ORF_ID e_value Gene_name EC_number CAZy COGs Description
APMBIKAL_00005 2e-08
APMBIKAL_00012 1.3e-09
APMBIKAL_00013 7.8e-08
APMBIKAL_00022 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
APMBIKAL_00023 2.6e-195 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
APMBIKAL_00024 2.9e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
APMBIKAL_00025 2.7e-282 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
APMBIKAL_00026 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
APMBIKAL_00027 3.8e-76 tspO T membrane
APMBIKAL_00028 5.7e-205 cotI S Spore coat protein
APMBIKAL_00029 4.1e-217 cotSA M Glycosyl transferases group 1
APMBIKAL_00030 4.3e-205 cotS S Seems to be required for the assembly of the CotSA protein in spores
APMBIKAL_00032 3.6e-235 ytcC M Glycosyltransferase Family 4
APMBIKAL_00033 3.3e-180 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
APMBIKAL_00034 2.9e-243 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
APMBIKAL_00035 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
APMBIKAL_00036 4.4e-132 dksA T COG1734 DnaK suppressor protein
APMBIKAL_00037 2.5e-272 menF 5.4.4.2 HQ Isochorismate synthase
APMBIKAL_00038 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
APMBIKAL_00039 3.2e-155 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
APMBIKAL_00040 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
APMBIKAL_00041 2.2e-276 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
APMBIKAL_00042 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
APMBIKAL_00043 2e-169 troA P Belongs to the bacterial solute-binding protein 9 family
APMBIKAL_00044 2.1e-137 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
APMBIKAL_00045 1.1e-231 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
APMBIKAL_00046 8.3e-149 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
APMBIKAL_00047 1.1e-24 S Domain of Unknown Function (DUF1540)
APMBIKAL_00048 1.1e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
APMBIKAL_00049 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
APMBIKAL_00050 3.6e-41 rpmE2 J Ribosomal protein L31
APMBIKAL_00051 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
APMBIKAL_00052 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
APMBIKAL_00053 1.1e-72 ytkA S YtkA-like
APMBIKAL_00055 2.1e-76 dps P Belongs to the Dps family
APMBIKAL_00056 7.8e-62 ytkC S Bacteriophage holin family
APMBIKAL_00057 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
APMBIKAL_00058 1.2e-141 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
APMBIKAL_00059 1.4e-144 ytlC P ABC transporter
APMBIKAL_00060 2e-186 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
APMBIKAL_00061 2.7e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
APMBIKAL_00062 1.6e-38 ytmB S Protein of unknown function (DUF2584)
APMBIKAL_00063 8.8e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
APMBIKAL_00064 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
APMBIKAL_00065 0.0 asnB 6.3.5.4 E Asparagine synthase
APMBIKAL_00066 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
APMBIKAL_00067 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
APMBIKAL_00068 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
APMBIKAL_00069 1.8e-214 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
APMBIKAL_00070 7.4e-106 ytqB J Putative rRNA methylase
APMBIKAL_00071 4e-189 yhcC S Fe-S oxidoreductase
APMBIKAL_00072 6.7e-41 ytzC S Protein of unknown function (DUF2524)
APMBIKAL_00074 5.1e-66 ytrA K GntR family transcriptional regulator
APMBIKAL_00075 4.2e-161 ytrB P abc transporter atp-binding protein
APMBIKAL_00076 4.7e-161 P ABC-2 family transporter protein
APMBIKAL_00077 1.8e-149
APMBIKAL_00078 7e-127 ytrE V ABC transporter, ATP-binding protein
APMBIKAL_00079 1.6e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
APMBIKAL_00080 1.1e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APMBIKAL_00081 4e-184 T PhoQ Sensor
APMBIKAL_00082 1.1e-138 bceA V ABC transporter, ATP-binding protein
APMBIKAL_00083 0.0 bceB V ABC transporter (permease)
APMBIKAL_00084 1.3e-41 yttA 2.7.13.3 S Pfam Transposase IS66
APMBIKAL_00085 7.3e-209 yttB EGP Major facilitator Superfamily
APMBIKAL_00086 3.9e-142 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
APMBIKAL_00087 7.7e-55 ytvB S Protein of unknown function (DUF4257)
APMBIKAL_00088 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
APMBIKAL_00089 2.1e-51 ytwF P Sulfurtransferase
APMBIKAL_00090 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
APMBIKAL_00091 3.7e-143 amyC P ABC transporter (permease)
APMBIKAL_00092 1.4e-167 amyD P ABC transporter
APMBIKAL_00093 2.8e-246 msmE G Bacterial extracellular solute-binding protein
APMBIKAL_00094 4.3e-189 msmR K Transcriptional regulator
APMBIKAL_00095 4.1e-172 ytaP S Acetyl xylan esterase (AXE1)
APMBIKAL_00096 6.4e-139 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
APMBIKAL_00097 1.7e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
APMBIKAL_00098 2.5e-217 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
APMBIKAL_00099 3.5e-126 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
APMBIKAL_00100 8.4e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
APMBIKAL_00101 2.2e-221 bioI 1.14.14.46 C Cytochrome P450
APMBIKAL_00102 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
APMBIKAL_00103 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
APMBIKAL_00104 6.2e-290 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
APMBIKAL_00105 0.0 ytdP K Transcriptional regulator
APMBIKAL_00106 7.5e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
APMBIKAL_00107 1.6e-218 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
APMBIKAL_00108 1.3e-72 yteS G transport
APMBIKAL_00109 7.8e-257 yteT S Oxidoreductase family, C-terminal alpha/beta domain
APMBIKAL_00110 4.5e-115 yteU S Integral membrane protein
APMBIKAL_00111 3.1e-26 yteV S Sporulation protein Cse60
APMBIKAL_00112 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
APMBIKAL_00113 8.2e-232 ytfP S HI0933-like protein
APMBIKAL_00114 2.1e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APMBIKAL_00115 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
APMBIKAL_00116 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
APMBIKAL_00117 4.8e-131 ythP V ABC transporter
APMBIKAL_00118 2.4e-204 ythQ U Bacterial ABC transporter protein EcsB
APMBIKAL_00119 2.1e-225 pbuO S permease
APMBIKAL_00120 2.7e-271 pepV 3.5.1.18 E Dipeptidase
APMBIKAL_00121 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
APMBIKAL_00122 2.3e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
APMBIKAL_00123 2.5e-164 ytlQ
APMBIKAL_00124 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
APMBIKAL_00125 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
APMBIKAL_00126 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
APMBIKAL_00127 2e-45 ytzH S YtzH-like protein
APMBIKAL_00128 2e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
APMBIKAL_00129 6.4e-151 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
APMBIKAL_00130 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
APMBIKAL_00131 1.1e-50 ytzB S small secreted protein
APMBIKAL_00132 1.4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
APMBIKAL_00133 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
APMBIKAL_00134 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
APMBIKAL_00135 9.8e-149 ytpQ S Belongs to the UPF0354 family
APMBIKAL_00136 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
APMBIKAL_00137 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
APMBIKAL_00138 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
APMBIKAL_00139 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
APMBIKAL_00140 6.6e-17 ytxH S COG4980 Gas vesicle protein
APMBIKAL_00141 6.3e-54 ytxJ O Protein of unknown function (DUF2847)
APMBIKAL_00142 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
APMBIKAL_00143 1.7e-182 ccpA K catabolite control protein A
APMBIKAL_00144 6e-146 motA N flagellar motor
APMBIKAL_00145 2.3e-125 motS N Flagellar motor protein
APMBIKAL_00146 5.4e-225 acuC BQ histone deacetylase
APMBIKAL_00147 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
APMBIKAL_00148 1.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
APMBIKAL_00149 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
APMBIKAL_00150 1.8e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
APMBIKAL_00152 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
APMBIKAL_00153 1e-307 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
APMBIKAL_00154 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
APMBIKAL_00155 6.5e-108 yttP K Transcriptional regulator
APMBIKAL_00156 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
APMBIKAL_00157 9.2e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
APMBIKAL_00158 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
APMBIKAL_00159 5.6e-206 iscS2 2.8.1.7 E Cysteine desulfurase
APMBIKAL_00160 8.7e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
APMBIKAL_00161 2e-29 sspB S spore protein
APMBIKAL_00162 1e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
APMBIKAL_00163 0.0 ytcJ S amidohydrolase
APMBIKAL_00164 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
APMBIKAL_00165 1.6e-180 sppA OU signal peptide peptidase SppA
APMBIKAL_00166 1.5e-86 yteJ S RDD family
APMBIKAL_00167 5.6e-116 ytfI S Protein of unknown function (DUF2953)
APMBIKAL_00168 8.7e-70 ytfJ S Sporulation protein YtfJ
APMBIKAL_00169 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
APMBIKAL_00170 7e-165 ytxK 2.1.1.72 L DNA methylase
APMBIKAL_00171 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
APMBIKAL_00172 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
APMBIKAL_00173 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
APMBIKAL_00174 3.4e-266 argH 4.3.2.1 E argininosuccinate lyase
APMBIKAL_00176 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APMBIKAL_00177 1.7e-130 ytkL S Belongs to the UPF0173 family
APMBIKAL_00178 1.2e-171 ytlI K LysR substrate binding domain
APMBIKAL_00179 1.2e-99 ytmI K Acetyltransferase (GNAT) domain
APMBIKAL_00180 2.1e-151 tcyK ET Bacterial periplasmic substrate-binding proteins
APMBIKAL_00181 6.4e-148 tcyK M Bacterial periplasmic substrate-binding proteins
APMBIKAL_00182 1.4e-122 tcyL P Binding-protein-dependent transport system inner membrane component
APMBIKAL_00183 1.6e-118 tcyM U Binding-protein-dependent transport system inner membrane component
APMBIKAL_00184 3.9e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
APMBIKAL_00185 4.9e-182 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APMBIKAL_00186 2.1e-45 ytnI O COG0695 Glutaredoxin and related proteins
APMBIKAL_00187 2.6e-255 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APMBIKAL_00188 9e-127 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
APMBIKAL_00189 1e-237 ytnL 3.5.1.47 E hydrolase activity
APMBIKAL_00190 1.2e-158 ytnM S membrane transporter protein
APMBIKAL_00191 8e-241 ytoI K transcriptional regulator containing CBS domains
APMBIKAL_00192 2.4e-47 ytpI S YtpI-like protein
APMBIKAL_00193 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
APMBIKAL_00194 9.2e-29
APMBIKAL_00195 8.2e-69 ytrI
APMBIKAL_00196 3.2e-56 ytrH S Sporulation protein YtrH
APMBIKAL_00197 0.0 dnaE 2.7.7.7 L DNA polymerase
APMBIKAL_00198 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
APMBIKAL_00199 2.1e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
APMBIKAL_00200 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
APMBIKAL_00201 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
APMBIKAL_00202 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
APMBIKAL_00203 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
APMBIKAL_00204 2.6e-192 ytvI S sporulation integral membrane protein YtvI
APMBIKAL_00205 2.3e-70 yeaL S membrane
APMBIKAL_00206 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
APMBIKAL_00207 4.1e-242 icd 1.1.1.42 C isocitrate
APMBIKAL_00208 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
APMBIKAL_00209 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APMBIKAL_00210 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
APMBIKAL_00211 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
APMBIKAL_00212 7.8e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
APMBIKAL_00213 1.1e-107 ytaF P Probably functions as a manganese efflux pump
APMBIKAL_00214 3.8e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
APMBIKAL_00215 8.9e-161 ytbE S reductase
APMBIKAL_00216 2.5e-201 ytbD EGP Major facilitator Superfamily
APMBIKAL_00217 9.9e-67 ytcD K Transcriptional regulator
APMBIKAL_00218 3.7e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
APMBIKAL_00219 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
APMBIKAL_00220 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
APMBIKAL_00221 1.5e-264 dnaB L Membrane attachment protein
APMBIKAL_00222 3e-173 dnaI L Primosomal protein DnaI
APMBIKAL_00223 4.9e-111 ytxB S SNARE associated Golgi protein
APMBIKAL_00224 3.8e-159 ytxC S YtxC-like family
APMBIKAL_00226 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
APMBIKAL_00227 2.8e-148 ysaA S HAD-hyrolase-like
APMBIKAL_00228 0.0 lytS 2.7.13.3 T Histidine kinase
APMBIKAL_00229 7e-130 lytT T COG3279 Response regulator of the LytR AlgR family
APMBIKAL_00230 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
APMBIKAL_00231 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
APMBIKAL_00233 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
APMBIKAL_00234 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
APMBIKAL_00235 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
APMBIKAL_00236 7.5e-45 ysdA S Membrane
APMBIKAL_00237 3.5e-67 ysdB S Sigma-w pathway protein YsdB
APMBIKAL_00238 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
APMBIKAL_00239 1.2e-188 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
APMBIKAL_00240 1.5e-291 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
APMBIKAL_00241 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
APMBIKAL_00242 5.5e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
APMBIKAL_00243 6e-146 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
APMBIKAL_00244 1.8e-220 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
APMBIKAL_00245 3.1e-253 araN G carbohydrate transport
APMBIKAL_00246 4.2e-167 araP G carbohydrate transport
APMBIKAL_00247 3.8e-143 araQ G transport system permease
APMBIKAL_00248 2.5e-299 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
APMBIKAL_00249 0.0 cstA T Carbon starvation protein
APMBIKAL_00251 2.8e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
APMBIKAL_00252 1.5e-255 glcF C Glycolate oxidase
APMBIKAL_00253 8.8e-262 glcD 1.1.3.15 C Glycolate oxidase subunit
APMBIKAL_00254 4.4e-208 ysfB KT regulator
APMBIKAL_00255 5.8e-32 sspI S Belongs to the SspI family
APMBIKAL_00256 2.2e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APMBIKAL_00257 8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
APMBIKAL_00258 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
APMBIKAL_00259 2.4e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
APMBIKAL_00260 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
APMBIKAL_00261 1.3e-85 cvpA S membrane protein, required for colicin V production
APMBIKAL_00262 0.0 polX L COG1796 DNA polymerase IV (family X)
APMBIKAL_00263 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
APMBIKAL_00264 7.3e-68 yshE S membrane
APMBIKAL_00265 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
APMBIKAL_00266 2.7e-100 fadR K Transcriptional regulator
APMBIKAL_00267 7e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
APMBIKAL_00268 4.5e-135 etfB C Electron transfer flavoprotein
APMBIKAL_00269 2.7e-177 etfA C Electron transfer flavoprotein
APMBIKAL_00271 2.4e-302 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
APMBIKAL_00272 2e-52 trxA O Belongs to the thioredoxin family
APMBIKAL_00273 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
APMBIKAL_00274 6.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
APMBIKAL_00275 1.2e-79 yslB S Protein of unknown function (DUF2507)
APMBIKAL_00276 2.4e-107 sdhC C succinate dehydrogenase
APMBIKAL_00277 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
APMBIKAL_00278 1.7e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
APMBIKAL_00279 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
APMBIKAL_00280 3.3e-30 gerE K Transcriptional regulator
APMBIKAL_00281 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
APMBIKAL_00282 8.1e-151 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
APMBIKAL_00283 9.4e-195 gerM S COG5401 Spore germination protein
APMBIKAL_00284 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
APMBIKAL_00285 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
APMBIKAL_00286 5.3e-92 ysnB S Phosphoesterase
APMBIKAL_00288 1e-89 L Phage integrase family
APMBIKAL_00290 1.1e-39 S Helix-turn-helix domain
APMBIKAL_00291 4.6e-41
APMBIKAL_00294 1e-15
APMBIKAL_00295 1.2e-32
APMBIKAL_00297 4.8e-108 L DNA-dependent DNA replication
APMBIKAL_00301 3.7e-143 dnaG 3.6.4.12 L DnaB-like helicase C terminal domain
APMBIKAL_00302 8e-132 dnaG L Toprim-like
APMBIKAL_00303 2.9e-11 K Cro/C1-type HTH DNA-binding domain
APMBIKAL_00304 5.7e-08 S Cro/C1-type HTH DNA-binding domain
APMBIKAL_00305 2.4e-43
APMBIKAL_00308 1.5e-09
APMBIKAL_00310 2.8e-42
APMBIKAL_00311 6.3e-49
APMBIKAL_00313 7.1e-43
APMBIKAL_00314 7.3e-207 L 3'-5' exonuclease
APMBIKAL_00316 1.2e-154
APMBIKAL_00317 1e-19
APMBIKAL_00318 6.3e-30 ruvC 3.1.22.4 L Crossover junction endodeoxyribonuclease RuvC
APMBIKAL_00322 1e-36 nrdI 1.17.4.1 F Belongs to the NrdI family
APMBIKAL_00323 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APMBIKAL_00325 2.7e-153 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APMBIKAL_00326 8.5e-56 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F deoxyuridine 5'-triphosphate nucleotidohydrolase
APMBIKAL_00327 1.5e-27 S AP2 domain
APMBIKAL_00328 8e-99 thyX 2.1.1.148 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
APMBIKAL_00329 1.6e-34 S protein conserved in bacteria
APMBIKAL_00330 9.3e-70 S SprT-like family
APMBIKAL_00331 7.3e-32
APMBIKAL_00333 6.5e-70 2.7.1.24 H dephospho-CoA kinase activity
APMBIKAL_00335 8.1e-42 K Sigma-70, region 4
APMBIKAL_00336 1.7e-55
APMBIKAL_00337 5.6e-12
APMBIKAL_00338 6.2e-25 S Helix-turn-helix domain
APMBIKAL_00340 7.1e-123 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
APMBIKAL_00342 1.8e-21
APMBIKAL_00343 8.2e-49
APMBIKAL_00346 1.2e-119 3.2.1.15 M Right handed beta helix region
APMBIKAL_00347 5.1e-57 S Pfam:DUF867
APMBIKAL_00348 7.1e-33 K Cro/C1-type HTH DNA-binding domain
APMBIKAL_00349 7e-43 M Glycosyltransferase like family 2
APMBIKAL_00353 1.5e-15 S Phage Terminase
APMBIKAL_00356 2.2e-79
APMBIKAL_00358 2.6e-44 L Phage terminase, small subunit
APMBIKAL_00359 0.0 S Terminase
APMBIKAL_00360 3.9e-224 S Phage portal protein
APMBIKAL_00361 1.6e-121 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
APMBIKAL_00362 2.2e-165 S Phage capsid family
APMBIKAL_00363 1.4e-28 N domain, Protein
APMBIKAL_00364 5.9e-25 S Phage gp6-like head-tail connector protein
APMBIKAL_00365 6.4e-33 S Phage head-tail joining protein
APMBIKAL_00366 5.8e-07 S Bacteriophage HK97-gp10, putative tail-component
APMBIKAL_00367 2.2e-25
APMBIKAL_00368 2.3e-70 N phage major tail protein, phi13 family
APMBIKAL_00369 1.4e-16
APMBIKAL_00370 2.2e-111 D Phage tail tape measure protein
APMBIKAL_00371 1.5e-104 S Phage tail protein
APMBIKAL_00372 5.7e-182 L Prophage endopeptidase tail
APMBIKAL_00373 1.3e-43
APMBIKAL_00374 6.7e-157 S Domain of unknown function (DUF2479)
APMBIKAL_00375 2e-19
APMBIKAL_00377 8.8e-30 S Haemolysin XhlA
APMBIKAL_00378 3.8e-152 xlyB 3.5.1.28 CBM50 MT N-acetylmuramoyl-L-alanine amidase
APMBIKAL_00379 6.3e-33 S Bacteriophage A118-like holin, Hol118
APMBIKAL_00380 8.7e-08
APMBIKAL_00381 1.3e-17 S YolD-like protein
APMBIKAL_00382 1.1e-20 S protein disulfide oxidoreductase activity
APMBIKAL_00384 6.1e-128 ftsK D FtsK/SpoIIIE family
APMBIKAL_00385 3.4e-64
APMBIKAL_00386 1.3e-15 K Transcriptional regulator
APMBIKAL_00387 3.7e-98 K Helix-turn-helix domain
APMBIKAL_00388 2e-133 ysnF S protein conserved in bacteria
APMBIKAL_00389 1.6e-79 ysnE K acetyltransferase
APMBIKAL_00391 0.0 ilvB 2.2.1.6 E Acetolactate synthase
APMBIKAL_00392 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
APMBIKAL_00393 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
APMBIKAL_00394 3.8e-290 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
APMBIKAL_00395 5.7e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
APMBIKAL_00396 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
APMBIKAL_00397 9e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
APMBIKAL_00398 2.5e-186 ysoA H Tetratricopeptide repeat
APMBIKAL_00399 1.8e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
APMBIKAL_00400 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
APMBIKAL_00401 9.2e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
APMBIKAL_00402 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
APMBIKAL_00403 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
APMBIKAL_00404 1.4e-89 ysxD
APMBIKAL_00405 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
APMBIKAL_00406 3.6e-146 hemX O cytochrome C
APMBIKAL_00407 8.7e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
APMBIKAL_00408 1.7e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
APMBIKAL_00409 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
APMBIKAL_00410 1.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
APMBIKAL_00411 5.6e-218 spoVID M stage VI sporulation protein D
APMBIKAL_00412 2.3e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
APMBIKAL_00413 1.6e-25
APMBIKAL_00414 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
APMBIKAL_00415 7.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
APMBIKAL_00416 1.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
APMBIKAL_00417 7.6e-167 spoIIB S Sporulation related domain
APMBIKAL_00418 8.3e-102 maf D septum formation protein Maf
APMBIKAL_00419 1.3e-125 radC E Belongs to the UPF0758 family
APMBIKAL_00420 1.8e-184 mreB D Rod shape-determining protein MreB
APMBIKAL_00421 2.8e-157 mreC M Involved in formation and maintenance of cell shape
APMBIKAL_00422 1.4e-84 mreD M shape-determining protein
APMBIKAL_00423 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
APMBIKAL_00424 4.7e-143 minD D Belongs to the ParA family
APMBIKAL_00425 4.2e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
APMBIKAL_00426 9.2e-161 spoIVFB S Stage IV sporulation protein
APMBIKAL_00427 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
APMBIKAL_00428 1e-54 ysxB J ribosomal protein
APMBIKAL_00429 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
APMBIKAL_00430 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
APMBIKAL_00431 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
APMBIKAL_00432 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
APMBIKAL_00433 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
APMBIKAL_00434 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
APMBIKAL_00435 1.6e-227 nifS 2.8.1.7 E Cysteine desulfurase
APMBIKAL_00436 2.2e-301 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
APMBIKAL_00437 1.1e-156 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
APMBIKAL_00438 1.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
APMBIKAL_00439 1.8e-156 safA M spore coat assembly protein SafA
APMBIKAL_00440 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
APMBIKAL_00441 1.6e-126 yebC K transcriptional regulatory protein
APMBIKAL_00442 1.5e-261 alsT E Sodium alanine symporter
APMBIKAL_00444 1.5e-50 S Family of unknown function (DUF5412)
APMBIKAL_00446 6.5e-119 yrzF T serine threonine protein kinase
APMBIKAL_00447 1.7e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
APMBIKAL_00448 5.3e-253 csbX EGP Major facilitator Superfamily
APMBIKAL_00449 4.8e-93 bofC S BofC C-terminal domain
APMBIKAL_00450 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
APMBIKAL_00451 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
APMBIKAL_00452 2.6e-18 yrzS S Protein of unknown function (DUF2905)
APMBIKAL_00453 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
APMBIKAL_00454 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
APMBIKAL_00455 1.1e-38 yajC U Preprotein translocase subunit YajC
APMBIKAL_00456 1.5e-74 yrzE S Protein of unknown function (DUF3792)
APMBIKAL_00457 1.6e-112 yrbG S membrane
APMBIKAL_00458 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APMBIKAL_00459 9.4e-49 yrzD S Post-transcriptional regulator
APMBIKAL_00460 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
APMBIKAL_00461 1.5e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
APMBIKAL_00462 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
APMBIKAL_00463 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
APMBIKAL_00464 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
APMBIKAL_00465 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
APMBIKAL_00466 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
APMBIKAL_00467 2.4e-260 lytH 3.5.1.28 M COG3103 SH3 domain protein
APMBIKAL_00469 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
APMBIKAL_00470 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
APMBIKAL_00471 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
APMBIKAL_00472 4.4e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
APMBIKAL_00473 1.2e-70 cymR K Transcriptional regulator
APMBIKAL_00474 9.7e-211 iscS 2.8.1.7 E Cysteine desulfurase
APMBIKAL_00475 6.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
APMBIKAL_00476 1.4e-15 S COG0457 FOG TPR repeat
APMBIKAL_00477 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
APMBIKAL_00478 3.9e-81 yrrD S protein conserved in bacteria
APMBIKAL_00479 9.8e-31 yrzR
APMBIKAL_00480 8e-08 S Protein of unknown function (DUF3918)
APMBIKAL_00481 7.6e-107 glnP P ABC transporter
APMBIKAL_00482 1.8e-108 gluC P ABC transporter
APMBIKAL_00483 1.6e-143 glnH ET Belongs to the bacterial solute-binding protein 3 family
APMBIKAL_00484 1.1e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
APMBIKAL_00485 1.3e-169 yrrI S AI-2E family transporter
APMBIKAL_00486 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
APMBIKAL_00487 1.7e-41 yrzL S Belongs to the UPF0297 family
APMBIKAL_00488 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
APMBIKAL_00489 1.2e-45 yrzB S Belongs to the UPF0473 family
APMBIKAL_00490 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
APMBIKAL_00491 2.3e-119 yrrM 2.1.1.104 S O-methyltransferase
APMBIKAL_00492 2.9e-173 yegQ O Peptidase U32
APMBIKAL_00493 1.4e-245 yegQ O COG0826 Collagenase and related proteases
APMBIKAL_00494 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
APMBIKAL_00495 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
APMBIKAL_00496 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
APMBIKAL_00497 1.6e-62 yrrS S Protein of unknown function (DUF1510)
APMBIKAL_00498 1e-25 yrzA S Protein of unknown function (DUF2536)
APMBIKAL_00499 7.6e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
APMBIKAL_00500 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
APMBIKAL_00501 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
APMBIKAL_00502 7.5e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
APMBIKAL_00503 4.6e-35 yrhC S YrhC-like protein
APMBIKAL_00504 9.2e-78 yrhD S Protein of unknown function (DUF1641)
APMBIKAL_00505 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
APMBIKAL_00506 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
APMBIKAL_00508 3e-142 focA P Formate nitrite
APMBIKAL_00511 4.5e-97 yrhH Q methyltransferase
APMBIKAL_00512 4.8e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
APMBIKAL_00513 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
APMBIKAL_00514 1.5e-46 yrhK S YrhK-like protein
APMBIKAL_00515 0.0 yrhL I Acyltransferase family
APMBIKAL_00516 2.5e-150 rsiV S Protein of unknown function (DUF3298)
APMBIKAL_00517 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
APMBIKAL_00518 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
APMBIKAL_00519 3.6e-106 yrhP E LysE type translocator
APMBIKAL_00520 1.1e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
APMBIKAL_00521 0.0 levR K PTS system fructose IIA component
APMBIKAL_00522 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
APMBIKAL_00523 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
APMBIKAL_00524 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
APMBIKAL_00525 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
APMBIKAL_00526 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
APMBIKAL_00527 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
APMBIKAL_00528 3.9e-198 adhA 1.1.1.1 C alcohol dehydrogenase
APMBIKAL_00529 1.6e-28 yphJ 4.1.1.44 S peroxiredoxin activity
APMBIKAL_00530 1.3e-46 yraB K helix_turn_helix, mercury resistance
APMBIKAL_00531 1.1e-49 yraD M Spore coat protein
APMBIKAL_00532 7.5e-26 yraE
APMBIKAL_00533 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
APMBIKAL_00534 6.4e-63 yraF M Spore coat protein
APMBIKAL_00535 1.5e-36 yraG
APMBIKAL_00536 9.4e-65 E Glyoxalase-like domain
APMBIKAL_00537 9.2e-61 T sh3 domain protein
APMBIKAL_00538 1.7e-60 T sh3 domain protein
APMBIKAL_00539 1.7e-153 S Alpha beta hydrolase
APMBIKAL_00540 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APMBIKAL_00541 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
APMBIKAL_00542 7.4e-13 yraM S PrpF protein
APMBIKAL_00543 5.5e-203 yraM S PrpF protein
APMBIKAL_00544 3.4e-163 yraN K Transcriptional regulator
APMBIKAL_00545 2.8e-225 yraO C Citrate transporter
APMBIKAL_00546 4.5e-188 yrpG C Aldo/keto reductase family
APMBIKAL_00547 2.2e-23 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
APMBIKAL_00548 3.1e-60 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
APMBIKAL_00549 1e-115 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
APMBIKAL_00551 4.8e-123 yrpD S Domain of unknown function, YrpD
APMBIKAL_00552 4.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
APMBIKAL_00553 1.5e-189 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
APMBIKAL_00554 3.2e-166 aadK G Streptomycin adenylyltransferase
APMBIKAL_00555 4.5e-91 yrdA S DinB family
APMBIKAL_00556 3.6e-56 S Protein of unknown function (DUF2568)
APMBIKAL_00557 1.2e-100 yrdC 3.5.1.19 Q Isochorismatase family
APMBIKAL_00559 9.2e-231 cypA C Cytochrome P450
APMBIKAL_00560 1.2e-15 yrdF K ribonuclease inhibitor
APMBIKAL_00561 6.3e-79 bkdR K helix_turn_helix ASNC type
APMBIKAL_00562 2.8e-137 azlC E AzlC protein
APMBIKAL_00563 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
APMBIKAL_00564 2.5e-226 brnQ E Component of the transport system for branched-chain amino acids
APMBIKAL_00565 7.2e-161 gltR K LysR substrate binding domain
APMBIKAL_00566 1.3e-66 yodA S tautomerase
APMBIKAL_00567 1.7e-152 czcD P COG1230 Co Zn Cd efflux system component
APMBIKAL_00568 2e-199 trkA P Oxidoreductase
APMBIKAL_00569 1.1e-158 yrdQ K Transcriptional regulator
APMBIKAL_00570 1.6e-169 yrdR EG EamA-like transporter family
APMBIKAL_00571 3.9e-16 S YrzO-like protein
APMBIKAL_00572 4.8e-230 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
APMBIKAL_00573 6.9e-83 bltD 2.3.1.57 K FR47-like protein
APMBIKAL_00574 1.1e-209 blt EGP Major facilitator Superfamily
APMBIKAL_00575 3.1e-150 bltR K helix_turn_helix, mercury resistance
APMBIKAL_00576 6.4e-107 yrkC G Cupin domain
APMBIKAL_00577 7.8e-39 yrkD S protein conserved in bacteria
APMBIKAL_00578 2.8e-82 yrkE O DsrE/DsrF/DrsH-like family
APMBIKAL_00579 1.8e-96 yrkF OP Belongs to the sulfur carrier protein TusA family
APMBIKAL_00581 2.7e-205 yrkH P Rhodanese Homology Domain
APMBIKAL_00582 5.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
APMBIKAL_00583 9.3e-112 yrkJ S membrane transporter protein
APMBIKAL_00584 7e-166 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
APMBIKAL_00585 6.3e-217 mepA V Multidrug transporter MatE
APMBIKAL_00586 3.3e-113 tetR3 K Transcriptional regulator
APMBIKAL_00587 6.1e-62 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APMBIKAL_00588 7.6e-94 yqaB E IrrE N-terminal-like domain
APMBIKAL_00590 1.2e-97 adk 2.7.4.3 F adenylate kinase activity
APMBIKAL_00592 1.1e-32 K sequence-specific DNA binding
APMBIKAL_00593 1.2e-17 K Helix-turn-helix XRE-family like proteins
APMBIKAL_00595 1.2e-103
APMBIKAL_00599 1e-173 yqaJ L YqaJ-like viral recombinase domain
APMBIKAL_00600 7.9e-149 recT L RecT family
APMBIKAL_00601 3.2e-119 3.1.3.16 L DnaD domain protein
APMBIKAL_00602 3e-164 xkdC L IstB-like ATP binding protein
APMBIKAL_00604 3.7e-70 rusA L Endodeoxyribonuclease RusA
APMBIKAL_00605 3.7e-31 yqaO S Phage-like element PBSX protein XtrA
APMBIKAL_00609 2.1e-76 L Transposase
APMBIKAL_00610 3.9e-22
APMBIKAL_00612 2.1e-42
APMBIKAL_00615 2.6e-77 yqaS L DNA packaging
APMBIKAL_00616 6.9e-245 S phage terminase, large subunit
APMBIKAL_00617 6.3e-290 yqbA S portal protein
APMBIKAL_00618 1.4e-151 S Phage Mu protein F like protein
APMBIKAL_00620 3.8e-115 yqbD 2.1.1.72 L Putative phage serine protease XkdF
APMBIKAL_00621 9.2e-167 xkdG S Phage capsid family
APMBIKAL_00622 6.7e-45 S YqbF, hypothetical protein domain
APMBIKAL_00623 3.9e-66 S Protein of unknown function (DUF3199)
APMBIKAL_00624 2.2e-63 yqbH S Domain of unknown function (DUF3599)
APMBIKAL_00625 3.3e-86 S Bacteriophage HK97-gp10, putative tail-component
APMBIKAL_00626 6.6e-75
APMBIKAL_00627 4.6e-25
APMBIKAL_00628 7.4e-253 xkdK S Phage tail sheath C-terminal domain
APMBIKAL_00629 3.6e-76 xkdM S Phage tail tube protein
APMBIKAL_00630 2.8e-68 S Phage XkdN-like tail assembly chaperone protein, TAC
APMBIKAL_00631 1.3e-16
APMBIKAL_00632 0.0 xkdO L Transglycosylase SLT domain
APMBIKAL_00633 7.6e-113 xkdP S Lysin motif
APMBIKAL_00634 6.7e-176 yqbQ 3.2.1.96 G NLP P60 protein
APMBIKAL_00635 1.6e-34 xkdR S Protein of unknown function (DUF2577)
APMBIKAL_00636 2.3e-109 5.1.1.13 M Belongs to the aspartate glutamate racemases family
APMBIKAL_00637 1.2e-65 xkdS S Protein of unknown function (DUF2634)
APMBIKAL_00638 3e-182 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
APMBIKAL_00639 1.5e-95 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
APMBIKAL_00640 7.6e-37
APMBIKAL_00641 4.1e-190
APMBIKAL_00642 1e-54 xkdW S XkdW protein
APMBIKAL_00643 1.5e-19
APMBIKAL_00644 1.7e-162 xepA
APMBIKAL_00645 2.6e-68 S Bacteriophage holin family
APMBIKAL_00646 3.4e-133 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
APMBIKAL_00648 2.2e-135 resA 3.1.21.5 L helicase
APMBIKAL_00649 5.1e-32
APMBIKAL_00650 5.5e-101 S Suppressor of fused protein (SUFU)
APMBIKAL_00651 6.6e-274 A Pre-toxin TG
APMBIKAL_00653 2.3e-156 S Aspartate phosphatase response regulator
APMBIKAL_00656 1.6e-54 arsR K ArsR family transcriptional regulator
APMBIKAL_00657 5.7e-66 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APMBIKAL_00658 8.7e-182 arsB 1.20.4.1 P Arsenic resistance protein
APMBIKAL_00659 4e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
APMBIKAL_00660 1.3e-22 L Helix-turn-helix domain of resolvase
APMBIKAL_00661 6e-140 yhfP 1.1.1.1 C Alcohol dehydrogenase GroES-like domain
APMBIKAL_00662 4.2e-64 K BetI-type transcriptional repressor, C-terminal
APMBIKAL_00663 1.2e-277 cisA2 L Recombinase
APMBIKAL_00664 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APMBIKAL_00665 2.6e-73 nucB M Deoxyribonuclease NucA/NucB
APMBIKAL_00666 5.1e-133 yqeB
APMBIKAL_00667 1.5e-169 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
APMBIKAL_00668 1.8e-105 yqeD S SNARE associated Golgi protein
APMBIKAL_00669 2e-132 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
APMBIKAL_00670 1.2e-140 yqeF E GDSL-like Lipase/Acylhydrolase
APMBIKAL_00672 5.3e-95 yqeG S hydrolase of the HAD superfamily
APMBIKAL_00673 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
APMBIKAL_00674 3.9e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
APMBIKAL_00675 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
APMBIKAL_00676 3.8e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
APMBIKAL_00677 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
APMBIKAL_00678 9.9e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
APMBIKAL_00679 2.9e-139 yqeM Q Methyltransferase
APMBIKAL_00680 2.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APMBIKAL_00681 4.3e-104 wza L COG1555 DNA uptake protein and related DNA-binding proteins
APMBIKAL_00682 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
APMBIKAL_00683 0.0 comEC S Competence protein ComEC
APMBIKAL_00684 4.1e-15 S YqzM-like protein
APMBIKAL_00685 9.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
APMBIKAL_00686 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
APMBIKAL_00687 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
APMBIKAL_00688 2e-222 spoIIP M stage II sporulation protein P
APMBIKAL_00689 3.6e-52 yqxA S Protein of unknown function (DUF3679)
APMBIKAL_00690 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
APMBIKAL_00691 1.6e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
APMBIKAL_00692 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
APMBIKAL_00693 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
APMBIKAL_00694 0.0 dnaK O Heat shock 70 kDa protein
APMBIKAL_00695 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
APMBIKAL_00696 5.4e-175 prmA J Methylates ribosomal protein L11
APMBIKAL_00697 1.4e-139 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
APMBIKAL_00698 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
APMBIKAL_00699 1.4e-157 yqeW P COG1283 Na phosphate symporter
APMBIKAL_00700 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
APMBIKAL_00701 2.5e-61 yqeY S Yqey-like protein
APMBIKAL_00702 1.5e-226 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
APMBIKAL_00703 4.3e-122 yqfA S UPF0365 protein
APMBIKAL_00704 3.7e-22 yqfB
APMBIKAL_00705 2.7e-45 yqfC S sporulation protein YqfC
APMBIKAL_00706 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
APMBIKAL_00707 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
APMBIKAL_00709 0.0 yqfF S membrane-associated HD superfamily hydrolase
APMBIKAL_00710 1.1e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
APMBIKAL_00711 3.5e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
APMBIKAL_00712 1.3e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
APMBIKAL_00713 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
APMBIKAL_00714 8.4e-19 S YqzL-like protein
APMBIKAL_00715 6.3e-145 recO L Involved in DNA repair and RecF pathway recombination
APMBIKAL_00716 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
APMBIKAL_00717 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
APMBIKAL_00718 4.5e-112 ccpN K CBS domain
APMBIKAL_00719 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
APMBIKAL_00720 4.5e-88 yaiI S Belongs to the UPF0178 family
APMBIKAL_00721 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
APMBIKAL_00722 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
APMBIKAL_00723 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
APMBIKAL_00724 6.8e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
APMBIKAL_00725 2.8e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
APMBIKAL_00726 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
APMBIKAL_00727 2.9e-14 yqfQ S YqfQ-like protein
APMBIKAL_00728 2.9e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
APMBIKAL_00729 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
APMBIKAL_00730 2.1e-36 yqfT S Protein of unknown function (DUF2624)
APMBIKAL_00731 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
APMBIKAL_00732 4.2e-77 zur P Belongs to the Fur family
APMBIKAL_00733 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
APMBIKAL_00734 4.3e-62 yqfX S membrane
APMBIKAL_00735 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
APMBIKAL_00736 4.4e-46 yqfZ M LysM domain
APMBIKAL_00737 3.9e-131 yqgB S Protein of unknown function (DUF1189)
APMBIKAL_00738 4e-73 yqgC S protein conserved in bacteria
APMBIKAL_00739 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
APMBIKAL_00740 1.3e-230 yqgE EGP Major facilitator superfamily
APMBIKAL_00741 0.0 pbpA 3.4.16.4 M penicillin-binding protein
APMBIKAL_00742 7e-142 pstS P Phosphate
APMBIKAL_00743 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
APMBIKAL_00744 4.4e-158 pstA P Phosphate transport system permease
APMBIKAL_00745 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
APMBIKAL_00746 4.9e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
APMBIKAL_00747 7.3e-72 yqzC S YceG-like family
APMBIKAL_00748 9.2e-51 yqzD
APMBIKAL_00750 1.2e-194 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
APMBIKAL_00751 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
APMBIKAL_00752 3.9e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
APMBIKAL_00753 2.5e-09 yqgO
APMBIKAL_00754 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
APMBIKAL_00755 4.3e-33 yqgQ S Protein conserved in bacteria
APMBIKAL_00756 5.2e-181 glcK 2.7.1.2 G Glucokinase
APMBIKAL_00757 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
APMBIKAL_00758 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
APMBIKAL_00759 2.7e-199 yqgU
APMBIKAL_00760 9.1e-50 yqgV S Thiamine-binding protein
APMBIKAL_00761 8.9e-23 yqgW S Protein of unknown function (DUF2759)
APMBIKAL_00762 4.7e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
APMBIKAL_00763 1.8e-37 yqgY S Protein of unknown function (DUF2626)
APMBIKAL_00764 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
APMBIKAL_00766 3.5e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
APMBIKAL_00767 1.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
APMBIKAL_00768 7.2e-175 corA P Mg2 transporter protein
APMBIKAL_00771 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
APMBIKAL_00772 1.7e-174 comGB NU COG1459 Type II secretory pathway, component PulF
APMBIKAL_00773 6.8e-47 comGC U Required for transformation and DNA binding
APMBIKAL_00774 1.2e-68 gspH NU protein transport across the cell outer membrane
APMBIKAL_00775 1.3e-57 comGE
APMBIKAL_00776 1.3e-34 comGF U Putative Competence protein ComGF
APMBIKAL_00777 1.2e-43 S ComG operon protein 7
APMBIKAL_00778 5.2e-26 yqzE S YqzE-like protein
APMBIKAL_00779 7.3e-54 yqzG S Protein of unknown function (DUF3889)
APMBIKAL_00780 4.3e-114 yqxM
APMBIKAL_00781 2.5e-58 sipW 3.4.21.89 U Signal peptidase
APMBIKAL_00782 2.5e-141 tasA S Cell division protein FtsN
APMBIKAL_00783 1e-54 sinR K transcriptional
APMBIKAL_00784 1.2e-24 sinI S Anti-repressor SinI
APMBIKAL_00785 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
APMBIKAL_00786 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
APMBIKAL_00787 6.9e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
APMBIKAL_00788 2.2e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
APMBIKAL_00789 5.3e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
APMBIKAL_00790 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
APMBIKAL_00791 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
APMBIKAL_00792 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
APMBIKAL_00793 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
APMBIKAL_00794 2.2e-61 yqhP
APMBIKAL_00795 8e-174 yqhQ S Protein of unknown function (DUF1385)
APMBIKAL_00796 2.3e-93 yqhR S Conserved membrane protein YqhR
APMBIKAL_00797 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
APMBIKAL_00798 3.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
APMBIKAL_00799 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
APMBIKAL_00800 7.9e-37 yqhV S Protein of unknown function (DUF2619)
APMBIKAL_00801 8.8e-170 spoIIIAA S stage III sporulation protein AA
APMBIKAL_00802 1.1e-84 spoIIIAB S Stage III sporulation protein
APMBIKAL_00803 7.6e-29 spoIIIAC S stage III sporulation protein AC
APMBIKAL_00804 2.3e-58 spoIIIAD S Stage III sporulation protein AD
APMBIKAL_00805 1.3e-197 spoIIIAE S stage III sporulation protein AE
APMBIKAL_00806 9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
APMBIKAL_00807 1.9e-108 spoIIIAG S stage III sporulation protein AG
APMBIKAL_00808 9.9e-91 spoIIIAH S SpoIIIAH-like protein
APMBIKAL_00809 2.6e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
APMBIKAL_00810 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
APMBIKAL_00811 8.9e-66 yqhY S protein conserved in bacteria
APMBIKAL_00812 7.4e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
APMBIKAL_00813 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
APMBIKAL_00814 3.1e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
APMBIKAL_00815 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
APMBIKAL_00816 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
APMBIKAL_00817 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
APMBIKAL_00818 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
APMBIKAL_00819 1.7e-78 argR K Regulates arginine biosynthesis genes
APMBIKAL_00820 2.2e-310 recN L May be involved in recombinational repair of damaged DNA
APMBIKAL_00821 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
APMBIKAL_00822 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
APMBIKAL_00824 4e-212 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
APMBIKAL_00825 6e-27
APMBIKAL_00826 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
APMBIKAL_00827 8.9e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
APMBIKAL_00828 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
APMBIKAL_00829 6.8e-156 hbdA 1.1.1.157 I Dehydrogenase
APMBIKAL_00830 1.8e-212 mmgC I acyl-CoA dehydrogenase
APMBIKAL_00831 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
APMBIKAL_00832 2.2e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
APMBIKAL_00833 3e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
APMBIKAL_00834 2.6e-33 yqzF S Protein of unknown function (DUF2627)
APMBIKAL_00835 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
APMBIKAL_00836 5.1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
APMBIKAL_00837 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
APMBIKAL_00838 5.1e-201 buk 2.7.2.7 C Belongs to the acetokinase family
APMBIKAL_00839 3.7e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
APMBIKAL_00840 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
APMBIKAL_00841 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
APMBIKAL_00842 1.1e-226 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
APMBIKAL_00843 3.7e-151 bmrR K helix_turn_helix, mercury resistance
APMBIKAL_00844 7.9e-208 norA EGP Major facilitator Superfamily
APMBIKAL_00845 3.4e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
APMBIKAL_00846 9.3e-77 yqiW S Belongs to the UPF0403 family
APMBIKAL_00847 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
APMBIKAL_00848 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
APMBIKAL_00849 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
APMBIKAL_00850 7.3e-175 yqjA S Putative aromatic acid exporter C-terminal domain
APMBIKAL_00851 1.4e-98 yqjB S protein conserved in bacteria
APMBIKAL_00853 3.3e-71 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
APMBIKAL_00854 2.3e-287 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
APMBIKAL_00855 4.7e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
APMBIKAL_00856 7.5e-140 yqjF S Uncharacterized conserved protein (COG2071)
APMBIKAL_00857 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APMBIKAL_00858 4.5e-24 yqzJ
APMBIKAL_00859 1.6e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
APMBIKAL_00860 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
APMBIKAL_00861 2.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
APMBIKAL_00862 3.8e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
APMBIKAL_00863 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
APMBIKAL_00864 2.1e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
APMBIKAL_00865 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
APMBIKAL_00866 0.0 rocB E arginine degradation protein
APMBIKAL_00867 6.2e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APMBIKAL_00868 3.1e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
APMBIKAL_00869 8.6e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
APMBIKAL_00870 1.9e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
APMBIKAL_00871 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
APMBIKAL_00872 4.6e-72 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APMBIKAL_00874 3.4e-225 yqjV G Major Facilitator Superfamily
APMBIKAL_00876 4.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
APMBIKAL_00877 5.7e-50 S YolD-like protein
APMBIKAL_00878 4e-86 yqjY K acetyltransferase
APMBIKAL_00879 6.8e-59 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
APMBIKAL_00880 1.7e-193 yqkA K GrpB protein
APMBIKAL_00881 2.8e-54 yqkB S Belongs to the HesB IscA family
APMBIKAL_00882 4.6e-38 yqkC S Protein of unknown function (DUF2552)
APMBIKAL_00883 2.7e-171 yqkD S COG1073 Hydrolases of the alpha beta superfamily
APMBIKAL_00884 3.1e-12 yqkE S Protein of unknown function (DUF3886)
APMBIKAL_00885 7.4e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
APMBIKAL_00887 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
APMBIKAL_00888 5.3e-220 yqxK 3.6.4.12 L DNA helicase
APMBIKAL_00889 4.5e-58 ansR K Transcriptional regulator
APMBIKAL_00890 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
APMBIKAL_00891 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
APMBIKAL_00892 3.1e-235 mleN C Na H antiporter
APMBIKAL_00893 5.5e-242 mleA 1.1.1.38 C malic enzyme
APMBIKAL_00894 2.2e-31 yqkK
APMBIKAL_00895 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
APMBIKAL_00896 2.4e-80 fur P Belongs to the Fur family
APMBIKAL_00897 3.7e-37 S Protein of unknown function (DUF4227)
APMBIKAL_00898 2.6e-166 xerD L recombinase XerD
APMBIKAL_00899 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
APMBIKAL_00900 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
APMBIKAL_00901 6.3e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
APMBIKAL_00902 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
APMBIKAL_00903 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
APMBIKAL_00904 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APMBIKAL_00905 9.6e-112 spoVAA S Stage V sporulation protein AA
APMBIKAL_00906 1e-67 spoVAB S Stage V sporulation protein AB
APMBIKAL_00907 2.3e-78 spoVAC S stage V sporulation protein AC
APMBIKAL_00908 9e-192 spoVAD I Stage V sporulation protein AD
APMBIKAL_00909 2.2e-57 spoVAEB S stage V sporulation protein
APMBIKAL_00910 1.4e-110 spoVAEA S stage V sporulation protein
APMBIKAL_00911 1.4e-273 spoVAF EG Stage V sporulation protein AF
APMBIKAL_00912 5.7e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
APMBIKAL_00913 8.1e-149 ypuA S Secreted protein
APMBIKAL_00914 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
APMBIKAL_00919 1.9e-25 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
APMBIKAL_00922 7e-16 S SNARE associated Golgi protein
APMBIKAL_00923 6.6e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
APMBIKAL_00924 7.8e-97 sipT 3.4.21.89 U Belongs to the peptidase S26 family
APMBIKAL_00925 1.7e-54 ypuD
APMBIKAL_00926 7.9e-202 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
APMBIKAL_00927 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
APMBIKAL_00928 1.9e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
APMBIKAL_00929 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
APMBIKAL_00930 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APMBIKAL_00931 1.6e-91 ypuF S Domain of unknown function (DUF309)
APMBIKAL_00932 2.4e-128 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
APMBIKAL_00933 2.1e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
APMBIKAL_00934 4e-98 ypuI S Protein of unknown function (DUF3907)
APMBIKAL_00935 1.8e-212 dacB 3.4.16.4 M Belongs to the peptidase S11 family
APMBIKAL_00936 3.5e-103 spmA S Spore maturation protein
APMBIKAL_00937 1.9e-87 spmB S Spore maturation protein
APMBIKAL_00938 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
APMBIKAL_00939 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
APMBIKAL_00940 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
APMBIKAL_00941 8.8e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
APMBIKAL_00942 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APMBIKAL_00943 0.0 resE 2.7.13.3 T Histidine kinase
APMBIKAL_00944 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
APMBIKAL_00945 2.3e-188 rsiX
APMBIKAL_00946 2.9e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
APMBIKAL_00947 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APMBIKAL_00949 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
APMBIKAL_00950 4.7e-41 fer C Ferredoxin
APMBIKAL_00951 1.9e-200 ypbB 5.1.3.1 S protein conserved in bacteria
APMBIKAL_00952 9.2e-286 recQ 3.6.4.12 L DNA helicase
APMBIKAL_00953 2.4e-99 ypbD S metal-dependent membrane protease
APMBIKAL_00954 5.8e-63 ypbE M Lysin motif
APMBIKAL_00955 2.8e-81 ypbF S Protein of unknown function (DUF2663)
APMBIKAL_00956 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
APMBIKAL_00957 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
APMBIKAL_00958 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
APMBIKAL_00959 3.9e-176 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
APMBIKAL_00960 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
APMBIKAL_00961 7.5e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
APMBIKAL_00962 2.1e-252 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
APMBIKAL_00963 1.1e-110 ypfA M Flagellar protein YcgR
APMBIKAL_00964 1.8e-23 S Family of unknown function (DUF5359)
APMBIKAL_00965 1.6e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
APMBIKAL_00966 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
APMBIKAL_00967 2.5e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
APMBIKAL_00968 1.4e-07 S YpzI-like protein
APMBIKAL_00969 3.9e-102 yphA
APMBIKAL_00970 2.5e-161 seaA S YIEGIA protein
APMBIKAL_00971 1.6e-28 ypzH
APMBIKAL_00972 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
APMBIKAL_00973 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
APMBIKAL_00974 1.6e-18 yphE S Protein of unknown function (DUF2768)
APMBIKAL_00975 5.4e-138 yphF
APMBIKAL_00976 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
APMBIKAL_00977 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
APMBIKAL_00978 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
APMBIKAL_00979 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
APMBIKAL_00980 2.8e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
APMBIKAL_00981 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
APMBIKAL_00982 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
APMBIKAL_00983 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
APMBIKAL_00984 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
APMBIKAL_00985 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
APMBIKAL_00986 5.8e-205 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
APMBIKAL_00987 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
APMBIKAL_00988 4e-292 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
APMBIKAL_00989 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
APMBIKAL_00990 1.4e-112 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
APMBIKAL_00991 1.2e-117 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
APMBIKAL_00992 5.2e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
APMBIKAL_00993 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
APMBIKAL_00994 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
APMBIKAL_00995 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
APMBIKAL_00996 3.4e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
APMBIKAL_00997 4.1e-234 S COG0457 FOG TPR repeat
APMBIKAL_00998 1.1e-98 ypiB S Belongs to the UPF0302 family
APMBIKAL_00999 1.2e-76 ypiF S Protein of unknown function (DUF2487)
APMBIKAL_01000 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
APMBIKAL_01001 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
APMBIKAL_01002 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
APMBIKAL_01003 9.9e-98 ypjA S membrane
APMBIKAL_01004 6.1e-143 ypjB S sporulation protein
APMBIKAL_01005 2.4e-156 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
APMBIKAL_01006 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
APMBIKAL_01007 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
APMBIKAL_01008 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
APMBIKAL_01009 2.4e-127 bshB1 S proteins, LmbE homologs
APMBIKAL_01010 6.9e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
APMBIKAL_01011 7e-220 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
APMBIKAL_01012 2.5e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
APMBIKAL_01013 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
APMBIKAL_01014 4.7e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
APMBIKAL_01015 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
APMBIKAL_01016 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
APMBIKAL_01017 6.7e-23 ypmA S Protein of unknown function (DUF4264)
APMBIKAL_01018 2.2e-79 ypmB S protein conserved in bacteria
APMBIKAL_01019 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
APMBIKAL_01020 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
APMBIKAL_01021 5.7e-129 dnaD L DNA replication protein DnaD
APMBIKAL_01022 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
APMBIKAL_01023 1.8e-92 ypoC
APMBIKAL_01024 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
APMBIKAL_01025 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
APMBIKAL_01026 3.7e-187 yppC S Protein of unknown function (DUF2515)
APMBIKAL_01029 5.7e-11 yppE S Bacterial domain of unknown function (DUF1798)
APMBIKAL_01031 5.1e-47 yppG S YppG-like protein
APMBIKAL_01032 7.3e-71 hspX O Belongs to the small heat shock protein (HSP20) family
APMBIKAL_01033 1e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
APMBIKAL_01034 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
APMBIKAL_01035 5.1e-237 yprB L RNase_H superfamily
APMBIKAL_01036 8.2e-91 ypsA S Belongs to the UPF0398 family
APMBIKAL_01037 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
APMBIKAL_01038 3.5e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
APMBIKAL_01040 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
APMBIKAL_01041 2.3e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APMBIKAL_01042 4.1e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
APMBIKAL_01043 4.1e-184 ptxS K transcriptional
APMBIKAL_01044 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
APMBIKAL_01045 8.6e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
APMBIKAL_01046 1.9e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
APMBIKAL_01047 2.3e-292 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
APMBIKAL_01048 1.1e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
APMBIKAL_01049 1.5e-226 pbuX F xanthine
APMBIKAL_01050 2.4e-206 bcsA Q Naringenin-chalcone synthase
APMBIKAL_01051 1.5e-86 ypbQ S protein conserved in bacteria
APMBIKAL_01053 0.0 ypbR S Dynamin family
APMBIKAL_01054 2.9e-38 ypbS S Protein of unknown function (DUF2533)
APMBIKAL_01055 2e-07
APMBIKAL_01056 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
APMBIKAL_01058 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
APMBIKAL_01059 4.5e-106 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
APMBIKAL_01060 1.7e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
APMBIKAL_01061 3e-29 ypeQ S Zinc-finger
APMBIKAL_01062 8.1e-31 S Protein of unknown function (DUF2564)
APMBIKAL_01063 3.8e-16 degR
APMBIKAL_01064 7.9e-31 cspD K Cold-shock protein
APMBIKAL_01065 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
APMBIKAL_01067 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
APMBIKAL_01068 1.7e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
APMBIKAL_01069 2.1e-106 ypgQ S phosphohydrolase
APMBIKAL_01070 1.2e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
APMBIKAL_01071 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
APMBIKAL_01072 1.7e-75 yphP S Belongs to the UPF0403 family
APMBIKAL_01073 1.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
APMBIKAL_01074 7.8e-114 ypjP S YpjP-like protein
APMBIKAL_01075 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
APMBIKAL_01076 1.1e-155 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
APMBIKAL_01077 1.8e-92 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
APMBIKAL_01078 1.1e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
APMBIKAL_01079 4.2e-110 hlyIII S protein, Hemolysin III
APMBIKAL_01080 6.1e-185 pspF K Transcriptional regulator
APMBIKAL_01081 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
APMBIKAL_01082 3.1e-40 ypmP S Protein of unknown function (DUF2535)
APMBIKAL_01083 9.7e-106 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
APMBIKAL_01084 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
APMBIKAL_01085 1.1e-98 ypmS S protein conserved in bacteria
APMBIKAL_01086 5.5e-29 ypmT S Uncharacterized ympT
APMBIKAL_01087 4.9e-222 mepA V MATE efflux family protein
APMBIKAL_01088 1.6e-70 ypoP K transcriptional
APMBIKAL_01089 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
APMBIKAL_01090 2.9e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
APMBIKAL_01091 2.5e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
APMBIKAL_01092 7.5e-211 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
APMBIKAL_01093 4.1e-186 cgeB S Spore maturation protein
APMBIKAL_01094 1.2e-65 cgeA
APMBIKAL_01095 5.9e-38 cgeC
APMBIKAL_01096 7.2e-255 cgeD M maturation of the outermost layer of the spore
APMBIKAL_01097 5.9e-143 yiiD K acetyltransferase
APMBIKAL_01099 2.3e-248 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
APMBIKAL_01100 6.5e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
APMBIKAL_01101 8e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
APMBIKAL_01102 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
APMBIKAL_01103 6.7e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
APMBIKAL_01104 1.1e-277 kamA 5.4.3.2 E lysine 2,3-aminomutase
APMBIKAL_01105 6.4e-47 yokU S YokU-like protein, putative antitoxin
APMBIKAL_01106 1.4e-36 yozE S Belongs to the UPF0346 family
APMBIKAL_01107 1.6e-123 yodN
APMBIKAL_01109 6.3e-24 yozD S YozD-like protein
APMBIKAL_01110 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
APMBIKAL_01111 3.6e-54 yodL S YodL-like
APMBIKAL_01112 5.3e-09
APMBIKAL_01113 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
APMBIKAL_01114 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
APMBIKAL_01115 5.2e-24 yodI
APMBIKAL_01116 2.8e-128 yodH Q Methyltransferase
APMBIKAL_01117 2.8e-252 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
APMBIKAL_01118 5.6e-267 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APMBIKAL_01119 6.2e-28 S Protein of unknown function (DUF3311)
APMBIKAL_01120 6.7e-170 yodE E COG0346 Lactoylglutathione lyase and related lyases
APMBIKAL_01121 2.1e-111 mhqD S Carboxylesterase
APMBIKAL_01122 1.4e-107 yodC C nitroreductase
APMBIKAL_01123 4.4e-55 yodB K transcriptional
APMBIKAL_01124 8e-64 yodA S tautomerase
APMBIKAL_01125 1.4e-205 gntP EG COG2610 H gluconate symporter and related permeases
APMBIKAL_01126 3.4e-09
APMBIKAL_01127 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
APMBIKAL_01128 5.6e-161 rarD S -transporter
APMBIKAL_01129 1.5e-43
APMBIKAL_01130 2.2e-60 yojF S Protein of unknown function (DUF1806)
APMBIKAL_01131 2.1e-125 yojG S deacetylase
APMBIKAL_01132 3.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
APMBIKAL_01133 7.2e-245 norM V Multidrug efflux pump
APMBIKAL_01135 5.8e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
APMBIKAL_01136 1.5e-230 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
APMBIKAL_01137 3.9e-197 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
APMBIKAL_01138 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
APMBIKAL_01139 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
APMBIKAL_01140 0.0 yojO P Von Willebrand factor
APMBIKAL_01141 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
APMBIKAL_01142 9.1e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
APMBIKAL_01143 1.1e-167 yocS S -transporter
APMBIKAL_01144 4.5e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
APMBIKAL_01145 1.3e-164 sodA 1.15.1.1 P Superoxide dismutase
APMBIKAL_01146 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
APMBIKAL_01147 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
APMBIKAL_01148 2.7e-31 yozC
APMBIKAL_01149 4.2e-56 yozO S Bacterial PH domain
APMBIKAL_01150 1.9e-36 yocN
APMBIKAL_01151 1.1e-40 yozN
APMBIKAL_01152 1.1e-86 yocM O Belongs to the small heat shock protein (HSP20) family
APMBIKAL_01153 6.2e-32
APMBIKAL_01154 6.4e-54 yocL
APMBIKAL_01155 3.3e-83 dksA T general stress protein
APMBIKAL_01156 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
APMBIKAL_01157 0.0 recQ 3.6.4.12 L DNA helicase
APMBIKAL_01158 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
APMBIKAL_01159 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APMBIKAL_01160 1.7e-196 desK 2.7.13.3 T Histidine kinase
APMBIKAL_01161 1e-201 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
APMBIKAL_01162 1.1e-186 yocD 3.4.17.13 V peptidase S66
APMBIKAL_01163 3.6e-93 yocC
APMBIKAL_01164 2.1e-143
APMBIKAL_01165 1.5e-92 yozB S membrane
APMBIKAL_01166 1.3e-117 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
APMBIKAL_01167 1e-51 czrA K transcriptional
APMBIKAL_01168 7.2e-95 yobW
APMBIKAL_01169 1.9e-175 yobV K WYL domain
APMBIKAL_01170 7.1e-86 yobU K Bacterial transcription activator, effector binding domain
APMBIKAL_01171 6.1e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
APMBIKAL_01172 3.3e-98 yobS K Transcriptional regulator
APMBIKAL_01173 4.5e-140 yobR 2.3.1.1 J FR47-like protein
APMBIKAL_01174 3.6e-134 yobQ K helix_turn_helix, arabinose operon control protein
APMBIKAL_01175 9.3e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
APMBIKAL_01176 1.5e-277 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
APMBIKAL_01177 5.1e-91 yokH G SMI1 / KNR4 family
APMBIKAL_01178 6.5e-10 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
APMBIKAL_01179 1.5e-19
APMBIKAL_01181 6e-46
APMBIKAL_01183 8.1e-208 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
APMBIKAL_01185 4.1e-206 S aspartate phosphatase
APMBIKAL_01193 7.8e-08
APMBIKAL_01201 2e-08
APMBIKAL_01205 2.7e-143 spo0M S COG4326 Sporulation control protein
APMBIKAL_01206 1.2e-26
APMBIKAL_01207 2.7e-131 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
APMBIKAL_01208 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
APMBIKAL_01209 2.2e-262 ygaK C Berberine and berberine like
APMBIKAL_01211 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
APMBIKAL_01212 6.2e-144 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
APMBIKAL_01213 2.1e-169 ssuA M Sulfonate ABC transporter
APMBIKAL_01214 2.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
APMBIKAL_01215 5.3e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
APMBIKAL_01217 5e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
APMBIKAL_01218 1.7e-76 ygaO
APMBIKAL_01219 4.4e-29 K Transcriptional regulator
APMBIKAL_01221 1.9e-112 yhzB S B3/4 domain
APMBIKAL_01222 3.9e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
APMBIKAL_01223 1.1e-175 yhbB S Putative amidase domain
APMBIKAL_01224 1.3e-84 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
APMBIKAL_01225 2.3e-108 yhbD K Protein of unknown function (DUF4004)
APMBIKAL_01226 1.4e-61 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
APMBIKAL_01227 7.2e-71 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
APMBIKAL_01228 0.0 prkA T Ser protein kinase
APMBIKAL_01229 2.5e-225 yhbH S Belongs to the UPF0229 family
APMBIKAL_01230 8.3e-76 yhbI K DNA-binding transcription factor activity
APMBIKAL_01231 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
APMBIKAL_01232 3.1e-271 yhcA EGP Major facilitator Superfamily
APMBIKAL_01233 1.4e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
APMBIKAL_01234 2.8e-37 yhcC
APMBIKAL_01235 1.3e-54
APMBIKAL_01236 6.6e-60 yhcF K Transcriptional regulator
APMBIKAL_01237 4e-122 yhcG V ABC transporter, ATP-binding protein
APMBIKAL_01238 7.7e-166 yhcH V ABC transporter, ATP-binding protein
APMBIKAL_01239 5.6e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
APMBIKAL_01240 1e-30 cspB K Cold-shock protein
APMBIKAL_01241 2.2e-151 metQ M Belongs to the nlpA lipoprotein family
APMBIKAL_01242 3.4e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
APMBIKAL_01243 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
APMBIKAL_01244 1.1e-40 yhcM
APMBIKAL_01245 6e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
APMBIKAL_01246 7.3e-167 yhcP
APMBIKAL_01247 1.5e-99 yhcQ M Spore coat protein
APMBIKAL_01248 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
APMBIKAL_01249 3.9e-102 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
APMBIKAL_01250 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
APMBIKAL_01251 6e-67 yhcU S Family of unknown function (DUF5365)
APMBIKAL_01252 3.8e-67 yhcV S COG0517 FOG CBS domain
APMBIKAL_01253 1.3e-119 yhcW 5.4.2.6 S hydrolase
APMBIKAL_01254 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
APMBIKAL_01255 5.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
APMBIKAL_01256 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
APMBIKAL_01257 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
APMBIKAL_01258 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
APMBIKAL_01259 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
APMBIKAL_01260 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
APMBIKAL_01261 1.4e-212 yhcY 2.7.13.3 T Histidine kinase
APMBIKAL_01262 1.7e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APMBIKAL_01263 1.9e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
APMBIKAL_01264 1.2e-38 yhdB S YhdB-like protein
APMBIKAL_01265 4.5e-52 yhdC S Protein of unknown function (DUF3889)
APMBIKAL_01266 2.3e-188 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
APMBIKAL_01267 1e-75 nsrR K Transcriptional regulator
APMBIKAL_01268 1.3e-237 ygxB M Conserved TM helix
APMBIKAL_01269 2.1e-276 ycgB S Stage V sporulation protein R
APMBIKAL_01270 5.4e-256 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
APMBIKAL_01271 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
APMBIKAL_01272 3.8e-162 citR K Transcriptional regulator
APMBIKAL_01273 1.2e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
APMBIKAL_01274 9.2e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APMBIKAL_01275 1e-249 yhdG E amino acid
APMBIKAL_01276 1.3e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
APMBIKAL_01277 7.2e-272 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
APMBIKAL_01278 5.5e-74 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APMBIKAL_01279 8.1e-45 yhdK S Sigma-M inhibitor protein
APMBIKAL_01280 2.5e-200 yhdL S Sigma factor regulator N-terminal
APMBIKAL_01281 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
APMBIKAL_01282 6.3e-190 yhdN C Aldo keto reductase
APMBIKAL_01283 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
APMBIKAL_01284 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
APMBIKAL_01285 4.1e-74 cueR K transcriptional
APMBIKAL_01286 1.7e-221 yhdR 2.6.1.1 E Aminotransferase
APMBIKAL_01287 5.6e-245 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
APMBIKAL_01288 4.9e-44 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
APMBIKAL_01289 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
APMBIKAL_01290 6.2e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
APMBIKAL_01292 5.6e-203 yhdY M Mechanosensitive ion channel
APMBIKAL_01293 2.6e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
APMBIKAL_01294 1.7e-151 yheN G deacetylase
APMBIKAL_01295 1.2e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
APMBIKAL_01296 3.5e-231 nhaC C Na H antiporter
APMBIKAL_01297 3.4e-84 nhaX T Belongs to the universal stress protein A family
APMBIKAL_01298 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
APMBIKAL_01299 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
APMBIKAL_01300 2.9e-108 yheG GM NAD(P)H-binding
APMBIKAL_01301 6.3e-28 sspB S spore protein
APMBIKAL_01302 1.3e-36 yheE S Family of unknown function (DUF5342)
APMBIKAL_01303 4.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
APMBIKAL_01304 4.3e-216 yheC HJ YheC/D like ATP-grasp
APMBIKAL_01305 2.2e-202 yheB S Belongs to the UPF0754 family
APMBIKAL_01306 9.5e-48 yheA S Belongs to the UPF0342 family
APMBIKAL_01307 9.8e-205 yhaZ L DNA alkylation repair enzyme
APMBIKAL_01308 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
APMBIKAL_01309 4.6e-293 hemZ H coproporphyrinogen III oxidase
APMBIKAL_01310 2.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
APMBIKAL_01311 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
APMBIKAL_01313 2.1e-132 yhaR 5.3.3.18 I enoyl-CoA hydratase
APMBIKAL_01314 1.1e-26 S YhzD-like protein
APMBIKAL_01315 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
APMBIKAL_01316 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
APMBIKAL_01317 8.2e-224 yhaO L DNA repair exonuclease
APMBIKAL_01318 0.0 yhaN L AAA domain
APMBIKAL_01319 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
APMBIKAL_01320 1.6e-21 yhaL S Sporulation protein YhaL
APMBIKAL_01321 3.2e-116 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
APMBIKAL_01322 8.7e-90 yhaK S Putative zincin peptidase
APMBIKAL_01323 1.3e-54 yhaI S Protein of unknown function (DUF1878)
APMBIKAL_01324 1e-113 hpr K Negative regulator of protease production and sporulation
APMBIKAL_01325 7e-39 yhaH S YtxH-like protein
APMBIKAL_01326 3.6e-80 trpP S Tryptophan transporter TrpP
APMBIKAL_01327 2.4e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
APMBIKAL_01328 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
APMBIKAL_01329 8.8e-136 ecsA V transporter (ATP-binding protein)
APMBIKAL_01330 5.9e-214 ecsB U ABC transporter
APMBIKAL_01331 6.9e-114 ecsC S EcsC protein family
APMBIKAL_01332 8.3e-229 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
APMBIKAL_01333 7.4e-245 yhfA C membrane
APMBIKAL_01334 1.2e-30 1.15.1.2 C Rubrerythrin
APMBIKAL_01335 2.9e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
APMBIKAL_01336 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
APMBIKAL_01337 6.3e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
APMBIKAL_01338 3.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
APMBIKAL_01339 3.5e-266 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
APMBIKAL_01340 2.7e-100 yhgD K Transcriptional regulator
APMBIKAL_01341 3.8e-238 yhgE S YhgE Pip N-terminal domain protein
APMBIKAL_01342 6.7e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
APMBIKAL_01343 4.9e-137 yhfC S Putative membrane peptidase family (DUF2324)
APMBIKAL_01344 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
APMBIKAL_01345 8.4e-72 3.4.13.21 S ASCH
APMBIKAL_01346 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
APMBIKAL_01347 6.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
APMBIKAL_01348 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
APMBIKAL_01349 1.9e-110 yhfK GM NmrA-like family
APMBIKAL_01350 2e-299 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
APMBIKAL_01351 1.9e-65 yhfM
APMBIKAL_01352 5.3e-237 yhfN 3.4.24.84 O Peptidase M48
APMBIKAL_01353 2.3e-204 aprE 3.4.21.62 O Belongs to the peptidase S8 family
APMBIKAL_01354 4.3e-77 VY92_01935 K acetyltransferase
APMBIKAL_01355 1.8e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
APMBIKAL_01356 4.3e-159 yfmC M Periplasmic binding protein
APMBIKAL_01357 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
APMBIKAL_01358 1.1e-195 vraB 2.3.1.9 I Belongs to the thiolase family
APMBIKAL_01359 4.3e-272 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
APMBIKAL_01360 4.2e-90 bioY S BioY family
APMBIKAL_01361 1.7e-182 hemAT NT chemotaxis protein
APMBIKAL_01362 2.6e-299 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
APMBIKAL_01363 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APMBIKAL_01364 1.3e-32 yhzC S IDEAL
APMBIKAL_01365 4.2e-109 comK K Competence transcription factor
APMBIKAL_01366 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
APMBIKAL_01367 7.8e-42 yhjA S Excalibur calcium-binding domain
APMBIKAL_01368 5.7e-264 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APMBIKAL_01369 6.9e-27 yhjC S Protein of unknown function (DUF3311)
APMBIKAL_01370 6.7e-60 yhjD
APMBIKAL_01371 9.1e-110 yhjE S SNARE associated Golgi protein
APMBIKAL_01372 3.4e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
APMBIKAL_01373 6.2e-282 yhjG CH FAD binding domain
APMBIKAL_01374 6.5e-93 yhjH K helix_turn_helix multiple antibiotic resistance protein
APMBIKAL_01375 4.9e-213 glcP G Major Facilitator Superfamily
APMBIKAL_01376 5.5e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
APMBIKAL_01377 2.6e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
APMBIKAL_01378 1.1e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
APMBIKAL_01379 2.9e-187 yhjM 5.1.1.1 K Transcriptional regulator
APMBIKAL_01380 4.2e-201 abrB S membrane
APMBIKAL_01381 1.1e-212 EGP Transmembrane secretion effector
APMBIKAL_01382 0.0 S Sugar transport-related sRNA regulator N-term
APMBIKAL_01383 2.2e-78 yhjR S Rubrerythrin
APMBIKAL_01384 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
APMBIKAL_01385 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
APMBIKAL_01386 3.7e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
APMBIKAL_01387 0.0 sbcC L COG0419 ATPase involved in DNA repair
APMBIKAL_01388 2.1e-48 yisB V COG1403 Restriction endonuclease
APMBIKAL_01389 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
APMBIKAL_01390 2e-65 gerPE S Spore germination protein GerPE
APMBIKAL_01391 6.3e-24 gerPD S Spore germination protein
APMBIKAL_01392 1.8e-54 gerPC S Spore germination protein
APMBIKAL_01393 4e-34 gerPB S cell differentiation
APMBIKAL_01394 1.9e-33 gerPA S Spore germination protein
APMBIKAL_01395 1.5e-22 yisI S Spo0E like sporulation regulatory protein
APMBIKAL_01396 6.1e-171 cotH M Spore Coat
APMBIKAL_01397 6e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
APMBIKAL_01398 3e-57 yisL S UPF0344 protein
APMBIKAL_01399 0.0 wprA O Belongs to the peptidase S8 family
APMBIKAL_01400 4.8e-102 yisN S Protein of unknown function (DUF2777)
APMBIKAL_01401 0.0 asnO 6.3.5.4 E Asparagine synthase
APMBIKAL_01402 2.1e-88 yizA S Damage-inducible protein DinB
APMBIKAL_01403 7.7e-146 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
APMBIKAL_01404 4e-243 yisQ V Mate efflux family protein
APMBIKAL_01405 2.7e-160 yisR K Transcriptional regulator
APMBIKAL_01406 1.3e-182 purR K helix_turn _helix lactose operon repressor
APMBIKAL_01407 1.4e-192 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
APMBIKAL_01408 3.1e-92 yisT S DinB family
APMBIKAL_01409 1.9e-107 argO S Lysine exporter protein LysE YggA
APMBIKAL_01410 1.2e-277 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
APMBIKAL_01411 2e-35 mcbG S Pentapeptide repeats (9 copies)
APMBIKAL_01412 4.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
APMBIKAL_01413 1.4e-112 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
APMBIKAL_01414 2.7e-232 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
APMBIKAL_01415 2.1e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
APMBIKAL_01416 1.6e-120 comB 3.1.3.71 H Belongs to the ComB family
APMBIKAL_01417 7.1e-141 yitD 4.4.1.19 S synthase
APMBIKAL_01418 1.9e-107 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
APMBIKAL_01419 5.6e-219 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
APMBIKAL_01420 5.7e-228 yitG EGP Major facilitator Superfamily
APMBIKAL_01421 1.3e-154 yitH K Acetyltransferase (GNAT) domain
APMBIKAL_01422 8.6e-70 yjcF S Acetyltransferase (GNAT) domain
APMBIKAL_01423 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
APMBIKAL_01424 9.5e-54 yajQ S Belongs to the UPF0234 family
APMBIKAL_01425 6.9e-161 cvfB S protein conserved in bacteria
APMBIKAL_01426 2.5e-93
APMBIKAL_01427 1.4e-170
APMBIKAL_01428 7.6e-97 S Sporulation delaying protein SdpA
APMBIKAL_01429 1.5e-58 K Transcriptional regulator PadR-like family
APMBIKAL_01430 2.9e-94
APMBIKAL_01431 1.4e-44 yitR S Domain of unknown function (DUF3784)
APMBIKAL_01432 4.6e-307 nprB 3.4.24.28 E Peptidase M4
APMBIKAL_01433 1.4e-158 yitS S protein conserved in bacteria
APMBIKAL_01434 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
APMBIKAL_01435 2.9e-73 ipi S Intracellular proteinase inhibitor
APMBIKAL_01436 1.2e-17 S Protein of unknown function (DUF3813)
APMBIKAL_01438 2.1e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
APMBIKAL_01439 1e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
APMBIKAL_01440 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
APMBIKAL_01441 1.5e-22 pilT S Proteolipid membrane potential modulator
APMBIKAL_01442 1.9e-267 yitY C D-arabinono-1,4-lactone oxidase
APMBIKAL_01443 1.7e-88 norB G Major Facilitator Superfamily
APMBIKAL_01444 4.3e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
APMBIKAL_01445 2e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
APMBIKAL_01446 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
APMBIKAL_01447 6.4e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
APMBIKAL_01448 1.1e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
APMBIKAL_01449 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
APMBIKAL_01450 1.2e-174 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
APMBIKAL_01451 9.5e-28 yjzC S YjzC-like protein
APMBIKAL_01452 2.3e-16 yjzD S Protein of unknown function (DUF2929)
APMBIKAL_01453 3.1e-141 yjaU I carboxylic ester hydrolase activity
APMBIKAL_01454 1.5e-100 yjaV
APMBIKAL_01455 2.5e-183 med S Transcriptional activator protein med
APMBIKAL_01456 7.3e-26 comZ S ComZ
APMBIKAL_01457 2.4e-20 yjzB
APMBIKAL_01458 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
APMBIKAL_01459 6.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
APMBIKAL_01460 7.3e-149 yjaZ O Zn-dependent protease
APMBIKAL_01461 3.9e-184 appD P Belongs to the ABC transporter superfamily
APMBIKAL_01462 2.7e-185 appF E Belongs to the ABC transporter superfamily
APMBIKAL_01463 2.4e-287 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
APMBIKAL_01464 7.7e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APMBIKAL_01465 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APMBIKAL_01466 5.5e-146 yjbA S Belongs to the UPF0736 family
APMBIKAL_01467 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
APMBIKAL_01468 9.4e-308 oppA E ABC transporter substrate-binding protein
APMBIKAL_01469 8.7e-165 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APMBIKAL_01470 5e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APMBIKAL_01471 6.8e-198 oppD P Belongs to the ABC transporter superfamily
APMBIKAL_01472 5.5e-172 oppF E Belongs to the ABC transporter superfamily
APMBIKAL_01473 8.3e-205 yjbB EGP Major Facilitator Superfamily
APMBIKAL_01474 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APMBIKAL_01475 2.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
APMBIKAL_01476 2.3e-111 yjbE P Integral membrane protein TerC family
APMBIKAL_01477 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
APMBIKAL_01478 2e-219 yjbF S Competence protein
APMBIKAL_01479 0.0 pepF E oligoendopeptidase F
APMBIKAL_01480 1.8e-20
APMBIKAL_01481 1.2e-168 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
APMBIKAL_01482 3.7e-72 yjbI S Bacterial-like globin
APMBIKAL_01483 3.1e-85 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
APMBIKAL_01484 1.2e-100 yjbK S protein conserved in bacteria
APMBIKAL_01485 7.1e-62 yjbL S Belongs to the UPF0738 family
APMBIKAL_01486 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
APMBIKAL_01487 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
APMBIKAL_01488 1.2e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
APMBIKAL_01489 5.1e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
APMBIKAL_01490 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
APMBIKAL_01491 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
APMBIKAL_01492 1.4e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
APMBIKAL_01493 9.8e-216 thiO 1.4.3.19 E Glycine oxidase
APMBIKAL_01494 2.6e-29 thiS H thiamine diphosphate biosynthetic process
APMBIKAL_01495 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
APMBIKAL_01496 2.3e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
APMBIKAL_01497 2e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
APMBIKAL_01498 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
APMBIKAL_01499 5.9e-54 yjbX S Spore coat protein
APMBIKAL_01500 5.2e-83 cotZ S Spore coat protein
APMBIKAL_01501 7.6e-96 cotY S Spore coat protein Z
APMBIKAL_01502 6.4e-77 cotX S Spore Coat Protein X and V domain
APMBIKAL_01503 8.5e-32 cotW
APMBIKAL_01504 2.3e-55 cotV S Spore Coat Protein X and V domain
APMBIKAL_01505 4.3e-56 yjcA S Protein of unknown function (DUF1360)
APMBIKAL_01508 2.9e-38 spoVIF S Stage VI sporulation protein F
APMBIKAL_01509 0.0 yjcD 3.6.4.12 L DNA helicase
APMBIKAL_01510 1.7e-38
APMBIKAL_01511 5.1e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APMBIKAL_01512 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
APMBIKAL_01513 2.6e-137 yjcH P COG2382 Enterochelin esterase and related enzymes
APMBIKAL_01514 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
APMBIKAL_01515 1.9e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
APMBIKAL_01516 1.7e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
APMBIKAL_01517 7e-212 yjcL S Protein of unknown function (DUF819)
APMBIKAL_01519 3.4e-10
APMBIKAL_01520 1.7e-40
APMBIKAL_01521 2.9e-244 M nucleic acid phosphodiester bond hydrolysis
APMBIKAL_01523 3.7e-30 KLT Protein tyrosine kinase
APMBIKAL_01524 4.3e-11 S YolD-like protein
APMBIKAL_01525 1.2e-35
APMBIKAL_01526 9e-19
APMBIKAL_01528 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
APMBIKAL_01529 2e-140 IQ Enoyl-(Acyl carrier protein) reductase
APMBIKAL_01531 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
APMBIKAL_01532 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
APMBIKAL_01533 8.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
APMBIKAL_01534 4.5e-49 yjdF S Protein of unknown function (DUF2992)
APMBIKAL_01535 6.9e-92 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
APMBIKAL_01537 2.6e-80 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
APMBIKAL_01538 4.2e-29 S Domain of unknown function (DUF4177)
APMBIKAL_01539 2.3e-51 yjdJ S Domain of unknown function (DUF4306)
APMBIKAL_01540 7.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
APMBIKAL_01542 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
APMBIKAL_01543 2.1e-82 S Protein of unknown function (DUF2690)
APMBIKAL_01544 2.3e-20 yjfB S Putative motility protein
APMBIKAL_01545 1.4e-167 yjfC O Predicted Zn-dependent protease (DUF2268)
APMBIKAL_01546 1.2e-45 T PhoQ Sensor
APMBIKAL_01547 9.9e-103 yjgB S Domain of unknown function (DUF4309)
APMBIKAL_01548 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
APMBIKAL_01549 4.3e-95 yjgD S Protein of unknown function (DUF1641)
APMBIKAL_01550 8.7e-07 S Domain of unknown function (DUF4352)
APMBIKAL_01551 1.3e-116 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
APMBIKAL_01553 2.3e-223 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
APMBIKAL_01554 8.5e-218 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
APMBIKAL_01555 8.2e-30
APMBIKAL_01556 3.1e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
APMBIKAL_01557 3.3e-122 ybbM S transport system, permease component
APMBIKAL_01558 1.8e-133 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
APMBIKAL_01559 7.4e-175 yjlA EG Putative multidrug resistance efflux transporter
APMBIKAL_01560 1.6e-88 yjlB S Cupin domain
APMBIKAL_01561 7.1e-66 yjlC S Protein of unknown function (DUF1641)
APMBIKAL_01562 6.5e-218 yjlD 1.6.99.3 C NADH dehydrogenase
APMBIKAL_01563 8.7e-278 uxaC 5.3.1.12 G glucuronate isomerase
APMBIKAL_01564 4.6e-247 yjmB G symporter YjmB
APMBIKAL_01565 2.7e-188 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
APMBIKAL_01566 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
APMBIKAL_01567 2.3e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
APMBIKAL_01568 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
APMBIKAL_01569 1.1e-226 exuT G Sugar (and other) transporter
APMBIKAL_01570 3.1e-184 exuR K transcriptional
APMBIKAL_01571 1.1e-280 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
APMBIKAL_01572 4.9e-287 uxaA 4.2.1.7, 4.4.1.24 G Altronate
APMBIKAL_01573 4.3e-130 MA20_18170 S membrane transporter protein
APMBIKAL_01574 2.3e-78 yjoA S DinB family
APMBIKAL_01575 3.3e-244 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
APMBIKAL_01576 1e-212 S response regulator aspartate phosphatase
APMBIKAL_01578 5.3e-40 S YCII-related domain
APMBIKAL_01579 9.4e-167 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
APMBIKAL_01580 6.1e-61 yjqA S Bacterial PH domain
APMBIKAL_01581 1.3e-110 yjqB S Pfam:DUF867
APMBIKAL_01582 1.7e-159 ydbD P Catalase
APMBIKAL_01583 1.6e-111 xkdA E IrrE N-terminal-like domain
APMBIKAL_01584 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
APMBIKAL_01586 2.3e-156 xkdB K sequence-specific DNA binding
APMBIKAL_01587 1.2e-117 xkdC L Bacterial dnaA protein
APMBIKAL_01590 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
APMBIKAL_01591 7.7e-83 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
APMBIKAL_01592 5.3e-139 xtmA L phage terminase small subunit
APMBIKAL_01593 6.2e-254 xtmB S phage terminase, large subunit
APMBIKAL_01594 3.5e-285 yqbA S portal protein
APMBIKAL_01595 4.1e-134 yqbD 2.1.1.72 L Putative phage serine protease XkdF
APMBIKAL_01596 5.8e-169 xkdG S Phage capsid family
APMBIKAL_01597 5.6e-62 yqbG S Protein of unknown function (DUF3199)
APMBIKAL_01598 8.7e-65 yqbH S Domain of unknown function (DUF3599)
APMBIKAL_01599 9.9e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
APMBIKAL_01600 3.2e-77 xkdJ
APMBIKAL_01601 2.5e-256 xkdK S Phage tail sheath C-terminal domain
APMBIKAL_01602 6.1e-76 xkdM S Phage tail tube protein
APMBIKAL_01603 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
APMBIKAL_01604 0.0 xkdO L Transglycosylase SLT domain
APMBIKAL_01605 3.9e-119 xkdP S Lysin motif
APMBIKAL_01606 6.2e-182 yqbQ 3.2.1.96 G NLP P60 protein
APMBIKAL_01607 2.1e-39 xkdR S Protein of unknown function (DUF2577)
APMBIKAL_01608 1.6e-70 xkdS S Protein of unknown function (DUF2634)
APMBIKAL_01609 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
APMBIKAL_01610 1.3e-102 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
APMBIKAL_01611 1.5e-40
APMBIKAL_01612 0.0
APMBIKAL_01613 1.6e-52 xkdW S XkdW protein
APMBIKAL_01614 1.4e-22 xkdX
APMBIKAL_01615 1.5e-152 xepA
APMBIKAL_01616 2.8e-39 xhlA S Haemolysin XhlA
APMBIKAL_01617 9.3e-40 xhlB S SPP1 phage holin
APMBIKAL_01618 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
APMBIKAL_01619 6.7e-23 spoIISB S Stage II sporulation protein SB
APMBIKAL_01620 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
APMBIKAL_01621 5.8e-175 pit P phosphate transporter
APMBIKAL_01622 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
APMBIKAL_01623 9.8e-239 steT E amino acid
APMBIKAL_01624 9.4e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
APMBIKAL_01625 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
APMBIKAL_01626 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
APMBIKAL_01628 8.4e-209 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
APMBIKAL_01629 4.5e-133 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
APMBIKAL_01630 1.9e-152 dppA E D-aminopeptidase
APMBIKAL_01631 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APMBIKAL_01632 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APMBIKAL_01633 3.9e-187 dppD P Belongs to the ABC transporter superfamily
APMBIKAL_01634 0.0 dppE E ABC transporter substrate-binding protein
APMBIKAL_01636 5.4e-175 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
APMBIKAL_01637 3.7e-199 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
APMBIKAL_01638 3.2e-161 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
APMBIKAL_01639 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
APMBIKAL_01640 1.5e-202 pgl 3.1.1.31 G 6-phosphogluconolactonase
APMBIKAL_01641 1.2e-160 ykgA E Amidinotransferase
APMBIKAL_01642 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
APMBIKAL_01643 2.5e-225 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
APMBIKAL_01644 7.2e-09
APMBIKAL_01645 3.5e-129 ykjA S Protein of unknown function (DUF421)
APMBIKAL_01646 1.5e-97 ykkA S Protein of unknown function (DUF664)
APMBIKAL_01647 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
APMBIKAL_01648 1.3e-54 ykkC P Multidrug resistance protein
APMBIKAL_01649 1.6e-49 ykkD P Multidrug resistance protein
APMBIKAL_01650 8.6e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
APMBIKAL_01651 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
APMBIKAL_01652 1.2e-225 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
APMBIKAL_01653 4.8e-70 ohrA O Organic hydroperoxide resistance protein
APMBIKAL_01654 3.9e-75 ohrR K COG1846 Transcriptional regulators
APMBIKAL_01655 8.4e-72 ohrB O Organic hydroperoxide resistance protein
APMBIKAL_01656 5.5e-83 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
APMBIKAL_01657 6.5e-100 5.4.2.11 G Belongs to the phosphoglycerate mutase family
APMBIKAL_01658 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
APMBIKAL_01659 5e-176 isp O Belongs to the peptidase S8 family
APMBIKAL_01660 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
APMBIKAL_01661 1.5e-135 ykoC P Cobalt transport protein
APMBIKAL_01662 6.3e-304 P ABC transporter, ATP-binding protein
APMBIKAL_01663 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
APMBIKAL_01664 4.3e-109 ykoF S YKOF-related Family
APMBIKAL_01665 2.7e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APMBIKAL_01666 8.3e-241 ykoH 2.7.13.3 T Histidine kinase
APMBIKAL_01667 8.1e-112 ykoI S Peptidase propeptide and YPEB domain
APMBIKAL_01668 6.3e-85 ykoJ S Peptidase propeptide and YPEB domain
APMBIKAL_01671 2.2e-222 mgtE P Acts as a magnesium transporter
APMBIKAL_01672 1.4e-53 tnrA K transcriptional
APMBIKAL_01673 1.3e-17
APMBIKAL_01674 3.4e-25 ykoL
APMBIKAL_01675 1.9e-80 mhqR K transcriptional
APMBIKAL_01676 5.6e-219 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
APMBIKAL_01677 3.7e-99 ykoP G polysaccharide deacetylase
APMBIKAL_01678 6e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
APMBIKAL_01679 0.0 ykoS
APMBIKAL_01680 8.2e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
APMBIKAL_01681 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
APMBIKAL_01682 2.1e-160 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
APMBIKAL_01683 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
APMBIKAL_01684 3.5e-109 ykoX S membrane-associated protein
APMBIKAL_01685 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
APMBIKAL_01686 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APMBIKAL_01687 1.7e-114 rsgI S Anti-sigma factor N-terminus
APMBIKAL_01688 1.9e-26 sspD S small acid-soluble spore protein
APMBIKAL_01689 5.6e-124 ykrK S Domain of unknown function (DUF1836)
APMBIKAL_01690 3.5e-155 htpX O Belongs to the peptidase M48B family
APMBIKAL_01691 2.2e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
APMBIKAL_01692 1.2e-10 ydfR S Protein of unknown function (DUF421)
APMBIKAL_01693 4.5e-22 ykzE
APMBIKAL_01694 2.7e-188 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
APMBIKAL_01695 0.0 kinE 2.7.13.3 T Histidine kinase
APMBIKAL_01696 5e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
APMBIKAL_01698 1.4e-195 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
APMBIKAL_01699 2.4e-228 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
APMBIKAL_01700 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
APMBIKAL_01701 3.4e-230 mtnE 2.6.1.83 E Aminotransferase
APMBIKAL_01702 1.3e-229 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
APMBIKAL_01703 8.3e-136 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
APMBIKAL_01704 4.7e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
APMBIKAL_01705 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
APMBIKAL_01706 2.2e-51 XK27_09985 S Protein of unknown function (DUF1232)
APMBIKAL_01707 6.4e-09 S Spo0E like sporulation regulatory protein
APMBIKAL_01708 4e-64 eag
APMBIKAL_01709 2.1e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
APMBIKAL_01710 1.3e-75 ykvE K transcriptional
APMBIKAL_01711 2.5e-125 motB N Flagellar motor protein
APMBIKAL_01712 1e-137 motA N flagellar motor
APMBIKAL_01713 0.0 clpE O Belongs to the ClpA ClpB family
APMBIKAL_01714 1.8e-179 ykvI S membrane
APMBIKAL_01715 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
APMBIKAL_01716 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
APMBIKAL_01717 6.4e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
APMBIKAL_01718 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
APMBIKAL_01719 9.9e-61 ykvN K Transcriptional regulator
APMBIKAL_01720 5.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
APMBIKAL_01721 2.5e-233 ykvP 3.5.1.28 M Glycosyl transferases group 1
APMBIKAL_01722 1.2e-35 3.5.1.104 M LysM domain
APMBIKAL_01723 2.8e-163 G Glycosyl hydrolases family 18
APMBIKAL_01724 2.8e-45 ykvR S Protein of unknown function (DUF3219)
APMBIKAL_01725 6e-25 ykvS S protein conserved in bacteria
APMBIKAL_01726 2.8e-28
APMBIKAL_01727 3.1e-102 ykvT 3.5.1.28 M Cell Wall Hydrolase
APMBIKAL_01728 3.8e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APMBIKAL_01729 9.2e-89 stoA CO thiol-disulfide
APMBIKAL_01730 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
APMBIKAL_01731 1e-09
APMBIKAL_01732 1.3e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
APMBIKAL_01733 5.4e-178 ykvZ 5.1.1.1 K Transcriptional regulator
APMBIKAL_01735 1.7e-127 glcT K antiterminator
APMBIKAL_01736 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APMBIKAL_01737 1e-38 ptsH G phosphocarrier protein HPr
APMBIKAL_01738 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
APMBIKAL_01739 7.2e-39 splA S Transcriptional regulator
APMBIKAL_01740 6.3e-201 splB 4.1.99.14 L Spore photoproduct lyase
APMBIKAL_01741 1.9e-129 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APMBIKAL_01742 1.1e-262 mcpC NT chemotaxis protein
APMBIKAL_01743 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
APMBIKAL_01744 8e-124 ykwD J protein with SCP PR1 domains
APMBIKAL_01745 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
APMBIKAL_01746 0.0 pilS 2.7.13.3 T Histidine kinase
APMBIKAL_01747 8.8e-223 patA 2.6.1.1 E Aminotransferase
APMBIKAL_01748 4.9e-15
APMBIKAL_01749 1.6e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
APMBIKAL_01750 1.7e-84 ykyB S YkyB-like protein
APMBIKAL_01751 4.5e-236 ykuC EGP Major facilitator Superfamily
APMBIKAL_01752 1.8e-87 ykuD S protein conserved in bacteria
APMBIKAL_01753 9.4e-166 ykuE S Metallophosphoesterase
APMBIKAL_01754 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APMBIKAL_01755 5.2e-234 ykuI T Diguanylate phosphodiesterase
APMBIKAL_01756 3.9e-37 ykuJ S protein conserved in bacteria
APMBIKAL_01757 4.9e-93 ykuK S Ribonuclease H-like
APMBIKAL_01758 3.9e-27 ykzF S Antirepressor AbbA
APMBIKAL_01759 1.6e-76 ykuL S CBS domain
APMBIKAL_01760 3.5e-168 ccpC K Transcriptional regulator
APMBIKAL_01761 2.4e-86 fld C Flavodoxin domain
APMBIKAL_01762 1.8e-175 ykuO
APMBIKAL_01763 6.2e-76 fld C Flavodoxin
APMBIKAL_01764 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
APMBIKAL_01765 4.9e-215 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
APMBIKAL_01766 9e-37 ykuS S Belongs to the UPF0180 family
APMBIKAL_01767 8.8e-142 ykuT M Mechanosensitive ion channel
APMBIKAL_01768 3.9e-101 ykuU O Alkyl hydroperoxide reductase
APMBIKAL_01769 4.1e-80 ykuV CO thiol-disulfide
APMBIKAL_01770 5.8e-95 rok K Repressor of ComK
APMBIKAL_01771 3.5e-145 yknT
APMBIKAL_01772 3.9e-110 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
APMBIKAL_01773 2.2e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
APMBIKAL_01774 8.4e-243 moeA 2.10.1.1 H molybdopterin
APMBIKAL_01775 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
APMBIKAL_01776 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
APMBIKAL_01777 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
APMBIKAL_01778 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
APMBIKAL_01779 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
APMBIKAL_01780 1.4e-114 yknW S Yip1 domain
APMBIKAL_01781 5.6e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APMBIKAL_01782 2.5e-124 macB V ABC transporter, ATP-binding protein
APMBIKAL_01783 6.2e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
APMBIKAL_01784 3.1e-136 fruR K Transcriptional regulator
APMBIKAL_01785 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
APMBIKAL_01786 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
APMBIKAL_01787 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
APMBIKAL_01788 8.1e-39 ykoA
APMBIKAL_01789 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
APMBIKAL_01790 1.1e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
APMBIKAL_01791 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
APMBIKAL_01792 1.1e-12 S Uncharacterized protein YkpC
APMBIKAL_01793 7.7e-183 mreB D Rod-share determining protein MreBH
APMBIKAL_01794 7.3e-43 abrB K of stationary sporulation gene expression
APMBIKAL_01795 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
APMBIKAL_01796 3.8e-156 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
APMBIKAL_01797 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
APMBIKAL_01798 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
APMBIKAL_01799 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
APMBIKAL_01800 8.2e-31 ykzG S Belongs to the UPF0356 family
APMBIKAL_01801 5.5e-147 ykrA S hydrolases of the HAD superfamily
APMBIKAL_01802 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
APMBIKAL_01804 1.3e-106 recN L Putative cell-wall binding lipoprotein
APMBIKAL_01805 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
APMBIKAL_01806 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
APMBIKAL_01807 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
APMBIKAL_01808 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
APMBIKAL_01809 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
APMBIKAL_01810 3.5e-277 speA 4.1.1.19 E Arginine
APMBIKAL_01811 1.7e-41 yktA S Belongs to the UPF0223 family
APMBIKAL_01812 4.6e-117 yktB S Belongs to the UPF0637 family
APMBIKAL_01813 7.1e-26 ykzI
APMBIKAL_01814 4.3e-149 suhB 3.1.3.25 G Inositol monophosphatase
APMBIKAL_01815 1.1e-75 ykzC S Acetyltransferase (GNAT) family
APMBIKAL_01816 1e-170 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
APMBIKAL_01817 1.1e-292 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
APMBIKAL_01818 0.0 ylaA
APMBIKAL_01819 3e-41 ylaB
APMBIKAL_01820 2.5e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
APMBIKAL_01821 7.1e-12 sigC S Putative zinc-finger
APMBIKAL_01822 1.2e-37 ylaE
APMBIKAL_01823 1.1e-21 S Family of unknown function (DUF5325)
APMBIKAL_01824 0.0 typA T GTP-binding protein TypA
APMBIKAL_01825 4.2e-47 ylaH S YlaH-like protein
APMBIKAL_01826 2.5e-32 ylaI S protein conserved in bacteria
APMBIKAL_01827 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
APMBIKAL_01828 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
APMBIKAL_01829 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
APMBIKAL_01830 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
APMBIKAL_01831 8.7e-44 ylaN S Belongs to the UPF0358 family
APMBIKAL_01832 9.4e-212 ftsW D Belongs to the SEDS family
APMBIKAL_01833 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
APMBIKAL_01834 3.2e-164 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
APMBIKAL_01835 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
APMBIKAL_01836 6.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
APMBIKAL_01837 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
APMBIKAL_01838 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
APMBIKAL_01839 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
APMBIKAL_01840 2.8e-165 ctaG S cytochrome c oxidase
APMBIKAL_01841 7e-62 ylbA S YugN-like family
APMBIKAL_01842 2.6e-74 ylbB T COG0517 FOG CBS domain
APMBIKAL_01843 9.6e-200 ylbC S protein with SCP PR1 domains
APMBIKAL_01844 5.9e-62 ylbD S Putative coat protein
APMBIKAL_01845 6.7e-37 ylbE S YlbE-like protein
APMBIKAL_01846 1.8e-75 ylbF S Belongs to the UPF0342 family
APMBIKAL_01847 3.7e-38 ylbG S UPF0298 protein
APMBIKAL_01848 7.8e-97 rsmD 2.1.1.171 L Methyltransferase
APMBIKAL_01849 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
APMBIKAL_01850 1.1e-220 ylbJ S Sporulation integral membrane protein YlbJ
APMBIKAL_01851 1.3e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
APMBIKAL_01852 2.2e-185 ylbL T Belongs to the peptidase S16 family
APMBIKAL_01853 4.3e-228 ylbM S Belongs to the UPF0348 family
APMBIKAL_01855 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
APMBIKAL_01856 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
APMBIKAL_01857 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
APMBIKAL_01858 4e-89 ylbP K n-acetyltransferase
APMBIKAL_01859 6.8e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
APMBIKAL_01860 2.7e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
APMBIKAL_01861 2.9e-78 mraZ K Belongs to the MraZ family
APMBIKAL_01862 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
APMBIKAL_01863 3.7e-44 ftsL D Essential cell division protein
APMBIKAL_01864 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
APMBIKAL_01865 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
APMBIKAL_01866 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
APMBIKAL_01867 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
APMBIKAL_01868 1.4e-253 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
APMBIKAL_01869 5.7e-186 spoVE D Belongs to the SEDS family
APMBIKAL_01870 1.1e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
APMBIKAL_01871 5.3e-167 murB 1.3.1.98 M cell wall formation
APMBIKAL_01872 1e-137 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
APMBIKAL_01873 4.1e-103 ylxW S protein conserved in bacteria
APMBIKAL_01874 1.8e-91 ylxX S protein conserved in bacteria
APMBIKAL_01875 6.2e-58 sbp S small basic protein
APMBIKAL_01876 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
APMBIKAL_01877 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
APMBIKAL_01878 0.0 bpr O COG1404 Subtilisin-like serine proteases
APMBIKAL_01880 6.8e-170 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
APMBIKAL_01881 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APMBIKAL_01882 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APMBIKAL_01883 3.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
APMBIKAL_01884 2.6e-252 argE 3.5.1.16 E Acetylornithine deacetylase
APMBIKAL_01885 2.4e-37 ylmC S sporulation protein
APMBIKAL_01886 8.6e-156 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
APMBIKAL_01887 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
APMBIKAL_01888 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
APMBIKAL_01889 1.3e-39 yggT S membrane
APMBIKAL_01890 2e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
APMBIKAL_01891 2.6e-67 divIVA D Cell division initiation protein
APMBIKAL_01892 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
APMBIKAL_01893 1.3e-63 dksA T COG1734 DnaK suppressor protein
APMBIKAL_01894 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
APMBIKAL_01895 1.2e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
APMBIKAL_01896 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
APMBIKAL_01897 5.4e-229 pyrP F Xanthine uracil
APMBIKAL_01898 3.4e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
APMBIKAL_01899 4.1e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
APMBIKAL_01900 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
APMBIKAL_01901 0.0 carB 6.3.5.5 F Belongs to the CarB family
APMBIKAL_01902 1.4e-144 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
APMBIKAL_01903 6.6e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
APMBIKAL_01904 2.3e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
APMBIKAL_01905 8e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
APMBIKAL_01906 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
APMBIKAL_01907 1.8e-179 cysP P phosphate transporter
APMBIKAL_01908 5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
APMBIKAL_01909 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
APMBIKAL_01910 2e-143 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
APMBIKAL_01911 1.3e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
APMBIKAL_01912 1.6e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
APMBIKAL_01913 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
APMBIKAL_01914 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
APMBIKAL_01915 2.4e-156 yloC S stress-induced protein
APMBIKAL_01916 1.5e-40 ylzA S Belongs to the UPF0296 family
APMBIKAL_01917 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
APMBIKAL_01918 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
APMBIKAL_01919 8.2e-224 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
APMBIKAL_01920 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
APMBIKAL_01921 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
APMBIKAL_01922 5.2e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
APMBIKAL_01923 3.2e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
APMBIKAL_01924 5.3e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
APMBIKAL_01925 1.8e-139 stp 3.1.3.16 T phosphatase
APMBIKAL_01926 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
APMBIKAL_01927 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
APMBIKAL_01928 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
APMBIKAL_01929 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
APMBIKAL_01930 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
APMBIKAL_01931 5.5e-59 asp S protein conserved in bacteria
APMBIKAL_01932 1.4e-298 yloV S kinase related to dihydroxyacetone kinase
APMBIKAL_01933 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
APMBIKAL_01934 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
APMBIKAL_01935 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
APMBIKAL_01936 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
APMBIKAL_01937 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
APMBIKAL_01938 3.5e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
APMBIKAL_01939 6.1e-129 IQ reductase
APMBIKAL_01940 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
APMBIKAL_01941 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
APMBIKAL_01942 0.0 smc D Required for chromosome condensation and partitioning
APMBIKAL_01943 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
APMBIKAL_01944 1.1e-86
APMBIKAL_01945 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
APMBIKAL_01946 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
APMBIKAL_01947 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
APMBIKAL_01948 4.5e-36 ylqC S Belongs to the UPF0109 family
APMBIKAL_01949 1.4e-60 ylqD S YlqD protein
APMBIKAL_01950 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
APMBIKAL_01951 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
APMBIKAL_01952 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
APMBIKAL_01953 4.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
APMBIKAL_01954 6.9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
APMBIKAL_01955 3.7e-286 ylqG
APMBIKAL_01956 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
APMBIKAL_01957 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
APMBIKAL_01958 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
APMBIKAL_01959 5e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
APMBIKAL_01960 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
APMBIKAL_01961 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
APMBIKAL_01962 2.5e-169 xerC L tyrosine recombinase XerC
APMBIKAL_01963 1.3e-91 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
APMBIKAL_01964 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
APMBIKAL_01965 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
APMBIKAL_01966 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
APMBIKAL_01967 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
APMBIKAL_01968 1.9e-31 fliE N Flagellar hook-basal body
APMBIKAL_01969 2.4e-255 fliF N The M ring may be actively involved in energy transduction
APMBIKAL_01970 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
APMBIKAL_01971 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
APMBIKAL_01972 2.1e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
APMBIKAL_01973 1.5e-69 fliJ N Flagellar biosynthesis chaperone
APMBIKAL_01974 1.3e-36 ylxF S MgtE intracellular N domain
APMBIKAL_01975 4.3e-219 fliK N Flagellar hook-length control protein
APMBIKAL_01976 1.7e-72 flgD N Flagellar basal body rod modification protein
APMBIKAL_01977 8.2e-140 flgG N Flagellar basal body rod
APMBIKAL_01978 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
APMBIKAL_01979 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
APMBIKAL_01980 5.5e-174 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
APMBIKAL_01981 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
APMBIKAL_01982 4.6e-96 fliZ N Flagellar biosynthesis protein, FliO
APMBIKAL_01983 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
APMBIKAL_01984 2.2e-36 fliQ N Role in flagellar biosynthesis
APMBIKAL_01985 3.6e-132 fliR N Flagellar biosynthetic protein FliR
APMBIKAL_01986 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
APMBIKAL_01987 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
APMBIKAL_01988 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
APMBIKAL_01989 1.7e-157 flhG D Belongs to the ParA family
APMBIKAL_01990 1.7e-196 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
APMBIKAL_01991 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
APMBIKAL_01992 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
APMBIKAL_01993 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
APMBIKAL_01994 4.3e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
APMBIKAL_01995 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APMBIKAL_01996 5.3e-76 ylxL
APMBIKAL_01997 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
APMBIKAL_01998 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
APMBIKAL_01999 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
APMBIKAL_02000 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
APMBIKAL_02001 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
APMBIKAL_02002 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
APMBIKAL_02003 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
APMBIKAL_02004 7.7e-233 rasP M zinc metalloprotease
APMBIKAL_02005 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
APMBIKAL_02006 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
APMBIKAL_02007 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
APMBIKAL_02008 1.1e-203 nusA K Participates in both transcription termination and antitermination
APMBIKAL_02009 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
APMBIKAL_02010 3.1e-47 ylxQ J ribosomal protein
APMBIKAL_02011 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
APMBIKAL_02012 3.9e-44 ylxP S protein conserved in bacteria
APMBIKAL_02013 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
APMBIKAL_02014 1.2e-169 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
APMBIKAL_02015 6.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
APMBIKAL_02016 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
APMBIKAL_02017 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
APMBIKAL_02018 4e-181 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
APMBIKAL_02019 4.4e-233 pepR S Belongs to the peptidase M16 family
APMBIKAL_02020 2.6e-42 ymxH S YlmC YmxH family
APMBIKAL_02021 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
APMBIKAL_02022 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
APMBIKAL_02023 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
APMBIKAL_02024 5.9e-222 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
APMBIKAL_02025 4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
APMBIKAL_02026 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
APMBIKAL_02027 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
APMBIKAL_02028 2.9e-31 S YlzJ-like protein
APMBIKAL_02029 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
APMBIKAL_02030 1.4e-133 ymfC K Transcriptional regulator
APMBIKAL_02031 3.8e-205 ymfD EGP Major facilitator Superfamily
APMBIKAL_02032 1.3e-232 ymfF S Peptidase M16
APMBIKAL_02033 2.3e-240 ymfH S zinc protease
APMBIKAL_02034 2.7e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
APMBIKAL_02035 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
APMBIKAL_02036 2.7e-143 ymfK S Protein of unknown function (DUF3388)
APMBIKAL_02037 1.8e-122 ymfM S protein conserved in bacteria
APMBIKAL_02038 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
APMBIKAL_02039 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
APMBIKAL_02040 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
APMBIKAL_02041 2e-211 pbpX V Beta-lactamase
APMBIKAL_02042 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
APMBIKAL_02043 7.1e-152 ymdB S protein conserved in bacteria
APMBIKAL_02044 1.2e-36 spoVS S Stage V sporulation protein S
APMBIKAL_02045 3.6e-196 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
APMBIKAL_02046 7.2e-217 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
APMBIKAL_02047 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
APMBIKAL_02048 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
APMBIKAL_02049 2.2e-88 cotE S Spore coat protein
APMBIKAL_02050 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
APMBIKAL_02051 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
APMBIKAL_02052 5.1e-70 S Regulatory protein YrvL
APMBIKAL_02054 1.2e-97 ymcC S Membrane
APMBIKAL_02055 2.9e-108 pksA K Transcriptional regulator
APMBIKAL_02056 3.7e-125 pksB 3.1.2.6 S Polyketide biosynthesis
APMBIKAL_02057 2.2e-162 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
APMBIKAL_02059 6e-185 pksD Q Acyl transferase domain
APMBIKAL_02060 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
APMBIKAL_02061 1.4e-37 acpK IQ Phosphopantetheine attachment site
APMBIKAL_02062 8.7e-237 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
APMBIKAL_02063 1.5e-244 pksG 2.3.3.10 I synthase
APMBIKAL_02064 1.3e-142 pksH 4.2.1.18 I enoyl-CoA hydratase
APMBIKAL_02065 1e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
APMBIKAL_02066 0.0 rhiB IQ polyketide synthase
APMBIKAL_02067 0.0 pfaA Q Polyketide synthase of type I
APMBIKAL_02068 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
APMBIKAL_02069 0.0 dhbF IQ polyketide synthase
APMBIKAL_02070 0.0 pks13 HQ Beta-ketoacyl synthase
APMBIKAL_02071 2.2e-232 cypA C Cytochrome P450
APMBIKAL_02072 4.4e-61 ymzB
APMBIKAL_02073 2.3e-161 ymaE S Metallo-beta-lactamase superfamily
APMBIKAL_02074 1.2e-249 aprX O Belongs to the peptidase S8 family
APMBIKAL_02075 1.9e-07 K Transcriptional regulator
APMBIKAL_02076 2.1e-126 ymaC S Replication protein
APMBIKAL_02077 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
APMBIKAL_02078 8.9e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
APMBIKAL_02079 5.4e-50 ebrA P Small Multidrug Resistance protein
APMBIKAL_02081 2.1e-46 ymaF S YmaF family
APMBIKAL_02082 4.6e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
APMBIKAL_02083 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
APMBIKAL_02084 3.7e-23
APMBIKAL_02085 4.5e-22 ymzA
APMBIKAL_02086 9.6e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
APMBIKAL_02087 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APMBIKAL_02088 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APMBIKAL_02089 2e-109 ymaB
APMBIKAL_02090 1.8e-112 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
APMBIKAL_02091 2.8e-98 spoVK O stage V sporulation protein K
APMBIKAL_02093 5.8e-81 yhbS S family acetyltransferase
APMBIKAL_02094 8.7e-106 yokF 3.1.31.1 L RNA catabolic process
APMBIKAL_02095 4.7e-33
APMBIKAL_02096 8.2e-67 G SMI1-KNR4 cell-wall
APMBIKAL_02097 2.5e-133 V HNH endonuclease
APMBIKAL_02098 7.8e-173 yobL S Bacterial EndoU nuclease
APMBIKAL_02099 4.2e-80 S SMI1-KNR4 cell-wall
APMBIKAL_02100 3.6e-10 S Domain of unknown function (DUF4879)
APMBIKAL_02102 1.3e-37
APMBIKAL_02104 1.3e-51 S YolD-like protein
APMBIKAL_02105 1.2e-233 S impB/mucB/samB family C-terminal domain
APMBIKAL_02107 9.4e-190 S aspartate phosphatase
APMBIKAL_02108 9.2e-37 S Bacteriophage holin
APMBIKAL_02110 3.5e-74 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
APMBIKAL_02111 1.5e-27
APMBIKAL_02112 2.8e-52
APMBIKAL_02113 8.4e-298 S Pfam Transposase IS66
APMBIKAL_02114 2.5e-85 S Phage tail protein
APMBIKAL_02115 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
APMBIKAL_02116 1.1e-105
APMBIKAL_02118 1.2e-122 xerH L Belongs to the 'phage' integrase family
APMBIKAL_02119 1.3e-62
APMBIKAL_02120 2.2e-82
APMBIKAL_02121 5.4e-08 xkdX
APMBIKAL_02122 1.5e-08
APMBIKAL_02123 1.5e-64 S Domain of unknown function (DUF2479)
APMBIKAL_02124 4.5e-53
APMBIKAL_02127 3.2e-59
APMBIKAL_02128 1.3e-72
APMBIKAL_02129 8.8e-79
APMBIKAL_02130 1.8e-68
APMBIKAL_02133 3.3e-70
APMBIKAL_02135 1.6e-35
APMBIKAL_02136 4e-18
APMBIKAL_02137 9.6e-109
APMBIKAL_02138 4.9e-17
APMBIKAL_02143 7.2e-228 S hydrolase activity
APMBIKAL_02145 2.1e-34 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
APMBIKAL_02146 5.8e-94
APMBIKAL_02147 6.5e-16 L GIY-YIG type nucleases (URI domain)
APMBIKAL_02148 0.0 S RNA-directed RNA polymerase activity
APMBIKAL_02151 3.6e-203
APMBIKAL_02152 1.8e-100 S DNA binding
APMBIKAL_02153 4.4e-145 S serine-type endopeptidase activity
APMBIKAL_02155 0.0 S ATP-dependent DNA helicase activity
APMBIKAL_02159 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
APMBIKAL_02160 1e-84 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
APMBIKAL_02161 1.5e-247 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
APMBIKAL_02162 5.9e-208 yxbF K Bacterial regulatory proteins, tetR family
APMBIKAL_02163 8.2e-151 IQ Enoyl-(Acyl carrier protein) reductase
APMBIKAL_02165 0.0 htpG O Molecular chaperone. Has ATPase activity
APMBIKAL_02166 3.3e-245 csbC EGP Major facilitator Superfamily
APMBIKAL_02167 8.3e-48 yxcD S Protein of unknown function (DUF2653)
APMBIKAL_02169 8.3e-176 iolS C Aldo keto reductase
APMBIKAL_02170 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
APMBIKAL_02171 3e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
APMBIKAL_02172 1.3e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
APMBIKAL_02173 4.9e-179 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
APMBIKAL_02174 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
APMBIKAL_02175 4.7e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
APMBIKAL_02176 9.7e-215 iolF EGP Major facilitator Superfamily
APMBIKAL_02177 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
APMBIKAL_02178 8.6e-167 iolH G Xylose isomerase-like TIM barrel
APMBIKAL_02179 1.1e-147 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
APMBIKAL_02180 5.4e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
APMBIKAL_02181 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APMBIKAL_02182 7.6e-180 T PhoQ Sensor
APMBIKAL_02183 9.4e-141 yxdL V ABC transporter, ATP-binding protein
APMBIKAL_02184 0.0 yxdM V ABC transporter (permease)
APMBIKAL_02185 3.4e-58 yxeA S Protein of unknown function (DUF1093)
APMBIKAL_02186 1.1e-175 fhuD P ABC transporter
APMBIKAL_02187 8.5e-69
APMBIKAL_02188 9.6e-16 yxeD
APMBIKAL_02189 1.3e-20 yxeE
APMBIKAL_02192 3.1e-150 yidA S hydrolases of the HAD superfamily
APMBIKAL_02193 2.7e-185 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
APMBIKAL_02194 8.3e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APMBIKAL_02195 1.7e-90 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APMBIKAL_02196 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
APMBIKAL_02197 1.2e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
APMBIKAL_02198 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
APMBIKAL_02199 3.6e-213 yxeP 3.5.1.47 E hydrolase activity
APMBIKAL_02200 4.4e-247 yxeQ S MmgE/PrpD family
APMBIKAL_02201 8.3e-199 eutH E Ethanolamine utilisation protein, EutH
APMBIKAL_02202 2e-152 yxxB S Domain of Unknown Function (DUF1206)
APMBIKAL_02203 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
APMBIKAL_02204 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
APMBIKAL_02205 2.2e-205 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
APMBIKAL_02206 2.1e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
APMBIKAL_02207 3.4e-250 lysP E amino acid
APMBIKAL_02208 1.5e-180 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
APMBIKAL_02209 8.2e-235 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
APMBIKAL_02210 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
APMBIKAL_02211 1.5e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
APMBIKAL_02212 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
APMBIKAL_02213 1.3e-276 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
APMBIKAL_02214 1.1e-58 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
APMBIKAL_02216 0.0 L HKD family nuclease
APMBIKAL_02217 4.6e-21 S Domain of unknown function (DUF5082)
APMBIKAL_02218 3.1e-38 yxiC S Family of unknown function (DUF5344)
APMBIKAL_02219 7.8e-214 S nuclease activity
APMBIKAL_02220 5.5e-53
APMBIKAL_02221 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APMBIKAL_02222 4.2e-280 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
APMBIKAL_02223 5.4e-72 yxiE T Belongs to the universal stress protein A family
APMBIKAL_02224 7.1e-122 1.14.11.45 E 2OG-Fe dioxygenase
APMBIKAL_02225 1.7e-126 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APMBIKAL_02226 9.6e-164 yxxF EG EamA-like transporter family
APMBIKAL_02227 0.0 wapA M COG3209 Rhs family protein
APMBIKAL_02228 2e-54
APMBIKAL_02230 1.1e-142
APMBIKAL_02231 4.2e-75 S Protein of unknown function (DUF4240)
APMBIKAL_02232 8.4e-10 S Protein of unknown function (DUF4240)
APMBIKAL_02233 1.8e-75
APMBIKAL_02234 1.1e-66 yxiG
APMBIKAL_02235 2.6e-52 yxxG
APMBIKAL_02236 2.4e-22 S Protein of unknown function (DUF2750)
APMBIKAL_02238 1.3e-138
APMBIKAL_02239 1.3e-84 yxiI S Protein of unknown function (DUF2716)
APMBIKAL_02240 1.5e-34
APMBIKAL_02243 3.1e-44 yxiJ S YxiJ-like protein
APMBIKAL_02246 1.7e-61 S Protein of unknown function (DUF2812)
APMBIKAL_02247 1.9e-53 padR K Transcriptional regulator PadR-like family
APMBIKAL_02248 7.5e-211 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
APMBIKAL_02249 5.6e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
APMBIKAL_02250 2.3e-229 yxiO S COG2270 Permeases of the major facilitator superfamily
APMBIKAL_02251 1.1e-111
APMBIKAL_02252 4.1e-150 licT K transcriptional antiterminator
APMBIKAL_02253 1.2e-142 exoK GH16 M licheninase activity
APMBIKAL_02254 6.6e-224 citH C Citrate transporter
APMBIKAL_02255 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
APMBIKAL_02256 3e-47 yxiS
APMBIKAL_02257 4.2e-105 T Domain of unknown function (DUF4163)
APMBIKAL_02258 1.2e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
APMBIKAL_02259 5.5e-158 rlmA 2.1.1.187 Q Methyltransferase domain
APMBIKAL_02260 9.1e-251 yxjC EG COG2610 H gluconate symporter and related permeases
APMBIKAL_02261 1.8e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
APMBIKAL_02262 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
APMBIKAL_02263 2.8e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
APMBIKAL_02264 8.2e-218 yxjG 2.1.1.14 E Methionine synthase
APMBIKAL_02265 1.3e-220 yxjG 2.1.1.14 E Methionine synthase
APMBIKAL_02266 3.2e-86 yxjI S LURP-one-related
APMBIKAL_02269 8.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
APMBIKAL_02270 2.1e-109 K helix_turn_helix, Lux Regulon
APMBIKAL_02271 1.2e-190 yxjM T Signal transduction histidine kinase
APMBIKAL_02272 1e-76 S Protein of unknown function (DUF1453)
APMBIKAL_02273 2.3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
APMBIKAL_02274 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
APMBIKAL_02275 5.7e-272 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
APMBIKAL_02276 1.2e-163 lrp QT PucR C-terminal helix-turn-helix domain
APMBIKAL_02277 5.9e-205 msmK P Belongs to the ABC transporter superfamily
APMBIKAL_02278 1.8e-153 yxkH G Polysaccharide deacetylase
APMBIKAL_02280 4.7e-310 3.4.24.84 O Peptidase family M48
APMBIKAL_02281 2.1e-228 cimH C COG3493 Na citrate symporter
APMBIKAL_02282 6.9e-267 cydA 1.10.3.14 C oxidase, subunit
APMBIKAL_02283 1.2e-188 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
APMBIKAL_02284 2.4e-311 cydD V ATP-binding
APMBIKAL_02285 0.0 cydD V ATP-binding protein
APMBIKAL_02286 6.3e-159 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
APMBIKAL_02287 6.6e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
APMBIKAL_02288 1.1e-84 sigY K Belongs to the sigma-70 factor family. ECF subfamily
APMBIKAL_02289 3.9e-48 yxlC S Family of unknown function (DUF5345)
APMBIKAL_02290 1.2e-31
APMBIKAL_02291 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
APMBIKAL_02292 4.8e-165 yxlF V ABC transporter, ATP-binding protein
APMBIKAL_02293 2.6e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
APMBIKAL_02294 1.6e-211 yxlH EGP Major facilitator Superfamily
APMBIKAL_02295 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
APMBIKAL_02296 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
APMBIKAL_02297 1.1e-19 yxzF
APMBIKAL_02298 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
APMBIKAL_02299 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
APMBIKAL_02300 2.8e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APMBIKAL_02301 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
APMBIKAL_02302 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
APMBIKAL_02303 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
APMBIKAL_02304 1.2e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
APMBIKAL_02305 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
APMBIKAL_02306 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APMBIKAL_02307 1.2e-232 dltB M membrane protein involved in D-alanine export
APMBIKAL_02308 1.1e-289 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APMBIKAL_02309 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
APMBIKAL_02310 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
APMBIKAL_02311 4e-130 ynfM EGP Major facilitator Superfamily
APMBIKAL_02312 4.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
APMBIKAL_02313 1.4e-92 K Helix-turn-helix XRE-family like proteins
APMBIKAL_02314 2e-250 ywaD 3.4.11.10, 3.4.11.6 S PA domain
APMBIKAL_02315 1.9e-231 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
APMBIKAL_02316 2e-86 ywaE K Transcriptional regulator
APMBIKAL_02317 1.3e-123 ywaF S Integral membrane protein
APMBIKAL_02318 4.5e-168 gspA M General stress
APMBIKAL_02319 1.2e-152 sacY K transcriptional antiterminator
APMBIKAL_02320 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APMBIKAL_02321 4.6e-269 epr 3.4.21.62 O Belongs to the peptidase S8 family
APMBIKAL_02322 3.6e-241 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APMBIKAL_02323 9.9e-67 ywbC 4.4.1.5 E glyoxalase
APMBIKAL_02324 5.4e-220 ywbD 2.1.1.191 J Methyltransferase
APMBIKAL_02325 4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
APMBIKAL_02326 1.1e-207 ywbF EGP Major facilitator Superfamily
APMBIKAL_02327 2.3e-111 ywbG M effector of murein hydrolase
APMBIKAL_02328 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
APMBIKAL_02329 1.6e-152 ywbI K Transcriptional regulator
APMBIKAL_02330 2.4e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
APMBIKAL_02331 9.4e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
APMBIKAL_02332 3.1e-254 P COG0672 High-affinity Fe2 Pb2 permease
APMBIKAL_02333 1e-183 ycdO P periplasmic lipoprotein involved in iron transport
APMBIKAL_02334 4.9e-224 ywbN P Dyp-type peroxidase family protein
APMBIKAL_02335 6.1e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
APMBIKAL_02336 3.1e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APMBIKAL_02337 9.8e-49 ywcB S Protein of unknown function, DUF485
APMBIKAL_02339 1.1e-121 ywcC K transcriptional regulator
APMBIKAL_02340 9.5e-60 gtcA S GtrA-like protein
APMBIKAL_02341 3.4e-227 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
APMBIKAL_02342 3e-303 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
APMBIKAL_02343 1e-35 ywzA S membrane
APMBIKAL_02344 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
APMBIKAL_02345 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
APMBIKAL_02346 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
APMBIKAL_02347 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
APMBIKAL_02348 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
APMBIKAL_02349 1.4e-204 S Acetyltransferase
APMBIKAL_02350 1.1e-188 rodA D Belongs to the SEDS family
APMBIKAL_02351 2.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
APMBIKAL_02352 3.3e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APMBIKAL_02353 0.0 vpr O Belongs to the peptidase S8 family
APMBIKAL_02355 1.2e-149 sacT K transcriptional antiterminator
APMBIKAL_02356 5.7e-138 focA P Formate/nitrite transporter
APMBIKAL_02357 1.6e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APMBIKAL_02358 6.8e-278 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
APMBIKAL_02359 2e-28 ywdA
APMBIKAL_02360 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
APMBIKAL_02361 1.1e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
APMBIKAL_02362 9.5e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
APMBIKAL_02363 1.6e-260 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
APMBIKAL_02364 6.6e-48 ywdI S Family of unknown function (DUF5327)
APMBIKAL_02365 3.7e-238 ywdJ F Xanthine uracil
APMBIKAL_02366 4.3e-59 ywdK S small membrane protein
APMBIKAL_02367 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
APMBIKAL_02368 1.8e-144 spsA M Spore Coat
APMBIKAL_02369 2.3e-267 spsB M Capsule polysaccharide biosynthesis protein
APMBIKAL_02370 3e-223 spsC E Belongs to the DegT DnrJ EryC1 family
APMBIKAL_02371 1.2e-163 spsD 2.3.1.210 K Spore Coat
APMBIKAL_02372 1.6e-213 spsE 2.5.1.56 M acid synthase
APMBIKAL_02373 9.7e-132 spsF M Spore Coat
APMBIKAL_02374 2e-186 spsG M Spore Coat
APMBIKAL_02375 7.1e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
APMBIKAL_02376 1.5e-180 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
APMBIKAL_02377 4.5e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
APMBIKAL_02378 1.3e-86 spsL 5.1.3.13 M Spore Coat
APMBIKAL_02379 1.2e-77
APMBIKAL_02380 2.8e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
APMBIKAL_02381 3e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
APMBIKAL_02382 0.0 rocB E arginine degradation protein
APMBIKAL_02383 7.4e-250 lysP E amino acid
APMBIKAL_02384 1.5e-204 ywfA EGP Major facilitator Superfamily
APMBIKAL_02385 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
APMBIKAL_02386 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
APMBIKAL_02387 1.5e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APMBIKAL_02388 4.7e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
APMBIKAL_02389 1.9e-209 bacE EGP Major facilitator Superfamily
APMBIKAL_02390 2.7e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
APMBIKAL_02391 2.9e-137 IQ Enoyl-(Acyl carrier protein) reductase
APMBIKAL_02392 3.3e-146 ywfI C May function as heme-dependent peroxidase
APMBIKAL_02393 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
APMBIKAL_02394 1.1e-156 cysL K Transcriptional regulator
APMBIKAL_02395 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
APMBIKAL_02396 1.7e-157 ywfM EG EamA-like transporter family
APMBIKAL_02397 1e-110 rsfA_1
APMBIKAL_02398 3.1e-36 ywzC S Belongs to the UPF0741 family
APMBIKAL_02399 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
APMBIKAL_02400 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
APMBIKAL_02401 6.2e-79 yffB K Transcriptional regulator
APMBIKAL_02402 2e-237 mmr U Major Facilitator Superfamily
APMBIKAL_02404 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
APMBIKAL_02405 9.5e-71 ywhA K Transcriptional regulator
APMBIKAL_02406 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
APMBIKAL_02407 5.1e-119 ywhC S Peptidase family M50
APMBIKAL_02408 3.4e-94 ywhD S YwhD family
APMBIKAL_02409 4.8e-49
APMBIKAL_02410 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
APMBIKAL_02411 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
APMBIKAL_02412 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
APMBIKAL_02414 2.6e-78 S aspartate phosphatase
APMBIKAL_02415 2.4e-192 ywhK CO amine dehydrogenase activity
APMBIKAL_02416 8.6e-246 ywhL CO amine dehydrogenase activity
APMBIKAL_02418 2.9e-248 L Peptidase, M16
APMBIKAL_02419 1.4e-215 2.7.1.26, 2.7.7.2 L Peptidase, M16
APMBIKAL_02420 1.5e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
APMBIKAL_02421 3.3e-132 cbiO V ABC transporter
APMBIKAL_02423 4.9e-270 C Fe-S oxidoreductases
APMBIKAL_02424 1e-07 S Bacteriocin subtilosin A
APMBIKAL_02425 4.7e-73 ywiB S protein conserved in bacteria
APMBIKAL_02426 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
APMBIKAL_02427 2.3e-213 narK P COG2223 Nitrate nitrite transporter
APMBIKAL_02428 7.7e-129 fnr K helix_turn_helix, cAMP Regulatory protein
APMBIKAL_02429 1.7e-139 ywiC S YwiC-like protein
APMBIKAL_02430 7e-86 arfM T cyclic nucleotide binding
APMBIKAL_02431 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
APMBIKAL_02432 9.7e-296 narH 1.7.5.1 C Nitrate reductase, beta
APMBIKAL_02433 6.2e-94 narJ 1.7.5.1 C nitrate reductase
APMBIKAL_02434 1.8e-124 narI 1.7.5.1 C nitrate reductase, gamma
APMBIKAL_02435 5.5e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APMBIKAL_02436 0.0 ywjA V ABC transporter
APMBIKAL_02437 3.1e-95 ywjB H RibD C-terminal domain
APMBIKAL_02438 2.7e-42 ywjC
APMBIKAL_02439 1.5e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
APMBIKAL_02440 2.3e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
APMBIKAL_02441 0.0 fadF C COG0247 Fe-S oxidoreductase
APMBIKAL_02442 3.7e-210 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
APMBIKAL_02443 1.5e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
APMBIKAL_02444 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
APMBIKAL_02445 6e-91 ywjG S Domain of unknown function (DUF2529)
APMBIKAL_02446 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
APMBIKAL_02447 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
APMBIKAL_02448 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
APMBIKAL_02449 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
APMBIKAL_02450 9.5e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
APMBIKAL_02451 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
APMBIKAL_02452 1.1e-32 rpmE J Binds the 23S rRNA
APMBIKAL_02453 5.4e-104 tdk 2.7.1.21 F thymidine kinase
APMBIKAL_02454 0.0 sfcA 1.1.1.38 C malic enzyme
APMBIKAL_02455 8.6e-160 ywkB S Membrane transport protein
APMBIKAL_02456 6e-89 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
APMBIKAL_02457 4.5e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APMBIKAL_02458 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
APMBIKAL_02459 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
APMBIKAL_02461 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
APMBIKAL_02462 6.1e-112 spoIIR S stage II sporulation protein R
APMBIKAL_02463 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
APMBIKAL_02464 1.5e-194 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
APMBIKAL_02465 1.7e-91 mntP P Probably functions as a manganese efflux pump
APMBIKAL_02466 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
APMBIKAL_02467 8.3e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
APMBIKAL_02468 3.6e-94 ywlG S Belongs to the UPF0340 family
APMBIKAL_02469 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
APMBIKAL_02470 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
APMBIKAL_02471 2.5e-62 atpI S ATP synthase
APMBIKAL_02472 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
APMBIKAL_02473 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
APMBIKAL_02474 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
APMBIKAL_02475 1.2e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
APMBIKAL_02476 1e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
APMBIKAL_02477 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
APMBIKAL_02478 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
APMBIKAL_02479 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
APMBIKAL_02480 3.1e-86 ywmA
APMBIKAL_02481 1.3e-32 ywzB S membrane
APMBIKAL_02482 2e-132 ywmB S TATA-box binding
APMBIKAL_02483 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
APMBIKAL_02484 7.5e-178 spoIID D Stage II sporulation protein D
APMBIKAL_02485 5.1e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
APMBIKAL_02486 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
APMBIKAL_02488 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
APMBIKAL_02489 2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
APMBIKAL_02490 1.9e-102 S response regulator aspartate phosphatase
APMBIKAL_02492 3.8e-84 ywmF S Peptidase M50
APMBIKAL_02493 3.8e-11 csbD K CsbD-like
APMBIKAL_02494 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
APMBIKAL_02495 6.5e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
APMBIKAL_02496 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
APMBIKAL_02497 1.7e-64 ywnA K Transcriptional regulator
APMBIKAL_02498 1.2e-112 ywnB S NAD(P)H-binding
APMBIKAL_02499 1.7e-58 ywnC S Family of unknown function (DUF5362)
APMBIKAL_02500 1.6e-143 mta K transcriptional
APMBIKAL_02501 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APMBIKAL_02502 2.2e-70 ywnF S Family of unknown function (DUF5392)
APMBIKAL_02503 5.7e-09 ywnC S Family of unknown function (DUF5362)
APMBIKAL_02504 4.1e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
APMBIKAL_02505 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
APMBIKAL_02506 7.8e-73 ywnJ S VanZ like family
APMBIKAL_02507 5.9e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
APMBIKAL_02508 1.6e-58 nrgB K Belongs to the P(II) protein family
APMBIKAL_02509 1.3e-224 amt P Ammonium transporter
APMBIKAL_02510 1.2e-77
APMBIKAL_02511 2.6e-103 phzA Q Isochorismatase family
APMBIKAL_02512 8.3e-241 ywoD EGP Major facilitator superfamily
APMBIKAL_02513 1.2e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
APMBIKAL_02514 1.2e-231 ywoF P Right handed beta helix region
APMBIKAL_02515 2.7e-211 ywoG EGP Major facilitator Superfamily
APMBIKAL_02516 4.7e-70 ywoH K COG1846 Transcriptional regulators
APMBIKAL_02517 3e-44 spoIIID K Stage III sporulation protein D
APMBIKAL_02518 3.5e-180 mbl D Rod shape-determining protein
APMBIKAL_02519 1.7e-124 flhO N flagellar basal body
APMBIKAL_02520 2.6e-141 flhP N flagellar basal body
APMBIKAL_02521 2.2e-196 S aspartate phosphatase
APMBIKAL_02522 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
APMBIKAL_02523 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
APMBIKAL_02524 2.4e-153 ywpD T Histidine kinase
APMBIKAL_02525 4e-50 srtA 3.4.22.70 M Sortase family
APMBIKAL_02526 1.1e-66 ywpF S YwpF-like protein
APMBIKAL_02527 1.9e-65 ywpG
APMBIKAL_02528 1.4e-56 ssbB L Single-stranded DNA-binding protein
APMBIKAL_02529 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
APMBIKAL_02530 7.4e-155 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
APMBIKAL_02531 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
APMBIKAL_02532 1e-306 ywqB S SWIM zinc finger
APMBIKAL_02533 1.2e-17
APMBIKAL_02534 2e-116 ywqC M biosynthesis protein
APMBIKAL_02535 2.2e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
APMBIKAL_02536 6.7e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
APMBIKAL_02537 3.7e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
APMBIKAL_02538 8.4e-131 ywqG S Domain of unknown function (DUF1963)
APMBIKAL_02539 9.7e-23 S Domain of unknown function (DUF5082)
APMBIKAL_02540 3.9e-38 ywqI S Family of unknown function (DUF5344)
APMBIKAL_02541 1.7e-212 ywqJ S Pre-toxin TG
APMBIKAL_02542 7.9e-43
APMBIKAL_02543 5.2e-17
APMBIKAL_02544 1.3e-78 ywqJ S Pre-toxin TG
APMBIKAL_02545 1.4e-75
APMBIKAL_02546 7.4e-51
APMBIKAL_02548 3.7e-98
APMBIKAL_02549 2.6e-121 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
APMBIKAL_02550 1.9e-161 K Transcriptional regulator
APMBIKAL_02551 1.3e-99 ywqN S NAD(P)H-dependent
APMBIKAL_02553 9.3e-87 ywrA P COG2059 Chromate transport protein ChrA
APMBIKAL_02554 3.5e-103 ywrB P Chromate transporter
APMBIKAL_02555 8e-82 ywrC K Transcriptional regulator
APMBIKAL_02556 3.9e-303 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
APMBIKAL_02557 5e-54 S Domain of unknown function (DUF4181)
APMBIKAL_02558 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
APMBIKAL_02559 3.7e-12
APMBIKAL_02560 3.5e-210 cotH M Spore Coat
APMBIKAL_02561 8.2e-131 cotB
APMBIKAL_02562 3.1e-124 ywrJ
APMBIKAL_02563 3.9e-218 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
APMBIKAL_02564 1.1e-169 alsR K LysR substrate binding domain
APMBIKAL_02565 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
APMBIKAL_02566 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
APMBIKAL_02567 1.4e-95 ywrO S NADPH-quinone reductase (modulator of drug activity B)
APMBIKAL_02568 8e-48 ywsA S Protein of unknown function (DUF3892)
APMBIKAL_02569 5.2e-90 batE T Sh3 type 3 domain protein
APMBIKAL_02570 4.4e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
APMBIKAL_02571 2.1e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
APMBIKAL_02572 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
APMBIKAL_02573 2.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
APMBIKAL_02574 6.5e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APMBIKAL_02575 2.7e-177 rbsR K transcriptional
APMBIKAL_02576 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
APMBIKAL_02577 8.6e-70 pgsC S biosynthesis protein
APMBIKAL_02578 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
APMBIKAL_02579 1.4e-20 ywtC
APMBIKAL_02580 2.9e-238 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
APMBIKAL_02581 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
APMBIKAL_02582 5e-139 ywtF K Transcriptional regulator
APMBIKAL_02583 2.7e-247 ywtG EGP Major facilitator Superfamily
APMBIKAL_02584 1.3e-210 gerAC S Spore germination protein
APMBIKAL_02585 5.4e-198 gerBB E Spore germination protein
APMBIKAL_02586 3.9e-265 gerBA EG Spore germination protein
APMBIKAL_02587 4.6e-190 pmi 5.3.1.8 G mannose-6-phosphate isomerase
APMBIKAL_02588 1.6e-216 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
APMBIKAL_02589 1.1e-190 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
APMBIKAL_02590 1.2e-140 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
APMBIKAL_02591 4.9e-69 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
APMBIKAL_02592 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
APMBIKAL_02593 1.3e-282 tagF2 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
APMBIKAL_02595 5.3e-19 M transferase activity, transferring glycosyl groups
APMBIKAL_02596 4.8e-135 tagG GM Transport permease protein
APMBIKAL_02597 1.1e-159 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
APMBIKAL_02598 1e-09 L COG2963 Transposase and inactivated derivatives
APMBIKAL_02599 2.1e-160 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
APMBIKAL_02600 6.5e-207 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
APMBIKAL_02601 2.1e-36 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
APMBIKAL_02602 3.8e-08 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
APMBIKAL_02603 2.9e-11
APMBIKAL_02604 0.0 lytB 3.5.1.28 D Stage II sporulation protein
APMBIKAL_02605 2.3e-260 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
APMBIKAL_02606 4.7e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
APMBIKAL_02607 2.5e-232 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APMBIKAL_02608 4.2e-201 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
APMBIKAL_02609 8.4e-238 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
APMBIKAL_02611 1.9e-243 tuaE M Teichuronic acid biosynthesis protein
APMBIKAL_02612 3.5e-107 tuaF M protein involved in exopolysaccharide biosynthesis
APMBIKAL_02613 4.4e-135 tuaG GT2 M Glycosyltransferase like family 2
APMBIKAL_02614 3e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
APMBIKAL_02615 3.4e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
APMBIKAL_02616 1e-13
APMBIKAL_02617 6.7e-79 V ABC transporter, ATP-binding protein
APMBIKAL_02618 1e-28 S CytoplasmicMembrane, score 9.99
APMBIKAL_02620 5.9e-42 S Psort location CytoplasmicMembrane, score
APMBIKAL_02624 1.3e-113 yvhJ K Transcriptional regulator
APMBIKAL_02625 4.9e-106 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
APMBIKAL_02626 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
APMBIKAL_02627 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APMBIKAL_02628 1.4e-153 degV S protein conserved in bacteria
APMBIKAL_02629 2.4e-267 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
APMBIKAL_02630 3.7e-45 comFB S Late competence development protein ComFB
APMBIKAL_02631 6.8e-125 comFC S Phosphoribosyl transferase domain
APMBIKAL_02632 7e-74 yvyF S flagellar protein
APMBIKAL_02633 2.3e-38 flgM KNU Negative regulator of flagellin synthesis
APMBIKAL_02634 1e-76 flgN NOU FlgN protein
APMBIKAL_02635 1.2e-264 flgK N flagellar hook-associated protein
APMBIKAL_02636 7.8e-155 flgL N Belongs to the bacterial flagellin family
APMBIKAL_02637 1.3e-49 yviE
APMBIKAL_02638 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
APMBIKAL_02639 9.7e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
APMBIKAL_02640 1.5e-124 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
APMBIKAL_02641 4.4e-55 flaG N flagellar protein FlaG
APMBIKAL_02642 3.4e-256 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
APMBIKAL_02643 6.5e-69 fliS N flagellar protein FliS
APMBIKAL_02644 2.5e-08 fliT S bacterial-type flagellum organization
APMBIKAL_02645 2.8e-66
APMBIKAL_02646 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
APMBIKAL_02647 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
APMBIKAL_02648 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
APMBIKAL_02649 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
APMBIKAL_02650 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
APMBIKAL_02651 2.7e-123 ftsE D cell division ATP-binding protein FtsE
APMBIKAL_02652 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
APMBIKAL_02653 4.5e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
APMBIKAL_02654 5.3e-56 swrA S Swarming motility protein
APMBIKAL_02655 5.4e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
APMBIKAL_02656 9.6e-226 yvkA EGP Major facilitator Superfamily
APMBIKAL_02657 2.9e-99 yvkB K Transcriptional regulator
APMBIKAL_02658 0.0 yvkC 2.7.9.2 GT Phosphotransferase
APMBIKAL_02659 1.2e-30 csbA S protein conserved in bacteria
APMBIKAL_02660 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
APMBIKAL_02661 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
APMBIKAL_02662 8e-123 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
APMBIKAL_02663 5.7e-33 yvkN
APMBIKAL_02664 1.8e-48 yvlA
APMBIKAL_02665 2.4e-166 yvlB S Putative adhesin
APMBIKAL_02666 2.6e-26 pspB KT PspC domain
APMBIKAL_02667 1.2e-50 yvlD S Membrane
APMBIKAL_02668 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
APMBIKAL_02669 3.6e-134 yvoA K transcriptional
APMBIKAL_02670 7e-130 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
APMBIKAL_02671 1.7e-218 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
APMBIKAL_02672 2.9e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
APMBIKAL_02673 3.2e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
APMBIKAL_02674 5.3e-162 yvoD P COG0370 Fe2 transport system protein B
APMBIKAL_02675 3.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
APMBIKAL_02676 8.7e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
APMBIKAL_02677 5.1e-119 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
APMBIKAL_02678 3.8e-139 yvpB NU protein conserved in bacteria
APMBIKAL_02679 2.4e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
APMBIKAL_02680 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
APMBIKAL_02681 3.8e-227 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
APMBIKAL_02682 4.7e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
APMBIKAL_02683 6.2e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
APMBIKAL_02684 1.1e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
APMBIKAL_02685 1.8e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
APMBIKAL_02686 2e-112 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
APMBIKAL_02687 2.9e-51
APMBIKAL_02688 1.1e-74
APMBIKAL_02689 0.0
APMBIKAL_02691 0.0 msbA2 3.6.3.44 V ABC transporter
APMBIKAL_02692 4.5e-277 S COG0457 FOG TPR repeat
APMBIKAL_02693 1.1e-97 usp CBM50 M protein conserved in bacteria
APMBIKAL_02694 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
APMBIKAL_02695 3.9e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
APMBIKAL_02696 5.7e-166 rapZ S Displays ATPase and GTPase activities
APMBIKAL_02697 2.8e-177 ybhK S Required for morphogenesis under gluconeogenic growth conditions
APMBIKAL_02698 1.4e-170 whiA K May be required for sporulation
APMBIKAL_02699 1.6e-36 crh G Phosphocarrier protein Chr
APMBIKAL_02700 3.2e-141 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
APMBIKAL_02701 3.3e-32
APMBIKAL_02702 1.5e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APMBIKAL_02703 1.3e-196 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
APMBIKAL_02704 5.6e-141 yvcR V ABC transporter, ATP-binding protein
APMBIKAL_02705 0.0 yxdM V ABC transporter (permease)
APMBIKAL_02706 4.3e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APMBIKAL_02707 2.2e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
APMBIKAL_02708 6.2e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
APMBIKAL_02709 1.5e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
APMBIKAL_02710 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
APMBIKAL_02711 1.5e-172 yvdE K Transcriptional regulator
APMBIKAL_02712 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
APMBIKAL_02713 1.1e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
APMBIKAL_02714 2e-244 malC P COG1175 ABC-type sugar transport systems, permease components
APMBIKAL_02715 9.5e-147 malD P transport
APMBIKAL_02716 2.4e-156 malA S Protein of unknown function (DUF1189)
APMBIKAL_02717 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
APMBIKAL_02718 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
APMBIKAL_02719 2.8e-117 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
APMBIKAL_02720 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
APMBIKAL_02722 1.2e-182 S Patatin-like phospholipase
APMBIKAL_02723 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
APMBIKAL_02724 6.3e-93 yvdQ S Protein of unknown function (DUF3231)
APMBIKAL_02725 2.7e-49 sugE P Small Multidrug Resistance protein
APMBIKAL_02726 6.7e-51 ykkC P Small Multidrug Resistance protein
APMBIKAL_02727 7.4e-106 yvdT K Transcriptional regulator
APMBIKAL_02728 1.8e-295 yveA E amino acid
APMBIKAL_02729 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
APMBIKAL_02730 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
APMBIKAL_02731 7.9e-260 pbpE V Beta-lactamase
APMBIKAL_02732 2.2e-125 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
APMBIKAL_02733 2.1e-71 MA20_18690 S Protein of unknown function (DUF3237)
APMBIKAL_02734 6.6e-92 padC Q Phenolic acid decarboxylase
APMBIKAL_02736 8.5e-284 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
APMBIKAL_02737 6.3e-76 slr K transcriptional
APMBIKAL_02738 4e-122 ywqC M biosynthesis protein
APMBIKAL_02739 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
APMBIKAL_02740 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
APMBIKAL_02741 1.2e-219 epsD GT4 M Glycosyl transferase 4-like
APMBIKAL_02742 4.5e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
APMBIKAL_02743 1.3e-215 epsF GT4 M Glycosyl transferases group 1
APMBIKAL_02744 1.1e-206 epsG S EpsG family
APMBIKAL_02745 5.2e-195 epsH GT2 S Glycosyltransferase like family 2
APMBIKAL_02746 4.4e-205 epsI GM pyruvyl transferase
APMBIKAL_02747 2.2e-193 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
APMBIKAL_02748 3.5e-256 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APMBIKAL_02749 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
APMBIKAL_02750 2.1e-56 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
APMBIKAL_02751 1.6e-221 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
APMBIKAL_02752 1.4e-186 yvfF GM Exopolysaccharide biosynthesis protein
APMBIKAL_02753 1e-31 yvfG S YvfG protein
APMBIKAL_02754 2e-239 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
APMBIKAL_02755 3.7e-307 yvfH C L-lactate permease
APMBIKAL_02756 1e-112 yvfI K COG2186 Transcriptional regulators
APMBIKAL_02757 1.8e-184 lacR K Transcriptional regulator
APMBIKAL_02758 2.3e-229 cycB G COG2182 Maltose-binding periplasmic proteins domains
APMBIKAL_02759 1.1e-231 malC P COG1175 ABC-type sugar transport systems, permease components
APMBIKAL_02760 7.2e-150 ganQ P transport
APMBIKAL_02761 0.0 lacA 3.2.1.23 G beta-galactosidase
APMBIKAL_02762 1e-248 galA 3.2.1.89 G arabinogalactan
APMBIKAL_02763 7.7e-198 rsbU 3.1.3.3 T response regulator
APMBIKAL_02764 2.6e-157 rsbQ S Alpha/beta hydrolase family
APMBIKAL_02765 6.8e-159 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
APMBIKAL_02766 9.9e-132 yvfS V COG0842 ABC-type multidrug transport system, permease component
APMBIKAL_02767 1.3e-196 desK 2.7.13.3 T Histidine kinase
APMBIKAL_02768 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APMBIKAL_02769 6.5e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
APMBIKAL_02770 3.9e-273 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
APMBIKAL_02771 6.5e-128 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
APMBIKAL_02772 8.9e-179 yvbX S Glycosyl hydrolase
APMBIKAL_02773 1.1e-240 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
APMBIKAL_02774 7.2e-156 yvbV EG EamA-like transporter family
APMBIKAL_02775 5.1e-159 yvbU K Transcriptional regulator
APMBIKAL_02776 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APMBIKAL_02777 2.1e-202 araR K transcriptional
APMBIKAL_02778 6.2e-252 araE EGP Major facilitator Superfamily
APMBIKAL_02779 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
APMBIKAL_02780 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
APMBIKAL_02781 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
APMBIKAL_02782 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
APMBIKAL_02783 3.7e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
APMBIKAL_02784 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
APMBIKAL_02785 7.7e-82 yvbK 3.1.3.25 K acetyltransferase
APMBIKAL_02786 0.0 tcaA S response to antibiotic
APMBIKAL_02787 8e-123 exoY M Membrane
APMBIKAL_02788 6.2e-111 yvbH S YvbH-like oligomerisation region
APMBIKAL_02789 1.9e-102 yvbG U UPF0056 membrane protein
APMBIKAL_02790 1.4e-98 yvbF K Belongs to the GbsR family
APMBIKAL_02791 1.3e-210 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
APMBIKAL_02792 7.8e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
APMBIKAL_02793 9.4e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
APMBIKAL_02794 1.1e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
APMBIKAL_02795 7.4e-60 yvbF K Belongs to the GbsR family
APMBIKAL_02796 1.4e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
APMBIKAL_02797 5.6e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
APMBIKAL_02798 2.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
APMBIKAL_02799 5.8e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
APMBIKAL_02800 9.1e-213 NT chemotaxis protein
APMBIKAL_02801 2.2e-54 yodB K transcriptional
APMBIKAL_02802 1.2e-68 yvaO K Cro/C1-type HTH DNA-binding domain
APMBIKAL_02803 4.4e-68 K transcriptional
APMBIKAL_02804 7.5e-36 yvzC K Transcriptional
APMBIKAL_02805 3.4e-151 yvaM S Serine aminopeptidase, S33
APMBIKAL_02806 2.4e-23 secG U Preprotein translocase subunit SecG
APMBIKAL_02807 5.6e-143 est 3.1.1.1 S Carboxylesterase
APMBIKAL_02808 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
APMBIKAL_02809 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
APMBIKAL_02811 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
APMBIKAL_02812 2.7e-97 K Bacterial regulatory proteins, tetR family
APMBIKAL_02813 2.4e-54 yvaE P Small Multidrug Resistance protein
APMBIKAL_02814 5.7e-73 yvaD S Family of unknown function (DUF5360)
APMBIKAL_02815 0.0 yvaC S Fusaric acid resistance protein-like
APMBIKAL_02816 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
APMBIKAL_02817 2.8e-196 yvaA 1.1.1.371 S Oxidoreductase
APMBIKAL_02818 2.2e-48 csoR S transcriptional
APMBIKAL_02819 5.9e-29 copZ P Copper resistance protein CopZ
APMBIKAL_02820 0.0 copA 3.6.3.54 P P-type ATPase
APMBIKAL_02821 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
APMBIKAL_02822 1.6e-104 bdbD O Thioredoxin
APMBIKAL_02823 6.5e-72 bdbC O Required for disulfide bond formation in some proteins
APMBIKAL_02824 4.1e-107 yvgT S membrane
APMBIKAL_02825 0.0 helD 3.6.4.12 L DNA helicase
APMBIKAL_02826 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
APMBIKAL_02827 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
APMBIKAL_02828 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
APMBIKAL_02829 2.1e-85 yvgO
APMBIKAL_02830 1.1e-155 yvgN S reductase
APMBIKAL_02831 4e-119 modB P COG4149 ABC-type molybdate transport system, permease component
APMBIKAL_02832 6e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
APMBIKAL_02833 2.9e-168 yvgK P COG1910 Periplasmic molybdate-binding protein domain
APMBIKAL_02834 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
APMBIKAL_02835 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
APMBIKAL_02836 6.5e-16 S Small spore protein J (Spore_SspJ)
APMBIKAL_02837 4.9e-236 yvsH E Arginine ornithine antiporter
APMBIKAL_02838 2.6e-177 fhuD P ABC transporter
APMBIKAL_02839 7.9e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APMBIKAL_02840 5.5e-173 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APMBIKAL_02841 1.4e-147 fhuC 3.6.3.34 HP ABC transporter
APMBIKAL_02842 4.2e-172 M Efflux transporter rnd family, mfp subunit
APMBIKAL_02843 6e-123 macB V ABC transporter, ATP-binding protein
APMBIKAL_02844 5.3e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
APMBIKAL_02845 1.3e-64 yvrL S Regulatory protein YrvL
APMBIKAL_02846 1.1e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
APMBIKAL_02847 2.4e-19 S YvrJ protein family
APMBIKAL_02848 9.5e-98 yvrI K RNA polymerase
APMBIKAL_02849 7.2e-23
APMBIKAL_02850 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APMBIKAL_02851 0.0 T PhoQ Sensor
APMBIKAL_02852 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
APMBIKAL_02853 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
APMBIKAL_02854 8.4e-168 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
APMBIKAL_02855 1.6e-183 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APMBIKAL_02856 1.8e-240 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
APMBIKAL_02857 1.4e-101 yvqK 2.5.1.17 S Adenosyltransferase
APMBIKAL_02858 7e-226 yvqJ EGP Major facilitator Superfamily
APMBIKAL_02859 7.3e-62 liaI S membrane
APMBIKAL_02860 9.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
APMBIKAL_02861 1.1e-118 liaG S Putative adhesin
APMBIKAL_02862 1.2e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
APMBIKAL_02863 1.6e-186 vraS 2.7.13.3 T Histidine kinase
APMBIKAL_02864 3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APMBIKAL_02865 1.1e-182 gerAC S Spore germination B3/ GerAC like, C-terminal
APMBIKAL_02866 1.3e-196 gerAB E Spore germination protein
APMBIKAL_02867 3.1e-246 gerAA EG Spore germination protein
APMBIKAL_02868 2.3e-24 S Protein of unknown function (DUF3970)
APMBIKAL_02869 7.3e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
APMBIKAL_02870 1.3e-157 yuxN K Transcriptional regulator
APMBIKAL_02871 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
APMBIKAL_02872 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APMBIKAL_02873 3.1e-235 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
APMBIKAL_02874 2.7e-79 dps P Ferritin-like domain
APMBIKAL_02875 8.9e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
APMBIKAL_02876 2.5e-301 pepF2 E COG1164 Oligoendopeptidase F
APMBIKAL_02877 2.5e-66 S YusW-like protein
APMBIKAL_02878 1e-153 yusV 3.6.3.34 HP ABC transporter
APMBIKAL_02879 3.8e-47 yusU S Protein of unknown function (DUF2573)
APMBIKAL_02880 5.7e-158 yusT K LysR substrate binding domain
APMBIKAL_02881 1.3e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
APMBIKAL_02882 1.3e-63 yusQ S Tautomerase enzyme
APMBIKAL_02883 9.4e-292 yusP P Major facilitator superfamily
APMBIKAL_02884 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
APMBIKAL_02885 3.2e-53 yusN M Coat F domain
APMBIKAL_02886 5.1e-40
APMBIKAL_02887 6e-163 fadM E Proline dehydrogenase
APMBIKAL_02888 4e-08 S YuzL-like protein
APMBIKAL_02889 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
APMBIKAL_02890 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
APMBIKAL_02891 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
APMBIKAL_02892 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
APMBIKAL_02893 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
APMBIKAL_02894 1.1e-39 yusG S Protein of unknown function (DUF2553)
APMBIKAL_02895 2.1e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
APMBIKAL_02896 1.2e-54 traF CO Thioredoxin
APMBIKAL_02897 2.4e-56 yusD S SCP-2 sterol transfer family
APMBIKAL_02898 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
APMBIKAL_02899 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
APMBIKAL_02900 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
APMBIKAL_02901 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
APMBIKAL_02902 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
APMBIKAL_02903 1.4e-245 sufD O assembly protein SufD
APMBIKAL_02904 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
APMBIKAL_02905 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
APMBIKAL_02906 3.5e-271 sufB O FeS cluster assembly
APMBIKAL_02907 1.3e-63 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APMBIKAL_02908 1e-41
APMBIKAL_02910 4.9e-207 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
APMBIKAL_02911 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
APMBIKAL_02912 8.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
APMBIKAL_02913 1.2e-238 yurO G COG1653 ABC-type sugar transport system, periplasmic component
APMBIKAL_02914 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
APMBIKAL_02915 8.1e-168 yurM P COG0395 ABC-type sugar transport system, permease component
APMBIKAL_02916 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
APMBIKAL_02917 3.3e-135 yurK K UTRA
APMBIKAL_02918 6.5e-204 msmX P Belongs to the ABC transporter superfamily
APMBIKAL_02919 5.6e-158 gntR9 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
APMBIKAL_02920 4.6e-73 azlC E AzlC protein
APMBIKAL_02921 1.5e-23 S branched-chain amino acid
APMBIKAL_02922 7e-169 bsn L Ribonuclease
APMBIKAL_02923 1.7e-232 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
APMBIKAL_02924 8.7e-237 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
APMBIKAL_02925 4e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
APMBIKAL_02926 2.6e-109 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
APMBIKAL_02927 1.4e-145 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
APMBIKAL_02928 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
APMBIKAL_02929 1.8e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
APMBIKAL_02930 1.9e-56 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
APMBIKAL_02931 3.2e-278 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
APMBIKAL_02932 6.9e-221 pbuX F xanthine
APMBIKAL_02933 5.7e-234 pbuX F Permease family
APMBIKAL_02934 2.4e-300 pucR QT COG2508 Regulator of polyketide synthase expression
APMBIKAL_02935 6.6e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
APMBIKAL_02936 2.4e-59 yunG
APMBIKAL_02937 4.3e-171 yunF S Protein of unknown function DUF72
APMBIKAL_02938 2e-141 yunE S membrane transporter protein
APMBIKAL_02939 3.2e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
APMBIKAL_02940 1.1e-47 yunC S Domain of unknown function (DUF1805)
APMBIKAL_02941 1e-131 yunB S Sporulation protein YunB (Spo_YunB)
APMBIKAL_02942 4.5e-196 lytH M Peptidase, M23
APMBIKAL_02943 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
APMBIKAL_02944 2.7e-109 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
APMBIKAL_02945 9.7e-48 yutD S protein conserved in bacteria
APMBIKAL_02946 8.6e-75 yutE S Protein of unknown function DUF86
APMBIKAL_02947 4.2e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
APMBIKAL_02948 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
APMBIKAL_02949 2.9e-198 yutH S Spore coat protein
APMBIKAL_02950 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
APMBIKAL_02951 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
APMBIKAL_02952 1.9e-172 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
APMBIKAL_02953 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
APMBIKAL_02954 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
APMBIKAL_02955 8.7e-56 yuzD S protein conserved in bacteria
APMBIKAL_02956 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
APMBIKAL_02957 3.2e-39 yuzB S Belongs to the UPF0349 family
APMBIKAL_02958 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
APMBIKAL_02959 6.3e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
APMBIKAL_02960 7e-62 erpA S Belongs to the HesB IscA family
APMBIKAL_02961 1.4e-71 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APMBIKAL_02962 3.2e-115 paiB K Putative FMN-binding domain
APMBIKAL_02963 6e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
APMBIKAL_02965 1.7e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
APMBIKAL_02966 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
APMBIKAL_02967 8.4e-27 yuiB S Putative membrane protein
APMBIKAL_02968 8e-117 yuiC S protein conserved in bacteria
APMBIKAL_02969 1.2e-77 yuiD S protein conserved in bacteria
APMBIKAL_02970 8.4e-279 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
APMBIKAL_02971 3.9e-211 yuiF S antiporter
APMBIKAL_02972 4.4e-93 bioY S Biotin biosynthesis protein
APMBIKAL_02973 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
APMBIKAL_02974 1.5e-166 besA S Putative esterase
APMBIKAL_02975 3.6e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
APMBIKAL_02976 1.2e-224 entC 5.4.4.2 HQ Isochorismate synthase
APMBIKAL_02977 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
APMBIKAL_02978 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
APMBIKAL_02979 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APMBIKAL_02980 8.5e-36 mbtH S MbtH-like protein
APMBIKAL_02981 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
APMBIKAL_02982 6.1e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
APMBIKAL_02983 6.5e-229 yukF QT Transcriptional regulator
APMBIKAL_02984 2.8e-45 esxA S Belongs to the WXG100 family
APMBIKAL_02985 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
APMBIKAL_02986 6.8e-211 essB S WXG100 protein secretion system (Wss), protein YukC
APMBIKAL_02987 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
APMBIKAL_02988 0.0 esaA S type VII secretion protein EsaA
APMBIKAL_02989 3.3e-64 yueC S Family of unknown function (DUF5383)
APMBIKAL_02990 6.4e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APMBIKAL_02991 4.8e-96 yueE S phosphohydrolase
APMBIKAL_02992 2.9e-24 S Protein of unknown function (DUF2642)
APMBIKAL_02993 5.2e-71 S Protein of unknown function (DUF2283)
APMBIKAL_02994 3.2e-190 yueF S transporter activity
APMBIKAL_02995 6.6e-31 yueG S Spore germination protein gerPA/gerPF
APMBIKAL_02996 3.1e-37 yueH S YueH-like protein
APMBIKAL_02997 1.8e-66 yueI S Protein of unknown function (DUF1694)
APMBIKAL_02998 9.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
APMBIKAL_02999 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
APMBIKAL_03000 5.4e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
APMBIKAL_03001 1.1e-22 yuzC
APMBIKAL_03003 2.5e-162 comQ H Polyprenyl synthetase
APMBIKAL_03005 0.0 comP 2.7.13.3 T Histidine kinase
APMBIKAL_03006 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APMBIKAL_03007 1.8e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
APMBIKAL_03008 5.7e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
APMBIKAL_03009 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
APMBIKAL_03010 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
APMBIKAL_03011 1.1e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
APMBIKAL_03012 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
APMBIKAL_03013 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
APMBIKAL_03014 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
APMBIKAL_03015 2.1e-13
APMBIKAL_03016 1.3e-233 maeN C COG3493 Na citrate symporter
APMBIKAL_03017 1.9e-167 yufQ S Belongs to the binding-protein-dependent transport system permease family
APMBIKAL_03018 1.4e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
APMBIKAL_03019 2.7e-272 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
APMBIKAL_03020 4.2e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
APMBIKAL_03021 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
APMBIKAL_03022 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
APMBIKAL_03023 6.3e-78 yufK S Family of unknown function (DUF5366)
APMBIKAL_03024 6.3e-75 yuxK S protein conserved in bacteria
APMBIKAL_03025 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
APMBIKAL_03026 3.5e-186 yuxJ EGP Major facilitator Superfamily
APMBIKAL_03028 1.9e-115 kapD L the KinA pathway to sporulation
APMBIKAL_03029 2e-70 kapB G Kinase associated protein B
APMBIKAL_03030 1e-232 T PhoQ Sensor
APMBIKAL_03031 1.2e-227 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
APMBIKAL_03032 4.6e-39 yugE S Domain of unknown function (DUF1871)
APMBIKAL_03033 2.2e-156 yugF I Hydrolase
APMBIKAL_03034 1.6e-85 alaR K Transcriptional regulator
APMBIKAL_03035 6.2e-199 yugH 2.6.1.1 E Aminotransferase
APMBIKAL_03036 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
APMBIKAL_03037 1.1e-34 yuzA S Domain of unknown function (DUF378)
APMBIKAL_03038 2.6e-227 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
APMBIKAL_03039 2.8e-229 yugK C Dehydrogenase
APMBIKAL_03040 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
APMBIKAL_03042 1.3e-72 yugN S YugN-like family
APMBIKAL_03043 2.2e-182 yugO P COG1226 Kef-type K transport systems
APMBIKAL_03044 1.1e-53 mstX S Membrane-integrating protein Mistic
APMBIKAL_03045 4.6e-39
APMBIKAL_03046 1.4e-116 yugP S Zn-dependent protease
APMBIKAL_03047 8.4e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
APMBIKAL_03048 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
APMBIKAL_03049 2.1e-72 yugU S Uncharacterised protein family UPF0047
APMBIKAL_03050 6.7e-35
APMBIKAL_03051 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
APMBIKAL_03052 3.2e-225 mcpA NT chemotaxis protein
APMBIKAL_03053 1.1e-217 mcpA NT chemotaxis protein
APMBIKAL_03054 8.5e-295 mcpA NT chemotaxis protein
APMBIKAL_03055 2.1e-237 mcpA NT chemotaxis protein
APMBIKAL_03057 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
APMBIKAL_03058 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
APMBIKAL_03059 1.5e-272 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
APMBIKAL_03060 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
APMBIKAL_03061 1.3e-251 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
APMBIKAL_03062 1.7e-182 ygjR S Oxidoreductase
APMBIKAL_03063 9.1e-196 yubA S transporter activity
APMBIKAL_03064 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
APMBIKAL_03066 1.3e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
APMBIKAL_03067 3.7e-274 yubD P Major Facilitator Superfamily
APMBIKAL_03068 3.2e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
APMBIKAL_03069 1e-38 yiaA S yiaA/B two helix domain
APMBIKAL_03070 2.7e-236 ktrB P Potassium
APMBIKAL_03071 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
APMBIKAL_03072 2.2e-91 yuaB
APMBIKAL_03073 6.7e-93 yuaC K Belongs to the GbsR family
APMBIKAL_03074 1e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
APMBIKAL_03075 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
APMBIKAL_03076 2.1e-105 yuaD
APMBIKAL_03077 3.9e-84 yuaE S DinB superfamily
APMBIKAL_03078 4.2e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
APMBIKAL_03079 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
APMBIKAL_03080 3.4e-94 M1-753 M FR47-like protein
APMBIKAL_03081 3.7e-89 thiT S Thiamine transporter protein (Thia_YuaJ)
APMBIKAL_03082 1.3e-137 2.7.1.50, 3.5.2.6 GH19 M Lysin motif
APMBIKAL_03083 3.9e-57
APMBIKAL_03084 1.1e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
APMBIKAL_03085 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
APMBIKAL_03087 1e-167 S Alpha/beta hydrolase family
APMBIKAL_03088 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
APMBIKAL_03089 2.7e-85 ybfM S SNARE associated Golgi protein
APMBIKAL_03090 4.8e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
APMBIKAL_03091 3e-44 ybfN
APMBIKAL_03092 1.2e-252 S Erythromycin esterase
APMBIKAL_03093 1.1e-166 ybfP K Transcriptional regulator
APMBIKAL_03094 1.5e-191 yceA S Belongs to the UPF0176 family
APMBIKAL_03095 2.4e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
APMBIKAL_03096 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APMBIKAL_03097 1.5e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
APMBIKAL_03098 4.9e-128 K UTRA
APMBIKAL_03100 6.1e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
APMBIKAL_03101 5.7e-261 mmuP E amino acid
APMBIKAL_03102 3.5e-182 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
APMBIKAL_03103 5.6e-256 agcS E Sodium alanine symporter
APMBIKAL_03104 2.5e-186 glsA 3.5.1.2 E Belongs to the glutaminase family
APMBIKAL_03105 4.2e-229 phoQ 2.7.13.3 T Histidine kinase
APMBIKAL_03106 1.2e-169 glnL T Regulator
APMBIKAL_03107 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
APMBIKAL_03108 2e-272 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
APMBIKAL_03109 5.9e-255 gudP G COG0477 Permeases of the major facilitator superfamily
APMBIKAL_03110 1.5e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
APMBIKAL_03111 1.5e-124 ycbG K FCD
APMBIKAL_03112 3.1e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
APMBIKAL_03113 2.2e-173 ycbJ S Macrolide 2'-phosphotransferase
APMBIKAL_03114 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
APMBIKAL_03115 1.9e-167 eamA1 EG spore germination
APMBIKAL_03116 1.9e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APMBIKAL_03117 1.7e-168 T PhoQ Sensor
APMBIKAL_03118 2e-166 ycbN V ABC transporter, ATP-binding protein
APMBIKAL_03119 1.5e-113 S ABC-2 family transporter protein
APMBIKAL_03120 8.2e-53 ycbP S Protein of unknown function (DUF2512)
APMBIKAL_03121 2.2e-78 sleB 3.5.1.28 M Cell wall
APMBIKAL_03122 2.5e-135 ycbR T vWA found in TerF C terminus
APMBIKAL_03123 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
APMBIKAL_03124 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
APMBIKAL_03125 6.4e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
APMBIKAL_03126 1.2e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
APMBIKAL_03127 1.1e-206 ycbU E Selenocysteine lyase
APMBIKAL_03128 5.8e-229 lmrB EGP the major facilitator superfamily
APMBIKAL_03129 1.6e-100 yxaF K Transcriptional regulator
APMBIKAL_03130 2e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
APMBIKAL_03131 6.2e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
APMBIKAL_03132 3.4e-59 S RDD family
APMBIKAL_03133 2.1e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
APMBIKAL_03134 5.6e-159 2.7.13.3 T GHKL domain
APMBIKAL_03135 1.2e-126 lytR_2 T LytTr DNA-binding domain
APMBIKAL_03136 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
APMBIKAL_03137 9.3e-201 natB CP ABC-2 family transporter protein
APMBIKAL_03138 3.5e-174 yccK C Aldo keto reductase
APMBIKAL_03139 2.5e-176 ycdA S Domain of unknown function (DUF5105)
APMBIKAL_03140 1.4e-278 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
APMBIKAL_03141 2.5e-267 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
APMBIKAL_03142 1.1e-94 cwlK M D-alanyl-D-alanine carboxypeptidase
APMBIKAL_03143 1.2e-173 S response regulator aspartate phosphatase
APMBIKAL_03144 2.3e-139 IQ Enoyl-(Acyl carrier protein) reductase
APMBIKAL_03145 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
APMBIKAL_03146 1.2e-166 adcA P Belongs to the bacterial solute-binding protein 9 family
APMBIKAL_03147 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
APMBIKAL_03148 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
APMBIKAL_03149 4.2e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APMBIKAL_03150 2.5e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
APMBIKAL_03151 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
APMBIKAL_03152 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
APMBIKAL_03153 6.3e-137 terC P Protein of unknown function (DUF475)
APMBIKAL_03154 0.0 yceG S Putative component of 'biosynthetic module'
APMBIKAL_03155 2.6e-192 yceH P Belongs to the TelA family
APMBIKAL_03156 1.5e-217 naiP P Uncharacterised MFS-type transporter YbfB
APMBIKAL_03157 1.4e-207 yceJ EGP Uncharacterised MFS-type transporter YbfB
APMBIKAL_03158 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
APMBIKAL_03159 1.9e-228 proV 3.6.3.32 E glycine betaine
APMBIKAL_03160 1.3e-127 opuAB P glycine betaine
APMBIKAL_03161 5.3e-164 opuAC E glycine betaine
APMBIKAL_03162 3.7e-218 amhX S amidohydrolase
APMBIKAL_03163 5.6e-256 ycgA S Membrane
APMBIKAL_03164 4.1e-81 ycgB
APMBIKAL_03165 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
APMBIKAL_03166 4.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
APMBIKAL_03167 5.7e-289 lctP C L-lactate permease
APMBIKAL_03168 6.2e-269 mdr EGP Major facilitator Superfamily
APMBIKAL_03169 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
APMBIKAL_03170 6.8e-113 ycgF E Lysine exporter protein LysE YggA
APMBIKAL_03171 1.2e-151 yqcI S YqcI/YcgG family
APMBIKAL_03172 1.6e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
APMBIKAL_03173 2.4e-112 ycgI S Domain of unknown function (DUF1989)
APMBIKAL_03174 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
APMBIKAL_03175 7.3e-109 tmrB S AAA domain
APMBIKAL_03177 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
APMBIKAL_03178 9e-144 yafE Q ubiE/COQ5 methyltransferase family
APMBIKAL_03179 3.3e-175 oxyR3 K LysR substrate binding domain
APMBIKAL_03180 2.7e-182 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
APMBIKAL_03181 2.9e-145 ycgL S Predicted nucleotidyltransferase
APMBIKAL_03182 5.1e-170 ycgM E Proline dehydrogenase
APMBIKAL_03183 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
APMBIKAL_03184 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APMBIKAL_03185 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
APMBIKAL_03186 2.6e-147 ycgQ S membrane
APMBIKAL_03187 1.2e-139 ycgR S permeases
APMBIKAL_03188 2.8e-162 I alpha/beta hydrolase fold
APMBIKAL_03189 1.3e-193 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
APMBIKAL_03190 9.3e-283 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
APMBIKAL_03191 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
APMBIKAL_03192 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
APMBIKAL_03193 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
APMBIKAL_03194 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
APMBIKAL_03195 1.3e-221 nasA P COG2223 Nitrate nitrite transporter
APMBIKAL_03196 1.9e-169 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
APMBIKAL_03197 3.4e-106 yciB M ErfK YbiS YcfS YnhG
APMBIKAL_03198 1.6e-227 yciC S GTPases (G3E family)
APMBIKAL_03199 3.5e-115 yecS P COG0765 ABC-type amino acid transport system, permease component
APMBIKAL_03200 1.7e-130 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
APMBIKAL_03201 4e-75 yckC S membrane
APMBIKAL_03202 7.8e-52 yckD S Protein of unknown function (DUF2680)
APMBIKAL_03203 5.7e-39 K MarR family
APMBIKAL_03204 9.3e-24
APMBIKAL_03205 1.3e-120 S AAA domain
APMBIKAL_03206 7.2e-296 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
APMBIKAL_03207 8.5e-69 nin S Competence protein J (ComJ)
APMBIKAL_03208 7.8e-71 nucA M Deoxyribonuclease NucA/NucB
APMBIKAL_03209 9.6e-186 tlpC 2.7.13.3 NT chemotaxis protein
APMBIKAL_03210 4.6e-97 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
APMBIKAL_03211 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
APMBIKAL_03212 1.3e-63 hxlR K transcriptional
APMBIKAL_03213 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APMBIKAL_03214 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APMBIKAL_03215 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
APMBIKAL_03216 1.7e-139 srfAD Q thioesterase
APMBIKAL_03217 4.4e-225 EGP Major Facilitator Superfamily
APMBIKAL_03218 1.2e-84 S YcxB-like protein
APMBIKAL_03219 2.2e-160 ycxC EG EamA-like transporter family
APMBIKAL_03220 1.2e-247 ycxD K GntR family transcriptional regulator
APMBIKAL_03221 3.3e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
APMBIKAL_03222 9.7e-115 yczE S membrane
APMBIKAL_03223 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
APMBIKAL_03224 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
APMBIKAL_03225 1.2e-138 tcyA ET Belongs to the bacterial solute-binding protein 3 family
APMBIKAL_03226 1.2e-160 bsdA K LysR substrate binding domain
APMBIKAL_03227 7.6e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
APMBIKAL_03228 4.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
APMBIKAL_03229 4e-39 bsdD 4.1.1.61 S response to toxic substance
APMBIKAL_03230 5.9e-82 yclD
APMBIKAL_03231 1.4e-158 yclE 3.4.11.5 S Alpha beta hydrolase
APMBIKAL_03232 2.1e-266 dtpT E amino acid peptide transporter
APMBIKAL_03233 5e-307 yclG M Pectate lyase superfamily protein
APMBIKAL_03235 7.5e-281 gerKA EG Spore germination protein
APMBIKAL_03236 5.2e-226 gerKC S spore germination
APMBIKAL_03237 5.6e-195 gerKB F Spore germination protein
APMBIKAL_03238 5.6e-121 yclH P ABC transporter
APMBIKAL_03239 2.8e-202 yclI V ABC transporter (permease) YclI
APMBIKAL_03240 2.3e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APMBIKAL_03241 8.3e-260 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
APMBIKAL_03242 5.2e-71 S aspartate phosphatase
APMBIKAL_03245 1.7e-241 lysC 2.7.2.4 E Belongs to the aspartokinase family
APMBIKAL_03246 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APMBIKAL_03247 1.4e-162 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APMBIKAL_03248 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
APMBIKAL_03249 9.4e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
APMBIKAL_03250 4.1e-251 ycnB EGP Major facilitator Superfamily
APMBIKAL_03251 5.5e-153 ycnC K Transcriptional regulator
APMBIKAL_03252 2.2e-134 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
APMBIKAL_03253 1.6e-45 ycnE S Monooxygenase
APMBIKAL_03254 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
APMBIKAL_03255 4.4e-269 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
APMBIKAL_03256 1.5e-244 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
APMBIKAL_03257 3.8e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
APMBIKAL_03258 6.1e-149 glcU U Glucose uptake
APMBIKAL_03259 4.9e-145 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APMBIKAL_03260 5.4e-99 ycnI S protein conserved in bacteria
APMBIKAL_03261 2.1e-307 ycnJ P protein, homolog of Cu resistance protein CopC
APMBIKAL_03262 2.8e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
APMBIKAL_03263 7.3e-56
APMBIKAL_03264 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
APMBIKAL_03265 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
APMBIKAL_03266 2.4e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
APMBIKAL_03267 6.5e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
APMBIKAL_03268 2.1e-97 sipT 3.4.21.89 U Belongs to the peptidase S26 family
APMBIKAL_03269 7e-107 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
APMBIKAL_03270 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
APMBIKAL_03272 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
APMBIKAL_03273 4.7e-140 ycsF S Belongs to the UPF0271 (lamB) family
APMBIKAL_03274 1.6e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
APMBIKAL_03275 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
APMBIKAL_03276 1.8e-133 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
APMBIKAL_03277 5.6e-186 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
APMBIKAL_03278 2.1e-132 kipR K Transcriptional regulator
APMBIKAL_03279 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
APMBIKAL_03281 1.4e-49 yczJ S biosynthesis
APMBIKAL_03282 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
APMBIKAL_03283 8.3e-173 ydhF S Oxidoreductase
APMBIKAL_03284 0.0 mtlR K transcriptional regulator, MtlR
APMBIKAL_03285 1.6e-293 ydaB IQ acyl-CoA ligase
APMBIKAL_03286 3.8e-97 ydaC Q Methyltransferase domain
APMBIKAL_03287 4.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APMBIKAL_03288 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
APMBIKAL_03289 8.3e-99 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
APMBIKAL_03290 2e-76 ydaG 1.4.3.5 S general stress protein
APMBIKAL_03291 7.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
APMBIKAL_03292 2.1e-45 ydzA EGP Major facilitator Superfamily
APMBIKAL_03293 2.5e-74 lrpC K Transcriptional regulator
APMBIKAL_03294 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
APMBIKAL_03295 5.3e-206 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
APMBIKAL_03296 1.3e-151 ydaK T Diguanylate cyclase, GGDEF domain
APMBIKAL_03297 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
APMBIKAL_03298 4.5e-233 ydaM M Glycosyl transferase family group 2
APMBIKAL_03299 0.0 ydaN S Bacterial cellulose synthase subunit
APMBIKAL_03300 0.0 ydaO E amino acid
APMBIKAL_03301 1.1e-77 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
APMBIKAL_03302 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
APMBIKAL_03303 9.4e-40
APMBIKAL_03304 5e-224 mntH P H( )-stimulated, divalent metal cation uptake system
APMBIKAL_03306 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
APMBIKAL_03307 8.4e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
APMBIKAL_03309 8.9e-59 ydbB G Cupin domain
APMBIKAL_03310 1.2e-61 ydbC S Domain of unknown function (DUF4937
APMBIKAL_03311 2.3e-153 ydbD P Catalase
APMBIKAL_03312 5.7e-197 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
APMBIKAL_03313 2.8e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
APMBIKAL_03314 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
APMBIKAL_03315 1.8e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
APMBIKAL_03316 9.7e-181 ydbI S AI-2E family transporter
APMBIKAL_03317 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
APMBIKAL_03318 3.6e-124 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
APMBIKAL_03319 2.7e-52 ydbL
APMBIKAL_03320 5.7e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
APMBIKAL_03321 1.1e-18 S Fur-regulated basic protein B
APMBIKAL_03322 2.2e-07 S Fur-regulated basic protein A
APMBIKAL_03323 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
APMBIKAL_03324 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
APMBIKAL_03325 1.1e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
APMBIKAL_03326 2.8e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
APMBIKAL_03327 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
APMBIKAL_03328 2.1e-82 ydbS S Bacterial PH domain
APMBIKAL_03329 2.1e-258 ydbT S Membrane
APMBIKAL_03330 4.5e-106 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
APMBIKAL_03331 8e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
APMBIKAL_03332 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
APMBIKAL_03333 5.6e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
APMBIKAL_03334 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
APMBIKAL_03335 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
APMBIKAL_03336 4.8e-143 rsbR T Positive regulator of sigma-B
APMBIKAL_03337 5.2e-57 rsbS T antagonist
APMBIKAL_03338 2.9e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
APMBIKAL_03339 7.1e-189 rsbU 3.1.3.3 KT phosphatase
APMBIKAL_03340 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
APMBIKAL_03341 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
APMBIKAL_03342 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APMBIKAL_03343 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
APMBIKAL_03344 0.0 yhgF K COG2183 Transcriptional accessory protein
APMBIKAL_03345 8.9e-83 ydcK S Belongs to the SprT family
APMBIKAL_03353 3.2e-114 yecA E amino acid
APMBIKAL_03354 4.6e-107 K Transcriptional regulator
APMBIKAL_03355 2.5e-74 rimJ2 J Acetyltransferase (GNAT) domain
APMBIKAL_03356 1.2e-43
APMBIKAL_03357 5e-142 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
APMBIKAL_03358 5.6e-34 K Helix-turn-helix XRE-family like proteins
APMBIKAL_03359 1.9e-40
APMBIKAL_03360 1.3e-190 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
APMBIKAL_03361 8.7e-30 cspL K Cold shock
APMBIKAL_03362 6.1e-79 carD K Transcription factor
APMBIKAL_03363 4.8e-141 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
APMBIKAL_03364 1.4e-164 rhaS5 K AraC-like ligand binding domain
APMBIKAL_03365 1.3e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
APMBIKAL_03366 8.9e-164 ydeE K AraC family transcriptional regulator
APMBIKAL_03367 2.1e-260 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
APMBIKAL_03368 6.7e-216 ydeG EGP Major facilitator superfamily
APMBIKAL_03369 1.4e-44 ydeH
APMBIKAL_03370 2.1e-103 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
APMBIKAL_03371 4.5e-99
APMBIKAL_03372 1.1e-31 S SNARE associated Golgi protein
APMBIKAL_03373 4.9e-15 ptsH G PTS HPr component phosphorylation site
APMBIKAL_03374 8.8e-85 K Transcriptional regulator C-terminal region
APMBIKAL_03376 4.5e-152 ydeK EG -transporter
APMBIKAL_03377 2.3e-270 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
APMBIKAL_03378 4.6e-73 maoC I N-terminal half of MaoC dehydratase
APMBIKAL_03379 1.1e-104 ydeN S Serine hydrolase
APMBIKAL_03380 8.9e-56 K HxlR-like helix-turn-helix
APMBIKAL_03381 1.2e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
APMBIKAL_03382 4.8e-69 ydeP K Transcriptional regulator
APMBIKAL_03383 3.6e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
APMBIKAL_03384 3.6e-192 ydeR EGP Major facilitator Superfamily
APMBIKAL_03385 2.1e-103 ydeS K Transcriptional regulator
APMBIKAL_03386 2.8e-57 arsR K transcriptional
APMBIKAL_03387 1.7e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
APMBIKAL_03388 3.7e-145 ydfB J GNAT acetyltransferase
APMBIKAL_03389 2.8e-149 lytR K Transcriptional regulator
APMBIKAL_03390 1e-92 nodB1 G deacetylase
APMBIKAL_03391 4e-156
APMBIKAL_03392 4.5e-213 T GHKL domain
APMBIKAL_03393 2.6e-122 T Transcriptional regulatory protein, C terminal
APMBIKAL_03394 9.9e-142 ydfC EG EamA-like transporter family
APMBIKAL_03395 4.6e-274 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
APMBIKAL_03396 5e-116 ydfE S Flavin reductase like domain
APMBIKAL_03397 8.6e-122 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
APMBIKAL_03398 3.8e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
APMBIKAL_03400 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
APMBIKAL_03401 9.3e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APMBIKAL_03402 0.0 ydfJ S drug exporters of the RND superfamily
APMBIKAL_03403 1e-170 S Alpha/beta hydrolase family
APMBIKAL_03404 8.5e-117 S Protein of unknown function (DUF554)
APMBIKAL_03405 9.2e-147 K Bacterial transcription activator, effector binding domain
APMBIKAL_03406 5.9e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
APMBIKAL_03407 3.1e-110 ydfN C nitroreductase
APMBIKAL_03408 4e-186 ydfO E COG0346 Lactoylglutathione lyase and related lyases
APMBIKAL_03409 1.2e-62 mhqP S DoxX
APMBIKAL_03410 2e-55 traF CO Thioredoxin
APMBIKAL_03411 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
APMBIKAL_03412 6.3e-29
APMBIKAL_03414 4.4e-118 ydfR S Protein of unknown function (DUF421)
APMBIKAL_03415 4.7e-20 ydfS S Protein of unknown function (DUF421)
APMBIKAL_03416 1.5e-89 ydfS S Protein of unknown function (DUF421)
APMBIKAL_03417 2.2e-75 cotP O Belongs to the small heat shock protein (HSP20) family
APMBIKAL_03418 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
APMBIKAL_03419 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
APMBIKAL_03420 1.9e-93 K Bacterial regulatory proteins, tetR family
APMBIKAL_03421 1.8e-51 S DoxX-like family
APMBIKAL_03422 1.3e-84 yycN 2.3.1.128 K Acetyltransferase
APMBIKAL_03423 3.9e-134 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
APMBIKAL_03424 2e-119 purR K helix_turn _helix lactose operon repressor
APMBIKAL_03425 7.7e-191 csbC EGP Major facilitator Superfamily
APMBIKAL_03426 4.4e-104 G Xylose isomerase-like TIM barrel
APMBIKAL_03427 6.1e-299 expZ S ABC transporter
APMBIKAL_03428 2.9e-249 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
APMBIKAL_03429 2.5e-89 dinB S DinB family
APMBIKAL_03430 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
APMBIKAL_03431 0.0 ydgH S drug exporters of the RND superfamily
APMBIKAL_03432 3e-113 drgA C nitroreductase
APMBIKAL_03433 7.1e-69 ydgJ K Winged helix DNA-binding domain
APMBIKAL_03434 1.6e-208 tcaB EGP Major facilitator Superfamily
APMBIKAL_03435 3.5e-121 ydhB S membrane transporter protein
APMBIKAL_03436 6.5e-122 ydhC K FCD
APMBIKAL_03437 1.6e-243 ydhD M Glycosyl hydrolase
APMBIKAL_03438 2.7e-227 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
APMBIKAL_03439 7.4e-124
APMBIKAL_03440 1.5e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
APMBIKAL_03441 4.3e-67 frataxin S Domain of unknown function (DU1801)
APMBIKAL_03443 8.6e-84 K Acetyltransferase (GNAT) domain
APMBIKAL_03444 7.6e-180 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
APMBIKAL_03445 8.5e-99 ydhK M Protein of unknown function (DUF1541)
APMBIKAL_03446 4.6e-200 pbuE EGP Major facilitator Superfamily
APMBIKAL_03447 1.9e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
APMBIKAL_03448 5.1e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
APMBIKAL_03449 2.6e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APMBIKAL_03450 2.8e-284 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
APMBIKAL_03451 1.1e-132 ydhQ K UTRA
APMBIKAL_03452 2.5e-169 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
APMBIKAL_03453 6.2e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
APMBIKAL_03454 2.9e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
APMBIKAL_03455 2.3e-156 ydhU P Catalase
APMBIKAL_03458 6.7e-167 ygxA S Nucleotidyltransferase-like
APMBIKAL_03459 2.1e-55 ygzB S UPF0295 protein
APMBIKAL_03460 4e-80 perR P Belongs to the Fur family
APMBIKAL_03461 8.2e-87 bcp 1.11.1.15 O Peroxiredoxin
APMBIKAL_03462 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
APMBIKAL_03463 8.7e-180 ygaE S Membrane
APMBIKAL_03464 5.3e-301 ygaD V ABC transporter
APMBIKAL_03465 1.3e-104 ygaC J Belongs to the UPF0374 family
APMBIKAL_03466 1.5e-37 ygaB S YgaB-like protein
APMBIKAL_03467 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
APMBIKAL_03468 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APMBIKAL_03469 6.9e-36 yfhS
APMBIKAL_03470 1.1e-210 mutY L A G-specific
APMBIKAL_03471 1.2e-185 yfhP S membrane-bound metal-dependent
APMBIKAL_03472 0.0 yfhO S Bacterial membrane protein YfhO
APMBIKAL_03473 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
APMBIKAL_03474 1.1e-169 yfhM S Alpha beta hydrolase
APMBIKAL_03475 3.5e-51 yfhL S SdpI/YhfL protein family
APMBIKAL_03476 2.4e-87 batE T Bacterial SH3 domain homologues
APMBIKAL_03477 2.9e-44 yfhJ S WVELL protein
APMBIKAL_03478 6.2e-20 sspK S reproduction
APMBIKAL_03479 2.8e-208 yfhI EGP Major facilitator Superfamily
APMBIKAL_03480 3.2e-50 yfhH S Protein of unknown function (DUF1811)
APMBIKAL_03481 5.7e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
APMBIKAL_03482 1.6e-171 yfhF S nucleoside-diphosphate sugar epimerase
APMBIKAL_03484 2.1e-25 yfhD S YfhD-like protein
APMBIKAL_03485 4.4e-106 yfhC C nitroreductase
APMBIKAL_03486 2.1e-165 yfhB 5.3.3.17 S PhzF family
APMBIKAL_03487 1.5e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APMBIKAL_03488 4.9e-174 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APMBIKAL_03489 8.2e-174 yfiY P ABC transporter substrate-binding protein
APMBIKAL_03490 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
APMBIKAL_03491 4.9e-79 yfiV K transcriptional
APMBIKAL_03492 1e-282 yfiU EGP Major facilitator Superfamily
APMBIKAL_03493 2.1e-99 yfiT S Belongs to the metal hydrolase YfiT family
APMBIKAL_03494 5.3e-218 yfiS EGP Major facilitator Superfamily
APMBIKAL_03495 3.4e-109 yfiR K Transcriptional regulator
APMBIKAL_03496 4.2e-187 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
APMBIKAL_03497 3.6e-74 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
APMBIKAL_03498 1.8e-93 padR K transcriptional
APMBIKAL_03499 6.9e-204 V COG0842 ABC-type multidrug transport system, permease component
APMBIKAL_03500 1.5e-209 V ABC-2 family transporter protein
APMBIKAL_03501 1.9e-167 V ABC transporter, ATP-binding protein
APMBIKAL_03502 5.4e-113 KT LuxR family transcriptional regulator
APMBIKAL_03503 3.6e-213 yxjM T Histidine kinase
APMBIKAL_03505 1.1e-233 S Oxidoreductase
APMBIKAL_03506 8.4e-184 G Xylose isomerase
APMBIKAL_03507 1.8e-262 iolT EGP Major facilitator Superfamily
APMBIKAL_03508 1.1e-167 K AraC-like ligand binding domain
APMBIKAL_03509 9.7e-163 yfiE 1.13.11.2 S glyoxalase
APMBIKAL_03510 6.4e-64 mhqP S DoxX
APMBIKAL_03511 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
APMBIKAL_03512 1.4e-306 yfiB3 V ABC transporter
APMBIKAL_03513 0.0 yobO M COG5434 Endopolygalacturonase
APMBIKAL_03514 3e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APMBIKAL_03515 4.6e-140 glvR K Helix-turn-helix domain, rpiR family
APMBIKAL_03516 1.1e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
APMBIKAL_03517 1.9e-14 S Domain of unknown function (DUF5082)
APMBIKAL_03518 1.7e-12 yxiC S Family of unknown function (DUF5344)
APMBIKAL_03519 1.8e-74 S LXG domain of WXG superfamily
APMBIKAL_03521 1.3e-17 S Protein conserved in bacteria
APMBIKAL_03524 2.6e-44 yfjA S Belongs to the WXG100 family
APMBIKAL_03525 2.7e-190 yfjB
APMBIKAL_03526 4.1e-144 yfjC
APMBIKAL_03527 1.8e-101 yfjD S Family of unknown function (DUF5381)
APMBIKAL_03528 6.1e-78 S Family of unknown function (DUF5381)
APMBIKAL_03529 4e-56 yfjF S UPF0060 membrane protein
APMBIKAL_03530 9.8e-25 sspH S Belongs to the SspH family
APMBIKAL_03531 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
APMBIKAL_03532 8.6e-254 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
APMBIKAL_03533 7.9e-195 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
APMBIKAL_03534 2.1e-188 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
APMBIKAL_03535 4.4e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
APMBIKAL_03536 1.7e-29 yfjL
APMBIKAL_03537 9.6e-85 yfjM S Psort location Cytoplasmic, score
APMBIKAL_03538 1.5e-188 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
APMBIKAL_03539 3.3e-43 S YfzA-like protein
APMBIKAL_03540 4e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
APMBIKAL_03541 7.2e-166 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
APMBIKAL_03542 1.7e-184 corA P Mediates influx of magnesium ions
APMBIKAL_03543 9.5e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
APMBIKAL_03544 2.6e-154 pdaA G deacetylase
APMBIKAL_03545 1.1e-26 yfjT
APMBIKAL_03546 5.4e-222 yfkA S YfkB-like domain
APMBIKAL_03547 6e-149 yfkC M Mechanosensitive ion channel
APMBIKAL_03548 1.2e-146 yfkD S YfkD-like protein
APMBIKAL_03549 6.1e-183 cax P COG0387 Ca2 H antiporter
APMBIKAL_03550 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
APMBIKAL_03551 5e-08
APMBIKAL_03552 1.3e-143 yihY S Belongs to the UPF0761 family
APMBIKAL_03553 2.4e-50 yfkI S gas vesicle protein
APMBIKAL_03554 1.2e-82 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
APMBIKAL_03555 1.3e-28 yfkK S Belongs to the UPF0435 family
APMBIKAL_03556 5.8e-206 ydiM EGP Major facilitator Superfamily
APMBIKAL_03557 1.2e-88 yfkM 1.11.1.6, 3.5.1.124 S protease
APMBIKAL_03558 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
APMBIKAL_03559 1.6e-125 yfkO C nitroreductase
APMBIKAL_03560 1.8e-133 treR K transcriptional
APMBIKAL_03561 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
APMBIKAL_03562 1.5e-253 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APMBIKAL_03563 3.2e-281 yfkQ EG Spore germination protein
APMBIKAL_03564 5.1e-207 yfkR S spore germination
APMBIKAL_03566 1.3e-193 E Spore germination protein
APMBIKAL_03567 6.3e-252 agcS_1 E Sodium alanine symporter
APMBIKAL_03568 6e-67 yhdN S Domain of unknown function (DUF1992)
APMBIKAL_03569 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
APMBIKAL_03570 2e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
APMBIKAL_03571 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
APMBIKAL_03572 9.1e-50 yflH S Protein of unknown function (DUF3243)
APMBIKAL_03573 4.1e-19 yflI
APMBIKAL_03574 4e-18 yflJ S Protein of unknown function (DUF2639)
APMBIKAL_03575 9.9e-123 yflK S protein conserved in bacteria
APMBIKAL_03576 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
APMBIKAL_03577 2.8e-215 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
APMBIKAL_03578 3.5e-151 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
APMBIKAL_03579 8.5e-227 citM C Citrate transporter
APMBIKAL_03580 2.8e-179 yflP S Tripartite tricarboxylate transporter family receptor
APMBIKAL_03581 2.2e-117 citT T response regulator
APMBIKAL_03582 4.4e-289 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
APMBIKAL_03583 5.5e-235 yflS P Sodium:sulfate symporter transmembrane region
APMBIKAL_03584 2.5e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
APMBIKAL_03585 7.6e-58 yflT S Heat induced stress protein YflT
APMBIKAL_03586 2.6e-24 S Protein of unknown function (DUF3212)
APMBIKAL_03587 1.2e-166 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
APMBIKAL_03588 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APMBIKAL_03589 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APMBIKAL_03590 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
APMBIKAL_03591 3e-187 yfmJ S N-terminal domain of oxidoreductase
APMBIKAL_03592 8.5e-78 yfmK 2.3.1.128 K acetyltransferase
APMBIKAL_03593 5e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
APMBIKAL_03594 3.5e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
APMBIKAL_03597 1.5e-209 yfmO EGP Major facilitator Superfamily
APMBIKAL_03598 1.4e-69 yfmP K transcriptional
APMBIKAL_03599 1.1e-72 yfmQ S Uncharacterised protein from bacillus cereus group
APMBIKAL_03600 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
APMBIKAL_03601 1.1e-113 yfmS NT chemotaxis protein
APMBIKAL_03602 3.7e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
APMBIKAL_03603 1.4e-240 yfnA E amino acid
APMBIKAL_03604 8.1e-131 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
APMBIKAL_03605 4.6e-206 fsr P COG0477 Permeases of the major facilitator superfamily
APMBIKAL_03606 1e-189 yfnD M Nucleotide-diphospho-sugar transferase
APMBIKAL_03607 2.3e-223 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
APMBIKAL_03608 2.4e-180 yfnF M Nucleotide-diphospho-sugar transferase
APMBIKAL_03609 7.1e-172 yfnG 4.2.1.45 M dehydratase
APMBIKAL_03610 1e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
APMBIKAL_03611 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
APMBIKAL_03612 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
APMBIKAL_03613 3.6e-199 yetN S Protein of unknown function (DUF3900)
APMBIKAL_03614 5.2e-209 yetM CH FAD binding domain
APMBIKAL_03615 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
APMBIKAL_03616 2.3e-157 yetK EG EamA-like transporter family
APMBIKAL_03617 9.1e-105 yetJ S Belongs to the BI1 family
APMBIKAL_03618 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
APMBIKAL_03619 3.2e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
APMBIKAL_03620 2.2e-34
APMBIKAL_03621 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APMBIKAL_03622 3.7e-54 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
APMBIKAL_03623 8.8e-122 yetF S membrane
APMBIKAL_03624 4.2e-253 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
APMBIKAL_03625 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
APMBIKAL_03626 3.2e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
APMBIKAL_03627 1.3e-284 lplA G Bacterial extracellular solute-binding protein
APMBIKAL_03628 0.0 yetA
APMBIKAL_03629 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
APMBIKAL_03630 7.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
APMBIKAL_03631 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
APMBIKAL_03632 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
APMBIKAL_03633 2.4e-110 yesV S Protein of unknown function, DUF624
APMBIKAL_03634 6e-128 yesU S Domain of unknown function (DUF1961)
APMBIKAL_03635 1e-130 E GDSL-like Lipase/Acylhydrolase
APMBIKAL_03636 0.0 yesS K Transcriptional regulator
APMBIKAL_03637 1e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
APMBIKAL_03638 4.1e-164 yesQ P Binding-protein-dependent transport system inner membrane component
APMBIKAL_03639 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
APMBIKAL_03640 3.6e-246 yesO G Bacterial extracellular solute-binding protein
APMBIKAL_03641 4.7e-202 yesN K helix_turn_helix, arabinose operon control protein
APMBIKAL_03642 0.0 yesM 2.7.13.3 T Histidine kinase
APMBIKAL_03643 7.7e-101 yesL S Protein of unknown function, DUF624
APMBIKAL_03645 6e-102 yesJ K Acetyltransferase (GNAT) family
APMBIKAL_03646 5.2e-104 cotJC P Spore Coat
APMBIKAL_03647 1.5e-45 cotJB S CotJB protein
APMBIKAL_03648 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
APMBIKAL_03649 2.4e-153 yesF GM NAD(P)H-binding
APMBIKAL_03650 9.7e-82 yesE S SnoaL-like domain
APMBIKAL_03651 1.2e-103 dhaR3 K Transcriptional regulator
APMBIKAL_03653 9.4e-127 yeeN K transcriptional regulatory protein
APMBIKAL_03655 2.1e-213 S Tetratricopeptide repeat
APMBIKAL_03656 9.7e-49
APMBIKAL_03657 7e-26 3.4.24.40 CO amine dehydrogenase activity
APMBIKAL_03658 2e-128 3.4.24.40 CO amine dehydrogenase activity
APMBIKAL_03660 2.5e-100 L endonuclease activity
APMBIKAL_03662 0.0 L nucleic acid phosphodiester bond hydrolysis
APMBIKAL_03663 1.6e-82 S Protein of unknown function, DUF600
APMBIKAL_03664 6.2e-31 S Colicin immunity protein / pyocin immunity protein
APMBIKAL_03666 4.1e-100 S response regulator aspartate phosphatase
APMBIKAL_03668 0.0 K SIR2-like domain
APMBIKAL_03669 5e-20
APMBIKAL_03670 1.1e-248 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
APMBIKAL_03671 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
APMBIKAL_03672 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APMBIKAL_03673 1.3e-148 yerO K Transcriptional regulator
APMBIKAL_03674 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
APMBIKAL_03675 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
APMBIKAL_03676 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
APMBIKAL_03677 1.3e-263 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APMBIKAL_03678 1.6e-123 sapB S MgtC SapB transporter
APMBIKAL_03679 1e-195 yerI S homoserine kinase type II (protein kinase fold)
APMBIKAL_03680 3e-218 camS S COG4851 Protein involved in sex pheromone biosynthesis
APMBIKAL_03681 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
APMBIKAL_03682 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
APMBIKAL_03683 1.1e-124 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
APMBIKAL_03684 8.8e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
APMBIKAL_03685 4.8e-51 yerC S protein conserved in bacteria
APMBIKAL_03686 1.1e-189 yerB S Protein of unknown function (DUF3048) C-terminal domain
APMBIKAL_03687 0.0 yerA 3.5.4.2 F adenine deaminase
APMBIKAL_03688 5.4e-28 S Protein of unknown function (DUF2892)
APMBIKAL_03689 2.7e-225 yjeH E Amino acid permease
APMBIKAL_03690 1e-72 K helix_turn_helix ASNC type
APMBIKAL_03691 1.1e-234 purD 6.3.4.13 F Belongs to the GARS family
APMBIKAL_03692 6.6e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
APMBIKAL_03693 2.8e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
APMBIKAL_03694 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
APMBIKAL_03695 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
APMBIKAL_03696 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APMBIKAL_03697 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APMBIKAL_03698 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APMBIKAL_03699 4.1e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
APMBIKAL_03700 2.8e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
APMBIKAL_03701 1.1e-214 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
APMBIKAL_03702 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
APMBIKAL_03703 8e-28 yebG S NETI protein
APMBIKAL_03704 4e-93 yebE S UPF0316 protein
APMBIKAL_03706 2.3e-118 yebC M Membrane
APMBIKAL_03707 6e-212 pbuG S permease
APMBIKAL_03708 6.6e-244 S Domain of unknown function (DUF4179)
APMBIKAL_03709 3.9e-85 K Belongs to the sigma-70 factor family. ECF subfamily
APMBIKAL_03710 1.1e-305 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
APMBIKAL_03711 0.0 yebA E COG1305 Transglutaminase-like enzymes
APMBIKAL_03712 5.8e-222 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
APMBIKAL_03713 1.7e-176 yeaC S COG0714 MoxR-like ATPases
APMBIKAL_03714 2.4e-153 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
APMBIKAL_03715 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
APMBIKAL_03716 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
APMBIKAL_03717 1.1e-178 yeaA S Protein of unknown function (DUF4003)
APMBIKAL_03718 2.6e-157 ydjP I Alpha/beta hydrolase family
APMBIKAL_03719 1.4e-34 ydjO S Cold-inducible protein YdjO
APMBIKAL_03721 1.8e-155 ydjN U Involved in the tonB-independent uptake of proteins
APMBIKAL_03722 4.5e-64 ydjM M Lytic transglycolase
APMBIKAL_03723 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
APMBIKAL_03724 3.9e-257 iolT EGP Major facilitator Superfamily
APMBIKAL_03725 5.7e-194 S Ion transport 2 domain protein
APMBIKAL_03726 4.1e-149 ydjI S virion core protein (lumpy skin disease virus)
APMBIKAL_03727 1.4e-125 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
APMBIKAL_03728 9.8e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
APMBIKAL_03729 2.1e-112 pspA KT Phage shock protein A
APMBIKAL_03730 6.8e-173 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
APMBIKAL_03731 1.9e-253 gutA G MFS/sugar transport protein
APMBIKAL_03732 1.6e-199 gutB 1.1.1.14 E Dehydrogenase
APMBIKAL_03733 0.0 K NB-ARC domain
APMBIKAL_03734 2.2e-150 ydjC S Abhydrolase domain containing 18
APMBIKAL_03735 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
APMBIKAL_03736 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
APMBIKAL_03737 7.9e-129 ydiL S CAAX protease self-immunity
APMBIKAL_03738 2.9e-27 ydiK S Domain of unknown function (DUF4305)
APMBIKAL_03739 1.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
APMBIKAL_03740 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
APMBIKAL_03741 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
APMBIKAL_03742 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
APMBIKAL_03743 0.0 ydiF S ABC transporter
APMBIKAL_03744 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
APMBIKAL_03745 6.2e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
APMBIKAL_03746 2.7e-123 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
APMBIKAL_03747 3.5e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
APMBIKAL_03748 1.3e-179 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
APMBIKAL_03750 7.8e-08
APMBIKAL_03751 1.2e-18
APMBIKAL_03757 9.6e-105
APMBIKAL_03762 8.9e-198 L Belongs to the 'phage' integrase family
APMBIKAL_03763 1.6e-260 S DNA-sulfur modification-associated
APMBIKAL_03764 6e-177
APMBIKAL_03765 1.1e-33 K Transcriptional regulator
APMBIKAL_03770 7.2e-10 S YopX protein
APMBIKAL_03773 1.2e-65
APMBIKAL_03777 6.4e-11 S Protein of unknown function (DUF2815)
APMBIKAL_03781 3.7e-93 S Protein of unknown function (DUF1273)
APMBIKAL_03785 4.2e-52
APMBIKAL_03789 2.1e-146 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
APMBIKAL_03790 7.2e-129 yoqW S Belongs to the SOS response-associated peptidase family
APMBIKAL_03792 2.1e-09 L transposase activity
APMBIKAL_03794 3.2e-139 S Pfam:DUF867
APMBIKAL_03795 2.1e-211 M Parallel beta-helix repeats
APMBIKAL_03796 1.9e-95 M Parallel beta-helix repeats
APMBIKAL_03800 1.2e-155
APMBIKAL_03801 7.6e-180 L AAA domain
APMBIKAL_03802 1.2e-85
APMBIKAL_03803 1e-284 3.6.4.12 J DnaB-like helicase C terminal domain
APMBIKAL_03804 1.1e-222 L DNA primase activity
APMBIKAL_03805 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
APMBIKAL_03806 0.0 S Bacterial DNA polymerase III alpha subunit
APMBIKAL_03807 2.3e-112 DR0488 S protein conserved in bacteria
APMBIKAL_03812 2e-80 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
APMBIKAL_03814 9.2e-86 2.7.6.1 EF Phosphoribosyl synthetase-associated domain
APMBIKAL_03815 4.8e-202 nadV 2.4.2.12 H Nicotinate phosphoribosyltransferase (NAPRTase) family
APMBIKAL_03816 1.5e-64 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
APMBIKAL_03821 3.3e-13
APMBIKAL_03825 1.2e-25 S hydrolase activity
APMBIKAL_03836 9e-63 S NrdI Flavodoxin like
APMBIKAL_03837 2.8e-123 S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
APMBIKAL_03838 2.8e-73 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APMBIKAL_03839 6.6e-173 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APMBIKAL_03841 1.9e-181 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APMBIKAL_03842 8.9e-37 O Glutaredoxin
APMBIKAL_03843 8.1e-10
APMBIKAL_03844 2.7e-73 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
APMBIKAL_03848 2.1e-162 S Thymidylate synthase
APMBIKAL_03849 2.4e-21 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
APMBIKAL_03851 1.7e-84
APMBIKAL_03853 2.5e-30 sspB S spore protein
APMBIKAL_03854 1e-164 S Calcineurin-like phosphoesterase
APMBIKAL_03864 1.9e-10 K Cro/C1-type HTH DNA-binding domain
APMBIKAL_03865 1.5e-93 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
APMBIKAL_03867 1.2e-244 cisA2 L Recombinase
APMBIKAL_03868 8.7e-69 spoVK O stage V sporulation protein K
APMBIKAL_03869 3.6e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
APMBIKAL_03870 1.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
APMBIKAL_03871 4.3e-68 glnR K transcriptional
APMBIKAL_03872 7e-261 glnA 6.3.1.2 E glutamine synthetase
APMBIKAL_03875 1.7e-39
APMBIKAL_03876 1.8e-42 A Pre-toxin TG
APMBIKAL_03877 3e-11 A Pre-toxin TG
APMBIKAL_03878 6.4e-09 ywqJ S LXG domain of WXG superfamily
APMBIKAL_03879 3e-18 A Pre-toxin TG
APMBIKAL_03880 4.7e-87 A Pre-toxin TG
APMBIKAL_03881 2.7e-127 S Protein of unknown function (DUF1524)
APMBIKAL_03882 6.5e-10
APMBIKAL_03883 3.9e-31
APMBIKAL_03884 5.3e-70 Q Collagen triple helix repeat (20 copies)
APMBIKAL_03885 2.2e-93 M Glycosyltransferase like family
APMBIKAL_03886 7.6e-121 H Methionine biosynthesis protein MetW
APMBIKAL_03887 9.4e-142 M COG0463 Glycosyltransferases involved in cell wall biogenesis
APMBIKAL_03888 1.7e-217 sumf2 2.1.1.295 GT2,GT4 H N-terminal domain of galactosyltransferase
APMBIKAL_03889 4.4e-97 ynaD J Acetyltransferase (GNAT) domain
APMBIKAL_03891 2e-73 S CAAX protease self-immunity
APMBIKAL_03892 8.7e-81 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
APMBIKAL_03893 2.3e-254 xynT G MFS/sugar transport protein
APMBIKAL_03894 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
APMBIKAL_03895 7.3e-214 xylR GK ROK family
APMBIKAL_03896 1.3e-262 xylA 5.3.1.5 G Belongs to the xylose isomerase family
APMBIKAL_03897 5.6e-291 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
APMBIKAL_03898 6.4e-111 yokF 3.1.31.1 L RNA catabolic process
APMBIKAL_03899 5.5e-256 iolT EGP Major facilitator Superfamily
APMBIKAL_03900 1e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
APMBIKAL_03901 7.7e-82 yncE S Protein of unknown function (DUF2691)
APMBIKAL_03902 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
APMBIKAL_03903 5.2e-15
APMBIKAL_03906 3e-164 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
APMBIKAL_03908 1e-125 S Domain of unknown function, YrpD
APMBIKAL_03911 3.9e-24 tatA U protein secretion
APMBIKAL_03912 1.8e-71
APMBIKAL_03913 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
APMBIKAL_03916 3.9e-279 gerAA EG Spore germination protein
APMBIKAL_03917 3.8e-196 gerAB U Spore germination
APMBIKAL_03918 1.8e-218 gerLC S Spore germination protein
APMBIKAL_03919 2.8e-151 yndG S DoxX-like family
APMBIKAL_03920 1.6e-307 yndJ S YndJ-like protein
APMBIKAL_03923 1.5e-135 yndL S Replication protein
APMBIKAL_03924 6.4e-73 yndM S Protein of unknown function (DUF2512)
APMBIKAL_03925 4.9e-78 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
APMBIKAL_03926 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
APMBIKAL_03927 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
APMBIKAL_03928 2.9e-111 yneB L resolvase
APMBIKAL_03929 1.3e-32 ynzC S UPF0291 protein
APMBIKAL_03930 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
APMBIKAL_03931 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
APMBIKAL_03932 1.8e-28 yneF S UPF0154 protein
APMBIKAL_03933 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
APMBIKAL_03934 7.1e-127 ccdA O cytochrome c biogenesis protein
APMBIKAL_03935 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
APMBIKAL_03936 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
APMBIKAL_03937 4.2e-74 yneK S Protein of unknown function (DUF2621)
APMBIKAL_03938 8.5e-63 hspX O Spore coat protein
APMBIKAL_03939 3.9e-19 sspP S Belongs to the SspP family
APMBIKAL_03940 2.2e-14 sspO S Belongs to the SspO family
APMBIKAL_03941 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
APMBIKAL_03942 3.8e-90 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
APMBIKAL_03944 3.1e-08 sspN S Small acid-soluble spore protein N family
APMBIKAL_03945 1.5e-34 tlp S Belongs to the Tlp family
APMBIKAL_03946 2.7e-73 yneP S Thioesterase-like superfamily
APMBIKAL_03947 2.9e-53 yneQ
APMBIKAL_03948 4.1e-49 yneR S Belongs to the HesB IscA family
APMBIKAL_03949 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
APMBIKAL_03950 8.6e-69 yccU S CoA-binding protein
APMBIKAL_03951 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
APMBIKAL_03952 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
APMBIKAL_03953 2.3e-12
APMBIKAL_03954 1.3e-57 ynfC
APMBIKAL_03955 5.3e-251 agcS E Sodium alanine symporter
APMBIKAL_03956 5.8e-296 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
APMBIKAL_03958 6.9e-250 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
APMBIKAL_03959 5.6e-294 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
APMBIKAL_03960 2e-79 yngA S membrane
APMBIKAL_03961 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
APMBIKAL_03962 5.5e-104 yngC S membrane-associated protein
APMBIKAL_03963 1.2e-232 nrnB S phosphohydrolase (DHH superfamily)
APMBIKAL_03964 9.1e-289 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
APMBIKAL_03965 2.2e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
APMBIKAL_03966 8e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
APMBIKAL_03967 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
APMBIKAL_03968 8.6e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
APMBIKAL_03969 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
APMBIKAL_03970 4.1e-209 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
APMBIKAL_03971 1.1e-305 yngK T Glycosyl hydrolase-like 10
APMBIKAL_03972 4e-63 yngL S Protein of unknown function (DUF1360)
APMBIKAL_03973 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
APMBIKAL_03974 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APMBIKAL_03975 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APMBIKAL_03976 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APMBIKAL_03977 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APMBIKAL_03978 1.8e-37 yaaB S Domain of unknown function (DUF370)
APMBIKAL_03979 7e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
APMBIKAL_03980 2.4e-33 yaaA S S4 domain
APMBIKAL_03981 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
APMBIKAL_03982 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
APMBIKAL_03983 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
APMBIKAL_03984 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APMBIKAL_03985 6.5e-108 jag S single-stranded nucleic acid binding R3H
APMBIKAL_03986 3.7e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
APMBIKAL_03987 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
APMBIKAL_03988 4.1e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
APMBIKAL_03989 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
APMBIKAL_03990 2.5e-74 S Bacterial PH domain
APMBIKAL_03991 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
APMBIKAL_03992 4.6e-149 spo0J K Belongs to the ParB family
APMBIKAL_03993 1.6e-111 yyaC S Sporulation protein YyaC
APMBIKAL_03994 5.2e-176 yyaD S Membrane
APMBIKAL_03995 2.3e-33 yyzM S protein conserved in bacteria
APMBIKAL_03996 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
APMBIKAL_03997 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
APMBIKAL_03998 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
APMBIKAL_03999 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
APMBIKAL_04000 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
APMBIKAL_04001 5.8e-143 xth 3.1.11.2 L exodeoxyribonuclease III
APMBIKAL_04002 1.9e-60 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
APMBIKAL_04003 1.9e-52 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
APMBIKAL_04004 8.4e-66 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APMBIKAL_04005 2.8e-94 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
APMBIKAL_04006 1.8e-243 EGP Major facilitator superfamily
APMBIKAL_04007 8e-168 yyaK S CAAX protease self-immunity
APMBIKAL_04008 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
APMBIKAL_04009 1.2e-21 yyaL O Highly conserved protein containing a thioredoxin domain
APMBIKAL_04010 7.9e-99 S Protein of unknown function (DUF554)
APMBIKAL_04011 3.9e-113 K Bacterial transcription activator, effector binding domain
APMBIKAL_04012 5.7e-24 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
APMBIKAL_04014 1.8e-39 immA E Pfam:DUF955
APMBIKAL_04015 6.3e-34 yvaO K Transcriptional
APMBIKAL_04016 8.6e-11
APMBIKAL_04017 4.9e-28
APMBIKAL_04019 1.7e-63 S Bacterial protein of unknown function (DUF961)
APMBIKAL_04021 1.7e-222 ydcQ D Ftsk spoiiie family protein
APMBIKAL_04022 5.5e-200 nicK L Replication initiation factor
APMBIKAL_04023 4e-60
APMBIKAL_04026 3.1e-41 yddA
APMBIKAL_04028 1.5e-168 yddB S Conjugative transposon protein TcpC
APMBIKAL_04029 5.1e-40 yddC
APMBIKAL_04030 3.2e-92 yddD S TcpE family
APMBIKAL_04031 0.0 yddE S AAA-like domain
APMBIKAL_04032 4.8e-54 S Domain of unknown function (DUF1874)
APMBIKAL_04033 0.0 yddG S maturation of SSU-rRNA
APMBIKAL_04034 1.2e-185 yddH CBM50 M Lysozyme-like
APMBIKAL_04035 1.2e-80 yddI
APMBIKAL_04036 1.1e-44 S Domain of unknown function with cystatin-like fold (DUF4467)
APMBIKAL_04037 8e-123 S response regulator aspartate phosphatase
APMBIKAL_04038 4.3e-57 L Recombinase
APMBIKAL_04039 5.6e-29 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
APMBIKAL_04040 6.6e-246 tetL EGP Major facilitator Superfamily
APMBIKAL_04041 3.8e-107 yyaP 1.5.1.3 H RibD C-terminal domain
APMBIKAL_04042 3.5e-66 yyaQ S YjbR
APMBIKAL_04043 7.1e-92 yyaR K Acetyltransferase (GNAT) domain
APMBIKAL_04044 5.5e-96 yyaS S Membrane
APMBIKAL_04045 7.2e-69 yjcF S Acetyltransferase (GNAT) domain
APMBIKAL_04046 5.6e-77 yybA 2.3.1.57 K transcriptional
APMBIKAL_04047 1.1e-124 S Metallo-beta-lactamase superfamily
APMBIKAL_04048 9.5e-75 yybC
APMBIKAL_04049 2e-79 yjcF S Acetyltransferase (GNAT) domain
APMBIKAL_04050 1.1e-164 yybE K Transcriptional regulator
APMBIKAL_04051 2.3e-218 ynfM EGP Major facilitator Superfamily
APMBIKAL_04052 1.6e-122 yybG S Pentapeptide repeat-containing protein
APMBIKAL_04053 2.9e-66 yybH S SnoaL-like domain
APMBIKAL_04054 5.3e-123
APMBIKAL_04055 3.7e-110 K TipAS antibiotic-recognition domain
APMBIKAL_04056 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
APMBIKAL_04058 9.5e-61
APMBIKAL_04059 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
APMBIKAL_04060 1.7e-66 ydeP3 K Transcriptional regulator
APMBIKAL_04061 2.9e-63 cotF M Spore coat protein
APMBIKAL_04063 8.3e-160 yybS S membrane
APMBIKAL_04064 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
APMBIKAL_04065 2.2e-73 rplI J binds to the 23S rRNA
APMBIKAL_04066 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
APMBIKAL_04067 1.2e-219 yeaN P COG2807 Cyanate permease
APMBIKAL_04068 1.9e-15 yycC K YycC-like protein
APMBIKAL_04070 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
APMBIKAL_04071 1.2e-250 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
APMBIKAL_04072 7.5e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APMBIKAL_04073 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
APMBIKAL_04078 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APMBIKAL_04079 0.0 vicK 2.7.13.3 T Histidine kinase
APMBIKAL_04080 2.9e-257 yycH S protein conserved in bacteria
APMBIKAL_04081 1.8e-153 yycI S protein conserved in bacteria
APMBIKAL_04082 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
APMBIKAL_04083 8.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
APMBIKAL_04084 1.9e-33 S Peptidase propeptide and YPEB domain
APMBIKAL_04085 1.2e-73 S Peptidase propeptide and YPEB domain
APMBIKAL_04086 3.4e-94 K PFAM response regulator receiver
APMBIKAL_04087 1.8e-172 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
APMBIKAL_04088 4.4e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
APMBIKAL_04089 7.3e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
APMBIKAL_04090 9.7e-261 rocE E amino acid
APMBIKAL_04091 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
APMBIKAL_04093 3.8e-188 S aspartate phosphatase
APMBIKAL_04094 4.5e-85 yycN 2.3.1.128 K Acetyltransferase
APMBIKAL_04095 2.9e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
APMBIKAL_04096 6e-200 yycP
APMBIKAL_04097 1.7e-30 yycQ S Protein of unknown function (DUF2651)
APMBIKAL_04099 5.1e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
APMBIKAL_04100 7e-66
APMBIKAL_04101 1.1e-09 S YyzF-like protein
APMBIKAL_04102 2.3e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
APMBIKAL_04105 1.3e-126 2.7.7.49 L DNA polymerase
APMBIKAL_04107 9.3e-153 L RNA-directed DNA polymerase
APMBIKAL_04109 1.2e-41 S MazG-like family
APMBIKAL_04110 1.9e-247 L Uncharacterized conserved protein (DUF2075)
APMBIKAL_04111 0.0 L AAA domain
APMBIKAL_04112 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
APMBIKAL_04113 3.5e-109 prrC P ABC transporter
APMBIKAL_04114 1.6e-118 S ABC-2 family transporter protein
APMBIKAL_04115 7.6e-13
APMBIKAL_04116 4.4e-15
APMBIKAL_04117 2.6e-154
APMBIKAL_04118 5.2e-18 3.4.24.84 O PFAM Peptidase M48
APMBIKAL_04119 3e-273 L COG0210 Superfamily I DNA and RNA helicases
APMBIKAL_04120 2.1e-123 yydK K Transcriptional regulator
APMBIKAL_04121 1.4e-31 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
APMBIKAL_04122 1e-289 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
APMBIKAL_04123 1.9e-286 ahpF O Alkyl hydroperoxide reductase
APMBIKAL_04124 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
APMBIKAL_04125 1.9e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
APMBIKAL_04126 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
APMBIKAL_04127 1.6e-301 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
APMBIKAL_04128 7.3e-127 gntR K transcriptional
APMBIKAL_04129 9.5e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
APMBIKAL_04130 3.7e-193 yxaB GM Polysaccharide pyruvyl transferase
APMBIKAL_04131 6.5e-117 yxaC M effector of murein hydrolase
APMBIKAL_04132 5.2e-50 S LrgA family
APMBIKAL_04133 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
APMBIKAL_04134 5.2e-198 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
APMBIKAL_04135 4.6e-100 yxaF K Transcriptional regulator
APMBIKAL_04136 4.2e-197 yxaG 1.13.11.24 S AraC-like ligand binding domain
APMBIKAL_04137 3.5e-227 P Protein of unknown function (DUF418)
APMBIKAL_04138 1.1e-75 yxaI S membrane protein domain
APMBIKAL_04139 7.9e-65 S Family of unknown function (DUF5391)
APMBIKAL_04140 6.4e-91 S PQQ-like domain
APMBIKAL_04141 7.6e-214 yxaM U MFS_1 like family
APMBIKAL_04142 0.0 asnB 6.3.5.4 E Asparagine synthase
APMBIKAL_04143 1.1e-86 yxnB
APMBIKAL_04144 1.9e-43 S Coenzyme PQQ synthesis protein D (PqqD)
APMBIKAL_04145 1.3e-126 yxbB Q Met-10+ like-protein
APMBIKAL_04146 7e-95 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APMBIKAL_04147 3.4e-272 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
APMBIKAL_04148 1.5e-188 yoxA 5.1.3.3 G Aldose 1-epimerase
APMBIKAL_04149 2.3e-246 yoeA V MATE efflux family protein
APMBIKAL_04150 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
APMBIKAL_04152 2.2e-96 L Integrase
APMBIKAL_04153 5.1e-34 yoeD G Helix-turn-helix domain
APMBIKAL_04154 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
APMBIKAL_04155 1.2e-157 gltR1 K Transcriptional regulator
APMBIKAL_04156 1.6e-185 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
APMBIKAL_04157 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
APMBIKAL_04158 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
APMBIKAL_04159 7.8e-155 gltC K Transcriptional regulator
APMBIKAL_04160 7.8e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
APMBIKAL_04161 1.6e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APMBIKAL_04162 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
APMBIKAL_04163 2.4e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
APMBIKAL_04164 1.4e-39 yoxC S Bacterial protein of unknown function (DUF948)
APMBIKAL_04165 4.6e-124 yoxB
APMBIKAL_04166 3.9e-93 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
APMBIKAL_04167 1.4e-234 yoaB EGP Major facilitator Superfamily
APMBIKAL_04168 1.2e-277 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
APMBIKAL_04169 5.2e-184 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APMBIKAL_04170 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
APMBIKAL_04171 1.1e-33 yoaF
APMBIKAL_04172 6.5e-08 ywlA S Uncharacterised protein family (UPF0715)
APMBIKAL_04173 2.6e-13
APMBIKAL_04174 1.3e-37 S Protein of unknown function (DUF4025)
APMBIKAL_04175 7.4e-183 mcpU NT methyl-accepting chemotaxis protein
APMBIKAL_04176 2.4e-278 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
APMBIKAL_04177 1.2e-131 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
APMBIKAL_04178 2.3e-111 yoaK S Membrane
APMBIKAL_04179 8.1e-196 pelB 4.2.2.10, 4.2.2.2 G Amb_all
APMBIKAL_04180 3.5e-131 yoqW S Belongs to the SOS response-associated peptidase family
APMBIKAL_04183 5.5e-233 oxdC 4.1.1.2 G Oxalate decarboxylase
APMBIKAL_04185 1.9e-146 yoaP 3.1.3.18 K YoaP-like
APMBIKAL_04186 5.2e-42 yoaQ S Evidence 4 Homologs of previously reported genes of
APMBIKAL_04187 5e-87
APMBIKAL_04188 7.1e-172 yoaR V vancomycin resistance protein
APMBIKAL_04189 2.8e-74 yoaS S Protein of unknown function (DUF2975)
APMBIKAL_04190 1.6e-36 yozG K Transcriptional regulator
APMBIKAL_04191 6.3e-148 yoaT S Protein of unknown function (DUF817)
APMBIKAL_04192 3.3e-158 yoaU K LysR substrate binding domain
APMBIKAL_04193 4e-156 yijE EG EamA-like transporter family
APMBIKAL_04194 6.3e-78 yoaW
APMBIKAL_04195 3.8e-116 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
APMBIKAL_04196 1.2e-166 bla 3.5.2.6 V beta-lactamase
APMBIKAL_04199 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
APMBIKAL_04200 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
APMBIKAL_04201 8.8e-37 S TM2 domain
APMBIKAL_04202 2e-55 K Helix-turn-helix
APMBIKAL_04204 9.5e-50 FG Scavenger mRNA decapping enzyme C-term binding
APMBIKAL_04209 4.6e-11 ywlA S Uncharacterised protein family (UPF0715)
APMBIKAL_04213 4.1e-54 S Tetratricopeptide repeat
APMBIKAL_04214 5.2e-61 J tRNA cytidylyltransferase activity
APMBIKAL_04215 9e-21 xhlB S SPP1 phage holin
APMBIKAL_04216 2.1e-33 K sigma factor activity
APMBIKAL_04217 1.5e-144 msmR K AraC-like ligand binding domain
APMBIKAL_04218 4.4e-161 ybfH EG EamA-like transporter family
APMBIKAL_04220 3.8e-216 ybfB G COG0477 Permeases of the major facilitator superfamily
APMBIKAL_04221 1.1e-169 ybfA 3.4.15.5 K FR47-like protein
APMBIKAL_04222 1.5e-34 S Protein of unknown function (DUF2651)
APMBIKAL_04223 7.3e-258 glpT G -transporter
APMBIKAL_04224 4.8e-165 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
APMBIKAL_04225 1.8e-290 ybeC E amino acid
APMBIKAL_04226 4.9e-41 ybyB
APMBIKAL_04227 7.8e-246 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
APMBIKAL_04228 1.8e-150 ybxI 3.5.2.6 V beta-lactamase
APMBIKAL_04229 4.9e-30 ybxH S Family of unknown function (DUF5370)
APMBIKAL_04230 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
APMBIKAL_04231 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
APMBIKAL_04232 4.7e-216 ybdO S Domain of unknown function (DUF4885)
APMBIKAL_04233 4.3e-37 ybdN
APMBIKAL_04234 8.7e-102 ybdN
APMBIKAL_04235 2.7e-135 KLT Protein tyrosine kinase
APMBIKAL_04237 1.7e-171 T His Kinase A (phospho-acceptor) domain
APMBIKAL_04238 3.8e-122 T Transcriptional regulatory protein, C terminal
APMBIKAL_04239 9e-181 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
APMBIKAL_04240 3.7e-78 txn CO Thioredoxin-like
APMBIKAL_04241 8.6e-90 C HEAT repeats
APMBIKAL_04242 6.1e-247 skfF S ABC transporter
APMBIKAL_04243 4.8e-131 skfE V ABC transporter
APMBIKAL_04244 4.6e-277 V CAAX protease self-immunity
APMBIKAL_04245 1.2e-238 J 4Fe-4S single cluster domain
APMBIKAL_04247 1.4e-201 ybcL EGP Major facilitator Superfamily
APMBIKAL_04248 5.1e-50 ybzH K Helix-turn-helix domain
APMBIKAL_04250 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
APMBIKAL_04251 8.7e-47
APMBIKAL_04253 2e-94 can 4.2.1.1 P carbonic anhydrase
APMBIKAL_04254 0.0 ybcC S Belongs to the UPF0753 family
APMBIKAL_04255 7.5e-275 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
APMBIKAL_04256 1.2e-98 bcrC 3.6.1.27 I Bacitracin ABC transporter permease
APMBIKAL_04257 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
APMBIKAL_04258 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
APMBIKAL_04259 5.7e-224 ybbR S protein conserved in bacteria
APMBIKAL_04260 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
APMBIKAL_04261 4.1e-102 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
APMBIKAL_04262 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
APMBIKAL_04268 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
APMBIKAL_04269 1.9e-86 ybbJ J acetyltransferase
APMBIKAL_04270 1.5e-161 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
APMBIKAL_04271 2.5e-150 ybbH K transcriptional
APMBIKAL_04272 1.7e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APMBIKAL_04273 9.2e-253 yfeW 3.4.16.4 V Belongs to the UPF0214 family
APMBIKAL_04274 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
APMBIKAL_04275 2.1e-238 ybbC 3.2.1.52 S protein conserved in bacteria
APMBIKAL_04276 1.9e-305 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
APMBIKAL_04277 1.2e-164 feuA P Iron-uptake system-binding protein
APMBIKAL_04278 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APMBIKAL_04279 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APMBIKAL_04280 2.8e-137 ybbA S Putative esterase
APMBIKAL_04281 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
APMBIKAL_04283 1e-249 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
APMBIKAL_04285 2.9e-76 ctsR K Belongs to the CtsR family
APMBIKAL_04286 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
APMBIKAL_04287 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
APMBIKAL_04288 0.0 clpC O Belongs to the ClpA ClpB family
APMBIKAL_04289 6.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
APMBIKAL_04290 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
APMBIKAL_04291 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
APMBIKAL_04292 6.5e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
APMBIKAL_04293 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
APMBIKAL_04294 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
APMBIKAL_04295 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
APMBIKAL_04296 1.1e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
APMBIKAL_04297 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
APMBIKAL_04298 4.4e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APMBIKAL_04299 1.2e-88 yacP S RNA-binding protein containing a PIN domain
APMBIKAL_04300 4.4e-115 sigH K Belongs to the sigma-70 factor family
APMBIKAL_04301 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
APMBIKAL_04302 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
APMBIKAL_04303 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
APMBIKAL_04304 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
APMBIKAL_04305 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
APMBIKAL_04306 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
APMBIKAL_04307 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
APMBIKAL_04308 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APMBIKAL_04309 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APMBIKAL_04310 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
APMBIKAL_04311 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
APMBIKAL_04312 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
APMBIKAL_04313 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
APMBIKAL_04314 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
APMBIKAL_04315 3.3e-180 ybaC 3.4.11.5 S Alpha/beta hydrolase family
APMBIKAL_04316 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
APMBIKAL_04317 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
APMBIKAL_04318 3.9e-105 rplD J Forms part of the polypeptide exit tunnel
APMBIKAL_04319 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
APMBIKAL_04320 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
APMBIKAL_04321 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
APMBIKAL_04322 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
APMBIKAL_04323 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
APMBIKAL_04324 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
APMBIKAL_04325 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
APMBIKAL_04326 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
APMBIKAL_04327 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
APMBIKAL_04328 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
APMBIKAL_04329 2.3e-93 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
APMBIKAL_04330 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
APMBIKAL_04331 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
APMBIKAL_04332 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
APMBIKAL_04333 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
APMBIKAL_04334 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
APMBIKAL_04335 1.9e-23 rpmD J Ribosomal protein L30
APMBIKAL_04336 1.8e-72 rplO J binds to the 23S rRNA
APMBIKAL_04337 7.1e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
APMBIKAL_04338 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
APMBIKAL_04339 8.2e-142 map 3.4.11.18 E Methionine aminopeptidase
APMBIKAL_04340 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
APMBIKAL_04341 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
APMBIKAL_04342 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
APMBIKAL_04343 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
APMBIKAL_04344 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APMBIKAL_04345 3.6e-58 rplQ J Ribosomal protein L17
APMBIKAL_04346 5.6e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APMBIKAL_04347 3.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APMBIKAL_04348 1e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APMBIKAL_04349 2.6e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
APMBIKAL_04350 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
APMBIKAL_04351 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
APMBIKAL_04352 9e-144 ybaJ Q Methyltransferase domain
APMBIKAL_04353 9.7e-66 ybaK S Protein of unknown function (DUF2521)
APMBIKAL_04354 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
APMBIKAL_04355 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
APMBIKAL_04356 1.2e-84 gerD
APMBIKAL_04357 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
APMBIKAL_04358 2.7e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
APMBIKAL_04359 4.9e-30 csfB S Inhibitor of sigma-G Gin
APMBIKAL_04360 6.8e-102 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
APMBIKAL_04361 9.9e-203 yaaN P Belongs to the TelA family
APMBIKAL_04362 1.5e-272 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
APMBIKAL_04363 1.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
APMBIKAL_04364 2.2e-54 yaaQ S protein conserved in bacteria
APMBIKAL_04365 1.5e-71 yaaR S protein conserved in bacteria
APMBIKAL_04366 1.1e-181 holB 2.7.7.7 L DNA polymerase III
APMBIKAL_04367 2.1e-146 yaaT S stage 0 sporulation protein
APMBIKAL_04368 4.8e-31 yabA L Involved in initiation control of chromosome replication
APMBIKAL_04369 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
APMBIKAL_04370 1.5e-49 yazA L endonuclease containing a URI domain
APMBIKAL_04371 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
APMBIKAL_04372 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
APMBIKAL_04373 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
APMBIKAL_04374 1.2e-143 tatD L hydrolase, TatD
APMBIKAL_04375 2e-167 rpfB GH23 T protein conserved in bacteria
APMBIKAL_04376 4.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
APMBIKAL_04377 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
APMBIKAL_04378 6.2e-136 yabG S peptidase
APMBIKAL_04379 7.8e-39 veg S protein conserved in bacteria
APMBIKAL_04380 8.3e-27 sspF S DNA topological change
APMBIKAL_04381 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
APMBIKAL_04382 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
APMBIKAL_04383 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
APMBIKAL_04384 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
APMBIKAL_04385 6.2e-228 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
APMBIKAL_04386 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
APMBIKAL_04387 1.9e-96 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
APMBIKAL_04388 1.2e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
APMBIKAL_04389 2.4e-39 yabK S Peptide ABC transporter permease
APMBIKAL_04390 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
APMBIKAL_04391 1.5e-92 spoVT K stage V sporulation protein
APMBIKAL_04392 3.4e-278 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APMBIKAL_04393 4.7e-242 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
APMBIKAL_04394 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
APMBIKAL_04395 1.5e-49 yabP S Sporulation protein YabP
APMBIKAL_04396 2.5e-107 yabQ S spore cortex biosynthesis protein
APMBIKAL_04397 1.1e-44 divIC D Septum formation initiator
APMBIKAL_04398 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
APMBIKAL_04401 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
APMBIKAL_04402 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
APMBIKAL_04403 7.4e-186 KLT serine threonine protein kinase
APMBIKAL_04404 1.2e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
APMBIKAL_04405 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
APMBIKAL_04406 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
APMBIKAL_04407 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
APMBIKAL_04408 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
APMBIKAL_04409 1.7e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
APMBIKAL_04410 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
APMBIKAL_04411 2.2e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
APMBIKAL_04412 4.3e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
APMBIKAL_04413 8.7e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
APMBIKAL_04414 8.5e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
APMBIKAL_04415 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
APMBIKAL_04416 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
APMBIKAL_04417 4.1e-30 yazB K transcriptional
APMBIKAL_04418 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
APMBIKAL_04419 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
APMBIKAL_04420 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
APMBIKAL_04421 7.9e-32 yaaL S Protein of unknown function (DUF2508)
APMBIKAL_04422 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
APMBIKAL_04423 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
APMBIKAL_04424 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
APMBIKAL_04425 4.3e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
APMBIKAL_04426 1.9e-95 yaaI Q COG1335 Amidases related to nicotinamidase
APMBIKAL_04427 3.6e-214 yaaH M Glycoside Hydrolase Family
APMBIKAL_04428 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
APMBIKAL_04429 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
APMBIKAL_04430 1.3e-09
APMBIKAL_04431 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
APMBIKAL_04432 2.3e-107 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
APMBIKAL_04433 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
APMBIKAL_04434 1.2e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
APMBIKAL_04435 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
APMBIKAL_04436 1e-181 yaaC S YaaC-like Protein
APMBIKAL_04437 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APMBIKAL_04438 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APMBIKAL_04443 3.4e-39 S COG NOG14552 non supervised orthologous group
APMBIKAL_04448 2e-08
APMBIKAL_04455 2e-08

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)