ORF_ID e_value Gene_name EC_number CAZy COGs Description
EKBHDFBE_00001 2.9e-210 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
EKBHDFBE_00002 1.2e-166 cgeB S Spore maturation protein
EKBHDFBE_00003 7.5e-63 cgeA
EKBHDFBE_00004 6.1e-40 cgeC
EKBHDFBE_00005 9.1e-226 cgeD M maturation of the outermost layer of the spore
EKBHDFBE_00006 3.1e-136 yiiD K acetyltransferase
EKBHDFBE_00008 1.6e-26 yosT L Bacterial transcription activator, effector binding domain
EKBHDFBE_00010 1.2e-233 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EKBHDFBE_00011 7.4e-121 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EKBHDFBE_00012 2e-118 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EKBHDFBE_00013 1.5e-247 yodQ 3.5.1.16 E Acetylornithine deacetylase
EKBHDFBE_00014 1.6e-141 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
EKBHDFBE_00015 6.1e-271 kamA 5.4.3.2 E lysine 2,3-aminomutase
EKBHDFBE_00016 1.1e-43 yokU S YokU-like protein, putative antitoxin
EKBHDFBE_00017 1.7e-34 yozE S Belongs to the UPF0346 family
EKBHDFBE_00018 5.1e-50 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EKBHDFBE_00019 3.6e-120 yodN
EKBHDFBE_00021 1e-23 yozD S YozD-like protein
EKBHDFBE_00022 8.3e-100 yodM 3.6.1.27 I Acid phosphatase homologues
EKBHDFBE_00023 2.1e-54 yodL S YodL-like
EKBHDFBE_00025 4.2e-124 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
EKBHDFBE_00026 8.4e-148 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
EKBHDFBE_00027 8.3e-22 yodI
EKBHDFBE_00028 9.1e-119 yodH Q Methyltransferase
EKBHDFBE_00029 4.1e-251 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
EKBHDFBE_00030 4.7e-126 yydK K Transcriptional regulator
EKBHDFBE_00031 6e-282 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EKBHDFBE_00032 3.1e-265 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
EKBHDFBE_00033 3.8e-263 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EKBHDFBE_00034 1.8e-19 S Protein of unknown function (DUF3311)
EKBHDFBE_00035 3.8e-165 yodE E COG0346 Lactoylglutathione lyase and related lyases
EKBHDFBE_00036 5.8e-106 mhqD S Carboxylesterase
EKBHDFBE_00037 1.5e-104 yodC C nitroreductase
EKBHDFBE_00038 5.9e-52 yodB K transcriptional
EKBHDFBE_00039 4.4e-62 yodA S tautomerase
EKBHDFBE_00041 1.7e-76 yozR S COG0071 Molecular chaperone (small heat shock protein)
EKBHDFBE_00042 4.4e-158 rarD S -transporter
EKBHDFBE_00043 4.9e-23
EKBHDFBE_00044 1.8e-59 yojF S Protein of unknown function (DUF1806)
EKBHDFBE_00045 3.1e-124 yojG S deacetylase
EKBHDFBE_00046 4e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EKBHDFBE_00047 4.8e-233 norM V Multidrug efflux pump
EKBHDFBE_00049 6.7e-105 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EKBHDFBE_00050 1.8e-218 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
EKBHDFBE_00051 1.4e-215 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
EKBHDFBE_00052 4.5e-103 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EKBHDFBE_00053 1.9e-161 yojN S ATPase family associated with various cellular activities (AAA)
EKBHDFBE_00054 0.0 yojO P Von Willebrand factor
EKBHDFBE_00055 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
EKBHDFBE_00056 2.4e-202 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
EKBHDFBE_00057 9.7e-127 S Metallo-beta-lactamase superfamily
EKBHDFBE_00058 5.2e-157 yocS S -transporter
EKBHDFBE_00059 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EKBHDFBE_00060 1.5e-160 sodA 1.15.1.1 P Superoxide dismutase
EKBHDFBE_00061 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
EKBHDFBE_00062 3.6e-282 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
EKBHDFBE_00063 3.5e-31 yozC
EKBHDFBE_00064 2.4e-56 yozO S Bacterial PH domain
EKBHDFBE_00065 3.2e-36 yocN
EKBHDFBE_00066 1.9e-43 yozN
EKBHDFBE_00067 2.8e-87 yocM O Belongs to the small heat shock protein (HSP20) family
EKBHDFBE_00068 5.7e-09
EKBHDFBE_00069 3.1e-09 yocL
EKBHDFBE_00070 2.3e-60 dksA T general stress protein
EKBHDFBE_00071 3.7e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EKBHDFBE_00073 0.0 recQ 3.6.4.12 L DNA helicase
EKBHDFBE_00074 8.7e-127 yocH CBM50 M COG1388 FOG LysM repeat
EKBHDFBE_00076 8.1e-182 yocD 3.4.17.13 V peptidase S66
EKBHDFBE_00077 8.8e-92 yocC
EKBHDFBE_00078 3.3e-133 yocB J Protein required for attachment to host cells
EKBHDFBE_00079 1.2e-89 yozB S membrane
EKBHDFBE_00080 3e-119 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EKBHDFBE_00081 1.3e-54 czrA K transcriptional
EKBHDFBE_00082 5.1e-90 yobW
EKBHDFBE_00083 9.7e-124 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
EKBHDFBE_00084 5.8e-84 yobS K Transcriptional regulator
EKBHDFBE_00085 4.4e-121 yobQ K helix_turn_helix, arabinose operon control protein
EKBHDFBE_00086 7.8e-52 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
EKBHDFBE_00087 3.2e-31 K Helix-turn-helix XRE-family like proteins
EKBHDFBE_00088 2.7e-28 S DNA binding
EKBHDFBE_00089 3.7e-62
EKBHDFBE_00093 1.8e-44
EKBHDFBE_00094 1.6e-195
EKBHDFBE_00097 2.4e-09
EKBHDFBE_00102 6.3e-13 S HNH endonuclease
EKBHDFBE_00103 6.9e-14
EKBHDFBE_00107 7.9e-45 terS L Terminase, small subunit
EKBHDFBE_00108 4e-216 terL S Terminase
EKBHDFBE_00110 5e-144 S portal protein
EKBHDFBE_00111 1.5e-53 pi136 S Caudovirus prohead serine protease
EKBHDFBE_00112 3.2e-103 S capsid protein
EKBHDFBE_00113 3.7e-21 S Phage gp6-like head-tail connector protein
EKBHDFBE_00114 2.2e-19 S Phage head-tail joining protein
EKBHDFBE_00115 6e-32 S Bacteriophage HK97-gp10, putative tail-component
EKBHDFBE_00116 1.5e-09
EKBHDFBE_00117 2e-26 S Phage tail tube protein
EKBHDFBE_00118 1.6e-07
EKBHDFBE_00120 0.0 D Phage tail tape measure protein
EKBHDFBE_00121 5e-39 S Phage tail protein
EKBHDFBE_00122 7.7e-104 mur1 NU Prophage endopeptidase tail
EKBHDFBE_00123 5.9e-272 M Pectate lyase superfamily protein
EKBHDFBE_00124 2.3e-81 S Domain of unknown function (DUF2479)
EKBHDFBE_00125 1.4e-14
EKBHDFBE_00127 9.4e-27 bhlA S BhlA holin family
EKBHDFBE_00128 1.7e-25 xhlB S SPP1 phage holin
EKBHDFBE_00129 8.9e-47 M D-alanyl-D-alanine carboxypeptidase
EKBHDFBE_00131 1.6e-14 K Helix-turn-helix domain
EKBHDFBE_00134 3.4e-14 K Cro/C1-type HTH DNA-binding domain
EKBHDFBE_00139 1.8e-111 L Belongs to the 'phage' integrase family
EKBHDFBE_00142 2.5e-21
EKBHDFBE_00144 2.8e-263 flp V Beta-lactamase
EKBHDFBE_00147 1.3e-09
EKBHDFBE_00148 9.8e-32 yoaF
EKBHDFBE_00149 1.4e-25 yoaF
EKBHDFBE_00150 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EKBHDFBE_00151 2.1e-185 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EKBHDFBE_00152 1.5e-264 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
EKBHDFBE_00153 2.7e-206 yoaB EGP Major facilitator Superfamily
EKBHDFBE_00154 5.6e-114 yoxB
EKBHDFBE_00155 3.6e-35 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EKBHDFBE_00156 7.6e-121 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EKBHDFBE_00157 4.7e-61 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
EKBHDFBE_00158 4.2e-136 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EKBHDFBE_00159 3.5e-197 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EKBHDFBE_00160 1.3e-157 gltC K Transcriptional regulator
EKBHDFBE_00161 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
EKBHDFBE_00162 6.3e-287 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
EKBHDFBE_00163 4e-48 1.16.3.1 S Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EKBHDFBE_00164 1.6e-174 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
EKBHDFBE_00165 1.7e-146 gltR1 K Transcriptional regulator
EKBHDFBE_00166 9.5e-267 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EKBHDFBE_00167 1.5e-49 ybzH K Helix-turn-helix domain
EKBHDFBE_00168 4.7e-192 ybcL EGP Major facilitator Superfamily
EKBHDFBE_00169 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
EKBHDFBE_00170 1.9e-33 yoeD G Helix-turn-helix domain
EKBHDFBE_00171 3.6e-94 L Integrase
EKBHDFBE_00173 2.3e-93 yoeB S IseA DL-endopeptidase inhibitor
EKBHDFBE_00174 1.8e-238 yoeA V MATE efflux family protein
EKBHDFBE_00175 1e-176 yoxA 5.1.3.3 G Aldose 1-epimerase
EKBHDFBE_00176 1.2e-256 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
EKBHDFBE_00177 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKBHDFBE_00178 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
EKBHDFBE_00179 7.3e-62 yngL S Protein of unknown function (DUF1360)
EKBHDFBE_00180 1.8e-292 yngK T Glycosyl hydrolase-like 10
EKBHDFBE_00181 3.2e-206 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
EKBHDFBE_00182 7.7e-310 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EKBHDFBE_00183 1.7e-238 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
EKBHDFBE_00184 3.4e-29 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
EKBHDFBE_00185 5.9e-163 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
EKBHDFBE_00186 2.8e-132 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
EKBHDFBE_00187 1.6e-285 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EKBHDFBE_00188 5.9e-103 yngC S SNARE associated Golgi protein
EKBHDFBE_00189 9.5e-153 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
EKBHDFBE_00190 1.6e-67 yngA S membrane
EKBHDFBE_00191 1.2e-132 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
EKBHDFBE_00192 9.6e-250 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
EKBHDFBE_00193 4.8e-197 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EKBHDFBE_00194 2.6e-121 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EKBHDFBE_00195 1e-187 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EKBHDFBE_00196 2.7e-163 bioI 1.14.14.46 C Cytochrome P450
EKBHDFBE_00197 2.9e-112 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EKBHDFBE_00198 2.4e-105 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EKBHDFBE_00199 8.4e-121 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
EKBHDFBE_00200 1.3e-205 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EKBHDFBE_00201 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKBHDFBE_00202 1.5e-267 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKBHDFBE_00203 1.8e-237 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
EKBHDFBE_00204 1.3e-120 T Transcriptional regulatory protein, C terminal
EKBHDFBE_00205 4.2e-224 T PhoQ Sensor
EKBHDFBE_00206 1.4e-50 S Domain of unknown function (DUF4870)
EKBHDFBE_00207 7e-116 yndJ S YndJ-like protein
EKBHDFBE_00208 6.8e-78 yndH S Domain of unknown function (DUF4166)
EKBHDFBE_00209 3.3e-136 yndG S DoxX-like family
EKBHDFBE_00210 1.5e-248 agcS E Sodium alanine symporter
EKBHDFBE_00211 2.6e-45 ynfC
EKBHDFBE_00212 7.7e-13
EKBHDFBE_00213 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EKBHDFBE_00214 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EKBHDFBE_00215 7.3e-68 yccU S CoA-binding protein
EKBHDFBE_00216 6e-92 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EKBHDFBE_00217 3.3e-43 yneR S Belongs to the HesB IscA family
EKBHDFBE_00218 2.3e-47 yneQ
EKBHDFBE_00219 1.9e-71 yneP S Thioesterase-like superfamily
EKBHDFBE_00220 7.7e-33 tlp S Belongs to the Tlp family
EKBHDFBE_00223 3e-87 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EKBHDFBE_00224 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EKBHDFBE_00225 7.4e-15 sspO S Belongs to the SspO family
EKBHDFBE_00226 4.9e-19 sspP S Belongs to the SspP family
EKBHDFBE_00227 7.3e-59 hspX O Spore coat protein
EKBHDFBE_00228 1.3e-70 yneK S Protein of unknown function (DUF2621)
EKBHDFBE_00229 6.2e-74 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
EKBHDFBE_00230 1.5e-56 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
EKBHDFBE_00231 1.4e-122 ccdA O cytochrome c biogenesis protein
EKBHDFBE_00232 3e-23 ynzD S Spo0E like sporulation regulatory protein
EKBHDFBE_00233 3.9e-28 yneF S UPF0154 protein
EKBHDFBE_00234 1.9e-77 yneE S Sporulation inhibitor of replication protein sirA
EKBHDFBE_00235 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EKBHDFBE_00236 2.4e-31 ynzC S UPF0291 protein
EKBHDFBE_00237 1.6e-109 yneB L resolvase
EKBHDFBE_00238 2.9e-48 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
EKBHDFBE_00239 3.4e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EKBHDFBE_00240 7.8e-12 yoaW
EKBHDFBE_00241 8.3e-65 yndM S Protein of unknown function (DUF2512)
EKBHDFBE_00242 4.1e-142 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
EKBHDFBE_00244 2.2e-127 yndL S Replication protein
EKBHDFBE_00245 6.5e-75 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
EKBHDFBE_00246 8.4e-32 S TM2 domain
EKBHDFBE_00247 0.0 yobO M Pectate lyase superfamily protein
EKBHDFBE_00249 1.6e-91 yvgO
EKBHDFBE_00251 4.9e-116 AA10,CBM73 S Pfam:Chitin_bind_3
EKBHDFBE_00252 2.7e-186 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKBHDFBE_00253 1.7e-100 ynaE S Domain of unknown function (DUF3885)
EKBHDFBE_00257 4.8e-91 J Acetyltransferase (GNAT) domain
EKBHDFBE_00258 3e-131 yoaP 3.1.3.18 K YoaP-like
EKBHDFBE_00259 4e-10 ywlA S Uncharacterised protein family (UPF0715)
EKBHDFBE_00261 1.1e-30 S Protein of unknown function (DUF4025)
EKBHDFBE_00264 6.7e-179 adhP 1.1.1.1 C alcohol dehydrogenase
EKBHDFBE_00265 1.8e-68 S DinB family
EKBHDFBE_00267 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
EKBHDFBE_00268 1.9e-116 3.2.1.8 G Glycosyl hydrolases family 11
EKBHDFBE_00269 2.4e-273 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
EKBHDFBE_00270 9.5e-250 xylA 5.3.1.5 G Belongs to the xylose isomerase family
EKBHDFBE_00271 1.4e-204 xylR GK ROK family
EKBHDFBE_00272 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
EKBHDFBE_00273 1.1e-245 xynT G MFS/sugar transport protein
EKBHDFBE_00274 7.3e-212 cypA C Cytochrome P450
EKBHDFBE_00275 1.3e-116 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
EKBHDFBE_00276 1.1e-258 glnA 6.3.1.2 E glutamine synthetase
EKBHDFBE_00277 5.7e-65 glnR K transcriptional
EKBHDFBE_00278 1.4e-239 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
EKBHDFBE_00279 8.2e-227 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EKBHDFBE_00280 1.9e-175 spoVK O stage V sporulation protein K
EKBHDFBE_00281 5.6e-106 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EKBHDFBE_00282 1.5e-101 ymaB S MutT family
EKBHDFBE_00283 1.8e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EKBHDFBE_00284 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EKBHDFBE_00285 2.9e-58 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
EKBHDFBE_00286 2.3e-20 ymzA
EKBHDFBE_00287 1.6e-39
EKBHDFBE_00288 2.4e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
EKBHDFBE_00289 1.3e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EKBHDFBE_00290 2.7e-54 ymaF S YmaF family
EKBHDFBE_00292 2.1e-46 ebrA P Small Multidrug Resistance protein
EKBHDFBE_00293 5.7e-53 ebrB P Small Multidrug Resistance protein
EKBHDFBE_00294 3.1e-75 ymaD O redox protein, regulator of disulfide bond formation
EKBHDFBE_00295 1e-117 ymaC S Replication protein
EKBHDFBE_00297 1.4e-248 aprX O Belongs to the peptidase S8 family
EKBHDFBE_00298 7.6e-61 ymzB
EKBHDFBE_00299 4.4e-116 yoaK S Membrane
EKBHDFBE_00300 6.3e-70 nucB M Deoxyribonuclease NucA/NucB
EKBHDFBE_00301 1e-221 cypA C Cytochrome P450
EKBHDFBE_00302 0.0 pks13 HQ Beta-ketoacyl synthase
EKBHDFBE_00303 0.0 dhbF IQ polyketide synthase
EKBHDFBE_00304 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
EKBHDFBE_00305 0.0 Q Polyketide synthase of type I
EKBHDFBE_00306 0.0 rhiB IQ polyketide synthase
EKBHDFBE_00307 4e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
EKBHDFBE_00308 5.7e-138 pksH 4.2.1.18 I enoyl-CoA hydratase
EKBHDFBE_00309 2.9e-240 pksG 2.3.3.10 I synthase
EKBHDFBE_00310 3.8e-35 acpK IQ Phosphopantetheine attachment site
EKBHDFBE_00311 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EKBHDFBE_00312 2.3e-168 pksD Q Acyl transferase domain
EKBHDFBE_00313 2.8e-157 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EKBHDFBE_00314 3.2e-124 pksB 3.1.2.6 S Polyketide biosynthesis
EKBHDFBE_00315 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EKBHDFBE_00316 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EKBHDFBE_00317 4.5e-89 cotE S Spore coat protein
EKBHDFBE_00318 1.2e-65 ymcA 3.6.3.21 S Belongs to the UPF0342 family
EKBHDFBE_00319 8e-293 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EKBHDFBE_00320 3.1e-212 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EKBHDFBE_00321 5.8e-194 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
EKBHDFBE_00322 2.7e-36 spoVS S Stage V sporulation protein S
EKBHDFBE_00323 3.5e-151 ymdB S protein conserved in bacteria
EKBHDFBE_00324 2e-243 rny S Endoribonuclease that initiates mRNA decay
EKBHDFBE_00325 5.9e-203 pbpX V Beta-lactamase
EKBHDFBE_00326 8.4e-185 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EKBHDFBE_00327 4.3e-228 cinA 3.5.1.42 S Belongs to the CinA family
EKBHDFBE_00328 3.5e-100 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EKBHDFBE_00329 4.1e-132 ymfM S protein conserved in bacteria
EKBHDFBE_00330 1.5e-141 ymfK S Protein of unknown function (DUF3388)
EKBHDFBE_00331 2.8e-41 ymfJ S Protein of unknown function (DUF3243)
EKBHDFBE_00332 1.5e-124 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
EKBHDFBE_00333 3.6e-238 ymfH S zinc protease
EKBHDFBE_00334 1e-232 ymfF S Peptidase M16
EKBHDFBE_00335 0.0 ydgH S drug exporters of the RND superfamily
EKBHDFBE_00336 1.7e-73 K helix_turn_helix multiple antibiotic resistance protein
EKBHDFBE_00337 7.8e-228 ymfD EGP Major facilitator Superfamily
EKBHDFBE_00338 5.9e-129 ymfC K Transcriptional regulator
EKBHDFBE_00339 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
EKBHDFBE_00340 1.5e-29 S YlzJ-like protein
EKBHDFBE_00341 4.8e-130 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
EKBHDFBE_00342 1e-301 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EKBHDFBE_00343 8e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EKBHDFBE_00344 6.7e-218 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
EKBHDFBE_00345 3e-190 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EKBHDFBE_00346 3.2e-101 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
EKBHDFBE_00347 3.5e-155 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
EKBHDFBE_00348 1.3e-41 ymxH S YlmC YmxH family
EKBHDFBE_00349 9.8e-233 pepR S Belongs to the peptidase M16 family
EKBHDFBE_00350 1.8e-178 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
EKBHDFBE_00351 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
EKBHDFBE_00352 1.7e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EKBHDFBE_00353 3.5e-174 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
EKBHDFBE_00354 1.4e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EKBHDFBE_00355 2.1e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EKBHDFBE_00356 2.9e-44 ylxP S protein conserved in bacteria
EKBHDFBE_00357 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EKBHDFBE_00358 6.8e-47 ylxQ J ribosomal protein
EKBHDFBE_00359 2.3e-41 ylxR K nucleic-acid-binding protein implicated in transcription termination
EKBHDFBE_00360 1.6e-205 nusA K Participates in both transcription termination and antitermination
EKBHDFBE_00361 7.3e-80 rimP S Required for maturation of 30S ribosomal subunits
EKBHDFBE_00362 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EKBHDFBE_00363 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EKBHDFBE_00364 3.6e-230 rasP M zinc metalloprotease
EKBHDFBE_00365 8.9e-212 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
EKBHDFBE_00366 6.4e-137 cdsA 2.7.7.41 S Belongs to the CDS family
EKBHDFBE_00367 5e-142 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EKBHDFBE_00368 3.2e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EKBHDFBE_00369 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
EKBHDFBE_00370 1.5e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EKBHDFBE_00371 1.2e-129 rpsB J Belongs to the universal ribosomal protein uS2 family
EKBHDFBE_00372 5.7e-64 ylxL
EKBHDFBE_00373 3.6e-137 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EKBHDFBE_00374 9.5e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
EKBHDFBE_00375 4.5e-109 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
EKBHDFBE_00376 7.4e-80 cheW NT COG0835 Chemotaxis signal transduction protein
EKBHDFBE_00377 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
EKBHDFBE_00378 2.2e-188 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
EKBHDFBE_00379 2.7e-152 flhG D Belongs to the ParA family
EKBHDFBE_00380 6.3e-175 flhF N Flagellar biosynthesis regulator FlhF
EKBHDFBE_00381 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EKBHDFBE_00382 6e-186 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EKBHDFBE_00383 8.3e-129 fliR N Flagellar biosynthetic protein FliR
EKBHDFBE_00384 2e-37 fliQ N Role in flagellar biosynthesis
EKBHDFBE_00385 2.1e-109 fliP N Plays a role in the flagellum-specific transport system
EKBHDFBE_00386 1.6e-109 fliZ N Flagellar biosynthesis protein, FliO
EKBHDFBE_00387 2.7e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
EKBHDFBE_00388 2.3e-180 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EKBHDFBE_00389 3.3e-178 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EKBHDFBE_00390 2.8e-59 fliL N Controls the rotational direction of flagella during chemotaxis
EKBHDFBE_00391 7e-136 flgG N Flagellar basal body rod
EKBHDFBE_00392 1.2e-68 flgD N Flagellar basal body rod modification protein
EKBHDFBE_00393 3.2e-189 fliK N Flagellar hook-length control protein
EKBHDFBE_00394 4.1e-59 ylxF S MgtE intracellular N domain
EKBHDFBE_00395 2.9e-70 fliJ N Flagellar biosynthesis chaperone
EKBHDFBE_00396 5.2e-240 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
EKBHDFBE_00397 4.3e-90 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
EKBHDFBE_00398 8.7e-179 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EKBHDFBE_00399 1.8e-266 fliF N The M ring may be actively involved in energy transduction
EKBHDFBE_00400 1.4e-37 fliE N Flagellar hook-basal body
EKBHDFBE_00401 1.7e-73 flgC N Belongs to the flagella basal body rod proteins family
EKBHDFBE_00402 2.2e-61 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
EKBHDFBE_00403 1.6e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EKBHDFBE_00404 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EKBHDFBE_00405 6.3e-91 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EKBHDFBE_00406 2.2e-168 xerC L tyrosine recombinase XerC
EKBHDFBE_00407 2.9e-243 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EKBHDFBE_00408 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EKBHDFBE_00409 5e-162 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
EKBHDFBE_00410 3.4e-166 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EKBHDFBE_00411 1.3e-210 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
EKBHDFBE_00412 3.3e-43 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
EKBHDFBE_00413 6.4e-275 ylqG
EKBHDFBE_00414 6e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EKBHDFBE_00415 1e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EKBHDFBE_00416 3.2e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EKBHDFBE_00417 2.1e-134 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
EKBHDFBE_00418 7.1e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EKBHDFBE_00419 1.2e-59 ylqD S YlqD protein
EKBHDFBE_00420 5.7e-36 ylqC S Belongs to the UPF0109 family
EKBHDFBE_00421 1.9e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
EKBHDFBE_00422 2.1e-236 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EKBHDFBE_00423 9.5e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EKBHDFBE_00424 1.2e-172 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EKBHDFBE_00425 0.0 smc D Required for chromosome condensation and partitioning
EKBHDFBE_00426 3.7e-134 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EKBHDFBE_00427 8.2e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EKBHDFBE_00428 1.8e-128 IQ reductase
EKBHDFBE_00429 8.5e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EKBHDFBE_00430 5.6e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EKBHDFBE_00431 1.3e-91 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
EKBHDFBE_00432 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EKBHDFBE_00433 9.2e-156 sdaAA 4.3.1.17 E L-serine dehydratase
EKBHDFBE_00434 1.2e-117 sdaAB 4.3.1.17 E L-serine dehydratase
EKBHDFBE_00435 4e-298 yloV S kinase related to dihydroxyacetone kinase
EKBHDFBE_00436 2.7e-58 asp S protein conserved in bacteria
EKBHDFBE_00437 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
EKBHDFBE_00438 3.4e-112 thiN 2.7.6.2 H thiamine pyrophosphokinase
EKBHDFBE_00439 1.7e-114 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
EKBHDFBE_00440 1.3e-162 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EKBHDFBE_00441 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
EKBHDFBE_00442 9.6e-130 stp 3.1.3.16 T phosphatase
EKBHDFBE_00443 1.9e-203 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EKBHDFBE_00444 2.9e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EKBHDFBE_00445 2.4e-167 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EKBHDFBE_00446 1.5e-83 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EKBHDFBE_00447 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EKBHDFBE_00448 6.5e-221 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EKBHDFBE_00449 1.4e-27 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EKBHDFBE_00450 8.9e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
EKBHDFBE_00451 5.5e-40 ylzA S Belongs to the UPF0296 family
EKBHDFBE_00452 8.8e-151 yloC S stress-induced protein
EKBHDFBE_00453 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
EKBHDFBE_00454 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
EKBHDFBE_00455 1.1e-270 amyA 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
EKBHDFBE_00456 1.5e-72 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
EKBHDFBE_00457 3.2e-136 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
EKBHDFBE_00458 4.4e-138 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
EKBHDFBE_00459 4.7e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
EKBHDFBE_00460 2.3e-220 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
EKBHDFBE_00461 1.2e-175 cysP P phosphate transporter
EKBHDFBE_00462 3.3e-137 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
EKBHDFBE_00463 5.7e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EKBHDFBE_00464 2.2e-123 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EKBHDFBE_00465 5.2e-170 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EKBHDFBE_00466 1.6e-137 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
EKBHDFBE_00467 0.0 carB 6.3.5.5 F Belongs to the CarB family
EKBHDFBE_00468 5.3e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
EKBHDFBE_00469 2.4e-242 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EKBHDFBE_00470 1.8e-159 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
EKBHDFBE_00471 1.1e-229 pyrP F Xanthine uracil
EKBHDFBE_00472 7.9e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EKBHDFBE_00473 2.6e-166 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EKBHDFBE_00474 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EKBHDFBE_00475 1.1e-62 dksA T COG1734 DnaK suppressor protein
EKBHDFBE_00476 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EKBHDFBE_00477 5.2e-76 divIVA D Cell division initiation protein
EKBHDFBE_00478 3.7e-137 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
EKBHDFBE_00479 1.8e-41 yggT S membrane
EKBHDFBE_00480 4.2e-64 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EKBHDFBE_00481 4.8e-120 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EKBHDFBE_00482 3e-153 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
EKBHDFBE_00483 3.7e-38 ylmC S sporulation protein
EKBHDFBE_00484 1.6e-241 argE 3.5.1.16 E Acetylornithine deacetylase
EKBHDFBE_00485 1.8e-142 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
EKBHDFBE_00486 4.4e-138 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EKBHDFBE_00487 1.1e-124 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EKBHDFBE_00488 3.8e-165 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
EKBHDFBE_00489 0.0 bpr O COG1404 Subtilisin-like serine proteases
EKBHDFBE_00490 1.3e-202 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EKBHDFBE_00491 6.1e-233 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EKBHDFBE_00492 4.8e-132 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EKBHDFBE_00493 2.4e-164 murB 1.3.1.98 M cell wall formation
EKBHDFBE_00494 8.7e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EKBHDFBE_00495 1.4e-184 spoVE D Belongs to the SEDS family
EKBHDFBE_00496 1.3e-249 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EKBHDFBE_00497 9.9e-172 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EKBHDFBE_00498 1.6e-277 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EKBHDFBE_00499 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
EKBHDFBE_00500 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
EKBHDFBE_00501 1.6e-50 ftsL D Essential cell division protein
EKBHDFBE_00502 4.4e-169 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EKBHDFBE_00503 1.5e-76 mraZ K Belongs to the MraZ family
EKBHDFBE_00504 2.8e-299 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EKBHDFBE_00505 8.2e-152 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EKBHDFBE_00506 5.7e-88 ylbP K n-acetyltransferase
EKBHDFBE_00507 9.6e-82 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
EKBHDFBE_00508 7.9e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
EKBHDFBE_00509 4.7e-88 yceD S metal-binding, possibly nucleic acid-binding protein
EKBHDFBE_00510 2.4e-122 ylbM S Belongs to the UPF0348 family
EKBHDFBE_00511 9.9e-10 yqgA
EKBHDFBE_00512 2.2e-182 ylbL T Belongs to the peptidase S16 family
EKBHDFBE_00513 1.7e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
EKBHDFBE_00514 7.5e-209 ylbJ S Sporulation integral membrane protein YlbJ
EKBHDFBE_00515 1.9e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EKBHDFBE_00516 1e-96 rsmD 2.1.1.171 L Methyltransferase
EKBHDFBE_00517 1.8e-41 ylbG S UPF0298 protein
EKBHDFBE_00518 1.2e-71 ylbF S Belongs to the UPF0342 family
EKBHDFBE_00519 1.6e-35 ylbE S YlbE-like protein
EKBHDFBE_00520 2.1e-62 ylbD S Putative coat protein
EKBHDFBE_00521 1.4e-192 ylbC S protein with SCP PR1 domains
EKBHDFBE_00522 6.9e-72 ylbB T COG0517 FOG CBS domain
EKBHDFBE_00523 2.7e-58 ylbA S YugN-like family
EKBHDFBE_00524 3.2e-161 ctaG S cytochrome c oxidase
EKBHDFBE_00525 1e-51 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
EKBHDFBE_00526 1e-108 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
EKBHDFBE_00527 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EKBHDFBE_00528 1.7e-196 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
EKBHDFBE_00529 7.9e-163 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EKBHDFBE_00530 2.2e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
EKBHDFBE_00531 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EKBHDFBE_00532 1.6e-208 ftsW D Belongs to the SEDS family
EKBHDFBE_00533 2.5e-43 ylaN S Belongs to the UPF0358 family
EKBHDFBE_00534 9.8e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
EKBHDFBE_00535 5.7e-80 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EKBHDFBE_00536 3.3e-242 phoH T ATPase related to phosphate starvation-inducible protein PhoH
EKBHDFBE_00537 1.4e-99 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EKBHDFBE_00538 1.5e-32 ylaI S protein conserved in bacteria
EKBHDFBE_00539 1.7e-48 ylaH S YlaH-like protein
EKBHDFBE_00540 0.0 typA T GTP-binding protein TypA
EKBHDFBE_00541 1.9e-23 S Family of unknown function (DUF5325)
EKBHDFBE_00542 3.8e-44 ylaE
EKBHDFBE_00543 5.7e-14 sigC S Putative zinc-finger
EKBHDFBE_00544 4.7e-88 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
EKBHDFBE_00545 6.7e-38 ylaB
EKBHDFBE_00546 1.8e-177 ylaA
EKBHDFBE_00547 8.7e-287 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
EKBHDFBE_00548 1.9e-77 ykzC S Acetyltransferase (GNAT) family
EKBHDFBE_00549 6.7e-150 suhB 3.1.3.25 G Inositol monophosphatase
EKBHDFBE_00550 1.5e-22 ykzI
EKBHDFBE_00551 3.5e-117 yktB S Belongs to the UPF0637 family
EKBHDFBE_00552 2.2e-41 yktA S Belongs to the UPF0223 family
EKBHDFBE_00553 6.3e-271 speA 4.1.1.19 E Arginine
EKBHDFBE_00554 8.8e-134 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
EKBHDFBE_00555 4.7e-45 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
EKBHDFBE_00556 8.2e-260 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EKBHDFBE_00557 1.3e-235 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EKBHDFBE_00558 1.5e-175 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EKBHDFBE_00559 3.3e-203 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EKBHDFBE_00561 2e-197 V Beta-lactamase
EKBHDFBE_00562 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
EKBHDFBE_00563 0.0 Q Polyketide synthase of type I
EKBHDFBE_00564 0.0 Q Polyketide synthase of type I
EKBHDFBE_00565 0.0 Q Polyketide synthase of type I
EKBHDFBE_00566 0.0 Q Polyketide synthase of type I
EKBHDFBE_00567 0.0 Q polyketide synthase
EKBHDFBE_00568 0.0 Q Polyketide synthase of type I
EKBHDFBE_00569 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EKBHDFBE_00570 1.6e-93 recN L Putative cell-wall binding lipoprotein
EKBHDFBE_00572 3.2e-98 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EKBHDFBE_00573 3.9e-139 ykrA S hydrolases of the HAD superfamily
EKBHDFBE_00574 1.5e-29 ykzG S Belongs to the UPF0356 family
EKBHDFBE_00575 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EKBHDFBE_00576 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EKBHDFBE_00577 4.9e-114 ktrA P COG0569 K transport systems, NAD-binding component
EKBHDFBE_00578 4.5e-149 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
EKBHDFBE_00579 1.2e-236 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
EKBHDFBE_00580 1.1e-43 abrB K of stationary sporulation gene expression
EKBHDFBE_00581 2.2e-182 mreB D Rod-share determining protein MreBH
EKBHDFBE_00582 1.8e-12 S Uncharacterized protein YkpC
EKBHDFBE_00583 8.8e-234 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
EKBHDFBE_00584 2.2e-157 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EKBHDFBE_00585 1.5e-305 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EKBHDFBE_00586 4.1e-35 ykoA
EKBHDFBE_00587 4.3e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
EKBHDFBE_00588 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
EKBHDFBE_00589 3.5e-163 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
EKBHDFBE_00590 5.6e-130 fruR K Transcriptional regulator
EKBHDFBE_00591 1.1e-207 yknZ V ABC transporter (permease)
EKBHDFBE_00592 7.4e-121 macB V ABC transporter, ATP-binding protein
EKBHDFBE_00593 5.4e-177 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EKBHDFBE_00594 1.1e-103 yknW S Yip1 domain
EKBHDFBE_00595 8.2e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EKBHDFBE_00596 1.2e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
EKBHDFBE_00597 1.9e-84 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
EKBHDFBE_00598 2.8e-238 moeA 2.10.1.1 H molybdopterin
EKBHDFBE_00599 1.4e-184 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EKBHDFBE_00600 1.2e-98 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
EKBHDFBE_00601 5.9e-156 yknT
EKBHDFBE_00602 2.4e-96 rok K Repressor of ComK
EKBHDFBE_00603 9.3e-72 ykuV CO thiol-disulfide
EKBHDFBE_00605 8.6e-137 ykuT M Mechanosensitive ion channel
EKBHDFBE_00606 6.1e-38 ykuS S Belongs to the UPF0180 family
EKBHDFBE_00607 4.8e-210 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EKBHDFBE_00608 2.1e-99 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EKBHDFBE_00609 7.6e-74 fld C Flavodoxin
EKBHDFBE_00610 7.2e-161 ykuO
EKBHDFBE_00611 3.1e-86 fld C Flavodoxin
EKBHDFBE_00612 3.1e-164 ccpC K Transcriptional regulator
EKBHDFBE_00613 3.9e-75 ykuL S CBS domain
EKBHDFBE_00614 5.5e-26 ykzF S Antirepressor AbbA
EKBHDFBE_00615 1.9e-89 ykuK S Ribonuclease H-like
EKBHDFBE_00616 3.3e-36 ykuJ S protein conserved in bacteria
EKBHDFBE_00617 2.2e-229 ykuI T Diguanylate phosphodiesterase
EKBHDFBE_00619 2.4e-136 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKBHDFBE_00620 2.4e-145 ykuE S Metallophosphoesterase
EKBHDFBE_00621 1.1e-86 ykuD S protein conserved in bacteria
EKBHDFBE_00622 8.9e-237 ykuC EGP Major facilitator Superfamily
EKBHDFBE_00623 5.9e-82 ykyB S YkyB-like protein
EKBHDFBE_00624 1.4e-164 cheV 2.7.13.3 T Chemotaxis protein CheV
EKBHDFBE_00625 6e-10
EKBHDFBE_00626 2.8e-213 patA 2.6.1.1 E Aminotransferase
EKBHDFBE_00627 2.9e-289 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
EKBHDFBE_00628 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
EKBHDFBE_00629 4.4e-130 ykwD J protein with SCP PR1 domains
EKBHDFBE_00630 1.6e-157 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
EKBHDFBE_00631 1.2e-299 mcpC NT chemotaxis protein
EKBHDFBE_00632 1.6e-196 splB 4.1.99.14 L Spore photoproduct lyase
EKBHDFBE_00633 1.2e-35 splA S Transcriptional regulator
EKBHDFBE_00634 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EKBHDFBE_00635 1.6e-39 ptsH G phosphocarrier protein HPr
EKBHDFBE_00636 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EKBHDFBE_00637 1.2e-152 glcT K antiterminator
EKBHDFBE_00638 1.2e-169 ykvZ 5.1.1.1 K Transcriptional regulator
EKBHDFBE_00640 7.2e-203 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
EKBHDFBE_00641 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
EKBHDFBE_00642 1.8e-81 stoA CO thiol-disulfide
EKBHDFBE_00643 5.4e-237 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EKBHDFBE_00644 5.1e-105 ykvT 3.5.1.28 M Cell Wall Hydrolase
EKBHDFBE_00645 1.7e-27
EKBHDFBE_00646 1.3e-24 ykvS S protein conserved in bacteria
EKBHDFBE_00647 7.1e-43 ykvR S Protein of unknown function (DUF3219)
EKBHDFBE_00648 6.5e-95 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EKBHDFBE_00649 3.9e-136 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
EKBHDFBE_00650 3.8e-78 queD 4.1.2.50, 4.2.3.12 H synthase
EKBHDFBE_00651 2.1e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EKBHDFBE_00652 7.9e-181
EKBHDFBE_00653 1.4e-171 ykvI S membrane
EKBHDFBE_00654 0.0 clpE O Belongs to the ClpA ClpB family
EKBHDFBE_00655 6.6e-137 motA N flagellar motor
EKBHDFBE_00656 2.2e-124 motB N Flagellar motor protein
EKBHDFBE_00657 5.5e-77 ykvE K transcriptional
EKBHDFBE_00658 4.2e-270 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
EKBHDFBE_00659 5.2e-11 S Spo0E like sporulation regulatory protein
EKBHDFBE_00660 8.9e-90 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EKBHDFBE_00661 2e-109 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
EKBHDFBE_00662 4.7e-131 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EKBHDFBE_00663 2.6e-222 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
EKBHDFBE_00664 4e-223 mtnE 2.6.1.83 E Aminotransferase
EKBHDFBE_00665 3.6e-137 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EKBHDFBE_00666 2.1e-216 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EKBHDFBE_00667 5.5e-192 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EKBHDFBE_00669 2.8e-77 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EKBHDFBE_00670 0.0 kinE 2.7.13.3 T Histidine kinase
EKBHDFBE_00671 5.5e-189 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
EKBHDFBE_00672 1.7e-18 ykzE
EKBHDFBE_00673 1.8e-111 ydfR S Protein of unknown function (DUF421)
EKBHDFBE_00674 1.6e-236 ktrB P COG0168 Trk-type K transport systems, membrane components
EKBHDFBE_00675 3.8e-154 htpX O Belongs to the peptidase M48B family
EKBHDFBE_00676 3e-122 ykrK S Domain of unknown function (DUF1836)
EKBHDFBE_00677 3.6e-25 sspD S small acid-soluble spore protein
EKBHDFBE_00678 2.9e-173 rsgI S Anti-sigma factor N-terminus
EKBHDFBE_00679 2.9e-126 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EKBHDFBE_00680 2.1e-127 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
EKBHDFBE_00681 5.7e-95 ykoX S membrane-associated protein
EKBHDFBE_00682 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
EKBHDFBE_00683 4.9e-154 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EKBHDFBE_00684 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
EKBHDFBE_00685 1.2e-97 ykoP G polysaccharide deacetylase
EKBHDFBE_00686 2.1e-79 ykoM K transcriptional
EKBHDFBE_00687 4.4e-25 ykoL
EKBHDFBE_00688 1.6e-15
EKBHDFBE_00689 7.8e-52 tnrA K transcriptional
EKBHDFBE_00690 6.9e-240 mgtE P Acts as a magnesium transporter
EKBHDFBE_00692 1.1e-236 ydhD M Glycosyl hydrolase
EKBHDFBE_00693 7.9e-95 ykoE S ABC-type cobalt transport system, permease component
EKBHDFBE_00694 7e-279 P ABC transporter, ATP-binding protein
EKBHDFBE_00695 1.1e-125 ykoC P Cobalt transport protein
EKBHDFBE_00696 3.8e-140 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EKBHDFBE_00697 4.4e-172 isp O Belongs to the peptidase S8 family
EKBHDFBE_00698 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EKBHDFBE_00699 2e-118 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
EKBHDFBE_00700 4.4e-206 hcaT 1.5.1.2 EGP Major facilitator Superfamily
EKBHDFBE_00701 4.6e-121 3.2.1.4 GH5,GH9 K Collagen triple helix repeat
EKBHDFBE_00702 6.1e-189 M Glycosyl transferase family 2
EKBHDFBE_00704 5.5e-55 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EKBHDFBE_00705 1.6e-67 ohrB O Organic hydroperoxide resistance protein
EKBHDFBE_00706 2.2e-77 ohrR K COG1846 Transcriptional regulators
EKBHDFBE_00707 6.9e-69 ohrA O Organic hydroperoxide resistance protein
EKBHDFBE_00708 1.3e-221 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EKBHDFBE_00709 6.8e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EKBHDFBE_00710 9.8e-166 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
EKBHDFBE_00711 2.9e-48 ykkD P Multidrug resistance protein
EKBHDFBE_00712 1.7e-47 ykkC P Multidrug resistance protein
EKBHDFBE_00713 1.9e-92 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EKBHDFBE_00714 4.1e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
EKBHDFBE_00715 2.9e-143 ykgA E Amidinotransferase
EKBHDFBE_00716 7.8e-199 pgl 3.1.1.31 G 6-phosphogluconolactonase
EKBHDFBE_00717 3e-176 ykfD E Belongs to the ABC transporter superfamily
EKBHDFBE_00718 4.6e-155 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EKBHDFBE_00719 7e-190 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
EKBHDFBE_00720 4.7e-171 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
EKBHDFBE_00721 1.7e-309 dppE E ABC transporter substrate-binding protein
EKBHDFBE_00722 2.9e-182 dppD P Belongs to the ABC transporter superfamily
EKBHDFBE_00723 8.2e-171 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKBHDFBE_00724 9.5e-156 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKBHDFBE_00725 1.3e-153 dppA E D-aminopeptidase
EKBHDFBE_00726 1.1e-262 yubD P Major Facilitator Superfamily
EKBHDFBE_00727 3.6e-212 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EKBHDFBE_00729 5.1e-176 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EKBHDFBE_00730 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EKBHDFBE_00731 1.3e-176 mhqA E COG0346 Lactoylglutathione lyase and related lyases
EKBHDFBE_00732 9.4e-242 steT E amino acid
EKBHDFBE_00733 3.6e-111 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
EKBHDFBE_00734 5.8e-175 pit P phosphate transporter
EKBHDFBE_00735 1.9e-130 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
EKBHDFBE_00736 4.3e-22 spoIISB S Stage II sporulation protein SB
EKBHDFBE_00737 7.1e-161 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EKBHDFBE_00738 2.8e-36 xhlB S SPP1 phage holin
EKBHDFBE_00739 2.8e-36 xhlA S Haemolysin XhlA
EKBHDFBE_00740 4.8e-129 xepA
EKBHDFBE_00741 2.1e-25 xkdX
EKBHDFBE_00743 1.6e-160
EKBHDFBE_00744 1.2e-26
EKBHDFBE_00745 1.4e-85 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
EKBHDFBE_00746 1.9e-165 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
EKBHDFBE_00747 2.7e-57 xkdS S Protein of unknown function (DUF2634)
EKBHDFBE_00748 1.9e-32 xkdR S Protein of unknown function (DUF2577)
EKBHDFBE_00749 5.5e-162 xkdQ 3.2.1.96 G NLP P60 protein
EKBHDFBE_00750 3.3e-110 xkdP S Lysin motif
EKBHDFBE_00751 4.2e-224 xkdO L Transglycosylase SLT domain
EKBHDFBE_00754 2.3e-75 O Hsp20/alpha crystallin family
EKBHDFBE_00755 2.8e-239 pre D plasmid recombination enzyme
EKBHDFBE_00756 9.4e-83 K Transcriptional regulator
EKBHDFBE_00758 1e-195 L Replication protein
EKBHDFBE_00759 3.8e-16
EKBHDFBE_00762 1.3e-48 U TraM recognition site of TraD and TraG
EKBHDFBE_00763 5.5e-22 yddB S Conjugative transposon protein TcpC
EKBHDFBE_00767 4.8e-114 yddE S AAA-like domain
EKBHDFBE_00769 9.5e-36 M Psort location CytoplasmicMembrane, score
EKBHDFBE_00772 8.6e-73 yddH CBM50 M Lysozyme-like
EKBHDFBE_00773 1.1e-10 yddI
EKBHDFBE_00775 1.1e-25 abrB K Transition state
EKBHDFBE_00778 8.8e-124 S SMART Tetratricopeptide domain protein
EKBHDFBE_00782 2.3e-34 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EKBHDFBE_00786 8.2e-43 3.1.31.1 L Staphylococcal nuclease homologues
EKBHDFBE_00787 6.7e-79 S SprT-like family
EKBHDFBE_00789 4.7e-26
EKBHDFBE_00790 7.6e-21
EKBHDFBE_00792 6e-10
EKBHDFBE_00793 2.4e-127
EKBHDFBE_00796 1.3e-229 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKBHDFBE_00798 9.2e-15
EKBHDFBE_00801 2.6e-18 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
EKBHDFBE_00802 1e-17 V VanZ like family
EKBHDFBE_00804 1e-11
EKBHDFBE_00805 3.5e-51 yvrI K COG1191 DNA-directed RNA polymerase specialized sigma subunit
EKBHDFBE_00806 1.3e-08 S YvrJ protein family
EKBHDFBE_00808 3.1e-45
EKBHDFBE_00812 2.6e-27
EKBHDFBE_00816 5.7e-118 L Belongs to the 'phage' integrase family
EKBHDFBE_00817 8e-71
EKBHDFBE_00818 1.4e-31 V HNH endonuclease
EKBHDFBE_00821 5e-24 V HNH endonuclease
EKBHDFBE_00822 1.1e-14 S Bacterial PH domain
EKBHDFBE_00823 4.7e-45 ydbT S Bacterial PH domain
EKBHDFBE_00825 5e-09
EKBHDFBE_00827 6.5e-26 S Repressor of ComK
EKBHDFBE_00828 9.7e-19 abrB K SpoVT / AbrB like domain
EKBHDFBE_00833 1.5e-12 sftA D Belongs to the FtsK SpoIIIE SftA family
EKBHDFBE_00835 6.1e-13 S Protein of unknown function (DUF1064)
EKBHDFBE_00850 1.5e-40 nucA M Deoxyribonuclease NucA/NucB
EKBHDFBE_00853 2.4e-136 pdaB 3.5.1.104 G Polysaccharide deacetylase
EKBHDFBE_00854 1.6e-103 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
EKBHDFBE_00855 9.6e-79 gerD
EKBHDFBE_00856 1e-193 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
EKBHDFBE_00857 6.9e-130 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EKBHDFBE_00858 1.4e-75 ybaK S Protein of unknown function (DUF2521)
EKBHDFBE_00859 2.5e-138 ybaJ Q Methyltransferase domain
EKBHDFBE_00860 6.1e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
EKBHDFBE_00861 7e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EKBHDFBE_00862 1.4e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EKBHDFBE_00863 1.2e-135 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EKBHDFBE_00864 9.2e-145 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EKBHDFBE_00865 4.4e-152 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EKBHDFBE_00866 4.6e-58 rplQ J Ribosomal protein L17
EKBHDFBE_00867 5.8e-169 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EKBHDFBE_00868 1.4e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EKBHDFBE_00869 6.8e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EKBHDFBE_00870 9.1e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
EKBHDFBE_00871 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EKBHDFBE_00872 5.9e-140 map 3.4.11.18 E Methionine aminopeptidase
EKBHDFBE_00873 7e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EKBHDFBE_00874 9.6e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EKBHDFBE_00875 9e-72 rplO J binds to the 23S rRNA
EKBHDFBE_00876 8.2e-24 rpmD J Ribosomal protein L30
EKBHDFBE_00877 6.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EKBHDFBE_00878 5.7e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EKBHDFBE_00879 9.6e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EKBHDFBE_00880 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EKBHDFBE_00881 1.9e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EKBHDFBE_00882 3.3e-92 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EKBHDFBE_00883 1.8e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EKBHDFBE_00884 2.5e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EKBHDFBE_00885 6.6e-38 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EKBHDFBE_00886 2.2e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
EKBHDFBE_00887 6.5e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EKBHDFBE_00888 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EKBHDFBE_00889 4.2e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EKBHDFBE_00890 3.1e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EKBHDFBE_00891 1.1e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EKBHDFBE_00892 3.3e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EKBHDFBE_00893 6.7e-105 rplD J Forms part of the polypeptide exit tunnel
EKBHDFBE_00894 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EKBHDFBE_00895 9.7e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
EKBHDFBE_00896 7e-170 ybaC 3.4.11.5 S Alpha/beta hydrolase family
EKBHDFBE_00897 3e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EKBHDFBE_00898 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EKBHDFBE_00899 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EKBHDFBE_00900 4.2e-71 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EKBHDFBE_00901 1e-32 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
EKBHDFBE_00902 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EKBHDFBE_00903 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EKBHDFBE_00904 2.4e-107 rsmC 2.1.1.172 J Methyltransferase
EKBHDFBE_00905 2e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EKBHDFBE_00906 1.1e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EKBHDFBE_00907 1.2e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EKBHDFBE_00908 9.6e-71 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EKBHDFBE_00909 7e-95 nusG K Participates in transcription elongation, termination and antitermination
EKBHDFBE_00910 9.1e-23 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EKBHDFBE_00911 5.7e-115 sigH K Belongs to the sigma-70 factor family
EKBHDFBE_00912 8.8e-87 yacP S RNA-binding protein containing a PIN domain
EKBHDFBE_00913 3.5e-132 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EKBHDFBE_00914 1.1e-69 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EKBHDFBE_00915 1e-270 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
EKBHDFBE_00916 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
EKBHDFBE_00917 2.1e-274 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EKBHDFBE_00918 2.2e-84 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
EKBHDFBE_00919 1.1e-121 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
EKBHDFBE_00920 7.5e-192 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
EKBHDFBE_00921 1.6e-194 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EKBHDFBE_00922 3.5e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EKBHDFBE_00923 0.0 clpC O Belongs to the ClpA ClpB family
EKBHDFBE_00924 1.1e-200 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
EKBHDFBE_00925 4e-60 mcsA 2.7.14.1 S protein with conserved CXXC pairs
EKBHDFBE_00926 1.7e-76 ctsR K Belongs to the CtsR family
EKBHDFBE_00927 2.2e-154 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EKBHDFBE_00928 9.4e-183 corA P Mediates influx of magnesium ions
EKBHDFBE_00929 2.8e-29
EKBHDFBE_00930 4e-140 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
EKBHDFBE_00931 1.4e-152 pdaA G deacetylase
EKBHDFBE_00932 2.4e-26 yfjT
EKBHDFBE_00933 2.9e-215 yfkA S YfkB-like domain
EKBHDFBE_00934 9.8e-144 yfkC M Mechanosensitive ion channel
EKBHDFBE_00935 3.6e-140 yfkD S YfkD-like protein
EKBHDFBE_00936 5.5e-184 cax P COG0387 Ca2 H antiporter
EKBHDFBE_00937 1.4e-212 ycaD EGP COG0477 Permeases of the major facilitator superfamily
EKBHDFBE_00939 4.1e-142 yihY S Belongs to the UPF0761 family
EKBHDFBE_00940 1.5e-47 yfkI S gas vesicle protein
EKBHDFBE_00941 3.9e-81 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EKBHDFBE_00942 7.8e-29 yfkK S Belongs to the UPF0435 family
EKBHDFBE_00943 1.2e-192 ydiM EGP Major facilitator Superfamily
EKBHDFBE_00944 3.1e-128 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
EKBHDFBE_00945 2.7e-160 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EKBHDFBE_00946 4.7e-180 K helix_turn _helix lactose operon repressor
EKBHDFBE_00947 3.8e-90 yfkM 1.11.1.6, 3.5.1.124 S protease
EKBHDFBE_00948 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
EKBHDFBE_00949 4.4e-184 yibE S YibE/F-like protein
EKBHDFBE_00950 6.7e-123 yibF S YibE/F-like protein
EKBHDFBE_00951 8.7e-119 yfkO C nitroreductase
EKBHDFBE_00952 7.9e-126 treR K transcriptional
EKBHDFBE_00953 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
EKBHDFBE_00954 5.7e-245 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EKBHDFBE_00955 2e-39 ydgB S Spore germination protein gerPA/gerPF
EKBHDFBE_00956 2.3e-37 ydgA S Spore germination protein gerPA/gerPF
EKBHDFBE_00957 9.1e-77 cotP O Belongs to the small heat shock protein (HSP20) family
EKBHDFBE_00958 4.7e-61 yhdN S Domain of unknown function (DUF1992)
EKBHDFBE_00959 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
EKBHDFBE_00960 2.8e-73 yfmQ S Uncharacterised protein from bacillus cereus group
EKBHDFBE_00961 8.6e-246 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
EKBHDFBE_00962 3.3e-135 map 3.4.11.18 E Methionine aminopeptidase
EKBHDFBE_00963 5.8e-49 yflH S Protein of unknown function (DUF3243)
EKBHDFBE_00964 5.8e-18 yflI
EKBHDFBE_00965 4.4e-14 yflJ S Protein of unknown function (DUF2639)
EKBHDFBE_00966 1.2e-117 yflK S protein conserved in bacteria
EKBHDFBE_00967 1.7e-41 acyP 3.6.1.7 C Belongs to the acylphosphatase family
EKBHDFBE_00968 3.9e-209 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EKBHDFBE_00969 7.4e-141 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
EKBHDFBE_00970 1.8e-221 citM C Citrate transporter
EKBHDFBE_00971 4.1e-170 yflP S Tripartite tricarboxylate transporter family receptor
EKBHDFBE_00972 2.3e-114 citT T response regulator
EKBHDFBE_00973 8.1e-272 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
EKBHDFBE_00974 1.4e-81 srtA 3.4.22.70 M Sortase family
EKBHDFBE_00975 0.0 M1-568 M cell wall anchor domain
EKBHDFBE_00976 5.3e-150 M1-574 T Transcriptional regulatory protein, C terminal
EKBHDFBE_00977 0.0 ywpD T PhoQ Sensor
EKBHDFBE_00978 4.5e-78 M1-820 Q Collagen triple helix repeat (20 copies)
EKBHDFBE_01002 7.3e-72 tspO T membrane
EKBHDFBE_01003 1.7e-123 dksA T COG1734 DnaK suppressor protein
EKBHDFBE_01004 5.9e-258 menF 5.4.4.2 HQ Isochorismate synthase
EKBHDFBE_01005 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EKBHDFBE_01006 7.9e-146 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
EKBHDFBE_01007 2.3e-153 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EKBHDFBE_01008 2.2e-268 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
EKBHDFBE_01009 5.8e-208 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
EKBHDFBE_01010 3e-24 S Domain of Unknown Function (DUF1540)
EKBHDFBE_01011 1.1e-181 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
EKBHDFBE_01012 4.1e-245 cydA 1.10.3.14 C oxidase, subunit
EKBHDFBE_01013 1.3e-40 rpmE2 J Ribosomal protein L31
EKBHDFBE_01014 3.7e-102 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
EKBHDFBE_01015 3.3e-38 yidD S Could be involved in insertion of integral membrane proteins into the membrane
EKBHDFBE_01016 8.1e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EKBHDFBE_01017 2.5e-74 ytkA S YtkA-like
EKBHDFBE_01019 1.1e-74 dps P Belongs to the Dps family
EKBHDFBE_01020 1e-58 ytkC S Bacteriophage holin family
EKBHDFBE_01021 6.3e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
EKBHDFBE_01022 2.9e-132 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
EKBHDFBE_01023 6.2e-140 ytlC P ABC transporter
EKBHDFBE_01024 9.5e-178 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
EKBHDFBE_01025 1.1e-144 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
EKBHDFBE_01026 2.1e-38 ytmB S Protein of unknown function (DUF2584)
EKBHDFBE_01027 9.7e-302 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EKBHDFBE_01028 3.6e-224 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EKBHDFBE_01029 0.0 asnB 6.3.5.4 E Asparagine synthase
EKBHDFBE_01030 8.5e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
EKBHDFBE_01031 8.4e-61 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EKBHDFBE_01032 1.6e-148 ytpA 3.1.1.5 I Alpha beta hydrolase
EKBHDFBE_01033 2.4e-206 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
EKBHDFBE_01034 2e-130 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
EKBHDFBE_01036 1.3e-102 ytqB J Putative rRNA methylase
EKBHDFBE_01037 3.7e-57 yhcC S Fe-S oxidoreductase
EKBHDFBE_01038 1.5e-94 yhcC S Fe-S oxidoreductase
EKBHDFBE_01039 2.7e-278 norB EGP COG0477 Permeases of the major facilitator superfamily
EKBHDFBE_01040 8.1e-115 nrsA Q Thioesterase domain
EKBHDFBE_01041 1e-155 C Nitroreductase
EKBHDFBE_01042 7.5e-19
EKBHDFBE_01043 6.3e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
EKBHDFBE_01044 1.3e-73 xkdM S Phage tail tube protein
EKBHDFBE_01045 2.2e-225 xkdK S Phage tail sheath C-terminal domain
EKBHDFBE_01046 1.4e-14
EKBHDFBE_01047 2.8e-57 xkdJ
EKBHDFBE_01048 2.9e-58 xkdI S Bacteriophage HK97-gp10, putative tail-component
EKBHDFBE_01049 5.6e-40 yqbH S Domain of unknown function (DUF3599)
EKBHDFBE_01050 9.6e-46 yqbG S Protein of unknown function (DUF3199)
EKBHDFBE_01051 1.7e-157 xkdG S Phage capsid family
EKBHDFBE_01052 4.7e-93 xkdF 2.1.1.72 L Putative phage serine protease XkdF
EKBHDFBE_01053 6.2e-239 yqbA S portal protein
EKBHDFBE_01054 7.9e-209 xtmB S phage terminase, large subunit
EKBHDFBE_01055 1.3e-108 xtmA L phage terminase small subunit
EKBHDFBE_01056 4.2e-81 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
EKBHDFBE_01057 3.8e-09 yqaO S Phage-like element PBSX protein XtrA
EKBHDFBE_01060 6.9e-113 xkdC L Bacterial dnaA protein
EKBHDFBE_01061 1.5e-104 xkdB K sequence-specific DNA binding
EKBHDFBE_01063 1.7e-54 xre K Helix-turn-helix XRE-family like proteins
EKBHDFBE_01064 5.2e-107 xkdA E IrrE N-terminal-like domain
EKBHDFBE_01065 3.1e-99 yjqB S phage-related replication protein
EKBHDFBE_01066 8.8e-60 yjqA S Bacterial PH domain
EKBHDFBE_01067 6.7e-165 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
EKBHDFBE_01069 5.5e-214 S response regulator aspartate phosphatase
EKBHDFBE_01070 2.9e-76 yjoA S DinB family
EKBHDFBE_01071 4.5e-127 MA20_18170 S membrane transporter protein
EKBHDFBE_01073 3.3e-133 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
EKBHDFBE_01074 2.6e-86 T Transcriptional regulatory protein, C terminal
EKBHDFBE_01075 1.2e-163 uxaA 4.2.1.7, 4.4.1.24 G Altronate
EKBHDFBE_01076 7.3e-178 exuR K transcriptional
EKBHDFBE_01077 1e-76 uxaC 5.3.1.12 G glucuronate isomerase
EKBHDFBE_01078 4.2e-217 yjlD 1.6.99.3 C NADH dehydrogenase
EKBHDFBE_01079 2.4e-66 yjlC S Protein of unknown function (DUF1641)
EKBHDFBE_01080 7.2e-86 yjlB S Cupin domain
EKBHDFBE_01081 3.4e-172 yjlA EG Putative multidrug resistance efflux transporter
EKBHDFBE_01082 4.5e-124 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
EKBHDFBE_01083 1.2e-116 ybbM S transport system, permease component
EKBHDFBE_01084 1.6e-141 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
EKBHDFBE_01085 3.9e-29
EKBHDFBE_01086 3e-215 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EKBHDFBE_01087 5.3e-215 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
EKBHDFBE_01088 3.9e-85 yjgD S Protein of unknown function (DUF1641)
EKBHDFBE_01089 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
EKBHDFBE_01090 3.5e-92 yjgB S Domain of unknown function (DUF4309)
EKBHDFBE_01091 2.6e-62 T PhoQ Sensor
EKBHDFBE_01092 1.4e-20 yjfB S Putative motility protein
EKBHDFBE_01093 8.3e-103 yhiD S MgtC SapB transporter
EKBHDFBE_01094 2e-52 K helix_turn_helix multiple antibiotic resistance protein
EKBHDFBE_01095 1.3e-33
EKBHDFBE_01096 2.9e-117 5.4.2.6 S Haloacid dehalogenase-like hydrolase
EKBHDFBE_01097 1.6e-137 lacR K COG1349 Transcriptional regulators of sugar metabolism
EKBHDFBE_01098 1.7e-278 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
EKBHDFBE_01099 7.6e-49 lacF 2.7.1.207 G phosphotransferase system
EKBHDFBE_01100 2e-297 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EKBHDFBE_01101 3.4e-208 ganA 3.2.1.89 G arabinogalactan
EKBHDFBE_01103 6.5e-76 napB K helix_turn_helix multiple antibiotic resistance protein
EKBHDFBE_01104 2.3e-238 yfjF EGP Belongs to the major facilitator superfamily
EKBHDFBE_01105 3.5e-45 yjcS S Antibiotic biosynthesis monooxygenase
EKBHDFBE_01106 1.9e-156 bla 3.5.2.6 V beta-lactamase
EKBHDFBE_01110 7.4e-29 N Kelch motif
EKBHDFBE_01112 8.4e-28 S Bacillus cereus group antimicrobial protein
EKBHDFBE_01114 9.7e-170 3.4.24.40 S amine dehydrogenase activity
EKBHDFBE_01116 1.9e-08 S Domain of unknown function (DUF4879)
EKBHDFBE_01117 5.6e-103 1.1.1.169 H 2-dehydropantoate 2-reductase
EKBHDFBE_01118 8.7e-76 yokH G SMI1 / KNR4 family
EKBHDFBE_01119 9.8e-31
EKBHDFBE_01120 1.1e-72 yobL S Bacterial EndoU nuclease
EKBHDFBE_01121 1.4e-53
EKBHDFBE_01123 3.1e-212 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EKBHDFBE_01124 1.7e-207 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EKBHDFBE_01125 7e-122 yjcH P COG2382 Enterochelin esterase and related enzymes
EKBHDFBE_01126 7e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
EKBHDFBE_01127 3.6e-70 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EKBHDFBE_01128 2.5e-33 K SpoVT / AbrB like domain
EKBHDFBE_01129 7.9e-129 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
EKBHDFBE_01130 3e-117 S ABC-2 type transporter
EKBHDFBE_01131 1.9e-62 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
EKBHDFBE_01132 2e-56 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
EKBHDFBE_01133 1.4e-32
EKBHDFBE_01134 0.0 yjcD 3.6.4.12 L DNA helicase
EKBHDFBE_01135 1.4e-37 spoVIF S Stage VI sporulation protein F
EKBHDFBE_01139 1.4e-54 yjcA S Protein of unknown function (DUF1360)
EKBHDFBE_01140 3.4e-51 cotV S Spore Coat Protein X and V domain
EKBHDFBE_01141 4.8e-27 cotW
EKBHDFBE_01142 4.4e-75 cotX S Spore Coat Protein X and V domain
EKBHDFBE_01143 6.5e-92 cotY S Spore coat protein Z
EKBHDFBE_01144 5.3e-80 cotZ S Spore coat protein
EKBHDFBE_01145 2.3e-78 yjbX S Spore coat protein
EKBHDFBE_01146 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
EKBHDFBE_01147 9.9e-141 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
EKBHDFBE_01148 2.5e-178 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EKBHDFBE_01149 4.9e-134 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
EKBHDFBE_01150 2.1e-28 thiS H Thiamine biosynthesis
EKBHDFBE_01151 1.8e-198 thiO 1.4.3.19 E Glycine oxidase
EKBHDFBE_01152 8.9e-102 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
EKBHDFBE_01153 1.2e-131 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EKBHDFBE_01154 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EKBHDFBE_01155 1e-136 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
EKBHDFBE_01156 2e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EKBHDFBE_01157 2e-149 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EKBHDFBE_01158 1.6e-106 yjbM 2.7.6.5 S GTP pyrophosphokinase
EKBHDFBE_01159 1.1e-59 yjbL S Belongs to the UPF0738 family
EKBHDFBE_01160 1.3e-91 yjbK S protein conserved in bacteria
EKBHDFBE_01161 3.9e-106 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EKBHDFBE_01162 8.4e-69 yjbI S Bacterial-like globin
EKBHDFBE_01163 6.8e-167 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
EKBHDFBE_01164 1.6e-18
EKBHDFBE_01165 0.0 pepF E oligoendopeptidase F
EKBHDFBE_01166 6.6e-199 yjbF S Competence protein
EKBHDFBE_01167 8.6e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EKBHDFBE_01168 8.9e-108 yjbE P Integral membrane protein TerC family
EKBHDFBE_01169 7.8e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EKBHDFBE_01170 2.1e-100 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EKBHDFBE_01171 1.4e-220 S Putative glycosyl hydrolase domain
EKBHDFBE_01172 9.7e-169 oppF E Belongs to the ABC transporter superfamily
EKBHDFBE_01173 5.8e-197 oppD P Belongs to the ABC transporter superfamily
EKBHDFBE_01174 4.6e-163 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKBHDFBE_01175 2.3e-165 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKBHDFBE_01176 0.0 oppA E ABC transporter substrate-binding protein
EKBHDFBE_01177 7.5e-183 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
EKBHDFBE_01178 4.2e-146 yjbA S Belongs to the UPF0736 family
EKBHDFBE_01179 1.8e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKBHDFBE_01180 2.4e-170 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKBHDFBE_01181 0.0 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
EKBHDFBE_01182 3.1e-181 appF E Belongs to the ABC transporter superfamily
EKBHDFBE_01183 1.9e-178 appD P Belongs to the ABC transporter superfamily
EKBHDFBE_01184 4.4e-138 yjaZ O Zn-dependent protease
EKBHDFBE_01185 6.4e-232 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EKBHDFBE_01186 4e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EKBHDFBE_01187 7.4e-14 yjzB
EKBHDFBE_01188 7.2e-26 comZ S ComZ
EKBHDFBE_01189 2.2e-162 med S Transcriptional activator protein med
EKBHDFBE_01190 7.2e-98 yjaV
EKBHDFBE_01191 1.2e-132 yjaU I carboxylic ester hydrolase activity
EKBHDFBE_01192 4.7e-22 yjzD S Protein of unknown function (DUF2929)
EKBHDFBE_01193 1.6e-27 yjzC S YjzC-like protein
EKBHDFBE_01194 4.1e-170 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EKBHDFBE_01195 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
EKBHDFBE_01196 1e-193 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
EKBHDFBE_01197 8.6e-207 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
EKBHDFBE_01198 1.1e-128 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
EKBHDFBE_01199 2e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EKBHDFBE_01200 1.4e-192 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EKBHDFBE_01201 7.6e-89 norB G Major Facilitator Superfamily
EKBHDFBE_01202 3.6e-263 yitY C D-arabinono-1,4-lactone oxidase
EKBHDFBE_01203 2.5e-71 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
EKBHDFBE_01204 6.1e-51 yitW S metal-sulfur cluster biosynthetic enzyme
EKBHDFBE_01205 3.8e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
EKBHDFBE_01206 1.7e-148 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
EKBHDFBE_01208 7.4e-26 S Protein of unknown function (DUF3813)
EKBHDFBE_01209 2.1e-79 ipi S Intracellular proteinase inhibitor
EKBHDFBE_01210 7.3e-147 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
EKBHDFBE_01211 1.8e-153 yitS S protein conserved in bacteria
EKBHDFBE_01213 8.4e-232 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
EKBHDFBE_01214 2.3e-229 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
EKBHDFBE_01215 1.6e-145 yufN S ABC transporter substrate-binding protein PnrA-like
EKBHDFBE_01216 2.8e-154 cvfB S protein conserved in bacteria
EKBHDFBE_01217 5.7e-59 yajQ S Belongs to the UPF0234 family
EKBHDFBE_01218 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
EKBHDFBE_01219 7.8e-76 yjcF S Acetyltransferase (GNAT) domain
EKBHDFBE_01220 8.3e-71 mcbG S Pentapeptide repeats (9 copies)
EKBHDFBE_01221 1e-188 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EKBHDFBE_01222 4.6e-74 argO S Lysine exporter protein LysE YggA
EKBHDFBE_01223 9.1e-79 yisT S DinB family
EKBHDFBE_01224 1.5e-154 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
EKBHDFBE_01225 2.5e-141 purR K helix_turn _helix lactose operon repressor
EKBHDFBE_01226 1.6e-157 yisR K Transcriptional regulator
EKBHDFBE_01227 5.9e-242 yisQ V Mate efflux family protein
EKBHDFBE_01228 2.6e-116 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
EKBHDFBE_01229 0.0 asnO 6.3.5.4 E Asparagine synthase
EKBHDFBE_01230 6.5e-88 yisN S Protein of unknown function (DUF2777)
EKBHDFBE_01231 0.0 wprA O Belongs to the peptidase S8 family
EKBHDFBE_01232 1.6e-58 yisL S UPF0344 protein
EKBHDFBE_01233 1.2e-163 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
EKBHDFBE_01234 1.5e-08 yisI S Spo0E like sporulation regulatory protein
EKBHDFBE_01235 3.1e-33 gerPA S Spore germination protein
EKBHDFBE_01236 1.3e-32 gerPB S cell differentiation
EKBHDFBE_01237 1.5e-80 gerPC S Spore germination protein
EKBHDFBE_01238 2.6e-22 gerPD S Spore germination protein
EKBHDFBE_01239 2.1e-59 gerPE S Spore germination protein GerPE
EKBHDFBE_01240 1.9e-30 gerPF S Spore germination protein gerPA/gerPF
EKBHDFBE_01241 3.2e-49 yisB V COG1403 Restriction endonuclease
EKBHDFBE_01242 0.0 sbcC L COG0419 ATPase involved in DNA repair
EKBHDFBE_01243 1.5e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EKBHDFBE_01244 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
EKBHDFBE_01245 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
EKBHDFBE_01246 7.9e-118 ydfS S Protein of unknown function (DUF421)
EKBHDFBE_01247 7.9e-83 yhjR S Rubrerythrin
EKBHDFBE_01248 3.2e-107 K QacR-like protein, C-terminal region
EKBHDFBE_01249 1.1e-204 blt EGP Major facilitator Superfamily
EKBHDFBE_01250 1.3e-199 abrB S membrane
EKBHDFBE_01251 1.4e-92 yhjH K helix_turn_helix multiple antibiotic resistance protein
EKBHDFBE_01252 8.9e-265 yhjG CH FAD binding domain
EKBHDFBE_01253 3.2e-89 sipV 3.4.21.89 U Belongs to the peptidase S26 family
EKBHDFBE_01254 1.1e-104 yhjE S SNARE associated Golgi protein
EKBHDFBE_01255 1e-57 yhjD
EKBHDFBE_01256 1.5e-26 yhjC S Protein of unknown function (DUF3311)
EKBHDFBE_01257 6.3e-263 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EKBHDFBE_01258 1.4e-47 S Belongs to the UPF0145 family
EKBHDFBE_01259 4.5e-42 yhjA S Excalibur calcium-binding domain
EKBHDFBE_01260 1.5e-121 yrpD S Domain of unknown function, YrpD
EKBHDFBE_01261 1.7e-168 els S Acetyltransferase, GNAT family
EKBHDFBE_01262 7.6e-56 frataxin S Domain of unknown function (DU1801)
EKBHDFBE_01263 1.6e-108 comK K Competence transcription factor
EKBHDFBE_01264 1.5e-30 yhzC S IDEAL
EKBHDFBE_01265 1.4e-158 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKBHDFBE_01266 2e-288 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
EKBHDFBE_01267 6.2e-214 hemAT NT chemotaxis protein
EKBHDFBE_01268 4e-85 bioY S BioY family
EKBHDFBE_01269 4e-262 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
EKBHDFBE_01270 2.5e-192 vraB 2.3.1.9 I Belongs to the thiolase family
EKBHDFBE_01271 9.2e-101 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
EKBHDFBE_01272 2.9e-127 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
EKBHDFBE_01273 2.9e-202 aprE 3.4.21.62 O Belongs to the peptidase S8 family
EKBHDFBE_01274 4.6e-230 yhfN 3.4.24.84 O Peptidase M48
EKBHDFBE_01275 1.8e-63 yhfM
EKBHDFBE_01276 4.7e-293 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
EKBHDFBE_01277 8.2e-106 yhfK GM NmrA-like family
EKBHDFBE_01278 5.9e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
EKBHDFBE_01279 4e-133 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
EKBHDFBE_01280 6.6e-224 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EKBHDFBE_01281 6.4e-193 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
EKBHDFBE_01283 3.9e-176 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EKBHDFBE_01285 8.7e-291 yhgE S YhgE Pip N-terminal domain protein
EKBHDFBE_01286 6.6e-99 yhgD K Transcriptional regulator
EKBHDFBE_01287 3.3e-272 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EKBHDFBE_01288 4.4e-177 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
EKBHDFBE_01289 3.5e-197 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EKBHDFBE_01290 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EKBHDFBE_01291 1.6e-88 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
EKBHDFBE_01292 8.7e-238 yhfA C membrane
EKBHDFBE_01293 2e-214 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EKBHDFBE_01294 1.4e-119 ecsC S EcsC protein family
EKBHDFBE_01295 1.3e-216 ecsB U ABC transporter
EKBHDFBE_01296 8.2e-134 ecsA V transporter (ATP-binding protein)
EKBHDFBE_01297 8.9e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
EKBHDFBE_01298 3.4e-197 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EKBHDFBE_01299 4.6e-75 trpP S Tryptophan transporter TrpP
EKBHDFBE_01300 7.4e-17
EKBHDFBE_01301 4.3e-40 yhaH S YtxH-like protein
EKBHDFBE_01302 8e-111 hpr K Negative regulator of protease production and sporulation
EKBHDFBE_01303 1.7e-54 yhaI S Protein of unknown function (DUF1878)
EKBHDFBE_01304 2.9e-93 yhaK S Putative zincin peptidase
EKBHDFBE_01305 3.2e-142 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EKBHDFBE_01306 3.9e-31 yhaL S Sporulation protein YhaL
EKBHDFBE_01307 1.6e-174 yhaM L Shows a 3'-5' exoribonuclease activity
EKBHDFBE_01308 0.0 yhaN L AAA domain
EKBHDFBE_01309 2.6e-230 yhaO L DNA repair exonuclease
EKBHDFBE_01310 2.5e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
EKBHDFBE_01311 5.9e-163 yhaQ S ABC transporter, ATP-binding protein
EKBHDFBE_01312 7.9e-14 S YhzD-like protein
EKBHDFBE_01313 4.6e-132 yhaR 5.3.3.18 I enoyl-CoA hydratase
EKBHDFBE_01315 5.5e-86 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
EKBHDFBE_01316 6.5e-205 yhaU P COG0475 Kef-type K transport systems, membrane components
EKBHDFBE_01317 4.7e-244 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
EKBHDFBE_01318 3.3e-291 hemZ H coproporphyrinogen III oxidase
EKBHDFBE_01319 2.4e-153 yhaX S haloacid dehalogenase-like hydrolase
EKBHDFBE_01320 4.8e-52 yheA S Belongs to the UPF0342 family
EKBHDFBE_01321 3.8e-199 yheB S Belongs to the UPF0754 family
EKBHDFBE_01322 8.7e-201 yheC HJ YheC/D like ATP-grasp
EKBHDFBE_01323 3.7e-249 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
EKBHDFBE_01324 4.8e-36 yheE S Family of unknown function (DUF5342)
EKBHDFBE_01325 1.1e-27 sspB S spore protein
EKBHDFBE_01327 7.1e-99 yheG GM NAD(P)H-binding
EKBHDFBE_01328 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
EKBHDFBE_01329 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
EKBHDFBE_01330 4.4e-83 T universal stress protein
EKBHDFBE_01331 6.3e-91 ymcC S Membrane
EKBHDFBE_01332 2.2e-82 pksA K Transcriptional regulator
EKBHDFBE_01333 1.6e-149 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
EKBHDFBE_01334 1.8e-148 yheN G deacetylase
EKBHDFBE_01335 1.6e-134 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
EKBHDFBE_01336 1.9e-198 yhdY M Mechanosensitive ion channel
EKBHDFBE_01338 2.1e-123 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
EKBHDFBE_01339 9.9e-54 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EKBHDFBE_01340 2.9e-52 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EKBHDFBE_01341 1.5e-245 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
EKBHDFBE_01342 6.8e-226 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EKBHDFBE_01343 3.2e-217 yhdR 2.6.1.1 E Aminotransferase
EKBHDFBE_01344 2.4e-69 cueR K transcriptional
EKBHDFBE_01345 2.6e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
EKBHDFBE_01346 2.9e-105 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EKBHDFBE_01347 2.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
EKBHDFBE_01348 1.6e-194 yhdL S Sigma factor regulator N-terminal
EKBHDFBE_01349 1.2e-43 yhdK S Sigma-M inhibitor protein
EKBHDFBE_01350 1.5e-207 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EKBHDFBE_01351 9.7e-245 yhdG E amino acid
EKBHDFBE_01352 3.1e-156 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKBHDFBE_01353 5.9e-197 citA 2.3.3.1 C Belongs to the citrate synthase family
EKBHDFBE_01354 3.1e-156 citR K Transcriptional regulator
EKBHDFBE_01355 1.8e-129 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
EKBHDFBE_01356 2.6e-250 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
EKBHDFBE_01357 4.3e-269 ycgB S Stage V sporulation protein R
EKBHDFBE_01358 3.3e-246 ygxB M Conserved TM helix
EKBHDFBE_01359 4.4e-71 nsrR K Transcriptional regulator
EKBHDFBE_01360 4.5e-221 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
EKBHDFBE_01361 3.7e-51 yhdC S Protein of unknown function (DUF3889)
EKBHDFBE_01362 6.1e-38 yhdB S YhdB-like protein
EKBHDFBE_01363 1e-82 azr 1.7.1.6 S NADPH-dependent FMN reductase
EKBHDFBE_01364 7.4e-107 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EKBHDFBE_01365 4.4e-96 yhcY 2.7.13.3 T Histidine kinase
EKBHDFBE_01366 9.9e-46 yhcY 2.7.13.3 T Histidine kinase
EKBHDFBE_01367 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
EKBHDFBE_01368 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EKBHDFBE_01369 3.2e-286 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EKBHDFBE_01370 1.7e-151 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
EKBHDFBE_01371 9.2e-101 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EKBHDFBE_01372 1.9e-253 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EKBHDFBE_01373 6.8e-300 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EKBHDFBE_01374 1.8e-122 yhcW 5.4.2.6 S hydrolase
EKBHDFBE_01375 1.7e-67 yhcV S COG0517 FOG CBS domain
EKBHDFBE_01376 5.6e-65 yhcU S Family of unknown function (DUF5365)
EKBHDFBE_01377 1.3e-160 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EKBHDFBE_01378 9.5e-101 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
EKBHDFBE_01379 2.8e-301 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
EKBHDFBE_01380 1.4e-113 yhcQ M Spore coat protein
EKBHDFBE_01381 1e-154 yhcP
EKBHDFBE_01382 5.3e-90 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EKBHDFBE_01389 1.3e-146 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EKBHDFBE_01390 1e-153 K Helix-turn-helix XRE-family like proteins
EKBHDFBE_01391 7.9e-121 ydhB S membrane transporter protein
EKBHDFBE_01392 1.1e-77 bltD 2.3.1.57 K FR47-like protein
EKBHDFBE_01393 2.2e-140 bltR K helix_turn_helix, mercury resistance
EKBHDFBE_01394 3.9e-143 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EKBHDFBE_01395 1.3e-105 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
EKBHDFBE_01396 7.4e-105 S Alpha/beta hydrolase family
EKBHDFBE_01397 4e-166 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Isocitrate/isopropylmalate dehydrogenase
EKBHDFBE_01398 4e-111 ydhC K FCD
EKBHDFBE_01399 1.2e-216 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EKBHDFBE_01401 6.1e-244 pbpE V Beta-lactamase
EKBHDFBE_01403 2.1e-97 ydhK M Protein of unknown function (DUF1541)
EKBHDFBE_01404 1.1e-190 pbuE EGP Major facilitator Superfamily
EKBHDFBE_01405 2.6e-129 ydhQ K UTRA
EKBHDFBE_01406 4.3e-113 K FCD
EKBHDFBE_01407 4.3e-209 yeaN P COG2807 Cyanate permease
EKBHDFBE_01408 3.2e-47 sugE P Small Multidrug Resistance protein
EKBHDFBE_01409 3e-48 ykkC P Small Multidrug Resistance protein
EKBHDFBE_01410 6.7e-99 yvdT K Transcriptional regulator
EKBHDFBE_01411 8.2e-293 yveA E amino acid
EKBHDFBE_01412 3.7e-162 ydhU P Catalase
EKBHDFBE_01413 3.5e-82 yndB S Activator of Hsp90 ATPase homolog 1-like protein
EKBHDFBE_01414 7.3e-178 yhfP 1.1.1.1 C Quinone oxidoreductase
EKBHDFBE_01415 6.8e-246 iolT EGP Major facilitator Superfamily
EKBHDFBE_01418 3.2e-29 csfB S Inhibitor of sigma-G Gin
EKBHDFBE_01419 9.8e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
EKBHDFBE_01420 4e-177 yaaN P Belongs to the TelA family
EKBHDFBE_01421 7.3e-256 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
EKBHDFBE_01422 5.1e-108 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EKBHDFBE_01423 9.7e-55 yaaQ S protein conserved in bacteria
EKBHDFBE_01424 7.1e-69 yaaR S protein conserved in bacteria
EKBHDFBE_01425 5e-179 holB 2.7.7.7 L DNA polymerase III
EKBHDFBE_01426 1.2e-146 yaaT S stage 0 sporulation protein
EKBHDFBE_01427 1.8e-41 yabA L Involved in initiation control of chromosome replication
EKBHDFBE_01428 3.3e-135 yabB 2.1.1.223 S Conserved hypothetical protein 95
EKBHDFBE_01429 8.8e-47 yazA L endonuclease containing a URI domain
EKBHDFBE_01430 3.1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EKBHDFBE_01431 5.6e-43 abrB K COG2002 Regulators of stationary sporulation gene expression
EKBHDFBE_01432 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EKBHDFBE_01433 1.2e-140 tatD L hydrolase, TatD
EKBHDFBE_01434 2e-223 rpfB GH23 T protein conserved in bacteria
EKBHDFBE_01435 3.9e-96 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EKBHDFBE_01436 6.2e-157 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EKBHDFBE_01437 3.2e-145 yabG S peptidase
EKBHDFBE_01438 4.5e-39 veg S protein conserved in bacteria
EKBHDFBE_01439 3.7e-27 sspF S DNA topological change
EKBHDFBE_01440 1.7e-159 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EKBHDFBE_01441 1.7e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
EKBHDFBE_01442 1.5e-62 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
EKBHDFBE_01443 1e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
EKBHDFBE_01444 4.4e-250 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EKBHDFBE_01445 1.8e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EKBHDFBE_01446 8e-103 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EKBHDFBE_01447 8.8e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EKBHDFBE_01448 6.8e-39 yabK S Peptide ABC transporter permease
EKBHDFBE_01449 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EKBHDFBE_01450 2e-89 spoVT K stage V sporulation protein
EKBHDFBE_01451 8.9e-271 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EKBHDFBE_01452 5.9e-269 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
EKBHDFBE_01453 1.2e-36 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
EKBHDFBE_01454 3.3e-49 yabP S Sporulation protein YabP
EKBHDFBE_01455 3e-100 yabQ S spore cortex biosynthesis protein
EKBHDFBE_01456 4.5e-56 divIC D Septum formation initiator
EKBHDFBE_01457 4.3e-62 yabR J RNA binding protein (contains ribosomal protein S1 domain)
EKBHDFBE_01460 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
EKBHDFBE_01461 1.5e-127 yabS S protein containing a von Willebrand factor type A (vWA) domain
EKBHDFBE_01462 5.6e-178 KLT serine threonine protein kinase
EKBHDFBE_01463 5.2e-262 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EKBHDFBE_01464 2.8e-91 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
EKBHDFBE_01465 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EKBHDFBE_01466 6e-137 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EKBHDFBE_01467 3.9e-159 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EKBHDFBE_01468 9.7e-150 yacD 5.2.1.8 O peptidyl-prolyl isomerase
EKBHDFBE_01469 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EKBHDFBE_01470 4.4e-261 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EKBHDFBE_01471 1.8e-104 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
EKBHDFBE_01472 6.7e-148 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
EKBHDFBE_01473 4.8e-154 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EKBHDFBE_01474 1.3e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EKBHDFBE_01475 1.9e-86 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EKBHDFBE_01476 5.3e-28 yazB K transcriptional
EKBHDFBE_01477 3.9e-179 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EKBHDFBE_01478 1.3e-284 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
EKBHDFBE_01479 2e-56 2.3.1.183 M Acetyltransferase (GNAT) domain
EKBHDFBE_01487 5.2e-56 ydcK S Belongs to the SprT family
EKBHDFBE_01488 2.2e-14
EKBHDFBE_01489 0.0 yhgF K COG2183 Transcriptional accessory protein
EKBHDFBE_01490 6.5e-105 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
EKBHDFBE_01491 1.2e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EKBHDFBE_01492 6.6e-84 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
EKBHDFBE_01493 5e-51 rsbV T Belongs to the anti-sigma-factor antagonist family
EKBHDFBE_01494 1.5e-186 rsbU 3.1.3.3 KT phosphatase
EKBHDFBE_01495 1.3e-66 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
EKBHDFBE_01496 5.2e-57 rsbS T antagonist
EKBHDFBE_01497 1.5e-136 rsbR T Positive regulator of sigma-B
EKBHDFBE_01498 1.9e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
EKBHDFBE_01499 3.6e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
EKBHDFBE_01500 2.8e-213 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EKBHDFBE_01501 7.8e-180 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
EKBHDFBE_01502 1.6e-53 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EKBHDFBE_01503 9.3e-104 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
EKBHDFBE_01504 1.2e-253 ydbT S Membrane
EKBHDFBE_01505 1.6e-69 ydbS S Bacterial PH domain
EKBHDFBE_01506 7.6e-264 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EKBHDFBE_01507 5.7e-250 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EKBHDFBE_01508 2.5e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EKBHDFBE_01509 1.1e-55 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
EKBHDFBE_01510 4.9e-125 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EKBHDFBE_01511 1.2e-09 S Fur-regulated basic protein A
EKBHDFBE_01512 2.2e-11 S Fur-regulated basic protein B
EKBHDFBE_01513 4.5e-200 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
EKBHDFBE_01514 2.7e-52 ydbL
EKBHDFBE_01515 3.4e-127 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EKBHDFBE_01516 1.2e-169 ydbJ V ABC transporter, ATP-binding protein
EKBHDFBE_01517 3.2e-176 ydbI S AI-2E family transporter
EKBHDFBE_01518 2.5e-223 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EKBHDFBE_01519 1.4e-113 dctR T COG4565 Response regulator of citrate malate metabolism
EKBHDFBE_01520 3.8e-293 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
EKBHDFBE_01521 2.9e-193 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
EKBHDFBE_01522 3.3e-152 ydbD P Catalase
EKBHDFBE_01523 3.9e-57 ydbC S Domain of unknown function (DUF4937
EKBHDFBE_01524 3.1e-62 ydbB G Cupin domain
EKBHDFBE_01526 3.6e-135 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
EKBHDFBE_01527 3.8e-52 yvaE P Small Multidrug Resistance protein
EKBHDFBE_01528 2e-73 yvaD S Family of unknown function (DUF5360)
EKBHDFBE_01529 4.2e-33 ydaT
EKBHDFBE_01531 8.6e-224 mntH P H( )-stimulated, divalent metal cation uptake system
EKBHDFBE_01532 1.2e-39
EKBHDFBE_01534 3.5e-60 K acetyltransferase
EKBHDFBE_01535 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
EKBHDFBE_01536 4.2e-69 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
EKBHDFBE_01537 0.0 ydaO E amino acid
EKBHDFBE_01538 0.0 ydaN S Bacterial cellulose synthase subunit
EKBHDFBE_01539 4.8e-235 ydaM M Glycosyl transferase family group 2
EKBHDFBE_01540 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
EKBHDFBE_01541 4.9e-143 ydaK T Diguanylate cyclase, GGDEF domain
EKBHDFBE_01542 3.8e-188 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
EKBHDFBE_01543 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EKBHDFBE_01544 7.2e-74 lrpC K Transcriptional regulator
EKBHDFBE_01545 3.6e-45 ydzA EGP Major facilitator Superfamily
EKBHDFBE_01546 6.2e-135 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
EKBHDFBE_01547 3.7e-75 ydaG 1.4.3.5 S general stress protein
EKBHDFBE_01548 1.2e-106 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EKBHDFBE_01549 7.3e-94 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
EKBHDFBE_01550 5.7e-155 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKBHDFBE_01551 6.3e-282 ydaB IQ acyl-CoA ligase
EKBHDFBE_01552 0.0 mtlR K transcriptional regulator, MtlR
EKBHDFBE_01553 1.7e-165 ydhF S Oxidoreductase
EKBHDFBE_01554 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
EKBHDFBE_01555 3.6e-54 yczJ S biosynthesis
EKBHDFBE_01557 1.6e-109 ycsK E anatomical structure formation involved in morphogenesis
EKBHDFBE_01558 3.9e-126 kipR K Transcriptional regulator
EKBHDFBE_01559 5.8e-175 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
EKBHDFBE_01560 7.5e-132 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
EKBHDFBE_01561 1.9e-141 ycsI S Belongs to the D-glutamate cyclase family
EKBHDFBE_01562 2.5e-209 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
EKBHDFBE_01563 6e-132 ycsF S Belongs to the UPF0271 (lamB) family
EKBHDFBE_01564 1.1e-135 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
EKBHDFBE_01566 4.6e-59 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
EKBHDFBE_01567 5.8e-200 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
EKBHDFBE_01568 5.7e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
EKBHDFBE_01569 3.2e-251 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
EKBHDFBE_01570 3.2e-53
EKBHDFBE_01571 8e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
EKBHDFBE_01572 3.8e-293 ycnJ P protein, homolog of Cu resistance protein CopC
EKBHDFBE_01573 5.6e-96 ycnI S protein conserved in bacteria
EKBHDFBE_01574 3.6e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKBHDFBE_01575 9.8e-147 glcU U Glucose uptake
EKBHDFBE_01576 1.4e-259 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EKBHDFBE_01577 2.5e-218 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EKBHDFBE_01578 7.4e-253 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EKBHDFBE_01579 1.4e-50 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
EKBHDFBE_01580 5.1e-44 ycnE S Monooxygenase
EKBHDFBE_01581 2.4e-133 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
EKBHDFBE_01582 2.1e-149 ycnC K Transcriptional regulator
EKBHDFBE_01583 6.4e-244 ycnB EGP Major facilitator Superfamily
EKBHDFBE_01584 3.3e-172 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
EKBHDFBE_01585 4.9e-134 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
EKBHDFBE_01586 1.3e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKBHDFBE_01587 1.1e-162 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKBHDFBE_01588 4.5e-247 lysC 2.7.2.4 E Belongs to the aspartokinase family
EKBHDFBE_01591 7.5e-78 S aspartate phosphatase
EKBHDFBE_01592 4e-254 T PhoQ Sensor
EKBHDFBE_01593 2.9e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKBHDFBE_01594 3.8e-236 yclI V ABC transporter (permease) YclI
EKBHDFBE_01595 1.2e-118 yclH P ABC transporter
EKBHDFBE_01596 1.1e-237 yxeQ S MmgE/PrpD family
EKBHDFBE_01597 5.2e-212 yxeP 3.5.1.47 E hydrolase activity
EKBHDFBE_01598 1.9e-130 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
EKBHDFBE_01599 3.8e-114 yxeN P COG0765 ABC-type amino acid transport system, permease component
EKBHDFBE_01600 4e-139 yxeM M Belongs to the bacterial solute-binding protein 3 family
EKBHDFBE_01601 3.1e-89 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EKBHDFBE_01602 5.7e-247 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKBHDFBE_01603 2.4e-190 gerKB F Spore germination protein
EKBHDFBE_01604 1.6e-227 gerKC S spore germination
EKBHDFBE_01605 1e-282 gerKA EG Spore germination protein
EKBHDFBE_01607 5.2e-272 yclG M Pectate lyase superfamily protein
EKBHDFBE_01608 1.3e-263 dtpT E amino acid peptide transporter
EKBHDFBE_01609 6.5e-73 yclD
EKBHDFBE_01610 9.1e-36 bsdD 4.1.1.61 S response to toxic substance
EKBHDFBE_01611 2.3e-278 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
EKBHDFBE_01612 3.5e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
EKBHDFBE_01613 4.9e-154 bsdA K LysR substrate binding domain
EKBHDFBE_01614 1.6e-143 tcyA ET Belongs to the bacterial solute-binding protein 3 family
EKBHDFBE_01615 1.7e-117 tcyB P COG0765 ABC-type amino acid transport system, permease component
EKBHDFBE_01616 7.2e-130 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
EKBHDFBE_01617 3.6e-106 yczE S membrane
EKBHDFBE_01618 3.9e-119 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
EKBHDFBE_01619 1.1e-245 bamJ E Aminotransferase class I and II
EKBHDFBE_01620 6.6e-136 srfAD Q thioesterase
EKBHDFBE_01621 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
EKBHDFBE_01622 1.9e-231 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKBHDFBE_01624 1.1e-175 yaaC S YaaC-like Protein
EKBHDFBE_01625 3e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
EKBHDFBE_01626 1.2e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EKBHDFBE_01627 6.3e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EKBHDFBE_01628 2.6e-106 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EKBHDFBE_01629 2.3e-221 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EKBHDFBE_01630 1e-196 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
EKBHDFBE_01632 2.2e-119 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
EKBHDFBE_01633 4.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
EKBHDFBE_01634 2.2e-211 yaaH M Glycoside Hydrolase Family
EKBHDFBE_01635 1.5e-95 yaaI Q COG1335 Amidases related to nicotinamidase
EKBHDFBE_01636 1.2e-82 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EKBHDFBE_01637 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EKBHDFBE_01638 1.3e-38 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EKBHDFBE_01639 4.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EKBHDFBE_01640 8.7e-31 yaaL S Protein of unknown function (DUF2508)
EKBHDFBE_01641 1.4e-35 bofA S Sigma-K factor-processing regulatory protein BofA
EKBHDFBE_01644 9.5e-09 K Transcriptional regulator
EKBHDFBE_01645 1.2e-10 lexA 3.4.21.88 KT domain protein
EKBHDFBE_01648 8.9e-12 K Helix-turn-helix XRE-family like proteins
EKBHDFBE_01656 3.4e-13
EKBHDFBE_01657 8.9e-61
EKBHDFBE_01661 9.4e-43 S transposition, DNA-mediated
EKBHDFBE_01662 4.2e-115 S HTH-like domain
EKBHDFBE_01665 1.4e-09 K Transcriptional regulator
EKBHDFBE_01666 5.6e-14 K Transcriptional regulator
EKBHDFBE_01667 3.6e-158 S Domain of unknown function (DUF5068)
EKBHDFBE_01668 4.2e-32
EKBHDFBE_01669 2.5e-48 repB L Initiator Replication protein
EKBHDFBE_01676 2.7e-17 K sigma factor activity
EKBHDFBE_01677 1.9e-144 L Molecular Function DNA binding, Biological Process DNA recombination
EKBHDFBE_01678 2.9e-54 L transposase activity
EKBHDFBE_01680 3.6e-08
EKBHDFBE_01682 1.3e-09 yddH M NlpC P60 family protein
EKBHDFBE_01685 6.2e-32 pilT NU Tfp pilus assembly protein pilus retraction ATPase PilT
EKBHDFBE_01691 1.9e-07
EKBHDFBE_01696 3.7e-21 K Transcriptional regulator
EKBHDFBE_01699 5.3e-36 L DnaD domain protein
EKBHDFBE_01700 2.4e-08 S CAAX protease self-immunity
EKBHDFBE_01702 7.7e-55 ypuA S Protein of unknown function (DUF1002)
EKBHDFBE_01711 3.2e-07 ropB K Helix-turn-helix domain
EKBHDFBE_01712 9.5e-08 ssb L single-stranded DNA binding
EKBHDFBE_01713 3.9e-17 S mRNA catabolic process
EKBHDFBE_01714 7.8e-54 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
EKBHDFBE_01715 4.8e-150 M Psort location Cellwall, score
EKBHDFBE_01719 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EKBHDFBE_01720 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EKBHDFBE_01721 3.6e-38 yaaB S Domain of unknown function (DUF370)
EKBHDFBE_01722 3e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EKBHDFBE_01723 6.8e-33 yaaA S S4 domain
EKBHDFBE_01724 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EKBHDFBE_01725 7.3e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EKBHDFBE_01726 1.2e-50 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EKBHDFBE_01727 1.2e-138 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EKBHDFBE_01728 4e-105 jag S single-stranded nucleic acid binding R3H
EKBHDFBE_01729 4.7e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EKBHDFBE_01730 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EKBHDFBE_01731 8.8e-125 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
EKBHDFBE_01732 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
EKBHDFBE_01733 1.5e-133 soj D COG1192 ATPases involved in chromosome partitioning
EKBHDFBE_01734 4.8e-146 spo0J K Belongs to the ParB family
EKBHDFBE_01735 1.7e-108 yyaC S Sporulation protein YyaC
EKBHDFBE_01736 3.4e-47 4.2.1.103 K FR47-like protein
EKBHDFBE_01737 3.1e-168 yyaD S Membrane
EKBHDFBE_01738 5e-33 yyzM S protein conserved in bacteria
EKBHDFBE_01739 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EKBHDFBE_01740 1.6e-197 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EKBHDFBE_01741 1e-44 rpsF J Binds together with S18 to 16S ribosomal RNA
EKBHDFBE_01742 1.6e-75 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EKBHDFBE_01743 1.9e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EKBHDFBE_01744 1.4e-96 adaA 3.2.2.21 K Transcriptional regulator
EKBHDFBE_01745 4.1e-87 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EKBHDFBE_01746 1.2e-137 xth 3.1.11.2 L exodeoxyribonuclease III
EKBHDFBE_01747 1.5e-169 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
EKBHDFBE_01748 4.1e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EKBHDFBE_01749 3.8e-179 ydjK G Sugar (and other) transporter
EKBHDFBE_01750 8.8e-151 yyaK S CAAX protease self-immunity
EKBHDFBE_01751 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
EKBHDFBE_01752 9e-22 yyaL O Highly conserved protein containing a thioredoxin domain
EKBHDFBE_01753 1.4e-31
EKBHDFBE_01755 8.1e-21
EKBHDFBE_01756 1.9e-38 immA E Pfam:DUF955
EKBHDFBE_01757 3e-31 yvaO K Transcriptional
EKBHDFBE_01758 4.6e-09
EKBHDFBE_01759 4.1e-24
EKBHDFBE_01761 4.2e-38 S Bacterial protein of unknown function (DUF961)
EKBHDFBE_01762 3.5e-226 ydcQ D Ftsk spoiiie family protein
EKBHDFBE_01763 3.1e-160 nicK L Replication initiation factor
EKBHDFBE_01764 4.9e-16 S Domain of Unknown Function with PDB structure (DUF3850)
EKBHDFBE_01769 3e-129 yddB S Conjugative transposon protein TcpC
EKBHDFBE_01770 5.1e-24 yddC
EKBHDFBE_01771 1.8e-74 yddD S TcpE family
EKBHDFBE_01772 0.0 yddE S AAA-like domain
EKBHDFBE_01773 1.2e-33 S Domain of unknown function (DUF1874)
EKBHDFBE_01774 4.8e-212 yddG S maturation of SSU-rRNA
EKBHDFBE_01775 6.5e-158 yddH CBM50 M Lysozyme-like
EKBHDFBE_01776 4.7e-56 yddI
EKBHDFBE_01777 3.7e-42 S Domain of unknown function with cystatin-like fold (DUF4467)
EKBHDFBE_01779 3.8e-13 S Domain of unknown function (DUF4367)
EKBHDFBE_01780 6.5e-125 S response regulator aspartate phosphatase
EKBHDFBE_01798 1.6e-275 C Na+/H+ antiporter family
EKBHDFBE_01799 8e-123 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
EKBHDFBE_01800 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EKBHDFBE_01801 5.5e-245 ygaK C Berberine and berberine like
EKBHDFBE_01803 2.2e-230 oppA5 E PFAM extracellular solute-binding protein family 5
EKBHDFBE_01804 5.9e-145 appB P Binding-protein-dependent transport system inner membrane component
EKBHDFBE_01805 4.1e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKBHDFBE_01806 1.9e-133 oppD3 P Belongs to the ABC transporter superfamily
EKBHDFBE_01807 1.6e-129 oppF3 E Belongs to the ABC transporter superfamily
EKBHDFBE_01808 6.4e-284 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
EKBHDFBE_01809 8.3e-176 S Amidohydrolase
EKBHDFBE_01810 1.1e-133 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
EKBHDFBE_01811 2e-172 ssuA M Sulfonate ABC transporter
EKBHDFBE_01812 5.4e-142 ssuC P ABC transporter (permease)
EKBHDFBE_01813 8.8e-212 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
EKBHDFBE_01815 1.6e-39 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EKBHDFBE_01816 1.3e-76 ygaO
EKBHDFBE_01817 1.8e-22 K Transcriptional regulator
EKBHDFBE_01819 1e-105 yhzB S B3/4 domain
EKBHDFBE_01820 5.2e-220 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EKBHDFBE_01821 2.2e-168 yhbB S Putative amidase domain
EKBHDFBE_01822 3.8e-84 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EKBHDFBE_01823 3.7e-103 yhbD K Protein of unknown function (DUF4004)
EKBHDFBE_01824 2.2e-59 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
EKBHDFBE_01825 1.7e-67 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
EKBHDFBE_01827 0.0 prkA T Ser protein kinase
EKBHDFBE_01828 3e-215 yhbH S Belongs to the UPF0229 family
EKBHDFBE_01829 1.2e-71 yhbI K DNA-binding transcription factor activity
EKBHDFBE_01830 1.3e-100 yhbJ V COG1566 Multidrug resistance efflux pump
EKBHDFBE_01831 1.3e-285 yhcA EGP Major facilitator Superfamily
EKBHDFBE_01832 3e-98 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
EKBHDFBE_01833 4.8e-50 yhcC
EKBHDFBE_01834 1.4e-51
EKBHDFBE_01835 3.1e-57 yhcF K Transcriptional regulator
EKBHDFBE_01836 1.1e-114 yhcG V ABC transporter, ATP-binding protein
EKBHDFBE_01837 1.9e-164 yhcH V ABC transporter, ATP-binding protein
EKBHDFBE_01838 8.8e-157 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EKBHDFBE_01839 2.9e-30 cspB K 'Cold-shock' DNA-binding domain
EKBHDFBE_01840 1.3e-127 metQ M Belongs to the nlpA lipoprotein family
EKBHDFBE_01841 7.1e-179 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
EKBHDFBE_01842 2.7e-228 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EKBHDFBE_01843 6.3e-147 S PQQ-like domain
EKBHDFBE_01844 1.6e-57 S Family of unknown function (DUF5391)
EKBHDFBE_01845 1.5e-49 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
EKBHDFBE_01846 8.2e-197 EGP Major facilitator Superfamily
EKBHDFBE_01847 2e-66 yxaI S membrane protein domain
EKBHDFBE_01848 6.9e-119 E Ring-cleavage extradiol dioxygenase
EKBHDFBE_01849 3.3e-103 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
EKBHDFBE_01850 2.8e-282 ahpF O Alkyl hydroperoxide reductase
EKBHDFBE_01851 1.6e-182 G Major royal jelly protein
EKBHDFBE_01852 7.2e-237 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
EKBHDFBE_01853 8.9e-157 K helix_turn_helix, Deoxyribose operon repressor
EKBHDFBE_01854 2.6e-72 K Integron-associated effector binding protein
EKBHDFBE_01855 9.1e-75 yjhE S Phage tail protein
EKBHDFBE_01856 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
EKBHDFBE_01857 1.5e-75 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
EKBHDFBE_01858 1.1e-142 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
EKBHDFBE_01859 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
EKBHDFBE_01860 3.3e-80 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
EKBHDFBE_01861 1.6e-167 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EKBHDFBE_01862 1e-163 S Fusaric acid resistance protein-like
EKBHDFBE_01863 8.9e-16 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
EKBHDFBE_01866 3.7e-163 rarA L atpase related to the helicase subunit of the holliday junction resolvase
EKBHDFBE_01867 1.3e-43
EKBHDFBE_01868 1.2e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EKBHDFBE_01869 1e-07 S YyzF-like protein
EKBHDFBE_01871 1.9e-206 yycP
EKBHDFBE_01872 2.7e-129 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EKBHDFBE_01873 2.5e-178 C oxidoreductases (related to aryl-alcohol dehydrogenases)
EKBHDFBE_01874 3.9e-81 yycN 2.3.1.128 K Acetyltransferase
EKBHDFBE_01876 4.4e-200 S Histidine kinase
EKBHDFBE_01877 4.5e-163 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
EKBHDFBE_01878 2.8e-252 rocE E amino acid
EKBHDFBE_01879 8.9e-231 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
EKBHDFBE_01880 1.2e-58 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
EKBHDFBE_01881 2.2e-42 sdpR K transcriptional
EKBHDFBE_01882 3.2e-254 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
EKBHDFBE_01883 1.2e-142 1.14.11.27 P peptidyl-arginine hydroxylation
EKBHDFBE_01884 1.8e-298 S ABC transporter
EKBHDFBE_01885 6.2e-200 S Major Facilitator Superfamily
EKBHDFBE_01886 5.2e-240
EKBHDFBE_01887 1e-179 2.7.7.73, 2.7.7.80 H ThiF family
EKBHDFBE_01888 3.5e-242 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
EKBHDFBE_01889 5.4e-92 K PFAM response regulator receiver
EKBHDFBE_01890 7.3e-68 S Peptidase propeptide and YPEB domain
EKBHDFBE_01891 1.4e-212 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EKBHDFBE_01892 4.8e-148 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
EKBHDFBE_01893 1.7e-148 yycI S protein conserved in bacteria
EKBHDFBE_01894 3.3e-258 yycH S protein conserved in bacteria
EKBHDFBE_01895 0.0 vicK 2.7.13.3 T Histidine kinase
EKBHDFBE_01896 3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKBHDFBE_01901 2.1e-246 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EKBHDFBE_01902 1.2e-70 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EKBHDFBE_01903 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
EKBHDFBE_01904 3.9e-27 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
EKBHDFBE_01906 1.7e-16 yycC K YycC-like protein
EKBHDFBE_01907 8e-214 M Glycosyltransferase Family 4
EKBHDFBE_01908 1e-190 S Ecdysteroid kinase
EKBHDFBE_01909 2.7e-227 S Carbamoyl-phosphate synthase L chain, ATP binding domain
EKBHDFBE_01910 1e-219 M Glycosyltransferase Family 4
EKBHDFBE_01911 2.9e-119 S GlcNAc-PI de-N-acetylase
EKBHDFBE_01912 2.6e-82 KLT COG0515 Serine threonine protein kinase
EKBHDFBE_01913 1.4e-72 rplI J binds to the 23S rRNA
EKBHDFBE_01914 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
EKBHDFBE_01915 1.5e-148 yybS S membrane
EKBHDFBE_01917 2.6e-80 cotF M Spore coat protein
EKBHDFBE_01918 1.5e-59 ydeP3 K Transcriptional regulator
EKBHDFBE_01919 8e-163 ppaC 3.6.1.1 C Inorganic pyrophosphatase
EKBHDFBE_01920 4.2e-150 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EKBHDFBE_01921 9.7e-269 sacB 2.4.1.10 GH68 M levansucrase activity
EKBHDFBE_01922 4.9e-298 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
EKBHDFBE_01923 1.5e-110 K FCD domain
EKBHDFBE_01925 9.3e-41 CP Membrane
EKBHDFBE_01927 1.2e-20 S Domain of unknown function (DUF4177)
EKBHDFBE_01928 3e-22
EKBHDFBE_01929 1.4e-16 ydcG K sequence-specific DNA binding
EKBHDFBE_01930 5e-07 KT regulator
EKBHDFBE_01931 6e-53 ypaA S Protein of unknown function (DUF1304)
EKBHDFBE_01932 2.2e-111 drgA C nitroreductase
EKBHDFBE_01933 2.3e-64 ydgJ K Winged helix DNA-binding domain
EKBHDFBE_01934 1.2e-147 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
EKBHDFBE_01935 3.4e-74 yybA 2.3.1.57 K transcriptional
EKBHDFBE_01936 2.4e-70 yjcF S Acetyltransferase (GNAT) domain
EKBHDFBE_01937 6.2e-41
EKBHDFBE_01938 3.3e-68 ynaF
EKBHDFBE_01939 2e-24 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
EKBHDFBE_01940 1.3e-53 L Recombinase
EKBHDFBE_01941 6.7e-91 thiT S Thiamine transporter protein (Thia_YuaJ)
EKBHDFBE_01942 2.5e-217 yuaG 3.4.21.72 S protein conserved in bacteria
EKBHDFBE_01943 3.7e-80 yuaF OU Membrane protein implicated in regulation of membrane protease activity
EKBHDFBE_01944 9.3e-78 yuaE S DinB superfamily
EKBHDFBE_01945 1.7e-102 yuaD S MOSC domain
EKBHDFBE_01946 2.8e-224 gbsB 1.1.1.1 C alcohol dehydrogenase
EKBHDFBE_01947 6.3e-279 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
EKBHDFBE_01948 2.4e-90 yuaC K Belongs to the GbsR family
EKBHDFBE_01949 2.8e-91 yuaB
EKBHDFBE_01950 1.1e-118 ktrA P COG0569 K transport systems, NAD-binding component
EKBHDFBE_01951 4e-145 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EKBHDFBE_01952 1.3e-210 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EKBHDFBE_01953 3.2e-110 G Cupin
EKBHDFBE_01954 4.4e-44 yjcN
EKBHDFBE_01957 3.1e-140 S Aspartate phosphatase response regulator
EKBHDFBE_01958 5.1e-14
EKBHDFBE_01960 3.4e-141 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EKBHDFBE_01961 1.7e-194 yubA S transporter activity
EKBHDFBE_01962 1.4e-178 ygjR S Oxidoreductase
EKBHDFBE_01963 1.6e-96 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
EKBHDFBE_01964 1.6e-264 mcpA NT chemotaxis protein
EKBHDFBE_01965 2e-272 mcpA NT chemotaxis protein
EKBHDFBE_01966 1.2e-269 mcpA NT chemotaxis protein
EKBHDFBE_01967 2.4e-228 mcpA NT chemotaxis protein
EKBHDFBE_01968 5.6e-135 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
EKBHDFBE_01969 1.3e-38
EKBHDFBE_01970 1.3e-185 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
EKBHDFBE_01971 7e-74 yugU S Uncharacterised protein family UPF0047
EKBHDFBE_01972 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
EKBHDFBE_01973 6.2e-230 yugS S COG1253 Hemolysins and related proteins containing CBS domains
EKBHDFBE_01974 2e-115 yugP S Zn-dependent protease
EKBHDFBE_01975 1.9e-16
EKBHDFBE_01976 7.3e-26 mstX S Membrane-integrating protein Mistic
EKBHDFBE_01977 1e-176 yugO P COG1226 Kef-type K transport systems
EKBHDFBE_01978 3.2e-68 yugN S YugN-like family
EKBHDFBE_01980 1.1e-256 pgi 5.3.1.9 G Belongs to the GPI family
EKBHDFBE_01981 6.1e-97 S NADPH-dependent FMN reductase
EKBHDFBE_01982 1.3e-114 ycaC Q Isochorismatase family
EKBHDFBE_01983 2.7e-224 yugK C Dehydrogenase
EKBHDFBE_01984 1.1e-220 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
EKBHDFBE_01985 2.6e-33 yuzA S Domain of unknown function (DUF378)
EKBHDFBE_01986 7.5e-62 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
EKBHDFBE_01987 1.8e-204 yugH 2.6.1.1 E Aminotransferase
EKBHDFBE_01988 5.8e-83 alaR K Transcriptional regulator
EKBHDFBE_01989 4.5e-149 yugF I Hydrolase
EKBHDFBE_01990 1.2e-36 yugE S Domain of unknown function (DUF1871)
EKBHDFBE_01991 1.9e-217 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
EKBHDFBE_01992 1.1e-221 T PhoQ Sensor
EKBHDFBE_01993 4.3e-62 kapB G Kinase associated protein B
EKBHDFBE_01994 4.9e-116 kapD L the KinA pathway to sporulation
EKBHDFBE_01995 6.3e-188 yuxJ EGP Major facilitator Superfamily
EKBHDFBE_01996 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
EKBHDFBE_01997 1e-69 yuxK S protein conserved in bacteria
EKBHDFBE_01998 6.4e-75 yufK S Family of unknown function (DUF5366)
EKBHDFBE_01999 6.4e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
EKBHDFBE_02000 1.5e-124 dcuR T COG4565 Response regulator of citrate malate metabolism
EKBHDFBE_02001 1.1e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
EKBHDFBE_02002 8e-277 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
EKBHDFBE_02003 1.1e-181 yufP S Belongs to the binding-protein-dependent transport system permease family
EKBHDFBE_02004 7e-170 yufQ S Belongs to the binding-protein-dependent transport system permease family
EKBHDFBE_02005 5.7e-11
EKBHDFBE_02006 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
EKBHDFBE_02007 2.9e-67 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EKBHDFBE_02008 3.7e-49 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EKBHDFBE_02009 1.8e-257 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EKBHDFBE_02010 1.6e-74 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EKBHDFBE_02011 2.7e-37 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EKBHDFBE_02012 2.8e-58 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
EKBHDFBE_02013 1.7e-58 ydiI Q protein, possibly involved in aromatic compounds catabolism
EKBHDFBE_02014 8.1e-114 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EKBHDFBE_02015 1.2e-260 comP 2.7.13.3 T Histidine kinase
EKBHDFBE_02017 7.3e-62 comQ H Belongs to the FPP GGPP synthase family
EKBHDFBE_02019 1.2e-47 yuzC
EKBHDFBE_02020 1.8e-223 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
EKBHDFBE_02021 6.5e-276 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EKBHDFBE_02022 1.8e-101 pncA Q COG1335 Amidases related to nicotinamidase
EKBHDFBE_02023 4.3e-65 yueI S Protein of unknown function (DUF1694)
EKBHDFBE_02024 6.9e-37 yueH S YueH-like protein
EKBHDFBE_02025 4.5e-32 yueG S Spore germination protein gerPA/gerPF
EKBHDFBE_02026 3.7e-183 yueF S transporter activity
EKBHDFBE_02027 1.6e-22 S Protein of unknown function (DUF2642)
EKBHDFBE_02028 1.6e-94 yueE S phosphohydrolase
EKBHDFBE_02029 5.8e-124 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKBHDFBE_02030 1.2e-74 yueC S Family of unknown function (DUF5383)
EKBHDFBE_02031 0.0 esaA S type VII secretion protein EsaA
EKBHDFBE_02032 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
EKBHDFBE_02033 1.1e-202 essB S WXG100 protein secretion system (Wss), protein YukC
EKBHDFBE_02034 5.6e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
EKBHDFBE_02035 6.2e-45 esxA S Belongs to the WXG100 family
EKBHDFBE_02036 1.2e-225 yukF QT Transcriptional regulator
EKBHDFBE_02037 2.8e-202 ald 1.4.1.1 E Belongs to the AlaDH PNT family
EKBHDFBE_02038 3.6e-128 yukJ S Uncharacterized conserved protein (DUF2278)
EKBHDFBE_02039 5.4e-30 mbtH S MbtH-like protein
EKBHDFBE_02040 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKBHDFBE_02041 3.6e-163 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
EKBHDFBE_02042 3.9e-306 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
EKBHDFBE_02043 4.4e-214 entC 5.4.4.2 HQ Isochorismate synthase
EKBHDFBE_02044 1.9e-128 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EKBHDFBE_02045 9.2e-153 besA S Putative esterase
EKBHDFBE_02046 1.2e-116 yuiH S Oxidoreductase molybdopterin binding domain
EKBHDFBE_02047 4.7e-100 bioY S Biotin biosynthesis protein
EKBHDFBE_02048 1.7e-214 yuiF S antiporter
EKBHDFBE_02049 1.1e-278 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EKBHDFBE_02050 5e-76 yuiD S protein conserved in bacteria
EKBHDFBE_02051 4.3e-115 yuiC S protein conserved in bacteria
EKBHDFBE_02052 2.9e-35 yuiB S Putative membrane protein
EKBHDFBE_02053 3.7e-232 yumB 1.6.99.3 C NADH dehydrogenase
EKBHDFBE_02054 1.5e-183 yumC 1.18.1.2, 1.19.1.1 C reductase
EKBHDFBE_02056 3.7e-182 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EKBHDFBE_02057 6.4e-88 rimJ 2.3.1.128 J Alanine acetyltransferase
EKBHDFBE_02058 3.3e-130 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
EKBHDFBE_02059 1.3e-60 erpA S Belongs to the HesB IscA family
EKBHDFBE_02060 1.7e-159 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EKBHDFBE_02061 2.9e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EKBHDFBE_02062 1.1e-36 yuzB S Belongs to the UPF0349 family
EKBHDFBE_02063 4.8e-204 yutJ 1.6.99.3 C NADH dehydrogenase
EKBHDFBE_02064 2.4e-53 yuzD S protein conserved in bacteria
EKBHDFBE_02065 3.6e-35 yutI O COG0694 Thioredoxin-like proteins and domains
EKBHDFBE_02066 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
EKBHDFBE_02067 2.9e-160 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EKBHDFBE_02068 3.8e-193 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EKBHDFBE_02069 5.1e-240 hom 1.1.1.3 E homoserine dehydrogenase
EKBHDFBE_02070 1e-190 yutH S Spore coat protein
EKBHDFBE_02071 9.8e-83 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
EKBHDFBE_02072 3.9e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EKBHDFBE_02073 7.5e-71 yutE S Protein of unknown function DUF86
EKBHDFBE_02074 3.1e-46 yutD S protein conserved in bacteria
EKBHDFBE_02075 4e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EKBHDFBE_02076 5.6e-191 lytH M Peptidase, M23
EKBHDFBE_02077 1.5e-127 yunB S Sporulation protein YunB (Spo_YunB)
EKBHDFBE_02078 1.4e-256 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
EKBHDFBE_02079 6.9e-142 yunE S membrane transporter protein
EKBHDFBE_02080 2.1e-165 yunF S Protein of unknown function DUF72
EKBHDFBE_02081 3.6e-55 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
EKBHDFBE_02082 4.4e-250 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
EKBHDFBE_02083 3.2e-292 pucR QT COG2508 Regulator of polyketide synthase expression
EKBHDFBE_02087 6.9e-68
EKBHDFBE_02088 2.5e-209 blt EGP Major facilitator Superfamily
EKBHDFBE_02089 5.8e-225 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
EKBHDFBE_02090 1.7e-221 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
EKBHDFBE_02091 1.1e-161 bsn L Ribonuclease
EKBHDFBE_02092 1.2e-197 msmX P Belongs to the ABC transporter superfamily
EKBHDFBE_02093 1.3e-131 yurK K UTRA
EKBHDFBE_02094 3.5e-157 yurL 2.7.1.218 G pfkB family carbohydrate kinase
EKBHDFBE_02095 5.9e-155 yurM P COG0395 ABC-type sugar transport system, permease component
EKBHDFBE_02096 3.1e-156 yurN G Binding-protein-dependent transport system inner membrane component
EKBHDFBE_02097 7.3e-239 yurO G COG1653 ABC-type sugar transport system, periplasmic component
EKBHDFBE_02098 6.3e-182 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
EKBHDFBE_02099 4.5e-158 K helix_turn_helix, mercury resistance
EKBHDFBE_02100 3.9e-14
EKBHDFBE_02101 5.8e-76
EKBHDFBE_02102 3e-21 S Sporulation delaying protein SdpA
EKBHDFBE_02104 7.6e-64 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
EKBHDFBE_02105 4.1e-198 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
EKBHDFBE_02106 3.5e-102 Q ubiE/COQ5 methyltransferase family
EKBHDFBE_02107 4.7e-71 yncE S Protein of unknown function (DUF2691)
EKBHDFBE_02108 8.3e-151 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
EKBHDFBE_02109 2.8e-268 sufB O FeS cluster assembly
EKBHDFBE_02110 1.2e-76 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
EKBHDFBE_02111 2e-230 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EKBHDFBE_02112 7.7e-244 sufD O assembly protein SufD
EKBHDFBE_02113 5.6e-141 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
EKBHDFBE_02115 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EKBHDFBE_02116 1.1e-142 metQ P Belongs to the NlpA lipoprotein family
EKBHDFBE_02117 7.2e-105 metI P COG2011 ABC-type metal ion transport system, permease component
EKBHDFBE_02118 1.8e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EKBHDFBE_02119 1.2e-55 yusD S SCP-2 sterol transfer family
EKBHDFBE_02120 1.2e-52 yusE CO Thioredoxin
EKBHDFBE_02121 3.9e-57 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
EKBHDFBE_02122 4.1e-39 yusG S Protein of unknown function (DUF2553)
EKBHDFBE_02123 1.7e-63 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
EKBHDFBE_02124 1.4e-62 arsC 1.20.4.1 P Belongs to the ArsC family
EKBHDFBE_02125 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
EKBHDFBE_02126 5.7e-214 fadA 2.3.1.16 I Belongs to the thiolase family
EKBHDFBE_02127 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
EKBHDFBE_02129 1.1e-161 fadM E Proline dehydrogenase
EKBHDFBE_02130 5.8e-39
EKBHDFBE_02131 7.8e-52 yusN M Coat F domain
EKBHDFBE_02132 4.5e-66 yusO K Iron dependent repressor, N-terminal DNA binding domain
EKBHDFBE_02133 5.4e-284 yusP P Major facilitator superfamily
EKBHDFBE_02134 6.1e-61 yusQ S Tautomerase enzyme
EKBHDFBE_02135 7.6e-124 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EKBHDFBE_02136 1.5e-155 yusT K LysR substrate binding domain
EKBHDFBE_02137 4e-37 yusU S Protein of unknown function (DUF2573)
EKBHDFBE_02138 1e-148 yusV 3.6.3.34 HP ABC transporter
EKBHDFBE_02139 2.6e-47 S YusW-like protein
EKBHDFBE_02140 0.0 pepF2 E COG1164 Oligoendopeptidase F
EKBHDFBE_02141 1.8e-137 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EKBHDFBE_02142 2e-77 dps P Belongs to the Dps family
EKBHDFBE_02143 4.1e-232 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EKBHDFBE_02144 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKBHDFBE_02145 4.1e-248 cssS 2.7.13.3 T PhoQ Sensor
EKBHDFBE_02146 8.3e-23
EKBHDFBE_02147 7.1e-153 yuxN K Transcriptional regulator
EKBHDFBE_02148 8.1e-260 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EKBHDFBE_02149 8.5e-24 S Protein of unknown function (DUF3970)
EKBHDFBE_02150 1.7e-252 gerAA EG Spore germination protein
EKBHDFBE_02151 4.4e-184 gerAB E Spore germination protein
EKBHDFBE_02152 5.8e-192 gerAC S Spore germination B3/ GerAC like, C-terminal
EKBHDFBE_02153 9.5e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EKBHDFBE_02154 5.1e-193 vraS 2.7.13.3 T Histidine kinase
EKBHDFBE_02155 8.3e-123 yvqF S Cell wall-active antibiotics response 4TMS YvqF
EKBHDFBE_02156 4.6e-128 liaG S Putative adhesin
EKBHDFBE_02157 1.1e-97 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
EKBHDFBE_02158 1.4e-49 liaI S membrane
EKBHDFBE_02159 4.4e-220 yvqJ EGP Major facilitator Superfamily
EKBHDFBE_02160 1.5e-95 yvqK 2.5.1.17 S Adenosyltransferase
EKBHDFBE_02161 4.4e-201 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
EKBHDFBE_02162 1.3e-174 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKBHDFBE_02163 3.9e-165 yvrC P ABC transporter substrate-binding protein
EKBHDFBE_02164 9e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EKBHDFBE_02165 4.3e-166 yvrE G SMP-30/Gluconolaconase/LRE-like region
EKBHDFBE_02166 0.0 T PhoQ Sensor
EKBHDFBE_02167 3.3e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKBHDFBE_02168 1.2e-35
EKBHDFBE_02169 1.9e-101 yvrI K RNA polymerase
EKBHDFBE_02170 4.6e-15 S YvrJ protein family
EKBHDFBE_02171 5.8e-227 oxdC 4.1.1.2 G Oxalate decarboxylase
EKBHDFBE_02172 4.4e-60 yvrL S Regulatory protein YrvL
EKBHDFBE_02173 5e-145 fhuC 3.6.3.34 HP ABC transporter
EKBHDFBE_02174 1.8e-171 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKBHDFBE_02175 8e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKBHDFBE_02176 4.9e-176 fhuD P ABC transporter
EKBHDFBE_02177 3.4e-121 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EKBHDFBE_02178 7e-251 yvsH E Arginine ornithine antiporter
EKBHDFBE_02179 8.6e-13 S Small spore protein J (Spore_SspJ)
EKBHDFBE_02180 8.6e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
EKBHDFBE_02181 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
EKBHDFBE_02182 1.8e-159 yvgK P COG1910 Periplasmic molybdate-binding protein domain
EKBHDFBE_02183 7.1e-136 modA P COG0725 ABC-type molybdate transport system, periplasmic component
EKBHDFBE_02184 1.2e-99 modB P COG4149 ABC-type molybdate transport system, permease component
EKBHDFBE_02185 1.6e-112 yfiK K Regulator
EKBHDFBE_02186 1.5e-184 T Histidine kinase
EKBHDFBE_02187 2.2e-168 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
EKBHDFBE_02188 1.3e-183 yfiM V ABC-2 type transporter
EKBHDFBE_02189 5.2e-180 yfiN V COG0842 ABC-type multidrug transport system, permease component
EKBHDFBE_02190 4.7e-154 yvgN S reductase
EKBHDFBE_02191 6.6e-84 yvgO
EKBHDFBE_02192 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
EKBHDFBE_02193 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
EKBHDFBE_02194 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EKBHDFBE_02195 0.0 helD 3.6.4.12 L DNA helicase
EKBHDFBE_02196 6.3e-100 yvgT S membrane
EKBHDFBE_02197 8.5e-145 S Metallo-peptidase family M12
EKBHDFBE_02198 1.5e-71 bdbC O Required for disulfide bond formation in some proteins
EKBHDFBE_02199 1e-103 bdbD O Thioredoxin
EKBHDFBE_02200 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
EKBHDFBE_02201 0.0 copA 3.6.3.54 P P-type ATPase
EKBHDFBE_02202 6.3e-28 copZ P Heavy-metal-associated domain
EKBHDFBE_02203 9.8e-46 csoR S transcriptional
EKBHDFBE_02204 2.1e-188 yvaA 1.1.1.371 S Oxidoreductase
EKBHDFBE_02205 9.2e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EKBHDFBE_02206 3.8e-159 K Helix-turn-helix XRE-family like proteins
EKBHDFBE_02207 1.1e-212 ynfM EGP Major Facilitator Superfamily
EKBHDFBE_02208 2.4e-66 4.1.1.44 S Carboxymuconolactone decarboxylase family
EKBHDFBE_02209 2.3e-142 S Amidohydrolase
EKBHDFBE_02210 1.2e-247 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKBHDFBE_02211 1.7e-42 ytnI O COG0695 Glutaredoxin and related proteins
EKBHDFBE_02212 1.6e-172 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKBHDFBE_02213 2e-138 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
EKBHDFBE_02214 3.3e-116 tcyM U Binding-protein-dependent transport system inner membrane component
EKBHDFBE_02215 3e-117 tcyL P Binding-protein-dependent transport system inner membrane component
EKBHDFBE_02216 1.6e-143 tcyK M Bacterial periplasmic substrate-binding proteins
EKBHDFBE_02217 1.6e-127 ytmJ ET Bacterial periplasmic substrate-binding proteins
EKBHDFBE_02218 4.8e-99 ytmI K Acetyltransferase (GNAT) domain
EKBHDFBE_02219 6.8e-159 ytlI K LysR substrate binding domain
EKBHDFBE_02220 6.5e-137 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EKBHDFBE_02221 1.5e-41 yrdF K ribonuclease inhibitor
EKBHDFBE_02223 1.3e-81 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EKBHDFBE_02224 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EKBHDFBE_02225 2.4e-141 est 3.1.1.1 S Carboxylesterase
EKBHDFBE_02226 8.6e-26 secG U Preprotein translocase subunit SecG
EKBHDFBE_02227 1e-34 yvzC K Transcriptional
EKBHDFBE_02228 5.6e-68 K transcriptional
EKBHDFBE_02229 1.6e-68 yvaO K Cro/C1-type HTH DNA-binding domain
EKBHDFBE_02230 1.4e-50 yodB K transcriptional
EKBHDFBE_02231 1.4e-243 T His Kinase A (phosphoacceptor) domain
EKBHDFBE_02232 5.6e-118 K Transcriptional regulatory protein, C terminal
EKBHDFBE_02233 7e-128 mutG S ABC-2 family transporter protein
EKBHDFBE_02234 1.3e-118 spaE S ABC-2 family transporter protein
EKBHDFBE_02235 1.4e-122 mutF V ABC transporter, ATP-binding protein
EKBHDFBE_02236 1.5e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
EKBHDFBE_02237 5.9e-166 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EKBHDFBE_02238 8e-109 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
EKBHDFBE_02239 2.1e-205 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EKBHDFBE_02240 6.1e-83 yvbF K Belongs to the GbsR family
EKBHDFBE_02241 1.2e-107 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
EKBHDFBE_02242 9.7e-169 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EKBHDFBE_02243 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
EKBHDFBE_02244 8.2e-210 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EKBHDFBE_02245 3e-96 yvbF K Belongs to the GbsR family
EKBHDFBE_02246 9.8e-104 yvbG U UPF0056 membrane protein
EKBHDFBE_02247 1.6e-115 exoY M Membrane
EKBHDFBE_02248 0.0 tcaA S response to antibiotic
EKBHDFBE_02249 1.8e-78 yvbK 3.1.3.25 K acetyltransferase
EKBHDFBE_02250 3.6e-203 EGP Major facilitator Superfamily
EKBHDFBE_02251 4.3e-169
EKBHDFBE_02252 1e-122 S GlcNAc-PI de-N-acetylase
EKBHDFBE_02253 3.1e-141 C WbqC-like protein family
EKBHDFBE_02254 5.4e-140 M Protein involved in cellulose biosynthesis
EKBHDFBE_02255 3.7e-219 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EKBHDFBE_02256 3.1e-167 5.1.3.2 M GDP-mannose 4,6 dehydratase
EKBHDFBE_02257 3.2e-214 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
EKBHDFBE_02258 4e-248 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EKBHDFBE_02259 3.2e-226 ywaD 3.4.11.10, 3.4.11.6 S PA domain
EKBHDFBE_02260 2.4e-242 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EKBHDFBE_02261 5.4e-297 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
EKBHDFBE_02262 1.1e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EKBHDFBE_02263 1.2e-214 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
EKBHDFBE_02264 1.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EKBHDFBE_02265 1.7e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EKBHDFBE_02267 1.2e-250 araE EGP Major facilitator Superfamily
EKBHDFBE_02268 3.9e-201 araR K transcriptional
EKBHDFBE_02269 6e-188 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKBHDFBE_02271 4.2e-153 yvbU K Transcriptional regulator
EKBHDFBE_02272 9.7e-153 yvbV EG EamA-like transporter family
EKBHDFBE_02273 3.1e-216 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
EKBHDFBE_02275 1.1e-147 ybbH_1 K RpiR family transcriptional regulator
EKBHDFBE_02276 4e-292 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
EKBHDFBE_02277 7.3e-226 gntP EG COG2610 H gluconate symporter and related permeases
EKBHDFBE_02278 5.3e-130 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EKBHDFBE_02279 7.3e-264 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
EKBHDFBE_02280 9.6e-132 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EKBHDFBE_02281 4e-207 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EKBHDFBE_02282 1.8e-117 yvfI K COG2186 Transcriptional regulators
EKBHDFBE_02283 7.6e-297 yvfH C L-lactate permease
EKBHDFBE_02284 2.4e-229 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
EKBHDFBE_02285 4.5e-32 yvfG S YvfG protein
EKBHDFBE_02286 3.8e-176 yvfF GM Exopolysaccharide biosynthesis protein
EKBHDFBE_02287 3.9e-215 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
EKBHDFBE_02288 5.6e-54 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
EKBHDFBE_02289 8e-103 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EKBHDFBE_02290 4e-268 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EKBHDFBE_02291 8.9e-187 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
EKBHDFBE_02292 3.2e-195 epsI GM pyruvyl transferase
EKBHDFBE_02293 1.3e-190 epsH GT2 S Glycosyltransferase like family 2
EKBHDFBE_02294 7.5e-200 epsG S EpsG family
EKBHDFBE_02295 2.7e-197 epsF GT4 M Glycosyl transferases group 1
EKBHDFBE_02296 5e-156 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EKBHDFBE_02297 4.1e-209 epsD GT4 M Glycosyl transferase 4-like
EKBHDFBE_02298 8.5e-243 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
EKBHDFBE_02299 3.1e-68 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
EKBHDFBE_02300 8.3e-117 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
EKBHDFBE_02301 2.5e-116 ywqC M biosynthesis protein
EKBHDFBE_02302 7.3e-77 slr K transcriptional
EKBHDFBE_02303 2.2e-244 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
EKBHDFBE_02305 4.7e-83 ywjB H RibD C-terminal domain
EKBHDFBE_02306 2.9e-130 CH FAD binding domain
EKBHDFBE_02307 3.3e-79 S Metallo-beta-lactamase superfamily
EKBHDFBE_02308 8.8e-105 yyaS S Membrane
EKBHDFBE_02309 3.5e-83 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EKBHDFBE_02310 3e-92 padC Q Phenolic acid decarboxylase
EKBHDFBE_02311 1.6e-49 MA20_18690 S Protein of unknown function (DUF3237)
EKBHDFBE_02312 3.2e-32 S Protein of unknown function (DUF1433)
EKBHDFBE_02313 2.3e-22 S Protein of unknown function (DUF1433)
EKBHDFBE_02314 2.4e-16 S Protein of unknown function (DUF1433)
EKBHDFBE_02315 6e-258 I Pfam Lipase (class 3)
EKBHDFBE_02316 9.9e-33
EKBHDFBE_02318 2.1e-274 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
EKBHDFBE_02319 5.6e-211 rafB P LacY proton/sugar symporter
EKBHDFBE_02320 6e-177 scrR K transcriptional
EKBHDFBE_02321 1.1e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EKBHDFBE_02322 6.1e-157 yraN K Transcriptional regulator
EKBHDFBE_02323 4.8e-202 yraM S PrpF protein
EKBHDFBE_02324 9.2e-248 EGP Sugar (and other) transporter
EKBHDFBE_02325 7.1e-86
EKBHDFBE_02326 1.9e-101 yvdD 3.2.2.10 S Belongs to the LOG family
EKBHDFBE_02327 5e-48 yvdC S MazG nucleotide pyrophosphohydrolase domain
EKBHDFBE_02328 1.2e-278 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
EKBHDFBE_02329 1.5e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
EKBHDFBE_02330 1.2e-177 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EKBHDFBE_02331 7.6e-77 M Ribonuclease
EKBHDFBE_02332 2e-127 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
EKBHDFBE_02333 6e-36 crh G Phosphocarrier protein Chr
EKBHDFBE_02334 2.8e-171 whiA K May be required for sporulation
EKBHDFBE_02335 1e-173 ybhK S Required for morphogenesis under gluconeogenic growth conditions
EKBHDFBE_02336 2.8e-165 rapZ S Displays ATPase and GTPase activities
EKBHDFBE_02337 1.2e-85 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
EKBHDFBE_02338 1.3e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EKBHDFBE_02339 1.8e-156 usp CBM50 M protein conserved in bacteria
EKBHDFBE_02340 1.4e-267 S COG0457 FOG TPR repeat
EKBHDFBE_02341 6.3e-180 sasA T Histidine kinase
EKBHDFBE_02342 1.5e-118 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKBHDFBE_02343 0.0 msbA2 3.6.3.44 V ABC transporter
EKBHDFBE_02344 2.4e-107 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
EKBHDFBE_02345 3.1e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EKBHDFBE_02346 8.1e-126 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EKBHDFBE_02347 4.6e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EKBHDFBE_02348 5.3e-104 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
EKBHDFBE_02349 1.5e-226 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EKBHDFBE_02350 9.9e-112 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
EKBHDFBE_02351 5.5e-201 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EKBHDFBE_02352 8e-134 yvpB NU protein conserved in bacteria
EKBHDFBE_02353 1.1e-84 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
EKBHDFBE_02354 1.4e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
EKBHDFBE_02355 1.2e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EKBHDFBE_02356 4.9e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EKBHDFBE_02357 2e-211 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
EKBHDFBE_02358 9.1e-130 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EKBHDFBE_02359 1.9e-130 yvoA K transcriptional
EKBHDFBE_02360 4.6e-100 yxaF K Transcriptional regulator
EKBHDFBE_02361 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
EKBHDFBE_02362 2.3e-49 yvlD S Membrane
EKBHDFBE_02363 1.2e-25 pspB KT PspC domain
EKBHDFBE_02364 5.7e-168 yvlB S Putative adhesin
EKBHDFBE_02365 5.1e-46 yvlA
EKBHDFBE_02366 1.3e-29 yvkN
EKBHDFBE_02367 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EKBHDFBE_02368 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EKBHDFBE_02369 4.4e-33 csbA S protein conserved in bacteria
EKBHDFBE_02370 0.0 yvkC 2.7.9.2 GT Phosphotransferase
EKBHDFBE_02371 4.1e-93 yvkB K Transcriptional regulator
EKBHDFBE_02372 6e-228 yvkA EGP Major facilitator Superfamily
EKBHDFBE_02373 9.8e-26 yuaB
EKBHDFBE_02374 1.1e-217 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EKBHDFBE_02375 4.9e-54 swrA S Swarming motility protein
EKBHDFBE_02376 8.7e-254 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
EKBHDFBE_02377 6.3e-220 ywoF P Right handed beta helix region
EKBHDFBE_02378 3.9e-154 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
EKBHDFBE_02379 3.9e-122 ftsE D cell division ATP-binding protein FtsE
EKBHDFBE_02380 2.1e-44 cccB C COG2010 Cytochrome c, mono- and diheme variants
EKBHDFBE_02381 7.4e-147 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
EKBHDFBE_02382 1.4e-173 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EKBHDFBE_02383 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EKBHDFBE_02384 7.6e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EKBHDFBE_02385 1.5e-67
EKBHDFBE_02386 4.9e-09 fliT S bacterial-type flagellum organization
EKBHDFBE_02387 4.1e-63 fliS N flagellar protein FliS
EKBHDFBE_02388 7.5e-251 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EKBHDFBE_02389 1.8e-120 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EKBHDFBE_02390 1.7e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EKBHDFBE_02391 1.9e-74 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
EKBHDFBE_02392 8e-81 yviE
EKBHDFBE_02393 9.7e-161 flgL N Belongs to the bacterial flagellin family
EKBHDFBE_02394 5.5e-270 flgK N flagellar hook-associated protein
EKBHDFBE_02395 3.5e-77 flgN NOU FlgN protein
EKBHDFBE_02396 8.7e-38 flgM KNU Negative regulator of flagellin synthesis
EKBHDFBE_02397 5e-72 yvyF S flagellar protein
EKBHDFBE_02398 2.8e-62 comFC S Phosphoribosyl transferase domain
EKBHDFBE_02399 1.1e-41 comFB S Late competence development protein ComFB
EKBHDFBE_02400 6.6e-246 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EKBHDFBE_02401 1.4e-153 degV S protein conserved in bacteria
EKBHDFBE_02402 9.9e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EKBHDFBE_02403 1.2e-192 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
EKBHDFBE_02404 1e-116 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
EKBHDFBE_02405 6e-185 yvhJ K Transcriptional regulator
EKBHDFBE_02406 5.2e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
EKBHDFBE_02407 4e-223 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
EKBHDFBE_02408 4.1e-141 tuaG GT2 M Glycosyltransferase like family 2
EKBHDFBE_02409 1.3e-106 tuaF M protein involved in exopolysaccharide biosynthesis
EKBHDFBE_02410 5.9e-250 tuaE M Teichuronic acid biosynthesis protein
EKBHDFBE_02411 1e-243 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EKBHDFBE_02412 4.1e-212 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
EKBHDFBE_02413 3.8e-252 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EKBHDFBE_02414 3.1e-116 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EKBHDFBE_02415 3.8e-263 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EKBHDFBE_02416 0.0 lytB 3.5.1.28 D Stage II sporulation protein
EKBHDFBE_02417 9.4e-47
EKBHDFBE_02418 3.2e-156 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
EKBHDFBE_02419 1e-205 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
EKBHDFBE_02420 1.1e-161 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
EKBHDFBE_02421 3.3e-270 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
EKBHDFBE_02422 2.8e-151 tagG GM Transport permease protein
EKBHDFBE_02423 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EKBHDFBE_02424 2.8e-285 M Glycosyltransferase like family 2
EKBHDFBE_02425 4.8e-69 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
EKBHDFBE_02426 1.5e-138 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
EKBHDFBE_02427 2e-203 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EKBHDFBE_02428 1.6e-240 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EKBHDFBE_02429 1.5e-180 pmi 5.3.1.8 G mannose-6-phosphate isomerase
EKBHDFBE_02430 1.1e-251 gerBA EG Spore germination protein
EKBHDFBE_02431 3.8e-160 gerBB E Spore germination protein
EKBHDFBE_02432 6e-205 gerAC S Spore germination protein
EKBHDFBE_02433 1.3e-254 GT2,GT4 J Glycosyl transferase family 2
EKBHDFBE_02434 1.4e-240 ywtG EGP Major facilitator Superfamily
EKBHDFBE_02435 5.7e-175 ywtF K Transcriptional regulator
EKBHDFBE_02436 1.7e-151 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
EKBHDFBE_02437 7.9e-49 yttA 2.7.13.3 S Pfam Transposase IS66
EKBHDFBE_02438 5.7e-225 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EKBHDFBE_02439 4.9e-20 ywtC
EKBHDFBE_02440 2.3e-215 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
EKBHDFBE_02441 1.9e-34 pgsC S biosynthesis protein
EKBHDFBE_02442 1.7e-221 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
EKBHDFBE_02443 4.3e-195 gerKA EG Spore germination protein
EKBHDFBE_02444 7.9e-178 gerKB E Spore germination protein
EKBHDFBE_02445 2.4e-193 gerKC S Spore germination B3/ GerAC like, C-terminal
EKBHDFBE_02446 7e-173 rbsR K transcriptional
EKBHDFBE_02447 1.3e-151 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKBHDFBE_02448 6.8e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
EKBHDFBE_02449 1.9e-270 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
EKBHDFBE_02450 1.1e-157 rbsC G Belongs to the binding-protein-dependent transport system permease family
EKBHDFBE_02451 1.8e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
EKBHDFBE_02452 7.8e-86 batE T Sh3 type 3 domain protein
EKBHDFBE_02453 2.6e-86 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
EKBHDFBE_02454 5.3e-144 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
EKBHDFBE_02455 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
EKBHDFBE_02456 5.4e-164 alsR K LysR substrate binding domain
EKBHDFBE_02458 6.2e-233 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EKBHDFBE_02459 1.2e-115 ywrJ
EKBHDFBE_02460 5.3e-124 cotB
EKBHDFBE_02461 1.9e-203 cotH M Spore Coat
EKBHDFBE_02462 3.7e-07
EKBHDFBE_02463 9e-110 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EKBHDFBE_02465 4.7e-288 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
EKBHDFBE_02466 1.1e-80 ywrC K Transcriptional regulator
EKBHDFBE_02467 8.3e-97 ywrB P Chromate transporter
EKBHDFBE_02468 1e-85 ywrA P COG2059 Chromate transport protein ChrA
EKBHDFBE_02469 2.3e-100
EKBHDFBE_02470 6.2e-47
EKBHDFBE_02471 2.1e-73 S SMI1 / KNR4 family
EKBHDFBE_02472 3e-17
EKBHDFBE_02473 1.4e-58 S SUKH-4 immunity protein
EKBHDFBE_02474 9.8e-232 ywqJ S Pre-toxin TG
EKBHDFBE_02475 1e-35 ywqI S Family of unknown function (DUF5344)
EKBHDFBE_02476 3.6e-25 S Domain of unknown function (DUF5082)
EKBHDFBE_02477 2.1e-143 ywqG S Domain of unknown function (DUF1963)
EKBHDFBE_02478 5.7e-239 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EKBHDFBE_02479 8.1e-137 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
EKBHDFBE_02480 9.9e-118 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
EKBHDFBE_02481 4e-112 ywqC M biosynthesis protein
EKBHDFBE_02482 4.3e-15
EKBHDFBE_02483 1.7e-298 ywqB S SWIM zinc finger
EKBHDFBE_02484 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
EKBHDFBE_02485 1.1e-150 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
EKBHDFBE_02486 3.4e-138 glcR K DeoR C terminal sensor domain
EKBHDFBE_02487 2.4e-56 ssbB L Single-stranded DNA-binding protein
EKBHDFBE_02488 5.5e-56 ywpG
EKBHDFBE_02489 7.5e-68 ywpF S YwpF-like protein
EKBHDFBE_02490 1.2e-54 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EKBHDFBE_02491 1.4e-74 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EKBHDFBE_02492 3.6e-191 S aspartate phosphatase
EKBHDFBE_02493 5.5e-139 flhP N flagellar basal body
EKBHDFBE_02494 1.1e-133 flhO N flagellar basal body
EKBHDFBE_02495 2e-180 mbl D Rod shape-determining protein
EKBHDFBE_02496 1.7e-44 spoIIID K Stage III sporulation protein D
EKBHDFBE_02497 1.6e-70 ywoH K transcriptional
EKBHDFBE_02498 2.1e-211 ywoG EGP Major facilitator Superfamily
EKBHDFBE_02499 1.8e-270 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
EKBHDFBE_02500 1.3e-241 ywoD EGP Major facilitator superfamily
EKBHDFBE_02501 3.2e-98 phzA Q Isochorismatase family
EKBHDFBE_02502 1.8e-226 amt P Ammonium transporter
EKBHDFBE_02503 6.5e-57 nrgB K Belongs to the P(II) protein family
EKBHDFBE_02504 3.1e-204 ftsW D Belongs to the SEDS family
EKBHDFBE_02505 7.8e-100 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
EKBHDFBE_02506 1.5e-68 ywnJ S VanZ like family
EKBHDFBE_02507 1.6e-136 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
EKBHDFBE_02508 3.2e-86 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
EKBHDFBE_02509 3.4e-18 ywnC S Family of unknown function (DUF5362)
EKBHDFBE_02510 3.9e-67 ywnF S Family of unknown function (DUF5392)
EKBHDFBE_02511 2.3e-273 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EKBHDFBE_02512 1.3e-58 ywnC S Family of unknown function (DUF5362)
EKBHDFBE_02513 2.1e-90 ywnB S NAD(P)H-binding
EKBHDFBE_02514 8e-67 ywnA K Transcriptional regulator
EKBHDFBE_02515 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
EKBHDFBE_02516 1.5e-59 ureB 3.5.1.5 E Belongs to the urease beta subunit family
EKBHDFBE_02517 7.7e-49 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
EKBHDFBE_02518 8.4e-11 csbD K CsbD-like
EKBHDFBE_02519 3e-81 ywmF S Peptidase M50
EKBHDFBE_02520 9e-92 S response regulator aspartate phosphatase
EKBHDFBE_02521 1.1e-189 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EKBHDFBE_02522 3.9e-142 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EKBHDFBE_02524 4e-119 ywmD S protein containing a von Willebrand factor type A (vWA) domain
EKBHDFBE_02525 8.2e-112 ywmC S protein containing a von Willebrand factor type A (vWA) domain
EKBHDFBE_02526 1.1e-181 spoIID D Stage II sporulation protein D
EKBHDFBE_02527 3.4e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EKBHDFBE_02528 4.9e-131 ywmB S TATA-box binding
EKBHDFBE_02529 6.2e-32 ywzB S membrane
EKBHDFBE_02530 2.5e-88 ywmA
EKBHDFBE_02531 3.4e-62 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
EKBHDFBE_02532 3.8e-265 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EKBHDFBE_02533 4.5e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EKBHDFBE_02534 6.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EKBHDFBE_02535 2.6e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EKBHDFBE_02536 5.2e-63 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EKBHDFBE_02537 4.7e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EKBHDFBE_02538 5.4e-130 atpB C it plays a direct role in the translocation of protons across the membrane
EKBHDFBE_02539 1.8e-60 atpI S ATP synthase
EKBHDFBE_02540 6.7e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EKBHDFBE_02541 8.9e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EKBHDFBE_02542 2.1e-94 ywlG S Belongs to the UPF0340 family
EKBHDFBE_02543 5.9e-79 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
EKBHDFBE_02544 1.1e-72 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EKBHDFBE_02545 2.1e-89 mntP P Probably functions as a manganese efflux pump
EKBHDFBE_02546 3.7e-185 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EKBHDFBE_02547 6.3e-73 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
EKBHDFBE_02548 3.9e-114 spoIIR S stage II sporulation protein R
EKBHDFBE_02549 3.7e-58 ywlA S Uncharacterised protein family (UPF0715)
EKBHDFBE_02551 3.5e-152 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EKBHDFBE_02552 8.3e-188 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EKBHDFBE_02553 2.1e-64 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EKBHDFBE_02554 2.3e-88 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
EKBHDFBE_02555 1.9e-151 ywkB S Membrane transport protein
EKBHDFBE_02556 0.0 sfcA 1.1.1.38 C malic enzyme
EKBHDFBE_02557 1.2e-100 tdk 2.7.1.21 F thymidine kinase
EKBHDFBE_02558 1.4e-32 rpmE J Binds the 23S rRNA
EKBHDFBE_02559 6.2e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EKBHDFBE_02560 1.8e-173 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
EKBHDFBE_02561 1.4e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EKBHDFBE_02562 1.2e-109 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EKBHDFBE_02563 1.2e-157 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
EKBHDFBE_02564 1.2e-61 spo0F T COG0784 FOG CheY-like receiver
EKBHDFBE_02565 6.6e-90 ywjG S Domain of unknown function (DUF2529)
EKBHDFBE_02566 4.4e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EKBHDFBE_02567 2e-57 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EKBHDFBE_02568 0.0 fadF C COG0247 Fe-S oxidoreductase
EKBHDFBE_02569 4.4e-206 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
EKBHDFBE_02570 3.3e-175 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
EKBHDFBE_02571 4.1e-43 ywjC
EKBHDFBE_02572 0.0 ywjA V ABC transporter
EKBHDFBE_02573 3.9e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EKBHDFBE_02574 1.4e-116 narI 1.7.5.1 C nitrate reductase, gamma
EKBHDFBE_02575 3.4e-84 narJ 1.7.5.1 C nitrate reductase
EKBHDFBE_02576 2.7e-290 narH 1.7.5.1 C Nitrate reductase, beta
EKBHDFBE_02577 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EKBHDFBE_02578 4.1e-78 arfM T cyclic nucleotide binding
EKBHDFBE_02579 8.7e-125 ywiC S YwiC-like protein
EKBHDFBE_02580 2.7e-126 fnr K helix_turn_helix, cAMP Regulatory protein
EKBHDFBE_02581 4.6e-211 narK P COG2223 Nitrate nitrite transporter
EKBHDFBE_02582 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
EKBHDFBE_02583 6.7e-72 ywiB S protein conserved in bacteria
EKBHDFBE_02585 2.3e-198 ywhL CO amine dehydrogenase activity
EKBHDFBE_02586 5e-82 S aspartate phosphatase
EKBHDFBE_02588 1.9e-166 speB 3.5.3.11 E Belongs to the arginase family
EKBHDFBE_02589 2.6e-157 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EKBHDFBE_02590 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EKBHDFBE_02591 9.4e-74
EKBHDFBE_02592 4.3e-89 ywhD S YwhD family
EKBHDFBE_02593 9.5e-118 ywhC S Peptidase family M50
EKBHDFBE_02594 1.7e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
EKBHDFBE_02595 2e-68 ywhA K Transcriptional regulator
EKBHDFBE_02596 4.9e-241 yhdG_1 E C-terminus of AA_permease
EKBHDFBE_02597 8.6e-87 ywgA 2.1.1.72, 3.1.21.3
EKBHDFBE_02598 1.7e-251 ywfO S COG1078 HD superfamily phosphohydrolases
EKBHDFBE_02599 1.2e-35 ywzC S Belongs to the UPF0741 family
EKBHDFBE_02600 3.6e-108 rsfA_1
EKBHDFBE_02602 4e-50 padR K PadR family transcriptional regulator
EKBHDFBE_02603 2.6e-84 S membrane
EKBHDFBE_02604 1.3e-152 V ABC transporter, ATP-binding protein
EKBHDFBE_02605 2.8e-163 yhcI S ABC transporter (permease)
EKBHDFBE_02608 5.5e-164
EKBHDFBE_02610 5.4e-153 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
EKBHDFBE_02611 1.6e-155 cysL K Transcriptional regulator
EKBHDFBE_02612 1.6e-161 MA20_14895 S Conserved hypothetical protein 698
EKBHDFBE_02613 6.8e-173 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
EKBHDFBE_02614 9.9e-143 ywfI C May function as heme-dependent peroxidase
EKBHDFBE_02615 5.7e-138 IQ Enoyl-(Acyl carrier protein) reductase
EKBHDFBE_02616 9.2e-228 ywfG 2.6.1.83 E Aminotransferase class I and II
EKBHDFBE_02617 2e-206 bacE EGP Major facilitator Superfamily
EKBHDFBE_02618 3.6e-263 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
EKBHDFBE_02619 1.9e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKBHDFBE_02620 9.2e-135 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
EKBHDFBE_02621 4e-110 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
EKBHDFBE_02622 1.3e-216 ywfA EGP Major facilitator Superfamily
EKBHDFBE_02623 6.4e-197 tcaB EGP Major facilitator Superfamily
EKBHDFBE_02624 1.2e-255 lysP E amino acid
EKBHDFBE_02625 0.0 rocB E arginine degradation protein
EKBHDFBE_02626 2.6e-291 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
EKBHDFBE_02627 6.4e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
EKBHDFBE_02628 4.4e-61
EKBHDFBE_02629 1.1e-83 spsL 5.1.3.13 M Spore Coat
EKBHDFBE_02630 8.7e-156 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EKBHDFBE_02631 1.3e-176 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EKBHDFBE_02632 2.3e-128 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EKBHDFBE_02633 1.9e-165 spsG M Spore Coat
EKBHDFBE_02634 3.2e-122 spsF M Spore Coat
EKBHDFBE_02635 7.6e-208 spsE 2.5.1.56 M acid synthase
EKBHDFBE_02636 1.7e-151 spsD 2.3.1.210 K Spore Coat
EKBHDFBE_02637 7.1e-217 spsC E Belongs to the DegT DnrJ EryC1 family
EKBHDFBE_02638 6.6e-257 spsB M Capsule polysaccharide biosynthesis protein
EKBHDFBE_02639 5.1e-139 spsA M Spore Coat
EKBHDFBE_02640 3e-64 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
EKBHDFBE_02641 2.4e-57 ywdK S small membrane protein
EKBHDFBE_02642 2.8e-138 ywdJ F Xanthine uracil
EKBHDFBE_02645 1.3e-146 S aspartate phosphatase
EKBHDFBE_02647 3.1e-88 fic S Fic/DOC family
EKBHDFBE_02651 4.9e-183 S Helix-turn-helix domain
EKBHDFBE_02654 6.1e-66 V ABC transporter
EKBHDFBE_02655 6e-84 S bacteriocin-associated integral membrane protein
EKBHDFBE_02668 1.2e-91 S response regulator aspartate phosphatase
EKBHDFBE_02669 3e-23 S Mitochondrial biogenesis AIM24
EKBHDFBE_02672 2e-07 3.2.1.80, 3.4.24.40 L Protein of unknown function (DUF3991)
EKBHDFBE_02674 8.2e-17 S YolD-like protein
EKBHDFBE_02676 1.6e-25
EKBHDFBE_02677 2.3e-26 radC L RadC-like JAB domain
EKBHDFBE_02679 3.9e-135 S response regulator aspartate phosphatase
EKBHDFBE_02683 1.8e-43 L Transposase IS200 like
EKBHDFBE_02684 1.5e-43 nucA M Deoxyribonuclease NucA/NucB
EKBHDFBE_02687 4.8e-64 L Transposase IS200 like
EKBHDFBE_02688 3.1e-201 L Transposase
EKBHDFBE_02701 5.8e-209 yokA L Recombinase
EKBHDFBE_02702 2.1e-17 S Regulatory protein YrvL
EKBHDFBE_02704 4.7e-120 lldD 1.13.12.4 C FMN-dependent dehydrogenase
EKBHDFBE_02706 1.7e-148 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKBHDFBE_02707 0.0 Q Polyketide synthase of type I
EKBHDFBE_02708 1.7e-191 K helix_turn_helix, Arsenical Resistance Operon Repressor
EKBHDFBE_02709 1.5e-297 IQ AMP-binding enzyme
EKBHDFBE_02710 1.4e-38 ytzC S Protein of unknown function (DUF2524)
EKBHDFBE_02712 5.5e-65 ytrA K GntR family transcriptional regulator
EKBHDFBE_02713 8.1e-157 ytrB P abc transporter atp-binding protein
EKBHDFBE_02714 5.2e-168 S ABC-2 family transporter protein
EKBHDFBE_02715 7e-157 P ABC-2 family transporter protein
EKBHDFBE_02716 1.4e-149
EKBHDFBE_02717 1.6e-123 ytrE V ABC transporter, ATP-binding protein
EKBHDFBE_02718 1.3e-203 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
EKBHDFBE_02719 2.7e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKBHDFBE_02720 1.1e-159 T PhoQ Sensor
EKBHDFBE_02721 4.1e-133 bceA V ABC transporter, ATP-binding protein
EKBHDFBE_02722 0.0 bceB V ABC transporter (permease)
EKBHDFBE_02723 7.9e-118 ywaF S Integral membrane protein
EKBHDFBE_02724 7.5e-206 yttB EGP Major facilitator Superfamily
EKBHDFBE_02725 4.3e-133 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
EKBHDFBE_02726 1.3e-51 ytvB S Protein of unknown function (DUF4257)
EKBHDFBE_02727 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
EKBHDFBE_02728 2.1e-51 ytwF P Sulfurtransferase
EKBHDFBE_02729 4e-73 M Acetyltransferase (GNAT) domain
EKBHDFBE_02730 9e-245 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
EKBHDFBE_02731 1.4e-142 amyC P ABC transporter (permease)
EKBHDFBE_02732 2.9e-165 amyD G Binding-protein-dependent transport system inner membrane component
EKBHDFBE_02733 2.3e-232 msmE G Bacterial extracellular solute-binding protein
EKBHDFBE_02734 8e-180 msmR K Transcriptional regulator
EKBHDFBE_02735 4.4e-25 yteV S Sporulation protein Cse60
EKBHDFBE_02736 2.6e-275 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
EKBHDFBE_02737 6.7e-229 ytfP S HI0933-like protein
EKBHDFBE_02738 3.2e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EKBHDFBE_02739 9.7e-124 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EKBHDFBE_02740 1.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
EKBHDFBE_02741 1.2e-115 ythP V ABC transporter
EKBHDFBE_02742 4.8e-197 ythQ U Bacterial ABC transporter protein EcsB
EKBHDFBE_02743 1.8e-224 pbuO S permease
EKBHDFBE_02744 6.2e-260 pepV 3.5.1.18 E Dipeptidase
EKBHDFBE_02745 5.4e-167 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EKBHDFBE_02746 2.2e-99 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EKBHDFBE_02747 8.6e-157 ytlQ
EKBHDFBE_02748 1.6e-166 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
EKBHDFBE_02749 1.7e-153 ytmP 2.7.1.89 M Phosphotransferase
EKBHDFBE_02750 8.5e-44 ytzH S YtzH-like protein
EKBHDFBE_02751 7e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EKBHDFBE_02752 1.7e-159 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
EKBHDFBE_02753 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
EKBHDFBE_02754 1.4e-50 ytzB S small secreted protein
EKBHDFBE_02755 8.8e-198 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
EKBHDFBE_02756 7.4e-74 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
EKBHDFBE_02757 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
EKBHDFBE_02758 1.5e-144 ytpQ S Belongs to the UPF0354 family
EKBHDFBE_02759 5.9e-106 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EKBHDFBE_02760 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
EKBHDFBE_02761 7.8e-249 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
EKBHDFBE_02762 5e-19 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EKBHDFBE_02763 7.2e-23 ytxH S COG4980 Gas vesicle protein
EKBHDFBE_02764 3.8e-43 ytxJ O Protein of unknown function (DUF2847)
EKBHDFBE_02765 6e-194 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
EKBHDFBE_02766 6e-180 ccpA K catabolite control protein A
EKBHDFBE_02767 2.8e-143 motA N flagellar motor
EKBHDFBE_02768 1.6e-112 motS N Flagellar motor protein
EKBHDFBE_02769 2.5e-222 acuC BQ histone deacetylase
EKBHDFBE_02770 2.7e-109 acuB S Domain in cystathionine beta-synthase and other proteins.
EKBHDFBE_02771 1.1e-118 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
EKBHDFBE_02772 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EKBHDFBE_02773 1.1e-236 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EKBHDFBE_02774 1.2e-46 azlD S Branched-chain amino acid transport protein (AzlD)
EKBHDFBE_02775 3.3e-119 azlC E AzlC protein
EKBHDFBE_02776 1.2e-146 K Transcriptional regulator
EKBHDFBE_02777 5.8e-147 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EKBHDFBE_02778 1.1e-125 E GDSL-like Lipase/Acylhydrolase family
EKBHDFBE_02780 4.1e-08 yhbO 1.11.1.6, 3.5.1.124 S protease
EKBHDFBE_02782 2.7e-211 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EKBHDFBE_02783 2.1e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EKBHDFBE_02784 2.5e-282 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
EKBHDFBE_02785 1.5e-83 ytsP 1.8.4.14 T GAF domain-containing protein
EKBHDFBE_02786 9.3e-107 yttP K Transcriptional regulator
EKBHDFBE_02787 3.3e-144 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
EKBHDFBE_02788 1.1e-271 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EKBHDFBE_02789 7.6e-239 braB E Component of the transport system for branched-chain amino acids
EKBHDFBE_02790 5.2e-204 iscS2 2.8.1.7 E Cysteine desulfurase
EKBHDFBE_02791 3.5e-219 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EKBHDFBE_02792 1.5e-30 sspB S spore protein
EKBHDFBE_02793 1e-298 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EKBHDFBE_02794 4e-295 ytcJ S amidohydrolase
EKBHDFBE_02795 2.9e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EKBHDFBE_02796 1.6e-177 sppA OU signal peptide peptidase SppA
EKBHDFBE_02797 2.9e-79 yteJ S RDD family
EKBHDFBE_02798 1.9e-113 ytfI S Protein of unknown function (DUF2953)
EKBHDFBE_02799 1e-75 ytfJ S Sporulation protein YtfJ
EKBHDFBE_02800 2.1e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EKBHDFBE_02801 6.7e-176 ytxK 2.1.1.72 L DNA methylase
EKBHDFBE_02802 1.5e-217 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EKBHDFBE_02803 1.4e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
EKBHDFBE_02804 8.1e-232 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
EKBHDFBE_02805 5.7e-258 argH 4.3.2.1 E argininosuccinate lyase
EKBHDFBE_02807 7.9e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKBHDFBE_02808 4.4e-126 ytkL S Belongs to the UPF0173 family
EKBHDFBE_02809 6.8e-238 ytoI K transcriptional regulator containing CBS domains
EKBHDFBE_02810 8.4e-45 ytpI S YtpI-like protein
EKBHDFBE_02811 2.3e-173 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
EKBHDFBE_02812 1.1e-21
EKBHDFBE_02813 7.3e-86 ytrI
EKBHDFBE_02814 8.5e-54 ytrH S Sporulation protein YtrH
EKBHDFBE_02815 0.0 dnaE 2.7.7.7 L DNA polymerase
EKBHDFBE_02816 7.8e-222 ytsJ 1.1.1.38 C Malate dehydrogenase
EKBHDFBE_02817 2.7e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EKBHDFBE_02818 9e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
EKBHDFBE_02819 7e-178 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EKBHDFBE_02820 4.4e-303 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
EKBHDFBE_02821 2.1e-61 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
EKBHDFBE_02822 6.8e-193 ytvI S sporulation integral membrane protein YtvI
EKBHDFBE_02823 1.4e-73 yeaL S membrane
EKBHDFBE_02824 5.2e-209 citZ 2.3.3.1 C Belongs to the citrate synthase family
EKBHDFBE_02825 5e-240 icd 1.1.1.42 C isocitrate
EKBHDFBE_02826 8.9e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
EKBHDFBE_02827 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKBHDFBE_02828 1.2e-308 phoR 2.7.13.3 T Signal transduction histidine kinase
EKBHDFBE_02829 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EKBHDFBE_02830 1.3e-151 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EKBHDFBE_02831 4.4e-104 ytaF P Probably functions as a manganese efflux pump
EKBHDFBE_02832 1.6e-95 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EKBHDFBE_02833 1.2e-154 ytbE S reductase
EKBHDFBE_02834 2.2e-197 ytbD EGP Major facilitator Superfamily
EKBHDFBE_02835 7.1e-65 ytcD K Transcriptional regulator
EKBHDFBE_02836 5.3e-192 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EKBHDFBE_02837 7.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EKBHDFBE_02838 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EKBHDFBE_02839 9.1e-259 dnaB L Membrane attachment protein
EKBHDFBE_02840 1.4e-167 dnaI L Primosomal protein DnaI
EKBHDFBE_02841 3.4e-104 ytxB S SNARE associated Golgi protein
EKBHDFBE_02842 1e-148 ytxC S YtxC-like family
EKBHDFBE_02843 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EKBHDFBE_02844 5.8e-146 ysaA S HAD-hyrolase-like
EKBHDFBE_02845 0.0 lytS 2.7.13.3 T Histidine kinase
EKBHDFBE_02846 4.3e-127 lytT T COG3279 Response regulator of the LytR AlgR family
EKBHDFBE_02847 8.7e-51 lrgA S effector of murein hydrolase LrgA
EKBHDFBE_02848 3.6e-112 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
EKBHDFBE_02849 2.8e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EKBHDFBE_02850 6.8e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
EKBHDFBE_02851 2.3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EKBHDFBE_02852 1.3e-38 ysdA S Membrane
EKBHDFBE_02853 1.2e-62 ysdB S Sigma-w pathway protein YsdB
EKBHDFBE_02854 9.9e-205 ysdC G COG1363 Cellulase M and related proteins
EKBHDFBE_02855 1.6e-182 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
EKBHDFBE_02856 4.4e-288 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
EKBHDFBE_02857 3.9e-309 araB 2.7.1.16 C Belongs to the ribulokinase family
EKBHDFBE_02858 2.7e-131 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
EKBHDFBE_02859 2.6e-136 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
EKBHDFBE_02860 1.2e-208 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
EKBHDFBE_02861 1.8e-245 araN G carbohydrate transport
EKBHDFBE_02862 2.1e-163 araP P PFAM binding-protein-dependent transport systems inner membrane component
EKBHDFBE_02863 5.2e-145 araQ G transport system permease
EKBHDFBE_02864 7.1e-294 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
EKBHDFBE_02865 0.0 cstA T Carbon starvation protein
EKBHDFBE_02866 1.2e-244 glcF C Glycolate oxidase
EKBHDFBE_02867 9.7e-253 glcD 1.1.3.15 C FAD binding domain
EKBHDFBE_02868 4.8e-191 ysfB KT regulator
EKBHDFBE_02869 4.9e-31 sspI S Belongs to the SspI family
EKBHDFBE_02870 2.5e-130 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EKBHDFBE_02871 9.8e-194 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EKBHDFBE_02872 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EKBHDFBE_02873 1e-165 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EKBHDFBE_02874 6.9e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EKBHDFBE_02875 6.1e-83 cvpA S membrane protein, required for colicin V production
EKBHDFBE_02876 0.0 polX L COG1796 DNA polymerase IV (family X)
EKBHDFBE_02877 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EKBHDFBE_02878 8e-67 yshE S membrane
EKBHDFBE_02879 2.5e-113 ywbB S Protein of unknown function (DUF2711)
EKBHDFBE_02880 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EKBHDFBE_02881 1.3e-102 fadR K Transcriptional regulator
EKBHDFBE_02882 7.3e-133 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
EKBHDFBE_02883 2.4e-136 etfB C Electron transfer flavoprotein
EKBHDFBE_02884 2.5e-175 etfA C Electron transfer flavoprotein
EKBHDFBE_02885 4.3e-291 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
EKBHDFBE_02886 5.6e-52 trxA O Belongs to the thioredoxin family
EKBHDFBE_02887 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EKBHDFBE_02888 2.1e-211 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
EKBHDFBE_02889 3.8e-78 yslB S Protein of unknown function (DUF2507)
EKBHDFBE_02890 6.3e-108 sdhC C succinate dehydrogenase
EKBHDFBE_02891 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
EKBHDFBE_02892 9.5e-146 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
EKBHDFBE_02893 8.1e-73 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
EKBHDFBE_02894 1.9e-30 gerE K Transcriptional regulator
EKBHDFBE_02895 4e-72 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
EKBHDFBE_02896 4e-150 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
EKBHDFBE_02897 5.3e-198 gerM S COG5401 Spore germination protein
EKBHDFBE_02898 4.9e-131 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EKBHDFBE_02899 6.7e-99 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EKBHDFBE_02900 1.3e-87 ysnB S Phosphoesterase
EKBHDFBE_02905 0.0 ilvB 2.2.1.6 E Acetolactate synthase
EKBHDFBE_02906 7.1e-84 ilvN 2.2.1.6 E Acetolactate synthase
EKBHDFBE_02907 7.7e-191 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EKBHDFBE_02908 2.6e-283 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EKBHDFBE_02909 2.3e-193 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
EKBHDFBE_02910 7.2e-272 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EKBHDFBE_02911 3.4e-114 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EKBHDFBE_02912 4.3e-186 ysoA H Tetratricopeptide repeat
EKBHDFBE_02913 1.7e-224 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EKBHDFBE_02914 4.2e-231 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EKBHDFBE_02915 4.6e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
EKBHDFBE_02916 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EKBHDFBE_02917 7.4e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
EKBHDFBE_02918 2.3e-84 ysxD
EKBHDFBE_02919 3.6e-244 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EKBHDFBE_02920 4e-145 hemX O cytochrome C
EKBHDFBE_02921 1.1e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
EKBHDFBE_02922 6.4e-137 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
EKBHDFBE_02923 1.8e-181 hemB 4.2.1.24 H Belongs to the ALAD family
EKBHDFBE_02924 1e-240 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
EKBHDFBE_02925 2.2e-170 spoVID M stage VI sporulation protein D
EKBHDFBE_02926 3.2e-184 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EKBHDFBE_02927 2.3e-24
EKBHDFBE_02928 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EKBHDFBE_02929 1.3e-230 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EKBHDFBE_02930 1e-123 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
EKBHDFBE_02931 3.6e-153 spoIIB S Sporulation related domain
EKBHDFBE_02932 2.5e-98 maf D septum formation protein Maf
EKBHDFBE_02933 5.7e-68 radC E Belongs to the UPF0758 family
EKBHDFBE_02934 7.7e-266 S Recombinase
EKBHDFBE_02935 1.5e-79 S Pfam:Peptidase_M78
EKBHDFBE_02936 1.5e-66 S sequence-specific DNA binding
EKBHDFBE_02937 1.5e-08 plcR K helix-turn-helix
EKBHDFBE_02940 2.8e-23 S Uncharacterized protein YqaH
EKBHDFBE_02942 8.3e-91 S DNA protection
EKBHDFBE_02943 1.3e-163 S AAA domain
EKBHDFBE_02945 1.4e-72 S Protein of unknown function (DUF669)
EKBHDFBE_02946 0.0 S hydrolase activity
EKBHDFBE_02947 3.1e-64
EKBHDFBE_02948 1.9e-95 S nuclease activity
EKBHDFBE_02949 4.3e-81
EKBHDFBE_02951 8.3e-09
EKBHDFBE_02952 1.1e-59
EKBHDFBE_02955 5.5e-71 S regulation of transcription, DNA-dependent
EKBHDFBE_02956 1.1e-18 N PFAM YcfA family protein
EKBHDFBE_02961 2.3e-79 L phage terminase small subunit
EKBHDFBE_02962 2.7e-297 S Terminase
EKBHDFBE_02963 4.3e-167 S Phage portal protein
EKBHDFBE_02964 6.1e-82 S peptidase activity
EKBHDFBE_02965 5.6e-154 gp36 S capsid protein
EKBHDFBE_02966 4.1e-26
EKBHDFBE_02967 9.9e-38 S Phage gp6-like head-tail connector protein
EKBHDFBE_02968 2e-41 S Phage head-tail joining protein
EKBHDFBE_02969 7.4e-49 S Bacteriophage HK97-gp10, putative tail-component
EKBHDFBE_02971 4e-78 S Phage tail tube protein
EKBHDFBE_02973 0.0 D phage tail tape measure protein
EKBHDFBE_02974 2e-104 S Phage tail protein
EKBHDFBE_02975 1.4e-229 NU Prophage endopeptidase tail
EKBHDFBE_02976 0.0 M Pectate lyase superfamily protein
EKBHDFBE_02977 1.6e-166 S Domain of unknown function (DUF2479)
EKBHDFBE_02980 8.3e-59 S Pfam:Phage_holin_4_1
EKBHDFBE_02981 4.3e-127 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
EKBHDFBE_02983 1.1e-09
EKBHDFBE_02986 1.8e-105 S aspartate phosphatase
EKBHDFBE_02987 4.2e-181 mreB D Rod shape-determining protein MreB
EKBHDFBE_02988 2.3e-156 mreC M Involved in formation and maintenance of cell shape
EKBHDFBE_02989 3.3e-81 mreD M shape-determining protein
EKBHDFBE_02990 1.5e-118 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
EKBHDFBE_02991 2.3e-142 minD D Belongs to the ParA family
EKBHDFBE_02992 2.9e-137 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
EKBHDFBE_02993 2e-155 spoIVFB S Stage IV sporulation protein
EKBHDFBE_02994 5.7e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
EKBHDFBE_02995 5.9e-55 ysxB J ribosomal protein
EKBHDFBE_02996 3.5e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
EKBHDFBE_02997 2.1e-105 spo0B T Sporulation initiation phospho-transferase B, C-terminal
EKBHDFBE_02998 1.9e-242 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EKBHDFBE_02999 3.1e-72 pheB 5.4.99.5 S Belongs to the UPF0735 family
EKBHDFBE_03000 3.9e-156 pheA 4.2.1.51 E Prephenate dehydratase
EKBHDFBE_03001 1.7e-88 niaR S small molecule binding protein (contains 3H domain)
EKBHDFBE_03002 5.2e-212 nifS 2.8.1.7 E Cysteine desulfurase
EKBHDFBE_03003 2.1e-280 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
EKBHDFBE_03004 6.7e-140 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
EKBHDFBE_03005 3.5e-205 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EKBHDFBE_03006 4e-172 safA M spore coat assembly protein SafA
EKBHDFBE_03007 1.2e-47 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EKBHDFBE_03009 1e-90 bofC S BofC C-terminal domain
EKBHDFBE_03010 2.9e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EKBHDFBE_03011 9.2e-181 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EKBHDFBE_03012 3.6e-20 yrzS S Protein of unknown function (DUF2905)
EKBHDFBE_03013 3.8e-190 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EKBHDFBE_03014 1.5e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EKBHDFBE_03015 2.5e-37 yajC U Preprotein translocase subunit YajC
EKBHDFBE_03016 1.8e-60 yrzE S Protein of unknown function (DUF3792)
EKBHDFBE_03017 3e-103 yrbG S membrane
EKBHDFBE_03018 5e-266 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EKBHDFBE_03019 6.1e-48 yrzD S Post-transcriptional regulator
EKBHDFBE_03020 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EKBHDFBE_03021 2e-80 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
EKBHDFBE_03022 3.4e-44 yrvD S Lipopolysaccharide assembly protein A domain
EKBHDFBE_03023 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
EKBHDFBE_03024 4.2e-89 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EKBHDFBE_03025 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EKBHDFBE_03026 7.4e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EKBHDFBE_03027 3e-271 lytH 3.5.1.28 M COG3103 SH3 domain protein
EKBHDFBE_03030 2.1e-238 hisS 6.1.1.21 J histidyl-tRNA synthetase
EKBHDFBE_03031 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EKBHDFBE_03032 3.3e-138 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
EKBHDFBE_03033 1.1e-234 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
EKBHDFBE_03034 6.5e-63 cymR K Transcriptional regulator
EKBHDFBE_03035 5e-207 iscS 2.8.1.7 E Cysteine desulfurase
EKBHDFBE_03036 4.7e-218 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EKBHDFBE_03037 5.2e-19 S COG0457 FOG TPR repeat
EKBHDFBE_03038 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EKBHDFBE_03039 2.8e-76 yrrD S protein conserved in bacteria
EKBHDFBE_03040 1.4e-29 yrzR
EKBHDFBE_03041 6e-08 S Protein of unknown function (DUF3918)
EKBHDFBE_03042 6.4e-106 glnP P ABC transporter
EKBHDFBE_03043 2.6e-107 gluC P ABC transporter
EKBHDFBE_03044 3.1e-142 glnH ET Belongs to the bacterial solute-binding protein 3 family
EKBHDFBE_03045 1.2e-126 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
EKBHDFBE_03046 2.3e-174 yrrI S AI-2E family transporter
EKBHDFBE_03047 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EKBHDFBE_03048 2.4e-40 yrzL S Belongs to the UPF0297 family
EKBHDFBE_03049 2.7e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EKBHDFBE_03050 3.5e-45 yrzB S Belongs to the UPF0473 family
EKBHDFBE_03051 1.8e-190 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EKBHDFBE_03052 2.7e-112 yrrM 2.1.1.104 S O-methyltransferase
EKBHDFBE_03053 1.2e-171 yegQ O Peptidase U32
EKBHDFBE_03054 6.3e-243 yegQ O COG0826 Collagenase and related proteases
EKBHDFBE_03055 1.8e-113 udk 2.7.1.48 F Cytidine monophosphokinase
EKBHDFBE_03056 2.9e-76 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EKBHDFBE_03057 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
EKBHDFBE_03058 3e-93 yrrS S Protein of unknown function (DUF1510)
EKBHDFBE_03059 1.4e-27 yrzA S Protein of unknown function (DUF2536)
EKBHDFBE_03060 8.1e-114 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
EKBHDFBE_03061 2.5e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EKBHDFBE_03062 7.2e-164 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
EKBHDFBE_03063 4.8e-210 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EKBHDFBE_03064 3.9e-34 yrhC S YrhC-like protein
EKBHDFBE_03065 5.5e-78 yrhD S Protein of unknown function (DUF1641)
EKBHDFBE_03066 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
EKBHDFBE_03067 1.9e-59 yrhF S Uncharacterized conserved protein (DUF2294)
EKBHDFBE_03068 3.5e-138 focA P Formate nitrite
EKBHDFBE_03070 1.6e-86 yrhH Q methyltransferase
EKBHDFBE_03071 3e-96 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
EKBHDFBE_03072 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
EKBHDFBE_03073 4.5e-206 ynfM EGP Major facilitator Superfamily
EKBHDFBE_03074 2.8e-160 yybE K Transcriptional regulator
EKBHDFBE_03075 2.3e-73 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EKBHDFBE_03076 2.2e-165 romA S Beta-lactamase superfamily domain
EKBHDFBE_03077 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
EKBHDFBE_03078 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
EKBHDFBE_03079 3.4e-169 manA 5.3.1.8 G mannose-6-phosphate isomerase
EKBHDFBE_03080 2e-121 glvR K Helix-turn-helix domain, rpiR family
EKBHDFBE_03081 4.9e-140 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
EKBHDFBE_03082 7.7e-138 S hydrolase
EKBHDFBE_03083 2.4e-89 yrdA S DinB family
EKBHDFBE_03084 4.3e-221 tetL EGP Major facilitator Superfamily
EKBHDFBE_03085 2e-97 adk 2.7.4.3 F adenylate kinase activity
EKBHDFBE_03086 5.1e-87 K Transcriptional regulator PadR-like family
EKBHDFBE_03087 3.5e-157 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
EKBHDFBE_03089 8.3e-123 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EKBHDFBE_03090 1.1e-202 EGP Major facilitator Superfamily
EKBHDFBE_03092 2.3e-105 yqeD S SNARE associated Golgi protein
EKBHDFBE_03093 4.1e-109 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EKBHDFBE_03094 2.3e-133 3.5.1.104 G Polysaccharide deacetylase
EKBHDFBE_03095 1.2e-134 yqeF E GDSL-like Lipase/Acylhydrolase
EKBHDFBE_03097 2.9e-93 yqeG S hydrolase of the HAD superfamily
EKBHDFBE_03098 2.7e-210 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
EKBHDFBE_03099 1.6e-149 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EKBHDFBE_03100 1.2e-43 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
EKBHDFBE_03101 4.8e-102 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EKBHDFBE_03102 5.3e-101 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
EKBHDFBE_03103 1.4e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EKBHDFBE_03104 1.3e-134 yqeM Q Methyltransferase
EKBHDFBE_03105 5.6e-144 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EKBHDFBE_03106 3.1e-94 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
EKBHDFBE_03107 2.6e-103 comEB 3.5.4.12 F ComE operon protein 2
EKBHDFBE_03108 0.0 comEC S Competence protein ComEC
EKBHDFBE_03109 9.2e-15 S YqzM-like protein
EKBHDFBE_03110 3.3e-178 holA 2.7.7.7 L DNA polymerase III delta subunit
EKBHDFBE_03111 6.9e-35 rpsT J Binds directly to 16S ribosomal RNA
EKBHDFBE_03112 6.1e-202 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EKBHDFBE_03113 2.5e-217 spoIIP M stage II sporulation protein P
EKBHDFBE_03114 6.1e-52 yqxA S Protein of unknown function (DUF3679)
EKBHDFBE_03115 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EKBHDFBE_03116 3.1e-209 hemN H Involved in the biosynthesis of porphyrin-containing compound
EKBHDFBE_03117 2.2e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EKBHDFBE_03118 3.2e-82 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EKBHDFBE_03119 0.0 dnaK O Heat shock 70 kDa protein
EKBHDFBE_03120 3.2e-206 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EKBHDFBE_03121 1e-173 prmA J Methylates ribosomal protein L11
EKBHDFBE_03122 2.2e-137 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EKBHDFBE_03123 2.4e-256 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
EKBHDFBE_03124 2.9e-152 yqeW P COG1283 Na phosphate symporter
EKBHDFBE_03125 1.3e-18 rpsU J Belongs to the bacterial ribosomal protein bS21 family
EKBHDFBE_03126 4.2e-69 yqeY S Yqey-like protein
EKBHDFBE_03127 3.6e-225 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
EKBHDFBE_03128 3.3e-146 yqfA S UPF0365 protein
EKBHDFBE_03129 6e-36 yqfB
EKBHDFBE_03130 2e-45 yqfC S sporulation protein YqfC
EKBHDFBE_03131 3e-215 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
EKBHDFBE_03132 4e-173 phoH T Phosphate starvation-inducible protein PhoH
EKBHDFBE_03133 0.0 yqfF S membrane-associated HD superfamily hydrolase
EKBHDFBE_03134 1.6e-79 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EKBHDFBE_03135 9.5e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
EKBHDFBE_03136 6e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
EKBHDFBE_03137 1.2e-166 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EKBHDFBE_03138 2.2e-16 S YqzL-like protein
EKBHDFBE_03139 2.1e-140 recO L Involved in DNA repair and RecF pathway recombination
EKBHDFBE_03140 4.5e-171 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
EKBHDFBE_03141 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
EKBHDFBE_03142 3.8e-111 ccpN K CBS domain
EKBHDFBE_03143 3.5e-146 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
EKBHDFBE_03144 6.2e-85 yaiI S Belongs to the UPF0178 family
EKBHDFBE_03145 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EKBHDFBE_03146 3.8e-199 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EKBHDFBE_03147 2.9e-60 cccA C COG2010 Cytochrome c, mono- and diheme variants
EKBHDFBE_03148 5.6e-122 trmK 2.1.1.217 S SAM-dependent methyltransferase
EKBHDFBE_03149 1.1e-206 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EKBHDFBE_03150 4.2e-175 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EKBHDFBE_03151 5.2e-45 yqfQ S YqfQ-like protein
EKBHDFBE_03152 6.3e-238 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EKBHDFBE_03153 1.5e-161 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EKBHDFBE_03154 7.8e-36 yqfT S Protein of unknown function (DUF2624)
EKBHDFBE_03155 6e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
EKBHDFBE_03156 2.8e-75 zur P Belongs to the Fur family
EKBHDFBE_03157 3e-107 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
EKBHDFBE_03158 1.1e-59 yqfX S membrane
EKBHDFBE_03159 2.5e-198 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EKBHDFBE_03160 7.1e-44 yqfZ M LysM domain
EKBHDFBE_03161 6.9e-128 yqgB S Protein of unknown function (DUF1189)
EKBHDFBE_03162 6.2e-74 yqgC S protein conserved in bacteria
EKBHDFBE_03163 7.6e-114 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
EKBHDFBE_03164 6.2e-222 yqgE EGP Major facilitator superfamily
EKBHDFBE_03165 0.0 pbpA 3.4.16.4 M penicillin-binding protein
EKBHDFBE_03166 8.9e-159 pstS P Phosphate
EKBHDFBE_03167 2e-158 pstC P probably responsible for the translocation of the substrate across the membrane
EKBHDFBE_03168 5.5e-153 pstA P Phosphate transport system permease
EKBHDFBE_03169 4.1e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EKBHDFBE_03170 4.9e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EKBHDFBE_03171 3.8e-73 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EKBHDFBE_03172 3.1e-51 yqzD
EKBHDFBE_03173 3.5e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EKBHDFBE_03174 6e-89 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EKBHDFBE_03175 3e-07 yqgO
EKBHDFBE_03176 2.6e-212 nhaC C Na H antiporter
EKBHDFBE_03177 5.8e-27 yqgQ S Protein conserved in bacteria
EKBHDFBE_03178 3.5e-177 glcK 2.7.1.2 G Glucokinase
EKBHDFBE_03179 1.3e-202 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
EKBHDFBE_03180 2.1e-188 yqgU
EKBHDFBE_03181 2.4e-47 yqgV S Thiamine-binding protein
EKBHDFBE_03182 4.1e-20 yqgW S Protein of unknown function (DUF2759)
EKBHDFBE_03183 2e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
EKBHDFBE_03184 8.9e-37 yqgY S Protein of unknown function (DUF2626)
EKBHDFBE_03185 3.3e-62 yqgZ 1.20.4.1 P Belongs to the ArsC family
EKBHDFBE_03187 1.4e-137 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EKBHDFBE_03188 1.9e-231 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
EKBHDFBE_03189 9.6e-180 corA P Mg2 transporter protein
EKBHDFBE_03190 5.2e-198 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EKBHDFBE_03191 2.2e-177 comGB NU COG1459 Type II secretory pathway, component PulF
EKBHDFBE_03192 4.4e-49 comGC U Required for transformation and DNA binding
EKBHDFBE_03193 2.7e-68 gspH NU Tfp pilus assembly protein FimT
EKBHDFBE_03194 6.4e-19 comGE
EKBHDFBE_03195 2.6e-20 comGF U Putative Competence protein ComGF
EKBHDFBE_03196 2.7e-56 S ComG operon protein 7
EKBHDFBE_03197 9.7e-25 yqzE S YqzE-like protein
EKBHDFBE_03198 1.6e-52 yqzG S Protein of unknown function (DUF3889)
EKBHDFBE_03199 6.7e-111 yqxM
EKBHDFBE_03200 1.3e-73 sipW 3.4.21.89 U Signal peptidase
EKBHDFBE_03201 1.7e-137 tasA S Cell division protein FtsN
EKBHDFBE_03202 1.5e-53 sinR K transcriptional
EKBHDFBE_03203 8.2e-21 sinI S Anti-repressor SinI
EKBHDFBE_03204 4.8e-148 yqhG S Bacterial protein YqhG of unknown function
EKBHDFBE_03205 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
EKBHDFBE_03206 7e-198 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
EKBHDFBE_03207 2.7e-244 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EKBHDFBE_03208 8.3e-279 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EKBHDFBE_03209 1e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
EKBHDFBE_03210 2.2e-156 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
EKBHDFBE_03211 2.1e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
EKBHDFBE_03212 3.3e-158 yqhO S esterase of the alpha-beta hydrolase superfamily
EKBHDFBE_03213 2.4e-60 yqhP
EKBHDFBE_03214 5e-168 yqhQ S Protein of unknown function (DUF1385)
EKBHDFBE_03215 2e-86 yqhR S Conserved membrane protein YqhR
EKBHDFBE_03216 9.4e-192 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
EKBHDFBE_03217 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EKBHDFBE_03218 8.6e-36 yqhV S Protein of unknown function (DUF2619)
EKBHDFBE_03219 2.2e-165 spoIIIAA S stage III sporulation protein AA
EKBHDFBE_03220 1.2e-83 spoIIIAB S Stage III sporulation protein
EKBHDFBE_03221 1.7e-28 spoIIIAC S stage III sporulation protein AC
EKBHDFBE_03222 7.3e-41 spoIIIAD S Stage III sporulation protein AD
EKBHDFBE_03223 5.5e-204 spoIIIAE S stage III sporulation protein AE
EKBHDFBE_03224 8.4e-100 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
EKBHDFBE_03225 2.4e-111 spoIIIAG S stage III sporulation protein AG
EKBHDFBE_03226 2.6e-67 spoIIIAH S SpoIIIAH-like protein
EKBHDFBE_03227 1.3e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EKBHDFBE_03228 1.2e-252 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
EKBHDFBE_03229 8.9e-66 yqhY S protein conserved in bacteria
EKBHDFBE_03230 1.6e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EKBHDFBE_03231 9.6e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EKBHDFBE_03232 1.3e-241 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EKBHDFBE_03233 1.7e-38 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EKBHDFBE_03234 4.1e-156 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EKBHDFBE_03235 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EKBHDFBE_03236 1.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
EKBHDFBE_03237 1.2e-76 argR K Regulates arginine biosynthesis genes
EKBHDFBE_03238 6.2e-310 recN L May be involved in recombinational repair of damaged DNA
EKBHDFBE_03239 9.2e-234 rseP 3.4.21.116 M Stage IV sporulation protein B
EKBHDFBE_03240 9.4e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
EKBHDFBE_03241 7e-204 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EKBHDFBE_03244 6.4e-207 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
EKBHDFBE_03246 4.8e-111 K Protein of unknown function (DUF1232)
EKBHDFBE_03247 3.9e-92 ytaF P Probably functions as a manganese efflux pump
EKBHDFBE_03248 2.8e-16
EKBHDFBE_03249 1.8e-97 amiC 3.5.1.28 M Cell wall hydrolase autolysin
EKBHDFBE_03250 8.1e-126 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
EKBHDFBE_03251 1.2e-208 mmgA 2.3.1.9 I Belongs to the thiolase family
EKBHDFBE_03252 1.5e-144 hbdA 1.1.1.157 I Dehydrogenase
EKBHDFBE_03253 7.7e-200 mmgC I acyl-CoA dehydrogenase
EKBHDFBE_03254 1.9e-203 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
EKBHDFBE_03255 7.3e-264 prpD 4.2.1.79 S 2-methylcitrate dehydratase
EKBHDFBE_03256 7.8e-155 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EKBHDFBE_03257 1.5e-33 yqzF S Protein of unknown function (DUF2627)
EKBHDFBE_03258 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
EKBHDFBE_03259 3.4e-150 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
EKBHDFBE_03260 7.2e-203 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
EKBHDFBE_03261 2.1e-202 buk 2.7.2.7 C Belongs to the acetokinase family
EKBHDFBE_03262 4.1e-259 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EKBHDFBE_03263 5.5e-170 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EKBHDFBE_03264 6.3e-182 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EKBHDFBE_03265 1.1e-207 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EKBHDFBE_03266 6.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EKBHDFBE_03267 1.3e-75 yqiW S Belongs to the UPF0403 family
EKBHDFBE_03268 1.2e-132 artP ET Belongs to the bacterial solute-binding protein 3 family
EKBHDFBE_03269 8.1e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
EKBHDFBE_03270 1.7e-123 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
EKBHDFBE_03271 5.9e-169 yqjA S Putative aromatic acid exporter C-terminal domain
EKBHDFBE_03272 8e-91 yqjB S protein conserved in bacteria
EKBHDFBE_03274 2.8e-70 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
EKBHDFBE_03275 4.1e-281 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EKBHDFBE_03276 8.9e-201 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
EKBHDFBE_03277 3.4e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EKBHDFBE_03278 9.5e-27 yqzJ
EKBHDFBE_03279 2.1e-230 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EKBHDFBE_03280 3.8e-265 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EKBHDFBE_03281 2.5e-283 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EKBHDFBE_03282 7e-167 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EKBHDFBE_03283 7.4e-18 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EKBHDFBE_03284 4.5e-143 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EKBHDFBE_03285 3.1e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
EKBHDFBE_03286 1.1e-45 S GlpM protein
EKBHDFBE_03287 1.5e-158 K LysR substrate binding domain
EKBHDFBE_03288 1.1e-92 nusG K Participates in transcription elongation, termination and antitermination
EKBHDFBE_03289 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EKBHDFBE_03290 3.9e-140 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EKBHDFBE_03291 3.6e-166 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
EKBHDFBE_03292 1.6e-135 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
EKBHDFBE_03293 2.2e-238 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
EKBHDFBE_03294 2.5e-175 coaA 2.7.1.33 F Pantothenic acid kinase
EKBHDFBE_03296 1.3e-161 yueF S transporter activity
EKBHDFBE_03298 9.2e-56 S YolD-like protein
EKBHDFBE_03299 2.2e-229 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EKBHDFBE_03300 2.3e-86 yqjY K acetyltransferase
EKBHDFBE_03302 1.1e-165 yqkA K GrpB protein
EKBHDFBE_03303 1e-57 yqkB S Belongs to the HesB IscA family
EKBHDFBE_03304 7.1e-39 yqkC S Protein of unknown function (DUF2552)
EKBHDFBE_03305 3e-162 yqkD S COG1073 Hydrolases of the alpha beta superfamily
EKBHDFBE_03306 3.8e-10 yqkE S Protein of unknown function (DUF3886)
EKBHDFBE_03307 8.5e-165 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
EKBHDFBE_03309 3.4e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
EKBHDFBE_03310 1.4e-212 yqxK 3.6.4.12 L DNA helicase
EKBHDFBE_03311 1.1e-56 ansR K Transcriptional regulator
EKBHDFBE_03312 8.8e-184 ansA 3.5.1.1 EJ L-asparaginase
EKBHDFBE_03313 1.8e-267 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
EKBHDFBE_03314 1.5e-245 mleN C Na H antiporter
EKBHDFBE_03315 6.7e-240 mleA 1.1.1.38 C malic enzyme
EKBHDFBE_03316 4.6e-24
EKBHDFBE_03317 1.8e-31 yqkK
EKBHDFBE_03318 4.6e-109 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
EKBHDFBE_03319 8.5e-78 fur P Belongs to the Fur family
EKBHDFBE_03320 8.2e-37 S Protein of unknown function (DUF4227)
EKBHDFBE_03321 5.3e-164 xerD L recombinase XerD
EKBHDFBE_03322 3.8e-226 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
EKBHDFBE_03323 1.9e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EKBHDFBE_03324 2.9e-210 dacF 3.4.16.4 M Belongs to the peptidase S11 family
EKBHDFBE_03325 1.7e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
EKBHDFBE_03326 4.6e-76 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
EKBHDFBE_03327 1e-134 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EKBHDFBE_03328 2.2e-108 spoVAA S Stage V sporulation protein AA
EKBHDFBE_03329 3.4e-68 spoVAB S Stage V sporulation protein AB
EKBHDFBE_03330 1.3e-78 spoVAC S stage V sporulation protein AC
EKBHDFBE_03331 1.3e-187 spoVAD I Stage V sporulation protein AD
EKBHDFBE_03332 9.3e-56 spoVAEB S stage V sporulation protein
EKBHDFBE_03333 1.2e-106 spoVAEA S stage V sporulation protein
EKBHDFBE_03334 3.1e-265 spoVAF EG Stage V sporulation protein AF
EKBHDFBE_03335 4e-248 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EKBHDFBE_03336 1.4e-151 ypuA S Secreted protein
EKBHDFBE_03337 9.7e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EKBHDFBE_03338 6.1e-77 ccdC1 O Protein of unknown function (DUF1453)
EKBHDFBE_03339 3e-96 sipT 3.4.21.89 U Belongs to the peptidase S26 family
EKBHDFBE_03340 6.8e-51 ypuD
EKBHDFBE_03341 3.1e-201 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EKBHDFBE_03342 7.9e-109 ribE 2.5.1.9 H Riboflavin synthase
EKBHDFBE_03343 2.9e-221 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EKBHDFBE_03344 1.9e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
EKBHDFBE_03345 3.8e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EKBHDFBE_03346 1.4e-87 ypuF S Domain of unknown function (DUF309)
EKBHDFBE_03348 5.2e-128 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EKBHDFBE_03349 4.3e-101 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EKBHDFBE_03350 1.8e-81 ypuI S Protein of unknown function (DUF3907)
EKBHDFBE_03351 2.9e-210 dacB 3.4.16.4 M Belongs to the peptidase S11 family
EKBHDFBE_03352 5.9e-103 spmA S Spore maturation protein
EKBHDFBE_03353 4.9e-88 spmB S Spore maturation protein
EKBHDFBE_03354 1.7e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EKBHDFBE_03355 1.3e-96 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
EKBHDFBE_03356 5.5e-308 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
EKBHDFBE_03357 1.3e-197 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
EKBHDFBE_03358 5.7e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKBHDFBE_03359 0.0 resE 2.7.13.3 T Histidine kinase
EKBHDFBE_03360 8.5e-102 sigX K Belongs to the sigma-70 factor family. ECF subfamily
EKBHDFBE_03361 2.1e-170 rsiX
EKBHDFBE_03362 3.1e-292 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EKBHDFBE_03363 4.1e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EKBHDFBE_03364 1.7e-40 fer C Ferredoxin
EKBHDFBE_03365 7.4e-189 ypbB 5.1.3.1 S protein conserved in bacteria
EKBHDFBE_03366 3.6e-274 recQ 3.6.4.12 L DNA helicase
EKBHDFBE_03367 1.2e-95 ypbD S metal-dependent membrane protease
EKBHDFBE_03368 6.6e-86 ypbE M Lysin motif
EKBHDFBE_03369 4e-83 ypbF S Protein of unknown function (DUF2663)
EKBHDFBE_03370 3.3e-141 ypbG S Calcineurin-like phosphoesterase superfamily domain
EKBHDFBE_03371 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EKBHDFBE_03372 4.8e-243 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
EKBHDFBE_03373 1.1e-183 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
EKBHDFBE_03374 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
EKBHDFBE_03375 5.6e-158 sleB 3.5.1.28 M Spore cortex-lytic enzyme
EKBHDFBE_03376 5.5e-245 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
EKBHDFBE_03377 2.7e-56 ypfA M Flagellar protein YcgR
EKBHDFBE_03378 9.2e-12 S Family of unknown function (DUF5359)
EKBHDFBE_03379 2e-110 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
EKBHDFBE_03380 6.8e-204 rpsA 1.17.7.4 J Ribosomal protein S1
EKBHDFBE_03381 3.7e-180 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EKBHDFBE_03382 1.4e-07 S YpzI-like protein
EKBHDFBE_03383 3.1e-99 yphA
EKBHDFBE_03384 1.9e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
EKBHDFBE_03385 5.2e-187 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
EKBHDFBE_03386 1.9e-16 yphE S Protein of unknown function (DUF2768)
EKBHDFBE_03387 1e-128 yphF
EKBHDFBE_03389 1.2e-277 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EKBHDFBE_03390 9.4e-43 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EKBHDFBE_03391 1.6e-100 folE 3.5.4.16 H GTP cyclohydrolase
EKBHDFBE_03392 2.9e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
EKBHDFBE_03393 9e-136 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
EKBHDFBE_03394 3.4e-129 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
EKBHDFBE_03395 1.4e-195 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EKBHDFBE_03396 6.5e-78 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
EKBHDFBE_03397 6.3e-137 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
EKBHDFBE_03398 5.7e-214 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EKBHDFBE_03399 5.8e-197 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EKBHDFBE_03400 6.4e-58 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
EKBHDFBE_03401 5.4e-281 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EKBHDFBE_03402 1.9e-157 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EKBHDFBE_03403 3.9e-123 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
EKBHDFBE_03404 1.1e-110 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
EKBHDFBE_03405 5.8e-222 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EKBHDFBE_03406 8.5e-137 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
EKBHDFBE_03407 3.8e-196 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EKBHDFBE_03408 2.2e-199 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
EKBHDFBE_03409 1.2e-228 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EKBHDFBE_03410 2.8e-227 S COG0457 FOG TPR repeat
EKBHDFBE_03411 1.1e-98 ypiB S Belongs to the UPF0302 family
EKBHDFBE_03412 4.8e-73 ypiF S Protein of unknown function (DUF2487)
EKBHDFBE_03413 5.1e-95 qcrA C Menaquinol-cytochrome c reductase
EKBHDFBE_03414 7.9e-128 petB C COG1290 Cytochrome b subunit of the bc complex
EKBHDFBE_03415 8.7e-147 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
EKBHDFBE_03416 8.3e-97 ypjA S membrane
EKBHDFBE_03417 2.2e-137 ypjB S sporulation protein
EKBHDFBE_03418 2.9e-218 oxdC 4.1.1.2 G Oxalate decarboxylase
EKBHDFBE_03419 1.3e-154 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
EKBHDFBE_03420 8.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
EKBHDFBE_03421 8.5e-145 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EKBHDFBE_03422 1.2e-70 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
EKBHDFBE_03423 2.7e-126 bshB1 S proteins, LmbE homologs
EKBHDFBE_03424 7.7e-208 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
EKBHDFBE_03425 1.5e-206 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EKBHDFBE_03426 6e-177 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EKBHDFBE_03427 1.6e-149 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
EKBHDFBE_03428 8.5e-151 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EKBHDFBE_03429 2.5e-62 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EKBHDFBE_03430 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
EKBHDFBE_03431 5e-23 ypmA S Protein of unknown function (DUF4264)
EKBHDFBE_03432 8.1e-74 ypmB S protein conserved in bacteria
EKBHDFBE_03433 1.1e-217 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
EKBHDFBE_03434 1.3e-248 asnS 6.1.1.22 J asparaginyl-tRNA
EKBHDFBE_03435 4.8e-128 dnaD L DNA replication protein DnaD
EKBHDFBE_03436 6e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EKBHDFBE_03437 2.1e-85 ypoC
EKBHDFBE_03438 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EKBHDFBE_03439 1.4e-110 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EKBHDFBE_03440 6.6e-176 yppC S Protein of unknown function (DUF2515)
EKBHDFBE_03443 1.5e-11 yppE S Bacterial domain of unknown function (DUF1798)
EKBHDFBE_03445 8e-50 yppG S YppG-like protein
EKBHDFBE_03446 1.6e-62 hspX O Belongs to the small heat shock protein (HSP20) family
EKBHDFBE_03447 7.9e-88 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
EKBHDFBE_03448 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
EKBHDFBE_03449 2.4e-223 yprB L RNase_H superfamily
EKBHDFBE_03451 7e-26 cotD S Inner spore coat protein D
EKBHDFBE_03452 1e-96 ypsA S Belongs to the UPF0398 family
EKBHDFBE_03453 2.2e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EKBHDFBE_03454 1.4e-212 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
EKBHDFBE_03455 1.1e-21 S YpzG-like protein
EKBHDFBE_03457 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
EKBHDFBE_03458 3.9e-284 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EKBHDFBE_03459 3.8e-94 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EKBHDFBE_03460 3.3e-231 pbuX F xanthine
EKBHDFBE_03462 2.2e-45 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
EKBHDFBE_03463 4.4e-101 J Acetyltransferase (GNAT) domain
EKBHDFBE_03464 4.8e-199 bcsA Q Naringenin-chalcone synthase
EKBHDFBE_03465 4.8e-85 ypbQ S protein conserved in bacteria
EKBHDFBE_03466 0.0 ypbR S Dynamin family
EKBHDFBE_03467 3.7e-33 ypbS S Protein of unknown function (DUF2533)
EKBHDFBE_03469 1e-159 polA 2.7.7.7 L 5'3' exonuclease
EKBHDFBE_03471 1e-66 rnhA 3.1.26.4 L Ribonuclease
EKBHDFBE_03472 5.2e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EKBHDFBE_03473 5.7e-118 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
EKBHDFBE_03474 3.6e-27 ypeQ S Zinc-finger
EKBHDFBE_03475 3e-35 S Protein of unknown function (DUF2564)
EKBHDFBE_03476 1.4e-10 degR
EKBHDFBE_03477 2.3e-30 cspD K Cold-shock protein
EKBHDFBE_03478 6.1e-213 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
EKBHDFBE_03479 1.5e-174 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EKBHDFBE_03481 1.2e-82 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
EKBHDFBE_03482 4.5e-90 ypgQ S phosphohydrolase
EKBHDFBE_03483 3.1e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
EKBHDFBE_03484 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
EKBHDFBE_03485 6.5e-75 yphP S Belongs to the UPF0403 family
EKBHDFBE_03486 9.7e-130 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
EKBHDFBE_03487 1.8e-110 ypjP S YpjP-like protein
EKBHDFBE_03488 2.5e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EKBHDFBE_03489 3e-84 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EKBHDFBE_03490 2.2e-108 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EKBHDFBE_03491 1.3e-108 hlyIII S protein, Hemolysin III
EKBHDFBE_03492 1.9e-162 pspF K Transcriptional regulator
EKBHDFBE_03493 2.1e-238 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EKBHDFBE_03494 6.7e-40 ypmP S Protein of unknown function (DUF2535)
EKBHDFBE_03495 2.7e-100 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
EKBHDFBE_03496 1.6e-129 ypmR E GDSL-like Lipase/Acylhydrolase
EKBHDFBE_03497 6.3e-94 ypmS S protein conserved in bacteria
EKBHDFBE_03498 8e-67 ypoP K transcriptional
EKBHDFBE_03499 1.9e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EKBHDFBE_03500 1.2e-76 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
EKBHDFBE_03501 5e-99 4.2.1.115 GM Polysaccharide biosynthesis protein
EKBHDFBE_03502 9.2e-245 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
EKBHDFBE_03503 2.3e-207 yxbF K Bacterial regulatory proteins, tetR family
EKBHDFBE_03504 1.3e-193 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
EKBHDFBE_03505 1.3e-191 desK 2.7.13.3 T Histidine kinase
EKBHDFBE_03506 1.4e-99 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EKBHDFBE_03507 5.5e-147 IQ Enoyl-(Acyl carrier protein) reductase
EKBHDFBE_03508 0.0 htpG O Molecular chaperone. Has ATPase activity
EKBHDFBE_03509 6.2e-244 csbC EGP Major facilitator Superfamily
EKBHDFBE_03510 2.3e-170 iolS C Aldo keto reductase
EKBHDFBE_03511 1.1e-133 iolR K COG1349 Transcriptional regulators of sugar metabolism
EKBHDFBE_03512 3.3e-280 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EKBHDFBE_03513 1.3e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
EKBHDFBE_03514 2.8e-174 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
EKBHDFBE_03515 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
EKBHDFBE_03516 1.1e-169 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
EKBHDFBE_03517 3.4e-228 iolF EGP Major facilitator Superfamily
EKBHDFBE_03518 2.7e-191 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
EKBHDFBE_03519 5.7e-163 iolH G Xylose isomerase-like TIM barrel
EKBHDFBE_03520 4.7e-154 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
EKBHDFBE_03521 1.7e-151 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
EKBHDFBE_03522 3.3e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKBHDFBE_03523 3.4e-172 T PhoQ Sensor
EKBHDFBE_03524 1.4e-139 yxdL V ABC transporter, ATP-binding protein
EKBHDFBE_03525 0.0 yxdM V ABC transporter (permease)
EKBHDFBE_03526 3.9e-54 yxeA S Protein of unknown function (DUF1093)
EKBHDFBE_03527 3.2e-170 fhuD P Periplasmic binding protein
EKBHDFBE_03528 1.3e-15
EKBHDFBE_03529 2.6e-24 yxeD
EKBHDFBE_03531 3.3e-22 yxeE
EKBHDFBE_03534 1e-145 yidA S hydrolases of the HAD superfamily
EKBHDFBE_03535 9.9e-169 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EKBHDFBE_03536 1e-111 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EKBHDFBE_03537 6.8e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EKBHDFBE_03538 6.7e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
EKBHDFBE_03539 1.7e-257 lysP E amino acid
EKBHDFBE_03540 2.6e-169 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
EKBHDFBE_03541 1.5e-228 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
EKBHDFBE_03542 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EKBHDFBE_03543 3.4e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
EKBHDFBE_03544 1.1e-77 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
EKBHDFBE_03545 5.9e-266 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
EKBHDFBE_03546 2.9e-24
EKBHDFBE_03547 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EKBHDFBE_03548 5.4e-272 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EKBHDFBE_03549 9.1e-72 yxiE T Belongs to the universal stress protein A family
EKBHDFBE_03550 2.5e-156 yxxF EG EamA-like transporter family
EKBHDFBE_03551 5.2e-198 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
EKBHDFBE_03552 0.0 wapA M COG3209 Rhs family protein
EKBHDFBE_03555 2.2e-56 yxxG
EKBHDFBE_03556 1.7e-64 yxiG
EKBHDFBE_03559 7e-27
EKBHDFBE_03560 1.2e-76
EKBHDFBE_03561 2.5e-110
EKBHDFBE_03562 7.4e-12 S YxiJ-like protein
EKBHDFBE_03563 8.8e-21
EKBHDFBE_03565 9.3e-259 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
EKBHDFBE_03566 1.3e-216 yxiO S COG2270 Permeases of the major facilitator superfamily
EKBHDFBE_03567 1.8e-142 licT K transcriptional antiterminator
EKBHDFBE_03568 5e-136 exoK GH16 M licheninase activity
EKBHDFBE_03569 5.8e-220 citH C Citrate transporter
EKBHDFBE_03570 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
EKBHDFBE_03571 1.4e-50 yxiS
EKBHDFBE_03572 2.5e-89 T Domain of unknown function (DUF4163)
EKBHDFBE_03573 6.3e-206 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EKBHDFBE_03574 1.1e-145 rlmA 2.1.1.187 Q Methyltransferase domain
EKBHDFBE_03575 3.9e-212 yxjG 2.1.1.14 E Methionine synthase
EKBHDFBE_03576 5.7e-80 yxjI S LURP-one-related
EKBHDFBE_03579 7.5e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
EKBHDFBE_03580 6.5e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EKBHDFBE_03581 9.6e-91 yxkC S Domain of unknown function (DUF4352)
EKBHDFBE_03583 1.5e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
EKBHDFBE_03584 5e-154 lrp QT PucR C-terminal helix-turn-helix domain
EKBHDFBE_03585 2.1e-202 msmK P Belongs to the ABC transporter superfamily
EKBHDFBE_03586 2.1e-149 yxkH G Polysaccharide deacetylase
EKBHDFBE_03587 2.6e-223 cimH C COG3493 Na citrate symporter
EKBHDFBE_03588 5e-265 cydA 1.10.3.14 C oxidase, subunit
EKBHDFBE_03589 9.6e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
EKBHDFBE_03590 2.7e-305 cydD V ATP-binding
EKBHDFBE_03591 7.9e-305 cydD V ATP-binding protein
EKBHDFBE_03592 7e-150 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EKBHDFBE_03593 3.4e-247 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
EKBHDFBE_03594 2.6e-184 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
EKBHDFBE_03595 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
EKBHDFBE_03596 9.2e-203 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
EKBHDFBE_03597 4.5e-177 manA 5.3.1.8 G mannose-6-phosphate isomerase
EKBHDFBE_03598 3.3e-158 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
EKBHDFBE_03599 5.3e-275 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EKBHDFBE_03600 4.7e-233 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EKBHDFBE_03601 1.4e-47 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
EKBHDFBE_03602 1.9e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
EKBHDFBE_03603 1.8e-224 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EKBHDFBE_03604 2e-50 arsR K transcriptional
EKBHDFBE_03605 3.7e-165 cbrA3 P Periplasmic binding protein
EKBHDFBE_03606 8.7e-179 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKBHDFBE_03607 4.4e-170 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKBHDFBE_03608 3e-107 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
EKBHDFBE_03609 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
EKBHDFBE_03610 1.3e-48 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
EKBHDFBE_03611 5e-246 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EKBHDFBE_03612 2.1e-49 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
EKBHDFBE_03613 2.3e-248 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EKBHDFBE_03614 5.4e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
EKBHDFBE_03615 8.8e-223 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EKBHDFBE_03616 3.2e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKBHDFBE_03617 6.5e-226 dltB M membrane protein involved in D-alanine export
EKBHDFBE_03618 5.8e-288 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKBHDFBE_03619 3.5e-12 S D-Ala-teichoic acid biosynthesis protein
EKBHDFBE_03620 1e-165 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
EKBHDFBE_03621 8.5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
EKBHDFBE_03622 4.2e-158 gspA M General stress
EKBHDFBE_03623 2e-268 epr 3.4.21.62 O Belongs to the peptidase S8 family
EKBHDFBE_03624 2.3e-243 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EKBHDFBE_03625 5.4e-65 ywbC 4.4.1.5 E glyoxalase
EKBHDFBE_03626 2.5e-217 ywbD 2.1.1.191 J Methyltransferase
EKBHDFBE_03627 3.3e-26 ywbE S Uncharacterized conserved protein (DUF2196)
EKBHDFBE_03628 7.5e-110 ywbG M effector of murein hydrolase
EKBHDFBE_03629 3.2e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
EKBHDFBE_03630 5.4e-156 ywbI K Transcriptional regulator
EKBHDFBE_03631 3e-129 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EKBHDFBE_03632 1.8e-108 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
EKBHDFBE_03633 2.8e-194 P COG0672 High-affinity Fe2 Pb2 permease
EKBHDFBE_03634 1.5e-150 ycdO P periplasmic lipoprotein involved in iron transport
EKBHDFBE_03635 1.4e-231 ywbN P Dyp-type peroxidase family protein
EKBHDFBE_03636 1.5e-106 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
EKBHDFBE_03637 4.7e-120 S Streptomycin biosynthesis protein StrF
EKBHDFBE_03638 6.3e-125 H Methionine biosynthesis protein MetW
EKBHDFBE_03640 2.3e-97 ywcC K Bacterial regulatory proteins, tetR family
EKBHDFBE_03641 6.2e-59 gtcA S GtrA-like protein
EKBHDFBE_03642 5.5e-209 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EKBHDFBE_03643 9.2e-281 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
EKBHDFBE_03644 3.7e-35 ywzA S membrane
EKBHDFBE_03645 3.9e-176 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
EKBHDFBE_03646 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EKBHDFBE_03647 3.1e-110 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
EKBHDFBE_03648 7.8e-61 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
EKBHDFBE_03649 8.5e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
EKBHDFBE_03650 1.1e-69 ysnE K acetyltransferase
EKBHDFBE_03651 7.3e-209 rodA D Belongs to the SEDS family
EKBHDFBE_03652 1e-136 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
EKBHDFBE_03653 2.1e-29 S Stress responsive A/B Barrel Domain
EKBHDFBE_03654 1.2e-41 S Ketosteroid isomerase-related protein
EKBHDFBE_03655 9.8e-125 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKBHDFBE_03656 8.4e-120 M1-869 K WYL domain
EKBHDFBE_03657 2.9e-182 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKBHDFBE_03658 0.0 vpr O Belongs to the peptidase S8 family
EKBHDFBE_03660 7e-130 sacT K transcriptional antiterminator
EKBHDFBE_03661 1.4e-248 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EKBHDFBE_03662 2.6e-269 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
EKBHDFBE_03663 3.6e-19 ywdA
EKBHDFBE_03664 5.6e-144 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
EKBHDFBE_03666 8.5e-145 ywdF GT2,GT4 S Glycosyltransferase like family 2
EKBHDFBE_03667 1.3e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EKBHDFBE_03668 8.5e-43 ywdI S Family of unknown function (DUF5327)
EKBHDFBE_03671 1.6e-63 hxlR K transcriptional
EKBHDFBE_03672 1.6e-101 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
EKBHDFBE_03673 3.1e-93 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
EKBHDFBE_03674 5.4e-77 nucA M Deoxyribonuclease NucA/NucB
EKBHDFBE_03675 1.6e-64 nin S Competence protein J (ComJ)
EKBHDFBE_03676 4.9e-284 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EKBHDFBE_03677 1.7e-48 S Protein of unknown function (DUF2680)
EKBHDFBE_03678 9.8e-71 yckC S membrane
EKBHDFBE_03679 6e-216 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EKBHDFBE_03680 2.2e-221 yciC S GTPases (G3E family)
EKBHDFBE_03681 2.1e-39 nasA P COG2223 Nitrate nitrite transporter
EKBHDFBE_03682 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EKBHDFBE_03683 1.6e-54 nirD 1.7.1.15 P Nitrite reductase
EKBHDFBE_03684 1.3e-260 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
EKBHDFBE_03685 6.4e-182 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
EKBHDFBE_03686 1.7e-224 ycgP QT COG2508 Regulator of polyketide synthase expression
EKBHDFBE_03687 3.2e-243 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EKBHDFBE_03688 2.4e-289 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
EKBHDFBE_03689 2.6e-166 ycgM E Proline dehydrogenase
EKBHDFBE_03690 1.2e-138 ycgL S Predicted nucleotidyltransferase
EKBHDFBE_03691 7.4e-180 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
EKBHDFBE_03692 4.3e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EKBHDFBE_03693 6.1e-225 G COG0477 Permeases of the major facilitator superfamily
EKBHDFBE_03694 6.9e-131 4.2.1.118 G Xylose isomerase-like TIM barrel
EKBHDFBE_03695 9.3e-147 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EKBHDFBE_03696 1.3e-110 ycgI S Domain of unknown function (DUF1989)
EKBHDFBE_03697 3.3e-231 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
EKBHDFBE_03698 1.2e-145 yqcI S YqcI/YcgG family
EKBHDFBE_03699 2.3e-113 ycgF E Lysine exporter protein LysE YggA
EKBHDFBE_03700 4.5e-74 emrR K helix_turn_helix multiple antibiotic resistance protein
EKBHDFBE_03701 8.6e-271 mdr EGP Major facilitator Superfamily
EKBHDFBE_03702 3.8e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
EKBHDFBE_03703 1.2e-13 S RDD family
EKBHDFBE_03704 7.5e-41 ycgB
EKBHDFBE_03705 1.8e-225 ycgA S Membrane
EKBHDFBE_03706 6e-205 amhX S amidohydrolase
EKBHDFBE_03707 7.1e-161 opuAC E glycine betaine
EKBHDFBE_03708 5.8e-144 opuAB P glycine betaine
EKBHDFBE_03709 4.3e-228 proV 3.6.3.32 E glycine betaine
EKBHDFBE_03711 2.5e-209 naiP P Uncharacterised MFS-type transporter YbfB
EKBHDFBE_03712 7.4e-192 yceH P Belongs to the TelA family
EKBHDFBE_03713 1.4e-303 yceG S Putative component of 'biosynthetic module'
EKBHDFBE_03714 5.7e-138 terC P Protein of unknown function (DUF475)
EKBHDFBE_03715 1.4e-104 yceE T proteins involved in stress response, homologs of TerZ and
EKBHDFBE_03716 2.4e-104 yceD T proteins involved in stress response, homologs of TerZ and
EKBHDFBE_03717 1.2e-106 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
EKBHDFBE_03718 7.7e-180 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKBHDFBE_03719 4.9e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
EKBHDFBE_03720 6.1e-131 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
EKBHDFBE_03721 2.8e-166 adcA P Belongs to the bacterial solute-binding protein 9 family
EKBHDFBE_03722 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
EKBHDFBE_03723 4.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
EKBHDFBE_03724 1.6e-173 S response regulator aspartate phosphatase
EKBHDFBE_03725 3e-87 cwlK M D-alanyl-D-alanine carboxypeptidase
EKBHDFBE_03726 5.7e-250 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
EKBHDFBE_03727 5.3e-235 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
EKBHDFBE_03728 2.5e-162 ycdA S Domain of unknown function (DUF5105)
EKBHDFBE_03729 7.3e-164 yccK C Aldo keto reductase
EKBHDFBE_03730 7.3e-192 yccF K DNA-templated transcriptional preinitiation complex assembly
EKBHDFBE_03731 3.5e-109 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
EKBHDFBE_03732 3.9e-96 yxaF K Transcriptional regulator
EKBHDFBE_03733 1.3e-241 lmrB EGP the major facilitator superfamily
EKBHDFBE_03734 6.9e-193 ycbU E Selenocysteine lyase
EKBHDFBE_03735 4.9e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EKBHDFBE_03736 2.4e-122 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EKBHDFBE_03737 4.8e-25 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EKBHDFBE_03738 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
EKBHDFBE_03739 1.4e-77 sleB 3.5.1.28 M Cell wall
EKBHDFBE_03740 5.6e-62 ycbP S Protein of unknown function (DUF2512)
EKBHDFBE_03741 1.8e-56 traF CO Thioredoxin
EKBHDFBE_03742 6.7e-63 mhqP S DoxX
EKBHDFBE_03743 1.3e-181 ydfO E COG0346 Lactoylglutathione lyase and related lyases
EKBHDFBE_03744 4e-110 ydfN C nitroreductase
EKBHDFBE_03745 8.5e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EKBHDFBE_03746 1.3e-23 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
EKBHDFBE_03747 1.2e-123 ycbJ S Macrolide 2'-phosphotransferase
EKBHDFBE_03748 5.3e-154 glnL T Regulator
EKBHDFBE_03749 3.1e-205 phoQ 2.7.13.3 T Histidine kinase
EKBHDFBE_03750 2.5e-186 glsA 3.5.1.2 E Belongs to the glutaminase family
EKBHDFBE_03751 1.5e-253 agcS E Sodium alanine symporter
EKBHDFBE_03752 1.6e-174 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
EKBHDFBE_03753 1.8e-249 mmuP E amino acid
EKBHDFBE_03754 3.8e-193 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
EKBHDFBE_03755 5e-208 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EKBHDFBE_03756 3.2e-186 yceA S Belongs to the UPF0176 family
EKBHDFBE_03757 1.5e-37 ybfN
EKBHDFBE_03758 3.7e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
EKBHDFBE_03759 3.9e-84 ybfM S SNARE associated Golgi protein
EKBHDFBE_03760 9.5e-92 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EKBHDFBE_03761 9.2e-209 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EKBHDFBE_03762 1.7e-188 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
EKBHDFBE_03763 1.5e-80 K Helix-turn-helix XRE-family like proteins
EKBHDFBE_03764 6.3e-91 ywqJ S LXG domain of WXG superfamily
EKBHDFBE_03765 1.4e-17
EKBHDFBE_03766 2.5e-123 ybfI K AraC-like ligand binding domain
EKBHDFBE_03767 4.7e-115 ybfH EG EamA-like transporter family
EKBHDFBE_03768 3e-10 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
EKBHDFBE_03769 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
EKBHDFBE_03771 1.8e-206 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
EKBHDFBE_03772 1.3e-16 S Protein of unknown function (DUF2651)
EKBHDFBE_03773 9.5e-258 glpT G -transporter
EKBHDFBE_03774 1.3e-162 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
EKBHDFBE_03775 2.3e-16 S Protein of unknown function (DUF2651)
EKBHDFBE_03776 2.9e-56
EKBHDFBE_03777 5.3e-48 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EKBHDFBE_03778 2.3e-306 ybeC E amino acid
EKBHDFBE_03779 1.3e-38 ybyB
EKBHDFBE_03780 2e-105 yqeB
EKBHDFBE_03781 1.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
EKBHDFBE_03782 2.4e-78 S Domain of unknown function (DUF4879)
EKBHDFBE_03783 1.4e-23
EKBHDFBE_03784 5.2e-180 V ABC-2 family transporter protein
EKBHDFBE_03785 2.2e-189 V COG0842 ABC-type multidrug transport system, permease component
EKBHDFBE_03786 7.1e-159 V COG1131 ABC-type multidrug transport system, ATPase component
EKBHDFBE_03787 8.7e-100 KT LuxR family transcriptional regulator
EKBHDFBE_03788 3.8e-183 T COG4585 Signal transduction histidine kinase
EKBHDFBE_03789 6.7e-93 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
EKBHDFBE_03790 1.5e-253 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
EKBHDFBE_03791 4.5e-68 yxaD K helix_turn_helix multiple antibiotic resistance protein
EKBHDFBE_03792 9.9e-51 S LrgA family
EKBHDFBE_03793 6.3e-104 yxaC M effector of murein hydrolase
EKBHDFBE_03794 2.6e-152 dkgB S Aldo/keto reductase family
EKBHDFBE_03795 6.7e-92 H Tellurite resistance protein TehB
EKBHDFBE_03797 1.1e-273 KLT Protein kinase domain
EKBHDFBE_03798 2e-99 S ABC-2 family transporter protein
EKBHDFBE_03799 1.1e-145 V ATPases associated with a variety of cellular activities
EKBHDFBE_03800 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EKBHDFBE_03801 2.8e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EKBHDFBE_03802 1.2e-229 ybbR S protein conserved in bacteria
EKBHDFBE_03803 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EKBHDFBE_03804 8.7e-113 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
EKBHDFBE_03805 1.6e-97 sigW K Belongs to the sigma-70 factor family. ECF subfamily
EKBHDFBE_03811 1.5e-74 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
EKBHDFBE_03812 1.1e-80 ybbJ J acetyltransferase
EKBHDFBE_03813 3.7e-160 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EKBHDFBE_03814 9.5e-237 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EKBHDFBE_03815 8.3e-235 yfeW 3.4.16.4 V Belongs to the UPF0214 family
EKBHDFBE_03816 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
EKBHDFBE_03817 9.5e-228 ybbC 3.2.1.52 S protein conserved in bacteria
EKBHDFBE_03818 1.6e-291 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
EKBHDFBE_03819 8.5e-168 feuA P Iron-uptake system-binding protein
EKBHDFBE_03820 1.5e-175 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKBHDFBE_03821 7.7e-175 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKBHDFBE_03822 1.1e-98 ybbA S Putative esterase
EKBHDFBE_03823 2.3e-168 ybaS 1.1.1.58 S Na -dependent transporter
EKBHDFBE_03824 6.2e-223 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
EKBHDFBE_03825 1e-198 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
EKBHDFBE_03826 1.5e-177 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
EKBHDFBE_03827 3.7e-243 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EKBHDFBE_03828 2.5e-212 glcP G Major Facilitator Superfamily
EKBHDFBE_03832 3.2e-170 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EKBHDFBE_03833 2.9e-84 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
EKBHDFBE_03834 1.5e-121 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
EKBHDFBE_03835 3.4e-82 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
EKBHDFBE_03836 1.8e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EKBHDFBE_03837 0.0 ydiF S ABC transporter
EKBHDFBE_03838 1.9e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
EKBHDFBE_03839 1.6e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EKBHDFBE_03840 1.1e-20 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EKBHDFBE_03841 5e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EKBHDFBE_03842 5e-27 ydiK S Domain of unknown function (DUF4305)
EKBHDFBE_03843 3.1e-125 ydiL S CAAX protease self-immunity
EKBHDFBE_03844 9.6e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EKBHDFBE_03845 2.9e-285 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EKBHDFBE_03846 7.6e-151 ydjC S Abhydrolase domain containing 18
EKBHDFBE_03847 0.0 K NB-ARC domain
EKBHDFBE_03848 2e-197 gutB 1.1.1.14 E Dehydrogenase
EKBHDFBE_03849 1.9e-245 gutA G MFS/sugar transport protein
EKBHDFBE_03850 9.2e-170 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
EKBHDFBE_03851 6.1e-30 yjdJ S Domain of unknown function (DUF4306)
EKBHDFBE_03852 1.2e-110 pspA KT Phage shock protein A
EKBHDFBE_03853 2.5e-173 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EKBHDFBE_03854 3.6e-121 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
EKBHDFBE_03855 1.6e-156 ydjI S virion core protein (lumpy skin disease virus)
EKBHDFBE_03856 0.0 yrhL I Acyltransferase family
EKBHDFBE_03857 1.6e-144 rsiV S Protein of unknown function (DUF3298)
EKBHDFBE_03858 2.1e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
EKBHDFBE_03859 1.6e-191 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
EKBHDFBE_03860 1.9e-62 ydjM M Lytic transglycolase
EKBHDFBE_03861 2.2e-148 ydjN U Involved in the tonB-independent uptake of proteins
EKBHDFBE_03863 4.1e-34 ydjO S Cold-inducible protein YdjO
EKBHDFBE_03864 5.7e-299 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
EKBHDFBE_03865 4.9e-241 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
EKBHDFBE_03866 4e-140 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EKBHDFBE_03867 8.6e-176 yeaC S COG0714 MoxR-like ATPases
EKBHDFBE_03868 1.8e-199 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
EKBHDFBE_03869 0.0 yebA E COG1305 Transglutaminase-like enzymes
EKBHDFBE_03870 3.2e-297 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
EKBHDFBE_03871 1.4e-90 sigV K Belongs to the sigma-70 factor family. ECF subfamily
EKBHDFBE_03872 1.5e-248 S Domain of unknown function (DUF4179)
EKBHDFBE_03873 3.9e-211 pbuG S permease
EKBHDFBE_03874 1.4e-128 yebC M Membrane
EKBHDFBE_03876 5.8e-92 yebE S UPF0316 protein
EKBHDFBE_03877 6e-28 yebG S NETI protein
EKBHDFBE_03878 4.8e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EKBHDFBE_03879 1.8e-220 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EKBHDFBE_03880 2.3e-245 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EKBHDFBE_03881 7.2e-127 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
EKBHDFBE_03882 2.4e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EKBHDFBE_03883 2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EKBHDFBE_03884 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EKBHDFBE_03885 5.4e-267 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EKBHDFBE_03886 5.6e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
EKBHDFBE_03887 1.6e-100 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EKBHDFBE_03888 2.3e-284 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
EKBHDFBE_03889 7.2e-231 purD 6.3.4.13 F Belongs to the GARS family
EKBHDFBE_03890 1.4e-61 K helix_turn_helix ASNC type
EKBHDFBE_03891 4.8e-139 yjeH E Amino acid permease
EKBHDFBE_03892 2.8e-24 S Protein of unknown function (DUF2892)
EKBHDFBE_03893 0.0 yerA 3.5.4.2 F adenine deaminase
EKBHDFBE_03894 5.9e-188 yerB S Protein of unknown function (DUF3048) C-terminal domain
EKBHDFBE_03895 2.3e-50 yerC S protein conserved in bacteria
EKBHDFBE_03896 1.6e-296 yerD 1.4.7.1 E Belongs to the glutamate synthase family
EKBHDFBE_03897 7.6e-126 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EKBHDFBE_03898 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
EKBHDFBE_03899 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EKBHDFBE_03900 4e-223 camS S COG4851 Protein involved in sex pheromone biosynthesis
EKBHDFBE_03901 2.3e-179 yerI S homoserine kinase type II (protein kinase fold)
EKBHDFBE_03902 2.1e-120 sapB S MgtC SapB transporter
EKBHDFBE_03903 3.7e-263 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EKBHDFBE_03904 2.3e-44 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EKBHDFBE_03905 1.1e-272 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EKBHDFBE_03906 7.5e-269 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EKBHDFBE_03907 5.7e-147 yerO K Transcriptional regulator
EKBHDFBE_03908 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EKBHDFBE_03909 1.6e-168 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EKBHDFBE_03910 7.8e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EKBHDFBE_03911 1.4e-129
EKBHDFBE_03912 6e-114 cll
EKBHDFBE_03913 7.4e-36 S Plasmid maintenance system killer
EKBHDFBE_03914 5.9e-133 higA K Pfam:DUF955
EKBHDFBE_03916 6e-61 S Protein of unknown function, DUF600
EKBHDFBE_03917 1.5e-75 S Protein of unknown function, DUF600
EKBHDFBE_03918 3.6e-79 S Protein of unknown function, DUF600
EKBHDFBE_03919 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
EKBHDFBE_03920 2.3e-125 yeeN K transcriptional regulatory protein
EKBHDFBE_03922 9e-108 aadK G Streptomycin adenylyltransferase
EKBHDFBE_03923 9e-45 cotJA S Spore coat associated protein JA (CotJA)
EKBHDFBE_03924 7.3e-45 cotJB S CotJB protein
EKBHDFBE_03925 3.7e-102 cotJC P Spore Coat
EKBHDFBE_03926 3.8e-85 yesJ K Acetyltransferase (GNAT) family
EKBHDFBE_03928 3.9e-114 yetF S membrane
EKBHDFBE_03929 4.5e-52 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
EKBHDFBE_03930 4.1e-62 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EKBHDFBE_03931 3.5e-144 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EKBHDFBE_03932 6.4e-21 yezD S Uncharacterized small protein (DUF2292)
EKBHDFBE_03933 3.4e-54 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
EKBHDFBE_03934 2e-104 yetJ S Belongs to the BI1 family
EKBHDFBE_03935 9.1e-84 yetL K helix_turn_helix multiple antibiotic resistance protein
EKBHDFBE_03936 2.4e-193 yetM CH FAD binding domain
EKBHDFBE_03937 1.4e-195 yetN S Protein of unknown function (DUF3900)
EKBHDFBE_03938 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
EKBHDFBE_03940 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
EKBHDFBE_03941 2.4e-144 rfbF 2.7.7.33 JM Nucleotidyl transferase
EKBHDFBE_03942 4.6e-171 yfnG 4.2.1.45 M dehydratase
EKBHDFBE_03943 1.1e-172 yfnF M Nucleotide-diphospho-sugar transferase
EKBHDFBE_03944 1.5e-211 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
EKBHDFBE_03945 1.7e-176 yfnD M Nucleotide-diphospho-sugar transferase
EKBHDFBE_03946 2.5e-212 fsr P COG0477 Permeases of the major facilitator superfamily
EKBHDFBE_03947 1.6e-239 yfnA E amino acid
EKBHDFBE_03948 5.5e-275 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EKBHDFBE_03949 9.1e-129 yfmS NT chemotaxis protein
EKBHDFBE_03950 2.4e-164 IQ Enoyl-(Acyl carrier protein) reductase
EKBHDFBE_03951 1.5e-200 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EKBHDFBE_03952 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EKBHDFBE_03953 2.2e-67 yfmP K transcriptional
EKBHDFBE_03954 2e-195 yfmO EGP Major facilitator Superfamily
EKBHDFBE_03955 8.1e-293 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EKBHDFBE_03956 2.5e-203 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
EKBHDFBE_03957 1.5e-178 yfmJ S N-terminal domain of oxidoreductase
EKBHDFBE_03958 3.2e-24 S Protein of unknown function (DUF3212)
EKBHDFBE_03959 3.8e-57 yflT S Heat induced stress protein YflT
EKBHDFBE_03960 4.1e-234 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
EKBHDFBE_03961 4.6e-250 yflS P Sodium:sulfate symporter transmembrane region
EKBHDFBE_03962 7.3e-26 Q PFAM Collagen triple helix
EKBHDFBE_03964 5.5e-48 S SMI1-KNR4 cell-wall
EKBHDFBE_03965 5.1e-206 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
EKBHDFBE_03966 4.9e-54
EKBHDFBE_03967 1.2e-75 K Transcriptional regulator
EKBHDFBE_03968 1.2e-96 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EKBHDFBE_03969 8.6e-30 cspL K Cold shock
EKBHDFBE_03970 8.1e-17 S Protein of unknown function (DUF3888)
EKBHDFBE_03971 3.1e-69 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
EKBHDFBE_03972 1.5e-110 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
EKBHDFBE_03973 2.7e-100 S Protein of unknown function (DUF2812)
EKBHDFBE_03974 1.7e-48 K Transcriptional regulator PadR-like family
EKBHDFBE_03975 3.1e-235 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EKBHDFBE_03976 4.5e-188 ydeG EGP Major facilitator superfamily
EKBHDFBE_03977 1.1e-170 S Patatin-like phospholipase
EKBHDFBE_03979 3.9e-251 ygaK C COG0277 FAD FMN-containing dehydrogenases
EKBHDFBE_03980 7.3e-71 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EKBHDFBE_03981 3.8e-152 czcD P COG1230 Co Zn Cd efflux system component
EKBHDFBE_03982 3.1e-151 S SNARE associated Golgi protein
EKBHDFBE_03983 1.2e-94 yrkC G Cupin domain
EKBHDFBE_03984 2.5e-81 yyaR K Acetyltransferase (GNAT) domain
EKBHDFBE_03985 3.8e-146 ydeE K AraC family transcriptional regulator
EKBHDFBE_03987 1.1e-187 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
EKBHDFBE_03988 7.1e-47 ydeH
EKBHDFBE_03989 3.2e-162 S Sodium Bile acid symporter family
EKBHDFBE_03990 6.2e-196 adhA 1.1.1.1 C alcohol dehydrogenase
EKBHDFBE_03991 5.5e-60 yraB K helix_turn_helix, mercury resistance
EKBHDFBE_03992 1.6e-217 mleN_2 C antiporter
EKBHDFBE_03993 3.5e-247 K helix_turn_helix gluconate operon transcriptional repressor
EKBHDFBE_03994 2e-101 paiB K Transcriptional regulator
EKBHDFBE_03995 2.7e-187 ydeR EGP Major facilitator Superfamily
EKBHDFBE_03996 1.7e-99 ydeS K Transcriptional regulator
EKBHDFBE_03997 8.2e-149 ydeK EG -transporter
EKBHDFBE_03998 1.3e-249 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EKBHDFBE_03999 1.2e-46 yraD M Spore coat protein
EKBHDFBE_04000 1.1e-24 yraE
EKBHDFBE_04001 5.3e-217 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EKBHDFBE_04002 1.1e-62 yraF M Spore coat protein
EKBHDFBE_04003 6.4e-35 yraG
EKBHDFBE_04004 4.2e-127 puuD S Peptidase C26
EKBHDFBE_04005 5.9e-286 expZ S ABC transporter
EKBHDFBE_04006 3.9e-90 ynaD J Acetyltransferase (GNAT) domain
EKBHDFBE_04007 3.9e-148 S Uncharacterized protein conserved in bacteria (DUF2179)
EKBHDFBE_04008 2.8e-194 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
EKBHDFBE_04009 9e-207 tcaB EGP Major facilitator Superfamily
EKBHDFBE_04010 1.5e-27 tnpB L Belongs to the 'phage' integrase family
EKBHDFBE_04011 2.6e-200 recN L DNA synthesis involved in DNA repair
EKBHDFBE_04013 6.5e-162 ygxA S Nucleotidyltransferase-like
EKBHDFBE_04014 7.2e-56 ygzB S UPF0295 protein
EKBHDFBE_04015 5.8e-79 perR P Belongs to the Fur family
EKBHDFBE_04016 1.9e-83 bcp 1.11.1.15 O Peroxiredoxin
EKBHDFBE_04017 3.2e-242 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
EKBHDFBE_04018 1.7e-185 ygaE S Membrane
EKBHDFBE_04019 0.0 ygaD V ABC transporter
EKBHDFBE_04020 1.4e-103 ygaC J Belongs to the UPF0374 family
EKBHDFBE_04021 1.6e-36 ygaB S YgaB-like protein
EKBHDFBE_04023 2.9e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKBHDFBE_04024 3.1e-36 yfhS
EKBHDFBE_04025 1e-201 mutY L A G-specific
EKBHDFBE_04026 1.9e-178 yfhP S membrane-bound metal-dependent
EKBHDFBE_04027 0.0 yfhO S Bacterial membrane protein YfhO
EKBHDFBE_04028 5.6e-183 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EKBHDFBE_04029 7.2e-166 yfhM S Alpha/beta hydrolase family
EKBHDFBE_04030 3.2e-37 yfhL S SdpI/YhfL protein family
EKBHDFBE_04031 2.6e-86 batE T Bacterial SH3 domain homologues
EKBHDFBE_04032 2.4e-43 yfhJ S WVELL protein
EKBHDFBE_04033 1.1e-159 mpr 3.4.21.19 M Belongs to the peptidase S1B family
EKBHDFBE_04035 7.3e-209 yfhI EGP Major facilitator Superfamily
EKBHDFBE_04036 6.7e-45 yfhH S Protein of unknown function (DUF1811)
EKBHDFBE_04037 8.4e-137 recX 2.4.1.337 GT4 S Modulates RecA activity
EKBHDFBE_04038 2.3e-162 yfhF S nucleoside-diphosphate sugar epimerase
EKBHDFBE_04040 1.9e-23 yfhD S YfhD-like protein
EKBHDFBE_04041 2.9e-102 yfhC C nitroreductase
EKBHDFBE_04042 1.1e-148 yfhB 5.3.3.17 S PhzF family
EKBHDFBE_04043 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EKBHDFBE_04044 1.6e-77 yfiV K transcriptional
EKBHDFBE_04045 8.3e-285 yfiU EGP Major facilitator Superfamily
EKBHDFBE_04046 2.1e-94 yfiT S Belongs to the metal hydrolase YfiT family
EKBHDFBE_04047 3.7e-44 yrdF K ribonuclease inhibitor
EKBHDFBE_04048 7.4e-176 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EKBHDFBE_04049 5.3e-99 1.6.5.2 S NADPH-dependent FMN reductase
EKBHDFBE_04050 7.5e-92 padR K transcriptional
EKBHDFBE_04051 6.7e-165 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EKBHDFBE_04052 5.3e-153 yfiE 1.13.11.2 S glyoxalase
EKBHDFBE_04053 5.9e-62 mhqP S DoxX
EKBHDFBE_04054 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
EKBHDFBE_04055 1.4e-301 yfiB3 V ABC transporter
EKBHDFBE_04056 0.0 yobO M COG5434 Endopolygalacturonase
EKBHDFBE_04057 1.8e-292 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EKBHDFBE_04058 1.6e-137 glvR F Helix-turn-helix domain, rpiR family
EKBHDFBE_04059 1.4e-256 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EKBHDFBE_04060 3.2e-15 sspH S Belongs to the SspH family
EKBHDFBE_04061 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
EKBHDFBE_04062 5.4e-240 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EKBHDFBE_04063 1.3e-205 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EKBHDFBE_04064 8.3e-185 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EKBHDFBE_04065 2.3e-184 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EKBHDFBE_04066 5e-78 yfjM S Psort location Cytoplasmic, score
EKBHDFBE_04067 1.8e-187 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EKBHDFBE_04068 2.3e-44 S YfzA-like protein
EKBHDFBE_04069 1.6e-191 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)