ORF_ID e_value Gene_name EC_number CAZy COGs Description
JMCGKLLD_00001 9.1e-156 ylbM S Belongs to the UPF0348 family
JMCGKLLD_00002 7.6e-39 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
JMCGKLLD_00003 7.9e-44 yoeB S Addiction module toxin, Txe YoeB family
JMCGKLLD_00004 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
JMCGKLLD_00006 1.6e-103
JMCGKLLD_00009 1.1e-71 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
JMCGKLLD_00010 9.9e-132 ecsA V abc transporter atp-binding protein
JMCGKLLD_00011 3.2e-176 ecsB U Bacterial ABC transporter protein EcsB
JMCGKLLD_00012 2.7e-151 ytmP 2.7.1.89 M Phosphotransferase
JMCGKLLD_00013 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
JMCGKLLD_00015 3e-223 ytfP S Flavoprotein
JMCGKLLD_00016 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
JMCGKLLD_00017 8.2e-63 XK27_02560 S cog cog2151
JMCGKLLD_00018 2.6e-41 WQ51_02910 S Protein of unknown function, DUF536
JMCGKLLD_00019 6.4e-105 dnaQ 2.7.7.7 L DNA polymerase III
JMCGKLLD_00020 7.8e-121 K transcriptional regulator, MerR family
JMCGKLLD_00021 0.0 V ABC transporter (Permease
JMCGKLLD_00022 3.9e-125 V abc transporter atp-binding protein
JMCGKLLD_00024 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JMCGKLLD_00025 1.5e-49
JMCGKLLD_00026 2.1e-43
JMCGKLLD_00027 0.0 ctpE P E1-E2 ATPase
JMCGKLLD_00028 4.4e-59
JMCGKLLD_00029 5.5e-19 S Bacteriocin (Lactococcin_972)
JMCGKLLD_00030 0.0 S bacteriocin-associated integral membrane protein
JMCGKLLD_00031 2.3e-119 yujD V ABC transporter
JMCGKLLD_00032 1.2e-40 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase type II
JMCGKLLD_00033 2.8e-257 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JMCGKLLD_00034 2.7e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
JMCGKLLD_00035 1.3e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JMCGKLLD_00036 9.4e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
JMCGKLLD_00037 4.6e-100 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
JMCGKLLD_00038 3.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
JMCGKLLD_00039 1e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
JMCGKLLD_00041 3.5e-163 EGP Major facilitator Superfamily
JMCGKLLD_00042 1.8e-72 copY K negative regulation of transcription, DNA-templated
JMCGKLLD_00043 0.0 copA 3.6.3.54 P P-type ATPase
JMCGKLLD_00044 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
JMCGKLLD_00045 1.6e-191 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
JMCGKLLD_00046 3e-114 papP P ABC transporter (Permease
JMCGKLLD_00047 4.6e-107 P ABC transporter (Permease
JMCGKLLD_00048 1.5e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
JMCGKLLD_00049 9.7e-155 cjaA ET ABC transporter substrate-binding protein
JMCGKLLD_00053 4.1e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
JMCGKLLD_00054 1.6e-117 ywaF S Integral membrane protein (intg_mem_TP0381)
JMCGKLLD_00055 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JMCGKLLD_00056 4.7e-192 yjbB G Permeases of the major facilitator superfamily
JMCGKLLD_00057 1.4e-153 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
JMCGKLLD_00058 7.8e-100 thiT S Thiamine transporter
JMCGKLLD_00059 2.5e-62 yjqA S Bacterial PH domain
JMCGKLLD_00060 7.4e-153 corA P CorA-like protein
JMCGKLLD_00061 2.2e-245 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
JMCGKLLD_00062 4.6e-42 yazA L endonuclease containing a URI domain
JMCGKLLD_00063 1.6e-140 yabB 2.1.1.223 L Methyltransferase
JMCGKLLD_00064 1.8e-152 nodB3 G deacetylase
JMCGKLLD_00065 2.9e-142 plsC 2.3.1.51 I Acyltransferase
JMCGKLLD_00066 1.6e-91 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
JMCGKLLD_00067 0.0 comEC S Competence protein ComEC
JMCGKLLD_00068 2.6e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JMCGKLLD_00069 2.8e-99 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
JMCGKLLD_00070 3e-232 ytoI K transcriptional regulator containing CBS domains
JMCGKLLD_00071 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
JMCGKLLD_00072 3.7e-163 rbn E Belongs to the UPF0761 family
JMCGKLLD_00073 1.7e-85 ccl S cog cog4708
JMCGKLLD_00074 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JMCGKLLD_00075 1.5e-183 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
JMCGKLLD_00077 7e-173 yfjR K regulation of single-species biofilm formation
JMCGKLLD_00079 9.8e-72 S QueT transporter
JMCGKLLD_00080 9.1e-158 xth 3.1.11.2 L exodeoxyribonuclease III
JMCGKLLD_00082 1e-198 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JMCGKLLD_00083 2.9e-17 yjdB S Domain of unknown function (DUF4767)
JMCGKLLD_00084 3.9e-167 tehB 2.1.1.265 PQ tellurite resistance protein tehb
JMCGKLLD_00085 1.1e-189 O protein import
JMCGKLLD_00086 2.1e-129 agrA KT phosphorelay signal transduction system
JMCGKLLD_00087 1.3e-197 2.7.13.3 T GHKL domain
JMCGKLLD_00089 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
JMCGKLLD_00090 2.4e-37 ylqC L Belongs to the UPF0109 family
JMCGKLLD_00091 4.2e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
JMCGKLLD_00092 0.0 ydaO E amino acid
JMCGKLLD_00093 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
JMCGKLLD_00094 1e-145 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JMCGKLLD_00095 9e-294 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
JMCGKLLD_00096 4.1e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JMCGKLLD_00097 1.7e-82 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JMCGKLLD_00098 9.5e-169 murB 1.3.1.98 M cell wall formation
JMCGKLLD_00099 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
JMCGKLLD_00100 1.5e-138 potB P ABC-type spermidine putrescine transport system, permease component I
JMCGKLLD_00101 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
JMCGKLLD_00102 2.6e-205 potD P spermidine putrescine ABC transporter
JMCGKLLD_00103 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
JMCGKLLD_00104 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
JMCGKLLD_00105 2.3e-159 GK ROK family
JMCGKLLD_00106 2.5e-208 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JMCGKLLD_00107 5.1e-104 wecD M Acetyltransferase (GNAT) domain
JMCGKLLD_00108 7.4e-222 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JMCGKLLD_00109 5.4e-73 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
JMCGKLLD_00110 2.7e-58 arsC 1.20.4.1 P Belongs to the ArsC family
JMCGKLLD_00112 1.6e-187 femA 2.3.2.10, 2.3.2.16 V FemAB family
JMCGKLLD_00113 5.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JMCGKLLD_00114 1.8e-122 atpB C it plays a direct role in the translocation of protons across the membrane
JMCGKLLD_00115 9.5e-78 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JMCGKLLD_00116 1e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JMCGKLLD_00117 3.4e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JMCGKLLD_00118 4.8e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JMCGKLLD_00119 7.9e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JMCGKLLD_00120 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
JMCGKLLD_00121 5.1e-216 ftsW D Belongs to the SEDS family
JMCGKLLD_00122 1.6e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JMCGKLLD_00123 1.2e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
JMCGKLLD_00124 1.5e-228 murN 2.3.2.16 V FemAB family
JMCGKLLD_00125 1.2e-195 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
JMCGKLLD_00126 2.3e-66 yidA S hydrolases of the HAD superfamily
JMCGKLLD_00127 2.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JMCGKLLD_00128 5.9e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JMCGKLLD_00129 5.9e-160 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JMCGKLLD_00130 2.1e-120 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
JMCGKLLD_00131 3.8e-218 ywbD 2.1.1.191 J Methyltransferase
JMCGKLLD_00132 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
JMCGKLLD_00133 1.2e-25 WQ51_00785
JMCGKLLD_00134 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
JMCGKLLD_00135 8.7e-78 yueI S Protein of unknown function (DUF1694)
JMCGKLLD_00136 1.2e-200 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
JMCGKLLD_00137 7.2e-200 yyaQ S YjbR
JMCGKLLD_00138 1.9e-181 ccpA K Catabolite control protein A
JMCGKLLD_00139 1.7e-196 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
JMCGKLLD_00140 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
JMCGKLLD_00141 5.7e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JMCGKLLD_00142 1.9e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
JMCGKLLD_00143 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
JMCGKLLD_00144 2e-33 secG U Preprotein translocase subunit SecG
JMCGKLLD_00145 1e-221 mdtG EGP Major facilitator Superfamily
JMCGKLLD_00146 1.8e-99 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JMCGKLLD_00147 2e-149 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
JMCGKLLD_00148 2.2e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JMCGKLLD_00149 2e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
JMCGKLLD_00150 4.6e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JMCGKLLD_00151 4.1e-150 licT K antiterminator
JMCGKLLD_00152 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JMCGKLLD_00153 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
JMCGKLLD_00154 2.7e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JMCGKLLD_00155 5.1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JMCGKLLD_00156 1.3e-150 I Alpha/beta hydrolase family
JMCGKLLD_00157 6.6e-08
JMCGKLLD_00158 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
JMCGKLLD_00159 1.4e-78 feoA P FeoA domain protein
JMCGKLLD_00160 6.4e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
JMCGKLLD_00161 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
JMCGKLLD_00162 1e-34 ykuJ S protein conserved in bacteria
JMCGKLLD_00163 2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JMCGKLLD_00164 0.0 clpE O Belongs to the ClpA ClpB family
JMCGKLLD_00165 3e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
JMCGKLLD_00166 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
JMCGKLLD_00167 1e-176 S oxidoreductase
JMCGKLLD_00168 4.4e-118 M Pfam SNARE associated Golgi protein
JMCGKLLD_00169 1.9e-107 S Domain of Unknown Function with PDB structure (DUF3862)
JMCGKLLD_00172 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
JMCGKLLD_00175 4.8e-16 S Protein of unknown function (DUF2969)
JMCGKLLD_00176 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
JMCGKLLD_00177 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JMCGKLLD_00178 4.9e-11
JMCGKLLD_00180 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JMCGKLLD_00181 1.1e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
JMCGKLLD_00182 4.8e-13 L Helix-hairpin-helix DNA-binding motif class 1
JMCGKLLD_00183 2.2e-30 S Domain of unknown function (DUF1912)
JMCGKLLD_00184 5.5e-175 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
JMCGKLLD_00185 1.2e-250 mmuP E amino acid
JMCGKLLD_00186 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
JMCGKLLD_00187 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JMCGKLLD_00188 9.7e-22
JMCGKLLD_00189 5.8e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JMCGKLLD_00190 3.8e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JMCGKLLD_00191 1.5e-214 mvaS 2.3.3.10 I synthase
JMCGKLLD_00192 1.5e-228 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
JMCGKLLD_00193 3e-78 K hmm pf08876
JMCGKLLD_00194 5.2e-119 yqfA K protein, Hemolysin III
JMCGKLLD_00195 4.1e-29 pspC KT PspC domain protein
JMCGKLLD_00196 5.7e-205 S Protein of unknown function (DUF3114)
JMCGKLLD_00197 1.2e-169 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
JMCGKLLD_00198 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JMCGKLLD_00199 4e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
JMCGKLLD_00200 5.2e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
JMCGKLLD_00201 0.0 U protein secretion
JMCGKLLD_00202 3.4e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JMCGKLLD_00203 2.9e-25
JMCGKLLD_00204 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
JMCGKLLD_00205 3.2e-256 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JMCGKLLD_00206 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
JMCGKLLD_00207 2.1e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
JMCGKLLD_00208 2.3e-176 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
JMCGKLLD_00209 1e-168 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
JMCGKLLD_00210 3.9e-135 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
JMCGKLLD_00211 8.2e-102 GBS0088 J protein conserved in bacteria
JMCGKLLD_00212 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JMCGKLLD_00213 2e-83 comFC K competence protein
JMCGKLLD_00214 6.1e-249 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JMCGKLLD_00215 3.2e-107 yvyE 3.4.13.9 S YigZ family
JMCGKLLD_00216 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
JMCGKLLD_00217 3e-111 acuB S CBS domain
JMCGKLLD_00218 1.6e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
JMCGKLLD_00219 3.1e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
JMCGKLLD_00220 4.9e-139 livM E Belongs to the binding-protein-dependent transport system permease family
JMCGKLLD_00221 4.2e-145 livH E Belongs to the binding-protein-dependent transport system permease family
JMCGKLLD_00222 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
JMCGKLLD_00223 1.9e-46 ylbG S UPF0298 protein
JMCGKLLD_00224 1.4e-72 ylbF S Belongs to the UPF0342 family
JMCGKLLD_00225 1.1e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
JMCGKLLD_00226 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JMCGKLLD_00227 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
JMCGKLLD_00228 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
JMCGKLLD_00229 2.7e-224 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
JMCGKLLD_00230 1e-201 metB 2.5.1.48, 4.4.1.8 E cystathionine
JMCGKLLD_00231 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
JMCGKLLD_00232 1.1e-281 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
JMCGKLLD_00233 3e-273 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JMCGKLLD_00234 1.3e-99 yvdD 3.2.2.10 S Belongs to the LOG family
JMCGKLLD_00235 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JMCGKLLD_00236 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JMCGKLLD_00237 8e-42 ylxQ J ribosomal protein
JMCGKLLD_00238 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
JMCGKLLD_00239 2.4e-196 nusA K Participates in both transcription termination and antitermination
JMCGKLLD_00240 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
JMCGKLLD_00241 2e-212 brpA K Transcriptional
JMCGKLLD_00242 6e-91 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
JMCGKLLD_00243 4.2e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
JMCGKLLD_00244 1.6e-247 pbuO S permease
JMCGKLLD_00245 3.5e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
JMCGKLLD_00246 3.2e-138 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
JMCGKLLD_00247 2.4e-168 manL 2.7.1.191 G pts system
JMCGKLLD_00248 4.8e-132 manY G pts system
JMCGKLLD_00249 1.4e-159 manN G PTS system mannose fructose sorbose family IID component
JMCGKLLD_00250 7.7e-67 manO S Protein conserved in bacteria
JMCGKLLD_00251 4.9e-174 manL 2.7.1.191 G pts system
JMCGKLLD_00252 2.6e-117 manM G pts system
JMCGKLLD_00253 3.3e-169 manN G PTS system mannose fructose sorbose family IID component
JMCGKLLD_00254 2.5e-62 manO S protein conserved in bacteria
JMCGKLLD_00255 3.1e-229 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JMCGKLLD_00256 6.1e-114
JMCGKLLD_00257 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
JMCGKLLD_00258 1.5e-166 dnaI L Primosomal protein DnaI
JMCGKLLD_00259 1.6e-216 dnaB L Replication initiation and membrane attachment
JMCGKLLD_00260 1.4e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JMCGKLLD_00261 3.2e-281 T PhoQ Sensor
JMCGKLLD_00262 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JMCGKLLD_00263 1.8e-90 yceD K metal-binding, possibly nucleic acid-binding protein
JMCGKLLD_00264 1.5e-129 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
JMCGKLLD_00265 1.1e-237 P COG0168 Trk-type K transport systems, membrane components
JMCGKLLD_00266 4.2e-121 ktrA P COG0569 K transport systems, NAD-binding component
JMCGKLLD_00267 2e-149 cbiQ P cobalt transport
JMCGKLLD_00268 0.0 ykoD P abc transporter atp-binding protein
JMCGKLLD_00269 8e-94 S UPF0397 protein
JMCGKLLD_00270 2.1e-154 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
JMCGKLLD_00271 1.8e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
JMCGKLLD_00272 1.2e-99 metI P ABC transporter (Permease
JMCGKLLD_00273 3.7e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JMCGKLLD_00274 2e-263 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
JMCGKLLD_00275 1.4e-164 metQ M Belongs to the NlpA lipoprotein family
JMCGKLLD_00276 6.3e-138 ET ABC transporter substrate-binding protein
JMCGKLLD_00277 6.3e-131 cbiO P ABC transporter
JMCGKLLD_00278 1.1e-136 P cobalt transport protein
JMCGKLLD_00279 1.3e-176 cbiM P biosynthesis protein CbiM
JMCGKLLD_00280 1.8e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
JMCGKLLD_00281 4.7e-111 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
JMCGKLLD_00282 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
JMCGKLLD_00283 6.6e-78 ureE O enzyme active site formation
JMCGKLLD_00284 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
JMCGKLLD_00285 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
JMCGKLLD_00286 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
JMCGKLLD_00287 2.6e-94 ureI S AmiS/UreI family transporter
JMCGKLLD_00288 1.9e-240 S Domain of unknown function (DUF4173)
JMCGKLLD_00289 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
JMCGKLLD_00290 4.2e-116 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
JMCGKLLD_00291 1.7e-91 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JMCGKLLD_00292 6.4e-94 panT S ECF transporter, substrate-specific component
JMCGKLLD_00293 2.9e-91 panT S Psort location CytoplasmicMembrane, score
JMCGKLLD_00294 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
JMCGKLLD_00295 1.6e-165 metF 1.5.1.20 E reductase
JMCGKLLD_00296 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JMCGKLLD_00298 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
JMCGKLLD_00299 0.0 3.6.3.8 P cation transport ATPase
JMCGKLLD_00300 6.7e-245 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JMCGKLLD_00301 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JMCGKLLD_00302 1.8e-234 dltB M Membrane protein involved in D-alanine export
JMCGKLLD_00303 1.3e-298 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JMCGKLLD_00304 0.0 XK27_10035 V abc transporter atp-binding protein
JMCGKLLD_00305 5e-291 yfiB1 V abc transporter atp-binding protein
JMCGKLLD_00306 1.2e-98 pvaA M lytic transglycosylase activity
JMCGKLLD_00307 1.9e-178 ndpA S 37-kD nucleoid-associated bacterial protein
JMCGKLLD_00308 1e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JMCGKLLD_00309 1.3e-108 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
JMCGKLLD_00310 7e-150 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
JMCGKLLD_00311 3.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JMCGKLLD_00312 4.3e-109 tdk 2.7.1.21 F thymidine kinase
JMCGKLLD_00313 2.3e-187 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JMCGKLLD_00314 2.7e-151 gst O Glutathione S-transferase
JMCGKLLD_00315 1e-176 nrnA 3.1.13.3, 3.1.3.7 S domain protein
JMCGKLLD_00316 4.1e-175 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
JMCGKLLD_00317 4.4e-45 rpmE2 J 50S ribosomal protein L31
JMCGKLLD_00318 4.7e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
JMCGKLLD_00319 3.2e-162 ypuA S secreted protein
JMCGKLLD_00320 2.2e-72 yaeR E COG0346 Lactoylglutathione lyase and related lyases
JMCGKLLD_00321 7.9e-132 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
JMCGKLLD_00322 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JMCGKLLD_00323 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
JMCGKLLD_00324 1.4e-256 noxE P NADH oxidase
JMCGKLLD_00325 1.1e-294 yfmM S abc transporter atp-binding protein
JMCGKLLD_00326 4.3e-84 XK27_01265 S ECF-type riboflavin transporter, S component
JMCGKLLD_00327 3.1e-153 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
JMCGKLLD_00328 2.2e-85 S ECF-type riboflavin transporter, S component
JMCGKLLD_00330 2.9e-240 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JMCGKLLD_00331 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
JMCGKLLD_00333 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JMCGKLLD_00334 6e-91 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JMCGKLLD_00335 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JMCGKLLD_00336 2.9e-22 WQ51_00220 K Helix-turn-helix domain
JMCGKLLD_00337 6e-74 S Protein of unknown function (DUF3278)
JMCGKLLD_00338 0.0 smc D Required for chromosome condensation and partitioning
JMCGKLLD_00339 2.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
JMCGKLLD_00340 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JMCGKLLD_00341 3.6e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JMCGKLLD_00342 4.4e-123 alkD L Dna alkylation repair
JMCGKLLD_00343 9.4e-297 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JMCGKLLD_00344 7e-92 pat 2.3.1.183 M acetyltransferase
JMCGKLLD_00345 7.6e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JMCGKLLD_00346 7.1e-92 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JMCGKLLD_00347 1.1e-240 T PhoQ Sensor
JMCGKLLD_00348 1e-29 rpsT J Binds directly to 16S ribosomal RNA
JMCGKLLD_00349 5.5e-172 coaA 2.7.1.33 F Pantothenic acid kinase
JMCGKLLD_00350 1.7e-105 rsmC 2.1.1.172 J Methyltransferase small domain protein
JMCGKLLD_00351 7.3e-231 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
JMCGKLLD_00352 1.5e-110 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JMCGKLLD_00353 1.8e-66 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
JMCGKLLD_00354 1.7e-188 tcsA S membrane
JMCGKLLD_00355 2.1e-280 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
JMCGKLLD_00356 1.9e-176 yufP S Belongs to the binding-protein-dependent transport system permease family
JMCGKLLD_00357 1.2e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
JMCGKLLD_00358 5.8e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
JMCGKLLD_00359 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
JMCGKLLD_00360 1.1e-81 ypmB S Protein conserved in bacteria
JMCGKLLD_00361 8.3e-213 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
JMCGKLLD_00362 8.4e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
JMCGKLLD_00363 1.4e-18
JMCGKLLD_00364 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
JMCGKLLD_00365 1.2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JMCGKLLD_00366 1.8e-83 queD 4.1.2.50, 4.2.3.12 H synthase
JMCGKLLD_00367 1.2e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
JMCGKLLD_00368 2.5e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
JMCGKLLD_00369 9.1e-209 D nuclear chromosome segregation
JMCGKLLD_00370 1.4e-136 yejC S cyclic nucleotide-binding protein
JMCGKLLD_00371 7e-164 rapZ S Displays ATPase and GTPase activities
JMCGKLLD_00372 4.3e-183 ybhK S Required for morphogenesis under gluconeogenic growth conditions
JMCGKLLD_00373 5.7e-161 whiA K May be required for sporulation
JMCGKLLD_00374 1.9e-277 pepD E Dipeptidase
JMCGKLLD_00375 1.4e-147 XK27_10720 D peptidase activity
JMCGKLLD_00376 8.1e-293 adcA P Belongs to the bacterial solute-binding protein 9 family
JMCGKLLD_00377 2.6e-09
JMCGKLLD_00379 1.5e-170 yeiH S Membrane
JMCGKLLD_00380 1.3e-128 mur1 3.4.17.14, 3.5.1.28 NU muramidase
JMCGKLLD_00381 1.7e-165 cpsY K Transcriptional regulator
JMCGKLLD_00382 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
JMCGKLLD_00383 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
JMCGKLLD_00384 1.4e-105 artQ P ABC transporter (Permease
JMCGKLLD_00385 8.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
JMCGKLLD_00386 4.6e-157 aatB ET ABC transporter substrate-binding protein
JMCGKLLD_00387 1.3e-268 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JMCGKLLD_00388 6.4e-50
JMCGKLLD_00389 2.1e-45
JMCGKLLD_00390 4.2e-189 adhP 1.1.1.1 C alcohol dehydrogenase
JMCGKLLD_00391 1e-159 V AAA domain, putative AbiEii toxin, Type IV TA system
JMCGKLLD_00392 4.7e-57 S ABC-2 type transporter
JMCGKLLD_00393 2.3e-99
JMCGKLLD_00394 2.3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
JMCGKLLD_00395 1e-125 gntR1 K transcriptional
JMCGKLLD_00396 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JMCGKLLD_00397 1e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JMCGKLLD_00398 2.7e-86
JMCGKLLD_00399 2.7e-91 niaR S small molecule binding protein (contains 3H domain)
JMCGKLLD_00400 1.1e-127 K DNA-binding helix-turn-helix protein
JMCGKLLD_00401 2.1e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JMCGKLLD_00402 2.2e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JMCGKLLD_00403 3.6e-163 GK ROK family
JMCGKLLD_00404 1.7e-156 dprA LU DNA protecting protein DprA
JMCGKLLD_00405 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JMCGKLLD_00406 4.6e-83 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
JMCGKLLD_00407 1.3e-51 V ABC-2 family transporter protein
JMCGKLLD_00409 7.9e-146 S TraX protein
JMCGKLLD_00410 2.4e-121 KT Transcriptional regulatory protein, C terminal
JMCGKLLD_00411 0.0 glgE 2.3.1.12, 2.4.99.16, 3.2.1.1, 3.2.1.14 GH13,GH18 M Pilin isopeptide linkage domain protein
JMCGKLLD_00412 0.0 M Pilin isopeptide linkage domain protein
JMCGKLLD_00413 0.0 zmpB M signal peptide protein, YSIRK family
JMCGKLLD_00414 0.0 GM domain, Protein
JMCGKLLD_00415 6e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
JMCGKLLD_00416 0.0 sbcC L ATPase involved in DNA repair
JMCGKLLD_00417 9.9e-27 1.3.5.4 C reductase
JMCGKLLD_00418 3.4e-155 cat 2.3.1.28 S acetyltransferase'
JMCGKLLD_00419 0.0 M family 8
JMCGKLLD_00420 4.5e-147 epsH S acetyltransferase'
JMCGKLLD_00421 6.9e-239 M Glycosyltransferase, family 8
JMCGKLLD_00422 4.5e-288 tagE 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
JMCGKLLD_00423 1.5e-196 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
JMCGKLLD_00424 3.3e-186 nss M transferase activity, transferring glycosyl groups
JMCGKLLD_00425 1.9e-236 M Glycosyltransferase, family 8
JMCGKLLD_00426 1.3e-167 cpsJ M Glycosyltransferase group 2 family protein
JMCGKLLD_00427 0.0 M cog cog1442
JMCGKLLD_00428 6.8e-242 M family 8
JMCGKLLD_00429 5.1e-165 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
JMCGKLLD_00430 9.5e-310 asp1 S Accessory Sec system protein Asp1
JMCGKLLD_00431 1.5e-302 asp2 3.4.11.5 S Accessory Sec system protein Asp2
JMCGKLLD_00432 1.6e-68 asp3 S Accessory Sec system protein Asp3
JMCGKLLD_00433 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
JMCGKLLD_00434 3.9e-13 S Accessory secretory protein Sec Asp4
JMCGKLLD_00435 7e-12 S Accessory secretory protein Sec, Asp5
JMCGKLLD_00436 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JMCGKLLD_00437 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
JMCGKLLD_00438 1.7e-235 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
JMCGKLLD_00439 1.3e-238 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
JMCGKLLD_00441 3e-60 divIC D Septum formation initiator
JMCGKLLD_00442 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
JMCGKLLD_00443 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JMCGKLLD_00444 3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
JMCGKLLD_00445 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
JMCGKLLD_00446 1.1e-29 yyzM S Protein conserved in bacteria
JMCGKLLD_00447 7.2e-198 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
JMCGKLLD_00448 1.2e-255 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JMCGKLLD_00449 2.6e-135 parB K Belongs to the ParB family
JMCGKLLD_00450 9.2e-207 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
JMCGKLLD_00451 8e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JMCGKLLD_00452 6.2e-120 yoaK S Protein of unknown function (DUF1275)
JMCGKLLD_00456 0.0 XK27_10405 S Bacterial membrane protein YfhO
JMCGKLLD_00457 1.1e-305 ybiT S abc transporter atp-binding protein
JMCGKLLD_00458 7.1e-153 yvjA S membrane
JMCGKLLD_00459 1.2e-191 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
JMCGKLLD_00460 5.6e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
JMCGKLLD_00461 1.5e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JMCGKLLD_00462 8.9e-60 yaaA S S4 domain protein YaaA
JMCGKLLD_00463 4.8e-235 ymfF S Peptidase M16
JMCGKLLD_00464 2.8e-243 ymfH S Peptidase M16
JMCGKLLD_00465 3.3e-134 S sequence-specific DNA binding
JMCGKLLD_00466 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JMCGKLLD_00467 1.1e-150 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JMCGKLLD_00468 1.6e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JMCGKLLD_00469 1.7e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JMCGKLLD_00470 1.2e-60 lytE M LysM domain protein
JMCGKLLD_00471 5.8e-73 isaA GH23 M Immunodominant staphylococcal antigen A
JMCGKLLD_00472 0.0 S Bacterial membrane protein, YfhO
JMCGKLLD_00473 1.9e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
JMCGKLLD_00474 2.1e-98 yvbG U UPF0056 membrane protein
JMCGKLLD_00475 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
JMCGKLLD_00476 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
JMCGKLLD_00477 2.2e-73 rplI J binds to the 23S rRNA
JMCGKLLD_00478 1e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
JMCGKLLD_00479 1.8e-47 veg S Biofilm formation stimulator VEG
JMCGKLLD_00480 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JMCGKLLD_00481 1.9e-10
JMCGKLLD_00482 4.1e-54 ypaA M Membrane
JMCGKLLD_00483 9.9e-97 XK27_06935 K transcriptional regulator
JMCGKLLD_00484 5.6e-160 XK27_06930 V domain protein
JMCGKLLD_00485 3.6e-109 S Putative adhesin
JMCGKLLD_00486 2e-63 XK27_06920 S Protein of unknown function (DUF1700)
JMCGKLLD_00487 6.3e-54 K transcriptional regulator, PadR family
JMCGKLLD_00488 1.5e-117 nudL L hydrolase
JMCGKLLD_00492 8.4e-07
JMCGKLLD_00493 1.5e-259 amiA E ABC transporter, substrate-binding protein, family 5
JMCGKLLD_00494 2.7e-311 amiA E ABC transporter, substrate-binding protein, family 5
JMCGKLLD_00495 4.9e-279 amiC P ABC transporter (Permease
JMCGKLLD_00496 1.8e-167 amiD P ABC transporter (Permease
JMCGKLLD_00497 4.6e-202 oppD P Belongs to the ABC transporter superfamily
JMCGKLLD_00498 4.7e-171 oppF P Belongs to the ABC transporter superfamily
JMCGKLLD_00499 5.3e-131 V Psort location CytoplasmicMembrane, score
JMCGKLLD_00500 1.8e-119 skfE V abc transporter atp-binding protein
JMCGKLLD_00501 5.6e-62 yvoA_1 K Transcriptional
JMCGKLLD_00502 1.4e-147 supH S overlaps another CDS with the same product name
JMCGKLLD_00503 1.2e-146 XK27_02985 S overlaps another CDS with the same product name
JMCGKLLD_00504 6e-194 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
JMCGKLLD_00505 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
JMCGKLLD_00506 3.6e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
JMCGKLLD_00507 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JMCGKLLD_00508 2.8e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JMCGKLLD_00509 2.2e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JMCGKLLD_00510 4.8e-137 stp 3.1.3.16 T phosphatase
JMCGKLLD_00511 1.4e-302 prkC 2.7.11.1 KLT serine threonine protein kinase
JMCGKLLD_00512 3.1e-104 kcsA P Ion transport protein
JMCGKLLD_00513 8.6e-117 yvqF S Membrane
JMCGKLLD_00514 9.7e-170 vraS 2.7.13.3 T Histidine kinase
JMCGKLLD_00515 3.1e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JMCGKLLD_00518 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JMCGKLLD_00519 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
JMCGKLLD_00520 2.7e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
JMCGKLLD_00521 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
JMCGKLLD_00522 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
JMCGKLLD_00523 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JMCGKLLD_00524 2e-187 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JMCGKLLD_00525 5.7e-187 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
JMCGKLLD_00526 4e-286 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
JMCGKLLD_00527 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
JMCGKLLD_00528 1.4e-98 2.3.1.128 K Acetyltransferase GNAT Family
JMCGKLLD_00529 4.5e-288 S Protein of unknown function (DUF3114)
JMCGKLLD_00531 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
JMCGKLLD_00532 8.9e-249 V abc transporter atp-binding protein
JMCGKLLD_00533 6.1e-39 V abc transporter atp-binding protein
JMCGKLLD_00534 0.0 V abc transporter atp-binding protein
JMCGKLLD_00535 1.7e-194 XK27_10075 S abc transporter atp-binding protein
JMCGKLLD_00541 4.6e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
JMCGKLLD_00542 4.1e-107 S Domain of unknown function (DUF1803)
JMCGKLLD_00543 7.8e-102 ygaC J Belongs to the UPF0374 family
JMCGKLLD_00544 2e-138 recX 2.4.1.337 GT4 S Regulatory protein RecX
JMCGKLLD_00545 9.1e-248 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JMCGKLLD_00546 3e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
JMCGKLLD_00547 4.8e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
JMCGKLLD_00548 1.1e-113 S HAD hydrolase, family IA, variant 3
JMCGKLLD_00549 2.1e-140 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
JMCGKLLD_00550 5.2e-72 marR K Transcriptional regulator, MarR family
JMCGKLLD_00551 2.7e-169 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JMCGKLLD_00552 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
JMCGKLLD_00553 2e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
JMCGKLLD_00554 7.2e-164 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
JMCGKLLD_00555 6.2e-126 IQ reductase
JMCGKLLD_00556 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
JMCGKLLD_00557 5.6e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
JMCGKLLD_00558 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
JMCGKLLD_00559 5.4e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
JMCGKLLD_00560 2.3e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JMCGKLLD_00561 5.1e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
JMCGKLLD_00562 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
JMCGKLLD_00563 7.1e-207 rny D Endoribonuclease that initiates mRNA decay
JMCGKLLD_00564 1.4e-112 fruR K transcriptional
JMCGKLLD_00565 7.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
JMCGKLLD_00566 0.0 fruA 2.7.1.202 G phosphotransferase system
JMCGKLLD_00567 1.1e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JMCGKLLD_00568 1.2e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
JMCGKLLD_00570 1.6e-208 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
JMCGKLLD_00571 1.7e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JMCGKLLD_00572 3.5e-293 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
JMCGKLLD_00573 6.7e-256 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
JMCGKLLD_00574 5.8e-97 2.3.1.128 K acetyltransferase
JMCGKLLD_00575 3.4e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
JMCGKLLD_00576 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
JMCGKLLD_00577 4.5e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JMCGKLLD_00578 5e-63 WQ51_03320 S cog cog4835
JMCGKLLD_00579 2.9e-151 XK27_08360 S EDD domain protein, DegV family
JMCGKLLD_00580 6.7e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
JMCGKLLD_00581 2e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
JMCGKLLD_00582 0.0 yfmR S abc transporter atp-binding protein
JMCGKLLD_00583 2.3e-26 U response to pH
JMCGKLLD_00584 3e-131 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
JMCGKLLD_00585 1.6e-210 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
JMCGKLLD_00586 1.4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
JMCGKLLD_00587 4.3e-284 S Psort location CytoplasmicMembrane, score
JMCGKLLD_00588 4.6e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
JMCGKLLD_00589 8.8e-75 K DNA-binding transcription factor activity
JMCGKLLD_00590 2.5e-311 lmrA1 V abc transporter atp-binding protein
JMCGKLLD_00591 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JMCGKLLD_00592 2.9e-34 nrdH O Glutaredoxin
JMCGKLLD_00593 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JMCGKLLD_00594 2.5e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
JMCGKLLD_00595 3.9e-223 icd 1.1.1.42 C Isocitrate dehydrogenase
JMCGKLLD_00596 3e-38 ptsH G phosphocarrier protein Hpr
JMCGKLLD_00597 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JMCGKLLD_00598 1.1e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
JMCGKLLD_00599 6.1e-162 XK27_05670 S Putative esterase
JMCGKLLD_00600 2.7e-153 XK27_05675 S Esterase
JMCGKLLD_00601 9.9e-227 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
JMCGKLLD_00602 3.2e-179 yfmL 3.6.4.13 L DEAD DEAH box helicase
JMCGKLLD_00603 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
JMCGKLLD_00604 0.0 uup S abc transporter atp-binding protein
JMCGKLLD_00605 1.2e-29 MA20_06245 S yiaA/B two helix domain
JMCGKLLD_00606 2e-132 pip 1.11.1.10 S Alpha beta hydrolase
JMCGKLLD_00607 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JMCGKLLD_00608 2.3e-150 cobQ S glutamine amidotransferase
JMCGKLLD_00609 3.1e-256 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
JMCGKLLD_00610 1.5e-147 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JMCGKLLD_00611 6e-169 ybbR S Protein conserved in bacteria
JMCGKLLD_00612 9.7e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JMCGKLLD_00613 1.8e-66 gtrA S GtrA-like protein
JMCGKLLD_00614 2.6e-118 trmK 2.1.1.217 S SAM-dependent methyltransferase
JMCGKLLD_00615 2.9e-145 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JMCGKLLD_00616 8e-146 zupT P Mediates zinc uptake. May also transport other divalent cations
JMCGKLLD_00617 4.3e-200 yurR 1.4.5.1 E oxidoreductase
JMCGKLLD_00618 4.3e-258 S phospholipase Carboxylesterase
JMCGKLLD_00619 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JMCGKLLD_00620 2.7e-111 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
JMCGKLLD_00621 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
JMCGKLLD_00623 2.9e-30 KT response to antibiotic
JMCGKLLD_00624 5.9e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
JMCGKLLD_00625 2.4e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
JMCGKLLD_00626 1.2e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
JMCGKLLD_00627 1.2e-117 ylfI S tigr01906
JMCGKLLD_00628 1e-139 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
JMCGKLLD_00629 4.7e-147 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
JMCGKLLD_00630 5.4e-60 XK27_08085
JMCGKLLD_00631 5.9e-194 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JMCGKLLD_00632 4.1e-181 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JMCGKLLD_00633 8e-117 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
JMCGKLLD_00634 0.0 V Type III restriction enzyme, res subunit
JMCGKLLD_00635 2.3e-181 yclQ P ABC-type enterochelin transport system, periplasmic component
JMCGKLLD_00636 4e-232 dinF V Mate efflux family protein
JMCGKLLD_00637 7.9e-272 S Psort location CytoplasmicMembrane, score
JMCGKLLD_00638 2.1e-307 FbpA K RNA-binding protein homologous to eukaryotic snRNP
JMCGKLLD_00639 4e-134 S TraX protein
JMCGKLLD_00640 1e-93 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
JMCGKLLD_00641 2.9e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
JMCGKLLD_00642 4.5e-177 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
JMCGKLLD_00643 4.5e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
JMCGKLLD_00644 4.4e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JMCGKLLD_00645 1.6e-242 nylA 3.5.1.4 J Belongs to the amidase family
JMCGKLLD_00646 1.8e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
JMCGKLLD_00647 6.4e-82 yecS P ABC transporter (Permease
JMCGKLLD_00648 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
JMCGKLLD_00649 1.2e-171 bglC K Transcriptional regulator
JMCGKLLD_00650 4.3e-245 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JMCGKLLD_00651 2.8e-241 agcS E (Alanine) symporter
JMCGKLLD_00652 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
JMCGKLLD_00653 4.3e-239 metY 2.5.1.49 E o-acetylhomoserine
JMCGKLLD_00654 2.9e-27 S haloacid dehalogenase-like hydrolase
JMCGKLLD_00655 8.7e-60 S haloacid dehalogenase-like hydrolase
JMCGKLLD_00656 8.5e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JMCGKLLD_00657 1.3e-111 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
JMCGKLLD_00658 3e-34 M1-755 S Domain of unknown function (DUF1858)
JMCGKLLD_00659 2.2e-246 XK27_04775 S hemerythrin HHE cation binding domain
JMCGKLLD_00660 8.7e-148 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JMCGKLLD_00661 2.4e-172 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
JMCGKLLD_00662 1.6e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
JMCGKLLD_00663 1e-44 yktA S Belongs to the UPF0223 family
JMCGKLLD_00664 5.9e-143 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
JMCGKLLD_00665 4.1e-253 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
JMCGKLLD_00666 9e-156 pstS P phosphate
JMCGKLLD_00667 1.9e-156 pstC P probably responsible for the translocation of the substrate across the membrane
JMCGKLLD_00668 1.5e-155 pstA P phosphate transport system permease
JMCGKLLD_00669 1.5e-149 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JMCGKLLD_00670 3.5e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JMCGKLLD_00671 3.2e-113 phoU P Plays a role in the regulation of phosphate uptake
JMCGKLLD_00672 0.0 pepN 3.4.11.2 E aminopeptidase
JMCGKLLD_00673 4.6e-112 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
JMCGKLLD_00674 2.1e-215 yfnA E amino acid
JMCGKLLD_00675 1.1e-39 XK27_01300 P Protein conserved in bacteria
JMCGKLLD_00676 1.7e-117 S Carbohydrate-binding domain-containing protein Cthe_2159
JMCGKLLD_00677 1.4e-16 csbD S CsbD-like
JMCGKLLD_00678 1.5e-107 S Protein of unknown function (DUF421)
JMCGKLLD_00679 1.8e-59 S Protein of unknown function (DUF3290)
JMCGKLLD_00680 6e-182 manA 5.3.1.8 G mannose-6-phosphate isomerase
JMCGKLLD_00681 1.4e-232 brnQ E Component of the transport system for branched-chain amino acids
JMCGKLLD_00682 3.3e-123 T ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JMCGKLLD_00683 0.0 S Domain of unknown function DUF87
JMCGKLLD_00684 7.9e-31 T DNase/tRNase domain of colicin-like bacteriocin
JMCGKLLD_00685 3.3e-14
JMCGKLLD_00686 7.4e-180 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JMCGKLLD_00688 3.9e-243 norM V Multidrug efflux pump
JMCGKLLD_00689 4.7e-154 K sequence-specific DNA binding
JMCGKLLD_00690 2.8e-269 V (ABC) transporter
JMCGKLLD_00691 6.5e-224 pbuX F xanthine permease
JMCGKLLD_00692 4.3e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
JMCGKLLD_00693 5.4e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JMCGKLLD_00694 6.3e-150 T Histidine kinase
JMCGKLLD_00695 7.1e-133 macB2 V ABC transporter, ATP-binding protein
JMCGKLLD_00696 0.0 V ABC transporter (permease)
JMCGKLLD_00697 6.1e-93 XK27_05000 S metal cluster binding
JMCGKLLD_00698 1.5e-30 liaI KT membrane
JMCGKLLD_00699 5.4e-15 liaI KT membrane
JMCGKLLD_00700 6.9e-156 XK27_09825 V abc transporter atp-binding protein
JMCGKLLD_00701 3.1e-117 yvfS V Transporter
JMCGKLLD_00702 5.2e-83 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
JMCGKLLD_00703 8.7e-165 yocS S Transporter
JMCGKLLD_00706 2.8e-157 XK27_09825 V 'abc transporter, ATP-binding protein
JMCGKLLD_00707 5.3e-133 yvfS V ABC-2 type transporter
JMCGKLLD_00708 1.3e-191 desK 2.7.13.3 T Histidine kinase
JMCGKLLD_00709 1.5e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JMCGKLLD_00710 3.2e-201 S Protein of unknown function DUF262
JMCGKLLD_00711 1.3e-123 S Protein of unknown function DUF262
JMCGKLLD_00712 3.5e-18 3.2.1.51 GH95 U LPXTG cell wall anchor motif
JMCGKLLD_00713 1.9e-118 K Helix-turn-helix domain, rpiR family
JMCGKLLD_00714 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
JMCGKLLD_00715 0.0 3.5.1.28 M domain protein
JMCGKLLD_00716 5.9e-140 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
JMCGKLLD_00717 2.8e-87 maa 2.3.1.79 GK Maltose O-acetyltransferase
JMCGKLLD_00718 1.6e-67 rmaI K Transcriptional regulator, MarR family
JMCGKLLD_00719 1.7e-241 EGP Major facilitator Superfamily
JMCGKLLD_00720 1.3e-134 XK27_00785 S CAAX protease self-immunity
JMCGKLLD_00722 0.0 S dextransucrase activity
JMCGKLLD_00723 0.0 S dextransucrase activity
JMCGKLLD_00724 1.7e-303 S dextransucrase activity
JMCGKLLD_00725 0.0 M Putative cell wall binding repeat
JMCGKLLD_00726 5.2e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JMCGKLLD_00727 4.9e-105 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JMCGKLLD_00728 0.0 S dextransucrase activity
JMCGKLLD_00729 1.6e-240 tcdB S dextransucrase activity
JMCGKLLD_00730 0.0 M Putative cell wall binding repeat
JMCGKLLD_00731 1.7e-38 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JMCGKLLD_00732 0.0 srlM 2.7.1.202 GKT Mga helix-turn-helix domain
JMCGKLLD_00733 1.9e-86 gutM K Glucitol operon activator protein (GutM)
JMCGKLLD_00734 1e-96 srlA G PTS system glucitol sorbitol-specific
JMCGKLLD_00735 3.8e-179 srlE 2.7.1.198 G PTS sorbitol transporter subunit IIB
JMCGKLLD_00736 4.2e-59 srlB 2.7.1.198 G sorbitol-specific, IIA component
JMCGKLLD_00737 9.2e-59 L MULE transposase domain
JMCGKLLD_00738 1.1e-108 L Transposase IS116 IS110 IS902
JMCGKLLD_00739 1.3e-305 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
JMCGKLLD_00740 2.2e-219 L the current gene model (or a revised gene model) may contain a frame shift
JMCGKLLD_00741 1.4e-153 Z012_04635 K sequence-specific DNA binding
JMCGKLLD_00742 1.1e-276 V ABC transporter
JMCGKLLD_00743 6.1e-126 yeeN K transcriptional regulatory protein
JMCGKLLD_00744 7.7e-47 yajC U protein transport
JMCGKLLD_00745 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JMCGKLLD_00746 9.3e-144 cdsA 2.7.7.41 S Belongs to the CDS family
JMCGKLLD_00747 4.7e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
JMCGKLLD_00748 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
JMCGKLLD_00749 0.0 WQ51_06230 S ABC transporter
JMCGKLLD_00750 1.4e-142 cmpC S abc transporter atp-binding protein
JMCGKLLD_00751 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JMCGKLLD_00752 3.4e-286 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
JMCGKLLD_00754 3.2e-44
JMCGKLLD_00755 7.6e-55 S TM2 domain
JMCGKLLD_00756 4.7e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JMCGKLLD_00757 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JMCGKLLD_00758 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
JMCGKLLD_00759 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
JMCGKLLD_00760 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
JMCGKLLD_00761 1.3e-71 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
JMCGKLLD_00762 1.1e-144 cof S Sucrose-6F-phosphate phosphohydrolase
JMCGKLLD_00763 5.9e-135 glcR K transcriptional regulator (DeoR family)
JMCGKLLD_00764 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
JMCGKLLD_00765 1.6e-75 S Domain of unknown function (DUF4352)
JMCGKLLD_00766 2e-129 cbiO P ABC transporter
JMCGKLLD_00767 1.2e-130 P Cobalt transport protein
JMCGKLLD_00768 7.1e-102 nikMN P PDGLE domain
JMCGKLLD_00771 2.7e-185 lplA 6.3.1.20 H Lipoate-protein ligase
JMCGKLLD_00773 1.5e-27
JMCGKLLD_00774 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
JMCGKLLD_00775 6.6e-300 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
JMCGKLLD_00776 7.9e-156 malR K Transcriptional regulator
JMCGKLLD_00777 3.9e-229 malX G ABC transporter
JMCGKLLD_00778 8.2e-249 malF P ABC transporter (Permease
JMCGKLLD_00779 9.8e-152 malG P ABC transporter (Permease
JMCGKLLD_00780 1.4e-212 msmX P Belongs to the ABC transporter superfamily
JMCGKLLD_00781 3e-24 tatA U protein secretion
JMCGKLLD_00782 1.4e-119 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JMCGKLLD_00783 6.1e-286 ywbL P COG0672 High-affinity Fe2 Pb2 permease
JMCGKLLD_00784 9e-231 ycdB P peroxidase
JMCGKLLD_00785 4.9e-146 ycdO P periplasmic lipoprotein involved in iron transport
JMCGKLLD_00786 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
JMCGKLLD_00787 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
JMCGKLLD_00788 3e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
JMCGKLLD_00789 1.1e-223 G COG0457 FOG TPR repeat
JMCGKLLD_00790 4.3e-177 yubA S permease
JMCGKLLD_00791 1.9e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
JMCGKLLD_00792 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
JMCGKLLD_00793 3.2e-124 ftsE D cell division ATP-binding protein FtsE
JMCGKLLD_00794 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JMCGKLLD_00795 3.3e-200 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JMCGKLLD_00796 1.1e-155 yjjH S Calcineurin-like phosphoesterase
JMCGKLLD_00797 3.1e-133 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
JMCGKLLD_00798 0.0 pacL 3.6.3.8 P cation transport ATPase
JMCGKLLD_00799 5.3e-68 ywiB S Domain of unknown function (DUF1934)
JMCGKLLD_00800 8.4e-142 XK27_00120 2.4.2.3 F Phosphorylase superfamily
JMCGKLLD_00801 2.9e-51 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
JMCGKLLD_00802 4.5e-94 cppA E CppA N-terminal
JMCGKLLD_00803 1.6e-179 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
JMCGKLLD_00805 2.8e-76 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JMCGKLLD_00806 1.6e-148 cah 4.2.1.1 P carbonic anhydrase
JMCGKLLD_00807 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
JMCGKLLD_00809 0.0 pflB 2.3.1.54 C formate acetyltransferase'
JMCGKLLD_00810 9.5e-203 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JMCGKLLD_00811 3.6e-35
JMCGKLLD_00812 3.3e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
JMCGKLLD_00813 6.1e-163 yxeN P ABC transporter (Permease
JMCGKLLD_00814 1.4e-130 tcyN 3.6.3.21 E abc transporter atp-binding protein
JMCGKLLD_00815 5e-10 S Protein of unknown function (DUF4059)
JMCGKLLD_00816 1.7e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
JMCGKLLD_00817 1.5e-92 rsmD 2.1.1.171 L Methyltransferase
JMCGKLLD_00818 1.3e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JMCGKLLD_00819 4.2e-187 ylbL T Belongs to the peptidase S16 family
JMCGKLLD_00820 3.2e-183 yhcC S radical SAM protein
JMCGKLLD_00821 2.7e-97 ytqB J (SAM)-dependent
JMCGKLLD_00823 0.0 yjcE P NhaP-type Na H and K H antiporters
JMCGKLLD_00824 2.1e-143 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
JMCGKLLD_00825 9.9e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
JMCGKLLD_00826 5.2e-08 MU outer membrane autotransporter barrel domain protein
JMCGKLLD_00827 3.9e-158 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JMCGKLLD_00829 9e-75 XK27_03180 T universal stress protein
JMCGKLLD_00830 6.9e-239 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
JMCGKLLD_00831 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JMCGKLLD_00832 2.2e-99 pncA Q isochorismatase
JMCGKLLD_00833 4e-294 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JMCGKLLD_00834 6.9e-41 tagE 2.4.1.52 GT4 M transferase activity, transferring glycosyl groups
JMCGKLLD_00835 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JMCGKLLD_00836 9.1e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
JMCGKLLD_00837 1e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JMCGKLLD_00838 8.4e-27 L Transposase
JMCGKLLD_00839 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
JMCGKLLD_00840 6e-08 uvrX 2.7.7.7 L impB/mucB/samB family
JMCGKLLD_00841 8.7e-254 cycA E permease
JMCGKLLD_00842 5e-38 ynzC S UPF0291 protein
JMCGKLLD_00843 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
JMCGKLLD_00844 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
JMCGKLLD_00845 9.6e-220 S membrane
JMCGKLLD_00846 9.5e-214 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
JMCGKLLD_00847 3.8e-293 nptA P COG1283 Na phosphate symporter
JMCGKLLD_00848 1e-113 3.4.17.14, 3.5.1.28 NU amidase activity
JMCGKLLD_00849 3.1e-82 S Bacterial inner membrane protein
JMCGKLLD_00850 7.4e-144 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
JMCGKLLD_00851 2.1e-104 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
JMCGKLLD_00852 1.5e-30 glnB K Belongs to the P(II) protein family
JMCGKLLD_00853 2.5e-228 amt P Ammonium Transporter
JMCGKLLD_00854 2.8e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JMCGKLLD_00855 1.2e-54 yabA L Involved in initiation control of chromosome replication
JMCGKLLD_00856 8.9e-134 yaaT S stage 0 sporulation protein
JMCGKLLD_00857 1.3e-159 holB 2.7.7.7 L dna polymerase iii
JMCGKLLD_00858 2.4e-110 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JMCGKLLD_00859 7.2e-53
JMCGKLLD_00860 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
JMCGKLLD_00861 6.3e-128 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
JMCGKLLD_00862 8.8e-119 sdaAB 4.3.1.17 E L-serine dehydratase
JMCGKLLD_00863 3.4e-147 sdaAA 4.3.1.17 E L-serine dehydratase
JMCGKLLD_00864 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
JMCGKLLD_00865 1.9e-133 L Integrase
JMCGKLLD_00866 1.6e-202 S Protein of unknown function DUF262
JMCGKLLD_00867 2.1e-151 S Protein of unknown function DUF262
JMCGKLLD_00868 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
JMCGKLLD_00869 1.1e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JMCGKLLD_00870 2.7e-182 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JMCGKLLD_00871 1.3e-125 dnaD
JMCGKLLD_00872 1.7e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JMCGKLLD_00873 7.9e-07 KT response to antibiotic
JMCGKLLD_00874 8.6e-235 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JMCGKLLD_00875 4.6e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JMCGKLLD_00876 1.3e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JMCGKLLD_00877 2.2e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
JMCGKLLD_00878 2.8e-73 argR K Regulates arginine biosynthesis genes
JMCGKLLD_00879 9.3e-303 recN L May be involved in recombinational repair of damaged DNA
JMCGKLLD_00880 2e-144 DegV S DegV family
JMCGKLLD_00881 4.9e-162 ypmR E COG2755 Lysophospholipase L1 and related esterases
JMCGKLLD_00882 1.8e-96 ypmS S Protein conserved in bacteria
JMCGKLLD_00883 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
JMCGKLLD_00885 4.4e-177 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
JMCGKLLD_00886 2.1e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JMCGKLLD_00887 4.9e-290 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JMCGKLLD_00888 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
JMCGKLLD_00889 1.2e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JMCGKLLD_00890 1.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JMCGKLLD_00891 0.0 dnaE 2.7.7.7 L DNA polymerase
JMCGKLLD_00892 4.6e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
JMCGKLLD_00893 2.7e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
JMCGKLLD_00894 2.4e-103 L Phage integrase family
JMCGKLLD_00896 1.6e-21 E Zn peptidase
JMCGKLLD_00899 8.1e-50 S protein disulfide oxidoreductase activity
JMCGKLLD_00903 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JMCGKLLD_00904 4.3e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
JMCGKLLD_00905 8.9e-95 ypsA S Belongs to the UPF0398 family
JMCGKLLD_00906 1.1e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
JMCGKLLD_00907 1.3e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
JMCGKLLD_00908 1.5e-278 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
JMCGKLLD_00909 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
JMCGKLLD_00910 9.6e-23
JMCGKLLD_00911 4.7e-257 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
JMCGKLLD_00912 4.1e-89 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
JMCGKLLD_00913 1.3e-303 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JMCGKLLD_00914 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
JMCGKLLD_00915 3.4e-166 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JMCGKLLD_00916 9.2e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
JMCGKLLD_00917 2.1e-129 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JMCGKLLD_00918 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
JMCGKLLD_00919 2e-102 ybhL S Belongs to the BI1 family
JMCGKLLD_00920 2.4e-12 ycdA S Domain of unknown function (DUF4352)
JMCGKLLD_00921 2.1e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
JMCGKLLD_00922 1.4e-90 K transcriptional regulator
JMCGKLLD_00923 1.6e-36 yneF S UPF0154 protein
JMCGKLLD_00924 3.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
JMCGKLLD_00925 2.3e-184 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JMCGKLLD_00926 1.1e-97 XK27_09740 S Phosphoesterase
JMCGKLLD_00927 8.3e-87 ykuL S CBS domain
JMCGKLLD_00928 5e-134 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
JMCGKLLD_00929 4.5e-121 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JMCGKLLD_00930 3.8e-94 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JMCGKLLD_00931 4.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JMCGKLLD_00932 1.4e-13 yidD M Could be involved in insertion of integral membrane proteins into the membrane
JMCGKLLD_00933 4.2e-259 trkH P Cation transport protein
JMCGKLLD_00934 1e-246 trkA P Potassium transporter peripheral membrane component
JMCGKLLD_00935 5.1e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
JMCGKLLD_00936 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JMCGKLLD_00937 2.8e-106 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
JMCGKLLD_00938 6.6e-82 L Transposase
JMCGKLLD_00940 1.6e-137 agrA KT response regulator
JMCGKLLD_00941 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
JMCGKLLD_00943 1.2e-09
JMCGKLLD_00944 6.1e-64 K sequence-specific DNA binding
JMCGKLLD_00945 5.2e-77 L COG1943 Transposase and inactivated derivatives
JMCGKLLD_00947 1.7e-134 agrA KT Response regulator of the LytR AlgR family
JMCGKLLD_00948 1.8e-232 2.7.13.3 T GHKL domain
JMCGKLLD_00949 1.1e-119
JMCGKLLD_00950 1.2e-115 V ATPases associated with a variety of cellular activities
JMCGKLLD_00959 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JMCGKLLD_00960 3e-84 yxjI S LURP-one-related
JMCGKLLD_00961 7.8e-168 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
JMCGKLLD_00962 3e-119 yrrM 2.1.1.104 S O-Methyltransferase
JMCGKLLD_00963 1.2e-214 oxlT P COG0477 Permeases of the major facilitator superfamily
JMCGKLLD_00964 0.0 pepF E oligoendopeptidase F
JMCGKLLD_00965 1.8e-181 coiA 3.6.4.12 S Competence protein
JMCGKLLD_00966 5.2e-78 L transposition
JMCGKLLD_00967 3.7e-54 insK L Integrase core domain protein
JMCGKLLD_00968 8.7e-104 S CHAP domain
JMCGKLLD_00969 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
JMCGKLLD_00970 2.7e-272 glnP P ABC transporter
JMCGKLLD_00971 2.2e-123 glnQ E abc transporter atp-binding protein
JMCGKLLD_00972 2.7e-184 D nuclear chromosome segregation
JMCGKLLD_00973 2.8e-84 V VanZ like family
JMCGKLLD_00974 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JMCGKLLD_00975 7.6e-195 yhjX P Major Facilitator
JMCGKLLD_00976 4.9e-111 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
JMCGKLLD_00977 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
JMCGKLLD_00978 8.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JMCGKLLD_00979 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
JMCGKLLD_00980 3.7e-141 L Integrase core domain protein
JMCGKLLD_00981 2.9e-122 L Helix-turn-helix domain
JMCGKLLD_00982 2.2e-73 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
JMCGKLLD_00983 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JMCGKLLD_00984 5.9e-82 nrdI F Belongs to the NrdI family
JMCGKLLD_00985 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
JMCGKLLD_00986 2.6e-132 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
JMCGKLLD_00987 2e-177 prmA J Ribosomal protein L11 methyltransferase
JMCGKLLD_00988 4.9e-76 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
JMCGKLLD_00989 3.8e-84 XK27_03960 S Protein of unknown function (DUF3013)
JMCGKLLD_00990 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
JMCGKLLD_00991 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
JMCGKLLD_00992 8.9e-229 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
JMCGKLLD_00993 3.1e-139 ykuT M mechanosensitive ion channel
JMCGKLLD_00994 2.3e-87 sigH K DNA-templated transcription, initiation
JMCGKLLD_00996 1.5e-83 XK27_10475 S oxidoreductase
JMCGKLLD_00997 3.8e-196 gldA 1.1.1.6 C glycerol dehydrogenase
JMCGKLLD_00999 5e-284 XK27_07020 S Belongs to the UPF0371 family
JMCGKLLD_01000 1.4e-210 vex1 V Efflux ABC transporter, permease protein
JMCGKLLD_01001 1.9e-107 vex2 V abc transporter atp-binding protein
JMCGKLLD_01002 6e-239 vex3 V Efflux ABC transporter, permease protein
JMCGKLLD_01003 6.3e-114 K Response regulator receiver domain protein
JMCGKLLD_01004 1.2e-220 vncS 2.7.13.3 T Histidine kinase
JMCGKLLD_01005 2.1e-307 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
JMCGKLLD_01006 1.2e-151 galR K Transcriptional regulator
JMCGKLLD_01007 5.3e-220 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JMCGKLLD_01008 5.5e-286 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
JMCGKLLD_01009 2.1e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JMCGKLLD_01010 1.4e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
JMCGKLLD_01011 0.0 lacS G transporter
JMCGKLLD_01012 0.0 lacL 3.2.1.23 G -beta-galactosidase
JMCGKLLD_01013 3.2e-209 S Tetratricopeptide repeat
JMCGKLLD_01014 8.4e-159 yvgN C reductase
JMCGKLLD_01015 4.2e-30 XK27_10490
JMCGKLLD_01016 1.8e-40 DJ nuclease activity
JMCGKLLD_01017 2.2e-109 yoaK S Protein of unknown function (DUF1275)
JMCGKLLD_01018 7e-110 drgA C nitroreductase
JMCGKLLD_01019 3.6e-120 T Xre family transcriptional regulator
JMCGKLLD_01020 6.7e-143 T PhoQ Sensor
JMCGKLLD_01021 3.8e-90 S Psort location Cytoplasmic, score
JMCGKLLD_01022 3.9e-55 EL Toprim-like
JMCGKLLD_01023 4.7e-222 sip L Belongs to the 'phage' integrase family
JMCGKLLD_01024 6.8e-27 S MerR HTH family regulatory protein
JMCGKLLD_01025 2.9e-203
JMCGKLLD_01026 4.7e-97 D ftsk spoiiie
JMCGKLLD_01032 4.1e-48 K DNA-binding protein
JMCGKLLD_01033 4.8e-79
JMCGKLLD_01036 3.8e-28
JMCGKLLD_01037 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
JMCGKLLD_01038 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
JMCGKLLD_01039 1.9e-219 metE 2.1.1.14 E Methionine synthase
JMCGKLLD_01040 2.7e-239 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
JMCGKLLD_01041 1.3e-240 hisS 6.1.1.21 J histidyl-tRNA synthetase
JMCGKLLD_01043 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
JMCGKLLD_01044 4.2e-167 XK27_01785 S cog cog1284
JMCGKLLD_01045 5.5e-124 yaaA S Belongs to the UPF0246 family
JMCGKLLD_01046 2.4e-115 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JMCGKLLD_01047 2.4e-89 XK27_10930 K acetyltransferase
JMCGKLLD_01048 1.7e-13
JMCGKLLD_01049 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
JMCGKLLD_01050 2.5e-292 ccs S the current gene model (or a revised gene model) may contain a frame shift
JMCGKLLD_01051 3.2e-44 yrzB S Belongs to the UPF0473 family
JMCGKLLD_01052 1.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JMCGKLLD_01053 6.3e-44 yrzL S Belongs to the UPF0297 family
JMCGKLLD_01054 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
JMCGKLLD_01055 3.7e-235 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
JMCGKLLD_01057 9.7e-138 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JMCGKLLD_01058 5.9e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
JMCGKLLD_01059 9e-113 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
JMCGKLLD_01060 6.4e-224 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JMCGKLLD_01061 3.2e-235 rodA D Belongs to the SEDS family
JMCGKLLD_01062 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
JMCGKLLD_01063 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
JMCGKLLD_01064 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
JMCGKLLD_01065 1e-179 XK27_08075 M glycosyl transferase family 2
JMCGKLLD_01066 2.8e-97 S Carbohydrate-binding domain-containing protein Cthe_2159
JMCGKLLD_01067 1.7e-145 P molecular chaperone
JMCGKLLD_01068 7.6e-94 XK27_05505 S Psort location CytoplasmicMembrane, score
JMCGKLLD_01071 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
JMCGKLLD_01072 3.6e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JMCGKLLD_01073 1.1e-136 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
JMCGKLLD_01074 1.5e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JMCGKLLD_01075 2.3e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JMCGKLLD_01076 6.7e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
JMCGKLLD_01077 1.4e-104 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JMCGKLLD_01078 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JMCGKLLD_01080 2.6e-123 XK27_01040 S Protein of unknown function (DUF1129)
JMCGKLLD_01081 1e-168 corA P COG0598 Mg2 and Co2 transporters
JMCGKLLD_01082 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JMCGKLLD_01086 5.5e-33 blpT
JMCGKLLD_01087 1.8e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
JMCGKLLD_01088 1.3e-84 comEB 3.5.4.12 F ComE operon protein 2
JMCGKLLD_01089 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JMCGKLLD_01090 1.7e-61 yqhY S protein conserved in bacteria
JMCGKLLD_01091 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JMCGKLLD_01092 9.2e-178 scrR K Transcriptional regulator
JMCGKLLD_01093 5.1e-289 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
JMCGKLLD_01094 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
JMCGKLLD_01095 4.5e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
JMCGKLLD_01096 5.6e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
JMCGKLLD_01098 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
JMCGKLLD_01099 4.2e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JMCGKLLD_01100 1.9e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JMCGKLLD_01101 3.4e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
JMCGKLLD_01102 2.1e-202 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JMCGKLLD_01103 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JMCGKLLD_01106 1.9e-164 sitA P Belongs to the bacterial solute-binding protein 9 family
JMCGKLLD_01107 2.1e-133 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
JMCGKLLD_01108 6e-129 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
JMCGKLLD_01109 6.7e-73 S Psort location CytoplasmicMembrane, score
JMCGKLLD_01110 4.8e-64 S Domain of unknown function (DUF4430)
JMCGKLLD_01111 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JMCGKLLD_01112 1.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
JMCGKLLD_01113 9.4e-112 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
JMCGKLLD_01114 3.6e-172 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
JMCGKLLD_01115 2.2e-114 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
JMCGKLLD_01116 9.3e-92 dps P Belongs to the Dps family
JMCGKLLD_01117 5.2e-83 perR P Belongs to the Fur family
JMCGKLLD_01118 2.4e-27 yqgQ S protein conserved in bacteria
JMCGKLLD_01119 1.9e-178 glk 2.7.1.2 G Glucokinase
JMCGKLLD_01120 0.0 typA T GTP-binding protein TypA
JMCGKLLD_01122 1e-251 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JMCGKLLD_01123 1.9e-200 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JMCGKLLD_01124 1.2e-131 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
JMCGKLLD_01125 7.1e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
JMCGKLLD_01126 1.2e-233 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JMCGKLLD_01127 1e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JMCGKLLD_01128 7.7e-87 sepF D cell septum assembly
JMCGKLLD_01129 2.9e-30 yggT D integral membrane protein
JMCGKLLD_01130 1.5e-144 ylmH S conserved protein, contains S4-like domain
JMCGKLLD_01131 8.4e-138 divIVA D Cell division initiation protein
JMCGKLLD_01132 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JMCGKLLD_01134 2.4e-150 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
JMCGKLLD_01135 2e-106 pgm G Belongs to the phosphoglycerate mutase family
JMCGKLLD_01136 6.3e-108 G Belongs to the phosphoglycerate mutase family
JMCGKLLD_01137 8.1e-108 G Belongs to the phosphoglycerate mutase family
JMCGKLLD_01138 1e-196 S hmm pf01594
JMCGKLLD_01139 5.8e-285 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JMCGKLLD_01140 4.9e-39 S granule-associated protein
JMCGKLLD_01141 8e-288 S unusual protein kinase
JMCGKLLD_01142 1.3e-103 estA E Lysophospholipase L1 and related esterases
JMCGKLLD_01143 2.2e-159 rssA S Phospholipase, patatin family
JMCGKLLD_01144 8e-183 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
JMCGKLLD_01145 2.3e-251 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
JMCGKLLD_01146 1.5e-217 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JMCGKLLD_01147 4.5e-120 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JMCGKLLD_01148 2.8e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
JMCGKLLD_01149 0.0 S the current gene model (or a revised gene model) may contain a frame shift
JMCGKLLD_01150 1.4e-234 2.7.13.3 T protein histidine kinase activity
JMCGKLLD_01151 9.7e-212 hpk9 2.7.13.3 T protein histidine kinase activity
JMCGKLLD_01152 2.3e-184 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
JMCGKLLD_01153 6.4e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
JMCGKLLD_01154 0.0 lpdA 1.8.1.4 C Dehydrogenase
JMCGKLLD_01155 0.0 L helicase
JMCGKLLD_01156 3.6e-64 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
JMCGKLLD_01157 1.4e-10
JMCGKLLD_01158 8.1e-233 mntH P H( )-stimulated, divalent metal cation uptake system
JMCGKLLD_01159 1.1e-33 XK27_12190 S protein conserved in bacteria
JMCGKLLD_01161 1.1e-87 bioY S biotin synthase
JMCGKLLD_01162 7.5e-252 yegQ O Peptidase U32
JMCGKLLD_01163 2e-177 yegQ O Peptidase U32
JMCGKLLD_01165 4.2e-69 ytxH S General stress protein
JMCGKLLD_01166 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JMCGKLLD_01167 9.6e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JMCGKLLD_01168 8e-171 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JMCGKLLD_01169 2.2e-41 pspC KT PspC domain
JMCGKLLD_01170 0.0 yhgF K Transcriptional accessory protein
JMCGKLLD_01172 7.8e-155 XK27_03015 S permease
JMCGKLLD_01173 9.9e-149 ycgQ S TIGR03943 family
JMCGKLLD_01174 1.9e-287 sulP P Sulfate permease and related transporters (MFS superfamily)
JMCGKLLD_01175 1.4e-102
JMCGKLLD_01176 1.4e-118 estA E GDSL-like Lipase/Acylhydrolase
JMCGKLLD_01177 1.9e-51
JMCGKLLD_01179 6.7e-65 yqeB S Pyrimidine dimer DNA glycosylase
JMCGKLLD_01180 3.2e-60 S Protein of unknown function (DUF1722)
JMCGKLLD_01181 2.2e-19 S Bacterial lipoprotein
JMCGKLLD_01182 6.8e-11
JMCGKLLD_01183 5e-123 V CAAX protease self-immunity
JMCGKLLD_01184 2.7e-124 V CAAX protease self-immunity
JMCGKLLD_01185 1.5e-60
JMCGKLLD_01186 1.2e-118 S Domain of unknown function (DUF4300)
JMCGKLLD_01188 8.3e-37 yeeD O sulfur carrier activity
JMCGKLLD_01189 6.8e-187 yeeE S Sulphur transport
JMCGKLLD_01190 5.1e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JMCGKLLD_01191 2.6e-09 S NTF2 fold immunity protein
JMCGKLLD_01192 3.6e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
JMCGKLLD_01193 2e-08 XK27_10305 S Domain of unknown function (DUF4651)
JMCGKLLD_01194 3.7e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
JMCGKLLD_01195 5.7e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JMCGKLLD_01196 6.2e-101 S CAAX amino terminal protease family protein
JMCGKLLD_01198 2.5e-110 V CAAX protease self-immunity
JMCGKLLD_01199 8.8e-27 lanR K sequence-specific DNA binding
JMCGKLLD_01200 2.7e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JMCGKLLD_01201 3.2e-175 ytxK 2.1.1.72 L DNA methylase
JMCGKLLD_01202 2e-12 comGF U Putative Competence protein ComGF
JMCGKLLD_01203 4.5e-71 comGF U Competence protein ComGF
JMCGKLLD_01204 3.1e-15 NU Type II secretory pathway pseudopilin
JMCGKLLD_01205 8.4e-70 cglD NU Competence protein
JMCGKLLD_01206 2.2e-43 comGC U Required for transformation and DNA binding
JMCGKLLD_01207 1.1e-142 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JMCGKLLD_01208 1.1e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JMCGKLLD_01209 1e-68 S cog cog4699
JMCGKLLD_01210 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JMCGKLLD_01211 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JMCGKLLD_01212 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JMCGKLLD_01213 7.9e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JMCGKLLD_01214 2.6e-174 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JMCGKLLD_01215 1.4e-67 mgrA K Transcriptional regulator, MarR family
JMCGKLLD_01216 1.2e-65 ymdB S Macro domain protein
JMCGKLLD_01217 4.4e-86 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
JMCGKLLD_01218 5.6e-42 C Pyridoxamine 5'-phosphate oxidase
JMCGKLLD_01219 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
JMCGKLLD_01220 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
JMCGKLLD_01223 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
JMCGKLLD_01225 1e-20 L the current gene model (or a revised gene model) may contain a frame shift
JMCGKLLD_01226 4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
JMCGKLLD_01227 5.8e-137 yfeJ 6.3.5.2 F glutamine amidotransferase
JMCGKLLD_01228 2.3e-181 clcA_2 P Chloride transporter, ClC family
JMCGKLLD_01229 7.5e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JMCGKLLD_01230 2.9e-96 S Protein of unknown function (DUF1697)
JMCGKLLD_01231 8e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
JMCGKLLD_01232 1.5e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JMCGKLLD_01233 1.9e-253 V Glucan-binding protein C
JMCGKLLD_01234 1.8e-50 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
JMCGKLLD_01235 7.7e-224 XK27_05470 E Methionine synthase
JMCGKLLD_01236 1.1e-258 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JMCGKLLD_01237 6e-231 T PhoQ Sensor
JMCGKLLD_01238 1.5e-118 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JMCGKLLD_01239 4.2e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
JMCGKLLD_01240 9.2e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
JMCGKLLD_01241 3.7e-151 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JMCGKLLD_01242 1.5e-118 yjbM 2.7.6.5 S Gtp pyrophosphokinase
JMCGKLLD_01243 2.4e-101 yjbK S Adenylate cyclase
JMCGKLLD_01244 1.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JMCGKLLD_01245 2e-200 iscS 2.8.1.7 E Cysteine desulfurase
JMCGKLLD_01246 4.1e-59 XK27_04120 S Putative amino acid metabolism
JMCGKLLD_01247 2.1e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JMCGKLLD_01248 8.2e-128 puuD T peptidase C26
JMCGKLLD_01249 2.7e-115 radC E Belongs to the UPF0758 family
JMCGKLLD_01250 5.2e-167
JMCGKLLD_01251 1.2e-45 M Psort location CytoplasmicMembrane, score
JMCGKLLD_01252 4.3e-156 rfbJ M Glycosyl transferase family 2
JMCGKLLD_01253 0.0 rgpF M Rhamnan synthesis protein F
JMCGKLLD_01254 8.3e-185 rgpEc GT2 M Glycosyl transferase family 2
JMCGKLLD_01255 1.8e-223 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
JMCGKLLD_01256 2e-141 rgpC GM Transport permease protein
JMCGKLLD_01257 1.6e-174 rgpB GT2 M Glycosyltransferase, group 2 family protein
JMCGKLLD_01258 3.3e-214 rgpA GT4 M Domain of unknown function (DUF1972)
JMCGKLLD_01259 5.8e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
JMCGKLLD_01260 4.3e-267 S Glucosyl transferase GtrII
JMCGKLLD_01261 1.4e-107 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
JMCGKLLD_01262 3e-270 pelF GT4 M Domain of unknown function (DUF3492)
JMCGKLLD_01263 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
JMCGKLLD_01264 2.8e-144
JMCGKLLD_01265 2.7e-276 5.1.3.2 GM Psort location CytoplasmicMembrane, score
JMCGKLLD_01266 1.2e-211 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JMCGKLLD_01267 7.1e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
JMCGKLLD_01268 9.8e-305 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JMCGKLLD_01269 1.5e-86 ytsP 1.8.4.14 T GAF domain-containing protein
JMCGKLLD_01270 1.6e-160 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JMCGKLLD_01271 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
JMCGKLLD_01272 6.6e-08
JMCGKLLD_01273 5.6e-132 K cell adhesion
JMCGKLLD_01275 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
JMCGKLLD_01276 3.5e-214 XK27_05110 P Chloride transporter ClC family
JMCGKLLD_01277 1.3e-39 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
JMCGKLLD_01278 5.1e-279 clcA P Chloride transporter, ClC family
JMCGKLLD_01279 1e-75 fld C Flavodoxin
JMCGKLLD_01280 4.8e-18 XK27_08880
JMCGKLLD_01281 1.6e-126 XK27_08875 O Zinc-dependent metalloprotease
JMCGKLLD_01282 4.7e-148 estA CE1 S Esterase
JMCGKLLD_01283 9.3e-278 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JMCGKLLD_01284 5.3e-206 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
JMCGKLLD_01285 2.7e-171 S glycosyl transferase family 2
JMCGKLLD_01286 4e-85
JMCGKLLD_01287 4.4e-205 M glycosyl transferase group 1
JMCGKLLD_01288 1.1e-164 S Glycosyl transferase family 2
JMCGKLLD_01289 7.4e-160 licD M LICD family
JMCGKLLD_01290 4.3e-127 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
JMCGKLLD_01291 1.3e-257 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
JMCGKLLD_01292 6.1e-113 cpsD D COG0489 ATPases involved in chromosome partitioning
JMCGKLLD_01293 7.2e-116 cps4C M biosynthesis protein
JMCGKLLD_01294 7.3e-135 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
JMCGKLLD_01295 4e-241 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
JMCGKLLD_01296 9.1e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
JMCGKLLD_01297 1.1e-275 pepV 3.5.1.18 E Dipeptidase
JMCGKLLD_01298 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
JMCGKLLD_01299 1.9e-92 yybC
JMCGKLLD_01300 5.1e-53 XK27_03610 K Gnat family
JMCGKLLD_01301 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JMCGKLLD_01302 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
JMCGKLLD_01303 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JMCGKLLD_01304 1.6e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
JMCGKLLD_01305 9.3e-17 M LysM domain
JMCGKLLD_01306 8.6e-87 ebsA S Family of unknown function (DUF5322)
JMCGKLLD_01307 4.5e-230 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
JMCGKLLD_01308 4.2e-84 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
JMCGKLLD_01309 1.2e-38 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
JMCGKLLD_01310 5.9e-138 ET Belongs to the bacterial solute-binding protein 3 family
JMCGKLLD_01311 3.8e-140 ET ABC transporter
JMCGKLLD_01312 1.3e-84 mutT 3.6.1.55 F Nudix family
JMCGKLLD_01313 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
JMCGKLLD_01315 3.4e-169 S CAAX amino terminal protease family protein
JMCGKLLD_01316 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
JMCGKLLD_01317 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
JMCGKLLD_01318 1.7e-17 XK27_00735
JMCGKLLD_01319 1.5e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JMCGKLLD_01321 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JMCGKLLD_01322 5.7e-10 O ADP-ribosylglycohydrolase
JMCGKLLD_01323 6.7e-63 paaI Q protein possibly involved in aromatic compounds catabolism
JMCGKLLD_01324 2.7e-61 ycaO O OsmC-like protein
JMCGKLLD_01326 7.2e-153 EG Permeases of the drug metabolite transporter (DMT) superfamily
JMCGKLLD_01327 3.2e-07 N PFAM Uncharacterised protein family UPF0150
JMCGKLLD_01328 3.5e-112 serB 3.1.3.3 E phosphoserine phosphatase
JMCGKLLD_01329 1.1e-303 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JMCGKLLD_01330 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JMCGKLLD_01331 4.9e-99 3.1.3.18 S IA, variant 1
JMCGKLLD_01332 8.7e-67 lrgB M cytolysis
JMCGKLLD_01333 1.7e-47 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
JMCGKLLD_01334 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JMCGKLLD_01335 1e-202 V permease protein
JMCGKLLD_01336 2.6e-121 macB V ABC transporter, ATP-binding protein
JMCGKLLD_01337 3.4e-180 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JMCGKLLD_01338 6.2e-129 2.1.1.223 S Putative SAM-dependent methyltransferase
JMCGKLLD_01339 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
JMCGKLLD_01340 2.1e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
JMCGKLLD_01341 1.3e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
JMCGKLLD_01342 1.6e-222 pyrP F uracil Permease
JMCGKLLD_01343 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JMCGKLLD_01344 1.5e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JMCGKLLD_01345 4.4e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JMCGKLLD_01346 1.1e-167 fhuR K transcriptional regulator (lysR family)
JMCGKLLD_01348 5.1e-73 K Helix-turn-helix
JMCGKLLD_01350 9.3e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JMCGKLLD_01351 5.1e-308 S Glucan-binding protein C
JMCGKLLD_01352 2.7e-105 S CAAX amino terminal protease family protein
JMCGKLLD_01353 4.7e-168 K transcriptional regulator (lysR family)
JMCGKLLD_01354 9.6e-163 S reductase
JMCGKLLD_01355 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JMCGKLLD_01360 2.8e-191 phoH T phosphate starvation-inducible protein PhoH
JMCGKLLD_01361 6.2e-134 sip M LysM domain protein
JMCGKLLD_01362 3.7e-34 yozE S Belongs to the UPF0346 family
JMCGKLLD_01363 4.5e-160 cvfB S Protein conserved in bacteria
JMCGKLLD_01364 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
JMCGKLLD_01365 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
JMCGKLLD_01366 1.8e-215 sptS 2.7.13.3 T Histidine kinase
JMCGKLLD_01367 4.9e-117 T response regulator
JMCGKLLD_01368 8.2e-111 2.7.6.5 S Region found in RelA / SpoT proteins
JMCGKLLD_01369 1.8e-113 K Acetyltransferase (GNAT) family
JMCGKLLD_01370 7.1e-181 lmrA2 V abc transporter atp-binding protein
JMCGKLLD_01371 1.2e-33 S Immunity protein 41
JMCGKLLD_01372 0.0 pepO 3.4.24.71 O Peptidase family M13
JMCGKLLD_01373 1.5e-07 S Enterocin A Immunity
JMCGKLLD_01374 9.8e-194 mccF V LD-carboxypeptidase
JMCGKLLD_01375 1.2e-15 S integral membrane protein
JMCGKLLD_01376 1.1e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
JMCGKLLD_01377 3.1e-117 yhfC S Putative membrane peptidase family (DUF2324)
JMCGKLLD_01378 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
JMCGKLLD_01380 5.4e-241 S dextransucrase activity
JMCGKLLD_01381 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
JMCGKLLD_01382 5.6e-135 agrA KT response regulator
JMCGKLLD_01383 2.9e-230 2.7.13.3 T GHKL domain
JMCGKLLD_01385 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
JMCGKLLD_01386 1.3e-142 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
JMCGKLLD_01387 2.9e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
JMCGKLLD_01388 8.5e-190 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JMCGKLLD_01389 8.6e-218 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JMCGKLLD_01390 5.6e-127 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
JMCGKLLD_01391 7.9e-205 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
JMCGKLLD_01392 1.1e-134 yxkH G deacetylase
JMCGKLLD_01393 6.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
JMCGKLLD_01394 7e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
JMCGKLLD_01395 3.3e-150 rarD S Transporter
JMCGKLLD_01396 6.2e-18 T peptidase
JMCGKLLD_01397 3e-14 coiA 3.6.4.12 S Competence protein
JMCGKLLD_01398 2.2e-102 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JMCGKLLD_01399 2.4e-159 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JMCGKLLD_01400 1.6e-82 S Putative small multi-drug export protein
JMCGKLLD_01401 1.8e-75 ctsR K Belongs to the CtsR family
JMCGKLLD_01402 0.0 clpC O Belongs to the ClpA ClpB family
JMCGKLLD_01403 7.6e-233 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JMCGKLLD_01404 6e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JMCGKLLD_01405 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
JMCGKLLD_01406 5.1e-139 S SseB protein N-terminal domain
JMCGKLLD_01407 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
JMCGKLLD_01409 8.1e-257 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
JMCGKLLD_01410 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JMCGKLLD_01412 9.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JMCGKLLD_01413 2.7e-91 yacP S RNA-binding protein containing a PIN domain
JMCGKLLD_01414 4.1e-153 degV S DegV family
JMCGKLLD_01416 5.1e-22 K Transcriptional
JMCGKLLD_01417 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JMCGKLLD_01418 3.2e-14
JMCGKLLD_01419 3.8e-243 dcuS 2.7.13.3 T protein histidine kinase activity
JMCGKLLD_01420 1e-246 2.7.13.3 T protein histidine kinase activity
JMCGKLLD_01421 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JMCGKLLD_01422 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
JMCGKLLD_01423 1.4e-125 S Protein of unknown function (DUF554)
JMCGKLLD_01424 6.8e-133 ecsA_2 V abc transporter atp-binding protein
JMCGKLLD_01425 7.9e-251 XK27_00765
JMCGKLLD_01426 5.7e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JMCGKLLD_01427 4.2e-223 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JMCGKLLD_01428 3.1e-63 yhaI S Protein of unknown function (DUF805)
JMCGKLLD_01429 5e-69 yhaI J Protein of unknown function (DUF805)
JMCGKLLD_01432 3.7e-25
JMCGKLLD_01433 1.3e-93 adk 2.7.4.3 F topology modulation protein
JMCGKLLD_01434 2.7e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JMCGKLLD_01435 1.7e-78 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JMCGKLLD_01436 9.7e-36 XK27_09805 S MORN repeat protein
JMCGKLLD_01437 0.0 XK27_09800 I Acyltransferase
JMCGKLLD_01438 3e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
JMCGKLLD_01439 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
JMCGKLLD_01440 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JMCGKLLD_01441 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
JMCGKLLD_01442 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
JMCGKLLD_01443 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JMCGKLLD_01444 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JMCGKLLD_01445 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JMCGKLLD_01446 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JMCGKLLD_01447 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JMCGKLLD_01448 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
JMCGKLLD_01449 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JMCGKLLD_01450 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JMCGKLLD_01451 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JMCGKLLD_01452 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JMCGKLLD_01453 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JMCGKLLD_01454 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JMCGKLLD_01455 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JMCGKLLD_01456 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JMCGKLLD_01457 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JMCGKLLD_01458 1.9e-23 rpmD J ribosomal protein l30
JMCGKLLD_01459 5.7e-58 rplO J binds to the 23S rRNA
JMCGKLLD_01460 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
JMCGKLLD_01461 7.3e-118 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
JMCGKLLD_01462 2.1e-131 ecsA V AAA domain, putative AbiEii toxin, Type IV TA system
JMCGKLLD_01463 3.3e-104 K Transcriptional regulator
JMCGKLLD_01464 1.5e-36 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JMCGKLLD_01465 5.9e-55
JMCGKLLD_01466 8.7e-60
JMCGKLLD_01467 1.1e-49
JMCGKLLD_01468 1e-257 yheS_2 S ATPase components of ABC transporters with duplicated ATPase domains
JMCGKLLD_01469 2e-217 EGP Transmembrane secretion effector
JMCGKLLD_01470 4.3e-22
JMCGKLLD_01471 1.9e-253 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JMCGKLLD_01472 2e-97 mip S hydroperoxide reductase activity
JMCGKLLD_01473 1.7e-201 I acyl-CoA dehydrogenase
JMCGKLLD_01474 8.4e-152 ydiA P C4-dicarboxylate transporter malic acid transport
JMCGKLLD_01475 2.1e-247 msrR K Transcriptional regulator
JMCGKLLD_01476 8.8e-153 pheA 4.2.1.51 E Prephenate dehydratase
JMCGKLLD_01477 4.5e-80 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JMCGKLLD_01478 7.5e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
JMCGKLLD_01479 1.4e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
JMCGKLLD_01480 4.2e-53 yheA S Belongs to the UPF0342 family
JMCGKLLD_01481 4.3e-155 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
JMCGKLLD_01482 6.3e-18 S Protein of unknown function (DUF3021)
JMCGKLLD_01483 2.7e-124 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
JMCGKLLD_01484 3.9e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
JMCGKLLD_01485 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
JMCGKLLD_01486 9.1e-234 sufD O assembly protein SufD
JMCGKLLD_01487 1.3e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JMCGKLLD_01488 9.4e-74 nifU C SUF system FeS assembly protein, NifU family
JMCGKLLD_01489 2.9e-273 sufB O assembly protein SufB
JMCGKLLD_01490 2.7e-26
JMCGKLLD_01491 4.3e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JMCGKLLD_01492 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JMCGKLLD_01493 2e-71 adcR K transcriptional
JMCGKLLD_01494 2.4e-135 adcC P ABC transporter, ATP-binding protein
JMCGKLLD_01495 3.9e-129 adcB P ABC transporter (Permease
JMCGKLLD_01496 2.9e-160 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
JMCGKLLD_01497 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
JMCGKLLD_01498 4.6e-154 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
JMCGKLLD_01499 6e-143 S Macro domain protein
JMCGKLLD_01500 2.4e-50 trxA O Belongs to the thioredoxin family
JMCGKLLD_01501 7.2e-74 yccU S CoA-binding protein
JMCGKLLD_01502 2.7e-143 tatD L Hydrolase, tatd
JMCGKLLD_01503 8.2e-10 T Histidine kinase
JMCGKLLD_01504 7.3e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JMCGKLLD_01505 3.1e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
JMCGKLLD_01507 6.8e-164 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
JMCGKLLD_01508 7.8e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
JMCGKLLD_01509 1.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
JMCGKLLD_01510 1.4e-170 rmuC S RmuC domain protein
JMCGKLLD_01511 3.1e-178 cbf S 3'-5' exoribonuclease yhaM
JMCGKLLD_01512 4e-142 purR 2.4.2.7 F operon repressor
JMCGKLLD_01513 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JMCGKLLD_01514 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
JMCGKLLD_01515 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JMCGKLLD_01516 7.9e-188 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
JMCGKLLD_01517 7.1e-14
JMCGKLLD_01518 2e-146 yidA S hydrolases of the HAD superfamily
JMCGKLLD_01519 4.1e-207 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
JMCGKLLD_01520 1.3e-57 S Protein of unknown function (DUF454)
JMCGKLLD_01521 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
JMCGKLLD_01522 1e-235 vicK 2.7.13.3 T Histidine kinase
JMCGKLLD_01523 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JMCGKLLD_01524 2.7e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
JMCGKLLD_01525 3.8e-148 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
JMCGKLLD_01526 1.9e-116 gltJ P ABC transporter (Permease
JMCGKLLD_01527 2.9e-111 tcyB_2 P ABC transporter (permease)
JMCGKLLD_01528 6.5e-154 endA F DNA RNA non-specific endonuclease
JMCGKLLD_01529 5.5e-26 epuA S DNA-directed RNA polymerase subunit beta
JMCGKLLD_01530 7.7e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JMCGKLLD_01532 7.4e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JMCGKLLD_01533 3.2e-134 G Domain of unknown function (DUF4832)
JMCGKLLD_01534 2.7e-83 S membrane
JMCGKLLD_01535 5.7e-95 P VTC domain
JMCGKLLD_01536 5e-125 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JMCGKLLD_01538 2e-35 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JMCGKLLD_01539 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
JMCGKLLD_01540 5.3e-69 argR K Regulates arginine biosynthesis genes
JMCGKLLD_01541 1.1e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
JMCGKLLD_01542 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JMCGKLLD_01543 3e-78 S Protein of unknown function (DUF3021)
JMCGKLLD_01544 1.4e-69 K LytTr DNA-binding domain
JMCGKLLD_01546 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JMCGKLLD_01548 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
JMCGKLLD_01549 7.1e-106 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
JMCGKLLD_01550 2.1e-230 cinA 3.5.1.42 S Belongs to the CinA family
JMCGKLLD_01551 1e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JMCGKLLD_01552 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
JMCGKLLD_01553 3.6e-180 dapB 1.4.1.12, 1.4.1.16, 1.4.1.26 S Dihydrodipicolinate reductase, N-terminus
JMCGKLLD_01554 3.8e-11
JMCGKLLD_01555 8.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
JMCGKLLD_01556 1.5e-140 M LysM domain
JMCGKLLD_01557 8.4e-23
JMCGKLLD_01558 5.2e-175 S hydrolase
JMCGKLLD_01559 7.8e-117 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
JMCGKLLD_01560 2.7e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JMCGKLLD_01561 5.9e-142 XK27_00880 3.4.17.14, 3.5.1.28 M Glycosyl hydrolase, family 25
JMCGKLLD_01562 2e-26 P Hemerythrin HHE cation binding domain protein
JMCGKLLD_01563 1.7e-159 5.2.1.8 G hydrolase
JMCGKLLD_01564 1.4e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JMCGKLLD_01565 1.1e-214 MA20_36090 S Protein of unknown function (DUF2974)
JMCGKLLD_01566 4.6e-132 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JMCGKLLD_01568 1.9e-45 S Nucleotide pyrophosphohydrolase
JMCGKLLD_01569 7.9e-35 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
JMCGKLLD_01570 3e-87 S Fusaric acid resistance protein-like
JMCGKLLD_01571 2.5e-62 glnR K Transcriptional regulator
JMCGKLLD_01572 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
JMCGKLLD_01573 4.7e-114 pscB M CHAP domain protein
JMCGKLLD_01574 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JMCGKLLD_01575 1.5e-33 ykzG S Belongs to the UPF0356 family
JMCGKLLD_01576 1.6e-115 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
JMCGKLLD_01577 6.9e-72 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
JMCGKLLD_01578 2.8e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JMCGKLLD_01579 1.5e-113 azlC E AzlC protein
JMCGKLLD_01580 1.3e-46 azlD S branched-chain amino acid
JMCGKLLD_01581 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
JMCGKLLD_01582 1.5e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
JMCGKLLD_01583 5.9e-155 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JMCGKLLD_01584 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JMCGKLLD_01585 6.1e-94 cvpA S toxin biosynthetic process
JMCGKLLD_01586 8.3e-137 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
JMCGKLLD_01587 3.8e-221 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JMCGKLLD_01588 4.9e-93 5.4.2.11 G phosphoglycerate mutase family protein
JMCGKLLD_01589 1.8e-76 3.5.1.19 Q Isochorismatase family
JMCGKLLD_01590 1.2e-79 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
JMCGKLLD_01591 6.3e-108 XK27_09620 S FMN reductase (NADPH) activity
JMCGKLLD_01592 7.9e-230 XK27_09615 C reductase
JMCGKLLD_01593 2.1e-140 fnt P Formate nitrite transporter
JMCGKLLD_01594 2.1e-97 XK27_08585 S Psort location CytoplasmicMembrane, score
JMCGKLLD_01595 9.7e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
JMCGKLLD_01596 6.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
JMCGKLLD_01597 9.8e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
JMCGKLLD_01598 2.8e-96 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JMCGKLLD_01599 7.1e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
JMCGKLLD_01600 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
JMCGKLLD_01601 1.8e-141 S HAD hydrolase, family IA, variant
JMCGKLLD_01602 1.2e-160 rrmA 2.1.1.187 Q methyltransferase
JMCGKLLD_01606 3.5e-09 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
JMCGKLLD_01607 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
JMCGKLLD_01610 7.8e-277 thrC 4.2.3.1 E Threonine synthase
JMCGKLLD_01611 3.2e-226 norN V Mate efflux family protein
JMCGKLLD_01612 1.4e-57 asp S cog cog1302
JMCGKLLD_01613 6e-302 yloV S kinase related to dihydroxyacetone kinase
JMCGKLLD_01614 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
JMCGKLLD_01615 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
JMCGKLLD_01616 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
JMCGKLLD_01617 2.3e-60 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
JMCGKLLD_01618 1.3e-73 K transcriptional
JMCGKLLD_01619 4.8e-235 S COG1073 Hydrolases of the alpha beta superfamily
JMCGKLLD_01620 6e-152 cylA V abc transporter atp-binding protein
JMCGKLLD_01621 2.7e-125 cylB V ABC-2 type transporter
JMCGKLLD_01622 9e-75 K COG3279 Response regulator of the LytR AlgR family
JMCGKLLD_01623 5.2e-32 S Protein of unknown function (DUF3021)
JMCGKLLD_01624 8.1e-123 mta K Transcriptional
JMCGKLLD_01625 4.7e-120 yhcA V abc transporter atp-binding protein
JMCGKLLD_01626 3.6e-217 macB_2 V FtsX-like permease family
JMCGKLLD_01627 1.9e-272 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JMCGKLLD_01628 4.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
JMCGKLLD_01629 1.1e-77 yhaI S Protein of unknown function (DUF805)
JMCGKLLD_01630 2e-255 pepC 3.4.22.40 E aminopeptidase
JMCGKLLD_01631 2.1e-275 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JMCGKLLD_01634 5.8e-146 V Psort location CytoplasmicMembrane, score
JMCGKLLD_01636 9.2e-300 O MreB/Mbl protein
JMCGKLLD_01637 6.3e-112 liaI S membrane
JMCGKLLD_01638 6.8e-75 XK27_02470 K LytTr DNA-binding domain protein
JMCGKLLD_01639 0.0 KT response to antibiotic
JMCGKLLD_01640 3.4e-129 yebC M Membrane
JMCGKLLD_01641 1.2e-260 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
JMCGKLLD_01642 3.7e-179 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
JMCGKLLD_01644 2.9e-31 yozG K Transcriptional regulator
JMCGKLLD_01645 2e-208 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
JMCGKLLD_01646 5.5e-250 ydaM M Glycosyltransferases, probably involved in cell wall biogenesis
JMCGKLLD_01648 3.2e-136
JMCGKLLD_01649 1.1e-214 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
JMCGKLLD_01650 0.0 V ABC transporter (Permease
JMCGKLLD_01651 8.6e-125 V abc transporter atp-binding protein
JMCGKLLD_01652 1.8e-43 tetR K transcriptional regulator
JMCGKLLD_01653 1e-27 tetR K transcriptional regulator
JMCGKLLD_01654 2.7e-135 S Phenazine biosynthesis protein
JMCGKLLD_01655 6.9e-19
JMCGKLLD_01656 1.5e-29 K Helix-turn-helix domain
JMCGKLLD_01657 6e-85
JMCGKLLD_01658 8.5e-140 srtB 3.4.22.70 S sortase, SrtB family
JMCGKLLD_01659 4.3e-233 capA M Bacterial capsule synthesis protein
JMCGKLLD_01660 6.1e-39 gcvR T UPF0237 protein
JMCGKLLD_01661 2.3e-243 XK27_08635 S UPF0210 protein
JMCGKLLD_01662 7.3e-132 ais G Phosphoglycerate mutase
JMCGKLLD_01663 3.7e-140 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
JMCGKLLD_01664 7.2e-101 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
JMCGKLLD_01665 1.4e-184 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
JMCGKLLD_01666 8.2e-64 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JMCGKLLD_01667 7.5e-156 fasC T protein histidine kinase activity
JMCGKLLD_01668 7.2e-130 fasA KT Response regulator of the LytR AlgR family
JMCGKLLD_01669 5.8e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
JMCGKLLD_01670 1.3e-268 argH 4.3.2.1 E Argininosuccinate lyase
JMCGKLLD_01671 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
JMCGKLLD_01672 3.3e-147 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JMCGKLLD_01673 4.2e-152 jag S RNA-binding protein
JMCGKLLD_01674 9.3e-104 K Transcriptional regulator
JMCGKLLD_01675 2.2e-102 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
JMCGKLLD_01676 3.4e-14 rpmH J Ribosomal protein L34
JMCGKLLD_01677 2.8e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
JMCGKLLD_01678 9.8e-126 sitA P Belongs to the bacterial solute-binding protein 9 family
JMCGKLLD_01679 1.1e-118 sirR K iron dependent repressor
JMCGKLLD_01680 1.5e-134 htpX O Belongs to the peptidase M48B family
JMCGKLLD_01681 1.2e-92 lemA S LemA family
JMCGKLLD_01682 6.8e-176 spd F DNA RNA non-specific endonuclease
JMCGKLLD_01683 0.0 2.4.1.21 GT5 M Right handed beta helix region
JMCGKLLD_01684 6.9e-138 S double-stranded DNA endodeoxyribonuclease activity
JMCGKLLD_01685 4e-303 hsdM 2.1.1.72 V type I restriction-modification system
JMCGKLLD_01686 4.8e-109 S Protein conserved in bacteria
JMCGKLLD_01687 9.8e-253 ftsI 3.4.16.4 M penicillin-binding protein
JMCGKLLD_01688 9.1e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JMCGKLLD_01689 1.2e-220 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
JMCGKLLD_01692 9.6e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
JMCGKLLD_01693 1.8e-61 yutD J protein conserved in bacteria
JMCGKLLD_01694 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
JMCGKLLD_01695 2.7e-91 XK27_09885 V Glycopeptide antibiotics resistance protein
JMCGKLLD_01697 0.0 mdlA V abc transporter atp-binding protein
JMCGKLLD_01698 1e-31 yegS 2.7.1.107 I lipid kinase activity
JMCGKLLD_01699 1.6e-105 L Transposase
JMCGKLLD_01700 2.6e-40
JMCGKLLD_01701 0.0 ctpC 3.6.3.10, 3.6.3.4 P p-ATPase superfamily P-type ATPase copper transporter
JMCGKLLD_01702 1.2e-101 cadD P cadmium resistance
JMCGKLLD_01703 4.5e-55 cadC K Bacterial regulatory protein, arsR family
JMCGKLLD_01704 1.6e-16
JMCGKLLD_01705 1.4e-50 yiiE S protein homotetramerization
JMCGKLLD_01706 2.4e-11 K CsbD-like
JMCGKLLD_01708 6.7e-188 ysaA V VanZ like family
JMCGKLLD_01709 1.1e-39 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JMCGKLLD_01710 6.8e-220 L Belongs to the 'phage' integrase family
JMCGKLLD_01711 4.2e-18 S Domain of unknown function (DUF3173)
JMCGKLLD_01712 1.3e-139 yqeM Q Methyltransferase domain protein
JMCGKLLD_01713 7.7e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
JMCGKLLD_01714 2.4e-81 entB 3.5.1.19 Q Isochorismatase family
JMCGKLLD_01715 1.2e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
JMCGKLLD_01716 1.2e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JMCGKLLD_01717 7.7e-49 yhbY J RNA-binding protein
JMCGKLLD_01718 2.7e-213 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
JMCGKLLD_01719 4.7e-99 yqeG S hydrolase of the HAD superfamily
JMCGKLLD_01720 8.8e-154 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
JMCGKLLD_01721 3.9e-63
JMCGKLLD_01722 2e-215 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JMCGKLLD_01723 3.2e-57
JMCGKLLD_01724 1.7e-40 celC 2.7.1.196, 2.7.1.205 G Phosphotransferase system cellobiose-specific component IIA
JMCGKLLD_01725 1.3e-131 celR 2.7.1.194, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
JMCGKLLD_01726 5.4e-44 spiA K sequence-specific DNA binding
JMCGKLLD_01727 4.9e-136 blpT
JMCGKLLD_01730 2e-132 agrA KT LytTr DNA-binding domain
JMCGKLLD_01731 3.3e-218 blpH 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
JMCGKLLD_01733 2e-105 mesE M Transport protein ComB
JMCGKLLD_01734 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
JMCGKLLD_01740 1e-238 mdlB V abc transporter atp-binding protein
JMCGKLLD_01741 2.4e-127 arnC M group 2 family protein
JMCGKLLD_01742 1.8e-46 S Uncharacterized conserved protein (DUF2304)
JMCGKLLD_01743 2e-151 2.4.1.60 S Glycosyltransferase group 2 family protein
JMCGKLLD_01744 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
JMCGKLLD_01745 3.2e-223 M Psort location CytoplasmicMembrane, score
JMCGKLLD_01746 9.2e-239 GT4 M transferase activity, transferring glycosyl groups
JMCGKLLD_01747 4.6e-29 S Glucosyl transferase GtrII
JMCGKLLD_01748 3.8e-182 L the current gene model (or a revised gene model) may contain a
JMCGKLLD_01749 5.5e-32 WQ51_05710 S Mitochondrial biogenesis AIM24
JMCGKLLD_01750 9.2e-89 cah 4.2.1.1 P Reversible hydration of carbon dioxide
JMCGKLLD_01751 1.2e-50 S Protein of unknown function (DUF3397)
JMCGKLLD_01752 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JMCGKLLD_01753 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
JMCGKLLD_01754 0.0 amiA E ABC transporter, substrate-binding protein, family 5
JMCGKLLD_01755 1.8e-273 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JMCGKLLD_01756 6.7e-232 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
JMCGKLLD_01757 3.7e-157 hpk9 2.7.13.3 T protein histidine kinase activity
JMCGKLLD_01758 7.1e-210 hpk9 2.7.13.3 T protein histidine kinase activity
JMCGKLLD_01759 4.4e-287 norB P Major facilitator superfamily
JMCGKLLD_01760 1.9e-95 tetR K transcriptional regulator
JMCGKLLD_01761 5.6e-155 S Domain of unknown function (DUF4300)
JMCGKLLD_01762 1.5e-127 V CAAX protease self-immunity
JMCGKLLD_01763 6.3e-156 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JMCGKLLD_01764 3.4e-135 fecE 3.6.3.34 HP ABC transporter
JMCGKLLD_01765 8.5e-174 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
JMCGKLLD_01766 1.3e-130 ybbA S Putative esterase
JMCGKLLD_01767 2.9e-81 Q Methyltransferase domain
JMCGKLLD_01768 1.7e-73 K TetR family transcriptional regulator
JMCGKLLD_01769 6.4e-48
JMCGKLLD_01770 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JMCGKLLD_01772 1.3e-37
JMCGKLLD_01773 4.8e-07
JMCGKLLD_01775 6.1e-229 mutY L A G-specific adenine glycosylase
JMCGKLLD_01776 1.5e-42 XK27_05745
JMCGKLLD_01777 2.3e-99 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JMCGKLLD_01778 3.1e-136 XK27_08845 S abc transporter atp-binding protein
JMCGKLLD_01779 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
JMCGKLLD_01780 2.8e-177 XK27_08835 S ABC transporter substrate binding protein
JMCGKLLD_01781 3.8e-18 S Domain of unknown function (DUF4649)
JMCGKLLD_01782 1.5e-103 M lysozyme activity
JMCGKLLD_01783 1.3e-28 hol S Holin, phage phi LC3 family
JMCGKLLD_01784 3.4e-44
JMCGKLLD_01785 6.6e-11
JMCGKLLD_01786 1.1e-265
JMCGKLLD_01787 2.1e-124 S peptidoglycan catabolic process
JMCGKLLD_01788 8.1e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
JMCGKLLD_01789 4.6e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
JMCGKLLD_01790 3.6e-140 recO L Involved in DNA repair and RecF pathway recombination
JMCGKLLD_01791 1.1e-217 araT 2.6.1.1 E Aminotransferase
JMCGKLLD_01792 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JMCGKLLD_01793 3.1e-89 usp 3.5.1.28 CBM50 S CHAP domain
JMCGKLLD_01794 7.2e-84 mreD M rod shape-determining protein MreD
JMCGKLLD_01795 1.2e-106 mreC M Involved in formation and maintenance of cell shape
JMCGKLLD_01801 2.6e-10
JMCGKLLD_01808 5.4e-134 T Ser Thr phosphatase family protein
JMCGKLLD_01809 0.0 M Putative cell wall binding repeat
JMCGKLLD_01810 1.7e-227 thrE K Psort location CytoplasmicMembrane, score
JMCGKLLD_01811 9.4e-178 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
JMCGKLLD_01812 9.9e-95 dhaL 2.7.1.121 S Dihydroxyacetone kinase
JMCGKLLD_01813 3.1e-57 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
JMCGKLLD_01814 6.8e-128 S ABC-2 family transporter protein
JMCGKLLD_01815 3.7e-168 bcrA V abc transporter atp-binding protein
JMCGKLLD_01816 5.5e-226 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JMCGKLLD_01817 7.8e-152 E Alpha/beta hydrolase of unknown function (DUF915)
JMCGKLLD_01818 2e-74 ywnA K Transcriptional regulator
JMCGKLLD_01819 1.4e-150 1.13.11.2 S glyoxalase
JMCGKLLD_01820 4.3e-40 XK27_02070 S nitroreductase
JMCGKLLD_01821 3.8e-187 M Pilin isopeptide linkage domain protein
JMCGKLLD_01822 2e-64 K Transcriptional regulator C-terminal region
JMCGKLLD_01823 8.3e-101 V CAAX protease self-immunity
JMCGKLLD_01824 1.2e-163 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
JMCGKLLD_01825 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
JMCGKLLD_01834 1.9e-07
JMCGKLLD_01839 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JMCGKLLD_01840 1.1e-236 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
JMCGKLLD_01841 5.5e-36 XK27_02060 S Transglycosylase associated protein
JMCGKLLD_01842 3.9e-72 badR K Transcriptional regulator, marr family
JMCGKLLD_01843 3.2e-95 S reductase
JMCGKLLD_01844 1.6e-171 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
JMCGKLLD_01845 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
JMCGKLLD_01846 2.3e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
JMCGKLLD_01847 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
JMCGKLLD_01848 2.1e-32 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
JMCGKLLD_01849 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
JMCGKLLD_01850 1.9e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
JMCGKLLD_01851 3.3e-211 arcT 2.6.1.1 E Aminotransferase
JMCGKLLD_01852 3.3e-178 S Glucosyl transferase GtrII
JMCGKLLD_01853 2e-224 rgpA GT4 M Domain of unknown function (DUF1972)
JMCGKLLD_01854 1.7e-176 rgpB GT2 M Glycosyltransferase, group 2 family protein
JMCGKLLD_01855 6.8e-142 rgpC GM Transport permease protein
JMCGKLLD_01856 3.3e-225 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
JMCGKLLD_01857 1.3e-304 rgpF M Rhamnan synthesis protein F
JMCGKLLD_01859 1.3e-215 int L Belongs to the 'phage' integrase family
JMCGKLLD_01860 1.9e-18 S Domain of unknown function (DUF3173)
JMCGKLLD_01861 1.2e-156 L Replication initiation factor
JMCGKLLD_01862 5.5e-89 K TRANSCRIPTIONal
JMCGKLLD_01863 4.3e-81 S Short repeat of unknown function (DUF308)
JMCGKLLD_01864 1.8e-78 S membrane protein of uknown function UCP014873
JMCGKLLD_01865 4.9e-60 K sequence-specific DNA binding
JMCGKLLD_01866 2.1e-197 ltrA S Low temperature requirement protein
JMCGKLLD_01867 1.1e-65 L Transposase (IS116 IS110 IS902 family)
JMCGKLLD_01868 4.2e-141 L PFAM transposase IS116 IS110 IS902 family
JMCGKLLD_01869 1.3e-154 K sequence-specific DNA binding
JMCGKLLD_01870 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
JMCGKLLD_01871 6.4e-54 yhaI L Membrane
JMCGKLLD_01872 1.6e-38 S Domain of unknown function (DUF4173)
JMCGKLLD_01873 0.0
JMCGKLLD_01874 0.0 bcsA 2.4.1.12 GT2 M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
JMCGKLLD_01875 2.2e-148 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
JMCGKLLD_01876 2e-115
JMCGKLLD_01877 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
JMCGKLLD_01878 1.1e-44 K Helix-turn-helix domain
JMCGKLLD_01879 2e-45 S Phage derived protein Gp49-like (DUF891)
JMCGKLLD_01880 2.2e-73 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JMCGKLLD_01881 8.2e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
JMCGKLLD_01883 2.1e-238 6.3.2.2 H gamma-glutamylcysteine synthetase
JMCGKLLD_01884 4.4e-62 rplQ J ribosomal protein l17
JMCGKLLD_01885 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JMCGKLLD_01886 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JMCGKLLD_01887 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JMCGKLLD_01888 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
JMCGKLLD_01889 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JMCGKLLD_01890 1.4e-98 dnaK O Heat shock 70 kDa protein
JMCGKLLD_01891 2.1e-192 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
JMCGKLLD_01892 2e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
JMCGKLLD_01893 2.4e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
JMCGKLLD_01894 4.3e-80 hmpT S cog cog4720
JMCGKLLD_01895 7.2e-89 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
JMCGKLLD_01896 8.6e-254 V ABC-type multidrug transport system, ATPase and permease components
JMCGKLLD_01897 2.2e-75 C Arylsulfatase regulator (Fe-S oxidoreductase)
JMCGKLLD_01898 7.1e-118 gph 3.1.3.18 L hydrolase
JMCGKLLD_01899 5.3e-92 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JMCGKLLD_01900 2.3e-188
JMCGKLLD_01901 6.4e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JMCGKLLD_01902 2.5e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
JMCGKLLD_01903 1.3e-61 treB 2.7.1.201 G pts system
JMCGKLLD_01904 5.1e-125 treR K trehalose operon
JMCGKLLD_01905 1.9e-95 ywlG S Belongs to the UPF0340 family
JMCGKLLD_01909 1e-287 ahpF O alkyl hydroperoxide reductase
JMCGKLLD_01910 2.4e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
JMCGKLLD_01911 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
JMCGKLLD_01912 1.5e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JMCGKLLD_01913 8.2e-140 E Alpha beta hydrolase
JMCGKLLD_01916 5.3e-136 ald 1.4.1.1 C Belongs to the AlaDH PNT family
JMCGKLLD_01917 1.1e-131 XK27_12525 S AI-2E family transporter
JMCGKLLD_01918 2.2e-235 S the current gene model (or a revised gene model) may contain a frame shift
JMCGKLLD_01919 1e-75 K Transcriptional
JMCGKLLD_01920 3.6e-49 qacC P COG2076 Membrane transporters of cations and cationic drugs
JMCGKLLD_01921 6.9e-71 nudF 3.6.1.13, 3.6.1.22 L NAD+ diphosphatase activity
JMCGKLLD_01922 3.5e-280 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
JMCGKLLD_01923 2.6e-36 P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JMCGKLLD_01924 1.5e-36 L RePlication protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)