ORF_ID e_value Gene_name EC_number CAZy COGs Description
NIPEHPHG_00005 7.8e-08
NIPEHPHG_00013 2e-08
NIPEHPHG_00017 2.7e-143 spo0M S COG4326 Sporulation control protein
NIPEHPHG_00018 3e-27
NIPEHPHG_00019 5.9e-134 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
NIPEHPHG_00020 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NIPEHPHG_00021 1.9e-266 ygaK C Berberine and berberine like
NIPEHPHG_00023 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NIPEHPHG_00024 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NIPEHPHG_00025 1.7e-171 ssuA M Sulfonate ABC transporter
NIPEHPHG_00026 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NIPEHPHG_00027 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
NIPEHPHG_00029 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NIPEHPHG_00030 4.1e-78 ygaO
NIPEHPHG_00031 4.4e-29 K Transcriptional regulator
NIPEHPHG_00033 7.9e-114 yhzB S B3/4 domain
NIPEHPHG_00034 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NIPEHPHG_00035 4.4e-177 yhbB S Putative amidase domain
NIPEHPHG_00036 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NIPEHPHG_00037 1.2e-109 yhbD K Protein of unknown function (DUF4004)
NIPEHPHG_00038 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
NIPEHPHG_00039 8.2e-75 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
NIPEHPHG_00040 0.0 prkA T Ser protein kinase
NIPEHPHG_00041 2.5e-225 yhbH S Belongs to the UPF0229 family
NIPEHPHG_00042 2.2e-76 yhbI K DNA-binding transcription factor activity
NIPEHPHG_00043 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
NIPEHPHG_00044 3.1e-271 yhcA EGP Major facilitator Superfamily
NIPEHPHG_00045 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
NIPEHPHG_00046 2.8e-37 yhcC
NIPEHPHG_00047 7.8e-55
NIPEHPHG_00048 6.6e-60 yhcF K Transcriptional regulator
NIPEHPHG_00049 1.6e-123 yhcG V ABC transporter, ATP-binding protein
NIPEHPHG_00050 2.6e-166 yhcH V ABC transporter, ATP-binding protein
NIPEHPHG_00051 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NIPEHPHG_00052 1e-30 cspB K Cold-shock protein
NIPEHPHG_00053 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
NIPEHPHG_00054 1.2e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
NIPEHPHG_00055 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NIPEHPHG_00056 3.7e-44 yhcM
NIPEHPHG_00057 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NIPEHPHG_00058 2.5e-167 yhcP
NIPEHPHG_00059 5.2e-100 yhcQ M Spore coat protein
NIPEHPHG_00060 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
NIPEHPHG_00061 7.6e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
NIPEHPHG_00062 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NIPEHPHG_00063 9.3e-68 yhcU S Family of unknown function (DUF5365)
NIPEHPHG_00064 9.9e-68 yhcV S COG0517 FOG CBS domain
NIPEHPHG_00065 4.6e-120 yhcW 5.4.2.6 S hydrolase
NIPEHPHG_00066 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NIPEHPHG_00067 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NIPEHPHG_00068 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NIPEHPHG_00069 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
NIPEHPHG_00070 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NIPEHPHG_00071 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NIPEHPHG_00072 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
NIPEHPHG_00073 5.5e-214 yhcY 2.7.13.3 T Histidine kinase
NIPEHPHG_00074 1.1e-113 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NIPEHPHG_00075 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
NIPEHPHG_00076 1.2e-38 yhdB S YhdB-like protein
NIPEHPHG_00077 4.8e-54 yhdC S Protein of unknown function (DUF3889)
NIPEHPHG_00078 7.9e-189 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NIPEHPHG_00079 3.5e-76 nsrR K Transcriptional regulator
NIPEHPHG_00080 8.7e-239 ygxB M Conserved TM helix
NIPEHPHG_00081 2.1e-276 ycgB S Stage V sporulation protein R
NIPEHPHG_00082 5.8e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NIPEHPHG_00083 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NIPEHPHG_00084 3.8e-162 citR K Transcriptional regulator
NIPEHPHG_00085 1.4e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
NIPEHPHG_00086 4.9e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NIPEHPHG_00087 3.4e-250 yhdG E amino acid
NIPEHPHG_00088 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NIPEHPHG_00089 3.7e-276 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NIPEHPHG_00090 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NIPEHPHG_00091 8.1e-45 yhdK S Sigma-M inhibitor protein
NIPEHPHG_00092 6.6e-201 yhdL S Sigma factor regulator N-terminal
NIPEHPHG_00093 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
NIPEHPHG_00094 1.5e-191 yhdN C Aldo keto reductase
NIPEHPHG_00095 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NIPEHPHG_00096 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NIPEHPHG_00097 4.1e-74 cueR K transcriptional
NIPEHPHG_00098 1.4e-223 yhdR 2.6.1.1 E Aminotransferase
NIPEHPHG_00099 1.1e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
NIPEHPHG_00100 2.8e-47 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NIPEHPHG_00101 5.1e-66 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NIPEHPHG_00102 3.3e-135 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NIPEHPHG_00104 6.6e-204 yhdY M Mechanosensitive ion channel
NIPEHPHG_00105 1.2e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NIPEHPHG_00106 1.7e-151 yheN G deacetylase
NIPEHPHG_00107 1.1e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NIPEHPHG_00108 2.2e-233 nhaC C Na H antiporter
NIPEHPHG_00109 3.4e-84 nhaX T Belongs to the universal stress protein A family
NIPEHPHG_00110 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
NIPEHPHG_00111 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
NIPEHPHG_00112 3.7e-111 yheG GM NAD(P)H-binding
NIPEHPHG_00113 6.3e-28 sspB S spore protein
NIPEHPHG_00114 1.3e-36 yheE S Family of unknown function (DUF5342)
NIPEHPHG_00115 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
NIPEHPHG_00116 4.3e-216 yheC HJ YheC/D like ATP-grasp
NIPEHPHG_00117 6.7e-204 yheB S Belongs to the UPF0754 family
NIPEHPHG_00118 9.5e-48 yheA S Belongs to the UPF0342 family
NIPEHPHG_00119 3.1e-206 yhaZ L DNA alkylation repair enzyme
NIPEHPHG_00120 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
NIPEHPHG_00121 7.1e-294 hemZ H coproporphyrinogen III oxidase
NIPEHPHG_00122 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
NIPEHPHG_00123 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
NIPEHPHG_00125 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
NIPEHPHG_00126 1.1e-26 S YhzD-like protein
NIPEHPHG_00127 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
NIPEHPHG_00128 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
NIPEHPHG_00129 3.6e-227 yhaO L DNA repair exonuclease
NIPEHPHG_00130 0.0 yhaN L AAA domain
NIPEHPHG_00131 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
NIPEHPHG_00132 1.6e-21 yhaL S Sporulation protein YhaL
NIPEHPHG_00133 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NIPEHPHG_00134 8.7e-90 yhaK S Putative zincin peptidase
NIPEHPHG_00135 1.3e-54 yhaI S Protein of unknown function (DUF1878)
NIPEHPHG_00136 1e-113 hpr K Negative regulator of protease production and sporulation
NIPEHPHG_00137 7e-39 yhaH S YtxH-like protein
NIPEHPHG_00138 3.6e-80 trpP S Tryptophan transporter TrpP
NIPEHPHG_00139 9.9e-205 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NIPEHPHG_00140 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NIPEHPHG_00141 4.6e-137 ecsA V transporter (ATP-binding protein)
NIPEHPHG_00142 1.8e-215 ecsB U ABC transporter
NIPEHPHG_00143 4.8e-115 ecsC S EcsC protein family
NIPEHPHG_00144 2.3e-231 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NIPEHPHG_00145 4.2e-248 yhfA C membrane
NIPEHPHG_00146 7.5e-17 1.15.1.2 C Rubrerythrin
NIPEHPHG_00147 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NIPEHPHG_00148 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NIPEHPHG_00149 1.7e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NIPEHPHG_00150 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NIPEHPHG_00151 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NIPEHPHG_00152 1.4e-101 yhgD K Transcriptional regulator
NIPEHPHG_00153 5e-238 yhgE S YhgE Pip N-terminal domain protein
NIPEHPHG_00154 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NIPEHPHG_00155 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
NIPEHPHG_00156 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
NIPEHPHG_00157 1.7e-72 3.4.13.21 S ASCH
NIPEHPHG_00158 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NIPEHPHG_00159 6.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NIPEHPHG_00160 2e-191 lplJ 6.3.1.20 H Lipoate-protein ligase
NIPEHPHG_00161 2.6e-112 yhfK GM NmrA-like family
NIPEHPHG_00162 7.3e-302 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NIPEHPHG_00163 1.9e-65 yhfM
NIPEHPHG_00164 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
NIPEHPHG_00165 2.3e-204 aprE 3.4.21.62 O Belongs to the peptidase S8 family
NIPEHPHG_00166 9.2e-80 VY92_01935 K acetyltransferase
NIPEHPHG_00167 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
NIPEHPHG_00168 4.3e-159 yfmC M Periplasmic binding protein
NIPEHPHG_00169 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NIPEHPHG_00170 2.3e-201 vraB 2.3.1.9 I Belongs to the thiolase family
NIPEHPHG_00171 1e-281 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NIPEHPHG_00172 5e-91 bioY S BioY family
NIPEHPHG_00173 1.7e-182 hemAT NT chemotaxis protein
NIPEHPHG_00174 1.1e-302 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
NIPEHPHG_00175 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NIPEHPHG_00176 1.3e-32 yhzC S IDEAL
NIPEHPHG_00177 4.2e-109 comK K Competence transcription factor
NIPEHPHG_00178 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
NIPEHPHG_00179 7.8e-42 yhjA S Excalibur calcium-binding domain
NIPEHPHG_00180 6.1e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NIPEHPHG_00181 6.9e-27 yhjC S Protein of unknown function (DUF3311)
NIPEHPHG_00182 5e-60 yhjD
NIPEHPHG_00183 9.1e-110 yhjE S SNARE associated Golgi protein
NIPEHPHG_00184 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
NIPEHPHG_00185 1.1e-286 yhjG CH FAD binding domain
NIPEHPHG_00186 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
NIPEHPHG_00187 6.9e-215 glcP G Major Facilitator Superfamily
NIPEHPHG_00188 1.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
NIPEHPHG_00189 1.8e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
NIPEHPHG_00190 4.4e-255 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
NIPEHPHG_00191 1.6e-188 yhjM 5.1.1.1 K Transcriptional regulator
NIPEHPHG_00192 3.8e-202 abrB S membrane
NIPEHPHG_00193 3.1e-215 EGP Transmembrane secretion effector
NIPEHPHG_00194 0.0 S Sugar transport-related sRNA regulator N-term
NIPEHPHG_00195 2e-36 yhjQ C COG1145 Ferredoxin
NIPEHPHG_00196 2.2e-78 yhjR S Rubrerythrin
NIPEHPHG_00197 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
NIPEHPHG_00198 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NIPEHPHG_00199 1.7e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NIPEHPHG_00200 0.0 sbcC L COG0419 ATPase involved in DNA repair
NIPEHPHG_00201 6e-51 yisB V COG1403 Restriction endonuclease
NIPEHPHG_00202 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
NIPEHPHG_00203 3e-66 gerPE S Spore germination protein GerPE
NIPEHPHG_00204 6.3e-24 gerPD S Spore germination protein
NIPEHPHG_00205 1.8e-54 gerPC S Spore germination protein
NIPEHPHG_00206 4e-34 gerPB S cell differentiation
NIPEHPHG_00207 1.9e-33 gerPA S Spore germination protein
NIPEHPHG_00208 1.5e-22 yisI S Spo0E like sporulation regulatory protein
NIPEHPHG_00209 1.7e-176 cotH M Spore Coat
NIPEHPHG_00210 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NIPEHPHG_00211 3e-57 yisL S UPF0344 protein
NIPEHPHG_00212 0.0 wprA O Belongs to the peptidase S8 family
NIPEHPHG_00213 7.2e-106 yisN S Protein of unknown function (DUF2777)
NIPEHPHG_00214 0.0 asnO 6.3.5.4 E Asparagine synthase
NIPEHPHG_00215 2.1e-88 yizA S Damage-inducible protein DinB
NIPEHPHG_00216 6.8e-150 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
NIPEHPHG_00217 4e-243 yisQ V Mate efflux family protein
NIPEHPHG_00218 3.5e-160 yisR K Transcriptional regulator
NIPEHPHG_00219 2.4e-184 purR K helix_turn _helix lactose operon repressor
NIPEHPHG_00220 4.5e-199 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
NIPEHPHG_00221 1.3e-93 yisT S DinB family
NIPEHPHG_00222 6.4e-108 argO S Lysine exporter protein LysE YggA
NIPEHPHG_00223 1.7e-281 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NIPEHPHG_00224 4e-36 mcbG S Pentapeptide repeats (9 copies)
NIPEHPHG_00225 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NIPEHPHG_00226 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
NIPEHPHG_00227 3.2e-233 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NIPEHPHG_00228 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NIPEHPHG_00229 4.9e-125 comB 3.1.3.71 H Belongs to the ComB family
NIPEHPHG_00230 1.9e-141 yitD 4.4.1.19 S synthase
NIPEHPHG_00231 7.2e-113 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NIPEHPHG_00232 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NIPEHPHG_00233 4e-229 yitG EGP Major facilitator Superfamily
NIPEHPHG_00234 1.8e-161 yitH K Acetyltransferase (GNAT) domain
NIPEHPHG_00235 5.8e-82 yjcF S Acetyltransferase (GNAT) domain
NIPEHPHG_00236 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NIPEHPHG_00237 8.6e-55 yajQ S Belongs to the UPF0234 family
NIPEHPHG_00238 4e-161 cvfB S protein conserved in bacteria
NIPEHPHG_00239 8.5e-94
NIPEHPHG_00240 2.8e-171
NIPEHPHG_00241 1.5e-97 S Sporulation delaying protein SdpA
NIPEHPHG_00242 1.5e-58 K Transcriptional regulator PadR-like family
NIPEHPHG_00243 2e-95
NIPEHPHG_00244 1.4e-44 yitR S Domain of unknown function (DUF3784)
NIPEHPHG_00245 2.2e-311 nprB 3.4.24.28 E Peptidase M4
NIPEHPHG_00246 8.4e-159 yitS S protein conserved in bacteria
NIPEHPHG_00247 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
NIPEHPHG_00248 1.9e-72 ipi S Intracellular proteinase inhibitor
NIPEHPHG_00249 1.2e-17 S Protein of unknown function (DUF3813)
NIPEHPHG_00250 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
NIPEHPHG_00251 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
NIPEHPHG_00252 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
NIPEHPHG_00253 1.5e-22 pilT S Proteolipid membrane potential modulator
NIPEHPHG_00254 4.3e-272 yitY C D-arabinono-1,4-lactone oxidase
NIPEHPHG_00255 1.7e-88 norB G Major Facilitator Superfamily
NIPEHPHG_00256 5.4e-200 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NIPEHPHG_00257 3.1e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NIPEHPHG_00258 2.2e-137 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NIPEHPHG_00259 4.4e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
NIPEHPHG_00260 3.9e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NIPEHPHG_00261 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
NIPEHPHG_00262 3.8e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NIPEHPHG_00263 9.5e-28 yjzC S YjzC-like protein
NIPEHPHG_00264 2.3e-16 yjzD S Protein of unknown function (DUF2929)
NIPEHPHG_00265 6.2e-142 yjaU I carboxylic ester hydrolase activity
NIPEHPHG_00266 7.3e-103 yjaV
NIPEHPHG_00267 1.1e-183 med S Transcriptional activator protein med
NIPEHPHG_00268 7.3e-26 comZ S ComZ
NIPEHPHG_00269 2.7e-22 yjzB
NIPEHPHG_00270 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NIPEHPHG_00271 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NIPEHPHG_00272 7.8e-151 yjaZ O Zn-dependent protease
NIPEHPHG_00273 1.8e-184 appD P Belongs to the ABC transporter superfamily
NIPEHPHG_00274 6.5e-187 appF E Belongs to the ABC transporter superfamily
NIPEHPHG_00275 1.6e-251 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
NIPEHPHG_00276 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NIPEHPHG_00277 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NIPEHPHG_00278 5e-147 yjbA S Belongs to the UPF0736 family
NIPEHPHG_00279 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NIPEHPHG_00280 0.0 oppA E ABC transporter substrate-binding protein
NIPEHPHG_00281 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NIPEHPHG_00282 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NIPEHPHG_00283 3e-198 oppD P Belongs to the ABC transporter superfamily
NIPEHPHG_00284 5.5e-172 oppF E Belongs to the ABC transporter superfamily
NIPEHPHG_00285 8.6e-196 yjbB EGP Major Facilitator Superfamily
NIPEHPHG_00286 6.9e-104 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NIPEHPHG_00287 2.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NIPEHPHG_00288 6e-112 yjbE P Integral membrane protein TerC family
NIPEHPHG_00289 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NIPEHPHG_00290 2.3e-223 yjbF S Competence protein
NIPEHPHG_00291 0.0 pepF E oligoendopeptidase F
NIPEHPHG_00292 1.8e-20
NIPEHPHG_00294 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NIPEHPHG_00295 3.7e-72 yjbI S Bacterial-like globin
NIPEHPHG_00296 1.5e-87 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NIPEHPHG_00297 2.4e-101 yjbK S protein conserved in bacteria
NIPEHPHG_00298 7.1e-62 yjbL S Belongs to the UPF0738 family
NIPEHPHG_00299 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
NIPEHPHG_00300 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NIPEHPHG_00301 9.5e-161 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NIPEHPHG_00302 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NIPEHPHG_00303 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NIPEHPHG_00304 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NIPEHPHG_00305 3.8e-108 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
NIPEHPHG_00306 7.2e-219 thiO 1.4.3.19 E Glycine oxidase
NIPEHPHG_00307 3e-30 thiS H thiamine diphosphate biosynthetic process
NIPEHPHG_00308 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NIPEHPHG_00309 6e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NIPEHPHG_00310 5.3e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NIPEHPHG_00311 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NIPEHPHG_00312 5.9e-54 yjbX S Spore coat protein
NIPEHPHG_00313 5.2e-83 cotZ S Spore coat protein
NIPEHPHG_00314 3.4e-96 cotY S Spore coat protein Z
NIPEHPHG_00315 6.4e-77 cotX S Spore Coat Protein X and V domain
NIPEHPHG_00316 3e-32 cotW
NIPEHPHG_00317 2.3e-55 cotV S Spore Coat Protein X and V domain
NIPEHPHG_00318 8.7e-57 yjcA S Protein of unknown function (DUF1360)
NIPEHPHG_00321 2.9e-38 spoVIF S Stage VI sporulation protein F
NIPEHPHG_00322 0.0 yjcD 3.6.4.12 L DNA helicase
NIPEHPHG_00323 1.7e-38
NIPEHPHG_00324 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NIPEHPHG_00325 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
NIPEHPHG_00326 1.8e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
NIPEHPHG_00327 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NIPEHPHG_00328 2.9e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NIPEHPHG_00329 3.7e-99 rimJ 2.3.1.128 J Alanine acetyltransferase
NIPEHPHG_00330 1.1e-212 yjcL S Protein of unknown function (DUF819)
NIPEHPHG_00333 2.1e-190 S Putative amidase domain
NIPEHPHG_00334 2.6e-44 yjcN
NIPEHPHG_00337 8.5e-81 L Transposase
NIPEHPHG_00338 1.6e-72 yjcP
NIPEHPHG_00339 4.1e-49 S YjcQ protein
NIPEHPHG_00340 1.1e-92 yqaS L DNA packaging
NIPEHPHG_00341 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
NIPEHPHG_00342 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
NIPEHPHG_00344 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
NIPEHPHG_00345 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
NIPEHPHG_00346 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
NIPEHPHG_00347 4.8e-51 yjdF S Protein of unknown function (DUF2992)
NIPEHPHG_00348 2.5e-94 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
NIPEHPHG_00350 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NIPEHPHG_00351 4.2e-29 S Domain of unknown function (DUF4177)
NIPEHPHG_00352 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
NIPEHPHG_00353 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NIPEHPHG_00355 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
NIPEHPHG_00356 5.5e-83 S Protein of unknown function (DUF2690)
NIPEHPHG_00357 3.6e-21 yjfB S Putative motility protein
NIPEHPHG_00358 1.6e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
NIPEHPHG_00359 1.2e-45 T PhoQ Sensor
NIPEHPHG_00360 8.9e-104 yjgB S Domain of unknown function (DUF4309)
NIPEHPHG_00361 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NIPEHPHG_00362 4.3e-95 yjgD S Protein of unknown function (DUF1641)
NIPEHPHG_00363 8.7e-07 S Domain of unknown function (DUF4352)
NIPEHPHG_00364 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
NIPEHPHG_00366 3.8e-226 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
NIPEHPHG_00367 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NIPEHPHG_00368 8.2e-30
NIPEHPHG_00369 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NIPEHPHG_00370 1.9e-122 ybbM S transport system, permease component
NIPEHPHG_00371 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
NIPEHPHG_00372 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
NIPEHPHG_00373 2.8e-93 yjlB S Cupin domain
NIPEHPHG_00374 7.1e-66 yjlC S Protein of unknown function (DUF1641)
NIPEHPHG_00375 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
NIPEHPHG_00376 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
NIPEHPHG_00377 5.8e-250 yjmB G symporter YjmB
NIPEHPHG_00378 3e-195 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
NIPEHPHG_00379 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
NIPEHPHG_00380 4.7e-215 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
NIPEHPHG_00381 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NIPEHPHG_00382 3.7e-227 exuT G Sugar (and other) transporter
NIPEHPHG_00383 2.3e-184 exuR K transcriptional
NIPEHPHG_00384 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
NIPEHPHG_00385 2e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
NIPEHPHG_00386 4.3e-130 MA20_18170 S membrane transporter protein
NIPEHPHG_00387 3.3e-80 yjoA S DinB family
NIPEHPHG_00388 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
NIPEHPHG_00389 2.1e-213 S response regulator aspartate phosphatase
NIPEHPHG_00391 6.3e-41 S YCII-related domain
NIPEHPHG_00392 9.1e-170 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
NIPEHPHG_00393 2.1e-61 yjqA S Bacterial PH domain
NIPEHPHG_00394 4.2e-112 yjqB S Pfam:DUF867
NIPEHPHG_00395 4.4e-160 ydbD P Catalase
NIPEHPHG_00396 1.6e-111 xkdA E IrrE N-terminal-like domain
NIPEHPHG_00397 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
NIPEHPHG_00399 5.9e-157 xkdB K sequence-specific DNA binding
NIPEHPHG_00400 6.4e-119 xkdC L Bacterial dnaA protein
NIPEHPHG_00403 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
NIPEHPHG_00404 4.4e-86 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NIPEHPHG_00405 4.8e-140 xtmA L phage terminase small subunit
NIPEHPHG_00406 9.6e-255 xtmB S phage terminase, large subunit
NIPEHPHG_00407 5.4e-286 yqbA S portal protein
NIPEHPHG_00408 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
NIPEHPHG_00409 5.8e-169 xkdG S Phage capsid family
NIPEHPHG_00410 5.5e-65 yqbG S Protein of unknown function (DUF3199)
NIPEHPHG_00411 8.7e-65 yqbH S Domain of unknown function (DUF3599)
NIPEHPHG_00412 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
NIPEHPHG_00413 1.9e-77 xkdJ
NIPEHPHG_00414 2.5e-256 xkdK S Phage tail sheath C-terminal domain
NIPEHPHG_00415 6.1e-76 xkdM S Phage tail tube protein
NIPEHPHG_00416 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
NIPEHPHG_00417 0.0 xkdO L Transglycosylase SLT domain
NIPEHPHG_00418 3.7e-122 xkdP S Lysin motif
NIPEHPHG_00419 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
NIPEHPHG_00420 2.1e-39 xkdR S Protein of unknown function (DUF2577)
NIPEHPHG_00421 9.6e-71 xkdS S Protein of unknown function (DUF2634)
NIPEHPHG_00422 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NIPEHPHG_00423 4e-104 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
NIPEHPHG_00424 6.7e-41
NIPEHPHG_00425 0.0
NIPEHPHG_00426 2.6e-55 xkdW S XkdW protein
NIPEHPHG_00427 1.7e-23 xkdX
NIPEHPHG_00428 1.2e-154 xepA
NIPEHPHG_00429 2.8e-39 xhlA S Haemolysin XhlA
NIPEHPHG_00430 9.3e-40 xhlB S SPP1 phage holin
NIPEHPHG_00431 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NIPEHPHG_00432 6.7e-23 spoIISB S Stage II sporulation protein SB
NIPEHPHG_00433 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
NIPEHPHG_00434 5.8e-175 pit P phosphate transporter
NIPEHPHG_00435 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
NIPEHPHG_00436 9.4e-242 steT E amino acid
NIPEHPHG_00437 7.2e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
NIPEHPHG_00439 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NIPEHPHG_00440 1.3e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NIPEHPHG_00442 8.5e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NIPEHPHG_00443 1e-137 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
NIPEHPHG_00444 7.9e-154 dppA E D-aminopeptidase
NIPEHPHG_00445 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NIPEHPHG_00446 3.9e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NIPEHPHG_00447 3.4e-191 dppD P Belongs to the ABC transporter superfamily
NIPEHPHG_00448 0.0 dppE E ABC transporter substrate-binding protein
NIPEHPHG_00450 8.1e-179 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
NIPEHPHG_00451 3.2e-203 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NIPEHPHG_00452 5.3e-172 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NIPEHPHG_00453 7.7e-188 ykfD E Belongs to the ABC transporter superfamily
NIPEHPHG_00454 7.4e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
NIPEHPHG_00455 5.3e-161 ykgA E Amidinotransferase
NIPEHPHG_00456 1.5e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
NIPEHPHG_00457 1e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NIPEHPHG_00458 1e-07
NIPEHPHG_00459 5.4e-130 ykjA S Protein of unknown function (DUF421)
NIPEHPHG_00460 1e-98 ykkA S Protein of unknown function (DUF664)
NIPEHPHG_00461 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NIPEHPHG_00462 3.5e-55 ykkC P Multidrug resistance protein
NIPEHPHG_00463 1.1e-50 ykkD P Multidrug resistance protein
NIPEHPHG_00464 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NIPEHPHG_00465 1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NIPEHPHG_00466 2.5e-228 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NIPEHPHG_00467 1.3e-70 ohrA O Organic hydroperoxide resistance protein
NIPEHPHG_00468 3.9e-75 ohrR K COG1846 Transcriptional regulators
NIPEHPHG_00469 8.4e-72 ohrB O Organic hydroperoxide resistance protein
NIPEHPHG_00471 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
NIPEHPHG_00472 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NIPEHPHG_00473 1.7e-176 isp O Belongs to the peptidase S8 family
NIPEHPHG_00474 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NIPEHPHG_00475 1.8e-136 ykoC P Cobalt transport protein
NIPEHPHG_00476 4.6e-311 P ABC transporter, ATP-binding protein
NIPEHPHG_00477 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
NIPEHPHG_00478 7.9e-111 ykoF S YKOF-related Family
NIPEHPHG_00479 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NIPEHPHG_00480 9.4e-245 ykoH 2.7.13.3 T Histidine kinase
NIPEHPHG_00481 1.1e-113 ykoI S Peptidase propeptide and YPEB domain
NIPEHPHG_00482 4.4e-86 ykoJ S Peptidase propeptide and YPEB domain
NIPEHPHG_00485 2.2e-222 mgtE P Acts as a magnesium transporter
NIPEHPHG_00486 1.4e-53 tnrA K transcriptional
NIPEHPHG_00487 5.9e-18
NIPEHPHG_00488 6.9e-26 ykoL
NIPEHPHG_00489 1.3e-81 mhqR K transcriptional
NIPEHPHG_00490 2.3e-220 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
NIPEHPHG_00491 3.7e-99 ykoP G polysaccharide deacetylase
NIPEHPHG_00492 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
NIPEHPHG_00493 0.0 ykoS
NIPEHPHG_00494 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NIPEHPHG_00495 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
NIPEHPHG_00496 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NIPEHPHG_00497 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
NIPEHPHG_00498 1.4e-116 ykoX S membrane-associated protein
NIPEHPHG_00499 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NIPEHPHG_00500 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NIPEHPHG_00501 8.2e-117 rsgI S Anti-sigma factor N-terminus
NIPEHPHG_00502 1.9e-26 sspD S small acid-soluble spore protein
NIPEHPHG_00503 1.5e-124 ykrK S Domain of unknown function (DUF1836)
NIPEHPHG_00504 7e-156 htpX O Belongs to the peptidase M48B family
NIPEHPHG_00505 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
NIPEHPHG_00506 1.2e-10 ydfR S Protein of unknown function (DUF421)
NIPEHPHG_00507 4.5e-22 ykzE
NIPEHPHG_00508 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
NIPEHPHG_00509 0.0 kinE 2.7.13.3 T Histidine kinase
NIPEHPHG_00510 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NIPEHPHG_00512 3.3e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NIPEHPHG_00513 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NIPEHPHG_00514 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NIPEHPHG_00515 8e-232 mtnE 2.6.1.83 E Aminotransferase
NIPEHPHG_00516 4.1e-231 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NIPEHPHG_00517 7.5e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NIPEHPHG_00518 7.2e-115 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NIPEHPHG_00519 1.3e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NIPEHPHG_00520 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
NIPEHPHG_00521 6.4e-09 S Spo0E like sporulation regulatory protein
NIPEHPHG_00522 1.4e-64 eag
NIPEHPHG_00523 2.5e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
NIPEHPHG_00524 1.3e-75 ykvE K transcriptional
NIPEHPHG_00525 1.6e-124 motB N Flagellar motor protein
NIPEHPHG_00526 2.7e-138 motA N flagellar motor
NIPEHPHG_00527 0.0 clpE O Belongs to the ClpA ClpB family
NIPEHPHG_00528 8.7e-182 ykvI S membrane
NIPEHPHG_00529 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NIPEHPHG_00530 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
NIPEHPHG_00531 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NIPEHPHG_00532 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NIPEHPHG_00533 2e-61 ykvN K Transcriptional regulator
NIPEHPHG_00534 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
NIPEHPHG_00535 4e-217 ykvP 3.5.1.28 M Glycosyl transferases group 1
NIPEHPHG_00536 1.2e-35 3.5.1.104 M LysM domain
NIPEHPHG_00537 8.5e-133 G Glycosyl hydrolases family 18
NIPEHPHG_00538 5.6e-46 ykvR S Protein of unknown function (DUF3219)
NIPEHPHG_00539 6e-25 ykvS S protein conserved in bacteria
NIPEHPHG_00540 2.8e-28
NIPEHPHG_00541 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
NIPEHPHG_00542 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NIPEHPHG_00543 4.9e-90 stoA CO thiol-disulfide
NIPEHPHG_00544 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NIPEHPHG_00545 3.8e-09
NIPEHPHG_00546 8.7e-209 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NIPEHPHG_00548 9.8e-180 ykvZ 5.1.1.1 K Transcriptional regulator
NIPEHPHG_00550 4.5e-128 glcT K antiterminator
NIPEHPHG_00551 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NIPEHPHG_00552 2.1e-39 ptsH G phosphocarrier protein HPr
NIPEHPHG_00553 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NIPEHPHG_00554 7.2e-39 splA S Transcriptional regulator
NIPEHPHG_00555 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
NIPEHPHG_00556 1.2e-131 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NIPEHPHG_00557 2e-264 mcpC NT chemotaxis protein
NIPEHPHG_00558 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NIPEHPHG_00559 8e-124 ykwD J protein with SCP PR1 domains
NIPEHPHG_00560 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
NIPEHPHG_00561 0.0 pilS 2.7.13.3 T Histidine kinase
NIPEHPHG_00562 8e-224 patA 2.6.1.1 E Aminotransferase
NIPEHPHG_00563 2.2e-15
NIPEHPHG_00564 1.6e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
NIPEHPHG_00565 1.7e-84 ykyB S YkyB-like protein
NIPEHPHG_00566 1.6e-238 ykuC EGP Major facilitator Superfamily
NIPEHPHG_00567 4.6e-88 ykuD S protein conserved in bacteria
NIPEHPHG_00568 9.4e-166 ykuE S Metallophosphoesterase
NIPEHPHG_00569 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NIPEHPHG_00570 0.0 3.2.1.132 M Putative peptidoglycan binding domain
NIPEHPHG_00571 1.7e-93 M Peptidoglycan-binding domain 1 protein
NIPEHPHG_00573 5.2e-234 ykuI T Diguanylate phosphodiesterase
NIPEHPHG_00574 3.9e-37 ykuJ S protein conserved in bacteria
NIPEHPHG_00575 4.4e-94 ykuK S Ribonuclease H-like
NIPEHPHG_00576 3.9e-27 ykzF S Antirepressor AbbA
NIPEHPHG_00577 1.6e-76 ykuL S CBS domain
NIPEHPHG_00578 3.5e-168 ccpC K Transcriptional regulator
NIPEHPHG_00579 5.7e-88 fld C Flavodoxin domain
NIPEHPHG_00580 3.2e-177 ykuO
NIPEHPHG_00581 3.2e-80 fld C Flavodoxin
NIPEHPHG_00582 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NIPEHPHG_00583 5.8e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NIPEHPHG_00584 9e-37 ykuS S Belongs to the UPF0180 family
NIPEHPHG_00585 8.8e-142 ykuT M Mechanosensitive ion channel
NIPEHPHG_00586 3.9e-101 ykuU O Alkyl hydroperoxide reductase
NIPEHPHG_00587 4.4e-82 ykuV CO thiol-disulfide
NIPEHPHG_00588 5.8e-95 rok K Repressor of ComK
NIPEHPHG_00589 2.9e-147 yknT
NIPEHPHG_00590 3.9e-110 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NIPEHPHG_00591 5.3e-192 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NIPEHPHG_00592 8.1e-246 moeA 2.10.1.1 H molybdopterin
NIPEHPHG_00593 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
NIPEHPHG_00594 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
NIPEHPHG_00595 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NIPEHPHG_00596 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
NIPEHPHG_00597 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
NIPEHPHG_00598 1e-117 yknW S Yip1 domain
NIPEHPHG_00599 3e-159 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIPEHPHG_00600 2.5e-124 macB V ABC transporter, ATP-binding protein
NIPEHPHG_00601 2.1e-211 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
NIPEHPHG_00602 3.1e-136 fruR K Transcriptional regulator
NIPEHPHG_00603 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
NIPEHPHG_00604 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NIPEHPHG_00605 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NIPEHPHG_00606 8.1e-39 ykoA
NIPEHPHG_00607 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NIPEHPHG_00608 1.5e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NIPEHPHG_00609 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
NIPEHPHG_00610 1.1e-12 S Uncharacterized protein YkpC
NIPEHPHG_00611 7.7e-183 mreB D Rod-share determining protein MreBH
NIPEHPHG_00612 1.5e-43 abrB K of stationary sporulation gene expression
NIPEHPHG_00613 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
NIPEHPHG_00614 1.6e-162 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
NIPEHPHG_00615 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
NIPEHPHG_00616 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NIPEHPHG_00617 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NIPEHPHG_00618 8.2e-31 ykzG S Belongs to the UPF0356 family
NIPEHPHG_00619 1.4e-147 ykrA S hydrolases of the HAD superfamily
NIPEHPHG_00620 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NIPEHPHG_00622 2e-115 recN L Putative cell-wall binding lipoprotein
NIPEHPHG_00623 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NIPEHPHG_00624 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NIPEHPHG_00625 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NIPEHPHG_00626 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NIPEHPHG_00627 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
NIPEHPHG_00628 3.5e-277 speA 4.1.1.19 E Arginine
NIPEHPHG_00629 1.6e-42 yktA S Belongs to the UPF0223 family
NIPEHPHG_00630 7.1e-118 yktB S Belongs to the UPF0637 family
NIPEHPHG_00631 7.1e-26 ykzI
NIPEHPHG_00632 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
NIPEHPHG_00633 6.9e-78 ykzC S Acetyltransferase (GNAT) family
NIPEHPHG_00634 6.5e-173 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NIPEHPHG_00635 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
NIPEHPHG_00636 0.0 ylaA
NIPEHPHG_00637 2.7e-42 ylaB
NIPEHPHG_00638 2.7e-91 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
NIPEHPHG_00639 1.2e-11 sigC S Putative zinc-finger
NIPEHPHG_00640 1.8e-38 ylaE
NIPEHPHG_00641 8.2e-22 S Family of unknown function (DUF5325)
NIPEHPHG_00642 0.0 typA T GTP-binding protein TypA
NIPEHPHG_00643 4.2e-47 ylaH S YlaH-like protein
NIPEHPHG_00644 2.5e-32 ylaI S protein conserved in bacteria
NIPEHPHG_00645 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NIPEHPHG_00646 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
NIPEHPHG_00647 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NIPEHPHG_00648 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
NIPEHPHG_00649 8.7e-44 ylaN S Belongs to the UPF0358 family
NIPEHPHG_00650 4.5e-214 ftsW D Belongs to the SEDS family
NIPEHPHG_00651 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NIPEHPHG_00652 2.6e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NIPEHPHG_00653 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NIPEHPHG_00654 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NIPEHPHG_00655 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NIPEHPHG_00656 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NIPEHPHG_00657 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NIPEHPHG_00658 3e-167 ctaG S cytochrome c oxidase
NIPEHPHG_00659 7e-62 ylbA S YugN-like family
NIPEHPHG_00660 2.6e-74 ylbB T COG0517 FOG CBS domain
NIPEHPHG_00661 3e-201 ylbC S protein with SCP PR1 domains
NIPEHPHG_00662 4.1e-63 ylbD S Putative coat protein
NIPEHPHG_00663 6.7e-37 ylbE S YlbE-like protein
NIPEHPHG_00664 1.8e-75 ylbF S Belongs to the UPF0342 family
NIPEHPHG_00665 7.5e-39 ylbG S UPF0298 protein
NIPEHPHG_00666 1.9e-98 rsmD 2.1.1.171 L Methyltransferase
NIPEHPHG_00667 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NIPEHPHG_00668 3.8e-221 ylbJ S Sporulation integral membrane protein YlbJ
NIPEHPHG_00669 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
NIPEHPHG_00670 6.8e-187 ylbL T Belongs to the peptidase S16 family
NIPEHPHG_00671 2.8e-235 ylbM S Belongs to the UPF0348 family
NIPEHPHG_00673 1.3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
NIPEHPHG_00674 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NIPEHPHG_00675 6.8e-75 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NIPEHPHG_00676 4e-89 ylbP K n-acetyltransferase
NIPEHPHG_00677 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NIPEHPHG_00678 2.9e-309 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NIPEHPHG_00679 2.9e-78 mraZ K Belongs to the MraZ family
NIPEHPHG_00680 6.6e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NIPEHPHG_00681 3.7e-44 ftsL D Essential cell division protein
NIPEHPHG_00682 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NIPEHPHG_00683 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
NIPEHPHG_00684 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NIPEHPHG_00685 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NIPEHPHG_00686 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NIPEHPHG_00687 5.7e-186 spoVE D Belongs to the SEDS family
NIPEHPHG_00688 2.3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NIPEHPHG_00689 5.3e-167 murB 1.3.1.98 M cell wall formation
NIPEHPHG_00690 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NIPEHPHG_00691 2.4e-103 ylxW S protein conserved in bacteria
NIPEHPHG_00692 1e-102 ylxX S protein conserved in bacteria
NIPEHPHG_00693 6.2e-58 sbp S small basic protein
NIPEHPHG_00694 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NIPEHPHG_00695 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NIPEHPHG_00696 0.0 bpr O COG1404 Subtilisin-like serine proteases
NIPEHPHG_00697 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NIPEHPHG_00698 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NIPEHPHG_00699 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NIPEHPHG_00700 1.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NIPEHPHG_00701 1.3e-256 argE 3.5.1.16 E Acetylornithine deacetylase
NIPEHPHG_00702 2.4e-37 ylmC S sporulation protein
NIPEHPHG_00703 1.1e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
NIPEHPHG_00704 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NIPEHPHG_00705 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NIPEHPHG_00706 1.3e-39 yggT S membrane
NIPEHPHG_00707 6.7e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
NIPEHPHG_00708 2.6e-67 divIVA D Cell division initiation protein
NIPEHPHG_00709 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NIPEHPHG_00710 1.3e-63 dksA T COG1734 DnaK suppressor protein
NIPEHPHG_00711 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NIPEHPHG_00712 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NIPEHPHG_00713 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NIPEHPHG_00714 9e-232 pyrP F Xanthine uracil
NIPEHPHG_00715 1.4e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NIPEHPHG_00716 1.7e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NIPEHPHG_00717 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NIPEHPHG_00718 0.0 carB 6.3.5.5 F Belongs to the CarB family
NIPEHPHG_00719 4.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NIPEHPHG_00720 2.9e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NIPEHPHG_00721 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NIPEHPHG_00722 2.9e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NIPEHPHG_00724 3.5e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NIPEHPHG_00725 1.1e-179 cysP P phosphate transporter
NIPEHPHG_00726 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NIPEHPHG_00727 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
NIPEHPHG_00728 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NIPEHPHG_00729 2e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
NIPEHPHG_00730 4.3e-83 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
NIPEHPHG_00731 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NIPEHPHG_00732 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
NIPEHPHG_00733 2.4e-156 yloC S stress-induced protein
NIPEHPHG_00734 1.5e-40 ylzA S Belongs to the UPF0296 family
NIPEHPHG_00735 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NIPEHPHG_00736 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NIPEHPHG_00737 8.8e-226 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NIPEHPHG_00738 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NIPEHPHG_00739 6e-85 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NIPEHPHG_00740 3.8e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NIPEHPHG_00741 2.9e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NIPEHPHG_00742 4.8e-207 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NIPEHPHG_00743 2.4e-141 stp 3.1.3.16 T phosphatase
NIPEHPHG_00744 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NIPEHPHG_00745 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NIPEHPHG_00746 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NIPEHPHG_00747 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
NIPEHPHG_00748 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NIPEHPHG_00749 5.5e-59 asp S protein conserved in bacteria
NIPEHPHG_00750 2.7e-302 yloV S kinase related to dihydroxyacetone kinase
NIPEHPHG_00751 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
NIPEHPHG_00752 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
NIPEHPHG_00753 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NIPEHPHG_00754 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NIPEHPHG_00755 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NIPEHPHG_00756 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NIPEHPHG_00757 6.1e-129 IQ reductase
NIPEHPHG_00758 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NIPEHPHG_00759 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NIPEHPHG_00760 0.0 smc D Required for chromosome condensation and partitioning
NIPEHPHG_00761 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NIPEHPHG_00762 2.9e-87
NIPEHPHG_00763 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NIPEHPHG_00764 6e-236 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NIPEHPHG_00765 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NIPEHPHG_00766 1.2e-36 ylqC S Belongs to the UPF0109 family
NIPEHPHG_00767 1.3e-61 ylqD S YlqD protein
NIPEHPHG_00768 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NIPEHPHG_00769 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NIPEHPHG_00770 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NIPEHPHG_00771 4.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NIPEHPHG_00772 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NIPEHPHG_00773 8.5e-291 ylqG
NIPEHPHG_00774 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
NIPEHPHG_00775 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NIPEHPHG_00776 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NIPEHPHG_00777 1.7e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
NIPEHPHG_00778 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NIPEHPHG_00779 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NIPEHPHG_00780 2.5e-169 xerC L tyrosine recombinase XerC
NIPEHPHG_00781 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NIPEHPHG_00782 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NIPEHPHG_00783 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NIPEHPHG_00784 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NIPEHPHG_00785 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
NIPEHPHG_00786 1.9e-31 fliE N Flagellar hook-basal body
NIPEHPHG_00787 2.4e-255 fliF N The M ring may be actively involved in energy transduction
NIPEHPHG_00788 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NIPEHPHG_00789 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
NIPEHPHG_00790 2.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NIPEHPHG_00791 1.5e-69 fliJ N Flagellar biosynthesis chaperone
NIPEHPHG_00792 7.7e-37 ylxF S MgtE intracellular N domain
NIPEHPHG_00793 1.2e-221 fliK N Flagellar hook-length control protein
NIPEHPHG_00794 1.7e-72 flgD N Flagellar basal body rod modification protein
NIPEHPHG_00795 8.2e-140 flgG N Flagellar basal body rod
NIPEHPHG_00796 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
NIPEHPHG_00797 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NIPEHPHG_00798 6.6e-183 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NIPEHPHG_00799 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
NIPEHPHG_00800 9.3e-97 fliZ N Flagellar biosynthesis protein, FliO
NIPEHPHG_00801 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
NIPEHPHG_00802 2.2e-36 fliQ N Role in flagellar biosynthesis
NIPEHPHG_00803 3.6e-132 fliR N Flagellar biosynthetic protein FliR
NIPEHPHG_00804 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NIPEHPHG_00805 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NIPEHPHG_00806 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
NIPEHPHG_00807 7.5e-158 flhG D Belongs to the ParA family
NIPEHPHG_00808 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NIPEHPHG_00809 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
NIPEHPHG_00810 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
NIPEHPHG_00811 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NIPEHPHG_00812 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NIPEHPHG_00813 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NIPEHPHG_00814 4.3e-78 ylxL
NIPEHPHG_00815 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
NIPEHPHG_00816 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NIPEHPHG_00817 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NIPEHPHG_00818 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NIPEHPHG_00819 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NIPEHPHG_00820 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
NIPEHPHG_00821 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NIPEHPHG_00822 7.7e-233 rasP M zinc metalloprotease
NIPEHPHG_00823 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NIPEHPHG_00824 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NIPEHPHG_00825 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
NIPEHPHG_00826 1.1e-203 nusA K Participates in both transcription termination and antitermination
NIPEHPHG_00827 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
NIPEHPHG_00828 3.1e-47 ylxQ J ribosomal protein
NIPEHPHG_00829 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NIPEHPHG_00830 3e-44 ylxP S protein conserved in bacteria
NIPEHPHG_00831 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NIPEHPHG_00832 1.3e-173 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NIPEHPHG_00833 6.1e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NIPEHPHG_00834 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NIPEHPHG_00835 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NIPEHPHG_00836 4.2e-183 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
NIPEHPHG_00837 4.4e-233 pepR S Belongs to the peptidase M16 family
NIPEHPHG_00838 2.6e-42 ymxH S YlmC YmxH family
NIPEHPHG_00839 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
NIPEHPHG_00840 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NIPEHPHG_00841 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NIPEHPHG_00842 5.9e-222 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NIPEHPHG_00843 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIPEHPHG_00844 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NIPEHPHG_00845 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
NIPEHPHG_00846 4.4e-32 S YlzJ-like protein
NIPEHPHG_00847 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NIPEHPHG_00848 1.4e-133 ymfC K Transcriptional regulator
NIPEHPHG_00849 1.5e-206 ymfD EGP Major facilitator Superfamily
NIPEHPHG_00850 2.9e-235 ymfF S Peptidase M16
NIPEHPHG_00851 1.4e-242 ymfH S zinc protease
NIPEHPHG_00852 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NIPEHPHG_00853 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
NIPEHPHG_00854 2.7e-143 ymfK S Protein of unknown function (DUF3388)
NIPEHPHG_00855 1.9e-124 ymfM S protein conserved in bacteria
NIPEHPHG_00856 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NIPEHPHG_00857 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
NIPEHPHG_00858 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NIPEHPHG_00859 1e-215 pbpX V Beta-lactamase
NIPEHPHG_00860 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
NIPEHPHG_00861 1.9e-152 ymdB S protein conserved in bacteria
NIPEHPHG_00862 1.2e-36 spoVS S Stage V sporulation protein S
NIPEHPHG_00863 2.7e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NIPEHPHG_00864 6.5e-218 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NIPEHPHG_00865 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NIPEHPHG_00866 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
NIPEHPHG_00867 2.2e-88 cotE S Spore coat protein
NIPEHPHG_00868 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NIPEHPHG_00869 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NIPEHPHG_00870 2.3e-70 S Regulatory protein YrvL
NIPEHPHG_00872 1.2e-97 ymcC S Membrane
NIPEHPHG_00873 4.4e-109 pksA K Transcriptional regulator
NIPEHPHG_00874 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
NIPEHPHG_00875 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NIPEHPHG_00877 2.4e-186 pksD Q Acyl transferase domain
NIPEHPHG_00878 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NIPEHPHG_00879 1.4e-37 acpK IQ Phosphopantetheine attachment site
NIPEHPHG_00880 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NIPEHPHG_00881 1.3e-245 pksG 2.3.3.10 I synthase
NIPEHPHG_00882 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
NIPEHPHG_00883 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
NIPEHPHG_00884 0.0 rhiB IQ polyketide synthase
NIPEHPHG_00885 0.0 pfaA Q Polyketide synthase of type I
NIPEHPHG_00886 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
NIPEHPHG_00887 0.0 dhbF IQ polyketide synthase
NIPEHPHG_00888 0.0 pks13 HQ Beta-ketoacyl synthase
NIPEHPHG_00889 2.5e-233 cypA C Cytochrome P450
NIPEHPHG_00890 1.2e-61 ymzB
NIPEHPHG_00891 6.6e-164 ymaE S Metallo-beta-lactamase superfamily
NIPEHPHG_00892 4.6e-252 aprX O Belongs to the peptidase S8 family
NIPEHPHG_00893 2.1e-126 ymaC S Replication protein
NIPEHPHG_00894 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
NIPEHPHG_00895 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
NIPEHPHG_00896 4.9e-51 ebrA P Small Multidrug Resistance protein
NIPEHPHG_00898 2.1e-46 ymaF S YmaF family
NIPEHPHG_00899 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NIPEHPHG_00900 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NIPEHPHG_00901 6.3e-23
NIPEHPHG_00902 4.5e-22 ymzA
NIPEHPHG_00903 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
NIPEHPHG_00904 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NIPEHPHG_00905 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NIPEHPHG_00906 2e-109 ymaB
NIPEHPHG_00907 8e-116 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NIPEHPHG_00908 1.7e-176 spoVK O stage V sporulation protein K
NIPEHPHG_00909 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NIPEHPHG_00910 3.3e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NIPEHPHG_00911 1.1e-68 glnR K transcriptional
NIPEHPHG_00912 7e-261 glnA 6.3.1.2 E glutamine synthetase
NIPEHPHG_00913 1.2e-131 L Belongs to the 'phage' integrase family
NIPEHPHG_00914 2.7e-42 E Zn peptidase
NIPEHPHG_00915 5.3e-25 K Helix-turn-helix XRE-family like proteins
NIPEHPHG_00917 3.6e-23
NIPEHPHG_00919 8.4e-82 S Phage regulatory protein Rha (Phage_pRha)
NIPEHPHG_00920 4.1e-12
NIPEHPHG_00922 9e-83 L DnaD domain protein
NIPEHPHG_00923 3.9e-25 S Loader and inhibitor of phage G40P
NIPEHPHG_00924 2e-170 dnaB 3.6.4.12 L replicative DNA helicase
NIPEHPHG_00925 1.2e-21
NIPEHPHG_00926 6.9e-19 S Phage-like element PBSX protein XtrA
NIPEHPHG_00928 3.5e-50 wecC 1.1.1.336 M ArpU family transcriptional regulator
NIPEHPHG_00932 9.8e-87 yrdC 3.5.1.19 Q Isochorismatase family
NIPEHPHG_00935 6.8e-79 L phage terminase small subunit
NIPEHPHG_00936 8.6e-304 S Terminase
NIPEHPHG_00937 2.2e-174 S Phage portal protein
NIPEHPHG_00938 4.4e-80 S peptidase activity
NIPEHPHG_00939 5.6e-154 gp36 S capsid protein
NIPEHPHG_00940 1.7e-20
NIPEHPHG_00941 1.7e-37 S Phage gp6-like head-tail connector protein
NIPEHPHG_00942 6.1e-38 S Phage head-tail joining protein
NIPEHPHG_00943 2.3e-50 S Bacteriophage HK97-gp10, putative tail-component
NIPEHPHG_00945 8.1e-79 S Phage tail tube protein
NIPEHPHG_00948 0.0 D phage tail tape measure protein
NIPEHPHG_00949 5.8e-112 S Phage tail protein
NIPEHPHG_00950 1.1e-221 NU Prophage endopeptidase tail
NIPEHPHG_00951 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
NIPEHPHG_00952 2.5e-104 S Domain of unknown function (DUF2479)
NIPEHPHG_00955 2.1e-57 S Bacteriophage holin family
NIPEHPHG_00956 5.4e-125 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NIPEHPHG_00957 2.7e-65 S Immunity protein 70
NIPEHPHG_00958 7.7e-177 A Pre-toxin TG
NIPEHPHG_00959 5.6e-110 S aspartate phosphatase
NIPEHPHG_00963 5e-10
NIPEHPHG_00964 2.5e-32
NIPEHPHG_00965 5.8e-39
NIPEHPHG_00966 6.8e-80 G regulation of fungal-type cell wall biogenesis
NIPEHPHG_00967 4.9e-145 ynaC
NIPEHPHG_00968 2e-99 ynaD J Acetyltransferase (GNAT) domain
NIPEHPHG_00969 1.9e-123 ynaE S Domain of unknown function (DUF3885)
NIPEHPHG_00970 6.4e-60 ynaF
NIPEHPHG_00973 1.1e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
NIPEHPHG_00974 2.7e-255 xynT G MFS/sugar transport protein
NIPEHPHG_00975 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
NIPEHPHG_00976 1e-215 xylR GK ROK family
NIPEHPHG_00977 4e-264 xylA 5.3.1.5 G Belongs to the xylose isomerase family
NIPEHPHG_00978 6e-293 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
NIPEHPHG_00979 1.4e-113 yokF 3.1.31.1 L RNA catabolic process
NIPEHPHG_00980 3.5e-247 iolT EGP Major facilitator Superfamily
NIPEHPHG_00981 2.7e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NIPEHPHG_00982 6.3e-84 yncE S Protein of unknown function (DUF2691)
NIPEHPHG_00983 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
NIPEHPHG_00984 5.2e-15
NIPEHPHG_00987 1.2e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NIPEHPHG_00989 1.3e-134 S Domain of unknown function, YrpD
NIPEHPHG_00992 7.9e-25 tatA U protein secretion
NIPEHPHG_00993 1.8e-71
NIPEHPHG_00994 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
NIPEHPHG_00997 5.7e-286 gerAA EG Spore germination protein
NIPEHPHG_00998 4.5e-197 gerAB U Spore germination
NIPEHPHG_00999 4.2e-220 gerLC S Spore germination protein
NIPEHPHG_01000 7.7e-154 yndG S DoxX-like family
NIPEHPHG_01001 2.6e-117 yndH S Domain of unknown function (DUF4166)
NIPEHPHG_01002 0.0 yndJ S YndJ-like protein
NIPEHPHG_01004 8.6e-139 yndL S Replication protein
NIPEHPHG_01005 5.8e-74 yndM S Protein of unknown function (DUF2512)
NIPEHPHG_01006 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NIPEHPHG_01008 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NIPEHPHG_01009 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NIPEHPHG_01010 9.2e-113 yneB L resolvase
NIPEHPHG_01011 1.3e-32 ynzC S UPF0291 protein
NIPEHPHG_01012 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NIPEHPHG_01013 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
NIPEHPHG_01014 1.8e-28 yneF S UPF0154 protein
NIPEHPHG_01015 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
NIPEHPHG_01016 7.1e-127 ccdA O cytochrome c biogenesis protein
NIPEHPHG_01017 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
NIPEHPHG_01018 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
NIPEHPHG_01019 4.2e-74 yneK S Protein of unknown function (DUF2621)
NIPEHPHG_01020 4.1e-65 hspX O Spore coat protein
NIPEHPHG_01021 3.9e-19 sspP S Belongs to the SspP family
NIPEHPHG_01022 2.2e-14 sspO S Belongs to the SspO family
NIPEHPHG_01023 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NIPEHPHG_01024 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NIPEHPHG_01026 3.1e-08 sspN S Small acid-soluble spore protein N family
NIPEHPHG_01027 3.9e-35 tlp S Belongs to the Tlp family
NIPEHPHG_01028 1.2e-73 yneP S Thioesterase-like superfamily
NIPEHPHG_01029 1.3e-53 yneQ
NIPEHPHG_01030 4.1e-49 yneR S Belongs to the HesB IscA family
NIPEHPHG_01031 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NIPEHPHG_01032 6.6e-69 yccU S CoA-binding protein
NIPEHPHG_01033 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NIPEHPHG_01034 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NIPEHPHG_01035 2.3e-12
NIPEHPHG_01036 1.3e-57 ynfC
NIPEHPHG_01037 8.2e-252 agcS E Sodium alanine symporter
NIPEHPHG_01038 2.4e-297 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
NIPEHPHG_01040 3.7e-251 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
NIPEHPHG_01041 4.4e-299 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
NIPEHPHG_01042 2.4e-80 yngA S membrane
NIPEHPHG_01043 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NIPEHPHG_01044 5.5e-104 yngC S membrane-associated protein
NIPEHPHG_01045 1.9e-233 nrnB S phosphohydrolase (DHH superfamily)
NIPEHPHG_01046 6.3e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NIPEHPHG_01047 2.2e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NIPEHPHG_01048 8e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
NIPEHPHG_01049 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
NIPEHPHG_01050 3e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
NIPEHPHG_01051 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NIPEHPHG_01052 4.4e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
NIPEHPHG_01053 1.8e-31 S Family of unknown function (DUF5367)
NIPEHPHG_01055 1.3e-306 yngK T Glycosyl hydrolase-like 10
NIPEHPHG_01056 2.8e-64 yngL S Protein of unknown function (DUF1360)
NIPEHPHG_01057 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
NIPEHPHG_01058 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIPEHPHG_01059 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIPEHPHG_01060 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIPEHPHG_01061 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIPEHPHG_01062 4.3e-275 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
NIPEHPHG_01063 9e-189 yoxA 5.1.3.3 G Aldose 1-epimerase
NIPEHPHG_01064 2.3e-246 yoeA V MATE efflux family protein
NIPEHPHG_01065 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
NIPEHPHG_01067 2.2e-96 L Integrase
NIPEHPHG_01068 3e-34 yoeD G Helix-turn-helix domain
NIPEHPHG_01069 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NIPEHPHG_01070 2.5e-158 gltR1 K Transcriptional regulator
NIPEHPHG_01071 5e-187 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NIPEHPHG_01072 2.7e-293 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NIPEHPHG_01073 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
NIPEHPHG_01074 7.8e-155 gltC K Transcriptional regulator
NIPEHPHG_01075 4.1e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NIPEHPHG_01076 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NIPEHPHG_01077 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
NIPEHPHG_01078 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NIPEHPHG_01079 3e-42 yoxC S Bacterial protein of unknown function (DUF948)
NIPEHPHG_01080 3.1e-144 yoxB
NIPEHPHG_01081 7.5e-97 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NIPEHPHG_01082 6.2e-235 yoaB EGP Major facilitator Superfamily
NIPEHPHG_01083 1e-284 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
NIPEHPHG_01084 1.7e-190 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIPEHPHG_01085 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NIPEHPHG_01086 1.9e-33 yoaF
NIPEHPHG_01087 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
NIPEHPHG_01088 7e-14
NIPEHPHG_01089 1.5e-38 S Protein of unknown function (DUF4025)
NIPEHPHG_01090 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
NIPEHPHG_01091 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
NIPEHPHG_01092 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
NIPEHPHG_01093 2.3e-111 yoaK S Membrane
NIPEHPHG_01094 2.5e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
NIPEHPHG_01095 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
NIPEHPHG_01097 3.8e-234 oxdC 4.1.1.2 G Oxalate decarboxylase
NIPEHPHG_01099 1.9e-146 yoaP 3.1.3.18 K YoaP-like
NIPEHPHG_01100 1.2e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
NIPEHPHG_01101 4.1e-89
NIPEHPHG_01102 2.4e-172 yoaR V vancomycin resistance protein
NIPEHPHG_01103 4.3e-75 yoaS S Protein of unknown function (DUF2975)
NIPEHPHG_01104 4.2e-37 yozG K Transcriptional regulator
NIPEHPHG_01105 1.1e-149 yoaT S Protein of unknown function (DUF817)
NIPEHPHG_01106 8.6e-159 yoaU K LysR substrate binding domain
NIPEHPHG_01107 6e-160 yijE EG EamA-like transporter family
NIPEHPHG_01108 3.7e-78 yoaW
NIPEHPHG_01109 1.1e-118 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
NIPEHPHG_01110 2.3e-170 bla 3.5.2.6 V beta-lactamase
NIPEHPHG_01114 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
NIPEHPHG_01115 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
NIPEHPHG_01116 1.4e-37 S TM2 domain
NIPEHPHG_01117 5.7e-58 K Helix-turn-helix
NIPEHPHG_01119 1.6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
NIPEHPHG_01120 6.6e-127 yoqW S Belongs to the SOS response-associated peptidase family
NIPEHPHG_01121 1.8e-178 yobF
NIPEHPHG_01126 1.7e-207 S aspartate phosphatase
NIPEHPHG_01128 1.2e-123 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NIPEHPHG_01129 1.4e-59 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NIPEHPHG_01130 2.6e-38 S YolD-like protein
NIPEHPHG_01131 1.2e-49
NIPEHPHG_01132 0.0 K Psort location Cytoplasmic, score
NIPEHPHG_01133 2.7e-157 yobJ
NIPEHPHG_01134 3e-86 S SMI1-KNR4 cell-wall
NIPEHPHG_01135 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NIPEHPHG_01136 7.9e-105 yokH G SMI1 / KNR4 family
NIPEHPHG_01137 9.5e-280 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
NIPEHPHG_01138 0.0 yobO M Pectate lyase superfamily protein
NIPEHPHG_01139 9.9e-55 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
NIPEHPHG_01140 1e-136 yobQ K helix_turn_helix, arabinose operon control protein
NIPEHPHG_01141 2.5e-143 yobR 2.3.1.1 J FR47-like protein
NIPEHPHG_01142 3e-99 yobS K Transcriptional regulator
NIPEHPHG_01143 4.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
NIPEHPHG_01144 1.5e-88 yobU K Bacterial transcription activator, effector binding domain
NIPEHPHG_01145 9e-178 yobV K WYL domain
NIPEHPHG_01146 2.5e-95 yobW
NIPEHPHG_01147 1e-51 czrA K transcriptional
NIPEHPHG_01148 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NIPEHPHG_01149 1.5e-92 yozB S membrane
NIPEHPHG_01150 2.2e-145
NIPEHPHG_01151 1.9e-94 yocC
NIPEHPHG_01152 6.9e-189 yocD 3.4.17.13 V peptidase S66
NIPEHPHG_01153 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NIPEHPHG_01154 3.2e-198 desK 2.7.13.3 T Histidine kinase
NIPEHPHG_01155 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NIPEHPHG_01156 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
NIPEHPHG_01157 0.0 recQ 3.6.4.12 L DNA helicase
NIPEHPHG_01158 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NIPEHPHG_01159 3.3e-83 dksA T general stress protein
NIPEHPHG_01160 6.4e-54 yocL
NIPEHPHG_01161 6.6e-34
NIPEHPHG_01162 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
NIPEHPHG_01163 1.1e-40 yozN
NIPEHPHG_01164 1.9e-36 yocN
NIPEHPHG_01165 4.2e-56 yozO S Bacterial PH domain
NIPEHPHG_01166 2.7e-31 yozC
NIPEHPHG_01167 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
NIPEHPHG_01168 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
NIPEHPHG_01169 5.4e-166 sodA 1.15.1.1 P Superoxide dismutase
NIPEHPHG_01170 3.4e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NIPEHPHG_01171 5.1e-168 yocS S -transporter
NIPEHPHG_01172 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NIPEHPHG_01173 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NIPEHPHG_01174 0.0 yojO P Von Willebrand factor
NIPEHPHG_01175 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
NIPEHPHG_01176 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NIPEHPHG_01177 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NIPEHPHG_01178 1.8e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
NIPEHPHG_01179 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NIPEHPHG_01181 4.2e-245 norM V Multidrug efflux pump
NIPEHPHG_01182 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NIPEHPHG_01183 2.1e-125 yojG S deacetylase
NIPEHPHG_01184 2.2e-60 yojF S Protein of unknown function (DUF1806)
NIPEHPHG_01185 1.5e-43
NIPEHPHG_01186 3.5e-163 rarD S -transporter
NIPEHPHG_01187 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
NIPEHPHG_01188 3.4e-09
NIPEHPHG_01189 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
NIPEHPHG_01190 3.8e-66 yodA S tautomerase
NIPEHPHG_01191 1.7e-57 yodB K transcriptional
NIPEHPHG_01192 4.8e-108 yodC C nitroreductase
NIPEHPHG_01193 3.8e-113 mhqD S Carboxylesterase
NIPEHPHG_01194 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
NIPEHPHG_01195 6.2e-28 S Protein of unknown function (DUF3311)
NIPEHPHG_01196 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NIPEHPHG_01197 1.9e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
NIPEHPHG_01198 1.7e-128 yodH Q Methyltransferase
NIPEHPHG_01199 5.2e-24 yodI
NIPEHPHG_01200 2.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NIPEHPHG_01201 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
NIPEHPHG_01202 5.3e-09
NIPEHPHG_01203 3.6e-54 yodL S YodL-like
NIPEHPHG_01204 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
NIPEHPHG_01205 2.8e-24 yozD S YozD-like protein
NIPEHPHG_01207 1.4e-124 yodN
NIPEHPHG_01208 1.4e-36 yozE S Belongs to the UPF0346 family
NIPEHPHG_01209 2.9e-47 yokU S YokU-like protein, putative antitoxin
NIPEHPHG_01210 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
NIPEHPHG_01211 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
NIPEHPHG_01212 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
NIPEHPHG_01213 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NIPEHPHG_01214 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NIPEHPHG_01215 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NIPEHPHG_01218 2.9e-145 yiiD K acetyltransferase
NIPEHPHG_01219 1e-256 cgeD M maturation of the outermost layer of the spore
NIPEHPHG_01220 3.5e-38 cgeC
NIPEHPHG_01221 1.2e-65 cgeA
NIPEHPHG_01222 3.3e-188 cgeB S Spore maturation protein
NIPEHPHG_01223 3.6e-213 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
NIPEHPHG_01224 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
NIPEHPHG_01225 1.4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NIPEHPHG_01226 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NIPEHPHG_01227 1.6e-70 ypoP K transcriptional
NIPEHPHG_01228 2.6e-223 mepA V MATE efflux family protein
NIPEHPHG_01229 5.5e-29 ypmT S Uncharacterized ympT
NIPEHPHG_01230 5e-99 ypmS S protein conserved in bacteria
NIPEHPHG_01231 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
NIPEHPHG_01232 3.2e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NIPEHPHG_01233 3.1e-40 ypmP S Protein of unknown function (DUF2535)
NIPEHPHG_01234 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NIPEHPHG_01235 1.6e-185 pspF K Transcriptional regulator
NIPEHPHG_01236 4.2e-110 hlyIII S protein, Hemolysin III
NIPEHPHG_01237 7.4e-112 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NIPEHPHG_01238 7.9e-96 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NIPEHPHG_01239 4.3e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NIPEHPHG_01240 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NIPEHPHG_01241 7.8e-114 ypjP S YpjP-like protein
NIPEHPHG_01242 1.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
NIPEHPHG_01243 1.7e-75 yphP S Belongs to the UPF0403 family
NIPEHPHG_01244 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NIPEHPHG_01245 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
NIPEHPHG_01246 3.1e-110 ypgQ S phosphohydrolase
NIPEHPHG_01247 2.3e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
NIPEHPHG_01248 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NIPEHPHG_01249 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NIPEHPHG_01250 7.9e-31 cspD K Cold-shock protein
NIPEHPHG_01251 3.8e-16 degR
NIPEHPHG_01252 8.1e-31 S Protein of unknown function (DUF2564)
NIPEHPHG_01253 2.6e-27 ypeQ S Zinc-finger
NIPEHPHG_01254 8.9e-127 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
NIPEHPHG_01255 5.4e-107 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NIPEHPHG_01256 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
NIPEHPHG_01258 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
NIPEHPHG_01259 2e-07
NIPEHPHG_01260 1e-38 ypbS S Protein of unknown function (DUF2533)
NIPEHPHG_01261 0.0 ypbR S Dynamin family
NIPEHPHG_01262 5.1e-87 ypbQ S protein conserved in bacteria
NIPEHPHG_01263 4.4e-208 bcsA Q Naringenin-chalcone synthase
NIPEHPHG_01264 1.6e-228 pbuX F xanthine
NIPEHPHG_01265 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NIPEHPHG_01266 4.2e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NIPEHPHG_01267 5e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
NIPEHPHG_01268 7e-104 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
NIPEHPHG_01269 2.9e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
NIPEHPHG_01270 3.9e-187 ptxS K transcriptional
NIPEHPHG_01271 1.7e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NIPEHPHG_01272 7.1e-133 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NIPEHPHG_01273 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
NIPEHPHG_01275 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NIPEHPHG_01276 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NIPEHPHG_01277 3.3e-92 ypsA S Belongs to the UPF0398 family
NIPEHPHG_01278 1.3e-237 yprB L RNase_H superfamily
NIPEHPHG_01279 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NIPEHPHG_01280 1.9e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
NIPEHPHG_01281 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
NIPEHPHG_01282 1.2e-48 yppG S YppG-like protein
NIPEHPHG_01284 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
NIPEHPHG_01287 2.6e-188 yppC S Protein of unknown function (DUF2515)
NIPEHPHG_01288 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NIPEHPHG_01289 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
NIPEHPHG_01290 4.7e-93 ypoC
NIPEHPHG_01291 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NIPEHPHG_01292 5.7e-129 dnaD L DNA replication protein DnaD
NIPEHPHG_01293 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
NIPEHPHG_01294 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NIPEHPHG_01295 3.4e-80 ypmB S protein conserved in bacteria
NIPEHPHG_01296 6.7e-23 ypmA S Protein of unknown function (DUF4264)
NIPEHPHG_01297 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NIPEHPHG_01298 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NIPEHPHG_01299 1.2e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NIPEHPHG_01300 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NIPEHPHG_01301 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NIPEHPHG_01302 4.4e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NIPEHPHG_01303 3.7e-210 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
NIPEHPHG_01304 6.9e-130 bshB1 S proteins, LmbE homologs
NIPEHPHG_01305 6.5e-72 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
NIPEHPHG_01306 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NIPEHPHG_01307 2.6e-55 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
NIPEHPHG_01308 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
NIPEHPHG_01309 6.1e-143 ypjB S sporulation protein
NIPEHPHG_01310 2e-98 ypjA S membrane
NIPEHPHG_01311 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
NIPEHPHG_01312 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
NIPEHPHG_01313 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
NIPEHPHG_01314 8.5e-78 ypiF S Protein of unknown function (DUF2487)
NIPEHPHG_01315 2.8e-99 ypiB S Belongs to the UPF0302 family
NIPEHPHG_01316 4.1e-234 S COG0457 FOG TPR repeat
NIPEHPHG_01317 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NIPEHPHG_01318 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NIPEHPHG_01319 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NIPEHPHG_01320 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NIPEHPHG_01321 4e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NIPEHPHG_01322 6.5e-119 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
NIPEHPHG_01323 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NIPEHPHG_01324 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NIPEHPHG_01325 6.6e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NIPEHPHG_01326 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NIPEHPHG_01327 8.1e-207 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NIPEHPHG_01328 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NIPEHPHG_01329 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
NIPEHPHG_01330 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NIPEHPHG_01331 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NIPEHPHG_01332 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NIPEHPHG_01333 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NIPEHPHG_01334 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NIPEHPHG_01335 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
NIPEHPHG_01336 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NIPEHPHG_01337 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NIPEHPHG_01338 5.4e-138 yphF
NIPEHPHG_01339 1.6e-18 yphE S Protein of unknown function (DUF2768)
NIPEHPHG_01340 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NIPEHPHG_01341 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NIPEHPHG_01342 1.6e-28 ypzH
NIPEHPHG_01343 2.5e-161 seaA S YIEGIA protein
NIPEHPHG_01344 1.3e-102 yphA
NIPEHPHG_01345 1e-07 S YpzI-like protein
NIPEHPHG_01346 4.1e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NIPEHPHG_01347 4.3e-206 rpsA 1.17.7.4 J Ribosomal protein S1
NIPEHPHG_01348 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NIPEHPHG_01349 1.8e-23 S Family of unknown function (DUF5359)
NIPEHPHG_01350 9.2e-113 ypfA M Flagellar protein YcgR
NIPEHPHG_01351 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
NIPEHPHG_01352 4.7e-155 sleB 3.5.1.28 M Spore cortex-lytic enzyme
NIPEHPHG_01353 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
NIPEHPHG_01354 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
NIPEHPHG_01355 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NIPEHPHG_01356 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NIPEHPHG_01357 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
NIPEHPHG_01358 2.8e-81 ypbF S Protein of unknown function (DUF2663)
NIPEHPHG_01359 4.6e-81 ypbE M Lysin motif
NIPEHPHG_01360 2.2e-100 ypbD S metal-dependent membrane protease
NIPEHPHG_01361 3.2e-286 recQ 3.6.4.12 L DNA helicase
NIPEHPHG_01362 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
NIPEHPHG_01363 4.7e-41 fer C Ferredoxin
NIPEHPHG_01364 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NIPEHPHG_01365 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIPEHPHG_01366 9e-136 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NIPEHPHG_01367 6.8e-201 rsiX
NIPEHPHG_01368 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
NIPEHPHG_01369 0.0 resE 2.7.13.3 T Histidine kinase
NIPEHPHG_01370 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NIPEHPHG_01371 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NIPEHPHG_01372 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
NIPEHPHG_01373 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NIPEHPHG_01374 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NIPEHPHG_01375 1.9e-87 spmB S Spore maturation protein
NIPEHPHG_01376 3.5e-103 spmA S Spore maturation protein
NIPEHPHG_01377 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
NIPEHPHG_01378 4e-98 ypuI S Protein of unknown function (DUF3907)
NIPEHPHG_01379 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NIPEHPHG_01380 4.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NIPEHPHG_01381 4.5e-94 ypuF S Domain of unknown function (DUF309)
NIPEHPHG_01382 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NIPEHPHG_01383 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NIPEHPHG_01384 9.8e-230 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NIPEHPHG_01385 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
NIPEHPHG_01386 1.3e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NIPEHPHG_01387 6e-55 ypuD
NIPEHPHG_01388 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NIPEHPHG_01389 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
NIPEHPHG_01390 1.5e-17 S SNARE associated Golgi protein
NIPEHPHG_01393 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NIPEHPHG_01394 1.3e-149 ypuA S Secreted protein
NIPEHPHG_01395 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NIPEHPHG_01396 1.4e-273 spoVAF EG Stage V sporulation protein AF
NIPEHPHG_01397 1.4e-110 spoVAEA S stage V sporulation protein
NIPEHPHG_01398 2.2e-57 spoVAEB S stage V sporulation protein
NIPEHPHG_01399 2.6e-191 spoVAD I Stage V sporulation protein AD
NIPEHPHG_01400 2.3e-78 spoVAC S stage V sporulation protein AC
NIPEHPHG_01401 1e-67 spoVAB S Stage V sporulation protein AB
NIPEHPHG_01402 7.4e-112 spoVAA S Stage V sporulation protein AA
NIPEHPHG_01403 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NIPEHPHG_01404 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NIPEHPHG_01405 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
NIPEHPHG_01406 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
NIPEHPHG_01407 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NIPEHPHG_01408 1.2e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NIPEHPHG_01409 2.6e-166 xerD L recombinase XerD
NIPEHPHG_01410 3.7e-37 S Protein of unknown function (DUF4227)
NIPEHPHG_01411 2.4e-80 fur P Belongs to the Fur family
NIPEHPHG_01412 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NIPEHPHG_01413 2e-32 yqkK
NIPEHPHG_01414 5.5e-242 mleA 1.1.1.38 C malic enzyme
NIPEHPHG_01415 3.1e-235 mleN C Na H antiporter
NIPEHPHG_01416 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
NIPEHPHG_01417 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
NIPEHPHG_01418 4.5e-58 ansR K Transcriptional regulator
NIPEHPHG_01419 3e-223 yqxK 3.6.4.12 L DNA helicase
NIPEHPHG_01420 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
NIPEHPHG_01422 4.4e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
NIPEHPHG_01423 4e-14 yqkE S Protein of unknown function (DUF3886)
NIPEHPHG_01424 2.4e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
NIPEHPHG_01425 9.4e-39 yqkC S Protein of unknown function (DUF2552)
NIPEHPHG_01426 2.8e-54 yqkB S Belongs to the HesB IscA family
NIPEHPHG_01427 4.7e-196 yqkA K GrpB protein
NIPEHPHG_01428 8e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
NIPEHPHG_01429 3.6e-87 yqjY K acetyltransferase
NIPEHPHG_01430 2.2e-49 S YolD-like protein
NIPEHPHG_01431 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NIPEHPHG_01433 5.2e-226 yqjV G Major Facilitator Superfamily
NIPEHPHG_01435 7.2e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NIPEHPHG_01436 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
NIPEHPHG_01437 2.4e-264 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
NIPEHPHG_01438 3.5e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
NIPEHPHG_01439 3.4e-180 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
NIPEHPHG_01440 8.6e-148 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NIPEHPHG_01441 0.0 rocB E arginine degradation protein
NIPEHPHG_01442 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NIPEHPHG_01443 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NIPEHPHG_01444 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NIPEHPHG_01445 1.6e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NIPEHPHG_01446 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NIPEHPHG_01447 3.6e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NIPEHPHG_01448 4.5e-24 yqzJ
NIPEHPHG_01449 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NIPEHPHG_01450 3.6e-142 yqjF S Uncharacterized conserved protein (COG2071)
NIPEHPHG_01451 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
NIPEHPHG_01452 4.4e-291 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NIPEHPHG_01453 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
NIPEHPHG_01455 1.4e-98 yqjB S protein conserved in bacteria
NIPEHPHG_01456 1.1e-175 yqjA S Putative aromatic acid exporter C-terminal domain
NIPEHPHG_01457 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NIPEHPHG_01458 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
NIPEHPHG_01459 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
NIPEHPHG_01460 9.3e-77 yqiW S Belongs to the UPF0403 family
NIPEHPHG_01461 8.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NIPEHPHG_01462 7.9e-208 norA EGP Major facilitator Superfamily
NIPEHPHG_01463 2.6e-152 bmrR K helix_turn_helix, mercury resistance
NIPEHPHG_01464 3.5e-233 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NIPEHPHG_01465 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NIPEHPHG_01466 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NIPEHPHG_01467 3.4e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NIPEHPHG_01468 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
NIPEHPHG_01469 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
NIPEHPHG_01470 7.1e-156 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
NIPEHPHG_01471 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
NIPEHPHG_01472 4e-34 yqzF S Protein of unknown function (DUF2627)
NIPEHPHG_01473 7.1e-164 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NIPEHPHG_01474 5.7e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
NIPEHPHG_01475 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
NIPEHPHG_01476 1.8e-212 mmgC I acyl-CoA dehydrogenase
NIPEHPHG_01477 4.7e-157 hbdA 1.1.1.157 I Dehydrogenase
NIPEHPHG_01478 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
NIPEHPHG_01479 1.8e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NIPEHPHG_01480 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
NIPEHPHG_01481 5.9e-27
NIPEHPHG_01482 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NIPEHPHG_01484 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NIPEHPHG_01485 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
NIPEHPHG_01486 0.0 recN L May be involved in recombinational repair of damaged DNA
NIPEHPHG_01487 1.7e-78 argR K Regulates arginine biosynthesis genes
NIPEHPHG_01488 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
NIPEHPHG_01489 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NIPEHPHG_01490 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NIPEHPHG_01491 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NIPEHPHG_01492 2.2e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NIPEHPHG_01493 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NIPEHPHG_01494 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NIPEHPHG_01495 2.1e-67 yqhY S protein conserved in bacteria
NIPEHPHG_01496 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NIPEHPHG_01497 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NIPEHPHG_01498 9.9e-91 spoIIIAH S SpoIIIAH-like protein
NIPEHPHG_01499 6.9e-103 spoIIIAG S stage III sporulation protein AG
NIPEHPHG_01500 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
NIPEHPHG_01501 1.3e-197 spoIIIAE S stage III sporulation protein AE
NIPEHPHG_01502 2.3e-58 spoIIIAD S Stage III sporulation protein AD
NIPEHPHG_01503 7.6e-29 spoIIIAC S stage III sporulation protein AC
NIPEHPHG_01504 2.9e-85 spoIIIAB S Stage III sporulation protein
NIPEHPHG_01505 1.2e-171 spoIIIAA S stage III sporulation protein AA
NIPEHPHG_01506 7.9e-37 yqhV S Protein of unknown function (DUF2619)
NIPEHPHG_01507 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NIPEHPHG_01508 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NIPEHPHG_01509 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
NIPEHPHG_01510 2.3e-93 yqhR S Conserved membrane protein YqhR
NIPEHPHG_01511 2.1e-174 yqhQ S Protein of unknown function (DUF1385)
NIPEHPHG_01512 2.2e-61 yqhP
NIPEHPHG_01513 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
NIPEHPHG_01514 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NIPEHPHG_01515 5.2e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NIPEHPHG_01516 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
NIPEHPHG_01517 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NIPEHPHG_01518 3.4e-255 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NIPEHPHG_01519 1.8e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
NIPEHPHG_01520 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NIPEHPHG_01521 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
NIPEHPHG_01522 1.2e-24 sinI S Anti-repressor SinI
NIPEHPHG_01523 1e-54 sinR K transcriptional
NIPEHPHG_01524 5.6e-141 tasA S Cell division protein FtsN
NIPEHPHG_01525 2.5e-58 sipW 3.4.21.89 U Signal peptidase
NIPEHPHG_01526 2.8e-113 yqxM
NIPEHPHG_01527 7.3e-54 yqzG S Protein of unknown function (DUF3889)
NIPEHPHG_01528 1.4e-26 yqzE S YqzE-like protein
NIPEHPHG_01529 2.1e-48 comGF U Putative Competence protein ComGF
NIPEHPHG_01530 1.1e-59 comGE
NIPEHPHG_01531 4.4e-71 gspH NU protein transport across the cell outer membrane
NIPEHPHG_01532 1.4e-47 comGC U Required for transformation and DNA binding
NIPEHPHG_01533 1.6e-175 comGB NU COG1459 Type II secretory pathway, component PulF
NIPEHPHG_01534 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NIPEHPHG_01536 7.2e-175 corA P Mg2 transporter protein
NIPEHPHG_01537 5.2e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NIPEHPHG_01538 1.7e-151 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NIPEHPHG_01540 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
NIPEHPHG_01541 1.8e-37 yqgY S Protein of unknown function (DUF2626)
NIPEHPHG_01542 1.9e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
NIPEHPHG_01543 8.9e-23 yqgW S Protein of unknown function (DUF2759)
NIPEHPHG_01544 6.9e-50 yqgV S Thiamine-binding protein
NIPEHPHG_01545 2.7e-199 yqgU
NIPEHPHG_01546 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
NIPEHPHG_01547 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NIPEHPHG_01548 5.2e-181 glcK 2.7.1.2 G Glucokinase
NIPEHPHG_01549 3.1e-33 yqgQ S Protein conserved in bacteria
NIPEHPHG_01550 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
NIPEHPHG_01551 2.5e-09 yqgO
NIPEHPHG_01552 2.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NIPEHPHG_01553 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NIPEHPHG_01554 3.2e-203 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
NIPEHPHG_01556 9.2e-51 yqzD
NIPEHPHG_01557 1.9e-75 yqzC S YceG-like family
NIPEHPHG_01558 9.8e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NIPEHPHG_01559 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NIPEHPHG_01560 1.3e-157 pstA P Phosphate transport system permease
NIPEHPHG_01561 1.3e-160 pstC P probably responsible for the translocation of the substrate across the membrane
NIPEHPHG_01562 5.3e-151 pstS P Phosphate
NIPEHPHG_01563 0.0 pbpA 3.4.16.4 M penicillin-binding protein
NIPEHPHG_01564 2.5e-231 yqgE EGP Major facilitator superfamily
NIPEHPHG_01565 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
NIPEHPHG_01566 4e-73 yqgC S protein conserved in bacteria
NIPEHPHG_01567 8.5e-134 yqgB S Protein of unknown function (DUF1189)
NIPEHPHG_01568 2.2e-75 yqgA
NIPEHPHG_01569 5.2e-47 yqfZ M LysM domain
NIPEHPHG_01570 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NIPEHPHG_01571 4.3e-62 yqfX S membrane
NIPEHPHG_01572 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
NIPEHPHG_01573 1.9e-77 zur P Belongs to the Fur family
NIPEHPHG_01574 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NIPEHPHG_01575 2.1e-36 yqfT S Protein of unknown function (DUF2624)
NIPEHPHG_01576 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NIPEHPHG_01577 1.7e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NIPEHPHG_01578 2.9e-14 yqfQ S YqfQ-like protein
NIPEHPHG_01579 2.6e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NIPEHPHG_01580 5.1e-212 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NIPEHPHG_01581 6.1e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
NIPEHPHG_01582 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
NIPEHPHG_01583 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NIPEHPHG_01584 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NIPEHPHG_01585 4.5e-88 yaiI S Belongs to the UPF0178 family
NIPEHPHG_01586 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NIPEHPHG_01587 4.5e-112 ccpN K CBS domain
NIPEHPHG_01588 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NIPEHPHG_01589 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NIPEHPHG_01590 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
NIPEHPHG_01591 8.4e-19 S YqzL-like protein
NIPEHPHG_01592 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NIPEHPHG_01593 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NIPEHPHG_01594 1.6e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NIPEHPHG_01595 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NIPEHPHG_01596 0.0 yqfF S membrane-associated HD superfamily hydrolase
NIPEHPHG_01598 1.1e-175 phoH T Phosphate starvation-inducible protein PhoH
NIPEHPHG_01599 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
NIPEHPHG_01600 2.7e-45 yqfC S sporulation protein YqfC
NIPEHPHG_01601 6e-25 yqfB
NIPEHPHG_01602 4.3e-122 yqfA S UPF0365 protein
NIPEHPHG_01603 5.4e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
NIPEHPHG_01604 2.5e-61 yqeY S Yqey-like protein
NIPEHPHG_01605 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NIPEHPHG_01606 1.6e-158 yqeW P COG1283 Na phosphate symporter
NIPEHPHG_01607 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
NIPEHPHG_01608 1.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NIPEHPHG_01609 5.4e-175 prmA J Methylates ribosomal protein L11
NIPEHPHG_01610 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NIPEHPHG_01611 0.0 dnaK O Heat shock 70 kDa protein
NIPEHPHG_01612 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NIPEHPHG_01613 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NIPEHPHG_01614 4.8e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
NIPEHPHG_01615 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NIPEHPHG_01616 1e-54 yqxA S Protein of unknown function (DUF3679)
NIPEHPHG_01617 6.9e-223 spoIIP M stage II sporulation protein P
NIPEHPHG_01618 1.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NIPEHPHG_01619 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
NIPEHPHG_01620 1.1e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
NIPEHPHG_01621 4.1e-15 S YqzM-like protein
NIPEHPHG_01622 0.0 comEC S Competence protein ComEC
NIPEHPHG_01623 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
NIPEHPHG_01624 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
NIPEHPHG_01625 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NIPEHPHG_01626 2.9e-139 yqeM Q Methyltransferase
NIPEHPHG_01627 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NIPEHPHG_01628 7.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
NIPEHPHG_01629 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NIPEHPHG_01630 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
NIPEHPHG_01631 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NIPEHPHG_01632 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NIPEHPHG_01633 5.3e-95 yqeG S hydrolase of the HAD superfamily
NIPEHPHG_01635 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
NIPEHPHG_01636 2.1e-137 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NIPEHPHG_01637 4.7e-106 yqeD S SNARE associated Golgi protein
NIPEHPHG_01638 1.2e-171 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
NIPEHPHG_01639 2.3e-133 yqeB
NIPEHPHG_01640 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
NIPEHPHG_01641 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NIPEHPHG_01642 1.4e-281 cisA2 L Recombinase
NIPEHPHG_01643 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
NIPEHPHG_01644 6e-183 arsB 1.20.4.1 P Arsenic resistance protein
NIPEHPHG_01645 2.8e-73 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NIPEHPHG_01646 1.6e-54 arsR K ArsR family transcriptional regulator
NIPEHPHG_01647 1.1e-152 yqcI S YqcI/YcgG family
NIPEHPHG_01648 1.6e-96 S Tetratricopeptide repeat
NIPEHPHG_01651 3.8e-277 A Pre-toxin TG
NIPEHPHG_01652 1.1e-104 S Suppressor of fused protein (SUFU)
NIPEHPHG_01654 5e-60
NIPEHPHG_01656 1.1e-144 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NIPEHPHG_01657 2.6e-68 S Bacteriophage holin family
NIPEHPHG_01658 4.8e-165 xepA
NIPEHPHG_01659 1.3e-23
NIPEHPHG_01660 4.1e-56 xkdW S XkdW protein
NIPEHPHG_01661 2e-221
NIPEHPHG_01662 9.6e-40
NIPEHPHG_01663 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
NIPEHPHG_01664 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NIPEHPHG_01665 9.6e-71 xkdS S Protein of unknown function (DUF2634)
NIPEHPHG_01666 1.8e-38 xkdR S Protein of unknown function (DUF2577)
NIPEHPHG_01667 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
NIPEHPHG_01668 9e-114 xkdP S Lysin motif
NIPEHPHG_01669 0.0 xkdO L Transglycosylase SLT domain
NIPEHPHG_01670 1.8e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
NIPEHPHG_01672 3.6e-76 xkdM S Phage tail tube protein
NIPEHPHG_01673 5.5e-256 xkdK S Phage tail sheath C-terminal domain
NIPEHPHG_01674 3.2e-26
NIPEHPHG_01675 1.4e-77
NIPEHPHG_01676 4.3e-94 S Bacteriophage HK97-gp10, putative tail-component
NIPEHPHG_01677 6.7e-65 yqbH S Domain of unknown function (DUF3599)
NIPEHPHG_01678 2.1e-67 S Protein of unknown function (DUF3199)
NIPEHPHG_01679 3.6e-51 S YqbF, hypothetical protein domain
NIPEHPHG_01680 1.9e-167 xkdG S Phage capsid family
NIPEHPHG_01681 5.1e-128 yqbD 2.1.1.72 L Putative phage serine protease XkdF
NIPEHPHG_01682 2e-115
NIPEHPHG_01683 5.7e-169 S Phage Mu protein F like protein
NIPEHPHG_01684 5.9e-296 yqbA S portal protein
NIPEHPHG_01685 2.4e-253 S phage terminase, large subunit
NIPEHPHG_01686 6.3e-107 yqaS L DNA packaging
NIPEHPHG_01688 6.5e-81 L Transposase
NIPEHPHG_01689 1.6e-166
NIPEHPHG_01690 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
NIPEHPHG_01691 7.2e-74 rusA L Endodeoxyribonuclease RusA
NIPEHPHG_01693 5.9e-168 xkdC L IstB-like ATP binding protein
NIPEHPHG_01694 1e-122 3.1.3.16 L DnaD domain protein
NIPEHPHG_01695 2.5e-155 recT L RecT family
NIPEHPHG_01696 1.5e-180 yqaJ L YqaJ-like viral recombinase domain
NIPEHPHG_01700 1.2e-103
NIPEHPHG_01702 6.5e-37 K Helix-turn-helix XRE-family like proteins
NIPEHPHG_01703 1.1e-56 K sequence-specific DNA binding
NIPEHPHG_01705 1e-101 adk 2.7.4.3 F adenylate kinase activity
NIPEHPHG_01706 1.4e-100 yqaB E IrrE N-terminal-like domain
NIPEHPHG_01707 2.2e-61 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NIPEHPHG_01708 2e-68 psiE S Protein PsiE homolog
NIPEHPHG_01709 9e-237 yrkQ T Histidine kinase
NIPEHPHG_01710 1.1e-127 T Transcriptional regulator
NIPEHPHG_01711 8.2e-224 yrkO P Protein of unknown function (DUF418)
NIPEHPHG_01712 6e-105 yrkN K Acetyltransferase (GNAT) family
NIPEHPHG_01713 1.5e-97 ywrO S Flavodoxin-like fold
NIPEHPHG_01714 2.8e-79 S Protein of unknown function with HXXEE motif
NIPEHPHG_01715 4.3e-117 yrkJ S membrane transporter protein
NIPEHPHG_01716 2.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
NIPEHPHG_01717 2.3e-212 yrkH P Rhodanese Homology Domain
NIPEHPHG_01718 1.7e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
NIPEHPHG_01719 5.1e-84 yrkE O DsrE/DsrF/DrsH-like family
NIPEHPHG_01720 7.8e-39 yrkD S protein conserved in bacteria
NIPEHPHG_01721 2.6e-108 yrkC G Cupin domain
NIPEHPHG_01722 4.8e-151 bltR K helix_turn_helix, mercury resistance
NIPEHPHG_01723 5.9e-22 blt EGP Major facilitator Superfamily
NIPEHPHG_01724 1.1e-167 blt EGP Major facilitator Superfamily
NIPEHPHG_01725 1.4e-83 bltD 2.3.1.57 K FR47-like protein
NIPEHPHG_01726 4.5e-236 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NIPEHPHG_01727 2.1e-17 S YrzO-like protein
NIPEHPHG_01728 1.7e-171 yrdR EG EamA-like transporter family
NIPEHPHG_01729 5.9e-160 yrdQ K Transcriptional regulator
NIPEHPHG_01730 2e-199 trkA P Oxidoreductase
NIPEHPHG_01731 3.5e-158 czcD P COG1230 Co Zn Cd efflux system component
NIPEHPHG_01732 1.3e-66 yodA S tautomerase
NIPEHPHG_01733 2.5e-161 gltR K LysR substrate binding domain
NIPEHPHG_01735 1.1e-226 brnQ E Component of the transport system for branched-chain amino acids
NIPEHPHG_01736 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
NIPEHPHG_01737 2.8e-137 azlC E AzlC protein
NIPEHPHG_01738 2.2e-79 bkdR K helix_turn_helix ASNC type
NIPEHPHG_01739 4.1e-46 yrdF K ribonuclease inhibitor
NIPEHPHG_01740 4.1e-231 cypA C Cytochrome P450
NIPEHPHG_01742 3.1e-101 yrdC 3.5.1.19 Q Isochorismatase family
NIPEHPHG_01743 1.9e-57 S Protein of unknown function (DUF2568)
NIPEHPHG_01744 1.2e-91 yrdA S DinB family
NIPEHPHG_01745 7.6e-168 aadK G Streptomycin adenylyltransferase
NIPEHPHG_01746 1.5e-194 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NIPEHPHG_01747 7.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NIPEHPHG_01748 3e-125 yrpD S Domain of unknown function, YrpD
NIPEHPHG_01750 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
NIPEHPHG_01751 6.3e-96 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
NIPEHPHG_01752 4.5e-188 yrpG C Aldo/keto reductase family
NIPEHPHG_01753 9.5e-226 yraO C Citrate transporter
NIPEHPHG_01754 1.2e-163 yraN K Transcriptional regulator
NIPEHPHG_01755 2.4e-206 yraM S PrpF protein
NIPEHPHG_01757 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
NIPEHPHG_01758 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NIPEHPHG_01759 3.2e-155 S Alpha beta hydrolase
NIPEHPHG_01760 1.7e-60 T sh3 domain protein
NIPEHPHG_01761 2.4e-61 T sh3 domain protein
NIPEHPHG_01762 1.3e-66 E Glyoxalase-like domain
NIPEHPHG_01763 5.3e-37 yraG
NIPEHPHG_01764 6.4e-63 yraF M Spore coat protein
NIPEHPHG_01765 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NIPEHPHG_01766 2.6e-26 yraE
NIPEHPHG_01767 1.1e-49 yraD M Spore coat protein
NIPEHPHG_01768 4.3e-47 yraB K helix_turn_helix, mercury resistance
NIPEHPHG_01769 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
NIPEHPHG_01770 1.9e-200 adhA 1.1.1.1 C alcohol dehydrogenase
NIPEHPHG_01771 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
NIPEHPHG_01772 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NIPEHPHG_01773 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
NIPEHPHG_01774 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
NIPEHPHG_01775 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
NIPEHPHG_01776 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
NIPEHPHG_01777 0.0 levR K PTS system fructose IIA component
NIPEHPHG_01778 1.6e-255 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NIPEHPHG_01779 3.6e-106 yrhP E LysE type translocator
NIPEHPHG_01780 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
NIPEHPHG_01781 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
NIPEHPHG_01782 1.7e-151 rsiV S Protein of unknown function (DUF3298)
NIPEHPHG_01783 0.0 yrhL I Acyltransferase family
NIPEHPHG_01784 1.5e-46 yrhK S YrhK-like protein
NIPEHPHG_01785 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NIPEHPHG_01786 4.8e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
NIPEHPHG_01787 4.5e-97 yrhH Q methyltransferase
NIPEHPHG_01790 1.8e-142 focA P Formate nitrite
NIPEHPHG_01791 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
NIPEHPHG_01792 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NIPEHPHG_01793 1.4e-78 yrhD S Protein of unknown function (DUF1641)
NIPEHPHG_01794 4.6e-35 yrhC S YrhC-like protein
NIPEHPHG_01795 2.6e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NIPEHPHG_01796 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
NIPEHPHG_01797 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NIPEHPHG_01798 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
NIPEHPHG_01799 3.5e-26 yrzA S Protein of unknown function (DUF2536)
NIPEHPHG_01800 4.2e-63 yrrS S Protein of unknown function (DUF1510)
NIPEHPHG_01801 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
NIPEHPHG_01802 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NIPEHPHG_01803 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
NIPEHPHG_01804 2.7e-246 yegQ O COG0826 Collagenase and related proteases
NIPEHPHG_01805 7.8e-174 yegQ O Peptidase U32
NIPEHPHG_01806 5.9e-120 yrrM 2.1.1.104 S O-methyltransferase
NIPEHPHG_01807 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NIPEHPHG_01808 1.2e-45 yrzB S Belongs to the UPF0473 family
NIPEHPHG_01809 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NIPEHPHG_01810 1.7e-41 yrzL S Belongs to the UPF0297 family
NIPEHPHG_01811 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NIPEHPHG_01812 2.7e-170 yrrI S AI-2E family transporter
NIPEHPHG_01813 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NIPEHPHG_01814 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
NIPEHPHG_01815 3.6e-109 gluC P ABC transporter
NIPEHPHG_01816 7.6e-107 glnP P ABC transporter
NIPEHPHG_01817 8e-08 S Protein of unknown function (DUF3918)
NIPEHPHG_01818 9.8e-31 yrzR
NIPEHPHG_01819 1.8e-83 yrrD S protein conserved in bacteria
NIPEHPHG_01820 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NIPEHPHG_01821 1.4e-15 S COG0457 FOG TPR repeat
NIPEHPHG_01822 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NIPEHPHG_01823 4.7e-213 iscS 2.8.1.7 E Cysteine desulfurase
NIPEHPHG_01824 1.2e-70 cymR K Transcriptional regulator
NIPEHPHG_01825 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NIPEHPHG_01826 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NIPEHPHG_01827 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NIPEHPHG_01828 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
NIPEHPHG_01830 3.9e-263 lytH 3.5.1.28 M COG3103 SH3 domain protein
NIPEHPHG_01831 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NIPEHPHG_01832 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NIPEHPHG_01833 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NIPEHPHG_01834 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NIPEHPHG_01835 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
NIPEHPHG_01836 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
NIPEHPHG_01837 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NIPEHPHG_01838 9.4e-49 yrzD S Post-transcriptional regulator
NIPEHPHG_01839 5.7e-270 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NIPEHPHG_01840 2.2e-114 yrbG S membrane
NIPEHPHG_01841 1.2e-74 yrzE S Protein of unknown function (DUF3792)
NIPEHPHG_01842 1.1e-38 yajC U Preprotein translocase subunit YajC
NIPEHPHG_01843 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NIPEHPHG_01844 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NIPEHPHG_01845 2.6e-18 yrzS S Protein of unknown function (DUF2905)
NIPEHPHG_01846 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NIPEHPHG_01847 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NIPEHPHG_01848 4.8e-93 bofC S BofC C-terminal domain
NIPEHPHG_01849 5.3e-253 csbX EGP Major facilitator Superfamily
NIPEHPHG_01850 1.3e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
NIPEHPHG_01851 6.5e-119 yrzF T serine threonine protein kinase
NIPEHPHG_01853 2.6e-35 S Family of unknown function (DUF5412)
NIPEHPHG_01854 1.8e-262 alsT E Sodium alanine symporter
NIPEHPHG_01855 1.9e-127 yebC K transcriptional regulatory protein
NIPEHPHG_01856 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NIPEHPHG_01857 9.8e-158 safA M spore coat assembly protein SafA
NIPEHPHG_01858 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NIPEHPHG_01859 5.4e-161 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
NIPEHPHG_01860 2.7e-307 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
NIPEHPHG_01861 1.2e-230 nifS 2.8.1.7 E Cysteine desulfurase
NIPEHPHG_01862 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
NIPEHPHG_01863 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
NIPEHPHG_01864 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
NIPEHPHG_01865 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NIPEHPHG_01866 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
NIPEHPHG_01867 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NIPEHPHG_01868 4.1e-56 ysxB J ribosomal protein
NIPEHPHG_01869 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NIPEHPHG_01870 9.2e-161 spoIVFB S Stage IV sporulation protein
NIPEHPHG_01871 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
NIPEHPHG_01872 2.5e-144 minD D Belongs to the ParA family
NIPEHPHG_01873 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NIPEHPHG_01874 1.4e-84 mreD M shape-determining protein
NIPEHPHG_01875 2.8e-157 mreC M Involved in formation and maintenance of cell shape
NIPEHPHG_01876 1.8e-184 mreB D Rod shape-determining protein MreB
NIPEHPHG_01877 5.9e-126 radC E Belongs to the UPF0758 family
NIPEHPHG_01878 2.8e-102 maf D septum formation protein Maf
NIPEHPHG_01879 1.1e-168 spoIIB S Sporulation related domain
NIPEHPHG_01880 6.6e-85 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NIPEHPHG_01881 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NIPEHPHG_01882 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NIPEHPHG_01883 1.6e-25
NIPEHPHG_01884 1.6e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NIPEHPHG_01885 1.9e-226 spoVID M stage VI sporulation protein D
NIPEHPHG_01886 4.6e-249 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NIPEHPHG_01887 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
NIPEHPHG_01888 4.4e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NIPEHPHG_01889 3e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NIPEHPHG_01890 3.6e-146 hemX O cytochrome C
NIPEHPHG_01891 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NIPEHPHG_01892 1.4e-89 ysxD
NIPEHPHG_01893 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
NIPEHPHG_01894 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NIPEHPHG_01895 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
NIPEHPHG_01896 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NIPEHPHG_01897 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NIPEHPHG_01898 2.3e-187 ysoA H Tetratricopeptide repeat
NIPEHPHG_01899 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NIPEHPHG_01900 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NIPEHPHG_01901 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NIPEHPHG_01902 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NIPEHPHG_01903 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NIPEHPHG_01904 3.5e-83 ilvN 2.2.1.6 E Acetolactate synthase
NIPEHPHG_01905 0.0 ilvB 2.2.1.6 E Acetolactate synthase
NIPEHPHG_01907 7.6e-82 ysnE K acetyltransferase
NIPEHPHG_01908 9.1e-134 ysnF S protein conserved in bacteria
NIPEHPHG_01910 1.4e-92 ysnB S Phosphoesterase
NIPEHPHG_01911 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NIPEHPHG_01912 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NIPEHPHG_01913 2.9e-196 gerM S COG5401 Spore germination protein
NIPEHPHG_01914 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NIPEHPHG_01915 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
NIPEHPHG_01916 3.3e-30 gerE K Transcriptional regulator
NIPEHPHG_01917 1.6e-76 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
NIPEHPHG_01918 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NIPEHPHG_01919 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NIPEHPHG_01920 2.4e-107 sdhC C succinate dehydrogenase
NIPEHPHG_01921 1.2e-79 yslB S Protein of unknown function (DUF2507)
NIPEHPHG_01922 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NIPEHPHG_01923 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NIPEHPHG_01924 2e-52 trxA O Belongs to the thioredoxin family
NIPEHPHG_01925 5.7e-304 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
NIPEHPHG_01927 2.1e-177 etfA C Electron transfer flavoprotein
NIPEHPHG_01928 4.5e-135 etfB C Electron transfer flavoprotein
NIPEHPHG_01929 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NIPEHPHG_01930 2.7e-100 fadR K Transcriptional regulator
NIPEHPHG_01931 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NIPEHPHG_01932 7.3e-68 yshE S membrane
NIPEHPHG_01933 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NIPEHPHG_01934 0.0 polX L COG1796 DNA polymerase IV (family X)
NIPEHPHG_01935 1.3e-85 cvpA S membrane protein, required for colicin V production
NIPEHPHG_01936 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NIPEHPHG_01937 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NIPEHPHG_01938 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NIPEHPHG_01939 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NIPEHPHG_01940 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIPEHPHG_01941 2.6e-32 sspI S Belongs to the SspI family
NIPEHPHG_01942 4.4e-208 ysfB KT regulator
NIPEHPHG_01943 7.2e-264 glcD 1.1.3.15 C Glycolate oxidase subunit
NIPEHPHG_01944 5.6e-258 glcF C Glycolate oxidase
NIPEHPHG_01945 3.6e-38 ysfE 4.4.1.5 E lactoylglutathione lyase activity
NIPEHPHG_01947 0.0 cstA T Carbon starvation protein
NIPEHPHG_01948 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
NIPEHPHG_01949 3.4e-144 araQ G transport system permease
NIPEHPHG_01950 1.4e-167 araP G carbohydrate transport
NIPEHPHG_01951 2.8e-254 araN G carbohydrate transport
NIPEHPHG_01952 5e-226 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NIPEHPHG_01953 4.1e-147 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
NIPEHPHG_01954 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NIPEHPHG_01955 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
NIPEHPHG_01956 1.9e-294 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NIPEHPHG_01957 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NIPEHPHG_01958 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
NIPEHPHG_01959 9.2e-68 ysdB S Sigma-w pathway protein YsdB
NIPEHPHG_01960 7.5e-45 ysdA S Membrane
NIPEHPHG_01961 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NIPEHPHG_01962 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NIPEHPHG_01963 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NIPEHPHG_01965 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NIPEHPHG_01966 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NIPEHPHG_01967 6.3e-131 lytT T COG3279 Response regulator of the LytR AlgR family
NIPEHPHG_01968 0.0 lytS 2.7.13.3 T Histidine kinase
NIPEHPHG_01969 1.5e-149 ysaA S HAD-hyrolase-like
NIPEHPHG_01970 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NIPEHPHG_01971 3.8e-159 ytxC S YtxC-like family
NIPEHPHG_01972 4.9e-111 ytxB S SNARE associated Golgi protein
NIPEHPHG_01973 3e-173 dnaI L Primosomal protein DnaI
NIPEHPHG_01974 3.5e-266 dnaB L Membrane attachment protein
NIPEHPHG_01975 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NIPEHPHG_01976 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NIPEHPHG_01977 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NIPEHPHG_01978 9.9e-67 ytcD K Transcriptional regulator
NIPEHPHG_01979 4.9e-205 ytbD EGP Major facilitator Superfamily
NIPEHPHG_01980 8.9e-161 ytbE S reductase
NIPEHPHG_01981 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NIPEHPHG_01982 1.1e-107 ytaF P Probably functions as a manganese efflux pump
NIPEHPHG_01983 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NIPEHPHG_01984 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NIPEHPHG_01985 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
NIPEHPHG_01986 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NIPEHPHG_01987 1.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
NIPEHPHG_01988 1.8e-242 icd 1.1.1.42 C isocitrate
NIPEHPHG_01989 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
NIPEHPHG_01990 4.7e-71 yeaL S membrane
NIPEHPHG_01991 2.6e-192 ytvI S sporulation integral membrane protein YtvI
NIPEHPHG_01992 1.8e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
NIPEHPHG_01993 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NIPEHPHG_01994 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NIPEHPHG_01995 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NIPEHPHG_01996 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NIPEHPHG_01997 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
NIPEHPHG_01998 0.0 dnaE 2.7.7.7 L DNA polymerase
NIPEHPHG_01999 3.2e-56 ytrH S Sporulation protein YtrH
NIPEHPHG_02000 8.2e-69 ytrI
NIPEHPHG_02001 9.2e-29
NIPEHPHG_02002 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
NIPEHPHG_02003 2.4e-47 ytpI S YtpI-like protein
NIPEHPHG_02004 8e-241 ytoI K transcriptional regulator containing CBS domains
NIPEHPHG_02005 1.2e-158 ytnM S membrane transporter protein
NIPEHPHG_02006 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
NIPEHPHG_02007 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
NIPEHPHG_02008 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NIPEHPHG_02009 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
NIPEHPHG_02010 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NIPEHPHG_02011 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NIPEHPHG_02012 7.6e-121 tcyM U Binding-protein-dependent transport system inner membrane component
NIPEHPHG_02013 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
NIPEHPHG_02014 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
NIPEHPHG_02015 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
NIPEHPHG_02016 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
NIPEHPHG_02017 2.9e-173 ytlI K LysR substrate binding domain
NIPEHPHG_02018 1.7e-130 ytkL S Belongs to the UPF0173 family
NIPEHPHG_02019 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NIPEHPHG_02021 3.1e-267 argH 4.3.2.1 E argininosuccinate lyase
NIPEHPHG_02022 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NIPEHPHG_02023 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
NIPEHPHG_02024 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NIPEHPHG_02025 7e-165 ytxK 2.1.1.72 L DNA methylase
NIPEHPHG_02026 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NIPEHPHG_02027 8.7e-70 ytfJ S Sporulation protein YtfJ
NIPEHPHG_02028 5.6e-116 ytfI S Protein of unknown function (DUF2953)
NIPEHPHG_02029 1.3e-87 yteJ S RDD family
NIPEHPHG_02030 2.4e-181 sppA OU signal peptide peptidase SppA
NIPEHPHG_02031 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NIPEHPHG_02032 0.0 ytcJ S amidohydrolase
NIPEHPHG_02033 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NIPEHPHG_02034 2e-29 sspB S spore protein
NIPEHPHG_02035 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NIPEHPHG_02036 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
NIPEHPHG_02037 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
NIPEHPHG_02038 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NIPEHPHG_02039 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NIPEHPHG_02040 3.4e-109 yttP K Transcriptional regulator
NIPEHPHG_02041 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
NIPEHPHG_02042 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
NIPEHPHG_02043 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NIPEHPHG_02045 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NIPEHPHG_02046 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NIPEHPHG_02047 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NIPEHPHG_02048 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
NIPEHPHG_02049 1.9e-225 acuC BQ histone deacetylase
NIPEHPHG_02050 1.4e-125 motS N Flagellar motor protein
NIPEHPHG_02051 7.1e-147 motA N flagellar motor
NIPEHPHG_02052 1.7e-182 ccpA K catabolite control protein A
NIPEHPHG_02053 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NIPEHPHG_02054 4.4e-55 ytxJ O Protein of unknown function (DUF2847)
NIPEHPHG_02055 6.6e-17 ytxH S COG4980 Gas vesicle protein
NIPEHPHG_02056 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NIPEHPHG_02057 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NIPEHPHG_02058 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
NIPEHPHG_02059 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NIPEHPHG_02060 9.8e-149 ytpQ S Belongs to the UPF0354 family
NIPEHPHG_02061 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NIPEHPHG_02062 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
NIPEHPHG_02063 4.7e-207 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
NIPEHPHG_02064 9.8e-52 ytzB S small secreted protein
NIPEHPHG_02065 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
NIPEHPHG_02066 6.4e-151 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
NIPEHPHG_02067 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NIPEHPHG_02068 2e-45 ytzH S YtzH-like protein
NIPEHPHG_02069 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
NIPEHPHG_02070 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
NIPEHPHG_02071 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NIPEHPHG_02072 1.3e-165 ytlQ
NIPEHPHG_02073 4.3e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NIPEHPHG_02074 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NIPEHPHG_02075 7.1e-272 pepV 3.5.1.18 E Dipeptidase
NIPEHPHG_02076 7.2e-226 pbuO S permease
NIPEHPHG_02077 3.9e-207 ythQ U Bacterial ABC transporter protein EcsB
NIPEHPHG_02078 4.3e-132 ythP V ABC transporter
NIPEHPHG_02079 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
NIPEHPHG_02080 2.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NIPEHPHG_02081 1.9e-281 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NIPEHPHG_02082 8.2e-232 ytfP S HI0933-like protein
NIPEHPHG_02083 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
NIPEHPHG_02084 3.1e-26 yteV S Sporulation protein Cse60
NIPEHPHG_02085 4.8e-117 yteU S Integral membrane protein
NIPEHPHG_02086 9.2e-258 yteT S Oxidoreductase family, C-terminal alpha/beta domain
NIPEHPHG_02087 4.6e-73 yteS G transport
NIPEHPHG_02088 4.7e-226 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
NIPEHPHG_02089 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NIPEHPHG_02090 0.0 ytdP K Transcriptional regulator
NIPEHPHG_02091 1.2e-290 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
NIPEHPHG_02092 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
NIPEHPHG_02093 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
NIPEHPHG_02094 1.9e-225 bioI 1.14.14.46 C Cytochrome P450
NIPEHPHG_02095 2.2e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NIPEHPHG_02096 3.7e-128 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NIPEHPHG_02097 1.4e-220 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NIPEHPHG_02098 2.4e-261 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NIPEHPHG_02099 1.6e-142 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NIPEHPHG_02100 1.3e-173 ytaP S Acetyl xylan esterase (AXE1)
NIPEHPHG_02101 2.3e-190 msmR K Transcriptional regulator
NIPEHPHG_02102 2.3e-248 msmE G Bacterial extracellular solute-binding protein
NIPEHPHG_02103 3.7e-168 amyD P ABC transporter
NIPEHPHG_02104 4.4e-144 amyC P ABC transporter (permease)
NIPEHPHG_02105 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NIPEHPHG_02106 2.1e-51 ytwF P Sulfurtransferase
NIPEHPHG_02107 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NIPEHPHG_02108 7.7e-55 ytvB S Protein of unknown function (DUF4257)
NIPEHPHG_02109 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NIPEHPHG_02110 2.1e-211 yttB EGP Major facilitator Superfamily
NIPEHPHG_02111 1.8e-43 yttA 2.7.13.3 S Pfam Transposase IS66
NIPEHPHG_02112 0.0 bceB V ABC transporter (permease)
NIPEHPHG_02113 1.1e-138 bceA V ABC transporter, ATP-binding protein
NIPEHPHG_02114 5.6e-186 T PhoQ Sensor
NIPEHPHG_02115 5.2e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NIPEHPHG_02116 8.5e-235 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
NIPEHPHG_02117 3.1e-127 ytrE V ABC transporter, ATP-binding protein
NIPEHPHG_02118 5.9e-148
NIPEHPHG_02119 6.1e-169 P ABC-2 family transporter protein
NIPEHPHG_02120 1.1e-161 ytrB P abc transporter atp-binding protein
NIPEHPHG_02121 5.1e-66 ytrA K GntR family transcriptional regulator
NIPEHPHG_02123 6.7e-41 ytzC S Protein of unknown function (DUF2524)
NIPEHPHG_02124 2.1e-190 yhcC S Fe-S oxidoreductase
NIPEHPHG_02125 3.3e-106 ytqB J Putative rRNA methylase
NIPEHPHG_02126 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
NIPEHPHG_02127 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
NIPEHPHG_02128 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NIPEHPHG_02129 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
NIPEHPHG_02130 0.0 asnB 6.3.5.4 E Asparagine synthase
NIPEHPHG_02131 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NIPEHPHG_02132 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NIPEHPHG_02133 1.2e-38 ytmB S Protein of unknown function (DUF2584)
NIPEHPHG_02134 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NIPEHPHG_02135 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NIPEHPHG_02136 1.4e-144 ytlC P ABC transporter
NIPEHPHG_02137 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NIPEHPHG_02138 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
NIPEHPHG_02139 5.4e-63 ytkC S Bacteriophage holin family
NIPEHPHG_02140 2.1e-76 dps P Belongs to the Dps family
NIPEHPHG_02142 3.6e-73 ytkA S YtkA-like
NIPEHPHG_02143 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NIPEHPHG_02144 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NIPEHPHG_02145 3.6e-41 rpmE2 J Ribosomal protein L31
NIPEHPHG_02146 4.7e-249 cydA 1.10.3.14 C oxidase, subunit
NIPEHPHG_02147 7.3e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NIPEHPHG_02148 1.1e-24 S Domain of Unknown Function (DUF1540)
NIPEHPHG_02149 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
NIPEHPHG_02150 3.2e-234 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NIPEHPHG_02151 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NIPEHPHG_02152 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
NIPEHPHG_02153 1.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NIPEHPHG_02154 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NIPEHPHG_02155 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NIPEHPHG_02156 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NIPEHPHG_02157 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NIPEHPHG_02158 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
NIPEHPHG_02159 2.6e-132 dksA T COG1734 DnaK suppressor protein
NIPEHPHG_02160 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
NIPEHPHG_02161 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NIPEHPHG_02162 3.9e-181 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
NIPEHPHG_02163 3.6e-235 ytcC M Glycosyltransferase Family 4
NIPEHPHG_02165 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
NIPEHPHG_02166 1.8e-217 cotSA M Glycosyl transferases group 1
NIPEHPHG_02167 1.8e-206 cotI S Spore coat protein
NIPEHPHG_02168 9.9e-77 tspO T membrane
NIPEHPHG_02169 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NIPEHPHG_02170 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
NIPEHPHG_02171 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
NIPEHPHG_02172 3.6e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NIPEHPHG_02173 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NIPEHPHG_02182 7.8e-08
NIPEHPHG_02183 1.3e-09
NIPEHPHG_02190 2e-08
NIPEHPHG_02195 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
NIPEHPHG_02196 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
NIPEHPHG_02197 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NIPEHPHG_02198 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
NIPEHPHG_02199 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
NIPEHPHG_02201 0.0 htpG O Molecular chaperone. Has ATPase activity
NIPEHPHG_02202 2.3e-246 csbC EGP Major facilitator Superfamily
NIPEHPHG_02203 8.3e-48 yxcD S Protein of unknown function (DUF2653)
NIPEHPHG_02205 3.7e-176 iolS C Aldo keto reductase
NIPEHPHG_02206 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
NIPEHPHG_02207 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NIPEHPHG_02208 1.1e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NIPEHPHG_02209 2.9e-179 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NIPEHPHG_02210 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NIPEHPHG_02211 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NIPEHPHG_02212 1.3e-235 iolF EGP Major facilitator Superfamily
NIPEHPHG_02213 1.4e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NIPEHPHG_02214 8.6e-167 iolH G Xylose isomerase-like TIM barrel
NIPEHPHG_02215 1.2e-138 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NIPEHPHG_02216 5.4e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NIPEHPHG_02217 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NIPEHPHG_02218 1.3e-182 T PhoQ Sensor
NIPEHPHG_02219 9.4e-141 yxdL V ABC transporter, ATP-binding protein
NIPEHPHG_02220 0.0 yxdM V ABC transporter (permease)
NIPEHPHG_02221 1.5e-58 yxeA S Protein of unknown function (DUF1093)
NIPEHPHG_02222 6e-177 fhuD P ABC transporter
NIPEHPHG_02223 8.5e-69
NIPEHPHG_02224 1.9e-16 yxeD
NIPEHPHG_02225 1.3e-20 yxeE
NIPEHPHG_02228 6.2e-151 yidA S hydrolases of the HAD superfamily
NIPEHPHG_02229 1.4e-60 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
NIPEHPHG_02230 1.8e-68 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
NIPEHPHG_02232 2.2e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NIPEHPHG_02233 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NIPEHPHG_02234 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
NIPEHPHG_02235 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
NIPEHPHG_02236 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
NIPEHPHG_02237 3.8e-215 yxeP 3.5.1.47 E hydrolase activity
NIPEHPHG_02238 2e-255 yxeQ S MmgE/PrpD family
NIPEHPHG_02239 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
NIPEHPHG_02240 1e-95 yxxB S Domain of Unknown Function (DUF1206)
NIPEHPHG_02241 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NIPEHPHG_02242 7e-116 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NIPEHPHG_02243 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NIPEHPHG_02244 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
NIPEHPHG_02245 3.4e-250 lysP E amino acid
NIPEHPHG_02246 6.8e-181 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NIPEHPHG_02247 4.7e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
NIPEHPHG_02248 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NIPEHPHG_02249 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
NIPEHPHG_02250 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
NIPEHPHG_02251 6.3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NIPEHPHG_02252 2.1e-21 S Domain of unknown function (DUF5082)
NIPEHPHG_02253 3.6e-39 yxiC S Family of unknown function (DUF5344)
NIPEHPHG_02254 0.0 S nuclease activity
NIPEHPHG_02255 2.2e-78 S SMI1 / KNR4 family
NIPEHPHG_02256 3.6e-51
NIPEHPHG_02257 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NIPEHPHG_02258 1.1e-280 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NIPEHPHG_02259 1.1e-72 yxiE T Belongs to the universal stress protein A family
NIPEHPHG_02260 2.9e-168 yxxF EG EamA-like transporter family
NIPEHPHG_02261 0.0 wapA M COG3209 Rhs family protein
NIPEHPHG_02262 1.5e-71 yxxG
NIPEHPHG_02263 1.7e-84
NIPEHPHG_02264 6.4e-63
NIPEHPHG_02265 3.7e-75 yxiG
NIPEHPHG_02266 4.9e-46
NIPEHPHG_02267 3.8e-81
NIPEHPHG_02268 1.2e-96 yxiI S Protein of unknown function (DUF2716)
NIPEHPHG_02269 1.6e-48 yxiJ S YxiJ-like protein
NIPEHPHG_02272 7.5e-219 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
NIPEHPHG_02273 1e-265 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NIPEHPHG_02274 3e-232 yxiO S COG2270 Permeases of the major facilitator superfamily
NIPEHPHG_02275 6.6e-114
NIPEHPHG_02276 8.3e-151 licT K transcriptional antiterminator
NIPEHPHG_02277 5e-144 exoK GH16 M licheninase activity
NIPEHPHG_02278 6.6e-224 citH C Citrate transporter
NIPEHPHG_02279 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
NIPEHPHG_02280 2.7e-48 yxiS
NIPEHPHG_02281 1.2e-22 T Domain of unknown function (DUF4163)
NIPEHPHG_02282 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NIPEHPHG_02283 2.2e-145 rlmA 2.1.1.187 Q Methyltransferase domain
NIPEHPHG_02284 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
NIPEHPHG_02285 1.4e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NIPEHPHG_02286 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NIPEHPHG_02287 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NIPEHPHG_02288 1e-220 yxjG 2.1.1.14 E Methionine synthase
NIPEHPHG_02289 5.5e-222 yxjG 2.1.1.14 E Methionine synthase
NIPEHPHG_02290 1e-87 yxjI S LURP-one-related
NIPEHPHG_02293 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NIPEHPHG_02294 8.9e-116 K helix_turn_helix, Lux Regulon
NIPEHPHG_02295 1.5e-193 yxjM T Signal transduction histidine kinase
NIPEHPHG_02296 2.4e-78 S Protein of unknown function (DUF1453)
NIPEHPHG_02297 1.9e-166 yxjO K LysR substrate binding domain
NIPEHPHG_02298 1.3e-95 yxkA S Phosphatidylethanolamine-binding protein
NIPEHPHG_02299 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NIPEHPHG_02300 4.1e-73 yxkC S Domain of unknown function (DUF4352)
NIPEHPHG_02301 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NIPEHPHG_02302 2.5e-275 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NIPEHPHG_02303 4.8e-165 lrp QT PucR C-terminal helix-turn-helix domain
NIPEHPHG_02304 5.9e-205 msmK P Belongs to the ABC transporter superfamily
NIPEHPHG_02305 3e-156 yxkH G Polysaccharide deacetylase
NIPEHPHG_02307 0.0 3.4.24.84 O Peptidase family M48
NIPEHPHG_02308 1.5e-229 cimH C COG3493 Na citrate symporter
NIPEHPHG_02309 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
NIPEHPHG_02310 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
NIPEHPHG_02311 0.0 cydD V ATP-binding
NIPEHPHG_02312 0.0 cydD V ATP-binding protein
NIPEHPHG_02313 8e-162 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NIPEHPHG_02314 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
NIPEHPHG_02315 4.7e-91 sigY K Belongs to the sigma-70 factor family. ECF subfamily
NIPEHPHG_02316 3.9e-48 yxlC S Family of unknown function (DUF5345)
NIPEHPHG_02317 1.2e-31
NIPEHPHG_02318 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
NIPEHPHG_02319 5.1e-167 yxlF V ABC transporter, ATP-binding protein
NIPEHPHG_02320 1.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NIPEHPHG_02321 5.3e-215 yxlH EGP Major facilitator Superfamily
NIPEHPHG_02322 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NIPEHPHG_02323 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NIPEHPHG_02324 1.1e-19 yxzF
NIPEHPHG_02325 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
NIPEHPHG_02326 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
NIPEHPHG_02327 7.4e-250 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIPEHPHG_02328 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
NIPEHPHG_02329 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NIPEHPHG_02330 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NIPEHPHG_02331 6.6e-139 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
NIPEHPHG_02332 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NIPEHPHG_02333 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIPEHPHG_02334 1.2e-232 dltB M membrane protein involved in D-alanine export
NIPEHPHG_02335 7.9e-293 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIPEHPHG_02336 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
NIPEHPHG_02337 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
NIPEHPHG_02338 1.4e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
NIPEHPHG_02339 4.4e-233 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NIPEHPHG_02340 8.1e-88 ywaE K Transcriptional regulator
NIPEHPHG_02341 1.7e-128 ywaF S Integral membrane protein
NIPEHPHG_02342 7e-169 gspA M General stress
NIPEHPHG_02343 4e-153 sacY K transcriptional antiterminator
NIPEHPHG_02344 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NIPEHPHG_02345 1.6e-277 epr 3.4.21.62 O Belongs to the peptidase S8 family
NIPEHPHG_02346 5.8e-247 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIPEHPHG_02347 1.8e-127 ywbB S Protein of unknown function (DUF2711)
NIPEHPHG_02348 4.4e-67 ywbC 4.4.1.5 E glyoxalase
NIPEHPHG_02349 8.9e-223 ywbD 2.1.1.191 J Methyltransferase
NIPEHPHG_02350 1.2e-28 ywbE S Uncharacterized conserved protein (DUF2196)
NIPEHPHG_02351 1.9e-209 ywbF EGP Major facilitator Superfamily
NIPEHPHG_02352 2.3e-111 ywbG M effector of murein hydrolase
NIPEHPHG_02353 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NIPEHPHG_02354 4.3e-153 ywbI K Transcriptional regulator
NIPEHPHG_02355 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NIPEHPHG_02356 4.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NIPEHPHG_02357 8.2e-255 P COG0672 High-affinity Fe2 Pb2 permease
NIPEHPHG_02358 2e-187 ycdO P periplasmic lipoprotein involved in iron transport
NIPEHPHG_02359 2.6e-225 ywbN P Dyp-type peroxidase family protein
NIPEHPHG_02360 1.9e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NIPEHPHG_02361 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NIPEHPHG_02362 9.8e-49 ywcB S Protein of unknown function, DUF485
NIPEHPHG_02364 2.2e-122 ywcC K transcriptional regulator
NIPEHPHG_02365 9.5e-60 gtcA S GtrA-like protein
NIPEHPHG_02366 6.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NIPEHPHG_02367 3.7e-306 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NIPEHPHG_02368 1e-35 ywzA S membrane
NIPEHPHG_02369 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NIPEHPHG_02370 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NIPEHPHG_02371 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NIPEHPHG_02372 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NIPEHPHG_02373 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
NIPEHPHG_02374 2.9e-202 rodA D Belongs to the SEDS family
NIPEHPHG_02375 7.2e-138 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
NIPEHPHG_02376 5.1e-187 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NIPEHPHG_02377 0.0 vpr O Belongs to the peptidase S8 family
NIPEHPHG_02379 2.4e-150 sacT K transcriptional antiterminator
NIPEHPHG_02380 1e-139 focA P Formate/nitrite transporter
NIPEHPHG_02381 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NIPEHPHG_02382 9.5e-296 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
NIPEHPHG_02383 2e-28 ywdA
NIPEHPHG_02384 9.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NIPEHPHG_02385 1.3e-57 pex K Transcriptional regulator PadR-like family
NIPEHPHG_02386 1.4e-113 ywdD
NIPEHPHG_02388 1.1e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
NIPEHPHG_02389 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NIPEHPHG_02390 5.9e-263 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NIPEHPHG_02391 7.7e-49 ywdI S Family of unknown function (DUF5327)
NIPEHPHG_02392 1.3e-238 ywdJ F Xanthine uracil
NIPEHPHG_02393 4.3e-59 ywdK S small membrane protein
NIPEHPHG_02394 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NIPEHPHG_02395 2.8e-145 spsA M Spore Coat
NIPEHPHG_02396 1.5e-269 spsB M Capsule polysaccharide biosynthesis protein
NIPEHPHG_02397 1.6e-224 spsC E Belongs to the DegT DnrJ EryC1 family
NIPEHPHG_02398 4e-164 spsD 2.3.1.210 K Spore Coat
NIPEHPHG_02399 3.2e-214 spsE 2.5.1.56 M acid synthase
NIPEHPHG_02400 9.7e-132 spsF M Spore Coat
NIPEHPHG_02401 1.7e-190 spsG M Spore Coat
NIPEHPHG_02402 1.9e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NIPEHPHG_02403 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NIPEHPHG_02404 5.3e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NIPEHPHG_02405 3.5e-87 spsL 5.1.3.13 M Spore Coat
NIPEHPHG_02406 1.8e-78
NIPEHPHG_02407 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NIPEHPHG_02408 1.4e-297 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NIPEHPHG_02409 0.0 rocB E arginine degradation protein
NIPEHPHG_02410 4e-262 lysP E amino acid
NIPEHPHG_02411 4.6e-206 ywfA EGP Major facilitator Superfamily
NIPEHPHG_02412 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NIPEHPHG_02413 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NIPEHPHG_02414 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NIPEHPHG_02415 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NIPEHPHG_02416 2.9e-210 bacE EGP Major facilitator Superfamily
NIPEHPHG_02417 2.7e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
NIPEHPHG_02418 4e-139 IQ Enoyl-(Acyl carrier protein) reductase
NIPEHPHG_02419 1.1e-146 ywfI C May function as heme-dependent peroxidase
NIPEHPHG_02420 6.6e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
NIPEHPHG_02421 9.2e-164 cysL K Transcriptional regulator
NIPEHPHG_02422 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NIPEHPHG_02423 5.2e-159 ywfM EG EamA-like transporter family
NIPEHPHG_02424 1.6e-111 rsfA_1
NIPEHPHG_02425 3.1e-36 ywzC S Belongs to the UPF0741 family
NIPEHPHG_02426 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
NIPEHPHG_02427 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
NIPEHPHG_02428 2.8e-79 yffB K Transcriptional regulator
NIPEHPHG_02429 2.2e-241 mmr U Major Facilitator Superfamily
NIPEHPHG_02431 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NIPEHPHG_02432 3.3e-71 ywhA K Transcriptional regulator
NIPEHPHG_02433 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
NIPEHPHG_02434 5.1e-119 ywhC S Peptidase family M50
NIPEHPHG_02435 5.2e-95 ywhD S YwhD family
NIPEHPHG_02436 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NIPEHPHG_02437 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NIPEHPHG_02438 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
NIPEHPHG_02439 1e-84 ywhH S Aminoacyl-tRNA editing domain
NIPEHPHG_02441 2.3e-79 S aspartate phosphatase
NIPEHPHG_02442 2.5e-205 ywhK CO amine dehydrogenase activity
NIPEHPHG_02443 2.9e-249 ywhL CO amine dehydrogenase activity
NIPEHPHG_02445 1.2e-249 L Peptidase, M16
NIPEHPHG_02446 2.7e-219 2.7.1.26, 2.7.7.2 L Peptidase, M16
NIPEHPHG_02447 3.1e-237 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
NIPEHPHG_02448 3.3e-132 cbiO V ABC transporter
NIPEHPHG_02450 2.6e-271 C Fe-S oxidoreductases
NIPEHPHG_02451 1e-07 S Bacteriocin subtilosin A
NIPEHPHG_02452 4.7e-73 ywiB S protein conserved in bacteria
NIPEHPHG_02453 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NIPEHPHG_02454 9.8e-214 narK P COG2223 Nitrate nitrite transporter
NIPEHPHG_02455 5.3e-130 fnr K helix_turn_helix, cAMP Regulatory protein
NIPEHPHG_02456 1.7e-139 ywiC S YwiC-like protein
NIPEHPHG_02457 7e-86 arfM T cyclic nucleotide binding
NIPEHPHG_02458 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NIPEHPHG_02459 1.9e-296 narH 1.7.5.1 C Nitrate reductase, beta
NIPEHPHG_02460 3.1e-93 narJ 1.7.5.1 C nitrate reductase
NIPEHPHG_02461 1.8e-124 narI 1.7.5.1 C nitrate reductase, gamma
NIPEHPHG_02462 6.4e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NIPEHPHG_02463 0.0 ywjA V ABC transporter
NIPEHPHG_02464 4.8e-96 ywjB H RibD C-terminal domain
NIPEHPHG_02465 2.7e-42 ywjC
NIPEHPHG_02466 6.6e-184 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NIPEHPHG_02467 2.3e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NIPEHPHG_02468 0.0 fadF C COG0247 Fe-S oxidoreductase
NIPEHPHG_02469 2.6e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
NIPEHPHG_02470 1.5e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NIPEHPHG_02471 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NIPEHPHG_02472 2.4e-92 ywjG S Domain of unknown function (DUF2529)
NIPEHPHG_02473 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
NIPEHPHG_02474 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
NIPEHPHG_02475 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NIPEHPHG_02476 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NIPEHPHG_02477 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
NIPEHPHG_02478 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NIPEHPHG_02479 1.1e-32 rpmE J Binds the 23S rRNA
NIPEHPHG_02480 2.4e-104 tdk 2.7.1.21 F thymidine kinase
NIPEHPHG_02481 0.0 sfcA 1.1.1.38 C malic enzyme
NIPEHPHG_02482 8.6e-160 ywkB S Membrane transport protein
NIPEHPHG_02483 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NIPEHPHG_02484 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NIPEHPHG_02485 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NIPEHPHG_02486 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NIPEHPHG_02488 3.4e-56 ywlA S Uncharacterised protein family (UPF0715)
NIPEHPHG_02489 6.1e-112 spoIIR S stage II sporulation protein R
NIPEHPHG_02490 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
NIPEHPHG_02491 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NIPEHPHG_02492 1.7e-91 mntP P Probably functions as a manganese efflux pump
NIPEHPHG_02493 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NIPEHPHG_02494 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
NIPEHPHG_02495 7.2e-95 ywlG S Belongs to the UPF0340 family
NIPEHPHG_02496 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NIPEHPHG_02497 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NIPEHPHG_02498 2.5e-62 atpI S ATP synthase
NIPEHPHG_02499 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
NIPEHPHG_02500 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NIPEHPHG_02501 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NIPEHPHG_02502 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NIPEHPHG_02503 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NIPEHPHG_02504 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NIPEHPHG_02505 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NIPEHPHG_02506 5.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NIPEHPHG_02507 4.3e-88 ywmA
NIPEHPHG_02508 1.3e-32 ywzB S membrane
NIPEHPHG_02509 1.6e-134 ywmB S TATA-box binding
NIPEHPHG_02510 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NIPEHPHG_02511 2e-178 spoIID D Stage II sporulation protein D
NIPEHPHG_02512 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
NIPEHPHG_02513 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
NIPEHPHG_02515 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NIPEHPHG_02516 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NIPEHPHG_02517 1.3e-103 S response regulator aspartate phosphatase
NIPEHPHG_02518 3e-84 ywmF S Peptidase M50
NIPEHPHG_02519 3.8e-11 csbD K CsbD-like
NIPEHPHG_02521 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NIPEHPHG_02522 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NIPEHPHG_02523 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NIPEHPHG_02524 1.7e-64 ywnA K Transcriptional regulator
NIPEHPHG_02525 1.6e-114 ywnB S NAD(P)H-binding
NIPEHPHG_02526 2.6e-59 ywnC S Family of unknown function (DUF5362)
NIPEHPHG_02527 4.1e-144 mta K transcriptional
NIPEHPHG_02528 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NIPEHPHG_02529 2.2e-70 ywnF S Family of unknown function (DUF5392)
NIPEHPHG_02530 2.7e-14 ywnC S Family of unknown function (DUF5362)
NIPEHPHG_02531 6.4e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
NIPEHPHG_02532 5.5e-126 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
NIPEHPHG_02533 3.5e-73 ywnJ S VanZ like family
NIPEHPHG_02534 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
NIPEHPHG_02535 1.6e-58 nrgB K Belongs to the P(II) protein family
NIPEHPHG_02536 2.5e-225 amt P Ammonium transporter
NIPEHPHG_02537 2.2e-76
NIPEHPHG_02538 4e-104 phzA Q Isochorismatase family
NIPEHPHG_02539 4.4e-242 ywoD EGP Major facilitator superfamily
NIPEHPHG_02540 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
NIPEHPHG_02541 1.2e-231 ywoF P Right handed beta helix region
NIPEHPHG_02542 2.7e-211 ywoG EGP Major facilitator Superfamily
NIPEHPHG_02543 2.1e-70 ywoH K COG1846 Transcriptional regulators
NIPEHPHG_02544 3e-44 spoIIID K Stage III sporulation protein D
NIPEHPHG_02545 3.5e-180 mbl D Rod shape-determining protein
NIPEHPHG_02546 6.9e-126 flhO N flagellar basal body
NIPEHPHG_02547 1.5e-141 flhP N flagellar basal body
NIPEHPHG_02548 2.1e-199 S aspartate phosphatase
NIPEHPHG_02549 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NIPEHPHG_02550 1.5e-54 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NIPEHPHG_02551 1.9e-153 ywpD T Histidine kinase
NIPEHPHG_02552 8e-51 srtA 3.4.22.70 M Sortase family
NIPEHPHG_02553 1.1e-66 ywpF S YwpF-like protein
NIPEHPHG_02554 1.3e-66 ywpG
NIPEHPHG_02555 9.8e-58 ssbB L Single-stranded DNA-binding protein
NIPEHPHG_02556 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
NIPEHPHG_02557 3.6e-157 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
NIPEHPHG_02558 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NIPEHPHG_02559 3.8e-309 ywqB S SWIM zinc finger
NIPEHPHG_02560 1.2e-17
NIPEHPHG_02561 2e-116 ywqC M biosynthesis protein
NIPEHPHG_02562 1.1e-119 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
NIPEHPHG_02563 1.4e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
NIPEHPHG_02564 3e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NIPEHPHG_02565 3.4e-154 ywqG S Domain of unknown function (DUF1963)
NIPEHPHG_02566 3.3e-15 S Domain of unknown function (DUF5082)
NIPEHPHG_02567 1.3e-38 ywqI S Family of unknown function (DUF5344)
NIPEHPHG_02568 0.0 ywqJ L nucleic acid phosphodiester bond hydrolysis
NIPEHPHG_02569 1.7e-52 S MORN repeat variant
NIPEHPHG_02570 4.5e-137 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NIPEHPHG_02571 2.9e-162 K Transcriptional regulator
NIPEHPHG_02572 2.7e-102 ywqN S NAD(P)H-dependent
NIPEHPHG_02574 6.9e-90 ywrA P COG2059 Chromate transport protein ChrA
NIPEHPHG_02575 2.4e-104 ywrB P Chromate transporter
NIPEHPHG_02576 2.1e-82 ywrC K Transcriptional regulator
NIPEHPHG_02577 9.6e-310 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NIPEHPHG_02578 2.9e-54 S Domain of unknown function (DUF4181)
NIPEHPHG_02579 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NIPEHPHG_02580 3.7e-12
NIPEHPHG_02581 1.2e-210 cotH M Spore Coat
NIPEHPHG_02582 7.6e-131 cotB
NIPEHPHG_02583 7.5e-126 ywrJ
NIPEHPHG_02584 1.9e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NIPEHPHG_02585 1.1e-169 alsR K LysR substrate binding domain
NIPEHPHG_02586 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NIPEHPHG_02587 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
NIPEHPHG_02588 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
NIPEHPHG_02589 3.6e-48 ywsA S Protein of unknown function (DUF3892)
NIPEHPHG_02590 4.6e-94 batE T Sh3 type 3 domain protein
NIPEHPHG_02591 4.4e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
NIPEHPHG_02592 1.4e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
NIPEHPHG_02593 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NIPEHPHG_02594 2.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NIPEHPHG_02595 2.9e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NIPEHPHG_02596 1.9e-178 rbsR K transcriptional
NIPEHPHG_02597 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
NIPEHPHG_02598 8.6e-70 pgsC S biosynthesis protein
NIPEHPHG_02599 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NIPEHPHG_02600 3.6e-21 ywtC
NIPEHPHG_02601 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NIPEHPHG_02602 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
NIPEHPHG_02603 8.4e-171 ywtF K Transcriptional regulator
NIPEHPHG_02604 1.9e-248 ywtG EGP Major facilitator Superfamily
NIPEHPHG_02605 7.6e-216 gerAC S Spore germination protein
NIPEHPHG_02606 7.5e-200 gerBB E Spore germination protein
NIPEHPHG_02607 3.5e-266 gerBA EG Spore germination protein
NIPEHPHG_02608 7.1e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
NIPEHPHG_02609 7.2e-217 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NIPEHPHG_02610 1.2e-260
NIPEHPHG_02611 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NIPEHPHG_02612 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NIPEHPHG_02613 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
NIPEHPHG_02614 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
NIPEHPHG_02615 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NIPEHPHG_02616 1.1e-150 tagG GM Transport permease protein
NIPEHPHG_02617 5.2e-279 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NIPEHPHG_02618 1.6e-100 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NIPEHPHG_02620 8.1e-257 ggaA M Glycosyltransferase like family 2
NIPEHPHG_02621 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NIPEHPHG_02622 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NIPEHPHG_02623 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NIPEHPHG_02624 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NIPEHPHG_02625 6e-38
NIPEHPHG_02626 0.0 lytB 3.5.1.28 D Stage II sporulation protein
NIPEHPHG_02627 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NIPEHPHG_02628 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NIPEHPHG_02629 3.3e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NIPEHPHG_02630 7.4e-222 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
NIPEHPHG_02631 2.4e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NIPEHPHG_02632 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
NIPEHPHG_02633 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
NIPEHPHG_02634 3.1e-144 tuaG GT2 M Glycosyltransferase like family 2
NIPEHPHG_02635 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
NIPEHPHG_02636 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NIPEHPHG_02637 6e-163 yvhJ K Transcriptional regulator
NIPEHPHG_02638 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
NIPEHPHG_02639 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NIPEHPHG_02640 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NIPEHPHG_02641 7.3e-155 degV S protein conserved in bacteria
NIPEHPHG_02642 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NIPEHPHG_02643 5.7e-46 comFB S Late competence development protein ComFB
NIPEHPHG_02644 2.7e-129 comFC S Phosphoribosyl transferase domain
NIPEHPHG_02645 7e-74 yvyF S flagellar protein
NIPEHPHG_02646 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
NIPEHPHG_02647 2.4e-78 flgN NOU FlgN protein
NIPEHPHG_02648 1.2e-264 flgK N flagellar hook-associated protein
NIPEHPHG_02649 1.1e-156 flgL N Belongs to the bacterial flagellin family
NIPEHPHG_02650 2.6e-50 yviE
NIPEHPHG_02651 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NIPEHPHG_02652 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NIPEHPHG_02653 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NIPEHPHG_02654 6.1e-57 flaG N flagellar protein FlaG
NIPEHPHG_02655 1.3e-266 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NIPEHPHG_02656 2.9e-69 fliS N flagellar protein FliS
NIPEHPHG_02657 1.9e-08 fliT S bacterial-type flagellum organization
NIPEHPHG_02658 2.8e-66
NIPEHPHG_02659 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NIPEHPHG_02660 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NIPEHPHG_02661 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NIPEHPHG_02662 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
NIPEHPHG_02663 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
NIPEHPHG_02664 1.6e-123 ftsE D cell division ATP-binding protein FtsE
NIPEHPHG_02665 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NIPEHPHG_02666 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
NIPEHPHG_02667 5.3e-56 swrA S Swarming motility protein
NIPEHPHG_02668 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NIPEHPHG_02669 7.9e-228 yvkA EGP Major facilitator Superfamily
NIPEHPHG_02670 7e-101 yvkB K Transcriptional regulator
NIPEHPHG_02671 0.0 yvkC 2.7.9.2 GT Phosphotransferase
NIPEHPHG_02672 1.2e-30 csbA S protein conserved in bacteria
NIPEHPHG_02673 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NIPEHPHG_02674 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NIPEHPHG_02675 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NIPEHPHG_02676 6.7e-34 yvkN
NIPEHPHG_02677 8e-49 yvlA
NIPEHPHG_02678 3.4e-168 yvlB S Putative adhesin
NIPEHPHG_02679 2.6e-26 pspB KT PspC domain
NIPEHPHG_02680 1.2e-50 yvlD S Membrane
NIPEHPHG_02681 2.7e-203 yvmA EGP Major facilitator Superfamily
NIPEHPHG_02682 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
NIPEHPHG_02683 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
NIPEHPHG_02684 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
NIPEHPHG_02685 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
NIPEHPHG_02686 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
NIPEHPHG_02687 3.6e-134 yvoA K transcriptional
NIPEHPHG_02688 8.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NIPEHPHG_02689 6.8e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NIPEHPHG_02690 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NIPEHPHG_02691 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NIPEHPHG_02692 1.5e-164 yvoD P COG0370 Fe2 transport system protein B
NIPEHPHG_02693 1.3e-119 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NIPEHPHG_02694 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
NIPEHPHG_02695 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
NIPEHPHG_02696 4.5e-140 yvpB NU protein conserved in bacteria
NIPEHPHG_02697 4.8e-221 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NIPEHPHG_02698 1.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NIPEHPHG_02699 6.6e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NIPEHPHG_02700 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NIPEHPHG_02701 1.7e-116 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NIPEHPHG_02702 3.1e-133 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NIPEHPHG_02703 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NIPEHPHG_02704 8e-114 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
NIPEHPHG_02705 4.6e-121
NIPEHPHG_02706 0.0
NIPEHPHG_02708 0.0 msbA2 3.6.3.44 V ABC transporter
NIPEHPHG_02709 2.4e-278 S COG0457 FOG TPR repeat
NIPEHPHG_02710 1.4e-102 usp CBM50 M protein conserved in bacteria
NIPEHPHG_02711 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NIPEHPHG_02712 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NIPEHPHG_02713 5.7e-166 rapZ S Displays ATPase and GTPase activities
NIPEHPHG_02714 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NIPEHPHG_02715 1.4e-170 whiA K May be required for sporulation
NIPEHPHG_02716 1.6e-36 crh G Phosphocarrier protein Chr
NIPEHPHG_02717 8.6e-147 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
NIPEHPHG_02718 1.8e-33
NIPEHPHG_02719 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NIPEHPHG_02720 2.3e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
NIPEHPHG_02721 5.6e-141 yvcR V ABC transporter, ATP-binding protein
NIPEHPHG_02722 0.0 yxdM V ABC transporter (permease)
NIPEHPHG_02723 1.3e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIPEHPHG_02724 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NIPEHPHG_02725 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
NIPEHPHG_02726 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
NIPEHPHG_02727 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
NIPEHPHG_02728 3.6e-174 yvdE K Transcriptional regulator
NIPEHPHG_02729 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
NIPEHPHG_02730 1.3e-235 mdxE G COG2182 Maltose-binding periplasmic proteins domains
NIPEHPHG_02731 5.3e-245 malC P COG1175 ABC-type sugar transport systems, permease components
NIPEHPHG_02732 7.8e-149 malD P transport
NIPEHPHG_02733 1.2e-158 malA S Protein of unknown function (DUF1189)
NIPEHPHG_02734 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
NIPEHPHG_02735 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
NIPEHPHG_02736 1.3e-122 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
NIPEHPHG_02737 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NIPEHPHG_02739 1.5e-183 S Patatin-like phospholipase
NIPEHPHG_02740 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
NIPEHPHG_02741 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
NIPEHPHG_02742 4.1e-50 sugE P Small Multidrug Resistance protein
NIPEHPHG_02743 6.7e-51 ykkC P Small Multidrug Resistance protein
NIPEHPHG_02744 2.6e-106 yvdT K Transcriptional regulator
NIPEHPHG_02745 1.8e-295 yveA E amino acid
NIPEHPHG_02746 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NIPEHPHG_02747 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
NIPEHPHG_02748 9.6e-266 pbpE V Beta-lactamase
NIPEHPHG_02749 3.1e-127 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NIPEHPHG_02750 1.3e-48 MA20_18690 S Protein of unknown function (DUF3237)
NIPEHPHG_02751 4.6e-93 padC Q Phenolic acid decarboxylase
NIPEHPHG_02753 4.8e-287 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
NIPEHPHG_02754 5.7e-77 slr K transcriptional
NIPEHPHG_02755 4e-122 ywqC M biosynthesis protein
NIPEHPHG_02756 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
NIPEHPHG_02757 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
NIPEHPHG_02758 2e-224 epsD GT4 M Glycosyl transferase 4-like
NIPEHPHG_02759 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NIPEHPHG_02760 5.3e-220 epsF GT4 M Glycosyl transferases group 1
NIPEHPHG_02761 4.8e-207 epsG S EpsG family
NIPEHPHG_02762 3.6e-196 epsH GT2 S Glycosyltransferase like family 2
NIPEHPHG_02763 3.6e-207 epsI GM pyruvyl transferase
NIPEHPHG_02764 1.9e-197 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
NIPEHPHG_02765 8.9e-260 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NIPEHPHG_02766 2.6e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NIPEHPHG_02767 2.2e-58 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
NIPEHPHG_02768 1.2e-224 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
NIPEHPHG_02769 5.8e-188 yvfF GM Exopolysaccharide biosynthesis protein
NIPEHPHG_02770 1e-31 yvfG S YvfG protein
NIPEHPHG_02771 6.5e-243 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NIPEHPHG_02772 1.4e-309 yvfH C L-lactate permease
NIPEHPHG_02773 1e-112 yvfI K COG2186 Transcriptional regulators
NIPEHPHG_02774 1.8e-184 lacR K Transcriptional regulator
NIPEHPHG_02775 2.9e-232 cycB G COG2182 Maltose-binding periplasmic proteins domains
NIPEHPHG_02776 1.3e-232 malC P COG1175 ABC-type sugar transport systems, permease components
NIPEHPHG_02777 3.2e-150 ganQ P transport
NIPEHPHG_02778 0.0 lacA 3.2.1.23 G beta-galactosidase
NIPEHPHG_02779 2.6e-252 galA 3.2.1.89 G arabinogalactan
NIPEHPHG_02780 1.4e-199 rsbU 3.1.3.3 T response regulator
NIPEHPHG_02781 2.6e-157 rsbQ S Alpha/beta hydrolase family
NIPEHPHG_02782 3e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
NIPEHPHG_02783 6.2e-134 yvfS V COG0842 ABC-type multidrug transport system, permease component
NIPEHPHG_02784 8.9e-201 desK 2.7.13.3 T Histidine kinase
NIPEHPHG_02785 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NIPEHPHG_02786 1.5e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NIPEHPHG_02787 1.2e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NIPEHPHG_02788 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NIPEHPHG_02789 4.3e-197 yvbX S Glycosyl hydrolase
NIPEHPHG_02790 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
NIPEHPHG_02791 8.5e-157 yvbV EG EamA-like transporter family
NIPEHPHG_02792 3.9e-159 yvbU K Transcriptional regulator
NIPEHPHG_02793 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NIPEHPHG_02794 5.5e-203 araR K transcriptional
NIPEHPHG_02795 1.6e-252 araE EGP Major facilitator Superfamily
NIPEHPHG_02796 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NIPEHPHG_02797 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NIPEHPHG_02798 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NIPEHPHG_02799 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NIPEHPHG_02800 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
NIPEHPHG_02801 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NIPEHPHG_02802 7.7e-82 yvbK 3.1.3.25 K acetyltransferase
NIPEHPHG_02803 0.0 tcaA S response to antibiotic
NIPEHPHG_02804 4.2e-124 exoY M Membrane
NIPEHPHG_02805 8.6e-113 yvbH S YvbH-like oligomerisation region
NIPEHPHG_02806 6.4e-103 yvbG U UPF0056 membrane protein
NIPEHPHG_02807 1.4e-98 yvbF K Belongs to the GbsR family
NIPEHPHG_02808 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NIPEHPHG_02809 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NIPEHPHG_02810 2.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NIPEHPHG_02811 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NIPEHPHG_02812 4.5e-45 sdpR K transcriptional
NIPEHPHG_02813 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
NIPEHPHG_02814 4.4e-08
NIPEHPHG_02815 2.2e-171
NIPEHPHG_02816 7.9e-13 S Sporulation delaying protein SdpA
NIPEHPHG_02817 8.7e-61 yvbF K Belongs to the GbsR family
NIPEHPHG_02818 3e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NIPEHPHG_02819 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NIPEHPHG_02820 1.1e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NIPEHPHG_02821 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NIPEHPHG_02822 4.2e-226 NT chemotaxis protein
NIPEHPHG_02823 2.2e-54 yodB K transcriptional
NIPEHPHG_02824 8e-70 yvaO K Cro/C1-type HTH DNA-binding domain
NIPEHPHG_02825 4e-69 K transcriptional
NIPEHPHG_02826 7.5e-36 yvzC K Transcriptional
NIPEHPHG_02827 3.7e-153 yvaM S Serine aminopeptidase, S33
NIPEHPHG_02828 2.4e-23 secG U Preprotein translocase subunit SecG
NIPEHPHG_02829 5.6e-143 est 3.1.1.1 S Carboxylesterase
NIPEHPHG_02830 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NIPEHPHG_02831 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NIPEHPHG_02833 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NIPEHPHG_02834 4.1e-101 K Bacterial regulatory proteins, tetR family
NIPEHPHG_02835 2.8e-55 yvaE P Small Multidrug Resistance protein
NIPEHPHG_02836 5.7e-73 yvaD S Family of unknown function (DUF5360)
NIPEHPHG_02837 0.0 yvaC S Fusaric acid resistance protein-like
NIPEHPHG_02838 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NIPEHPHG_02839 2.1e-199 yvaA 1.1.1.371 S Oxidoreductase
NIPEHPHG_02840 2.2e-48 csoR S transcriptional
NIPEHPHG_02841 1.5e-29 copZ P Copper resistance protein CopZ
NIPEHPHG_02842 0.0 copA 3.6.3.54 P P-type ATPase
NIPEHPHG_02843 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NIPEHPHG_02844 1.6e-104 bdbD O Thioredoxin
NIPEHPHG_02845 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
NIPEHPHG_02846 4.1e-107 yvgT S membrane
NIPEHPHG_02847 0.0 helD 3.6.4.12 L DNA helicase
NIPEHPHG_02848 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NIPEHPHG_02849 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NIPEHPHG_02850 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
NIPEHPHG_02851 5.4e-86 yvgO
NIPEHPHG_02852 9.1e-158 yvgN S reductase
NIPEHPHG_02853 4.7e-120 modB P COG4149 ABC-type molybdate transport system, permease component
NIPEHPHG_02854 5.8e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
NIPEHPHG_02855 8e-171 yvgK P COG1910 Periplasmic molybdate-binding protein domain
NIPEHPHG_02856 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NIPEHPHG_02857 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
NIPEHPHG_02858 6.5e-16 S Small spore protein J (Spore_SspJ)
NIPEHPHG_02859 2.6e-237 yvsH E Arginine ornithine antiporter
NIPEHPHG_02861 2.1e-179 fhuD P ABC transporter
NIPEHPHG_02862 9.3e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIPEHPHG_02863 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIPEHPHG_02864 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
NIPEHPHG_02865 4.8e-176 M Efflux transporter rnd family, mfp subunit
NIPEHPHG_02866 7.1e-124 macB V ABC transporter, ATP-binding protein
NIPEHPHG_02867 1.8e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
NIPEHPHG_02868 1.3e-64 yvrL S Regulatory protein YrvL
NIPEHPHG_02869 7.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
NIPEHPHG_02870 2.4e-19 S YvrJ protein family
NIPEHPHG_02871 1.8e-96 yvrI K RNA polymerase
NIPEHPHG_02872 3.6e-22
NIPEHPHG_02873 3.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NIPEHPHG_02874 0.0 T PhoQ Sensor
NIPEHPHG_02875 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
NIPEHPHG_02876 6.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NIPEHPHG_02877 1.8e-170 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NIPEHPHG_02878 7.7e-186 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIPEHPHG_02879 2.8e-249 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NIPEHPHG_02880 6.5e-102 yvqK 2.5.1.17 S Adenosyltransferase
NIPEHPHG_02881 4.8e-227 yvqJ EGP Major facilitator Superfamily
NIPEHPHG_02882 5.6e-62 liaI S membrane
NIPEHPHG_02883 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NIPEHPHG_02884 9.3e-129 liaG S Putative adhesin
NIPEHPHG_02885 5.6e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
NIPEHPHG_02886 5.5e-187 vraS 2.7.13.3 T Histidine kinase
NIPEHPHG_02887 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NIPEHPHG_02888 6e-189 gerAC S Spore germination B3/ GerAC like, C-terminal
NIPEHPHG_02889 9.1e-198 gerAB E Spore germination protein
NIPEHPHG_02890 3.7e-247 gerAA EG Spore germination protein
NIPEHPHG_02891 2.3e-24 S Protein of unknown function (DUF3970)
NIPEHPHG_02892 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NIPEHPHG_02893 4.3e-158 yuxN K Transcriptional regulator
NIPEHPHG_02894 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
NIPEHPHG_02895 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NIPEHPHG_02896 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NIPEHPHG_02897 1.2e-79 dps P Ferritin-like domain
NIPEHPHG_02898 4.7e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NIPEHPHG_02899 3.9e-34 pepF2 E COG1164 Oligoendopeptidase F
NIPEHPHG_02900 6.3e-258 pepF2 E COG1164 Oligoendopeptidase F
NIPEHPHG_02901 5.6e-66 S YusW-like protein
NIPEHPHG_02902 1e-153 yusV 3.6.3.34 HP ABC transporter
NIPEHPHG_02903 3.8e-47 yusU S Protein of unknown function (DUF2573)
NIPEHPHG_02904 2.7e-160 yusT K LysR substrate binding domain
NIPEHPHG_02905 2.5e-50 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NIPEHPHG_02906 2.5e-62 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NIPEHPHG_02907 8.4e-66 yusQ S Tautomerase enzyme
NIPEHPHG_02908 3.8e-293 yusP P Major facilitator superfamily
NIPEHPHG_02909 5.4e-75 yusO K Iron dependent repressor, N-terminal DNA binding domain
NIPEHPHG_02910 3.2e-53 yusN M Coat F domain
NIPEHPHG_02911 5.1e-40
NIPEHPHG_02912 2.2e-165 fadM E Proline dehydrogenase
NIPEHPHG_02913 4.7e-09 S YuzL-like protein
NIPEHPHG_02914 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
NIPEHPHG_02915 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
NIPEHPHG_02916 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
NIPEHPHG_02917 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
NIPEHPHG_02918 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NIPEHPHG_02919 1.1e-39 yusG S Protein of unknown function (DUF2553)
NIPEHPHG_02920 3.3e-74 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
NIPEHPHG_02921 5.6e-55 traF CO Thioredoxin
NIPEHPHG_02922 2.4e-56 yusD S SCP-2 sterol transfer family
NIPEHPHG_02923 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NIPEHPHG_02924 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
NIPEHPHG_02925 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
NIPEHPHG_02926 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NIPEHPHG_02927 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NIPEHPHG_02928 1.4e-245 sufD O assembly protein SufD
NIPEHPHG_02929 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NIPEHPHG_02930 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
NIPEHPHG_02931 3.5e-271 sufB O FeS cluster assembly
NIPEHPHG_02932 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NIPEHPHG_02933 1e-41
NIPEHPHG_02935 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
NIPEHPHG_02936 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
NIPEHPHG_02937 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NIPEHPHG_02938 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
NIPEHPHG_02939 1.4e-156 yurN G Binding-protein-dependent transport system inner membrane component
NIPEHPHG_02940 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
NIPEHPHG_02941 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
NIPEHPHG_02942 1.1e-135 yurK K UTRA
NIPEHPHG_02943 1.2e-205 msmX P Belongs to the ABC transporter superfamily
NIPEHPHG_02944 2.4e-169 bsn L Ribonuclease
NIPEHPHG_02945 1.6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NIPEHPHG_02946 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NIPEHPHG_02948 1.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NIPEHPHG_02949 3.6e-111 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
NIPEHPHG_02950 3.4e-152 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NIPEHPHG_02951 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NIPEHPHG_02952 1.8e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NIPEHPHG_02953 2.7e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
NIPEHPHG_02954 7.3e-283 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
NIPEHPHG_02955 1.3e-222 pbuX F xanthine
NIPEHPHG_02956 2.1e-236 pbuX F Permease family
NIPEHPHG_02957 1.2e-302 pucR QT COG2508 Regulator of polyketide synthase expression
NIPEHPHG_02958 1e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NIPEHPHG_02959 3e-62 yunG
NIPEHPHG_02960 4.3e-171 yunF S Protein of unknown function DUF72
NIPEHPHG_02961 2e-141 yunE S membrane transporter protein
NIPEHPHG_02962 5.8e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NIPEHPHG_02963 4.8e-48 yunC S Domain of unknown function (DUF1805)
NIPEHPHG_02964 8.4e-134 yunB S Sporulation protein YunB (Spo_YunB)
NIPEHPHG_02965 4.5e-196 lytH M Peptidase, M23
NIPEHPHG_02966 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NIPEHPHG_02967 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NIPEHPHG_02968 9.7e-48 yutD S protein conserved in bacteria
NIPEHPHG_02969 1e-75 yutE S Protein of unknown function DUF86
NIPEHPHG_02970 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NIPEHPHG_02971 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NIPEHPHG_02972 2e-199 yutH S Spore coat protein
NIPEHPHG_02973 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
NIPEHPHG_02974 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NIPEHPHG_02975 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NIPEHPHG_02976 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
NIPEHPHG_02977 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
NIPEHPHG_02978 3.5e-57 yuzD S protein conserved in bacteria
NIPEHPHG_02979 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
NIPEHPHG_02980 3.2e-39 yuzB S Belongs to the UPF0349 family
NIPEHPHG_02981 2.4e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NIPEHPHG_02982 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NIPEHPHG_02983 3.7e-63 erpA S Belongs to the HesB IscA family
NIPEHPHG_02984 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NIPEHPHG_02985 9e-118 paiB K Putative FMN-binding domain
NIPEHPHG_02986 4.9e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NIPEHPHG_02988 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
NIPEHPHG_02989 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
NIPEHPHG_02990 8.4e-27 yuiB S Putative membrane protein
NIPEHPHG_02991 9.5e-118 yuiC S protein conserved in bacteria
NIPEHPHG_02992 1.2e-77 yuiD S protein conserved in bacteria
NIPEHPHG_02993 1.5e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NIPEHPHG_02994 3.9e-211 yuiF S antiporter
NIPEHPHG_02995 1.1e-93 bioY S Biotin biosynthesis protein
NIPEHPHG_02996 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
NIPEHPHG_02997 1.3e-167 besA S Putative esterase
NIPEHPHG_02998 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NIPEHPHG_02999 2.3e-226 entC 5.4.4.2 HQ Isochorismate synthase
NIPEHPHG_03000 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
NIPEHPHG_03001 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
NIPEHPHG_03002 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIPEHPHG_03003 3.8e-36 mbtH S MbtH-like protein
NIPEHPHG_03004 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
NIPEHPHG_03005 1.2e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
NIPEHPHG_03006 6.5e-229 yukF QT Transcriptional regulator
NIPEHPHG_03007 2.8e-45 esxA S Belongs to the WXG100 family
NIPEHPHG_03008 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
NIPEHPHG_03009 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
NIPEHPHG_03010 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NIPEHPHG_03011 0.0 esaA S type VII secretion protein EsaA
NIPEHPHG_03012 6.6e-65 yueC S Family of unknown function (DUF5383)
NIPEHPHG_03013 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NIPEHPHG_03014 4.8e-96 yueE S phosphohydrolase
NIPEHPHG_03015 2.9e-24 S Protein of unknown function (DUF2642)
NIPEHPHG_03016 6.1e-72 S Protein of unknown function (DUF2283)
NIPEHPHG_03017 1.9e-190 yueF S transporter activity
NIPEHPHG_03018 2.1e-32 yueG S Spore germination protein gerPA/gerPF
NIPEHPHG_03019 7.4e-39 yueH S YueH-like protein
NIPEHPHG_03020 1.6e-67 yueI S Protein of unknown function (DUF1694)
NIPEHPHG_03021 2.9e-104 pncA Q COG1335 Amidases related to nicotinamidase
NIPEHPHG_03022 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NIPEHPHG_03023 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
NIPEHPHG_03024 1.1e-22 yuzC
NIPEHPHG_03026 2.5e-162 comQ H Polyprenyl synthetase
NIPEHPHG_03028 0.0 comP 2.7.13.3 T Histidine kinase
NIPEHPHG_03029 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NIPEHPHG_03030 9.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
NIPEHPHG_03031 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
NIPEHPHG_03032 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NIPEHPHG_03033 4.8e-79 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NIPEHPHG_03034 3.8e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NIPEHPHG_03035 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NIPEHPHG_03036 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NIPEHPHG_03037 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NIPEHPHG_03038 1.9e-14
NIPEHPHG_03039 1.3e-233 maeN C COG3493 Na citrate symporter
NIPEHPHG_03040 4.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
NIPEHPHG_03041 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
NIPEHPHG_03042 1.1e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NIPEHPHG_03043 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
NIPEHPHG_03044 2.3e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
NIPEHPHG_03045 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NIPEHPHG_03046 6.3e-78 yufK S Family of unknown function (DUF5366)
NIPEHPHG_03047 6.3e-75 yuxK S protein conserved in bacteria
NIPEHPHG_03048 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
NIPEHPHG_03049 3.5e-186 yuxJ EGP Major facilitator Superfamily
NIPEHPHG_03051 1.9e-115 kapD L the KinA pathway to sporulation
NIPEHPHG_03052 2e-70 kapB G Kinase associated protein B
NIPEHPHG_03053 4.6e-233 T PhoQ Sensor
NIPEHPHG_03054 1.8e-228 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NIPEHPHG_03055 9.8e-42 yugE S Domain of unknown function (DUF1871)
NIPEHPHG_03056 1e-156 yugF I Hydrolase
NIPEHPHG_03057 1.6e-85 alaR K Transcriptional regulator
NIPEHPHG_03058 4.3e-200 yugH 2.6.1.1 E Aminotransferase
NIPEHPHG_03059 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
NIPEHPHG_03060 1.1e-34 yuzA S Domain of unknown function (DUF378)
NIPEHPHG_03061 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
NIPEHPHG_03062 2.8e-229 yugK C Dehydrogenase
NIPEHPHG_03063 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
NIPEHPHG_03065 1.3e-72 yugN S YugN-like family
NIPEHPHG_03066 1.7e-182 yugO P COG1226 Kef-type K transport systems
NIPEHPHG_03067 1.1e-53 mstX S Membrane-integrating protein Mistic
NIPEHPHG_03068 4.6e-39
NIPEHPHG_03069 1.4e-116 yugP S Zn-dependent protease
NIPEHPHG_03070 2.6e-236 yugS S COG1253 Hemolysins and related proteins containing CBS domains
NIPEHPHG_03071 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
NIPEHPHG_03072 2.1e-72 yugU S Uncharacterised protein family UPF0047
NIPEHPHG_03073 1e-35
NIPEHPHG_03074 2.6e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
NIPEHPHG_03075 3.2e-225 mcpA NT chemotaxis protein
NIPEHPHG_03076 1.5e-222 mcpA NT chemotaxis protein
NIPEHPHG_03077 2.2e-295 mcpA NT chemotaxis protein
NIPEHPHG_03078 5.1e-239 mcpA NT chemotaxis protein
NIPEHPHG_03079 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
NIPEHPHG_03080 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
NIPEHPHG_03081 1.3e-281 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NIPEHPHG_03082 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
NIPEHPHG_03083 1.4e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
NIPEHPHG_03084 3.3e-183 ygjR S Oxidoreductase
NIPEHPHG_03085 6.3e-197 yubA S transporter activity
NIPEHPHG_03086 1.2e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NIPEHPHG_03088 2.6e-88 cdoA 1.13.11.20 S Cysteine dioxygenase type I
NIPEHPHG_03089 6.2e-277 yubD P Major Facilitator Superfamily
NIPEHPHG_03090 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NIPEHPHG_03091 1e-38 yiaA S yiaA/B two helix domain
NIPEHPHG_03092 5.4e-237 ktrB P Potassium
NIPEHPHG_03093 5e-122 ktrA P COG0569 K transport systems, NAD-binding component
NIPEHPHG_03094 2.2e-91 yuaB
NIPEHPHG_03095 1.1e-95 yuaC K Belongs to the GbsR family
NIPEHPHG_03096 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
NIPEHPHG_03097 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
NIPEHPHG_03098 7.9e-108 yuaD
NIPEHPHG_03099 3.9e-84 yuaE S DinB superfamily
NIPEHPHG_03100 1.4e-77 yuaF OU Membrane protein implicated in regulation of membrane protease activity
NIPEHPHG_03101 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
NIPEHPHG_03102 3.4e-94 M1-753 M FR47-like protein
NIPEHPHG_03103 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
NIPEHPHG_03104 6.7e-167 ygxA S Nucleotidyltransferase-like
NIPEHPHG_03105 1.5e-56 ygzB S UPF0295 protein
NIPEHPHG_03106 4e-80 perR P Belongs to the Fur family
NIPEHPHG_03107 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
NIPEHPHG_03108 1.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NIPEHPHG_03109 8.7e-180 ygaE S Membrane
NIPEHPHG_03110 1.8e-301 ygaD V ABC transporter
NIPEHPHG_03111 1.3e-104 ygaC J Belongs to the UPF0374 family
NIPEHPHG_03112 1.5e-37 ygaB S YgaB-like protein
NIPEHPHG_03113 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
NIPEHPHG_03114 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NIPEHPHG_03115 6.9e-36 yfhS
NIPEHPHG_03116 7.8e-212 mutY L A G-specific
NIPEHPHG_03117 5.5e-186 yfhP S membrane-bound metal-dependent
NIPEHPHG_03118 0.0 yfhO S Bacterial membrane protein YfhO
NIPEHPHG_03119 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NIPEHPHG_03120 6.7e-172 yfhM S Alpha beta hydrolase
NIPEHPHG_03121 3.5e-51 yfhL S SdpI/YhfL protein family
NIPEHPHG_03122 9.2e-92 batE T Bacterial SH3 domain homologues
NIPEHPHG_03123 1.3e-44 yfhJ S WVELL protein
NIPEHPHG_03124 4e-19 sspK S reproduction
NIPEHPHG_03125 1.1e-209 yfhI EGP Major facilitator Superfamily
NIPEHPHG_03127 9.7e-52 yfhH S Protein of unknown function (DUF1811)
NIPEHPHG_03128 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
NIPEHPHG_03129 4.9e-173 yfhF S nucleoside-diphosphate sugar epimerase
NIPEHPHG_03131 2.1e-25 yfhD S YfhD-like protein
NIPEHPHG_03132 3.9e-107 yfhC C nitroreductase
NIPEHPHG_03133 1.8e-167 yfhB 5.3.3.17 S PhzF family
NIPEHPHG_03134 5.2e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIPEHPHG_03135 3.1e-176 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIPEHPHG_03136 6.2e-182 yfiY P ABC transporter substrate-binding protein
NIPEHPHG_03137 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NIPEHPHG_03138 3.1e-81 yfiV K transcriptional
NIPEHPHG_03139 8.7e-287 yfiU EGP Major facilitator Superfamily
NIPEHPHG_03140 3.3e-100 yfiT S Belongs to the metal hydrolase YfiT family
NIPEHPHG_03141 5.1e-221 yfiS EGP Major facilitator Superfamily
NIPEHPHG_03142 2e-109 yfiR K Transcriptional regulator
NIPEHPHG_03143 9e-198 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NIPEHPHG_03144 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NIPEHPHG_03145 8.3e-99 padR K transcriptional
NIPEHPHG_03146 4.6e-208 V COG0842 ABC-type multidrug transport system, permease component
NIPEHPHG_03147 9.8e-214 V ABC-2 family transporter protein
NIPEHPHG_03148 6.2e-171 V ABC transporter, ATP-binding protein
NIPEHPHG_03149 3.2e-113 KT LuxR family transcriptional regulator
NIPEHPHG_03150 1.1e-214 yxjM T Histidine kinase
NIPEHPHG_03152 1.1e-233 S Oxidoreductase
NIPEHPHG_03153 8.4e-184 G Xylose isomerase
NIPEHPHG_03154 1.8e-262 iolT EGP Major facilitator Superfamily
NIPEHPHG_03155 1.5e-177 K AraC-like ligand binding domain
NIPEHPHG_03156 5.7e-163 yfiE 1.13.11.2 S glyoxalase
NIPEHPHG_03157 9.8e-65 mhqP S DoxX
NIPEHPHG_03158 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
NIPEHPHG_03159 2.1e-310 yfiB3 V ABC transporter
NIPEHPHG_03160 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NIPEHPHG_03161 3.2e-141 glvR K Helix-turn-helix domain, rpiR family
NIPEHPHG_03162 9.9e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NIPEHPHG_03163 1.1e-44 yfjA S Belongs to the WXG100 family
NIPEHPHG_03164 9.2e-191 yfjB
NIPEHPHG_03165 4.1e-144 yfjC
NIPEHPHG_03166 1.8e-101 yfjD S Family of unknown function (DUF5381)
NIPEHPHG_03167 1.3e-80 S Family of unknown function (DUF5381)
NIPEHPHG_03168 4e-56 yfjF S UPF0060 membrane protein
NIPEHPHG_03169 1.2e-25 sspH S Belongs to the SspH family
NIPEHPHG_03170 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
NIPEHPHG_03171 6.4e-257 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NIPEHPHG_03172 2.9e-197 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NIPEHPHG_03173 1e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NIPEHPHG_03174 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NIPEHPHG_03175 3e-29 yfjL
NIPEHPHG_03176 3.9e-86 yfjM S Psort location Cytoplasmic, score
NIPEHPHG_03177 5.1e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NIPEHPHG_03178 1.6e-39 S YfzA-like protein
NIPEHPHG_03179 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NIPEHPHG_03180 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NIPEHPHG_03181 1.7e-184 corA P Mediates influx of magnesium ions
NIPEHPHG_03182 4.2e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NIPEHPHG_03183 2.6e-154 pdaA G deacetylase
NIPEHPHG_03184 1.1e-26 yfjT
NIPEHPHG_03185 5.4e-222 yfkA S YfkB-like domain
NIPEHPHG_03186 6e-149 yfkC M Mechanosensitive ion channel
NIPEHPHG_03187 1.2e-146 yfkD S YfkD-like protein
NIPEHPHG_03188 6.1e-183 cax P COG0387 Ca2 H antiporter
NIPEHPHG_03189 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
NIPEHPHG_03190 5e-08
NIPEHPHG_03191 9.7e-144 yihY S Belongs to the UPF0761 family
NIPEHPHG_03192 8.4e-51 yfkI S gas vesicle protein
NIPEHPHG_03193 2.2e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NIPEHPHG_03194 2.1e-29 yfkK S Belongs to the UPF0435 family
NIPEHPHG_03195 6.8e-207 ydiM EGP Major facilitator Superfamily
NIPEHPHG_03196 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
NIPEHPHG_03197 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NIPEHPHG_03198 1.6e-125 yfkO C nitroreductase
NIPEHPHG_03199 1.8e-133 treR K transcriptional
NIPEHPHG_03200 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NIPEHPHG_03201 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NIPEHPHG_03202 1.5e-283 yfkQ EG Spore germination protein
NIPEHPHG_03203 5.1e-207 yfkR S spore germination
NIPEHPHG_03205 1.6e-194 E Spore germination protein
NIPEHPHG_03206 3.2e-256 agcS_1 E Sodium alanine symporter
NIPEHPHG_03207 6e-67 yhdN S Domain of unknown function (DUF1992)
NIPEHPHG_03208 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NIPEHPHG_03209 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NIPEHPHG_03210 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
NIPEHPHG_03211 2.4e-50 yflH S Protein of unknown function (DUF3243)
NIPEHPHG_03212 4.1e-19 yflI
NIPEHPHG_03213 4e-18 yflJ S Protein of unknown function (DUF2639)
NIPEHPHG_03214 9e-124 yflK S protein conserved in bacteria
NIPEHPHG_03215 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NIPEHPHG_03216 1.3e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NIPEHPHG_03217 5.5e-152 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
NIPEHPHG_03218 8.5e-227 citM C Citrate transporter
NIPEHPHG_03220 3e-181 yflP S Tripartite tricarboxylate transporter family receptor
NIPEHPHG_03221 8.9e-119 citT T response regulator
NIPEHPHG_03222 1e-290 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NIPEHPHG_03223 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
NIPEHPHG_03224 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
NIPEHPHG_03225 7.6e-58 yflT S Heat induced stress protein YflT
NIPEHPHG_03226 2.9e-24 S Protein of unknown function (DUF3212)
NIPEHPHG_03227 3.4e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
NIPEHPHG_03228 4.3e-170 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIPEHPHG_03229 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIPEHPHG_03230 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
NIPEHPHG_03231 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
NIPEHPHG_03232 7.7e-214 G Major Facilitator Superfamily
NIPEHPHG_03233 8.5e-190 yfmJ S N-terminal domain of oxidoreductase
NIPEHPHG_03234 7.5e-82 yfmK 2.3.1.128 K acetyltransferase
NIPEHPHG_03235 6.3e-202 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
NIPEHPHG_03236 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NIPEHPHG_03237 1.5e-209 yfmO EGP Major facilitator Superfamily
NIPEHPHG_03238 2.8e-70 yfmP K transcriptional
NIPEHPHG_03239 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
NIPEHPHG_03240 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NIPEHPHG_03241 1.1e-113 yfmS NT chemotaxis protein
NIPEHPHG_03242 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NIPEHPHG_03243 1.3e-241 yfnA E amino acid
NIPEHPHG_03244 7.8e-134 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NIPEHPHG_03245 2e-206 fsr P COG0477 Permeases of the major facilitator superfamily
NIPEHPHG_03246 3.5e-190 yfnD M Nucleotide-diphospho-sugar transferase
NIPEHPHG_03247 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
NIPEHPHG_03248 3.8e-181 yfnF M Nucleotide-diphospho-sugar transferase
NIPEHPHG_03249 1.9e-172 yfnG 4.2.1.45 M dehydratase
NIPEHPHG_03250 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
NIPEHPHG_03251 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NIPEHPHG_03252 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NIPEHPHG_03253 3.6e-199 yetN S Protein of unknown function (DUF3900)
NIPEHPHG_03254 7.8e-213 yetM CH FAD binding domain
NIPEHPHG_03255 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
NIPEHPHG_03256 5.4e-159 yetK EG EamA-like transporter family
NIPEHPHG_03257 5.3e-105 yetJ S Belongs to the BI1 family
NIPEHPHG_03258 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
NIPEHPHG_03259 4.4e-43 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NIPEHPHG_03260 2.2e-89 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NIPEHPHG_03261 2.2e-34
NIPEHPHG_03262 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NIPEHPHG_03263 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
NIPEHPHG_03264 6.1e-123 yetF S membrane
NIPEHPHG_03265 3.3e-258 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NIPEHPHG_03266 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
NIPEHPHG_03267 1.3e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NIPEHPHG_03268 9.6e-291 lplA G Bacterial extracellular solute-binding protein
NIPEHPHG_03269 0.0 yetA
NIPEHPHG_03270 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
NIPEHPHG_03271 3e-124 yesY E GDSL-like Lipase/Acylhydrolase
NIPEHPHG_03272 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NIPEHPHG_03273 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NIPEHPHG_03274 1e-113 yesV S Protein of unknown function, DUF624
NIPEHPHG_03275 8.9e-132 yesU S Domain of unknown function (DUF1961)
NIPEHPHG_03276 3.8e-133 E GDSL-like Lipase/Acylhydrolase
NIPEHPHG_03277 0.0 yesS K Transcriptional regulator
NIPEHPHG_03278 1.6e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
NIPEHPHG_03279 1.3e-165 yesQ P Binding-protein-dependent transport system inner membrane component
NIPEHPHG_03280 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
NIPEHPHG_03281 5e-248 yesO G Bacterial extracellular solute-binding protein
NIPEHPHG_03282 2.9e-204 yesN K helix_turn_helix, arabinose operon control protein
NIPEHPHG_03283 0.0 yesM 2.7.13.3 T Histidine kinase
NIPEHPHG_03284 4.4e-104 yesL S Protein of unknown function, DUF624
NIPEHPHG_03286 4.2e-103 yesJ K Acetyltransferase (GNAT) family
NIPEHPHG_03287 5.2e-104 cotJC P Spore Coat
NIPEHPHG_03288 1.5e-45 cotJB S CotJB protein
NIPEHPHG_03289 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
NIPEHPHG_03290 2.2e-159 yesF GM NAD(P)H-binding
NIPEHPHG_03291 9.7e-82 yesE S SnoaL-like domain
NIPEHPHG_03292 1.2e-103 dhaR3 K Transcriptional regulator
NIPEHPHG_03294 9.4e-127 yeeN K transcriptional regulatory protein
NIPEHPHG_03296 5.5e-214 S Tetratricopeptide repeat
NIPEHPHG_03297 1.8e-192 3.4.24.40 CO amine dehydrogenase activity
NIPEHPHG_03298 0.0 L nucleic acid phosphodiester bond hydrolysis
NIPEHPHG_03299 5.5e-83 S Protein of unknown function, DUF600
NIPEHPHG_03300 6.2e-31 S Colicin immunity protein / pyocin immunity protein
NIPEHPHG_03302 1.2e-211 pstS P T5orf172
NIPEHPHG_03303 0.0 yeeB L DEAD-like helicases superfamily
NIPEHPHG_03304 0.0 yeeA V Type II restriction enzyme, methylase subunits
NIPEHPHG_03305 3.2e-53 L Resolvase, N terminal domain
NIPEHPHG_03306 3.2e-98 L Recombinase
NIPEHPHG_03307 1.2e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NIPEHPHG_03308 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NIPEHPHG_03309 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NIPEHPHG_03310 4e-156 yerO K Transcriptional regulator
NIPEHPHG_03311 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIPEHPHG_03312 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NIPEHPHG_03313 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIPEHPHG_03314 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NIPEHPHG_03315 1.6e-123 sapB S MgtC SapB transporter
NIPEHPHG_03316 1.1e-197 yerI S homoserine kinase type II (protein kinase fold)
NIPEHPHG_03317 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
NIPEHPHG_03318 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NIPEHPHG_03319 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NIPEHPHG_03320 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NIPEHPHG_03322 3.2e-305 yerD 1.4.7.1 E Belongs to the glutamate synthase family
NIPEHPHG_03323 4.8e-51 yerC S protein conserved in bacteria
NIPEHPHG_03324 3e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
NIPEHPHG_03325 0.0 yerA 3.5.4.2 F adenine deaminase
NIPEHPHG_03326 2.7e-27 S Protein of unknown function (DUF2892)
NIPEHPHG_03327 2.3e-232 yjeH E Amino acid permease
NIPEHPHG_03328 3.5e-73 K helix_turn_helix ASNC type
NIPEHPHG_03329 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
NIPEHPHG_03330 3.5e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NIPEHPHG_03331 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NIPEHPHG_03332 3.2e-176 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NIPEHPHG_03333 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NIPEHPHG_03334 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NIPEHPHG_03335 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NIPEHPHG_03336 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NIPEHPHG_03337 1.2e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NIPEHPHG_03338 2.1e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NIPEHPHG_03339 7e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NIPEHPHG_03340 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NIPEHPHG_03341 8e-28 yebG S NETI protein
NIPEHPHG_03342 4e-93 yebE S UPF0316 protein
NIPEHPHG_03344 1.1e-118 yebC M Membrane
NIPEHPHG_03345 6e-212 pbuG S permease
NIPEHPHG_03346 9.8e-256 S Domain of unknown function (DUF4179)
NIPEHPHG_03347 2e-89 K Belongs to the sigma-70 factor family. ECF subfamily
NIPEHPHG_03348 3.7e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NIPEHPHG_03349 0.0 yebA E COG1305 Transglutaminase-like enzymes
NIPEHPHG_03350 9.5e-225 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NIPEHPHG_03351 1.6e-177 yeaC S COG0714 MoxR-like ATPases
NIPEHPHG_03352 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NIPEHPHG_03353 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
NIPEHPHG_03354 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
NIPEHPHG_03355 3.3e-175 yeaA S Protein of unknown function (DUF4003)
NIPEHPHG_03356 8.4e-156 ydjP I Alpha/beta hydrolase family
NIPEHPHG_03357 1.4e-34 ydjO S Cold-inducible protein YdjO
NIPEHPHG_03359 2.3e-150 ydjN U Involved in the tonB-independent uptake of proteins
NIPEHPHG_03360 4.5e-64 ydjM M Lytic transglycolase
NIPEHPHG_03361 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
NIPEHPHG_03362 2.7e-258 iolT EGP Major facilitator Superfamily
NIPEHPHG_03363 4.7e-196 S Ion transport 2 domain protein
NIPEHPHG_03364 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
NIPEHPHG_03365 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
NIPEHPHG_03366 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NIPEHPHG_03367 5.1e-114 pspA KT Phage shock protein A
NIPEHPHG_03368 1.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
NIPEHPHG_03369 7.1e-256 gutA G MFS/sugar transport protein
NIPEHPHG_03370 3.8e-201 gutB 1.1.1.14 E Dehydrogenase
NIPEHPHG_03371 0.0 K NB-ARC domain
NIPEHPHG_03372 1.1e-08 ydjC S Abhydrolase domain containing 18
NIPEHPHG_03373 4.9e-257 J LlaJI restriction endonuclease
NIPEHPHG_03374 1.2e-199 V AAA domain (dynein-related subfamily)
NIPEHPHG_03376 1.6e-232 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
NIPEHPHG_03377 1.1e-250 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
NIPEHPHG_03378 6.4e-66 KL Phage plasmid primase P4 family
NIPEHPHG_03380 1.2e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NIPEHPHG_03381 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NIPEHPHG_03382 7.9e-129 ydiL S CAAX protease self-immunity
NIPEHPHG_03383 2.9e-27 ydiK S Domain of unknown function (DUF4305)
NIPEHPHG_03384 8.4e-126 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NIPEHPHG_03385 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NIPEHPHG_03386 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NIPEHPHG_03387 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NIPEHPHG_03388 0.0 ydiF S ABC transporter
NIPEHPHG_03389 3.6e-188 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NIPEHPHG_03390 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NIPEHPHG_03391 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
NIPEHPHG_03392 9.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
NIPEHPHG_03393 4.6e-185 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NIPEHPHG_03395 7.8e-08
NIPEHPHG_03396 7.2e-250 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIPEHPHG_03397 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
NIPEHPHG_03398 5.7e-140 srfAD Q thioesterase
NIPEHPHG_03399 4.2e-228 EGP Major Facilitator Superfamily
NIPEHPHG_03400 4.9e-91 S YcxB-like protein
NIPEHPHG_03401 7.4e-164 ycxC EG EamA-like transporter family
NIPEHPHG_03402 4.4e-255 ycxD K GntR family transcriptional regulator
NIPEHPHG_03403 5.5e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
NIPEHPHG_03404 4.4e-115 yczE S membrane
NIPEHPHG_03405 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NIPEHPHG_03406 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
NIPEHPHG_03407 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NIPEHPHG_03408 4.9e-162 bsdA K LysR substrate binding domain
NIPEHPHG_03409 2e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NIPEHPHG_03410 1.8e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NIPEHPHG_03411 4e-39 bsdD 4.1.1.61 S response to toxic substance
NIPEHPHG_03412 1.1e-83 yclD
NIPEHPHG_03413 6.2e-162 yclE 3.4.11.5 S Alpha beta hydrolase
NIPEHPHG_03414 1.5e-267 dtpT E amino acid peptide transporter
NIPEHPHG_03415 2.9e-310 yclG M Pectate lyase superfamily protein
NIPEHPHG_03417 6.8e-282 gerKA EG Spore germination protein
NIPEHPHG_03418 1.3e-232 gerKC S spore germination
NIPEHPHG_03419 9.9e-200 gerKB F Spore germination protein
NIPEHPHG_03420 3.9e-122 yclH P ABC transporter
NIPEHPHG_03421 1.7e-204 yclI V ABC transporter (permease) YclI
NIPEHPHG_03422 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NIPEHPHG_03423 1.8e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NIPEHPHG_03424 5.2e-71 S aspartate phosphatase
NIPEHPHG_03428 7.5e-242 lysC 2.7.2.4 E Belongs to the aspartokinase family
NIPEHPHG_03429 1.6e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIPEHPHG_03430 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIPEHPHG_03431 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
NIPEHPHG_03432 5.5e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
NIPEHPHG_03433 1.4e-251 ycnB EGP Major facilitator Superfamily
NIPEHPHG_03434 6.5e-154 ycnC K Transcriptional regulator
NIPEHPHG_03435 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
NIPEHPHG_03436 1.6e-45 ycnE S Monooxygenase
NIPEHPHG_03437 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
NIPEHPHG_03438 1.3e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NIPEHPHG_03439 4.4e-247 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NIPEHPHG_03440 3.4e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NIPEHPHG_03441 6.1e-149 glcU U Glucose uptake
NIPEHPHG_03442 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NIPEHPHG_03443 1.3e-100 ycnI S protein conserved in bacteria
NIPEHPHG_03444 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
NIPEHPHG_03445 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
NIPEHPHG_03446 7.3e-56
NIPEHPHG_03447 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
NIPEHPHG_03448 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NIPEHPHG_03449 7.3e-211 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
NIPEHPHG_03450 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
NIPEHPHG_03451 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NIPEHPHG_03452 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NIPEHPHG_03453 5e-113 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
NIPEHPHG_03454 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
NIPEHPHG_03456 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NIPEHPHG_03457 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
NIPEHPHG_03458 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
NIPEHPHG_03459 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
NIPEHPHG_03460 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
NIPEHPHG_03461 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
NIPEHPHG_03462 1.2e-132 kipR K Transcriptional regulator
NIPEHPHG_03463 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
NIPEHPHG_03465 1.4e-49 yczJ S biosynthesis
NIPEHPHG_03466 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
NIPEHPHG_03467 2.8e-176 ydhF S Oxidoreductase
NIPEHPHG_03468 0.0 mtlR K transcriptional regulator, MtlR
NIPEHPHG_03469 1.4e-294 ydaB IQ acyl-CoA ligase
NIPEHPHG_03470 1.1e-99 ydaC Q Methyltransferase domain
NIPEHPHG_03471 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NIPEHPHG_03472 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
NIPEHPHG_03473 5e-104 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NIPEHPHG_03474 6.8e-77 ydaG 1.4.3.5 S general stress protein
NIPEHPHG_03475 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NIPEHPHG_03476 5.1e-47 ydzA EGP Major facilitator Superfamily
NIPEHPHG_03477 2.5e-74 lrpC K Transcriptional regulator
NIPEHPHG_03478 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NIPEHPHG_03479 1.9e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
NIPEHPHG_03480 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
NIPEHPHG_03481 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
NIPEHPHG_03482 4.5e-233 ydaM M Glycosyl transferase family group 2
NIPEHPHG_03483 0.0 ydaN S Bacterial cellulose synthase subunit
NIPEHPHG_03484 0.0 ydaO E amino acid
NIPEHPHG_03485 4.6e-79 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NIPEHPHG_03486 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NIPEHPHG_03487 9.4e-40
NIPEHPHG_03488 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
NIPEHPHG_03490 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
NIPEHPHG_03491 3.8e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
NIPEHPHG_03493 8.9e-59 ydbB G Cupin domain
NIPEHPHG_03494 2.8e-63 ydbC S Domain of unknown function (DUF4937
NIPEHPHG_03495 3.2e-155 ydbD P Catalase
NIPEHPHG_03496 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NIPEHPHG_03497 2.5e-297 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NIPEHPHG_03498 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
NIPEHPHG_03499 6.3e-227 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NIPEHPHG_03500 4.4e-181 ydbI S AI-2E family transporter
NIPEHPHG_03501 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
NIPEHPHG_03502 5.5e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NIPEHPHG_03503 2.7e-52 ydbL
NIPEHPHG_03504 3e-220 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
NIPEHPHG_03505 1.1e-18 S Fur-regulated basic protein B
NIPEHPHG_03506 2.2e-07 S Fur-regulated basic protein A
NIPEHPHG_03507 1.9e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NIPEHPHG_03508 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NIPEHPHG_03509 4.6e-202 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NIPEHPHG_03510 1.9e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NIPEHPHG_03511 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NIPEHPHG_03512 2.1e-82 ydbS S Bacterial PH domain
NIPEHPHG_03513 2.2e-263 ydbT S Membrane
NIPEHPHG_03514 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
NIPEHPHG_03515 2.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NIPEHPHG_03516 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
NIPEHPHG_03517 2.3e-223 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NIPEHPHG_03518 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NIPEHPHG_03519 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
NIPEHPHG_03520 1.3e-143 rsbR T Positive regulator of sigma-B
NIPEHPHG_03521 5.2e-57 rsbS T antagonist
NIPEHPHG_03522 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NIPEHPHG_03523 7.1e-189 rsbU 3.1.3.3 KT phosphatase
NIPEHPHG_03524 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
NIPEHPHG_03525 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NIPEHPHG_03526 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NIPEHPHG_03527 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
NIPEHPHG_03531 1.5e-82 ydcG S EVE domain
NIPEHPHG_03532 1.6e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
NIPEHPHG_03533 0.0 yhgF K COG2183 Transcriptional accessory protein
NIPEHPHG_03534 1.6e-84 ydcK S Belongs to the SprT family
NIPEHPHG_03542 2.7e-188 luxA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NIPEHPHG_03543 2.4e-71 lrpA K transcriptional
NIPEHPHG_03544 1.5e-77 lrpB K transcriptional
NIPEHPHG_03545 9.6e-100 yddQ 3.5.1.19 Q Isochorismatase family
NIPEHPHG_03546 1.5e-143 yddR S Zn-dependent hydrolases of the beta-lactamase fold
NIPEHPHG_03547 5e-227 ydeG EGP Major facilitator Superfamily
NIPEHPHG_03552 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
NIPEHPHG_03553 8.7e-30 cspL K Cold shock
NIPEHPHG_03554 6.1e-79 carD K Transcription factor
NIPEHPHG_03555 4.6e-35 ydzE EG spore germination
NIPEHPHG_03556 1.1e-166 rhaS5 K AraC-like ligand binding domain
NIPEHPHG_03557 2.3e-173 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NIPEHPHG_03558 2.5e-166 ydeE K AraC family transcriptional regulator
NIPEHPHG_03559 2.2e-265 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NIPEHPHG_03560 3.4e-220 ydeG EGP Major facilitator superfamily
NIPEHPHG_03561 2.9e-47 ydeH
NIPEHPHG_03562 8.9e-107 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
NIPEHPHG_03563 4e-116
NIPEHPHG_03564 1.8e-153 ydeK EG -transporter
NIPEHPHG_03565 1.5e-274 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NIPEHPHG_03566 4.2e-74 maoC I N-terminal half of MaoC dehydratase
NIPEHPHG_03567 8.6e-107 ydeN S Serine hydrolase
NIPEHPHG_03568 1.1e-58 K HxlR-like helix-turn-helix
NIPEHPHG_03569 1.9e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NIPEHPHG_03570 4.8e-69 ydeP K Transcriptional regulator
NIPEHPHG_03571 1.6e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
NIPEHPHG_03572 1.2e-195 ydeR EGP Major facilitator Superfamily
NIPEHPHG_03573 8.4e-105 ydeS K Transcriptional regulator
NIPEHPHG_03574 1.3e-57 arsR K transcriptional
NIPEHPHG_03575 5.2e-232 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NIPEHPHG_03576 7.2e-149 ydfB J GNAT acetyltransferase
NIPEHPHG_03577 1e-162 ydfC EG EamA-like transporter family
NIPEHPHG_03578 1.9e-275 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NIPEHPHG_03579 5.9e-117 ydfE S Flavin reductase like domain
NIPEHPHG_03580 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
NIPEHPHG_03581 1.5e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NIPEHPHG_03583 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
NIPEHPHG_03584 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NIPEHPHG_03585 0.0 ydfJ S drug exporters of the RND superfamily
NIPEHPHG_03586 1.9e-177 S Alpha/beta hydrolase family
NIPEHPHG_03587 5.9e-118 S Protein of unknown function (DUF554)
NIPEHPHG_03588 3.2e-147 K Bacterial transcription activator, effector binding domain
NIPEHPHG_03589 1.6e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NIPEHPHG_03590 9.6e-112 ydfN C nitroreductase
NIPEHPHG_03591 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
NIPEHPHG_03592 8.8e-63 mhqP S DoxX
NIPEHPHG_03593 1.3e-57 traF CO Thioredoxin
NIPEHPHG_03594 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
NIPEHPHG_03595 6.3e-29
NIPEHPHG_03597 4.4e-118 ydfR S Protein of unknown function (DUF421)
NIPEHPHG_03598 5.2e-122 ydfS S Protein of unknown function (DUF421)
NIPEHPHG_03599 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
NIPEHPHG_03600 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
NIPEHPHG_03601 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
NIPEHPHG_03602 1.5e-101 K Bacterial regulatory proteins, tetR family
NIPEHPHG_03603 7.3e-53 S DoxX-like family
NIPEHPHG_03604 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
NIPEHPHG_03605 4.2e-308 expZ S ABC transporter
NIPEHPHG_03606 4e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NIPEHPHG_03607 4.6e-91 dinB S DinB family
NIPEHPHG_03608 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
NIPEHPHG_03609 0.0 ydgH S drug exporters of the RND superfamily
NIPEHPHG_03610 1e-113 drgA C nitroreductase
NIPEHPHG_03611 1.1e-69 ydgJ K Winged helix DNA-binding domain
NIPEHPHG_03612 2.5e-209 tcaB EGP Major facilitator Superfamily
NIPEHPHG_03613 1.2e-121 ydhB S membrane transporter protein
NIPEHPHG_03614 6.5e-122 ydhC K FCD
NIPEHPHG_03615 3.3e-244 ydhD M Glycosyl hydrolase
NIPEHPHG_03616 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NIPEHPHG_03617 1.9e-127
NIPEHPHG_03618 1.4e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NIPEHPHG_03619 4.6e-69 frataxin S Domain of unknown function (DU1801)
NIPEHPHG_03621 4.1e-86 K Acetyltransferase (GNAT) domain
NIPEHPHG_03622 1.8e-184 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NIPEHPHG_03623 1.7e-99 ydhK M Protein of unknown function (DUF1541)
NIPEHPHG_03624 4.6e-200 pbuE EGP Major facilitator Superfamily
NIPEHPHG_03625 1.1e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
NIPEHPHG_03626 3.5e-52 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
NIPEHPHG_03627 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIPEHPHG_03628 2.4e-288 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NIPEHPHG_03629 3.9e-133 ydhQ K UTRA
NIPEHPHG_03630 9.2e-172 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
NIPEHPHG_03631 4.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
NIPEHPHG_03632 7.3e-216 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
NIPEHPHG_03633 8.7e-78 ydhU P Catalase
NIPEHPHG_03634 1.1e-16 ydhU P Manganese containing catalase
NIPEHPHG_03637 1.3e-63 hxlR K transcriptional
NIPEHPHG_03638 3.3e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
NIPEHPHG_03639 4.6e-97 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
NIPEHPHG_03640 3e-187 tlpC 2.7.13.3 NT chemotaxis protein
NIPEHPHG_03641 3.2e-72 nucA M Deoxyribonuclease NucA/NucB
NIPEHPHG_03642 3.4e-70 nin S Competence protein J (ComJ)
NIPEHPHG_03643 1.2e-298 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NIPEHPHG_03644 3.5e-52 yckD S Protein of unknown function (DUF2680)
NIPEHPHG_03645 3.3e-77 yckC S membrane
NIPEHPHG_03648 1.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
NIPEHPHG_03649 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
NIPEHPHG_03650 1.4e-228 yciC S GTPases (G3E family)
NIPEHPHG_03651 5.5e-109 yciB M ErfK YbiS YcfS YnhG
NIPEHPHG_03652 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
NIPEHPHG_03653 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
NIPEHPHG_03654 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
NIPEHPHG_03655 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NIPEHPHG_03656 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NIPEHPHG_03657 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
NIPEHPHG_03658 9.3e-283 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NIPEHPHG_03659 1.3e-193 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NIPEHPHG_03660 5.7e-163 I alpha/beta hydrolase fold
NIPEHPHG_03661 1.2e-139 ycgR S permeases
NIPEHPHG_03662 2.6e-147 ycgQ S membrane
NIPEHPHG_03663 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
NIPEHPHG_03664 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NIPEHPHG_03665 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NIPEHPHG_03666 5.1e-170 ycgM E Proline dehydrogenase
NIPEHPHG_03667 2.9e-145 ycgL S Predicted nucleotidyltransferase
NIPEHPHG_03668 2.9e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
NIPEHPHG_03669 2.2e-179 oxyR3 K LysR substrate binding domain
NIPEHPHG_03670 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
NIPEHPHG_03671 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NIPEHPHG_03672 2.5e-109 tmrB S AAA domain
NIPEHPHG_03673 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NIPEHPHG_03674 2.4e-112 ycgI S Domain of unknown function (DUF1989)
NIPEHPHG_03675 5.6e-250 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
NIPEHPHG_03676 1.2e-151 yqcI S YqcI/YcgG family
NIPEHPHG_03677 6.8e-113 ycgF E Lysine exporter protein LysE YggA
NIPEHPHG_03678 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
NIPEHPHG_03679 6.2e-269 mdr EGP Major facilitator Superfamily
NIPEHPHG_03680 6.5e-293 lctP C L-lactate permease
NIPEHPHG_03681 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NIPEHPHG_03682 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
NIPEHPHG_03683 1.1e-98 ycgB
NIPEHPHG_03684 8.7e-257 ycgA S Membrane
NIPEHPHG_03685 1.2e-219 amhX S amidohydrolase
NIPEHPHG_03686 5.3e-164 opuAC E glycine betaine
NIPEHPHG_03687 1.3e-127 opuAB P glycine betaine
NIPEHPHG_03688 5.1e-229 proV 3.6.3.32 E glycine betaine
NIPEHPHG_03689 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
NIPEHPHG_03690 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
NIPEHPHG_03691 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
NIPEHPHG_03692 2e-192 yceH P Belongs to the TelA family
NIPEHPHG_03693 0.0 yceG S Putative component of 'biosynthetic module'
NIPEHPHG_03694 6.3e-137 terC P Protein of unknown function (DUF475)
NIPEHPHG_03695 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
NIPEHPHG_03696 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
NIPEHPHG_03697 3.9e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
NIPEHPHG_03698 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NIPEHPHG_03699 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NIPEHPHG_03700 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NIPEHPHG_03701 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
NIPEHPHG_03702 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
NIPEHPHG_03703 1.6e-140 IQ Enoyl-(Acyl carrier protein) reductase
NIPEHPHG_03704 5.5e-174 S response regulator aspartate phosphatase
NIPEHPHG_03705 1.7e-95 cwlK M D-alanyl-D-alanine carboxypeptidase
NIPEHPHG_03706 6.7e-268 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
NIPEHPHG_03707 5.9e-282 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
NIPEHPHG_03708 6.6e-177 ycdA S Domain of unknown function (DUF5105)
NIPEHPHG_03709 1.6e-174 yccK C Aldo keto reductase
NIPEHPHG_03710 4.5e-203 natB CP ABC-2 family transporter protein
NIPEHPHG_03711 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
NIPEHPHG_03712 1.2e-126 lytR_2 T LytTr DNA-binding domain
NIPEHPHG_03713 2e-161 2.7.13.3 T GHKL domain
NIPEHPHG_03714 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
NIPEHPHG_03715 2e-59 S RDD family
NIPEHPHG_03716 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NIPEHPHG_03717 2.2e-202 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NIPEHPHG_03718 4.8e-102 yxaF K Transcriptional regulator
NIPEHPHG_03719 5.8e-229 lmrB EGP the major facilitator superfamily
NIPEHPHG_03720 6.2e-210 ycbU E Selenocysteine lyase
NIPEHPHG_03721 1.4e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NIPEHPHG_03722 1.2e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NIPEHPHG_03723 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NIPEHPHG_03724 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
NIPEHPHG_03725 6.6e-136 ycbR T vWA found in TerF C terminus
NIPEHPHG_03726 1.3e-78 sleB 3.5.1.28 M Cell wall
NIPEHPHG_03727 8.2e-53 ycbP S Protein of unknown function (DUF2512)
NIPEHPHG_03728 2.1e-115 S ABC-2 family transporter protein
NIPEHPHG_03729 4.8e-168 ycbN V ABC transporter, ATP-binding protein
NIPEHPHG_03730 2.4e-170 T PhoQ Sensor
NIPEHPHG_03731 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NIPEHPHG_03732 7.3e-172 eamA1 EG spore germination
NIPEHPHG_03733 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
NIPEHPHG_03734 1.8e-178 ycbJ S Macrolide 2'-phosphotransferase
NIPEHPHG_03735 3.7e-298 garD 4.2.1.42, 4.2.1.7 G Altronate
NIPEHPHG_03736 1.5e-124 ycbG K FCD
NIPEHPHG_03737 2.2e-270 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NIPEHPHG_03738 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
NIPEHPHG_03739 3.7e-274 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NIPEHPHG_03740 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
NIPEHPHG_03741 9e-170 glnL T Regulator
NIPEHPHG_03742 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
NIPEHPHG_03743 1.5e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
NIPEHPHG_03744 2.3e-257 agcS E Sodium alanine symporter
NIPEHPHG_03745 9.3e-183 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
NIPEHPHG_03746 6.7e-262 mmuP E amino acid
NIPEHPHG_03747 5.4e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NIPEHPHG_03749 4.9e-128 K UTRA
NIPEHPHG_03750 2.1e-137 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NIPEHPHG_03751 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NIPEHPHG_03752 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NIPEHPHG_03753 3.9e-192 yceA S Belongs to the UPF0176 family
NIPEHPHG_03754 6.7e-167 ybfP K Transcriptional regulator
NIPEHPHG_03755 4.3e-258 S Erythromycin esterase
NIPEHPHG_03756 3.2e-46 ybfN
NIPEHPHG_03757 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NIPEHPHG_03758 2.7e-85 ybfM S SNARE associated Golgi protein
NIPEHPHG_03759 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NIPEHPHG_03760 2.5e-169 S Alpha/beta hydrolase family
NIPEHPHG_03762 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
NIPEHPHG_03763 1.9e-214 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NIPEHPHG_03764 2.3e-145 msmR K AraC-like ligand binding domain
NIPEHPHG_03765 8.8e-162 ybfH EG EamA-like transporter family
NIPEHPHG_03766 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
NIPEHPHG_03768 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
NIPEHPHG_03769 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
NIPEHPHG_03770 2.9e-35 S Protein of unknown function (DUF2651)
NIPEHPHG_03771 7.3e-258 glpT G -transporter
NIPEHPHG_03772 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NIPEHPHG_03773 2.3e-290 ybeC E amino acid
NIPEHPHG_03774 4.9e-41 ybyB
NIPEHPHG_03775 1.4e-247 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
NIPEHPHG_03776 7.2e-152 ybxI 3.5.2.6 V beta-lactamase
NIPEHPHG_03777 4.9e-30 ybxH S Family of unknown function (DUF5370)
NIPEHPHG_03778 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
NIPEHPHG_03779 2.4e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
NIPEHPHG_03780 1.5e-217 ybdO S Domain of unknown function (DUF4885)
NIPEHPHG_03781 4.8e-154 ybdN
NIPEHPHG_03782 1.6e-140 KLT Protein tyrosine kinase
NIPEHPHG_03784 1.8e-173 T His Kinase A (phospho-acceptor) domain
NIPEHPHG_03785 1.5e-123 T Transcriptional regulatory protein, C terminal
NIPEHPHG_03786 6.2e-182 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NIPEHPHG_03787 9.6e-79 txn CO Thioredoxin-like
NIPEHPHG_03788 7.8e-91 C HEAT repeats
NIPEHPHG_03789 4e-248 skfF S ABC transporter
NIPEHPHG_03790 1.9e-135 skfE V ABC transporter
NIPEHPHG_03791 1.6e-277 V CAAX protease self-immunity
NIPEHPHG_03792 9.1e-239 J 4Fe-4S single cluster domain
NIPEHPHG_03794 2e-203 ybcL EGP Major facilitator Superfamily
NIPEHPHG_03795 5.1e-50 ybzH K Helix-turn-helix domain
NIPEHPHG_03796 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
NIPEHPHG_03797 3.9e-47
NIPEHPHG_03798 3.7e-96 can 4.2.1.1 P carbonic anhydrase
NIPEHPHG_03799 0.0 ybcC S Belongs to the UPF0753 family
NIPEHPHG_03800 1.5e-278 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NIPEHPHG_03801 5.1e-101 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NIPEHPHG_03802 1.4e-121 adaA 3.2.2.21 K Transcriptional regulator
NIPEHPHG_03803 2.1e-176 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NIPEHPHG_03804 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NIPEHPHG_03805 9.3e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NIPEHPHG_03806 3e-225 ybbR S protein conserved in bacteria
NIPEHPHG_03807 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NIPEHPHG_03808 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NIPEHPHG_03809 8.5e-99 sigW K Belongs to the sigma-70 factor family. ECF subfamily
NIPEHPHG_03815 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
NIPEHPHG_03816 6.4e-87 ybbJ J acetyltransferase
NIPEHPHG_03817 2.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NIPEHPHG_03818 1.1e-150 ybbH K transcriptional
NIPEHPHG_03819 9.8e-234 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NIPEHPHG_03820 4e-256 yfeW 3.4.16.4 V Belongs to the UPF0214 family
NIPEHPHG_03821 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
NIPEHPHG_03822 4.4e-241 ybbC 3.2.1.52 S protein conserved in bacteria
NIPEHPHG_03823 5.4e-308 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
NIPEHPHG_03824 7.2e-167 feuA P Iron-uptake system-binding protein
NIPEHPHG_03825 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIPEHPHG_03826 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIPEHPHG_03827 2.2e-142 ybbA S Putative esterase
NIPEHPHG_03828 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
NIPEHPHG_03830 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
NIPEHPHG_03831 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NIPEHPHG_03832 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NIPEHPHG_03833 1.8e-37 yaaB S Domain of unknown function (DUF370)
NIPEHPHG_03834 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NIPEHPHG_03835 2.4e-33 yaaA S S4 domain
NIPEHPHG_03836 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NIPEHPHG_03837 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NIPEHPHG_03838 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NIPEHPHG_03839 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NIPEHPHG_03840 6.5e-108 jag S single-stranded nucleic acid binding R3H
NIPEHPHG_03841 3.7e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NIPEHPHG_03842 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NIPEHPHG_03843 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NIPEHPHG_03844 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NIPEHPHG_03845 1.9e-74 S Bacterial PH domain
NIPEHPHG_03846 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
NIPEHPHG_03847 2.1e-149 spo0J K Belongs to the ParB family
NIPEHPHG_03848 1.6e-111 yyaC S Sporulation protein YyaC
NIPEHPHG_03849 8.1e-177 yyaD S Membrane
NIPEHPHG_03850 2.3e-33 yyzM S protein conserved in bacteria
NIPEHPHG_03851 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NIPEHPHG_03852 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NIPEHPHG_03853 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
NIPEHPHG_03854 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NIPEHPHG_03855 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NIPEHPHG_03856 8.1e-145 xth 3.1.11.2 L exodeoxyribonuclease III
NIPEHPHG_03857 3.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
NIPEHPHG_03858 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NIPEHPHG_03859 5.1e-96 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
NIPEHPHG_03860 3.8e-246 EGP Major facilitator superfamily
NIPEHPHG_03861 9.5e-169 yyaK S CAAX protease self-immunity
NIPEHPHG_03862 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
NIPEHPHG_03863 3.3e-161 yyaM EG EamA-like transporter family
NIPEHPHG_03864 5.1e-61 yyaN K MerR HTH family regulatory protein
NIPEHPHG_03865 9.7e-44 yyaL O Highly conserved protein containing a thioredoxin domain
NIPEHPHG_03866 1.7e-249 tetL EGP Major facilitator Superfamily
NIPEHPHG_03867 1.7e-107 yyaP 1.5.1.3 H RibD C-terminal domain
NIPEHPHG_03868 5.4e-67 yyaQ S YjbR
NIPEHPHG_03869 5.4e-100 yyaR K Acetyltransferase (GNAT) domain
NIPEHPHG_03870 1.5e-101 yyaS S Membrane
NIPEHPHG_03871 5.9e-79 yjcF S Acetyltransferase (GNAT) domain
NIPEHPHG_03872 5.6e-77 yybA 2.3.1.57 K transcriptional
NIPEHPHG_03873 3e-127 S Metallo-beta-lactamase superfamily
NIPEHPHG_03874 2.7e-77 yybC
NIPEHPHG_03875 2e-79 yjcF S Acetyltransferase (GNAT) domain
NIPEHPHG_03876 2.1e-165 yybE K Transcriptional regulator
NIPEHPHG_03877 3.2e-220 ynfM EGP Major facilitator Superfamily
NIPEHPHG_03878 3e-124 yybG S Pentapeptide repeat-containing protein
NIPEHPHG_03879 5.9e-67 yybH S SnoaL-like domain
NIPEHPHG_03880 6.2e-132
NIPEHPHG_03881 2.6e-115 V ATPases associated with a variety of cellular activities
NIPEHPHG_03882 2e-127 S Protein of unknown function (DUF2705)
NIPEHPHG_03883 9e-122
NIPEHPHG_03884 4.1e-125
NIPEHPHG_03885 1.3e-78 yybN S Protein of unknown function (DUF2712)
NIPEHPHG_03886 1e-16
NIPEHPHG_03887 2.3e-240 yybO G COG0477 Permeases of the major facilitator superfamily
NIPEHPHG_03889 1.3e-70
NIPEHPHG_03890 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
NIPEHPHG_03891 1.4e-68 ydeP3 K Transcriptional regulator
NIPEHPHG_03892 3.9e-84 cotF M Spore coat protein
NIPEHPHG_03894 2.9e-160 yybS S membrane
NIPEHPHG_03895 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NIPEHPHG_03896 2.2e-73 rplI J binds to the 23S rRNA
NIPEHPHG_03897 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NIPEHPHG_03898 8.4e-221 yeaN P COG2807 Cyanate permease
NIPEHPHG_03899 1.9e-15 yycC K YycC-like protein
NIPEHPHG_03901 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
NIPEHPHG_03902 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NIPEHPHG_03903 8e-78 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NIPEHPHG_03904 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NIPEHPHG_03909 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NIPEHPHG_03910 0.0 vicK 2.7.13.3 T Histidine kinase
NIPEHPHG_03911 3.6e-260 yycH S protein conserved in bacteria
NIPEHPHG_03912 7.3e-155 yycI S protein conserved in bacteria
NIPEHPHG_03913 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NIPEHPHG_03914 8.4e-221 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NIPEHPHG_03915 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NIPEHPHG_03916 1.7e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
NIPEHPHG_03917 9.7e-261 rocE E amino acid
NIPEHPHG_03918 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
NIPEHPHG_03920 5e-188 S aspartate phosphatase
NIPEHPHG_03921 3.1e-86 yycN 2.3.1.128 K Acetyltransferase
NIPEHPHG_03922 5.8e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NIPEHPHG_03923 1.6e-221 yycP
NIPEHPHG_03924 2.1e-33 yycQ S Protein of unknown function (DUF2651)
NIPEHPHG_03926 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NIPEHPHG_03927 4.2e-71
NIPEHPHG_03928 1.1e-09 S YyzF-like protein
NIPEHPHG_03929 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NIPEHPHG_03930 7.3e-280 S Calcineurin-like phosphoesterase
NIPEHPHG_03931 3.5e-65
NIPEHPHG_03932 0.0 S Uncharacterised protein conserved in bacteria (DUF2326)
NIPEHPHG_03933 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
NIPEHPHG_03934 8e-12
NIPEHPHG_03935 7.7e-185 S Radical SAM superfamily
NIPEHPHG_03936 8.4e-134 yydH O Peptidase M50
NIPEHPHG_03937 1.8e-110 prrC P ABC transporter
NIPEHPHG_03938 3.3e-119 S ABC-2 family transporter protein
NIPEHPHG_03939 7.6e-13
NIPEHPHG_03940 1.3e-128 yydK K Transcriptional regulator
NIPEHPHG_03941 2.3e-34 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
NIPEHPHG_03942 6.4e-292 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NIPEHPHG_03943 3.8e-287 ahpF O Alkyl hydroperoxide reductase
NIPEHPHG_03944 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
NIPEHPHG_03945 3.8e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NIPEHPHG_03946 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
NIPEHPHG_03947 4.6e-304 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
NIPEHPHG_03948 7.3e-127 gntR K transcriptional
NIPEHPHG_03949 7e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NIPEHPHG_03950 4.5e-58 yxaB GM Polysaccharide pyruvyl transferase
NIPEHPHG_03951 3.5e-91 yxaB GM Polysaccharide pyruvyl transferase
NIPEHPHG_03952 2.6e-118 yxaC M effector of murein hydrolase
NIPEHPHG_03953 5.2e-50 S LrgA family
NIPEHPHG_03954 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
NIPEHPHG_03955 2.3e-201 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NIPEHPHG_03956 7.1e-101 yxaF K Transcriptional regulator
NIPEHPHG_03957 1.5e-199 yxaG 1.13.11.24 S AraC-like ligand binding domain
NIPEHPHG_03958 1.4e-228 P Protein of unknown function (DUF418)
NIPEHPHG_03959 1.1e-75 yxaI S membrane protein domain
NIPEHPHG_03960 3.5e-65 S Family of unknown function (DUF5391)
NIPEHPHG_03961 6.8e-93 S PQQ-like domain
NIPEHPHG_03962 7.6e-214 yxaM U MFS_1 like family
NIPEHPHG_03963 0.0 asnB 6.3.5.4 E Asparagine synthase
NIPEHPHG_03964 1.1e-86 yxnB
NIPEHPHG_03965 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
NIPEHPHG_03966 3.3e-127 yxbB Q Met-10+ like-protein
NIPEHPHG_03967 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
NIPEHPHG_03968 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
NIPEHPHG_03969 1.2e-84 gerD
NIPEHPHG_03970 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NIPEHPHG_03971 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NIPEHPHG_03972 9.7e-66 ybaK S Protein of unknown function (DUF2521)
NIPEHPHG_03973 8.2e-145 ybaJ Q Methyltransferase domain
NIPEHPHG_03974 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
NIPEHPHG_03975 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NIPEHPHG_03976 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NIPEHPHG_03977 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NIPEHPHG_03978 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NIPEHPHG_03979 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NIPEHPHG_03980 3.6e-58 rplQ J Ribosomal protein L17
NIPEHPHG_03981 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIPEHPHG_03982 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NIPEHPHG_03983 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NIPEHPHG_03984 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NIPEHPHG_03985 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NIPEHPHG_03986 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
NIPEHPHG_03987 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NIPEHPHG_03988 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NIPEHPHG_03989 1.8e-72 rplO J binds to the 23S rRNA
NIPEHPHG_03990 1.9e-23 rpmD J Ribosomal protein L30
NIPEHPHG_03991 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NIPEHPHG_03992 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NIPEHPHG_03993 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NIPEHPHG_03994 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NIPEHPHG_03995 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NIPEHPHG_03996 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NIPEHPHG_03997 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NIPEHPHG_03998 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NIPEHPHG_03999 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NIPEHPHG_04000 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
NIPEHPHG_04001 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NIPEHPHG_04002 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NIPEHPHG_04003 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NIPEHPHG_04004 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NIPEHPHG_04005 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NIPEHPHG_04006 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NIPEHPHG_04007 3e-105 rplD J Forms part of the polypeptide exit tunnel
NIPEHPHG_04008 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NIPEHPHG_04009 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NIPEHPHG_04010 9.1e-186 ybaC 3.4.11.5 S Alpha/beta hydrolase family
NIPEHPHG_04011 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NIPEHPHG_04012 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NIPEHPHG_04013 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NIPEHPHG_04014 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NIPEHPHG_04015 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
NIPEHPHG_04016 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIPEHPHG_04017 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIPEHPHG_04018 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
NIPEHPHG_04019 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NIPEHPHG_04020 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NIPEHPHG_04021 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NIPEHPHG_04022 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NIPEHPHG_04023 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
NIPEHPHG_04024 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NIPEHPHG_04025 4.4e-115 sigH K Belongs to the sigma-70 factor family
NIPEHPHG_04026 1.2e-88 yacP S RNA-binding protein containing a PIN domain
NIPEHPHG_04027 1.2e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIPEHPHG_04028 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NIPEHPHG_04029 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NIPEHPHG_04030 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
NIPEHPHG_04031 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NIPEHPHG_04032 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NIPEHPHG_04033 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NIPEHPHG_04034 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
NIPEHPHG_04035 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NIPEHPHG_04036 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NIPEHPHG_04037 0.0 clpC O Belongs to the ClpA ClpB family
NIPEHPHG_04038 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NIPEHPHG_04039 4.7e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
NIPEHPHG_04040 2.9e-76 ctsR K Belongs to the CtsR family
NIPEHPHG_04041 3.4e-31 csfB S Inhibitor of sigma-G Gin
NIPEHPHG_04042 4.7e-103 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NIPEHPHG_04043 4.5e-203 yaaN P Belongs to the TelA family
NIPEHPHG_04044 1.1e-275 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
NIPEHPHG_04045 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NIPEHPHG_04046 2.2e-54 yaaQ S protein conserved in bacteria
NIPEHPHG_04047 1.5e-71 yaaR S protein conserved in bacteria
NIPEHPHG_04048 2.2e-182 holB 2.7.7.7 L DNA polymerase III
NIPEHPHG_04049 2.1e-146 yaaT S stage 0 sporulation protein
NIPEHPHG_04050 4.8e-31 yabA L Involved in initiation control of chromosome replication
NIPEHPHG_04051 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
NIPEHPHG_04052 1.5e-49 yazA L endonuclease containing a URI domain
NIPEHPHG_04053 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NIPEHPHG_04054 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
NIPEHPHG_04055 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NIPEHPHG_04056 1.8e-144 tatD L hydrolase, TatD
NIPEHPHG_04057 4.3e-194 rpfB GH23 T protein conserved in bacteria
NIPEHPHG_04058 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NIPEHPHG_04059 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NIPEHPHG_04060 1.6e-136 yabG S peptidase
NIPEHPHG_04061 7.8e-39 veg S protein conserved in bacteria
NIPEHPHG_04062 8.3e-27 sspF S DNA topological change
NIPEHPHG_04063 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NIPEHPHG_04064 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NIPEHPHG_04065 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
NIPEHPHG_04066 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NIPEHPHG_04067 6.6e-230 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NIPEHPHG_04068 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NIPEHPHG_04069 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NIPEHPHG_04070 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NIPEHPHG_04071 2.4e-39 yabK S Peptide ABC transporter permease
NIPEHPHG_04072 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NIPEHPHG_04073 1.5e-92 spoVT K stage V sporulation protein
NIPEHPHG_04074 2.4e-287 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NIPEHPHG_04075 2.7e-245 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NIPEHPHG_04076 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NIPEHPHG_04077 1.5e-49 yabP S Sporulation protein YabP
NIPEHPHG_04078 3.9e-108 yabQ S spore cortex biosynthesis protein
NIPEHPHG_04079 1.1e-44 divIC D Septum formation initiator
NIPEHPHG_04080 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
NIPEHPHG_04083 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
NIPEHPHG_04084 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
NIPEHPHG_04085 6.7e-187 KLT serine threonine protein kinase
NIPEHPHG_04086 3.5e-274 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NIPEHPHG_04087 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NIPEHPHG_04088 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NIPEHPHG_04089 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NIPEHPHG_04090 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NIPEHPHG_04091 3.1e-153 yacD 5.2.1.8 O peptidyl-prolyl isomerase
NIPEHPHG_04092 8.9e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NIPEHPHG_04093 4.7e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NIPEHPHG_04094 1.5e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
NIPEHPHG_04095 1.6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
NIPEHPHG_04096 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NIPEHPHG_04097 8.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NIPEHPHG_04098 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NIPEHPHG_04099 4.1e-30 yazB K transcriptional
NIPEHPHG_04100 3.7e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NIPEHPHG_04101 1.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NIPEHPHG_04102 2.7e-182 yaaC S YaaC-like Protein
NIPEHPHG_04103 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NIPEHPHG_04104 5.2e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NIPEHPHG_04105 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NIPEHPHG_04106 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NIPEHPHG_04107 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NIPEHPHG_04108 1.3e-09
NIPEHPHG_04109 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
NIPEHPHG_04110 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
NIPEHPHG_04111 5.6e-215 yaaH M Glycoside Hydrolase Family
NIPEHPHG_04112 2.4e-98 yaaI Q COG1335 Amidases related to nicotinamidase
NIPEHPHG_04113 1e-84 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NIPEHPHG_04114 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NIPEHPHG_04115 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NIPEHPHG_04116 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NIPEHPHG_04117 7.9e-32 yaaL S Protein of unknown function (DUF2508)
NIPEHPHG_04118 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
NIPEHPHG_04119 2.6e-53 3.2.1.17 M Lysin motif
NIPEHPHG_04121 1.9e-25
NIPEHPHG_04122 6.2e-07
NIPEHPHG_04123 5.8e-48 S amidase activity
NIPEHPHG_04130 3.4e-07 S integral to membrane
NIPEHPHG_04131 1.3e-119
NIPEHPHG_04134 1.1e-78 S ATPase activity, uncoupled
NIPEHPHG_04136 1.4e-18
NIPEHPHG_04138 3.1e-154 L DNA binding
NIPEHPHG_04141 2.5e-40 S Pfam:Phi29_Phage_SSB
NIPEHPHG_04144 6.7e-270 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIPEHPHG_04145 3.4e-39 S COG NOG14552 non supervised orthologous group
NIPEHPHG_04149 2e-08
NIPEHPHG_04156 2e-08
NIPEHPHG_04157 2.1e-55 cysA 3.6.3.25, 3.6.3.29 P Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NIPEHPHG_04158 9.6e-39 hemB 4.2.1.24 H Belongs to the ALAD family
NIPEHPHG_04159 2.2e-71 fecB P Pfam Periplasmic binding protein
NIPEHPHG_04162 1.7e-61 czcC MU Outer membrane efflux protein
NIPEHPHG_04163 2.4e-50 cheA 2.7.13.3 NT chemotaxis protein
NIPEHPHG_04164 1.4e-17 L Methyltransferase small domain
NIPEHPHG_04165 7.3e-33 phcS 2.7.13.3 T Histidine kinase
NIPEHPHG_04166 9.1e-47 oprM M RND efflux system, outer membrane lipoprotein, NodT family
NIPEHPHG_04167 2.5e-46 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
NIPEHPHG_04168 2.9e-22 L Domain of unknown function (DUF4942)
NIPEHPHG_04169 2.2e-37 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)