2e-49 S YolD-like protein
NDOFGNNI_01380 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NDOFGNNI_01382 6.1e-222 yqjV G Major Facilitator Superfamily
NDOFGNNI_01384 2.1e-72 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NDOFGNNI_01385 1.2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
NDOFGNNI_01386 6e-260 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
NDOFGNNI_01387 1e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
NDOFGNNI_01388 1.3e-179 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
NDOFGNNI_01389 8.6e-148 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NDOFGNNI_01390 0.0 rocB E arginine degradation protein
NDOFGNNI_01391 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NDOFGNNI_01392 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NDOFGNNI_01393 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NDOFGNNI_01394 2.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NDOFGNNI_01395 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NDOFGNNI_01396 1.6e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NDOFGNNI_01397 4.5e-24 yqzJ
NDOFGNNI_01398 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NDOFGNNI_01399 8.9e-141 yqjF S Uncharacterized conserved protein (COG2071)
NDOFGNNI_01400 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
NDOFGNNI_01401 3.8e-287 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NDOFGNNI_01402 8.7e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
NDOFGNNI_01404 1.4e-98 yqjB S protein conserved in bacteria
NDOFGNNI_01405 3.3e-175 yqjA S Putative aromatic acid exporter C-terminal domain
NDOFGNNI_01406 4.5e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NDOFGNNI_01407 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
NDOFGNNI_01408 4.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
NDOFGNNI_01409 9.3e-77 yqiW S Belongs to the UPF0403 family
NDOFGNNI_01410 8.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NDOFGNNI_01411 7.9e-208 norA EGP Major facilitator Superfamily
NDOFGNNI_01412 2.6e-152 bmrR K helix_turn_helix, mercury resistance
NDOFGNNI_01413 1.2e-225 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NDOFGNNI_01414 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NDOFGNNI_01415 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NDOFGNNI_01416 3.4e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NDOFGNNI_01417 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
NDOFGNNI_01418 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
NDOFGNNI_01419 3.9e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
NDOFGNNI_01420 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
NDOFGNNI_01421 2.6e-33 yqzF S Protein of unknown function (DUF2627)
NDOFGNNI_01422 3e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NDOFGNNI_01423 1.1e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
NDOFGNNI_01424 2.4e-209 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
NDOFGNNI_01425 1.7e-210 mmgC I acyl-CoA dehydrogenase
NDOFGNNI_01426 4.7e-157 hbdA 1.1.1.157 I Dehydrogenase
NDOFGNNI_01427 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
NDOFGNNI_01428 1.8e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NDOFGNNI_01429 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
NDOFGNNI_01430 5.9e-27
NDOFGNNI_01431 2.1e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NDOFGNNI_01433 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NDOFGNNI_01434 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
NDOFGNNI_01435 2.4e-311 recN L May be involved in recombinational repair of damaged DNA
NDOFGNNI_01436 1.7e-78 argR K Regulates arginine biosynthesis genes
NDOFGNNI_01437 3.3e-155 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
NDOFGNNI_01438 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NDOFGNNI_01439 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NDOFGNNI_01440 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NDOFGNNI_01441 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NDOFGNNI_01442 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NDOFGNNI_01443 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NDOFGNNI_01444 2.1e-67 yqhY S protein conserved in bacteria
NDOFGNNI_01445 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NDOFGNNI_01446 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NDOFGNNI_01447 9.9e-91 spoIIIAH S SpoIIIAH-like protein
NDOFGNNI_01448 1.9e-108 spoIIIAG S stage III sporulation protein AG
NDOFGNNI_01449 2.6e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
NDOFGNNI_01450 3.8e-197 spoIIIAE S stage III sporulation protein AE
NDOFGNNI_01451 2.3e-58 spoIIIAD S Stage III sporulation protein AD
NDOFGNNI_01452 7.6e-29 spoIIIAC S stage III sporulation protein AC
NDOFGNNI_01453 1.1e-84 spoIIIAB S Stage III sporulation protein
NDOFGNNI_01454 3e-170 spoIIIAA S stage III sporulation protein AA
NDOFGNNI_01455 7.9e-37 yqhV S Protein of unknown function (DUF2619)
NDOFGNNI_01456 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NDOFGNNI_01457 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NDOFGNNI_01458 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
NDOFGNNI_01459 2.3e-93 yqhR S Conserved membrane protein YqhR
NDOFGNNI_01460 8e-174 yqhQ S Protein of unknown function (DUF1385)
NDOFGNNI_01461 2.2e-61 yqhP
NDOFGNNI_01462 4e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
NDOFGNNI_01463 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NDOFGNNI_01464 2.2e-159 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NDOFGNNI_01465 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
NDOFGNNI_01466 2.6e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NDOFGNNI_01467 1.7e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NDOFGNNI_01468 3.1e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
NDOFGNNI_01469 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NDOFGNNI_01470 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
NDOFGNNI_01471 1.2e-24 sinI S Anti-repressor SinI
NDOFGNNI_01472 1e-54 sinR K transcriptional
NDOFGNNI_01473 2.3e-142 tasA S Cell division protein FtsN
NDOFGNNI_01474 6.7e-59 sipW 3.4.21.89 U Signal peptidase
NDOFGNNI_01475 2.7e-116 yqxM
NDOFGNNI_01476 7.3e-54 yqzG S Protein of unknown function (DUF3889)
NDOFGNNI_01477 1.4e-26 yqzE S YqzE-like protein
NDOFGNNI_01478 4e-44 S ComG operon protein 7
NDOFGNNI_01479 5.9e-35 comGF U Putative Competence protein ComGF
NDOFGNNI_01480 1.1e-59 comGE
NDOFGNNI_01481 7.7e-68 gspH NU protein transport across the cell outer membrane
NDOFGNNI_01482 5.2e-47 comGC U Required for transformation and DNA binding
NDOFGNNI_01483 5.1e-174 comGB NU COG1459 Type II secretory pathway, component PulF
NDOFGNNI_01484 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NDOFGNNI_01487 7.2e-175 corA P Mg2 transporter protein
NDOFGNNI_01488 1.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NDOFGNNI_01489 1.2e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NDOFGNNI_01491 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
NDOFGNNI_01492 1.8e-37 yqgY S Protein of unknown function (DUF2626)
NDOFGNNI_01493 1.9e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
NDOFGNNI_01494 8.9e-23 yqgW S Protein of unknown function (DUF2759)
NDOFGNNI_01495 6.9e-50 yqgV S Thiamine-binding protein
NDOFGNNI_01496 2.7e-199 yqgU
NDOFGNNI_01497 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
NDOFGNNI_01498 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NDOFGNNI_01499 5.2e-181 glcK 2.7.1.2 G Glucokinase
NDOFGNNI_01500 3.1e-33 yqgQ S Protein conserved in bacteria
NDOFGNNI_01501 8.9e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
NDOFGNNI_01502 2.5e-09 yqgO
NDOFGNNI_01503 2.5e-103 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NDOFGNNI_01504 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NDOFGNNI_01505 2e-197 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
NDOFGNNI_01507 9.2e-51 yqzD
NDOFGNNI_01508 7.3e-72 yqzC S YceG-like family
NDOFGNNI_01509 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NDOFGNNI_01510 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NDOFGNNI_01511 2.2e-157 pstA P Phosphate transport system permease
NDOFGNNI_01512 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
NDOFGNNI_01513 1.8e-143 pstS P Phosphate
NDOFGNNI_01514 0.0 pbpA 3.4.16.4 M penicillin-binding protein
NDOFGNNI_01515 2.5e-231 yqgE EGP Major facilitator superfamily
NDOFGNNI_01516 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
NDOFGNNI_01517 4e-73 yqgC S protein conserved in bacteria
NDOFGNNI_01518 1.1e-130 yqgB S Protein of unknown function (DUF1189)
NDOFGNNI_01519 1.5e-46 yqfZ M LysM domain
NDOFGNNI_01520 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NDOFGNNI_01521 4.3e-62 yqfX S membrane
NDOFGNNI_01522 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
NDOFGNNI_01523 1.9e-77 zur P Belongs to the Fur family
NDOFGNNI_01524 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NDOFGNNI_01525 2.1e-36 yqfT S Protein of unknown function (DUF2624)
NDOFGNNI_01526 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NDOFGNNI_01527 1.7e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NDOFGNNI_01528 2.9e-14 yqfQ S YqfQ-like protein
NDOFGNNI_01529 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NDOFGNNI_01530 2.8e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NDOFGNNI_01531 1.8e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
NDOFGNNI_01532 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
NDOFGNNI_01533 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NDOFGNNI_01534 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NDOFGNNI_01535 4.5e-88 yaiI S Belongs to the UPF0178 family
NDOFGNNI_01536 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NDOFGNNI_01537 4.5e-112 ccpN K CBS domain
NDOFGNNI_01538 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NDOFGNNI_01539 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NDOFGNNI_01540 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
NDOFGNNI_01541 8.4e-19 S YqzL-like protein
NDOFGNNI_01542 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NDOFGNNI_01543 2.1e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NDOFGNNI_01544 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NDOFGNNI_01545 2e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NDOFGNNI_01546 0.0 yqfF S membrane-associated HD superfamily hydrolase
NDOFGNNI_01548 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
NDOFGNNI_01549 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
NDOFGNNI_01550 2.7e-45 yqfC S sporulation protein YqfC
NDOFGNNI_01551 3.7e-22 yqfB
NDOFGNNI_01552 4.3e-122 yqfA S UPF0365 protein
NDOFGNNI_01553 4.5e-228 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
NDOFGNNI_01554 2.5e-61 yqeY S Yqey-like protein
NDOFGNNI_01555 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NDOFGNNI_01556 8.2e-158 yqeW P COG1283 Na phosphate symporter
NDOFGNNI_01557 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
NDOFGNNI_01558 9.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NDOFGNNI_01559 6e-174 prmA J Methylates ribosomal protein L11
NDOFGNNI_01560 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NDOFGNNI_01561 0.0 dnaK O Heat shock 70 kDa protein
NDOFGNNI_01562 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NDOFGNNI_01563 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NDOFGNNI_01564 7e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
NDOFGNNI_01565 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NDOFGNNI_01566 7.2e-53 yqxA S Protein of unknown function (DUF3679)
NDOFGNNI_01567 2e-222 spoIIP M stage II sporulation protein P
NDOFGNNI_01568 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NDOFGNNI_01569 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
NDOFGNNI_01570 5.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
NDOFGNNI_01571 4.1e-15 S YqzM-like protein
NDOFGNNI_01572 0.0 comEC S Competence protein ComEC
NDOFGNNI_01573 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
NDOFGNNI_01574 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
NDOFGNNI_01575 2.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NDOFGNNI_01576 2.9e-139 yqeM Q Methyltransferase
NDOFGNNI_01577 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NDOFGNNI_01578 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
NDOFGNNI_01579 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NDOFGNNI_01580 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
NDOFGNNI_01581 5.1e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NDOFGNNI_01582 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NDOFGNNI_01583 5.3e-95 yqeG S hydrolase of the HAD superfamily
NDOFGNNI_01585 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
NDOFGNNI_01586 1.7e-131 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NDOFGNNI_01587 2.3e-105 yqeD S SNARE associated Golgi protein
NDOFGNNI_01588 3.8e-170 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
NDOFGNNI_01589 6.7e-133 yqeB
NDOFGNNI_01590 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
NDOFGNNI_01591 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NDOFGNNI_01592 3.5e-277 cisA2 L Recombinase
NDOFGNNI_01595 1.4e-112 ydfS S Protein of unknown function (DUF421)
NDOFGNNI_01596 8.4e-149 yhjR 2.7.7.87 S Rubrerythrin
NDOFGNNI_01597 1.2e-111 yrkJ S membrane transporter protein
NDOFGNNI_01598 9.5e-33 yrkI O Belongs to the sulfur carrier protein TusA family
NDOFGNNI_01599 4.5e-200 yrkH P Rhodanese Homology Domain
NDOFGNNI_01600 1.9e-57 perX S DsrE/DsrF-like family
NDOFGNNI_01601 5.6e-87 yrkF OP Belongs to the sulfur carrier protein TusA family
NDOFGNNI_01602 8.4e-55 P Rhodanese Homology Domain
NDOFGNNI_01603 3.4e-80 yrkE O DsrE/DsrF/DrsH-like family
NDOFGNNI_01604 1.6e-36 yrkD S protein conserved in bacteria
NDOFGNNI_01605 5.1e-21
NDOFGNNI_01606 3.5e-100 yrkC G Cupin domain
NDOFGNNI_01608 5e-66 S response regulator aspartate phosphatase
NDOFGNNI_01610 4.3e-298 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NDOFGNNI_01611 7.8e-82 S SMI1-KNR4 cell-wall
NDOFGNNI_01612 3e-117 EGP Necrosis inducing protein (NPP1)
NDOFGNNI_01613 1.3e-129 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NDOFGNNI_01614 6.4e-67 S Bacteriophage holin family
NDOFGNNI_01615 3e-159 xepA
NDOFGNNI_01616 1.3e-18
NDOFGNNI_01617 7.3e-42 xkdW S XkdW protein
NDOFGNNI_01618 2.3e-164
NDOFGNNI_01619 1e-36
NDOFGNNI_01620 7.4e-98 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
NDOFGNNI_01621 1.2e-186 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NDOFGNNI_01622 1.3e-70 xkdS S Protein of unknown function (DUF2634)
NDOFGNNI_01623 9.4e-32 xkdR S Protein of unknown function (DUF2577)
NDOFGNNI_01624 1.2e-177 yqbQ 3.2.1.96 G NLP P60 protein
NDOFGNNI_01625 2.2e-42 qacC U Small Multidrug Resistance protein
NDOFGNNI_01626 2.2e-112 xkdP S Lysin motif
NDOFGNNI_01627 0.0 xkdO L Transglycosylase SLT domain
NDOFGNNI_01628 6.2e-68 S Phage XkdN-like tail assembly chaperone protein, TAC
NDOFGNNI_01629 2.3e-75 xkdM S Phage tail tube protein
NDOFGNNI_01630 2.2e-252 xkdK S Phage tail sheath C-terminal domain
NDOFGNNI_01631 1e-24
NDOFGNNI_01632 5.1e-75
NDOFGNNI_01633 5.3e-84 S Bacteriophage HK97-gp10, putative tail-component
NDOFGNNI_01634 1.7e-63 yqbH S Domain of unknown function (DUF3599)
NDOFGNNI_01635 2.7e-67 S Protein of unknown function (DUF3199)
NDOFGNNI_01636 1.2e-46 S YqbF, hypothetical protein domain
NDOFGNNI_01637 1.9e-167 xkdG S Phage capsid family
NDOFGNNI_01638 1.4e-112 yqbD 2.1.1.72 L Putative phage serine protease XkdF
NDOFGNNI_01640 1.3e-149 S Phage Mu protein F like protein
NDOFGNNI_01641 2.5e-286 yqbA S portal protein
NDOFGNNI_01642 1.4e-248 S phage terminase, large subunit
NDOFGNNI_01643 8.3e-99 yqaS L DNA packaging
NDOFGNNI_01645 2.8e-89 yrdC 3.5.1.19 Q Isochorismatase family
NDOFGNNI_01649 1.1e-48 wecC 1.1.1.336 M ArpU family transcriptional regulator
NDOFGNNI_01651 8.9e-30 yqaO S Phage-like element PBSX protein XtrA
NDOFGNNI_01652 2.6e-68 rusA L Endodeoxyribonuclease RusA
NDOFGNNI_01654 4.4e-163 xkdC L IstB-like ATP binding protein
NDOFGNNI_01655 4.4e-121 3.1.3.16 L DnaD domain protein
NDOFGNNI_01656 1.7e-135 recT L RecT family
NDOFGNNI_01657 9.5e-175 yqaJ L YqaJ-like viral recombinase domain
NDOFGNNI_01661 4.9e-102
NDOFGNNI_01663 5.9e-17 K Helix-turn-helix XRE-family like proteins
NDOFGNNI_01664 1.1e-32 K sequence-specific DNA binding
NDOFGNNI_01666 7.6e-97 adk 2.7.4.3 F adenylate kinase activity
NDOFGNNI_01668 5.8e-94 yqaB E IrrE N-terminal-like domain
NDOFGNNI_01669 6.1e-62 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NDOFGNNI_01670 3.3e-113 tetR3 K Transcriptional regulator
NDOFGNNI_01671 1.4e-216 mepA V Multidrug transporter MatE
NDOFGNNI_01672 2.4e-166 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
NDOFGNNI_01673 1.2e-114 yrkJ S membrane transporter protein
NDOFGNNI_01674 5.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
NDOFGNNI_01675 4.2e-206 yrkH P Rhodanese Homology Domain
NDOFGNNI_01676 1e-43 perX S DsrE/DsrF-like family
NDOFGNNI_01677 1.6e-97 yrkF OP Belongs to the sulfur carrier protein TusA family
NDOFGNNI_01679 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
NDOFGNNI_01680 7.8e-39 yrkD S protein conserved in bacteria
NDOFGNNI_01681 1.3e-107 yrkC G Cupin domain
NDOFGNNI_01682 3.4e-149 bltR K helix_turn_helix, mercury resistance
NDOFGNNI_01683 3.5e-211 blt EGP Major facilitator Superfamily
NDOFGNNI_01684 9.1e-83 bltD 2.3.1.57 K FR47-like protein
NDOFGNNI_01685 5.5e-234 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NDOFGNNI_01686 3.9e-16 S YrzO-like protein
NDOFGNNI_01687 1.7e-171 yrdR EG EamA-like transporter family
NDOFGNNI_01688 5.6e-158 yrdQ K Transcriptional regulator
NDOFGNNI_01689 3.3e-197 trkA P Oxidoreductase
NDOFGNNI_01690 4.8e-147 czcD P COG1230 Co Zn Cd efflux system component
NDOFGNNI_01691 3.2e-65 yodA S tautomerase
NDOFGNNI_01692 3.5e-14 gltR K LysR substrate binding domain
NDOFGNNI_01693 3.6e-117 gltR K LysR substrate binding domain
NDOFGNNI_01694 2.5e-226 brnQ E Component of the transport system for branched-chain amino acids
NDOFGNNI_01695 9.6e-50 azlD E Branched-chain amino acid transport protein (AzlD)
NDOFGNNI_01696 3.3e-138 azlC E AzlC protein
NDOFGNNI_01697 8.2e-79 bkdR K helix_turn_helix ASNC type
NDOFGNNI_01698 2.2e-27 yrdF K ribonuclease inhibitor
NDOFGNNI_01699 2e-222 cypA C Cytochrome P450
NDOFGNNI_01701 1.2e-100 yrdC 3.5.1.19 Q Isochorismatase family
NDOFGNNI_01702 1.9e-57 S Protein of unknown function (DUF2568)
NDOFGNNI_01703 6.4e-90 yrdA S DinB family
NDOFGNNI_01704 3.2e-166 aadK G Streptomycin adenylyltransferase
NDOFGNNI_01705 4.2e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NDOFGNNI_01706 1.2e-146 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NDOFGNNI_01707 1.6e-123 yrpD S Domain of unknown function, YrpD
NDOFGNNI_01709 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
NDOFGNNI_01710 2.4e-95 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
NDOFGNNI_01711 1.3e-187 yrpG C Aldo/keto reductase family
NDOFGNNI_01712 2.3e-224 yraO C Citrate transporter
NDOFGNNI_01713 1.7e-162 yraN K Transcriptional regulator
NDOFGNNI_01714 5.9e-205 yraM S PrpF protein
NDOFGNNI_01715 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
NDOFGNNI_01716 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NDOFGNNI_01717 9.2e-155 S Alpha beta hydrolase
NDOFGNNI_01718 4.9e-60 T sh3 domain protein
NDOFGNNI_01719 5.4e-61 T sh3 domain protein
NDOFGNNI_01720 2.5e-46 E Glyoxalase-like domain
NDOFGNNI_01721 1.5e-36 yraG
NDOFGNNI_01722 6.4e-63 yraF M Spore coat protein
NDOFGNNI_01723 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NDOFGNNI_01724 7.5e-26 yraE
NDOFGNNI_01725 1.9e-49 yraD M Spore coat protein
NDOFGNNI_01726 4.3e-47 yraB K helix_turn_helix, mercury resistance
NDOFGNNI_01727 7.9e-28 yphJ 4.1.1.44 S peroxiredoxin activity
NDOFGNNI_01728 1.9e-49 adhA 1.1.1.1 C alcohol dehydrogenase
NDOFGNNI_01729 1.9e-104 adhA 1.1.1.1 C alcohol dehydrogenase
NDOFGNNI_01730 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
NDOFGNNI_01731 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NDOFGNNI_01732 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
NDOFGNNI_01733 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
NDOFGNNI_01734 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
NDOFGNNI_01735 1.5e-74 levD 2.7.1.202 G PTS system fructose IIA component
NDOFGNNI_01736 0.0 levR K PTS system fructose IIA component
NDOFGNNI_01737 6.6e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NDOFGNNI_01738 1.1e-105 yrhP E LysE type translocator
NDOFGNNI_01739 2.9e-148 yrhO K Archaeal transcriptional regulator TrmB
NDOFGNNI_01740 1.6e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
NDOFGNNI_01741 1.1e-150 rsiV S Protein of unknown function (DUF3298)
NDOFGNNI_01742 0.0 yrhL I Acyltransferase family
NDOFGNNI_01743 1.5e-46 yrhK S YrhK-like protein
NDOFGNNI_01744 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NDOFGNNI_01745 1.1e-104 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
NDOFGNNI_01746 1.1e-95 yrhH Q methyltransferase
NDOFGNNI_01749 1.8e-142 focA P Formate nitrite
NDOFGNNI_01750 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
NDOFGNNI_01751 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NDOFGNNI_01752 1.6e-77 yrhD S Protein of unknown function (DUF1641)
NDOFGNNI_01753 4.6e-35 yrhC S YrhC-like protein
NDOFGNNI_01754 6.3e-210 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NDOFGNNI_01755 6.1e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
NDOFGNNI_01756 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NDOFGNNI_01757 7.6e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
NDOFGNNI_01758 1e-25 yrzA S Protein of unknown function (DUF2536)
NDOFGNNI_01759 4.2e-63 yrrS S Protein of unknown function (DUF1510)
NDOFGNNI_01760 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
NDOFGNNI_01761 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NDOFGNNI_01762 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
NDOFGNNI_01763 2.7e-246 yegQ O COG0826 Collagenase and related proteases
NDOFGNNI_01764 7.8e-174 yegQ O Peptidase U32
NDOFGNNI_01765 5.9e-120 yrrM 2.1.1.104 S O-methyltransferase
NDOFGNNI_01766 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NDOFGNNI_01767 1.2e-45 yrzB S Belongs to the UPF0473 family
NDOFGNNI_01768 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NDOFGNNI_01769 1.7e-41 yrzL S Belongs to the UPF0297 family
NDOFGNNI_01770 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NDOFGNNI_01771 2.7e-170 yrrI S AI-2E family transporter
NDOFGNNI_01772 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NDOFGNNI_01773 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
NDOFGNNI_01774 3.6e-109 gluC P ABC transporter
NDOFGNNI_01775 7.6e-107 glnP P ABC transporter
NDOFGNNI_01776 8e-08 S Protein of unknown function (DUF3918)
NDOFGNNI_01777 9.8e-31 yrzR
NDOFGNNI_01778 1.8e-83 yrrD S protein conserved in bacteria
NDOFGNNI_01779 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NDOFGNNI_01780 1.4e-15 S COG0457 FOG TPR repeat
NDOFGNNI_01781 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NDOFGNNI_01782 4.7e-213 iscS 2.8.1.7 E Cysteine desulfurase
NDOFGNNI_01783 1.2e-70 cymR K Transcriptional regulator
NDOFGNNI_01784 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NDOFGNNI_01785 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NDOFGNNI_01786 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NDOFGNNI_01787 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
NDOFGNNI_01789 3.9e-263 lytH 3.5.1.28 M COG3103 SH3 domain protein
NDOFGNNI_01790 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NDOFGNNI_01791 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NDOFGNNI_01792 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NDOFGNNI_01793 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NDOFGNNI_01794 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
NDOFGNNI_01795 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
NDOFGNNI_01796 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NDOFGNNI_01797 1.6e-48 yrzD S Post-transcriptional regulator
NDOFGNNI_01798 9.1e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NDOFGNNI_01799 7.1e-113 yrbG S membrane
NDOFGNNI_01800 1.5e-74 yrzE S Protein of unknown function (DUF3792)
NDOFGNNI_01801 8e-39 yajC U Preprotein translocase subunit YajC
NDOFGNNI_01802 1.2e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NDOFGNNI_01803 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NDOFGNNI_01804 2.6e-18 yrzS S Protein of unknown function (DUF2905)
NDOFGNNI_01805 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NDOFGNNI_01806 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NDOFGNNI_01807 4.8e-93 bofC S BofC C-terminal domain
NDOFGNNI_01808 5.3e-253 csbX EGP Major facilitator Superfamily
NDOFGNNI_01809 2.8e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
NDOFGNNI_01810 1.9e-118 yrzF T serine threonine protein kinase
NDOFGNNI_01812 1.4e-51 S Family of unknown function (DUF5412)
NDOFGNNI_01813 4.5e-261 alsT E Sodium alanine symporter
NDOFGNNI_01814 1.6e-126 yebC K transcriptional regulatory protein
NDOFGNNI_01815 1.7e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NDOFGNNI_01816 1.7e-157 safA M spore coat assembly protein SafA
NDOFGNNI_01817 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NDOFGNNI_01818 5.4e-161 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
NDOFGNNI_01819 2.7e-307 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
NDOFGNNI_01820 1.2e-230 nifS 2.8.1.7 E Cysteine desulfurase
NDOFGNNI_01821 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
NDOFGNNI_01822 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
NDOFGNNI_01823 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
NDOFGNNI_01824 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NDOFGNNI_01825 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
NDOFGNNI_01826 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NDOFGNNI_01827 4.1e-56 ysxB J ribosomal protein
NDOFGNNI_01828 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NDOFGNNI_01829 9.2e-161 spoIVFB S Stage IV sporulation protein
NDOFGNNI_01830 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
NDOFGNNI_01831 2.5e-144 minD D Belongs to the ParA family
NDOFGNNI_01832 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NDOFGNNI_01833 1.4e-84 mreD M shape-determining protein
NDOFGNNI_01834 2.8e-157 mreC M Involved in formation and maintenance of cell shape
NDOFGNNI_01835 1.8e-184 mreB D Rod shape-determining protein MreB
NDOFGNNI_01836 5.9e-126 radC E Belongs to the UPF0758 family
NDOFGNNI_01837 2.8e-102 maf D septum formation protein Maf
NDOFGNNI_01838 1.1e-168 spoIIB S Sporulation related domain
NDOFGNNI_01839 6.6e-85 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NDOFGNNI_01840 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NDOFGNNI_01841 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NDOFGNNI_01842 1.6e-25
NDOFGNNI_01843 1.6e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NDOFGNNI_01844 1.9e-226 spoVID M stage VI sporulation protein D
NDOFGNNI_01845 2.3e-248 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NDOFGNNI_01846 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
NDOFGNNI_01847 4.4e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NDOFGNNI_01848 3e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NDOFGNNI_01849 3.6e-146 hemX O cytochrome C
NDOFGNNI_01850 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NDOFGNNI_01851 1.4e-89 ysxD
NDOFGNNI_01852 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
NDOFGNNI_01853 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NDOFGNNI_01854 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
NDOFGNNI_01855 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NDOFGNNI_01856 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NDOFGNNI_01857 2.3e-187 ysoA H Tetratricopeptide repeat
NDOFGNNI_01858 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NDOFGNNI_01859 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NDOFGNNI_01860 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NDOFGNNI_01861 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NDOFGNNI_01862 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NDOFGNNI_01863 1.2e-83 ilvN 2.2.1.6 E Acetolactate synthase
NDOFGNNI_01864 0.0 ilvB 2.2.1.6 E Acetolactate synthase
NDOFGNNI_01866 7.6e-82 ysnE K acetyltransferase
NDOFGNNI_01867 9.1e-134 ysnF S protein conserved in bacteria
NDOFGNNI_01869 1.4e-92 ysnB S Phosphoesterase
NDOFGNNI_01870 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NDOFGNNI_01871 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NDOFGNNI_01872 2.9e-196 gerM S COG5401 Spore germination protein
NDOFGNNI_01873 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NDOFGNNI_01874 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
NDOFGNNI_01875 3.3e-30 gerE K Transcriptional regulator
NDOFGNNI_01876 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
NDOFGNNI_01877 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NDOFGNNI_01878 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NDOFGNNI_01879 2.4e-107 sdhC C succinate dehydrogenase
NDOFGNNI_01880 1.2e-79 yslB S Protein of unknown function (DUF2507)
NDOFGNNI_01881 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NDOFGNNI_01882 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NDOFGNNI_01883 2e-52 trxA O Belongs to the thioredoxin family
NDOFGNNI_01884 5.7e-304 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
NDOFGNNI_01886 2.1e-177 etfA C Electron transfer flavoprotein
NDOFGNNI_01887 4.5e-135 etfB C Electron transfer flavoprotein
NDOFGNNI_01888 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NDOFGNNI_01889 2.7e-100 fadR K Transcriptional regulator
NDOFGNNI_01890 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NDOFGNNI_01891 7.3e-68 yshE S membrane
NDOFGNNI_01892 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NDOFGNNI_01893 0.0 polX L COG1796 DNA polymerase IV (family X)
NDOFGNNI_01894 1.3e-85 cvpA S membrane protein, required for colicin V production
NDOFGNNI_01895 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NDOFGNNI_01896 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NDOFGNNI_01897 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NDOFGNNI_01898 8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NDOFGNNI_01899 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NDOFGNNI_01900 2.6e-32 sspI S Belongs to the SspI family
NDOFGNNI_01901 4.4e-208 ysfB KT regulator
NDOFGNNI_01902 7.2e-264 glcD 1.1.3.15 C Glycolate oxidase subunit
NDOFGNNI_01903 1.4e-256 glcF C Glycolate oxidase
NDOFGNNI_01904 6.2e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
NDOFGNNI_01906 0.0 cstA T Carbon starvation protein
NDOFGNNI_01907 1e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
NDOFGNNI_01908 3.8e-143 araQ G transport system permease
NDOFGNNI_01909 1.4e-167 araP G carbohydrate transport
NDOFGNNI_01910 6.2e-254 araN G carbohydrate transport
NDOFGNNI_01911 1.3e-221 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NDOFGNNI_01912 1.7e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
NDOFGNNI_01913 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NDOFGNNI_01914 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
NDOFGNNI_01915 1.6e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NDOFGNNI_01916 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NDOFGNNI_01917 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
NDOFGNNI_01918 9.2e-68 ysdB S Sigma-w pathway protein YsdB
NDOFGNNI_01919 7.5e-45 ysdA S Membrane
NDOFGNNI_01920 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NDOFGNNI_01921 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NDOFGNNI_01922 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NDOFGNNI_01924 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NDOFGNNI_01925 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NDOFGNNI_01926 6.3e-131 lytT T COG3279 Response regulator of the LytR AlgR family
NDOFGNNI_01927 0.0 lytS 2.7.13.3 T Histidine kinase
NDOFGNNI_01928 1.5e-149 ysaA S HAD-hyrolase-like
NDOFGNNI_01929 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NDOFGNNI_01930 3.8e-159 ytxC S YtxC-like family
NDOFGNNI_01931 4.9e-111 ytxB S SNARE associated Golgi protein
NDOFGNNI_01932 3e-173 dnaI L Primosomal protein DnaI
NDOFGNNI_01933 3.5e-266 dnaB L Membrane attachment protein
NDOFGNNI_01934 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NDOFGNNI_01935 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NDOFGNNI_01936 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NDOFGNNI_01937 9.9e-67 ytcD K Transcriptional regulator
NDOFGNNI_01938 4.9e-205 ytbD EGP Major facilitator Superfamily
NDOFGNNI_01939 8.9e-161 ytbE S reductase
NDOFGNNI_01940 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NDOFGNNI_01941 9.5e-107 ytaF P Probably functions as a manganese efflux pump
NDOFGNNI_01942 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NDOFGNNI_01943 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NDOFGNNI_01944 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
NDOFGNNI_01945 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NDOFGNNI_01946 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
NDOFGNNI_01947 4.1e-242 icd 1.1.1.42 C isocitrate
NDOFGNNI_01948 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
NDOFGNNI_01949 4.7e-71 yeaL S membrane
NDOFGNNI_01950 2.6e-192 ytvI S sporulation integral membrane protein YtvI
NDOFGNNI_01951 1.8e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
NDOFGNNI_01952 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NDOFGNNI_01953 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NDOFGNNI_01954 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NDOFGNNI_01955 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NDOFGNNI_01956 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
NDOFGNNI_01957 0.0 dnaE 2.7.7.7 L DNA polymerase
NDOFGNNI_01958 3.2e-56 ytrH S Sporulation protein YtrH
NDOFGNNI_01959 8.2e-69 ytrI
NDOFGNNI_01960 9.2e-29
NDOFGNNI_01961 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
NDOFGNNI_01962 2.4e-47 ytpI S YtpI-like protein
NDOFGNNI_01963 8e-241 ytoI K transcriptional regulator containing CBS domains
NDOFGNNI_01964 1.1e-156 ytnM S membrane transporter protein
NDOFGNNI_01965 2.5e-236 ytnL 3.5.1.47 E hydrolase activity
NDOFGNNI_01966 4.1e-127 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
NDOFGNNI_01967 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NDOFGNNI_01968 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
NDOFGNNI_01969 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NDOFGNNI_01970 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NDOFGNNI_01971 6.4e-120 tcyM U Binding-protein-dependent transport system inner membrane component
NDOFGNNI_01972 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
NDOFGNNI_01973 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
NDOFGNNI_01974 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
NDOFGNNI_01975 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
NDOFGNNI_01976 2.9e-173 ytlI K LysR substrate binding domain
NDOFGNNI_01977 1.7e-130 ytkL S Belongs to the UPF0173 family
NDOFGNNI_01978 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NDOFGNNI_01980 8.9e-267 argH 4.3.2.1 E argininosuccinate lyase
NDOFGNNI_01981 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NDOFGNNI_01982 1.4e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
NDOFGNNI_01983 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NDOFGNNI_01984 5.4e-165 ytxK 2.1.1.72 L DNA methylase
NDOFGNNI_01985 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NDOFGNNI_01986 8.7e-70 ytfJ S Sporulation protein YtfJ
NDOFGNNI_01987 8.1e-115 ytfI S Protein of unknown function (DUF2953)
NDOFGNNI_01988 8.5e-87 yteJ S RDD family
NDOFGNNI_01989 6e-180 sppA OU signal peptide peptidase SppA
NDOFGNNI_01990 6.3e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NDOFGNNI_01991 0.0 ytcJ S amidohydrolase
NDOFGNNI_01992 2.9e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NDOFGNNI_01993 2e-29 sspB S spore protein
NDOFGNNI_01994 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NDOFGNNI_01995 5.9e-208 iscS2 2.8.1.7 E Cysteine desulfurase
NDOFGNNI_01996 1.4e-237 brnQ E Component of the transport system for branched-chain amino acids
NDOFGNNI_01997 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NDOFGNNI_01998 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NDOFGNNI_01999 3.4e-109 yttP K Transcriptional regulator
NDOFGNNI_02000 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
NDOFGNNI_02001 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
NDOFGNNI_02002 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NDOFGNNI_02004 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NDOFGNNI_02005 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NDOFGNNI_02006 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NDOFGNNI_02007 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
NDOFGNNI_02008 1.9e-225 acuC BQ histone deacetylase
NDOFGNNI_02009 1.4e-125 motS N Flagellar motor protein
NDOFGNNI_02010 7.1e-147 motA N flagellar motor
NDOFGNNI_02011 1.7e-182 ccpA K catabolite control protein A
NDOFGNNI_02012 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NDOFGNNI_02013 4.4e-55 ytxJ O Protein of unknown function (DUF2847)
NDOFGNNI_02014 6.6e-17 ytxH S COG4980 Gas vesicle protein
NDOFGNNI_02015 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NDOFGNNI_02016 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NDOFGNNI_02017 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
NDOFGNNI_02018 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NDOFGNNI_02019 9.8e-149 ytpQ S Belongs to the UPF0354 family
NDOFGNNI_02020 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NDOFGNNI_02021 1.7e-78 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
NDOFGNNI_02022 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
NDOFGNNI_02023 2.2e-51 ytzB S small secreted protein
NDOFGNNI_02024 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
NDOFGNNI_02025 4.6e-149 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
NDOFGNNI_02026 2e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NDOFGNNI_02027 2e-45 ytzH S YtzH-like protein
NDOFGNNI_02028 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
NDOFGNNI_02029 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
NDOFGNNI_02030 7.2e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NDOFGNNI_02031 1.3e-165 ytlQ
NDOFGNNI_02032 2.9e-99 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NDOFGNNI_02033 9.5e-172 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NDOFGNNI_02034 3e-270 pepV 3.5.1.18 E Dipeptidase
NDOFGNNI_02035 7.2e-226 pbuO S permease
NDOFGNNI_02036 4.2e-201 ythQ U Bacterial ABC transporter protein EcsB
NDOFGNNI_02037 4.8e-131 ythP V ABC transporter
NDOFGNNI_02038 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
NDOFGNNI_02039 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NDOFGNNI_02040 6.1e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NDOFGNNI_02041 8.2e-232 ytfP S HI0933-like protein
NDOFGNNI_02042 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
NDOFGNNI_02043 3.1e-26 yteV S Sporulation protein Cse60
NDOFGNNI_02044 4.5e-115 yteU S Integral membrane protein
NDOFGNNI_02045 6.6e-256 yteT S Oxidoreductase family, C-terminal alpha/beta domain
NDOFGNNI_02046 3.9e-72 yteS G transport
NDOFGNNI_02047 1.6e-218 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
NDOFGNNI_02048 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NDOFGNNI_02049 0.0 ytdP K Transcriptional regulator
NDOFGNNI_02050 6.2e-290 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
NDOFGNNI_02051 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
NDOFGNNI_02052 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
NDOFGNNI_02053 6.3e-221 bioI 1.14.14.46 C Cytochrome P450
NDOFGNNI_02054 8.4e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NDOFGNNI_02055 2.9e-125 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NDOFGNNI_02056 2.2e-213 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NDOFGNNI_02057 1.3e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NDOFGNNI_02058 2e-140 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NDOFGNNI_02059 2e-171 ytaP S Acetyl xylan esterase (AXE1)
NDOFGNNI_02060 6.6e-190 msmR K Transcriptional regulator
NDOFGNNI_02061 1.4e-242 msmE G Bacterial extracellular solute-binding protein
NDOFGNNI_02062 6.2e-168 amyD P ABC transporter
NDOFGNNI_02063 8.3e-143 amyC P ABC transporter (permease)
NDOFGNNI_02064 2.2e-251 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NDOFGNNI_02065 2.1e-51 ytwF P Sulfurtransferase
NDOFGNNI_02066 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NDOFGNNI_02067 7.7e-55 ytvB S Protein of unknown function (DUF4257)
NDOFGNNI_02068 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NDOFGNNI_02069 5.1e-210 yttB EGP Major facilitator Superfamily
NDOFGNNI_02070 1.9e-42 yttA 2.7.13.3 S Pfam Transposase IS66
NDOFGNNI_02071 0.0 bceB V ABC transporter (permease)
NDOFGNNI_02072 1.1e-138 bceA V ABC transporter, ATP-binding protein
NDOFGNNI_02073 4e-184 T PhoQ Sensor
NDOFGNNI_02074 1.5e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NDOFGNNI_02075 1.4e-232 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
NDOFGNNI_02076 3.1e-127 ytrE V ABC transporter, ATP-binding protein
NDOFGNNI_02077 4.5e-148
NDOFGNNI_02078 1e-152 P ABC-2 family transporter protein
NDOFGNNI_02079 4.2e-161 ytrB P abc transporter atp-binding protein
NDOFGNNI_02080 5.1e-66 ytrA K GntR family transcriptional regulator
NDOFGNNI_02082 6.7e-41 ytzC S Protein of unknown function (DUF2524)
NDOFGNNI_02083 8.1e-190 yhcC S Fe-S oxidoreductase
NDOFGNNI_02084 2.2e-105 ytqB J Putative rRNA methylase
NDOFGNNI_02085 7.5e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
NDOFGNNI_02086 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
NDOFGNNI_02087 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NDOFGNNI_02088 3.2e-256 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
NDOFGNNI_02089 0.0 asnB 6.3.5.4 E Asparagine synthase
NDOFGNNI_02090 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NDOFGNNI_02091 7.5e-310 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NDOFGNNI_02092 1.2e-38 ytmB S Protein of unknown function (DUF2584)
NDOFGNNI_02093 6.7e-147 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NDOFGNNI_02094 8e-188 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NDOFGNNI_02095 1.4e-144 ytlC P ABC transporter
NDOFGNNI_02096 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NDOFGNNI_02097 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
NDOFGNNI_02098 5.4e-63 ytkC S Bacteriophage holin family
NDOFGNNI_02099 2.1e-76 dps P Belongs to the Dps family
NDOFGNNI_02101 3.6e-73 ytkA S YtkA-like
NDOFGNNI_02102 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NDOFGNNI_02103 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NDOFGNNI_02104 3.6e-41 rpmE2 J Ribosomal protein L31
NDOFGNNI_02105 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
NDOFGNNI_02106 7.3e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NDOFGNNI_02107 1.1e-24 S Domain of Unknown Function (DUF1540)
NDOFGNNI_02108 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
NDOFGNNI_02109 3.2e-234 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NDOFGNNI_02110 1e-139 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NDOFGNNI_02111 1.7e-168 troA P Belongs to the bacterial solute-binding protein 9 family
NDOFGNNI_02112 7.8e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NDOFGNNI_02113 2.8e-271 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NDOFGNNI_02114 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NDOFGNNI_02115 2.8e-151 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NDOFGNNI_02116 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NDOFGNNI_02117 9.4e-272 menF 5.4.4.2 HQ Isochorismate synthase
NDOFGNNI_02118 4.4e-132 dksA T COG1734 DnaK suppressor protein
NDOFGNNI_02119 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
NDOFGNNI_02120 4.4e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NDOFGNNI_02121 6.3e-179 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
NDOFGNNI_02122 3e-234 ytcC M Glycosyltransferase Family 4
NDOFGNNI_02124 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
NDOFGNNI_02125 1.8e-217 cotSA M Glycosyl transferases group 1
NDOFGNNI_02126 4.8e-204 cotI S Spore coat protein
NDOFGNNI_02127 9.9e-77 tspO T membrane
NDOFGNNI_02128 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NDOFGNNI_02129 8.4e-284 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
NDOFGNNI_02130 2.9e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
NDOFGNNI_02131 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NDOFGNNI_02132 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NDOFGNNI_02141 7.8e-08
NDOFGNNI_02142 1.3e-09
NDOFGNNI_02149 2e-08
NDOFGNNI_02154 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
NDOFGNNI_02155 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
NDOFGNNI_02156 3.1e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NDOFGNNI_02157 5.8e-195 yxbF K Bacterial regulatory proteins, tetR family
NDOFGNNI_02158 4.8e-151 IQ Enoyl-(Acyl carrier protein) reductase
NDOFGNNI_02160 0.0 htpG O Molecular chaperone. Has ATPase activity
NDOFGNNI_02161 2.3e-246 csbC EGP Major facilitator Superfamily
NDOFGNNI_02162 8.3e-48 yxcD S Protein of unknown function (DUF2653)
NDOFGNNI_02164 8.3e-176 iolS C Aldo keto reductase
NDOFGNNI_02165 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
NDOFGNNI_02166 7.4e-280 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NDOFGNNI_02167 1.1e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NDOFGNNI_02168 2.5e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NDOFGNNI_02169 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NDOFGNNI_02170 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NDOFGNNI_02171 1.3e-235 iolF EGP Major facilitator Superfamily
NDOFGNNI_02172 1.4e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NDOFGNNI_02173 8.6e-167 iolH G Xylose isomerase-like TIM barrel
NDOFGNNI_02174 2.1e-138 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NDOFGNNI_02175 5.4e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NDOFGNNI_02176 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NDOFGNNI_02177 2.6e-180 T PhoQ Sensor
NDOFGNNI_02178 9.4e-141 yxdL V ABC transporter, ATP-binding protein
NDOFGNNI_02179 0.0 yxdM V ABC transporter (permease)
NDOFGNNI_02180 1.5e-58 yxeA S Protein of unknown function (DUF1093)
NDOFGNNI_02181 6e-177 fhuD P ABC transporter
NDOFGNNI_02182 8.5e-69
NDOFGNNI_02183 1.9e-16 yxeD
NDOFGNNI_02184 1.2e-16 yxeE
NDOFGNNI_02187 4.4e-149 yidA S hydrolases of the HAD superfamily
NDOFGNNI_02188 1.5e-183 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
NDOFGNNI_02189 1.8e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NDOFGNNI_02190 1.6e-93 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NDOFGNNI_02191 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
NDOFGNNI_02192 1.3e-106 yxeN P COG0765 ABC-type amino acid transport system, permease component
NDOFGNNI_02193 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
NDOFGNNI_02194 3.8e-215 yxeP 3.5.1.47 E hydrolase activity
NDOFGNNI_02195 4.1e-253 yxeQ S MmgE/PrpD family
NDOFGNNI_02196 4.1e-198 eutH E Ethanolamine utilisation protein, EutH
NDOFGNNI_02197 2.6e-152 yxxB S Domain of Unknown Function (DUF1206)
NDOFGNNI_02198 3.9e-173 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NDOFGNNI_02199 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NDOFGNNI_02200 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NDOFGNNI_02201 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
NDOFGNNI_02202 3.4e-250 lysP E amino acid
NDOFGNNI_02203 1.8e-178 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NDOFGNNI_02204 9.7e-236 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
NDOFGNNI_02205 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NDOFGNNI_02206 4.9e-282 hutH 4.3.1.3 E Histidine ammonia-lyase
NDOFGNNI_02207 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
NDOFGNNI_02208 3.2e-13 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
NDOFGNNI_02210 9.4e-10 S Oxidoreductase
NDOFGNNI_02211 3.3e-277 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NDOFGNNI_02212 4.6e-21 S Domain of unknown function (DUF5082)
NDOFGNNI_02213 1.4e-38 yxiC S Family of unknown function (DUF5344)
NDOFGNNI_02214 2.2e-280 S nuclease activity
NDOFGNNI_02215 4.2e-47
NDOFGNNI_02216 5.5e-53
NDOFGNNI_02217 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NDOFGNNI_02218 1.1e-280 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NDOFGNNI_02219 1.8e-72 yxiE T Belongs to the universal stress protein A family
NDOFGNNI_02220 7.1e-122 1.14.11.45 E 2OG-Fe dioxygenase
NDOFGNNI_02221 8.2e-126 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NDOFGNNI_02222 3.9e-165 yxxF EG EamA-like transporter family
NDOFGNNI_02223 0.0 wapA M COG3209 Rhs family protein
NDOFGNNI_02224 1.5e-71 yxxG
NDOFGNNI_02225 1.7e-84
NDOFGNNI_02226 6.4e-63
NDOFGNNI_02227 3.7e-75 yxiG
NDOFGNNI_02228 2.3e-140
NDOFGNNI_02229 1.6e-93 yxiI S Protein of unknown function (DUF2716)
NDOFGNNI_02230 5.7e-46 yxiJ S YxiJ-like protein
NDOFGNNI_02233 2.2e-210 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
NDOFGNNI_02234 5.6e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NDOFGNNI_02235 3.4e-228 yxiO S COG2270 Permeases of the major facilitator superfamily
NDOFGNNI_02236 6.2e-112
NDOFGNNI_02237 8.3e-151 licT K transcriptional antiterminator
NDOFGNNI_02238 7.3e-143 exoK GH16 M licheninase activity
NDOFGNNI_02239 6.6e-224 citH C Citrate transporter
NDOFGNNI_02240 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
NDOFGNNI_02241 3e-47 yxiS
NDOFGNNI_02242 2.6e-102 T Domain of unknown function (DUF4163)
NDOFGNNI_02243 4.1e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NDOFGNNI_02244 1e-156 rlmA 2.1.1.187 Q Methyltransferase domain
NDOFGNNI_02245 7.5e-253 yxjC EG COG2610 H gluconate symporter and related permeases
NDOFGNNI_02246 1.2e-129 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NDOFGNNI_02247 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NDOFGNNI_02248 2.8e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NDOFGNNI_02249 2.4e-217 yxjG 2.1.1.14 E Methionine synthase
NDOFGNNI_02250 1.5e-219 yxjG 2.1.1.14 E Methionine synthase
NDOFGNNI_02251 6.7e-84 yxjI S LURP-one-related
NDOFGNNI_02254 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NDOFGNNI_02255 1e-111 K helix_turn_helix, Lux Regulon
NDOFGNNI_02256 4.1e-191 yxjM T Signal transduction histidine kinase
NDOFGNNI_02257 3.4e-77 S Protein of unknown function (DUF1453)
NDOFGNNI_02258 4.4e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NDOFGNNI_02259 1.5e-137
NDOFGNNI_02260 7.3e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NDOFGNNI_02261 1.2e-274 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NDOFGNNI_02262 1.2e-163 lrp QT PucR C-terminal helix-turn-helix domain
NDOFGNNI_02263 5.9e-205 msmK P Belongs to the ABC transporter superfamily
NDOFGNNI_02264 1.1e-153 yxkH G Polysaccharide deacetylase
NDOFGNNI_02266 3.5e-310 3.4.24.84 O Peptidase family M48
NDOFGNNI_02267 1.5e-229 cimH C COG3493 Na citrate symporter
NDOFGNNI_02268 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
NDOFGNNI_02269 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
NDOFGNNI_02270 3.5e-310 cydD V ATP-binding
NDOFGNNI_02271 0.0 cydD V ATP-binding protein
NDOFGNNI_02272 1.2e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NDOFGNNI_02273 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
NDOFGNNI_02274 1.1e-84 sigY K Belongs to the sigma-70 factor family. ECF subfamily
NDOFGNNI_02275 3.9e-48 yxlC S Family of unknown function (DUF5345)
NDOFGNNI_02276 1.2e-31
NDOFGNNI_02277 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
NDOFGNNI_02278 4.1e-164 yxlF V ABC transporter, ATP-binding protein
NDOFGNNI_02279 4.8e-137 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NDOFGNNI_02280 5.4e-212 yxlH EGP Major facilitator Superfamily
NDOFGNNI_02281 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NDOFGNNI_02282 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NDOFGNNI_02283 1.1e-19 yxzF
NDOFGNNI_02284 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
NDOFGNNI_02285 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
NDOFGNNI_02286 1.1e-248 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NDOFGNNI_02287 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
NDOFGNNI_02288 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NDOFGNNI_02289 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NDOFGNNI_02290 6.2e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
NDOFGNNI_02291 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NDOFGNNI_02292 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NDOFGNNI_02293 1.2e-232 dltB M membrane protein involved in D-alanine export
NDOFGNNI_02294 5.7e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NDOFGNNI_02295 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
NDOFGNNI_02296 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
NDOFGNNI_02297 1e-130 ynfM EGP Major facilitator Superfamily
NDOFGNNI_02298 9.4e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
NDOFGNNI_02299 1.4e-92 K Helix-turn-helix XRE-family like proteins
NDOFGNNI_02300 7.5e-250 ywaD 3.4.11.10, 3.4.11.6 S PA domain
NDOFGNNI_02301 1.7e-232 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NDOFGNNI_02302 2.3e-87 ywaE K Transcriptional regulator
NDOFGNNI_02303 2.4e-122 ywaF S Integral membrane protein
NDOFGNNI_02304 2.9e-167 gspA M General stress
NDOFGNNI_02305 1.2e-152 sacY K transcriptional antiterminator
NDOFGNNI_02306 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NDOFGNNI_02307 2.6e-272 epr 3.4.21.62 O Belongs to the peptidase S8 family
NDOFGNNI_02308 5.4e-245 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NDOFGNNI_02309 1.8e-119 ywbB S Protein of unknown function (DUF2711)
NDOFGNNI_02310 4.4e-67 ywbC 4.4.1.5 E glyoxalase
NDOFGNNI_02311 1.6e-219 ywbD 2.1.1.191 J Methyltransferase
NDOFGNNI_02312 2.3e-27 ywbE S Uncharacterized conserved protein (DUF2196)
NDOFGNNI_02313 3.1e-207 ywbF EGP Major facilitator Superfamily
NDOFGNNI_02314 2.3e-111 ywbG M effector of murein hydrolase
NDOFGNNI_02315 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NDOFGNNI_02316 4.3e-153 ywbI K Transcriptional regulator
NDOFGNNI_02317 1.1e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NDOFGNNI_02318 4.5e-115 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NDOFGNNI_02319 9e-254 P COG0672 High-affinity Fe2 Pb2 permease
NDOFGNNI_02320 3.2e-185 ycdO P periplasmic lipoprotein involved in iron transport
NDOFGNNI_02321 4.9e-224 ywbN P Dyp-type peroxidase family protein
NDOFGNNI_02322 9e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NDOFGNNI_02323 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NDOFGNNI_02324 1.9e-47 ywcB S Protein of unknown function, DUF485
NDOFGNNI_02326 1.1e-121 ywcC K transcriptional regulator
NDOFGNNI_02327 9.5e-60 gtcA S GtrA-like protein
NDOFGNNI_02328 6.9e-228 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NDOFGNNI_02329 1.5e-302 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NDOFGNNI_02330 1e-35 ywzA S membrane
NDOFGNNI_02331 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NDOFGNNI_02332 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NDOFGNNI_02333 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NDOFGNNI_02334 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NDOFGNNI_02335 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
NDOFGNNI_02336 2.9e-202 rodA D Belongs to the SEDS family
NDOFGNNI_02337 6.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
NDOFGNNI_02338 3.3e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NDOFGNNI_02339 0.0 vpr O Belongs to the peptidase S8 family
NDOFGNNI_02341 7e-150 sacT K transcriptional antiterminator
NDOFGNNI_02342 2.3e-139 focA P Formate/nitrite transporter
NDOFGNNI_02343 1.8e-251 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NDOFGNNI_02344 1.5e-280 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
NDOFGNNI_02345 2e-28 ywdA
NDOFGNNI_02346 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NDOFGNNI_02347 1.3e-57 pex K Transcriptional regulator PadR-like family
NDOFGNNI_02348 6.2e-67 ywdD
NDOFGNNI_02350 1.2e-151 ywdF GT2,GT4 S Glycosyltransferase like family 2
NDOFGNNI_02351 1.1e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NDOFGNNI_02352 2.2e-262 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NDOFGNNI_02353 1.7e-48 ywdI S Family of unknown function (DUF5327)
NDOFGNNI_02354 3.7e-238 ywdJ F Xanthine uracil
NDOFGNNI_02355 4.3e-59 ywdK S small membrane protein
NDOFGNNI_02356 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NDOFGNNI_02357 2e-143 spsA M Spore Coat
NDOFGNNI_02358 2.1e-268 spsB M Capsule polysaccharide biosynthesis protein
NDOFGNNI_02359 2.3e-223 spsC E Belongs to the DegT DnrJ EryC1 family
NDOFGNNI_02360 1.7e-162 spsD 2.3.1.210 K Spore Coat
NDOFGNNI_02361 2.7e-213 spsE 2.5.1.56 M acid synthase
NDOFGNNI_02362 9.1e-130 spsF M Spore Coat
NDOFGNNI_02363 1.5e-186 spsG M Spore Coat
NDOFGNNI_02364 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NDOFGNNI_02365 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NDOFGNNI_02366 1.5e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NDOFGNNI_02367 1.1e-85 spsL 5.1.3.13 M Spore Coat
NDOFGNNI_02368 5.8e-77
NDOFGNNI_02369 1.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NDOFGNNI_02370 3.5e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NDOFGNNI_02371 0.0 rocB E arginine degradation protein
NDOFGNNI_02372 6.3e-249 lysP E amino acid
NDOFGNNI_02373 3.9e-205 ywfA EGP Major facilitator Superfamily
NDOFGNNI_02374 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NDOFGNNI_02375 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NDOFGNNI_02376 4.3e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NDOFGNNI_02377 4.7e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NDOFGNNI_02378 1.2e-208 bacE EGP Major facilitator Superfamily
NDOFGNNI_02379 2.3e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
NDOFGNNI_02380 2e-135 IQ Enoyl-(Acyl carrier protein) reductase
NDOFGNNI_02381 1.1e-146 ywfI C May function as heme-dependent peroxidase
NDOFGNNI_02382 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
NDOFGNNI_02383 9.2e-156 cysL K Transcriptional regulator
NDOFGNNI_02384 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NDOFGNNI_02385 9.8e-158 ywfM EG EamA-like transporter family
NDOFGNNI_02386 1e-110 rsfA_1
NDOFGNNI_02387 3.1e-36 ywzC S Belongs to the UPF0741 family
NDOFGNNI_02388 4.3e-255 ywfO S COG1078 HD superfamily phosphohydrolases
NDOFGNNI_02389 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
NDOFGNNI_02390 1.5e-77 yffB K Transcriptional regulator
NDOFGNNI_02391 2e-237 mmr U Major Facilitator Superfamily
NDOFGNNI_02393 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NDOFGNNI_02394 3.3e-71 ywhA K Transcriptional regulator
NDOFGNNI_02395 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
NDOFGNNI_02396 5.1e-119 ywhC S Peptidase family M50
NDOFGNNI_02397 2e-94 ywhD S YwhD family
NDOFGNNI_02398 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NDOFGNNI_02399 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NDOFGNNI_02400 6e-168 speB 3.5.3.11 E Belongs to the arginase family
NDOFGNNI_02402 1.4e-57 V ATPases associated with a variety of cellular activities
NDOFGNNI_02405 1.7e-20
NDOFGNNI_02408 2.6e-78 S aspartate phosphatase
NDOFGNNI_02409 2.7e-191 ywhK CO amine dehydrogenase activity
NDOFGNNI_02410 1.4e-243 ywhL CO amine dehydrogenase activity
NDOFGNNI_02412 2.3e-248 L Peptidase, M16
NDOFGNNI_02413 8.3e-213 2.7.1.26, 2.7.7.2 L Peptidase, M16
NDOFGNNI_02414 1.6e-233 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
NDOFGNNI_02415 3.7e-131 cbiO V ABC transporter
NDOFGNNI_02417 1.4e-269 C Fe-S oxidoreductases
NDOFGNNI_02418 1e-07 S Bacteriocin subtilosin A
NDOFGNNI_02419 4.7e-73 ywiB S protein conserved in bacteria
NDOFGNNI_02420 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NDOFGNNI_02421 9.8e-214 narK P COG2223 Nitrate nitrite transporter
NDOFGNNI_02422 2.6e-129 fnr K helix_turn_helix, cAMP Regulatory protein
NDOFGNNI_02423 1.7e-139 ywiC S YwiC-like protein
NDOFGNNI_02424 7e-86 arfM T cyclic nucleotide binding
NDOFGNNI_02425 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NDOFGNNI_02426 9.7e-296 narH 1.7.5.1 C Nitrate reductase, beta
NDOFGNNI_02427 6.2e-94 narJ 1.7.5.1 C nitrate reductase
NDOFGNNI_02428 1.8e-124 narI 1.7.5.1 C nitrate reductase, gamma
NDOFGNNI_02429 1.6e-285 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NDOFGNNI_02430 0.0 ywjA V ABC transporter
NDOFGNNI_02431 4.8e-96 ywjB H RibD C-terminal domain
NDOFGNNI_02432 2.7e-42 ywjC
NDOFGNNI_02433 1.5e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NDOFGNNI_02434 2.3e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NDOFGNNI_02435 0.0 fadF C COG0247 Fe-S oxidoreductase
NDOFGNNI_02436 4.4e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
NDOFGNNI_02437 1.1e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NDOFGNNI_02438 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NDOFGNNI_02439 1.8e-90 ywjG S Domain of unknown function (DUF2529)
NDOFGNNI_02440 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
NDOFGNNI_02441 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
NDOFGNNI_02442 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NDOFGNNI_02443 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NDOFGNNI_02444 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
NDOFGNNI_02445 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NDOFGNNI_02446 1.1e-32 rpmE J Binds the 23S rRNA
NDOFGNNI_02447 5.4e-104 tdk 2.7.1.21 F thymidine kinase
NDOFGNNI_02448 0.0 sfcA 1.1.1.38 C malic enzyme
NDOFGNNI_02449 8.6e-160 ywkB S Membrane transport protein
NDOFGNNI_02450 7.1e-90 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NDOFGNNI_02451 1.2e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NDOFGNNI_02452 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NDOFGNNI_02453 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NDOFGNNI_02455 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
NDOFGNNI_02456 6.1e-112 spoIIR S stage II sporulation protein R
NDOFGNNI_02457 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
NDOFGNNI_02458 8.1e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NDOFGNNI_02459 1.7e-91 mntP P Probably functions as a manganese efflux pump
NDOFGNNI_02460 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NDOFGNNI_02461 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
NDOFGNNI_02462 7.2e-95 ywlG S Belongs to the UPF0340 family
NDOFGNNI_02463 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NDOFGNNI_02464 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NDOFGNNI_02465 2.5e-62 atpI S ATP synthase
NDOFGNNI_02466 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
NDOFGNNI_02467 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NDOFGNNI_02468 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NDOFGNNI_02469 5.9e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NDOFGNNI_02470 1e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NDOFGNNI_02471 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NDOFGNNI_02472 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NDOFGNNI_02473 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NDOFGNNI_02474 3.1e-86 ywmA
NDOFGNNI_02475 1.3e-32 ywzB S membrane
NDOFGNNI_02476 8.2e-134 ywmB S TATA-box binding
NDOFGNNI_02477 7.9e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NDOFGNNI_02478 1e-174 spoIID D Stage II sporulation protein D
NDOFGNNI_02479 5.1e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
NDOFGNNI_02480 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
NDOFGNNI_02482 3.8e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NDOFGNNI_02483 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NDOFGNNI_02484 1.3e-103 S response regulator aspartate phosphatase
NDOFGNNI_02485 8.7e-84 ywmF S Peptidase M50
NDOFGNNI_02486 3.8e-11 csbD K CsbD-like
NDOFGNNI_02487 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NDOFGNNI_02488 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NDOFGNNI_02489 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NDOFGNNI_02490 1.7e-64 ywnA K Transcriptional regulator
NDOFGNNI_02491 1.2e-112 ywnB S NAD(P)H-binding
NDOFGNNI_02492 1.7e-58 ywnC S Family of unknown function (DUF5362)
NDOFGNNI_02493 1.6e-143 mta K transcriptional
NDOFGNNI_02494 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NDOFGNNI_02495 2.2e-70 ywnF S Family of unknown function (DUF5392)
NDOFGNNI_02496 5.7e-09 ywnC S Family of unknown function (DUF5362)
NDOFGNNI_02497 4.1e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
NDOFGNNI_02498 1.5e-115 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
NDOFGNNI_02499 3.5e-73 ywnJ S VanZ like family
NDOFGNNI_02500 5.9e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
NDOFGNNI_02501 1.6e-58 nrgB K Belongs to the P(II) protein family
NDOFGNNI_02502 4.3e-225 amt P Ammonium transporter
NDOFGNNI_02503 1.4e-75
NDOFGNNI_02504 2e-103 phzA Q Isochorismatase family
NDOFGNNI_02505 7e-240 ywoD EGP Major facilitator superfamily
NDOFGNNI_02506 1.2e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
NDOFGNNI_02507 1.2e-231 ywoF P Right handed beta helix region
NDOFGNNI_02508 2.7e-211 ywoG EGP Major facilitator Superfamily
NDOFGNNI_02509 2.1e-70 ywoH K COG1846 Transcriptional regulators
NDOFGNNI_02510 3e-44 spoIIID K Stage III sporulation protein D
NDOFGNNI_02511 3.5e-180 mbl D Rod shape-determining protein
NDOFGNNI_02512 2.9e-124 flhO N flagellar basal body
NDOFGNNI_02513 2.6e-141 flhP N flagellar basal body
NDOFGNNI_02514 2.3e-198 S aspartate phosphatase
NDOFGNNI_02515 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NDOFGNNI_02516 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NDOFGNNI_02517 0.0 ywpD T PhoQ Sensor
NDOFGNNI_02518 3.1e-174 M1-574 T Transcriptional regulatory protein, C terminal
NDOFGNNI_02519 0.0 M1-568 M cell wall anchor domain
NDOFGNNI_02520 6.7e-84 srtA 3.4.22.70 M Sortase family
NDOFGNNI_02521 2.4e-66 ywpF S YwpF-like protein
NDOFGNNI_02522 2.4e-65 ywpG
NDOFGNNI_02523 3.7e-57 ssbB L Single-stranded DNA-binding protein
NDOFGNNI_02524 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
NDOFGNNI_02525 2.2e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
NDOFGNNI_02526 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NDOFGNNI_02527 6e-307 ywqB S SWIM zinc finger
NDOFGNNI_02528 1.2e-17
NDOFGNNI_02529 2e-116 ywqC M biosynthesis protein
NDOFGNNI_02530 1.1e-119 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
NDOFGNNI_02531 5.5e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
NDOFGNNI_02532 1.7e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NDOFGNNI_02533 2.4e-152 ywqG S Domain of unknown function (DUF1963)
NDOFGNNI_02534 9.7e-23 S Domain of unknown function (DUF5082)
NDOFGNNI_02535 3.9e-38 ywqI S Family of unknown function (DUF5344)
NDOFGNNI_02536 2.1e-242 ywqJ S Pre-toxin TG
NDOFGNNI_02537 3.9e-25
NDOFGNNI_02538 3.9e-117 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NDOFGNNI_02539 4.9e-162 K Transcriptional regulator
NDOFGNNI_02540 2.4e-98 ywqN S NAD(P)H-dependent
NDOFGNNI_02542 9.9e-89 ywrA P COG2059 Chromate transport protein ChrA
NDOFGNNI_02543 1.2e-103 ywrB P Chromate transporter
NDOFGNNI_02544 8e-82 ywrC K Transcriptional regulator
NDOFGNNI_02545 1.5e-307 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NDOFGNNI_02546 5e-54 S Domain of unknown function (DUF4181)
NDOFGNNI_02547 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NDOFGNNI_02548 3.7e-12
NDOFGNNI_02549 3.5e-210 cotH M Spore Coat
NDOFGNNI_02550 7.6e-131 cotB
NDOFGNNI_02551 4.5e-123 ywrJ
NDOFGNNI_02552 5.5e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NDOFGNNI_02553 1.1e-169 alsR K LysR substrate binding domain
NDOFGNNI_02554 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NDOFGNNI_02555 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
NDOFGNNI_02556 1.7e-96 ywrO S NADPH-quinone reductase (modulator of drug activity B)
NDOFGNNI_02557 3.6e-48 ywsA S Protein of unknown function (DUF3892)
NDOFGNNI_02558 1.2e-91 batE T Sh3 type 3 domain protein
NDOFGNNI_02559 1.1e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
NDOFGNNI_02560 1.8e-152 rbsC G Belongs to the binding-protein-dependent transport system permease family
NDOFGNNI_02561 9.5e-275 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NDOFGNNI_02562 1.4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NDOFGNNI_02563 2.7e-160 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NDOFGNNI_02564 9.3e-178 rbsR K transcriptional
NDOFGNNI_02565 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
NDOFGNNI_02566 8.6e-70 pgsC S biosynthesis protein
NDOFGNNI_02567 3.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NDOFGNNI_02568 3.6e-21 ywtC
NDOFGNNI_02569 6.5e-238 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NDOFGNNI_02570 7.7e-160 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
NDOFGNNI_02571 1.1e-170 ywtF K Transcriptional regulator
NDOFGNNI_02572 1.9e-248 ywtG EGP Major facilitator Superfamily
NDOFGNNI_02573 2.4e-214 gerAC S Spore germination protein
NDOFGNNI_02574 5.7e-200 gerBB E Spore germination protein
NDOFGNNI_02575 3.5e-266 gerBA EG Spore germination protein
NDOFGNNI_02576 7.1e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
NDOFGNNI_02577 1.6e-216 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NDOFGNNI_02578 3.5e-260
NDOFGNNI_02579 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NDOFGNNI_02580 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NDOFGNNI_02581 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
NDOFGNNI_02582 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
NDOFGNNI_02583 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NDOFGNNI_02584 1.1e-150 tagG GM Transport permease protein
NDOFGNNI_02585 1.8e-279 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NDOFGNNI_02586 1.6e-100 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NDOFGNNI_02588 1.4e-256 ggaA M Glycosyltransferase like family 2
NDOFGNNI_02589 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NDOFGNNI_02590 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NDOFGNNI_02591 2.4e-217 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NDOFGNNI_02592 1.8e-162 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NDOFGNNI_02593 6e-38
NDOFGNNI_02594 0.0 lytB 3.5.1.28 D Stage II sporulation protein
NDOFGNNI_02595 1.9e-267 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NDOFGNNI_02596 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NDOFGNNI_02597 7.4e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NDOFGNNI_02598 1e-218 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
NDOFGNNI_02599 2e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NDOFGNNI_02600 6.3e-263 tuaE M Teichuronic acid biosynthesis protein
NDOFGNNI_02601 9.5e-113 tuaF M protein involved in exopolysaccharide biosynthesis
NDOFGNNI_02602 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
NDOFGNNI_02603 5e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
NDOFGNNI_02604 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NDOFGNNI_02605 6e-163 yvhJ K Transcriptional regulator
NDOFGNNI_02606 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
NDOFGNNI_02607 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NDOFGNNI_02608 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NDOFGNNI_02609 7.3e-155 degV S protein conserved in bacteria
NDOFGNNI_02610 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NDOFGNNI_02611 5.7e-46 comFB S Late competence development protein ComFB
NDOFGNNI_02612 2.7e-129 comFC S Phosphoribosyl transferase domain
NDOFGNNI_02613 7e-74 yvyF S flagellar protein
NDOFGNNI_02614 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
NDOFGNNI_02615 2.4e-78 flgN NOU FlgN protein
NDOFGNNI_02616 1.2e-264 flgK N flagellar hook-associated protein
NDOFGNNI_02617 1.1e-156 flgL N Belongs to the bacterial flagellin family
NDOFGNNI_02618 2.2e-49 yviE
NDOFGNNI_02619 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NDOFGNNI_02620 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NDOFGNNI_02621 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NDOFGNNI_02622 6.1e-57 flaG N flagellar protein FlaG
NDOFGNNI_02623 1.3e-266 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NDOFGNNI_02624 2.9e-69 fliS N flagellar protein FliS
NDOFGNNI_02625 1.9e-08 fliT S bacterial-type flagellum organization
NDOFGNNI_02626 2.8e-66
NDOFGNNI_02627 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NDOFGNNI_02628 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NDOFGNNI_02629 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NDOFGNNI_02630 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
NDOFGNNI_02631 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
NDOFGNNI_02632 1.6e-123 ftsE D cell division ATP-binding protein FtsE
NDOFGNNI_02633 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NDOFGNNI_02634 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
NDOFGNNI_02635 5.3e-56 swrA S Swarming motility protein
NDOFGNNI_02636 1.1e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NDOFGNNI_02637 7.9e-228 yvkA EGP Major facilitator Superfamily
NDOFGNNI_02638 7e-101 yvkB K Transcriptional regulator
NDOFGNNI_02639 0.0 yvkC 2.7.9.2 GT Phosphotransferase
NDOFGNNI_02640 1.2e-30 csbA S protein conserved in bacteria
NDOFGNNI_02641 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NDOFGNNI_02642 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NDOFGNNI_02643 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NDOFGNNI_02644 6.7e-34 yvkN
NDOFGNNI_02645 8e-49 yvlA
NDOFGNNI_02646 3.4e-168 yvlB S Putative adhesin
NDOFGNNI_02647 2.6e-26 pspB KT PspC domain
NDOFGNNI_02648 1.2e-50 yvlD S Membrane
NDOFGNNI_02649 2.7e-203 yvmA EGP Major facilitator Superfamily
NDOFGNNI_02650 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
NDOFGNNI_02651 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
NDOFGNNI_02652 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
NDOFGNNI_02653 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
NDOFGNNI_02654 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
NDOFGNNI_02655 3.6e-134 yvoA K transcriptional
NDOFGNNI_02656 8.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NDOFGNNI_02657 6.8e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NDOFGNNI_02658 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NDOFGNNI_02659 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NDOFGNNI_02660 1.5e-164 yvoD P COG0370 Fe2 transport system protein B
NDOFGNNI_02661 1.3e-119 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NDOFGNNI_02662 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
NDOFGNNI_02663 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
NDOFGNNI_02664 4.5e-140 yvpB NU protein conserved in bacteria
NDOFGNNI_02665 4.8e-221 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NDOFGNNI_02666 1.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NDOFGNNI_02667 6.6e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NDOFGNNI_02668 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NDOFGNNI_02669 1.7e-116 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NDOFGNNI_02670 3.1e-133 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NDOFGNNI_02671 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NDOFGNNI_02672 4.4e-112 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
NDOFGNNI_02673 2.1e-70
NDOFGNNI_02674 1e-252
NDOFGNNI_02676 0.0 msbA2 3.6.3.44 V ABC transporter
NDOFGNNI_02677 2.4e-278 S COG0457 FOG TPR repeat
NDOFGNNI_02678 1.4e-102 usp CBM50 M protein conserved in bacteria
NDOFGNNI_02679 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NDOFGNNI_02680 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NDOFGNNI_02681 5.7e-166 rapZ S Displays ATPase and GTPase activities
NDOFGNNI_02682 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NDOFGNNI_02683 1.4e-170 whiA K May be required for sporulation
NDOFGNNI_02684 1.6e-36 crh G Phosphocarrier protein Chr
NDOFGNNI_02685 8.6e-147 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
NDOFGNNI_02686 1.8e-33
NDOFGNNI_02687 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NDOFGNNI_02688 2.3e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
NDOFGNNI_02689 5.6e-141 yvcR V ABC transporter, ATP-binding protein
NDOFGNNI_02690 0.0 yxdM V ABC transporter (permease)
NDOFGNNI_02691 9.6e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NDOFGNNI_02692 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NDOFGNNI_02693 8.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
NDOFGNNI_02694 2e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
NDOFGNNI_02695 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
NDOFGNNI_02696 8.8e-173 yvdE K Transcriptional regulator
NDOFGNNI_02697 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
NDOFGNNI_02698 3.4e-233 mdxE G COG2182 Maltose-binding periplasmic proteins domains
NDOFGNNI_02699 2e-244 malC P COG1175 ABC-type sugar transport systems, permease components
NDOFGNNI_02700 1.1e-147 malD P transport
NDOFGNNI_02701 5e-154 malA S Protein of unknown function (DUF1189)
NDOFGNNI_02702 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
NDOFGNNI_02703 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
NDOFGNNI_02704 1.7e-117 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
NDOFGNNI_02705 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NDOFGNNI_02707 2.8e-182 S Patatin-like phospholipase
NDOFGNNI_02708 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
NDOFGNNI_02709 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
NDOFGNNI_02710 4.1e-50 sugE P Small Multidrug Resistance protein
NDOFGNNI_02711 1.5e-50 ykkC P Small Multidrug Resistance protein
NDOFGNNI_02712 2.6e-106 yvdT K Transcriptional regulator
NDOFGNNI_02713 3.9e-295 yveA E amino acid
NDOFGNNI_02714 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NDOFGNNI_02715 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
NDOFGNNI_02716 2.5e-261 pbpE V Beta-lactamase
NDOFGNNI_02717 1.2e-123 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NDOFGNNI_02718 8.8e-34 MA20_18690 S Protein of unknown function (DUF3237)
NDOFGNNI_02719 1.7e-92 padC Q Phenolic acid decarboxylase
NDOFGNNI_02721 6.1e-282 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
NDOFGNNI_02722 6.3e-76 slr K transcriptional
NDOFGNNI_02723 4e-122 ywqC M biosynthesis protein
NDOFGNNI_02724 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
NDOFGNNI_02725 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
NDOFGNNI_02726 3.8e-223 epsD GT4 M Glycosyl transferase 4-like
NDOFGNNI_02727 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NDOFGNNI_02728 3.2e-217 epsF GT4 M Glycosyl transferases group 1
NDOFGNNI_02729 1.4e-206 epsG S EpsG family
NDOFGNNI_02730 9.8e-194 epsH GT2 S Glycosyltransferase like family 2
NDOFGNNI_02731 4.6e-202 epsI GM pyruvyl transferase
NDOFGNNI_02732 6.6e-190 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
NDOFGNNI_02733 5.9e-256 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NDOFGNNI_02734 5.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NDOFGNNI_02735 1.3e-50 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
NDOFGNNI_02736 1.1e-222 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
NDOFGNNI_02737 2.1e-185 yvfF GM Exopolysaccharide biosynthesis protein
NDOFGNNI_02738 1e-31 yvfG S YvfG protein
NDOFGNNI_02739 6.7e-240 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NDOFGNNI_02740 2.8e-307 yvfH C L-lactate permease
NDOFGNNI_02741 1e-112 yvfI K COG2186 Transcriptional regulators
NDOFGNNI_02742 1.8e-184 lacR K Transcriptional regulator
NDOFGNNI_02743 1.1e-228 cycB G COG2182 Maltose-binding periplasmic proteins domains
NDOFGNNI_02744 4.2e-231 malC P COG1175 ABC-type sugar transport systems, permease components
NDOFGNNI_02745 7.2e-150 ganQ P transport
NDOFGNNI_02746 0.0 lacA 3.2.1.23 G beta-galactosidase
NDOFGNNI_02747 1e-248 galA 3.2.1.89 G arabinogalactan
NDOFGNNI_02748 1.6e-195 rsbU 3.1.3.3 T response regulator
NDOFGNNI_02749 1.8e-155 rsbQ S Alpha/beta hydrolase family
NDOFGNNI_02750 3e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
NDOFGNNI_02751 6.2e-134 yvfS V COG0842 ABC-type multidrug transport system, permease component
NDOFGNNI_02752 8.9e-201 desK 2.7.13.3 T Histidine kinase
NDOFGNNI_02753 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NDOFGNNI_02754 1.5e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NDOFGNNI_02755 3.5e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NDOFGNNI_02756 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NDOFGNNI_02757 4.3e-197 yvbX S Glycosyl hydrolase
NDOFGNNI_02758 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
NDOFGNNI_02759 1.6e-155 yvbV EG EamA-like transporter family
NDOFGNNI_02760 5.1e-159 yvbU K Transcriptional regulator
NDOFGNNI_02761 5.8e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NDOFGNNI_02762 5.5e-203 araR K transcriptional
NDOFGNNI_02763 1.6e-252 araE EGP Major facilitator Superfamily
NDOFGNNI_02764 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NDOFGNNI_02765 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NDOFGNNI_02766 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NDOFGNNI_02767 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NDOFGNNI_02768 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
NDOFGNNI_02769 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NDOFGNNI_02770 7.7e-82 yvbK 3.1.3.25 K acetyltransferase
NDOFGNNI_02771 0.0 tcaA S response to antibiotic
NDOFGNNI_02772 3.6e-123 exoY M Membrane
NDOFGNNI_02773 8.6e-113 yvbH S YvbH-like oligomerisation region
NDOFGNNI_02774 6.4e-103 yvbG U UPF0056 membrane protein
NDOFGNNI_02775 1.4e-98 yvbF K Belongs to the GbsR family
NDOFGNNI_02776 2.6e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NDOFGNNI_02777 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NDOFGNNI_02778 2.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NDOFGNNI_02779 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NDOFGNNI_02780 4.5e-45 sdpR K transcriptional
NDOFGNNI_02781 4.1e-94 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
NDOFGNNI_02782 4.4e-08
NDOFGNNI_02783 1.7e-171
NDOFGNNI_02784 5.1e-12 S Sporulation delaying protein SdpA
NDOFGNNI_02785 8.7e-61 yvbF K Belongs to the GbsR family
NDOFGNNI_02786 3e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NDOFGNNI_02787 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NDOFGNNI_02788 1.1e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NDOFGNNI_02789 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NDOFGNNI_02790 4.2e-226 NT chemotaxis protein
NDOFGNNI_02791 2.2e-54 yodB K transcriptional
NDOFGNNI_02792 8e-70 yvaO K Cro/C1-type HTH DNA-binding domain
NDOFGNNI_02793 4e-69 K transcriptional
NDOFGNNI_02794 7.5e-36 yvzC K Transcriptional
NDOFGNNI_02795 3.7e-153 yvaM S Serine aminopeptidase, S33
NDOFGNNI_02796 2.4e-23 secG U Preprotein translocase subunit SecG
NDOFGNNI_02797 5.6e-143 est 3.1.1.1 S Carboxylesterase
NDOFGNNI_02798 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NDOFGNNI_02799 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NDOFGNNI_02801 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NDOFGNNI_02802 4.3e-98 K Bacterial regulatory proteins, tetR family
NDOFGNNI_02803 2e-53 yvaE P Small Multidrug Resistance protein
NDOFGNNI_02804 1.3e-72 yvaD S Family of unknown function (DUF5360)
NDOFGNNI_02805 0.0 yvaC S Fusaric acid resistance protein-like
NDOFGNNI_02806 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NDOFGNNI_02807 7.6e-194 yvaA 1.1.1.371 S Oxidoreductase
NDOFGNNI_02808 2.2e-48 csoR S transcriptional
NDOFGNNI_02809 5.9e-29 copZ P Copper resistance protein CopZ
NDOFGNNI_02810 0.0 copA 3.6.3.54 P P-type ATPase
NDOFGNNI_02811 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NDOFGNNI_02812 1.6e-104 bdbD O Thioredoxin
NDOFGNNI_02813 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
NDOFGNNI_02814 4.1e-107 yvgT S membrane
NDOFGNNI_02815 0.0 helD 3.6.4.12 L DNA helicase
NDOFGNNI_02816 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NDOFGNNI_02817 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NDOFGNNI_02818 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
NDOFGNNI_02819 2.1e-85 yvgO
NDOFGNNI_02820 1.1e-155 yvgN S reductase
NDOFGNNI_02821 1.4e-119 modB P COG4149 ABC-type molybdate transport system, permease component
NDOFGNNI_02822 1.3e-134 modA P COG0725 ABC-type molybdate transport system, periplasmic component
NDOFGNNI_02823 7.5e-169 yvgK P COG1910 Periplasmic molybdate-binding protein domain
NDOFGNNI_02824 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NDOFGNNI_02825 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
NDOFGNNI_02826 6.5e-16 S Small spore protein J (Spore_SspJ)
NDOFGNNI_02827 4.9e-236 yvsH E Arginine ornithine antiporter
NDOFGNNI_02828 1.4e-178 fhuD P ABC transporter
NDOFGNNI_02829 9.3e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NDOFGNNI_02830 1.2e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NDOFGNNI_02831 1.7e-148 fhuC 3.6.3.34 HP ABC transporter
NDOFGNNI_02832 2.8e-176 M Efflux transporter rnd family, mfp subunit
NDOFGNNI_02833 1.6e-123 macB V ABC transporter, ATP-binding protein
NDOFGNNI_02834 4e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
NDOFGNNI_02835 1.3e-64 yvrL S Regulatory protein YrvL
NDOFGNNI_02836 8.1e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
NDOFGNNI_02837 2.4e-19 S YvrJ protein family
NDOFGNNI_02838 8.1e-97 yvrI K RNA polymerase
NDOFGNNI_02839 1.6e-22
NDOFGNNI_02840 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NDOFGNNI_02841 0.0 T PhoQ Sensor
NDOFGNNI_02842 1.7e-170 yvrE G SMP-30/Gluconolaconase/LRE-like region
NDOFGNNI_02843 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NDOFGNNI_02844 7.2e-167 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NDOFGNNI_02845 2.2e-185 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NDOFGNNI_02846 2.4e-245 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NDOFGNNI_02847 6.1e-100 yvqK 2.5.1.17 S Adenosyltransferase
NDOFGNNI_02848 1.4e-226 yvqJ EGP Major facilitator Superfamily
NDOFGNNI_02849 2.8e-61 liaI S membrane
NDOFGNNI_02850 3.6e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NDOFGNNI_02851 2.5e-121 liaG S Putative adhesin
NDOFGNNI_02852 5.6e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
NDOFGNNI_02853 2.7e-186 vraS 2.7.13.3 T Histidine kinase
NDOFGNNI_02854 2.4e-94 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NDOFGNNI_02855 1.4e-182 gerAC S Spore germination B3/ GerAC like, C-terminal
NDOFGNNI_02856 1.3e-196 gerAB E Spore germination protein
NDOFGNNI_02857 4.5e-245 gerAA EG Spore germination protein
NDOFGNNI_02858 3.9e-24 S Protein of unknown function (DUF3970)
NDOFGNNI_02859 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NDOFGNNI_02860 1.3e-157 yuxN K Transcriptional regulator
NDOFGNNI_02861 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
NDOFGNNI_02862 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NDOFGNNI_02863 7.8e-231 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NDOFGNNI_02864 1.2e-79 dps P Ferritin-like domain
NDOFGNNI_02865 3.8e-151 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NDOFGNNI_02866 4.2e-301 pepF2 E COG1164 Oligoendopeptidase F
NDOFGNNI_02867 9.6e-66 S YusW-like protein
NDOFGNNI_02868 1e-153 yusV 3.6.3.34 HP ABC transporter
NDOFGNNI_02869 1.1e-46 yusU S Protein of unknown function (DUF2573)
NDOFGNNI_02870 5.7e-158 yusT K LysR substrate binding domain
NDOFGNNI_02871 7.2e-106 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NDOFGNNI_02872 7.1e-65 yusQ S Tautomerase enzyme
NDOFGNNI_02873 4.2e-292 yusP P Major facilitator superfamily
NDOFGNNI_02874 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
NDOFGNNI_02875 3.2e-53 yusN M Coat F domain
NDOFGNNI_02876 5.1e-40
NDOFGNNI_02877 1.9e-164 fadM E Proline dehydrogenase
NDOFGNNI_02878 8.1e-09 S YuzL-like protein
NDOFGNNI_02879 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
NDOFGNNI_02880 7.9e-216 fadA 2.3.1.16 I Belongs to the thiolase family
NDOFGNNI_02881 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
NDOFGNNI_02882 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
NDOFGNNI_02883 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NDOFGNNI_02884 4.1e-39 yusG S Protein of unknown function (DUF2553)
NDOFGNNI_02885 1.1e-72 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
NDOFGNNI_02886 5.6e-55 traF CO Thioredoxin
NDOFGNNI_02887 2.4e-56 yusD S SCP-2 sterol transfer family
NDOFGNNI_02888 2.4e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NDOFGNNI_02889 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
NDOFGNNI_02890 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
NDOFGNNI_02891 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NDOFGNNI_02892 8.6e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NDOFGNNI_02893 4.5e-244 sufD O assembly protein SufD
NDOFGNNI_02894 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NDOFGNNI_02895 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
NDOFGNNI_02896 4.6e-271 sufB O FeS cluster assembly
NDOFGNNI_02897 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NDOFGNNI_02898 1e-41
NDOFGNNI_02900 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
NDOFGNNI_02901 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
NDOFGNNI_02902 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NDOFGNNI_02903 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
NDOFGNNI_02904 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
NDOFGNNI_02905 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
NDOFGNNI_02906 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
NDOFGNNI_02907 3.3e-135 yurK K UTRA
NDOFGNNI_02908 5.9e-205 msmX P Belongs to the ABC transporter superfamily
NDOFGNNI_02909 5e-167 bsn L Ribonuclease
NDOFGNNI_02910 6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NDOFGNNI_02911 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NDOFGNNI_02913 2.1e-185 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NDOFGNNI_02914 3.1e-110 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
NDOFGNNI_02915 1.8e-150 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NDOFGNNI_02916 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NDOFGNNI_02917 2.8e-96 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NDOFGNNI_02918 2.7e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
NDOFGNNI_02919 5.2e-281 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
NDOFGNNI_02920 4.3e-223 pbuX F xanthine
NDOFGNNI_02921 1e-230 pbuX F Permease family
NDOFGNNI_02922 8.3e-301 pucR QT COG2508 Regulator of polyketide synthase expression
NDOFGNNI_02923 4.3e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NDOFGNNI_02924 2.8e-60 yunG
NDOFGNNI_02925 4.3e-171 yunF S Protein of unknown function DUF72
NDOFGNNI_02926 2e-141 yunE S membrane transporter protein
NDOFGNNI_02927 1.2e-263 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NDOFGNNI_02928 1.1e-47 yunC S Domain of unknown function (DUF1805)
NDOFGNNI_02929 8.4e-134 yunB S Sporulation protein YunB (Spo_YunB)
NDOFGNNI_02930 4.5e-196 lytH M Peptidase, M23
NDOFGNNI_02931 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NDOFGNNI_02932 1.8e-110 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NDOFGNNI_02933 9.7e-48 yutD S protein conserved in bacteria
NDOFGNNI_02934 1e-75 yutE S Protein of unknown function DUF86
NDOFGNNI_02935 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NDOFGNNI_02936 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NDOFGNNI_02937 5e-198 yutH S Spore coat protein
NDOFGNNI_02938 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
NDOFGNNI_02939 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NDOFGNNI_02940 1.9e-172 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NDOFGNNI_02941 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
NDOFGNNI_02942 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
NDOFGNNI_02943 3.5e-57 yuzD S protein conserved in bacteria
NDOFGNNI_02944 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
NDOFGNNI_02945 3.2e-39 yuzB S Belongs to the UPF0349 family
NDOFGNNI_02946 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NDOFGNNI_02947 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NDOFGNNI_02948 3.7e-63 erpA S Belongs to the HesB IscA family
NDOFGNNI_02949 1.8e-71 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NDOFGNNI_02950 1e-116 paiB K Putative FMN-binding domain
NDOFGNNI_02951 6e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NDOFGNNI_02953 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
NDOFGNNI_02954 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
NDOFGNNI_02955 8.4e-27 yuiB S Putative membrane protein
NDOFGNNI_02956 9.5e-118 yuiC S protein conserved in bacteria
NDOFGNNI_02957 1.2e-77 yuiD S protein conserved in bacteria
NDOFGNNI_02958 8.4e-279 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NDOFGNNI_02959 8.7e-211 yuiF S antiporter
NDOFGNNI_02960 5.7e-93 bioY S Biotin biosynthesis protein
NDOFGNNI_02961 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
NDOFGNNI_02962 1.5e-166 besA S Putative esterase
NDOFGNNI_02963 3.6e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NDOFGNNI_02964 1.2e-224 entC 5.4.4.2 HQ Isochorismate synthase
NDOFGNNI_02965 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
NDOFGNNI_02966 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
NDOFGNNI_02967 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NDOFGNNI_02968 3.8e-36 mbtH S MbtH-like protein
NDOFGNNI_02969 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
NDOFGNNI_02970 1.2e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
NDOFGNNI_02971 6.5e-229 yukF QT Transcriptional regulator
NDOFGNNI_02972 2.8e-45 esxA S Belongs to the WXG100 family
NDOFGNNI_02973 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
NDOFGNNI_02974 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
NDOFGNNI_02975 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NDOFGNNI_02976 0.0 esaA S type VII secretion protein EsaA
NDOFGNNI_02977 4.7e-63 yueC S Family of unknown function (DUF5383)
NDOFGNNI_02978 4.9e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NDOFGNNI_02979 4.8e-96 yueE S phosphohydrolase
NDOFGNNI_02980 2.9e-24 S Protein of unknown function (DUF2642)
NDOFGNNI_02981 3.8e-66 S Protein of unknown function (DUF2283)
NDOFGNNI_02982 6e-189 yueF S transporter activity
NDOFGNNI_02983 2.1e-32 yueG S Spore germination protein gerPA/gerPF
NDOFGNNI_02984 2.8e-38 yueH S YueH-like protein
NDOFGNNI_02985 7.9e-67 yueI S Protein of unknown function (DUF1694)
NDOFGNNI_02986 9.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
NDOFGNNI_02987 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NDOFGNNI_02988 3.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
NDOFGNNI_02989 1.1e-22 yuzC
NDOFGNNI_02991 7.5e-140 comQ H Belongs to the FPP GGPP synthase family
NDOFGNNI_02993 7.1e-269 comP 2.7.13.3 T Histidine kinase
NDOFGNNI_02994 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NDOFGNNI_02995 9.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
NDOFGNNI_02996 5.7e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
NDOFGNNI_02997 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NDOFGNNI_02998 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NDOFGNNI_02999 5.4e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NDOFGNNI_03000 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NDOFGNNI_03001 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NDOFGNNI_03002 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NDOFGNNI_03003 5.5e-14
NDOFGNNI_03004 2.8e-233 maeN C COG3493 Na citrate symporter
NDOFGNNI_03005 5e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
NDOFGNNI_03006 1.9e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
NDOFGNNI_03007 3.2e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NDOFGNNI_03008 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
NDOFGNNI_03009 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
NDOFGNNI_03010 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NDOFGNNI_03011 6.3e-78 yufK S Family of unknown function (DUF5366)
NDOFGNNI_03012 1.8e-74 yuxK S protein conserved in bacteria
NDOFGNNI_03013 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
NDOFGNNI_03014 3.8e-185 yuxJ EGP Major facilitator Superfamily
NDOFGNNI_03016 1.9e-115 kapD L the KinA pathway to sporulation
NDOFGNNI_03017 7.4e-70 kapB G Kinase associated protein B
NDOFGNNI_03018 4.6e-233 T PhoQ Sensor
NDOFGNNI_03019 2.4e-225 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NDOFGNNI_03020 4.6e-39 yugE S Domain of unknown function (DUF1871)
NDOFGNNI_03021 1e-156 yugF I Hydrolase
NDOFGNNI_03022 1.6e-85 alaR K Transcriptional regulator
NDOFGNNI_03023 4.8e-199 yugH 2.6.1.1 E Aminotransferase
NDOFGNNI_03024 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
NDOFGNNI_03025 1.1e-34 yuzA S Domain of unknown function (DUF378)
NDOFGNNI_03026 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
NDOFGNNI_03027 1.1e-228 yugK C Dehydrogenase
NDOFGNNI_03028 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
NDOFGNNI_03030 1.3e-72 yugN S YugN-like family
NDOFGNNI_03031 1.1e-181 yugO P COG1226 Kef-type K transport systems
NDOFGNNI_03032 5.4e-53 mstX S Membrane-integrating protein Mistic
NDOFGNNI_03033 1.1e-35
NDOFGNNI_03034 1.4e-116 yugP S Zn-dependent protease
NDOFGNNI_03035 2.9e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
NDOFGNNI_03036 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
NDOFGNNI_03037 2.1e-72 yugU S Uncharacterised protein family UPF0047
NDOFGNNI_03038 2.3e-35
NDOFGNNI_03039 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
NDOFGNNI_03040 3.2e-225 mcpA NT chemotaxis protein
NDOFGNNI_03041 6.9e-220 mcpA NT chemotaxis protein
NDOFGNNI_03042 3.2e-294 mcpA NT chemotaxis protein
NDOFGNNI_03043 2.1e-237 mcpA NT chemotaxis protein
NDOFGNNI_03044 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
NDOFGNNI_03045 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
NDOFGNNI_03046 2.2e-271 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NDOFGNNI_03047 7.2e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
NDOFGNNI_03048 2.6e-252 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
NDOFGNNI_03049 3.3e-183 ygjR S Oxidoreductase
NDOFGNNI_03050 3.7e-189 yubA S transporter activity
NDOFGNNI_03051 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NDOFGNNI_03053 1.1e-86 cdoA 1.13.11.20 S Cysteine dioxygenase type I
NDOFGNNI_03054 1e-157 yubD P Major Facilitator Superfamily
NDOFGNNI_03055 1.8e-105 yubD P Major Facilitator Superfamily
NDOFGNNI_03056 3.2e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NDOFGNNI_03057 1e-38 yiaA S yiaA/B two helix domain
NDOFGNNI_03058 4.6e-236 ktrB P Potassium
NDOFGNNI_03059 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
NDOFGNNI_03060 2.2e-91 yuaB
NDOFGNNI_03061 5.5e-95 yuaC K Belongs to the GbsR family
NDOFGNNI_03062 6.8e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
NDOFGNNI_03063 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
NDOFGNNI_03064 7.9e-108 yuaD
NDOFGNNI_03065 3.9e-84 yuaE S DinB superfamily
NDOFGNNI_03066 1e-74 yuaF OU Membrane protein implicated in regulation of membrane protease activity
NDOFGNNI_03067 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
NDOFGNNI_03068 2.2e-93 M1-753 M FR47-like protein
NDOFGNNI_03069 4.1e-88 thiT S Thiamine transporter protein (Thia_YuaJ)
NDOFGNNI_03072 1.8e-156 ydhU P Catalase
NDOFGNNI_03073 3.5e-210 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
NDOFGNNI_03074 4e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
NDOFGNNI_03075 1.5e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
NDOFGNNI_03076 1.1e-132 ydhQ K UTRA
NDOFGNNI_03077 2.4e-288 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NDOFGNNI_03078 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NDOFGNNI_03079 3.5e-52 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
NDOFGNNI_03080 1.1e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
NDOFGNNI_03081 4.6e-200 pbuE EGP Major facilitator Superfamily
NDOFGNNI_03082 2.5e-98 ydhK M Protein of unknown function (DUF1541)
NDOFGNNI_03083 2.5e-183 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NDOFGNNI_03084 1.6e-85 K Acetyltransferase (GNAT) domain
NDOFGNNI_03086 4.3e-67 frataxin S Domain of unknown function (DU1801)
NDOFGNNI_03087 1.4e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NDOFGNNI_03088 1.9e-127
NDOFGNNI_03089 9.1e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NDOFGNNI_03090 3.3e-244 ydhD M Glycosyl hydrolase
NDOFGNNI_03091 5.5e-121 ydhC K FCD
NDOFGNNI_03092 1.2e-121 ydhB S membrane transporter protein
NDOFGNNI_03093 7.4e-209 tcaB EGP Major facilitator Superfamily
NDOFGNNI_03094 2.4e-69 ydgJ K Winged helix DNA-binding domain
NDOFGNNI_03095 1e-113 drgA C nitroreductase
NDOFGNNI_03096 0.0 ydgH S drug exporters of the RND superfamily
NDOFGNNI_03097 1.4e-78 K helix_turn_helix multiple antibiotic resistance protein
NDOFGNNI_03098 1.7e-90 dinB S DinB family
NDOFGNNI_03099 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NDOFGNNI_03100 1.2e-297 expZ S ABC transporter
NDOFGNNI_03101 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
NDOFGNNI_03102 7.3e-53 S DoxX-like family
NDOFGNNI_03103 1.5e-101 K Bacterial regulatory proteins, tetR family
NDOFGNNI_03104 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
NDOFGNNI_03105 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
NDOFGNNI_03106 2.2e-75 cotP O Belongs to the small heat shock protein (HSP20) family
NDOFGNNI_03107 5.2e-122 ydfS S Protein of unknown function (DUF421)
NDOFGNNI_03108 4.4e-118 ydfR S Protein of unknown function (DUF421)
NDOFGNNI_03110 6.3e-29
NDOFGNNI_03111 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
NDOFGNNI_03112 1.3e-57 traF CO Thioredoxin
NDOFGNNI_03113 8.8e-63 mhqP S DoxX
NDOFGNNI_03114 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
NDOFGNNI_03115 9.6e-112 ydfN C nitroreductase
NDOFGNNI_03116 7.8e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NDOFGNNI_03117 6.6e-145 K Bacterial transcription activator, effector binding domain
NDOFGNNI_03118 8.5e-117 S Protein of unknown function (DUF554)
NDOFGNNI_03119 3.1e-175 S Alpha/beta hydrolase family
NDOFGNNI_03120 0.0 ydfJ S drug exporters of the RND superfamily
NDOFGNNI_03121 9.3e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NDOFGNNI_03122 8.8e-175 ydfH 2.7.13.3 T Histidine kinase
NDOFGNNI_03124 1e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NDOFGNNI_03125 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
NDOFGNNI_03126 7.2e-115 ydfE S Flavin reductase like domain
NDOFGNNI_03127 2.3e-273 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NDOFGNNI_03128 4.4e-161 ydfC EG EamA-like transporter family
NDOFGNNI_03129 1.8e-147 ydfB J GNAT acetyltransferase
NDOFGNNI_03130 2.6e-231 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NDOFGNNI_03131 6.3e-57 arsR K transcriptional
NDOFGNNI_03132 2.1e-103 ydeS K Transcriptional regulator
NDOFGNNI_03133 1.1e-191 ydeR EGP Major facilitator Superfamily
NDOFGNNI_03134 1.3e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NDOFGNNI_03135 5.2e-56 K HxlR-like helix-turn-helix
NDOFGNNI_03136 4.7e-105 ydeN S Serine hydrolase
NDOFGNNI_03137 2.1e-73 maoC I N-terminal half of MaoC dehydratase
NDOFGNNI_03138 6.4e-273 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NDOFGNNI_03139 4.1e-153 ydeK EG -transporter
NDOFGNNI_03140 8.8e-85 K Transcriptional regulator C-terminal region
NDOFGNNI_03141 8.3e-15 ptsH G PTS HPr component phosphorylation site
NDOFGNNI_03142 1.1e-31 S SNARE associated Golgi protein
NDOFGNNI_03143 1.1e-97
NDOFGNNI_03144 3.2e-104 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
NDOFGNNI_03145 2.7e-45 ydeH
NDOFGNNI_03146 7.9e-217 ydeG EGP Major facilitator superfamily
NDOFGNNI_03147 4.3e-261 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NDOFGNNI_03148 1e-39 ydeE K AraC family transcriptional regulator
NDOFGNNI_03149 3.7e-90 ydeE K AraC family transcriptional regulator
NDOFGNNI_03150 8.3e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NDOFGNNI_03151 1.1e-161 rhaS5 K AraC-like ligand binding domain
NDOFGNNI_03152 9.8e-139 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NDOFGNNI_03153 2.3e-78 carD K Transcription factor
NDOFGNNI_03154 8.7e-30 cspL K Cold shock
NDOFGNNI_03155 5.4e-192 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NDOFGNNI_03156 4.6e-42
NDOFGNNI_03157 2.8e-33 K Helix-turn-helix XRE-family like proteins
NDOFGNNI_03158 1.4e-48 M nucleic acid phosphodiester bond hydrolysis
NDOFGNNI_03159 2.4e-83 UW nuclease activity
NDOFGNNI_03160 3.2e-44
NDOFGNNI_03161 1.7e-75 rimJ2 J Acetyltransferase (GNAT) domain
NDOFGNNI_03169 1.6e-84 ydcK S Belongs to the SprT family
NDOFGNNI_03170 0.0 yhgF K COG2183 Transcriptional accessory protein
NDOFGNNI_03171 1.6e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
NDOFGNNI_03172 1.5e-82 ydcG S EVE domain
NDOFGNNI_03176 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
NDOFGNNI_03177 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NDOFGNNI_03178 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NDOFGNNI_03179 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
NDOFGNNI_03180 7.1e-189 rsbU 3.1.3.3 KT phosphatase
NDOFGNNI_03181 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NDOFGNNI_03182 5.2e-57 rsbS T antagonist
NDOFGNNI_03183 1.3e-143 rsbR T Positive regulator of sigma-B
NDOFGNNI_03184 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
NDOFGNNI_03185 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NDOFGNNI_03186 2.1e-221 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NDOFGNNI_03187 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
NDOFGNNI_03188 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NDOFGNNI_03189 2.2e-105 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
NDOFGNNI_03190 1.1e-259 ydbT S Membrane
NDOFGNNI_03191 2.1e-82 ydbS S Bacterial PH domain
NDOFGNNI_03192 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NDOFGNNI_03193 6.9e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NDOFGNNI_03194 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NDOFGNNI_03195 4.3e-55 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NDOFGNNI_03196 9.6e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NDOFGNNI_03197 2.2e-07 S Fur-regulated basic protein A
NDOFGNNI_03198 1.1e-18 S Fur-regulated basic protein B
NDOFGNNI_03199 1.4e-217 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
NDOFGNNI_03200 2.7e-52 ydbL
NDOFGNNI_03201 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NDOFGNNI_03202 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
NDOFGNNI_03203 9.7e-181 ydbI S AI-2E family transporter
NDOFGNNI_03204 5.3e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NDOFGNNI_03205 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
NDOFGNNI_03206 4.8e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NDOFGNNI_03207 5.1e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NDOFGNNI_03208 1.3e-153 ydbD P Catalase
NDOFGNNI_03209 3.1e-62 ydbC S Domain of unknown function (DUF4937
NDOFGNNI_03210 8.9e-59 ydbB G Cupin domain
NDOFGNNI_03212 2.4e-147 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
NDOFGNNI_03213 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
NDOFGNNI_03215 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
NDOFGNNI_03216 2.1e-39
NDOFGNNI_03217 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NDOFGNNI_03218 8.5e-79 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NDOFGNNI_03219 0.0 ydaO E amino acid
NDOFGNNI_03220 0.0 ydaN S Bacterial cellulose synthase subunit
NDOFGNNI_03221 4.5e-233 ydaM M Glycosyl transferase family group 2
NDOFGNNI_03222 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
NDOFGNNI_03223 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
NDOFGNNI_03224 1.9e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
NDOFGNNI_03225 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NDOFGNNI_03226 2.5e-74 lrpC K Transcriptional regulator
NDOFGNNI_03227 3.3e-46 ydzA EGP Major facilitator Superfamily
NDOFGNNI_03228 1e-137 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NDOFGNNI_03229 6.8e-77 ydaG 1.4.3.5 S general stress protein
NDOFGNNI_03230 6.4e-99 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NDOFGNNI_03231 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
NDOFGNNI_03232 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NDOFGNNI_03233 9e-99 ydaC Q Methyltransferase domain
NDOFGNNI_03234 2.1e-293 ydaB IQ acyl-CoA ligase
NDOFGNNI_03235 0.0 mtlR K transcriptional regulator, MtlR
NDOFGNNI_03236 2.8e-176 ydhF S Oxidoreductase
NDOFGNNI_03237 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
NDOFGNNI_03238 1.4e-49 yczJ S biosynthesis
NDOFGNNI_03240 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
NDOFGNNI_03241 1.2e-132 kipR K Transcriptional regulator
NDOFGNNI_03242 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
NDOFGNNI_03243 1.4e-133 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
NDOFGNNI_03244 2.8e-148 ycsI S Belongs to the D-glutamate cyclase family
NDOFGNNI_03245 1.6e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
NDOFGNNI_03246 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
NDOFGNNI_03247 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NDOFGNNI_03249 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
NDOFGNNI_03250 1.9e-112 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
NDOFGNNI_03251 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NDOFGNNI_03252 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NDOFGNNI_03253 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
NDOFGNNI_03254 1.3e-210 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
NDOFGNNI_03255 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NDOFGNNI_03256 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
NDOFGNNI_03257 7.3e-56
NDOFGNNI_03258 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
NDOFGNNI_03259 4.2e-308 ycnJ P protein, homolog of Cu resistance protein CopC
NDOFGNNI_03260 2.9e-100 ycnI S protein conserved in bacteria
NDOFGNNI_03261 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NDOFGNNI_03262 1.8e-148 glcU U Glucose uptake
NDOFGNNI_03263 3.8e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NDOFGNNI_03264 2.4e-245 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NDOFGNNI_03265 6.6e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NDOFGNNI_03266 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
NDOFGNNI_03267 1.6e-45 ycnE S Monooxygenase
NDOFGNNI_03268 2.2e-134 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
NDOFGNNI_03269 2.7e-152 ycnC K Transcriptional regulator
NDOFGNNI_03270 3.2e-251 ycnB EGP Major facilitator Superfamily
NDOFGNNI_03271 9.4e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
NDOFGNNI_03272 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
NDOFGNNI_03273 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NDOFGNNI_03274 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NDOFGNNI_03275 1.5e-250 lysC 2.7.2.4 E Belongs to the aspartokinase family
NDOFGNNI_03278 2e-70 S aspartate phosphatase
NDOFGNNI_03279 1.1e-259 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NDOFGNNI_03280 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NDOFGNNI_03281 1.3e-202 yclI V ABC transporter (permease) YclI
NDOFGNNI_03282 7.3e-121 yclH P ABC transporter
NDOFGNNI_03283 6e-197 gerKB F Spore germination protein
NDOFGNNI_03284 4.1e-231 gerKC S spore germination
NDOFGNNI_03285 5.4e-279 gerKA EG Spore germination protein
NDOFGNNI_03287 7.7e-308 yclG M Pectate lyase superfamily protein
NDOFGNNI_03288 1.5e-267 dtpT E amino acid peptide transporter
NDOFGNNI_03289 1e-156 yclE 3.4.11.5 S Alpha beta hydrolase
NDOFGNNI_03290 3.3e-80 yclD
NDOFGNNI_03291 4e-39 bsdD 4.1.1.61 S response to toxic substance
NDOFGNNI_03292 9.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NDOFGNNI_03293 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NDOFGNNI_03294 1.9e-161 bsdA K LysR substrate binding domain
NDOFGNNI_03295 3.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NDOFGNNI_03296 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
NDOFGNNI_03297 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NDOFGNNI_03298 1.7e-114 yczE S membrane
NDOFGNNI_03299 9.5e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
NDOFGNNI_03300 9.2e-253 ycxD K GntR family transcriptional regulator
NDOFGNNI_03301 3.4e-161 ycxC EG EamA-like transporter family
NDOFGNNI_03302 2.4e-90 S YcxB-like protein
NDOFGNNI_03303 4.8e-224 EGP Major Facilitator Superfamily
NDOFGNNI_03304 5.7e-140 srfAD Q thioesterase
NDOFGNNI_03305 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
NDOFGNNI_03306 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NDOFGNNI_03307 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NDOFGNNI_03308 1.3e-63 hxlR K transcriptional
NDOFGNNI_03309 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
NDOFGNNI_03310 1.1e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
NDOFGNNI_03311 9.6e-186 tlpC 2.7.13.3 NT chemotaxis protein
NDOFGNNI_03312 3.5e-71 nucA M Deoxyribonuclease NucA/NucB
NDOFGNNI_03313 1.1e-68 nin S Competence protein J (ComJ)
NDOFGNNI_03314 1.2e-293 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NDOFGNNI_03315 2.3e-51 yckD S Protein of unknown function (DUF2680)
NDOFGNNI_03316 3.8e-49 yckC S membrane
NDOFGNNI_03318 1.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
NDOFGNNI_03319 5.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
NDOFGNNI_03320 7e-228 yciC S GTPases (G3E family)
NDOFGNNI_03321 2.7e-108 yciB M ErfK YbiS YcfS YnhG
NDOFGNNI_03322 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
NDOFGNNI_03323 3.8e-221 nasA P COG2223 Nitrate nitrite transporter
NDOFGNNI_03324 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
NDOFGNNI_03325 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NDOFGNNI_03326 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NDOFGNNI_03327 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
NDOFGNNI_03328 2.7e-274 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NDOFGNNI_03329 6.9e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NDOFGNNI_03330 2.6e-160 I alpha/beta hydrolase fold
NDOFGNNI_03331 1.2e-139 ycgR S permeases
NDOFGNNI_03332 2.2e-146 ycgQ S membrane
NDOFGNNI_03333 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
NDOFGNNI_03334 5.9e-247 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NDOFGNNI_03335 8.1e-293 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NDOFGNNI_03336 5.1e-170 ycgM E Proline dehydrogenase
NDOFGNNI_03337 2.4e-144 ycgL S Predicted nucleotidyltransferase
NDOFGNNI_03338 8e-182 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
NDOFGNNI_03339 3.2e-178 oxyR3 K LysR substrate binding domain
NDOFGNNI_03340 1.3e-142 yafE Q ubiE/COQ5 methyltransferase family
NDOFGNNI_03341 1.5e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NDOFGNNI_03342 4.7e-108 tmrB S AAA domain
NDOFGNNI_03343 4.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NDOFGNNI_03344 2.4e-112 ycgI S Domain of unknown function (DUF1989)
NDOFGNNI_03345 1.6e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
NDOFGNNI_03346 1.2e-151 yqcI S YqcI/YcgG family
NDOFGNNI_03347 6.8e-113 ycgF E Lysine exporter protein LysE YggA
NDOFGNNI_03348 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
NDOFGNNI_03349 6.6e-263 mdr EGP Major facilitator Superfamily
NDOFGNNI_03350 2.5e-292 lctP C L-lactate permease
NDOFGNNI_03351 7.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NDOFGNNI_03352 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
NDOFGNNI_03353 4.1e-81 ycgB
NDOFGNNI_03354 2.4e-139 ycgA S Membrane
NDOFGNNI_03355 3.4e-80 ycgA S Membrane
NDOFGNNI_03356 4.1e-217 amhX S amidohydrolase
NDOFGNNI_03357 5.3e-164 opuAC E glycine betaine
NDOFGNNI_03358 1.3e-127 opuAB P glycine betaine
NDOFGNNI_03359 4.3e-228 proV 3.6.3.32 E glycine betaine
NDOFGNNI_03360 6.1e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
NDOFGNNI_03361 2.6e-206 yceJ EGP Uncharacterised MFS-type transporter YbfB
NDOFGNNI_03362 8.7e-218 naiP P Uncharacterised MFS-type transporter YbfB
NDOFGNNI_03363 2e-192 yceH P Belongs to the TelA family
NDOFGNNI_03364 0.0 yceG S Putative component of 'biosynthetic module'
NDOFGNNI_03365 6.3e-137 terC P Protein of unknown function (DUF475)
NDOFGNNI_03366 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
NDOFGNNI_03367 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
NDOFGNNI_03368 1.9e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
NDOFGNNI_03369 8.9e-184 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NDOFGNNI_03370 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NDOFGNNI_03371 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NDOFGNNI_03372 1.2e-166 adcA P Belongs to the bacterial solute-binding protein 9 family
NDOFGNNI_03373 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
NDOFGNNI_03374 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
NDOFGNNI_03375 1.2e-173 S response regulator aspartate phosphatase
NDOFGNNI_03376 7.3e-94 cwlK M D-alanyl-D-alanine carboxypeptidase
NDOFGNNI_03377 5.1e-260 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
NDOFGNNI_03378 2.3e-278 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
NDOFGNNI_03379 6.6e-177 ycdA S Domain of unknown function (DUF5105)
NDOFGNNI_03380 1.3e-173 yccK C Aldo keto reductase
NDOFGNNI_03381 3.2e-201 natB CP ABC-2 family transporter protein
NDOFGNNI_03382 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
NDOFGNNI_03383 1.2e-126 lytR_2 T LytTr DNA-binding domain
NDOFGNNI_03384 2.9e-160 2.7.13.3 T GHKL domain
NDOFGNNI_03385 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
NDOFGNNI_03386 4.5e-59 S RDD family
NDOFGNNI_03387 6.2e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NDOFGNNI_03388 2.6e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NDOFGNNI_03389 7e-101 yxaF K Transcriptional regulator
NDOFGNNI_03390 6.5e-228 lmrB EGP the major facilitator superfamily
NDOFGNNI_03391 5.2e-201 ycbU E Selenocysteine lyase
NDOFGNNI_03392 4.5e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NDOFGNNI_03393 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NDOFGNNI_03394 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NDOFGNNI_03395 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
NDOFGNNI_03396 6.6e-136 ycbR T vWA found in TerF C terminus
NDOFGNNI_03397 1.3e-78 sleB 3.5.1.28 M Cell wall
NDOFGNNI_03398 8.2e-53 ycbP S Protein of unknown function (DUF2512)
NDOFGNNI_03399 2.1e-115 S ABC-2 family transporter protein
NDOFGNNI_03400 1.1e-167 ycbN V ABC transporter, ATP-binding protein
NDOFGNNI_03401 2.4e-170 T PhoQ Sensor
NDOFGNNI_03402 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NDOFGNNI_03403 7.3e-172 eamA1 EG spore germination
NDOFGNNI_03404 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
NDOFGNNI_03405 1.8e-178 ycbJ S Macrolide 2'-phosphotransferase
NDOFGNNI_03406 3.7e-298 garD 4.2.1.42, 4.2.1.7 G Altronate
NDOFGNNI_03407 1.5e-124 ycbG K FCD
NDOFGNNI_03408 2.2e-270 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NDOFGNNI_03409 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
NDOFGNNI_03410 4.5e-272 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NDOFGNNI_03411 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
NDOFGNNI_03412 9e-170 glnL T Regulator
NDOFGNNI_03413 4.2e-229 phoQ 2.7.13.3 T Histidine kinase
NDOFGNNI_03414 1.1e-186 glsA 3.5.1.2 E Belongs to the glutaminase family
NDOFGNNI_03415 1.3e-255 agcS E Sodium alanine symporter
NDOFGNNI_03416 1e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
NDOFGNNI_03417 4.1e-259 mmuP E amino acid
NDOFGNNI_03418 1.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NDOFGNNI_03420 4.9e-128 K UTRA
NDOFGNNI_03421 2e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NDOFGNNI_03422 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NDOFGNNI_03423 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NDOFGNNI_03424 3.9e-192 yceA S Belongs to the UPF0176 family
NDOFGNNI_03425 3.6e-249 S Erythromycin esterase
NDOFGNNI_03426 4.6e-45 ybfN
NDOFGNNI_03427 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NDOFGNNI_03428 2.7e-85 ybfM S SNARE associated Golgi protein
NDOFGNNI_03429 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NDOFGNNI_03430 8e-168 S Alpha/beta hydrolase family
NDOFGNNI_03432 1.5e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
NDOFGNNI_03433 2.3e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NDOFGNNI_03434 2.8e-143 msmR K AraC-like ligand binding domain
NDOFGNNI_03435 5.7e-161 ybfH EG EamA-like transporter family
NDOFGNNI_03436 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
NDOFGNNI_03438 3.5e-222 ybfB G COG0477 Permeases of the major facilitator superfamily
NDOFGNNI_03439 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
NDOFGNNI_03440 2.9e-35 S Protein of unknown function (DUF2651)
NDOFGNNI_03441 7.3e-258 glpT G -transporter
NDOFGNNI_03442 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NDOFGNNI_03443 3.3e-289 ybeC E amino acid
NDOFGNNI_03444 4.9e-41 ybyB
NDOFGNNI_03445 7.6e-241 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
NDOFGNNI_03446 1.8e-150 ybxI 3.5.2.6 V beta-lactamase
NDOFGNNI_03447 4.9e-30 ybxH S Family of unknown function (DUF5370)
NDOFGNNI_03448 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
NDOFGNNI_03449 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
NDOFGNNI_03450 1.5e-214 ybdO S Domain of unknown function (DUF4885)
NDOFGNNI_03451 1.7e-151 ybdN
NDOFGNNI_03452 3.9e-139 KLT Protein tyrosine kinase
NDOFGNNI_03454 1.8e-168 T His Kinase A (phospho-acceptor) domain
NDOFGNNI_03455 3.8e-122 T Transcriptional regulatory protein, C terminal
NDOFGNNI_03456 1.4e-181 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NDOFGNNI_03457 9.6e-79 txn CO Thioredoxin-like
NDOFGNNI_03458 7.8e-91 C HEAT repeats
NDOFGNNI_03459 1.2e-247 skfF S ABC transporter
NDOFGNNI_03460 1.9e-135 skfE V ABC transporter
NDOFGNNI_03461 1.6e-277 V CAAX protease self-immunity
NDOFGNNI_03462 9.1e-239 J 4Fe-4S single cluster domain
NDOFGNNI_03464 3.5e-203 ybcL EGP Major facilitator Superfamily
NDOFGNNI_03465 5.1e-50 ybzH K Helix-turn-helix domain
NDOFGNNI_03466 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
NDOFGNNI_03467 3.9e-47
NDOFGNNI_03468 3.2e-92 can 4.2.1.1 P carbonic anhydrase
NDOFGNNI_03469 0.0 ybcC S Belongs to the UPF0753 family
NDOFGNNI_03470 4.8e-274 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NDOFGNNI_03471 9.6e-100 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NDOFGNNI_03472 8.3e-119 adaA 3.2.2.21 K Transcriptional regulator
NDOFGNNI_03473 8.1e-176 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NDOFGNNI_03474 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NDOFGNNI_03475 1.8e-251 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NDOFGNNI_03476 4.4e-224 ybbR S protein conserved in bacteria
NDOFGNNI_03477 2.3e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NDOFGNNI_03478 1.8e-102 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NDOFGNNI_03479 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
NDOFGNNI_03485 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
NDOFGNNI_03486 1.6e-85 ybbJ J acetyltransferase
NDOFGNNI_03487 3e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NDOFGNNI_03488 2.5e-150 ybbH K transcriptional
NDOFGNNI_03489 3.7e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NDOFGNNI_03490 1.1e-250 yfeW 3.4.16.4 V Belongs to the UPF0214 family
NDOFGNNI_03491 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
NDOFGNNI_03492 5.4e-239 ybbC 3.2.1.52 S protein conserved in bacteria
NDOFGNNI_03493 2.9e-306 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
NDOFGNNI_03494 2.7e-166 feuA P Iron-uptake system-binding protein
NDOFGNNI_03495 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NDOFGNNI_03496 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NDOFGNNI_03497 2.2e-142 ybbA S Putative esterase
NDOFGNNI_03498 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
NDOFGNNI_03500 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
NDOFGNNI_03501 6.7e-167 ygxA S Nucleotidyltransferase-like
NDOFGNNI_03502 9.5e-56 ygzB S UPF0295 protein
NDOFGNNI_03503 4e-80 perR P Belongs to the Fur family
NDOFGNNI_03504 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
NDOFGNNI_03505 8.1e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NDOFGNNI_03506 8.7e-180 ygaE S Membrane
NDOFGNNI_03507 1.2e-300 ygaD V ABC transporter
NDOFGNNI_03508 1.3e-104 ygaC J Belongs to the UPF0374 family
NDOFGNNI_03509 1.5e-37 ygaB S YgaB-like protein
NDOFGNNI_03510 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
NDOFGNNI_03511 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NDOFGNNI_03512 6.9e-36 yfhS
NDOFGNNI_03513 3.3e-210 mutY L A G-specific
NDOFGNNI_03514 1.2e-185 yfhP S membrane-bound metal-dependent
NDOFGNNI_03515 0.0 yfhO S Bacterial membrane protein YfhO
NDOFGNNI_03516 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NDOFGNNI_03517 1.3e-170 yfhM S Alpha beta hydrolase
NDOFGNNI_03518 3.9e-50 yfhL S SdpI/YhfL protein family
NDOFGNNI_03519 2.4e-87 batE T Bacterial SH3 domain homologues
NDOFGNNI_03520 2.9e-44 yfhJ S WVELL protein
NDOFGNNI_03521 6.2e-20 sspK S reproduction
NDOFGNNI_03522 4.3e-209 yfhI EGP Major facilitator Superfamily
NDOFGNNI_03524 9.7e-52 yfhH S Protein of unknown function (DUF1811)
NDOFGNNI_03525 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
NDOFGNNI_03526 1.6e-171 yfhF S nucleoside-diphosphate sugar epimerase
NDOFGNNI_03528 2.1e-25 yfhD S YfhD-like protein
NDOFGNNI_03529 3.9e-107 yfhC C nitroreductase
NDOFGNNI_03530 1.6e-165 yfhB 5.3.3.17 S PhzF family
NDOFGNNI_03531 6.8e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NDOFGNNI_03532 7.6e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NDOFGNNI_03533 5.7e-175 yfiY P ABC transporter substrate-binding protein
NDOFGNNI_03534 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NDOFGNNI_03535 5.8e-80 yfiV K transcriptional
NDOFGNNI_03536 3.2e-281 yfiU EGP Major facilitator Superfamily
NDOFGNNI_03537 3.1e-98 yfiT S Belongs to the metal hydrolase YfiT family
NDOFGNNI_03538 1.5e-212 yfiS EGP Major facilitator Superfamily
NDOFGNNI_03539 2e-109 yfiR K Transcriptional regulator
NDOFGNNI_03540 9e-198 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NDOFGNNI_03541 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NDOFGNNI_03542 8.3e-99 padR K transcriptional
NDOFGNNI_03543 4.6e-208 V COG0842 ABC-type multidrug transport system, permease component
NDOFGNNI_03544 1.3e-213 V ABC-2 family transporter protein
NDOFGNNI_03545 6.2e-171 V ABC transporter, ATP-binding protein
NDOFGNNI_03546 3.2e-113 KT LuxR family transcriptional regulator
NDOFGNNI_03547 1.1e-214 yxjM T Histidine kinase
NDOFGNNI_03549 1.1e-233 S Oxidoreductase
NDOFGNNI_03550 8.4e-184 G Xylose isomerase
NDOFGNNI_03551 1.8e-262 iolT EGP Major facilitator Superfamily
NDOFGNNI_03552 1.5e-177 K AraC-like ligand binding domain
NDOFGNNI_03553 5.7e-163 yfiE 1.13.11.2 S glyoxalase
NDOFGNNI_03554 9.8e-65 mhqP S DoxX
NDOFGNNI_03555 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
NDOFGNNI_03556 2.1e-310 yfiB3 V ABC transporter
NDOFGNNI_03557 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NDOFGNNI_03558 3.2e-141 glvR K Helix-turn-helix domain, rpiR family
NDOFGNNI_03559 9.9e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NDOFGNNI_03560 1.1e-44 yfjA S Belongs to the WXG100 family
NDOFGNNI_03561 9.2e-191 yfjB
NDOFGNNI_03562 4.1e-144 yfjC
NDOFGNNI_03563 1.8e-101 yfjD S Family of unknown function (DUF5381)
NDOFGNNI_03564 1.3e-80 S Family of unknown function (DUF5381)
NDOFGNNI_03565 4e-56 yfjF S UPF0060 membrane protein
NDOFGNNI_03566 1.2e-25 sspH S Belongs to the SspH family
NDOFGNNI_03567 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
NDOFGNNI_03568 2.4e-256 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NDOFGNNI_03569 2.9e-197 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NDOFGNNI_03570 1e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NDOFGNNI_03571 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NDOFGNNI_03572 3e-29 yfjL
NDOFGNNI_03573 1.1e-83 yfjM S Psort location Cytoplasmic, score
NDOFGNNI_03574 1.1e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NDOFGNNI_03575 1.6e-39 S YfzA-like protein
NDOFGNNI_03576 4e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NDOFGNNI_03577 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NDOFGNNI_03578 1.7e-184 corA P Mediates influx of magnesium ions
NDOFGNNI_03579 1.8e-148 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NDOFGNNI_03580 1.7e-153 pdaA G deacetylase
NDOFGNNI_03581 1.1e-26 yfjT
NDOFGNNI_03582 5.4e-222 yfkA S YfkB-like domain
NDOFGNNI_03583 6.6e-148 yfkC M Mechanosensitive ion channel
NDOFGNNI_03584 1.2e-146 yfkD S YfkD-like protein
NDOFGNNI_03585 1.8e-182 cax P COG0387 Ca2 H antiporter
NDOFGNNI_03586 3.4e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
NDOFGNNI_03587 5e-08
NDOFGNNI_03588 8.2e-143 yihY S Belongs to the UPF0761 family
NDOFGNNI_03589 2.4e-50 yfkI S gas vesicle protein
NDOFGNNI_03590 1e-81 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NDOFGNNI_03591 2.1e-29 yfkK S Belongs to the UPF0435 family
NDOFGNNI_03592 8.9e-207 ydiM EGP Major facilitator Superfamily
NDOFGNNI_03593 3.6e-88 yfkM 1.11.1.6, 3.5.1.124 S protease
NDOFGNNI_03594 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NDOFGNNI_03595 1.1e-124 yfkO C nitroreductase
NDOFGNNI_03596 1.8e-133 treR K transcriptional
NDOFGNNI_03597 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NDOFGNNI_03598 2.5e-256 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NDOFGNNI_03599 4.1e-281 yfkQ EG Spore germination protein
NDOFGNNI_03600 5.1e-207 yfkR S spore germination
NDOFGNNI_03602 1.3e-193 E Spore germination protein
NDOFGNNI_03603 2.2e-252 agcS_1 E Sodium alanine symporter
NDOFGNNI_03604 2.5e-62 yhdN S Domain of unknown function (DUF1992)
NDOFGNNI_03605 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NDOFGNNI_03606 1.5e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NDOFGNNI_03607 1.9e-138 map 3.4.11.18 E Methionine aminopeptidase
NDOFGNNI_03608 2.4e-50 yflH S Protein of unknown function (DUF3243)
NDOFGNNI_03609 4.1e-19 yflI
NDOFGNNI_03610 4e-18 yflJ S Protein of unknown function (DUF2639)
NDOFGNNI_03611 9e-124 yflK S protein conserved in bacteria
NDOFGNNI_03612 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NDOFGNNI_03613 1.3e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NDOFGNNI_03614 5.5e-152 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
NDOFGNNI_03615 1.9e-226 citM C Citrate transporter
NDOFGNNI_03616 2.8e-179 yflP S Tripartite tricarboxylate transporter family receptor
NDOFGNNI_03617 8.9e-119 citT T response regulator
NDOFGNNI_03618 5.3e-287 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NDOFGNNI_03619 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
NDOFGNNI_03620 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
NDOFGNNI_03621 7.6e-58 yflT S Heat induced stress protein YflT
NDOFGNNI_03622 2.9e-24 S Protein of unknown function (DUF3212)
NDOFGNNI_03623 1.7e-168 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
NDOFGNNI_03624 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NDOFGNNI_03625 2e-167 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NDOFGNNI_03626 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
NDOFGNNI_03627 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
NDOFGNNI_03628 2.2e-213 G Major Facilitator Superfamily
NDOFGNNI_03629 2.5e-189 yfmJ S N-terminal domain of oxidoreductase
NDOFGNNI_03630 3e-75 yfmK 2.3.1.128 K acetyltransferase
NDOFGNNI_03631 7.7e-200 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
NDOFGNNI_03632 1.2e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NDOFGNNI_03633 2.5e-36
NDOFGNNI_03634 1.2e-208 yfmO EGP Major facilitator Superfamily
NDOFGNNI_03635 2.4e-69 yfmP K transcriptional
NDOFGNNI_03636 1.2e-68 yfmQ S Uncharacterised protein from bacillus cereus group
NDOFGNNI_03637 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NDOFGNNI_03638 1.1e-113 yfmS NT chemotaxis protein
NDOFGNNI_03639 1.2e-277 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NDOFGNNI_03640 8.4e-241 yfnA E amino acid
NDOFGNNI_03641 8.1e-131 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NDOFGNNI_03642 4.6e-206 fsr P COG0477 Permeases of the major facilitator superfamily
NDOFGNNI_03643 5e-189 yfnD M Nucleotide-diphospho-sugar transferase
NDOFGNNI_03644 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
NDOFGNNI_03645 3.8e-181 yfnF M Nucleotide-diphospho-sugar transferase
NDOFGNNI_03646 1.9e-172 yfnG 4.2.1.45 M dehydratase
NDOFGNNI_03647 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
NDOFGNNI_03648 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NDOFGNNI_03649 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NDOFGNNI_03650 3.6e-199 yetN S Protein of unknown function (DUF3900)
NDOFGNNI_03651 7.8e-213 yetM CH FAD binding domain
NDOFGNNI_03652 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
NDOFGNNI_03653 5.4e-159 yetK EG EamA-like transporter family
NDOFGNNI_03654 5.3e-105 yetJ S Belongs to the BI1 family
NDOFGNNI_03655 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
NDOFGNNI_03656 5.4e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NDOFGNNI_03657 2.2e-34
NDOFGNNI_03658 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NDOFGNNI_03659 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
NDOFGNNI_03660 8.8e-122 yetF S membrane
NDOFGNNI_03661 3.8e-254 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NDOFGNNI_03662 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
NDOFGNNI_03663 1.3e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NDOFGNNI_03664 9.6e-291 lplA G Bacterial extracellular solute-binding protein
NDOFGNNI_03665 0.0 yetA
NDOFGNNI_03666 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
NDOFGNNI_03667 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
NDOFGNNI_03669 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NDOFGNNI_03670 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NDOFGNNI_03671 9.7e-112 yesV S Protein of unknown function, DUF624
NDOFGNNI_03672 6e-128 yesU S Domain of unknown function (DUF1961)
NDOFGNNI_03673 1.3e-128 E GDSL-like Lipase/Acylhydrolase
NDOFGNNI_03674 0.0 yesS K Transcriptional regulator
NDOFGNNI_03675 2.3e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
NDOFGNNI_03676 1.2e-163 yesQ P Binding-protein-dependent transport system inner membrane component
NDOFGNNI_03677 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
NDOFGNNI_03678 8e-246 yesO G Bacterial extracellular solute-binding protein
NDOFGNNI_03679 6.8e-201 yesN K helix_turn_helix, arabinose operon control protein
NDOFGNNI_03680 0.0 yesM 2.7.13.3 T Histidine kinase
NDOFGNNI_03681 9.2e-102 yesL S Protein of unknown function, DUF624
NDOFGNNI_03682 3e-101 yesJ K Acetyltransferase (GNAT) family
NDOFGNNI_03683 5.2e-104 cotJC P Spore Coat
NDOFGNNI_03684 1.5e-45 cotJB S CotJB protein
NDOFGNNI_03685 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
NDOFGNNI_03686 1.1e-150 yesF GM NAD(P)H-binding
NDOFGNNI_03687 3.1e-80 yesE S SnoaL-like domain
NDOFGNNI_03688 1.2e-103 dhaR3 K Transcriptional regulator
NDOFGNNI_03690 9.4e-127 yeeN K transcriptional regulatory protein
NDOFGNNI_03692 8.7e-212 S Tetratricopeptide repeat
NDOFGNNI_03693 1.8e-192 3.4.24.40 CO amine dehydrogenase activity
NDOFGNNI_03694 0.0 L nucleic acid phosphodiester bond hydrolysis
NDOFGNNI_03695 5.5e-83 S Protein of unknown function, DUF600
NDOFGNNI_03696 6.2e-31 S Colicin immunity protein / pyocin immunity protein
NDOFGNNI_03698 1.2e-211 pstS P T5orf172
NDOFGNNI_03699 0.0 yeeB L DEAD-like helicases superfamily
NDOFGNNI_03700 0.0 yeeA V Type II restriction enzyme, methylase subunits
NDOFGNNI_03701 3.2e-53 L Resolvase, N terminal domain
NDOFGNNI_03702 3.2e-98 L Recombinase
NDOFGNNI_03703 1.2e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NDOFGNNI_03704 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NDOFGNNI_03705 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NDOFGNNI_03706 4e-156 yerO K Transcriptional regulator
NDOFGNNI_03707 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NDOFGNNI_03708 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NDOFGNNI_03709 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NDOFGNNI_03710 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NDOFGNNI_03711 1.6e-123 sapB S MgtC SapB transporter
NDOFGNNI_03712 2.7e-196 yerI S homoserine kinase type II (protein kinase fold)
NDOFGNNI_03713 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
NDOFGNNI_03714 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NDOFGNNI_03715 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NDOFGNNI_03716 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NDOFGNNI_03718 1.5e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
NDOFGNNI_03719 4.8e-51 yerC S protein conserved in bacteria
NDOFGNNI_03720 8.3e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
NDOFGNNI_03721 0.0 yerA 3.5.4.2 F adenine deaminase
NDOFGNNI_03722 5.1e-26 S Protein of unknown function (DUF2892)
NDOFGNNI_03723 4.7e-230 yjeH E Amino acid permease
NDOFGNNI_03724 7.3e-71 K helix_turn_helix ASNC type
NDOFGNNI_03725 2.2e-232 purD 6.3.4.13 F Belongs to the GARS family
NDOFGNNI_03726 1.3e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NDOFGNNI_03727 1.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NDOFGNNI_03728 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NDOFGNNI_03729 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NDOFGNNI_03730 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NDOFGNNI_03731 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NDOFGNNI_03732 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NDOFGNNI_03733 2.8e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NDOFGNNI_03734 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NDOFGNNI_03735 1e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NDOFGNNI_03736 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NDOFGNNI_03737 8e-28 yebG S NETI protein
NDOFGNNI_03738 4e-93 yebE S UPF0316 protein
NDOFGNNI_03740 6.8e-118 yebC M Membrane
NDOFGNNI_03741 7.8e-212 pbuG S permease
NDOFGNNI_03742 1.4e-305 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NDOFGNNI_03743 0.0 yebA E COG1305 Transglutaminase-like enzymes
NDOFGNNI_03744 1.2e-222 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NDOFGNNI_03745 1.7e-176 yeaC S COG0714 MoxR-like ATPases
NDOFGNNI_03746 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NDOFGNNI_03747 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
NDOFGNNI_03748 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
NDOFGNNI_03749 3.3e-175 yeaA S Protein of unknown function (DUF4003)
NDOFGNNI_03750 8.4e-156 ydjP I Alpha/beta hydrolase family
NDOFGNNI_03751 1.4e-34 ydjO S Cold-inducible protein YdjO
NDOFGNNI_03753 3.6e-151 ydjN U Involved in the tonB-independent uptake of proteins
NDOFGNNI_03754 4.5e-64 ydjM M Lytic transglycolase
NDOFGNNI_03755 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
NDOFGNNI_03756 2.7e-258 iolT EGP Major facilitator Superfamily
NDOFGNNI_03757 4.7e-196 S Ion transport 2 domain protein
NDOFGNNI_03758 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
NDOFGNNI_03759 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
NDOFGNNI_03760 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NDOFGNNI_03761 5.1e-114 pspA KT Phage shock protein A
NDOFGNNI_03762 4.3e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
NDOFGNNI_03763 4.3e-253 gutA G MFS/sugar transport protein
NDOFGNNI_03764 7.2e-200 gutB 1.1.1.14 E Dehydrogenase
NDOFGNNI_03765 0.0 K NB-ARC domain
NDOFGNNI_03766 1.1e-08 ydjC S Abhydrolase domain containing 18
NDOFGNNI_03767 4.9e-257 J LlaJI restriction endonuclease
NDOFGNNI_03768 1.2e-199 V AAA domain (dynein-related subfamily)
NDOFGNNI_03770 1.6e-232 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
NDOFGNNI_03771 1.1e-250 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
NDOFGNNI_03772 6.4e-66 KL Phage plasmid primase P4 family
NDOFGNNI_03774 1.2e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NDOFGNNI_03775 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NDOFGNNI_03776 3e-128 ydiL S CAAX protease self-immunity
NDOFGNNI_03777 2.9e-27 ydiK S Domain of unknown function (DUF4305)
NDOFGNNI_03778 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NDOFGNNI_03779 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NDOFGNNI_03780 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NDOFGNNI_03781 2.1e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NDOFGNNI_03782 0.0 ydiF S ABC transporter
NDOFGNNI_03783 2e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NDOFGNNI_03784 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NDOFGNNI_03785 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
NDOFGNNI_03786 5.9e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
NDOFGNNI_03787 1.3e-179 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NDOFGNNI_03789 7.8e-08
NDOFGNNI_03790 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NDOFGNNI_03791 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NDOFGNNI_03792 1.8e-37 yaaB S Domain of unknown function (DUF370)
NDOFGNNI_03793 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NDOFGNNI_03794 2.4e-33 yaaA S S4 domain
NDOFGNNI_03795 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NDOFGNNI_03796 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NDOFGNNI_03797 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NDOFGNNI_03798 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NDOFGNNI_03799 7.2e-107 jag S single-stranded nucleic acid binding R3H
NDOFGNNI_03800 2e-250 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NDOFGNNI_03801 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NDOFGNNI_03802 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NDOFGNNI_03803 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NDOFGNNI_03804 9.6e-74 S Bacterial PH domain
NDOFGNNI_03805 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
NDOFGNNI_03806 2.1e-149 spo0J K Belongs to the ParB family
NDOFGNNI_03807 1.6e-111 yyaC S Sporulation protein YyaC
NDOFGNNI_03808 8.1e-177 yyaD S Membrane
NDOFGNNI_03809 2.3e-33 yyzM S protein conserved in bacteria
NDOFGNNI_03810 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NDOFGNNI_03811 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NDOFGNNI_03812 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
NDOFGNNI_03813 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NDOFGNNI_03814 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NDOFGNNI_03815 5.8e-143 xth 3.1.11.2 L exodeoxyribonuclease III
NDOFGNNI_03816 2.6e-177 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
NDOFGNNI_03817 8.4e-66 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NDOFGNNI_03818 2.8e-94 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
NDOFGNNI_03819 1.8e-243 EGP Major facilitator superfamily
NDOFGNNI_03820 8e-168 yyaK S CAAX protease self-immunity
NDOFGNNI_03821 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
NDOFGNNI_03822 3.3e-161 yyaM EG EamA-like transporter family
NDOFGNNI_03823 5.1e-61 yyaN K MerR HTH family regulatory protein
NDOFGNNI_03824 2.6e-13 S Putative amidase domain
NDOFGNNI_03826 2.4e-248 tetL EGP Major facilitator Superfamily
NDOFGNNI_03827 6.1e-105 yyaP 1.5.1.3 H RibD C-terminal domain
NDOFGNNI_03828 1e-65 yyaQ S YjbR
NDOFGNNI_03829 3e-90 yyaR K Acetyltransferase (GNAT) domain
NDOFGNNI_03830 2.5e-96 yyaS S Membrane
NDOFGNNI_03831 1.2e-71 yjcF S Acetyltransferase (GNAT) domain
NDOFGNNI_03832 5.6e-77 yybA 2.3.1.57 K transcriptional
NDOFGNNI_03833 6.2e-125 S Metallo-beta-lactamase superfamily
NDOFGNNI_03834 3e-76 yybC
NDOFGNNI_03835 7.7e-79 yjcF S Acetyltransferase (GNAT) domain
NDOFGNNI_03836 1.2e-163 yybE K Transcriptional regulator
NDOFGNNI_03837 6.3e-216 ynfM EGP Major facilitator Superfamily
NDOFGNNI_03838 2.6e-120 yybG S Pentapeptide repeat-containing protein
NDOFGNNI_03839 5.5e-65 yybH S SnoaL-like domain
NDOFGNNI_03840 4.9e-129
NDOFGNNI_03841 2.6e-115 V ATPases associated with a variety of cellular activities
NDOFGNNI_03842 2e-127 S Protein of unknown function (DUF2705)
NDOFGNNI_03843 9e-122
NDOFGNNI_03844 4.1e-125
NDOFGNNI_03845 1.3e-78 yybN S Protein of unknown function (DUF2712)
NDOFGNNI_03846 1e-16
NDOFGNNI_03847 3.9e-240 yybO G COG0477 Permeases of the major facilitator superfamily
NDOFGNNI_03849 1.6e-60
NDOFGNNI_03850 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
NDOFGNNI_03851 1.7e-66 ydeP3 K Transcriptional regulator
NDOFGNNI_03852 3.9e-84 cotF M Spore coat protein
NDOFGNNI_03854 8.3e-160 yybS S membrane
NDOFGNNI_03855 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NDOFGNNI_03856 4.9e-73 rplI J binds to the 23S rRNA
NDOFGNNI_03857 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NDOFGNNI_03858 7.1e-220 yeaN P COG2807 Cyanate permease
NDOFGNNI_03859 1.9e-15 yycC K YycC-like protein
NDOFGNNI_03861 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
NDOFGNNI_03862 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NDOFGNNI_03863 8.9e-77 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NDOFGNNI_03864 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NDOFGNNI_03869 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NDOFGNNI_03870 0.0 vicK 2.7.13.3 T Histidine kinase
NDOFGNNI_03871 1.5e-258 yycH S protein conserved in bacteria
NDOFGNNI_03872 1.8e-153 yycI S protein conserved in bacteria
NDOFGNNI_03873 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NDOFGNNI_03874 8.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NDOFGNNI_03875 1.4e-33 S Peptidase propeptide and YPEB domain
NDOFGNNI_03876 1.2e-73 S Peptidase propeptide and YPEB domain
NDOFGNNI_03877 1.5e-94 K PFAM response regulator receiver
NDOFGNNI_03878 9.6e-171 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
NDOFGNNI_03879 2.6e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NDOFGNNI_03880 4.3e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
NDOFGNNI_03881 9.7e-261 rocE E amino acid
NDOFGNNI_03882 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
NDOFGNNI_03884 8.5e-188 S aspartate phosphatase
NDOFGNNI_03885 2.2e-84 yycN 2.3.1.128 K Acetyltransferase
NDOFGNNI_03886 3.8e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NDOFGNNI_03887 1.2e-208 yycP
NDOFGNNI_03888 5.7e-31 yycQ S Protein of unknown function (DUF2651)
NDOFGNNI_03890 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NDOFGNNI_03891 4.2e-71
NDOFGNNI_03892 1.1e-09 S YyzF-like protein
NDOFGNNI_03893 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NDOFGNNI_03894 0.0 O growth
NDOFGNNI_03895 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
NDOFGNNI_03896 1.6e-109 prrC P ABC transporter
NDOFGNNI_03897 1.6e-118 S ABC-2 family transporter protein
NDOFGNNI_03898 1.5e-124 yydK K Transcriptional regulator
NDOFGNNI_03899 2.3e-34 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
NDOFGNNI_03900 3.5e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NDOFGNNI_03901 3.3e-286 ahpF O Alkyl hydroperoxide reductase
NDOFGNNI_03902 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
NDOFGNNI_03903 3.8e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NDOFGNNI_03904 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
NDOFGNNI_03905 3.9e-303 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
NDOFGNNI_03906 2.8e-126 gntR K transcriptional
NDOFGNNI_03907 6.6e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NDOFGNNI_03908 1.7e-193 yxaB GM Polysaccharide pyruvyl transferase
NDOFGNNI_03909 1.3e-117 yxaC M effector of murein hydrolase
NDOFGNNI_03910 5.2e-50 S LrgA family
NDOFGNNI_03911 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
NDOFGNNI_03912 1.9e-200 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NDOFGNNI_03913 1.2e-100 yxaF K Transcriptional regulator
NDOFGNNI_03914 1.3e-198 yxaG 1.13.11.24 S AraC-like ligand binding domain
NDOFGNNI_03915 1.4e-228 P Protein of unknown function (DUF418)
NDOFGNNI_03916 1.1e-75 yxaI S membrane protein domain
NDOFGNNI_03917 3.5e-65 S Family of unknown function (DUF5391)
NDOFGNNI_03918 6.8e-93 S PQQ-like domain
NDOFGNNI_03919 7.6e-214 yxaM U MFS_1 like family
NDOFGNNI_03920 0.0 asnB 6.3.5.4 E Asparagine synthase
NDOFGNNI_03921 1.1e-86 yxnB
NDOFGNNI_03922 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
NDOFGNNI_03923 3.3e-127 yxbB Q Met-10+ like-protein
NDOFGNNI_03924 4.3e-60 S Phage tail protein
NDOFGNNI_03925 2.4e-147 S Phage minor structural protein
NDOFGNNI_03926 5.3e-23
NDOFGNNI_03927 5.4e-77 S N-acetylmuramoyl-L-alanine amidase activity
NDOFGNNI_03928 6.7e-12
NDOFGNNI_03931 1.5e-09 S SPP1 phage holin
NDOFGNNI_03932 4.7e-108 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 CBM50 M Glycosyl hydrolases family 25
NDOFGNNI_03933 2.1e-97 S Phage integrase family
NDOFGNNI_03934 2.5e-175 A Pre-toxin TG
NDOFGNNI_03935 2.3e-64 S Immunity protein 70
NDOFGNNI_03936 3.1e-32 S Domain of unknown function (DUF4935)
NDOFGNNI_03938 5.4e-13 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
NDOFGNNI_03944 4.4e-57 traC L Domain of unknown function (DUF1738)
NDOFGNNI_03945 5.4e-148 S DNA gyrase/topoisomerase IV, subunit A
NDOFGNNI_03946 2e-184 S DNA gyrase B
NDOFGNNI_03947 4e-15 repA S Replication initiator protein A (RepA) N-terminus
NDOFGNNI_03949 1.5e-10 tdk 2.7.1.21 F Thymidine kinase
NDOFGNNI_03955 3.3e-18 S Endodeoxyribonuclease RusA
NDOFGNNI_03956 2.8e-22 2.7.4.8 F Guanylate kinase homologues.
NDOFGNNI_03960 0.0 S Bacterial DNA polymerase III alpha subunit
NDOFGNNI_03962 4.4e-10 thyX 2.1.1.148 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
NDOFGNNI_03964 1.8e-46 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NDOFGNNI_03968 7.6e-07 yfbR S HD containing hydrolase-like enzyme
NDOFGNNI_03970 2.3e-17 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
NDOFGNNI_03971 1.9e-15 K Transcriptional regulator
NDOFGNNI_03972 1.2e-87 S exonuclease activity
NDOFGNNI_03974 1.7e-89 S DNA primase activity
NDOFGNNI_03975 7.9e-110 S DNA helicase activity
NDOFGNNI_03976 3.9e-15
NDOFGNNI_03977 8.7e-36
NDOFGNNI_03979 1e-39
NDOFGNNI_03981 3.4e-10 fld C flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
NDOFGNNI_03982 1.2e-103 S Ribonucleotide reductase, small chain
NDOFGNNI_03983 4.3e-277 S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
NDOFGNNI_03984 1.9e-64 S AAA domain
NDOFGNNI_03987 1.7e-48 F Nucleoside 2-deoxyribosyltransferase
NDOFGNNI_03988 3.9e-35
NDOFGNNI_03990 2.9e-39
NDOFGNNI_03991 1.5e-31 yxcD S Protein of unknown function (DUF2653)
NDOFGNNI_03993 8.1e-20
NDOFGNNI_03994 3.4e-41 XK27_03185 S Phosphoribosyl-ATP pyrophosphohydrolase
NDOFGNNI_03997 2e-53
NDOFGNNI_03998 3.6e-73 L integrase family
NDOFGNNI_04002 2e-22 yocH 3.5.1.28 M 3D domain
NDOFGNNI_04003 1.2e-68 lig 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP dependent DNA ligase domain
NDOFGNNI_04005 3.3e-83
NDOFGNNI_04007 2.9e-178 S response regulator aspartate phosphatase
NDOFGNNI_04010 6.2e-29 S Phage terminase, small subunit
NDOFGNNI_04013 2.1e-106 S Phage portal protein
NDOFGNNI_04014 1.9e-55 S Caudovirus prohead serine protease
NDOFGNNI_04015 6.8e-87 S Phage capsid family
NDOFGNNI_04017 1.4e-21 S DNA packaging
NDOFGNNI_04018 1.8e-11 S Phage head-tail joining protein
NDOFGNNI_04019 7.4e-14 S Bacteriophage HK97-gp10, putative tail-component
NDOFGNNI_04020 1.9e-07
NDOFGNNI_04021 1.6e-40 S Phage tail tube protein
NDOFGNNI_04023 2.5e-173 D Phage tail tape measure protein
NDOFGNNI_04024 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
NDOFGNNI_04025 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
NDOFGNNI_04026 1.2e-84 gerD
NDOFGNNI_04027 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NDOFGNNI_04028 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NDOFGNNI_04029 9.7e-66 ybaK S Protein of unknown function (DUF2521)
NDOFGNNI_04030 2.4e-144 ybaJ Q Methyltransferase domain
NDOFGNNI_04031 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
NDOFGNNI_04032 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NDOFGNNI_04033 8.2e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NDOFGNNI_04034 1.4e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NDOFGNNI_04035 5.4e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NDOFGNNI_04036 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NDOFGNNI_04037 3.6e-58 rplQ J Ribosomal protein L17
NDOFGNNI_04038 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NDOFGNNI_04039 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NDOFGNNI_04040 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NDOFGNNI_04041 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NDOFGNNI_04042 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NDOFGNNI_04043 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
NDOFGNNI_04044 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NDOFGNNI_04045 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NDOFGNNI_04046 1.8e-72 rplO J binds to the 23S rRNA
NDOFGNNI_04047 1.9e-23 rpmD J Ribosomal protein L30
NDOFGNNI_04048 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NDOFGNNI_04049 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NDOFGNNI_04050 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NDOFGNNI_04051 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NDOFGNNI_04052 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NDOFGNNI_04053 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NDOFGNNI_04054 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NDOFGNNI_04055 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NDOFGNNI_04056 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NDOFGNNI_04057 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
NDOFGNNI_04058 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NDOFGNNI_04059 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NDOFGNNI_04060 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NDOFGNNI_04061 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NDOFGNNI_04062 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NDOFGNNI_04063 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NDOFGNNI_04064 3e-105 rplD J Forms part of the polypeptide exit tunnel
NDOFGNNI_04065 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NDOFGNNI_04066 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NDOFGNNI_04067 9.1e-186 ybaC 3.4.11.5 S Alpha/beta hydrolase family
NDOFGNNI_04068 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NDOFGNNI_04069 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NDOFGNNI_04070 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NDOFGNNI_04071 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NDOFGNNI_04072 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
NDOFGNNI_04073 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NDOFGNNI_04074 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NDOFGNNI_04075 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
NDOFGNNI_04076 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NDOFGNNI_04077 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NDOFGNNI_04078 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NDOFGNNI_04079 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NDOFGNNI_04080 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
NDOFGNNI_04081 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NDOFGNNI_04082 4.4e-115 sigH K Belongs to the sigma-70 factor family
NDOFGNNI_04083 1.2e-88 yacP S RNA-binding protein containing a PIN domain
NDOFGNNI_04084 1.2e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NDOFGNNI_04085 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NDOFGNNI_04086 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NDOFGNNI_04087 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
NDOFGNNI_04088 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NDOFGNNI_04089 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NDOFGNNI_04090 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NDOFGNNI_04091 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
NDOFGNNI_04092 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NDOFGNNI_04093 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NDOFGNNI_04094 0.0 clpC O Belongs to the ClpA ClpB family
NDOFGNNI_04095 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NDOFGNNI_04096 4.7e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
NDOFGNNI_04097 2.9e-76 ctsR K Belongs to the CtsR family
NDOFGNNI_04098 3.4e-31 csfB S Inhibitor of sigma-G Gin
NDOFGNNI_04099 4.4e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NDOFGNNI_04100 8.4e-202 yaaN P Belongs to the TelA family
NDOFGNNI_04101 2.3e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
NDOFGNNI_04102 1.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NDOFGNNI_04103 2.2e-54 yaaQ S protein conserved in bacteria
NDOFGNNI_04104 1.5e-71 yaaR S protein conserved in bacteria
NDOFGNNI_04105 4.8e-182 holB 2.7.7.7 L DNA polymerase III
NDOFGNNI_04106 6.1e-146 yaaT S stage 0 sporulation protein
NDOFGNNI_04107 4.8e-31 yabA L Involved in initiation control of chromosome replication
NDOFGNNI_04108 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
NDOFGNNI_04109 2.8e-48 yazA L endonuclease containing a URI domain
NDOFGNNI_04110 1e-151 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NDOFGNNI_04111 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
NDOFGNNI_04112 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NDOFGNNI_04113 1.2e-143 tatD L hydrolase, TatD
NDOFGNNI_04114 4.3e-194 rpfB GH23 T protein conserved in bacteria
NDOFGNNI_04115 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NDOFGNNI_04116 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NDOFGNNI_04117 1.6e-136 yabG S peptidase
NDOFGNNI_04118 7.8e-39 veg S protein conserved in bacteria
NDOFGNNI_04119 8.3e-27 sspF S DNA topological change
NDOFGNNI_04120 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NDOFGNNI_04121 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NDOFGNNI_04122 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
NDOFGNNI_04123 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NDOFGNNI_04124 6.6e-230 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NDOFGNNI_04125 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NDOFGNNI_04126 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NDOFGNNI_04127 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NDOFGNNI_04128 2.4e-39 yabK S Peptide ABC transporter permease
NDOFGNNI_04129 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NDOFGNNI_04130 1.5e-92 spoVT K stage V sporulation protein
NDOFGNNI_04131 3.3e-281 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NDOFGNNI_04132 1.9e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NDOFGNNI_04133 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NDOFGNNI_04134 1.5e-49 yabP S Sporulation protein YabP
NDOFGNNI_04135 4.3e-107 yabQ S spore cortex biosynthesis protein
NDOFGNNI_04136 1.1e-44 divIC D Septum formation initiator
NDOFGNNI_04137 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
NDOFGNNI_04140 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
NDOFGNNI_04141 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
NDOFGNNI_04142 1.1e-184 KLT serine threonine protein kinase
NDOFGNNI_04143 6.5e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NDOFGNNI_04144 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NDOFGNNI_04145 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NDOFGNNI_04146 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NDOFGNNI_04147 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NDOFGNNI_04148 3.1e-153 yacD 5.2.1.8 O peptidyl-prolyl isomerase
NDOFGNNI_04149 7.5e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NDOFGNNI_04150 4.7e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NDOFGNNI_04151 1.5e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
NDOFGNNI_04152 1.6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
NDOFGNNI_04153 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NDOFGNNI_04154 8.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NDOFGNNI_04155 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NDOFGNNI_04156 4.1e-30 yazB K transcriptional
NDOFGNNI_04157 3.7e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NDOFGNNI_04158 1.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NDOFGNNI_04159 8.2e-36 bofA S Sigma-K factor-processing regulatory protein BofA
NDOFGNNI_04160 7.9e-32 yaaL S Protein of unknown function (DUF2508)
NDOFGNNI_04161 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NDOFGNNI_04162 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NDOFGNNI_04163 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NDOFGNNI_04164 1e-84 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NDOFGNNI_04165 2.4e-98 yaaI Q COG1335 Amidases related to nicotinamidase
NDOFGNNI_04166 5.6e-215 yaaH M Glycoside Hydrolase Family
NDOFGNNI_04167 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
NDOFGNNI_04168 6.3e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
NDOFGNNI_04169 1.3e-09
NDOFGNNI_04170 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NDOFGNNI_04171 2.3e-107 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NDOFGNNI_04172 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NDOFGNNI_04173 5.2e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NDOFGNNI_04174 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NDOFGNNI_04175 2.7e-182 yaaC S YaaC-like Protein
NDOFGNNI_04180 2e-08
NDOFGNNI_04185 3.4e-39 S COG NOG14552 non supervised orthologous group
NDOFGNNI_04187 2e-08
NDOFGNNI_04192 7.4e-42 S protein conserved in bacteria
NDOFGNNI_04195 3.9e-57 ygbL 4.1.1.104, 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
NDOFGNNI_04196 3.5e-52 mltD 3.5.1.28 M in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall
NDOFGNNI_04197 5.2e-62 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NDOFGNNI_04198 7.1e-16 K PFAM response regulator receiver

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)