ORF_ID e_value Gene_name EC_number CAZy COGs Description
HGHAFENF_00001 7.7e-107 mltD CBM50 M NlpC P60 family protein
HGHAFENF_00002 8.3e-195 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HGHAFENF_00003 3.7e-28
HGHAFENF_00004 1.7e-187 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HGHAFENF_00005 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HGHAFENF_00006 3.1e-33 ykzG S Belongs to the UPF0356 family
HGHAFENF_00007 1.6e-85
HGHAFENF_00008 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HGHAFENF_00009 1.6e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HGHAFENF_00010 4.5e-180 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HGHAFENF_00011 1.8e-208 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HGHAFENF_00012 2.6e-266 lpdA 1.8.1.4 C Dehydrogenase
HGHAFENF_00013 1.4e-162 1.1.1.27 C L-malate dehydrogenase activity
HGHAFENF_00014 3.6e-45 yktA S Belongs to the UPF0223 family
HGHAFENF_00015 7e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HGHAFENF_00016 0.0 typA T GTP-binding protein TypA
HGHAFENF_00017 6e-120 ica2 GT2 M Glycosyl transferase family group 2
HGHAFENF_00018 1.3e-260
HGHAFENF_00019 1.6e-205 ftsW D Belongs to the SEDS family
HGHAFENF_00020 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HGHAFENF_00021 1.5e-49 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HGHAFENF_00022 1.7e-102 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HGHAFENF_00023 2.1e-85 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HGHAFENF_00024 9.6e-197 ylbL T Belongs to the peptidase S16 family
HGHAFENF_00025 1.2e-121 comEA L Competence protein ComEA
HGHAFENF_00026 6.4e-79 comEB 3.5.4.12 F ComE operon protein 2
HGHAFENF_00027 0.0 comEC S Competence protein ComEC
HGHAFENF_00028 4.1e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
HGHAFENF_00029 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
HGHAFENF_00030 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HGHAFENF_00031 6.3e-192 mdtG EGP Major Facilitator Superfamily
HGHAFENF_00032 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HGHAFENF_00033 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HGHAFENF_00034 1.1e-159 S Tetratricopeptide repeat
HGHAFENF_00035 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HGHAFENF_00036 4.1e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HGHAFENF_00037 3.3e-236 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HGHAFENF_00038 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
HGHAFENF_00039 2.2e-49 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HGHAFENF_00040 9.9e-73 S Iron-sulphur cluster biosynthesis
HGHAFENF_00041 4.3e-22
HGHAFENF_00042 9.2e-270 glnPH2 P ABC transporter permease
HGHAFENF_00043 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HGHAFENF_00044 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HGHAFENF_00045 2.9e-126 epsB M biosynthesis protein
HGHAFENF_00046 7.3e-124 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HGHAFENF_00047 3.5e-146 ywqE 3.1.3.48 GM PHP domain protein
HGHAFENF_00048 9.6e-180 cps4D 5.1.3.2 M RmlD substrate binding domain
HGHAFENF_00049 1.8e-127 tuaA M Bacterial sugar transferase
HGHAFENF_00050 1.2e-202 cps4F 2.4.1.21, 2.4.1.306 GT4,GT5 M Glycosyl transferases group 1
HGHAFENF_00051 1.1e-184 cps4G M Glycosyltransferase Family 4
HGHAFENF_00052 5.6e-231
HGHAFENF_00053 4.3e-175 cps4I M Glycosyltransferase like family 2
HGHAFENF_00054 1.4e-262 cps4J S Polysaccharide biosynthesis protein
HGHAFENF_00055 5.4e-253 cpdA S Calcineurin-like phosphoesterase
HGHAFENF_00056 6.7e-292 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
HGHAFENF_00057 5.1e-170 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HGHAFENF_00058 1.5e-135 fruR K DeoR C terminal sensor domain
HGHAFENF_00059 2.4e-245 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HGHAFENF_00060 3.2e-46
HGHAFENF_00061 2.8e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HGHAFENF_00062 5.6e-141 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HGHAFENF_00063 2e-50 yrvD S Lipopolysaccharide assembly protein A domain
HGHAFENF_00064 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HGHAFENF_00065 2.9e-93 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HGHAFENF_00066 1.5e-103 K Helix-turn-helix domain
HGHAFENF_00067 7.2e-212 EGP Major facilitator Superfamily
HGHAFENF_00068 8.5e-57 ybjQ S Belongs to the UPF0145 family
HGHAFENF_00069 2.1e-140 Q Methyltransferase
HGHAFENF_00070 1.6e-31
HGHAFENF_00073 4e-50 L Belongs to the 'phage' integrase family
HGHAFENF_00075 4.9e-43 L HTH-like domain
HGHAFENF_00077 2.7e-26 S Short C-terminal domain
HGHAFENF_00078 1.9e-17 S Short C-terminal domain
HGHAFENF_00081 3.4e-177 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
HGHAFENF_00082 3.5e-67
HGHAFENF_00083 1.1e-76
HGHAFENF_00084 1.3e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HGHAFENF_00085 3.2e-86
HGHAFENF_00086 5.6e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HGHAFENF_00087 2.9e-36 ynzC S UPF0291 protein
HGHAFENF_00088 4.3e-33 yneF S Uncharacterised protein family (UPF0154)
HGHAFENF_00089 1.2e-117 plsC 2.3.1.51 I Acyltransferase
HGHAFENF_00090 4.2e-133 yabB 2.1.1.223 L Methyltransferase small domain
HGHAFENF_00091 2e-49 yazA L GIY-YIG catalytic domain protein
HGHAFENF_00092 2.3e-187 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGHAFENF_00093 4.7e-134 S Haloacid dehalogenase-like hydrolase
HGHAFENF_00094 6.5e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
HGHAFENF_00095 3.9e-151 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HGHAFENF_00096 2.2e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HGHAFENF_00097 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HGHAFENF_00098 1.8e-147 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HGHAFENF_00099 8.4e-137 cdsA 2.7.7.41 I Belongs to the CDS family
HGHAFENF_00100 9.5e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HGHAFENF_00101 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HGHAFENF_00102 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HGHAFENF_00103 4.2e-83 rimP J Required for maturation of 30S ribosomal subunits
HGHAFENF_00104 3.3e-217 nusA K Participates in both transcription termination and antitermination
HGHAFENF_00105 9.5e-49 ylxR K Protein of unknown function (DUF448)
HGHAFENF_00106 1.1e-47 ylxQ J ribosomal protein
HGHAFENF_00107 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HGHAFENF_00108 4.6e-50 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HGHAFENF_00109 6.7e-265 ydiN 5.4.99.5 G Major Facilitator
HGHAFENF_00110 1e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HGHAFENF_00111 1.9e-92
HGHAFENF_00112 5.8e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HGHAFENF_00113 1.9e-195 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HGHAFENF_00114 2.4e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HGHAFENF_00115 9.4e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HGHAFENF_00116 1.2e-188 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HGHAFENF_00117 7.3e-132 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
HGHAFENF_00118 2.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HGHAFENF_00119 1.5e-80 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HGHAFENF_00120 0.0 dnaK O Heat shock 70 kDa protein
HGHAFENF_00121 7.8e-184 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HGHAFENF_00122 4.4e-198 pbpX2 V Beta-lactamase
HGHAFENF_00123 8.8e-19 dltX S D-Ala-teichoic acid biosynthesis protein
HGHAFENF_00124 7e-297 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGHAFENF_00125 8.7e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
HGHAFENF_00126 2.4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGHAFENF_00127 6.1e-246 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HGHAFENF_00128 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HGHAFENF_00129 1.4e-49
HGHAFENF_00130 1.4e-49
HGHAFENF_00131 3.6e-114 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HGHAFENF_00132 4.5e-177 prmA J Ribosomal protein L11 methyltransferase
HGHAFENF_00133 1.1e-133 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HGHAFENF_00134 9.6e-58
HGHAFENF_00135 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HGHAFENF_00136 8.5e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HGHAFENF_00137 7.9e-114 3.1.3.18 J HAD-hyrolase-like
HGHAFENF_00138 1.1e-163 yniA G Fructosamine kinase
HGHAFENF_00139 4.3e-155 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HGHAFENF_00140 2.2e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
HGHAFENF_00141 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HGHAFENF_00142 1.6e-99 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HGHAFENF_00143 1.7e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HGHAFENF_00144 2.9e-223 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HGHAFENF_00145 1.9e-169 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HGHAFENF_00146 1.7e-128 C Enoyl-(Acyl carrier protein) reductase
HGHAFENF_00147 2.1e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HGHAFENF_00148 9.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HGHAFENF_00149 2.6e-71 yqeY S YqeY-like protein
HGHAFENF_00150 5.8e-180 phoH T phosphate starvation-inducible protein PhoH
HGHAFENF_00151 6.6e-84 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HGHAFENF_00152 4.5e-73 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HGHAFENF_00153 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HGHAFENF_00154 3.1e-147 recO L Involved in DNA repair and RecF pathway recombination
HGHAFENF_00155 6.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HGHAFENF_00156 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HGHAFENF_00157 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HGHAFENF_00158 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HGHAFENF_00159 3.6e-64 K helix_turn_helix gluconate operon transcriptional repressor
HGHAFENF_00160 4.8e-165 ytrB V ABC transporter, ATP-binding protein
HGHAFENF_00161 1.1e-200
HGHAFENF_00162 5.1e-198
HGHAFENF_00163 9.8e-127 S ABC-2 family transporter protein
HGHAFENF_00164 3.9e-162 V ABC transporter, ATP-binding protein
HGHAFENF_00165 2.6e-12 yjdF S Protein of unknown function (DUF2992)
HGHAFENF_00166 1e-114 S Psort location CytoplasmicMembrane, score
HGHAFENF_00167 6.2e-73 K MarR family
HGHAFENF_00168 6e-82 K Acetyltransferase (GNAT) domain
HGHAFENF_00170 2.6e-158 yvfR V ABC transporter
HGHAFENF_00171 3.1e-136 yvfS V ABC-2 type transporter
HGHAFENF_00172 8.2e-207 desK 2.7.13.3 T Histidine kinase
HGHAFENF_00173 1.2e-103 desR K helix_turn_helix, Lux Regulon
HGHAFENF_00174 2.3e-270 nox C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HGHAFENF_00175 2.8e-14 S Alpha beta hydrolase
HGHAFENF_00176 1.9e-172 C nadph quinone reductase
HGHAFENF_00177 1.9e-161 K Transcriptional regulator
HGHAFENF_00178 9.8e-79 S Uncharacterized protein conserved in bacteria (DUF2255)
HGHAFENF_00179 3.1e-113 GM NmrA-like family
HGHAFENF_00180 1e-159 S Alpha beta hydrolase
HGHAFENF_00181 1.2e-129 K Helix-turn-helix domain, rpiR family
HGHAFENF_00182 1.5e-80 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
HGHAFENF_00183 1.3e-111 ppaX_1 3.1.3.18, 3.6.1.1 S haloacid dehalogenase-like hydrolase
HGHAFENF_00184 8e-28 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGHAFENF_00185 3.4e-72 S Alpha/beta hydrolase of unknown function (DUF915)
HGHAFENF_00186 9.4e-15 K Bacterial regulatory proteins, tetR family
HGHAFENF_00187 6.2e-214 S membrane
HGHAFENF_00188 7.8e-81 K Bacterial regulatory proteins, tetR family
HGHAFENF_00189 1.3e-179 CP_1020 S Zinc finger, swim domain protein
HGHAFENF_00190 2.8e-131 CP_1020 S Zinc finger, swim domain protein
HGHAFENF_00191 1.2e-112 GM epimerase
HGHAFENF_00192 1.4e-68 S Protein of unknown function (DUF1722)
HGHAFENF_00193 9.1e-71 yneH 1.20.4.1 P ArsC family
HGHAFENF_00194 1.7e-108 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
HGHAFENF_00195 8e-137 K DeoR C terminal sensor domain
HGHAFENF_00196 0.0 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HGHAFENF_00197 2.2e-175 tanA S alpha beta
HGHAFENF_00198 7e-209 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HGHAFENF_00199 4.3e-77 K Transcriptional regulator
HGHAFENF_00200 8.5e-241 EGP Major facilitator Superfamily
HGHAFENF_00201 8.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HGHAFENF_00202 0.0 3.6.3.6 P Cation transporter/ATPase, N-terminus
HGHAFENF_00203 6.2e-182 C Zinc-binding dehydrogenase
HGHAFENF_00204 5.7e-216 I transferase activity, transferring acyl groups other than amino-acyl groups
HGHAFENF_00205 3e-204
HGHAFENF_00206 3.6e-91 yetL K helix_turn_helix multiple antibiotic resistance protein
HGHAFENF_00207 1.9e-62 P Rhodanese Homology Domain
HGHAFENF_00208 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HGHAFENF_00209 3.1e-84 K helix_turn_helix multiple antibiotic resistance protein
HGHAFENF_00210 1.8e-165 drrA V ABC transporter
HGHAFENF_00211 5.4e-120 drrB U ABC-2 type transporter
HGHAFENF_00212 1.1e-220 M O-Antigen ligase
HGHAFENF_00213 1.6e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
HGHAFENF_00214 8.5e-198 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HGHAFENF_00215 3.1e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HGHAFENF_00216 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HGHAFENF_00218 5.6e-29 S Protein of unknown function (DUF2929)
HGHAFENF_00219 0.0 dnaE 2.7.7.7 L DNA polymerase
HGHAFENF_00220 1.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HGHAFENF_00221 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HGHAFENF_00222 1.5e-74 yeaL S Protein of unknown function (DUF441)
HGHAFENF_00223 2.9e-170 cvfB S S1 domain
HGHAFENF_00224 1.1e-164 xerD D recombinase XerD
HGHAFENF_00225 4.8e-69 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGHAFENF_00226 5.7e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HGHAFENF_00227 7.9e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HGHAFENF_00228 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HGHAFENF_00229 1.1e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HGHAFENF_00230 9.9e-194 ypbB 5.1.3.1 S Helix-turn-helix domain
HGHAFENF_00231 2e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HGHAFENF_00232 2e-19 M Lysin motif
HGHAFENF_00233 3.8e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HGHAFENF_00234 1.8e-213 rpsA 1.17.7.4 J Ribosomal protein S1
HGHAFENF_00235 2.7e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HGHAFENF_00236 1.1e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HGHAFENF_00237 4.7e-206 S Tetratricopeptide repeat protein
HGHAFENF_00238 9.7e-149 3.1.3.102, 3.1.3.104 S hydrolase
HGHAFENF_00239 5.4e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HGHAFENF_00240 2.1e-227 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HGHAFENF_00241 9.6e-85
HGHAFENF_00242 0.0 yfmR S ABC transporter, ATP-binding protein
HGHAFENF_00243 1e-189 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HGHAFENF_00244 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HGHAFENF_00245 5.1e-148 DegV S EDD domain protein, DegV family
HGHAFENF_00246 2.1e-150 ypmR E GDSL-like Lipase/Acylhydrolase
HGHAFENF_00247 3.1e-113 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HGHAFENF_00248 3.4e-35 yozE S Belongs to the UPF0346 family
HGHAFENF_00249 2.1e-261 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HGHAFENF_00250 3.3e-251 emrY EGP Major facilitator Superfamily
HGHAFENF_00251 7.4e-197 XK27_00915 C Luciferase-like monooxygenase
HGHAFENF_00252 1.9e-124 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HGHAFENF_00253 2.3e-173 L restriction endonuclease
HGHAFENF_00254 2.3e-170 cpsY K Transcriptional regulator, LysR family
HGHAFENF_00255 1.4e-228 XK27_05470 E Methionine synthase
HGHAFENF_00256 1.8e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HGHAFENF_00257 9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HGHAFENF_00258 6.8e-139 dprA LU DNA protecting protein DprA
HGHAFENF_00259 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HGHAFENF_00260 1.2e-249 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HGHAFENF_00261 1.5e-177 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HGHAFENF_00262 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HGHAFENF_00263 2.3e-257 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HGHAFENF_00264 1.1e-169 lacX 5.1.3.3 G Aldose 1-epimerase
HGHAFENF_00265 5.2e-105 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HGHAFENF_00266 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HGHAFENF_00267 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HGHAFENF_00268 1.2e-177 K Transcriptional regulator
HGHAFENF_00269 1.7e-168 ppaC 3.6.1.1 C inorganic pyrophosphatase
HGHAFENF_00270 4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HGHAFENF_00271 1e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HGHAFENF_00272 4.2e-32 S YozE SAM-like fold
HGHAFENF_00273 2.1e-157 xerD L Phage integrase, N-terminal SAM-like domain
HGHAFENF_00274 1.5e-275 GT89 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HGHAFENF_00275 2.5e-242 M Glycosyl transferase family group 2
HGHAFENF_00276 9e-50
HGHAFENF_00277 4.1e-240 gshR1 1.8.1.7 C Glutathione reductase
HGHAFENF_00278 1.8e-72 mgrA K helix_turn_helix multiple antibiotic resistance protein
HGHAFENF_00279 8.5e-93 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HGHAFENF_00280 0.0 tarL 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HGHAFENF_00281 8.6e-196 tarK 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HGHAFENF_00282 7.7e-191 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HGHAFENF_00283 3.7e-128 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HGHAFENF_00284 2.6e-226
HGHAFENF_00285 1.8e-279 lldP C L-lactate permease
HGHAFENF_00286 4.1e-59
HGHAFENF_00287 3.5e-123
HGHAFENF_00288 5.4e-245 cycA E Amino acid permease
HGHAFENF_00289 2.5e-134 XK27_00890 S Domain of unknown function (DUF368)
HGHAFENF_00290 1.5e-128 yejC S Protein of unknown function (DUF1003)
HGHAFENF_00291 6.2e-51 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
HGHAFENF_00292 4.6e-12
HGHAFENF_00293 1.6e-211 pmrB EGP Major facilitator Superfamily
HGHAFENF_00294 1.6e-148 2.7.7.12 C Domain of unknown function (DUF4931)
HGHAFENF_00295 1.4e-49
HGHAFENF_00296 4.3e-10
HGHAFENF_00297 3.4e-132 S Protein of unknown function (DUF975)
HGHAFENF_00298 8.3e-78 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
HGHAFENF_00299 7e-161 degV S EDD domain protein, DegV family
HGHAFENF_00300 1.9e-66 K Transcriptional regulator
HGHAFENF_00301 0.0 FbpA K Fibronectin-binding protein
HGHAFENF_00302 1.5e-57 V ABC transporter, ATP-binding protein
HGHAFENF_00303 2.2e-90 3.6.1.55 F NUDIX domain
HGHAFENF_00304 3.6e-134 S Uncharacterized protein conserved in bacteria (DUF2087)
HGHAFENF_00305 3.5e-69 S LuxR family transcriptional regulator
HGHAFENF_00306 4.6e-128 cat 2.3.1.28 V Chloramphenicol acetyltransferase
HGHAFENF_00308 5.8e-70 frataxin S Domain of unknown function (DU1801)
HGHAFENF_00309 5.5e-112 pgm5 G Phosphoglycerate mutase family
HGHAFENF_00310 8.8e-288 S Bacterial membrane protein, YfhO
HGHAFENF_00311 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HGHAFENF_00312 8.1e-207 carA 6.3.5.5 F Belongs to the CarA family
HGHAFENF_00313 1.3e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HGHAFENF_00314 1e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HGHAFENF_00315 4.4e-74 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HGHAFENF_00316 2.1e-294 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HGHAFENF_00317 2.2e-61 esbA S Family of unknown function (DUF5322)
HGHAFENF_00318 2.2e-66 rnhA 3.1.26.4 L Ribonuclease HI
HGHAFENF_00319 9.5e-211 yurR 1.4.5.1 E FAD dependent oxidoreductase
HGHAFENF_00320 1.5e-146 S hydrolase activity, acting on ester bonds
HGHAFENF_00321 2.1e-194
HGHAFENF_00322 3.3e-121 3.6.3.35 P ATPases associated with a variety of cellular activities
HGHAFENF_00323 7.3e-122
HGHAFENF_00324 1.7e-73 XK27_05710 K Acetyltransferase (GNAT) domain
HGHAFENF_00325 1.6e-182 mccF 3.4.17.13 V LD-carboxypeptidase
HGHAFENF_00326 4.5e-239 M hydrolase, family 25
HGHAFENF_00327 1.2e-46 K Acetyltransferase (GNAT) domain
HGHAFENF_00328 1.2e-207 mccF V LD-carboxypeptidase
HGHAFENF_00329 1.9e-200 M Glycosyltransferase, group 2 family protein
HGHAFENF_00330 4.4e-73 S SnoaL-like domain
HGHAFENF_00331 8e-145 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HGHAFENF_00332 1.4e-93 P Major Facilitator Superfamily
HGHAFENF_00333 3.5e-64
HGHAFENF_00334 1.6e-75 yugI 5.3.1.9 J general stress protein
HGHAFENF_00335 5.5e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HGHAFENF_00336 3e-119 dedA S SNARE-like domain protein
HGHAFENF_00337 4.6e-117 S Protein of unknown function (DUF1461)
HGHAFENF_00338 1.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HGHAFENF_00339 1.5e-80 yutD S Protein of unknown function (DUF1027)
HGHAFENF_00340 8.7e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HGHAFENF_00341 4.4e-117 S Calcineurin-like phosphoesterase
HGHAFENF_00342 5.6e-253 cycA E Amino acid permease
HGHAFENF_00343 1.6e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HGHAFENF_00344 3.6e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
HGHAFENF_00346 4.5e-88 S Prokaryotic N-terminal methylation motif
HGHAFENF_00347 2.1e-18
HGHAFENF_00348 3.2e-83 gspG NU general secretion pathway protein
HGHAFENF_00349 5.5e-43 comGC U competence protein ComGC
HGHAFENF_00350 1.9e-189 comGB NU type II secretion system
HGHAFENF_00351 2.8e-174 comGA NU Type II IV secretion system protein
HGHAFENF_00352 4.8e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGHAFENF_00353 8.3e-131 yebC K Transcriptional regulatory protein
HGHAFENF_00354 1.6e-49 S DsrE/DsrF-like family
HGHAFENF_00355 2.3e-164 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HGHAFENF_00356 1.9e-181 ccpA K catabolite control protein A
HGHAFENF_00357 1.7e-215 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HGHAFENF_00358 1.1e-80 K helix_turn_helix, mercury resistance
HGHAFENF_00359 2.8e-56
HGHAFENF_00360 1.9e-23 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HGHAFENF_00361 2.6e-158 ykuT M mechanosensitive ion channel
HGHAFENF_00362 1.1e-225 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HGHAFENF_00363 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HGHAFENF_00364 6.5e-87 ykuL S (CBS) domain
HGHAFENF_00365 1.2e-94 S Phosphoesterase
HGHAFENF_00366 1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HGHAFENF_00367 4.1e-150 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HGHAFENF_00368 7.6e-126 yslB S Protein of unknown function (DUF2507)
HGHAFENF_00369 3.3e-52 trxA O Belongs to the thioredoxin family
HGHAFENF_00370 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HGHAFENF_00371 2.7e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HGHAFENF_00372 1.6e-48 yrzB S Belongs to the UPF0473 family
HGHAFENF_00373 7.3e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HGHAFENF_00374 2.4e-43 yrzL S Belongs to the UPF0297 family
HGHAFENF_00375 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HGHAFENF_00376 7.1e-245 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HGHAFENF_00377 7e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HGHAFENF_00378 5.3e-217 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HGHAFENF_00379 6.3e-29 yajC U Preprotein translocase
HGHAFENF_00380 1.3e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HGHAFENF_00381 6.3e-201 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HGHAFENF_00382 2.1e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HGHAFENF_00383 4.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HGHAFENF_00384 2.7e-91
HGHAFENF_00385 0.0 S Bacterial membrane protein YfhO
HGHAFENF_00386 1.3e-72
HGHAFENF_00387 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HGHAFENF_00388 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HGHAFENF_00389 2.7e-154 ymdB S YmdB-like protein
HGHAFENF_00390 2.1e-216 rny S Endoribonuclease that initiates mRNA decay
HGHAFENF_00391 5e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HGHAFENF_00392 2.7e-230 cinA 3.5.1.42 S Belongs to the CinA family
HGHAFENF_00393 3.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HGHAFENF_00394 5.7e-110 ymfM S Helix-turn-helix domain
HGHAFENF_00395 2.9e-251 ymfH S Peptidase M16
HGHAFENF_00396 1.9e-231 ymfF S Peptidase M16 inactive domain protein
HGHAFENF_00397 1e-254 lysC 2.7.2.4 E Belongs to the aspartokinase family
HGHAFENF_00398 1.5e-155 aatB ET ABC transporter substrate-binding protein
HGHAFENF_00399 2.5e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HGHAFENF_00400 4.6e-109 glnP P ABC transporter permease
HGHAFENF_00401 1.2e-146 minD D Belongs to the ParA family
HGHAFENF_00402 1.4e-116 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HGHAFENF_00403 1.2e-88 mreD M rod shape-determining protein MreD
HGHAFENF_00404 2.6e-144 mreC M Involved in formation and maintenance of cell shape
HGHAFENF_00405 2.8e-161 mreB D cell shape determining protein MreB
HGHAFENF_00406 1.3e-116 radC L DNA repair protein
HGHAFENF_00407 1.4e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HGHAFENF_00408 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HGHAFENF_00409 3e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HGHAFENF_00410 2e-233 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HGHAFENF_00411 1.9e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HGHAFENF_00412 1.7e-218 iscS2 2.8.1.7 E Aminotransferase class V
HGHAFENF_00413 0.0 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HGHAFENF_00414 5e-81 ytsP 1.8.4.14 T GAF domain-containing protein
HGHAFENF_00415 3.1e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HGHAFENF_00416 5.2e-113 yktB S Belongs to the UPF0637 family
HGHAFENF_00417 2.5e-80 yueI S Protein of unknown function (DUF1694)
HGHAFENF_00418 7e-110 S Protein of unknown function (DUF1648)
HGHAFENF_00419 8.6e-44 czrA K Helix-turn-helix domain
HGHAFENF_00420 6.2e-230 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HGHAFENF_00421 9.2e-42 2.7.1.191 G PTS system fructose IIA component
HGHAFENF_00422 2.7e-104 G PTS system mannose fructose sorbose family IID component
HGHAFENF_00423 3.6e-103 G PTS system sorbose-specific iic component
HGHAFENF_00424 6e-66 2.7.1.191 G PTS system sorbose subfamily IIB component
HGHAFENF_00425 5.9e-95 cytR 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
HGHAFENF_00426 0.0 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HGHAFENF_00427 8e-238 rarA L recombination factor protein RarA
HGHAFENF_00428 1.5e-38
HGHAFENF_00429 6.2e-82 usp6 T universal stress protein
HGHAFENF_00430 1e-199 bla2 3.5.2.6 V Beta-lactamase enzyme family
HGHAFENF_00431 3.3e-161 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HGHAFENF_00432 5.1e-295 glpQ3 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HGHAFENF_00433 5.4e-214 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HGHAFENF_00434 3.6e-188 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HGHAFENF_00435 3.5e-177 S Protein of unknown function (DUF2785)
HGHAFENF_00436 2.8e-168 hicD1 1.1.1.27 C Belongs to the LDH MDH superfamily
HGHAFENF_00437 6.5e-148 metQ M Belongs to the nlpA lipoprotein family
HGHAFENF_00438 1.4e-111 metI U ABC transporter permease
HGHAFENF_00439 4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HGHAFENF_00440 3.6e-48 gcsH2 E glycine cleavage
HGHAFENF_00441 9.3e-220 rodA D Belongs to the SEDS family
HGHAFENF_00442 3.3e-33 S Protein of unknown function (DUF2969)
HGHAFENF_00443 2.3e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HGHAFENF_00444 2.7e-180 mbl D Cell shape determining protein MreB Mrl
HGHAFENF_00445 2.1e-102 J Acetyltransferase (GNAT) domain
HGHAFENF_00446 4.4e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HGHAFENF_00447 1.1e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HGHAFENF_00448 2.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HGHAFENF_00449 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HGHAFENF_00450 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HGHAFENF_00451 1.8e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HGHAFENF_00452 6e-51 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HGHAFENF_00453 2.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HGHAFENF_00454 6.5e-128 atpB C it plays a direct role in the translocation of protons across the membrane
HGHAFENF_00455 1e-232 pyrP F Permease
HGHAFENF_00456 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HGHAFENF_00457 2.9e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HGHAFENF_00458 6.9e-192 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HGHAFENF_00459 1e-159 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HGHAFENF_00460 1.2e-197 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HGHAFENF_00461 1.2e-108 tdk 2.7.1.21 F thymidine kinase
HGHAFENF_00462 1.5e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HGHAFENF_00463 5.9e-137 cobQ S glutamine amidotransferase
HGHAFENF_00464 9.8e-196 manA 5.3.1.8 G mannose-6-phosphate isomerase
HGHAFENF_00465 1.4e-192 ampC V Beta-lactamase
HGHAFENF_00466 5.2e-29
HGHAFENF_00467 1e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HGHAFENF_00468 1.9e-58
HGHAFENF_00469 5.3e-125
HGHAFENF_00470 0.0 yfiC V ABC transporter
HGHAFENF_00471 0.0 ycfI V ABC transporter, ATP-binding protein
HGHAFENF_00472 3.3e-65 S Protein of unknown function (DUF1093)
HGHAFENF_00473 3.8e-135 yxkH G Polysaccharide deacetylase
HGHAFENF_00476 3.3e-37 S Haemolysin XhlA
HGHAFENF_00477 8.5e-202 lys M Glycosyl hydrolases family 25
HGHAFENF_00479 1.6e-71 S Protein of unknown function (DUF1617)
HGHAFENF_00480 0.0 sidC GT2,GT4 LM DNA recombination
HGHAFENF_00481 5e-60
HGHAFENF_00482 0.0 D NLP P60 protein
HGHAFENF_00483 8e-23
HGHAFENF_00484 6.3e-64
HGHAFENF_00485 2e-77 S Phage tail tube protein, TTP
HGHAFENF_00486 1.6e-53
HGHAFENF_00487 1e-88
HGHAFENF_00488 1.5e-50
HGHAFENF_00489 1.3e-51
HGHAFENF_00491 1e-174 S Phage major capsid protein E
HGHAFENF_00492 3.8e-49
HGHAFENF_00493 2.8e-16 S Domain of unknown function (DUF4355)
HGHAFENF_00495 2.4e-30
HGHAFENF_00496 1.7e-296 S Phage Mu protein F like protein
HGHAFENF_00497 9.7e-267 S Phage portal protein, SPP1 Gp6-like
HGHAFENF_00498 3.7e-240 ps334 S Terminase-like family
HGHAFENF_00499 6.4e-64 ps333 L Terminase small subunit
HGHAFENF_00500 5.1e-12
HGHAFENF_00503 3.8e-81 arpU S Phage transcriptional regulator, ArpU family
HGHAFENF_00504 5.4e-17
HGHAFENF_00506 5.9e-44
HGHAFENF_00509 1.3e-28 K Cro/C1-type HTH DNA-binding domain
HGHAFENF_00510 1.9e-14 S YjzC-like protein
HGHAFENF_00512 2.2e-66 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HGHAFENF_00513 8.1e-80
HGHAFENF_00514 2.7e-48
HGHAFENF_00515 3.4e-36 L Domain of unknown function (DUF4373)
HGHAFENF_00516 2.6e-63
HGHAFENF_00517 5.4e-55 S Bacteriophage Mu Gam like protein
HGHAFENF_00521 8e-80
HGHAFENF_00522 2.9e-53
HGHAFENF_00525 5.8e-26 K Cro/C1-type HTH DNA-binding domain
HGHAFENF_00526 1.7e-37 K sequence-specific DNA binding
HGHAFENF_00529 1.7e-39 yvaO K Helix-turn-helix domain
HGHAFENF_00530 5.7e-76 E IrrE N-terminal-like domain
HGHAFENF_00531 2.5e-87
HGHAFENF_00533 1.8e-69 S Domain of Unknown Function with PDB structure (DUF3862)
HGHAFENF_00536 4.1e-13 S DNA/RNA non-specific endonuclease
HGHAFENF_00540 1.5e-28 soj1 D Anion-transporting ATPase
HGHAFENF_00543 2.8e-218 int L Belongs to the 'phage' integrase family
HGHAFENF_00545 8.9e-30
HGHAFENF_00548 2.4e-57
HGHAFENF_00549 2.1e-39 S Phage gp6-like head-tail connector protein
HGHAFENF_00552 1.6e-277 S Caudovirus prohead serine protease
HGHAFENF_00553 8.8e-201 S Phage portal protein
HGHAFENF_00555 0.0 terL S overlaps another CDS with the same product name
HGHAFENF_00556 2.1e-82 terS L overlaps another CDS with the same product name
HGHAFENF_00557 5.4e-68 L HNH endonuclease
HGHAFENF_00558 3.7e-49 S head-tail joining protein
HGHAFENF_00560 3.5e-73
HGHAFENF_00561 2.3e-262 S Virulence-associated protein E
HGHAFENF_00562 5.5e-144 L DNA replication protein
HGHAFENF_00563 1.2e-27
HGHAFENF_00565 7.5e-17 K Transcriptional regulator
HGHAFENF_00566 7.3e-222 sip L Belongs to the 'phage' integrase family
HGHAFENF_00567 2e-38
HGHAFENF_00568 1.4e-43
HGHAFENF_00569 7.3e-83 K MarR family
HGHAFENF_00570 0.0 bztC D nuclear chromosome segregation
HGHAFENF_00571 1e-266 M MucBP domain
HGHAFENF_00572 2.7e-16
HGHAFENF_00573 7.2e-17
HGHAFENF_00574 5.2e-15
HGHAFENF_00575 1.1e-18
HGHAFENF_00576 1.6e-16
HGHAFENF_00577 1.9e-18
HGHAFENF_00578 1.6e-16
HGHAFENF_00579 0.0 msbA2 3.6.3.44 P ABC transporter transmembrane region
HGHAFENF_00580 2.9e-274 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HGHAFENF_00581 0.0 macB3 V ABC transporter, ATP-binding protein
HGHAFENF_00582 6.8e-24
HGHAFENF_00583 1e-259 pgi 5.3.1.9 G Belongs to the GPI family
HGHAFENF_00584 9.7e-155 glcU U sugar transport
HGHAFENF_00585 9.4e-217 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
HGHAFENF_00586 2.9e-287 yclK 2.7.13.3 T Histidine kinase
HGHAFENF_00587 8.9e-133 K response regulator
HGHAFENF_00588 3e-243 XK27_08635 S UPF0210 protein
HGHAFENF_00589 8.9e-38 gcvR T Belongs to the UPF0237 family
HGHAFENF_00590 2e-169 EG EamA-like transporter family
HGHAFENF_00592 7.7e-92 S ECF-type riboflavin transporter, S component
HGHAFENF_00593 2.5e-47
HGHAFENF_00594 1.1e-212 yceI EGP Major facilitator Superfamily
HGHAFENF_00595 5.5e-138 3.6.1.13, 3.6.1.55 F NUDIX domain
HGHAFENF_00596 3.8e-23
HGHAFENF_00598 2.9e-159 S Alpha/beta hydrolase of unknown function (DUF915)
HGHAFENF_00599 2.8e-173 ykfC 3.4.14.13 M NlpC/P60 family
HGHAFENF_00600 6.6e-81 K AsnC family
HGHAFENF_00601 2e-35
HGHAFENF_00602 5.1e-34
HGHAFENF_00603 7.8e-219 2.7.7.65 T diguanylate cyclase
HGHAFENF_00604 7.8e-296 S ABC transporter, ATP-binding protein
HGHAFENF_00605 2e-106 3.2.2.20 K acetyltransferase
HGHAFENF_00606 5.8e-82 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGHAFENF_00607 2.7e-39
HGHAFENF_00608 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
HGHAFENF_00609 3.4e-188 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HGHAFENF_00610 5e-162 degV S Uncharacterised protein, DegV family COG1307
HGHAFENF_00611 7.3e-231 hom1 1.1.1.3 E Homoserine dehydrogenase
HGHAFENF_00612 2.6e-244 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HGHAFENF_00613 3.6e-165 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HGHAFENF_00614 1.4e-176 XK27_08835 S ABC transporter
HGHAFENF_00615 8.7e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HGHAFENF_00616 6.4e-137 XK27_08845 S ABC transporter, ATP-binding protein
HGHAFENF_00617 1.4e-256 npr 1.11.1.1 C NADH oxidase
HGHAFENF_00618 1.5e-158 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HGHAFENF_00619 4.8e-137 terC P membrane
HGHAFENF_00620 2.4e-85 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HGHAFENF_00621 5.9e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HGHAFENF_00622 7.6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
HGHAFENF_00623 2.5e-58 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HGHAFENF_00624 3.8e-134 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HGHAFENF_00625 3.5e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HGHAFENF_00626 4.1e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HGHAFENF_00627 7.9e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HGHAFENF_00628 1.2e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HGHAFENF_00629 4.3e-118 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HGHAFENF_00630 1.3e-215 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HGHAFENF_00631 1.7e-164 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
HGHAFENF_00632 1.8e-215 ysaA V RDD family
HGHAFENF_00633 9.9e-166 corA P CorA-like Mg2+ transporter protein
HGHAFENF_00634 2.1e-55 S Domain of unknown function (DU1801)
HGHAFENF_00635 5.9e-91 rmeB K transcriptional regulator, MerR family
HGHAFENF_00636 4.2e-147 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
HGHAFENF_00637 8.6e-98 J glyoxalase III activity
HGHAFENF_00638 8e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HGHAFENF_00639 1.1e-186 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HGHAFENF_00640 3.7e-34
HGHAFENF_00641 9.2e-112 S Protein of unknown function (DUF1211)
HGHAFENF_00642 0.0 ydgH S MMPL family
HGHAFENF_00643 1.6e-288 M domain protein
HGHAFENF_00644 1.1e-74 yjcF S Acetyltransferase (GNAT) domain
HGHAFENF_00645 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HGHAFENF_00646 0.0 glpQ 3.1.4.46 C phosphodiesterase
HGHAFENF_00647 2.3e-184 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HGHAFENF_00648 2.3e-45 S Alpha/beta hydrolase of unknown function (DUF915)
HGHAFENF_00649 1.2e-73 S Alpha/beta hydrolase of unknown function (DUF915)
HGHAFENF_00650 3.6e-168 S Polyphosphate kinase 2 (PPK2)
HGHAFENF_00651 2.7e-97 drgA C Nitroreductase family
HGHAFENF_00652 3.1e-178 iunH2 3.2.2.1 F nucleoside hydrolase
HGHAFENF_00653 5.8e-150 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HGHAFENF_00654 8.8e-123 S Sucrose-6F-phosphate phosphohydrolase
HGHAFENF_00655 6.7e-157 ccpB 5.1.1.1 K lacI family
HGHAFENF_00656 8.1e-117 K Helix-turn-helix domain, rpiR family
HGHAFENF_00657 2.5e-175 S Oxidoreductase family, NAD-binding Rossmann fold
HGHAFENF_00658 5.9e-199 yhhX 1.1.1.371 S Oxidoreductase family, C-terminal alpha/beta domain
HGHAFENF_00659 0.0 yjcE P Sodium proton antiporter
HGHAFENF_00660 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HGHAFENF_00661 3.7e-107 pncA Q Isochorismatase family
HGHAFENF_00662 2.7e-132
HGHAFENF_00663 5.1e-125 skfE V ABC transporter
HGHAFENF_00664 9.5e-65 yvoA_1 K Transcriptional regulator, GntR family
HGHAFENF_00665 1.2e-45 S Enterocin A Immunity
HGHAFENF_00666 5.3e-175 D Alpha beta
HGHAFENF_00667 0.0 pepF2 E Oligopeptidase F
HGHAFENF_00668 1.3e-72 K Transcriptional regulator
HGHAFENF_00669 3e-164
HGHAFENF_00670 1.3e-57
HGHAFENF_00671 2.2e-47
HGHAFENF_00672 1.9e-124 yliE T Putative diguanylate phosphodiesterase
HGHAFENF_00673 6.7e-270 nox C NADH oxidase
HGHAFENF_00674 4.3e-163 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
HGHAFENF_00675 3.6e-245
HGHAFENF_00676 1.9e-204 S Protein conserved in bacteria
HGHAFENF_00677 6.8e-218 ydaM M Glycosyl transferase family group 2
HGHAFENF_00678 0.0 ydaN S Bacterial cellulose synthase subunit
HGHAFENF_00679 1e-132 2.7.7.65 T diguanylate cyclase activity
HGHAFENF_00680 1.7e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HGHAFENF_00681 2e-109 yviA S Protein of unknown function (DUF421)
HGHAFENF_00682 1.1e-61 S Protein of unknown function (DUF3290)
HGHAFENF_00683 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HGHAFENF_00684 3.3e-132 yliE T Putative diguanylate phosphodiesterase
HGHAFENF_00685 1.4e-259 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HGHAFENF_00686 1.1e-103 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HGHAFENF_00687 9.2e-212 norA EGP Major facilitator Superfamily
HGHAFENF_00688 1.2e-117 yfbR S HD containing hydrolase-like enzyme
HGHAFENF_00689 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HGHAFENF_00690 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HGHAFENF_00691 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HGHAFENF_00692 1.8e-231 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HGHAFENF_00693 7.2e-264 argH 4.3.2.1 E argininosuccinate lyase
HGHAFENF_00694 9.3e-87 S Short repeat of unknown function (DUF308)
HGHAFENF_00695 1.1e-161 rapZ S Displays ATPase and GTPase activities
HGHAFENF_00696 2.9e-190 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HGHAFENF_00697 3.7e-168 whiA K May be required for sporulation
HGHAFENF_00698 4.4e-305 oppA E ABC transporter, substratebinding protein
HGHAFENF_00699 3.9e-176 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGHAFENF_00700 3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HGHAFENF_00702 4.2e-245 rpoN K Sigma-54 factor, core binding domain
HGHAFENF_00703 7.3e-189 cggR K Putative sugar-binding domain
HGHAFENF_00704 2.6e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HGHAFENF_00705 8.1e-224 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HGHAFENF_00706 1.2e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HGHAFENF_00707 6.2e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HGHAFENF_00708 1.3e-133
HGHAFENF_00709 6.6e-295 clcA P chloride
HGHAFENF_00710 1.2e-30 secG U Preprotein translocase
HGHAFENF_00711 1.3e-139 est 3.1.1.1 S Serine aminopeptidase, S33
HGHAFENF_00712 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HGHAFENF_00713 9.3e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HGHAFENF_00714 0.0 3.4.21.72 M Bacterial Ig-like domain (group 3)
HGHAFENF_00715 7.2e-223 glnP P ABC transporter
HGHAFENF_00716 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HGHAFENF_00717 6.1e-105 yxjI
HGHAFENF_00718 4.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
HGHAFENF_00719 6.3e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HGHAFENF_00720 1.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HGHAFENF_00721 5e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HGHAFENF_00722 8.1e-88 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
HGHAFENF_00723 5.6e-100 dnaQ 2.7.7.7 L DNA polymerase III
HGHAFENF_00724 2.8e-153 xth 3.1.11.2 L exodeoxyribonuclease III
HGHAFENF_00725 3.9e-162 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HGHAFENF_00726 6.2e-168 murB 1.3.1.98 M Cell wall formation
HGHAFENF_00727 0.0 yjcE P Sodium proton antiporter
HGHAFENF_00728 1.3e-90 K helix_turn_helix multiple antibiotic resistance protein
HGHAFENF_00729 1.8e-119 S Protein of unknown function (DUF1361)
HGHAFENF_00730 2.7e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HGHAFENF_00731 1.6e-129 ybbR S YbbR-like protein
HGHAFENF_00732 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HGHAFENF_00733 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HGHAFENF_00734 1.3e-122 yliE T EAL domain
HGHAFENF_00735 6.4e-148 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
HGHAFENF_00736 7e-104 K Bacterial regulatory proteins, tetR family
HGHAFENF_00737 1.3e-206 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HGHAFENF_00738 1.5e-52
HGHAFENF_00739 1.5e-71
HGHAFENF_00740 3e-131 1.5.1.39 C nitroreductase
HGHAFENF_00741 9.2e-139 EGP Transmembrane secretion effector
HGHAFENF_00742 1.2e-33 G Transmembrane secretion effector
HGHAFENF_00743 4.8e-298 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HGHAFENF_00744 2.5e-141
HGHAFENF_00746 1.9e-71 spxA 1.20.4.1 P ArsC family
HGHAFENF_00747 1.5e-33
HGHAFENF_00748 1.1e-89 V VanZ like family
HGHAFENF_00749 1.8e-241 EGP Major facilitator Superfamily
HGHAFENF_00750 3.2e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HGHAFENF_00751 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HGHAFENF_00752 1.8e-289 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HGHAFENF_00753 5e-153 licD M LicD family
HGHAFENF_00754 1.3e-82 K Transcriptional regulator
HGHAFENF_00755 1.5e-19
HGHAFENF_00756 1.2e-225 pbuG S permease
HGHAFENF_00757 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HGHAFENF_00758 1.8e-153 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HGHAFENF_00759 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HGHAFENF_00760 5.4e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HGHAFENF_00761 2e-180 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HGHAFENF_00762 0.0 oatA I Acyltransferase
HGHAFENF_00763 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HGHAFENF_00764 5e-69 O OsmC-like protein
HGHAFENF_00765 5.8e-46
HGHAFENF_00766 8.2e-252 yfnA E Amino Acid
HGHAFENF_00767 2.5e-88
HGHAFENF_00768 9.9e-149 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HGHAFENF_00769 1.7e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HGHAFENF_00770 1.8e-19
HGHAFENF_00771 6.3e-105 gmk2 2.7.4.8 F Guanylate kinase
HGHAFENF_00772 1.3e-81 zur P Belongs to the Fur family
HGHAFENF_00773 7.1e-12 3.2.1.14 GH18
HGHAFENF_00774 8.4e-148
HGHAFENF_00776 2e-112 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HGHAFENF_00777 9.5e-209 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HGHAFENF_00778 3.3e-170 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGHAFENF_00779 3.6e-41
HGHAFENF_00780 9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HGHAFENF_00781 7.8e-149 glnH ET ABC transporter substrate-binding protein
HGHAFENF_00782 1.3e-108 gluC P ABC transporter permease
HGHAFENF_00783 4e-108 glnP P ABC transporter permease
HGHAFENF_00784 2.6e-83 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HGHAFENF_00785 1.8e-153 K CAT RNA binding domain
HGHAFENF_00786 1e-257 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
HGHAFENF_00787 4.6e-140 G YdjC-like protein
HGHAFENF_00788 2.4e-245 steT E amino acid
HGHAFENF_00789 4.8e-73 mgrA K helix_turn_helix multiple antibiotic resistance protein
HGHAFENF_00790 3.7e-149 XK27_00825 S Sulfite exporter TauE/SafE
HGHAFENF_00791 2e-71 K MarR family
HGHAFENF_00792 8.3e-210 EGP Major facilitator Superfamily
HGHAFENF_00793 3.8e-85 S membrane transporter protein
HGHAFENF_00794 7.1e-98 K Bacterial regulatory proteins, tetR family
HGHAFENF_00795 8.7e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HGHAFENF_00796 6.4e-78 3.6.1.55 F NUDIX domain
HGHAFENF_00797 1.3e-48 sugE U Multidrug resistance protein
HGHAFENF_00798 1.2e-26
HGHAFENF_00799 5.5e-129 pgm3 G Phosphoglycerate mutase family
HGHAFENF_00800 4.7e-125 pgm3 G Phosphoglycerate mutase family
HGHAFENF_00801 0.0 yjbQ P TrkA C-terminal domain protein
HGHAFENF_00802 3.1e-178 yqkA 3.6.1.55 F Belongs to the Nudix hydrolase family
HGHAFENF_00803 7.7e-112 dedA S SNARE associated Golgi protein
HGHAFENF_00804 0.0 helD 3.6.4.12 L DNA helicase
HGHAFENF_00805 1.7e-165 fabK 1.3.1.9 S Nitronate monooxygenase
HGHAFENF_00806 2.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
HGHAFENF_00807 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HGHAFENF_00809 5.1e-143 spoVK O ATPase family associated with various cellular activities (AAA)
HGHAFENF_00811 2.9e-45 L Helix-turn-helix domain
HGHAFENF_00812 2e-18 L hmm pf00665
HGHAFENF_00813 7.1e-29 L hmm pf00665
HGHAFENF_00814 8.9e-23 L hmm pf00665
HGHAFENF_00815 1.1e-78
HGHAFENF_00816 6.2e-50
HGHAFENF_00817 1.7e-63 K Helix-turn-helix XRE-family like proteins
HGHAFENF_00818 2e-110 XK27_07075 V CAAX protease self-immunity
HGHAFENF_00819 4.2e-56 hxlR K HxlR-like helix-turn-helix
HGHAFENF_00820 7.1e-234 EGP Major facilitator Superfamily
HGHAFENF_00821 6.7e-164 S Cysteine-rich secretory protein family
HGHAFENF_00822 7.4e-38 S MORN repeat
HGHAFENF_00823 0.0 XK27_09800 I Acyltransferase family
HGHAFENF_00824 7.1e-37 S Transglycosylase associated protein
HGHAFENF_00825 2.6e-84
HGHAFENF_00826 7.2e-23
HGHAFENF_00827 8.7e-72 asp S Asp23 family, cell envelope-related function
HGHAFENF_00828 5.3e-72 asp2 S Asp23 family, cell envelope-related function
HGHAFENF_00829 3.5e-146 Q Fumarylacetoacetate (FAA) hydrolase family
HGHAFENF_00830 1.1e-77 3.1.26.4 L RNA-DNA hybrid ribonuclease activity
HGHAFENF_00831 3.3e-161 vdlC S Belongs to the short-chain dehydrogenases reductases (SDR) family
HGHAFENF_00832 1e-173 rihC 3.2.2.1 F Nucleoside
HGHAFENF_00833 1.4e-69 accB 2.3.1.12 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HGHAFENF_00834 9.3e-80
HGHAFENF_00835 1.6e-82 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HGHAFENF_00836 1.1e-231 flhF N Uncharacterized conserved protein (DUF2075)
HGHAFENF_00837 8.8e-95 yxkA S Phosphatidylethanolamine-binding protein
HGHAFENF_00838 1.1e-54 ypaA S Protein of unknown function (DUF1304)
HGHAFENF_00839 1.5e-310 mco Q Multicopper oxidase
HGHAFENF_00840 4.6e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HGHAFENF_00841 6.3e-102 zmp1 O Zinc-dependent metalloprotease
HGHAFENF_00842 3.7e-44
HGHAFENF_00843 1.6e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HGHAFENF_00844 4.7e-241 amtB P ammonium transporter
HGHAFENF_00845 3.5e-258 P Major Facilitator Superfamily
HGHAFENF_00846 8.7e-93 K Transcriptional regulator PadR-like family
HGHAFENF_00847 3.8e-44
HGHAFENF_00848 1e-201 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HGHAFENF_00849 3.5e-154 tagG U Transport permease protein
HGHAFENF_00850 2.2e-218
HGHAFENF_00851 1.4e-223 mtnE 2.6.1.83 E Aminotransferase
HGHAFENF_00852 7.7e-148 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HGHAFENF_00853 1.3e-85 metI U Binding-protein-dependent transport system inner membrane component
HGHAFENF_00854 8.7e-126 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HGHAFENF_00855 2.2e-111 metQ P NLPA lipoprotein
HGHAFENF_00856 2.8e-60 S CHY zinc finger
HGHAFENF_00857 1e-176 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HGHAFENF_00858 6.8e-96 bioY S BioY family
HGHAFENF_00859 3e-40
HGHAFENF_00860 2.5e-280 pipD E Dipeptidase
HGHAFENF_00861 1.1e-29
HGHAFENF_00862 6.7e-122 qmcA O prohibitin homologues
HGHAFENF_00863 2.3e-240 xylP1 G MFS/sugar transport protein
HGHAFENF_00865 2.8e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HGHAFENF_00866 1.1e-256 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
HGHAFENF_00867 4.9e-190
HGHAFENF_00868 2e-163 ytrB V ABC transporter
HGHAFENF_00869 7e-59 ytrA K helix_turn_helix gluconate operon transcriptional repressor
HGHAFENF_00870 8.1e-22
HGHAFENF_00871 3e-90 K acetyltransferase
HGHAFENF_00872 1e-84 K GNAT family
HGHAFENF_00873 1.1e-83 6.3.3.2 S ASCH
HGHAFENF_00874 1.1e-95 puuR K Cupin domain
HGHAFENF_00875 3.5e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HGHAFENF_00876 2.7e-149 potB P ABC transporter permease
HGHAFENF_00877 3.4e-141 potC P ABC transporter permease
HGHAFENF_00878 5.2e-206 potD P ABC transporter
HGHAFENF_00879 7.1e-21 U Preprotein translocase subunit SecB
HGHAFENF_00880 2.2e-30
HGHAFENF_00881 2.5e-08 S Motility quorum-sensing regulator, toxin of MqsA
HGHAFENF_00882 2.6e-37
HGHAFENF_00883 3e-226 ndh 1.6.99.3 C NADH dehydrogenase
HGHAFENF_00884 1.7e-75 K Transcriptional regulator
HGHAFENF_00885 3.8e-78 elaA S GNAT family
HGHAFENF_00886 3.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HGHAFENF_00887 6.8e-57
HGHAFENF_00888 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
HGHAFENF_00889 1.3e-131
HGHAFENF_00890 5.3e-175 sepS16B
HGHAFENF_00891 7.4e-67 gcvH E Glycine cleavage H-protein
HGHAFENF_00892 2.8e-50 lytE M LysM domain protein
HGHAFENF_00893 8.5e-52 M Lysin motif
HGHAFENF_00894 1.6e-118 S CAAX protease self-immunity
HGHAFENF_00895 1.6e-113 V CAAX protease self-immunity
HGHAFENF_00896 7.1e-121 yclH V ABC transporter
HGHAFENF_00897 4.6e-181 yclI V MacB-like periplasmic core domain
HGHAFENF_00898 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
HGHAFENF_00899 4.2e-106 tag 3.2.2.20 L glycosylase
HGHAFENF_00900 0.0 ydgH S MMPL family
HGHAFENF_00901 1.2e-103 K transcriptional regulator
HGHAFENF_00902 2.7e-123 2.7.6.5 S RelA SpoT domain protein
HGHAFENF_00903 1.3e-47
HGHAFENF_00904 2e-258 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
HGHAFENF_00905 1.6e-183 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HGHAFENF_00906 2.1e-41
HGHAFENF_00907 9.9e-57
HGHAFENF_00908 1e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGHAFENF_00909 2.1e-129 yidA K Helix-turn-helix domain, rpiR family
HGHAFENF_00910 1.8e-49
HGHAFENF_00911 6.4e-128 K Transcriptional regulatory protein, C terminal
HGHAFENF_00912 6.8e-251 T PhoQ Sensor
HGHAFENF_00913 3.3e-65 K helix_turn_helix, mercury resistance
HGHAFENF_00914 9.7e-253 ydiC1 EGP Major facilitator Superfamily
HGHAFENF_00915 1e-40
HGHAFENF_00916 5.2e-42
HGHAFENF_00917 5.5e-118
HGHAFENF_00918 8.5e-233 mntH P H( )-stimulated, divalent metal cation uptake system
HGHAFENF_00919 5.7e-121 K Bacterial regulatory proteins, tetR family
HGHAFENF_00920 1.8e-72 K Transcriptional regulator
HGHAFENF_00921 1.3e-69
HGHAFENF_00922 6.3e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HGHAFENF_00923 1.4e-144
HGHAFENF_00924 0.0 pts4ABC 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
HGHAFENF_00925 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
HGHAFENF_00926 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HGHAFENF_00927 3.5e-129 treR K UTRA
HGHAFENF_00928 1.7e-42
HGHAFENF_00929 7.3e-43 S Protein of unknown function (DUF2089)
HGHAFENF_00930 4.3e-141 pnuC H nicotinamide mononucleotide transporter
HGHAFENF_00931 7.8e-159 map 3.4.11.18 E Methionine Aminopeptidase
HGHAFENF_00932 4.5e-166 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HGHAFENF_00933 9.8e-211 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HGHAFENF_00934 6.1e-94 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
HGHAFENF_00935 3.5e-97 yieF S NADPH-dependent FMN reductase
HGHAFENF_00936 2.2e-254 S Uncharacterized protein conserved in bacteria (DUF2252)
HGHAFENF_00937 5e-81 ndk 2.7.4.6 F Belongs to the NDK family
HGHAFENF_00938 2e-62
HGHAFENF_00939 6.6e-96
HGHAFENF_00940 6.1e-49
HGHAFENF_00941 6.2e-57 trxA1 O Belongs to the thioredoxin family
HGHAFENF_00942 2.1e-73
HGHAFENF_00943 2.8e-221 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HGHAFENF_00944 1.7e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGHAFENF_00945 0.0 mtlR K Mga helix-turn-helix domain
HGHAFENF_00946 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
HGHAFENF_00947 3.9e-278 pipD E Dipeptidase
HGHAFENF_00948 4.8e-99 K Helix-turn-helix domain
HGHAFENF_00949 1.3e-223 1.3.5.4 C FAD dependent oxidoreductase
HGHAFENF_00950 4.5e-174 P Major Facilitator Superfamily
HGHAFENF_00951 7.4e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HGHAFENF_00952 4.7e-31 ygzD K Transcriptional
HGHAFENF_00953 4.3e-68
HGHAFENF_00954 4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HGHAFENF_00955 4.1e-158 dkgB S reductase
HGHAFENF_00956 6.9e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HGHAFENF_00957 3.1e-101 S ABC transporter permease
HGHAFENF_00958 2e-258 P ABC transporter
HGHAFENF_00959 1.5e-115 P cobalt transport
HGHAFENF_00960 2.4e-61
HGHAFENF_00961 5.5e-254 S ATPases associated with a variety of cellular activities
HGHAFENF_00962 8.5e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HGHAFENF_00963 3.5e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HGHAFENF_00965 4.5e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HGHAFENF_00966 3.8e-162 FbpA K Domain of unknown function (DUF814)
HGHAFENF_00967 1.3e-60 S Domain of unknown function (DU1801)
HGHAFENF_00968 4.9e-34
HGHAFENF_00969 1e-179 yghZ C Aldo keto reductase family protein
HGHAFENF_00970 6.7e-113 pgm1 G phosphoglycerate mutase
HGHAFENF_00971 7e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HGHAFENF_00972 2.3e-215 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGHAFENF_00973 2.6e-79 yiaC K Acetyltransferase (GNAT) domain
HGHAFENF_00974 7.8e-310 oppA E ABC transporter, substratebinding protein
HGHAFENF_00975 0.0 oppA E ABC transporter, substratebinding protein
HGHAFENF_00976 2.1e-157 hipB K Helix-turn-helix
HGHAFENF_00978 0.0 3.6.4.13 M domain protein
HGHAFENF_00979 7.7e-166 mleR K LysR substrate binding domain
HGHAFENF_00980 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HGHAFENF_00981 1.1e-217 nhaC C Na H antiporter NhaC
HGHAFENF_00982 1.3e-165 3.5.1.10 C nadph quinone reductase
HGHAFENF_00983 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HGHAFENF_00984 9.1e-173 scrR K Transcriptional regulator, LacI family
HGHAFENF_00985 1.4e-305 scrB 3.2.1.26 GH32 G invertase
HGHAFENF_00986 0.0 scrA 2.7.1.193, 2.7.1.211, 5.3.1.1 G phosphotransferase system
HGHAFENF_00987 1.8e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HGHAFENF_00988 1.5e-45 ygbF S Sugar efflux transporter for intercellular exchange
HGHAFENF_00989 0.0 3.2.1.96 G Glycosyl hydrolase family 85
HGHAFENF_00990 1.6e-122 K Helix-turn-helix XRE-family like proteins
HGHAFENF_00991 2.8e-82 gtrA S GtrA-like protein
HGHAFENF_00992 1.7e-113 zmp3 O Zinc-dependent metalloprotease
HGHAFENF_00993 7e-33
HGHAFENF_00995 1.2e-211 livJ E Receptor family ligand binding region
HGHAFENF_00996 6.5e-154 livH U Branched-chain amino acid transport system / permease component
HGHAFENF_00997 9e-141 livM E Branched-chain amino acid transport system / permease component
HGHAFENF_00998 1.8e-139 livG E Branched-chain amino acid ATP-binding cassette transporter
HGHAFENF_00999 9.5e-124 livF E ABC transporter
HGHAFENF_01000 1.2e-87 acuB S Domain in cystathionine beta-synthase and other proteins.
HGHAFENF_01001 1e-91 S WxL domain surface cell wall-binding
HGHAFENF_01002 3.6e-188 S Cell surface protein
HGHAFENF_01003 8.2e-61
HGHAFENF_01004 1e-260
HGHAFENF_01005 3.5e-169 XK27_00670 S ABC transporter
HGHAFENF_01006 2.4e-152 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
HGHAFENF_01007 8.1e-109 cmpC S ATPases associated with a variety of cellular activities
HGHAFENF_01008 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
HGHAFENF_01009 5e-119 drgA C Nitroreductase family
HGHAFENF_01010 2.9e-96 rmaB K Transcriptional regulator, MarR family
HGHAFENF_01011 0.0 lmrA 3.6.3.44 V ABC transporter
HGHAFENF_01012 2.9e-162 ypbG 2.7.1.2 GK ROK family
HGHAFENF_01013 1.4e-47 3.6.4.12 K HxlR-like helix-turn-helix
HGHAFENF_01014 2.1e-111 K Transcriptional regulator C-terminal region
HGHAFENF_01015 7.5e-177 4.1.1.52 S Amidohydrolase
HGHAFENF_01016 4.4e-129 E lipolytic protein G-D-S-L family
HGHAFENF_01017 1.1e-159 yicL EG EamA-like transporter family
HGHAFENF_01018 2.1e-223 sdrF M Collagen binding domain
HGHAFENF_01019 9.7e-269 I acetylesterase activity
HGHAFENF_01020 5.2e-177 S Phosphotransferase system, EIIC
HGHAFENF_01021 2.7e-137 aroD S Alpha/beta hydrolase family
HGHAFENF_01022 3.2e-37
HGHAFENF_01024 8.8e-136 S zinc-ribbon domain
HGHAFENF_01025 6e-266 S response to antibiotic
HGHAFENF_01026 3.7e-287 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HGHAFENF_01027 2.4e-243 P Sodium:sulfate symporter transmembrane region
HGHAFENF_01028 2.2e-165 K LysR substrate binding domain
HGHAFENF_01029 4.4e-79
HGHAFENF_01030 4.9e-22
HGHAFENF_01031 1.5e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HGHAFENF_01032 6.8e-192 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HGHAFENF_01033 4.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HGHAFENF_01034 2e-80
HGHAFENF_01035 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HGHAFENF_01036 2.2e-104 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HGHAFENF_01037 3.1e-127 yliE T EAL domain
HGHAFENF_01038 6.2e-218 2.7.7.65 T Diguanylate cyclase, GGDEF domain
HGHAFENF_01039 1.7e-88 pts21A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HGHAFENF_01040 5.6e-39 S Cytochrome B5
HGHAFENF_01041 1.6e-237
HGHAFENF_01042 7e-130 treR K UTRA
HGHAFENF_01043 2e-160 I alpha/beta hydrolase fold
HGHAFENF_01044 1.6e-254 npp S type I phosphodiesterase nucleotide pyrophosphatase
HGHAFENF_01045 1.5e-233 yxiO S Vacuole effluxer Atg22 like
HGHAFENF_01046 9.3e-172 ropB K Helix-turn-helix XRE-family like proteins
HGHAFENF_01047 1.1e-207 EGP Major facilitator Superfamily
HGHAFENF_01048 0.0 uvrA3 L excinuclease ABC
HGHAFENF_01049 0.0 S Predicted membrane protein (DUF2207)
HGHAFENF_01050 2.4e-147 3.1.3.102, 3.1.3.104 S hydrolase
HGHAFENF_01051 7.1e-308 ybiT S ABC transporter, ATP-binding protein
HGHAFENF_01052 1.7e-221 S CAAX protease self-immunity
HGHAFENF_01053 5.7e-97 2.3.1.128 J Acetyltransferase (GNAT) domain
HGHAFENF_01054 2.1e-102 speG J Acetyltransferase (GNAT) domain
HGHAFENF_01055 8.8e-141 endA F DNA RNA non-specific endonuclease
HGHAFENF_01056 1.4e-53 K helix_turn_helix, Arsenical Resistance Operon Repressor
HGHAFENF_01057 1.1e-95 K Transcriptional regulator (TetR family)
HGHAFENF_01058 1.6e-176 yhgE V domain protein
HGHAFENF_01059 6.4e-08
HGHAFENF_01061 7.4e-245 EGP Major facilitator Superfamily
HGHAFENF_01062 0.0 mdlA V ABC transporter
HGHAFENF_01063 0.0 mdlB V ABC transporter
HGHAFENF_01065 6.3e-193 C Aldo/keto reductase family
HGHAFENF_01066 9.7e-102 M Protein of unknown function (DUF3737)
HGHAFENF_01067 5.7e-222 patB 4.4.1.8 E Aminotransferase, class I
HGHAFENF_01068 3.9e-102 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HGHAFENF_01069 1.5e-81
HGHAFENF_01070 1.1e-124 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HGHAFENF_01071 5.8e-95 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
HGHAFENF_01072 6.1e-76 T Belongs to the universal stress protein A family
HGHAFENF_01073 5.7e-83 GM NAD(P)H-binding
HGHAFENF_01074 1.3e-142 EGP Major Facilitator Superfamily
HGHAFENF_01075 1.5e-142 akr5f 1.1.1.346 S reductase
HGHAFENF_01076 1.3e-130 C Aldo keto reductase
HGHAFENF_01077 9.4e-114 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HGHAFENF_01078 4.4e-10 adhR K helix_turn_helix, mercury resistance
HGHAFENF_01079 1.8e-25 fldA C Flavodoxin
HGHAFENF_01081 2e-78 K Transcriptional regulator
HGHAFENF_01082 5.6e-105 akr5f 1.1.1.346 S reductase
HGHAFENF_01083 1.3e-87 GM NAD(P)H-binding
HGHAFENF_01084 4.9e-82 glcU U sugar transport
HGHAFENF_01085 3e-126 IQ reductase
HGHAFENF_01086 2.5e-76 darA C Flavodoxin
HGHAFENF_01087 6.3e-81 yiiE S Protein of unknown function (DUF1211)
HGHAFENF_01088 1.1e-142 aRA11 1.1.1.346 S reductase
HGHAFENF_01089 3.2e-150 IQ Enoyl-(Acyl carrier protein) reductase
HGHAFENF_01090 2.3e-195 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HGHAFENF_01091 1.2e-103 GM NAD(P)H-binding
HGHAFENF_01092 2.8e-157 K LysR substrate binding domain
HGHAFENF_01093 8.4e-60 S Domain of unknown function (DUF4440)
HGHAFENF_01094 1.2e-112 pgm8 G Histidine phosphatase superfamily (branch 1)
HGHAFENF_01095 8.2e-48
HGHAFENF_01096 7e-37
HGHAFENF_01097 7.3e-86 yvbK 3.1.3.25 K GNAT family
HGHAFENF_01098 2.4e-83
HGHAFENF_01099 8.4e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HGHAFENF_01100 2.2e-100 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HGHAFENF_01101 8e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HGHAFENF_01103 3.7e-120 macB V ABC transporter, ATP-binding protein
HGHAFENF_01104 0.0 ylbB V ABC transporter permease
HGHAFENF_01105 2.3e-237 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HGHAFENF_01106 1.7e-78 K transcriptional regulator, MerR family
HGHAFENF_01107 9.3e-76 yphH S Cupin domain
HGHAFENF_01108 5.6e-55 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
HGHAFENF_01109 6.7e-128 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HGHAFENF_01110 4.7e-211 natB CP ABC-2 family transporter protein
HGHAFENF_01111 1.1e-167 natA S ABC transporter, ATP-binding protein
HGHAFENF_01112 5.2e-92 ogt 2.1.1.63 L Methyltransferase
HGHAFENF_01113 7e-54 lytE M LysM domain
HGHAFENF_01115 5.3e-268 tagE6 2.4.1.52 GT4 M Glycosyl transferases group 1
HGHAFENF_01116 2.4e-297 tagE5 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
HGHAFENF_01117 3.7e-151 rlrG K Transcriptional regulator
HGHAFENF_01118 9.3e-173 S Conserved hypothetical protein 698
HGHAFENF_01119 2.1e-102 rimL J Acetyltransferase (GNAT) domain
HGHAFENF_01120 1.4e-76 S Domain of unknown function (DUF4811)
HGHAFENF_01121 1.6e-269 lmrB EGP Major facilitator Superfamily
HGHAFENF_01122 1.9e-126 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HGHAFENF_01123 4.2e-180 ynfM EGP Major facilitator Superfamily
HGHAFENF_01124 8.5e-257 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
HGHAFENF_01125 1.2e-155 mleP3 S Membrane transport protein
HGHAFENF_01126 6.4e-109 S Membrane
HGHAFENF_01127 4.1e-188 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HGHAFENF_01128 8.1e-99 1.5.1.3 H RibD C-terminal domain
HGHAFENF_01129 1.4e-186 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HGHAFENF_01130 3.7e-91 2.7.7.65 T phosphorelay sensor kinase activity
HGHAFENF_01131 5.6e-121 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HGHAFENF_01132 5.2e-174 hrtB V ABC transporter permease
HGHAFENF_01133 6.6e-95 S Protein of unknown function (DUF1440)
HGHAFENF_01134 1.7e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HGHAFENF_01135 6.4e-148 KT helix_turn_helix, mercury resistance
HGHAFENF_01136 1.6e-115 S Protein of unknown function (DUF554)
HGHAFENF_01137 1.1e-92 yueI S Protein of unknown function (DUF1694)
HGHAFENF_01138 2e-143 yvpB S Peptidase_C39 like family
HGHAFENF_01139 4e-152 M Glycosyl hydrolases family 25
HGHAFENF_01140 1e-111
HGHAFENF_01141 1.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HGHAFENF_01142 1.8e-84 hmpT S Pfam:DUF3816
HGHAFENF_01143 1.6e-32 copZ P Heavy-metal-associated domain
HGHAFENF_01144 4.3e-118 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HGHAFENF_01145 0.0 pepO 3.4.24.71 O Peptidase family M13
HGHAFENF_01146 1.9e-83 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HGHAFENF_01147 1.3e-262 nox C NADH oxidase
HGHAFENF_01148 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
HGHAFENF_01149 1.4e-163 S Cell surface protein
HGHAFENF_01150 1.5e-118 S WxL domain surface cell wall-binding
HGHAFENF_01151 2.3e-99 S WxL domain surface cell wall-binding
HGHAFENF_01152 4.6e-45
HGHAFENF_01153 2.7e-103 K Bacterial regulatory proteins, tetR family
HGHAFENF_01154 1.5e-49
HGHAFENF_01155 1.4e-248 S Putative metallopeptidase domain
HGHAFENF_01156 5.4e-220 3.1.3.1 S associated with various cellular activities
HGHAFENF_01157 1.8e-108 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
HGHAFENF_01158 0.0 ubiB S ABC1 family
HGHAFENF_01159 4.5e-250 brnQ U Component of the transport system for branched-chain amino acids
HGHAFENF_01160 0.0 lacS G Transporter
HGHAFENF_01161 0.0 lacA 3.2.1.23 G -beta-galactosidase
HGHAFENF_01162 1.6e-188 lacR K Transcriptional regulator
HGHAFENF_01163 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HGHAFENF_01164 3.6e-230 mdtH P Sugar (and other) transporter
HGHAFENF_01165 2.3e-303 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HGHAFENF_01166 8.6e-232 EGP Major facilitator Superfamily
HGHAFENF_01167 7.4e-183 rhaR K helix_turn_helix, arabinose operon control protein
HGHAFENF_01168 5e-100 fic D Fic/DOC family
HGHAFENF_01169 1.6e-76 K Helix-turn-helix XRE-family like proteins
HGHAFENF_01170 2e-183 galR K Transcriptional regulator
HGHAFENF_01171 1.3e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HGHAFENF_01172 8.9e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HGHAFENF_01173 9.3e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HGHAFENF_01174 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HGHAFENF_01175 7e-186 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HGHAFENF_01176 0.0 rafA 3.2.1.22 G alpha-galactosidase
HGHAFENF_01177 0.0 lacS G Transporter
HGHAFENF_01178 4.1e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HGHAFENF_01179 1.1e-173 galR K Transcriptional regulator
HGHAFENF_01180 2.6e-194 C Aldo keto reductase family protein
HGHAFENF_01181 3.1e-65 S pyridoxamine 5-phosphate
HGHAFENF_01182 1.1e-74 1.3.5.4 C FAD binding domain
HGHAFENF_01183 0.0 1.3.5.4 C FAD binding domain
HGHAFENF_01184 4.8e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HGHAFENF_01185 2.4e-133 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HGHAFENF_01186 2.5e-166 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HGHAFENF_01187 9.2e-175 K Transcriptional regulator, LysR family
HGHAFENF_01188 1.2e-219 ydiN EGP Major Facilitator Superfamily
HGHAFENF_01189 5e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HGHAFENF_01190 9.4e-161 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HGHAFENF_01191 1e-156 IQ Enoyl-(Acyl carrier protein) reductase
HGHAFENF_01192 2.3e-164 G Xylose isomerase-like TIM barrel
HGHAFENF_01193 4.7e-168 K Transcriptional regulator, LysR family
HGHAFENF_01194 1.2e-201 EGP Major Facilitator Superfamily
HGHAFENF_01195 7.6e-64
HGHAFENF_01196 1.8e-155 estA S Putative esterase
HGHAFENF_01197 1.2e-134 K UTRA domain
HGHAFENF_01198 3.6e-249 pts29C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGHAFENF_01199 8.8e-165 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HGHAFENF_01200 2.6e-158 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
HGHAFENF_01201 1.1e-211 S Bacterial protein of unknown function (DUF871)
HGHAFENF_01202 5.5e-291 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HGHAFENF_01203 0.0 pts30BCA 2.7.1.193, 2.7.1.211 G phosphotransferase system
HGHAFENF_01204 3.6e-154 licT K CAT RNA binding domain
HGHAFENF_01205 0.0 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HGHAFENF_01206 3.2e-225 malY 4.4.1.8 E Aminotransferase class I and II
HGHAFENF_01207 4.5e-269 frvB 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
HGHAFENF_01208 3.3e-74 ptsN 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HGHAFENF_01209 3.7e-79 ptsG 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HGHAFENF_01210 1.3e-137 yleF K Helix-turn-helix domain, rpiR family
HGHAFENF_01211 7.2e-246 sacX 2.7.1.193, 2.7.1.211 G phosphotransferase system
HGHAFENF_01212 5.4e-156 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HGHAFENF_01213 1.8e-198 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HGHAFENF_01214 3.1e-294 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HGHAFENF_01215 1.9e-291 pbg10 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HGHAFENF_01216 0.0 bglP 2.7.1.193, 2.7.1.211 G phosphotransferase system
HGHAFENF_01217 3.8e-159 licT K CAT RNA binding domain
HGHAFENF_01218 0.0 treP 2.4.1.64 GH65 G hydrolase, family 65, central catalytic
HGHAFENF_01219 1.1e-173 K Transcriptional regulator, LacI family
HGHAFENF_01220 1.8e-270 G Major Facilitator
HGHAFENF_01221 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HGHAFENF_01223 1.3e-174 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HGHAFENF_01224 3e-145 yxeH S hydrolase
HGHAFENF_01225 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HGHAFENF_01226 1.6e-112 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HGHAFENF_01227 3.2e-240 ulaA 2.7.1.194 S PTS system sugar-specific permease component
HGHAFENF_01228 2.2e-45 ulaB 2.7.1.194, 2.7.1.200 G Phosphotransferase system galactitol-specific IIB component
HGHAFENF_01229 7.4e-77 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HGHAFENF_01230 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HGHAFENF_01231 1.3e-113 gph 3.1.3.18 S Haloacid dehalogenase-like hydrolase
HGHAFENF_01232 3e-188 gutB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
HGHAFENF_01233 1.1e-231 gatC G PTS system sugar-specific permease component
HGHAFENF_01234 1.1e-44 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HGHAFENF_01235 3.3e-80 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HGHAFENF_01236 5.2e-123 K DeoR C terminal sensor domain
HGHAFENF_01237 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HGHAFENF_01238 7.6e-70 yueI S Protein of unknown function (DUF1694)
HGHAFENF_01239 9.6e-103 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
HGHAFENF_01240 3.9e-265 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HGHAFENF_01241 1e-136 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HGHAFENF_01242 3e-306 araB 2.7.1.12, 2.7.1.16, 2.7.1.5 G carbohydrate kinase FGGY
HGHAFENF_01243 1.6e-255 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HGHAFENF_01244 3.1e-206 araR K Transcriptional regulator
HGHAFENF_01245 6.7e-122 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HGHAFENF_01246 4.2e-228 1.7.1.15 S Pyridine nucleotide-disulphide oxidoreductase
HGHAFENF_01247 4.2e-70 S Pyrimidine dimer DNA glycosylase
HGHAFENF_01248 4.5e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
HGHAFENF_01249 3.6e-11
HGHAFENF_01250 9e-13 ytgB S Transglycosylase associated protein
HGHAFENF_01251 1.6e-290 katA 1.11.1.6 C Belongs to the catalase family
HGHAFENF_01252 4.9e-78 yneH 1.20.4.1 K ArsC family
HGHAFENF_01253 2.8e-134 K LytTr DNA-binding domain
HGHAFENF_01254 8.7e-160 2.7.13.3 T GHKL domain
HGHAFENF_01255 1.8e-12
HGHAFENF_01256 2.4e-67 agrB KOT May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HGHAFENF_01257 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
HGHAFENF_01259 6.1e-202 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HGHAFENF_01260 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HGHAFENF_01261 8.7e-72 K Transcriptional regulator
HGHAFENF_01262 0.0 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HGHAFENF_01263 1.1e-71 yueI S Protein of unknown function (DUF1694)
HGHAFENF_01264 1e-125 S Membrane
HGHAFENF_01265 1.3e-164 rhaD 4.1.2.17, 4.1.2.19, 5.1.3.4 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HGHAFENF_01266 1.3e-256 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
HGHAFENF_01267 5e-56 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HGHAFENF_01268 1.8e-286 rhaB 2.7.1.12, 2.7.1.16, 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HGHAFENF_01269 7.8e-244 iolF EGP Major facilitator Superfamily
HGHAFENF_01270 9.8e-152 S hydrolase
HGHAFENF_01271 1.8e-81
HGHAFENF_01272 6.5e-122 pgm7 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HGHAFENF_01273 6.8e-141 epsV 2.7.8.12 S glycosyl transferase family 2
HGHAFENF_01274 1.8e-130 gntR K UTRA
HGHAFENF_01275 2.3e-48 pts20B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HGHAFENF_01276 5.1e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
HGHAFENF_01277 9.5e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HGHAFENF_01278 1.8e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HGHAFENF_01279 1.1e-245 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HGHAFENF_01280 8.2e-134 V AAA domain, putative AbiEii toxin, Type IV TA system
HGHAFENF_01281 3.2e-154 V ABC transporter
HGHAFENF_01282 1.3e-117 K Transcriptional regulator
HGHAFENF_01283 8.6e-265 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HGHAFENF_01284 3.6e-88 niaR S 3H domain
HGHAFENF_01285 2.1e-232 S Sterol carrier protein domain
HGHAFENF_01286 3.8e-212 S Bacterial protein of unknown function (DUF871)
HGHAFENF_01287 1.8e-36 XK27_01315 S Protein of unknown function (DUF2829)
HGHAFENF_01288 7.5e-135 IQ Enoyl-(Acyl carrier protein) reductase
HGHAFENF_01289 7.8e-69 FG Scavenger mRNA decapping enzyme C-term binding
HGHAFENF_01290 3.1e-101 3.6.1.13 L Belongs to the Nudix hydrolase family
HGHAFENF_01291 1.7e-111 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HGHAFENF_01292 9.8e-11 mcbG S Pentapeptide repeats (8 copies)
HGHAFENF_01293 8.5e-145 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
HGHAFENF_01294 2.6e-280 thrC 4.2.3.1 E Threonine synthase
HGHAFENF_01295 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HGHAFENF_01297 5.7e-52
HGHAFENF_01298 5.4e-118
HGHAFENF_01299 7.3e-86 2.7.7.1, 3.6.1.55 F belongs to the nudix hydrolase family
HGHAFENF_01300 1.7e-234 malY 4.4.1.8 E Aminotransferase, class I
HGHAFENF_01302 2.1e-49
HGHAFENF_01303 1.1e-88
HGHAFENF_01304 4.2e-71 gtcA S Teichoic acid glycosylation protein
HGHAFENF_01305 1.2e-35
HGHAFENF_01306 6.7e-81 uspA T universal stress protein
HGHAFENF_01307 2.9e-148
HGHAFENF_01308 6.9e-164 V ABC transporter, ATP-binding protein
HGHAFENF_01309 7.9e-61 gntR1 K Transcriptional regulator, GntR family
HGHAFENF_01310 3e-41
HGHAFENF_01311 0.0 V FtsX-like permease family
HGHAFENF_01312 2.3e-139 cysA V ABC transporter, ATP-binding protein
HGHAFENF_01313 1.5e-180 ansA 3.5.1.1 EJ Asparaginase
HGHAFENF_01314 1.1e-147 S Alpha/beta hydrolase of unknown function (DUF915)
HGHAFENF_01315 1.9e-118 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
HGHAFENF_01316 1.2e-146 ptp3 3.1.3.48 T Tyrosine phosphatase family
HGHAFENF_01317 1.4e-189 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
HGHAFENF_01318 1.8e-110 XK27_09620 1.3.5.4 S NADPH-dependent FMN reductase
HGHAFENF_01319 1.5e-223 XK27_09615 1.3.5.4 S reductase
HGHAFENF_01320 1.7e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HGHAFENF_01321 1.9e-211 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HGHAFENF_01322 2.9e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HGHAFENF_01323 3.6e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGHAFENF_01324 2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGHAFENF_01325 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGHAFENF_01326 1.1e-280 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HGHAFENF_01327 2.7e-188 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HGHAFENF_01328 2.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HGHAFENF_01329 7.3e-286 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HGHAFENF_01330 6.4e-216 purD 6.3.4.13 F Belongs to the GARS family
HGHAFENF_01331 6.9e-124 2.1.1.14 E Methionine synthase
HGHAFENF_01332 9.2e-253 pgaC GT2 M Glycosyl transferase
HGHAFENF_01333 2.6e-94
HGHAFENF_01334 6.5e-156 T EAL domain
HGHAFENF_01335 3.9e-162 GM NmrA-like family
HGHAFENF_01336 2.4e-221 pbuG S Permease family
HGHAFENF_01337 3e-235 pbuX F xanthine permease
HGHAFENF_01338 2.5e-242 pucR QT Purine catabolism regulatory protein-like family
HGHAFENF_01339 5e-47 pucR QT Purine catabolism regulatory protein-like family
HGHAFENF_01340 1.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HGHAFENF_01341 1.2e-171 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HGHAFENF_01342 1.5e-244 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HGHAFENF_01343 1.5e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HGHAFENF_01344 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HGHAFENF_01345 9.7e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HGHAFENF_01346 1.8e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HGHAFENF_01347 1.4e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HGHAFENF_01348 4.6e-169 ydcZ S Putative inner membrane exporter, YdcZ
HGHAFENF_01349 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HGHAFENF_01350 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HGHAFENF_01351 8.2e-96 wecD K Acetyltransferase (GNAT) family
HGHAFENF_01352 5.6e-115 ylbE GM NAD(P)H-binding
HGHAFENF_01353 1.9e-161 mleR K LysR family
HGHAFENF_01354 1.7e-126 S membrane transporter protein
HGHAFENF_01355 3e-18
HGHAFENF_01356 7.8e-160 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HGHAFENF_01357 1.4e-217 patA 2.6.1.1 E Aminotransferase
HGHAFENF_01358 5.5e-261 gabR K Bacterial regulatory proteins, gntR family
HGHAFENF_01359 6.3e-295 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HGHAFENF_01360 8.5e-57 S SdpI/YhfL protein family
HGHAFENF_01361 1.8e-173 C Zinc-binding dehydrogenase
HGHAFENF_01362 2.5e-62 K helix_turn_helix, mercury resistance
HGHAFENF_01363 1.5e-211 yttB EGP Major facilitator Superfamily
HGHAFENF_01364 8.4e-269 yjcE P Sodium proton antiporter
HGHAFENF_01365 4.9e-87 nrdI F Belongs to the NrdI family
HGHAFENF_01366 1.2e-239 yhdP S Transporter associated domain
HGHAFENF_01367 4.4e-58
HGHAFENF_01368 4.1e-74 hspX O Belongs to the small heat shock protein (HSP20) family
HGHAFENF_01369 7.7e-61
HGHAFENF_01370 4.2e-92 M1-874 K Domain of unknown function (DUF1836)
HGHAFENF_01371 5.5e-138 rrp8 K LytTr DNA-binding domain
HGHAFENF_01372 3.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HGHAFENF_01373 5.8e-138
HGHAFENF_01374 5.8e-91 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HGHAFENF_01375 2.4e-130 gntR2 K Transcriptional regulator
HGHAFENF_01376 1.1e-161 S Putative esterase
HGHAFENF_01377 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HGHAFENF_01378 1.8e-223 lsgC M Glycosyl transferases group 1
HGHAFENF_01379 5.6e-21 S Protein of unknown function (DUF2929)
HGHAFENF_01380 1.7e-48 K Cro/C1-type HTH DNA-binding domain
HGHAFENF_01381 3.7e-69 S response to antibiotic
HGHAFENF_01382 4.2e-44 S zinc-ribbon domain
HGHAFENF_01383 5.7e-20
HGHAFENF_01384 8.7e-154 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HGHAFENF_01385 1.8e-78 uspA T universal stress protein
HGHAFENF_01386 0.0 acm2 3.2.1.17 NU Bacterial SH3 domain
HGHAFENF_01387 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
HGHAFENF_01388 4e-60
HGHAFENF_01389 1.7e-73
HGHAFENF_01390 5e-82 yybC S Protein of unknown function (DUF2798)
HGHAFENF_01391 6.1e-43
HGHAFENF_01392 5.2e-47
HGHAFENF_01393 9.3e-206 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HGHAFENF_01394 2.3e-56 dsbJ 2.7.1.180, 5.3.4.1 CO Thioredoxin
HGHAFENF_01395 8.4e-145 yjfP S Dienelactone hydrolase family
HGHAFENF_01396 1.2e-67
HGHAFENF_01397 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HGHAFENF_01398 1.7e-68 lrp QT PucR C-terminal helix-turn-helix domain
HGHAFENF_01399 8.6e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HGHAFENF_01400 1e-174 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
HGHAFENF_01401 2e-100 srlA G PTS system enzyme II sorbitol-specific factor
HGHAFENF_01402 1.1e-86 gutM K Glucitol operon activator protein (GutM)
HGHAFENF_01403 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
HGHAFENF_01404 1.5e-144 IQ NAD dependent epimerase/dehydratase family
HGHAFENF_01405 2.7e-160 rbsU U ribose uptake protein RbsU
HGHAFENF_01406 7.9e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HGHAFENF_01407 8e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGHAFENF_01408 5.9e-188 rbsR K helix_turn _helix lactose operon repressor
HGHAFENF_01409 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HGHAFENF_01410 2.7e-79 T Universal stress protein family
HGHAFENF_01411 2.2e-99 padR K Virulence activator alpha C-term
HGHAFENF_01412 1.7e-104 padC Q Phenolic acid decarboxylase
HGHAFENF_01413 4.4e-141 tesE Q hydratase
HGHAFENF_01414 2.2e-87 yjaB_1 K Acetyltransferase (GNAT) domain
HGHAFENF_01415 1.2e-157 degV S DegV family
HGHAFENF_01416 2.4e-58 2.6.1.2, 2.6.1.66 K Bacteriophage CI repressor helix-turn-helix domain
HGHAFENF_01417 1.5e-255 pepC 3.4.22.40 E aminopeptidase
HGHAFENF_01419 1.2e-108 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HGHAFENF_01420 1.3e-303
HGHAFENF_01422 1.2e-159 S Bacterial protein of unknown function (DUF916)
HGHAFENF_01423 7.7e-92 S Cell surface protein
HGHAFENF_01424 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HGHAFENF_01425 4.6e-255 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HGHAFENF_01426 2.1e-129 jag S R3H domain protein
HGHAFENF_01427 6e-238 Q Imidazolonepropionase and related amidohydrolases
HGHAFENF_01428 2e-310 E ABC transporter, substratebinding protein
HGHAFENF_01429 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HGHAFENF_01430 6.4e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HGHAFENF_01431 9.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HGHAFENF_01432 2e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HGHAFENF_01433 5e-37 yaaA S S4 domain protein YaaA
HGHAFENF_01434 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HGHAFENF_01435 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HGHAFENF_01436 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HGHAFENF_01437 1.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
HGHAFENF_01438 6.8e-62 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HGHAFENF_01439 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HGHAFENF_01440 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HGHAFENF_01441 1.4e-67 rplI J Binds to the 23S rRNA
HGHAFENF_01442 7.8e-242 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HGHAFENF_01443 8.8e-226 yttB EGP Major facilitator Superfamily
HGHAFENF_01444 3.6e-143 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HGHAFENF_01445 1.1e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HGHAFENF_01447 1.9e-276 E ABC transporter, substratebinding protein
HGHAFENF_01449 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HGHAFENF_01450 2.1e-205 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HGHAFENF_01451 6.3e-197 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
HGHAFENF_01452 8.1e-279 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
HGHAFENF_01453 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HGHAFENF_01454 4e-303 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
HGHAFENF_01456 4.5e-143 S haloacid dehalogenase-like hydrolase
HGHAFENF_01457 1e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HGHAFENF_01458 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
HGHAFENF_01459 1.3e-78 S Pyridoxamine 5'-phosphate oxidase
HGHAFENF_01460 1.6e-31 cspA K Cold shock protein domain
HGHAFENF_01461 1.7e-37
HGHAFENF_01463 6.2e-131 K response regulator
HGHAFENF_01464 0.0 vicK 2.7.13.3 T Histidine kinase
HGHAFENF_01465 2e-244 yycH S YycH protein
HGHAFENF_01466 2.9e-151 yycI S YycH protein
HGHAFENF_01467 8.9e-158 vicX 3.1.26.11 S domain protein
HGHAFENF_01468 6.8e-173 htrA 3.4.21.107 O serine protease
HGHAFENF_01469 1.2e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HGHAFENF_01470 1.5e-95 K Bacterial regulatory proteins, tetR family
HGHAFENF_01471 1.2e-261 calB 1.2.1.68 C Belongs to the aldehyde dehydrogenase family
HGHAFENF_01472 6.8e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
HGHAFENF_01473 9.1e-121 pnb C nitroreductase
HGHAFENF_01474 2.6e-64 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
HGHAFENF_01475 2e-115 S Elongation factor G-binding protein, N-terminal
HGHAFENF_01476 0.0 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
HGHAFENF_01477 1.6e-258 P Sodium:sulfate symporter transmembrane region
HGHAFENF_01478 5.7e-158 K LysR family
HGHAFENF_01479 1e-72 C FMN binding
HGHAFENF_01480 1.1e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HGHAFENF_01481 2.3e-164 ptlF S KR domain
HGHAFENF_01482 6.4e-159 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
HGHAFENF_01483 1.3e-122 drgA C Nitroreductase family
HGHAFENF_01484 1.3e-290 QT PucR C-terminal helix-turn-helix domain
HGHAFENF_01485 5.5e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HGHAFENF_01486 2.9e-57 pva1 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HGHAFENF_01487 3.6e-99 pva1 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HGHAFENF_01488 7.4e-250 yjjP S Putative threonine/serine exporter
HGHAFENF_01489 1.7e-134 wzb 3.1.3.48 T Tyrosine phosphatase family
HGHAFENF_01490 1.4e-254 1.14.14.9 Q 4-hydroxyphenylacetate
HGHAFENF_01491 2.9e-81 6.3.3.2 S ASCH
HGHAFENF_01492 1.4e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
HGHAFENF_01493 5.5e-172 yobV1 K WYL domain
HGHAFENF_01494 1e-116 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HGHAFENF_01495 0.0 tetP J elongation factor G
HGHAFENF_01496 8.2e-39 S Protein of unknown function
HGHAFENF_01497 2.7e-61 S Protein of unknown function
HGHAFENF_01498 3.6e-152 EG EamA-like transporter family
HGHAFENF_01499 3.6e-93 MA20_25245 K FR47-like protein
HGHAFENF_01500 2e-126 hchA S DJ-1/PfpI family
HGHAFENF_01501 5.4e-181 1.1.1.1 C nadph quinone reductase
HGHAFENF_01502 1.9e-47 K helix_turn_helix, Arsenical Resistance Operon Repressor
HGHAFENF_01503 3.9e-235 mepA V MATE efflux family protein
HGHAFENF_01504 1.2e-25 L Phage integrase, N-terminal SAM-like domain
HGHAFENF_01505 2.2e-39 L Pfam:Integrase_AP2
HGHAFENF_01506 1.3e-138 f42a O Band 7 protein
HGHAFENF_01507 1.2e-302 norB EGP Major Facilitator
HGHAFENF_01508 2.6e-92 K transcriptional regulator
HGHAFENF_01509 1.7e-193 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HGHAFENF_01510 4.6e-88 ykhA 3.1.2.20 I Thioesterase superfamily
HGHAFENF_01511 2.7e-160 K LysR substrate binding domain
HGHAFENF_01512 1.3e-123 S Protein of unknown function (DUF554)
HGHAFENF_01513 2.4e-98 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HGHAFENF_01514 1.3e-134 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HGHAFENF_01515 8.8e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HGHAFENF_01516 3.5e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HGHAFENF_01517 4.7e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HGHAFENF_01518 1.2e-70 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HGHAFENF_01519 5.9e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HGHAFENF_01520 2.1e-227 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HGHAFENF_01521 1.2e-126 IQ reductase
HGHAFENF_01522 2e-169 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HGHAFENF_01523 3.8e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HGHAFENF_01524 7.7e-180 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HGHAFENF_01525 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HGHAFENF_01526 3.8e-179 yneE K Transcriptional regulator
HGHAFENF_01527 3e-145 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HGHAFENF_01528 2.3e-57 S Protein of unknown function (DUF1648)
HGHAFENF_01529 3.7e-196 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HGHAFENF_01530 2.9e-215 3.5.1.47 E Peptidase family M20/M25/M40
HGHAFENF_01531 4.4e-217 E glutamate:sodium symporter activity
HGHAFENF_01532 1.6e-67 ybbJ K Acetyltransferase (GNAT) family
HGHAFENF_01533 2.6e-177 1.6.5.5 C Zinc-binding dehydrogenase
HGHAFENF_01534 1.5e-97 entB 3.5.1.19 Q Isochorismatase family
HGHAFENF_01535 3.9e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HGHAFENF_01536 5.1e-226 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HGHAFENF_01537 2.2e-108 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HGHAFENF_01538 2.4e-123 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HGHAFENF_01539 5.9e-167 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HGHAFENF_01540 1.5e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Peptidase C26
HGHAFENF_01541 2.9e-268 trpE 4.1.3.27 EH Anthranilate synthase component I, N terminal region
HGHAFENF_01543 1.8e-271 XK27_00765
HGHAFENF_01544 2.5e-121 ecsA_2 V AAA domain, putative AbiEii toxin, Type IV TA system
HGHAFENF_01545 1.4e-86
HGHAFENF_01546 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
HGHAFENF_01547 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
HGHAFENF_01548 1.4e-50
HGHAFENF_01549 1.9e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HGHAFENF_01550 3.4e-140 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HGHAFENF_01551 8.2e-96 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HGHAFENF_01552 2.6e-39 ylqC S Belongs to the UPF0109 family
HGHAFENF_01553 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HGHAFENF_01554 1.1e-219 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HGHAFENF_01555 2.6e-58 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HGHAFENF_01556 2.5e-169 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HGHAFENF_01557 0.0 smc D Required for chromosome condensation and partitioning
HGHAFENF_01558 5.7e-129 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HGHAFENF_01559 1.7e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HGHAFENF_01560 6.7e-190 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HGHAFENF_01561 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HGHAFENF_01562 0.0 yloV S DAK2 domain fusion protein YloV
HGHAFENF_01563 1.8e-57 asp S Asp23 family, cell envelope-related function
HGHAFENF_01564 4.9e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HGHAFENF_01565 5.8e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
HGHAFENF_01566 1.2e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HGHAFENF_01567 1.6e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HGHAFENF_01568 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HGHAFENF_01569 1.7e-134 stp 3.1.3.16 T phosphatase
HGHAFENF_01570 1.4e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HGHAFENF_01571 4.2e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HGHAFENF_01572 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HGHAFENF_01573 4e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HGHAFENF_01574 2.4e-30 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HGHAFENF_01575 3.3e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HGHAFENF_01576 1.7e-54
HGHAFENF_01577 4.9e-106 opuCD P Binding-protein-dependent transport system inner membrane component
HGHAFENF_01578 6e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HGHAFENF_01579 1.2e-104 opuCB E ABC transporter permease
HGHAFENF_01580 5.7e-222 opuCA 3.6.3.32 E ABC transporter, ATP-binding protein
HGHAFENF_01581 6.3e-307 recN L May be involved in recombinational repair of damaged DNA
HGHAFENF_01582 7.4e-77 argR K Regulates arginine biosynthesis genes
HGHAFENF_01583 4e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HGHAFENF_01584 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HGHAFENF_01585 4.3e-33 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HGHAFENF_01586 1.6e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HGHAFENF_01587 2.2e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HGHAFENF_01588 1.7e-67 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HGHAFENF_01589 3.5e-74 yqhY S Asp23 family, cell envelope-related function
HGHAFENF_01590 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HGHAFENF_01591 1e-193 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HGHAFENF_01592 5.4e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HGHAFENF_01593 3.2e-53 ysxB J Cysteine protease Prp
HGHAFENF_01594 7.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HGHAFENF_01595 5.2e-89 K Transcriptional regulator
HGHAFENF_01596 5.4e-19
HGHAFENF_01600 1.7e-30
HGHAFENF_01601 9.1e-56
HGHAFENF_01602 3.1e-98 dut S Protein conserved in bacteria
HGHAFENF_01603 4e-181
HGHAFENF_01604 2.5e-161
HGHAFENF_01605 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
HGHAFENF_01606 4.6e-64 glnR K Transcriptional regulator
HGHAFENF_01607 2.4e-175 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HGHAFENF_01608 5.8e-140 glpQ 3.1.4.46 C phosphodiesterase
HGHAFENF_01609 6.9e-23 WQ51_02665 S Protein of unknown function (DUF3042)
HGHAFENF_01610 4.4e-68 yqhL P Rhodanese-like protein
HGHAFENF_01611 1.9e-110 pepE 3.4.13.21 E Belongs to the peptidase S51 family
HGHAFENF_01612 5.7e-180 glk 2.7.1.2 G Glucokinase
HGHAFENF_01613 1.4e-33 yqgQ S Bacterial protein of unknown function (DUF910)
HGHAFENF_01614 1e-114 gluP 3.4.21.105 S Peptidase, S54 family
HGHAFENF_01615 2.8e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HGHAFENF_01616 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HGHAFENF_01617 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HGHAFENF_01618 0.0 S membrane
HGHAFENF_01619 1.5e-54 yneR S Belongs to the HesB IscA family
HGHAFENF_01620 4e-75 XK27_02470 K LytTr DNA-binding domain
HGHAFENF_01621 2.3e-96 liaI S membrane
HGHAFENF_01622 1e-51 M domain protein
HGHAFENF_01623 5.7e-23 M domain protein
HGHAFENF_01625 8.4e-17 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HGHAFENF_01626 1.6e-150 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HGHAFENF_01627 0.0 3.6.3.6 P Cation transporter/ATPase, N-terminus
HGHAFENF_01628 6e-12 3.6.3.6 P Cation transporter/ATPase, N-terminus
HGHAFENF_01629 1e-200 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HGHAFENF_01630 1.5e-215 mutS L ATPase domain of DNA mismatch repair MUTS family
HGHAFENF_01631 2.2e-140 mutS L ATPase domain of DNA mismatch repair MUTS family
HGHAFENF_01632 1e-268 mutS L MutS domain V
HGHAFENF_01633 8.9e-184 ykoT GT2 M Glycosyl transferase family 2
HGHAFENF_01634 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HGHAFENF_01635 4.8e-67 S NUDIX domain
HGHAFENF_01636 0.0 S membrane
HGHAFENF_01637 3.7e-172 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HGHAFENF_01638 3e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HGHAFENF_01639 6.9e-223 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HGHAFENF_01640 1.4e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HGHAFENF_01641 9.3e-106 GBS0088 S Nucleotidyltransferase
HGHAFENF_01642 1.4e-106
HGHAFENF_01643 5.1e-116 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HGHAFENF_01644 3.3e-112 K Bacterial regulatory proteins, tetR family
HGHAFENF_01645 3.6e-241 npr 1.11.1.1 C NADH oxidase
HGHAFENF_01646 0.0
HGHAFENF_01647 6.3e-58
HGHAFENF_01648 7.9e-61
HGHAFENF_01649 1.4e-192 S Fn3-like domain
HGHAFENF_01650 4e-103 S WxL domain surface cell wall-binding
HGHAFENF_01651 5.1e-77 S WxL domain surface cell wall-binding
HGHAFENF_01652 3.3e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HGHAFENF_01653 3.5e-39
HGHAFENF_01654 9.9e-82 hit FG histidine triad
HGHAFENF_01655 1.6e-134 ecsA V ABC transporter, ATP-binding protein
HGHAFENF_01656 4.8e-224 ecsB U ABC transporter
HGHAFENF_01657 3.2e-152 ytmP 2.7.1.89 M Choline/ethanolamine kinase
HGHAFENF_01658 3.7e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HGHAFENF_01659 1.6e-54 ytzB S Peptidase propeptide and YPEB domain
HGHAFENF_01660 1.5e-112 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HGHAFENF_01661 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HGHAFENF_01662 9.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HGHAFENF_01663 7.9e-21 S Virus attachment protein p12 family
HGHAFENF_01664 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HGHAFENF_01665 1.3e-34 feoA P FeoA domain
HGHAFENF_01666 4.2e-144 sufC O FeS assembly ATPase SufC
HGHAFENF_01667 2.9e-243 sufD O FeS assembly protein SufD
HGHAFENF_01668 8.9e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HGHAFENF_01669 1.6e-82 nifU C SUF system FeS assembly protein, NifU family
HGHAFENF_01670 1.4e-272 sufB O assembly protein SufB
HGHAFENF_01671 5.5e-45 yitW S Iron-sulfur cluster assembly protein
HGHAFENF_01672 2.3e-111 hipB K Helix-turn-helix
HGHAFENF_01673 1.3e-120 ybhL S Belongs to the BI1 family
HGHAFENF_01674 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HGHAFENF_01675 1.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HGHAFENF_01676 2.3e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HGHAFENF_01677 4.6e-91 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HGHAFENF_01678 2.5e-248 dnaB L replication initiation and membrane attachment
HGHAFENF_01679 2.1e-171 dnaI L Primosomal protein DnaI
HGHAFENF_01680 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HGHAFENF_01681 1.8e-84 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HGHAFENF_01682 1.9e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HGHAFENF_01683 7.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HGHAFENF_01684 9.9e-57
HGHAFENF_01685 9.4e-239 yrvN L AAA C-terminal domain
HGHAFENF_01686 6.4e-122 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HGHAFENF_01687 1.3e-60 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HGHAFENF_01688 1e-62 hxlR K Transcriptional regulator, HxlR family
HGHAFENF_01689 1.5e-135 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
HGHAFENF_01690 1e-248 pgaC GT2 M Glycosyl transferase
HGHAFENF_01691 2.9e-79
HGHAFENF_01692 1.4e-98 yqeG S HAD phosphatase, family IIIA
HGHAFENF_01693 4.5e-216 yqeH S Ribosome biogenesis GTPase YqeH
HGHAFENF_01694 1.1e-50 yhbY J RNA-binding protein
HGHAFENF_01695 1.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HGHAFENF_01696 3.2e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HGHAFENF_01697 2.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HGHAFENF_01698 5.8e-140 yqeM Q Methyltransferase
HGHAFENF_01699 4.9e-218 ylbM S Belongs to the UPF0348 family
HGHAFENF_01700 1.6e-97 yceD S Uncharacterized ACR, COG1399
HGHAFENF_01701 2.2e-89 S Peptidase propeptide and YPEB domain
HGHAFENF_01702 2.3e-146 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HGHAFENF_01703 4.1e-12 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HGHAFENF_01704 3e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HGHAFENF_01705 4.2e-245 rarA L recombination factor protein RarA
HGHAFENF_01706 4.3e-121 K response regulator
HGHAFENF_01707 5.2e-306 arlS 2.7.13.3 T Histidine kinase
HGHAFENF_01708 5.8e-172 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HGHAFENF_01709 0.0 sbcC L Putative exonuclease SbcCD, C subunit
HGHAFENF_01710 4.5e-227 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HGHAFENF_01711 3.9e-99 S SdpI/YhfL protein family
HGHAFENF_01712 1e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HGHAFENF_01713 6.4e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HGHAFENF_01714 7.9e-140 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HGHAFENF_01715 1.3e-93 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HGHAFENF_01716 7.4e-64 yodB K Transcriptional regulator, HxlR family
HGHAFENF_01717 4.9e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HGHAFENF_01718 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HGHAFENF_01719 6.6e-186 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HGHAFENF_01720 2.6e-112 udk 2.7.1.48 F Cytidine monophosphokinase
HGHAFENF_01721 6.8e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HGHAFENF_01723 3e-252 dtpT U amino acid peptide transporter
HGHAFENF_01724 2e-151 yjjH S Calcineurin-like phosphoesterase
HGHAFENF_01728 1.2e-49 5.3.3.19 S Cupin 2, conserved barrel domain protein
HGHAFENF_01729 2.5e-53 S Cupin domain
HGHAFENF_01730 4.6e-165 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
HGHAFENF_01731 4.7e-194 ybiR P Citrate transporter
HGHAFENF_01732 1.6e-151 pnuC H nicotinamide mononucleotide transporter
HGHAFENF_01733 1.7e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HGHAFENF_01734 1e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HGHAFENF_01735 1.6e-123 gntR1 K UbiC transcription regulator-associated domain protein
HGHAFENF_01736 4.6e-137 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HGHAFENF_01737 3.4e-288 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HGHAFENF_01738 4.7e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HGHAFENF_01739 0.0 pacL 3.6.3.8 P P-type ATPase
HGHAFENF_01740 8.9e-72
HGHAFENF_01741 0.0 yhgF K Tex-like protein N-terminal domain protein
HGHAFENF_01742 5.2e-83 ydcK S Belongs to the SprT family
HGHAFENF_01743 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HGHAFENF_01744 1.6e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HGHAFENF_01746 6.4e-156 G Peptidase_C39 like family
HGHAFENF_01747 1.3e-168 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HGHAFENF_01748 3.4e-133 manY G PTS system
HGHAFENF_01749 3.6e-171 manN G system, mannose fructose sorbose family IID component
HGHAFENF_01750 4.7e-64 S Domain of unknown function (DUF956)
HGHAFENF_01751 0.0 levR K Sigma-54 interaction domain
HGHAFENF_01752 8.6e-72 pts10A 2.7.1.191 G PTS system fructose IIA component
HGHAFENF_01753 5.2e-87 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
HGHAFENF_01754 5.4e-178 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HGHAFENF_01755 9.7e-65 accB 2.3.1.12 I Biotin-requiring enzyme
HGHAFENF_01756 3.4e-247 accC2 6.3.4.14, 6.4.1.2 I Biotin carboxylase C-terminal domain
HGHAFENF_01757 9.8e-141 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HGHAFENF_01758 1.8e-136 accA 2.1.3.15, 6.4.1.2 I Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HGHAFENF_01759 4.8e-168 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HGHAFENF_01760 3.3e-167 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HGHAFENF_01761 1.7e-177 EG EamA-like transporter family
HGHAFENF_01762 9.5e-129 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HGHAFENF_01763 1.8e-113 zmp2 O Zinc-dependent metalloprotease
HGHAFENF_01764 7.3e-258 pepC 3.4.22.40 E Peptidase C1-like family
HGHAFENF_01765 3.2e-124 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HGHAFENF_01766 1.2e-51 HA62_12640 S GCN5-related N-acetyl-transferase
HGHAFENF_01767 3.6e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HGHAFENF_01768 1.3e-257 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HGHAFENF_01769 3.7e-205 yacL S domain protein
HGHAFENF_01770 8.9e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HGHAFENF_01771 6.7e-270 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HGHAFENF_01772 3.5e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HGHAFENF_01773 3.3e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HGHAFENF_01774 5.3e-98 yacP S YacP-like NYN domain
HGHAFENF_01775 4.1e-101 sigH K Sigma-70 region 2
HGHAFENF_01776 6.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HGHAFENF_01777 6.8e-29 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HGHAFENF_01778 3.7e-99 nusG K Participates in transcription elongation, termination and antitermination
HGHAFENF_01779 2.6e-158 S Alpha/beta hydrolase of unknown function (DUF915)
HGHAFENF_01780 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HGHAFENF_01781 5.1e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HGHAFENF_01782 4.6e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HGHAFENF_01783 9.9e-56 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HGHAFENF_01784 9.3e-178 F DNA/RNA non-specific endonuclease
HGHAFENF_01785 9e-39 L nuclease
HGHAFENF_01786 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HGHAFENF_01787 4.6e-108 yvdD 3.2.2.10 S Belongs to the LOG family
HGHAFENF_01788 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGHAFENF_01789 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGHAFENF_01790 6.5e-37 nrdH O Glutaredoxin
HGHAFENF_01791 2.2e-108 rsmC 2.1.1.172 J Methyltransferase
HGHAFENF_01792 5.9e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HGHAFENF_01793 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HGHAFENF_01794 5.8e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HGHAFENF_01795 7.4e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HGHAFENF_01796 2.2e-38 yaaL S Protein of unknown function (DUF2508)
HGHAFENF_01797 5.6e-241 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HGHAFENF_01798 1.1e-50 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HGHAFENF_01799 1.1e-40 ulaB_1 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
HGHAFENF_01800 2e-220 ulaA 2.7.1.194 S PTS system sugar-specific permease component
HGHAFENF_01801 2.5e-99 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HGHAFENF_01802 3.3e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HGHAFENF_01803 2.4e-53 yaaQ S Cyclic-di-AMP receptor
HGHAFENF_01804 3.3e-186 holB 2.7.7.7 L DNA polymerase III
HGHAFENF_01805 1e-57 yabA L Involved in initiation control of chromosome replication
HGHAFENF_01806 1.1e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HGHAFENF_01807 1.1e-147 fat 3.1.2.21 I Acyl-ACP thioesterase
HGHAFENF_01808 4e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HGHAFENF_01809 5.5e-211 phnW 2.5.1.49, 2.6.1.37, 3.11.1.1 E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HGHAFENF_01810 3.2e-144 phnX 2.6.1.37, 3.1.3.18, 3.11.1.1 E Belongs to the HAD-like hydrolase superfamily. PhnX family
HGHAFENF_01811 2.5e-43 phnE1 3.6.1.63 U ABC transporter permease
HGHAFENF_01812 1.1e-87 phnE1 3.6.1.63 U ABC transporter permease
HGHAFENF_01813 7.7e-138 phnE 3.6.1.63 U Phosphonate ABC transporter permease
HGHAFENF_01814 9.7e-138 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HGHAFENF_01815 1.9e-189 phnD P Phosphonate ABC transporter
HGHAFENF_01816 5e-128 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HGHAFENF_01817 6.7e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HGHAFENF_01818 1e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HGHAFENF_01819 1.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HGHAFENF_01821 3.9e-226 M Glycosyl transferase family 2
HGHAFENF_01822 7e-117 plnP S CAAX protease self-immunity
HGHAFENF_01823 8.4e-27
HGHAFENF_01824 4.3e-18 plnA
HGHAFENF_01825 1e-235 plnB 2.7.13.3 T GHKL domain
HGHAFENF_01826 9.1e-133 plnC K LytTr DNA-binding domain
HGHAFENF_01827 3.7e-134 plnD K LytTr DNA-binding domain
HGHAFENF_01828 2.2e-129 S CAAX protease self-immunity
HGHAFENF_01829 2.4e-22 plnF
HGHAFENF_01830 6.7e-23
HGHAFENF_01831 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HGHAFENF_01832 5.2e-243 mesE M Transport protein ComB
HGHAFENF_01833 5.5e-95 S CAAX protease self-immunity
HGHAFENF_01834 1.6e-120 ypbD S CAAX protease self-immunity
HGHAFENF_01835 4.7e-112 V CAAX protease self-immunity
HGHAFENF_01836 1e-114 S CAAX protease self-immunity
HGHAFENF_01837 2.6e-29
HGHAFENF_01838 0.0 helD 3.6.4.12 L DNA helicase
HGHAFENF_01839 1.2e-140 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HGHAFENF_01840 2.6e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HGHAFENF_01841 9e-130 K UbiC transcription regulator-associated domain protein
HGHAFENF_01842 1.9e-253 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGHAFENF_01843 3.9e-24
HGHAFENF_01844 2.6e-76 S Domain of unknown function (DUF3284)
HGHAFENF_01845 1.5e-250 chbC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGHAFENF_01846 7.3e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HGHAFENF_01847 1e-162 GK ROK family
HGHAFENF_01848 4.1e-133 K Helix-turn-helix domain, rpiR family
HGHAFENF_01849 2.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HGHAFENF_01850 2.4e-206
HGHAFENF_01851 3.5e-151 S Psort location Cytoplasmic, score
HGHAFENF_01852 8.2e-168 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HGHAFENF_01853 4e-229 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HGHAFENF_01854 3.1e-178
HGHAFENF_01855 8.6e-133 cobB K SIR2 family
HGHAFENF_01856 2e-160 yunF F Protein of unknown function DUF72
HGHAFENF_01857 5.2e-71 mutT 3.6.1.55 F DNA mismatch repair protein MutT
HGHAFENF_01858 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HGHAFENF_01859 1.3e-210 bcr1 EGP Major facilitator Superfamily
HGHAFENF_01860 5.7e-146 tatD L hydrolase, TatD family
HGHAFENF_01861 4.7e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HGHAFENF_01862 8e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HGHAFENF_01863 3.2e-37 veg S Biofilm formation stimulator VEG
HGHAFENF_01864 5.7e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HGHAFENF_01865 1.3e-181 S Prolyl oligopeptidase family
HGHAFENF_01866 9.8e-129 fhuC 3.6.3.35 P ABC transporter
HGHAFENF_01867 9.2e-131 znuB U ABC 3 transport family
HGHAFENF_01868 6.4e-43 ankB S ankyrin repeats
HGHAFENF_01869 2.1e-31
HGHAFENF_01870 6.6e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HGHAFENF_01871 1.2e-207 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HGHAFENF_01872 1.8e-150 bla1 3.5.2.6 V Beta-lactamase enzyme family
HGHAFENF_01873 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HGHAFENF_01874 2.4e-184 S DUF218 domain
HGHAFENF_01875 4.1e-125
HGHAFENF_01876 3.7e-148 yxeH S hydrolase
HGHAFENF_01877 2.6e-263 ywfO S HD domain protein
HGHAFENF_01878 4.8e-154 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HGHAFENF_01879 3.8e-78 ywiB S Domain of unknown function (DUF1934)
HGHAFENF_01880 4e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HGHAFENF_01881 3.4e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HGHAFENF_01882 4.7e-246 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HGHAFENF_01883 3.1e-229 tdcC E amino acid
HGHAFENF_01884 9.8e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HGHAFENF_01885 7.6e-158 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HGHAFENF_01886 1.1e-130 S YheO-like PAS domain
HGHAFENF_01887 5.1e-27
HGHAFENF_01888 3.6e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HGHAFENF_01889 3e-240 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HGHAFENF_01890 7.8e-41 rpmE2 J Ribosomal protein L31
HGHAFENF_01891 2.7e-213 J translation release factor activity
HGHAFENF_01892 9.2e-127 srtA 3.4.22.70 M sortase family
HGHAFENF_01893 1.7e-91 lemA S LemA family
HGHAFENF_01894 2.1e-139 htpX O Belongs to the peptidase M48B family
HGHAFENF_01895 2e-146
HGHAFENF_01896 1.6e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HGHAFENF_01897 6.6e-258 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HGHAFENF_01898 5.4e-214 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
HGHAFENF_01899 0.0 ctpA 3.6.3.54 P P-type ATPase
HGHAFENF_01900 1.7e-44 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HGHAFENF_01901 2.4e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HGHAFENF_01902 0.0 M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HGHAFENF_01903 1.9e-138 K Helix-turn-helix domain
HGHAFENF_01904 8.4e-38 S TfoX C-terminal domain
HGHAFENF_01905 3.5e-228 hpk9 2.7.13.3 T GHKL domain
HGHAFENF_01906 8.4e-263
HGHAFENF_01907 3.8e-75
HGHAFENF_01908 8e-183 S Cell surface protein
HGHAFENF_01909 1.7e-101 S WxL domain surface cell wall-binding
HGHAFENF_01910 1.7e-176 1.6.5.5 C Alcohol dehydrogenase GroES-like domain
HGHAFENF_01911 2.7e-67 S Iron-sulphur cluster biosynthesis
HGHAFENF_01912 6.6e-116 S GyrI-like small molecule binding domain
HGHAFENF_01913 4.3e-189 S Cell surface protein
HGHAFENF_01914 2e-101 S WxL domain surface cell wall-binding
HGHAFENF_01915 1.1e-62
HGHAFENF_01916 1.3e-208 NU Mycoplasma protein of unknown function, DUF285
HGHAFENF_01917 5.9e-117
HGHAFENF_01918 3e-116 S Haloacid dehalogenase-like hydrolase
HGHAFENF_01919 2e-61 K Transcriptional regulator, HxlR family
HGHAFENF_01920 8.4e-213 ytbD EGP Major facilitator Superfamily
HGHAFENF_01921 1.4e-94 M ErfK YbiS YcfS YnhG
HGHAFENF_01922 0.0 asnB 6.3.5.4 E Asparagine synthase
HGHAFENF_01923 1.7e-134 K LytTr DNA-binding domain
HGHAFENF_01924 3e-205 2.7.13.3 T GHKL domain
HGHAFENF_01925 7.9e-100 fadR K Bacterial regulatory proteins, tetR family
HGHAFENF_01926 2.8e-168 GM NmrA-like family
HGHAFENF_01927 4.5e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HGHAFENF_01928 1e-294 M Glycosyl hydrolases family 25
HGHAFENF_01929 5.6e-23 M Glycosyl hydrolases family 25
HGHAFENF_01930 1e-47 S Domain of unknown function (DUF1905)
HGHAFENF_01931 3.7e-63 hxlR K HxlR-like helix-turn-helix
HGHAFENF_01932 9.8e-132 ydfG S KR domain
HGHAFENF_01933 4e-96 K Bacterial regulatory proteins, tetR family
HGHAFENF_01934 1.3e-190 1.1.1.219 GM Male sterility protein
HGHAFENF_01935 4.1e-101 S Protein of unknown function (DUF1211)
HGHAFENF_01936 1.5e-180 S Aldo keto reductase
HGHAFENF_01937 1.6e-253 yfjF U Sugar (and other) transporter
HGHAFENF_01938 7.4e-109 K Bacterial regulatory proteins, tetR family
HGHAFENF_01939 4e-170 fhuD P Periplasmic binding protein
HGHAFENF_01940 1.1e-144 fhuC 3.6.3.34 HP ABC transporter
HGHAFENF_01941 2.1e-177 sirB U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGHAFENF_01942 3.9e-171 fhuG U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGHAFENF_01943 5.4e-92 K Bacterial regulatory proteins, tetR family
HGHAFENF_01944 1.9e-161 GM NmrA-like family
HGHAFENF_01945 2.5e-130 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HGHAFENF_01946 1.3e-68 maa S transferase hexapeptide repeat
HGHAFENF_01947 7.5e-152 IQ Enoyl-(Acyl carrier protein) reductase
HGHAFENF_01948 1.6e-64 K helix_turn_helix, mercury resistance
HGHAFENF_01949 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
HGHAFENF_01950 8.6e-177 S Bacterial protein of unknown function (DUF916)
HGHAFENF_01951 9.6e-90 S WxL domain surface cell wall-binding
HGHAFENF_01952 3.2e-157 NU Mycoplasma protein of unknown function, DUF285
HGHAFENF_01953 3.1e-39 NU Mycoplasma protein of unknown function, DUF285
HGHAFENF_01954 2.1e-117 K Bacterial regulatory proteins, tetR family
HGHAFENF_01955 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HGHAFENF_01956 1.3e-290 yjcE P Sodium proton antiporter
HGHAFENF_01957 1.5e-152 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
HGHAFENF_01958 7.9e-163 K LysR substrate binding domain
HGHAFENF_01959 1.7e-284 1.3.5.4 C FAD binding domain
HGHAFENF_01960 0.0 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S MucBP domain
HGHAFENF_01961 1.7e-84 dps P Belongs to the Dps family
HGHAFENF_01962 1.9e-30
HGHAFENF_01964 6.9e-78 ctsR K Belongs to the CtsR family
HGHAFENF_01965 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HGHAFENF_01966 1.5e-109 K Bacterial regulatory proteins, tetR family
HGHAFENF_01967 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGHAFENF_01968 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGHAFENF_01969 5.6e-113 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HGHAFENF_01970 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HGHAFENF_01971 5.5e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HGHAFENF_01972 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HGHAFENF_01973 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HGHAFENF_01974 4.4e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HGHAFENF_01975 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
HGHAFENF_01976 1.8e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HGHAFENF_01977 8.1e-146 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HGHAFENF_01978 8.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HGHAFENF_01979 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HGHAFENF_01980 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HGHAFENF_01981 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HGHAFENF_01982 1.4e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
HGHAFENF_01983 2.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HGHAFENF_01984 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HGHAFENF_01985 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HGHAFENF_01986 3.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HGHAFENF_01987 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HGHAFENF_01988 3.5e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HGHAFENF_01989 3.3e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HGHAFENF_01990 6.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HGHAFENF_01991 2.2e-24 rpmD J Ribosomal protein L30
HGHAFENF_01992 6.3e-70 rplO J Binds to the 23S rRNA
HGHAFENF_01993 1.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HGHAFENF_01994 6.2e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HGHAFENF_01995 3.9e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HGHAFENF_01996 1.1e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HGHAFENF_01997 3.4e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HGHAFENF_01998 5.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGHAFENF_01999 2.1e-61 rplQ J Ribosomal protein L17
HGHAFENF_02000 1.4e-181 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HGHAFENF_02001 4.9e-94 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
HGHAFENF_02002 1.4e-86 ynhH S NusG domain II
HGHAFENF_02003 0.0 ndh 1.6.99.3 C NADH dehydrogenase
HGHAFENF_02004 3.5e-142 cad S FMN_bind
HGHAFENF_02005 1.5e-208 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HGHAFENF_02006 4.7e-154 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGHAFENF_02007 2.2e-165 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGHAFENF_02008 5e-145 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGHAFENF_02009 3.9e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HGHAFENF_02010 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HGHAFENF_02011 1.9e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HGHAFENF_02012 2.3e-164 degV S Uncharacterised protein, DegV family COG1307
HGHAFENF_02013 1.7e-183 ywhK S Membrane
HGHAFENF_02014 2.5e-203 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HGHAFENF_02015 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HGHAFENF_02016 1.2e-163 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HGHAFENF_02017 4e-184 aroF 2.5.1.54 E DAHP synthetase I family
HGHAFENF_02018 4.9e-196 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HGHAFENF_02019 4.7e-263 P Sodium:sulfate symporter transmembrane region
HGHAFENF_02020 9.1e-53 yitW S Iron-sulfur cluster assembly protein
HGHAFENF_02021 5.4e-115 ttdB 4.2.1.2, 4.2.1.32 C Catalyzes the reversible hydration of fumarate to (S)- malate
HGHAFENF_02022 4.4e-177 ttdA 4.2.1.32 C Fumarate hydratase (Fumerase)
HGHAFENF_02023 2.2e-198 K Helix-turn-helix domain
HGHAFENF_02024 6.8e-153 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HGHAFENF_02025 4.5e-132 mntB 3.6.3.35 P ABC transporter
HGHAFENF_02026 4.8e-141 mtsB U ABC 3 transport family
HGHAFENF_02027 1.2e-174 sitA P Belongs to the bacterial solute-binding protein 9 family
HGHAFENF_02028 3.1e-50
HGHAFENF_02029 6e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HGHAFENF_02030 1.7e-260 citP P Sodium:sulfate symporter transmembrane region
HGHAFENF_02031 2.9e-179 citR K sugar-binding domain protein
HGHAFENF_02032 7.9e-208 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
HGHAFENF_02033 9.7e-189 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HGHAFENF_02034 9e-44 citD C Covalent carrier of the coenzyme of citrate lyase
HGHAFENF_02035 5.5e-164 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HGHAFENF_02036 4.6e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HGHAFENF_02041 5.1e-08
HGHAFENF_02047 1.4e-90 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
HGHAFENF_02048 1.8e-182 P secondary active sulfate transmembrane transporter activity
HGHAFENF_02049 5.8e-94
HGHAFENF_02050 2e-94 K Acetyltransferase (GNAT) domain
HGHAFENF_02051 1.1e-155 T Calcineurin-like phosphoesterase superfamily domain
HGHAFENF_02053 5.2e-232 mntH P H( )-stimulated, divalent metal cation uptake system
HGHAFENF_02054 7.6e-188 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HGHAFENF_02055 1.7e-254 mmuP E amino acid
HGHAFENF_02056 1.7e-168 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HGHAFENF_02057 9.3e-294 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
HGHAFENF_02058 3.1e-122
HGHAFENF_02059 4.1e-212 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HGHAFENF_02060 1.4e-278 bmr3 EGP Major facilitator Superfamily
HGHAFENF_02061 4.5e-139 N Cell shape-determining protein MreB
HGHAFENF_02062 0.0 S Pfam Methyltransferase
HGHAFENF_02063 2.8e-158 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
HGHAFENF_02064 3.6e-99 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
HGHAFENF_02065 1.8e-297 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
HGHAFENF_02066 4.2e-29
HGHAFENF_02067 7.7e-94 ytqB 2.1.1.176 J Putative rRNA methylase
HGHAFENF_02068 8.8e-124 3.6.1.27 I Acid phosphatase homologues
HGHAFENF_02069 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HGHAFENF_02070 3e-301 ytgP S Polysaccharide biosynthesis protein
HGHAFENF_02071 1.8e-136 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HGHAFENF_02072 3.7e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HGHAFENF_02073 1.3e-273 pepV 3.5.1.18 E dipeptidase PepV
HGHAFENF_02074 4.1e-84 uspA T Belongs to the universal stress protein A family
HGHAFENF_02075 5.2e-201 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
HGHAFENF_02076 1.5e-172 ugpA U Binding-protein-dependent transport system inner membrane component
HGHAFENF_02077 1.9e-150 ugpE G ABC transporter permease
HGHAFENF_02078 6.4e-262 ugpB G Bacterial extracellular solute-binding protein
HGHAFENF_02079 3.8e-125 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HGHAFENF_02080 3.8e-119 dck 2.7.1.74 F deoxynucleoside kinase
HGHAFENF_02081 5.5e-41 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HGHAFENF_02082 3.9e-179 XK27_06930 V domain protein
HGHAFENF_02084 1.2e-124 V Transport permease protein
HGHAFENF_02085 2.3e-156 V ABC transporter
HGHAFENF_02086 4e-176 K LytTr DNA-binding domain
HGHAFENF_02087 3.1e-155 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HGHAFENF_02088 1.6e-64 K helix_turn_helix, mercury resistance
HGHAFENF_02089 3.5e-117 GM NAD(P)H-binding
HGHAFENF_02090 9.3e-159 ypaH EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HGHAFENF_02091 2.9e-148 S Sucrose-6F-phosphate phosphohydrolase
HGHAFENF_02092 1.7e-108
HGHAFENF_02093 3.2e-223 pltK 2.7.13.3 T GHKL domain
HGHAFENF_02094 1.6e-137 pltR K LytTr DNA-binding domain
HGHAFENF_02095 4.5e-55
HGHAFENF_02096 2.5e-59
HGHAFENF_02097 6.7e-114 S CAAX protease self-immunity
HGHAFENF_02098 1.6e-85 ohrR K helix_turn_helix multiple antibiotic resistance protein
HGHAFENF_02099 1e-90
HGHAFENF_02100 2.5e-46
HGHAFENF_02101 0.0 uvrA2 L ABC transporter
HGHAFENF_02103 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HGHAFENF_02104 8.1e-123 tcyB E ABC transporter
HGHAFENF_02105 2.3e-126 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HGHAFENF_02106 1.9e-236 EK Aminotransferase, class I
HGHAFENF_02107 2.1e-168 K LysR substrate binding domain
HGHAFENF_02108 5.6e-147 S Alpha/beta hydrolase of unknown function (DUF915)
HGHAFENF_02109 0.0 S Bacterial membrane protein YfhO
HGHAFENF_02110 4.1e-226 nupG F Nucleoside
HGHAFENF_02111 1.7e-128 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HGHAFENF_02112 2.7e-149 noc K Belongs to the ParB family
HGHAFENF_02113 1.8e-136 soj D Sporulation initiation inhibitor
HGHAFENF_02114 4.8e-157 spo0J K Belongs to the ParB family
HGHAFENF_02115 9.8e-31 yyzM S Bacterial protein of unknown function (DUF951)
HGHAFENF_02116 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HGHAFENF_02117 5.2e-125 XK27_01040 S Protein of unknown function (DUF1129)
HGHAFENF_02118 2.3e-212 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HGHAFENF_02119 2.9e-160 prsA 3.1.3.16, 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HGHAFENF_02120 5.5e-124 yoaK S Protein of unknown function (DUF1275)
HGHAFENF_02121 3.2e-124 K response regulator
HGHAFENF_02122 1.3e-213 hpk31 2.7.13.3 T Histidine kinase
HGHAFENF_02123 5.4e-237 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HGHAFENF_02124 1.3e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HGHAFENF_02125 5.1e-131 azlC E branched-chain amino acid
HGHAFENF_02126 2.3e-54 azlD S branched-chain amino acid
HGHAFENF_02127 1e-109 S membrane transporter protein
HGHAFENF_02128 4.8e-55
HGHAFENF_02129 3.9e-75 S Psort location Cytoplasmic, score
HGHAFENF_02130 6e-97 S Domain of unknown function (DUF4352)
HGHAFENF_02131 2.9e-23 S Protein of unknown function (DUF4064)
HGHAFENF_02132 3.2e-200 KLT Protein tyrosine kinase
HGHAFENF_02133 3.9e-162
HGHAFENF_02134 4.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HGHAFENF_02135 2.1e-79
HGHAFENF_02136 9.2e-209 xylR GK ROK family
HGHAFENF_02137 1.9e-171 K AI-2E family transporter
HGHAFENF_02138 7.9e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HGHAFENF_02139 8.8e-40
HGHAFENF_02141 6.8e-33 L transposase activity
HGHAFENF_02143 2.4e-104 K Bacterial regulatory proteins, tetR family
HGHAFENF_02144 9.2e-65 S Domain of unknown function (DUF4440)
HGHAFENF_02145 6.5e-260 qacA EGP Fungal trichothecene efflux pump (TRI12)
HGHAFENF_02146 2.2e-78 3.5.4.1 GM SnoaL-like domain
HGHAFENF_02147 3.3e-109 GM NAD(P)H-binding
HGHAFENF_02148 4.6e-35 S aldo-keto reductase (NADP) activity
HGHAFENF_02149 2.3e-101 akr5f 1.1.1.346 S reductase
HGHAFENF_02150 1.2e-104 M ErfK YbiS YcfS YnhG
HGHAFENF_02151 4.2e-71 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HGHAFENF_02152 8.1e-84 3.2.1.17, 3.5.1.28 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HGHAFENF_02154 5.8e-205 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HGHAFENF_02155 4.2e-95 C Alcohol dehydrogenase GroES-like domain
HGHAFENF_02156 4.7e-41 C Alcohol dehydrogenase GroES-like domain
HGHAFENF_02157 1.5e-42 K HxlR-like helix-turn-helix
HGHAFENF_02158 2.7e-108 ydeA S intracellular protease amidase
HGHAFENF_02159 6.5e-44 S Protein of unknown function (DUF3781)
HGHAFENF_02160 2e-209 S Membrane
HGHAFENF_02161 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HGHAFENF_02162 1.4e-47 ulaB 2.7.1.194, 2.7.1.200 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HGHAFENF_02163 5.8e-234 ulaA 2.7.1.194 S PTS system sugar-specific permease component
HGHAFENF_02164 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HGHAFENF_02165 1.1e-65 S Protein of unknown function (DUF1093)
HGHAFENF_02166 0.0 bglF 2.7.1.193, 2.7.1.211 G phosphotransferase system
HGHAFENF_02167 3.8e-292 arbB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HGHAFENF_02168 7.3e-147 licT2 K CAT RNA binding domain
HGHAFENF_02170 1.2e-25 K sequence-specific DNA binding
HGHAFENF_02172 8.4e-17 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HGHAFENF_02173 8.2e-180 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HGHAFENF_02174 6.4e-257 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HGHAFENF_02175 8.7e-262 frdC 1.3.5.4 C FAD binding domain
HGHAFENF_02176 3.6e-94 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HGHAFENF_02177 4.9e-162 mleR K LysR family transcriptional regulator
HGHAFENF_02178 1.8e-167 mleR K LysR family
HGHAFENF_02179 1.6e-307 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HGHAFENF_02180 1.4e-165 mleP S Sodium Bile acid symporter family
HGHAFENF_02181 5.8e-253 yfnA E Amino Acid
HGHAFENF_02182 3e-99 S ECF transporter, substrate-specific component
HGHAFENF_02183 3.4e-22
HGHAFENF_02184 2.1e-296 S Alpha beta
HGHAFENF_02185 5.4e-275 cydA 1.10.3.14 C ubiquinol oxidase
HGHAFENF_02186 2.6e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HGHAFENF_02187 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HGHAFENF_02188 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HGHAFENF_02189 6.9e-157 ddpX 3.4.13.22 S L,D-transpeptidase catalytic domain
HGHAFENF_02190 2.3e-182 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HGHAFENF_02191 2.5e-164 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HGHAFENF_02192 8.7e-184 S Oxidoreductase family, NAD-binding Rossmann fold
HGHAFENF_02193 3.1e-113 acmA 3.2.1.17 NU mannosyl-glycoprotein
HGHAFENF_02194 9.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HGHAFENF_02195 1.5e-92 S UPF0316 protein
HGHAFENF_02196 1.3e-218 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HGHAFENF_02197 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HGHAFENF_02198 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HGHAFENF_02199 7.5e-198 camS S sex pheromone
HGHAFENF_02200 3.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HGHAFENF_02201 2.1e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HGHAFENF_02202 7.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HGHAFENF_02203 1e-190 yegS 2.7.1.107 G Lipid kinase
HGHAFENF_02204 5.2e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HGHAFENF_02205 2.1e-100 yobS K Bacterial regulatory proteins, tetR family
HGHAFENF_02206 0.0 yfgQ P E1-E2 ATPase
HGHAFENF_02207 1.2e-239 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGHAFENF_02208 5.1e-167 S Alpha/beta hydrolase of unknown function (DUF915)
HGHAFENF_02209 2.3e-151 gntR K rpiR family
HGHAFENF_02210 1.1e-144 lys M Glycosyl hydrolases family 25
HGHAFENF_02211 1.1e-62 S Domain of unknown function (DUF4828)
HGHAFENF_02212 2.7e-31 cspA K 'Cold-shock' DNA-binding domain
HGHAFENF_02213 4.2e-189 mocA S Oxidoreductase
HGHAFENF_02214 2.6e-239 yfmL 3.6.4.13 L DEAD DEAH box helicase
HGHAFENF_02216 2.3e-75 T Universal stress protein family
HGHAFENF_02217 1.9e-92 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGHAFENF_02218 1.9e-138 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGHAFENF_02219 1.8e-164 S Alpha/beta hydrolase of unknown function (DUF915)
HGHAFENF_02221 1.3e-73
HGHAFENF_02222 5e-107
HGHAFENF_02223 4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HGHAFENF_02224 1.2e-219 pbpX1 V Beta-lactamase
HGHAFENF_02225 4.4e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HGHAFENF_02226 3.3e-156 yihY S Belongs to the UPF0761 family
HGHAFENF_02227 9.7e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HGHAFENF_02230 2.1e-222 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HGHAFENF_02231 2.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HGHAFENF_02232 1.2e-113 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HGHAFENF_02233 1.5e-264 lysP E amino acid
HGHAFENF_02234 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HGHAFENF_02235 4.2e-92 K Transcriptional regulator
HGHAFENF_02236 2.8e-99 2.3.1.128 J Acetyltransferase (GNAT) domain
HGHAFENF_02237 2e-154 I alpha/beta hydrolase fold
HGHAFENF_02238 2.3e-119 lssY 3.6.1.27 I phosphatase
HGHAFENF_02239 1.5e-189 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HGHAFENF_02240 2.2e-76 S Threonine/Serine exporter, ThrE
HGHAFENF_02241 1.5e-130 thrE S Putative threonine/serine exporter
HGHAFENF_02242 6e-31 cspC K Cold shock protein
HGHAFENF_02243 2e-120 sirR K iron dependent repressor
HGHAFENF_02244 2.6e-58
HGHAFENF_02245 1.7e-84 merR K MerR HTH family regulatory protein
HGHAFENF_02246 7e-270 lmrB EGP Major facilitator Superfamily
HGHAFENF_02247 1.4e-117 S Domain of unknown function (DUF4811)
HGHAFENF_02248 2.7e-104
HGHAFENF_02249 4.4e-35 yyaN K MerR HTH family regulatory protein
HGHAFENF_02250 1.3e-120 azlC E branched-chain amino acid
HGHAFENF_02251 7.2e-50 azlD S Branched-chain amino acid transport protein (AzlD)
HGHAFENF_02252 0.0 asnB 6.3.5.4 E Asparagine synthase
HGHAFENF_02253 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
HGHAFENF_02254 5.2e-281 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HGHAFENF_02255 6.1e-255 xylP2 G symporter
HGHAFENF_02256 9e-192 nlhH_1 I alpha/beta hydrolase fold
HGHAFENF_02257 5.6e-49
HGHAFENF_02258 5e-122 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HGHAFENF_02259 7e-101 3.2.2.20 K FR47-like protein
HGHAFENF_02260 1.3e-126 yibF S overlaps another CDS with the same product name
HGHAFENF_02261 3.7e-219 yibE S overlaps another CDS with the same product name
HGHAFENF_02262 2.3e-179
HGHAFENF_02263 5.6e-138 S NADPH-dependent FMN reductase
HGHAFENF_02264 1.5e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
HGHAFENF_02265 1.4e-161 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HGHAFENF_02266 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HGHAFENF_02267 4.1e-32 L leucine-zipper of insertion element IS481
HGHAFENF_02268 1e-41
HGHAFENF_02269 3.9e-221 2.7.7.7, 3.6.4.12 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HGHAFENF_02270 6.7e-278 pipD E Dipeptidase
HGHAFENF_02271 9.9e-199 asnA 6.3.1.1 F aspartate--ammonia ligase
HGHAFENF_02272 2.8e-254 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HGHAFENF_02273 4.2e-115 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HGHAFENF_02274 2.3e-81 rmaD K Transcriptional regulator
HGHAFENF_02276 0.0 1.3.5.4 C FMN_bind
HGHAFENF_02277 9.5e-172 K Transcriptional regulator
HGHAFENF_02278 7.8e-97 K Helix-turn-helix domain
HGHAFENF_02279 2.9e-139 K sequence-specific DNA binding
HGHAFENF_02280 8e-73 S AAA domain
HGHAFENF_02282 0.0 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
HGHAFENF_02283 3e-90 XK27_09665 5.4.2.11 G Phosphoglycerate mutase family
HGHAFENF_02284 2.6e-44 S MazG-like family
HGHAFENF_02285 0.0 N Uncharacterized conserved protein (DUF2075)
HGHAFENF_02286 0.0 pepN 3.4.11.2 E aminopeptidase
HGHAFENF_02287 4.1e-101 G Glycogen debranching enzyme
HGHAFENF_02288 3.4e-47 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HGHAFENF_02289 1e-155 yjdB S Domain of unknown function (DUF4767)
HGHAFENF_02290 7e-40
HGHAFENF_02292 8.6e-249 EGP Major facilitator Superfamily
HGHAFENF_02293 2e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
HGHAFENF_02294 4.7e-83 cvpA S Colicin V production protein
HGHAFENF_02295 2.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HGHAFENF_02296 2.8e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HGHAFENF_02297 2.6e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
HGHAFENF_02298 4.8e-249 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HGHAFENF_02299 1.7e-105 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
HGHAFENF_02300 1.2e-213 folP 2.5.1.15 H dihydropteroate synthase
HGHAFENF_02301 6.5e-96 tag 3.2.2.20 L glycosylase
HGHAFENF_02303 2.1e-21
HGHAFENF_02305 2.7e-103 K Helix-turn-helix XRE-family like proteins
HGHAFENF_02306 2.7e-160 czcD P cation diffusion facilitator family transporter
HGHAFENF_02307 5.1e-54 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
HGHAFENF_02308 3e-116 hly S protein, hemolysin III
HGHAFENF_02309 1.1e-44 qacH U Small Multidrug Resistance protein
HGHAFENF_02310 4.4e-59 qacC P Small Multidrug Resistance protein
HGHAFENF_02311 4e-217 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
HGHAFENF_02312 3.1e-179 K AI-2E family transporter
HGHAFENF_02313 4.6e-166 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HGHAFENF_02314 0.0 kup P Transport of potassium into the cell
HGHAFENF_02316 1.5e-256 yhdG E C-terminus of AA_permease
HGHAFENF_02317 6.2e-82
HGHAFENF_02319 1.8e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HGHAFENF_02320 1.7e-145 ptp2 3.1.3.48 T Tyrosine phosphatase family
HGHAFENF_02321 3.5e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HGHAFENF_02322 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HGHAFENF_02323 7.4e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HGHAFENF_02324 3.4e-55 S Enterocin A Immunity
HGHAFENF_02325 8.1e-257 gor 1.8.1.7 C Glutathione reductase
HGHAFENF_02326 1.2e-197 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HGHAFENF_02327 1.7e-184 D Alpha beta
HGHAFENF_02328 7.4e-166 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
HGHAFENF_02329 1.1e-294 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 Q Flavin containing amine oxidoreductase
HGHAFENF_02330 3.5e-118 yugP S Putative neutral zinc metallopeptidase
HGHAFENF_02331 4.1e-25
HGHAFENF_02332 2.5e-145 DegV S EDD domain protein, DegV family
HGHAFENF_02333 7.3e-127 lrgB M LrgB-like family
HGHAFENF_02334 5.1e-64 lrgA S LrgA family
HGHAFENF_02335 2.5e-103 J Acetyltransferase (GNAT) domain
HGHAFENF_02336 1.8e-169 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
HGHAFENF_02337 5.4e-36 S Phospholipase_D-nuclease N-terminal
HGHAFENF_02338 7.1e-59 S Enterocin A Immunity
HGHAFENF_02339 9.8e-88 perR P Belongs to the Fur family
HGHAFENF_02340 4.2e-104
HGHAFENF_02341 7.9e-238 S module of peptide synthetase
HGHAFENF_02342 2e-100 S NADPH-dependent FMN reductase
HGHAFENF_02343 1.4e-08
HGHAFENF_02344 3.9e-127 magIII L Base excision DNA repair protein, HhH-GPD family
HGHAFENF_02345 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
HGHAFENF_02346 1.4e-156 1.6.5.2 GM NmrA-like family
HGHAFENF_02347 2e-77 merR K MerR family regulatory protein
HGHAFENF_02348 2.2e-90 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HGHAFENF_02349 2.9e-20 fryA 2.7.1.202 G COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HGHAFENF_02350 2.4e-26 mngA 2.7.1.195, 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
HGHAFENF_02351 2.8e-122 mngA 2.7.1.195, 2.7.1.202 U Phosphotransferase system, EIIC
HGHAFENF_02352 1.5e-307 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
HGHAFENF_02353 5.3e-92 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HGHAFENF_02354 1.4e-147 cof S haloacid dehalogenase-like hydrolase
HGHAFENF_02355 3.4e-152 qorB 1.6.5.2 GM NmrA-like family
HGHAFENF_02361 5.5e-08
HGHAFENF_02371 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HGHAFENF_02372 2.2e-139 yhfI S Metallo-beta-lactamase superfamily
HGHAFENF_02373 7.9e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HGHAFENF_02374 2.2e-131 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HGHAFENF_02375 8.4e-204 coiA 3.6.4.12 S Competence protein
HGHAFENF_02376 0.0 pepF E oligoendopeptidase F
HGHAFENF_02377 3.6e-114 yjbH Q Thioredoxin
HGHAFENF_02378 2.7e-120 yjbM 2.7.6.5 S RelA SpoT domain protein
HGHAFENF_02379 4.7e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HGHAFENF_02380 8.9e-175 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HGHAFENF_02381 5.1e-116 cutC P Participates in the control of copper homeostasis
HGHAFENF_02382 1.3e-193 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HGHAFENF_02383 2.5e-56 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HGHAFENF_02384 4.3e-206 XK27_05220 S AI-2E family transporter
HGHAFENF_02385 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HGHAFENF_02386 1.1e-161 rrmA 2.1.1.187 H Methyltransferase
HGHAFENF_02388 3.7e-209 brnQ U Component of the transport system for branched-chain amino acids
HGHAFENF_02389 1.8e-113 ywnB S NAD(P)H-binding
HGHAFENF_02390 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HGHAFENF_02391 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HGHAFENF_02392 4.2e-175 corA P CorA-like Mg2+ transporter protein
HGHAFENF_02393 1.9e-62 S Protein of unknown function (DUF3397)
HGHAFENF_02394 1.9e-77 mraZ K Belongs to the MraZ family
HGHAFENF_02395 2.9e-176 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HGHAFENF_02396 7.5e-54 ftsL D Cell division protein FtsL
HGHAFENF_02397 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HGHAFENF_02398 8.3e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HGHAFENF_02399 2.1e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HGHAFENF_02400 1.5e-197 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HGHAFENF_02401 5.8e-163 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HGHAFENF_02402 5.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HGHAFENF_02403 1.4e-229 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HGHAFENF_02404 3.3e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HGHAFENF_02405 1.2e-36 yggT S YGGT family
HGHAFENF_02406 3.4e-146 ylmH S S4 domain protein
HGHAFENF_02407 1.2e-86 divIVA D DivIVA domain protein
HGHAFENF_02408 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HGHAFENF_02409 1.1e-189 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HGHAFENF_02410 1.9e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HGHAFENF_02411 4.6e-28
HGHAFENF_02412 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HGHAFENF_02413 7.1e-217 iscS 2.8.1.7 E Aminotransferase class V
HGHAFENF_02414 4.9e-57 XK27_04120 S Putative amino acid metabolism
HGHAFENF_02415 9e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HGHAFENF_02416 1.3e-241 ktrB P Potassium uptake protein
HGHAFENF_02417 4.5e-115 ktrA P domain protein
HGHAFENF_02418 5.1e-120 N WxL domain surface cell wall-binding
HGHAFENF_02419 1.7e-193 S Bacterial protein of unknown function (DUF916)
HGHAFENF_02420 3.2e-267 N domain, Protein
HGHAFENF_02421 5.5e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HGHAFENF_02422 1.6e-120 S Repeat protein
HGHAFENF_02423 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HGHAFENF_02424 1.2e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HGHAFENF_02425 1.5e-22 M domain protein
HGHAFENF_02426 8.4e-60 M domain protein
HGHAFENF_02427 3.5e-76 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
HGHAFENF_02428 1.2e-97
HGHAFENF_02429 0.0 1.3.5.4 C FAD binding domain
HGHAFENF_02430 2.1e-111 1.3.5.4 S NADPH-dependent FMN reductase
HGHAFENF_02431 1.2e-177 K LysR substrate binding domain
HGHAFENF_02432 1.5e-180 3.4.21.102 M Peptidase family S41
HGHAFENF_02433 8.7e-215
HGHAFENF_02434 2.9e-187 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
HGHAFENF_02435 0.0 L AAA domain
HGHAFENF_02436 2.6e-230 yhaO L Ser Thr phosphatase family protein
HGHAFENF_02437 1e-54 yheA S Belongs to the UPF0342 family
HGHAFENF_02438 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HGHAFENF_02439 2.9e-12
HGHAFENF_02440 4.4e-77 argR K Regulates arginine biosynthesis genes
HGHAFENF_02441 1.9e-214 arcT 2.6.1.1 E Aminotransferase
HGHAFENF_02442 4e-102 argO S LysE type translocator
HGHAFENF_02443 8.4e-284 ydfD K Alanine-glyoxylate amino-transferase
HGHAFENF_02444 4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGHAFENF_02445 2.7e-114 M ErfK YbiS YcfS YnhG
HGHAFENF_02446 3.1e-56 EGP Major facilitator Superfamily
HGHAFENF_02447 4.4e-147 EGP Major facilitator Superfamily
HGHAFENF_02448 6.1e-290 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HGHAFENF_02449 6.1e-220 pts15C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGHAFENF_02450 1.1e-47 pts15B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HGHAFENF_02451 1.4e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HGHAFENF_02452 2.4e-62 S Domain of unknown function (DUF3284)
HGHAFENF_02453 0.0 K PRD domain
HGHAFENF_02454 7.6e-107
HGHAFENF_02455 0.0 yhcA V MacB-like periplasmic core domain
HGHAFENF_02456 6.7e-81
HGHAFENF_02457 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HGHAFENF_02458 1.7e-78 elaA S Acetyltransferase (GNAT) domain
HGHAFENF_02461 1.9e-31
HGHAFENF_02462 2.1e-244 dinF V MatE
HGHAFENF_02463 0.0 yfbS P Sodium:sulfate symporter transmembrane region
HGHAFENF_02464 1.8e-304 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
HGHAFENF_02465 3.7e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain
HGHAFENF_02466 8.7e-113 cysC 2.7.1.25, 2.7.7.4 F Catalyzes the synthesis of activated sulfate
HGHAFENF_02467 9.7e-230 sat 2.7.7.4 H the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HGHAFENF_02468 6.1e-307 S Protein conserved in bacteria
HGHAFENF_02469 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HGHAFENF_02470 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HGHAFENF_02471 3.6e-58 S Protein of unknown function (DUF1516)
HGHAFENF_02472 1.9e-89 gtcA S Teichoic acid glycosylation protein
HGHAFENF_02473 2.1e-180
HGHAFENF_02474 7.8e-10
HGHAFENF_02475 1.1e-53
HGHAFENF_02477 3.7e-140 P Major Facilitator Superfamily
HGHAFENF_02478 1.2e-46 K helix_turn_helix, Arsenical Resistance Operon Repressor
HGHAFENF_02479 1.8e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HGHAFENF_02481 3.2e-56 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HGHAFENF_02482 8.3e-110 ypsA S Belongs to the UPF0398 family
HGHAFENF_02483 7.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HGHAFENF_02484 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HGHAFENF_02485 7.4e-180 phnT 3.6.3.30 P ATPases associated with a variety of cellular activities
HGHAFENF_02486 4.5e-183 ftpB P Bacterial extracellular solute-binding protein
HGHAFENF_02487 2.2e-124 ftpA P Binding-protein-dependent transport system inner membrane component
HGHAFENF_02488 3.3e-113 ftpA P Binding-protein-dependent transport system inner membrane component
HGHAFENF_02489 2e-83 uspA T Universal stress protein family
HGHAFENF_02490 5.5e-158 metQ_4 P Belongs to the nlpA lipoprotein family
HGHAFENF_02491 1.7e-98 metI P ABC transporter permease
HGHAFENF_02492 2.4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HGHAFENF_02493 1.3e-128 dnaD L Replication initiation and membrane attachment
HGHAFENF_02494 5.4e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HGHAFENF_02495 1.1e-225 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HGHAFENF_02496 2.1e-72 ypmB S protein conserved in bacteria
HGHAFENF_02497 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HGHAFENF_02498 4e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HGHAFENF_02499 7.4e-175 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HGHAFENF_02500 7.6e-205 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HGHAFENF_02501 2.1e-196 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HGHAFENF_02502 6.2e-193 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HGHAFENF_02503 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HGHAFENF_02504 2.5e-250 malT G Major Facilitator
HGHAFENF_02505 6.1e-88 S Domain of unknown function (DUF4767)
HGHAFENF_02506 5.5e-269 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HGHAFENF_02507 1.2e-149 yitU 3.1.3.104 S hydrolase
HGHAFENF_02508 1.4e-265 yfnA E Amino Acid
HGHAFENF_02509 8.7e-259 gabT 2.6.1.19, 5.1.1.21 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HGHAFENF_02510 1.3e-42
HGHAFENF_02511 3.9e-50
HGHAFENF_02512 1.4e-136 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 U Ion channel
HGHAFENF_02513 5.1e-170 2.5.1.74 H UbiA prenyltransferase family
HGHAFENF_02514 5.7e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HGHAFENF_02515 5.1e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HGHAFENF_02516 8.6e-281 pipD E Dipeptidase
HGHAFENF_02517 9.4e-40
HGHAFENF_02518 4.8e-29 S CsbD-like
HGHAFENF_02519 6.5e-41 S transglycosylase associated protein
HGHAFENF_02520 3.1e-14
HGHAFENF_02521 3.5e-36
HGHAFENF_02522 1.8e-164 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
HGHAFENF_02523 8e-66 S Protein of unknown function (DUF805)
HGHAFENF_02524 1.4e-75 uspA T Belongs to the universal stress protein A family
HGHAFENF_02525 4.3e-67 tspO T TspO/MBR family
HGHAFENF_02526 7.9e-41
HGHAFENF_02527 5.8e-48 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
HGHAFENF_02528 4.5e-114 1.14.99.53 AA10 S Lytic polysaccharide mono-oxygenase, cellulose-degrading
HGHAFENF_02529 2.5e-209 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HGHAFENF_02530 1.6e-28
HGHAFENF_02531 1.1e-53
HGHAFENF_02533 4e-09
HGHAFENF_02534 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HGHAFENF_02535 1.1e-34 ykuJ S Protein of unknown function (DUF1797)
HGHAFENF_02536 1.8e-228 patA 2.6.1.1 E Aminotransferase
HGHAFENF_02537 1.2e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HGHAFENF_02538 7.4e-189 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HGHAFENF_02539 6.9e-200 cpoA GT4 M Glycosyltransferase, group 1 family protein
HGHAFENF_02540 1.4e-223 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HGHAFENF_02541 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HGHAFENF_02542 2.7e-39 ptsH G phosphocarrier protein HPR
HGHAFENF_02543 6.5e-30
HGHAFENF_02544 0.0 clpE O Belongs to the ClpA ClpB family
HGHAFENF_02545 6.2e-102 L Integrase
HGHAFENF_02546 1e-63 K Winged helix DNA-binding domain
HGHAFENF_02547 1.8e-181 oppF P Belongs to the ABC transporter superfamily
HGHAFENF_02548 9.2e-203 oppD P Belongs to the ABC transporter superfamily
HGHAFENF_02549 1.1e-189 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGHAFENF_02550 2.3e-165 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGHAFENF_02551 1.3e-309 oppA E ABC transporter, substratebinding protein
HGHAFENF_02552 3.2e-57 ywjH S Protein of unknown function (DUF1634)
HGHAFENF_02553 5.5e-126 yxaA S membrane transporter protein
HGHAFENF_02554 7.1e-161 lysR5 K LysR substrate binding domain
HGHAFENF_02555 6.5e-198 M MucBP domain
HGHAFENF_02556 1.7e-273
HGHAFENF_02557 6.9e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HGHAFENF_02558 3.4e-255 gor 1.8.1.7 C Glutathione reductase
HGHAFENF_02559 1.1e-169 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
HGHAFENF_02560 4.6e-293 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HGHAFENF_02561 9.5e-213 gntP EG Gluconate
HGHAFENF_02562 3.7e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HGHAFENF_02563 9.3e-188 yueF S AI-2E family transporter
HGHAFENF_02564 9.8e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HGHAFENF_02565 1.3e-17 pbpX V Beta-lactamase
HGHAFENF_02566 5e-138 pbpX V Beta-lactamase
HGHAFENF_02567 1.3e-27 S Antitoxin component of a toxin-antitoxin (TA) module
HGHAFENF_02568 7.8e-48 K sequence-specific DNA binding
HGHAFENF_02569 1.5e-133 cwlO M NlpC/P60 family
HGHAFENF_02570 4.1e-106 ygaC J Belongs to the UPF0374 family
HGHAFENF_02571 2.2e-140 recX 2.4.1.337 GT4 S Regulatory protein RecX
HGHAFENF_02572 1e-125
HGHAFENF_02573 3e-101 K DNA-templated transcription, initiation
HGHAFENF_02574 1e-27
HGHAFENF_02575 7e-30
HGHAFENF_02576 7.3e-33 S Protein of unknown function (DUF2922)
HGHAFENF_02577 3.8e-53
HGHAFENF_02578 3.2e-121 rfbP M Bacterial sugar transferase
HGHAFENF_02579 2.8e-79 3.2.1.96 G Glycosyl hydrolase family 85
HGHAFENF_02580 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HGHAFENF_02581 4e-209 msmK P Belongs to the ABC transporter superfamily
HGHAFENF_02582 9.1e-261 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
HGHAFENF_02583 1.8e-150 malA S maltodextrose utilization protein MalA
HGHAFENF_02584 1.4e-161 malD P ABC transporter permease
HGHAFENF_02585 2.2e-227 malC P Binding-protein-dependent transport system inner membrane component
HGHAFENF_02586 2.1e-230 mdxE G Bacterial extracellular solute-binding protein
HGHAFENF_02587 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
HGHAFENF_02588 2e-180 yvdE K helix_turn _helix lactose operon repressor
HGHAFENF_02589 1e-190 malR K Transcriptional regulator, LacI family
HGHAFENF_02590 1.9e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HGHAFENF_02591 9e-57 dhaM 2.7.1.121 S PTS system fructose IIA component
HGHAFENF_02592 1.9e-101 dhaL 2.7.1.121 S Dak2
HGHAFENF_02593 5e-187 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HGHAFENF_02594 2.2e-190 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HGHAFENF_02595 1.1e-92 K Bacterial regulatory proteins, tetR family
HGHAFENF_02597 8.6e-74 folT 2.7.13.3 T ECF transporter, substrate-specific component
HGHAFENF_02598 4.7e-277 C Electron transfer flavoprotein FAD-binding domain
HGHAFENF_02599 1.6e-117 K Transcriptional regulator
HGHAFENF_02600 1.6e-299 M Exporter of polyketide antibiotics
HGHAFENF_02601 2.3e-170 yjjC V ABC transporter
HGHAFENF_02602 5.5e-144 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HGHAFENF_02603 9.1e-89
HGHAFENF_02604 7.6e-149
HGHAFENF_02605 4.6e-143
HGHAFENF_02606 8.3e-54 K Transcriptional regulator PadR-like family
HGHAFENF_02607 1.6e-129 K UbiC transcription regulator-associated domain protein
HGHAFENF_02608 2.5e-98 S UPF0397 protein
HGHAFENF_02609 0.0 ykoD P ABC transporter, ATP-binding protein
HGHAFENF_02610 6.4e-151 cbiQ P cobalt transport
HGHAFENF_02611 4e-209 C Oxidoreductase
HGHAFENF_02612 2.2e-258
HGHAFENF_02613 5e-52
HGHAFENF_02614 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
HGHAFENF_02615 1.3e-81 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
HGHAFENF_02616 3.6e-165 1.1.1.65 C Aldo keto reductase
HGHAFENF_02617 2.9e-159 S reductase
HGHAFENF_02619 8.1e-216 yeaN P Transporter, major facilitator family protein
HGHAFENF_02620 5e-51 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
HGHAFENF_02621 4.7e-227 mdtG EGP Major facilitator Superfamily
HGHAFENF_02622 1.1e-80 S Protein of unknown function (DUF3021)
HGHAFENF_02623 4.6e-73 hsp1 O Belongs to the small heat shock protein (HSP20) family
HGHAFENF_02624 1.9e-75 papX3 K Transcriptional regulator
HGHAFENF_02625 3e-110 S NADPH-dependent FMN reductase
HGHAFENF_02626 1.6e-28 KT PspC domain
HGHAFENF_02627 1.3e-223 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
HGHAFENF_02628 3.9e-66 lysM M LysM domain
HGHAFENF_02629 2.8e-266 yjeM E Amino Acid
HGHAFENF_02630 1.5e-144 K Helix-turn-helix XRE-family like proteins
HGHAFENF_02631 1.4e-69
HGHAFENF_02633 5e-162 IQ KR domain
HGHAFENF_02634 3.7e-229 amd 3.5.1.47 E Peptidase family M20/M25/M40
HGHAFENF_02635 9.1e-177 O protein import
HGHAFENF_02636 4.8e-311 XK27_09600 V ABC transporter, ATP-binding protein
HGHAFENF_02637 0.0 V ABC transporter
HGHAFENF_02638 8.6e-218 ykiI
HGHAFENF_02639 3.6e-117 GM NAD(P)H-binding
HGHAFENF_02640 1.7e-54 IQ reductase
HGHAFENF_02641 2.7e-67 IQ reductase
HGHAFENF_02642 3.7e-60 I sulfurtransferase activity
HGHAFENF_02643 2.7e-78 yphH S Cupin domain
HGHAFENF_02644 4.7e-93 S Phosphatidylethanolamine-binding protein
HGHAFENF_02645 1.6e-117 GM NAD(P)H-binding
HGHAFENF_02646 2.1e-175 C C4-dicarboxylate transmembrane transporter activity
HGHAFENF_02647 3.8e-131 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HGHAFENF_02648 7.8e-70
HGHAFENF_02649 1.2e-166 K Bacterial regulatory helix-turn-helix protein, lysR family
HGHAFENF_02650 2e-283 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
HGHAFENF_02651 1.2e-73 S Psort location Cytoplasmic, score
HGHAFENF_02652 3.3e-219 T diguanylate cyclase
HGHAFENF_02653 2.6e-120 tag 3.2.2.20 L Methyladenine glycosylase
HGHAFENF_02654 9.4e-92
HGHAFENF_02655 9.1e-164 psaA P Belongs to the bacterial solute-binding protein 9 family
HGHAFENF_02656 1.8e-54 nudA S ASCH
HGHAFENF_02657 4e-107 S SdpI/YhfL protein family
HGHAFENF_02658 6.3e-93 M Lysin motif
HGHAFENF_02659 2.3e-65 M LysM domain
HGHAFENF_02660 5.1e-75 K helix_turn_helix, mercury resistance
HGHAFENF_02661 1.7e-185 1.1.1.219 GM Male sterility protein
HGHAFENF_02662 2e-279 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HGHAFENF_02663 3.3e-267 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGHAFENF_02664 7e-53 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HGHAFENF_02665 8.8e-75 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HGHAFENF_02666 5.3e-150 dicA K Helix-turn-helix domain
HGHAFENF_02667 3.2e-55
HGHAFENF_02668 3.4e-160 T Calcineurin-like phosphoesterase superfamily domain
HGHAFENF_02669 7.4e-64
HGHAFENF_02670 0.0 P Concanavalin A-like lectin/glucanases superfamily
HGHAFENF_02671 0.0 yhcA V ABC transporter, ATP-binding protein
HGHAFENF_02672 1.6e-18
HGHAFENF_02673 4.3e-40 yrkD S Metal-sensitive transcriptional repressor
HGHAFENF_02674 1.5e-55 txlA O Thioredoxin-like domain
HGHAFENF_02675 9.8e-143 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HGHAFENF_02676 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
HGHAFENF_02677 6.9e-181 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
HGHAFENF_02678 7e-127 ydcF S Gram-negative-bacterium-type cell wall biogenesis
HGHAFENF_02679 1.7e-136 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HGHAFENF_02680 7.2e-183 yfeX P Peroxidase
HGHAFENF_02681 6.7e-99 K transcriptional regulator
HGHAFENF_02682 2.6e-159 4.1.1.46 S Amidohydrolase
HGHAFENF_02683 2.5e-52 S Uncharacterized protein conserved in bacteria (DUF2316)
HGHAFENF_02684 8.1e-108
HGHAFENF_02686 2.1e-61
HGHAFENF_02687 3.2e-53
HGHAFENF_02688 1.5e-75 mltD CBM50 M PFAM NLP P60 protein
HGHAFENF_02689 4.8e-284 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
HGHAFENF_02690 1.8e-27
HGHAFENF_02691 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HGHAFENF_02692 2.4e-116 luxT K Bacterial regulatory proteins, tetR family
HGHAFENF_02693 3.5e-88 K Winged helix DNA-binding domain
HGHAFENF_02694 1.3e-136 T Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HGHAFENF_02695 1.7e-129 S WxL domain surface cell wall-binding
HGHAFENF_02696 1.5e-186 S Bacterial protein of unknown function (DUF916)
HGHAFENF_02697 0.0
HGHAFENF_02698 7.9e-161 ypuA S Protein of unknown function (DUF1002)
HGHAFENF_02699 5.5e-50 yvlA
HGHAFENF_02700 1.2e-95 K transcriptional regulator
HGHAFENF_02701 1e-90 ymdB S Macro domain protein
HGHAFENF_02702 1.5e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HGHAFENF_02703 2.3e-43 S Protein of unknown function (DUF1093)
HGHAFENF_02704 2e-77 S Threonine/Serine exporter, ThrE
HGHAFENF_02705 9.2e-133 thrE S Putative threonine/serine exporter
HGHAFENF_02706 5.2e-164 yvgN C Aldo keto reductase
HGHAFENF_02707 3.8e-152 ywkB S Membrane transport protein
HGHAFENF_02708 8.6e-311 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HGHAFENF_02709 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
HGHAFENF_02710 5.9e-85 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
HGHAFENF_02711 3e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HGHAFENF_02712 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HGHAFENF_02713 1.2e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HGHAFENF_02714 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HGHAFENF_02715 1.7e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HGHAFENF_02716 2.2e-254 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HGHAFENF_02717 3.1e-74 yabR J RNA binding
HGHAFENF_02718 1.1e-63 divIC D Septum formation initiator
HGHAFENF_02720 2.2e-42 yabO J S4 domain protein
HGHAFENF_02721 3.3e-289 yabM S Polysaccharide biosynthesis protein
HGHAFENF_02722 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HGHAFENF_02723 1.5e-100 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HGHAFENF_02724 3.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HGHAFENF_02725 6.4e-265 S Putative peptidoglycan binding domain
HGHAFENF_02726 2.1e-114 S (CBS) domain
HGHAFENF_02727 4.1e-84 S QueT transporter
HGHAFENF_02728 9.4e-189 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HGHAFENF_02729 9.3e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine
HGHAFENF_02730 9.4e-130 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
HGHAFENF_02731 2e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HGHAFENF_02732 3e-187 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HGHAFENF_02733 6.3e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HGHAFENF_02734 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HGHAFENF_02735 5e-134 P ATPases associated with a variety of cellular activities
HGHAFENF_02736 4.1e-128 ssuC2 U Binding-protein-dependent transport system inner membrane component
HGHAFENF_02737 8.5e-193 P ABC transporter, substratebinding protein
HGHAFENF_02738 0.0 kup P Transport of potassium into the cell
HGHAFENF_02739 1.6e-64 ndoA L Toxic component of a toxin-antitoxin (TA) module
HGHAFENF_02740 1.7e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HGHAFENF_02741 1e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HGHAFENF_02742 7.4e-307 uup S ABC transporter, ATP-binding protein
HGHAFENF_02743 1.4e-119 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HGHAFENF_02744 6.1e-109 ydiL S CAAX protease self-immunity
HGHAFENF_02745 1e-31 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HGHAFENF_02746 8.5e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HGHAFENF_02747 0.0 ydaO E amino acid
HGHAFENF_02748 2.7e-181 tagO 2.7.8.33, 2.7.8.35 M transferase
HGHAFENF_02749 2.8e-144 pstS P Phosphate
HGHAFENF_02750 1.7e-114 yvyE 3.4.13.9 S YigZ family
HGHAFENF_02751 7.4e-258 comFA L Helicase C-terminal domain protein
HGHAFENF_02752 4.8e-125 comFC S Competence protein
HGHAFENF_02753 3.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HGHAFENF_02754 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HGHAFENF_02755 3.2e-203 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HGHAFENF_02756 1.2e-216 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
HGHAFENF_02757 1.5e-132 K response regulator
HGHAFENF_02758 9.2e-251 phoR 2.7.13.3 T Histidine kinase
HGHAFENF_02759 3e-151 pstS P Phosphate
HGHAFENF_02760 1.5e-161 pstC P probably responsible for the translocation of the substrate across the membrane
HGHAFENF_02761 1.5e-155 pstA P Phosphate transport system permease protein PstA
HGHAFENF_02762 1.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HGHAFENF_02763 1e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HGHAFENF_02764 8.3e-117 phoU P Plays a role in the regulation of phosphate uptake
HGHAFENF_02765 2e-49 pspC KT positive regulation of macromolecule biosynthetic process
HGHAFENF_02766 9.2e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HGHAFENF_02767 1.4e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HGHAFENF_02768 1.9e-163 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HGHAFENF_02769 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HGHAFENF_02770 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HGHAFENF_02771 3.3e-26 3.2.2.10 S Belongs to the LOG family
HGHAFENF_02772 4.7e-255 nhaC C Na H antiporter NhaC
HGHAFENF_02773 1.5e-250 cycA E Amino acid permease
HGHAFENF_02774 1.8e-167 S Alpha/beta hydrolase of unknown function (DUF915)
HGHAFENF_02775 7.3e-86 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HGHAFENF_02776 4.1e-161 azoB GM NmrA-like family
HGHAFENF_02777 5.4e-66 K Winged helix DNA-binding domain
HGHAFENF_02778 7e-71 spx4 1.20.4.1 P ArsC family
HGHAFENF_02779 6.3e-66 yeaO S Protein of unknown function, DUF488
HGHAFENF_02780 4e-53
HGHAFENF_02781 5.3e-214 mutY L A G-specific adenine glycosylase
HGHAFENF_02782 1.9e-62
HGHAFENF_02783 1.3e-85
HGHAFENF_02784 2e-79 hsp3 O Belongs to the small heat shock protein (HSP20) family
HGHAFENF_02785 2.6e-55
HGHAFENF_02786 2.1e-14
HGHAFENF_02787 7.3e-115 GM NmrA-like family
HGHAFENF_02788 1.3e-81 elaA S GNAT family
HGHAFENF_02789 1.6e-158 EG EamA-like transporter family
HGHAFENF_02790 1.8e-119 S membrane
HGHAFENF_02791 1.4e-111 S VIT family
HGHAFENF_02792 1.3e-190 pva2 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HGHAFENF_02793 0.0 copB 3.6.3.4 P P-type ATPase
HGHAFENF_02794 9.4e-74 copR K Copper transport repressor CopY TcrY
HGHAFENF_02795 7.4e-40
HGHAFENF_02796 7.7e-73 S COG NOG18757 non supervised orthologous group
HGHAFENF_02797 2.5e-248 lmrB EGP Major facilitator Superfamily
HGHAFENF_02798 3.4e-25
HGHAFENF_02799 4.2e-49
HGHAFENF_02800 9.4e-65 ycgX S Protein of unknown function (DUF1398)
HGHAFENF_02801 5.2e-251 U Belongs to the purine-cytosine permease (2.A.39) family
HGHAFENF_02802 7.7e-214 mdtG EGP Major facilitator Superfamily
HGHAFENF_02803 1.1e-180 D Alpha beta
HGHAFENF_02804 3.1e-78 M1-874 K Domain of unknown function (DUF1836)
HGHAFENF_02805 1.9e-166 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HGHAFENF_02806 1e-139 S Belongs to the UPF0246 family
HGHAFENF_02807 6e-76
HGHAFENF_02808 1.1e-310 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
HGHAFENF_02809 1.2e-140
HGHAFENF_02811 2.4e-110 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HGHAFENF_02812 4.8e-40
HGHAFENF_02813 1.9e-127 cbiO P ABC transporter
HGHAFENF_02814 2.6e-149 P Cobalt transport protein
HGHAFENF_02815 4.8e-182 nikMN P PDGLE domain
HGHAFENF_02816 4.2e-121 K Crp-like helix-turn-helix domain
HGHAFENF_02817 1e-240 larA 5.1.2.1 S Domain of unknown function (DUF2088)
HGHAFENF_02818 2.4e-125 larB S AIR carboxylase
HGHAFENF_02819 6.3e-132 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HGHAFENF_02820 5e-75 larC 4.99.1.12 S Protein of unknown function DUF111
HGHAFENF_02821 1.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HGHAFENF_02822 2.8e-151 larE S NAD synthase
HGHAFENF_02823 8.7e-176 1.6.5.5 C Zinc-binding dehydrogenase
HGHAFENF_02824 2.2e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HGHAFENF_02825 9.1e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HGHAFENF_02826 2.5e-110 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HGHAFENF_02827 1.9e-204 cytX U Belongs to the purine-cytosine permease (2.A.39) family
HGHAFENF_02828 5.1e-136 S peptidase C26
HGHAFENF_02829 1.4e-303 L HIRAN domain
HGHAFENF_02830 9.9e-85 F NUDIX domain
HGHAFENF_02831 2.6e-250 yifK E Amino acid permease
HGHAFENF_02832 1.7e-120
HGHAFENF_02833 5.6e-149 ydjP I Alpha/beta hydrolase family
HGHAFENF_02834 0.0 pacL1 P P-type ATPase
HGHAFENF_02835 1.3e-300 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HGHAFENF_02836 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
HGHAFENF_02837 4.7e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HGHAFENF_02838 0.0 M domain protein
HGHAFENF_02839 6.2e-31 M dTDP-4-dehydrorhamnose reductase activity
HGHAFENF_02840 3.1e-175
HGHAFENF_02841 6.5e-33
HGHAFENF_02842 1.7e-39
HGHAFENF_02843 1.2e-64
HGHAFENF_02844 5.6e-68 S Immunity protein 63
HGHAFENF_02845 2.4e-38
HGHAFENF_02846 9.6e-120 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HGHAFENF_02847 4.8e-197 uhpT EGP Major facilitator Superfamily
HGHAFENF_02848 6.9e-147 3.1.3.102, 3.1.3.104 G Sucrose-6F-phosphate phosphohydrolase
HGHAFENF_02849 3.3e-166 K Transcriptional regulator
HGHAFENF_02850 1.4e-150 S hydrolase
HGHAFENF_02851 1.6e-255 brnQ U Component of the transport system for branched-chain amino acids
HGHAFENF_02852 2.1e-208 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HGHAFENF_02854 7.2e-32
HGHAFENF_02855 2.9e-17 plnR
HGHAFENF_02856 1.7e-117
HGHAFENF_02857 5.2e-23 plnK
HGHAFENF_02858 3.5e-24 plnJ
HGHAFENF_02859 3.7e-199 frlB M SIS domain
HGHAFENF_02860 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HGHAFENF_02861 4.8e-221 S Uncharacterized protein conserved in bacteria (DUF2325)
HGHAFENF_02862 1.3e-122 yyaQ S YjbR
HGHAFENF_02864 0.0 cadA P P-type ATPase
HGHAFENF_02865 1.1e-306 U Belongs to the BCCT transporter (TC 2.A.15) family
HGHAFENF_02866 6.2e-122 E GDSL-like Lipase/Acylhydrolase family
HGHAFENF_02867 1.4e-77
HGHAFENF_02868 8.1e-38 S Bacteriocin-protection, YdeI or OmpD-Associated
HGHAFENF_02869 5.6e-55 FG HIT domain
HGHAFENF_02870 2.9e-30 FG HIT domain
HGHAFENF_02871 7.7e-174 S Aldo keto reductase
HGHAFENF_02872 1.9e-52 yitW S Pfam:DUF59
HGHAFENF_02873 6.7e-161 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HGHAFENF_02874 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
HGHAFENF_02875 5e-195 blaA6 V Beta-lactamase
HGHAFENF_02876 6.2e-96 V VanZ like family
HGHAFENF_02878 4.6e-163 K Transcriptional regulator
HGHAFENF_02879 5.7e-163 akr5f 1.1.1.346 S reductase
HGHAFENF_02880 3.3e-166 S Oxidoreductase, aldo keto reductase family protein
HGHAFENF_02881 7.9e-79 K Winged helix DNA-binding domain
HGHAFENF_02882 6.4e-268 ycaM E amino acid
HGHAFENF_02883 8.3e-129 aroD 1.1.1.25, 4.2.1.10 E Type I 3-dehydroquinase
HGHAFENF_02884 2.7e-32
HGHAFENF_02885 0.0 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HGHAFENF_02886 0.0 M Bacterial Ig-like domain (group 3)
HGHAFENF_02887 1.1e-77 fld C Flavodoxin
HGHAFENF_02888 1.5e-233
HGHAFENF_02889 1.2e-100 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HGHAFENF_02890 1.3e-176 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HGHAFENF_02891 8.3e-152 EG EamA-like transporter family
HGHAFENF_02892 6.5e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HGHAFENF_02893 1.3e-129 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HGHAFENF_02894 1.9e-77 KT response to antibiotic
HGHAFENF_02895 1.5e-52 K Transcriptional regulator
HGHAFENF_02896 7.7e-72 XK27_06920 S Protein of unknown function (DUF1700)
HGHAFENF_02897 1.7e-128 S Putative adhesin
HGHAFENF_02898 0.0 scrA 2.7.1.193, 2.7.1.211 G phosphotransferase system
HGHAFENF_02899 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HGHAFENF_02900 3.7e-182 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
HGHAFENF_02901 3.9e-110 S DUF218 domain
HGHAFENF_02904 3.1e-08 S 4Fe-4S single cluster domain
HGHAFENF_02906 2.1e-08 2.7.7.7 L 3' exoribonuclease, RNase T-like
HGHAFENF_02908 1.6e-92 cadD P Cadmium resistance transporter
HGHAFENF_02909 1.9e-47 K Transcriptional regulator, ArsR family
HGHAFENF_02910 1.9e-116 S SNARE associated Golgi protein
HGHAFENF_02911 1.1e-46
HGHAFENF_02912 6.8e-72 T Belongs to the universal stress protein A family
HGHAFENF_02913 1.9e-237 EGP Major Facilitator Superfamily
HGHAFENF_02914 6.1e-111 S Phage Mu protein F like protein
HGHAFENF_02915 9.4e-97 nudC 1.3.7.1, 3.6.1.22 L NAD+ diphosphatase activity
HGHAFENF_02916 9e-189 V Abi-like protein
HGHAFENF_02917 5.2e-100 G hydrolase, family 16
HGHAFENF_02919 2.9e-20 wapA M COG3209 Rhs family protein
HGHAFENF_02920 9.8e-39 L Transposase and inactivated derivatives
HGHAFENF_02921 3.9e-156 L Integrase core domain
HGHAFENF_02922 1.1e-64 M Plasmid recombination enzyme
HGHAFENF_02923 2.9e-17 S PcfK-like protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)