# emapper version: emapper-2.0.1b-2-g816e190 emapper DB: 2.0 # command: ./emapper.py -i Bifidobacterium_bifidum/1.contigAnn/FFN/A00000009.ffn --translate --temp_dir Bifidobacterium_bifidum/4.eggNOG_mapper --output_dir Bifidobacterium_bifidum/4.eggNOG_mapper --output A00000009 --cpu 36 --keep_mapping_files -m diamond # time: Tue May 31 11:46:33 2022 #query_name seed_eggNOG_ortholog seed_ortholog_evalue seed_ortholog_score best_tax_level Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction taxonomic scope eggNOG OGs best eggNOG OG COG Functional cat. eggNOG free text desc. LPKNPDNH_00001 398513.BBNG_01740 5.4e-189 666.8 Bifidobacteriales MA20_16500 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GKTT@201174,4CZRS@85004,COG0111@1,COG0111@2 NA|NA|NA EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family LPKNPDNH_00002 398513.BBNG_01739 1.3e-154 552.4 Bifidobacteriales sapF ko:K02032,ko:K19230 ko01503,ko02010,ko02024,map01503,map02010,map02024 M00239,M00739 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.5 Bacteria 2GP46@201174,4CYXD@85004,COG4608@1,COG4608@2 NA|NA|NA E ATPases associated with a variety of cellular activities LPKNPDNH_00003 398513.BBNG_01738 2.6e-141 508.1 Bifidobacteriales oppD ko:K02031 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GIXV@201174,4CZ3U@85004,COG0444@1,COG0444@2 NA|NA|NA EP oligopeptide transport protein of the ABC superfamily, ATP-binding component LPKNPDNH_00004 702459.BBPR_1349 1.6e-161 575.5 Bifidobacteriales ko:K02034 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GNQ5@201174,4CZ84@85004,COG1173@1,COG1173@2 NA|NA|NA EP Binding-protein-dependent transport system inner membrane component LPKNPDNH_00005 398513.BBNG_01736 4.6e-169 600.5 Bifidobacteriales ko:K02033 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GK0Z@201174,4CYST@85004,COG0601@1,COG0601@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component LPKNPDNH_00006 398513.BBNG_01735 1.3e-309 1068.1 Bifidobacteriales ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GJ4B@201174,4CYWF@85004,COG0747@1,COG0747@2 NA|NA|NA E ABC transporter, substrate-binding protein, family 5 LPKNPDNH_00007 398513.BBNG_01734 3.6e-143 514.2 Bifidobacteriales coaX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1986 Bacteria 2GMRQ@201174,4CZQS@85004,COG1521@1,COG1521@2 NA|NA|NA H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis LPKNPDNH_00008 702459.BBPR_1353 1.7e-276 958.0 Bifidobacteriales ko:K02027 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 2GJIP@201174,4CYRE@85004,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein LPKNPDNH_00009 398513.BBNG_01732 2.3e-65 255.0 Bacteria ko:K02027 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria COG1653@1,COG1653@2 NA|NA|NA G carbohydrate transport LPKNPDNH_00010 398513.BBNG_01731 0.0 1452.6 Bifidobacteriales lacZ5 3.2.1.23 ko:K12308 ko00052,map00052 R01105 RC00452 ko00000,ko00001,ko01000 Bacteria 2GMDT@201174,4CZ38@85004,COG1874@1,COG1874@2 NA|NA|NA G Psort location Cytoplasmic, score 8.87 LPKNPDNH_00011 398513.BBNG_01730 2.5e-124 451.4 Bifidobacteriales ko:K02026 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 2GJPZ@201174,4CYV5@85004,COG0395@1,COG0395@2 NA|NA|NA G ABC transporter permease LPKNPDNH_00012 702459.BBPR_1358 2.9e-190 671.0 Bifidobacteriales ko:K02529 ko00000,ko03000 Bacteria 2GK1X@201174,4CZWK@85004,COG1609@1,COG1609@2 NA|NA|NA K Periplasmic binding protein domain LPKNPDNH_00013 1437609.BCAL_0460 8.5e-20 102.8 Bifidobacteriales ghrA Bacteria 2GP09@201174,4CZUN@85004,COG0111@1,COG0111@2 NA|NA|NA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LPKNPDNH_00014 702459.BBPR_1360 0.0 2822.7 Bifidobacteriales 3.2.1.51 ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 GH29 Bacteria 2I650@201174,4CZPN@85004,COG3669@1,COG3669@2 NA|NA|NA G Alpha-L-fucosidase LPKNPDNH_00015 398513.BBNG_01757 3.3e-22 110.9 Bifidobacteriales Bacteria 2H4CW@201174,4D25Y@85004,COG2826@1,COG2826@2 NA|NA|NA L Helix-turn-helix domain LPKNPDNH_00016 702459.BBPR_0014 3.4e-18 97.4 Bifidobacteriales Bacteria 29Y3N@1,2H7EI@201174,30JWQ@2,4D2DI@85004 NA|NA|NA S Protein of unknown function (DUF2442) LPKNPDNH_00017 762211.BSTEL_0947 2.6e-16 90.9 Actinobacteria Bacteria 29ZI4@1,2GWTX@201174,30MI7@2 NA|NA|NA K Helix-turn-helix domain LPKNPDNH_00018 764298.STRMA_0402 2.9e-107 395.2 Bacilli Bacteria 1TQXV@1239,4HD04@91061,COG4974@1,COG4974@2 NA|NA|NA L Belongs to the 'phage' integrase family LPKNPDNH_00019 1507.HMPREF0262_00040 1.3e-49 203.8 Clostridia 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 1V3BB@1239,24FZ4@186801,COG0732@1,COG0732@2 NA|NA|NA V Type I restriction modification DNA specificity domain LPKNPDNH_00020 471855.Shel_17670 5.2e-244 850.1 Coriobacteriia hsdM 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 2GKAQ@201174,4CURP@84998,COG0286@1,COG0286@2 NA|NA|NA V HsdM N-terminal domain LPKNPDNH_00021 471855.Shel_17680 0.0 1689.9 Coriobacteriia hsdR 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 2HI69@201174,4CVYG@84998,COG0610@1,COG0610@2 NA|NA|NA L Subunit R is required for both nuclease and ATPase activities, but not for modification LPKNPDNH_00022 398513.BBNG_01725 0.0 2274.6 Bifidobacteriales ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GK9M@201174,4CYT7@85004,COG0060@1,COG0060@2 NA|NA|NA J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) LPKNPDNH_00023 702459.BBPR_1363 3.8e-55 220.7 Bifidobacteriales yvlD ko:K08972 ko00000 Bacteria 2HZND@201174,4D117@85004,COG1950@1,COG1950@2 NA|NA|NA S Mycobacterial 4 TMS phage holin, superfamily IV LPKNPDNH_00024 702459.BBPR_1364 3e-273 947.2 Bifidobacteriales aldH 1.2.1.3,1.2.1.5 ko:K00128,ko:K00129 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00350,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00980,ko00981,ko00982,ko01100,ko01110,ko01120,ko01130,ko05204,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00350,map00360,map00380,map00410,map00561,map00620,map00625,map00903,map00980,map00981,map00982,map01100,map01110,map01120,map01130,map05204 M00135 R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02536,R02537,R02549,R02678,R02695,R02697,R02940,R02957,R03283,R03300,R03302,R03869,R04065,R04506,R04882,R04883,R04888,R04889,R04891,R04892,R04903,R04996,R05050,R05237,R05238,R05286,R06366,R07104,R08146,R08282,R08283,R08307 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500,RC01735 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIWZ@201174,4CZQF@85004,COG1012@1,COG1012@2 NA|NA|NA C Aldehyde dehydrogenase family LPKNPDNH_00025 702459.BBPR_1365 1.8e-127 462.2 Bifidobacteriales XK27_08050 Bacteria 2GJ1U@201174,4CYTU@85004,COG0330@1,COG0330@2 NA|NA|NA O prohibitin homologues LPKNPDNH_00026 398513.BBNG_01721 2.2e-243 847.8 Bifidobacteriales 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 Bacteria 2I8JG@201174,4CZ6W@85004,COG2873@1,COG2873@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme LPKNPDNH_00027 398513.BBNG_01720 4.1e-231 807.0 Bifidobacteriales metC 4.4.1.8 ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ5S@201174,4CZKK@85004,COG0626@1,COG0626@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme LPKNPDNH_00028 398513.BBNG_01719 4.7e-260 903.3 Bifidobacteriales nox 1.6.3.4 ko:K17869 ko00000,ko01000 Bacteria 2H7WY@201174,4CZXP@85004,COG0446@1,COG0446@2 NA|NA|NA C Pyridine nucleotide-disulphide oxidoreductase LPKNPDNH_00029 702459.BBPR_1369 8.1e-227 792.7 Bifidobacteriales glxK GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 R08572 RC00002,RC00428 ko00000,ko00001,ko01000 Bacteria 2GKHX@201174,4CZRH@85004,COG1929@1,COG1929@2 NA|NA|NA G Belongs to the glycerate kinase type-1 family LPKNPDNH_00030 702459.BBPR_1370 0.0 1709.1 Bifidobacteriales macB_2 ko:K02003,ko:K02004,ko:K05685 ko02010,map02010 M00258,M00709 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.122.1,3.A.1.122.12 Bacteria 2GK3I@201174,4D0AY@85004,COG0577@1,COG0577@2,COG1136@1,COG1136@2 NA|NA|NA V ATPases associated with a variety of cellular activities LPKNPDNH_00031 702459.BBPR_1371 0.0 1486.1 Bifidobacteriales ctpE ko:K12952 ko00000,ko01000 3.A.3.23 Bacteria 2GJJC@201174,4D07Z@85004,COG0474@1,COG0474@2 NA|NA|NA P E1-E2 ATPase LPKNPDNH_00032 702459.BBPR_1372 3.6e-93 347.4 Bifidobacteriales ko:K03830 ko00000,ko01000 Bacteria 2IB9K@201174,4D0M3@85004,COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase LPKNPDNH_00033 702459.BBPR_1373 1.7e-79 302.0 Bifidobacteriales Bacteria 2H8SZ@201174,4D2D2@85004,COG0477@1,COG2814@2 NA|NA|NA EGP Major Facilitator Superfamily LPKNPDNH_00034 702459.BBPR_1374 7.1e-197 693.0 Bifidobacteriales yghZ ko:K19265 ko00000,ko01000 Bacteria 2GMT5@201174,4CZ25@85004,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family LPKNPDNH_00035 398513.BBNG_01713 5.1e-101 373.6 Bifidobacteriales dnaQ 2.7.7.7 ko:K02342,ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2I2FU@201174,4D10C@85004,COG2176@1,COG2176@2 NA|NA|NA L Exonuclease, DNA polymerase III, epsilon subunit family LPKNPDNH_00036 398513.BBNG_01712 1.1e-250 872.1 Bifidobacteriales gltA GO:0003674,GO:0003824,GO:0004108,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019752,GO:0036440,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046912,GO:0055114,GO:0071704,GO:0071944,GO:0072350 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 iIT341.HP0026,iYL1228.KPN_00727 Bacteria 2GJ7E@201174,4CZ2J@85004,COG0372@1,COG0372@2 NA|NA|NA C Citrate synthase, C-terminal domain LPKNPDNH_00037 398513.BBNG_01711 1.1e-149 535.8 Bifidobacteriales map 3.4.11.18 ko:K01265 ko00000,ko01000,ko01002 Bacteria 2GKKB@201174,4CZAA@85004,COG0024@1,COG0024@2 NA|NA|NA E Methionine aminopeptidase LPKNPDNH_00038 398513.BBNG_01710 1.5e-121 442.6 Bifidobacteriales Bacteria 2H3AT@201174,4D00R@85004,COG3247@1,COG3247@2 NA|NA|NA S Short repeat of unknown function (DUF308) LPKNPDNH_00039 702459.BBPR_1379 0.0 1414.4 Bifidobacteriales pepO 3.4.24.71 ko:K01415,ko:K07386 ko00000,ko01000,ko01002,ko04147 Bacteria 2GNJY@201174,4CYVU@85004,COG3590@1,COG3590@2 NA|NA|NA O Peptidase family M13 LPKNPDNH_00040 398513.BBNG_01708 2.1e-97 361.7 Bifidobacteriales ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 2GQIQ@201174,4D17E@85004,COG0629@1,COG0629@2 NA|NA|NA L Single-strand binding protein family LPKNPDNH_00041 702459.BBPR_1381 2.4e-170 604.7 Bifidobacteriales Bacteria 2B89A@1,2H5K4@201174,321HX@2,4D293@85004 NA|NA|NA LPKNPDNH_00042 702459.BBPR_1382 0.0 1212.2 Bifidobacteriales proS GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GJ9G@201174,4CZ6E@85004,COG0442@1,COG0442@2 NA|NA|NA J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS LPKNPDNH_00045 702459.BBPR_1386 3e-270 937.2 Bifidobacteriales recD2 3.6.4.12 ko:K15255 ko00000,ko01000,ko03029,ko03032 Bacteria 2HFY1@201174,4CZ0C@85004,COG0507@1,COG0507@2 NA|NA|NA L PIF1-like helicase LPKNPDNH_00046 702459.BBPR_1387 9e-161 572.8 Bifidobacteriales supH Bacteria 2HZBZ@201174,4CZNM@85004,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase LPKNPDNH_00047 398513.BBNG_01703 2.8e-122 444.5 Bifidobacteriales orn GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360 ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 2GJR7@201174,4CYZY@85004,COG1949@1,COG1949@2 NA|NA|NA L 3'-to-5' exoribonuclease specific for small oligoribonucleotides LPKNPDNH_00048 702459.BBPR_1389 2.7e-56 224.9 Bifidobacteriales Bacteria 2GN73@201174,4D0E2@85004,COG0745@1,COG0745@2 NA|NA|NA KT Transcriptional regulatory protein, C terminal LPKNPDNH_00049 702459.BBPR_1390 0.0 1251.9 Bifidobacteriales 3.2.1.10,3.2.1.20,3.2.1.93 ko:K01182,ko:K01187,ko:K01226 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R00837,R01718,R01791,R06087,R06088,R06113,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13,GH31 Bacteria 2GKS4@201174,4CZ1E@85004,COG0366@1,COG0366@2 NA|NA|NA G Alpha-amylase domain LPKNPDNH_00050 398513.BBNG_01700 3.5e-288 996.9 Bifidobacteriales guaB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006183,GO:0006195,GO:0006204,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009125,GO:0009126,GO:0009127,GO:0009128,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009154,GO:0009156,GO:0009158,GO:0009161,GO:0009163,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009169,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009261,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046037,GO:0046039,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GITZ@201174,4CZ2S@85004,COG0516@1,COG0516@2,COG0517@1,COG0517@2 NA|NA|NA F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth LPKNPDNH_00051 398513.BBNG_01699 6.2e-192 676.8 Bifidobacteriales tagO GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 ko:K02851 R08856 RC00002 ko00000,ko01000,ko01003,ko01005 Bacteria 2GIT7@201174,4CZ4P@85004,COG0472@1,COG0472@2 NA|NA|NA M Glycosyl transferase family 4 LPKNPDNH_00052 398513.BBNG_01698 5.2e-116 423.7 Bifidobacteriales ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 R10463 RC00745 ko00000,ko01000,ko03009,ko03016 Bacteria 2GK2X@201174,4CYVA@85004,COG0009@1,COG0009@2 NA|NA|NA J Belongs to the SUA5 family LPKNPDNH_00053 398513.BBNG_01697 2.4e-55 221.5 Bifidobacteriales 2.3.1.79 ko:K00661 ko00000,ko01000 Bacteria 2GNUB@201174,4CZ5K@85004,COG0110@1,COG0110@2 NA|NA|NA S Bacterial transferase hexapeptide repeat protein LPKNPDNH_00054 702459.BBPR_1395 3e-184 651.0 Bifidobacteriales prmC 2.1.1.297 ko:K02493 R10806 RC00003,RC03279 ko00000,ko01000,ko03012 Bacteria 2GMH1@201174,4CZB3@85004,COG2890@1,COG2890@2 NA|NA|NA J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif LPKNPDNH_00055 398513.BBNG_01695 1.2e-189 669.1 Bifidobacteriales prfA ko:K02835 ko00000,ko03012 Bacteria 2GJWG@201174,4CYX4@85004,COG0216@1,COG0216@2 NA|NA|NA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA LPKNPDNH_00056 398513.BBNG_01694 3.9e-36 156.8 Bifidobacteriales rpmE GO:0008150,GO:0040007 ko:K02909 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ4I@201174,4D17F@85004,COG0254@1,COG0254@2 NA|NA|NA J Binds the 23S rRNA LPKNPDNH_00058 702459.BBPR_1398 2.1e-196 691.4 Bifidobacteriales Bacteria 2GIRA@201174,4D1HZ@85004,COG4977@1,COG4977@2 NA|NA|NA K helix_turn_helix, arabinose operon control protein LPKNPDNH_00059 398513.BBNG_01692 2.6e-163 581.3 Bifidobacteriales glcU ko:K05340 ko00000,ko02000 2.A.7.5 Bacteria 2IBUA@201174,4CZIZ@85004,COG4975@1,COG4975@2 NA|NA|NA G Sugar transport protein LPKNPDNH_00060 398513.BBNG_01691 1.3e-177 629.0 Bifidobacteriales iolG 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 R01183,R09951 RC00182 ko00000,ko00001,ko01000 Bacteria 2GJCY@201174,4D1RS@85004,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, C-terminal alpha/beta domain LPKNPDNH_00061 398513.BBNG_01690 7.1e-258 896.0 Bifidobacteriales cma 2.1.1.79 ko:K00574 ko00000,ko01000 Bacteria 2GJ94@201174,4D016@85004,COG2230@1,COG2230@2 NA|NA|NA M Mycolic acid cyclopropane synthetase LPKNPDNH_00062 398513.BBNG_01689 1.5e-108 399.1 Bacteria Bacteria 2DPD8@1,331K3@2 NA|NA|NA LPKNPDNH_00063 398513.BBNG_01687 8.3e-170 602.8 Bifidobacteriales yeaD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 4.2.1.9,5.1.3.15 ko:K01687,ko:K01792 ko00010,ko00290,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00010,map00290,map00770,map01100,map01110,map01120,map01130,map01210,map01230 M00019,M00570 R01209,R02739,R04441,R05070 RC00468,RC00563,RC01714 ko00000,ko00001,ko00002,ko01000 Bacteria 2IIUH@201174,4CZWN@85004,COG0676@1,COG0676@2 NA|NA|NA G Aldose 1-epimerase LPKNPDNH_00064 702459.BBPR_1404 1.2e-141 509.6 Bifidobacteriales 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 2HZMP@201174,4D0YE@85004,COG2367@1,COG2367@2 NA|NA|NA V Beta-lactamase enzyme family LPKNPDNH_00065 702459.BBPR_1405 0.0 1092.4 Bifidobacteriales deaD 3.6.4.13 ko:K05592,ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 2GIUR@201174,4CZ4K@85004,COG0513@1,COG0513@2 NA|NA|NA JKL helicase superfamily c-terminal domain LPKNPDNH_00066 398513.BBNG_01684 4.2e-164 583.9 Bifidobacteriales Bacteria 2I8X5@201174,4D011@85004,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family LPKNPDNH_00068 398513.BBNG_01683 1.1e-140 506.1 Bifidobacteriales ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GMGJ@201174,4CZ0B@85004,COG0577@1,COG0577@2 NA|NA|NA V FtsX-like permease family LPKNPDNH_00069 398513.BBNG_01682 3.4e-147 527.7 Bifidobacteriales ko:K07090 ko00000 Bacteria 2GJCC@201174,4CZ65@85004,COG0730@1,COG0730@2 NA|NA|NA S Sulfite exporter TauE/SafE LPKNPDNH_00071 398513.BBNG_01681 1.9e-26 124.4 Bifidobacteriales GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 ko:K07485 ko00000 Bacteria 2H04X@201174,4D1RY@85004,COG3464@1,COG3464@2 NA|NA|NA L Transposase LPKNPDNH_00072 702459.BBPR_1410 1.7e-215 755.0 Bifidobacteriales MA20_36090 Bacteria 2GMT6@201174,4CZ4Q@85004,COG1073@1,COG1073@2 NA|NA|NA S Psort location Cytoplasmic, score 8.87 LPKNPDNH_00073 398513.BBNG_01679 3.4e-252 877.1 Bifidobacteriales metY 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 Bacteria 2I2EB@201174,4CYSA@85004,COG2873@1,COG2873@2 NA|NA|NA H Psort location Cytoplasmic, score 9.98 LPKNPDNH_00074 398513.BBNG_01678 9.3e-36 155.6 Bifidobacteriales 1.1.1.122,1.1.1.65 ko:K00064,ko:K05275 ko00051,ko00053,ko00750,ko01100,ko01110,ko01120,map00051,map00053,map00750,map01100,map01110,map01120 M00114 R01708,R07675,R08926 RC00066,RC00116,RC00161 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMT5@201174,4CZ8K@85004,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family LPKNPDNH_00075 398513.BBNG_01677 6.8e-73 280.0 Bifidobacteriales ko:K18926 M00715 ko00000,ko00002,ko02000 2.A.1.3.30 Bacteria 2GIZX@201174,4D2XT@85004,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator superfamily LPKNPDNH_00076 216816.GS08_08385 4e-10 70.5 Bifidobacteriales Bacteria 2IHK6@201174,4D0T3@85004,COG1846@1,COG1846@2 NA|NA|NA K Winged helix DNA-binding domain LPKNPDNH_00077 398513.BBNG_01675 3.7e-179 634.0 Bifidobacteriales glkA GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJCQ@201174,4CZF6@85004,COG1940@1,COG1940@2 NA|NA|NA G ROK family LPKNPDNH_00078 702459.BBPR_1417 7.8e-299 1032.3 Bifidobacteriales ko:K15738,ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 3.A.1.120.6,3.A.1.121.1,3.A.1.121.3 Bacteria 2GKZC@201174,4CZ9C@85004,COG0488@1,COG0488@2 NA|NA|NA S ATPases associated with a variety of cellular activities LPKNPDNH_00079 702459.BBPR_1418 1.2e-55 222.2 Bifidobacteriales ko:K18552,ko:K18926,ko:K19577 M00715 br01600,ko00000,ko00002,ko01504,ko02000 2.A.1.2.3,2.A.1.2.65,2.A.1.3.30 Bacteria 2H828@201174,4D2HX@85004,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily LPKNPDNH_00080 702459.BBPR_1419 1.1e-158 565.8 Bifidobacteriales Bacteria 2HZCA@201174,4CZQE@85004,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold LPKNPDNH_00081 702459.BBPR_1420 1.1e-110 406.0 Bifidobacteriales ko:K07005 ko00000 Bacteria 2IGUA@201174,4D0SF@85004,COG3467@1,COG3467@2 NA|NA|NA S Pyridoxamine 5'-phosphate oxidase LPKNPDNH_00083 158787.BSCA_0849 1.3e-55 222.6 Bifidobacteriales Bacteria 2GMGZ@201174,4D0BS@85004,COG1434@1,COG1434@2 NA|NA|NA S DUF218 domain LPKNPDNH_00084 158787.BSCA_0868 6.3e-17 94.0 Bifidobacteriales Bacteria 2I9GU@201174,4D0KP@85004,COG3817@1,COG3817@2 NA|NA|NA S Protein of unknown function (DUF979) LPKNPDNH_00085 398513.BBNG_01666 1.7e-114 418.7 Bifidobacteriales pcp GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.19.3 ko:K01304 ko00000,ko01000,ko01002 Bacteria 2GN39@201174,4D03R@85004,COG2039@1,COG2039@2 NA|NA|NA O Removes 5-oxoproline from various penultimate amino acid residues except L-proline LPKNPDNH_00087 398513.BBNG_01665 5.7e-126 456.8 Bifidobacteriales Bacteria 2EINA@1,2ICYX@201174,33CDM@2,4CZUT@85004 NA|NA|NA LPKNPDNH_00088 702459.BBPR_1426 4.7e-48 198.0 Bifidobacteriales Bacteria 2II95@201174,4D0VT@85004,COG3757@1,COG3757@2 NA|NA|NA M domain, Protein LPKNPDNH_00089 78346.BRUM_0591 9.6e-15 86.3 Bifidobacteriales Bacteria 2II95@201174,4D0VT@85004,COG3757@1,COG3757@2 NA|NA|NA M domain, Protein LPKNPDNH_00090 702459.BBPR_1428 2.8e-37 160.6 Bacteria Bacteria 2DR2K@1,339WC@2 NA|NA|NA S Protein of unknown function (DUF3791) LPKNPDNH_00091 702459.BBPR_1429 1.4e-89 335.5 Bifidobacteriales Bacteria 29W75@1,2H7F0@201174,30HSC@2,4D2E1@85004 NA|NA|NA S Protein of unknown function (DUF3990) LPKNPDNH_00092 1280698.AUJS01000115_gene1194 2e-07 61.6 Clostridia Bacteria 1VEKQ@1239,24W5G@186801,2E48D@1,32Z49@2 NA|NA|NA LPKNPDNH_00093 702459.BBPR_1431 2.9e-101 374.4 Bifidobacteriales fic GO:0008150,GO:0050789,GO:0050794,GO:0051302,GO:0065007 ko:K04095 ko00000,ko03036 Bacteria 2IN0D@201174,4D03T@85004,COG2184@1,COG2184@2 NA|NA|NA D Fic/DOC family LPKNPDNH_00095 702459.BBPR_1434 1.2e-97 362.5 Bacteria Bacteria 2C6GH@1,32RH9@2 NA|NA|NA S Domain of unknown function (DUF4825) LPKNPDNH_00096 702459.BBPR_1435 2.5e-43 181.0 Bacteria Bacteria COG2197@1,COG2197@2 NA|NA|NA K response regulator LPKNPDNH_00097 702459.BBPR_1436 2.1e-45 188.0 Actinobacteria Bacteria 2GTBG@201174,COG2197@1,COG2197@2 NA|NA|NA T response regulator LPKNPDNH_00098 398513.BBNG_01661 2.4e-306 1057.4 Bifidobacteriales yjjK GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 Bacteria 2GKBQ@201174,4CYWH@85004,COG0488@1,COG0488@2 NA|NA|NA S ATP-binding cassette protein, ChvD family LPKNPDNH_00099 702459.BBPR_1438 0.0 2152.1 Actinobacteria 3.2.1.52,3.2.1.83 ko:K12373,ko:K20846 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 GH16,GH20 Bacteria 2GK90@201174,COG3525@1,COG3525@2,COG5492@1,COG5492@2 NA|NA|NA G hydrolase family 20, catalytic LPKNPDNH_00100 702459.BBPR_1439 7.1e-172 609.8 Bifidobacteriales tesB ko:K10805 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Bacteria 2GJ1B@201174,4CZRC@85004,COG1946@1,COG1946@2 NA|NA|NA I Thioesterase-like superfamily LPKNPDNH_00101 398513.BBNG_01658 1.3e-77 295.8 Bifidobacteriales Bacteria 2DRQG@1,2HZP6@201174,33CMQ@2,4D14M@85004 NA|NA|NA S Protein of unknown function (DUF3180) LPKNPDNH_00102 398513.BBNG_01657 2.1e-293 1014.2 Bifidobacteriales folK GO:0000287,GO:0003674,GO:0003824,GO:0003848,GO:0005488,GO:0008150,GO:0016740,GO:0016772,GO:0016778,GO:0040007,GO:0043167,GO:0043169,GO:0046872 1.13.11.81,2.5.1.15,2.7.6.3,3.5.4.16,3.5.4.39,4.1.2.25,5.1.99.8 ko:K00796,ko:K00950,ko:K01495,ko:K01633,ko:K13940,ko:K17488 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841,M00842,M00843 R00428,R03066,R03067,R03503,R03504,R04639,R05046,R05048,R10348,R11037,R11073 RC00002,RC00017,RC00121,RC00263,RC00294,RC00323,RC00721,RC00842,RC00943,RC00945,RC01188,RC01479,RC02504,RC03131,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 iECDH1ME8569_1439.ECDH1ME8569_0136,iEcDH1_1363.EcDH1_3460,iJN746.PP_4698,iLJ478.TM0041,iSBO_1134.SBO_0131 Bacteria 2H3G6@201174,4D0EJ@85004,COG0801@1,COG0801@2,COG1539@1,COG1539@2 NA|NA|NA H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin LPKNPDNH_00103 702459.BBPR_1443 2.3e-164 584.7 Bifidobacteriales folP 1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8 ko:K00796,ko:K00950,ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841 R03066,R03067,R03503,R03504,R11037,R11073 RC00002,RC00017,RC00121,RC00721,RC00842,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJDQ@201174,4CZWW@85004,COG0294@1,COG0294@2 NA|NA|NA H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives LPKNPDNH_00104 398513.BBNG_01655 4.5e-100 370.5 Bifidobacteriales folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R03503,R04639,R05046,R05048 RC00002,RC00017,RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 iIT341.HP0928 Bacteria 2GP2P@201174,4CZ5S@85004,COG0302@1,COG0302@2 NA|NA|NA H GTP cyclohydrolase LPKNPDNH_00105 398513.BBNG_01654 0.0 1352.0 Bifidobacteriales ftsH GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 ko:K03798 M00742 ko00000,ko00002,ko01000,ko01002,ko03110 Bacteria 2GJ4Q@201174,4CZ6U@85004,COG0465@1,COG0465@2 NA|NA|NA O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins LPKNPDNH_00106 398513.BBNG_01653 9.4e-98 362.8 Bifidobacteriales hpt 2.4.2.8,6.3.4.19 ko:K00760,ko:K04075,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 Bacteria 2GMDZ@201174,4CZNJ@85004,COG0634@1,COG0634@2 NA|NA|NA F Belongs to the purine pyrimidine phosphoribosyltransferase family LPKNPDNH_00107 398513.BBNG_01652 1.1e-211 742.3 Bifidobacteriales tilS 2.4.2.8,6.3.4.19 ko:K00760,ko:K04075,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 Bacteria 2GJR4@201174,4CYSY@85004,COG0037@1,COG0037@2 NA|NA|NA J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine LPKNPDNH_00108 702459.BBPR_1448 4.5e-261 906.7 Bifidobacteriales dacB 3.4.16.4 ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 2GJPH@201174,4CYXQ@85004,COG2027@1,COG2027@2 NA|NA|NA M D-Ala-D-Ala carboxypeptidase 3 (S13) family LPKNPDNH_00109 702459.BBPR_1449 5e-309 1066.2 Bifidobacteriales ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2BWH2@1,2GMNW@201174,2Z89R@2,4CZP3@85004 NA|NA|NA LPKNPDNH_00110 398513.BBNG_01649 1.7e-168 598.6 Bifidobacteriales natA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GIY8@201174,4CZ0Q@85004,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities LPKNPDNH_00111 398513.BBNG_01648 1.3e-232 812.0 Bifidobacteriales epsG ko:K00786 ko00000,ko01000 Bacteria 2HZ9V@201174,4CZ5J@85004,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family 21 LPKNPDNH_00112 398513.BBNG_01647 4.3e-273 946.8 Bifidobacteriales Bacteria 2GN4Y@201174,4CZD1@85004,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter LPKNPDNH_00113 398513.BBNG_01646 4.3e-177 627.1 Bifidobacteriales 3.4.14.13 ko:K20742 ko00000,ko01000,ko01002 Bacteria 2GNPU@201174,4CZ7E@85004,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase like family 2 LPKNPDNH_00114 702459.BBPR_1454 8.1e-205 719.5 Bifidobacteriales fucO GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006004,GO:0006066,GO:0008150,GO:0008152,GO:0008198,GO:0008912,GO:0009056,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019299,GO:0019301,GO:0019317,GO:0019318,GO:0019320,GO:0019751,GO:0034311,GO:0034313,GO:0042354,GO:0042355,GO:0042844,GO:0042846,GO:0043167,GO:0043169,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0046365,GO:0046872,GO:0046914,GO:0051143,GO:0055114,GO:0071704,GO:1901575,GO:1901615,GO:1901616 1.1.1.1,1.1.1.77,1.1.99.37,1.2.98.1 ko:K00048,ko:K13954,ko:K17067 ko00010,ko00071,ko00350,ko00625,ko00626,ko00630,ko00640,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00071,map00350,map00625,map00626,map00630,map00640,map00680,map01100,map01110,map01120,map01130,map01200,map01220 R00614,R00623,R00754,R01781,R02257,R04880,R05233,R05234,R06917,R06927 RC00034,RC00050,RC00087,RC00088,RC00099,RC00116,RC00188,RC00649 ko00000,ko00001,ko01000 iAF1260.b2799,iECDH1ME8569_1439.ECDH1ME8569_2709,iECSE_1348.ECSE_3059,iECW_1372.ECW_m3009,iEKO11_1354.EKO11_0969,iEcDH1_1363.EcDH1_0889,iEcE24377_1341.EcE24377A_3104,iEcHS_1320.EcHS_A2943,iJO1366.b2799,iJR904.b2799,iUMNK88_1353.UMNK88_3484,iWFL_1372.ECW_m3009,iY75_1357.Y75_RS14565 Bacteria 2I2FD@201174,4CZ71@85004,COG1454@1,COG1454@2 NA|NA|NA C Iron-containing alcohol dehydrogenase LPKNPDNH_00117 702459.BBPR_1455 2.6e-68 265.4 Bifidobacteriales Bacteria 2EGCD@1,2I2HS@201174,33A46@2,4D1EH@85004 NA|NA|NA S Domain of unknown function (DUF4190) LPKNPDNH_00118 398513.BBNG_01643 1.2e-199 702.2 Bifidobacteriales galE 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMCW@201174,4CZDB@85004,COG1087@1,COG1087@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family LPKNPDNH_00119 398513.BBNG_01642 1.6e-154 552.0 Bifidobacteriales trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.297,2.1.1.33,2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02493,ko:K02527,ko:K03439 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763,R10806 RC00003,RC00009,RC00077,RC00247,RC03279 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko03012,ko03016 GT30 Bacteria 2GJ8R@201174,4CZKF@85004,COG0220@1,COG0220@2 NA|NA|NA J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA LPKNPDNH_00121 398513.BBNG_01639 8.6e-268 929.1 Bifidobacteriales lacS ko:K03292,ko:K11104,ko:K16209 ko00000,ko02000 2.A.2,2.A.2.1,2.A.2.2 Bacteria 2HD4Y@201174,4CZRA@85004,COG2211@1,COG2211@2 NA|NA|NA G Psort location CytoplasmicMembrane, score 10.00 LPKNPDNH_00122 702459.BBPR_1460 0.0 2196.4 Bifidobacteriales lacL 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 Bacteria 2GMAT@201174,4CYYS@85004,COG3250@1,COG3250@2 NA|NA|NA G Psort location Cytoplasmic, score 8.87 LPKNPDNH_00123 398513.BBNG_01637 1.7e-90 338.6 Bifidobacteriales nagA 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 R02059 RC00166,RC00300 ko00000,ko00001,ko01000 Bacteria 2GK1E@201174,4CZKB@85004,COG1820@1,COG1820@2 NA|NA|NA G Amidohydrolase family LPKNPDNH_00124 398513.BBNG_01636 3e-183 647.9 Bifidobacteriales lacR ko:K02529 ko00000,ko03000 Bacteria 2H5ZG@201174,4CZ8A@85004,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator, LacI family LPKNPDNH_00125 702459.BBPR_1463 5.2e-229 800.0 Bifidobacteriales Bacteria 2GJMV@201174,4D0NT@85004,COG0642@1,COG2205@2 NA|NA|NA T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain LPKNPDNH_00126 398513.BBNG_01634 3.9e-119 434.1 Bifidobacteriales Bacteria 2GKYV@201174,4D0DR@85004,COG0745@1,COG0745@2 NA|NA|NA K Transcriptional regulatory protein, C terminal LPKNPDNH_00127 398513.BBNG_01633 4.8e-101 374.0 Bifidobacteriales Bacteria 2F769@1,2IEMY@201174,31WPC@2,4D0CX@85004 NA|NA|NA LPKNPDNH_00128 702459.BBPR_1465 1.5e-178 632.1 Bifidobacteriales Bacteria 2IA8Z@201174,4D0JZ@85004,COG3023@1,COG3023@2 NA|NA|NA V N-Acetylmuramoyl-L-alanine amidase LPKNPDNH_00129 398513.BBNG_01631 1.6e-108 398.7 Bifidobacteriales ytrE ko:K02003,ko:K10038 ko02010,map02010 M00227,M00258 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.3.2 Bacteria 2ICH8@201174,4D0ET@85004,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter LPKNPDNH_00130 702459.BBPR_1467 6.6e-172 610.1 Bifidobacteriales Bacteria 2C746@1,2HM24@201174,32RIC@2,4D0FF@85004 NA|NA|NA LPKNPDNH_00132 702459.BBPR_1469 4.7e-220 770.4 Bifidobacteriales vex3 ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2I99G@201174,4D0H6@85004,COG0577@1,COG0577@2 NA|NA|NA V ABC transporter permease LPKNPDNH_00133 702459.BBPR_1470 3.2e-212 744.2 Bifidobacteriales vex1 ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IA7B@201174,4CZJM@85004,COG0577@1,COG0577@2 NA|NA|NA V Efflux ABC transporter, permease protein LPKNPDNH_00134 702459.BBPR_1471 1.3e-111 409.1 Bifidobacteriales vex2 ko:K02003,ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2I7UV@201174,4CZ1C@85004,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein LPKNPDNH_00135 398513.BBNG_01625 1.7e-35 154.8 Bifidobacteriales azlD Bacteria 2HZNQ@201174,4D12M@85004,COG1687@1,COG1687@2 NA|NA|NA E Branched-chain amino acid transport protein (AzlD) LPKNPDNH_00136 702459.BBPR_1473 2.2e-196 691.4 Bifidobacteriales afr_2 Bacteria 2GKW0@201174,4CYXG@85004,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold LPKNPDNH_00137 398513.BBNG_01622 6.2e-96 356.7 Bifidobacteriales ptpA GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 ko:K01104,ko:K20945 ko05111,map05111 ko00000,ko00001,ko01000 Bacteria 2IM0Q@201174,4CZWM@85004,COG0394@1,COG0394@2 NA|NA|NA T low molecular weight LPKNPDNH_00138 398513.BBNG_01621 4.6e-128 463.8 Bifidobacteriales folA GO:0000166,GO:0003674,GO:0003824,GO:0004146,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070401,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2763c Bacteria 2IM1S@201174,4CZM1@85004,COG0262@1,COG0262@2 NA|NA|NA H dihydrofolate reductase LPKNPDNH_00139 702459.BBPR_1477 1.9e-174 618.2 Bifidobacteriales thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKY0@201174,4CZQ3@85004,COG0207@1,COG0207@2 NA|NA|NA F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis LPKNPDNH_00140 398513.BBNG_01619 8.5e-72 276.2 Bifidobacteriales attW GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2IIK7@201174,4D0PB@85004,COG1765@1,COG1765@2 NA|NA|NA O OsmC-like protein LPKNPDNH_00141 702459.BBPR_1479 7.8e-191 672.9 Bifidobacteriales Bacteria 2GMFE@201174,4CZ6V@85004,COG0589@1,COG0589@2 NA|NA|NA T Universal stress protein family LPKNPDNH_00142 702459.BBPR_1480 1.7e-105 389.0 Bifidobacteriales ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 2GIWB@201174,4D2RF@85004,COG0791@1,COG0791@2 NA|NA|NA M NlpC/P60 family LPKNPDNH_00143 702459.BBPR_1481 9.1e-176 622.9 Bifidobacteriales usp 3.5.1.28 ko:K21471,ko:K22409 ko00000,ko01000,ko01002,ko01011 CBM50 Bacteria 2GP2A@201174,4CYXV@85004,COG3942@1,COG3942@2 NA|NA|NA S CHAP domain LPKNPDNH_00144 398513.BBNG_01614 8.5e-215 752.7 Bifidobacteriales serC GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GKYK@201174,4CZ94@85004,COG1932@1,COG1932@2 NA|NA|NA E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine LPKNPDNH_00145 398513.BBNG_01613 2.6e-39 167.5 Bifidobacteriales Bacteria 2EG1H@1,2IQTR@201174,339TH@2,4D16E@85004 NA|NA|NA LPKNPDNH_00146 702459.BBPR_1484 2.3e-216 758.1 Bifidobacteriales Bacteria 2GJY7@201174,4CZIM@85004,COG5002@1,COG5002@2 NA|NA|NA T ATPase histidine kinase DNA gyrase B HSP90 domain protein LPKNPDNH_00147 398513.BBNG_01611 1.7e-117 428.7 Bifidobacteriales phoU ko:K02039 ko00000 Bacteria 2GKAD@201174,4CZ9B@85004,COG0704@1,COG0704@2 NA|NA|NA P Plays a role in the regulation of phosphate uptake LPKNPDNH_00148 398513.BBNG_01609 4.9e-139 500.4 Bifidobacteriales gpmA GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 2GK8F@201174,4CZMF@85004,COG0588@1,COG0588@2 NA|NA|NA G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate LPKNPDNH_00149 398513.BBNG_01608 4.3e-175 620.5 Bifidobacteriales menA GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046428,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 iECH74115_1262.ECH74115_5387,iG2583_1286.G2583_4737 Bacteria 2GJBS@201174,4CZHQ@85004,COG1575@1,COG1575@2 NA|NA|NA H Belongs to the MenA family. Type 1 subfamily LPKNPDNH_00150 398513.BBNG_01607 0.0 1129.0 Bifidobacteriales lysS GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF1260.b4129,iECDH1ME8569_1439.ECDH1ME8569_3989,iECW_1372.ECW_m4490,iEcDH1_1363.EcDH1_3862,iJN678.lysS,iJO1366.b4129,iWFL_1372.ECW_m4490 Bacteria 2GKE0@201174,4CZHM@85004,COG1190@1,COG1190@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family LPKNPDNH_00152 398513.BBNG_01606 1.2e-216 758.8 Bifidobacteriales araJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K08156,ko:K19577 ko00000,ko02000 2.A.1.2.14,2.A.1.2.65 Bacteria 2GK8C@201174,4CZ46@85004,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily LPKNPDNH_00153 702459.BBPR_1491 0.0 1185.6 Bifidobacteriales Bacteria 2I7P1@201174,4CZTS@85004,COG0457@1,COG0457@2 NA|NA|NA S Domain of unknown function (DUF4037) LPKNPDNH_00154 398513.BBNG_01604 4.3e-112 410.6 Bifidobacteriales Bacteria 2DM2Z@1,2GKMX@201174,31HGC@2,4CZJ9@85004 NA|NA|NA S Protein of unknown function (DUF4125) LPKNPDNH_00155 702459.BBPR_1493 2.1e-129 468.8 Bifidobacteriales Bacteria 2BIES@1,2GSGC@201174,32CM6@2,4D1KF@85004 NA|NA|NA LPKNPDNH_00156 398513.BBNG_01602 1.9e-290 1004.6 Bifidobacteriales pspC Bacteria 2GIVS@201174,4CZZT@85004,COG1983@1,COG1983@2 NA|NA|NA KT PspC domain LPKNPDNH_00157 702459.BBPR_1495 8.9e-273 945.7 Bifidobacteriales tcsS3 Bacteria 2GJ4J@201174,4CZ2U@85004,COG1983@1,COG1983@2,COG4585@1,COG4585@2 NA|NA|NA KT PspC domain LPKNPDNH_00158 398513.BBNG_01600 9.2e-126 456.4 Bifidobacteriales degU ko:K07684 ko02020,map02020 M00471 ko00000,ko00001,ko00002,ko02022 Bacteria 2GIVA@201174,4CZW8@85004,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon LPKNPDNH_00159 398513.BBNG_01599 5.3e-278 963.0 Bifidobacteriales gnd GO:0003674,GO:0003824,GO:0004616,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019520,GO:0019521,GO:0019637,GO:0019682,GO:0019693,GO:0019752,GO:0032787,GO:0034641,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046176,GO:0046177,GO:0046395,GO:0046483,GO:0046496,GO:0046983,GO:0051156,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072329,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 iECS88_1305.ECS88_2128,iECW_1372.ECW_m2189,iEKO11_1354.EKO11_1765,iPC815.YPO1541,iWFL_1372.ECW_m2189 Bacteria 2GJ2J@201174,4CZFG@85004,COG0362@1,COG0362@2 NA|NA|NA H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH LPKNPDNH_00161 398513.BBNG_01598 6e-143 513.5 Bifidobacteriales pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 ko:K01057,ko:K02003 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008,M00258 R02035 RC00537 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1 Bacteria 2GMQ2@201174,4CZRG@85004,COG0363@1,COG0363@2 NA|NA|NA G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase LPKNPDNH_00162 702459.BBPR_1499 7.2e-186 656.4 Bifidobacteriales opcA Bacteria 2GJ1H@201174,4CZI4@85004,COG3429@1,COG3429@2 NA|NA|NA G Glucose-6-phosphate dehydrogenase subunit LPKNPDNH_00163 702459.BBPR_1500 0.0 1082.8 Bifidobacteriales zwf 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 iIT341.HP1101 Bacteria 2GISI@201174,4CYQM@85004,COG0364@1,COG0364@2 NA|NA|NA G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone LPKNPDNH_00164 702459.BBPR_1501 1.2e-94 352.4 Bifidobacteriales Bacteria 2DNNA@1,2ISEY@201174,32Y8E@2,4D1A0@85004 NA|NA|NA LPKNPDNH_00166 702459.BBPR_1503 0.0 3496.8 Actinobacteria nagLU 3.1.4.53,3.2.1.21,3.2.1.50 ko:K01205,ko:K03651,ko:K05349 ko00230,ko00460,ko00500,ko00531,ko00940,ko01100,ko01110,ko02025,ko04142,map00230,map00460,map00500,map00531,map00940,map01100,map01110,map02025,map04142 M00078 R00026,R00191,R02558,R02887,R02985,R03527,R04949,R04998,R07816,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00296,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko00002,ko01000,ko04147 GH3 Bacteria 2GNPW@201174,COG1409@1,COG1409@2,COG1572@1,COG1572@2,COG3669@1,COG3669@2 NA|NA|NA G Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain LPKNPDNH_00168 398513.BBNG_01592 4.7e-238 830.1 Bifidobacteriales serS GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GIWP@201174,4CZ40@85004,COG0172@1,COG0172@2 NA|NA|NA J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) LPKNPDNH_00169 702459.BBPR_1505 0.0 2889.0 Bifidobacteriales nucH 3.1.3.5 ko:K01081,ko:K07004 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 Bacteria 2GKC3@201174,4D03Y@85004,COG0737@1,COG0737@2,COG2374@1,COG2374@2 NA|NA|NA F 5'-nucleotidase, C-terminal domain LPKNPDNH_00170 398513.BBNG_01590 5.1e-212 743.4 Bifidobacteriales Bacteria 2GJ3K@201174,4CYTC@85004,COG1597@1,COG1597@2 NA|NA|NA I Diacylglycerol kinase catalytic domain LPKNPDNH_00171 398513.BBNG_01589 1.3e-151 542.3 Bifidobacteriales arbG ko:K02538,ko:K03488 ko00000,ko03000 Bacteria 2I8K8@201174,4D08T@85004,COG3711@1,COG3711@2 NA|NA|NA K CAT RNA binding domain LPKNPDNH_00172 398513.BBNG_01588 0.0 1130.9 Bifidobacteriales crr GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006109,GO:0006793,GO:0006796,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009892,GO:0009898,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019222,GO:0019897,GO:0019898,GO:0031234,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045912,GO:0048519,GO:0050789,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071944,GO:0080090,GO:0098552,GO:0098562 ko:K02755,ko:K02756,ko:K02757,ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00271,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 e_coli_core.b2417,iAF1260.b2417,iAPECO1_1312.APECO1_4128,iB21_1397.B21_02278,iBWG_1329.BWG_2179,iE2348C_1286.E2348C_2603,iEC042_1314.EC042_2626,iEC55989_1330.EC55989_2707,iECABU_c1320.ECABU_c27380,iECBD_1354.ECBD_1264,iECB_1328.ECB_02317,iECDH10B_1368.ECDH10B_2582,iECDH1ME8569_1439.ECDH1ME8569_2351,iECD_1391.ECD_02317,iECED1_1282.ECED1_2861,iECH74115_1262.ECH74115_3648,iECIAI1_1343.ECIAI1_2475,iECIAI39_1322.ECIAI39_2563,iECNA114_1301.ECNA114_2494,iECO103_1326.ECO103_2936,iECO111_1330.ECO111_3147,iECO26_1355.ECO26_3470,iECOK1_1307.ECOK1_2734,iECS88_1305.ECS88_2607,iECSE_1348.ECSE_2708,iECSF_1327.ECSF_2281,iECSP_1301.ECSP_3365,iECUMN_1333.ECUMN_2739,iECW_1372.ECW_m2646,iEKO11_1354.EKO11_1311,iETEC_1333.ETEC_2530,iEcDH1_1363.EcDH1_1244,iEcE24377_1341.EcE24377A_2704,iEcHS_1320.EcHS_A2552,iEcSMS35_1347.EcSMS35_2572,iEcolC_1368.EcolC_1261,iG2583_1286.G2583_2949,iJO1366.b2417,iJR904.b2417,iLF82_1304.LF82_0357,iNRG857_1313.NRG857_12120,iSFV_1184.SFV_2469,iSF_1195.SF2472,iSFxv_1172.SFxv_2721,iSSON_1240.SSON_2506,iS_1188.S2618,iUMN146_1321.UM146_04535,iUMNK88_1353.UMNK88_3019,iUTI89_1310.UTI89_C2751,iWFL_1372.ECW_m2646,iY75_1357.Y75_RS12665,ic_1306.c2952 Bacteria 2GK6B@201174,4CZR7@85004,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G pts system, glucose-specific IIABC component LPKNPDNH_00173 398513.BBNG_01586 4.4e-42 177.9 Bifidobacteriales ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2H2BH@201174,4D2YF@85004,COG2304@1,COG2304@2 NA|NA|NA M Spy0128-like isopeptide containing domain LPKNPDNH_00174 398513.BBNG_01586 2.7e-43 181.0 Bifidobacteriales ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2H2BH@201174,4D2YF@85004,COG2304@1,COG2304@2 NA|NA|NA M Spy0128-like isopeptide containing domain LPKNPDNH_00176 398513.BBNG_01585 0.0 1145.6 Bifidobacteriales pgm GO:0000271,GO:0003674,GO:0003824,GO:0004614,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005996,GO:0006006,GO:0006012,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0016868,GO:0019318,GO:0019320,GO:0019388,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0055114,GO:0071704,GO:1901575,GO:1901576 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1376,iECED1_1282.ECED1_0670,iECNA114_1301.ECNA114_0627,iECOK1_1307.ECOK1_0699,iECP_1309.ECP_0709,iECS88_1305.ECS88_0725,iJN678.pgm,iLF82_1304.LF82_1632,iNRG857_1313.NRG857_03110,iUMN146_1321.UM146_14115,iYL1228.KPN_00711 Bacteria 2H1PI@201174,4CZ7X@85004,COG0033@1,COG0033@2 NA|NA|NA G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II LPKNPDNH_00177 702459.BBPR_1513 4.4e-261 906.7 Bifidobacteriales merA GO:0000302,GO:0000305,GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0019725,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901530,GO:1901700,GO:1990748 1.16.1.1,1.8.1.7 ko:K00383,ko:K00520,ko:K21739 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 Bacteria 2GJJK@201174,4CZZF@85004,COG1249@1,COG1249@2 NA|NA|NA C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family LPKNPDNH_00178 702459.BBPR_1514 0.0 3593.1 Actinobacteria nagH 3.2.1.35,3.2.1.52 ko:K01197,ko:K02022,ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00076,M00077,M00079 R00022,R06004,R07824,R07825,R10905,R11316 RC00049 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042,ko03110 GH20 Bacteria 2GM4H@201174,COG0845@1,COG0845@2,COG3525@1,COG3525@2 NA|NA|NA G beta-N-acetylglucosaminidase LPKNPDNH_00179 702459.BBPR_1515 3.8e-204 717.2 Bifidobacteriales rnhA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 2GK53@201174,4CZGC@85004,COG0328@1,COG0328@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids LPKNPDNH_00180 398513.BBNG_01581 5.4e-127 460.3 Bifidobacteriales rpiA GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,5.3.1.6 ko:K00851,ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056,R01737 RC00002,RC00017,RC00434 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMHW@201174,4CZDH@85004,COG0120@1,COG0120@2 NA|NA|NA G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate LPKNPDNH_00182 702459.BBPR_1517 1.2e-106 392.5 Bifidobacteriales Bacteria 2EHBK@1,2ICD4@201174,33B3F@2,4CZY5@85004 NA|NA|NA LPKNPDNH_00183 398513.BBNG_01579 6.1e-255 886.3 Bifidobacteriales radA GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 ko:K04485 ko00000,ko03400 Bacteria 2GMQ0@201174,4CZE1@85004,COG1066@1,COG1066@2 NA|NA|NA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function LPKNPDNH_00184 702459.BBPR_1519 6.9e-234 816.2 Bifidobacteriales ribF GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKQF@201174,4CYXT@85004,COG0196@1,COG0196@2 NA|NA|NA H riboflavin kinase LPKNPDNH_00185 702459.BBPR_1520 1.6e-238 831.6 Bifidobacteriales truB GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177 ko00000,ko01000,ko03016 Bacteria 2GJZK@201174,4CZED@85004,COG0130@1,COG0130@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs LPKNPDNH_00186 398513.BBNG_01576 4.7e-84 317.4 Bifidobacteriales rbfA ko:K02834 ko00000,ko03009 Bacteria 2IKXP@201174,4CZZZ@85004,COG0858@1,COG0858@2 NA|NA|NA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA LPKNPDNH_00187 702459.BBPR_1522 0.0 1541.6 Bifidobacteriales infB ko:K02519 ko00000,ko03012,ko03029 Bacteria 2GKPH@201174,4CZ4B@85004,COG0532@1,COG0532@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex LPKNPDNH_00188 398513.BBNG_01574 2.8e-188 664.5 Bifidobacteriales nusA ko:K02600 ko00000,ko03009,ko03021 Bacteria 2GJDJ@201174,4CYTW@85004,COG0195@1,COG0195@2 NA|NA|NA K Participates in both transcription termination and antitermination LPKNPDNH_00189 702459.BBPR_1524 1.6e-161 575.5 Bifidobacteriales Bacteria 2B54U@1,2HXKT@201174,31XYD@2,4D0IH@85004 NA|NA|NA LPKNPDNH_00190 702459.BBPR_1525 1.1e-145 522.7 Bifidobacteriales Bacteria 2IEJD@201174,4CZ5C@85004,COG3677@1,COG3677@2 NA|NA|NA L Transposase and inactivated derivatives LPKNPDNH_00192 398513.BBNG_01571 1.3e-153 548.9 Bifidobacteriales Bacteria 2GN5D@201174,4CZBJ@85004,COG1305@1,COG1305@2 NA|NA|NA E Transglutaminase/protease-like homologues LPKNPDNH_00193 702459.BBPR_1527 0.0 1474.1 Bifidobacteriales gcs2 Bacteria 2GN0J@201174,4D061@85004,COG2307@1,COG2307@2,COG2308@1,COG2308@2 NA|NA|NA S A circularly permuted ATPgrasp LPKNPDNH_00194 702459.BBPR_1528 3.2e-172 610.9 Bifidobacteriales truA GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.12 ko:K06173 ko00000,ko01000,ko03016 Bacteria 2GJ6C@201174,4CZ8H@85004,COG0101@1,COG0101@2 NA|NA|NA J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs LPKNPDNH_00195 702459.BBPR_1529 0.0 3007.6 Actinobacteria 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 GH20 Bacteria 2GK90@201174,COG0683@1,COG0683@2,COG3525@1,COG3525@2,COG5498@1,COG5498@2 NA|NA|NA G hydrolase family 20, catalytic LPKNPDNH_00196 702459.BBPR_1530 8.1e-64 250.0 Bifidobacteriales rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 ko:K02879 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHV2@201174,4D0PZ@85004,COG0203@1,COG0203@2 NA|NA|NA J Ribosomal protein L17 LPKNPDNH_00197 398513.BBNG_01566 8.9e-184 649.4 Bifidobacteriales rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2GJJ5@201174,4CZEN@85004,COG0202@1,COG0202@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates LPKNPDNH_00198 398513.BBNG_01565 1.1e-65 255.8 Bifidobacteriales rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02948 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IFFC@201174,4D0PJ@85004,COG0100@1,COG0100@2 NA|NA|NA J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome LPKNPDNH_00199 1435051.BMOU_1730 3.3e-62 244.2 Bifidobacteriales rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02952 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHPN@201174,4D0PQ@85004,COG0099@1,COG0099@2 NA|NA|NA J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits LPKNPDNH_00200 1437605.BACT_0253 6.5e-14 82.0 Bifidobacteriales rpmJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02919 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GWMH@201174,4D1NT@85004,COG0257@1,COG0257@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL36 family LPKNPDNH_00201 1435051.BMOU_1728 1.6e-32 144.8 Bifidobacteriales infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009986,GO:0016020,GO:0030246,GO:0030247,GO:0030312,GO:0040007,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071944,GO:2001065 ko:K02518 ko00000,ko03012 Bacteria 2IQ4B@201174,4D16H@85004,COG0361@1,COG0361@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex LPKNPDNH_00202 702459.BBPR_1536 3.8e-99 367.5 Bifidobacteriales adk 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GJ7T@201174,4CZ7Z@85004,COG0563@1,COG0563@2 NA|NA|NA F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism LPKNPDNH_00203 702459.BBPR_1537 4.7e-249 866.7 Bifidobacteriales secY GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5 Bacteria 2GJ26@201174,4CYWU@85004,COG0201@1,COG0201@2 NA|NA|NA U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently LPKNPDNH_00204 398513.BBNG_01559 2.7e-63 248.1 Bifidobacteriales rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02876 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2II6M@201174,4D0R9@85004,COG0200@1,COG0200@2 NA|NA|NA J binds to the 23S rRNA LPKNPDNH_00205 398513.BBNG_01558 1e-24 118.6 Bifidobacteriales rpmD GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02907 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GQV0@201174,4D1EZ@85004,COG1841@1,COG1841@2 NA|NA|NA J Ribosomal protein L30p/L7e LPKNPDNH_00206 702459.BBPR_1540 1.5e-100 372.5 Bifidobacteriales rpsE GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02988 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GJW8@201174,4CZCD@85004,COG0098@1,COG0098@2 NA|NA|NA J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body LPKNPDNH_00207 398513.BBNG_01556 1.1e-57 229.2 Bifidobacteriales rplR GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02881 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IKTX@201174,4D0WE@85004,COG0256@1,COG0256@2 NA|NA|NA J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance LPKNPDNH_00208 398513.BBNG_01555 2.1e-94 351.7 Bifidobacteriales rplF GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02933 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GK35@201174,4CYQV@85004,COG0097@1,COG0097@2 NA|NA|NA J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center LPKNPDNH_00209 398513.BBNG_01554 4.2e-68 263.8 Bifidobacteriales rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02994 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHQZ@201174,4D0P6@85004,COG0096@1,COG0096@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit LPKNPDNH_00210 1437609.BCAL_1317 9.2e-18 95.5 Bifidobacteriales rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02954 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ8R@201174,4D177@85004,COG0199@1,COG0199@2 NA|NA|NA J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site LPKNPDNH_00211 398513.BBNG_01552 2.2e-102 378.3 Bifidobacteriales rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02931 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GJW7@201174,4CZCA@85004,COG0094@1,COG0094@2 NA|NA|NA J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits LPKNPDNH_00212 398513.BBNG_01551 3.5e-52 210.7 Bifidobacteriales rplX GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02895 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IKP2@201174,4D10I@85004,COG0198@1,COG0198@2 NA|NA|NA J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit LPKNPDNH_00213 398513.BBNG_01550 6.6e-60 236.5 Bifidobacteriales rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02874 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHNX@201174,4D0VI@85004,COG0093@1,COG0093@2 NA|NA|NA J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome LPKNPDNH_00214 398513.BBNG_01549 2.2e-41 174.5 Bifidobacteriales rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02961 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ68@201174,4D10N@85004,COG0186@1,COG0186@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA LPKNPDNH_00215 398513.BBNG_01548 5e-38 163.3 Bifidobacteriales rpmC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02904 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ6V@201174,4D181@85004,COG0255@1,COG0255@2 NA|NA|NA J Belongs to the universal ribosomal protein uL29 family LPKNPDNH_00216 398513.BBNG_01547 5.8e-76 290.0 Bifidobacteriales rplP GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02878 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IFEI@201174,4D0Q8@85004,COG0197@1,COG0197@2 NA|NA|NA J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs LPKNPDNH_00217 398513.BBNG_01546 7.5e-96 357.1 Bifidobacteriales rpsC GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02982 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GKF1@201174,4CYQN@85004,COG0092@1,COG0092@2 NA|NA|NA J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation LPKNPDNH_00218 398513.BBNG_01545 4.3e-56 223.8 Bifidobacteriales rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02890 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IM3J@201174,4D0UZ@85004,COG0091@1,COG0091@2 NA|NA|NA J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome LPKNPDNH_00219 1437608.BBIA_2303 3.7e-47 193.7 Bifidobacteriales rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02965 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IKMS@201174,4D105@85004,COG0185@1,COG0185@2 NA|NA|NA J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA LPKNPDNH_00220 398513.BBNG_01543 4.2e-155 553.9 Bifidobacteriales rplB GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02886 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GK7R@201174,4CZ5U@85004,COG0090@1,COG0090@2 NA|NA|NA J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity LPKNPDNH_00221 398513.BBNG_01542 2.6e-46 191.0 Bifidobacteriales rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02892 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ7V@201174,4D11N@85004,COG0089@1,COG0089@2 NA|NA|NA J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome LPKNPDNH_00222 702459.BBPR_1556 3.9e-119 434.1 Bifidobacteriales rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02926 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GJYJ@201174,4CZSA@85004,COG0088@1,COG0088@2 NA|NA|NA J Forms part of the polypeptide exit tunnel LPKNPDNH_00223 398513.BBNG_01540 4.2e-118 430.6 Bifidobacteriales rplC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 ko:K02906 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GJXT@201174,4CYQD@85004,COG0087@1,COG0087@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit LPKNPDNH_00224 1435051.BMOU_1705 5.2e-50 203.4 Bifidobacteriales rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02946 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHRA@201174,4D0UT@85004,COG0051@1,COG0051@2 NA|NA|NA J Involved in the binding of tRNA to the ribosomes LPKNPDNH_00225 398513.BBNG_01538 1.4e-58 232.6 Bifidobacteriales ywiC Bacteria 28NT3@1,2IIC3@201174,2ZBRV@2,4D0MQ@85004 NA|NA|NA S YwiC-like protein LPKNPDNH_00226 398513.BBNG_01538 9.7e-90 336.3 Bifidobacteriales ywiC Bacteria 28NT3@1,2IIC3@201174,2ZBRV@2,4D0MQ@85004 NA|NA|NA S YwiC-like protein LPKNPDNH_00227 702459.BBPR_1562 6.2e-157 560.1 Bifidobacteriales budA GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0047605 4.1.1.5 ko:K01575 ko00650,ko00660,map00650,map00660 R02948 RC00812 ko00000,ko00001,ko01000 Bacteria 2IBRH@201174,4D0BN@85004,COG3527@1,COG3527@2 NA|NA|NA H Alpha-acetolactate decarboxylase LPKNPDNH_00228 398513.BBNG_01536 0.0 1804.6 Bifidobacteriales adhE 1.1.1.1,1.2.1.10 ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 iSB619.SA_RS00885 Bacteria 2GJI2@201174,4CZ8F@85004,COG1012@1,COG1012@2,COG1454@1,COG1454@2 NA|NA|NA C belongs to the iron- containing alcohol dehydrogenase family LPKNPDNH_00229 398513.BBNG_01535 6.9e-231 806.2 Bifidobacteriales 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2I7R8@201174,4CZZ7@85004,COG1940@1,COG1940@2 NA|NA|NA GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565 LPKNPDNH_00230 398513.BBNG_01534 0.0 1760.0 Bifidobacteriales glgX 3.2.1.196,3.2.1.68 ko:K01214,ko:K02438 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02111,R09995,R11261 ko00000,ko00001,ko00002,ko01000 CBM48,GH13 Bacteria 2GJ00@201174,4CYZ1@85004,COG1523@1,COG1523@2 NA|NA|NA G Belongs to the glycosyl hydrolase 13 family LPKNPDNH_00231 398513.BBNG_01533 8.8e-68 263.1 Bifidobacteriales rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02996 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GNDY@201174,4CZ9Y@85004,COG0103@1,COG0103@2 NA|NA|NA J Belongs to the universal ribosomal protein uS9 family LPKNPDNH_00232 398513.BBNG_01532 3.5e-79 300.8 Bifidobacteriales rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02871 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IFG1@201174,4D0PV@85004,COG0102@1,COG0102@2 NA|NA|NA J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly LPKNPDNH_00233 702459.BBPR_1571 0.0 1485.3 Bifidobacteriales malQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.4.1.18,2.4.1.25,3.2.1.196,5.4.99.15 ko:K00700,ko:K00705,ko:K02438,ko:K06044 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R01824,R02110,R02111,R05196,R09995 RC00049 ko00000,ko00001,ko00002,ko01000,ko04147 CBM48,GH13,GH77 iJN678.malQ Bacteria 2GM5Z@201174,4CZC7@85004,COG1640@1,COG1640@2 NA|NA|NA G 4-alpha-glucanotransferase LPKNPDNH_00234 702459.BBPR_1572 8.9e-112 409.8 Bifidobacteriales Bacteria 2BMRI@1,2GMIA@201174,32GAY@2,4CZFZ@85004 NA|NA|NA LPKNPDNH_00235 702459.BBPR_1573 1.1e-113 416.0 Bifidobacteriales yigZ 2.1.1.45,3.4.13.9 ko:K00560,ko:K01271 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 2GMM4@201174,4CZH8@85004,COG1739@1,COG1739@2 NA|NA|NA S Uncharacterized protein family UPF0029 LPKNPDNH_00236 702459.BBPR_1574 3.6e-257 893.6 Bifidobacteriales ko:K07282 ko00000 Bacteria 2GK15@201174,4D081@85004,COG2843@1,COG2843@2 NA|NA|NA M Bacterial capsule synthesis protein PGA_cap LPKNPDNH_00238 702459.BBPR_1575 6e-241 839.7 Bifidobacteriales dinB 2.7.7.7 ko:K02346 ko00000,ko01000,ko03400 Bacteria 2GKBI@201174,4CZHT@85004,COG0389@1,COG0389@2 NA|NA|NA L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII LPKNPDNH_00239 702459.BBPR_1576 1.4e-225 788.5 Bifidobacteriales dapC Bacteria 2GJMI@201174,4CZ91@85004,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase class I and II LPKNPDNH_00240 398513.BBNG_01525 9e-61 239.2 Bifidobacteriales fdxA ko:K05524 ko00000 Bacteria 2IKVN@201174,4D11B@85004,COG1146@1,COG1146@2 NA|NA|NA C 4Fe-4S binding domain LPKNPDNH_00241 702459.BBPR_1578 9.7e-217 759.2 Bifidobacteriales murB GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0022603,GO:0022604,GO:0030203,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045229,GO:0048037,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0055114,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 iECED1_1282.ECED1_4683,iECUMN_1333.ECUMN_4498_AT6,iLF82_1304.LF82_1416,iNRG857_1313.NRG857_19845 Bacteria 2GIV2@201174,4CZSJ@85004,COG0812@1,COG0812@2 NA|NA|NA M Cell wall formation LPKNPDNH_00242 1435051.BMOU_1683 1.9e-25 120.9 Bifidobacteriales rpmG ko:K02913 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GQFG@201174,4D1EA@85004,COG0267@1,COG0267@2 NA|NA|NA J Ribosomal protein L33 LPKNPDNH_00246 398513.BBNG_01521 3.4e-56 224.2 Bacteria Bacteria COG0714@1,COG0714@2 NA|NA|NA KLT Associated with various cellular activities LPKNPDNH_00247 398513.BBNG_01520 3.1e-128 464.5 Bifidobacteriales bla1 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 2I9TI@201174,4D0DX@85004,COG2367@1,COG2367@2 NA|NA|NA V Beta-lactamase enzyme family LPKNPDNH_00248 398513.BBNG_01519 1.5e-46 191.8 Bifidobacteriales groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K04078 ko00000,ko03029,ko03110 Bacteria 2IKTH@201174,4D101@85004,COG0234@1,COG0234@2 NA|NA|NA O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter LPKNPDNH_00249 398513.BBNG_01518 7.2e-144 517.3 Bifidobacteriales Bacteria 2E03N@1,2GQE4@201174,32VSG@2,4CYUX@85004 NA|NA|NA LPKNPDNH_00250 702459.BBPR_1586 2.3e-149 534.6 Bifidobacteriales rimJ 2.3.1.128 ko:K03790 ko00000,ko01000,ko03009 Bacteria 2HAFI@201174,4CZRR@85004,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain LPKNPDNH_00251 398513.BBNG_01516 2e-120 438.3 Bifidobacteriales fthC 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 R02301 RC00183 ko00000,ko00001,ko01000 Bacteria 2IKWR@201174,4D12B@85004,COG0212@1,COG0212@2 NA|NA|NA H 5-formyltetrahydrofolate cyclo-ligase family LPKNPDNH_00252 398513.BBNG_01515 3.2e-38 163.7 Bifidobacteriales fmdB Bacteria 2IQHE@201174,4D1ES@85004,COG2331@1,COG2331@2 NA|NA|NA S Putative regulatory protein LPKNPDNH_00253 398513.BBNG_01514 1.6e-109 402.1 Bifidobacteriales flgA GO:0001539,GO:0006928,GO:0008150,GO:0009987,GO:0040011,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588 ko:K02279,ko:K02386 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Bacteria 2IIYF@201174,4D0YD@85004,COG1261@1,COG1261@2 NA|NA|NA NO SAF LPKNPDNH_00254 702459.BBPR_1590 9.6e-42 175.6 Bifidobacteriales Bacteria 2B18D@1,2GSR6@201174,31TNU@2,4D1ET@85004 NA|NA|NA LPKNPDNH_00255 702459.BBPR_1591 0.0 2338.1 Bifidobacteriales Bacteria 2GKJW@201174,4CYY9@85004,COG1112@1,COG1112@2 NA|NA|NA L Superfamily I DNA and RNA helicases and helicase subunits LPKNPDNH_00256 702459.BBPR_1592 1e-237 829.3 Bifidobacteriales Bacteria 2GIT6@201174,4CYX9@85004,COG1716@1,COG1716@2 NA|NA|NA T Forkhead associated domain LPKNPDNH_00258 1437610.BREU_0570 1.3e-37 162.5 Bifidobacteriales rplL GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K02935 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IKNW@201174,4D0W2@85004,COG0222@1,COG0222@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation LPKNPDNH_00259 398513.BBNG_01509 2.1e-88 331.6 Bifidobacteriales rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02864,ko:K02935 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GM0V@201174,4CZFP@85004,COG0244@1,COG0244@2 NA|NA|NA J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors LPKNPDNH_00260 398513.BBNG_01508 1.7e-182 645.2 Bacteria xynB2 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 Bacteria COG2755@1,COG2755@2 NA|NA|NA E lipolytic protein G-D-S-L family LPKNPDNH_00261 702459.BBPR_1596 0.0 3381.3 Actinobacteria guxA1 3.2.1.18,3.2.1.91 ko:K01186,ko:K19668,ko:K21449 ko00500,ko00511,ko00600,ko01100,ko02020,ko04142,map00500,map00511,map00600,map01100,map02020,map04142 R02886,R04018,R11308 RC00028,RC00077,RC00799 ko00000,ko00001,ko01000,ko02000,ko02042 1.B.40.2 GH33,GH6 Bacteria 2GUR0@201174,COG1196@1,COG1196@2,COG3934@1,COG3934@2,COG4409@1,COG4409@2,COG5492@1,COG5492@2 NA|NA|NA G BNR repeat-like domain LPKNPDNH_00263 398513.BBNG_01505 8.8e-222 776.2 Bifidobacteriales pbuO ko:K06901 ko00000,ko02000 2.A.1.40 Bacteria 2GKYD@201174,4CZHD@85004,COG2252@1,COG2252@2 NA|NA|NA S Permease family LPKNPDNH_00264 398513.BBNG_01504 1.4e-12 77.4 Bifidobacteriales gmk 1.1.1.23,2.7.4.8 ko:K00013,ko:K00942 ko00230,ko00340,ko01100,ko01110,ko01230,map00230,map00340,map01100,map01110,map01230 M00026,M00050 R00332,R01158,R01163,R02090,R03012 RC00002,RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 Bacteria 2HTNX@201174,4D0CP@85004,COG2852@1,COG2852@2 NA|NA|NA S Protein conserved in bacteria LPKNPDNH_00265 398513.BBNG_01504 3e-170 604.4 Bifidobacteriales gmk 1.1.1.23,2.7.4.8 ko:K00013,ko:K00942 ko00230,ko00340,ko01100,ko01110,ko01230,map00230,map00340,map01100,map01110,map01230 M00026,M00050 R00332,R01158,R01163,R02090,R03012 RC00002,RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 Bacteria 2HTNX@201174,4D0CP@85004,COG2852@1,COG2852@2 NA|NA|NA S Protein conserved in bacteria LPKNPDNH_00266 398513.BBNG_01503 3.6e-148 530.8 Bifidobacteriales pstB 3.6.3.27 ko:K02036 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 Bacteria 2GJQ3@201174,4CYVE@85004,COG1117@1,COG1117@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system LPKNPDNH_00267 702459.BBPR_1601 6.2e-180 636.7 Bifidobacteriales pstA GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0010921,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0019220,GO:0019222,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0031323,GO:0033554,GO:0034220,GO:0035303,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0098656,GO:0098660,GO:0098661 ko:K02037,ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 iJN746.PP_2658,iPC815.YPO4115,iYL1228.KPN_04131,iZ_1308.Z5217 Bacteria 2I2F2@201174,4D2UW@85004,COG0581@1,COG0581@2 NA|NA|NA P Phosphate transport system permease LPKNPDNH_00268 398513.BBNG_01501 3.8e-171 607.4 Bifidobacteriales pstC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0009314,GO:0009628,GO:0010921,GO:0015698,GO:0016020,GO:0016021,GO:0019220,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0034220,GO:0035303,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0098656,GO:0098660,GO:0098661 ko:K02037,ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 iAF987.Gmet_2702,ic_1306.c4652 Bacteria 2GJDA@201174,4CYV0@85004,COG0573@1,COG0573@2 NA|NA|NA P probably responsible for the translocation of the substrate across the membrane LPKNPDNH_00269 702459.BBPR_1603 3e-172 611.3 Bifidobacteriales pstS ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 2GJXD@201174,4CYTZ@85004,COG0226@1,COG0226@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import LPKNPDNH_00270 398513.BBNG_01499 1.4e-127 462.2 Bifidobacteriales Bacteria 2GKFS@201174,4CZTX@85004,COG0745@1,COG0745@2 NA|NA|NA KT Transcriptional regulatory protein, C terminal LPKNPDNH_00271 702459.BBPR_1605 8.5e-246 855.9 Bifidobacteriales senX3 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564 2.7.13.3 ko:K07636,ko:K07768,ko:K11383 ko02020,map02020 M00434,M00443,M00505 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2GJY7@201174,4CZ42@85004,COG5002@1,COG5002@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain LPKNPDNH_00272 398513.BBNG_01497 1.9e-124 451.8 Bifidobacteriales mtnN 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 Bacteria 2I8GZ@201174,4CYTM@85004,COG0775@1,COG0775@2 NA|NA|NA E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively LPKNPDNH_00273 398513.BBNG_01496 1.7e-240 838.2 Bifidobacteriales aroG GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2375,iAPECO1_1312.APECO1_3932,iECNA114_1301.ECNA114_0684,iECOK1_1307.ECOK1_2946,iECS88_1305.ECS88_2787,iECSF_1327.ECSF_0680,iEcSMS35_1347.EcSMS35_0777,iHN637.CLJU_RS07240,iLF82_1304.LF82_0146,iNRG857_1313.NRG857_03335,iSbBS512_1146.SbBS512_E1908,iUMN146_1321.UM146_03705,iUTI89_1310.UTI89_C2934,iYL1228.KPN_00758 Bacteria 2GMVF@201174,4CZ7I@85004,COG0722@1,COG0722@2 NA|NA|NA E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) LPKNPDNH_00274 398513.BBNG_01495 9.7e-109 399.4 Bifidobacteriales ko:K04096 ko00000 Bacteria 2II9U@201174,4D0Y5@85004,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor LPKNPDNH_00275 398513.BBNG_01494 3.4e-242 844.0 Bifidobacteriales Bacteria 2I8QF@201174,4CZF1@85004,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily LPKNPDNH_00276 702459.BBPR_1610 3.3e-219 767.3 Bifidobacteriales aroG GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2375,iAPECO1_1312.APECO1_3932,iECNA114_1301.ECNA114_0684,iECOK1_1307.ECOK1_2946,iECS88_1305.ECS88_2787,iECSF_1327.ECSF_0680,iEcSMS35_1347.EcSMS35_0777,iHN637.CLJU_RS07240,iLF82_1304.LF82_0146,iNRG857_1313.NRG857_03335,iSbBS512_1146.SbBS512_E1908,iUMN146_1321.UM146_03705,iUTI89_1310.UTI89_C2934,iYL1228.KPN_00758 Bacteria 2GMVF@201174,4CZMR@85004,COG0722@1,COG0722@2 NA|NA|NA E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) LPKNPDNH_00277 702459.BBPR_1611 2.3e-166 591.7 Bifidobacteriales ko:K03646 ko00000,ko02000 2.C.1.2 Bacteria 2GJ38@201174,4CYVR@85004,COG2356@1,COG2356@2,COG3064@1,COG3064@2 NA|NA|NA L Excalibur calcium-binding domain LPKNPDNH_00278 702459.BBPR_1612 1.6e-268 931.4 Bifidobacteriales pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 ko00000,ko01000,ko01002 Bacteria 2GNYU@201174,4CZDZ@85004,COG3579@1,COG3579@2 NA|NA|NA E Peptidase C1-like family LPKNPDNH_00279 702459.BBPR_1613 7.4e-54 218.4 Bifidobacteriales Bacteria 2HZ99@201174,4CZ0S@85004,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation LPKNPDNH_00280 398513.BBNG_01489 8e-128 463.0 Bifidobacteriales pcp GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 3.4.19.3 ko:K01304 ko00000,ko01000,ko01002 Bacteria 2GN39@201174,4CZ57@85004,COG2039@1,COG2039@2 NA|NA|NA O Removes 5-oxoproline from various penultimate amino acid residues except L-proline LPKNPDNH_00281 398513.BBNG_01488 1.1e-144 519.2 Bifidobacteriales ispD GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.405,2.7.7.40,2.7.7.60,4.6.1.12 ko:K00991,ko:K12506,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 M00096 R01525,R02921,R05633,R05637 RC00002,RC00089,RC01440 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNHP@201174,4CYVZ@85004,COG1211@1,COG1211@2 NA|NA|NA I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) LPKNPDNH_00282 702459.BBPR_1617 1.6e-185 655.2 Bifidobacteriales yfiH GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0030312,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114,GO:0071944 ko:K05810 ko00000,ko01000 Bacteria 2GN1M@201174,4CZBI@85004,COG1496@1,COG1496@2 NA|NA|NA Q Multi-copper polyphenol oxidoreductase laccase LPKNPDNH_00283 398513.BBNG_01486 0.0 1112.8 Bifidobacteriales yegQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Bacteria 2GKTB@201174,4CZA1@85004,COG0826@1,COG0826@2 NA|NA|NA O Peptidase family U32 C-terminal domain LPKNPDNH_00284 398513.BBNG_01485 1.7e-96 358.6 Bifidobacteriales Bacteria 2GMZX@201174,4D0DN@85004,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives IS30 family LPKNPDNH_00285 398513.BBNG_01484 4.6e-168 597.0 Bifidobacteriales 1.1.1.65 ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 R01708 RC00116 ko00000,ko00001,ko01000 Bacteria 2GJ6R@201174,4CZB6@85004,COG0667@1,COG0667@2 NA|NA|NA C Oxidoreductase, aldo keto reductase family protein LPKNPDNH_00286 702459.BBPR_1622 6.3e-41 172.9 Bifidobacteriales nrdH ko:K06191 ko00000 Bacteria 2IRCP@201174,4D17U@85004,COG0695@1,COG0695@2 NA|NA|NA O Glutaredoxin LPKNPDNH_00287 702459.BBPR_1623 5.6e-98 363.6 Bifidobacteriales nrdI ko:K03647 ko00000 Bacteria 2IM4D@201174,4D0XV@85004,COG1780@1,COG1780@2 NA|NA|NA F Probably involved in ribonucleotide reductase function LPKNPDNH_00288 398513.BBNG_01481 0.0 1458.0 Bifidobacteriales nrdE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0015949,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 iAPECO1_1312.APECO1_3846,iYO844.BSU17380 Bacteria 2GKX9@201174,4CZF3@85004,COG0209@1,COG0209@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides LPKNPDNH_00289 398513.BBNG_01480 9.1e-189 666.0 Bifidobacteriales nrdF GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0030145,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 iECNA114_1301.ECNA114_2708,iECSF_1327.ECSF_2473,iSFV_1184.SFV_2827,iSF_1195.SF2704,iSFxv_1172.SFxv_2966,iS_1188.S2890 Bacteria 2GK46@201174,4CYQ2@85004,COG0208@1,COG0208@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides LPKNPDNH_00290 1437609.BCAL_1216 9.2e-74 283.1 Bifidobacteriales megL 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 ko:K01739,ko:K01758,ko:K01760,ko:K01761 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00338 R00654,R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366 RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GNZH@201174,4D04I@85004,COG0626@1,COG0626@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme LPKNPDNH_00291 702459.BBPR_1627 0.0 1399.0 Bifidobacteriales Bacteria 2HZD2@201174,4CZV5@85004,COG4907@1,COG4907@2 NA|NA|NA S Predicted membrane protein (DUF2207) LPKNPDNH_00292 398513.BBNG_01477 1.4e-93 349.0 Bifidobacteriales lemA ko:K03744 ko00000 Bacteria 2GPS4@201174,4CZE2@85004,COG1704@1,COG1704@2 NA|NA|NA S LemA family LPKNPDNH_00293 702459.BBPR_1629 1.5e-40 171.8 Bacteria Bacteria COG1609@1,COG1609@2 NA|NA|NA K purine nucleotide biosynthetic process LPKNPDNH_00294 398513.BBNG_01476 2.6e-151 541.2 Bacteria xylR GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 ko:K02529 ko00000,ko03000 Bacteria COG1609@1,COG1609@2 NA|NA|NA K purine nucleotide biosynthetic process LPKNPDNH_00295 398513.BBNG_01474 0.0 1504.2 Bifidobacteriales pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 2GIT2@201174,4CYSW@85004,COG1185@1,COG1185@2 NA|NA|NA J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction LPKNPDNH_00296 398513.BBNG_01472 3e-41 174.1 Bifidobacteriales rpsO GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02956 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQA0@201174,4D10E@85004,COG0184@1,COG0184@2 NA|NA|NA J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome LPKNPDNH_00297 702459.BBPR_1634 8.9e-119 433.0 Bifidobacteriales Bacteria 2B37S@1,2IDBE@201174,31VVT@2,4CZJV@85004 NA|NA|NA LPKNPDNH_00298 702459.BBPR_1635 0.0 2116.7 Actinobacteria nagH 3.2.1.35,3.2.1.52 ko:K01197,ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00076,M00077,M00079 R00022,R06004,R07824,R07825,R10905,R11316 RC00049 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042,ko03110 GH20 Bacteria 2GM4H@201174,COG3525@1,COG3525@2 NA|NA|NA G beta-N-acetylglucosaminidase LPKNPDNH_00300 398513.BBNG_01469 1.3e-162 578.9 Bifidobacteriales birA GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 2.7.1.33,6.3.4.15 ko:K01947,ko:K03524 ko00770,ko00780,ko01100,map00770,map00780,map01100 M00120 R01074,R02971,R03018,R04391,R05145 RC00002,RC00017,RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko00002,ko01000,ko03000 Bacteria 2GN8Q@201174,4D0R8@85004,COG0340@1,COG0340@2 NA|NA|NA H Biotin/lipoate A/B protein ligase family LPKNPDNH_00301 702459.BBPR_1637 3.2e-98 364.4 Bifidobacteriales acpS GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 2.7.8.7,3.2.1.52 ko:K00997,ko:K01207 ko00520,ko00531,ko00770,ko01100,ko01501,map00520,map00531,map00770,map01100,map01501 M00628 R00022,R01625,R05963,R07809,R07810,R10831 RC00002,RC00049 ko00000,ko00001,ko00002,ko01000 Bacteria 2HZNB@201174,4D10J@85004,COG0736@1,COG0736@2 NA|NA|NA I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein LPKNPDNH_00302 702459.BBPR_1638 0.0 6018.3 Bifidobacteriales fas 2.3.1.179 ko:K09458,ko:K11533 ko00061,ko00780,ko01100,ko01212,ko04931,map00061,map00780,map01100,map01212,map04931 M00082,M00083,M00572 R01624,R01626,R04355,R04428,R04429,R04533,R04534,R04535,R04536,R04537,R04543,R04544,R04566,R04568,R04724,R04726,R04952,R04953,R04954,R04955,R04957,R04958,R04960,R04961,R04963,R04964,R04965,R04966,R04968,R04969,R07762,R07763,R07764,R07765,R10115,R10119,R10700 RC00004,RC00029,RC00039,RC00052,RC00076,RC00117,RC00831,RC01095,RC02727,RC02728,RC02729,RC02857,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2GIY4@201174,4CYXJ@85004,COG0304@1,COG0304@2,COG0331@1,COG0331@2,COG2030@1,COG2030@2,COG4981@1,COG4981@2 NA|NA|NA I Beta-ketoacyl synthase, C-terminal domain LPKNPDNH_00303 702459.BBPR_1639 7.2e-308 1062.4 Bifidobacteriales pccB Bacteria 2GIRU@201174,4CYSI@85004,COG4799@1,COG4799@2 NA|NA|NA I Carboxyl transferase domain LPKNPDNH_00304 398513.BBNG_01465 0.0 1258.0 Bifidobacteriales accA 6.3.4.14,6.4.1.2,6.4.1.3 ko:K11263 ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00741 R00742,R01859,R04385 RC00040,RC00097,RC00253,RC00367,RC00609 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIZP@201174,4CYU4@85004,COG4770@1,COG4770@2 NA|NA|NA I Carbamoyl-phosphate synthase L chain, ATP binding domain protein LPKNPDNH_00305 398513.BBNG_01464 4.2e-93 347.4 Bifidobacteriales bioY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03523 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 Bacteria 2GJ53@201174,4D0BB@85004,COG1268@1,COG1268@2 NA|NA|NA S BioY family LPKNPDNH_00306 398513.BBNG_01463 4e-153 547.4 Bifidobacteriales birA GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 2.7.1.33,6.3.4.15 ko:K01947,ko:K03524 ko00770,ko00780,ko01100,map00770,map00780,map01100 M00120 R01074,R02971,R03018,R04391,R05145 RC00002,RC00017,RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko00002,ko01000,ko03000 Bacteria 2GN8Q@201174,4D0R8@85004,COG0340@1,COG0340@2 NA|NA|NA H Biotin/lipoate A/B protein ligase family LPKNPDNH_00307 702459.BBPR_1643 0.0 1358.6 Bifidobacteriales Bacteria 2DX0J@1,2H683@201174,342TV@2,4CZAG@85004 NA|NA|NA LPKNPDNH_00308 398513.BBNG_01461 5.9e-146 523.5 Bifidobacteriales Bacteria 2GN0S@201174,4CYXU@85004,COG2508@1,COG2508@2 NA|NA|NA QT PucR C-terminal helix-turn-helix domain LPKNPDNH_00309 702459.BBPR_1645 9.5e-132 476.1 Bifidobacteriales nucS ko:K07503 ko00000,ko01000 Bacteria 2GIYB@201174,4CYXA@85004,COG1637@1,COG1637@2 NA|NA|NA L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures LPKNPDNH_00310 702459.BBPR_1646 8.7e-50 202.6 Bifidobacteriales atpC GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 2HZPJ@201174,4D16F@85004,COG0355@1,COG0355@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane LPKNPDNH_00311 398513.BBNG_01457 9.5e-283 978.8 Bifidobacteriales atpD GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 Bacteria 2GIY6@201174,4CZGY@85004,COG0055@1,COG0055@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits LPKNPDNH_00312 398513.BBNG_01456 2.7e-166 591.3 Bifidobacteriales atpG GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iLJ478.TM1611,iSSON_1240.SSON_3886,iYL1228.KPN_04138 Bacteria 2GJ7Q@201174,4CYVJ@85004,COG0224@1,COG0224@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex LPKNPDNH_00313 398513.BBNG_01455 0.0 1105.1 Bifidobacteriales atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187 Bacteria 2GJRJ@201174,4CZI7@85004,COG0056@1,COG0056@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit LPKNPDNH_00314 702459.BBPR_1650 4.1e-150 537.3 Bifidobacteriales atpH ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 2GMJ5@201174,4CZ9V@85004,COG0712@1,COG0712@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation LPKNPDNH_00315 398513.BBNG_01453 4.6e-62 244.2 Bifidobacteriales atpF ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 2GJS4@201174,4CYY5@85004,COG0711@1,COG0711@2 NA|NA|NA C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) LPKNPDNH_00316 398513.BBNG_01452 1.2e-30 138.7 Bifidobacteriales atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 2GQI6@201174,4D16J@85004,COG0636@1,COG0636@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation LPKNPDNH_00318 398513.BBNG_01451 6e-146 523.5 Bifidobacteriales atpB ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 Bacteria 2H3PR@201174,4CYZD@85004,COG0356@1,COG0356@2 NA|NA|NA C it plays a direct role in the translocation of protons across the membrane LPKNPDNH_00319 398513.BBNG_01450 1.2e-207 728.8 Bifidobacteriales metAA GO:0003674,GO:0003824,GO:0008374,GO:0008899,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0881 Bacteria 2GK5E@201174,4CZRK@85004,COG1897@1,COG1897@2 NA|NA|NA E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine LPKNPDNH_00321 702459.BBPR_1656 1e-44 185.7 Bifidobacteriales Bacteria 2E3TC@1,2GU2H@201174,32DPP@2,4D1HW@85004 NA|NA|NA LPKNPDNH_00322 702459.BBPR_1657 0.0 1446.0 Bifidobacteriales Bacteria 2H7AK@201174,4CZMA@85004,COG5624@1,COG5624@2 NA|NA|NA K RNA polymerase II activating transcription factor binding LPKNPDNH_00323 702459.BBPR_1658 0.0 1457.2 Bifidobacteriales glgE 2.4.99.16 ko:K16147 ko00500,ko01100,map00500,map01100 R09994 ko00000,ko00001,ko01000 GH13 Bacteria 2GJKR@201174,4CZSK@85004,COG0366@1,COG0366@2 NA|NA|NA G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB LPKNPDNH_00324 398513.BBNG_01444 5.2e-92 343.6 Bifidobacteriales ppa GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944 3.6.1.1 ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 iNJ661.Rv3628 Bacteria 2GM7F@201174,4CYWS@85004,COG0221@1,COG0221@2 NA|NA|NA C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions LPKNPDNH_00326 702459.BBPR_1660 1.3e-102 379.0 Bifidobacteriales mntP Bacteria 2GNBU@201174,4D01X@85004,COG1971@1,COG1971@2 NA|NA|NA P Probably functions as a manganese efflux pump LPKNPDNH_00327 398513.BBNG_01442 1.4e-125 455.7 Bifidobacteriales Bacteria 2A0I6@1,2GJ8M@201174,30NNB@2,4D0ZN@85004 NA|NA|NA LPKNPDNH_00328 398513.BBNG_01441 1.8e-133 481.9 Bifidobacteriales Bacteria 2GJGU@201174,4CZB9@85004,COG0745@1,COG0745@2 NA|NA|NA KT Transcriptional regulatory protein, C terminal LPKNPDNH_00329 702459.BBPR_1663 1.5e-120 438.7 Bifidobacteriales nth GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJ01@201174,4CZ31@85004,COG0177@1,COG0177@2 NA|NA|NA L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate LPKNPDNH_00330 398513.BBNG_01439 4.3e-294 1016.5 Bifidobacteriales ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GM5G@201174,4CYUZ@85004,COG0747@1,COG0747@2 NA|NA|NA E Bacterial extracellular solute-binding proteins, family 5 Middle LPKNPDNH_00331 398513.BBNG_01438 0.0 1886.3 Bifidobacteriales valS 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GK8H@201174,4CYVG@85004,COG0525@1,COG0525@2 NA|NA|NA J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner LPKNPDNH_00332 702459.BBPR_1666 0.0 1154.4 Bifidobacteriales ko:K01421,ko:K21449 ko00000,ko02000 1.B.40.2 Bacteria 2I9PN@201174,4CZC2@85004,COG1511@1,COG1511@2 NA|NA|NA S domain protein LPKNPDNH_00333 398513.BBNG_01436 4.7e-73 280.4 Bifidobacteriales tyrA 5.4.99.5 ko:K04092 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 Bacteria 2IQ46@201174,4D12A@85004,COG1605@1,COG1605@2 NA|NA|NA E Chorismate mutase type II LPKNPDNH_00334 702459.BBPR_1668 9.1e-90 336.3 Bifidobacteriales lrp_3 ko:K03719 ko00000,ko03000,ko03036 Bacteria 2GK3G@201174,4D0XT@85004,COG1522@1,COG1522@2 NA|NA|NA K helix_turn_helix ASNC type LPKNPDNH_00335 398513.BBNG_01434 1.5e-219 768.5 Bifidobacteriales ko:K10907 ko00000,ko01000,ko01007 Bacteria 2GJ7R@201174,4CYVP@85004,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase class I and II LPKNPDNH_00336 398513.BBNG_01433 0.0 1083.9 Bifidobacteriales rho GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Bacteria 2GIWY@201174,4CZ2Z@85004,COG1158@1,COG1158@2 NA|NA|NA K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template LPKNPDNH_00337 398513.BBNG_01432 0.0 1111.7 Bifidobacteriales 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 Bacteria 2HZ9K@201174,4CZ3Z@85004,COG1232@1,COG1232@2 NA|NA|NA H Flavin containing amine oxidoreductase LPKNPDNH_00338 398513.BBNG_01431 2.5e-52 211.1 Bifidobacteriales GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2AFXT@1,2IKPZ@201174,3161G@2,4D0UV@85004 NA|NA|NA S Protein of unknown function (DUF2469) LPKNPDNH_00339 398513.BBNG_01430 1.7e-198 698.4 Bifidobacteriales 2.3.1.57 ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 M00135 R01154 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 2I2GV@201174,4CYPW@85004,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain LPKNPDNH_00340 398513.BBNG_01429 1.4e-286 991.5 Bifidobacteriales gatB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 2GJJH@201174,4CYUY@85004,COG0064@1,COG0064@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) LPKNPDNH_00341 398513.BBNG_01428 1.1e-289 1001.9 Bifidobacteriales gatA GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 2GJK5@201174,4CZ1X@85004,COG0154@1,COG0154@2 NA|NA|NA F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) LPKNPDNH_00342 398513.BBNG_01427 6.2e-48 196.4 Bifidobacteriales gatC GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 2IQJN@201174,4D10U@85004,COG0721@1,COG0721@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) LPKNPDNH_00343 398513.BBNG_01426 3.7e-82 310.8 Bifidobacteriales ko:K01990,ko:K09384 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GJDP@201174,4D00Y@85004,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter LPKNPDNH_00344 702459.BBPR_1679 1e-60 239.2 Bifidobacteriales ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GJDP@201174,4D00Y@85004,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter LPKNPDNH_00345 398513.BBNG_01424 5.9e-155 553.5 Bifidobacteriales spoU 2.1.1.185 ko:K03218 ko00000,ko01000,ko03009 Bacteria 2GM1A@201174,4CZE8@85004,COG0566@1,COG0566@2 NA|NA|NA J RNA methyltransferase TrmH family LPKNPDNH_00346 702459.BBPR_1681 1.6e-129 468.8 Bifidobacteriales pyrE 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 iJN678.umpS Bacteria 2HZDS@201174,4CZZ6@85004,COG0461@1,COG0461@2 NA|NA|NA F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) LPKNPDNH_00347 702459.BBPR_1682 2.9e-214 751.1 Bifidobacteriales rmuC ko:K09760 ko00000 Bacteria 2GP4U@201174,4CZA5@85004,COG1322@1,COG1322@2 NA|NA|NA S RmuC family LPKNPDNH_00348 398513.BBNG_01421 9.6e-43 179.1 Bifidobacteriales csoR GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0042221,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0046688,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K21600 ko00000,ko03000 Bacteria 2IQAC@201174,4D1A2@85004,COG1937@1,COG1937@2 NA|NA|NA S Metal-sensitive transcriptional repressor LPKNPDNH_00349 398513.BBNG_01420 0.0 1649.0 Bifidobacteriales pacS GO:0000041,GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0016020,GO:0030001,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0071944 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 2GIRF@201174,4CZ24@85004,COG2217@1,COG2217@2 NA|NA|NA P E1-E2 ATPase LPKNPDNH_00350 398513.BBNG_01419 0.0 1172.9 Bifidobacteriales ubiB ko:K03688 ko00000 Bacteria 2GJQ6@201174,4CZ45@85004,COG0661@1,COG0661@2 NA|NA|NA S ABC1 family LPKNPDNH_00351 398513.BBNG_01418 3.5e-19 100.9 Bifidobacteriales Bacteria 2GS3M@201174,4D1FE@85004,COG3937@1,COG3937@2 NA|NA|NA S granule-associated protein LPKNPDNH_00352 702459.BBPR_1687 7.5e-143 513.1 Bifidobacteriales cobQ ko:K07009 ko00000 iSB619.SA_RS09800 Bacteria 2GKPV@201174,4CZJ1@85004,COG3442@1,COG3442@2 NA|NA|NA S CobB/CobQ-like glutamine amidotransferase domain LPKNPDNH_00353 398513.BBNG_01416 2.5e-281 974.2 Bifidobacteriales murD 3.4.21.10,6.3.2.13,6.3.2.9 ko:K01317,ko:K01925,ko:K01928,ko:K01932 ko00300,ko00471,ko00550,ko01100,map00300,map00471,map00550,map01100 R02783,R02788 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01002,ko01011,ko04131 Bacteria 2GK18@201174,4CYTP@85004,COG0771@1,COG0771@2 NA|NA|NA M Domain of unknown function (DUF1727) LPKNPDNH_00354 398513.BBNG_01415 7.5e-258 896.0 Bifidobacteriales dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Bacteria 2GKXQ@201174,4CYY3@85004,COG0305@1,COG0305@2 NA|NA|NA L Participates in initiation and elongation during chromosome replication LPKNPDNH_00355 702459.BBPR_1690 3.5e-250 870.5 Bifidobacteriales dinF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03327 ko00000,ko02000 2.A.66.1 Bacteria 2GJE3@201174,4CZ75@85004,COG0534@1,COG0534@2 NA|NA|NA V MatE LPKNPDNH_00356 398513.BBNG_01413 3.5e-20 104.4 Bifidobacteriales 2.7.7.19,2.7.7.59 ko:K00970,ko:K00990 ko02020,ko03018,map02020,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 2GMKT@201174,4D07P@85004,COG2844@1,COG2844@2 NA|NA|NA O Nucleotidyltransferase domain LPKNPDNH_00357 702459.BBPR_1691 0.0 1246.9 Bifidobacteriales 2.7.7.19,2.7.7.59 ko:K00970,ko:K00990 ko02020,ko03018,map02020,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 2GMKT@201174,4D07P@85004,COG2844@1,COG2844@2 NA|NA|NA O Nucleotidyltransferase domain LPKNPDNH_00358 158787.BSCA_0063 1e-54 219.2 Bifidobacteriales glnB ko:K04751 ko02020,map02020 ko00000,ko00001 Bacteria 2IKN1@201174,4D0VD@85004,COG0347@1,COG0347@2 NA|NA|NA K Nitrogen regulatory protein P-II LPKNPDNH_00359 702459.BBPR_1693 3.8e-219 767.3 Bifidobacteriales amt ko:K03320 ko00000,ko02000 1.A.11 Bacteria 2GIZK@201174,4CZA0@85004,COG0004@1,COG0004@2 NA|NA|NA U Ammonium Transporter Family LPKNPDNH_00360 702459.BBPR_1694 6.2e-203 713.4 Bifidobacteriales ftsY GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 Bacteria 2GJQH@201174,4CZZX@85004,COG0552@1,COG0552@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) LPKNPDNH_00362 398513.BBNG_01409 1.2e-116 426.0 Bifidobacteriales icaR Bacteria 2GMBW@201174,4CYUD@85004,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family LPKNPDNH_00363 398513.BBNG_01408 1.5e-197 695.3 Bifidobacteriales XK27_01805 Bacteria 2GMDK@201174,4CZIS@85004,COG0463@1,COG0463@2 NA|NA|NA M Glycosyltransferase like family 2 LPKNPDNH_00364 702459.BBPR_1698 0.0 1357.4 Bifidobacteriales Bacteria 28J61@1,2HZIR@201174,2Z91S@2,4D0KC@85004 NA|NA|NA S Glycosyl hydrolases related to GH101 family, GH129 LPKNPDNH_00365 702459.BBPR_1699 1.4e-305 1054.7 Bifidobacteriales pepD ko:K08659 ko00000,ko01000,ko01002 Bacteria 2GM80@201174,4CYT0@85004,COG4690@1,COG4690@2 NA|NA|NA E Peptidase family C69 LPKNPDNH_00367 1437608.BBIA_1531 2.9e-19 101.7 Bifidobacteriales XK26_04485 ko:K16785 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2IDZ2@201174,4D0CV@85004,COG0619@1,COG0619@2 NA|NA|NA P Cobalt transport protein LPKNPDNH_00368 398513.BBNG_01404 1.1e-68 265.8 Bifidobacteriales XK26_04485 ko:K16785 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2IDZ2@201174,4D0CV@85004,COG0619@1,COG0619@2 NA|NA|NA P Cobalt transport protein LPKNPDNH_00369 702459.BBPR_1702 2e-82 311.6 Bifidobacteriales Bacteria 2A0RN@1,2IH59@201174,30NW7@2,4D0T0@85004 NA|NA|NA LPKNPDNH_00370 398513.BBNG_01402 0.0 1133.6 Bifidobacteriales ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2GITR@201174,4CZWS@85004,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region LPKNPDNH_00371 398513.BBNG_01401 1.8e-301 1041.2 Bifidobacteriales ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2GITR@201174,4CYYV@85004,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter, ATP-binding protein LPKNPDNH_00372 398513.BBNG_01400 2.7e-82 311.2 Bifidobacteriales Bacteria 2IQ1Z@201174,4D13P@85004,COG1846@1,COG1846@2 NA|NA|NA K Winged helix DNA-binding domain LPKNPDNH_00373 398513.BBNG_01398 5.8e-305 1052.7 Bifidobacteriales Bacteria 2IMAM@201174,4D2UC@85004,COG4932@1,COG4932@2 NA|NA|NA M LPXTG cell wall anchor motif LPKNPDNH_00374 702459.BBPR_1708 0.0 1414.1 Bacteria ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria COG2885@1,COG2885@2 NA|NA|NA M chlorophyll binding LPKNPDNH_00375 398513.BBNG_01395 2e-180 638.3 Bifidobacteriales 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria 2GNWT@201174,4CZMM@85004,COG3764@1,COG3764@2 NA|NA|NA M Sortase family LPKNPDNH_00377 702459.BBPR_1710 4.7e-162 577.0 Bifidobacteriales Bacteria 2GNWG@201174,4CZY9@85004,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase LPKNPDNH_00378 398513.BBNG_01393 3.5e-241 840.5 Bifidobacteriales Bacteria 2IBSV@201174,4D05G@85004,COG4905@1,COG4905@2 NA|NA|NA S Putative ABC-transporter type IV LPKNPDNH_00379 398513.BBNG_01392 7e-81 306.6 Bifidobacteriales Bacteria 2C3VM@1,2IHI9@201174,32RCV@2,4D0P4@85004 NA|NA|NA LPKNPDNH_00380 398513.BBNG_01391 5.8e-33 146.4 Bacteria Bacteria COG0561@1,COG0561@2 NA|NA|NA Q phosphatase activity LPKNPDNH_00381 398513.BBNG_01390 1.2e-295 1021.5 Bifidobacteriales bglA GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008422,GO:0015926,GO:0016787,GO:0016798,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901657 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 iEC55989_1330.EC55989_3188,iSSON_1240.SSON_3054,iUTI89_1310.UTI89_C1752 Bacteria 2GJAF@201174,4CYPX@85004,COG2723@1,COG2723@2 NA|NA|NA G Glycosyl hydrolase family 1 LPKNPDNH_00382 1437609.BCAL_0217 3.3e-42 177.6 Bifidobacteriales celC 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 Bacteria 2GPKA@201174,4D1CF@85004,COG1447@1,COG1447@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIA subunit LPKNPDNH_00383 398513.BBNG_01388 1.2e-48 198.7 Bifidobacteriales celA 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 Bacteria 2ISXW@201174,4D17Z@85004,COG1440@1,COG1440@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit LPKNPDNH_00384 398513.BBNG_01387 7.3e-250 869.4 Bifidobacteriales gmuC ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 Bacteria 2ID55@201174,4D00N@85004,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane LPKNPDNH_00385 702459.BBPR_1718 4.6e-67 260.4 Bifidobacteriales Bacteria 2IDRU@201174,4D0ZK@85004,COG0561@1,COG0561@2 NA|NA|NA S haloacid dehalogenase-like hydrolase LPKNPDNH_00386 702459.BBPR_1720 3.6e-131 474.2 Bifidobacteriales yydK ko:K03489,ko:K03710 ko00000,ko03000 Bacteria 2GJZ1@201174,4CZ6A@85004,COG2188@1,COG2188@2 NA|NA|NA K UTRA LPKNPDNH_00387 702459.BBPR_1721 1.3e-70 272.7 Bifidobacteriales ko:K03612 ko00000 Bacteria 2IQ4E@201174,4D0YM@85004,COG3976@1,COG3976@2 NA|NA|NA S FMN_bind LPKNPDNH_00388 398513.BBNG_01383 1.8e-147 528.5 Bifidobacteriales macB ko:K02003,ko:K09810 ko02010,map02010 M00255,M00258 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.125 Bacteria 2GK3I@201174,4CYTA@85004,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein LPKNPDNH_00389 398513.BBNG_01382 3.9e-195 687.6 Bifidobacteriales Z012_06715 ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GIRW@201174,4CZEZ@85004,COG0577@1,COG0577@2 NA|NA|NA V FtsX-like permease family LPKNPDNH_00390 398513.BBNG_01381 9.7e-223 779.2 Bifidobacteriales macB_2 ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2I91N@201174,4CZGK@85004,COG0577@1,COG0577@2 NA|NA|NA V ABC transporter permease LPKNPDNH_00391 702459.BBPR_1725 1.6e-233 815.1 Bifidobacteriales Bacteria 2GMS6@201174,4CZ19@85004,COG4393@1,COG4393@2 NA|NA|NA S Predicted membrane protein (DUF2318) LPKNPDNH_00392 398513.BBNG_01379 5.4e-108 397.1 Bifidobacteriales tpd ko:K07230 ko00000,ko02000 2.A.108.2.10,2.A.108.2.4,2.A.108.2.9 Bacteria 2GNAD@201174,4CZCG@85004,COG3470@1,COG3470@2 NA|NA|NA P Fe2+ transport protein LPKNPDNH_00393 398513.BBNG_01378 3.9e-307 1060.1 Bifidobacteriales efeU_1 ko:K07243 ko00000,ko02000 2.A.108.1,2.A.108.2 Bacteria 2GJ22@201174,4D01C@85004,COG0672@1,COG0672@2 NA|NA|NA P Iron permease FTR1 family LPKNPDNH_00394 398513.BBNG_01377 2e-18 97.8 Bifidobacteriales ko:K08152 ko00000,ko02000 2.A.1.2 Bacteria 2HZ98@201174,4CZ0N@85004,COG2211@1,COG2211@2 NA|NA|NA G MFS/sugar transport protein LPKNPDNH_00395 398513.BBNG_01376 1.1e-200 705.7 Bifidobacteriales apbE 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria 2H8YU@201174,4CZW7@85004,COG1477@1,COG1477@2 NA|NA|NA H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein LPKNPDNH_00396 1690.BPSG_1178 2e-56 225.7 Bifidobacteriales Bacteria 2GN3K@201174,4D1MZ@85004,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family LPKNPDNH_00397 398513.BBNG_01374 1.2e-289 1001.9 Bifidobacteriales ptsI 2.7.3.9 ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 8.A.7 Bacteria 2GIZZ@201174,4CZ52@85004,COG1080@1,COG1080@2 NA|NA|NA G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) LPKNPDNH_00398 398513.BBNG_01373 5e-38 163.3 Bifidobacteriales ptsH ko:K11189 ko00000,ko02000 4.A.2.1 Bacteria 2GQX6@201174,4D19B@85004,COG1925@1,COG1925@2 NA|NA|NA G PTS HPr component phosphorylation site LPKNPDNH_00399 702459.BBPR_1734 4.4e-200 703.7 Bifidobacteriales ko:K02529 ko00000,ko03000 Bacteria 2GJRG@201174,4CZ05@85004,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor LPKNPDNH_00400 398513.BBNG_01371 6.3e-213 746.5 Bifidobacteriales holB GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GJ8C@201174,4CZ4Y@85004,COG0470@1,COG0470@2 NA|NA|NA L DNA polymerase III LPKNPDNH_00401 398513.BBNG_01370 1.3e-118 432.6 Bifidobacteriales tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNTI@201174,4CYQ8@85004,COG0125@1,COG0125@2 NA|NA|NA F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis LPKNPDNH_00402 702459.BBPR_1738 0.0 1810.8 Bifidobacteriales topA GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097 5.99.1.2 ko:K03168 ko00000,ko01000,ko03032,ko03400 Bacteria 2GJU7@201174,4CZ85@85004,COG0550@1,COG0550@2,COG1754@1,COG1754@2 NA|NA|NA L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone LPKNPDNH_00403 702459.BBPR_1739 6.4e-183 646.7 Bifidobacteriales 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 2HIXE@201174,4CYS6@85004,COG0671@1,COG0671@2 NA|NA|NA I PAP2 superfamily LPKNPDNH_00404 702459.BBPR_1740 0.0 2455.6 Bifidobacteriales vpr GO:0005575,GO:0005576 ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Bacteria 2GK3D@201174,4CZV6@85004,COG1196@1,COG1196@2,COG1404@1,COG1404@2 NA|NA|NA M PA domain LPKNPDNH_00405 702459.BBPR_1741 3e-122 444.9 Bifidobacteriales yplQ ko:K11068 ko00000,ko02042 Bacteria 2HRAC@201174,4D0D6@85004,COG1272@1,COG1272@2 NA|NA|NA S Haemolysin-III related LPKNPDNH_00406 398513.BBNG_01365 4.6e-232 810.1 Bifidobacteriales glf GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0071554,GO:0071766,GO:0071840,GO:0071944,GO:0097159,GO:1901265,GO:1901363 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 iNJ661.Rv3809c Bacteria 2GK2Z@201174,4CZ2W@85004,COG0562@1,COG0562@2 NA|NA|NA M UDP-galactopyranose mutase LPKNPDNH_00407 398513.BBNG_01364 0.0 1252.3 Bifidobacteriales mrcB 2.4.1.129,3.4.16.4 ko:K05365,ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 2GK21@201174,4CZQZ@85004,COG0744@1,COG0744@2 NA|NA|NA M Transglycosylase LPKNPDNH_00408 398513.BBNG_01363 0.0 1268.8 Bifidobacteriales leuA GO:0000287,GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0030145,GO:0030955,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0046912,GO:0046914,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GISX@201174,4CZYW@85004,COG0119@1,COG0119@2 NA|NA|NA E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) LPKNPDNH_00409 398513.BBNG_01362 3.9e-278 963.4 Bifidobacteriales Bacteria 2GNKK@201174,4CZMC@85004,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase LPKNPDNH_00410 762211.BSTEL_2175 4.3e-14 83.6 Bifidobacteriales pbpB 2.7.11.1,3.4.16.4 ko:K03587,ko:K08384,ko:K08724,ko:K08884,ko:K12132 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01001,ko01011,ko03036 Bacteria 2IAHD@201174,4D094@85004,COG2815@1,COG2815@2 NA|NA|NA S PASTA domain LPKNPDNH_00411 702459.BBPR_1747 1.2e-288 998.8 Bifidobacteriales pbpB 2.7.11.1,3.4.16.4 ko:K03587,ko:K08384,ko:K08724,ko:K08884,ko:K12132 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01001,ko01011,ko03036 Bacteria 2IAHD@201174,4D094@85004,COG2815@1,COG2815@2 NA|NA|NA S PASTA domain LPKNPDNH_00412 398513.BBNG_01359 1.7e-116 425.2 Bifidobacteriales Bacteria 2C7PT@1,2GM64@201174,2ZXN2@2,4CYPY@85004 NA|NA|NA LPKNPDNH_00413 398513.BBNG_01358 1.1e-211 742.3 Bifidobacteriales asd GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0030312,GO:0036094,GO:0040007,GO:0043891,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071944,GO:0097159,GO:1901265,GO:1901363 1.2.1.11,1.2.1.12 ko:K00133,ko:K00134 ko00010,ko00260,ko00261,ko00270,ko00300,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04066,ko05010,map00010,map00260,map00261,map00270,map00300,map00710,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04066,map05010 M00001,M00002,M00003,M00016,M00017,M00018,M00033,M00165,M00166,M00308,M00525,M00526,M00527,M00552 R01061,R02291 RC00149,RC00684 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 2GJJ8@201174,4CZPY@85004,COG0136@1,COG0136@2 NA|NA|NA E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate LPKNPDNH_00415 702459.BBPR_1750 2.1e-97 361.7 Bifidobacteriales askB 1.1.1.3,2.7.2.4 ko:K00928,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN0G@201174,4D00P@85004,COG0527@1,COG0527@2 NA|NA|NA E ACT domain LPKNPDNH_00416 398513.BBNG_01357 1.8e-136 491.9 Bifidobacteriales ask GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3,2.7.2.4 ko:K00928,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN0G@201174,4CYSD@85004,COG0527@1,COG0527@2 NA|NA|NA E Amino acid kinase family LPKNPDNH_00417 398513.BBNG_01356 6.7e-110 403.3 Bifidobacteriales recR GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 2GJY0@201174,4CZRI@85004,COG0353@1,COG0353@2 NA|NA|NA L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO LPKNPDNH_00418 398513.BBNG_01355 0.0 1518.1 Bifidobacteriales dnaX GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0042575,GO:0042802,GO:0043170,GO:0043846,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050790,GO:0061695,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GJKA@201174,4CZMY@85004,COG2812@1,COG2812@2 NA|NA|NA L DNA polymerase III subunit gamma tau LPKNPDNH_00419 398513.BBNG_01354 3.2e-214 750.7 Bifidobacteriales dagK GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 R02240 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2GK3P@201174,4CZ1S@85004,COG1597@1,COG1597@2 NA|NA|NA I Diacylglycerol kinase catalytic domain protein LPKNPDNH_00420 398513.BBNG_01353 2e-56 224.9 Bifidobacteriales Bacteria 2DRBM@1,2HZRZ@201174,33B4F@2,4D1G6@85004 NA|NA|NA S TIGRFAM helicase secretion neighborhood TadE-like protein LPKNPDNH_00421 702459.BBPR_1758 1.9e-41 174.9 Bifidobacteriales Bacteria 2EHCF@1,2GR72@201174,33B4A@2,4D1FR@85004 NA|NA|NA S Protein of unknown function (DUF4244) LPKNPDNH_00422 398513.BBNG_01350 3.2e-15 86.7 Bifidobacteriales gspF ko:K12510,ko:K12511 ko00000,ko02044 Bacteria 2I2FP@201174,4D16W@85004,COG2064@1,COG2064@2 NA|NA|NA NU Type II secretion system (T2SS), protein F LPKNPDNH_00423 398513.BBNG_01350 1.4e-14 85.5 Bifidobacteriales gspF ko:K12510,ko:K12511 ko00000,ko02044 Bacteria 2I2FP@201174,4D16W@85004,COG2064@1,COG2064@2 NA|NA|NA NU Type II secretion system (T2SS), protein F LPKNPDNH_00424 398513.BBNG_01348 7.4e-121 439.9 Bifidobacteriales ko:K12510 ko00000,ko02044 Bacteria 2GRXU@201174,4D1A3@85004,COG4965@1,COG4965@2 NA|NA|NA U Type ii secretion system LPKNPDNH_00425 702459.BBPR_1761 3.4e-191 674.1 Bifidobacteriales cpaF ko:K02283 ko00000,ko02035,ko02044 Bacteria 2GKKJ@201174,4CZF2@85004,COG4962@1,COG4962@2 NA|NA|NA U Type II IV secretion system protein LPKNPDNH_00426 702459.BBPR_1762 7.5e-152 543.1 Bifidobacteriales cpaE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 ko:K04562 ko00000,ko02035 Bacteria 2HZIH@201174,4D0JG@85004,COG0455@1,COG0455@2 NA|NA|NA D bacterial-type flagellum organization LPKNPDNH_00428 398513.BBNG_01345 0.0 1478.4 Bifidobacteriales ppk 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 2GJ0B@201174,4CYXH@85004,COG0855@1,COG0855@2 NA|NA|NA P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) LPKNPDNH_00429 398513.BBNG_01344 5.1e-220 770.0 Bifidobacteriales mutT 3.6.1.13,3.6.1.55 ko:K01515,ko:K03574,ko:K08296 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000,ko03400 Bacteria 2GNRV@201174,4CZ90@85004,COG0494@1,COG0494@2,COG2062@1,COG2062@2 NA|NA|NA LT Phosphoglycerate mutase family LPKNPDNH_00430 398513.BBNG_01343 3.3e-90 338.2 Bifidobacteriales Bacteria 28MMU@1,2HAD5@201174,2ZAXG@2,4CZ1Q@85004 NA|NA|NA LPKNPDNH_00431 702459.BBPR_1766 2.1e-42 177.9 Bifidobacteriales cbiM GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K02007 ko02010,map02010 M00245,M00246 ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 Bacteria 2GK2U@201174,4CZXC@85004,COG0310@1,COG0310@2 NA|NA|NA P PDGLE domain LPKNPDNH_00432 398513.BBNG_01342 2.2e-57 228.0 Bifidobacteriales ureD ko:K03190 ko00000 Bacteria 2HZI9@201174,4D0IT@85004,COG0829@1,COG0829@2 NA|NA|NA O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter LPKNPDNH_00433 702459.BBPR_1768 2.5e-208 731.1 Bifidobacteriales Bacteria 2GMQQ@201174,4CZRJ@85004,COG1216@1,COG1216@2 NA|NA|NA S Glycosyltransferase, group 2 family protein LPKNPDNH_00434 398513.BBNG_01340 5.2e-262 909.8 Bifidobacteriales Bacteria 2DGST@1,2H2BZ@201174,2ZX5Y@2,4D1Y0@85004 NA|NA|NA LPKNPDNH_00436 398513.BBNG_01338 8.7e-27 125.6 Bifidobacteriales thiS 2.8.1.10 ko:K03149,ko:K03154 ko00730,ko01100,ko04122,map00730,map01100,map04122 R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 Bacteria 2GSKM@201174,4D1GS@85004,COG2104@1,COG2104@2 NA|NA|NA H ThiS family LPKNPDNH_00437 398513.BBNG_01337 1.9e-164 585.1 Bifidobacteriales thiG GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 iECABU_c1320.ECABU_c45060,iECO26_1355.ECO26_5099,ic_1306.c4947 Bacteria 2GM62@201174,4CZ4A@85004,COG2022@1,COG2022@2 NA|NA|NA H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S LPKNPDNH_00438 702459.BBPR_1772 0.0 1131.3 Bifidobacteriales Bacteria 2ANBU@1,2IAHJ@201174,31DA7@2,4CYW4@85004 NA|NA|NA S Psort location Cytoplasmic, score 8.87 LPKNPDNH_00439 398513.BBNG_01334 0.0 1308.5 Bifidobacteriales 2.1.1.107,2.1.1.294,2.7.1.181,2.7.11.1 ko:K02496,ko:K05802,ko:K08884,ko:K18827 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03194,R10657,R10658 RC00002,RC00003,RC00078,RC00871,RC03220 ko00000,ko00001,ko00002,ko01000,ko01001,ko01005,ko02000 1.A.23.1.1 Bacteria 2I2HI@201174,4CYVN@85004,COG2959@1,COG2959@2 NA|NA|NA H Protein of unknown function (DUF4012) LPKNPDNH_00440 398513.BBNG_01333 1.1e-246 859.0 Bifidobacteriales Bacteria 2GMGJ@201174,4CZBN@85004,COG0577@1,COG0577@2 NA|NA|NA V ABC transporter permease LPKNPDNH_00441 702459.BBPR_1776 1.1e-181 642.9 Bifidobacteriales ko:K02003,ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GNFW@201174,4CZAW@85004,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter LPKNPDNH_00442 398513.BBNG_01331 2.1e-137 495.0 Bifidobacteriales ko:K02030,ko:K06950 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 2GNQR@201174,4CYT9@85004,COG2206@1,COG2206@2 NA|NA|NA T HD domain LPKNPDNH_00443 398513.BBNG_01330 3.3e-166 590.9 Bifidobacteriales Bacteria 2IBFV@201174,4CYX2@85004,COG0121@1,COG0121@2 NA|NA|NA S Glutamine amidotransferase domain LPKNPDNH_00444 702459.BBPR_1780 0.0 1510.4 Bifidobacteriales kup GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 ko:K03549 ko00000,ko02000 2.A.72 Bacteria 2GMPQ@201174,4CZM3@85004,COG3158@1,COG3158@2 NA|NA|NA P Transport of potassium into the cell LPKNPDNH_00445 398513.BBNG_01327 1.3e-184 652.1 Bifidobacteriales tatD ko:K03424 ko00000,ko01000 Bacteria 2GMJJ@201174,4CYZI@85004,COG0084@1,COG0084@2 NA|NA|NA L TatD related DNase LPKNPDNH_00446 398513.BBNG_01326 4.2e-275 953.4 Bifidobacteriales xylR GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 5.3.1.12 ko:K01812,ko:K02529,ko:K16210 ko00040,ko01100,map00040,map01100 M00061,M00631 R01482,R01983 RC00376 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 2.A.2.5 Bacteria 2IAMT@201174,4CZNI@85004,COG1609@1,COG1609@2,COG2211@1,COG2211@2 NA|NA|NA G MFS/sugar transport protein LPKNPDNH_00448 702459.BBPR_1785 8.9e-87 326.2 Bifidobacteriales ko:K19505,ko:K21885 ko00000,ko03000 Bacteria 2HGTM@201174,4D2JT@85004,COG0640@1,COG0640@2 NA|NA|NA K Transcriptional regulator LPKNPDNH_00449 398513.BBNG_01322 0.0 1291.6 Bifidobacteriales metG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GK4S@201174,4CZ20@85004,COG0143@1,COG0143@2 NA|NA|NA J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation LPKNPDNH_00450 702459.BBPR_1788 3.6e-130 471.1 Bifidobacteriales Bacteria 2AU2N@1,2IJNI@201174,31JNZ@2,4D047@85004 NA|NA|NA LPKNPDNH_00451 398513.BBNG_01319 8.6e-59 233.0 Bifidobacteriales Bacteria 2B10P@1,2GS86@201174,31TDZ@2,4D1GZ@85004 NA|NA|NA LPKNPDNH_00452 398513.BBNG_01318 4.6e-172 610.5 Bifidobacteriales rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 ko:K07056 ko00000,ko01000,ko03009 Bacteria 2GJ9Q@201174,4CZ03@85004,COG0313@1,COG0313@2 NA|NA|NA H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA LPKNPDNH_00453 398513.BBNG_01317 2.7e-126 458.0 Bifidobacteriales dedA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03975 ko00000 Bacteria 2GKGR@201174,4CZ7Y@85004,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein LPKNPDNH_00455 702459.BBPR_1792 3.5e-134 484.2 Bifidobacteriales Bacteria 2GJNG@201174,4CYZV@85004,COG0637@1,COG0637@2 NA|NA|NA S HAD hydrolase, family IA, variant 3 LPKNPDNH_00456 702459.BBPR_1793 0.0 3330.4 Actinobacteria 3.2.1.18,3.2.1.51 ko:K01186,ko:K01206,ko:K20276 ko00511,ko00600,ko02024,ko04142,map00511,map00600,map02024,map04142 R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042,ko04147 GH29,GH33 Bacteria 2I0CJ@201174,COG1470@1,COG1470@2,COG2755@1,COG2755@2,COG4409@1,COG4409@2 NA|NA|NA G BNR Asp-box repeat LPKNPDNH_00457 398513.BBNG_01313 1.8e-230 805.1 Bifidobacteriales 3.2.1.18,3.2.1.51 ko:K01186,ko:K01206,ko:K20276 ko00511,ko00600,ko02024,ko04142,map00511,map00600,map02024,map04142 R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042,ko04147 GH29,GH33 Bacteria 2I0CJ@201174,4D02H@85004,COG1470@1,COG1470@2,COG4409@1,COG4409@2 NA|NA|NA G BNR repeat-like domain LPKNPDNH_00458 398513.BBNG_01313 1.1e-186 659.1 Bifidobacteriales 3.2.1.18,3.2.1.51 ko:K01186,ko:K01206,ko:K20276 ko00511,ko00600,ko02024,ko04142,map00511,map00600,map02024,map04142 R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042,ko04147 GH29,GH33 Bacteria 2I0CJ@201174,4D02H@85004,COG1470@1,COG1470@2,COG4409@1,COG4409@2 NA|NA|NA G BNR repeat-like domain LPKNPDNH_00459 702459.BBPR_1795 2.6e-86 324.7 Bifidobacteriales hspR ko:K13640 ko00000,ko03000 Bacteria 2IQJ4@201174,4D0Q7@85004,COG0789@1,COG0789@2 NA|NA|NA K transcriptional regulator, MerR family LPKNPDNH_00460 398513.BBNG_01311 7.1e-173 613.2 Bifidobacteriales dnaJ1 ko:K03686,ko:K05516 ko00000,ko03029,ko03036,ko03110 Bacteria 2GJKK@201174,4CZ68@85004,COG0484@1,COG0484@2 NA|NA|NA O DnaJ molecular chaperone homology domain LPKNPDNH_00462 702459.BBPR_1797 2.8e-59 235.3 Bifidobacteriales grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009628,GO:0009986,GO:0009987,GO:0009991,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030246,GO:0030247,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071496,GO:0071840,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 ko:K02652,ko:K03687 ko00000,ko02035,ko02044,ko03029,ko03110 3.A.15.2 Bacteria 2GP4F@201174,4CZJ6@85004,COG0576@1,COG0576@2 NA|NA|NA O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ LPKNPDNH_00463 398513.BBNG_01309 0.0 1123.6 Bifidobacteriales dnaK GO:0000302,GO:0000303,GO:0000305,GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016310,GO:0019222,GO:0019538,GO:0019899,GO:0030112,GO:0030162,GO:0030312,GO:0030313,GO:0031323,GO:0031325,GO:0031975,GO:0031982,GO:0032268,GO:0032270,GO:0033554,GO:0034599,GO:0034614,GO:0035375,GO:0036211,GO:0040007,GO:0042221,GO:0042603,GO:0043170,GO:0043226,GO:0043227,GO:0043230,GO:0043388,GO:0043412,GO:0044044,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046677,GO:0046688,GO:0046777,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051099,GO:0051101,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070613,GO:0070887,GO:0071450,GO:0071451,GO:0071704,GO:0071944,GO:0080090,GO:0097691,GO:1901564,GO:1901700,GO:1901701,GO:1903317,GO:1903319,GO:1903561,GO:2000677,GO:2000679 ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 Bacteria 2GJTY@201174,4CZDX@85004,COG0443@1,COG0443@2 NA|NA|NA O Heat shock 70 kDa protein LPKNPDNH_00464 702459.BBPR_1800 0.0 1346.3 Bifidobacteriales phoA 3.1.3.1,3.1.3.39 ko:K01077,ko:K04342 ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020 M00126 R02135,R02228,R04620 RC00017,RC00078 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Bacteria 2GM8A@201174,4CYZF@85004,COG1785@1,COG1785@2 NA|NA|NA P Alkaline phosphatase homologues LPKNPDNH_00465 702459.BBPR_1801 2.9e-190 671.0 Bifidobacteriales Bacteria 2GJBJ@201174,4CZ1Y@85004,COG1609@1,COG1609@2 NA|NA|NA K Psort location Cytoplasmic, score LPKNPDNH_00468 702459.BBPR_1804 1.8e-138 498.4 Bifidobacteriales Bacteria 2GNRS@201174,4CZD2@85004,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family LPKNPDNH_00469 398513.BBNG_01302 3e-69 267.7 Bifidobacteriales Bacteria 2B5DJ@1,2IRRR@201174,31Y80@2,4D1E6@85004 NA|NA|NA S Protein of unknown function (DUF4235) LPKNPDNH_00470 398513.BBNG_01301 1.2e-140 505.8 Bifidobacteriales nfrA 1.5.1.38,1.5.1.39 ko:K19285,ko:K19286 ko00740,ko01100,map00740,map01100 R05705,R05706 RC00126 ko00000,ko00001,ko01000 Bacteria 2I65Z@201174,4CZ5R@85004,COG0778@1,COG0778@2 NA|NA|NA C Nitroreductase family LPKNPDNH_00471 398513.BBNG_01300 1.1e-45 188.7 Bifidobacteriales Bacteria 2B78R@1,2IQGT@201174,320BB@2,4D178@85004 NA|NA|NA LPKNPDNH_00472 702459.BBPR_1809 4e-144 517.3 Bifidobacteriales cobB2 ko:K12410 ko00000,ko01000 Bacteria 2GJI3@201174,4CYUW@85004,COG0846@1,COG0846@2 NA|NA|NA K Sir2 family LPKNPDNH_00473 398513.BBNG_01742 1.3e-234 818.9 Bifidobacteriales tdcB GO:0003674,GO:0003824,GO:0003941,GO:0004793,GO:0004794,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006565,GO:0006566,GO:0006567,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016597,GO:0016829,GO:0016830,GO:0016832,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJAG@201174,4CYW0@85004,COG1171@1,COG1171@2 NA|NA|NA E Pyridoxal-phosphate dependent enzyme LPKNPDNH_00474 398513.BBNG_01743 1.1e-83 315.8 Bifidobacteriales tadA 3.5.4.1,3.5.4.33,3.8.1.5,6.3.4.19 ko:K01485,ko:K01563,ko:K04075,ko:K11991 ko00240,ko00330,ko00361,ko00625,ko01100,ko01120,map00240,map00330,map00361,map00625,map01100,map01120 R00974,R01411,R02922,R05284,R05367,R05368,R05369,R05370,R07669,R07670,R09597,R10223 RC00074,RC00477,RC00514,RC00809,RC01317,RC01340,RC01341,RC02013,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 Bacteria 2IM3Z@201174,4D0V0@85004,COG0590@1,COG0590@2 NA|NA|NA FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) LPKNPDNH_00475 398513.BBNG_01744 1.2e-145 522.3 Bifidobacteriales ypfH GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0052689 ko:K06999 ko00000 Bacteria 2I5NR@201174,4CZJQ@85004,COG0400@1,COG0400@2 NA|NA|NA S Phospholipase/Carboxylesterase LPKNPDNH_00476 702459.BBPR_1813 0.0 1187.6 Bifidobacteriales yjcE GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 ko:K03316 ko00000 2.A.36 Bacteria 2GIUT@201174,4CZC4@85004,COG0025@1,COG0025@2 NA|NA|NA P Sodium/hydrogen exchanger family LPKNPDNH_00477 398513.BBNG_01746 5.3e-112 410.2 Bifidobacteriales dcd GO:0003674,GO:0003824,GO:0004170,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0015949,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0033973,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 iPC815.YPO1525 Bacteria 2GKQQ@201174,4CZEB@85004,COG0717@1,COG0717@2 NA|NA|NA F Belongs to the dCTP deaminase family LPKNPDNH_00478 398513.BBNG_01747 0.0 1516.9 Bifidobacteriales 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 Bacteria 2GJJ1@201174,4CZJB@85004,COG3345@1,COG3345@2 NA|NA|NA G Glycosyl hydrolase family 36 N-terminal domain LPKNPDNH_00479 398513.BBNG_01748 0.0 1824.3 Bifidobacteriales pacL2 3.6.3.8 ko:K01537 ko00000,ko01000 3.A.3.2 Bacteria 2GJJC@201174,4CZ1I@85004,COG0474@1,COG0474@2 NA|NA|NA P Cation transporter/ATPase, N-terminus LPKNPDNH_00481 398513.BBNG_01751 9.9e-175 619.4 Bifidobacteriales rlmB GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 ko00000,ko01000,ko03009 Bacteria 2GJMR@201174,4CZB1@85004,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family LPKNPDNH_00482 398513.BBNG_01752 1e-270 938.7 Bifidobacteriales Bacteria 2I2F0@201174,4CZ2E@85004,COG0515@1,COG0515@2 NA|NA|NA KLT Domain of unknown function (DUF4032) LPKNPDNH_00483 702459.BBPR_1819 5.4e-153 547.0 Bifidobacteriales Bacteria 2EUBW@1,2ICS5@201174,33MU8@2,4D08R@85004 NA|NA|NA LPKNPDNH_00484 702459.BBPR_1820 4.5e-180 637.1 Bifidobacteriales 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria 2GNWT@201174,4CZMM@85004,COG3764@1,COG3764@2 NA|NA|NA M Sortase family LPKNPDNH_00485 547043.BIFPSEUDO_03204 1.4e-250 872.1 Bifidobacteriales Bacteria 2H1EY@201174,4D00Q@85004,COG4932@1,COG4932@2 NA|NA|NA M LPXTG-motif cell wall anchor domain protein LPKNPDNH_00486 326426.Bbr_1889 0.0 1983.8 Bifidobacteriales Bacteria 2CBRJ@1,2GKSC@201174,2Z7W0@2,4CZAS@85004 NA|NA|NA S LPXTG-motif cell wall anchor domain protein LPKNPDNH_00487 398513.BBNG_01756 0.0 2584.3 Bifidobacteriales Bacteria 2CBRJ@1,2GKSC@201174,2Z7W0@2,4CZAS@85004 NA|NA|NA S LPXTG-motif cell wall anchor domain protein LPKNPDNH_00488 702459.BBPR_1823 2.3e-101 374.8 Bifidobacteriales Bacteria 2H4CW@201174,4D25Y@85004,COG2826@1,COG2826@2 NA|NA|NA L Helix-turn-helix domain LPKNPDNH_00489 702459.BBPR_1824 1.6e-210 738.4 Bifidobacteriales ugpC ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 ko00000,ko00001,ko00002,ko02000 3.A.1.1 Bacteria 2GJCM@201174,4CYU6@85004,COG3842@1,COG3842@2 NA|NA|NA E Belongs to the ABC transporter superfamily LPKNPDNH_00490 398513.BBNG_01759 1.3e-173 615.5 Bifidobacteriales Bacteria 2ICPH@201174,4CZJ7@85004,COG5340@1,COG5340@2 NA|NA|NA K Psort location Cytoplasmic, score LPKNPDNH_00491 702459.BBPR_1826 0.0 1380.9 Bifidobacteriales Bacteria 2GIV0@201174,4CYQG@85004,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase LPKNPDNH_00492 702459.BBPR_1827 7.1e-150 537.0 Bifidobacteriales Bacteria 2GN3N@201174,4CZBD@85004,COG1651@1,COG1651@2 NA|NA|NA O Thioredoxin LPKNPDNH_00494 702459.BBPR_1828 1.2e-211 742.7 Bifidobacteriales Bacteria 2H4RU@201174,4CYY0@85004,COG3583@1,COG3583@2 NA|NA|NA S G5 LPKNPDNH_00495 398513.BBNG_01763 4.8e-171 607.1 Bifidobacteriales ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182,2.1.1.184 ko:K00561,ko:K02528 R10716 RC00003,RC03257 br01600,ko00000,ko01000,ko01504,ko03009 Bacteria 2GKBT@201174,4CYS9@85004,COG0030@1,COG0030@2 NA|NA|NA J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits LPKNPDNH_00496 398513.BBNG_01764 2.1e-167 595.1 Bifidobacteriales ispE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.1.1.182,2.7.1.148 ko:K00919,ko:K02528,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096,M00582 R05634,R10716 RC00002,RC00003,RC01439,RC03257 ko00000,ko00001,ko00002,ko01000,ko02000,ko03009 3.A.1.29 iEC55989_1330.EC55989_1304,iLJ478.TM1383,iYO844.BSU00460 Bacteria 2GKXD@201174,4CZMW@85004,COG1947@1,COG1947@2 NA|NA|NA F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol LPKNPDNH_00497 398513.BBNG_01765 6.7e-113 413.3 Bifidobacteriales Bacteria 2E1BJ@1,2IKG0@201174,32WRF@2,4D0S1@85004 NA|NA|NA S LytR cell envelope-related transcriptional attenuator LPKNPDNH_00498 702459.BBPR_1832 2.8e-279 967.2 Bifidobacteriales cca 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 Bacteria 2GMT1@201174,4CYUH@85004,COG0617@1,COG0617@2 NA|NA|NA J Probable RNA and SrmB- binding site of polymerase A LPKNPDNH_00499 398513.BBNG_01767 5.2e-124 450.3 Bifidobacteriales deoC 3.6.1.13,3.6.1.17,3.6.1.55,3.6.1.61 ko:K01515,ko:K01518,ko:K03574,ko:K18445 ko00230,ko00240,map00230,map00240 R00184,R00969,R01054,R01232,R02805 RC00002 ko00000,ko00001,ko01000,ko03400 Bacteria 2GWEB@201174,4CZAV@85004,COG0494@1,COG0494@2 NA|NA|NA L Belongs to the Nudix hydrolase family LPKNPDNH_00500 702459.BBPR_1834 0.0 1362.4 Bifidobacteriales Bacteria 2I2GZ@201174,4D2V9@85004,COG1361@1,COG1361@2 NA|NA|NA M Conserved repeat domain LPKNPDNH_00501 398513.BBNG_01769 0.0 2552.3 Bifidobacteriales murJ ko:K03980 ko00000,ko01011,ko02000 2.A.66.4 Bacteria 2GKN0@201174,4CZ8M@85004,COG0515@1,COG0515@2,COG0728@1,COG0728@2 NA|NA|NA KLT MviN-like protein LPKNPDNH_00502 398513.BBNG_01770 2.6e-203 714.5 Bifidobacteriales trxB GO:0000166,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9,4.3.1.9 ko:K00384,ko:K22345 ko00030,ko00450,map00030,map00450 R01544,R02016,R03596,R09372 RC00013,RC00544,RC02518,RC02873 ko00000,ko00001,ko01000 iPC815.YPO1374 Bacteria 2GKD2@201174,4CYU9@85004,COG0492@1,COG0492@2 NA|NA|NA C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family LPKNPDNH_00503 702459.BBPR_1837 1.2e-242 845.5 Bifidobacteriales parB GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944 ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 2GNRN@201174,4CYUE@85004,COG1475@1,COG1475@2 NA|NA|NA K Belongs to the ParB family LPKNPDNH_00504 702459.BBPR_1838 8.5e-179 632.9 Bifidobacteriales parA ko:K03496 ko00000,ko03036,ko04812 Bacteria 2GMU7@201174,4CZ2D@85004,COG1192@1,COG1192@2 NA|NA|NA D CobQ CobB MinD ParA nucleotide binding domain protein LPKNPDNH_00505 398513.BBNG_01773 1.3e-125 455.7 Bifidobacteriales rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 ko00000,ko01000,ko03009,ko03036 Bacteria 2GM9Z@201174,4CZ29@85004,COG0357@1,COG0357@2 NA|NA|NA J Specifically methylates the N7 position of a guanine in 16S rRNA LPKNPDNH_00506 702459.BBPR_1840 8.6e-93 346.3 Bifidobacteriales jag ko:K06346,ko:K09749 ko00000 Bacteria 2GPZK@201174,4CYQQ@85004,COG1847@1,COG1847@2 NA|NA|NA S Putative single-stranded nucleic acids-binding domain LPKNPDNH_00507 398513.BBNG_01775 1e-171 609.4 Bifidobacteriales yidC ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 2GJBU@201174,4CYZ2@85004,COG0706@1,COG0706@2 NA|NA|NA U Membrane protein insertase, YidC Oxa1 family LPKNPDNH_00508 398513.BBNG_01778 4.5e-14 82.8 Bifidobacteriales rpmH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02914 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GQFY@201174,4D1EF@85004,COG0230@1,COG0230@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL34 family LPKNPDNH_00509 398513.BBNG_01779 4.1e-300 1036.6 Bifidobacteriales dnaA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 Bacteria 2GJKI@201174,4CZDW@85004,COG0593@1,COG0593@2 NA|NA|NA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids LPKNPDNH_00510 702459.BBPR_0002 6e-205 719.9 Bifidobacteriales dnaN GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GJK3@201174,4CZTV@85004,COG0592@1,COG0592@2 NA|NA|NA L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria LPKNPDNH_00511 702459.BBPR_0003 2e-239 834.7 Bifidobacteriales recF GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 ko:K03629,ko:K07459 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 2GJCS@201174,4CZQT@85004,COG1195@1,COG1195@2 NA|NA|NA L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP LPKNPDNH_00512 398513.BBNG_01782 2e-87 328.6 Bifidobacteriales Bacteria 2GNQ4@201174,4D157@85004,COG5512@1,COG5512@2 NA|NA|NA S Protein of unknown function (DUF721) LPKNPDNH_00513 702459.BBPR_0005 0.0 1416.0 Bifidobacteriales gyrB GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02470 ko00000,ko01000,ko03032,ko03400 Bacteria 2GKGP@201174,4CZ47@85004,COG0187@1,COG0187@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner LPKNPDNH_00514 702459.BBPR_0006 0.0 1696.4 Bifidobacteriales gyrA GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02469 ko00000,ko01000,ko03032,ko03400 Bacteria 2GJ2Q@201174,4CYRP@85004,COG0188@1,COG0188@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner LPKNPDNH_00515 398513.BBNG_01786 4.6e-73 280.8 Bifidobacteriales GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 Bacteria 2GKZP@201174,4D0XB@85004,COG3266@1,COG3266@2 NA|NA|NA S Transmembrane domain of unknown function (DUF3566) LPKNPDNH_00516 1437600.JDUI01000001_gene619 2.6e-15 87.8 Bifidobacteriales abfA1 3.2.1.55 ko:K01209 ko00520,map00520 R01762 ko00000,ko00001,ko01000 GH51 Bacteria 2GMAK@201174,4CYXS@85004,COG3534@1,COG3534@2 NA|NA|NA G arabinose metabolic process LPKNPDNH_00518 398513.BBNG_01788 4.6e-187 660.2 Bifidobacteriales Bacteria 2GNEY@201174,4D05A@85004,COG3507@1,COG3507@2 NA|NA|NA G Glycosyl hydrolases family 43 LPKNPDNH_00519 702459.BBPR_0012 1.6e-187 662.1 Bifidobacteriales Bacteria 2GJV7@201174,4CZUG@85004,COG1609@1,COG1609@2 NA|NA|NA K Periplasmic binding protein domain LPKNPDNH_00520 702459.BBPR_0013 2.6e-227 794.3 Bifidobacteriales Bacteria 2GIVB@201174,4D077@85004,COG2267@1,COG2267@2 NA|NA|NA I Serine aminopeptidase, S33 LPKNPDNH_00521 1437610.BREU_1933 8.3e-09 65.9 Bifidobacteriales Bacteria 2GJV7@201174,4D04H@85004,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor LPKNPDNH_00523 398513.BBNG_01793 1.9e-24 119.4 Bifidobacteriales gdhA 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 R00248 RC00006,RC02799 ko00000,ko00001,ko01000 Bacteria 2GKXG@201174,4CYTN@85004,COG0334@1,COG0334@2 NA|NA|NA E Belongs to the Glu Leu Phe Val dehydrogenases family LPKNPDNH_00524 398513.BBNG_01793 2.3e-259 901.0 Bifidobacteriales gdhA 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 R00248 RC00006,RC02799 ko00000,ko00001,ko01000 Bacteria 2GKXG@201174,4CYTN@85004,COG0334@1,COG0334@2 NA|NA|NA E Belongs to the Glu Leu Phe Val dehydrogenases family LPKNPDNH_00525 398513.BBNG_01794 2.5e-124 451.4 Bifidobacteriales gntR ko:K19776 ko00000,ko03000 Bacteria 2GKBM@201174,4CYZS@85004,COG2186@1,COG2186@2 NA|NA|NA K FCD LPKNPDNH_00526 398513.BBNG_01795 2.5e-50 204.9 Bifidobacteriales mscL GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 ko:K03282 ko00000,ko02000 1.A.22.1 Bacteria 2IQDN@201174,4D13A@85004,COG1970@1,COG1970@2 NA|NA|NA M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell LPKNPDNH_00527 702459.BBPR_0025 0.0 2077.0 Bifidobacteriales 3.2.1.55 ko:K01209 ko00520,map00520 R01762 ko00000,ko00001,ko01000 GH51 Bacteria 2GMAK@201174,4CYXS@85004,COG2931@1,COG2931@2,COG3534@1,COG3534@2,COG4932@1,COG4932@2 NA|NA|NA G arabinose metabolic process LPKNPDNH_00530 702459.BBPR_0026 0.0 1559.3 Bifidobacteriales Bacteria 2HZCI@201174,4CZS1@85004,COG3525@1,COG3525@2 NA|NA|NA G Glycosyl hydrolase family 20, domain 2 LPKNPDNH_00531 702459.BBPR_0029 3.9e-190 670.6 Bifidobacteriales ko:K02529 ko00000,ko03000 Bacteria 2GJRG@201174,4CZ05@85004,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor LPKNPDNH_00532 702459.BBPR_0030 4.3e-77 293.9 Bifidobacteriales ulaC 2.7.1.194,2.7.1.197,2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02798,ko:K02821 ko00051,ko00053,ko01100,ko01120,ko02060,map00051,map00053,map01100,map01120,map02060 M00273,M00274,M00283,M00550 R02704,R03232,R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5,4.A.7.1 Bacteria 2I8CH@201174,4D0XI@85004,COG1762@1,COG1762@2 NA|NA|NA G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 LPKNPDNH_00533 702459.BBPR_0031 9.6e-40 169.1 Bifidobacteriales ulaC 2.7.1.194 ko:K02821,ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 Bacteria 2GUM3@201174,4D1AA@85004,COG3414@1,COG3414@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit LPKNPDNH_00534 398513.BBNG_01800 2.8e-261 907.5 Bifidobacteriales ulaA 2.7.1.194 ko:K02822,ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 Bacteria 2GMYV@201174,4D064@85004,COG3037@1,COG3037@2 NA|NA|NA S PTS system sugar-specific permease component LPKNPDNH_00535 398513.BBNG_01801 1.9e-135 488.4 Bifidobacteriales ko:K07043 ko00000 Bacteria 2GMP6@201174,4CZF9@85004,COG1451@1,COG1451@2 NA|NA|NA S Protein of unknown function DUF45 LPKNPDNH_00536 398513.BBNG_01802 1.9e-83 315.1 Bifidobacteriales dps GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 ko:K04047 ko00000,ko03036 Bacteria 2IFDP@201174,4CZV3@85004,COG0783@1,COG0783@2 NA|NA|NA P Belongs to the Dps family LPKNPDNH_00537 702459.BBPR_0035 1.3e-188 665.6 Bifidobacteriales yddG GO:0003333,GO:0003674,GO:0005215,GO:0005302,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015179,GO:0015192,GO:0015196,GO:0015238,GO:0015318,GO:0015711,GO:0015801,GO:0015807,GO:0015823,GO:0015827,GO:0015828,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 iBWG_1329.BWG_1294,iE2348C_1286.E2348C_1607,iECDH10B_1368.ECDH10B_1604,iECDH1ME8569_1439.ECDH1ME8569_1416,iECS88_1305.ECS88_1565,iEcDH1_1363.EcDH1_2175,iJO1366.b1473,iNRG857_1313.NRG857_07295,iSSON_1240.SSON_1651,iUMN146_1321.UM146_09675 Bacteria 2GM6M@201174,4CZPP@85004,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family LPKNPDNH_00538 398513.BBNG_01804 3.6e-241 840.5 Bifidobacteriales ytfL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03699 ko00000,ko02042 Bacteria 2GKN5@201174,4CZKA@85004,COG1253@1,COG1253@2 NA|NA|NA P Transporter associated domain LPKNPDNH_00539 398513.BBNG_01805 1.1e-95 355.9 Bifidobacteriales ko:K02529 ko00000,ko03000 Bacteria 2GM7M@201174,4D2RZ@85004,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor LPKNPDNH_00540 398513.BBNG_01806 6.9e-119 433.3 Bifidobacteriales cah GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008270,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944 4.2.1.1 ko:K01673 ko00910,map00910 R00132,R10092 RC02807 ko00000,ko00001,ko01000 Bacteria 2GT5H@201174,4D06V@85004,COG0288@1,COG0288@2 NA|NA|NA P Reversible hydration of carbon dioxide LPKNPDNH_00541 398513.BBNG_01807 2.9e-107 394.4 Bifidobacteriales ahpC 1.11.1.15 ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Bacteria 2GM74@201174,4CZXS@85004,COG0450@1,COG0450@2 NA|NA|NA O C-terminal domain of 1-Cys peroxiredoxin LPKNPDNH_00542 398513.BBNG_01808 0.0 1157.1 Bifidobacteriales trxB1 1.8.1.9 ko:K00384 ko00450,map00450 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 Bacteria 2GKD2@201174,4CZ6G@85004,COG0492@1,COG0492@2,COG3634@1,COG3634@2 NA|NA|NA C Thioredoxin domain LPKNPDNH_00543 398513.BBNG_01809 1.3e-309 1068.1 Bifidobacteriales 3.6.4.12 ko:K03655,ko:K10439,ko:K11708 ko02010,ko02030,ko03440,map02010,map02030,map03440 M00212,M00319 ko00000,ko00001,ko00002,ko01000,ko02000,ko03400 3.A.1.15,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 Bacteria 2I3IG@201174,4CZRW@85004,COG1414@1,COG1414@2,COG2865@1,COG2865@2 NA|NA|NA K Putative ATP-dependent DNA helicase recG C-terminal LPKNPDNH_00544 398513.BBNG_01810 4.3e-239 833.6 Bifidobacteriales yhjX ko:K08177 ko00000,ko02000 2.A.1.11 Bacteria 2I2ID@201174,4CZX9@85004,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily LPKNPDNH_00545 398513.BBNG_01811 0.0 1810.0 Bifidobacteriales ppc GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 iJN678.ppc Bacteria 2GKDB@201174,4CZS0@85004,COG2352@1,COG2352@2 NA|NA|NA H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle LPKNPDNH_00546 702459.BBPR_0043 0.0 1223.8 Bifidobacteriales yjjP Bacteria 2HZ8C@201174,4CYR2@85004,COG2966@1,COG2966@2,COG3610@1,COG3610@2 NA|NA|NA S Threonine/Serine exporter, ThrE LPKNPDNH_00547 398513.BBNG_01814 1.4e-177 629.0 Bifidobacteriales Bacteria 2GJVW@201174,4CZQ4@85004,COG1574@1,COG1574@2 NA|NA|NA S Amidohydrolase family LPKNPDNH_00548 702459.BBPR_0045 1.8e-195 688.3 Bifidobacteriales gmk 1.1.1.23,2.7.4.8 ko:K00013,ko:K00942 ko00230,ko00340,ko01100,ko01110,ko01230,map00230,map00340,map01100,map01110,map01230 M00026,M00050 R00332,R01158,R01163,R02090,R03012 RC00002,RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN40@201174,4CZPZ@85004,COG2852@1,COG2852@2 NA|NA|NA S Protein conserved in bacteria LPKNPDNH_00549 398513.BBNG_01816 3.2e-203 714.1 Bifidobacteriales trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GJ9A@201174,4CYXM@85004,COG0180@1,COG0180@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family LPKNPDNH_00550 398513.BBNG_01817 1e-47 196.1 Bifidobacteriales Bacteria 2EGRW@1,2HZNH@201174,32FNP@2,4D120@85004 NA|NA|NA S Protein of unknown function (DUF3073) LPKNPDNH_00551 702459.BBPR_0049 2.7e-111 407.9 Bacteria Bacteria COG3290@1,COG3290@2 NA|NA|NA T protein histidine kinase activity LPKNPDNH_00552 702459.BBPR_0050 1e-203 715.7 Bifidobacteriales rfbB GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv3464 Bacteria 2GNDU@201174,4CZZY@85004,COG1088@1,COG1088@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily LPKNPDNH_00553 398513.BBNG_01822 1.1e-24 118.6 Bifidobacteriales Bacteria 2H65A@201174,4D2BH@85004,COG1835@1,COG1835@2 NA|NA|NA I transferase activity, transferring acyl groups other than amino-acyl groups LPKNPDNH_00554 702459.BBPR_0052 0.0 1149.4 Bifidobacteriales lytC 2.1.1.197,3.2.1.17,3.2.1.96 ko:K01185,ko:K01227,ko:K02169 ko00511,ko00780,ko01100,map00511,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 Bacteria 2I2GQ@201174,4D08Z@85004,COG2273@1,COG2273@2,COG3533@1,COG3533@2,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 LPKNPDNH_00555 216816.GS08_09745 6.5e-167 595.1 Bifidobacteriales rfbJ Bacteria 2I2GR@201174,4CZTN@85004,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase family 2 LPKNPDNH_00556 78344.BIGA_0320 2.8e-72 278.1 Bifidobacteriales GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 ko:K07485 ko00000 Bacteria 2GJK7@201174,4D0ME@85004,COG3464@1,COG3464@2 NA|NA|NA L Transposase LPKNPDNH_00557 216816.GS08_09755 1.3e-207 728.8 Bifidobacteriales Bacteria 2IER7@201174,4D0M4@85004,COG3274@1,COG3274@2 NA|NA|NA S Acyltransferase family LPKNPDNH_00558 216816.GS08_09760 4e-298 1030.0 Bifidobacteriales Bacteria 2DGTK@1,2I42E@201174,2ZX8T@2,4D2WB@85004 NA|NA|NA LPKNPDNH_00559 216816.GS08_09765 0.0 2071.6 Bifidobacteriales wbbM Bacteria 2I2GT@201174,4D2V5@85004,COG0463@1,COG0463@2,COG1442@1,COG1442@2 NA|NA|NA M Glycosyl transferase family 8 LPKNPDNH_00560 216816.GS08_09770 2.6e-174 617.8 Bifidobacteriales ppm1 GO:0000030,GO:0003674,GO:0003824,GO:0004582,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0070085,GO:0071704,GO:0071944,GO:0075136,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 ko:K03820 ko00000,ko01000 GT2 iNJ661.Rv2051c Bacteria 2I9NQ@201174,4D0NJ@85004,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase, family 2 LPKNPDNH_00561 216816.GS08_09775 0.0 1332.8 Bifidobacteriales Bacteria 2I5AE@201174,4D2XE@85004,COG2247@1,COG2247@2 NA|NA|NA M Belongs to the glycosyl hydrolase 43 family LPKNPDNH_00562 326426.Bbr_0453 9.8e-127 459.5 Bifidobacteriales ko:K02315 ko00000,ko03032 Bacteria 2IA1S@201174,4CZFE@85004,COG1484@1,COG1484@2 NA|NA|NA L IstB-like ATP binding protein LPKNPDNH_00563 1437600.JDUI01000008_gene1350 8.6e-244 849.4 Bifidobacteriales Bacteria 2GM4J@201174,4CZXZ@85004,COG4584@1,COG4584@2 NA|NA|NA L Transposase LPKNPDNH_00564 1680.BADO_1518 2.1e-142 512.3 Actinobacteria Bacteria 2IG1A@201174,COG2247@1,COG2247@2 NA|NA|NA M Putative cell wall binding repeat 2 LPKNPDNH_00565 1680.BADO_1519 5.6e-121 440.7 Actinobacteria Bacteria 2GJ38@201174,COG2247@1,COG2247@2,COG2356@1,COG2356@2 NA|NA|NA L Protein of unknown function (DUF1524) LPKNPDNH_00566 78346.BRUM_1821 0.0 2307.7 Bifidobacteriales 2.1.1.72,3.1.4.46,3.2.1.1 ko:K00571,ko:K01126,ko:K01176 ko00500,ko00564,ko01100,ko04973,map00500,map00564,map01100,map04973 R01030,R01470,R02108,R02112,R11262 RC00017,RC00425 ko00000,ko00001,ko01000,ko02048 GH13 Bacteria 2I42D@201174,4D07U@85004,COG1404@1,COG1404@2,COG3209@1,COG3209@2,COG3291@1,COG3291@2,COG3757@1,COG3757@2,COG4886@1,COG4886@2 NA|NA|NA M hydrolase, family 25 LPKNPDNH_00567 216816.GS08_09790 1.8e-240 838.2 Bifidobacteriales rgpD 3.6.3.38 ko:K01990,ko:K09689,ko:K09691 ko02010,map02010 M00249,M00250,M00254 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.101,3.A.1.103 Bacteria 2GIVF@201174,4CZ1B@85004,COG1134@1,COG1134@2 NA|NA|NA GM ABC transporter, ATP-binding protein LPKNPDNH_00568 216816.GS08_09795 2.5e-139 501.5 Bifidobacteriales rgpC ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GP5K@201174,4CZ73@85004,COG1682@1,COG1682@2 NA|NA|NA U Transport permease protein LPKNPDNH_00569 78346.BRUM_1827 0.0 1201.4 Bifidobacteriales wbbM Bacteria 2I2GU@201174,4D0KN@85004,COG1442@1,COG1442@2 NA|NA|NA M Glycosyl transferase family 8 LPKNPDNH_00570 78346.BRUM_1493 3.2e-215 754.2 Bifidobacteriales 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJQB@201174,4CZ1N@85004,COG1004@1,COG1004@2 NA|NA|NA M UDP binding domain LPKNPDNH_00571 1680.BADO_1525 4.4e-15 86.7 Bifidobacteriales XK27_08315 Bacteria 2HVID@201174,4CZ6J@85004,COG1368@1,COG1368@2 NA|NA|NA M Psort location CytoplasmicMembrane, score 9.26 LPKNPDNH_00572 78346.BRUM_1693 1.2e-153 549.7 Bifidobacteriales Bacteria 2GS79@201174,4D0H8@85004,COG3547@1,COG3547@2 NA|NA|NA K Transposase IS116 IS110 IS902 LPKNPDNH_00573 1437600.JDUI01000007_gene734 7.3e-119 433.7 Bifidobacteriales tnp7109-21 Bacteria 2GKDY@201174,4CZUB@85004,COG2801@1,COG2801@2 NA|NA|NA L Integrase core domain LPKNPDNH_00574 398513.BBNG_00722 2.6e-43 181.4 Bifidobacteriales ko:K07483 ko00000 Bacteria 2IQ8F@201174,4D1BJ@85004,COG2963@1,COG2963@2 NA|NA|NA L Transposase LPKNPDNH_00575 1499680.CCFE01000030_gene3389 3.3e-09 67.4 Bacillus Bacteria 1UC29@1239,1ZNIM@1386,29SWS@1,30E30@2,4INIC@91061 NA|NA|NA LPKNPDNH_00577 158787.BSCA_0159 9.5e-45 186.8 Bifidobacteriales Bacteria 2GX1N@201174,4D2D5@85004,COG3293@1,COG3293@2 NA|NA|NA L Transposase DDE domain LPKNPDNH_00578 327277.JHAL01000001_gene1431 2.7e-156 558.5 Bifidobacteriales bglA 3.2.1.21 ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 Bacteria 2GJAF@201174,4CYPX@85004,COG2723@1,COG2723@2 NA|NA|NA G Glycosyl hydrolase family 1 LPKNPDNH_00579 78346.BRUM_0133 3.8e-194 684.1 Bifidobacteriales Bacteria 2GM8F@201174,4D023@85004,COG3328@1,COG3328@2 NA|NA|NA L Transposase, Mutator family LPKNPDNH_00580 78346.BRUM_0546 2.6e-227 794.3 Bifidobacteriales glf GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0071554,GO:0071766,GO:0071840,GO:0071944,GO:0097159,GO:1901265,GO:1901363 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 iNJ661.Rv3809c Bacteria 2GK2Z@201174,4CZ2W@85004,COG0562@1,COG0562@2 NA|NA|NA M UDP-galactopyranose mutase LPKNPDNH_00581 1437600.JDUI01000010_gene241 2.6e-43 182.2 Bifidobacteriales 3.6.1.13 ko:K01515 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000 Bacteria 2I5YQ@201174,4D1BK@85004,COG0494@1,COG0494@2 NA|NA|NA L NUDIX domain LPKNPDNH_00582 1437600.JDUI01000010_gene242 1.5e-101 377.1 Bifidobacteriales Bacteria 2A0Y7@1,2ICTN@201174,30P3F@2,4D0DG@85004 NA|NA|NA LPKNPDNH_00583 566552.BIFCAT_00308 4e-203 713.8 Bifidobacteriales rfbB GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv3464 Bacteria 2GNDU@201174,4CZZY@85004,COG1088@1,COG1088@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily LPKNPDNH_00584 326426.Bbr_0832 1.5e-215 755.4 Bifidobacteriales Bacteria 2HZ9S@201174,4CZ4Z@85004,COG2271@1,COG2271@2 NA|NA|NA G Transmembrane secretion effector LPKNPDNH_00585 216816.GS08_04235 2e-118 431.8 Bifidobacteriales Bacteria 2HZJX@201174,4D0QJ@85004,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family LPKNPDNH_00586 398513.BBNG_00004 3.5e-12 76.3 Bifidobacteriales Bacteria 29G83@1,2GQWW@201174,3035W@2,4D1G9@85004 NA|NA|NA LPKNPDNH_00587 398513.BBNG_00006 0.0 1239.6 Bifidobacteriales cysB 4.2.1.22 ko:K01697,ko:K18926 ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230 M00035,M00338,M00715 R00891,R01290,R04942 RC00056,RC00069,RC00256,RC00489,RC01246 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.1.3.30 Bacteria 2GIZX@201174,4CZWX@85004,COG0477@1,COG0517@1,COG0517@2,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily LPKNPDNH_00588 398513.BBNG_00007 1.1e-42 178.7 Bifidobacteriales tnp7109-21 Bacteria 2GVZP@201174,4D1IR@85004,COG2801@1,COG2801@2 NA|NA|NA L Integrase core domain LPKNPDNH_00589 398513.BBNG_00008 2.5e-52 211.1 Bifidobacteriales ko:K02315 ko00000,ko03032 Bacteria 2H714@201174,4CZRM@85004,COG1484@1,COG1484@2 NA|NA|NA L IstB-like ATP binding protein LPKNPDNH_00590 398513.BBNG_00010 8.7e-46 189.1 Bifidobacteriales GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 ko:K07485 ko00000 Bacteria 2GJK7@201174,4D0ME@85004,COG3464@1,COG3464@2 NA|NA|NA L Transposase LPKNPDNH_00591 398513.BBNG_00011 2e-73 281.6 Bifidobacteriales Bacteria 2IQBF@201174,4D10H@85004,COG3255@1,COG3255@2 NA|NA|NA I Sterol carrier protein LPKNPDNH_00592 398513.BBNG_00012 0.0 1661.7 Bifidobacteriales glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 R02111 ko00000,ko00001,ko01000 GT35 Bacteria 2GIVZ@201174,4CZ3V@85004,COG0058@1,COG0058@2 NA|NA|NA G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties LPKNPDNH_00593 398513.BBNG_00013 3.4e-35 153.7 Bifidobacteriales Bacteria 2BFAJ@1,2ISGB@201174,3293I@2,4D185@85004 NA|NA|NA LPKNPDNH_00594 702459.BBPR_0095 1.9e-144 518.5 Bifidobacteriales gluP 3.4.21.105 ko:K19225 ko00000,ko01000,ko01002 Bacteria 2GJYG@201174,4CZJ0@85004,COG0705@1,COG0705@2 NA|NA|NA S Rhomboid family LPKNPDNH_00595 398513.BBNG_00015 1.6e-88 332.4 Bifidobacteriales ko:K07497,ko:K09958 ko00000 Bacteria 2GKW1@201174,4CYXY@85004,COG2801@1,COG2801@2 NA|NA|NA L HTH-like domain LPKNPDNH_00596 702459.BBPR_0096 1.4e-256 891.7 Bifidobacteriales ko:K15257 ko00000,ko01000,ko03016 Bacteria 2HZAY@201174,4CZEU@85004,COG0742@1,COG0742@2 NA|NA|NA L ribosomal rna small subunit methyltransferase LPKNPDNH_00597 398513.BBNG_00017 2.6e-71 274.6 Bifidobacteriales crgA Bacteria 2E4NY@1,2GQPW@201174,32ZHR@2,4D0ZH@85004 NA|NA|NA D Involved in cell division LPKNPDNH_00598 702459.BBPR_0098 7.9e-143 513.1 Bifidobacteriales Bacteria 2GJ9Y@201174,4CZ1A@85004,COG3879@1,COG3879@2 NA|NA|NA S Bacterial protein of unknown function (DUF881) LPKNPDNH_00599 702459.BBPR_0099 1.8e-231 808.1 Bifidobacteriales srtA 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria 2GKT6@201174,4CYZ5@85004,COG3764@1,COG3764@2 NA|NA|NA M Sortase family LPKNPDNH_00600 398513.BBNG_00020 3.4e-120 437.6 Bifidobacteriales trpG GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 ko:K01664,ko:K13950 ko00790,map00790 R01716 RC00010,RC01418 ko00000,ko00001,ko01000 Bacteria 2GJUX@201174,4D09E@85004,COG0512@1,COG0512@2 NA|NA|NA EH para-aminobenzoate synthase glutamine amidotransferase component II LPKNPDNH_00601 398513.BBNG_00021 0.0 1231.5 Bifidobacteriales pknB 2.7.11.1 ko:K12132 ko00000,ko01000,ko01001 Bacteria 2GJ1J@201174,4CZFU@85004,COG0515@1,COG0515@2,COG2815@1,COG2815@2 NA|NA|NA KLT Protein tyrosine kinase LPKNPDNH_00602 398513.BBNG_00022 2e-183 648.3 Bifidobacteriales Bacteria 2GMPZ@201174,4CYUK@85004,COG0515@1,COG0515@2 NA|NA|NA T Protein tyrosine kinase LPKNPDNH_00603 398513.BBNG_00023 3.7e-263 913.7 Bifidobacteriales pbpA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K05364 ko00550,map00550 R04519 RC00005,RC00049 ko00000,ko00001,ko01011 Bacteria 2GJUQ@201174,4CYTI@85004,COG0768@1,COG0768@2 NA|NA|NA M penicillin-binding protein LPKNPDNH_00604 398513.BBNG_00024 2.8e-266 924.1 Bifidobacteriales rodA GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 ko:K03588,ko:K05364,ko:K05837 ko00550,ko04112,map00550,map04112 R04519 RC00005,RC00049 ko00000,ko00001,ko01011,ko02000,ko03036 2.A.103.1 Bacteria 2GJTI@201174,4CZ67@85004,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family LPKNPDNH_00605 398513.BBNG_00025 4.8e-259 900.2 Bifidobacteriales pstP GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 3.1.3.16 ko:K01090,ko:K20074 ko00000,ko01000,ko01009 Bacteria 2GJ3M@201174,4CZDN@85004,COG0631@1,COG0631@2 NA|NA|NA T Sigma factor PP2C-like phosphatases LPKNPDNH_00606 398513.BBNG_00026 7.9e-94 349.7 Bifidobacteriales fhaB GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944 Bacteria 2GKA7@201174,4D0RN@85004,COG1716@1,COG1716@2 NA|NA|NA T Inner membrane component of T3SS, cytoplasmic domain LPKNPDNH_00607 398513.BBNG_00027 1e-130 472.6 Bifidobacteriales fhaA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 ko:K02283 ko00000,ko02035,ko02044 Bacteria 2GNU2@201174,4CYUI@85004,COG1716@1,COG1716@2 NA|NA|NA T Protein of unknown function (DUF2662) LPKNPDNH_00608 398513.BBNG_00028 0.0 1740.7 Bifidobacteriales dpp4 3.4.14.5 ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Bacteria 2GJ6A@201174,4CZAE@85004,COG1506@1,COG1506@2 NA|NA|NA E Dipeptidyl peptidase IV (DPP IV) N-terminal region LPKNPDNH_00609 702459.BBPR_0110 0.0 1466.4 Bifidobacteriales pip ko:K01421 ko00000 Bacteria 2GKEM@201174,4CZ9R@85004,COG1511@1,COG1511@2 NA|NA|NA S YhgE Pip domain protein LPKNPDNH_00610 398513.BBNG_00030 1e-166 593.2 Bifidobacteriales pip ko:K01421 ko00000 Bacteria 2GKEM@201174,4CZ2A@85004,COG1511@1,COG1511@2 NA|NA|NA S YhgE Pip domain protein LPKNPDNH_00611 702459.BBPR_0111 1.8e-162 578.6 Bifidobacteriales pip ko:K01421 ko00000 Bacteria 2GKEM@201174,4CZ2A@85004,COG1511@1,COG1511@2 NA|NA|NA S YhgE Pip domain protein LPKNPDNH_00612 702459.BBPR_0112 1.9e-205 721.5 Bifidobacteriales pldB GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016740,GO:0016746,GO:0016747,GO:0016787,GO:0016788,GO:0044238,GO:0044464,GO:0052689,GO:0071704,GO:0071944 3.1.1.5 ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 iETEC_1333.ETEC_4102,iEcHS_1320.EcHS_A4049 Bacteria 2HZ9U@201174,4CZ5E@85004,COG2267@1,COG2267@2 NA|NA|NA I Serine aminopeptidase, S33 LPKNPDNH_00613 702459.BBPR_0113 6.2e-166 590.1 Bifidobacteriales yicL Bacteria 2HZCH@201174,4CZRZ@85004,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family LPKNPDNH_00614 398513.BBNG_00033 2e-103 382.1 Bifidobacteriales Bacteria 2BFMF@1,2IGC7@201174,329FS@2,4D0RD@85004 NA|NA|NA LPKNPDNH_00616 398513.BBNG_00035 5.4e-197 693.3 Bifidobacteriales msrA 1.8.4.11,1.8.4.12 ko:K07304,ko:K07305,ko:K12267 ko00000,ko01000 Bacteria 2GJ1S@201174,4CZXJ@85004,COG0225@1,COG0225@2,COG0229@1,COG0229@2 NA|NA|NA O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine LPKNPDNH_00618 702459.BBPR_0119 0.0 2108.2 Bifidobacteriales Bacteria 2GJ4Y@201174,4CZNN@85004,COG1061@1,COG1061@2,COG3886@1,COG3886@2 NA|NA|NA KL Domain of unknown function (DUF3427) LPKNPDNH_00619 702459.BBPR_0120 1.3e-90 339.0 Bifidobacteriales nudG GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55,3.6.1.65 ko:K03574,ko:K08320 ko00000,ko01000,ko03400 iE2348C_1286.E2348C_1887,iECP_1309.ECP_1705,iLF82_1304.LF82_1533,iNRG857_1313.NRG857_08815,iPC815.YPO2167,iSSON_1240.SSON_1397 Bacteria 2I2GY@201174,4D0UJ@85004,COG0494@1,COG0494@2 NA|NA|NA L NUDIX domain LPKNPDNH_00620 398513.BBNG_00039 3.3e-41 174.5 Actinobacteria ko:K07484,ko:K17763,ko:K21471 ko00000,ko01000,ko01002,ko01011,ko03021 Bacteria 2GWTP@201174,COG3599@1,COG3599@2 NA|NA|NA D DivIVA domain protein LPKNPDNH_00621 398513.BBNG_00041 9.3e-53 212.6 Bifidobacteriales ybjQ Bacteria 2IQNY@201174,4D0ZM@85004,COG0393@1,COG0393@2 NA|NA|NA S Putative heavy-metal-binding LPKNPDNH_00622 702459.BBPR_0123 3.8e-156 557.4 Bifidobacteriales Bacteria 2GNRY@201174,4D02B@85004,COG2267@1,COG2267@2 NA|NA|NA I Serine aminopeptidase, S33 LPKNPDNH_00623 702459.BBPR_0124 7e-86 323.2 Bifidobacteriales yjcF ko:K02348,ko:K07000 ko00000 Bacteria 2HZKP@201174,4D0UN@85004,COG2153@1,COG2153@2 NA|NA|NA Q Acetyltransferase (GNAT) domain LPKNPDNH_00624 702459.BBPR_0075 3.4e-32 144.1 Bacteria ko:K07483 ko00000 Bacteria COG2963@1,COG2963@2 NA|NA|NA L transposase activity LPKNPDNH_00625 702459.BBPR_0074 1.5e-53 215.3 Bifidobacteriales tnp7109-21 Bacteria 2GKDY@201174,4CZUB@85004,COG2801@1,COG2801@2 NA|NA|NA L Integrase core domain LPKNPDNH_00626 702459.BBPR_0074 5.6e-42 176.4 Bifidobacteriales tnp7109-21 Bacteria 2GKDY@201174,4CZUB@85004,COG2801@1,COG2801@2 NA|NA|NA L Integrase core domain LPKNPDNH_00627 1437609.BCAL_1721 6.4e-16 89.7 Bifidobacteriales Bacteria 2GISN@201174,4CZKR@85004,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase family LPKNPDNH_00628 566552.BIFCAT_01007 4.2e-08 63.2 Bifidobacteriales Bacteria 2A804@1,2IMWR@201174,30X0B@2,4D12R@85004 NA|NA|NA LPKNPDNH_00630 1120978.KB894081_gene83 3.2e-79 302.4 Bacilli Bacteria 1VBAK@1239,28JYK@1,2Z9NT@2,4HXCS@91061 NA|NA|NA L HindVP restriction endonuclease LPKNPDNH_00631 1120978.KB894081_gene82 7e-116 424.1 Bacilli dcm 2.1.1.37 ko:K00558,ko:K07486 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Bacteria 1TSNX@1239,4HFAI@91061,COG0270@1,COG0270@2 NA|NA|NA L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family LPKNPDNH_00632 566552.BIFCAT_01007 5.2e-33 146.7 Bifidobacteriales Bacteria 2A804@1,2IMWR@201174,30X0B@2,4D12R@85004 NA|NA|NA LPKNPDNH_00633 566552.BIFCAT_01008 1.1e-36 159.1 Bifidobacteriales CP_0155 3.5.1.28 ko:K01447,ko:K12204 R04112 RC00064,RC00141 ko00000,ko01000,ko02044 3.A.7.10.1,3.A.7.9.1 Bacteria 2I2HA@201174,4D2VG@85004,COG1388@1,COG1388@2 NA|NA|NA M LysM domain LPKNPDNH_00634 1437609.BCAL_1699 2.6e-57 228.4 Bifidobacteriales ko:K07273,ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 2I2GA@201174,4D07F@85004,COG1388@1,COG1388@2,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 LPKNPDNH_00635 327277.JHAL01000002_gene519 3.9e-15 86.7 Bifidobacteriales 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2IEJD@201174,4CZTH@85004,COG3677@1,COG3677@2 NA|NA|NA L Transposase, Mutator family LPKNPDNH_00637 702459.BBPR_0125 4.9e-259 899.8 Bifidobacteriales tgt 2.4.2.29 ko:K00773 R03789,R10209 RC00063 ko00000,ko01000,ko03016 Bacteria 2GMWY@201174,4CZNX@85004,COG0343@1,COG0343@2 NA|NA|NA F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) LPKNPDNH_00638 398513.BBNG_00046 3.9e-244 850.9 Bifidobacteriales degP ko:K08372 ko02020,map02020 ko00000,ko00001,ko01000,ko01002 Bacteria 2GJ96@201174,4CZAP@85004,COG0265@1,COG0265@2 NA|NA|NA O Domain present in PSD-95, Dlg, and ZO-1/2. LPKNPDNH_00639 398513.BBNG_00047 0.0 1347.4 Bifidobacteriales cadA Bacteria 2GIRF@201174,4CZ4F@85004,COG2217@1,COG2217@2 NA|NA|NA P E1-E2 ATPase LPKNPDNH_00640 398513.BBNG_00048 2.5e-272 944.1 Bifidobacteriales fprA 1.18.1.2,1.19.1.1 ko:K00528 R10159 ko00000,ko01000 Bacteria 2GJ4A@201174,4CZIT@85004,COG0493@1,COG0493@2 NA|NA|NA C Pyridine nucleotide-disulphide oxidoreductase LPKNPDNH_00641 702459.BBPR_0129 3.9e-173 614.0 Bifidobacteriales htpX GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03799 M00743 ko00000,ko00002,ko01000,ko01002 Bacteria 2GMJF@201174,4CYVY@85004,COG0501@1,COG0501@2 NA|NA|NA O Belongs to the peptidase M48B family LPKNPDNH_00643 398513.BBNG_00050 0.0 1098.6 Bifidobacteriales 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2I3IG@201174,4CZRW@85004,COG2865@1,COG2865@2 NA|NA|NA K Putative ATP-dependent DNA helicase recG C-terminal LPKNPDNH_00644 702459.BBPR_0180 1.9e-42 178.3 Bifidobacteriales Bacteria 2B58D@1,2GXSC@201174,31Y2C@2,4D1RP@85004 NA|NA|NA S Bacterial mobilisation protein (MobC) LPKNPDNH_00645 398513.BBNG_00052 2.3e-127 461.5 Bifidobacteriales Bacteria 2EUTA@1,2H4F7@201174,320NU@2,4D26P@85004 NA|NA|NA S Domain of unknown function (DUF4417) LPKNPDNH_00647 398513.BBNG_00054 1.9e-61 241.5 Bifidobacteriales Bacteria 2DVCN@1,2H9I5@201174,33VAZ@2,4D2EP@85004 NA|NA|NA LPKNPDNH_00648 398513.BBNG_00055 6.8e-65 253.1 Bacteria Bacteria 2F86X@1,340K7@2 NA|NA|NA LPKNPDNH_00649 398513.BBNG_00056 3.9e-50 203.8 Bifidobacteriales Bacteria 2GWRK@201174,4D1RT@85004,COG2856@1,COG2856@2 NA|NA|NA E IrrE N-terminal-like domain LPKNPDNH_00650 398513.BBNG_00056 2e-12 77.0 Bifidobacteriales Bacteria 2GWRK@201174,4D1RT@85004,COG2856@1,COG2856@2 NA|NA|NA E IrrE N-terminal-like domain LPKNPDNH_00651 398513.BBNG_00057 4.9e-57 226.9 Bifidobacteriales ko:K07110,ko:K21686 ko00000,ko03000 Bacteria 2H1A2@201174,4D1PI@85004,COG3093@1,COG3093@2 NA|NA|NA K Cro/C1-type HTH DNA-binding domain LPKNPDNH_00652 398513.BBNG_00058 2.5e-247 860.9 Bifidobacteriales 3.5.1.104 ko:K22278 ko00000,ko01000 Bacteria 2GN6G@201174,4D08Y@85004,COG0726@1,COG0726@2 NA|NA|NA G Polysaccharide deacetylase LPKNPDNH_00653 398513.BBNG_00059 1.2e-199 702.2 Bifidobacteriales fbaA GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 iZ_1308.Z4263 Bacteria 2GM5P@201174,4CZJI@85004,COG0191@1,COG0191@2 NA|NA|NA G Fructose-bisphosphate aldolase class-II LPKNPDNH_00654 398513.BBNG_00061 1.9e-250 871.3 Bifidobacteriales purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMP4@201174,4CZ0U@85004,COG0104@1,COG0104@2 NA|NA|NA F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP LPKNPDNH_00655 398513.BBNG_00062 3.7e-163 580.9 Bifidobacteriales ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria 2IC26@201174,4D0RK@85004,COG0239@1,COG0239@2 NA|NA|NA U Important for reducing fluoride concentration in the cell, thus reducing its toxicity LPKNPDNH_00656 702459.BBPR_0142 1.5e-59 235.3 Bifidobacteriales crcB ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria 2IC26@201174,4D14T@85004,COG0239@1,COG0239@2 NA|NA|NA U Important for reducing fluoride concentration in the cell, thus reducing its toxicity LPKNPDNH_00657 702459.BBPR_0143 8.4e-193 679.5 Bifidobacteriales ko:K02529,ko:K03484 ko00000,ko03000 Bacteria 2GMHV@201174,4CZ3G@85004,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor LPKNPDNH_00658 702459.BBPR_0144 4.8e-78 297.0 Bifidobacteriales gtfA GO:0003674,GO:0003824,GO:0004645,GO:0005975,GO:0005976,GO:0006066,GO:0006073,GO:0008150,GO:0008152,GO:0009018,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0019400,GO:0019751,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0051472,GO:0071704,GO:1901615 2.4.1.329,2.4.1.7 ko:K00690,ko:K21350 ko00500,map00500 R00803 RC00028 ko00000,ko00001,ko01000 GH13 Bacteria 2GNEC@201174,4CZ4T@85004,COG0366@1,COG0366@2 NA|NA|NA G Domain of unknown function (DUF1964) LPKNPDNH_00659 702459.BBPR_0145 7e-298 1029.2 Bifidobacteriales scrT Bacteria 2GJZG@201174,4CZ93@85004,COG2211@1,COG2211@2 NA|NA|NA G Transporter major facilitator family protein LPKNPDNH_00660 702459.BBPR_0146 5e-254 883.2 Bifidobacteriales yhjE Bacteria 2GIYR@201174,4CYY8@85004,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter LPKNPDNH_00661 398513.BBNG_00068 2.8e-204 717.6 Bifidobacteriales ilvC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKXA@201174,4CZBR@85004,COG0059@1,COG0059@2 NA|NA|NA H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate LPKNPDNH_00662 398513.BBNG_00069 8.2e-204 716.1 Bifidobacteriales ilvC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKXA@201174,4CZBR@85004,COG0059@1,COG0059@2 NA|NA|NA H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate LPKNPDNH_00663 702459.BBPR_0149 8.8e-184 649.4 Bifidobacteriales gmk 1.1.1.23,2.7.4.8 ko:K00013,ko:K00942 ko00230,ko00340,ko01100,ko01110,ko01230,map00230,map00340,map01100,map01110,map01230 M00026,M00050 R00332,R01158,R01163,R02090,R03012 RC00002,RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN40@201174,4CZJT@85004,COG2852@1,COG2852@2 NA|NA|NA S Protein of unknown function (DUF559) LPKNPDNH_00665 702459.BBPR_0150 0.0 2517.3 Bifidobacteriales lacZ 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 Bacteria 2GMAT@201174,4CYYS@85004,COG3250@1,COG3250@2 NA|NA|NA G Psort location Cytoplasmic, score 8.87 LPKNPDNH_00666 702459.BBPR_0151 1.8e-276 958.0 Bifidobacteriales aroP GO:0003333,GO:0003674,GO:0005215,GO:0005302,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008104,GO:0008150,GO:0008320,GO:0008324,GO:0008509,GO:0008514,GO:0008565,GO:0009977,GO:0015031,GO:0015075,GO:0015171,GO:0015173,GO:0015179,GO:0015192,GO:0015196,GO:0015238,GO:0015291,GO:0015318,GO:0015399,GO:0015405,GO:0015450,GO:0015711,GO:0015801,GO:0015807,GO:0015823,GO:0015827,GO:0015828,GO:0015833,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0033036,GO:0034220,GO:0042221,GO:0042493,GO:0042886,GO:0042887,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1904680,GO:1905039 ko:K03293,ko:K11732,ko:K11734 ko00000,ko02000 2.A.3.1,2.A.3.1.1,2.A.3.1.3 iAPECO1_1312.APECO1_1472,iECW_1372.ECW_m0628,iEcE24377_1341.EcE24377A_0114,iEcolC_1368.EcolC_3070,iJN746.PP_4495,iUTI89_1310.UTI89_C0576,iWFL_1372.ECW_m0628 Bacteria 2GJ0X@201174,4CZ4X@85004,COG1113@1,COG1113@2 NA|NA|NA E aromatic amino acid transport protein AroP K03293 LPKNPDNH_00667 398513.BBNG_00075 2.4e-101 374.8 Bifidobacteriales Bacteria 2HZBI@201174,4CZJ8@85004,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator C-terminal region LPKNPDNH_00668 398513.BBNG_00076 2.6e-129 468.0 Bifidobacteriales ko:K02003,ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GJQV@201174,4CYT2@85004,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter LPKNPDNH_00669 398513.BBNG_00077 0.0 1539.6 Bifidobacteriales ko:K02004,ko:K06994 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2I2FK@201174,4CZJR@85004,COG0577@1,COG0577@2,COG1511@1,COG1511@2 NA|NA|NA V FtsX-like permease family LPKNPDNH_00670 398513.BBNG_00078 8.6e-84 316.2 Bifidobacteriales rlmH 2.1.1.177 ko:K00783 ko00000,ko01000,ko03009 Bacteria 2IJE0@201174,4D0P5@85004,COG1576@1,COG1576@2 NA|NA|NA J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA LPKNPDNH_00671 398513.BBNG_00079 6.7e-116 423.3 Bifidobacteriales upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000 Bacteria 2GPJE@201174,4CYVS@85004,COG0035@1,COG0035@2 NA|NA|NA F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate LPKNPDNH_00672 702459.BBPR_0157 1.2e-39 168.7 Bifidobacteriales ko:K01996 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 2GKSQ@201174,4D0EB@85004,COG0410@1,COG0410@2 NA|NA|NA E ABC transporter LPKNPDNH_00673 398513.BBNG_00081 7.6e-100 369.8 Bifidobacteriales bcp GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0032843,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 ko:K03564 ko00000,ko01000 iPC815.YPO3064 Bacteria 2IHZ6@201174,4D0PN@85004,COG1225@1,COG1225@2 NA|NA|NA O Redoxin LPKNPDNH_00674 702459.BBPR_0159 1.1e-151 542.7 Bifidobacteriales ko:K07058 ko00000 Bacteria 2GN79@201174,4CZM4@85004,COG1295@1,COG1295@2 NA|NA|NA S Virulence factor BrkB LPKNPDNH_00675 398513.BBNG_00083 4.2e-42 176.8 Bifidobacteriales XAC3035 ko:K06191 ko00000 Bacteria 2HZQB@201174,4D18H@85004,COG0695@1,COG0695@2 NA|NA|NA O Glutaredoxin LPKNPDNH_00676 702459.BBPR_0161 1.6e-105 389.0 Bifidobacteriales GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 ko:K07485 ko00000 Bacteria 2GJK7@201174,4D0ME@85004,COG3464@1,COG3464@2 NA|NA|NA L Transposase LPKNPDNH_00677 398513.BBNG_00086 0.0 1526.9 Bifidobacteriales yvnB 3.1.4.53 ko:K03651 ko00230,ko02025,map00230,map02025 R00191 RC00296 ko00000,ko00001,ko01000 Bacteria 2GNU9@201174,4CZXA@85004,COG1409@1,COG1409@2 NA|NA|NA S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes LPKNPDNH_00678 702459.BBPR_0164 0.0 1498.0 Bifidobacteriales bga1 3.2.1.23 ko:K12308 ko00052,map00052 R01105 RC00452 ko00000,ko00001,ko01000 Bacteria 2GMDT@201174,4CZ38@85004,COG1874@1,COG1874@2 NA|NA|NA G Psort location Cytoplasmic, score 8.87 LPKNPDNH_00679 398513.BBNG_00090 5.5e-55 219.9 Bifidobacteriales ko:K07454 ko00000 Bacteria 2HZE0@201174,4CZZR@85004,COG3440@1,COG3440@2 NA|NA|NA L HNH endonuclease LPKNPDNH_00680 398513.BBNG_00091 2.9e-243 847.4 Bifidobacteriales 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2I3IG@201174,4CZRW@85004,COG2865@1,COG2865@2 NA|NA|NA K Putative ATP-dependent DNA helicase recG C-terminal LPKNPDNH_00681 398513.BBNG_00092 1.2e-132 479.2 Bifidobacteriales Bacteria 2B6TG@1,2H2MS@201174,31ZSS@2,4D1XE@85004 NA|NA|NA LPKNPDNH_00682 216816.GS08_00950 1.5e-265 921.8 Bifidobacteriales Bacteria 2GIUM@201174,4D0BX@85004,COG0477@1,COG0477@2 NA|NA|NA EGP Major Facilitator Superfamily LPKNPDNH_00683 702459.BBPR_0169 3.5e-41 173.7 Bifidobacteriales 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2HZQU@201174,4D1A9@85004,COG0331@1,COG0331@2 NA|NA|NA IQ [acyl-carrier-protein] S-malonyltransferase activity LPKNPDNH_00684 702459.BBPR_0170 2.1e-134 485.0 Bifidobacteriales Bacteria 2GKDY@201174,4CZQK@85004,COG2801@1,COG2801@2 NA|NA|NA L Integrase core domain LPKNPDNH_00685 216816.GS08_10200 3.6e-37 160.6 Bifidobacteriales ko:K07483 ko00000 Bacteria 2IRD7@201174,4D16D@85004,COG2963@1,COG2963@2 NA|NA|NA L Psort location Cytoplasmic, score 8.87 LPKNPDNH_00686 702459.BBPR_0172 5e-116 423.7 Bifidobacteriales Bacteria 2IRA8@201174,4D0DY@85004,COG1309@1,COG1309@2 NA|NA|NA K WHG domain LPKNPDNH_00687 702459.BBPR_0173 1.4e-90 339.0 Bifidobacteriales pptA 6.3.2.14 ko:K02362 ko01053,ko01110,ko01130,map01053,map01110,map01130 R07644 RC00162,RC03046 ko00000,ko00001,ko01000 Bacteria 2IIA2@201174,4D0IW@85004,COG2977@1,COG2977@2 NA|NA|NA Q 4'-phosphopantetheinyl transferase superfamily LPKNPDNH_00688 216816.GS08_08800 1.4e-13 81.6 Bifidobacteriales Bacteria 29RY3@1,2GWAQ@201174,30D2D@2,4D1M1@85004 NA|NA|NA LPKNPDNH_00689 702459.BBPR_0174 5.6e-272 943.0 Bifidobacteriales Bacteria 28NJJ@1,2IBUV@201174,2ZBKQ@2,4D0QK@85004 NA|NA|NA LPKNPDNH_00690 702459.BBPR_0175 7.6e-299 1032.3 Bifidobacteriales hsdM 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 2GKAQ@201174,4CZNR@85004,COG0286@1,COG0286@2 NA|NA|NA V modification (methylase) protein of type I restriction-modification system K03427 LPKNPDNH_00692 702459.BBPR_0177 6.5e-229 799.7 Bifidobacteriales 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 2IAIR@201174,4D0YU@85004,COG0732@1,COG0732@2 NA|NA|NA V Type I restriction modification DNA specificity domain LPKNPDNH_00693 702459.BBPR_0178 2e-180 638.3 Bifidobacteriales Bacteria 2IDRD@201174,4D0BJ@85004,COG4823@1,COG4823@2 NA|NA|NA V Abi-like protein LPKNPDNH_00694 702459.BBPR_0179 0.0 2006.5 Bifidobacteriales hsdR 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 2HI69@201174,4CZER@85004,COG0610@1,COG0610@2 NA|NA|NA V Subunit R is required for both nuclease and ATPase activities, but not for modification LPKNPDNH_00695 702459.BBPR_0180 1.4e-59 235.3 Bifidobacteriales Bacteria 2B58D@1,2GXSC@201174,31Y2C@2,4D1RP@85004 NA|NA|NA S Bacterial mobilisation protein (MobC) LPKNPDNH_00696 702459.BBPR_0181 0.0 1196.0 Bifidobacteriales ltrBE1 Bacteria 2GKSD@201174,4CZZ8@85004,COG3843@1,COG3843@2 NA|NA|NA U Relaxase/Mobilisation nuclease domain LPKNPDNH_00697 702459.BBPR_0182 4.7e-105 387.1 Bifidobacteriales Bacteria 2BK84@1,2HZY8@201174,32EN2@2,4D27Z@85004 NA|NA|NA LPKNPDNH_00700 702459.BBPR_0184 1.3e-258 898.7 Bifidobacteriales Bacteria 2GISN@201174,4D0EV@85004,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase, N-terminal SAM-like domain LPKNPDNH_00702 398513.BBNG_00100 7.9e-17 92.0 Bacteria Bacteria COG3227@1,COG3227@2,COG5520@1,COG5520@2 NA|NA|NA M Belongs to the glycosyl hydrolase 30 family LPKNPDNH_00703 398513.BBNG_00100 4e-100 370.9 Bacteria Bacteria COG3227@1,COG3227@2,COG5520@1,COG5520@2 NA|NA|NA M Belongs to the glycosyl hydrolase 30 family LPKNPDNH_00705 702459.BBPR_0188 3.3e-191 674.1 Bifidobacteriales 1.1.1.65 ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 R01708 RC00116 ko00000,ko00001,ko01000 Bacteria 2GJ6R@201174,4CZ9P@85004,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family LPKNPDNH_00706 398513.BBNG_00103 2e-43 181.4 Bifidobacteriales Bacteria 2B12Y@1,2GSE7@201174,31TGH@2,4D1GD@85004 NA|NA|NA S Protein of unknown function (DUF1778) LPKNPDNH_00707 398513.BBNG_00104 5.9e-94 350.1 Bifidobacteriales ydgJ Bacteria 2IMKE@201174,4CYZZ@85004,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein LPKNPDNH_00708 398513.BBNG_00105 0.0 1159.1 Bifidobacteriales lmrA1 ko:K02021,ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 Bacteria 2GITR@201174,4CYYV@85004,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter, ATP-binding protein LPKNPDNH_00709 702459.BBPR_0192 0.0 1262.7 Bifidobacteriales lmrA2 ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2GITR@201174,4CZTU@85004,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region LPKNPDNH_00710 398513.BBNG_00107 0.0 3280.3 Bifidobacteriales 3.2.1.51 ko:K15923 ko00511,map00511 ko00000,ko00001,ko01000 GH95 Bacteria 2GJXJ@201174,4CZZK@85004,COG1554@1,COG1554@2,COG3210@1,COG3210@2 NA|NA|NA G Glycosyl hydrolase family 65, N-terminal domain LPKNPDNH_00711 398513.BBNG_00108 1.3e-107 395.6 Bifidobacteriales ko:K06910 ko00000 Bacteria 2I5K1@201174,4CZSW@85004,COG1881@1,COG1881@2 NA|NA|NA S Phosphatidylethanolamine-binding protein LPKNPDNH_00712 702459.BBPR_0195 0.0 1094.7 Bifidobacteriales pepD ko:K08659 ko00000,ko01000,ko01002 Bacteria 2GM80@201174,4CZI5@85004,COG4690@1,COG4690@2 NA|NA|NA E Peptidase family C69 LPKNPDNH_00713 398513.BBNG_00110 1.3e-287 995.0 Bifidobacteriales fhs GO:0000096,GO:0000097,GO:0000105,GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006520,GO:0006547,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009108,GO:0009110,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0052803,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.5,3.5.4.9,6.3.4.3 ko:K00288,ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00141,M00377 R00943,R01220,R01655 RC00026,RC00111,RC00202,RC00578 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GT0X@201174,4CZ7P@85004,COG2759@1,COG2759@2 NA|NA|NA F Formate-tetrahydrofolate ligase LPKNPDNH_00714 398513.BBNG_00111 1.3e-62 245.4 Bifidobacteriales Bacteria 2II0W@201174,4D0VC@85004,COG1942@1,COG1942@2 NA|NA|NA S Macrophage migration inhibitory factor (MIF) LPKNPDNH_00715 702459.BBPR_0198 6.8e-98 363.2 Bifidobacteriales Bacteria 2HZBR@201174,4CZM6@85004,COG2246@1,COG2246@2 NA|NA|NA S GtrA-like protein LPKNPDNH_00716 398513.BBNG_00113 4e-262 910.2 Bifidobacteriales Bacteria 2GKMQ@201174,4CZ6D@85004,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily LPKNPDNH_00717 398513.BBNG_00114 1.1e-126 459.1 Bifidobacteriales 3.1.3.3,3.1.3.73 ko:K02226,ko:K22305 ko00260,ko00680,ko00860,ko01100,ko01120,ko01130,map00260,map00680,map00860,map01100,map01120,map01130 M00122 R00582,R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMXF@201174,4CZ0Z@85004,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family LPKNPDNH_00718 398513.BBNG_00115 5.8e-145 520.4 Bifidobacteriales Bacteria 2BR5C@1,2I8T9@201174,32K3E@2,4CZ8U@85004 NA|NA|NA LPKNPDNH_00719 398513.BBNG_00116 1.7e-137 495.4 Bifidobacteriales ytlD1 2.7.1.50 ko:K00878,ko:K15599 ko00730,ko01100,ko02010,map00730,map01100,map02010 M00127,M00442 R04448 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.17.3,3.A.1.17.6 Bacteria 2GKKZ@201174,4CZ9Q@85004,COG0600@1,COG0600@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component LPKNPDNH_00720 398513.BBNG_00117 8.6e-201 706.1 Bifidobacteriales ko:K02051 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 2HZ9T@201174,4CZ56@85004,COG0715@1,COG0715@2 NA|NA|NA P NMT1/THI5 like LPKNPDNH_00721 398513.BBNG_00118 1.1e-124 452.6 Bifidobacteriales Bacteria 2GJNG@201174,4CYZV@85004,COG0637@1,COG0637@2 NA|NA|NA S HAD hydrolase, family IA, variant 3 LPKNPDNH_00723 398513.BBNG_00120 6.3e-298 1029.2 Bifidobacteriales gltX GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 iNJ661.Rv2992c Bacteria 2GJJS@201174,4CZHK@85004,COG0008@1,COG0008@2 NA|NA|NA J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) LPKNPDNH_00724 702459.BBPR_0206 5.6e-103 380.2 Bifidobacteriales ko:K07133 ko00000 Bacteria 2GK1Q@201174,4CZNQ@85004,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) LPKNPDNH_00725 702459.BBPR_0207 3.5e-67 260.8 Bifidobacteriales ko:K07133 ko00000 Bacteria 2GK1Q@201174,4CZNQ@85004,COG1373@1,COG1373@2 NA|NA|NA S Domain of unknown function (DUF4143) LPKNPDNH_00728 398513.BBNG_00122 2.2e-251 874.4 Bifidobacteriales Bacteria 2HRDZ@201174,4CYQR@85004,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase LPKNPDNH_00729 702459.BBPR_0209 8.2e-138 496.5 Bifidobacteriales ltbR Bacteria 2GKB0@201174,4CZ9D@85004,COG1414@1,COG1414@2 NA|NA|NA K Transcriptional regulator, IclR family, C-terminal domain protein LPKNPDNH_00730 398513.BBNG_00124 2.2e-273 947.6 Bifidobacteriales leuC GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 iEcE24377_1341.EcE24377A_0075,iPC815.YPO0531 Bacteria 2GKT7@201174,4CYUC@85004,COG0065@1,COG0065@2 NA|NA|NA E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate LPKNPDNH_00731 398513.BBNG_00125 3.8e-133 480.7 Bifidobacteriales leuD GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2987c Bacteria 2GJ8Z@201174,4CZ2F@85004,COG0066@1,COG0066@2 NA|NA|NA E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate LPKNPDNH_00732 398513.BBNG_00126 0.0 2594.3 Bifidobacteriales snf 2.7.11.1 ko:K08282 ko00000,ko01000 Bacteria 2GISC@201174,4CZSD@85004,COG0553@1,COG0553@2 NA|NA|NA KL Psort location Cytoplasmic, score 8.87 LPKNPDNH_00734 398513.BBNG_00130 7.1e-182 643.3 Bifidobacteriales ko:K07052 ko00000 Bacteria 2I3DW@201174,4CZJZ@85004,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity LPKNPDNH_00735 398513.BBNG_00131 2.3e-220 771.2 Bifidobacteriales pyrD 1.3.1.14 ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01869 RC00051 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJMN@201174,4CZKM@85004,COG0167@1,COG0167@2 NA|NA|NA F Dihydroorotate dehydrogenase LPKNPDNH_00736 398513.BBNG_00133 9.8e-255 885.6 Bifidobacteriales murA 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 R00660 RC00350 ko00000,ko00001,ko01000,ko01011 Bacteria 2GJPW@201174,4CZN7@85004,COG0766@1,COG0766@2 NA|NA|NA M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine LPKNPDNH_00737 398513.BBNG_00134 2.6e-158 564.7 Bifidobacteriales Bacteria 2HZ9S@201174,4CZ4Z@85004,COG2271@1,COG2271@2 NA|NA|NA G Transmembrane secretion effector LPKNPDNH_00738 702459.BBPR_0218 1.7e-50 205.3 Bifidobacteriales Bacteria 2HZ9S@201174,4CZ4Z@85004,COG2271@1,COG2271@2 NA|NA|NA G Transmembrane secretion effector LPKNPDNH_00739 398513.BBNG_00135 2.1e-131 474.9 Bifidobacteriales Bacteria 2HZJX@201174,4D0QJ@85004,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family LPKNPDNH_00740 398513.BBNG_00136 4.9e-128 464.2 Bifidobacteriales Bacteria 29W7A@1,2IQ2G@201174,30HSH@2,4D15I@85004 NA|NA|NA LPKNPDNH_00741 398513.BBNG_00138 2.3e-72 278.1 Bifidobacteriales rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02867 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IFCK@201174,4D0PA@85004,COG0080@1,COG0080@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors LPKNPDNH_00742 398513.BBNG_00139 6.1e-123 446.8 Bifidobacteriales rplA GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02863 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GM51@201174,4CZFR@85004,COG0081@1,COG0081@2 NA|NA|NA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release LPKNPDNH_00743 702459.BBPR_0223 1.2e-164 585.9 Bifidobacteriales fkbB 5.2.1.8 ko:K01802 ko00000,ko01000 Bacteria 2GJK2@201174,4CZEF@85004,COG0545@1,COG0545@2 NA|NA|NA M FKBP-type peptidyl-prolyl cis-trans isomerase LPKNPDNH_00744 398513.BBNG_00141 5.8e-189 666.8 Bifidobacteriales Bacteria 2DMQ0@1,2IA0N@201174,32SYI@2,4CYQ0@85004 NA|NA|NA LPKNPDNH_00745 398513.BBNG_00142 7.9e-180 636.3 Bifidobacteriales Bacteria 28PR0@1,2GNNZ@201174,2ZCCY@2,4CYX7@85004 NA|NA|NA LPKNPDNH_00746 398513.BBNG_00143 8.5e-163 579.7 Bifidobacteriales trxA2 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 ko:K03671,ko:K05838 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 2GJ7B@201174,4CZHU@85004,COG3118@1,COG3118@2 NA|NA|NA O Tetratricopeptide repeat LPKNPDNH_00747 702459.BBPR_0227 1.4e-118 432.2 Bifidobacteriales cyaA GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0050355 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 Bacteria 2GWD8@201174,4CZKD@85004,COG2954@1,COG2954@2 NA|NA|NA S CYTH LPKNPDNH_00750 702459.BBPR_0228 6.3e-185 653.3 Bifidobacteriales ko:K02529,ko:K17640 ko00000,ko03000 Bacteria 2GJRG@201174,4CZI0@85004,COG1609@1,COG1609@2 NA|NA|NA K Bacterial regulatory proteins, lacI family LPKNPDNH_00751 702459.BBPR_0229 5.3e-18 95.9 Bacteria 4.2.1.68 ko:K18334 ko00051,ko01120,map00051,map01120 R03688 RC00543 ko00000,ko00001,ko01000 Bacteria COG4948@1,COG4948@2 NA|NA|NA M carboxylic acid catabolic process LPKNPDNH_00752 702459.BBPR_0230 6.7e-65 253.1 Bifidobacteriales 4.2.1.68 ko:K18334 ko00051,ko01120,map00051,map01120 R03688 RC00543 ko00000,ko00001,ko01000 Bacteria 2GKSK@201174,4D0EI@85004,COG4948@1,COG4948@2 NA|NA|NA M Enolase C-terminal domain-like LPKNPDNH_00753 702459.BBPR_0231 6.8e-164 583.2 Bifidobacteriales Bacteria 2GJGM@201174,4CZXI@85004,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain LPKNPDNH_00755 702459.BBPR_0233 0.0 1563.9 Bifidobacteriales gnpA GO:0003674,GO:0003824,GO:0004645,GO:0005975,GO:0008150,GO:0008152,GO:0016740,GO:0016757,GO:0016758,GO:0044238,GO:0050500,GO:0071704 2.4.1.211 ko:K15533 ko00000,ko01000 Bacteria 2GN2A@201174,4CYZB@85004,COG5426@1,COG5426@2 NA|NA|NA S Lacto-N-biose phosphorylase C-terminal domain LPKNPDNH_00756 398513.BBNG_00150 5.2e-63 246.9 Bifidobacteriales psp1 3.5.99.10 ko:K09022 R11098,R11099 RC03275,RC03354 ko00000,ko01000 Bacteria 2IFCR@201174,4D0QD@85004,COG0251@1,COG0251@2 NA|NA|NA J Endoribonuclease L-PSP LPKNPDNH_00757 702459.BBPR_0235 4.7e-182 643.7 Bifidobacteriales 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 2HZMC@201174,4D0XD@85004,COG0584@1,COG0584@2 NA|NA|NA C Glycerophosphoryl diester phosphodiesterase family LPKNPDNH_00758 702459.BBPR_0236 0.0 1181.0 Bifidobacteriales argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iAF987.Gmet_1434 Bacteria 2GKQ3@201174,4CZ9J@85004,COG0018@1,COG0018@2 NA|NA|NA J Arginyl-tRNA synthetase LPKNPDNH_00759 702459.BBPR_0238 1e-108 399.4 Bifidobacteriales lysA 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKAI@201174,4CYRG@85004,COG0019@1,COG0019@2 NA|NA|NA E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine LPKNPDNH_00760 702459.BBPR_0238 3e-187 661.0 Bifidobacteriales lysA 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKAI@201174,4CYRG@85004,COG0019@1,COG0019@2 NA|NA|NA E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine LPKNPDNH_00761 702459.BBPR_0239 2.7e-40 171.0 Bifidobacteriales 2.7.1.208 ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12 Bacteria 2INQB@201174,4D11R@85004,COG2190@1,COG2190@2 NA|NA|NA G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 LPKNPDNH_00762 398513.BBNG_00155 1.9e-289 1001.1 Bifidobacteriales nagE 2.7.1.193,2.7.1.199 ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 M00267,M00809 R02738,R05199 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.13,4.A.1.1.14,4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7,4.A.1.1.9 iSB619.SA_RS08720 Bacteria 2GKPM@201174,4D069@85004,COG1263@1,COG1263@2,COG1264@1,COG1264@2 NA|NA|NA G phosphotransferase system, EIIB LPKNPDNH_00763 702459.BBPR_0241 1.8e-240 838.2 Bifidobacteriales hom GO:0003674,GO:0003824,GO:0004412,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1294,iSB619.SA_RS06610 Bacteria 2GIX9@201174,4CZVD@85004,COG0460@1,COG0460@2 NA|NA|NA E Homoserine dehydrogenase LPKNPDNH_00764 398513.BBNG_00157 5.4e-189 666.8 Bifidobacteriales thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_0003,iJN678.thrB,iLJ478.TM0545,iSB619.SA_RS06620 Bacteria 2GKIW@201174,4CZN0@85004,COG0083@1,COG0083@2 NA|NA|NA E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate LPKNPDNH_00765 398513.BBNG_00158 1.1e-280 971.8 Bifidobacteriales maf GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047429 1.1.1.25,2.1.1.190,3.6.1.55,3.6.1.67 ko:K00014,ko:K03215,ko:K03574,ko:K06287,ko:K08310 ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00400,map00790,map01100,map01110,map01130,map01230 M00022,M00126 R02413,R04638 RC00002,RC00206 ko00000,ko00001,ko00002,ko01000,ko03009,ko03400 Bacteria 2GNI0@201174,4CZXF@85004,COG0424@1,COG0424@2,COG1051@1,COG1051@2 NA|NA|NA DF Maf-like protein LPKNPDNH_00766 398513.BBNG_00159 9.9e-67 259.2 Bifidobacteriales Bacteria 2B304@1,2GVW8@201174,31VMB@2,4D2FV@85004 NA|NA|NA LPKNPDNH_00767 398513.BBNG_00160 6.8e-57 226.5 Bifidobacteriales Bacteria 2B66H@1,2H1MR@201174,31Z3P@2,4D2PR@85004 NA|NA|NA LPKNPDNH_00768 398513.BBNG_00161 8.3e-165 586.3 Bifidobacteriales ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GM25@201174,4D0FV@85004,COG1136@1,COG1136@2 NA|NA|NA V ATPases associated with a variety of cellular activities LPKNPDNH_00769 398513.BBNG_00162 3.3e-256 890.6 Bifidobacteriales ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GKF3@201174,4D03X@85004,COG0577@1,COG0577@2 NA|NA|NA V Efflux ABC transporter, permease protein LPKNPDNH_00770 398513.BBNG_00163 2.2e-168 598.2 Bifidobacteriales mdcF ko:K07088 ko00000 Bacteria 2GNIA@201174,4CZFX@85004,COG0679@1,COG0679@2 NA|NA|NA S Transporter, auxin efflux carrier (AEC) family protein LPKNPDNH_00771 702459.BBPR_0249 1.7e-240 838.2 Bifidobacteriales dapE 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK09@201174,4CZ9K@85004,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain LPKNPDNH_00772 702459.BBPR_0251 0.0 1313.5 Bifidobacteriales rne GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 3.1.26.12 ko:K08300,ko:K08301 ko03018,map03018 M00394 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Bacteria 2GMM5@201174,4CYQT@85004,COG1530@1,COG1530@2 NA|NA|NA J Ribonuclease E/G family LPKNPDNH_00773 398513.BBNG_00166 3.2e-47 194.1 Bifidobacteriales rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02888 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ9A@201174,4D10B@85004,COG0261@1,COG0261@2 NA|NA|NA J This protein binds to 23S rRNA in the presence of protein L20 LPKNPDNH_00774 398513.BBNG_00167 3.1e-40 170.6 Bifidobacteriales rpmA GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 ko:K02899 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQDI@201174,4D19N@85004,COG0211@1,COG0211@2 NA|NA|NA J Ribosomal L27 protein LPKNPDNH_00775 702459.BBPR_0254 4.8e-215 753.4 Bifidobacteriales Bacteria 2ICPH@201174,4CZJ7@85004,COG5340@1,COG5340@2 NA|NA|NA K Psort location Cytoplasmic, score LPKNPDNH_00776 398513.BBNG_00169 1.4e-298 1031.6 Bifidobacteriales obg GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904 ko:K03979 ko00000,ko01000,ko03009 Bacteria 2GISB@201174,4CYWD@85004,COG0536@1,COG0536@2 NA|NA|NA S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control LPKNPDNH_00777 398513.BBNG_00170 4.1e-201 707.2 Bifidobacteriales proB GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM8U@201174,4CZ2B@85004,COG0263@1,COG0263@2 NA|NA|NA E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate LPKNPDNH_00778 398513.BBNG_00171 4e-231 807.0 Bifidobacteriales aspC Bacteria 2GJ7R@201174,4CZFY@85004,COG0436@1,COG0436@2 NA|NA|NA E DegT/DnrJ/EryC1/StrS aminotransferase family LPKNPDNH_00780 398513.BBNG_00172 4.7e-32 143.3 Bifidobacteriales secE GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 2HZQC@201174,4D18K@85004,COG0690@1,COG0690@2 NA|NA|NA U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation LPKNPDNH_00781 398513.BBNG_00173 1.8e-116 425.6 Bifidobacteriales nusG GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K02601 ko00000,ko03009,ko03021 Bacteria 2GJFW@201174,4CYSH@85004,COG0250@1,COG0250@2 NA|NA|NA K Participates in transcription elongation, termination and antitermination LPKNPDNH_00782 398513.BBNG_00174 2.8e-173 614.4 Bifidobacteriales plsC2 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2GKVA@201174,4CZG0@85004,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases LPKNPDNH_00783 398513.BBNG_00175 2.5e-178 631.3 Bifidobacteriales gpsA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 R00842,R00844 RC00029 ko00000,ko00001,ko01000 Bacteria 2GJSD@201174,4CZHP@85004,COG0240@1,COG0240@2 NA|NA|NA I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus LPKNPDNH_00784 398513.BBNG_00176 3.4e-219 767.3 Bifidobacteriales ddl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008716,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016874,GO:0016879,GO:0016881,GO:0044424,GO:0044444,GO:0044464,GO:0050896 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 iAF1260.b0381,iB21_1397.B21_00332,iBWG_1329.BWG_0265,iE2348C_1286.E2348C_0317,iEC042_1314.EC042_0413,iEC55989_1330.EC55989_0386,iECBD_1354.ECBD_3283,iECB_1328.ECB_00328,iECDH10B_1368.ECDH10B_0338,iECDH1ME8569_1439.ECDH1ME8569_0367,iECD_1391.ECD_00328,iECH74115_1262.ECH74115_0453,iECIAI1_1343.ECIAI1_0377,iECIAI39_1322.ECIAI39_0301,iECO103_1326.ECO103_0356,iECO111_1330.ECO111_0411,iECO26_1355.ECO26_0414,iECSE_1348.ECSE_0401,iECSP_1301.ECSP_0441,iECs_1301.ECs0431,iETEC_1333.ETEC_0434,iEcDH1_1363.EcDH1_3227,iEcE24377_1341.EcE24377A_0406,iEcHS_1320.EcHS_A0447,iEcSMS35_1347.EcSMS35_0410,iEcolC_1368.EcolC_3251,iJO1366.b0381,iJR904.b0381,iSF_1195.SF0232,iSFxv_1172.SFxv_0245,iS_1188.S0254,iUMNK88_1353.UMNK88_429,iY75_1357.Y75_RS01965,iZ_1308.Z0477 Bacteria 2GITC@201174,4CZ1R@85004,COG1181@1,COG1181@2 NA|NA|NA F Belongs to the D-alanine--D-alanine ligase family LPKNPDNH_00785 702459.BBPR_0263 7.5e-202 709.5 Bifidobacteriales ugpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 2GNM5@201174,4CYS4@85004,COG0584@1,COG0584@2 NA|NA|NA C Glycerophosphoryl diester phosphodiesterase family LPKNPDNH_00786 398513.BBNG_00178 0.0 3595.8 Bifidobacteriales 3.2.1.97 ko:K02004,ko:K17624 M00258 ko00000,ko00002,ko01000,ko02000 3.A.1 GH101 Bacteria 2I615@201174,4CZVH@85004,COG0366@1,COG0366@2,COG1196@1,COG1196@2 NA|NA|NA G Glycosyl hydrolase 101 beta sandwich domain LPKNPDNH_00787 398513.BBNG_00179 6.9e-192 676.4 Bifidobacteriales prs GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ9S@201174,4CZPM@85004,COG0462@1,COG0462@2 NA|NA|NA F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) LPKNPDNH_00788 398513.BBNG_00180 0.0 1444.9 Bifidobacteriales ftsK 2.7.11.1,2.7.7.7,3.4.21.110,4.2.1.2 ko:K01679,ko:K02343,ko:K02519,ko:K03466,ko:K03591,ko:K03642,ko:K03749,ko:K05802,ko:K08652,ko:K12132,ko:K13733,ko:K14194,ko:K14195,ko:K18491,ko:K20382 ko00020,ko00230,ko00240,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02024,ko03030,ko03430,ko03440,ko04550,ko04934,ko05100,ko05150,ko05200,ko05211,map00020,map00230,map00240,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map02024,map03030,map03430,map03440,map04550,map04934,map05100,map05150,map05200,map05211 M00009,M00011,M00173,M00260,M00376 R00375,R00376,R00377,R00378,R01082 RC00443,RC02795 ko00000,ko00001,ko00002,ko01000,ko01001,ko01002,ko02000,ko03000,ko03012,ko03029,ko03032,ko03036,ko03110,ko03400 1.A.23.1.1,3.A.12 Bacteria 2IJPT@201174,4CYVI@85004,COG3087@1,COG3087@2 NA|NA|NA D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides LPKNPDNH_00789 398513.BBNG_00181 4.3e-116 424.1 Bifidobacteriales Bacteria 2F769@1,2IFMJ@201174,33ZMP@2,4D0UD@85004 NA|NA|NA LPKNPDNH_00790 702459.BBPR_0270 4.5e-172 610.9 Bifidobacteriales Bacteria 2IBDZ@201174,4CYUA@85004,COG1520@1,COG1520@2,COG2114@1,COG2114@2 NA|NA|NA T Pfam Adenylate and Guanylate cyclase catalytic domain LPKNPDNH_00791 398513.BBNG_00184 6.1e-48 196.4 Bifidobacteriales rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904 ko:K02990 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 2IQHD@201174,4D10X@85004,COG0360@1,COG0360@2 NA|NA|NA J Binds together with S18 to 16S ribosomal RNA LPKNPDNH_00792 398513.BBNG_00185 1.1e-79 303.1 Bifidobacteriales ssb1 ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 2GMM3@201174,4CZ5V@85004,COG0629@1,COG0629@2 NA|NA|NA L Single-stranded DNA-binding protein LPKNPDNH_00793 398513.BBNG_00186 2e-36 157.9 Bifidobacteriales rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02963,ko:K03111,ko:K15125 ko03010,ko03030,ko03430,ko03440,ko05133,map03010,map03030,map03430,map03440,map05133 M00178 br01610,ko00000,ko00001,ko00002,ko00536,ko03011,ko03029,ko03032,ko03400 Bacteria 2IQ92@201174,4D103@85004,COG0238@1,COG0238@2 NA|NA|NA J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit LPKNPDNH_00794 398513.BBNG_00187 6.6e-70 270.0 Bifidobacteriales rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02939 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IKX7@201174,4D0P9@85004,COG0359@1,COG0359@2 NA|NA|NA J Binds to the 23S rRNA LPKNPDNH_00796 1437610.BREU_1938 1.9e-14 85.1 Bifidobacteriales Bacteria 2DRF9@1,2I3CM@201174,33BGI@2,4D2ZK@85004 NA|NA|NA S Parallel beta-helix repeats LPKNPDNH_00797 1437610.BREU_1938 6.5e-46 191.0 Bifidobacteriales Bacteria 2DRF9@1,2I3CM@201174,33BGI@2,4D2ZK@85004 NA|NA|NA S Parallel beta-helix repeats LPKNPDNH_00798 398513.BBNG_00189 1e-69 269.6 Actinobacteria Bacteria 2GWES@201174,COG3227@1,COG3227@2 NA|NA|NA E Domain of unknown function (DUF5011) LPKNPDNH_00800 398513.BBNG_00191 3.7e-131 474.2 Bifidobacteriales gla ko:K02440 ko00000,ko02000 1.A.8.1,1.A.8.2 iHN637.CLJU_RS07630 Bacteria 2GKK3@201174,4CZ7F@85004,COG0580@1,COG0580@2 NA|NA|NA U Belongs to the MIP aquaporin (TC 1.A.8) family LPKNPDNH_00801 398513.BBNG_00192 3.9e-129 467.6 Bifidobacteriales Bacteria 2GMJR@201174,4D0RU@85004,COG5479@1,COG5479@2 NA|NA|NA M Protein of unknown function (DUF3152) LPKNPDNH_00802 702459.BBPR_0279 5.4e-186 656.8 Bifidobacteriales gluQ 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Bacteria 2GKMT@201174,4CYRY@85004,COG0008@1,COG0008@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family LPKNPDNH_00803 398513.BBNG_00194 5e-148 530.4 Bifidobacteriales yggS ko:K06997 ko00000 Bacteria 2GMRJ@201174,4CZUY@85004,COG0325@1,COG0325@2 NA|NA|NA S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis LPKNPDNH_00804 702459.BBPR_0281 3.6e-53 214.2 Bifidobacteriales acyP GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036 Bacteria 2HZRI@201174,4D1EM@85004,COG1254@1,COG1254@2 NA|NA|NA C Acylphosphatase LPKNPDNH_00805 702459.BBPR_0282 0.0 2256.5 Bifidobacteriales inlJ ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2I2FM@201174,4CZ4I@85004,COG2304@1,COG2304@2,COG4932@1,COG4932@2 NA|NA|NA M domain protein LPKNPDNH_00806 398513.BBNG_00197 8.7e-282 975.7 Bifidobacteriales Bacteria 2GP68@201174,4CZV4@85004,COG4932@1,COG4932@2 NA|NA|NA M LPXTG cell wall anchor motif LPKNPDNH_00807 702459.BBPR_0284 7.4e-214 749.6 Bifidobacteriales 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria 2GNWT@201174,4CZMM@85004,COG3764@1,COG3764@2 NA|NA|NA M Sortase family LPKNPDNH_00808 702459.BBPR_0285 7.5e-95 354.4 Bifidobacteriales Bacteria 29W7E@1,2HZTK@201174,30HSM@2,4D1PX@85004 NA|NA|NA S Domain of unknown function (DUF4854) LPKNPDNH_00809 702459.BBPR_0286 4.2e-155 553.9 Bifidobacteriales fahA Bacteria 2GN2G@201174,4CZH5@85004,COG0179@1,COG0179@2 NA|NA|NA Q Fumarylacetoacetate (FAA) hydrolase family LPKNPDNH_00810 641146.HMPREF9020_00431 1.7e-27 129.8 Bifidobacteriales 2.1.1.72 ko:K07316 ko00000,ko01000,ko02048 Bacteria 2GN40@201174,4CZPZ@85004,COG2852@1,COG2852@2 NA|NA|NA S Protein conserved in bacteria LPKNPDNH_00811 398513.BBNG_00202 0.0 1686.0 Bifidobacteriales clpB GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 ko:K03694,ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Bacteria 2GJ73@201174,4CZDY@85004,COG0542@1,COG0542@2 NA|NA|NA O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE LPKNPDNH_00812 398513.BBNG_00203 1.6e-132 478.8 Bifidobacteriales Bacteria 2GZI1@201174,4CZ0A@85004,COG0668@1,COG0668@2 NA|NA|NA M Mechanosensitive ion channel LPKNPDNH_00813 398513.BBNG_00204 5e-119 433.7 Bifidobacteriales Bacteria 2I8SX@201174,4CZXQ@85004,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family LPKNPDNH_00814 702459.BBPR_0290 4.2e-239 833.6 Bifidobacteriales MA20_36090 Bacteria 2GMT6@201174,4CZ4Q@85004,COG1073@1,COG1073@2 NA|NA|NA S Psort location Cytoplasmic, score 8.87 LPKNPDNH_00815 398513.BBNG_00206 1.2e-232 812.0 Bifidobacteriales yhdR 2.6.1.1 ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 Bacteria 2GPM3@201174,4CZ6T@85004,COG0436@1,COG0436@2 NA|NA|NA E Psort location Cytoplasmic, score 8.87 LPKNPDNH_00816 1437608.BBIA_0377 2.6e-68 266.2 Bifidobacteriales Bacteria 2I6KG@201174,4D01Z@85004,COG5434@1,COG5434@2 NA|NA|NA M Belongs to the glycosyl hydrolase 28 family LPKNPDNH_00819 398513.BBNG_00210 2.1e-42 177.9 Bifidobacteriales Bacteria 2GQY8@201174,4D1IJ@85004,COG3311@1,COG3311@2 NA|NA|NA K Transcriptional regulator LPKNPDNH_00820 398513.BBNG_00211 0.0 1213.0 Bifidobacteriales fadD 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 2GIXQ@201174,4CYYC@85004,COG1022@1,COG1022@2 NA|NA|NA I AMP-binding enzyme LPKNPDNH_00821 68570.DC74_7007 3.5e-07 60.1 Actinobacteria ko:K21429 ko00000,ko01002 Bacteria 2GMU8@201174,COG4894@1,COG4894@2 NA|NA|NA S Scramblase LPKNPDNH_00822 398513.BBNG_00212 2e-28 131.7 Bifidobacteriales Bacteria 29W7C@1,2H1A9@201174,30HSJ@2,4D1MJ@85004 NA|NA|NA LPKNPDNH_00827 702459.BBPR_0310 3.5e-129 467.6 Bifidobacteriales tam GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0030798,GO:0032259,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0051704 2.1.1.144,2.1.1.197 ko:K00598,ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 iECABU_c1320.ECABU_c17460,iSDY_1059.SDY_1625,ic_1306.c1942 Bacteria 2GJMG@201174,4CZKQ@85004,COG4106@1,COG4106@2 NA|NA|NA S Methyltransferase domain LPKNPDNH_00828 398513.BBNG_00215 1.1e-236 825.5 Bifidobacteriales Bacteria 2IBHI@201174,4CZ2T@85004,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins LPKNPDNH_00829 398513.BBNG_00218 3.7e-54 217.2 Bifidobacteriales relB ko:K07473 ko00000,ko02048 Bacteria 2IJU2@201174,4D0WU@85004,COG3077@1,COG3077@2 NA|NA|NA L RelB antitoxin LPKNPDNH_00830 216816.GS08_01645 2.6e-17 94.4 Bifidobacteriales Bacteria 2IFQF@201174,4D0PF@85004,COG2337@1,COG2337@2 NA|NA|NA T Toxic component of a toxin-antitoxin (TA) module LPKNPDNH_00831 702459.BBPR_0316 2e-132 478.4 Bifidobacteriales Bacteria 2HZI3@201174,4D0I1@85004,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance LPKNPDNH_00832 398513.BBNG_00222 5e-243 846.7 Bifidobacteriales yxiO ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 Bacteria 2GJCW@201174,4CZU3@85004,COG2270@1,COG2270@2 NA|NA|NA S Vacuole effluxer Atg22 like LPKNPDNH_00834 398513.BBNG_00224 6.5e-201 706.4 Bifidobacteriales yegV GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 Bacteria 2IA3T@201174,4CYSM@85004,COG0524@1,COG0524@2 NA|NA|NA G pfkB family carbohydrate kinase LPKNPDNH_00835 398513.BBNG_00225 1.4e-29 134.8 Bifidobacteriales rpmB GO:0003674,GO:0003735,GO:0005198 ko:K02902 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GQNU@201174,4D17Q@85004,COG0227@1,COG0227@2 NA|NA|NA J Ribosomal L28 family LPKNPDNH_00836 702459.BBPR_0320 0.0 1664.4 Bifidobacteriales recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GKA3@201174,4CYTV@85004,COG1200@1,COG1200@2 NA|NA|NA L helicase superfamily c-terminal domain LPKNPDNH_00837 398513.BBNG_00227 4.5e-220 770.4 Bacteria steT ko:K03294 ko00000 2.A.3.2 Bacteria COG0531@1,COG0531@2 NA|NA|NA E amino acid LPKNPDNH_00840 702459.BBPR_0323 0.0 1078.2 Actinobacteria Bacteria 2EEQH@1,2IDNM@201174,338I6@2 NA|NA|NA LPKNPDNH_00841 702459.BBPR_0324 1.1e-244 852.4 Bifidobacteriales ko:K06956 ko00000 Bacteria 2GK6U@201174,4D301@85004,COG1301@1,COG1301@2 NA|NA|NA U Sodium:dicarboxylate symporter family LPKNPDNH_00842 702459.BBPR_0325 8.9e-122 443.0 Bifidobacteriales rsmD 2.1.1.171 ko:K08316 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 2GQ3G@201174,4D0GU@85004,COG0742@1,COG0742@2 NA|NA|NA L Conserved hypothetical protein 95 LPKNPDNH_00843 398513.BBNG_00232 3.1e-107 394.4 Bifidobacteriales XK27_02070 ko:K07078 ko00000 Bacteria 2H12R@201174,4D072@85004,COG3560@1,COG3560@2 NA|NA|NA S Nitroreductase family LPKNPDNH_00844 702459.BBPR_0327 8.9e-83 312.8 Bifidobacteriales hsp20 ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 2HZHR@201174,4D0H9@85004,COG0071@1,COG0071@2 NA|NA|NA O Hsp20/alpha crystallin family LPKNPDNH_00845 398513.BBNG_00234 1.4e-165 589.0 Bifidobacteriales trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 ko:K00554,ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 2GJ1G@201174,4CZ7A@85004,COG0336@1,COG0336@2 NA|NA|NA J Belongs to the RNA methyltransferase TrmD family LPKNPDNH_00846 398513.BBNG_00235 1.3e-108 399.1 Bifidobacteriales rimM GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 ko:K02860 ko00000,ko03009 Bacteria 2GK4I@201174,4D0C6@85004,COG0806@1,COG0806@2 NA|NA|NA J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes LPKNPDNH_00847 398513.BBNG_00236 8.8e-34 149.1 Bifidobacteriales CP_0960 GO:0008150,GO:0040007 ko:K06960 ko00000 Bacteria 2IQ4C@201174,4D16Z@85004,COG1837@1,COG1837@2 NA|NA|NA S Belongs to the UPF0109 family LPKNPDNH_00848 398513.BBNG_00237 1e-54 219.5 Bifidobacteriales rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02959 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 2IKU0@201174,4D0PE@85004,COG0228@1,COG0228@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS16 family LPKNPDNH_00849 702459.BBPR_0332 2.5e-294 1017.3 Bifidobacteriales ydfD ko:K18907 M00700,M00702 ko00000,ko00002,ko01504,ko03000 Bacteria 2GITW@201174,4CZGJ@85004,COG1167@1,COG1167@2 NA|NA|NA EK Alanine-glyoxylate amino-transferase LPKNPDNH_00850 398513.BBNG_00240 5.9e-94 350.5 Bifidobacteriales argO GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015181,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902023,GO:1903825,GO:1903826,GO:1905039,GO:1990822 ko:K06895 ko00000,ko02000 2.A.75.1 iPC815.YPO0918 Bacteria 2HZBK@201174,4CZJP@85004,COG1279@1,COG1279@2 NA|NA|NA S LysE type translocator LPKNPDNH_00851 702459.BBPR_0334 1.5e-219 768.5 Bifidobacteriales Bacteria 2GK2H@201174,4CYS3@85004,COG3021@1,COG3021@2 NA|NA|NA S Endonuclease/Exonuclease/phosphatase family LPKNPDNH_00852 398513.BBNG_00242 1.3e-269 935.3 Bifidobacteriales ffh GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 Bacteria 2GK4R@201174,4CYY1@85004,COG0541@1,COG0541@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY LPKNPDNH_00853 398513.BBNG_00244 1.4e-164 585.5 Bifidobacteriales Bacteria 2H4CC@201174,4CZ1H@85004,COG3965@1,COG3965@2 NA|NA|NA P Cation efflux family LPKNPDNH_00854 398513.BBNG_00246 0.0 1078.9 Bifidobacteriales cysS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GJF2@201174,4CZZ9@85004,COG0215@1,COG0215@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family LPKNPDNH_00855 398513.BBNG_00247 2.3e-136 491.5 Bifidobacteriales guaA1 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 2GNA6@201174,4CYR4@85004,COG0518@1,COG0518@2 NA|NA|NA F Peptidase C26 LPKNPDNH_00856 398513.BBNG_00248 0.0 1350.5 Bifidobacteriales yjjK ko:K15738 ko00000,ko02000 3.A.1.120.6 Bacteria 2GJ5M@201174,4CZCU@85004,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter LPKNPDNH_00857 398513.BBNG_00249 2e-58 231.5 Bifidobacteriales Bacteria 2CAFG@1,2I800@201174,32ZDZ@2,4D107@85004 NA|NA|NA S Protein of unknown function (DUF3039) LPKNPDNH_00858 702459.BBPR_0342 2.4e-89 334.7 Bifidobacteriales coaD 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN1S@201174,4CYR5@85004,COG0669@1,COG0669@2 NA|NA|NA H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate LPKNPDNH_00859 702459.BBPR_0343 3.6e-107 394.8 Bifidobacteriales Bacteria 2EKTZ@1,2HZD3@201174,33EHP@2,4CZV9@85004 NA|NA|NA LPKNPDNH_00860 398513.BBNG_00252 5.1e-113 413.7 Bifidobacteriales yceD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 ko:K07040 ko00000 Bacteria 2GJTS@201174,4CZ0J@85004,COG1399@1,COG1399@2 NA|NA|NA S Uncharacterized ACR, COG1399 LPKNPDNH_00861 398513.BBNG_00253 2.3e-19 100.9 Bifidobacteriales rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 ko:K02911 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 2GQP3@201174,4D18N@85004,COG0333@1,COG0333@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL32 family LPKNPDNH_00862 398513.BBNG_00254 6.1e-140 503.4 Bifidobacteriales rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Bacteria 2GKER@201174,4CZ98@85004,COG0571@1,COG0571@2 NA|NA|NA J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism LPKNPDNH_00863 702459.BBPR_0347 0.0 1276.9 Bifidobacteriales ilvB 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKU4@201174,4CYR0@85004,COG0028@1,COG0028@2 NA|NA|NA H Thiamine pyrophosphate enzyme, central domain LPKNPDNH_00864 398513.BBNG_00256 7.6e-92 343.2 Bifidobacteriales ilvN GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 iECO103_1326.ilvN,iJN678.ilvN Bacteria 2GJCH@201174,4CYXX@85004,COG0440@1,COG0440@2 NA|NA|NA E ACT domain LPKNPDNH_00866 398513.BBNG_00259 7.5e-247 859.4 Bifidobacteriales pncB GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0030312,GO:0034355,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 R01724 RC00033 ko00000,ko00001,ko01000 Bacteria 2GJAT@201174,4CYUR@85004,COG1488@1,COG1488@2 NA|NA|NA F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP LPKNPDNH_00867 398513.BBNG_00260 2.1e-134 485.0 Bifidobacteriales rph GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56,3.6.1.66 ko:K00989,ko:K02428 ko00230,map00230 R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000,ko03016 Bacteria 2GJFI@201174,4CZBF@85004,COG0689@1,COG0689@2 NA|NA|NA J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates LPKNPDNH_00868 398513.BBNG_00261 1.7e-117 428.7 Bifidobacteriales rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 Bacteria 2GM2B@201174,4CZ3F@85004,COG0127@1,COG0127@2 NA|NA|NA F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions LPKNPDNH_00869 398513.BBNG_00262 2.4e-176 624.8 Bifidobacteriales ko:K07088 ko00000 Bacteria 2GN0R@201174,4CZ6C@85004,COG0679@1,COG0679@2 NA|NA|NA S Auxin Efflux Carrier LPKNPDNH_00872 398513.BBNG_00263 0.0 1144.0 Bifidobacteriales pgi GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GJG0@201174,4CYVV@85004,COG0166@1,COG0166@2 NA|NA|NA G Belongs to the GPI family LPKNPDNH_00873 398513.BBNG_00264 1.5e-190 672.2 Bifidobacteriales Bacteria 2ASZC@1,2IHXX@201174,31IF2@2,4D0YI@85004 NA|NA|NA LPKNPDNH_00875 398513.BBNG_00267 6.9e-201 706.4 Bifidobacteriales Bacteria 2ASZC@1,2H9FD@201174,30V61@2,4D2GH@85004 NA|NA|NA LPKNPDNH_00877 398513.BBNG_00269 1.6e-83 315.5 Bifidobacteriales mgtC ko:K07507 ko00000,ko02000 9.B.20 Bacteria 2GJF0@201174,4D0N8@85004,COG1285@1,COG1285@2 NA|NA|NA S MgtC family LPKNPDNH_00878 702459.BBPR_0359 8.2e-28 129.4 Bifidobacteriales mgtC ko:K07507 ko00000,ko02000 9.B.20 Bacteria 2GJF0@201174,4D0N8@85004,COG1285@1,COG1285@2 NA|NA|NA S MgtC family LPKNPDNH_00879 702459.BBPR_0360 0.0 1382.1 Bifidobacteriales mgtA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0099131,GO:0099132 3.6.3.2 ko:K01531,ko:K01992,ko:K16905 ko02010,map02010 M00224,M00254 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.3.4 iSF_1195.SF4248 Bacteria 2GJJC@201174,4CZMI@85004,COG0474@1,COG0474@2 NA|NA|NA P Cation transporting ATPase, C-terminus LPKNPDNH_00880 398513.BBNG_00270 9.7e-34 149.4 Bifidobacteriales mgtA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0099131,GO:0099132 3.6.3.2 ko:K01531,ko:K01992,ko:K16905 ko02010,map02010 M00224,M00254 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.3.4 iSF_1195.SF4248 Bacteria 2GJJC@201174,4CZMI@85004,COG0474@1,COG0474@2 NA|NA|NA P Cation transporting ATPase, C-terminus LPKNPDNH_00881 398513.BBNG_00270 2.4e-24 117.5 Bifidobacteriales mgtA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0099131,GO:0099132 3.6.3.2 ko:K01531,ko:K01992,ko:K16905 ko02010,map02010 M00224,M00254 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.3.4 iSF_1195.SF4248 Bacteria 2GJJC@201174,4CZMI@85004,COG0474@1,COG0474@2 NA|NA|NA P Cation transporting ATPase, C-terminus LPKNPDNH_00882 398513.BBNG_00271 3.5e-277 960.3 Bifidobacteriales abcT3 ko:K02049 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 2GN33@201174,4D00C@85004,COG1116@1,COG1116@2,COG4754@1,COG4754@2 NA|NA|NA P ATPases associated with a variety of cellular activities LPKNPDNH_00883 702459.BBPR_0363 0.0 1146.7 Bifidobacteriales opuAB ko:K02050 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 2GNF7@201174,4CZJS@85004,COG4986@1,COG4986@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component LPKNPDNH_00885 398513.BBNG_00274 1.4e-173 615.5 Bifidobacteriales Bacteria 2GMIM@201174,4D05F@85004,COG2390@1,COG2390@2 NA|NA|NA K Putative sugar-binding domain LPKNPDNH_00886 702459.BBPR_0366 3.4e-212 744.2 Bifidobacteriales gatC ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.5.1 Bacteria 2IBG5@201174,4D0NN@85004,COG3775@1,COG3775@2 NA|NA|NA G PTS system sugar-specific permease component LPKNPDNH_00887 702459.BBPR_0367 8e-293 1012.3 Bifidobacteriales 2.7.1.53 ko:K00880 ko00040,ko00053,map00040,map00053 R01901,R07127 RC00002,RC00017,RC00538 ko00000,ko00001,ko01000 Bacteria 2HFYG@201174,4D0I3@85004,COG1070@1,COG1070@2 NA|NA|NA G FGGY family of carbohydrate kinases, C-terminal domain LPKNPDNH_00888 702459.BBPR_0368 1.1e-172 612.5 Bifidobacteriales ulaE GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019324,GO:0019752,GO:0019852,GO:0034015,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0051186,GO:0071704 5.1.3.22 ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 M00550 R03244 RC00540 ko00000,ko00001,ko00002,ko01000 iEC55989_1330.EC55989_4754,iECSE_1348.ECSE_4495,iEcHS_1320.EcHS_A4441,iEcSMS35_1347.EcSMS35_4668,iYL1228.KPN_04590 Bacteria 2GQYR@201174,4D0CH@85004,COG3623@1,COG3623@2 NA|NA|NA G Xylose isomerase-like TIM barrel LPKNPDNH_00889 398513.BBNG_00278 1.1e-129 469.2 Bifidobacteriales araD 4.1.2.17,5.1.3.4 ko:K01628,ko:K03077 ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120 M00550 R02262,R05850 RC00603,RC00604,RC01479 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNI6@201174,4CZXX@85004,COG0235@1,COG0235@2 NA|NA|NA G Class II Aldolase and Adducin N-terminal domain LPKNPDNH_00890 398513.BBNG_00279 5.6e-62 243.4 Bifidobacteriales rplS GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02884 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHRT@201174,4D0V2@85004,COG0335@1,COG0335@2 NA|NA|NA J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site LPKNPDNH_00891 702459.BBPR_0371 6.8e-158 563.1 Bifidobacteriales lepB GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 2GIYN@201174,4CZEY@85004,COG0681@1,COG0681@2 NA|NA|NA U Belongs to the peptidase S26 family LPKNPDNH_00892 702459.BBPR_0372 7.2e-132 476.5 Bifidobacteriales rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 2GJFN@201174,4CZ1U@85004,COG0164@1,COG0164@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids LPKNPDNH_00893 398513.BBNG_00282 2.9e-207 727.6 Bifidobacteriales ko:K02529 ko00000,ko03000 Bacteria 2GK1X@201174,4CYR6@85004,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor LPKNPDNH_00894 702459.BBPR_0374 0.0 1263.4 Bifidobacteriales fadD 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 2GIXQ@201174,4CZZP@85004,COG1022@1,COG1022@2 NA|NA|NA I AMP-binding enzyme LPKNPDNH_00895 398513.BBNG_00285 1.5e-155 555.4 Bifidobacteriales pdxS GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 ko:K06215 ko00750,map00750 R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 Bacteria 2GK1T@201174,4CZ5P@85004,COG0214@1,COG0214@2 NA|NA|NA H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively LPKNPDNH_00896 398513.BBNG_00286 1.1e-110 406.0 Bifidobacteriales pdxT GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 ko:K08681 ko00750,map00750 R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 iHN637.CLJU_RS19495 Bacteria 2GNYG@201174,4CYUS@85004,COG0311@1,COG0311@2 NA|NA|NA H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS LPKNPDNH_00899 398513.BBNG_00288 6.1e-172 610.1 Bifidobacteriales Bacteria 2I2H2@201174,4CZDP@85004,COG3507@1,COG3507@2 NA|NA|NA G Glycosyl hydrolases family 43 LPKNPDNH_00900 702459.BBPR_0379 9.2e-106 389.4 Bifidobacteriales Bacteria 2I2H2@201174,4CZDP@85004,COG3507@1,COG3507@2 NA|NA|NA G Glycosyl hydrolases family 43 LPKNPDNH_00901 702459.BBPR_0381 5.9e-203 713.4 Bifidobacteriales Bacteria 2GJ5Q@201174,4D040@85004,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor LPKNPDNH_00902 702459.BBPR_0382 2.9e-170 604.4 Bifidobacteriales dkgA GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008106,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0055114,GO:0071704,GO:1901575 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 iECH74115_1262.ECH74115_4323,iECSP_1301.ECSP_3988 Bacteria 2GJQ7@201174,4CYUN@85004,COG0656@1,COG0656@2 NA|NA|NA S Oxidoreductase, aldo keto reductase family protein LPKNPDNH_00903 398513.BBNG_00293 2.1e-134 485.0 Bifidobacteriales Bacteria 2GJ38@201174,4CZCY@85004,COG2356@1,COG2356@2 NA|NA|NA L Protein of unknown function (DUF1524) LPKNPDNH_00904 702459.BBPR_0384 1.4e-224 785.4 Bifidobacteriales mntH GO:0000041,GO:0003674,GO:0005215,GO:0005384,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0008324,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015075,GO:0015077,GO:0015078,GO:0015086,GO:0015291,GO:0015292,GO:0015293,GO:0015318,GO:0015672,GO:0015684,GO:0015691,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0034755,GO:0042221,GO:0044425,GO:0044464,GO:0046873,GO:0046915,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070574,GO:0070838,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071421,GO:0071577,GO:0071578,GO:0071944,GO:0072511,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098739,GO:0099587,GO:1902600 ko:K03322 ko00000,ko02000 2.A.55.2.6,2.A.55.3 iSF_1195.SF2457,iYO844.BSU04360 Bacteria 2GJSM@201174,4CZZB@85004,COG1914@1,COG1914@2 NA|NA|NA P H( )-stimulated, divalent metal cation uptake system LPKNPDNH_00905 326426.Bbr_0428 3.9e-250 870.5 Bifidobacteriales Bacteria 2GIZX@201174,4CZWX@85004,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily LPKNPDNH_00906 1437608.BBIA_0616 9.9e-172 609.8 Bifidobacteriales Bacteria 2GMZX@201174,4D0DN@85004,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives IS30 family LPKNPDNH_00907 78344.BIGA_0864 4.4e-103 381.7 Actinobacteria Bacteria 2GJJJ@201174,COG1316@1,COG1316@2 NA|NA|NA K cell envelope-related transcriptional attenuator LPKNPDNH_00908 398513.BBNG_00296 3.2e-212 744.6 Bifidobacteriales Bacteria 2DDMI@1,2ICIR@201174,2ZIJN@2,4D00F@85004 NA|NA|NA LPKNPDNH_00909 702459.BBPR_0387 1.3e-179 635.6 Bifidobacteriales Bacteria 2I2GH@201174,4CYVC@85004,COG3583@1,COG3583@2 NA|NA|NA S G5 LPKNPDNH_00910 702459.BBPR_0388 1.5e-59 235.3 Bifidobacteriales trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.8,1.8.1.9 ko:K00384,ko:K03671,ko:K03672 ko00450,ko04621,ko05418,map00450,map04621,map05418 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000,ko03110 Bacteria 2IKP1@201174,4D11J@85004,COG0526@1,COG0526@2 NA|NA|NA O Belongs to the thioredoxin family LPKNPDNH_00911 702459.BBPR_0389 4.8e-119 433.7 Bifidobacteriales Bacteria 2GJGZ@201174,4CYT1@85004,COG1051@1,COG1051@2 NA|NA|NA F Domain of unknown function (DUF4916) LPKNPDNH_00912 398513.BBNG_00300 2.6e-160 571.2 Bifidobacteriales mhpC Bacteria 2I2GI@201174,4CYXW@85004,COG2267@1,COG2267@2 NA|NA|NA I Alpha/beta hydrolase family LPKNPDNH_00913 398513.BBNG_00301 2.4e-08 63.2 Bifidobacteriales nudC GO:0003674,GO:0003824,GO:0004551,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0033554,GO:0034641,GO:0035529,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 1.3.7.1,3.6.1.22 ko:K03426,ko:K20449 ko00760,ko01100,ko01120,ko04146,map00760,map01100,map01120,map04146 R00103,R03004,R03164,R11104 RC00002,RC02422 ko00000,ko00001,ko01000 iAF1260.b3996,iB21_1397.B21_03826,iBWG_1329.BWG_3656,iEC55989_1330.EC55989_4481,iECBD_1354.ECBD_4036,iECB_1328.ECB_03873,iECDH10B_1368.ECDH10B_4185,iECDH1ME8569_1439.ECDH1ME8569_3856,iECD_1391.ECD_03873,iECIAI1_1343.ECIAI1_4211,iECO103_1326.ECO103_4745,iECO111_1330.ECO111_4813,iECO26_1355.ECO26_5105,iECSE_1348.ECSE_4284,iECW_1372.ECW_m4355,iEKO11_1354.EKO11_4325,iETEC_1333.ETEC_4256,iEcDH1_1363.EcDH1_3998,iEcE24377_1341.EcE24377A_4539,iEcHS_1320.EcHS_A4230,iEcolC_1368.EcolC_4029,iJO1366.b3996,iPC815.YPO3736,iSSON_1240.SSON_4169,iUMNK88_1353.UMNK88_4837,iWFL_1372.ECW_m4355,iY75_1357.Y75_RS17065,iYL1228.KPN_04378 Bacteria 2GJZY@201174,4CZE5@85004,COG2816@1,COG2816@2 NA|NA|NA L NADH pyrophosphatase zinc ribbon domain LPKNPDNH_00914 398513.BBNG_00302 0.0 1152.5 Bifidobacteriales enhA_2 Bacteria 2GQ7D@201174,4CZ5A@85004,COG1376@1,COG1376@2 NA|NA|NA S L,D-transpeptidase catalytic domain LPKNPDNH_00915 398513.BBNG_00303 3.7e-72 277.3 Bifidobacteriales gcvH ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 Bacteria 2IKN2@201174,4D0W7@85004,COG0509@1,COG0509@2 NA|NA|NA E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein LPKNPDNH_00916 398513.BBNG_00304 9.2e-201 706.1 Bifidobacteriales Bacteria 2GKPS@201174,4CZ13@85004,COG4850@1,COG4850@2 NA|NA|NA S Uncharacterized conserved protein (DUF2183) LPKNPDNH_00917 398513.BBNG_00304 5.1e-27 126.3 Bifidobacteriales Bacteria 2GKPS@201174,4CZ13@85004,COG4850@1,COG4850@2 NA|NA|NA S Uncharacterized conserved protein (DUF2183) LPKNPDNH_00918 702459.BBPR_0395 0.0 1691.0 Bifidobacteriales ptrB 3.4.21.83 ko:K01354 ko05142,ko05143,map05142,map05143 ko00000,ko00001,ko01000,ko01002 Bacteria 2GNA9@201174,4CZ2X@85004,COG1770@1,COG1770@2 NA|NA|NA E Peptidase, S9A B C family, catalytic domain protein LPKNPDNH_00919 398513.BBNG_00306 4.5e-191 673.7 Bifidobacteriales leuB 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GK44@201174,4CZ08@85004,COG0473@1,COG0473@2 NA|NA|NA CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate LPKNPDNH_00920 702459.BBPR_0399 7.6e-236 822.8 Bifidobacteriales lplA 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 Bacteria 2GJV5@201174,4CZYA@85004,COG0095@1,COG0095@2 NA|NA|NA H Biotin/lipoate A/B protein ligase family LPKNPDNH_00921 398513.BBNG_00308 1.6e-134 485.3 Bifidobacteriales glxR GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 Bacteria 2GMPN@201174,4CYYW@85004,COG0664@1,COG0664@2 NA|NA|NA K helix_turn_helix, cAMP Regulatory protein LPKNPDNH_00922 702459.BBPR_0401 0.0 1396.3 Bifidobacteriales pon1 2.4.1.129,3.4.16.4 ko:K05365,ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 2GK21@201174,4CZAZ@85004,COG0744@1,COG0744@2 NA|NA|NA M Transglycosylase LPKNPDNH_00923 702459.BBPR_0403 1.1e-217 762.3 Bifidobacteriales namA 1.6.99.1 ko:K00354 R00282 RC00001 ko00000,ko01000 Bacteria 2GK8E@201174,4CZ9Z@85004,COG1902@1,COG1902@2 NA|NA|NA C NADH:flavin oxidoreductase / NADH oxidase family LPKNPDNH_00924 398513.BBNG_00312 5.7e-227 793.1 Bifidobacteriales pyrD 1.3.1.14,1.3.5.2,1.3.98.1 ko:K00226,ko:K00254,ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01868,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKC6@201174,4CYWW@85004,COG0167@1,COG0167@2 NA|NA|NA F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor LPKNPDNH_00925 398513.BBNG_00313 8e-144 516.5 Bifidobacteriales glpR ko:K02444 ko00000,ko03000 Bacteria 2H5X4@201174,4CZMT@85004,COG1349@1,COG1349@2 NA|NA|NA K DeoR C terminal sensor domain LPKNPDNH_00926 702459.BBPR_0406 3.3e-252 877.1 Bifidobacteriales galT 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2I2DM@201174,4CYXZ@85004,COG1085@1,COG1085@2 NA|NA|NA C Galactose-1-phosphate uridyl transferase, N-terminal domain LPKNPDNH_00927 398513.BBNG_00315 9.9e-233 812.4 Bifidobacteriales galK 2.7.1.6,2.7.7.12 ko:K00849,ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955,R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GJXI@201174,4CZNV@85004,COG0153@1,COG0153@2 NA|NA|NA G Belongs to the GHMP kinase family. GalK subfamily LPKNPDNH_00928 702459.BBPR_0408 8.6e-243 845.9 Bifidobacteriales Bacteria 2GIYR@201174,4CZFF@85004,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter LPKNPDNH_00929 398513.BBNG_00318 4.2e-43 180.3 Bifidobacteriales gcvR ko:K07166 ko00000 Bacteria 2IKS1@201174,4D11D@85004,COG3830@1,COG3830@2 NA|NA|NA T Belongs to the UPF0237 family LPKNPDNH_00930 702459.BBPR_0411 4.7e-252 876.7 Bifidobacteriales ko:K09157 ko00000 Bacteria 2HHMF@201174,4CZGB@85004,COG2848@1,COG2848@2 NA|NA|NA S UPF0210 protein LPKNPDNH_00931 398513.BBNG_00321 2.5e-72 278.1 Bacteria Bacteria COG5305@1,COG5305@2 NA|NA|NA LPKNPDNH_00933 398513.BBNG_00323 6.3e-122 443.4 Bifidobacteriales trmL GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 ko:K03216 ko00000,ko01000,ko03016 Bacteria 2IHN9@201174,4CZ0E@85004,COG0219@1,COG0219@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily LPKNPDNH_00934 33035.JPJF01000013_gene4535 6.7e-68 264.2 Blautia exsH 3.2.1.178,3.2.1.18,3.2.1.52 ko:K01186,ko:K02316,ko:K12373,ko:K20830 ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko03030,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map03030,map04142 M00079 R00022,R04018,R06004,R11316 RC00028,RC00049,RC00077 ko00000,ko00001,ko00002,ko01000,ko02042,ko03032,ko03110 GH16,GH20,GH33 Bacteria 1UUUJ@1239,25KCI@186801,3Y1HA@572511,COG1196@1,COG1196@2,COG2273@1,COG2273@2,COG5263@1,COG5263@2 NA|NA|NA G Putative cell wall binding repeat LPKNPDNH_00935 398513.BBNG_00325 2.5e-185 655.2 Bifidobacteriales mutY 2.1.1.37,2.1.3.15,6.4.1.2 ko:K00558,ko:K01962,ko:K01963,ko:K03575 ko00061,ko00270,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03410,ko05206,map00061,map00270,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212,map03410,map05206 M00035,M00082,M00376 R00742,R04386,R04858 RC00003,RC00040,RC00253,RC00332,RC00367 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 2GJD9@201174,4CYRB@85004,COG1194@1,COG1194@2 NA|NA|NA L FES LPKNPDNH_00936 702459.BBPR_0417 7.6e-107 393.3 Bifidobacteriales Bacteria 2E5CN@1,2I2GJ@201174,3304R@2,4D0SD@85004 NA|NA|NA LPKNPDNH_00937 702459.BBPR_0418 0.0 2417.9 Bifidobacteriales rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2GJ81@201174,4CZ3W@85004,COG0085@1,COG0085@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates LPKNPDNH_00938 702459.BBPR_0419 0.0 2540.0 Bifidobacteriales rpoC GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2GKWF@201174,4CZ1D@85004,COG0086@1,COG0086@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates LPKNPDNH_00939 398513.BBNG_00329 7.2e-95 353.2 Bifidobacteriales Bacteria 2IIXF@201174,4D0UU@85004,COG1716@1,COG1716@2 NA|NA|NA T Forkhead associated domain LPKNPDNH_00940 702459.BBPR_0421 2.8e-68 265.0 Bifidobacteriales Bacteria 2GRHT@201174,4D0W6@85004,COG5602@1,COG5602@2 NA|NA|NA B Belongs to the OprB family LPKNPDNH_00941 702459.BBPR_0422 3.7e-165 587.4 Bifidobacteriales 3.1.3.16 ko:K01090,ko:K20074 ko00000,ko01000,ko01009 Bacteria 2GJ3M@201174,4CZNH@85004,COG0631@1,COG0631@2 NA|NA|NA T Sigma factor PP2C-like phosphatases LPKNPDNH_00942 702459.BBPR_0423 0.0 1588.9 Bifidobacteriales Bacteria 2HQBB@201174,4CZ3X@85004,COG1305@1,COG1305@2 NA|NA|NA E Transglutaminase-like superfamily LPKNPDNH_00943 702459.BBPR_0424 5.7e-231 806.6 Bifidobacteriales Bacteria 2GIWE@201174,4CZWT@85004,COG1721@1,COG1721@2 NA|NA|NA S Protein of unknown function DUF58 LPKNPDNH_00944 702459.BBPR_0425 1.8e-232 812.0 Bifidobacteriales ko:K03924 ko00000,ko01000 Bacteria 2GK07@201174,4CZ3M@85004,COG0714@1,COG0714@2 NA|NA|NA S ATPase family associated with various cellular activities (AAA) LPKNPDNH_00945 398513.BBNG_00335 0.0 3726.8 Bifidobacteriales ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 2GMKC@201174,4CZFT@85004,COG4733@1,COG4733@2 NA|NA|NA S Fibronectin type 3 domain LPKNPDNH_00946 702459.BBPR_0427 3.4e-269 933.7 Bifidobacteriales Bacteria 2GIW5@201174,4CZ9N@85004,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase LPKNPDNH_00947 702459.BBPR_0428 0.0 2803.9 Bifidobacteriales uvrD 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJD0@201174,4CYQU@85004,COG0210@1,COG0210@2,COG2887@1,COG2887@2 NA|NA|NA L PD-(D/E)XK nuclease superfamily LPKNPDNH_00948 702459.BBPR_0429 0.0 2731.4 Bifidobacteriales uvrD2 3.6.4.12 ko:K03657,ko:K07465 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GM2E@201174,4CZ49@85004,COG0210@1,COG0210@2,COG2887@1,COG2887@2 NA|NA|NA L Belongs to the helicase family. UvrD subfamily LPKNPDNH_00949 702459.BBPR_0430 3.4e-147 527.7 Bifidobacteriales Bacteria 2IKFK@201174,4D0XC@85004,COG0454@1,COG0454@2 NA|NA|NA K -acetyltransferase LPKNPDNH_00950 702459.BBPR_0431 3.8e-249 867.1 Bifidobacteriales Bacteria 2I2GK@201174,4CZ0T@85004,COG2271@1,COG2271@2 NA|NA|NA G Major Facilitator Superfamily LPKNPDNH_00951 398513.BBNG_00342 6.5e-43 179.5 Bifidobacteriales 2.1.1.72 ko:K03497,ko:K07316 ko00000,ko01000,ko02048,ko03000,ko03036,ko04812 Bacteria 2GNZR@201174,4D1DE@85004,COG0863@1,COG0863@2 NA|NA|NA L Belongs to the N(4) N(6)-methyltransferase family LPKNPDNH_00952 398513.BBNG_00343 6.4e-24 115.9 Bifidobacteriales relB ko:K07473 ko00000,ko02048 Bacteria 2GRBT@201174,4D1GU@85004,COG3077@1,COG3077@2 NA|NA|NA L RelB antitoxin LPKNPDNH_00953 702459.BBPR_0434 5.5e-35 152.9 Bifidobacteriales Bacteria 2IF22@201174,4D0MK@85004,COG3677@1,COG3677@2 NA|NA|NA L Transposase LPKNPDNH_00954 398513.BBNG_00345 1e-132 479.6 Bifidobacteriales dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 iJN678.dapB,iYO844.BSU22490 Bacteria 2GM2T@201174,4CZJ5@85004,COG0289@1,COG0289@2 NA|NA|NA E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate LPKNPDNH_00955 398513.BBNG_00346 2.8e-45 187.6 Bifidobacteriales dapA 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ34@201174,4CZ34@85004,COG0329@1,COG0329@2 NA|NA|NA E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) LPKNPDNH_00956 702459.BBPR_0436 2.2e-102 378.3 Bifidobacteriales dapA 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ34@201174,4CZ34@85004,COG0329@1,COG0329@2 NA|NA|NA E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) LPKNPDNH_00957 398513.BBNG_00347 0.0 1176.8 Bifidobacteriales rnj GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 2GIW7@201174,4CZEJ@85004,COG0595@1,COG0595@2 NA|NA|NA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay LPKNPDNH_00958 398513.BBNG_00348 0.0 1763.0 Bifidobacteriales pepN 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 2GJJ4@201174,4CZH4@85004,COG0308@1,COG0308@2 NA|NA|NA E Peptidase family M1 domain LPKNPDNH_00959 398513.BBNG_00349 4.8e-291 1006.5 Bifidobacteriales ko:K14645 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Bacteria 2GMBS@201174,4CZY0@85004,COG1404@1,COG1404@2 NA|NA|NA O Subtilase family LPKNPDNH_00960 398513.BBNG_00351 2.1e-255 887.9 Bifidobacteriales glmM GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 R02060 RC00408 ko00000,ko00001,ko01000 iAF987.Gmet_1886,iLJ478.TM0184,iSB619.SA_RS11275,iSBO_1134.SBO_3206 Bacteria 2GN87@201174,4CYZX@85004,COG1109@1,COG1109@2 NA|NA|NA G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate LPKNPDNH_00961 398513.BBNG_00352 8.8e-124 449.5 Bifidobacteriales def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 ko00000,ko01000 Bacteria 2GNZ9@201174,4CZ7M@85004,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions LPKNPDNH_00962 702459.BBPR_0443 1.4e-270 938.3 Bifidobacteriales Bacteria 2GJ39@201174,4CZC0@85004,COG4279@1,COG4279@2 NA|NA|NA S zinc finger LPKNPDNH_00963 702459.BBPR_0444 4.1e-105 387.5 Bifidobacteriales vsr ko:K07458 ko00000,ko01000,ko03400 Bacteria 2IKPY@201174,4D0R6@85004,COG3727@1,COG3727@2 NA|NA|NA L May nick specific sequences that contain T G mispairs resulting from m5C-deamination LPKNPDNH_00964 398513.BBNG_00355 2.9e-229 800.8 Bifidobacteriales aspB Bacteria 2GJ7R@201174,4CZQP@85004,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase class-V LPKNPDNH_00965 762211.BSTEL_2045 9e-157 559.7 Bifidobacteriales ppx GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 2GMME@201174,4CYW8@85004,COG0248@1,COG0248@2 NA|NA|NA FP Ppx/GppA phosphatase family LPKNPDNH_00966 398513.BBNG_00357 3.5e-132 477.6 Bifidobacteriales tmp1 Bacteria 28XY7@1,2GN31@201174,2ZJU4@2,4CZQG@85004 NA|NA|NA S Domain of unknown function (DUF4391) LPKNPDNH_00967 702459.BBPR_0448 4.4e-149 533.9 Bifidobacteriales moeB 2.7.7.80 ko:K21029 ko04122,map04122 R07459 RC00043 ko00000,ko00001,ko01000 Bacteria 2GJB6@201174,4D06G@85004,COG0476@1,COG0476@2 NA|NA|NA H ThiF family LPKNPDNH_00968 702459.BBPR_0449 1.3e-254 885.2 Bifidobacteriales cdr GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 ko:K04085 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Bacteria 2I65D@201174,4D0GG@85004,COG0425@1,COG0425@2,COG0607@1,COG0607@2,COG2210@1,COG2210@2 NA|NA|NA OP Sulfurtransferase TusA LPKNPDNH_00969 398513.BBNG_00360 3.1e-181 641.0 Bifidobacteriales iunH1 3.2.2.1 ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 Bacteria 2GP6N@201174,4CZ0Y@85004,COG1957@1,COG1957@2 NA|NA|NA F Inosine-uridine preferring nucleoside hydrolase LPKNPDNH_00972 398513.BBNG_00363 9.6e-203 712.6 Bifidobacteriales ko:K18353 ko01502,ko02020,map01502,map02020 M00651 ko00000,ko00001,ko00002,ko01504 Bacteria 2I2GX@201174,4CYTX@85004,COG3568@1,COG3568@2 NA|NA|NA S Endonuclease/Exonuclease/phosphatase family LPKNPDNH_00973 398513.BBNG_00364 7.8e-43 179.5 Bifidobacteriales xseB GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GR0U@201174,4D18C@85004,COG1722@1,COG1722@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides LPKNPDNH_00974 702459.BBPR_0454 3.6e-271 940.3 Bifidobacteriales xseA GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.1.11.6 ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJAS@201174,4CZU4@85004,COG1570@1,COG1570@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides LPKNPDNH_00975 398513.BBNG_00366 0.0 1647.9 Bifidobacteriales nrdD GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0017076,GO:0018130,GO:0019001,GO:0019103,GO:0019438,GO:0019637,GO:0019692,GO:0030554,GO:0031250,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032556,GO:0032558,GO:0032559,GO:0032560,GO:0032564,GO:0032567,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0046872,GO:0046914,GO:0051065,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_4713,iPC815.YPO3454 Bacteria 2GMGA@201174,4CYV3@85004,COG1328@1,COG1328@2 NA|NA|NA F Anaerobic ribonucleoside-triphosphate reductase LPKNPDNH_00976 398513.BBNG_00367 2.5e-140 504.6 Bifidobacteriales nrdG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0031250,GO:0032991,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 1.97.1.4 ko:K04068 R04710 ko00000,ko01000 iE2348C_1286.E2348C_4563 Bacteria 2H0HA@201174,4CYSC@85004,COG0602@1,COG0602@2 NA|NA|NA O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine LPKNPDNH_00978 398513.BBNG_00369 0.0 3256.1 Bifidobacteriales hgdC Bacteria 2I1VH@201174,4CZ6Y@85004,COG1924@1,COG1924@2,COG3580@1,COG3580@2,COG3581@1,COG3581@2 NA|NA|NA I CoA enzyme activase uncharacterised domain (DUF2229) LPKNPDNH_00979 702459.BBPR_0458 1.2e-166 592.4 Actinobacteria Bacteria 28NJG@1,2GT1B@201174,30HV1@2 NA|NA|NA LPKNPDNH_00980 398513.BBNG_00371 1.9e-259 901.4 Bifidobacteriales gshA 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJPI@201174,4CYZP@85004,COG3572@1,COG3572@2 NA|NA|NA H Glutamate-cysteine ligase family 2(GCS2) LPKNPDNH_00981 398513.BBNG_00372 0.0 2566.6 Bifidobacteriales plyA3 3.2.1.18 ko:K01186,ko:K12547 ko00511,ko00600,ko04142,map00511,map00600,map04142 R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 GH33 Bacteria 2I2HT@201174,4D0IE@85004,COG3064@1,COG3064@2,COG5434@1,COG5434@2 NA|NA|NA M Parallel beta-helix repeats LPKNPDNH_00982 398513.BBNG_00373 1.7e-88 332.0 Bifidobacteriales Bacteria 2IIWT@201174,4D0WT@85004,COG1846@1,COG1846@2 NA|NA|NA K MarR family LPKNPDNH_00983 398513.BBNG_00374 0.0 1151.7 Bifidobacteriales ko:K06147,ko:K06148 ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2GITR@201174,4CZMX@85004,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter, ATP-binding protein LPKNPDNH_00984 398513.BBNG_00375 2.5e-278 964.1 Bifidobacteriales ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2GITR@201174,4CZPJ@85004,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region LPKNPDNH_00985 398513.BBNG_00375 4.6e-82 310.5 Bifidobacteriales ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 2GITR@201174,4CZPJ@85004,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region LPKNPDNH_00986 702459.BBPR_0464 2.3e-168 598.2 Bifidobacteriales ko:K07001 ko00000 Bacteria 2I8R7@201174,4CZUH@85004,COG4667@1,COG4667@2 NA|NA|NA S Patatin-like phospholipase LPKNPDNH_00987 398513.BBNG_00377 4.6e-154 550.4 Bifidobacteriales murI GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 R00260 RC00302 ko00000,ko00001,ko01000,ko01011 Bacteria 2GN4I@201174,4CZ54@85004,COG0796@1,COG0796@2 NA|NA|NA M Provides the (R)-glutamate required for cell wall biosynthesis LPKNPDNH_00988 398513.BBNG_00378 2.5e-169 601.3 Bifidobacteriales dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 iIT341.HP0566,iLJ478.TM1522 Bacteria 2GKUD@201174,4CYQP@85004,COG0253@1,COG0253@2 NA|NA|NA E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine LPKNPDNH_00989 398513.BBNG_00379 7.6e-115 419.9 Bifidobacteriales Bacteria 2GMVK@201174,4CZN1@85004,COG4243@1,COG4243@2 NA|NA|NA S Vitamin K epoxide reductase LPKNPDNH_00990 702459.BBPR_0468 1.9e-166 591.7 Bifidobacteriales PPA1328 3.1.3.97 ko:K07053 R00188,R11188 RC00078 ko00000,ko01000 Bacteria 2GNAP@201174,4CYQ5@85004,COG0613@1,COG0613@2 NA|NA|NA S DNA polymerase alpha chain like domain LPKNPDNH_00991 702459.BBPR_0469 6.1e-32 142.9 Bifidobacteriales Bacteria 2AS45@1,2HZSD@201174,31HGW@2,4D1H9@85004 NA|NA|NA S Protein of unknown function (DUF3107) LPKNPDNH_00992 702459.BBPR_0470 4.6e-245 853.6 Bifidobacteriales mphA Bacteria 2I8R6@201174,4CYPR@85004,COG3173@1,COG3173@2 NA|NA|NA S Aminoglycoside phosphotransferase LPKNPDNH_00993 702459.BBPR_0471 4.5e-280 969.9 Bifidobacteriales uvrD2 GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GKRW@201174,4CZ3A@85004,COG0210@1,COG0210@2 NA|NA|NA L DNA helicase LPKNPDNH_00994 702459.BBPR_0472 1.1e-286 991.9 Bifidobacteriales Bacteria 2GJ9K@201174,4CYU7@85004,COG5282@1,COG5282@2 NA|NA|NA S Zincin-like metallopeptidase LPKNPDNH_00995 398513.BBNG_00386 1.5e-152 545.4 Bifidobacteriales lon ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Bacteria 2GMFX@201174,4CYUP@85004,COG3480@1,COG3480@2 NA|NA|NA T Belongs to the peptidase S16 family LPKNPDNH_00996 398513.BBNG_00387 5.7e-47 193.7 Bifidobacteriales Bacteria 2B57P@1,2I89I@201174,32TPU@2,4D0P0@85004 NA|NA|NA S Protein of unknown function (DUF3052) LPKNPDNH_00997 398513.BBNG_00388 5.2e-195 686.8 Bifidobacteriales ko:K02529 ko00000,ko03000 Bacteria 2GJY9@201174,4CYU5@85004,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor LPKNPDNH_00998 398513.BBNG_00389 1.2e-61 242.3 Bifidobacteriales GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 Bacteria 2IQ7E@201174,4D14E@85004,COG0011@1,COG0011@2 NA|NA|NA S Thiamine-binding protein LPKNPDNH_00999 398513.BBNG_00390 3e-162 577.8 Bifidobacteriales thiD 2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17 ko:K00941,ko:K03147,ko:K14153 ko00730,ko01100,map00730,map01100 M00127 R03223,R03471,R03472,R04509,R10712 RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2909 Bacteria 2GKZM@201174,4CYQA@85004,COG0351@1,COG0351@2 NA|NA|NA H Phosphomethylpyrimidine kinase LPKNPDNH_01000 398513.BBNG_00391 6.9e-231 806.2 Bifidobacteriales ko:K13525 ko04141,ko05134,map04141,map05134 M00400,M00403 ko00000,ko00001,ko00002,ko03019,ko04131,ko04147 3.A.16.1 Bacteria 2I5C1@201174,4D0DP@85004,COG1222@1,COG1222@2 NA|NA|NA O AAA domain (Cdc48 subfamily) LPKNPDNH_01001 398513.BBNG_00393 1.3e-84 318.9 Bifidobacteriales Bacteria 2CK5B@1,2HU05@201174,2ZYDK@2,4D0JT@85004 NA|NA|NA LPKNPDNH_01002 398513.BBNG_00394 0.0 1847.8 Bifidobacteriales thiC GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17 ko:K00788,ko:K03147,ko:K14153 ko00730,ko01100,map00730,map01100 M00127 R03223,R03471,R03472,R04509,R10712 RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 iYO844.BSU08790,iYO844.BSU38290 Bacteria 2GJ3Y@201174,4D2W5@85004,COG0352@1,COG0352@2,COG0422@1,COG0422@2 NA|NA|NA H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction LPKNPDNH_01003 398513.BBNG_00395 2.9e-105 387.9 Bifidobacteriales thiM 2.7.1.50 ko:K00878 ko00730,ko01100,map00730,map01100 M00127 R04448 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2IC73@201174,4CZU8@85004,COG2145@1,COG2145@2 NA|NA|NA H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) LPKNPDNH_01004 702459.BBPR_0482 0.0 3683.3 Bifidobacteriales lacZ GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 Bacteria 2GMAT@201174,4CYRA@85004,COG1196@1,COG1196@2,COG3250@1,COG3250@2 NA|NA|NA G Domain of unknown function (DUF4982) LPKNPDNH_01005 702459.BBPR_0483 7.9e-301 1038.9 Bifidobacteriales glyQS GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iSB619.SA_RS07880 Bacteria 2GIT3@201174,4CYZU@85004,COG0423@1,COG0423@2 NA|NA|NA J Catalyzes the attachment of glycine to tRNA(Gly) LPKNPDNH_01006 398513.BBNG_00399 3.6e-246 857.1 Bifidobacteriales dus GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090 Bacteria 2GJ8I@201174,4CZFD@85004,COG0042@1,COG0042@2 NA|NA|NA J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines LPKNPDNH_01007 398513.BBNG_00400 7.3e-231 806.2 Bifidobacteriales ftsZ GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Bacteria 2GJWC@201174,4CZ10@85004,COG0206@1,COG0206@2 NA|NA|NA D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity LPKNPDNH_01008 398513.BBNG_00401 4.3e-80 303.9 Bifidobacteriales sepF GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0051301,GO:0071840,GO:0090529 ko:K09772 ko00000,ko03036 Bacteria 2GNVH@201174,4D0RJ@85004,COG1799@1,COG1799@2 NA|NA|NA D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA LPKNPDNH_01009 398513.BBNG_00402 2.1e-42 177.9 Bifidobacteriales yggT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02221 ko00000,ko02044 Bacteria 2GQI1@201174,4D17B@85004,COG0762@1,COG0762@2 NA|NA|NA S YGGT family LPKNPDNH_01010 398513.BBNG_00404 9.7e-90 337.4 Bifidobacteriales 3.1.21.3 ko:K01153,ko:K02557,ko:K10352,ko:K18682 ko02030,ko02040,ko03018,ko04530,map02030,map02040,map03018,map04530 ko00000,ko00001,ko01000,ko02000,ko02035,ko02048,ko03019,ko04147,ko04812 1.A.30.1 Bacteria 2I2G9@201174,4CZ5W@85004,COG1566@1,COG1566@2 NA|NA|NA V DivIVA protein LPKNPDNH_01011 398513.BBNG_00405 4e-103 380.9 Bifidobacteriales lspA 3.4.23.36 ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 2GKRX@201174,4D0WR@85004,COG0597@1,COG0597@2 NA|NA|NA MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins LPKNPDNH_01012 398513.BBNG_00406 9.9e-177 625.9 Bifidobacteriales rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 ko00000,ko01000,ko03009,ko03016 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 2GIY1@201174,4CYYR@85004,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil LPKNPDNH_01014 398513.BBNG_00409 6e-63 246.5 Bifidobacteriales Bacteria 2DMQA@1,2GPRU@201174,32SZE@2,4D1R8@85004 NA|NA|NA LPKNPDNH_01015 398513.BBNG_00410 2.6e-138 498.4 Bifidobacteriales dapD GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1201c Bacteria 2GIZ9@201174,4CYVT@85004,COG2171@1,COG2171@2 NA|NA|NA E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA LPKNPDNH_01016 398513.BBNG_00412 3.7e-202 710.7 Bifidobacteriales prfB GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02836 ko00000,ko03012 Bacteria 2GJ0F@201174,4CZJX@85004,COG1186@1,COG1186@2 NA|NA|NA J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA LPKNPDNH_01017 398513.BBNG_00413 1e-188 666.4 Bifidobacteriales ftsE GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 ko:K09811,ko:K09812 ko02010,map02010 M00256 ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 Bacteria 2GJE1@201174,4CYYQ@85004,COG2884@1,COG2884@2 NA|NA|NA D Cell division ATP-binding protein FtsE LPKNPDNH_01018 398513.BBNG_00414 2.4e-159 568.2 Bifidobacteriales ftsX GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0042173,GO:0042221,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0090529,GO:1902531 ko:K09811,ko:K09812 ko02010,map02010 M00256 ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 Bacteria 2GJMA@201174,4CZSQ@85004,COG2177@1,COG2177@2 NA|NA|NA D Part of the ABC transporter FtsEX involved in cellular division LPKNPDNH_01019 702459.BBPR_0498 2.5e-163 582.0 Bifidobacteriales usp 3.5.1.28 ko:K21471,ko:K22409 ko00000,ko01000,ko01002,ko01011 CBM50 Bacteria 2GZG8@201174,4CYQJ@85004,COG3942@1,COG3942@2 NA|NA|NA D CHAP domain protein LPKNPDNH_01020 398513.BBNG_00416 3e-76 291.2 Bifidobacteriales smpB GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 ko:K03664 ko00000 Bacteria 2GJX1@201174,4CZG4@85004,COG0691@1,COG0691@2 NA|NA|NA J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA LPKNPDNH_01021 702459.BBPR_0500 1.2e-145 522.3 Bifidobacteriales rluA 5.4.99.28,5.4.99.29 ko:K06177 ko00000,ko01000,ko03009,ko03016 Bacteria 2GJ2Z@201174,4CZB2@85004,COG0564@1,COG0564@2 NA|NA|NA J RNA pseudouridylate synthase LPKNPDNH_01022 1437610.BREU_1425 4.6e-82 310.8 Bifidobacteriales Bacteria 2BFV3@1,2IT9I@201174,329QD@2,4D1CE@85004 NA|NA|NA LPKNPDNH_01024 398513.BBNG_00422 3.4e-198 698.0 Bifidobacteriales 2.7.11.1 ko:K08884,ko:K12132 ko00000,ko01000,ko01001 Bacteria 2I2GE@201174,4CZDF@85004,COG3170@1,COG3170@2 NA|NA|NA NU Tfp pilus assembly protein FimV LPKNPDNH_01025 702459.BBPR_0505 1.2e-222 778.9 Bifidobacteriales dxr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1814,iECOK1_1307.ECOK1_0174,iECS88_1305.ECS88_0183,iHN637.CLJU_RS06420,iUMN146_1321.UM146_23670,iUTI89_1310.UTI89_C0188 Bacteria 2GIRV@201174,4CZVC@85004,COG0743@1,COG0743@2 NA|NA|NA I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) LPKNPDNH_01026 702459.BBPR_0507 4.7e-236 823.5 Bifidobacteriales ispG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS06430,iJN678.gcpE Bacteria 2GK2S@201174,4CYQB@85004,COG0821@1,COG0821@2 NA|NA|NA I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate LPKNPDNH_01027 398513.BBNG_00425 4.7e-291 1006.5 Bifidobacteriales Bacteria 2I2GD@201174,4CZUD@85004,COG0657@1,COG0657@2 NA|NA|NA I acetylesterase activity LPKNPDNH_01028 702459.BBPR_0509 4.3e-141 507.3 Bifidobacteriales recO GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 2GK81@201174,4CZCN@85004,COG1381@1,COG1381@2 NA|NA|NA L Involved in DNA repair and RecF pathway recombination LPKNPDNH_01029 398513.BBNG_00427 5.3e-155 553.5 Bifidobacteriales uppS GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.86,2.5.1.88 ko:K00806,ko:K14215,ko:K21273 ko00900,ko01110,map00900,map01110 R06447,R09244,R09731 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 Bacteria 2GIXF@201174,4CZAR@85004,COG0020@1,COG0020@2 NA|NA|NA H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids LPKNPDNH_01030 702459.BBPR_0511 9.6e-191 672.5 Bifidobacteriales ywqG Bacteria 2GSR1@201174,4D1R0@85004,COG3878@1,COG3878@2 NA|NA|NA S Domain of unknown function (DUF1963) LPKNPDNH_01031 216816.GS08_07075 6.5e-15 85.9 Bifidobacteriales cscA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 GH32 iE2348C_1286.E2348C_2556,iEC55989_1330.EC55989_2656,iECIAI1_1343.ECIAI1_2428 Bacteria 2GJ9T@201174,4CZ8W@85004,COG1621@1,COG1621@2 NA|NA|NA G Belongs to the glycosyl hydrolase 32 family LPKNPDNH_01032 398513.BBNG_00429 3e-39 167.2 Bacteria cscA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 GH32 iE2348C_1286.E2348C_2556,iEC55989_1330.EC55989_2656,iECIAI1_1343.ECIAI1_2428 Bacteria COG1621@1,COG1621@2 NA|NA|NA G Belongs to the glycosyl hydrolase 32 family LPKNPDNH_01033 398513.BBNG_00430 0.0 2394.4 Bifidobacteriales dnaE 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GJ1P@201174,4CZKT@85004,COG0587@1,COG0587@2 NA|NA|NA L DNA polymerase III alpha subunit LPKNPDNH_01034 702459.BBPR_0515 7.6e-106 390.2 Bifidobacteriales Bacteria 2BHFF@1,2GV2H@201174,32BHI@2,4D1HU@85004 NA|NA|NA S zinc-ribbon domain LPKNPDNH_01035 702459.BBPR_0516 1.6e-46 191.8 Bifidobacteriales yhbY GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275 ko:K07574 ko00000,ko03009 Bacteria 2IKSS@201174,4D10K@85004,COG1534@1,COG1534@2 NA|NA|NA J CRS1_YhbY LPKNPDNH_01036 702459.BBPR_0517 0.0 1312.0 Bifidobacteriales 4.2.1.53 ko:K10254 ko00000,ko01000 Bacteria 2GKZ8@201174,4CYZK@85004,COG4716@1,COG4716@2 NA|NA|NA S MCRA family LPKNPDNH_01038 398513.BBNG_00435 3.4e-202 710.7 Bifidobacteriales ko:K07012 ko00000,ko01000,ko02048 Bacteria 2IAIA@201174,4CYRS@85004,COG2378@1,COG2378@2 NA|NA|NA K WYL domain LPKNPDNH_01039 398513.BBNG_00436 5e-156 557.0 Bifidobacteriales yvgN 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 Bacteria 2GJQ7@201174,4CZ1F@85004,COG0656@1,COG0656@2 NA|NA|NA S Aldo/keto reductase family LPKNPDNH_01040 702459.BBPR_0520 6.4e-173 613.2 Bifidobacteriales dkgA GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008106,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0055114,GO:0071704,GO:1901575 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 iECH74115_1262.ECH74115_4323,iECSP_1301.ECSP_3988 Bacteria 2GJQ7@201174,4CZXR@85004,COG0656@1,COG0656@2 NA|NA|NA C Aldo/keto reductase family LPKNPDNH_01041 702459.BBPR_0521 1.2e-76 292.4 Bifidobacteriales yneG Bacteria 2DMJC@1,2IHZV@201174,32RYJ@2,4D0UY@85004 NA|NA|NA S Domain of unknown function (DUF4186) LPKNPDNH_01043 762211.BSTEL_2175 3.9e-07 60.5 Bifidobacteriales pbpB 2.7.11.1,3.4.16.4 ko:K03587,ko:K08384,ko:K08724,ko:K08884,ko:K12132 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01001,ko01011,ko03036 Bacteria 2IAHD@201174,4D094@85004,COG2815@1,COG2815@2 NA|NA|NA S PASTA domain LPKNPDNH_01044 398513.BBNG_00441 2.3e-181 641.3 Bifidobacteriales gmk 1.1.1.23,2.7.4.8 ko:K00013,ko:K00942 ko00230,ko00340,ko01100,ko01110,ko01230,map00230,map00340,map01100,map01110,map01230 M00026,M00050 R00332,R01158,R01163,R02090,R03012 RC00002,RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 Bacteria 2HTNX@201174,4D0CP@85004,COG2852@1,COG2852@2 NA|NA|NA S Protein conserved in bacteria LPKNPDNH_01045 398513.BBNG_00443 2.5e-256 891.0 Bifidobacteriales hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,1.1.1.308 ko:K00013,ko:K15509 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1599 Bacteria 2GKKA@201174,4CZ3E@85004,COG0141@1,COG0141@2 NA|NA|NA E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine LPKNPDNH_01046 398513.BBNG_00444 1.2e-224 785.4 Bifidobacteriales hisC GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GJ9W@201174,4CZDT@85004,COG0079@1,COG0079@2 NA|NA|NA E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily LPKNPDNH_01047 398513.BBNG_00445 3.2e-112 411.0 Bifidobacteriales hisB GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,2.6.1.9,3.1.3.15,4.2.1.19 ko:K00013,ko:K00817,ko:K01089,ko:K01693 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R01158,R01163,R03012,R03013,R03243,R03457 RC00006,RC00017,RC00099,RC00242,RC00463,RC00888,RC00932 ko00000,ko00001,ko00002,ko01000,ko01007 iECO111_1330.ECO111_2746,iECS88_1305.ECS88_2121,iJN746.PP_0289,iLJ478.TM1039,iSB619.SA_RS14130,iUMNK88_1353.UMNK88_2570 Bacteria 2GKMD@201174,4CZDD@85004,COG0131@1,COG0131@2 NA|NA|NA E Imidazoleglycerol-phosphate dehydratase LPKNPDNH_01048 398513.BBNG_00446 5.9e-113 413.7 Bifidobacteriales Bacteria 2EKCN@1,2GNIC@201174,33E2Y@2,4D0B5@85004 NA|NA|NA LPKNPDNH_01049 398513.BBNG_00447 4.8e-122 443.7 Bifidobacteriales hisH GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIYS@201174,4CZGA@85004,COG0118@1,COG0118@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR LPKNPDNH_01050 398513.BBNG_00448 1.7e-131 475.3 Bifidobacteriales hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16,5.3.1.24 ko:K01814,ko:K01817 ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230 M00023,M00026 R03509,R04640 RC00945 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ4V@201174,4CZEA@85004,COG0106@1,COG0106@2 NA|NA|NA E Histidine biosynthesis protein LPKNPDNH_01051 398513.BBNG_00449 5.4e-283 979.5 Bifidobacteriales Bacteria 2GKEK@201174,4CZIY@85004,COG4320@1,COG4320@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2252) LPKNPDNH_01052 398513.BBNG_00450 2.1e-265 921.0 Bifidobacteriales glnA2 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 2GJ2I@201174,4CZ0G@85004,COG0174@1,COG0174@2 NA|NA|NA E glutamine synthetase LPKNPDNH_01053 398513.BBNG_00451 1.4e-248 865.1 Bifidobacteriales Bacteria 2AZXA@1,2GQBM@201174,31S72@2,4D1E0@85004 NA|NA|NA S Domain of unknown function (DUF5067) LPKNPDNH_01054 398513.BBNG_00452 1.1e-57 229.2 Bacteria ko:K08369 ko00000,ko02000 2.A.1 Bacteria COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily LPKNPDNH_01055 702459.BBPR_0534 1.4e-176 625.5 Bifidobacteriales Bacteria 2HYIN@201174,4CYU1@85004,COG5479@1,COG5479@2 NA|NA|NA M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses LPKNPDNH_01056 702459.BBPR_0535 0.0 2685.2 Bifidobacteriales hrpA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K03578 ko00000,ko01000 Bacteria 2GIWX@201174,4CZ3C@85004,COG1643@1,COG1643@2 NA|NA|NA L Helicase associated domain (HA2) Add an annotation LPKNPDNH_01057 702459.BBPR_0536 2.4e-121 441.4 Bifidobacteriales rsmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.172 ko:K00564 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 2IFG7@201174,4CZP1@85004,COG2813@1,COG2813@2 NA|NA|NA J Ribosomal protein L11 methyltransferase (PrmA) LPKNPDNH_01058 398513.BBNG_00456 3.9e-173 614.0 Bifidobacteriales Bacteria 29PMQ@1,2I95H@201174,30AJW@2,4D0N6@85004 NA|NA|NA LPKNPDNH_01059 398513.BBNG_00457 3.1e-273 947.2 Bifidobacteriales hflX GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 ko:K03665 ko00000,ko03009 Bacteria 2GK55@201174,4CZCB@85004,COG2262@1,COG2262@2 NA|NA|NA S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis LPKNPDNH_01060 398513.BBNG_00458 4.6e-177 627.1 Bifidobacteriales ldh 1.1.1.27,1.1.1.37 ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R00703,R01000,R03104,R07136 RC00031,RC00044 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GN5S@201174,4CYWK@85004,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily. LDH family LPKNPDNH_01061 398513.BBNG_00459 1.2e-166 592.4 Bifidobacteriales czcD ko:K16264 ko00000,ko02000 2.A.4.1 Bacteria 2GMRZ@201174,4CZAB@85004,COG1230@1,COG1230@2 NA|NA|NA P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family LPKNPDNH_01062 398513.BBNG_00460 7.5e-129 466.5 Bifidobacteriales lexA 3.4.21.88 ko:K01356 M00729 ko00000,ko00002,ko01000,ko01002,ko03400 Bacteria 2GMBN@201174,4CZ26@85004,COG1974@1,COG1974@2 NA|NA|NA K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair LPKNPDNH_01063 702459.BBPR_0543 1.5e-43 181.8 Bifidobacteriales Bacteria 2HVH4@201174,4D1G8@85004,COG1388@1,COG1388@2 NA|NA|NA M Lysin motif LPKNPDNH_01064 398513.BBNG_00462 1.1e-82 312.8 Bifidobacteriales nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K07738 ko00000,ko03000 Bacteria 2IHU9@201174,4D0P7@85004,COG1327@1,COG1327@2 NA|NA|NA K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes LPKNPDNH_01065 398513.BBNG_00463 3.2e-228 797.3 Bifidobacteriales serA GO:0003674,GO:0003824,GO:0004617,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008219,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0012501,GO:0016053,GO:0016491,GO:0016597,GO:0016614,GO:0016616,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047545,GO:0055114,GO:0070905,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 iYL1228.KPN_03348 Bacteria 2GJGA@201174,4CYPT@85004,COG0111@1,COG0111@2 NA|NA|NA EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain LPKNPDNH_01066 702459.BBPR_0546 0.0 1468.8 Bifidobacteriales Bacteria 2GK30@201174,4CYUF@85004,COG3973@1,COG3973@2 NA|NA|NA L DNA helicase LPKNPDNH_01067 398513.BBNG_00465 1.4e-89 335.5 Bifidobacteriales mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 ko:K03925 ko00000 Bacteria 2IHUB@201174,4D0P1@85004,COG2001@1,COG2001@2 NA|NA|NA K Belongs to the MraZ family LPKNPDNH_01068 398513.BBNG_00466 1.1e-193 682.6 Bifidobacteriales rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 ko00000,ko01000,ko03009 Bacteria 2GJGK@201174,4CYRM@85004,COG0275@1,COG0275@2 NA|NA|NA J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA LPKNPDNH_01069 702459.BBPR_0549 2.5e-59 235.0 Bifidobacteriales ftsL ko:K05589,ko:K12065 ko00000,ko02044,ko03036 3.A.7.11.1 Bacteria 2IKUA@201174,4D109@85004,COG2919@1,COG2919@2 NA|NA|NA D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic LPKNPDNH_01070 702459.BBPR_0550 0.0 1164.1 Bifidobacteriales ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587,ko:K08384,ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 iSSON_1240.SSON_0092 Bacteria 2GKHH@201174,4CYS8@85004,COG0768@1,COG0768@2 NA|NA|NA M Penicillin-binding protein, transpeptidase domain protein LPKNPDNH_01071 702459.BBPR_0551 2.8e-180 637.9 Bifidobacteriales yqeC 6.3.2.10,6.3.2.13 ko:K01928,ko:K15792 ko00300,ko00550,map00300,map00550 R02788,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 2GMZF@201174,4CYWT@85004,COG0769@1,COG0769@2 NA|NA|NA M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan LPKNPDNH_01072 398513.BBNG_00469 4e-284 983.4 Bifidobacteriales murF 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 2GK0Y@201174,4CZ7U@85004,COG0770@1,COG0770@2 NA|NA|NA M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein LPKNPDNH_01073 398513.BBNG_00470 1.8e-201 708.4 Bifidobacteriales mraY GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105 Bacteria 2GNEH@201174,4CYRX@85004,COG0472@1,COG0472@2 NA|NA|NA M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan LPKNPDNH_01074 702459.BBPR_0554 2.7e-266 924.1 Bifidobacteriales murD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 iNJ661.Rv2155c Bacteria 2GJZA@201174,4CZKI@85004,COG0771@1,COG0771@2 NA|NA|NA M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) LPKNPDNH_01075 702459.BBPR_0555 4e-224 783.9 Bifidobacteriales ftsW GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008360,GO:0009987,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032153,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505 2.4.1.227 ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 2.A.103.1 GT28 Bacteria 2GKXP@201174,4CYPZ@85004,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family LPKNPDNH_01076 398513.BBNG_00473 1.7e-218 765.0 Bifidobacteriales murG GO:0008150,GO:0040007 2.4.1.227,6.3.2.8 ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 R03193,R05032,R05662 RC00005,RC00049,RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 GT28 iLJ478.TM0232 Bacteria 2GJEM@201174,4CYQS@85004,COG0707@1,COG0707@2 NA|NA|NA M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) LPKNPDNH_01077 398513.BBNG_00474 1.8e-295 1021.1 Bifidobacteriales murC GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 2I2E7@201174,4CZ3B@85004,COG0773@1,COG0773@2 NA|NA|NA M Belongs to the MurCDEF family LPKNPDNH_01078 702459.BBPR_0558 4.7e-158 564.3 Bifidobacteriales ftsQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 6.3.2.4 ko:K01921,ko:K03589,ko:K06438 ko00473,ko00550,ko01100,ko01502,ko04112,map00473,map00550,map01100,map01502,map04112 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011,ko03036 Bacteria 2H4A4@201174,4D04A@85004,COG1589@1,COG1589@2 NA|NA|NA D Cell division protein FtsQ LPKNPDNH_01079 398513.BBNG_00476 1.3e-37 162.5 Bifidobacteriales Bacteria 2B3SJ@1,2GX7W@201174,31WG6@2,4D1T0@85004 NA|NA|NA LPKNPDNH_01081 398513.BBNG_00478 2.3e-85 321.6 Bifidobacteriales dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360 ko:K07560 ko00000,ko01000,ko03016 Bacteria 2IKVR@201174,4D0VE@85004,COG1490@1,COG1490@2 NA|NA|NA J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality LPKNPDNH_01082 702459.BBPR_0561 4.4e-236 823.5 Bifidobacteriales Bacteria 2I966@201174,4CZRX@85004,COG0738@1,COG0738@2 NA|NA|NA G Major Facilitator Superfamily LPKNPDNH_01083 398513.BBNG_00480 1.9e-169 601.7 Bifidobacteriales 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2HZB3@201174,4CZFC@85004,COG0524@1,COG0524@2 NA|NA|NA G pfkB family carbohydrate kinase LPKNPDNH_01084 398513.BBNG_00481 4.5e-222 776.9 Bifidobacteriales Bacteria 2GJ2S@201174,4CYV9@85004,COG1940@1,COG1940@2 NA|NA|NA GK ROK family LPKNPDNH_01085 702459.BBPR_0564 9.9e-132 476.1 Bifidobacteriales cutC ko:K06201 ko00000 Bacteria 2GKI8@201174,4D054@85004,COG3142@1,COG3142@2 NA|NA|NA P Participates in the control of copper homeostasis LPKNPDNH_01086 398513.BBNG_00483 7e-217 759.6 Bifidobacteriales Bacteria 2GKMZ@201174,4CZUF@85004,COG1940@1,COG1940@2 NA|NA|NA GK ROK family LPKNPDNH_01087 702459.BBPR_0566 6.6e-153 546.6 Bifidobacteriales nagB 3.1.1.31,3.5.99.6 ko:K01057,ko:K02564 ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R00765,R02035 RC00163,RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK7F@201174,4CYYE@85004,COG0363@1,COG0363@2 NA|NA|NA G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion LPKNPDNH_01088 702459.BBPR_0567 1.1e-213 749.2 Bifidobacteriales nagA 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 R02059 RC00166,RC00300 ko00000,ko00001,ko01000 Bacteria 2GK1E@201174,4CZKB@85004,COG1820@1,COG1820@2 NA|NA|NA G Amidohydrolase family LPKNPDNH_01089 702459.BBPR_0568 2e-305 1054.3 Bifidobacteriales ddpA ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GMAX@201174,4D2RC@85004,COG0747@1,COG0747@2 NA|NA|NA E Bacterial extracellular solute-binding proteins, family 5 Middle LPKNPDNH_01090 702459.BBPR_0569 6.7e-185 653.3 Bifidobacteriales dppB ko:K02033 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GJ2C@201174,4CZSV@85004,COG0601@1,COG0601@2 NA|NA|NA EP Binding-protein-dependent transport system inner membrane component LPKNPDNH_01091 398513.BBNG_00488 1.9e-190 671.8 Bifidobacteriales dppC ko:K02034 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GKAW@201174,4CZ2Y@85004,COG1173@1,COG1173@2 NA|NA|NA EP Binding-protein-dependent transport system inner membrane component LPKNPDNH_01092 398513.BBNG_00489 0.0 1114.0 Bifidobacteriales ko:K02031,ko:K02032 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2H3HY@201174,4CYU0@85004,COG1123@1,COG4172@2 NA|NA|NA P Belongs to the ABC transporter superfamily LPKNPDNH_01093 398513.BBNG_00490 0.0 1083.2 Bifidobacteriales pepP 3.4.11.9 ko:K01262 ko00000,ko01000,ko01002 Bacteria 2GM7D@201174,4CZIA@85004,COG0006@1,COG0006@2 NA|NA|NA E Aminopeptidase P, N-terminal domain LPKNPDNH_01094 398513.BBNG_00491 9.6e-97 359.4 Bifidobacteriales 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 2IKKB@201174,4CZS4@85004,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain LPKNPDNH_01096 398513.BBNG_00492 4.7e-283 979.9 Bifidobacteriales folC GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2447c Bacteria 2GJP2@201174,4CZG9@85004,COG0285@1,COG0285@2 NA|NA|NA H Mur ligase middle domain LPKNPDNH_01097 398513.BBNG_00493 0.0 2199.5 Bifidobacteriales smc GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K03529,ko:K19171 ko00000,ko02048,ko03036 Bacteria 2GK93@201174,4CZ8Q@85004,COG1196@1,COG1196@2 NA|NA|NA D Required for chromosome condensation and partitioning LPKNPDNH_01098 398513.BBNG_00494 2.8e-128 464.5 Bifidobacteriales racD 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 R00491 RC00302 ko00000,ko00001,ko01000 Bacteria 2H7J9@201174,4D05Z@85004,COG1794@1,COG1794@2 NA|NA|NA G Belongs to the aspartate glutamate racemases family LPKNPDNH_01099 702459.BBPR_0578 9.5e-244 849.0 Bifidobacteriales yxbA 6.3.1.12 ko:K17810 ko00000,ko01000 Bacteria 2GM4D@201174,4CZV2@85004,COG3919@1,COG3919@2 NA|NA|NA S ATP-grasp LPKNPDNH_01100 702459.BBPR_0579 1.1e-228 798.9 Bifidobacteriales 2.6.1.33 ko:K20429 R02773 RC00006,RC00781 ko00000,ko01000 Bacteria 2GKBC@201174,4D083@85004,COG0399@1,COG0399@2 NA|NA|NA M DegT/DnrJ/EryC1/StrS aminotransferase family LPKNPDNH_01101 398513.BBNG_00497 6.8e-192 676.4 Bifidobacteriales Bacteria 2GJUD@201174,4CZT9@85004,COG2348@1,COG2348@2 NA|NA|NA V Acetyltransferase (GNAT) domain LPKNPDNH_01102 398513.BBNG_00498 4.2e-297 1026.5 Bifidobacteriales murE 6.3.2.13,6.3.2.7 ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 R02786,R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 Bacteria 2GIS2@201174,4CZAF@85004,COG0769@1,COG0769@2 NA|NA|NA M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan LPKNPDNH_01103 398513.BBNG_00499 2.1e-114 418.3 Bifidobacteriales sigH ko:K03088 ko00000,ko03021 Bacteria 2GJ02@201174,4CZ09@85004,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family. ECF subfamily LPKNPDNH_01104 702459.BBPR_0583 2e-64 251.5 Bifidobacteriales Bacteria 29M53@1,2GTWX@201174,3082I@2,4D1EJ@85004 NA|NA|NA LPKNPDNH_01105 398513.BBNG_00502 1.4e-194 685.3 Bifidobacteriales galM 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ0H@201174,4CYWN@85004,COG2017@1,COG2017@2 NA|NA|NA G Aldose 1-epimerase LPKNPDNH_01106 398513.BBNG_00503 2e-180 638.3 Bifidobacteriales ispH 1.17.7.4,2.7.4.25 ko:K00945,ko:K02945,ko:K03527 ko00240,ko00900,ko01100,ko01110,ko01130,ko03010,map00240,map00900,map01100,map01110,map01130,map03010 M00052,M00096,M00178 R00158,R00512,R01665,R05884,R08210 RC00002,RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 iIT341.HP0400,iLJ478.TM1444 Bacteria 2GIZ7@201174,4CZ8B@85004,COG0761@1,COG0761@2 NA|NA|NA IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis LPKNPDNH_01108 702459.BBPR_0586 2.4e-92 344.7 Bifidobacteriales ybaK GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0043907,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 ko:K03976 ko00000,ko01000,ko03016 Bacteria 2IHS8@201174,4CZFI@85004,COG2606@1,COG2606@2 NA|NA|NA J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily LPKNPDNH_01109 398513.BBNG_00506 1e-198 699.1 Bifidobacteriales gap GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009986,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019362,GO:0019637,GO:0019674,GO:0022610,GO:0034641,GO:0036094,GO:0043891,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044464,GO:0044650,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051704,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0097159,GO:0140030,GO:0140032,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 iJR904.b1416,iJR904.b1417 Bacteria 2GJK4@201174,4CZ97@85004,COG0057@1,COG0057@2 NA|NA|NA G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family LPKNPDNH_01110 702459.BBPR_0588 8e-134 483.0 Bifidobacteriales 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 R00619 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2HQZZ@201174,4CZBY@85004,COG1564@1,COG1564@2 NA|NA|NA H Thiamin pyrophosphokinase, vitamin B1 binding domain LPKNPDNH_01111 398513.BBNG_00508 7.1e-68 263.1 Bifidobacteriales Bacteria 2I372@201174,4D060@85004,COG4262@1,COG4262@2 NA|NA|NA S Spermine/spermidine synthase domain LPKNPDNH_01112 398513.BBNG_00509 1.4e-103 382.5 Bifidobacteriales infC GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 ko:K02520 ko00000,ko03012,ko03029 Bacteria 2GJGT@201174,4CZA3@85004,COG0290@1,COG0290@2 NA|NA|NA J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins LPKNPDNH_01113 398513.BBNG_00510 2.1e-25 120.9 Bifidobacteriales rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02916 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2HZRM@201174,4D1EV@85004,COG0291@1,COG0291@2 NA|NA|NA J Ribosomal protein L35 LPKNPDNH_01114 398513.BBNG_00511 9.6e-62 242.7 Bifidobacteriales rplT GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02887 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHTN@201174,4D0QF@85004,COG0292@1,COG0292@2 NA|NA|NA J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit LPKNPDNH_01115 398513.BBNG_00512 5.8e-180 636.7 Bifidobacteriales xerD GO:0008150,GO:0040007 ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 2GNDP@201174,4CZ69@85004,COG4974@1,COG4974@2 NA|NA|NA D recombinase XerD LPKNPDNH_01116 398513.BBNG_00513 1.8e-152 545.4 Bifidobacteriales soj GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 ko:K03496 ko00000,ko03036,ko04812 Bacteria 2GJX3@201174,4CYV4@85004,COG1192@1,COG1192@2 NA|NA|NA D CobQ CobB MinD ParA nucleotide binding domain protein LPKNPDNH_01117 398513.BBNG_00514 2.3e-148 531.6 Bifidobacteriales scpA ko:K05896 ko00000,ko03036 Bacteria 2GN1U@201174,4CYRV@85004,COG1354@1,COG1354@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves LPKNPDNH_01118 702459.BBPR_0597 2.5e-98 364.8 Bifidobacteriales scpB ko:K06024 ko00000,ko03036 Bacteria 2GISY@201174,4D0QW@85004,COG1386@1,COG1386@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves LPKNPDNH_01119 398513.BBNG_00516 5.6e-149 533.5 Bifidobacteriales nrtR 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 2GNMT@201174,4CZNZ@85004,COG1051@1,COG1051@2 NA|NA|NA F NUDIX hydrolase LPKNPDNH_01120 398513.BBNG_00517 3.7e-251 873.6 Bifidobacteriales nadA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM59@201174,4D0AI@85004,COG0379@1,COG0379@2 NA|NA|NA H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate LPKNPDNH_01121 702459.BBPR_0600 0.0 1080.1 Bifidobacteriales nadB GO:0008150,GO:0040007 1.3.5.4,1.4.3.16,2.4.2.19 ko:K00244,ko:K00278,ko:K00767 ko00020,ko00190,ko00250,ko00620,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00250,map00620,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00115,M00150,M00173 R00357,R00481,R02164,R03348 RC00006,RC00045,RC02566,RC02877 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1595 Bacteria 2I2IJ@201174,4D01P@85004,COG0029@1,COG0029@2 NA|NA|NA H Catalyzes the oxidation of L-aspartate to iminoaspartate LPKNPDNH_01122 398513.BBNG_00519 1.4e-164 585.5 Bifidobacteriales nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0030312,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 1.4.3.16,2.4.2.19 ko:K00278,ko:K00767 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481,R03348 RC00006,RC02566,RC02877 ko00000,ko00001,ko00002,ko01000 Bacteria 2GV9P@201174,4CZWA@85004,COG0157@1,COG0157@2 NA|NA|NA H Quinolinate phosphoribosyl transferase, N-terminal domain LPKNPDNH_01123 398513.BBNG_00520 8e-238 829.3 Bifidobacteriales iscS1 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 2GKUT@201174,4CZVW@85004,COG1104@1,COG1104@2 NA|NA|NA E Aminotransferase class-V LPKNPDNH_01124 398513.BBNG_00521 0.0 1268.1 Bifidobacteriales typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 ko:K06207 ko00000 Bacteria 2GJUJ@201174,4CYX3@85004,COG1217@1,COG1217@2 NA|NA|NA T Elongation factor G C-terminus LPKNPDNH_01125 702459.BBPR_0604 5.5e-92 343.6 Bifidobacteriales Bacteria 2E9EF@1,2IKWQ@201174,333MW@2,4D10T@85004 NA|NA|NA LPKNPDNH_01126 398513.BBNG_00523 5.5e-197 693.3 Bifidobacteriales pheA 1.3.1.12,4.2.1.51,5.4.99.5 ko:K04517,ko:K04518,ko:K14170 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715,R01728 RC00125,RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJQ5@201174,4CZ61@85004,COG0077@1,COG0077@2 NA|NA|NA E Prephenate dehydratase LPKNPDNH_01127 398513.BBNG_00524 1.1e-192 679.1 Bifidobacteriales tyrA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 ko:K00210,ko:K00220,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025,M00040 R00732,R01728 RC00125 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKB4@201174,4CYV2@85004,COG0287@1,COG0287@2 NA|NA|NA E Prephenate dehydrogenase LPKNPDNH_01128 398513.BBNG_00525 7.3e-42 176.0 Bifidobacteriales Bacteria 2BGJ3@1,2IR91@201174,32AHC@2,4D17H@85004 NA|NA|NA LPKNPDNH_01129 398513.BBNG_00526 1.3e-187 662.1 Bifidobacteriales xerC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 2GNDP@201174,4CZCX@85004,COG4974@1,COG4974@2 NA|NA|NA D Belongs to the 'phage' integrase family. XerC subfamily LPKNPDNH_01130 398513.BBNG_00527 1.8e-176 625.2 Bifidobacteriales appB GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 ko:K02033 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GJ2C@201174,4CYS5@85004,COG0601@1,COG0601@2 NA|NA|NA EP Binding-protein-dependent transport system inner membrane component LPKNPDNH_01131 398513.BBNG_00528 4.6e-166 590.5 Bifidobacteriales dppC ko:K02034 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GJ9E@201174,4CYQF@85004,COG1173@1,COG1173@2 NA|NA|NA EP N-terminal TM domain of oligopeptide transport permease C LPKNPDNH_01132 398513.BBNG_00529 0.0 1455.3 Bifidobacteriales oppD ko:K02031,ko:K02032 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2H3HY@201174,4CYU0@85004,COG1123@1,COG4172@2 NA|NA|NA P Belongs to the ABC transporter superfamily LPKNPDNH_01133 702459.BBPR_0612 0.0 1134.0 Bifidobacteriales oppA ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 2GJ9N@201174,4CZ3S@85004,COG0747@1,COG0747@2 NA|NA|NA E Bacterial extracellular solute-binding proteins, family 5 Middle LPKNPDNH_01134 398513.BBNG_00531 3.1e-275 953.7 Bifidobacteriales pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 ko00000,ko01000,ko01002 Bacteria 2HCVR@201174,4CZD8@85004,COG3579@1,COG3579@2 NA|NA|NA E Peptidase C1-like family LPKNPDNH_01135 702459.BBPR_0614 1.1e-169 602.4 Bifidobacteriales exoA 3.1.11.2 ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2GKIS@201174,4CYVB@85004,COG0708@1,COG0708@2 NA|NA|NA L Endonuclease/Exonuclease/phosphatase family LPKNPDNH_01136 702459.BBPR_0615 2.1e-138 498.4 Bifidobacteriales Bacteria 28J4D@1,2GJYC@201174,2Z90C@2,4CZG1@85004 NA|NA|NA S Protein of unknown function (DUF3710) LPKNPDNH_01137 702459.BBPR_0616 6.1e-124 450.3 Bifidobacteriales Bacteria 2AVV0@1,2GJKP@201174,31MNQ@2,4CYQX@85004 NA|NA|NA S Protein of unknown function (DUF3159) LPKNPDNH_01138 398513.BBNG_00535 4.5e-249 866.7 Bifidobacteriales trmA GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0019843,GO:0030488,GO:0030696,GO:0030697,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 ko00000,ko01000,ko03009,ko03016 Bacteria 2GIR3@201174,4CYYN@85004,COG2265@1,COG2265@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family LPKNPDNH_01139 398513.BBNG_00536 2e-109 401.7 Bifidobacteriales Bacteria 2AVVG@1,2INFG@201174,31MP9@2,4D12J@85004 NA|NA|NA LPKNPDNH_01140 702459.BBPR_0619 1.9e-220 771.5 Bifidobacteriales ctpE GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 ko:K12952 ko00000,ko01000 3.A.3.23 Bacteria 2GJJC@201174,4CYS1@85004,COG0474@1,COG0474@2 NA|NA|NA P E1-E2 ATPase LPKNPDNH_01141 702459.BBPR_0619 3.9e-232 810.4 Bifidobacteriales ctpE GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 ko:K12952 ko00000,ko01000 3.A.3.23 Bacteria 2GJJC@201174,4CYS1@85004,COG0474@1,COG0474@2 NA|NA|NA P E1-E2 ATPase LPKNPDNH_01142 702459.BBPR_0620 0.0 1817.4 Bifidobacteriales acnA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GJD5@201174,4CZ3T@85004,COG1048@1,COG1048@2 NA|NA|NA C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate LPKNPDNH_01144 398513.BBNG_00539 1.1e-166 592.4 Bifidobacteriales gmk 1.1.1.23,2.7.4.8 ko:K00013,ko:K00942 ko00230,ko00340,ko01100,ko01110,ko01230,map00230,map00340,map01100,map01110,map01230 M00026,M00050 R00332,R01158,R01163,R02090,R03012 RC00002,RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN40@201174,4CZPZ@85004,COG2852@1,COG2852@2 NA|NA|NA S Protein conserved in bacteria LPKNPDNH_01145 398513.BBNG_00540 0.0 1186.8 Bifidobacteriales ilvD GO:0003674,GO:0003824,GO:0004160,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1259,iECIAI39_1322.ECIAI39_3015 Bacteria 2GJIJ@201174,4CZ1T@85004,COG0129@1,COG0129@2 NA|NA|NA H Belongs to the IlvD Edd family LPKNPDNH_01146 398513.BBNG_00541 1.1e-53 215.7 Bifidobacteriales rpoZ GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 2IQHU@201174,4D12C@85004,COG1758@1,COG1758@2 NA|NA|NA K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits LPKNPDNH_01147 398513.BBNG_00542 9.4e-220 769.2 Bifidobacteriales metK GO:0000096,GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006556,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009069,GO:0009108,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0019752,GO:0019899,GO:0030312,GO:0030554,GO:0030955,GO:0031420,GO:0032553,GO:0032555,GO:0032559,GO:0033353,GO:0034641,GO:0035375,GO:0035639,GO:0036094,GO:0040007,GO:0042278,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046872,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901605,GO:1901657 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 iJN678.metX,iJN746.PP_4967,iYL1228.KPN_03375 Bacteria 2GJ4U@201174,4CZ5D@85004,COG0192@1,COG0192@2 NA|NA|NA H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme LPKNPDNH_01148 702459.BBPR_0626 0.0 1470.7 Bifidobacteriales priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GKES@201174,4D04J@85004,COG1198@1,COG1198@2 NA|NA|NA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA LPKNPDNH_01149 398513.BBNG_00545 3.2e-135 487.6 Bifidobacteriales 3.8.1.2 ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 R05287 RC00697 ko00000,ko00001,ko01000 Bacteria 2I8XE@201174,4CZGV@85004,COG1011@1,COG1011@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase LPKNPDNH_01150 398513.BBNG_00546 4.3e-183 647.1 Bifidobacteriales fmt GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.1.176,2.1.2.9 ko:K00604,ko:K03500 ko00670,ko00970,map00670,map00970 R03940 RC00026,RC00165 ko00000,ko00001,ko01000,ko03009 iECABU_c1320.ECABU_c37050,iECUMN_1333.ECUMN_3761,ic_1306.c4048 Bacteria 2GKH5@201174,4CZ8C@85004,COG0223@1,COG0223@2 NA|NA|NA J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus LPKNPDNH_01151 398513.BBNG_00547 4.7e-137 493.8 Bifidobacteriales serB 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 Bacteria 2GJDH@201174,4CYWC@85004,COG0560@1,COG0560@2 NA|NA|NA E haloacid dehalogenase-like hydrolase LPKNPDNH_01152 702459.BBPR_0630 0.0 1081.2 Bifidobacteriales arc GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 ko:K13525,ko:K13527 ko03050,ko04141,ko05134,map03050,map04141,map05134 M00342,M00400,M00403 ko00000,ko00001,ko00002,ko03019,ko03051,ko04131,ko04147 3.A.16.1 Bacteria 2GMR1@201174,4CZ86@85004,COG1222@1,COG1222@2 NA|NA|NA O AAA ATPase forming ring-shaped complexes LPKNPDNH_01153 702459.BBPR_0631 0.0 1094.0 Bifidobacteriales dop GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119,6.3.1.19 ko:K13571,ko:K20814 M00342 R11207 RC00090,RC00096 ko00000,ko00002,ko01000,ko03051 Bacteria 2GJGI@201174,4CZAN@85004,COG4122@1,COG4122@2 NA|NA|NA S Pup-ligase protein LPKNPDNH_01154 398513.BBNG_00550 2.4e-158 564.7 Bifidobacteriales hisN 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 2HGP2@201174,4CYWZ@85004,COG0483@1,COG0483@2 NA|NA|NA G Inositol monophosphatase family LPKNPDNH_01155 398513.BBNG_00551 1.6e-10 71.6 Bifidobacteriales pup ko:K13570 ko00000,ko04121 Bacteria 2B5FT@1,2GV5R@201174,31YAF@2,4D1NH@85004 NA|NA|NA S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation LPKNPDNH_01156 702459.BBPR_0634 8.5e-276 955.7 Bifidobacteriales pafA GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 ko:K13571 M00342 R11207 RC00090,RC00096 ko00000,ko00002,ko01000,ko03051 Bacteria 2GMC6@201174,4CZ12@85004,COG0638@1,COG0638@2 NA|NA|NA O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine LPKNPDNH_01157 398513.BBNG_00553 8.1e-42 176.0 Bifidobacteriales hup GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 ko:K03530 ko00000,ko03032,ko03036,ko03400 Bacteria 2IKQR@201174,4D11V@85004,COG0776@1,COG0776@2 NA|NA|NA L Belongs to the bacterial histone-like protein family LPKNPDNH_01158 702459.BBPR_0636 0.0 1576.2 Bifidobacteriales Bacteria 2GMAV@201174,4CYRT@85004,COG0392@1,COG0392@2 NA|NA|NA S Lysylphosphatidylglycerol synthase TM region LPKNPDNH_01159 702459.BBPR_0637 3e-281 973.8 Bifidobacteriales purB GO:0003674,GO:0003824,GO:0004018,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 iAF1260.b1131,iBWG_1329.BWG_0979,iE2348C_1286.E2348C_1272,iEC042_1314.EC042_1202,iECABU_c1320.ECABU_c13450,iECDH10B_1368.ECDH10B_1203,iECP_1309.ECP_1126,iECUMN_1333.ECUMN_1375,iETEC_1333.ETEC_1255,iEcHS_1320.EcHS_A1251,iEcolC_1368.EcolC_2472,iJO1366.b1131,iJR904.b1131,iLF82_1304.LF82_1774,iNRG857_1313.NRG857_05460,iY75_1357.Y75_RS05905,ic_1306.c1510 Bacteria 2GM71@201174,4CYV6@85004,COG0015@1,COG0015@2 NA|NA|NA F Adenylosuccinate lyase C-terminal LPKNPDNH_01160 702459.BBPR_0638 4.4e-291 1006.5 Bifidobacteriales Bacteria 2IHFB@201174,4CZ17@85004,COG1075@1,COG1075@2 NA|NA|NA S PGAP1-like protein LPKNPDNH_01162 702459.BBPR_0641 2.7e-74 285.0 Bifidobacteriales Bacteria 2BG6D@1,2IR67@201174,32A37@2,4D18W@85004 NA|NA|NA LPKNPDNH_01163 398513.BBNG_00559 1.6e-148 532.3 Bifidobacteriales ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2GJMP@201174,4CZ8P@85004,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor (vWF) type A domain LPKNPDNH_01164 702459.BBPR_0643 6.8e-190 669.8 Bifidobacteriales ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 2I9VM@201174,4CZ00@85004,COG2304@1,COG2304@2 NA|NA|NA S von Willebrand factor (vWF) type A domain LPKNPDNH_01165 702459.BBPR_0644 6.4e-94 350.1 Bifidobacteriales Bacteria 2AUTC@1,2IKRN@201174,31KGE@2,4D134@85004 NA|NA|NA LPKNPDNH_01166 398513.BBNG_00562 1.5e-175 622.1 Bifidobacteriales Bacteria 2GKSJ@201174,4CYYD@85004,COG1721@1,COG1721@2 NA|NA|NA S Protein of unknown function DUF58 LPKNPDNH_01167 702459.BBPR_0646 5e-196 690.3 Bifidobacteriales moxR ko:K03924 ko00000,ko01000 Bacteria 2GK07@201174,4CZ2I@85004,COG0714@1,COG0714@2 NA|NA|NA S ATPase family associated with various cellular activities (AAA) LPKNPDNH_01168 702459.BBPR_0647 4.4e-143 513.8 Bifidobacteriales ung GO:0003674,GO:0003824,GO:0004844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJ9Z@201174,4CZ3Y@85004,COG0692@1,COG0692@2 NA|NA|NA L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine LPKNPDNH_01169 398513.BBNG_00565 9.9e-71 273.5 Bifidobacteriales Bacteria 2DP6P@1,2GQYA@201174,330SA@2,4CZYT@85004 NA|NA|NA S LytR cell envelope-related transcriptional attenuator LPKNPDNH_01170 398513.BBNG_00566 2.2e-44 184.5 Bifidobacteriales cspA ko:K03704 ko00000,ko03000 Bacteria 2GQRU@201174,4D1FB@85004,COG1278@1,COG1278@2 NA|NA|NA K 'Cold-shock' DNA-binding domain LPKNPDNH_01171 398513.BBNG_00568 2.7e-291 1007.3 Bifidobacteriales groL GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016020,GO:0016465,GO:0022610,GO:0030112,GO:0030312,GO:0030313,GO:0031975,GO:0032991,GO:0036293,GO:0040007,GO:0042026,GO:0042603,GO:0043388,GO:0044093,GO:0044183,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051704,GO:0061077,GO:0065007,GO:0065009,GO:0070482,GO:0071944,GO:0101031,GO:1990220,GO:2000677,GO:2000679 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 2GKC9@201174,4CZJK@85004,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions LPKNPDNH_01172 398513.BBNG_00569 1.7e-10 72.0 Bifidobacteriales Bacteria 2GQI8@201174,4D17K@85004,COG4842@1,COG4842@2 NA|NA|NA S Proteins of 100 residues with WXG LPKNPDNH_01173 702459.BBPR_0652 1.2e-173 615.9 Bifidobacteriales Bacteria 2B59T@1,2HZNR@201174,31Y3Y@2,4D12Q@85004 NA|NA|NA LPKNPDNH_01174 398513.BBNG_00571 1.6e-134 485.3 Bifidobacteriales Bacteria 2GIZB@201174,4CYPS@85004,COG0745@1,COG0745@2 NA|NA|NA KT Response regulator receiver domain protein LPKNPDNH_01175 398513.BBNG_00572 0.0 1089.7 Bifidobacteriales 2.7.13.3 ko:K02484,ko:K07653,ko:K07768 ko02020,map02020 M00443,M00460 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 2I2DU@201174,4CZNF@85004,COG3850@1,COG3850@2,COG5002@1,COG5002@2 NA|NA|NA T ATPase histidine kinase DNA gyrase B HSP90 domain protein LPKNPDNH_01176 398513.BBNG_00573 3.8e-66 257.3 Bifidobacteriales cspB ko:K03704 ko00000,ko03000 Bacteria 2IKXN@201174,4D0V4@85004,COG1278@1,COG1278@2 NA|NA|NA K 'Cold-shock' DNA-binding domain LPKNPDNH_01177 398513.BBNG_00574 9.5e-192 676.0 Bifidobacteriales Bacteria 28NWB@1,2GJ74@201174,2ZBU7@2,4CYW9@85004 NA|NA|NA S Protein of unknown function (DUF3027) LPKNPDNH_01178 702459.BBPR_0657 4.7e-185 653.7 Bifidobacteriales uspA Bacteria 2IA7S@201174,4CZZ0@85004,COG0589@1,COG0589@2 NA|NA|NA T Belongs to the universal stress protein A family LPKNPDNH_01179 398513.BBNG_00576 0.0 1588.2 Bifidobacteriales clpC ko:K03696 ko01100,map01100 ko00000,ko03110 Bacteria 2GJ77@201174,4CZCH@85004,COG0542@1,COG0542@2 NA|NA|NA O ATPase family associated with various cellular activities (AAA) LPKNPDNH_01183 398513.BBNG_00580 7.7e-33 146.0 Bifidobacteriales 3.1.26.12,3.2.1.8 ko:K01181,ko:K08300,ko:K08301 ko03018,map03018 M00394 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Bacteria 2I2EC@201174,4CYYM@85004,COG3266@1,COG3266@2 NA|NA|NA S Domain of Unknown Function (DUF349) LPKNPDNH_01184 398513.BBNG_00580 1.7e-153 548.9 Bifidobacteriales 3.1.26.12,3.2.1.8 ko:K01181,ko:K08300,ko:K08301 ko03018,map03018 M00394 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Bacteria 2I2EC@201174,4CYYM@85004,COG3266@1,COG3266@2 NA|NA|NA S Domain of Unknown Function (DUF349) LPKNPDNH_01185 398513.BBNG_00581 8.7e-262 909.1 Bifidobacteriales hisS 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GIYJ@201174,4CYR9@85004,COG0124@1,COG0124@2 NA|NA|NA J Histidyl-tRNA synthetase LPKNPDNH_01186 702459.BBPR_0665 0.0 1203.3 Bifidobacteriales aspS GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 2GJHU@201174,4CYWQ@85004,COG0173@1,COG0173@2 NA|NA|NA J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) LPKNPDNH_01187 702459.BBPR_0666 1.4e-63 248.8 Bifidobacteriales Bacteria 2ISMU@201174,4D1AF@85004,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon LPKNPDNH_01188 702459.BBPR_0667 8.2e-93 346.3 Bifidobacteriales ko:K03976,ko:K19055 ko00000,ko01000,ko03016 Bacteria 2GKUX@201174,4D0MH@85004,COG2606@1,COG2606@2 NA|NA|NA S Aminoacyl-tRNA editing domain LPKNPDNH_01189 398513.BBNG_00587 3.9e-139 500.7 Bifidobacteriales gluA 3.6.3.21 ko:K02028,ko:K10008 ko02010,map02010 M00233,M00236 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.9 Bacteria 2GIZW@201174,4CYXE@85004,COG1126@1,COG1126@2 NA|NA|NA E ATP-binding protein of ABC transporter for glutamate K02028 LPKNPDNH_01190 398513.BBNG_00588 1.2e-146 525.8 Bifidobacteriales gluB ko:K10005 ko02010,map02010 M00233 ko00000,ko00001,ko00002,ko02000 3.A.1.3.9 Bacteria 2GJH8@201174,4CZA4@85004,COG0834@1,COG0834@2 NA|NA|NA ET Belongs to the bacterial solute-binding protein 3 family LPKNPDNH_01191 702459.BBPR_0670 1.8e-111 408.7 Bifidobacteriales gluC GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 ko:K10006,ko:K10040 ko02010,map02010 M00228,M00233 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.9 Bacteria 2GNUR@201174,4CZ5M@85004,COG0765@1,COG0765@2 NA|NA|NA E Binding-protein-dependent transport system inner membrane component LPKNPDNH_01192 702459.BBPR_0671 1.5e-197 695.3 Bifidobacteriales gluD ko:K02029,ko:K10007 ko02010,map02010 M00233,M00236 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.9 Bacteria 2GNBH@201174,4CZB4@85004,COG0765@1,COG0765@2 NA|NA|NA E Binding-protein-dependent transport system inner membrane component LPKNPDNH_01193 702459.BBPR_0672 6e-194 683.3 Bifidobacteriales 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 2GKRN@201174,4CZZU@85004,COG2326@1,COG2326@2 NA|NA|NA S Polyphosphate kinase 2 (PPK2) LPKNPDNH_01194 398513.BBNG_00592 0.0 1693.7 Bifidobacteriales Bacteria 2GJSV@201174,4CZVX@85004,COG4581@1,COG4581@2 NA|NA|NA L DEAD DEAH box helicase LPKNPDNH_01195 398513.BBNG_00593 5.5e-256 889.8 Bifidobacteriales rarA ko:K07478 ko00000 Bacteria 2GKDP@201174,4CZ2K@85004,COG2256@1,COG2256@2 NA|NA|NA L Recombination factor protein RarA LPKNPDNH_01197 398513.BBNG_00594 5.2e-257 893.3 Bifidobacteriales ko:K18926 M00715 ko00000,ko00002,ko02000 2.A.1.3.30 Bacteria 2GIZX@201174,4CZ0R@85004,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily LPKNPDNH_01198 398513.BBNG_00595 0.0 1437.9 Bifidobacteriales ecfA ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2I2G4@201174,4CZJE@85004,COG0619@1,COG0619@2,COG1129@1,COG1129@2 NA|NA|NA GP ABC transporter, ATP-binding protein LPKNPDNH_01199 398513.BBNG_00596 1.1e-104 386.0 Bifidobacteriales ribU GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 Bacteria 2IAX0@201174,4CZQD@85004,COG3601@1,COG3601@2 NA|NA|NA U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins LPKNPDNH_01201 398513.BBNG_00598 1.3e-139 502.3 Bifidobacteriales ppgK 2.7.1.2,2.7.1.63 ko:K00845,ko:K00886 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786,R02187,R02189 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJA0@201174,4CYR1@85004,COG1940@1,COG1940@2 NA|NA|NA GK ROK family LPKNPDNH_01202 398513.BBNG_00599 2e-213 748.0 Bifidobacteriales Bacteria 2GNMB@201174,4CZ48@85004,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase class I and II LPKNPDNH_01203 702459.BBPR_0681 3.4e-138 497.7 Bifidobacteriales bioM ko:K16784,ko:K16786 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 2I9PF@201174,4D04S@85004,COG1122@1,COG1122@2 NA|NA|NA P ATPases associated with a variety of cellular activities LPKNPDNH_01204 762211.BSTEL_1724 8.2e-72 276.6 Bifidobacteriales 2.8.2.22 ko:K01023 ko00000,ko01000 Bacteria 2A5FI@1,2I8X3@201174,30U5H@2,4D09F@85004 NA|NA|NA S Arylsulfotransferase Ig-like domain LPKNPDNH_01205 702459.BBPR_0683 0.0 1427.5 Bifidobacteriales Bacteria 2GNXR@201174,4CZXK@85004,COG1807@1,COG1807@2 NA|NA|NA M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family LPKNPDNH_01206 702459.BBPR_0684 0.0 2204.1 Bifidobacteriales Bacteria 2GWSR@201174,4CZ33@85004,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat LPKNPDNH_01207 398513.BBNG_00604 0.0 1784.6 Bifidobacteriales ligA GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 2GJUY@201174,4CZBC@85004,COG0272@1,COG0272@2 NA|NA|NA L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA LPKNPDNH_01208 702459.BBPR_0686 6.3e-210 736.5 Bifidobacteriales mrp GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0040007,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K03593 ko00000,ko03029,ko03036 Bacteria 2GJUZ@201174,4CZDC@85004,COG0489@1,COG0489@2 NA|NA|NA D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP LPKNPDNH_01209 702459.BBPR_0687 7.5e-160 569.7 Bifidobacteriales gmk 1.1.1.23,2.7.4.8 ko:K00013,ko:K00942 ko00230,ko00340,ko01100,ko01110,ko01230,map00230,map00340,map01100,map01110,map01230 M00026,M00050 R00332,R01158,R01163,R02090,R03012 RC00002,RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 Bacteria 2I2HQ@201174,4D00A@85004,COG2852@1,COG2852@2 NA|NA|NA S Protein conserved in bacteria LPKNPDNH_01212 1680.BADO_1259 5.1e-19 100.9 Bifidobacteriales Bacteria 2AD62@1,2HCXF@201174,312US@2,4D2KS@85004 NA|NA|NA LPKNPDNH_01214 1688.BCUN_0913 1.3e-18 98.6 Bifidobacteriales Bacteria 2AVGA@1,2IMUF@201174,31M8G@2,4D13I@85004 NA|NA|NA LPKNPDNH_01215 398513.BBNG_00618 1.8e-286 991.1 Bifidobacteriales glnA GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 2GMN1@201174,4CZNK@85004,COG0174@1,COG0174@2 NA|NA|NA E glutamine synthetase LPKNPDNH_01216 702459.BBPR_0689 9.4e-144 516.2 Bifidobacteriales Bacteria 2AUFS@1,2I87Z@201174,2ZBYU@2,4CYT8@85004 NA|NA|NA S Domain of unknown function (DUF4191) LPKNPDNH_01217 702459.BBPR_0690 5.2e-281 973.0 Bifidobacteriales lpdA 1.16.1.1,1.8.1.4 ko:K00382,ko:K00520 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GIXY@201174,4CZEI@85004,COG1249@1,COG1249@2 NA|NA|NA C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family LPKNPDNH_01218 398513.BBNG_00621 5.5e-104 383.6 Bifidobacteriales GO:0008150,GO:0009605,GO:0009607,GO:0020012,GO:0030682,GO:0042783,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 Bacteria 2AN86@1,2HWWU@201174,31D67@2,4CZZS@85004 NA|NA|NA S Protein of unknown function (DUF3043) LPKNPDNH_01219 398513.BBNG_00622 3e-259 900.6 Bifidobacteriales argE Bacteria 2GM84@201174,4CYZT@85004,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain LPKNPDNH_01220 398513.BBNG_00623 2.2e-191 674.9 Bifidobacteriales Bacteria 2I9EN@201174,4D025@85004,COG3023@1,COG3023@2 NA|NA|NA V N-Acetylmuramoyl-L-alanine amidase LPKNPDNH_01221 702459.BBPR_0694 3.2e-147 527.7 Bifidobacteriales ytrE ko:K02003,ko:K09810,ko:K10038 ko02010,map02010 M00227,M00255,M00258 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.125,3.A.1.3.2 Bacteria 2ICH8@201174,4CZF8@85004,COG1136@1,COG1136@2 NA|NA|NA V ATPases associated with a variety of cellular activities LPKNPDNH_01222 702459.BBPR_0695 3.8e-196 690.6 Bifidobacteriales Bacteria 2C746@1,2I2G8@201174,340R4@2,4CZHI@85004 NA|NA|NA LPKNPDNH_01223 702459.BBPR_0696 2.3e-232 811.2 Bifidobacteriales ybbD 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM43@201174,4CZ6R@85004,COG1472@1,COG1472@2 NA|NA|NA G Glycosyl hydrolase family 3 N-terminal domain protein LPKNPDNH_01224 702459.BBPR_0697 0.0 1956.4 Bifidobacteriales GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K09118 ko00000 Bacteria 2GMP3@201174,4CYW1@85004,COG1615@1,COG1615@2 NA|NA|NA S Uncharacterised protein family (UPF0182) LPKNPDNH_01225 702459.BBPR_0698 4e-206 723.8 Bifidobacteriales tagB 2.7.8.14,2.7.8.44,2.7.8.47 ko:K18704,ko:K21285 R11558,R11614,R11621 RC00078 ko00000,ko01000 iYO844.BSU35760 Bacteria 2GMXY@201174,4D1XX@85004,COG1887@1,COG1887@2 NA|NA|NA M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase LPKNPDNH_01226 702459.BBPR_0699 0.0 1259.6 Bifidobacteriales 2.7.8.14,2.7.8.47 ko:K18704 R11614,R11621 ko00000,ko01000 Bacteria 2I9SV@201174,4D24D@85004,COG1887@1,COG1887@2 NA|NA|NA M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase LPKNPDNH_01227 398513.BBNG_00630 1e-218 765.8 Bacteria ko:K13663 ko00000,ko01000 Bacteria COG1835@1,COG1835@2 NA|NA|NA I transferase activity, transferring acyl groups other than amino-acyl groups LPKNPDNH_01230 398513.BBNG_00633 5e-128 463.8 Bifidobacteriales ispD GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60,4.6.1.12 ko:K00991,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633,R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNHP@201174,4CYVZ@85004,COG1211@1,COG1211@2 NA|NA|NA I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) LPKNPDNH_01231 398513.BBNG_00634 1.9e-197 694.9 Bifidobacteriales Bacteria 2IH1R@201174,4D0MJ@85004,COG0451@1,COG0451@2 NA|NA|NA GM GDP-mannose 4,6 dehydratase LPKNPDNH_01232 702459.BBPR_0704 1e-150 539.3 Bifidobacteriales ko:K01992,ko:K09690,ko:K09692 ko02010,map02010 M00250,M00251,M00254 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.103,3.A.1.104 Bacteria 2HZUN@201174,4D1UK@85004,COG1682@1,COG1682@2 NA|NA|NA GM ABC-2 type transporter LPKNPDNH_01233 398513.BBNG_00636 4.9e-145 520.4 Bifidobacteriales tagH GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0015921,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:1901264,GO:1901505 3.6.3.38,3.6.3.40 ko:K09689,ko:K09693 ko02010,map02010 M00249,M00251 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.101,3.A.1.104 Bacteria 2GIVF@201174,4D1YJ@85004,COG1134@1,COG1134@2 NA|NA|NA GM ABC transporter LPKNPDNH_01234 398513.BBNG_00637 1.7e-96 358.6 Bifidobacteriales 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 Bacteria 2HZCB@201174,4CZQI@85004,COG1247@1,COG1247@2 NA|NA|NA M Acetyltransferase (GNAT) domain LPKNPDNH_01235 398513.BBNG_00638 7.6e-114 416.4 Bifidobacteriales pth GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 ko00000,ko01000,ko03012 Bacteria 2GKCV@201174,4CZBE@85004,COG0193@1,COG0193@2 NA|NA|NA J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis LPKNPDNH_01236 398513.BBNG_00639 0.0 2328.9 Bifidobacteriales mfd ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJ42@201174,4CZ8X@85004,COG1197@1,COG1197@2 NA|NA|NA L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site LPKNPDNH_01237 702459.BBPR_0709 1.8e-297 1027.7 Bifidobacteriales pabB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.85,4.1.3.27,4.1.3.38 ko:K01657,ko:K01665,ko:K03342,ko:K13503,ko:K13950 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716,R05553 RC00010,RC01418,RC01843,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000,ko01007 iEC042_1314.EC042_1977 Bacteria 2GKJT@201174,4D20E@85004,COG0147@1,COG0147@2 NA|NA|NA EH chorismate binding enzyme LPKNPDNH_01238 398513.BBNG_00641 6.4e-153 546.6 Bacteria pabC 2.6.1.42,2.6.1.85,4.1.3.38 ko:K00826,ko:K01665,ko:K02619,ko:K03342 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R01716,R02199,R05553,R10991 RC00006,RC00010,RC00036,RC01418,RC01843,RC02148 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria COG0115@1,COG0115@2 NA|NA|NA E branched-chain-amino-acid transaminase activity LPKNPDNH_01239 398513.BBNG_00642 6.9e-245 852.8 Bifidobacteriales eno 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Bacteria 2GJAY@201174,4CYT3@85004,COG0148@1,COG0148@2 NA|NA|NA G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis LPKNPDNH_01240 398513.BBNG_00643 2.5e-101 374.8 Bifidobacteriales divIC ko:K05589,ko:K13052 ko00000,ko03036 Bacteria 2IR5G@201174,4D0SS@85004,COG2919@1,COG2919@2 NA|NA|NA D Septum formation initiator LPKNPDNH_01241 398513.BBNG_00644 5.7e-106 390.2 Bifidobacteriales ppx2 3.6.1.11,3.6.1.40 ko:K01524,ko:K09009 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 2I8CS@201174,4CZQX@85004,COG1507@1,COG1507@2 NA|NA|NA S Protein of unknown function (DUF501) LPKNPDNH_01242 702459.BBPR_0714 1e-119 436.0 Bifidobacteriales ppx GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 2GJBN@201174,4CZCS@85004,COG0248@1,COG0248@2 NA|NA|NA FP Ppx/GppA phosphatase family LPKNPDNH_01243 398513.BBNG_00645 2.1e-54 218.0 Bifidobacteriales ppx GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 2GJBN@201174,4CZCS@85004,COG0248@1,COG0248@2 NA|NA|NA FP Ppx/GppA phosphatase family LPKNPDNH_01245 398513.BBNG_00646 1e-96 359.4 Bifidobacteriales Bacteria 2ASIR@1,2IHD9@201174,31HZA@2,4D0QP@85004 NA|NA|NA LPKNPDNH_01246 702459.BBPR_0716 6.1e-282 976.1 Bifidobacteriales sdaA 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 Bacteria 2GJPA@201174,4CZ6I@85004,COG1760@1,COG1760@2 NA|NA|NA E Serine dehydratase alpha chain LPKNPDNH_01247 398513.BBNG_00648 2.2e-72 278.1 Bifidobacteriales fkbP 5.2.1.8 ko:K01802 ko00000,ko01000 Bacteria 2GJK2@201174,4D0V6@85004,COG0545@1,COG0545@2 NA|NA|NA G Peptidyl-prolyl cis-trans LPKNPDNH_01248 398513.BBNG_00649 7.5e-80 303.1 Bifidobacteriales greA GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0032774,GO:0032784,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 ko:K03624 ko00000,ko03021 Bacteria 2GNZV@201174,4D0QM@85004,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides LPKNPDNH_01250 702459.BBPR_0720 1e-107 396.0 Bifidobacteriales Bacteria 2AVVF@1,2INFF@201174,31MP8@2,4D167@85004 NA|NA|NA LPKNPDNH_01251 702459.BBPR_0721 1.1e-140 506.1 Bifidobacteriales yplQ ko:K11068 ko00000,ko02042 Bacteria 2GJGQ@201174,4CZGT@85004,COG1272@1,COG1272@2 NA|NA|NA S Haemolysin-III related LPKNPDNH_01252 398513.BBNG_00651 4.7e-285 986.5 Bifidobacteriales pdtaS GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 ko:K00936 M00839 ko00000,ko00002,ko01000,ko01001,ko02022 Bacteria 2GKMP@201174,4CYV1@85004,COG3920@1,COG3920@2 NA|NA|NA T ATPase histidine kinase DNA gyrase B HSP90 domain protein LPKNPDNH_01253 398513.BBNG_00652 1.9e-46 191.4 Bifidobacteriales whiB GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K18955 ko00000,ko03000 Bacteria 2DMIE@1,2IQCG@201174,32RSG@2,4D11W@85004 NA|NA|NA K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA LPKNPDNH_01254 398513.BBNG_00653 0.0 1192.2 Bifidobacteriales ko:K03466 ko00000,ko03036 3.A.12 Bacteria 2GJBR@201174,4CYU3@85004,COG1674@1,COG1674@2 NA|NA|NA D FtsK/SpoIIIE family LPKNPDNH_01255 398513.BBNG_00654 2.4e-270 937.6 Bifidobacteriales Bacteria 2GJJJ@201174,4CYQY@85004,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-related transcriptional attenuator domain LPKNPDNH_01256 398513.BBNG_00656 5.8e-54 216.5 Bifidobacteriales whiB ko:K18955 ko00000,ko03000 Bacteria 2CC1Y@1,2IQ4Q@201174,32RUK@2,4D12I@85004 NA|NA|NA K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA LPKNPDNH_01257 398513.BBNG_00657 0.0 1996.5 Bifidobacteriales Bacteria 2I2FX@201174,4CYVM@85004,COG1216@1,COG1216@2,COG5617@1,COG5617@2 NA|NA|NA S Glycosyl transferase, family 2 LPKNPDNH_01258 398513.BBNG_00658 2.2e-266 924.5 Bifidobacteriales Bacteria 2DNQG@1,2I2FY@201174,32YJZ@2,4CZE9@85004 NA|NA|NA LPKNPDNH_01259 702459.BBPR_0729 6.3e-66 256.5 Bifidobacteriales MA20_43655 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 Bacteria 2IS6W@201174,4D0YK@85004,COG3824@1,COG3824@2 NA|NA|NA S Zincin-like metallopeptidase LPKNPDNH_01260 702459.BBPR_0730 5e-156 557.0 Bifidobacteriales cof 5.2.1.8 ko:K01802 ko00000,ko01000 Bacteria 2HZD0@201174,4CZ4N@85004,COG0561@1,COG0561@2 NA|NA|NA T Eukaryotic phosphomannomutase LPKNPDNH_01261 702459.BBPR_0731 9.2e-130 469.5 Bifidobacteriales ctsW ko:K02242 M00429 ko00000,ko00002,ko02044 Bacteria 2I9PA@201174,4D11A@85004,COG1040@1,COG1040@2 NA|NA|NA S Phosphoribosyl transferase domain LPKNPDNH_01262 398513.BBNG_00662 8.1e-72 276.2 Bifidobacteriales rulA 3.4.21.88 ko:K01356,ko:K03503 M00729 ko00000,ko00002,ko01000,ko01002,ko03400 Bacteria 2GPJI@201174,4D0WP@85004,COG1974@1,COG1974@2 NA|NA|NA KT Peptidase S24-like LPKNPDNH_01263 702459.BBPR_0733 1.1e-203 715.7 Bifidobacteriales Bacteria 2GIX7@201174,4CZNA@85004,COG5002@1,COG5002@2 NA|NA|NA T ATPase histidine kinase DNA gyrase B HSP90 domain protein LPKNPDNH_01264 398513.BBNG_00664 1.9e-127 461.8 Bifidobacteriales Bacteria 2GJE6@201174,4CZS5@85004,COG0745@1,COG0745@2 NA|NA|NA T Response regulator receiver domain protein LPKNPDNH_01265 398513.BBNG_00665 0.0 1568.9 Bifidobacteriales glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 ko00000,ko00001,ko00002,ko01000,ko04147 CBM48,GH13 Bacteria 2GJ5C@201174,4CZMD@85004,COG0296@1,COG0296@2 NA|NA|NA G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position LPKNPDNH_01266 398513.BBNG_00666 5.1e-102 377.1 Bifidobacteriales carD GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 ko:K07736 ko00000,ko03000 Bacteria 2GKSU@201174,4CZXD@85004,COG1329@1,COG1329@2 NA|NA|NA K CarD-like/TRCF domain LPKNPDNH_01267 398513.BBNG_00667 4.2e-83 313.9 Bifidobacteriales ispF GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008685,GO:0009058,GO:0009987,GO:0016114,GO:0016829,GO:0016849,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0051483,GO:0071704,GO:1901576 2.1.1.228,2.7.7.60,4.6.1.12 ko:K00554,ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05633,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 iNJ661.Rv3581c Bacteria 2II8H@201174,4D0X6@85004,COG0245@1,COG0245@2 NA|NA|NA H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) LPKNPDNH_01268 398513.BBNG_00668 4.3e-139 500.7 Bifidobacteriales znuB ko:K02075,ko:K09816 ko02010,map02010 M00242,M00244 ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 Bacteria 2GJ7H@201174,4CYTG@85004,COG1108@1,COG1108@2 NA|NA|NA U ABC 3 transport family LPKNPDNH_01269 398513.BBNG_00669 1.8e-164 585.1 Bifidobacteriales znuC ko:K02074,ko:K09817 ko02010,map02010 M00242,M00244 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 Bacteria 2GP3A@201174,4CZEV@85004,COG1121@1,COG1121@2 NA|NA|NA P ATPases associated with a variety of cellular activities LPKNPDNH_01270 702459.BBPR_0740 9.6e-173 612.8 Bifidobacteriales ko:K02077 M00244 ko00000,ko00002,ko02000 3.A.1.15 Bacteria 2GM1K@201174,4CZ99@85004,COG0803@1,COG0803@2 NA|NA|NA P Zinc-uptake complex component A periplasmic LPKNPDNH_01271 398513.BBNG_00671 2e-163 581.6 Bifidobacteriales folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJZS@201174,4CZ53@85004,COG0190@1,COG0190@2 NA|NA|NA F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate LPKNPDNH_01272 398513.BBNG_00672 6.8e-241 839.7 Bifidobacteriales rpsA ko:K02945 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GJAK@201174,4CZ6S@85004,COG0539@1,COG0539@2 NA|NA|NA J Ribosomal protein S1 LPKNPDNH_01273 398513.BBNG_00674 4.5e-106 390.6 Bifidobacteriales coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN96@201174,4D0PG@85004,COG0237@1,COG0237@2 NA|NA|NA H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A LPKNPDNH_01274 702459.BBPR_0745 0.0 1378.6 Bifidobacteriales uvrB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K03702,ko:K08999 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2GJ03@201174,4CZR0@85004,COG0556@1,COG0556@2 NA|NA|NA L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage LPKNPDNH_01275 398513.BBNG_00676 2.3e-102 378.3 Bifidobacteriales terC ko:K05794 ko00000 Bacteria 2GIWU@201174,4CYW2@85004,COG0861@1,COG0861@2 NA|NA|NA P Integral membrane protein, TerC family LPKNPDNH_01276 398513.BBNG_00677 1.9e-272 944.5 Bifidobacteriales pyk GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 e_coli_core.b1854,iAF1260.b1854,iB21_1397.B21_01813,iBWG_1329.BWG_1668,iEC042_1314.EC042_2021,iECBD_1354.ECBD_1784,iECB_1328.ECB_01825,iECDH10B_1368.ECDH10B_1995,iECDH1ME8569_1439.ECDH1ME8569_1801,iECD_1391.ECD_01825,iECO103_1326.ECO103_2044,iECO111_1330.ECO111_2362,iECO26_1355.ECO26_2692,iECUMN_1333.ECUMN_2152,iETEC_1333.ETEC_1887,iEcDH1_1363.EcDH1_1786,iEcE24377_1341.EcE24377A_2084,iEcHS_1320.EcHS_A1947,iEcSMS35_1347.EcSMS35_1332,iEcolC_1368.EcolC_1778,iG2583_1286.G2583_2306,iJO1366.b1854,iJR904.b1854,iSBO_1134.SBO_1162,iSSON_1240.SSON_1294,iSbBS512_1146.SbBS512_E2130,iUMNK88_1353.UMNK88_2326,iY75_1357.Y75_RS09740 Bacteria 2GJY8@201174,4CZA8@85004,COG0469@1,COG0469@2 NA|NA|NA G Pyruvate kinase LPKNPDNH_01277 398513.BBNG_00678 3.3e-109 401.0 Bifidobacteriales aspA 3.6.1.13 ko:K01515 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000 Bacteria 2HEH8@201174,4CZD0@85004,COG0494@1,COG0494@2 NA|NA|NA L NUDIX domain LPKNPDNH_01279 398513.BBNG_00679 9.2e-120 436.4 Bifidobacteriales pdtaR GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944 ko:K22010 M00839 ko00000,ko00002,ko02022 Bacteria 2GK7T@201174,4CYS7@85004,COG3707@1,COG3707@2 NA|NA|NA T Response regulator receiver domain protein LPKNPDNH_01280 398513.BBNG_00680 0.0 1840.9 Bifidobacteriales polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 2GJY2@201174,4CYVK@85004,COG0258@1,COG0258@2,COG0749@1,COG0749@2 NA|NA|NA L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity LPKNPDNH_01281 398513.BBNG_00681 2.9e-173 614.4 Bifidobacteriales yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.4.16 ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKHZ@201174,4CYXC@85004,COG0327@1,COG0327@2 NA|NA|NA L NIF3 (NGG1p interacting factor 3) LPKNPDNH_01282 702459.BBPR_0752 1.2e-118 432.6 Bifidobacteriales 3.6.1.13 ko:K01515 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000 Bacteria 2IIY0@201174,4D0P8@85004,COG0494@1,COG0494@2 NA|NA|NA L NUDIX domain LPKNPDNH_01283 702459.BBPR_0753 0.0 1523.1 Bifidobacteriales glgX 3.2.1.68 ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R09995,R11261 ko00000,ko00001,ko00002,ko01000 CBM48,GH13 Bacteria 2GJ00@201174,4CZGR@85004,COG1523@1,COG1523@2 NA|NA|NA G Belongs to the glycosyl hydrolase 13 family LPKNPDNH_01284 702459.BBPR_0754 7.4e-217 759.6 Bifidobacteriales ykiI Bacteria 2DSXT@1,2GKR7@201174,32UTZ@2,4CZBW@85004 NA|NA|NA LPKNPDNH_01286 398513.BBNG_00686 5.6e-43 179.9 Bifidobacteriales yafP 5.3.1.16 ko:K01814,ko:K03830,ko:K07146 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 Bacteria 2IQWZ@201174,4D16A@85004,COG0454@1,COG0454@2 NA|NA|NA K Acetyltransferase (GNAT) domain LPKNPDNH_01287 158787.BSCA_0892 4.8e-24 116.7 Bifidobacteriales yafP 5.3.1.16 ko:K01814,ko:K03830,ko:K07146 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 Bacteria 2IQWZ@201174,4D16A@85004,COG0454@1,COG0454@2 NA|NA|NA K Acetyltransferase (GNAT) domain LPKNPDNH_01288 158787.BSCA_0897 2e-16 91.3 Bifidobacteriales Bacteria 2HEN0@201174,4D0BA@85004,COG0477@1,COG2814@2 NA|NA|NA U Major Facilitator Superfamily LPKNPDNH_01289 398513.BBNG_00688 1.6e-73 282.0 Bifidobacteriales ko:K22296 ko00000,ko03000 Bacteria 2HVGM@201174,4D0XF@85004,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein LPKNPDNH_01290 398513.BBNG_00689 2.2e-72 278.1 Bifidobacteriales ko:K13640 ko00000,ko03000 Bacteria 2IFX0@201174,4D13W@85004,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance LPKNPDNH_01291 398513.BBNG_00690 2.6e-163 581.3 Bifidobacteriales 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 Bacteria 2GJQ7@201174,4CZ1F@85004,COG0656@1,COG0656@2 NA|NA|NA S Aldo/keto reductase family LPKNPDNH_01292 398513.BBNG_00691 1.2e-100 372.5 Bifidobacteriales 3.5.1.124 ko:K05520 ko00000,ko01000,ko01002 Bacteria 2GMMW@201174,4D0H3@85004,COG0693@1,COG0693@2 NA|NA|NA S DJ-1/PfpI family LPKNPDNH_01293 398513.BBNG_00692 9.7e-129 466.1 Bifidobacteriales Bacteria 2BE5B@1,2GP1A@201174,327W0@2,4CZYK@85004 NA|NA|NA LPKNPDNH_01295 702459.BBPR_0756 2.9e-108 397.9 Bifidobacteriales 3.4.13.21 ko:K05995 ko00000,ko01000,ko01002 Bacteria 2GN35@201174,4D10R@85004,COG3340@1,COG3340@2 NA|NA|NA E Peptidase family S51 LPKNPDNH_01296 702459.BBPR_0757 1.4e-275 954.9 Bifidobacteriales aroA GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJKX@201174,4CZBG@85004,COG0128@1,COG0128@2 NA|NA|NA E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate LPKNPDNH_01297 398513.BBNG_00697 9.8e-233 812.4 Bifidobacteriales ackA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.7.2.1,2.7.2.15 ko:K00925,ko:K19697 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1034,iIT341.HP0903m,iNJ661.Rv0409 Bacteria 2GJAW@201174,4CZ7V@85004,COG0282@1,COG0282@2 NA|NA|NA H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction LPKNPDNH_01298 398513.BBNG_00698 0.0 1087.4 Bifidobacteriales pta GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0006082,GO:0006083,GO:0006950,GO:0008150,GO:0008152,GO:0008959,GO:0009058,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016053,GO:0016407,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0030145,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0046914,GO:0050182,GO:0050896,GO:0055114,GO:0071704,GO:0072330,GO:1901576 1.1.1.40,2.3.1.19,2.3.1.8,3.6.3.21 ko:K00029,ko:K00625,ko:K00634,ko:K02028,ko:K04020,ko:K13788 ko00430,ko00620,ko00640,ko00650,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00650,map00680,map00710,map00720,map01100,map01120,map01200 M00169,M00172,M00236,M00357,M00579 R00216,R00230,R00921,R01174 RC00004,RC00105,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 iAF987.Gmet_1035,iAF987.Gmet_1637,iAF987.Gmet_2098,iE2348C_1286.E2348C_2692,iSB619.SA_RS03155,iYO844.BSU24090 Bacteria 2GJ5U@201174,4CZE6@85004,COG0280@1,COG0280@2 NA|NA|NA C phosphate acetyltransferase LPKNPDNH_01299 702459.BBPR_0760 6.8e-71 273.9 Bifidobacteriales XK27_07020 Bacteria 2GNQZ@201174,4CZZI@85004,COG4868@1,COG4868@2 NA|NA|NA S Domain of unknown function (DUF1846) LPKNPDNH_01300 888816.HMPREF9389_0434 4.2e-09 66.2 Streptococcus sanguinis Bacteria 1UABX@1239,1WS45@1305,4IKQ2@91061,COG4260@1,COG4260@2 NA|NA|NA S Domain of unknown function (DUF4339) LPKNPDNH_01301 398513.BBNG_00708 8.7e-303 1045.4 Bifidobacteriales guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 iJN746.PP_1032,iLJ478.TM1820,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833 Bacteria 2GM09@201174,4CZC3@85004,COG0518@1,COG0518@2,COG0519@1,COG0519@2 NA|NA|NA F Catalyzes the synthesis of GMP from XMP LPKNPDNH_01302 702459.BBPR_0768 0.0 1714.9 Bifidobacteriales xfp GO:0003674,GO:0003824,GO:0008150,GO:0009758 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 Bacteria 2GN27@201174,4CZT5@85004,COG3957@1,COG3957@2 NA|NA|NA G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase LPKNPDNH_01303 702459.BBPR_0769 3.4e-189 667.5 Bifidobacteriales pit ko:K03306 ko00000 2.A.20 Bacteria 2GJHK@201174,4CZM7@85004,COG0306@1,COG0306@2 NA|NA|NA P Phosphate transporter family LPKNPDNH_01304 398513.BBNG_00711 1.1e-115 422.5 Bifidobacteriales MA20_27875 ko:K02039,ko:K07220 ko00000 Bacteria 2HNQ5@201174,4CZVQ@85004,COG1392@1,COG1392@2 NA|NA|NA P Protein of unknown function DUF47 LPKNPDNH_01305 702459.BBPR_0771 3.1e-119 434.5 Bifidobacteriales Bacteria 2IBZ9@201174,4D07J@85004,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon LPKNPDNH_01306 702459.BBPR_0772 7.8e-233 812.8 Bifidobacteriales Bacteria 2I9G4@201174,4CZHY@85004,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase LPKNPDNH_01307 398513.BBNG_00714 9.9e-42 175.6 Bacteria pacL 3.6.3.8,3.6.3.9 ko:K01537,ko:K01539 ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978 ko00000,ko00001,ko01000,ko04147 3.A.3.1,3.A.3.2 Bacteria COG0474@1,COG0474@2 NA|NA|NA P ATPase, P-type transporting, HAD superfamily, subfamily IC LPKNPDNH_01308 702459.BBPR_0774 2.9e-179 634.4 Bifidobacteriales ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GIY8@201174,4CYUQ@85004,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities LPKNPDNH_01309 398513.BBNG_00716 1.8e-226 791.6 Bifidobacteriales ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IBJP@201174,4CZD5@85004,COG0842@1,COG0842@2 NA|NA|NA V ABC-2 family transporter protein LPKNPDNH_01310 702459.BBPR_0776 3.4e-253 880.6 Bifidobacteriales ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2H9HW@201174,4CZ1J@85004,COG0842@1,COG0842@2 NA|NA|NA V ABC-2 family transporter protein LPKNPDNH_01311 398513.BBNG_00718 2e-285 987.6 Bifidobacteriales 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GZ30@201174,4CYSX@85004,COG2865@1,COG2865@2 NA|NA|NA K Putative ATP-dependent DNA helicase recG C-terminal LPKNPDNH_01312 702459.BBPR_0778 4.3e-205 720.3 Bifidobacteriales Bacteria 2GMZX@201174,4D0DN@85004,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives IS30 family LPKNPDNH_01314 702459.BBPR_0779 1.2e-85 322.8 Bifidobacteriales Bacteria 2BPUM@1,2H7IF@201174,32IN6@2,4D2HU@85004 NA|NA|NA LPKNPDNH_01315 702459.BBPR_0780 1.2e-64 252.3 Bifidobacteriales Bacteria 2IT30@201174,4D1A7@85004,COG1196@1,COG1196@2 NA|NA|NA D MobA/MobL family LPKNPDNH_01316 398513.BBNG_00722 8.6e-48 196.1 Bifidobacteriales ko:K07483 ko00000 Bacteria 2IQ8F@201174,4D1BJ@85004,COG2963@1,COG2963@2 NA|NA|NA L Transposase LPKNPDNH_01317 398513.BBNG_00723 5.9e-182 643.3 Bifidobacteriales tnp7109-21 Bacteria 2GKDY@201174,4CZUB@85004,COG2801@1,COG2801@2 NA|NA|NA L Integrase core domain LPKNPDNH_01318 1123058.KB894256_gene1316 1.1e-26 125.6 Flavobacteriia 2.1.1.72 ko:K00571 ko00000,ko01000,ko02048 Bacteria 1HXKW@117743,2DB9A@1,2Z7VI@2,4NJ4U@976 NA|NA|NA S Adenine-specific methyltransferase EcoRI LPKNPDNH_01319 398513.BBNG_00727 9e-40 169.1 Bifidobacteriales Bacteria 2B5HY@1,2H0JI@201174,31YCN@2,4D1RA@85004 NA|NA|NA LPKNPDNH_01320 398513.BBNG_00728 3.6e-111 407.5 Bifidobacteriales pncA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.11.1,3.5.1.19 ko:K08281,ko:K12132 ko00760,ko01100,map00760,map01100 R01268 RC00100 ko00000,ko00001,ko01000,ko01001 iE2348C_1286.E2348C_1895,iECs_1301.ECs2475,iZ_1308.Z2802 Bacteria 2IFQW@201174,4CYTT@85004,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family LPKNPDNH_01322 398513.BBNG_00730 2e-106 391.7 Bifidobacteriales glmS 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 Bacteria 2GKH0@201174,4CZ1G@85004,COG0449@1,COG0449@2 NA|NA|NA M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source LPKNPDNH_01323 702459.BBPR_0788 4.3e-43 180.3 Bifidobacteriales glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 iNJ661.Rv3436c,iSB619.SA_RS11245,iYO844.BSU01780 Bacteria 2GKH0@201174,4CZ1G@85004,COG0449@1,COG0449@2 NA|NA|NA M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source LPKNPDNH_01325 702459.BBPR_0789 2e-239 834.7 Bifidobacteriales pbuX ko:K03458 ko00000 2.A.40 Bacteria 2GMH6@201174,4CZ9F@85004,COG2233@1,COG2233@2 NA|NA|NA F Permease family LPKNPDNH_01326 398513.BBNG_00732 1.3e-79 302.4 Bifidobacteriales xpt 2.4.2.22,2.4.2.7 ko:K00759,ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 R00190,R01229,R02142,R04378 RC00063,RC00122 ko00000,ko00001,ko01000,ko04147 Bacteria 2GJ3S@201174,4CYSZ@85004,COG0503@1,COG0503@2 NA|NA|NA F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis LPKNPDNH_01327 398513.BBNG_00733 0.0 1112.4 Bifidobacteriales yrhL Bacteria 2GKI5@201174,4D0BY@85004,COG1835@1,COG1835@2 NA|NA|NA I Psort location CytoplasmicMembrane, score 9.99 LPKNPDNH_01328 702459.BBPR_0792 0.0 1578.5 Bifidobacteriales pcrA GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 2GISS@201174,4CYRJ@85004,COG0210@1,COG0210@2 NA|NA|NA L DNA helicase LPKNPDNH_01329 702459.BBPR_0793 8.2e-64 249.6 Bifidobacteriales Bacteria 2CBVU@1,2IKKE@201174,3324G@2,4D106@85004 NA|NA|NA S Domain of unknown function (DUF4418) LPKNPDNH_01330 702459.BBPR_0794 9.4e-212 742.7 Bifidobacteriales ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2H8C2@201174,4CZB5@85004,COG0577@1,COG0577@2 NA|NA|NA V FtsX-like permease family LPKNPDNH_01331 398513.BBNG_00737 1.9e-128 465.3 Bifidobacteriales lolD ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2IATV@201174,4CZMH@85004,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter LPKNPDNH_01332 398513.BBNG_00738 1e-108 399.4 Bifidobacteriales rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 ko:K02986 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GIRX@201174,4CYSP@85004,COG0522@1,COG0522@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit LPKNPDNH_01333 702459.BBPR_0797 0.0 1312.7 Bifidobacteriales oatA GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016020,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 Bacteria 2GKI5@201174,4D0BY@85004,COG1835@1,COG1835@2 NA|NA|NA I Psort location CytoplasmicMembrane, score 9.99 LPKNPDNH_01334 398513.BBNG_00740 6.5e-136 490.0 Bifidobacteriales pgm3 Bacteria 2GK2I@201174,4CZH2@85004,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family LPKNPDNH_01335 398513.BBNG_00741 3.8e-64 250.8 Bifidobacteriales WQ51_05790 Bacteria 2II1J@201174,4D0VH@85004,COG4768@1,COG4768@2 NA|NA|NA S Bacterial protein of unknown function (DUF948) LPKNPDNH_01336 398513.BBNG_00742 1.1e-36 158.7 Bifidobacteriales Bacteria 2B9VR@1,2IQYT@201174,3238X@2,4D16I@85004 NA|NA|NA LPKNPDNH_01337 398513.BBNG_00743 0.0 1725.7 Bifidobacteriales alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GIUG@201174,4CZQN@85004,COG0013@1,COG0013@2 NA|NA|NA J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain LPKNPDNH_01338 398513.BBNG_00744 3e-75 287.7 Bifidobacteriales yqgF GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K07447 ko00000,ko01000 Bacteria 2IQB0@201174,4D0WQ@85004,COG0816@1,COG0816@2 NA|NA|NA L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA LPKNPDNH_01339 702459.BBPR_0803 7.1e-188 663.3 Bifidobacteriales mltG ko:K07082 ko00000 Bacteria 2GKGQ@201174,4CZID@85004,COG1559@1,COG1559@2 NA|NA|NA S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation LPKNPDNH_01340 398513.BBNG_00746 6.3e-47 193.7 Bifidobacteriales 3.4.23.43 ko:K02654 M00331 ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 Bacteria 2B59B@1,2GRM1@201174,31Y3G@2,4D110@85004 NA|NA|NA S Type IV leader peptidase family LPKNPDNH_01341 702459.BBPR_0805 1.6e-219 768.5 Bifidobacteriales aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0976,iNJ661.Rv2540c Bacteria 2GJJN@201174,4CZ43@85004,COG0082@1,COG0082@2 NA|NA|NA E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system LPKNPDNH_01342 702459.BBPR_0806 0.0 1086.6 Bifidobacteriales aroK GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003856,GO:0004765,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016835,GO:0016838,GO:0017076,GO:0019438,GO:0019632,GO:0019752,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71,4.2.3.4 ko:K00891,ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIUZ@201174,4CZ2G@85004,COG0337@1,COG0337@2,COG0703@1,COG0703@2 NA|NA|NA H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) LPKNPDNH_01343 702459.BBPR_0807 5.9e-79 300.1 Bifidobacteriales aroQ GO:0003674,GO:0003824,GO:0003855,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 iIT341.HP1038 Bacteria 2IMBY@201174,4D0Q6@85004,COG0757@1,COG0757@2 NA|NA|NA E Catalyzes a trans-dehydration via an enolate intermediate LPKNPDNH_01344 702459.BBPR_0808 1.9e-75 289.3 Actinobacteria Bacteria 2EGCD@1,2GZHT@201174,33A46@2 NA|NA|NA LPKNPDNH_01345 702459.BBPR_0809 1.7e-120 438.7 Bifidobacteriales Bacteria 2IQKB@201174,4D2UE@85004,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon LPKNPDNH_01346 398513.BBNG_01395 2.6e-07 62.8 Bifidobacteriales 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria 2GNWT@201174,4CZMM@85004,COG3764@1,COG3764@2 NA|NA|NA M Sortase family LPKNPDNH_01347 398513.BBNG_00754 0.0 1128.2 Bifidobacteriales pyrG GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1276,iECO103_1326.ECO103_3323,iHN637.CLJU_RS01075,iNJ661.Rv1699,iPC815.YPO3377 Bacteria 2GJ13@201174,4CYWE@85004,COG0504@1,COG0504@2 NA|NA|NA F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates LPKNPDNH_01348 398513.BBNG_00755 3.6e-290 1003.4 Bifidobacteriales sufB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 ko:K07033,ko:K09014 ko00000 Bacteria 2GKCZ@201174,4CZPQ@85004,COG0719@1,COG0719@2 NA|NA|NA O FeS assembly protein SufB LPKNPDNH_01349 398513.BBNG_00756 1.4e-234 818.5 Bifidobacteriales sufD GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0040007,GO:0043207,GO:0044085,GO:0044237,GO:0044403,GO:0044419,GO:0050896,GO:0051186,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071840,GO:0075136 ko:K09015 ko00000 iB21_1397.B21_01640,iECBD_1354.ECBD_1964,iECB_1328.ECB_01650,iECD_1391.ECD_01650,iUMNK88_1353.UMNK88_2144 Bacteria 2GJNV@201174,4CZEE@85004,COG0719@1,COG0719@2 NA|NA|NA O FeS assembly protein SufD LPKNPDNH_01350 398513.BBNG_00757 2.4e-144 518.1 Bifidobacteriales sufC ko:K09013 ko00000,ko02000 Bacteria 2GKB7@201174,4CZU1@85004,COG0396@1,COG0396@2 NA|NA|NA O FeS assembly ATPase SufC LPKNPDNH_01351 398513.BBNG_00758 1.6e-241 841.6 Bifidobacteriales sufS GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 Bacteria 2GIVK@201174,4CZIU@85004,COG0520@1,COG0520@2 NA|NA|NA E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine LPKNPDNH_01352 398513.BBNG_00759 2.6e-100 371.3 Bifidobacteriales iscU ko:K04488 ko00000 Bacteria 2IHY9@201174,4CZU5@85004,COG0822@1,COG0822@2 NA|NA|NA C SUF system FeS assembly protein, NifU family LPKNPDNH_01353 398513.BBNG_00760 1.2e-108 399.1 Bifidobacteriales yitW ko:K02612 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 2IKUH@201174,4CYRH@85004,COG2151@1,COG2151@2 NA|NA|NA S Iron-sulfur cluster assembly protein LPKNPDNH_01354 398513.BBNG_00761 4.7e-243 846.7 Bifidobacteriales glgC GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2768 Bacteria 2I2EF@201174,4CZ4E@85004,COG0448@1,COG0448@2 NA|NA|NA H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans LPKNPDNH_01355 398513.BBNG_00762 4e-164 583.9 Bifidobacteriales spoU 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 2GJ12@201174,4CYQ6@85004,COG0566@1,COG0566@2 NA|NA|NA J SpoU rRNA Methylase family LPKNPDNH_01357 398513.BBNG_00763 4.7e-83 313.9 Bifidobacteriales rsmE 2.1.1.193 ko:K09761 ko00000,ko01000,ko03009 Bacteria 2GTKX@201174,4CZAD@85004,COG1385@1,COG1385@2 NA|NA|NA J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit LPKNPDNH_01358 398513.BBNG_00763 4.9e-35 153.3 Bifidobacteriales rsmE 2.1.1.193 ko:K09761 ko00000,ko01000,ko03009 Bacteria 2GTKX@201174,4CZAD@85004,COG1385@1,COG1385@2 NA|NA|NA J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit LPKNPDNH_01359 398513.BBNG_00764 4.4e-58 230.3 Bifidobacteriales hinT GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019478,GO:0019752,GO:0043436,GO:0043530,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046144,GO:0046395,GO:0046416,GO:0046436,GO:0055130,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.1.226,2.1.1.227 ko:K02503,ko:K06442 ko00000,ko01000,ko03009,ko04147 Bacteria 2IHPT@201174,4D130@85004,COG0537@1,COG0537@2 NA|NA|NA FG Scavenger mRNA decapping enzyme C-term binding LPKNPDNH_01360 398513.BBNG_00765 3.4e-197 694.1 Bifidobacteriales phoH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06217 ko00000 Bacteria 2GK0W@201174,4CZJH@85004,COG1702@1,COG1702@2 NA|NA|NA T PhoH-like protein LPKNPDNH_01361 398513.BBNG_00766 7.4e-100 369.8 Bifidobacteriales ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 ko:K01489,ko:K03474,ko:K03595,ko:K07042 ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100 M00124 R01878,R02485,R05838,R08221 RC00074,RC00514,RC01476 ko00000,ko00001,ko00002,ko01000,ko03009,ko03029 Bacteria 2GMUF@201174,4CZJF@85004,COG0319@1,COG0319@2 NA|NA|NA S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA LPKNPDNH_01362 702459.BBPR_0824 2.4e-251 874.4 Bifidobacteriales corC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2GIWR@201174,4CZ1W@85004,COG1253@1,COG1253@2 NA|NA|NA S CBS domain LPKNPDNH_01363 398513.BBNG_00768 1.5e-186 658.7 Bifidobacteriales era GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043021,GO:0043024,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070181,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:1901363 ko:K03595 ko00000,ko03009,ko03029 Bacteria 2GJJE@201174,4CYZH@85004,COG1159@1,COG1159@2 NA|NA|NA S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism LPKNPDNH_01364 398513.BBNG_00769 0.0 1341.6 Bifidobacteriales fadD 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 2GIXQ@201174,4CYYJ@85004,COG1022@1,COG1022@2 NA|NA|NA I AMP-binding enzyme LPKNPDNH_01365 702459.BBPR_0827 1.1e-201 709.1 Bifidobacteriales pntA 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 Bacteria 2I2FZ@201174,4CZZ3@85004,COG3288@1,COG3288@2 NA|NA|NA C NAD(P) transhydrogenase subunit alpha part 1 K00324 LPKNPDNH_01366 702459.BBPR_0828 4.4e-44 183.7 Bifidobacteriales pntA 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 Bacteria 2IKR9@201174,4D12D@85004,COG3288@1,COG3288@2 NA|NA|NA C 4TM region of pyridine nucleotide transhydrogenase, mitoch LPKNPDNH_01367 398513.BBNG_00772 2.3e-233 814.7 Bifidobacteriales pntB 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 R00112 RC00001 ko00000,ko00001,ko01000 Bacteria 2GNKB@201174,4CZF5@85004,COG1282@1,COG1282@2 NA|NA|NA C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane LPKNPDNH_01368 398513.BBNG_00773 1.8e-189 668.3 Bifidobacteriales ko:K06889 ko00000 Bacteria 2HZEB@201174,4D02D@85004,COG1073@1,COG1073@2 NA|NA|NA S alpha beta LPKNPDNH_01369 398513.BBNG_00774 8.3e-95 353.2 Bifidobacteriales ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02897 ko03010,map03010 M00178 ko00000,ko00001,ko00002,ko03011 Bacteria 2GJPJ@201174,4CZ7W@85004,COG1825@1,COG1825@2 NA|NA|NA J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance LPKNPDNH_01370 398513.BBNG_00775 2.4e-225 787.7 Bifidobacteriales ilvE GO:0000082,GO:0000278,GO:0003674,GO:0003824,GO:0004084,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006573,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008283,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009082,GO:0009083,GO:0009098,GO:0009099,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0022402,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044770,GO:0044772,GO:0044843,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607,GO:1903047 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GKJ1@201174,4CZD9@85004,COG0115@1,COG0115@2 NA|NA|NA E Amino-transferase class IV LPKNPDNH_01371 702459.BBPR_0833 1.8e-46 191.4 Bifidobacteriales Bacteria 2IRS9@201174,4D018@85004,COG4186@1,COG4186@2 NA|NA|NA S phosphoesterase or phosphohydrolase LPKNPDNH_01372 398513.BBNG_00776 2.7e-99 367.9 Bifidobacteriales 3.1.4.37 ko:K01121 ko00000,ko01000,ko04147 Bacteria 2HZFC@201174,4D08U@85004,COG5324@1,COG5324@2 NA|NA|NA T RNA ligase LPKNPDNH_01373 398513.BBNG_00777 1.2e-135 489.2 Bifidobacteriales GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 2GMI4@201174,4CZ51@85004,COG2860@1,COG2860@2 NA|NA|NA S UPF0126 domain LPKNPDNH_01374 398513.BBNG_00778 9.9e-34 149.1 Bifidobacteriales rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02968 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ73@201174,4D18U@85004,COG0268@1,COG0268@2 NA|NA|NA J Binds directly to 16S ribosomal RNA LPKNPDNH_01375 398513.BBNG_00779 0.0 1243.0 Bifidobacteriales lepA GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K03596 ko05134,map05134 ko00000,ko00001 Bacteria 2GJAB@201174,4CYWI@85004,COG0481@1,COG0481@2 NA|NA|NA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner LPKNPDNH_01376 398513.BBNG_00780 1.5e-245 855.1 Bifidobacteriales hemN GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 iNJ661.Rv2388c Bacteria 2GJXX@201174,4CZ81@85004,COG0635@1,COG0635@2 NA|NA|NA H Involved in the biosynthesis of porphyrin-containing compound LPKNPDNH_01377 1437608.BBIA_1369 3.4e-12 76.6 Bifidobacteriales ko:K07149 ko00000 Bacteria 2IADD@201174,4D0K2@85004,COG2364@1,COG2364@2 NA|NA|NA S Membrane LPKNPDNH_01378 702459.BBPR_0840 1.4e-287 995.0 Bifidobacteriales alaA GO:0003674,GO:0003824,GO:0004021,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0019842,GO:0030170,GO:0030632,GO:0032787,GO:0033554,GO:0036094,GO:0040007,GO:0042221,GO:0042851,GO:0042852,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0046677,GO:0047635,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.2,2.6.1.66 ko:K00814,ko:K14260 ko00220,ko00250,ko00290,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00220,map00250,map00290,map00710,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00171 R00258,R01215 RC00006,RC00008,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 iNJ661.Rv0337c Bacteria 2GJ7R@201174,4CZVJ@85004,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase, class I II LPKNPDNH_01379 702459.BBPR_0841 0.0 1414.4 Bifidobacteriales tetP ko:K02355 ko00000,ko03012,ko03029 Bacteria 2GJ64@201174,4CZM5@85004,COG0480@1,COG0480@2 NA|NA|NA J Elongation factor G, domain IV LPKNPDNH_01380 702459.BBPR_0842 0.0 3057.3 Bifidobacteriales gltB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 Bacteria 2GN09@201174,4CZB8@85004,COG0067@1,COG0067@2,COG0069@1,COG0069@2,COG0070@1,COG0070@2 NA|NA|NA E glutamate synthase NADPH large subunit LPKNPDNH_01381 398513.BBNG_00785 2.7e-304 1050.4 Bifidobacteriales gltD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 iJN678.gltD,iNJ661.Rv3858c,iSB619.SA_RS02450 Bacteria 2GJ0A@201174,4CZ7B@85004,COG0493@1,COG0493@2 NA|NA|NA C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster LPKNPDNH_01382 398513.BBNG_00786 3.6e-82 310.8 Bifidobacteriales Bacteria 2BI32@1,2IDD6@201174,32C84@2,4D0PC@85004 NA|NA|NA LPKNPDNH_01383 702459.BBPR_0846 1.1e-244 852.0 Bifidobacteriales glgA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 ko:K16148 ko00500,ko01100,map00500,map01100 R02421,R11530 RC00005,RC00049,RC02748 ko00000,ko00001,ko01000,ko01003 GT4 Bacteria 2I2EE@201174,4CZKY@85004,COG0297@1,COG0297@2 NA|NA|NA G Starch synthase catalytic domain LPKNPDNH_01384 702459.BBPR_0847 1.6e-182 645.2 Bifidobacteriales modF GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.21,3.6.3.34 ko:K02013,ko:K02028,ko:K05776 ko02010,map02010 M00189,M00236,M00240 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14,3.A.1.3 Bacteria 2GIXX@201174,4CZDS@85004,COG1119@1,COG1119@2 NA|NA|NA P ATPases associated with a variety of cellular activities LPKNPDNH_01385 702459.BBPR_0848 1.5e-158 565.5 Bifidobacteriales ybeM ko:K11206 ko00000,ko01000 Bacteria 2GMQA@201174,4D07K@85004,COG0388@1,COG0388@2 NA|NA|NA S Carbon-nitrogen hydrolase LPKNPDNH_01386 398513.BBNG_00790 1.3e-113 415.6 Bifidobacteriales ko:K07126 ko00000 Bacteria 2GTVX@201174,4D1KI@85004,COG0790@1,COG0790@2 NA|NA|NA S Sel1-like repeats. LPKNPDNH_01387 702459.BBPR_0850 1.2e-185 655.6 Bifidobacteriales cbh 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 Bacteria 2GK9Z@201174,4CZNU@85004,COG3049@1,COG3049@2 NA|NA|NA M Linear amide C-N hydrolase, choloylglycine hydrolase family protein LPKNPDNH_01388 702459.BBPR_0851 1.7e-61 242.7 Bifidobacteriales Bacteria 2HUEV@201174,4CZKS@85004,COG4260@1,COG4260@2 NA|NA|NA S Short C-terminal domain LPKNPDNH_01389 702459.BBPR_0852 9.3e-181 639.4 Bifidobacteriales GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 ko:K07485 ko00000 Bacteria 2GJK7@201174,4D0ME@85004,COG3464@1,COG3464@2 NA|NA|NA L Transposase LPKNPDNH_01390 702459.BBPR_0853 1.6e-28 131.3 Bacteria ko:K07485 ko00000 Bacteria COG3464@1,COG3464@2 NA|NA|NA LPKNPDNH_01391 566552.BIFCAT_00588 2.3e-31 141.0 Bifidobacteriales XK26_04895 Bacteria 28P3D@1,2GP4T@201174,2ZBZ3@2,4D0S7@85004 NA|NA|NA LPKNPDNH_01392 702459.BBPR_0854 5.1e-22 110.2 Bifidobacteriales XK26_04895 Bacteria 28P3D@1,2GP4T@201174,2ZBZ3@2,4D0S7@85004 NA|NA|NA LPKNPDNH_01393 566552.BIFCAT_00589 0.0 2116.3 Bifidobacteriales Bacteria 2HJPR@201174,4CZD6@85004,COG1061@1,COG1061@2 NA|NA|NA KL Type III restriction enzyme res subunit LPKNPDNH_01394 566552.BIFCAT_00590 1.9e-38 164.9 Bifidobacteriales Bacteria 2I5BK@201174,4D2YR@85004,COG0827@1,COG0827@2 NA|NA|NA L Eco57I restriction-modification methylase LPKNPDNH_01395 566552.BIFCAT_00590 1.8e-55 221.9 Bifidobacteriales Bacteria 2I5BK@201174,4D2YR@85004,COG0827@1,COG0827@2 NA|NA|NA L Eco57I restriction-modification methylase LPKNPDNH_01396 566552.BIFCAT_00591 2.8e-182 644.4 Bifidobacteriales 3.1.21.4 ko:K01155 ko00000,ko01000,ko02048 Bacteria 2IHER@201174,4D0PM@85004,COG1002@1,COG1002@2 NA|NA|NA V Type III restriction enzyme res subunit LPKNPDNH_01397 563038.HMPREF0851_01592 2.5e-56 226.1 Bacilli Bacteria 1VCWV@1239,2C171@1,2Z7ZR@2,4HNFG@91061 NA|NA|NA S SIR2-like domain LPKNPDNH_01398 78345.BMERY_1183 1.2e-88 332.8 Bifidobacteriales ko:K06915 ko00000 Bacteria 2INIE@201174,4D1JH@85004,COG0433@1,COG0433@2 NA|NA|NA S AAA-like domain LPKNPDNH_01399 78345.BMERY_1183 1.1e-128 466.5 Bifidobacteriales ko:K06915 ko00000 Bacteria 2INIE@201174,4D1JH@85004,COG0433@1,COG0433@2 NA|NA|NA S AAA-like domain LPKNPDNH_01400 216816.GS08_04880 0.0 1649.4 Bifidobacteriales Bacteria 2I99F@201174,4CZ4G@85004,COG1479@1,COG1479@2 NA|NA|NA S Protein of unknown function DUF262 LPKNPDNH_01401 78345.BMERY_0240 1.1e-29 135.2 Bifidobacteriales Bacteria 2E37J@1,2GR14@201174,32Y79@2,4D1IM@85004 NA|NA|NA LPKNPDNH_01402 398513.BBNG_00803 4e-71 274.2 Bifidobacteriales rarD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944 3.4.17.13 ko:K01297,ko:K05786 ko00000,ko01000,ko01002,ko01011,ko02000 2.A.7.7 Bacteria 2HZT1@201174,4D1NI@85004,COG0346@1,COG0346@2,COG2962@1,COG2962@2,COG4279@1,COG4279@2 NA|NA|NA E Rard protein LPKNPDNH_01403 158787.BSCA_1450 1.4e-23 115.2 Bifidobacteriales rarD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944 ko:K05786 ko00000,ko02000 2.A.7.7 Bacteria 2GKCP@201174,4D0PS@85004,COG2962@1,COG2962@2 NA|NA|NA S EamA-like transporter family LPKNPDNH_01404 398513.BBNG_00804 3e-178 630.9 Bifidobacteriales Bacteria 2GNKU@201174,4CZVA@85004,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold LPKNPDNH_01405 702459.BBPR_0869 7e-206 723.0 Bifidobacteriales trmI GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 ko:K07442 ko00000,ko01000,ko03016 Bacteria 2GJPD@201174,4CYUG@85004,COG2519@1,COG2519@2 NA|NA|NA J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA LPKNPDNH_01406 702459.BBPR_0870 2e-100 371.7 Bifidobacteriales sixA 3.6.1.55 ko:K03574,ko:K08296 ko00000,ko01000,ko03400 Bacteria 2GJ0I@201174,4D05N@85004,COG2062@1,COG2062@2 NA|NA|NA T Phosphoglycerate mutase family LPKNPDNH_01407 398513.BBNG_00807 3.9e-242 843.6 Bifidobacteriales int ko:K14059 ko00000 Bacteria 2GMMI@201174,4D0E4@85004,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase, N-terminal SAM-like domain LPKNPDNH_01408 1341695.BBOMB_1075 5.1e-45 187.6 Bifidobacteriales Bacteria 2IN7F@201174,4D2UP@85004,COG2856@1,COG2856@2 NA|NA|NA E IrrE N-terminal-like domain LPKNPDNH_01409 1193128.A200_00080 6e-16 90.9 Bifidobacteriales Bacteria 295ZC@1,2GUHR@201174,2ZTA4@2,4D1I4@85004 NA|NA|NA LPKNPDNH_01410 702459.BBPR_0878 3.8e-50 204.5 Bifidobacteriales Bacteria 2C5TS@1,2IT81@201174,2ZX0Y@2,4D1BF@85004 NA|NA|NA LPKNPDNH_01411 762211.BSTEL_1987 2.5e-104 385.6 Bifidobacteriales Bacteria 2IA5J@201174,4D0WF@85004,COG3943@1,COG3943@2 NA|NA|NA S Virulence protein RhuM family LPKNPDNH_01412 702459.BBPR_0880 1.2e-54 219.2 Bifidobacteriales Bacteria 2BNW4@1,2H5A1@201174,32HJZ@2,4D27T@85004 NA|NA|NA LPKNPDNH_01413 702459.BBPR_0881 1.9e-34 151.4 Bifidobacteriales Bacteria 2B957@1,2H6V7@201174,322G7@2,4D2AU@85004 NA|NA|NA LPKNPDNH_01414 78345.BMERY_0905 8.2e-53 213.4 Bifidobacteriales Bacteria 2B9A9@1,2H71J@201174,322MP@2,4D2BF@85004 NA|NA|NA LPKNPDNH_01415 1437608.BBIA_2185 3.3e-22 111.7 Bifidobacteriales Bacteria 2B9A9@1,2H71J@201174,322MP@2,4D2BF@85004 NA|NA|NA LPKNPDNH_01416 702459.BBPR_0883 2e-122 445.3 Bifidobacteriales ko:K07741 ko00000 Bacteria 2IMZ0@201174,4D0PU@85004,COG3617@1,COG3617@2,COG3645@1,COG3645@2 NA|NA|NA K BRO family, N-terminal domain LPKNPDNH_01419 398513.BBNG_00822 2.2e-37 161.0 Bifidobacteriales Bacteria 2BIIE@1,2GSTG@201174,32CR4@2,4D1F3@85004 NA|NA|NA LPKNPDNH_01421 398513.BBNG_00824 5.6e-36 156.4 Bifidobacteriales Bacteria 2AE10@1,2HDGN@201174,313TP@2,4D2QP@85004 NA|NA|NA LPKNPDNH_01423 702459.BBPR_0890 8.6e-93 346.3 Bifidobacteriales ssb1 ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 2GMM3@201174,4D25T@85004,COG0629@1,COG0629@2 NA|NA|NA L Single-strand binding protein family LPKNPDNH_01424 702459.BBPR_0891 1.4e-275 954.9 Bifidobacteriales ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 2I9G6@201174,4D06E@85004,COG1475@1,COG1475@2 NA|NA|NA K ParB-like nuclease domain LPKNPDNH_01425 398513.BBNG_00828 1.9e-145 521.9 Bifidobacteriales ko:K19505,ko:K21885 ko00000,ko03000 Bacteria 2II2A@201174,4D0WC@85004,COG0640@1,COG0640@2 NA|NA|NA K Transcriptional regulator LPKNPDNH_01426 398513.BBNG_00829 1.5e-26 124.8 Bifidobacteriales Bacteria 2BA8N@1,2H8CW@201174,323NR@2,4D2E3@85004 NA|NA|NA LPKNPDNH_01427 398513.BBNG_00830 2.6e-81 307.8 Bifidobacteriales Bacteria 2GQKB@201174,4D1JQ@85004,COG1403@1,COG1403@2 NA|NA|NA V HNH endonuclease LPKNPDNH_01428 702459.BBPR_0895 1.9e-109 401.7 Bifidobacteriales ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 2IM4T@201174,4D15Z@85004,COG1949@1,COG1949@2 NA|NA|NA A 3'-to-5' exoribonuclease specific for small oligoribonucleotides LPKNPDNH_01430 398513.BBNG_00833 3e-50 204.1 Bifidobacteriales Bacteria 2B46U@1,2GY2T@201174,31WXX@2,4D1ND@85004 NA|NA|NA LPKNPDNH_01432 702459.BBPR_0899 9.7e-143 512.7 Bifidobacteriales Bacteria 2AZUG@1,2GQ7F@201174,31S3T@2,4D1BR@85004 NA|NA|NA LPKNPDNH_01433 398513.BBNG_00836 1.3e-34 151.8 Bifidobacteriales ko:K07339 ko00000,ko01000,ko02048 Bacteria 2GVZW@201174,4D1FJ@85004,COG1724@1,COG1724@2 NA|NA|NA N HicA toxin of bacterial toxin-antitoxin, LPKNPDNH_01434 398513.BBNG_00837 1.5e-73 282.0 Bifidobacteriales ko:K18843 ko00000,ko02048 Bacteria 2IPZP@201174,4D0YY@85004,COG1598@1,COG1598@2 NA|NA|NA S HicB_like antitoxin of bacterial toxin-antitoxin system LPKNPDNH_01436 398513.BBNG_00839 3.2e-32 143.7 Bifidobacteriales Bacteria 2GQY8@201174,4D1IJ@85004,COG3311@1,COG3311@2 NA|NA|NA K Transcriptional regulator LPKNPDNH_01439 398513.BBNG_00842 8.1e-66 256.1 Bifidobacteriales ko:K07451 ko00000,ko01000,ko02048 Bacteria 299WA@1,2GS5R@201174,2ZWY7@2,4D2E2@85004 NA|NA|NA LPKNPDNH_01440 702459.BBPR_0907 6.7e-115 419.9 Bifidobacteriales Bacteria 2IICA@201174,4D25R@85004,COG4983@1,COG4983@2 NA|NA|NA S Bifunctional DNA primase/polymerase, N-terminal LPKNPDNH_01441 398513.BBNG_00844 4.8e-69 266.9 Bifidobacteriales Bacteria 2B17E@1,2HZY7@201174,31TMT@2,4D27V@85004 NA|NA|NA LPKNPDNH_01442 702459.BBPR_0909 0.0 1270.4 Bifidobacteriales Bacteria 2GNSB@201174,4D0MR@85004,COG4626@1,COG4626@2 NA|NA|NA S Terminase LPKNPDNH_01443 398513.BBNG_00846 5.5e-280 969.5 Bifidobacteriales Bacteria 2DBV2@1,2HZXG@201174,2ZB9E@2,4D251@85004 NA|NA|NA S Phage portal protein, SPP1 Gp6-like LPKNPDNH_01444 702459.BBPR_0911 7.4e-241 839.3 Actinobacteria Bacteria 2DQ4S@1,2GQI7@201174,334RC@2 NA|NA|NA LPKNPDNH_01445 398513.BBNG_00848 1.1e-43 182.2 Bifidobacteriales Bacteria 2B3F7@1,2GWMR@201174,31W44@2,4D1R2@85004 NA|NA|NA LPKNPDNH_01447 702459.BBPR_0913 3.7e-78 297.7 Bifidobacteriales Bacteria 2B0XW@1,2HZTW@201174,31TAU@2,4D1QW@85004 NA|NA|NA LPKNPDNH_01448 398513.BBNG_00849 2.4e-157 561.6 Bifidobacteriales Bacteria 2I9E6@201174,4D045@85004,COG4653@1,COG4653@2 NA|NA|NA S Phage capsid family LPKNPDNH_01449 398513.BBNG_00850 8.1e-65 253.1 Bifidobacteriales Bacteria 2B5FX@1,2GWPK@201174,31YAK@2,4D1P2@85004 NA|NA|NA LPKNPDNH_01450 702459.BBPR_0916 2.2e-90 338.2 Bifidobacteriales Bacteria 290X4@1,2GZNG@201174,2ZNIX@2,4D298@85004 NA|NA|NA LPKNPDNH_01451 398513.BBNG_00852 1.3e-78 298.9 Bifidobacteriales Bacteria 2DY8F@1,2GRSW@201174,348MB@2,4D1II@85004 NA|NA|NA LPKNPDNH_01452 398513.BBNG_00853 6.1e-73 280.0 Bifidobacteriales Bacteria 2EPKQ@1,2ISZ5@201174,33H7B@2,4D1CJ@85004 NA|NA|NA LPKNPDNH_01453 398513.BBNG_00854 4.9e-72 276.9 Bifidobacteriales Bacteria 2B64Z@1,2H1JX@201174,31Z1W@2,4D1RV@85004 NA|NA|NA LPKNPDNH_01454 702459.BBPR_0920 3.6e-94 350.9 Bifidobacteriales Bacteria 2EMRF@1,2GR0S@201174,33FDY@2,4D1HP@85004 NA|NA|NA LPKNPDNH_01455 398513.BBNG_00856 7.7e-83 313.2 Bifidobacteriales Bacteria 2BDK2@1,2HCXD@201174,3279G@2,4D2PB@85004 NA|NA|NA LPKNPDNH_01456 398513.BBNG_00857 6.3e-53 213.0 Bifidobacteriales Bacteria 2BMIJ@1,2H1C7@201174,32G3G@2,4D1RU@85004 NA|NA|NA LPKNPDNH_01457 702459.BBPR_0923 0.0 1743.4 Bifidobacteriales Bacteria 2I92I@201174,4D030@85004,COG5283@1,COG5283@2 NA|NA|NA S Phage-related minor tail protein LPKNPDNH_01458 398513.BBNG_00859 1.8e-147 528.5 Bifidobacteriales Bacteria 2GSFE@201174,4D1EK@85004,COG4722@1,COG4722@2 NA|NA|NA S phage tail LPKNPDNH_01459 398513.BBNG_00860 0.0 1265.0 Bifidobacteriales Bacteria 2GKYX@201174,4D0B9@85004,COG4926@1,COG4926@2 NA|NA|NA S Prophage endopeptidase tail LPKNPDNH_01460 398513.BBNG_00861 2.8e-64 251.1 Actinobacteria Bacteria 2A739@1,2HAAN@201174,30VYV@2 NA|NA|NA LPKNPDNH_01461 398513.BBNG_00862 4e-214 751.1 Bifidobacteriales Bacteria 2AR26@1,2IF4V@201174,31GB5@2,4D0GW@85004 NA|NA|NA LPKNPDNH_01462 78345.BMERY_0864 6.2e-50 204.5 Bifidobacteriales Bacteria 2GXAB@201174,4D1NP@85004,COG3468@1,COG3468@2 NA|NA|NA MU outer membrane autotransporter barrel domain protein LPKNPDNH_01463 702459.BBPR_0929 3.6e-39 167.9 Bifidobacteriales Bacteria 2BJPU@1,2GZ2E@201174,32E1F@2,4D1PK@85004 NA|NA|NA LPKNPDNH_01464 398513.BBNG_00865 6.5e-67 260.0 Bifidobacteriales Bacteria 2DRCI@1,2GPSH@201174,33B7V@2,4D1E1@85004 NA|NA|NA S SPP1 phage holin LPKNPDNH_01465 702459.BBPR_0931 2.2e-127 461.8 Actinobacteria 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Bacteria 2IK6V@201174,COG0791@1,COG0791@2,COG3409@1,COG3409@2 NA|NA|NA M NLP P60 protein LPKNPDNH_01469 702459.BBPR_0933 0.0 1536.5 Bifidobacteriales metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0030312,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0040007,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0071944,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131 Bacteria 2GIXA@201174,4CYWM@85004,COG0620@1,COG0620@2 NA|NA|NA E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation LPKNPDNH_01470 398513.BBNG_00869 9e-161 572.8 Bifidobacteriales metF GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 ko:K00297,ko:K21010 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,ko02025,map00670,map00720,map01100,map01120,map01200,map01523,map02025 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 iPC815.YPO0117,iSBO_1134.SBO_3961 Bacteria 2GJTN@201174,4CZ22@85004,COG0685@1,COG0685@2 NA|NA|NA E Methylenetetrahydrofolate reductase LPKNPDNH_01472 702459.BBPR_0936 0.0 2043.5 Bifidobacteriales glnE GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 ko:K00982 ko00000,ko01000 Bacteria 2GJ91@201174,4CYQE@85004,COG1391@1,COG1391@2 NA|NA|NA H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell LPKNPDNH_01473 702459.BBPR_0937 1.4e-181 642.1 Bifidobacteriales pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 iZ_1308.Z5856 Bacteria 2GKNA@201174,4CYZR@85004,COG0540@1,COG0540@2 NA|NA|NA F Belongs to the ATCase OTCase family LPKNPDNH_01474 702459.BBPR_0938 2e-73 281.6 Bifidobacteriales pyrI GO:0003674,GO:0003824,GO:0004070,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00608,ko:K00610 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 Bacteria 2IFDF@201174,4D0QN@85004,COG1781@1,COG1781@2 NA|NA|NA F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein LPKNPDNH_01475 702459.BBPR_0939 4.7e-279 966.5 Bifidobacteriales pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ0T@201174,4CZIW@85004,COG0044@1,COG0044@2 NA|NA|NA F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily LPKNPDNH_01476 398513.BBNG_00875 2.6e-180 637.9 Bifidobacteriales pyrF GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 ko:K01591,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00051 R00965,R01870,R08231 RC00063,RC00409,RC00611 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS17585 Bacteria 2GKWK@201174,4CZAK@85004,COG0284@1,COG0284@2 NA|NA|NA F Belongs to the OMP decarboxylase family. Type 2 subfamily LPKNPDNH_01477 398513.BBNG_00876 7.7e-157 559.7 Bifidobacteriales pyrK 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 ko:K00266,ko:K00528,ko:K02823 ko00240,ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00910,map01100,map01110,map01120,map01130,map01230 R00093,R00114,R00248,R10159 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 Bacteria 2HQ24@201174,4CZC1@85004,COG0543@1,COG0543@2 NA|NA|NA C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B LPKNPDNH_01478 398513.BBNG_00877 8.2e-179 632.9 Bifidobacteriales pyrD 1.3.1.14 ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01869 RC00051 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKC6@201174,4CYU2@85004,COG0167@1,COG0167@2 NA|NA|NA F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily LPKNPDNH_01479 398513.BBNG_00878 1.1e-124 452.6 Bifidobacteriales pyrE 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM5A@201174,4CZHB@85004,COG0461@1,COG0461@2 NA|NA|NA F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) LPKNPDNH_01480 398513.BBNG_00879 1.3e-24 118.2 Bifidobacteriales Bacteria 2HZK3@201174,4D0RM@85004,COG0789@1,COG0789@2 NA|NA|NA K MerR family regulatory protein LPKNPDNH_01481 398513.BBNG_00880 4.7e-196 690.3 Bifidobacteriales 1.1.1.1,1.1.1.14 ko:K00001,ko:K00008 ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 M00014 R00623,R00754,R00875,R01896,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00085,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko00002,ko01000 Bacteria 2GISW@201174,4CZJY@85004,COG1063@1,COG1063@2 NA|NA|NA C Zinc-binding dehydrogenase LPKNPDNH_01482 398513.BBNG_00881 1.7e-143 515.8 Bifidobacteriales Bacteria 2DNFW@1,2IANA@201174,32XAQ@2,4D0ED@85004 NA|NA|NA LPKNPDNH_01484 762211.BSTEL_0299 1.9e-15 88.6 Bifidobacteriales Bacteria 2IB6I@201174,4D0BZ@85004,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase LPKNPDNH_01485 398513.BBNG_00884 0.0 1647.1 Bifidobacteriales uvrA3 ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2GNMW@201174,4CZ5X@85004,COG0178@1,COG0178@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate LPKNPDNH_01486 702459.BBPR_0948 5.2e-243 846.7 Bifidobacteriales vbsD Bacteria 2GXXK@201174,4CZU6@85004,COG0534@1,COG0534@2 NA|NA|NA V MatE LPKNPDNH_01487 702459.BBPR_0949 8.1e-131 473.0 Bifidobacteriales Bacteria 2GMGQ@201174,4CZA7@85004,COG4221@1,COG4221@2 NA|NA|NA S Enoyl-(Acyl carrier protein) reductase LPKNPDNH_01488 702459.BBPR_0950 7.9e-134 483.0 Bifidobacteriales magIII ko:K07457 ko00000 Bacteria 2ICDU@201174,4D03Q@85004,COG2231@1,COG2231@2 NA|NA|NA L endonuclease III LPKNPDNH_01489 398513.BBNG_00888 3.8e-93 347.4 Bifidobacteriales laaE Bacteria 2I8K2@201174,4D0KJ@85004,COG1695@1,COG1695@2 NA|NA|NA K Transcriptional regulator PadR-like family LPKNPDNH_01490 398513.BBNG_00889 4e-176 624.0 Bifidobacteriales ko:K07088 ko00000 Bacteria 2GMWC@201174,4D0CA@85004,COG0679@1,COG0679@2 NA|NA|NA S Membrane transport protein LPKNPDNH_01491 398513.BBNG_00890 1.1e-65 255.8 Bifidobacteriales 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 R03470 RC00938 ko00000,ko00001,ko01000 Bacteria 2IFSF@201174,4D13U@85004,COG1917@1,COG1917@2 NA|NA|NA S Cupin domain LPKNPDNH_01492 702459.BBPR_0954 7e-225 786.2 Bifidobacteriales hipA 2.7.11.1 ko:K07154 ko00000,ko01000,ko01001,ko02048 Bacteria 2IA5Z@201174,4D09R@85004,COG3550@1,COG3550@2 NA|NA|NA S HipA N-terminal domain LPKNPDNH_01493 398513.BBNG_00892 1.4e-40 171.8 Bifidobacteriales Bacteria 2IQPX@201174,4D19Q@85004,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix LPKNPDNH_01494 702459.BBPR_0956 3.1e-49 200.7 Bacteria tam GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0030798,GO:0032259,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0051704 2.1.1.144,2.1.1.197 ko:K00598,ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 iECABU_c1320.ECABU_c17460,iSDY_1059.SDY_1625,ic_1306.c1942 Bacteria COG4106@1,COG4106@2 NA|NA|NA FG trans-aconitate 2-methyltransferase activity LPKNPDNH_01495 158787.BSCA_0497 1.6e-18 98.2 Bifidobacteriales Bacteria 2A730@1,2GXVU@201174,30VYI@2,4D269@85004 NA|NA|NA LPKNPDNH_01496 702459.BBPR_0958 9.3e-101 372.9 Bifidobacteriales Bacteria 2HUE7@201174,4D0RW@85004,COG3226@1,COG3226@2 NA|NA|NA K Bacterial regulatory proteins, tetR family LPKNPDNH_01497 398513.BBNG_00895 2e-91 341.7 Bifidobacteriales Bacteria 2I65E@201174,4D2YA@85004,COG1716@1,COG1716@2 NA|NA|NA T Domain of unknown function (DUF4234) LPKNPDNH_01498 398513.BBNG_00896 1.2e-171 609.0 Bifidobacteriales cpsY Bacteria 2HZCU@201174,4CZT8@85004,COG0583@1,COG0583@2 NA|NA|NA K Bacterial regulatory helix-turn-helix protein, lysR family LPKNPDNH_01499 702459.BBPR_0961 1.5e-123 448.7 Bifidobacteriales 3.8.1.2 ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 R05287 RC00697 ko00000,ko00001,ko01000 Bacteria 2I8XE@201174,4D00B@85004,COG1011@1,COG1011@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase LPKNPDNH_01500 398513.BBNG_00898 0.0 1128.6 Bifidobacteriales nnrD GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 ko00000,ko01000 Bacteria 2GJHB@201174,4CZC5@85004,COG0062@1,COG0062@2,COG0063@1,COG0063@2 NA|NA|NA H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration LPKNPDNH_01501 702459.BBPR_0963 7.1e-141 506.5 Bifidobacteriales 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 R03470 RC00938 ko00000,ko00001,ko01000 Bacteria 2GITB@201174,4CZBK@85004,COG0599@1,COG0599@2 NA|NA|NA S Carboxymuconolactone decarboxylase family LPKNPDNH_01502 398513.BBNG_00900 1.2e-88 332.4 Bifidobacteriales dkgB Bacteria 2GJQ7@201174,4CYUN@85004,COG0656@1,COG0656@2 NA|NA|NA S Oxidoreductase, aldo keto reductase family protein LPKNPDNH_01504 398513.BBNG_00901 6.3e-287 992.6 Bifidobacteriales ugpA 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2I2G3@201174,4CYTQ@85004,COG4284@1,COG4284@2 NA|NA|NA G UTP-glucose-1-phosphate uridylyltransferase LPKNPDNH_01505 702459.BBPR_0977 0.0 1222.2 Bifidobacteriales pafB ko:K13573 ko00000,ko03051 Bacteria 2I8M5@201174,4CZWF@85004,COG2378@1,COG2378@2 NA|NA|NA K WYL domain LPKNPDNH_01506 702459.BBPR_0978 7.7e-52 209.5 Bifidobacteriales Bacteria 2B5BE@1,2IQT5@201174,31Y5K@2,4D17A@85004 NA|NA|NA LPKNPDNH_01507 398513.BBNG_00904 0.0 1640.2 Bifidobacteriales helY GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 ko:K03727 ko00000,ko01000 Bacteria 2GJEX@201174,4CZEC@85004,COG4581@1,COG4581@2 NA|NA|NA L DEAD DEAH box helicase LPKNPDNH_01508 398513.BBNG_00905 3e-62 244.2 Bifidobacteriales rbpA GO:0001000,GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0043167,GO:0043169,GO:0043175,GO:0045893,GO:0045935,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 Bacteria 2CNY9@1,2IMK6@201174,32SI2@2,4D0V5@85004 NA|NA|NA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters LPKNPDNH_01509 398513.BBNG_00906 4.2e-35 153.7 Bifidobacteriales pgp GO:0003674,GO:0003824,GO:0004672,GO:0004713,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0071704,GO:0140096,GO:1901564 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 2HFGX@201174,4CYSF@85004,COG0546@1,COG0546@2 NA|NA|NA S HAD-hyrolase-like LPKNPDNH_01510 702459.BBPR_0985 4.7e-125 453.8 Bifidobacteriales Bacteria 2GN4K@201174,4D08M@85004,COG4832@1,COG4832@2 NA|NA|NA S GyrI-like small molecule binding domain LPKNPDNH_01511 702459.BBPR_0986 1.3e-96 359.0 Bacteria Bacteria COG0582@1,COG0582@2 NA|NA|NA L DNA integration LPKNPDNH_01513 398513.BBNG_00912 7.3e-62 243.0 Bifidobacteriales Bacteria 29TZI@1,2ISJH@201174,30F8H@2,4D0Z6@85004 NA|NA|NA LPKNPDNH_01514 702459.BBPR_0990 2.7e-120 438.0 Bifidobacteriales Bacteria 2GM67@201174,4CZ0X@85004,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance LPKNPDNH_01515 702459.BBPR_0991 7.3e-74 283.1 Bifidobacteriales garA Bacteria 2GK99@201174,4D0R3@85004,COG1716@1,COG1716@2 NA|NA|NA T Inner membrane component of T3SS, cytoplasmic domain LPKNPDNH_01516 398513.BBNG_00915 1e-140 506.1 Bifidobacteriales GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 Bacteria 2GJ3C@201174,4CYYH@85004,COG3879@1,COG3879@2 NA|NA|NA S Bacterial protein of unknown function (DUF881) LPKNPDNH_01517 398513.BBNG_00916 2.6e-31 141.4 Bifidobacteriales sbp Bacteria 2IKJW@201174,4D12G@85004,COG3856@1,COG3856@2 NA|NA|NA S Protein of unknown function (DUF1290) LPKNPDNH_01518 398513.BBNG_00917 1.2e-172 612.5 Bifidobacteriales GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 Bacteria 2GMS5@201174,4CZ72@85004,COG3879@1,COG3879@2 NA|NA|NA S Bacterial protein of unknown function (DUF881) LPKNPDNH_01519 398513.BBNG_00918 1e-116 426.0 Bifidobacteriales pgsA GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 Bacteria 2GM3F@201174,4CZGD@85004,COG0558@1,COG0558@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family LPKNPDNH_01520 398513.BBNG_00919 1.8e-156 558.5 Bifidobacteriales hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 Bacteria 2GNAX@201174,4CZ66@85004,COG0040@1,COG0040@2 NA|NA|NA F ATP phosphoribosyltransferase LPKNPDNH_01521 398513.BBNG_00920 6.4e-41 172.9 Bifidobacteriales hisE GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31,5.3.1.16 ko:K01523,ko:K01814,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037,R04640 RC00002,RC00945,RC01055 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_0880,iECW_1372.ECW_m2186,iEKO11_1354.EKO11_1768,iSB619.SA_RS14110,iUMN146_1321.UM146_06665,iWFL_1372.ECW_m2186,iYO844.BSU34860 Bacteria 2IQ4D@201174,4D108@85004,COG0140@1,COG0140@2 NA|NA|NA E Phosphoribosyl-ATP pyrophosphohydrolase LPKNPDNH_01522 398513.BBNG_00921 6.3e-101 373.6 Bifidobacteriales rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJZ9@201174,4CYX0@85004,COG0036@1,COG0036@2 NA|NA|NA G Ribulose-phosphate 3-epimerase LPKNPDNH_01523 398513.BBNG_00922 5.2e-192 676.8 Bifidobacteriales lgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009249,GO:0009898,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 ko:K03438,ko:K13292 ko00000,ko01000,ko03009 Bacteria 2GKSS@201174,4CYV8@85004,COG0682@1,COG0682@2 NA|NA|NA M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins LPKNPDNH_01524 398513.BBNG_00923 4.4e-163 580.5 Bifidobacteriales trpA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 2GN6T@201174,4D0A3@85004,COG0159@1,COG0159@2 NA|NA|NA E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate LPKNPDNH_01525 702459.BBPR_1001 0.0 1367.4 Bifidobacteriales trpB GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48,4.2.1.20 ko:K01609,ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722,R03508 RC00209,RC00210,RC00700,RC00701,RC00944,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM7Z@201174,4CZJW@85004,COG0133@1,COG0133@2,COG0134@1,COG0134@2 NA|NA|NA E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine LPKNPDNH_01526 398513.BBNG_00925 0.0 1382.1 Bifidobacteriales der GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0030312,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0040007,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.1.1.399,1.1.1.95,2.7.4.25 ko:K00058,ko:K00945,ko:K03977 ko00240,ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00240,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020,M00052 R00158,R00512,R01513,R01665 RC00002,RC00031 ko00000,ko00001,ko00002,ko01000,ko03009,ko04147 Bacteria 2GJ8J@201174,4CYSE@85004,COG0283@1,COG0283@2,COG1160@1,COG1160@2 NA|NA|NA F GTPase that plays an essential role in the late steps of ribosome biogenesis LPKNPDNH_01527 398513.BBNG_00926 7.5e-146 523.1 Bifidobacteriales rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 ko:K06178,ko:K06183 ko00000,ko01000,ko03009 Bacteria 2GJ4N@201174,4CZGG@85004,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family LPKNPDNH_01528 398513.BBNG_00927 1.8e-103 382.5 Bifidobacteriales glpF ko:K02440,ko:K06188 ko00000,ko02000 1.A.8,1.A.8.1,1.A.8.2 Bacteria 2HZ9W@201174,4CZ5Q@85004,COG0580@1,COG0580@2 NA|NA|NA U Belongs to the MIP aquaporin (TC 1.A.8) family LPKNPDNH_01529 398513.BBNG_00928 5.7e-30 136.7 Bifidobacteriales Bacteria 2AXAE@1,2IQKC@201174,31P9H@2,4D18B@85004 NA|NA|NA LPKNPDNH_01530 702459.BBPR_1006 0.0 1079.3 Bifidobacteriales purH GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 iHN637.CLJU_RS04230,iJN678.purH Bacteria 2GJWU@201174,4CZ3P@85004,COG0138@1,COG0138@2 NA|NA|NA F Bifunctional purine biosynthesis protein PurH LPKNPDNH_01531 398513.BBNG_00930 2.7e-244 850.9 Bifidobacteriales GO:0008150,GO:0040007 Bacteria 2EKVE@1,2HZ8H@201174,33EIZ@2,4CYRN@85004 NA|NA|NA LPKNPDNH_01532 398513.BBNG_00931 1.1e-167 595.9 Bifidobacteriales sucD GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK00@201174,4CYX1@85004,COG0074@1,COG0074@2 NA|NA|NA C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit LPKNPDNH_01533 398513.BBNG_00932 2.5e-225 787.7 Bifidobacteriales sucC 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKSB@201174,4CZCQ@85004,COG0045@1,COG0045@2 NA|NA|NA F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit LPKNPDNH_01534 398513.BBNG_00933 2.1e-100 371.7 Bifidobacteriales apt GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 Bacteria 2IM7C@201174,4CZ9H@85004,COG0503@1,COG0503@2 NA|NA|NA F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis LPKNPDNH_01535 702459.BBPR_1011 2.6e-44 184.9 Bifidobacteriales yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 2IKUJ@201174,4D139@85004,COG1862@1,COG1862@2 NA|NA|NA U Preprotein translocase subunit LPKNPDNH_01536 702459.BBPR_1012 1.8e-201 708.4 Bifidobacteriales ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJZF@201174,4CZGU@85004,COG2255@1,COG2255@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing LPKNPDNH_01537 398513.BBNG_00936 2.5e-104 384.8 Bifidobacteriales ruvA GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GN17@201174,4CZCE@85004,COG0632@1,COG0632@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB LPKNPDNH_01538 398513.BBNG_00938 1.8e-99 368.6 Bifidobacteriales ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJI5@201174,4CZ79@85004,COG0817@1,COG0817@2 NA|NA|NA L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group LPKNPDNH_01539 398513.BBNG_00939 1e-131 476.1 Bifidobacteriales yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 Bacteria 2GJ4G@201174,4CZ9X@85004,COG0217@1,COG0217@2 NA|NA|NA K transcriptional regulatory protein LPKNPDNH_01540 398513.BBNG_00940 0.0 1873.2 Bifidobacteriales 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 GH20 Bacteria 2H28J@201174,4D1SA@85004,COG3525@1,COG3525@2 NA|NA|NA M Glycosyl hydrolase family 20, catalytic domain LPKNPDNH_01541 398513.BBNG_00941 0.0 1368.2 Bifidobacteriales thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GKTC@201174,4CZD3@85004,COG0441@1,COG0441@2 NA|NA|NA J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) LPKNPDNH_01542 702459.BBPR_1021 2.2e-250 871.3 Bifidobacteriales ko:K06956 ko00000 Bacteria 2I862@201174,4D08P@85004,COG1823@1,COG1823@2 NA|NA|NA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family LPKNPDNH_01545 398513.BBNG_00943 2.6e-262 911.0 Bifidobacteriales Bacteria 2CBMG@1,2INSH@201174,33XKX@2,4D123@85004 NA|NA|NA LPKNPDNH_01549 398513.BBNG_00944 2.8e-156 557.8 Bifidobacteriales ko:K07184 ko00000 Bacteria 2GK10@201174,4CYSJ@85004,COG1938@1,COG1938@2 NA|NA|NA S PAC2 family LPKNPDNH_01550 398513.BBNG_00945 5e-168 597.0 Bifidobacteriales uppP 3.6.1.27 ko:K06153 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 2GJVG@201174,4CZ83@85004,COG1968@1,COG1968@2 NA|NA|NA V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin LPKNPDNH_01551 702459.BBPR_1025 7.1e-160 569.7 Bifidobacteriales Bacteria 2GW7W@201174,4CZ4W@85004,COG3001@1,COG3001@2 NA|NA|NA G Fructosamine kinase LPKNPDNH_01552 398513.BBNG_00947 3.4e-211 740.7 Bifidobacteriales dnaJ GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 ko:K03686 ko00000,ko03029,ko03110 Bacteria 2GK69@201174,4D03K@85004,COG0484@1,COG0484@2 NA|NA|NA O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins LPKNPDNH_01553 702459.BBPR_1027 2.3e-221 774.6 Bifidobacteriales hrcA GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K03705 ko00000,ko03000 Bacteria 2GKF5@201174,4CZK3@85004,COG1420@1,COG1420@2 NA|NA|NA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons LPKNPDNH_01554 398513.BBNG_00949 0.0 1416.7 Bifidobacteriales tkt GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ1K@201174,4CZ64@85004,COG0021@1,COG0021@2 NA|NA|NA H Belongs to the transketolase family LPKNPDNH_01555 398513.BBNG_00950 2.3e-201 708.0 Bifidobacteriales tal GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016832,GO:0044424,GO:0044464,GO:0097023 2.2.1.2 ko:K00616,ko:K08313,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 iB21_1397.B21_03781,iEC042_1314.EC042_0914,iECBD_1354.ECBD_4077,iECB_1328.ECB_03832,iECD_1391.ECD_03832,iECH74115_1262.ECH74115_5407,iECSP_1301.ECSP_5016,iECs_1301.ECs4875,iEcHS_1320.EcHS_A4181,iG2583_1286.G2583_4758,iSBO_1134.SBO_0715,iSF_1195.SF0775,iSFxv_1172.SFxv_0845,iS_1188.S0818,iZ_1308.Z5501 Bacteria 2GMF9@201174,4CZ3J@85004,COG0176@1,COG0176@2 NA|NA|NA H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway LPKNPDNH_01556 702459.BBPR_1030 1.2e-143 515.8 Bifidobacteriales yoaK Bacteria 2GKDV@201174,4CZC9@85004,COG3619@1,COG3619@2 NA|NA|NA S Protein of unknown function (DUF1275) LPKNPDNH_01557 702459.BBPR_1031 7.5e-253 879.4 Bifidobacteriales brnQ ko:K03311 ko00000 2.A.26 Bacteria 2GNMD@201174,4CZIP@85004,COG1114@1,COG1114@2 NA|NA|NA U Component of the transport system for branched-chain amino acids LPKNPDNH_01559 398513.BBNG_00955 3.1e-243 847.4 Bifidobacteriales mepA_6 Bacteria 2GXXK@201174,4D04E@85004,COG0534@1,COG0534@2 NA|NA|NA V MatE LPKNPDNH_01560 398513.BBNG_00956 6.1e-162 576.6 Bifidobacteriales Bacteria 2HZYB@201174,4CZQW@85004,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase LPKNPDNH_01561 398513.BBNG_00957 5.3e-178 630.2 Bifidobacteriales ldh GO:0003674,GO:0003824,GO:0004457,GO:0004459,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 2IASS@201174,4CZRT@85004,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily LPKNPDNH_01562 398513.BBNG_00958 8e-33 146.0 Bifidobacteriales secG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 2GR31@201174,4D16U@85004,COG1314@1,COG1314@2 NA|NA|NA U Preprotein translocase SecG subunit LPKNPDNH_01563 398513.BBNG_00959 5.3e-147 526.9 Bifidobacteriales tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GJXZ@201174,4CYSG@85004,COG0149@1,COG0149@2 NA|NA|NA G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) LPKNPDNH_01564 398513.BBNG_00960 2e-222 778.1 Bifidobacteriales pgk GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GJC6@201174,4CZJ3@85004,COG0126@1,COG0126@2 NA|NA|NA F Phosphoglycerate kinase LPKNPDNH_01565 398513.BBNG_00961 3.1e-173 614.4 Bifidobacteriales whiA GO:0008150,GO:0043937,GO:0050789,GO:0050793,GO:0065007 ko:K09762 ko00000 Bacteria 2GJZU@201174,4CYTD@85004,COG1481@1,COG1481@2 NA|NA|NA K May be required for sporulation LPKNPDNH_01566 398513.BBNG_00962 1.5e-177 628.6 Bifidobacteriales rapZ GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 ko:K06958 ko00000,ko03019 Bacteria 2GMWB@201174,4CZ70@85004,COG1660@1,COG1660@2 NA|NA|NA S Displays ATPase and GTPase activities LPKNPDNH_01567 398513.BBNG_00963 4.3e-183 647.1 Bifidobacteriales aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2552c Bacteria 2GPQQ@201174,4CZCM@85004,COG0169@1,COG0169@2 NA|NA|NA E Shikimate dehydrogenase substrate binding domain LPKNPDNH_01568 398513.BBNG_00964 0.0 1519.6 Bifidobacteriales uvrC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016787,GO:0016788,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2GIS4@201174,4CYVX@85004,COG0322@1,COG0322@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision LPKNPDNH_01569 398513.BBNG_00965 0.0 2008.8 Bifidobacteriales uvrA GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090 ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 2GJUV@201174,4CYRU@85004,COG0178@1,COG0178@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate LPKNPDNH_01570 398513.BBNG_00966 6.1e-77 293.9 Bifidobacteriales Bacteria 2B5S6@1,2I02B@201174,31YMU@2,4D2QX@85004 NA|NA|NA LPKNPDNH_01571 702459.BBPR_1045 7.1e-28 129.8 Bifidobacteriales ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GIRW@201174,4D000@85004,COG0577@1,COG0577@2 NA|NA|NA V MacB-like periplasmic core domain LPKNPDNH_01572 398513.BBNG_00968 1.9e-41 174.9 Bifidobacteriales Bacteria 2GKYV@201174,4D0I8@85004,COG0745@1,COG0745@2 NA|NA|NA K Transcriptional regulatory protein, C terminal LPKNPDNH_01573 398513.BBNG_00968 3.9e-37 160.2 Bifidobacteriales Bacteria 2GKYV@201174,4D0I8@85004,COG0745@1,COG0745@2 NA|NA|NA K Transcriptional regulatory protein, C terminal LPKNPDNH_01574 702459.BBPR_1047 1.1e-230 805.8 Bifidobacteriales qseC GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0042221,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 ko:K02484,ko:K07637,ko:K07643,ko:K07645,ko:K07649,ko:K07653,ko:K18351 ko01502,ko01503,ko02020,ko02024,map01502,map01503,map02020,map02024 M00444,M00451,M00453,M00457,M00460,M00651,M00658,M00709,M00721,M00722,M00723,M00724,M00744 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 Bacteria 2I436@201174,4D01R@85004,COG0642@1,COG0642@2 NA|NA|NA T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain LPKNPDNH_01575 398513.BBNG_00970 4.5e-140 503.8 Bifidobacteriales vanY 3.4.17.14 ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 M00651 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Bacteria 2IN2C@201174,4CZAQ@85004,COG1876@1,COG1876@2 NA|NA|NA M D-alanyl-D-alanine carboxypeptidase LPKNPDNH_01576 398513.BBNG_00972 8.9e-303 1045.4 Bifidobacteriales ybiT Bacteria 2GKQ4@201174,4CYS2@85004,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter LPKNPDNH_01577 398513.BBNG_00973 1.6e-196 691.8 Bifidobacteriales galE 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMCW@201174,4CZDB@85004,COG1087@1,COG1087@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family LPKNPDNH_01578 702459.BBPR_1051 1.1e-307 1061.6 Bifidobacteriales galT 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 2HNCF@201174,4CZT3@85004,COG4468@1,COG4468@2 NA|NA|NA G UDP-glucose--hexose-1-phosphate uridylyltransferase LPKNPDNH_01579 398513.BBNG_00975 4.8e-207 726.9 Bifidobacteriales mdsC 2.7.1.162,2.7.1.39 ko:K02204,ko:K13059 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771,R08962 RC00002,RC00017,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 2I8JD@201174,4D06K@85004,COG2334@1,COG2334@2 NA|NA|NA S Phosphotransferase enzyme family LPKNPDNH_01580 702459.BBPR_1053 6.4e-218 763.1 Bifidobacteriales Bacteria 2GKMZ@201174,4CZUF@85004,COG1940@1,COG1940@2 NA|NA|NA GK ROK family LPKNPDNH_01581 398513.BBNG_00977 1.5e-177 628.6 Bifidobacteriales 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 2GZ27@201174,4CZII@85004,COG1940@1,COG1940@2 NA|NA|NA GK ROK family LPKNPDNH_01582 702459.BBPR_1055 0.0 1568.5 Bifidobacteriales gnpA GO:0003674,GO:0003824,GO:0004645,GO:0005975,GO:0008150,GO:0008152,GO:0016740,GO:0016757,GO:0016758,GO:0044238,GO:0050500,GO:0071704 2.4.1.211 ko:K15533 ko00000,ko01000 Bacteria 2GN2A@201174,4CYZB@85004,COG5426@1,COG5426@2 NA|NA|NA S Lacto-N-biose phosphorylase C-terminal domain LPKNPDNH_01583 398513.BBNG_00980 1e-168 599.4 Bifidobacteriales ko:K02026 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 2GJPZ@201174,4CYV5@85004,COG0395@1,COG0395@2 NA|NA|NA G ABC transporter permease LPKNPDNH_01584 702459.BBPR_1057 1.4e-173 615.5 Bifidobacteriales ko:K02025,ko:K15771 ko02010,map02010 M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2 Bacteria 2GMTW@201174,4CZX2@85004,COG1175@1,COG1175@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component LPKNPDNH_01585 398513.BBNG_00982 1.2e-19 101.7 Bifidobacteriales ko:K02027 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 2GJIP@201174,4CZ88@85004,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein LPKNPDNH_01586 702459.BBPR_1058 3.7e-208 730.7 Bifidobacteriales ko:K02027 M00207 ko00000,ko00002,ko02000 3.A.1.1 Bacteria 2GJIP@201174,4CZ88@85004,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein LPKNPDNH_01587 702459.BBPR_1059 7.1e-308 1062.4 Bifidobacteriales trpE 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKJT@201174,4CZHW@85004,COG0147@1,COG0147@2 NA|NA|NA E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia LPKNPDNH_01588 398513.BBNG_00984 5.3e-74 283.5 Bifidobacteriales hisI GO:0008150,GO:0040007 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1606 Bacteria 2IKKU@201174,4D0WW@85004,COG0139@1,COG0139@2 NA|NA|NA E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP LPKNPDNH_01589 398513.BBNG_00985 1.4e-139 502.3 Bifidobacteriales hisF GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007 4.1.3.27 ko:K01657,ko:K02500 ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023,M00026 R00985,R00986,R04558 RC00010,RC01190,RC01943,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIRP@201174,4CZ8Z@85004,COG0107@1,COG0107@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit LPKNPDNH_01590 398513.BBNG_00986 2.3e-226 791.2 Bifidobacteriales rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 ko00000,ko01000,ko03009 Bacteria 2GJ48@201174,4CZG2@85004,COG0820@1,COG0820@2 NA|NA|NA J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs LPKNPDNH_01591 398513.BBNG_00987 1.8e-176 625.2 Bifidobacteriales cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41,2.7.7.67 ko:K00981,ko:K07098,ko:K19664 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799,R08966 RC00002 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1397 Bacteria 2I7ZA@201174,4CYZM@85004,COG0575@1,COG0575@2 NA|NA|NA I Cytidylyltransferase family LPKNPDNH_01592 398513.BBNG_00988 2.4e-93 348.2 Bifidobacteriales frr GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02838 ko00000,ko03012 Bacteria 2GJ9J@201174,4CYTF@85004,COG0233@1,COG0233@2 NA|NA|NA J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another LPKNPDNH_01593 398513.BBNG_00989 2.4e-133 481.5 Bifidobacteriales pyrH GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 R00158 RC00002 ko00000,ko00001,ko01000 iSB619.SA_RS06240 Bacteria 2GKWQ@201174,4CZEK@85004,COG0528@1,COG0528@2 NA|NA|NA F Catalyzes the reversible phosphorylation of UMP to UDP LPKNPDNH_01594 398513.BBNG_00990 1e-127 462.6 Bifidobacteriales 3.2.1.8 ko:K01181,ko:K06889 ko00000,ko01000 Bacteria 2HZF3@201174,4D06X@85004,COG1073@1,COG1073@2 NA|NA|NA S alpha beta LPKNPDNH_01595 398513.BBNG_00992 2.4e-145 521.5 Bifidobacteriales tsf GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02357 ko00000,ko03012,ko03029 Bacteria 2GK4M@201174,4CYVQ@85004,COG0264@1,COG0264@2 NA|NA|NA J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome LPKNPDNH_01596 398513.BBNG_00993 1.4e-145 522.3 Bifidobacteriales rpsB GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02967 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GMYC@201174,4CZ96@85004,COG0052@1,COG0052@2 NA|NA|NA J Belongs to the universal ribosomal protein uS2 family LPKNPDNH_01597 398513.BBNG_00994 5.8e-88 330.1 Bifidobacteriales def 3.5.1.88 ko:K01462 ko00000,ko01000 Bacteria 2GJ87@201174,4CZ63@85004,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions LPKNPDNH_01598 702459.BBPR_1070 0.0 1280.0 Bifidobacteriales fadD3 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 2GIXQ@201174,4CYVD@85004,COG1022@1,COG1022@2 NA|NA|NA I long-chain-fatty acid CoA ligase LPKNPDNH_01599 398513.BBNG_00996 5.7e-91 340.1 Bifidobacteriales Bacteria 2BGJW@1,2IR97@201174,32AI7@2,4D19G@85004 NA|NA|NA LPKNPDNH_01600 398513.BBNG_00997 2.5e-200 704.5 Bifidobacteriales guaB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 2GKVS@201174,4CZDK@85004,COG0516@1,COG0516@2 NA|NA|NA F IMP dehydrogenase family protein LPKNPDNH_01601 398513.BBNG_00998 2.2e-240 837.8 Bifidobacteriales icd GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GM3D@201174,4CZ8V@85004,COG0538@1,COG0538@2 NA|NA|NA C Belongs to the isocitrate and isopropylmalate dehydrogenases family LPKNPDNH_01602 398513.BBNG_00999 3.2e-276 957.2 Bifidobacteriales ko:K10439,ko:K10546 ko02010,ko02030,map02010,map02030 M00212,M00216 ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.5 Bacteria 2HZAK@201174,4CZCR@85004,COG4213@1,COG4213@2 NA|NA|NA G ABC transporter substrate-binding protein LPKNPDNH_01603 398513.BBNG_01000 0.0 1205.3 Bifidobacteriales fadD1 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 2GIXQ@201174,4CYYC@85004,COG1022@1,COG1022@2 NA|NA|NA I AMP-binding enzyme LPKNPDNH_01604 702459.BBPR_1076 7e-170 603.2 Bifidobacteriales Bacteria 2IQ64@201174,4D199@85004,COG0739@1,COG0739@2 NA|NA|NA M Peptidase family M23 LPKNPDNH_01606 398513.BBNG_01003 6.9e-195 686.4 Bifidobacteriales tsaD GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 R10648 RC00070,RC00416 ko00000,ko00001,ko00002,ko01000,ko02044,ko03016 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 2GJ98@201174,4CZ0K@85004,COG0533@1,COG0533@2 NA|NA|NA O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction LPKNPDNH_01607 398513.BBNG_01004 3.1e-104 384.4 Bifidobacteriales rimI GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017189,GO:0018193,GO:0018194,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.3.1.128,2.3.1.234 ko:K01409,ko:K03789,ko:K14742 R10648 RC00070,RC00416 ko00000,ko01000,ko03009,ko03016 Bacteria 2IM9R@201174,4D0Q0@85004,COG0454@1,COG0456@2 NA|NA|NA K FR47-like protein LPKNPDNH_01608 702459.BBPR_1080 1.5e-158 565.5 Bifidobacteriales yeaZ GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K14742 R10648 RC00070,RC00416 ko00000,ko01000,ko03016 Bacteria 2GMTM@201174,4D0A2@85004,COG1214@1,COG1214@2 NA|NA|NA O Glycoprotease family LPKNPDNH_01609 398513.BBNG_01006 3.8e-119 434.1 Bifidobacteriales ydiB GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.1.221,5.1.1.1 ko:K01775,ko:K06925,ko:K07102 ko00473,ko00520,ko01100,ko01502,map00473,map00520,map01100,map01502 R00401,R08968,R11024 RC00002,RC00078,RC00285 ko00000,ko00001,ko01000,ko01011,ko03016 Bacteria 2IKV2@201174,4D0PH@85004,COG0802@1,COG0802@2 NA|NA|NA S Threonylcarbamoyl adenosine biosynthesis protein TsaE LPKNPDNH_01610 398513.BBNG_01007 4.8e-182 643.7 Bifidobacteriales holA 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 2GNMZ@201174,4CZ07@85004,COG1466@1,COG1466@2 NA|NA|NA L DNA polymerase III delta subunit LPKNPDNH_01611 702459.BBPR_1083 0.0 1290.4 Bifidobacteriales comE ko:K02238 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 2GJGR@201174,4CZ6X@85004,COG0658@1,COG0658@2 NA|NA|NA S Competence protein LPKNPDNH_01612 702459.BBPR_1084 3.1e-84 318.5 Bifidobacteriales comEA 2.4.1.21 ko:K00703,ko:K02237,ko:K02238 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00429,M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003,ko02044 3.A.11.1,3.A.11.2 GT5 Bacteria 2IQDC@201174,4D176@85004,COG1555@1,COG1555@2 NA|NA|NA L Helix-hairpin-helix motif LPKNPDNH_01613 398513.BBNG_01010 0.0 2053.9 Bifidobacteriales leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 2GJI1@201174,4CZHV@85004,COG0495@1,COG0495@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family LPKNPDNH_01614 702459.BBPR_1086 2.6e-169 601.3 Bifidobacteriales ko:K10005 ko02010,map02010 M00233 ko00000,ko00001,ko00002,ko02000 3.A.1.3.9 Bacteria 2I9PU@201174,4D09U@85004,COG0834@1,COG0834@2 NA|NA|NA ET Bacterial periplasmic substrate-binding proteins LPKNPDNH_01615 398513.BBNG_01012 3.7e-171 607.4 Bifidobacteriales corA ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria 2HZ8V@201174,4CYWX@85004,COG0598@1,COG0598@2 NA|NA|NA P CorA-like Mg2+ transporter protein LPKNPDNH_01616 398513.BBNG_01013 3.6e-162 577.4 Bifidobacteriales 3.1.3.85,5.4.2.11,5.4.2.12 ko:K01834,ko:K15634,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 2GJYU@201174,4CZI8@85004,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family LPKNPDNH_01617 398513.BBNG_01014 3.4e-299 1033.5 Bifidobacteriales Bacteria 2GK9N@201174,4D003@85004,COG2939@1,COG2939@2 NA|NA|NA E Serine carboxypeptidase LPKNPDNH_01618 398513.BBNG_01015 0.0 2300.8 Bifidobacteriales Bacteria 2GMIP@201174,4CYWR@85004,COG4913@1,COG4913@2 NA|NA|NA S Psort location Cytoplasmic, score 8.87 LPKNPDNH_01619 702459.BBPR_1091 1.7e-108 399.4 Bifidobacteriales Bacteria 2APK1@1,2IEAB@201174,31EP8@2,4D0C3@85004 NA|NA|NA S Domain of unknown function (DUF4194) LPKNPDNH_01620 398513.BBNG_01017 8.8e-284 982.2 Bifidobacteriales Bacteria 2ETEZ@1,2HXGA@201174,33KYW@2,4CZSC@85004 NA|NA|NA S Psort location Cytoplasmic, score 8.87 LPKNPDNH_01621 702459.BBPR_1093 9e-161 572.8 Bifidobacteriales nfo GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJJQ@201174,4CZ0H@85004,COG0648@1,COG0648@2 NA|NA|NA L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin LPKNPDNH_01622 702459.BBPR_1094 1.1e-62 245.7 Bifidobacteriales yeaO Bacteria 2IQC0@201174,4D18P@85004,COG3189@1,COG3189@2 NA|NA|NA K Protein of unknown function, DUF488 LPKNPDNH_01623 398513.BBNG_01020 1.2e-114 419.1 Bifidobacteriales ydaF_1 Bacteria 2HZBU@201174,4CZN2@85004,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain LPKNPDNH_01624 398513.BBNG_01021 4.5e-88 330.5 Bifidobacteriales MA20_25245 Bacteria 2HZQT@201174,4D1A5@85004,COG0454@1,COG0456@2 NA|NA|NA K FR47-like protein LPKNPDNH_01625 398513.BBNG_01022 7e-56 223.0 Bifidobacteriales ko:K03496,ko:K22491 ko00000,ko03000,ko03036,ko04812 Bacteria 2HAHU@201174,4D2NY@85004,COG0789@1,COG0789@2 NA|NA|NA K Transcriptional regulator LPKNPDNH_01626 398513.BBNG_01023 6.9e-37 159.5 Bifidobacteriales 2.7.7.1,3.6.1.13,3.6.1.55 ko:K01515,ko:K03207,ko:K03574,ko:K08311,ko:K13522 ko00230,ko00760,ko01100,ko03018,map00230,map00760,map01100,map03018 R00137,R01054,R03005,R10816 RC00002 ko00000,ko00001,ko01000,ko03019,ko03400 Bacteria 2I0XY@201174,4D08F@85004,COG1051@1,COG1051@2 NA|NA|NA F Hydrolase of X-linked nucleoside diphosphate N terminal LPKNPDNH_01628 702459.BBPR_1101 1.2e-185 655.6 Bifidobacteriales ko:K06888 ko00000 Bacteria 2HEQC@201174,4D0EK@85004,COG3981@1,COG3981@2,COG4405@1,COG4405@2 NA|NA|NA S Acetyltransferase (GNAT) domain LPKNPDNH_01629 398513.BBNG_01028 1.6e-76 292.4 Bacteria qseC GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0042221,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 ko:K02484,ko:K07637,ko:K07643,ko:K07645,ko:K07649,ko:K07653,ko:K18351 ko01502,ko01503,ko02020,ko02024,map01502,map01503,map02020,map02024 M00444,M00451,M00453,M00457,M00460,M00651,M00658,M00709,M00721,M00722,M00723,M00724,M00744 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 Bacteria COG0642@1,COG0642@2 NA|NA|NA T Histidine kinase LPKNPDNH_01630 702459.BBPR_1104 2.9e-133 481.1 Bifidobacteriales Bacteria 2GKY8@201174,4CZPW@85004,COG2135@1,COG2135@2 NA|NA|NA S SOS response associated peptidase (SRAP) LPKNPDNH_01631 702459.BBPR_1105 4.8e-128 463.8 Bifidobacteriales Bacteria 2F5DW@1,2GVSX@201174,33XZS@2,4D292@85004 NA|NA|NA LPKNPDNH_01632 702459.BBPR_1106 4.7e-79 300.4 Bifidobacteriales MA20_22310 4.4.1.5 ko:K01759 ko00620,map00620 R02530 RC00004,RC00740 ko00000,ko00001,ko01000 Bacteria 2II51@201174,4D0XJ@85004,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily LPKNPDNH_01633 702459.BBPR_1108 1.3e-163 582.4 Bifidobacteriales rpoC Bacteria 2GKXN@201174,4D079@85004,COG0739@1,COG0739@2 NA|NA|NA M heme binding LPKNPDNH_01634 702459.BBPR_1109 3e-28 130.6 Bacteria ko:K03446,ko:K03466,ko:K03762,ko:K08217 M00701 br01600,ko00000,ko00002,ko01504,ko02000,ko03036 2.A.1.21.1,2.A.1.21.22,2.A.1.3,2.A.1.6.4,3.A.12 Bacteria COG0477@1,COG0477@2 NA|NA|NA EGP Major facilitator Superfamily LPKNPDNH_01635 398513.BBNG_01033 5.2e-101 374.0 Bifidobacteriales ko:K05820,ko:K08217 br01600,ko00000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.22,2.A.1.27 Bacteria 2I2EY@201174,4D02G@85004,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily LPKNPDNH_01637 702459.BBPR_1112 1.2e-147 529.3 Bifidobacteriales 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2IF0U@201174,4D0I9@85004,COG2865@1,COG2865@2 NA|NA|NA LPKNPDNH_01638 158787.BSCA_2281 3.5e-10 70.1 Bifidobacteriales ko:K03294 ko00000 2.A.3.2 Bacteria 2GJ75@201174,4D03M@85004,COG0531@1,COG0531@2 NA|NA|NA CE Amino acid permease LPKNPDNH_01639 702459.BBPR_1113 1.5e-95 355.5 Bifidobacteriales ypjC Bacteria 2H8Z8@201174,4D2DD@85004,COG4905@1,COG4905@2 NA|NA|NA S Putative ABC-transporter type IV LPKNPDNH_01640 398513.BBNG_01037 1.1e-109 402.5 Bifidobacteriales ycaK GO:0000166,GO:0003674,GO:0005488,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.6.5.2 ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 Bacteria 2GNY7@201174,4D008@85004,COG2249@1,COG2249@2 NA|NA|NA S NADPH-dependent FMN reductase LPKNPDNH_01641 702459.BBPR_1115 1.4e-192 678.7 Bifidobacteriales Bacteria 2H595@201174,4CZBZ@85004,COG4767@1,COG4767@2 NA|NA|NA V VanZ like family LPKNPDNH_01642 398513.BBNG_01039 1.3e-54 218.8 Bifidobacteriales Bacteria 2ISFD@201174,4D188@85004,COG0745@1,COG0745@2 NA|NA|NA KT RESPONSE REGULATOR receiver LPKNPDNH_01643 398513.BBNG_01040 7.8e-70 269.6 Bifidobacteriales pdxH ko:K07006 ko00000 Bacteria 2IJK2@201174,4D0W8@85004,COG3576@1,COG3576@2 NA|NA|NA S Pfam:Pyridox_oxidase LPKNPDNH_01644 702459.BBPR_1118 5.9e-142 510.4 Bifidobacteriales yijF ko:K09974 ko00000 Bacteria 2IBMJ@201174,4CZM2@85004,COG3738@1,COG3738@2 NA|NA|NA S Domain of unknown function (DUF1287) LPKNPDNH_01645 398513.BBNG_01042 5e-133 480.3 Bifidobacteriales Bacteria 2GP9P@201174,4CZGH@85004,COG0778@1,COG0778@2 NA|NA|NA C Putative TM nitroreductase LPKNPDNH_01646 398513.BBNG_01043 3e-93 349.0 Bifidobacteriales Bacteria 2DQFC@1,2I8B6@201174,336HV@2,4D309@85004 NA|NA|NA LPKNPDNH_01648 398513.BBNG_01044 3.2e-255 887.1 Bifidobacteriales nplT 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 R02108,R02112,R11262 ko00000,ko00001,ko01000 GH13 Bacteria 2GJUT@201174,4D075@85004,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain LPKNPDNH_01649 398513.BBNG_01045 1.3e-78 298.9 Bifidobacteriales Bacteria 2IFD2@201174,4D0RX@85004,COG3428@1,COG3428@2 NA|NA|NA S Bacterial PH domain LPKNPDNH_01650 702459.BBPR_1123 2.7e-137 494.6 Bifidobacteriales 3.1.3.85,5.4.2.11,5.4.2.12 ko:K01834,ko:K15634,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 2GJYU@201174,4CYXK@85004,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family LPKNPDNH_01651 398513.BBNG_01047 1.2e-68 265.8 Bifidobacteriales rsfS GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 2.7.7.18 ko:K00969,ko:K09710 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03009 Bacteria 2IKZ3@201174,4D11U@85004,COG0799@1,COG0799@2 NA|NA|NA J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation LPKNPDNH_01652 398513.BBNG_01048 2.1e-263 914.4 Bifidobacteriales glmU GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030203,GO:0030260,GO:0033692,GO:0034637,GO:0034645,GO:0035635,GO:0040007,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042,ko:K11528,ko:K16203 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000,ko01002 3.A.1.5.2 iJN678.glmU,iLJ478.TM1629 Bacteria 2GJS1@201174,4CZ4C@85004,COG1207@1,COG1207@2 NA|NA|NA M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain LPKNPDNH_01654 702459.BBPR_1126 9.1e-192 676.0 Bifidobacteriales prs GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ9S@201174,4CYRD@85004,COG0462@1,COG0462@2 NA|NA|NA F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) LPKNPDNH_01655 702459.BBPR_1127 4.7e-145 520.4 Bifidobacteriales nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 ko:K00969,ko:K03574 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 2GMFZ@201174,4CZ82@85004,COG1057@1,COG1057@2 NA|NA|NA H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) LPKNPDNH_01656 398513.BBNG_01051 6.8e-93 346.7 Bifidobacteriales Bacteria 2A13J@1,2GKGD@201174,30P9F@2,4D0QR@85004 NA|NA|NA LPKNPDNH_01657 398513.BBNG_01052 1.4e-237 828.6 Bifidobacteriales proA GO:0003674,GO:0003824,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0293,iNJ661.Rv2427c,iYO844.BSU13130 Bacteria 2GISA@201174,4CZ2H@85004,COG0014@1,COG0014@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate LPKNPDNH_01658 702459.BBPR_1130 1.9e-283 981.1 Bifidobacteriales thrC 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS16355,iIT341.HP0098 Bacteria 2GIRY@201174,4CYS0@85004,COG0498@1,COG0498@2 NA|NA|NA E Threonine synthase N terminus LPKNPDNH_01659 702459.BBPR_1131 4e-122 444.1 Bifidobacteriales Bacteria 2B3RX@1,2IRDS@201174,31PYJ@2,4D16Y@85004 NA|NA|NA S ABC-2 family transporter protein LPKNPDNH_01660 398513.BBNG_01055 2.8e-126 458.0 Bifidobacteriales Bacteria 2ARYF@1,2IK3T@201174,31HAF@2,4D0YH@85004 NA|NA|NA S ABC-2 family transporter protein LPKNPDNH_01661 702459.BBPR_1133 2.7e-177 627.9 Bifidobacteriales ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GRE8@201174,4CZBH@85004,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities LPKNPDNH_01662 398513.BBNG_01057 3.7e-58 230.7 Bifidobacteriales ko:K07978,ko:K07979 ko00000,ko03000 Bacteria 2IQEW@201174,4D152@85004,COG1725@1,COG1725@2 NA|NA|NA K helix_turn_helix gluconate operon transcriptional repressor LPKNPDNH_01663 398513.BBNG_01058 2e-123 448.4 Bifidobacteriales Bacteria 2I362@201174,4CZ8D@85004,COG0637@1,COG0637@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase LPKNPDNH_01664 398513.BBNG_01059 3.5e-292 1010.4 Bifidobacteriales recN GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0030312,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 ko:K03631,ko:K13582 ko04112,map04112 ko00000,ko00001,ko03400 Bacteria 2GIVG@201174,4CYYF@85004,COG0497@1,COG0497@2 NA|NA|NA L May be involved in recombinational repair of damaged DNA LPKNPDNH_01665 398513.BBNG_01060 4.8e-182 643.7 Bifidobacteriales nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 R00104 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 2GKM2@201174,4CYZ0@85004,COG0061@1,COG0061@2 NA|NA|NA H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP LPKNPDNH_01666 398513.BBNG_01061 9.5e-235 819.3 Bifidobacteriales trkB ko:K03498 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 2GKKS@201174,4CZH7@85004,COG0168@1,COG0168@2 NA|NA|NA P Cation transport protein LPKNPDNH_01667 702459.BBPR_1139 6.8e-116 423.3 Bifidobacteriales trkA ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 2IA09@201174,4CZVT@85004,COG0569@1,COG0569@2 NA|NA|NA P TrkA-N domain LPKNPDNH_01668 702459.BBPR_1140 1.6e-99 369.0 Bifidobacteriales Bacteria 2B0CX@1,2GR13@201174,31SQ3@2,4D1JN@85004 NA|NA|NA LPKNPDNH_01669 702459.BBPR_1141 3.6e-137 494.2 Bifidobacteriales tlyA GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 ko:K06442 ko00000,ko01000,ko03009 Bacteria 2GJVT@201174,4CZSS@85004,COG1189@1,COG1189@2 NA|NA|NA J Ribosomal RNA large subunit methyltransferase J LPKNPDNH_01671 702459.BBPR_1143 7.3e-189 666.4 Bifidobacteriales yutF GO:0000121,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009987,GO:0016042,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030145,GO:0042578,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0046434,GO:0046475,GO:0046486,GO:0046503,GO:0046872,GO:0046914,GO:0046983,GO:0050897,GO:0071704,GO:1901575 3.1.3.41 ko:K01101 ko00627,ko01120,map00627,map01120 R03024 RC00151 ko00000,ko00001,ko01000 Bacteria 2GK7V@201174,4CZ1Z@85004,COG0647@1,COG0647@2 NA|NA|NA G Haloacid dehalogenase-like hydrolase LPKNPDNH_01672 702459.BBPR_1144 3.6e-159 568.5 Bifidobacteriales Bacteria 2GKX5@201174,4CYXN@85004,COG0457@1,COG0457@2 NA|NA|NA L Tetratricopeptide repeat LPKNPDNH_01673 398513.BBNG_01068 1.7e-254 884.8 Bifidobacteriales tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 2GJPR@201174,4CZKG@85004,COG0162@1,COG0162@2 NA|NA|NA J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) LPKNPDNH_01674 398513.BBNG_01069 3.5e-143 514.2 Bifidobacteriales Bacteria 2IA3M@201174,4CZY7@85004,COG4905@1,COG4905@2 NA|NA|NA S Putative ABC-transporter type IV LPKNPDNH_01675 702459.BBPR_1147 7.2e-109 399.8 Bifidobacteriales 6.1.1.14 ko:K01879,ko:K06950 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2IFXP@201174,4D0P2@85004,COG1418@1,COG1418@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. LPKNPDNH_01676 702459.BBPR_1148 1.4e-281 974.9 Bifidobacteriales argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 iJN678.argH Bacteria 2GJ2A@201174,4CZ50@85004,COG0165@1,COG0165@2 NA|NA|NA E argininosuccinate lyase LPKNPDNH_01677 702459.BBPR_1149 0.0 2206.4 Bifidobacteriales hsdR 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 2HI69@201174,4CZER@85004,COG0610@1,COG0610@2 NA|NA|NA V Subunit R is required for both nuclease and ATPase activities, but not for modification LPKNPDNH_01678 398513.BBNG_01073 4.3e-270 936.8 Bifidobacteriales Bacteria 2GP7C@201174,4CZRD@85004,COG2865@1,COG2865@2 NA|NA|NA K Putative DNA-binding domain LPKNPDNH_01679 702459.BBPR_1151 1.1e-106 393.7 Bifidobacteriales 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 2IPR0@201174,4D10W@85004,COG0732@1,COG0732@2 NA|NA|NA V type I restriction modification DNA specificity domain LPKNPDNH_01680 398513.BBNG_01075 0.0 1689.5 Bifidobacteriales hsdM 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 2GKAQ@201174,4CZNR@85004,COG0286@1,COG0286@2 NA|NA|NA V modification (methylase) protein of type I restriction-modification system K03427 LPKNPDNH_01681 702459.BBPR_1153 1.2e-154 552.4 Actinobacteria Bacteria 2E89C@1,2I65F@201174,332N8@2 NA|NA|NA S Domain of unknown function (DUF4357) LPKNPDNH_01682 398513.BBNG_01077 2.4e-30 137.5 Bifidobacteriales Bacteria 2FG1A@1,2IRY7@201174,347Y1@2,4D1MK@85004 NA|NA|NA LPKNPDNH_01683 702459.BBPR_1154 1.9e-178 632.1 Bifidobacteriales Bacteria 2HUXN@201174,4CZ21@85004,COG0582@1,COG0582@2 NA|NA|NA L Phage integrase family LPKNPDNH_01684 398513.BBNG_01079 1.5e-40 172.9 Bacteria 2.1.1.72,3.1.21.3 ko:K01154,ko:K03427 ko00000,ko01000,ko02048 Bacteria COG0732@1,COG0732@2 NA|NA|NA V type I restriction modification DNA specificity domain LPKNPDNH_01685 398513.BBNG_01080 4.1e-239 833.6 Bifidobacteriales argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 iNJ661.Rv1658 Bacteria 2GK96@201174,4CZ2R@85004,COG0137@1,COG0137@2 NA|NA|NA E Belongs to the argininosuccinate synthase family. Type 1 subfamily LPKNPDNH_01686 398513.BBNG_01081 3.2e-84 317.8 Bifidobacteriales argR GO:0000820,GO:0000821,GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006259,GO:0006310,GO:0006355,GO:0006520,GO:0006521,GO:0006525,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016043,GO:0016597,GO:0019219,GO:0019222,GO:0019752,GO:0022607,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031333,GO:0031334,GO:0031406,GO:0032991,GO:0032993,GO:0033238,GO:0033241,GO:0034214,GO:0034618,GO:0034641,GO:0036094,GO:0042150,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043254,GO:0043436,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044424,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051259,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140110,GO:1900079,GO:1900081,GO:1901360,GO:1901363,GO:1901564,GO:1901605,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2000144,GO:2000282,GO:2001141 ko:K03402 ko00000,ko03000 Bacteria 2GKA5@201174,4D0VM@85004,COG1438@1,COG1438@2 NA|NA|NA K Regulates arginine biosynthesis genes LPKNPDNH_01687 398513.BBNG_01082 1.6e-182 645.2 Bifidobacteriales argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJ6H@201174,4CZGN@85004,COG0078@1,COG0078@2 NA|NA|NA E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline LPKNPDNH_01688 702459.BBPR_1158 1.9e-247 861.3 Bifidobacteriales argD GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GKE9@201174,4CZGW@85004,COG4992@1,COG4992@2 NA|NA|NA E Aminotransferase class-III LPKNPDNH_01689 398513.BBNG_01084 3.7e-179 634.0 Bifidobacteriales argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS10565,iJN678.argB,iLJ478.TM1784 Bacteria 2GKDS@201174,4CYYX@85004,COG0548@1,COG0548@2 NA|NA|NA E Belongs to the acetylglutamate kinase family. ArgB subfamily LPKNPDNH_01690 398513.BBNG_01086 7.9e-216 756.1 Bifidobacteriales argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35,2.7.2.8 ko:K00620,ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282,R02649 RC00002,RC00004,RC00043,RC00064 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIW0@201174,4CZQQ@85004,COG1364@1,COG1364@2 NA|NA|NA E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate LPKNPDNH_01691 398513.BBNG_01087 1.1e-203 715.7 Bifidobacteriales argC GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKQK@201174,4CZNC@85004,COG0002@1,COG0002@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde LPKNPDNH_01692 398513.BBNG_01088 5.1e-87 327.4 Bifidobacteriales Bacteria 2AHAX@1,2IPJ5@201174,317M8@2,4D11M@85004 NA|NA|NA LPKNPDNH_01693 398513.BBNG_01089 0.0 1741.1 Bifidobacteriales pheT GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GMFD@201174,4CYUM@85004,COG0072@1,COG0072@2,COG0073@1,COG0073@2 NA|NA|NA J Phenylalanyl-tRNA synthetase beta LPKNPDNH_01694 398513.BBNG_01090 3.1e-203 714.1 Bifidobacteriales pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 2GJGG@201174,4CZ78@85004,COG0016@1,COG0016@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily LPKNPDNH_01695 398513.BBNG_01092 5.4e-161 573.5 Bifidobacteriales IV02_28330 2.1.1.185,2.1.1.34 ko:K00556,ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 2GJI6@201174,4CYZQ@85004,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family LPKNPDNH_01696 702459.BBPR_1166 3.4e-135 487.6 Bifidobacteriales ybbL ko:K01990,ko:K02003,ko:K02068,ko:K05685 ko02010,map02010 M00211,M00254,M00258,M00709 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.122.1,3.A.1.122.12 Bacteria 2I8QP@201174,4CZZG@85004,COG1136@1,COG1136@2 NA|NA|NA V ATPases associated with a variety of cellular activities LPKNPDNH_01697 398513.BBNG_01094 2.5e-136 491.5 Bifidobacteriales ybbM ko:K02069 M00211 ko00000,ko00002,ko02000 9.B.25.1 Bacteria 2GMHX@201174,4CYRQ@85004,COG0390@1,COG0390@2 NA|NA|NA V Uncharacterised protein family (UPF0014) LPKNPDNH_01698 398513.BBNG_01095 3e-53 214.2 Bacteria Bacteria COG4221@1,COG4221@2 NA|NA|NA IQ oxidoreductase activity LPKNPDNH_01700 702459.BBPR_1170 6.9e-83 313.2 Bifidobacteriales Bacteria 2I65G@201174,4D2YB@85004,COG1917@1,COG1917@2 NA|NA|NA K AraC-like ligand binding domain LPKNPDNH_01701 702459.BBPR_1171 1.4e-237 828.6 Bifidobacteriales rutG GO:0003674,GO:0005215,GO:0005350,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0006810,GO:0006855,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0015205,GO:0015210,GO:0015238,GO:0015851,GO:0015855,GO:0015857,GO:0015893,GO:0016020,GO:0016021,GO:0017144,GO:0019860,GO:0022857,GO:0031224,GO:0031226,GO:0034641,GO:0042221,GO:0042493,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072527,GO:0072529,GO:0072531,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1903791,GO:1904082 ko:K02824,ko:K03458,ko:K09016 ko00000,ko02000 2.A.40,2.A.40.1.1,2.A.40.1.2,2.A.40.1.3 iECO103_1326.ECO103_1052,iECUMN_1333.ECUMN_1189 Bacteria 2GMH6@201174,4CZR8@85004,COG2233@1,COG2233@2 NA|NA|NA F Permease family LPKNPDNH_01702 398513.BBNG_01098 1.1e-158 565.8 Bifidobacteriales 3.1.3.73 ko:K02226,ko:K07814 ko00860,ko01100,map00860,map01100 M00122 R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000,ko02022 Bacteria 2GN7B@201174,4CZFM@85004,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family LPKNPDNH_01703 398513.BBNG_01099 1.6e-54 219.2 Actinobacteria estB ko:K06999 ko00000 Bacteria 2GNIF@201174,COG0400@1,COG0400@2 NA|NA|NA S Phospholipase/Carboxylesterase LPKNPDNH_01704 398513.BBNG_01100 3.2e-187 661.0 Bifidobacteriales MA20_14895 Bacteria 2GS6E@201174,4CZWB@85004,COG2855@1,COG2855@2 NA|NA|NA S Conserved hypothetical protein 698 LPKNPDNH_01705 702459.BBPR_1175 3.5e-146 524.2 Bifidobacteriales rlrG ko:K21900 ko00000,ko03000 Bacteria 2HZCS@201174,4CZT1@85004,COG0583@1,COG0583@2 NA|NA|NA K Bacterial regulatory helix-turn-helix protein, lysR family LPKNPDNH_01706 702459.BBPR_1176 2.9e-119 434.5 Bifidobacteriales 3.1.3.27 ko:K18697 ko00564,map00564 R02029 RC00017 ko00000,ko00001,ko01000 Bacteria 2GMVR@201174,4D0CF@85004,COG0560@1,COG0560@2 NA|NA|NA E haloacid dehalogenase-like hydrolase LPKNPDNH_01707 702459.BBPR_1177 1.2e-288 998.4 Bifidobacteriales 2.4.1.166 ko:K00745 ko00000,ko01000 GT2 Bacteria 2I2GT@201174,4CZ0W@85004,COG0463@1,COG0463@2,COG3613@1,COG3613@2 NA|NA|NA M Glycosyltransferase like family 2 LPKNPDNH_01709 702459.BBPR_1180 0.0 1279.2 Bifidobacteriales pbpB 2.7.11.1,3.4.16.4 ko:K03587,ko:K08384,ko:K08724,ko:K08884,ko:K12132 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01001,ko01011,ko03036 Bacteria 2IAHD@201174,4D094@85004,COG2815@1,COG2815@2 NA|NA|NA S PASTA domain LPKNPDNH_01710 398513.BBNG_01107 2.1e-125 454.9 Bifidobacteriales ypfH GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0052689 ko:K06999 ko00000 Bacteria 2I5NR@201174,4CZJQ@85004,COG0400@1,COG0400@2 NA|NA|NA S Phospholipase/Carboxylesterase LPKNPDNH_01711 398513.BBNG_01108 3.5e-73 280.8 Bifidobacteriales def2 3.5.1.31,3.5.1.88 ko:K01450,ko:K01462 ko00270,ko00630,map00270,map00630 R00653 RC00165,RC00323 ko00000,ko00001,ko01000 Bacteria 2IJQ5@201174,4D14S@85004,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins LPKNPDNH_01712 398513.BBNG_01109 2e-39 168.7 Bifidobacteriales Bacteria 2AXVJ@1,2IRBS@201174,31PWU@2,4D18S@85004 NA|NA|NA LPKNPDNH_01713 398513.BBNG_01110 1.2e-34 151.8 Bifidobacteriales yhcC ko:K07069 ko00000 Bacteria 2GTG6@201174,4D1FH@85004,COG3478@1,COG3478@2 NA|NA|NA S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) LPKNPDNH_01714 398513.BBNG_01111 1.1e-65 255.8 Bifidobacteriales Bacteria 2IKXW@201174,4D10G@85004,COG3824@1,COG3824@2 NA|NA|NA S Zincin-like metallopeptidase LPKNPDNH_01715 398513.BBNG_01112 2.7e-87 328.2 Bifidobacteriales Bacteria 2E443@1,2II6X@201174,32Z0D@2,4D0ZD@85004 NA|NA|NA S Helix-turn-helix LPKNPDNH_01716 702459.BBPR_1187 5.5e-199 700.3 Bifidobacteriales Bacteria 2HUEV@201174,4CZKS@85004,COG4260@1,COG4260@2 NA|NA|NA S Short C-terminal domain LPKNPDNH_01717 216816.GS08_04270 2.7e-22 110.9 Bifidobacteriales Bacteria 2C3F9@1,2H1CK@201174,2ZWBA@2,4D1N7@85004 NA|NA|NA LPKNPDNH_01718 398513.BBNG_01115 5.9e-148 530.4 Bifidobacteriales Bacteria 2DNFW@1,2IANA@201174,32XAQ@2,4D0ED@85004 NA|NA|NA LPKNPDNH_01719 398513.BBNG_01117 4.5e-79 300.4 Bifidobacteriales Bacteria 2E529@1,2IIU2@201174,32ZVG@2,4D0Z5@85004 NA|NA|NA K Psort location Cytoplasmic, score LPKNPDNH_01720 398513.BBNG_01118 1.1e-255 889.0 Bifidobacteriales Bacteria 2IB6I@201174,4D0BZ@85004,COG0515@1,COG0515@2 NA|NA|NA KLT Protein tyrosine kinase LPKNPDNH_01721 702459.BBPR_1191 2.5e-66 258.5 Bifidobacteriales Bacteria 2IHSV@201174,4D0ZF@85004,COG1917@1,COG1917@2 NA|NA|NA S Cupin 2, conserved barrel domain protein LPKNPDNH_01722 702459.BBPR_1192 2.3e-156 558.1 Bifidobacteriales ksgA 2.1.1.182 ko:K02528 R10716 RC00003,RC03257 ko00000,ko01000,ko03009 Bacteria 2I2II@201174,4CZIK@85004,COG0030@1,COG0030@2 NA|NA|NA J Methyltransferase domain LPKNPDNH_01723 398513.BBNG_01121 5.6e-59 233.4 Bifidobacteriales yccF Bacteria 2IKS5@201174,4D11K@85004,COG3304@1,COG3304@2 NA|NA|NA S Inner membrane component domain LPKNPDNH_01724 702459.BBPR_1194 2.3e-120 438.3 Bifidobacteriales Bacteria 2I61X@201174,4D2U1@85004,COG1246@1,COG1246@2 NA|NA|NA E Psort location Cytoplasmic, score 8.87 LPKNPDNH_01725 702459.BBPR_1195 6.3e-246 856.3 Bifidobacteriales XK27_00240 Bacteria 2HZGJ@201174,4D0D3@85004,COG1510@1,COG1510@2,COG3177@1,COG3177@2 NA|NA|NA K Fic/DOC family LPKNPDNH_01726 398513.BBNG_01125 1.4e-201 708.8 Bifidobacteriales ychF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 ko:K06942 ko00000,ko03009 Bacteria 2GIXI@201174,4CZBU@85004,COG0012@1,COG0012@2 NA|NA|NA J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner LPKNPDNH_01727 702459.BBPR_1197 8.4e-229 799.3 Bifidobacteriales mtnE GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009987,GO:0016740,GO:0016769,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249 2.6.1.83 ko:K08969,ko:K10206,ko:K19549 ko00270,ko00300,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map01100,map01110,map01130,map01230 M00034,M00527,M00787 R07396,R07613,R11068 RC00006,RC01847 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 2GJ7R@201174,4CZCF@85004,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase class I and II LPKNPDNH_01728 702459.BBPR_1198 2.9e-93 348.2 Bifidobacteriales metI ko:K02072 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 2GY65@201174,4CZWG@85004,COG2011@1,COG2011@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component LPKNPDNH_01729 702459.BBPR_1199 7.5e-203 713.0 Bifidobacteriales metN ko:K02071 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 2GJ9P@201174,4CZYI@85004,COG1135@1,COG1135@2 NA|NA|NA P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system LPKNPDNH_01730 702459.BBPR_1200 7.8e-183 646.4 Actinobacteria 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2GKFE@201174,COG0022@1,COG0022@2 NA|NA|NA C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit LPKNPDNH_01731 398513.BBNG_01129 3.8e-187 660.6 Actinobacteria acoA 1.2.4.1 ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 2I3T8@201174,COG1071@1,COG1071@2 NA|NA|NA C Dehydrogenase E1 component LPKNPDNH_01732 398513.BBNG_01130 2.7e-146 524.6 Bifidobacteriales ko:K02073 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 2GMNI@201174,4CZNB@85004,COG1464@1,COG1464@2 NA|NA|NA P NLPA lipoprotein LPKNPDNH_01733 398513.BBNG_01132 1.6e-166 592.0 Bifidobacteriales iaaA 3.4.19.5,3.5.1.1 ko:K01424,ko:K13051 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 R00485 RC00010,RC02798 ko00000,ko00001,ko01000,ko01002 Bacteria 2IDMF@201174,4D073@85004,COG1446@1,COG1446@2 NA|NA|NA E Asparaginase LPKNPDNH_01734 702459.BBPR_1205 2.7e-143 514.6 Bifidobacteriales proC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0899,iIT341.HP1158 Bacteria 2GJ7D@201174,4CZIV@85004,COG0345@1,COG0345@2 NA|NA|NA E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline LPKNPDNH_01735 702459.BBPR_1206 1.9e-264 917.9 Bifidobacteriales pip 3.4.11.5 ko:K01259 ko00330,map00330 R00135 ko00000,ko00001,ko01000,ko01002 Bacteria 2GK03@201174,4CZ9T@85004,COG0596@1,COG0596@2 NA|NA|NA S alpha/beta hydrolase fold LPKNPDNH_01736 702459.BBPR_1207 0.0 1457.6 Bifidobacteriales tcsS2 Bacteria 2GJEG@201174,4CZ1M@85004,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase LPKNPDNH_01737 398513.BBNG_01136 2.8e-129 468.0 Bifidobacteriales Bacteria 2GJ46@201174,4CYQW@85004,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon LPKNPDNH_01738 702459.BBPR_1210 0.0 1780.4 Bifidobacteriales phoN Bacteria 2I4ZG@201174,4CZ80@85004,COG0671@1,COG0671@2 NA|NA|NA I PAP2 superfamily LPKNPDNH_01739 702459.BBPR_1211 0.0 1548.1 Bifidobacteriales ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GJTZ@201174,4CZUR@85004,COG0577@1,COG0577@2,COG4591@1,COG4591@2 NA|NA|NA MV MacB-like periplasmic core domain LPKNPDNH_01740 398513.BBNG_01139 4e-162 577.4 Bifidobacteriales ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 2GJN6@201174,4CZ04@85004,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein LPKNPDNH_01741 702459.BBPR_1213 2.6e-252 877.5 Bifidobacteriales metY 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 Bacteria 2I2EB@201174,4CZCT@85004,COG2873@1,COG2873@2 NA|NA|NA E Aminotransferase class-V LPKNPDNH_01742 702459.BBPR_1214 1.6e-157 562.0 Bifidobacteriales Bacteria 2IGJG@201174,4D0SP@85004,COG4905@1,COG4905@2 NA|NA|NA S Putative ABC-transporter type IV LPKNPDNH_01743 398513.BBNG_01143 1.5e-166 592.0 Bifidobacteriales pdxK 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 2HS59@201174,4CYQC@85004,COG2240@1,COG2240@2 NA|NA|NA H Phosphomethylpyrimidine kinase LPKNPDNH_01744 398513.BBNG_01144 0.0 1308.9 Bifidobacteriales sdhA GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071704,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0072350,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 iE2348C_1286.E2348C_0603,iJN746.PP_4191,iPC815.YPO1111 Bacteria 2GJ45@201174,4CYT5@85004,COG1053@1,COG1053@2 NA|NA|NA C Succinate dehydrogenase flavoprotein subunit LPKNPDNH_01745 398513.BBNG_01146 4.1e-281 973.4 Bifidobacteriales dprA 5.99.1.2 ko:K03168,ko:K04096 ko00000,ko01000,ko03032,ko03400 Bacteria 2GKDA@201174,4CYVW@85004,COG0758@1,COG0758@2 NA|NA|NA LU DNA recombination-mediator protein A LPKNPDNH_01746 398513.BBNG_01147 1.9e-294 1017.7 Bifidobacteriales comM ko:K07391 ko00000 Bacteria 2GJIQ@201174,4CYUB@85004,COG0606@1,COG0606@2 NA|NA|NA O Magnesium chelatase, subunit ChlI C-terminal LPKNPDNH_01747 398513.BBNG_01148 1.1e-70 272.3 Bifidobacteriales yraN ko:K07460 ko00000 Bacteria 2IQ3X@201174,4D191@85004,COG0792@1,COG0792@2 NA|NA|NA L Belongs to the UPF0102 family LPKNPDNH_01748 398513.BBNG_01149 1.1e-181 642.5 Bifidobacteriales sdhB GO:0000104,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0022904,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 e_coli_core.b0724,iAF1260.b0724,iBWG_1329.BWG_0583,iEC042_1314.EC042_0742,iECDH10B_1368.ECDH10B_0791,iECDH1ME8569_1439.ECDH1ME8569_0683,iECUMN_1333.ECUMN_0802,iEcDH1_1363.EcDH1_2911,iJO1366.b0724,iJR904.b0724,iY75_1357.Y75_RS03765 Bacteria 2GP9C@201174,4CZWJ@85004,COG0479@1,COG0479@2 NA|NA|NA C 4Fe-4S dicluster domain LPKNPDNH_01749 398513.BBNG_01150 4.4e-118 430.6 Bifidobacteriales safC GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 Bacteria 2HXV7@201174,4CZZN@85004,COG4122@1,COG4122@2 NA|NA|NA S O-methyltransferase LPKNPDNH_01750 398513.BBNG_01151 8.4e-168 596.3 Bifidobacteriales fmt2 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 2GKJH@201174,4CZ8R@85004,COG1611@1,COG1611@2 NA|NA|NA S Belongs to the LOG family LPKNPDNH_01751 398513.BBNG_01152 1.3e-224 785.4 Bifidobacteriales nhaA ko:K03313 ko00000,ko02000 2.A.33.1 Bacteria 2GKIK@201174,4CZES@85004,COG3004@1,COG3004@2 NA|NA|NA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons LPKNPDNH_01752 398513.BBNG_01153 1.3e-234 818.5 Bifidobacteriales patB 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 Bacteria 2GJFQ@201174,4CZFH@85004,COG1168@1,COG1168@2 NA|NA|NA E Aminotransferase, class I II LPKNPDNH_01755 398513.BBNG_01154 1.3e-243 848.6 Bifidobacteriales clpX GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 Bacteria 2GJXQ@201174,4CYT6@85004,COG1219@1,COG1219@2 NA|NA|NA O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP LPKNPDNH_01756 702459.BBPR_1228 1.5e-127 462.2 Bifidobacteriales clpP GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 2GKNK@201174,4CZVF@85004,COG0740@1,COG0740@2 NA|NA|NA O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins LPKNPDNH_01757 398513.BBNG_01156 1.1e-112 412.5 Bifidobacteriales clpP 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 2GK5C@201174,4CYUU@85004,COG0740@1,COG0740@2 NA|NA|NA O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins LPKNPDNH_01758 398513.BBNG_01157 2e-253 881.3 Bifidobacteriales clcA_2 ko:K03281 ko00000 2.A.49 Bacteria 2GPPN@201174,4CZPX@85004,COG0038@1,COG0038@2 NA|NA|NA P Voltage gated chloride channel LPKNPDNH_01759 398513.BBNG_01158 2.8e-236 824.3 Bifidobacteriales tig GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 ko:K03545 ko00000 Bacteria 2GJIG@201174,4CZ6P@85004,COG0544@1,COG0544@2 NA|NA|NA D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase LPKNPDNH_01760 398513.BBNG_01159 2.7e-249 867.5 Bifidobacteriales rnd 3.1.13.5 ko:K03684 ko00000,ko01000,ko03016 Bacteria 2GKNM@201174,4CYUV@85004,COG0349@1,COG0349@2 NA|NA|NA J 3'-5' exonuclease LPKNPDNH_01761 702459.BBPR_1233 4.4e-114 417.2 Bifidobacteriales Bacteria 2B58P@1,2HZMM@201174,31Y2Q@2,4D0Y9@85004 NA|NA|NA S Protein of unknown function (DUF3000) LPKNPDNH_01762 398513.BBNG_01161 3.9e-175 620.5 Bifidobacteriales pflA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0018307,GO:0019538,GO:0033554,GO:0036211,GO:0043170,GO:0043364,GO:0043365,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070283,GO:0071704,GO:1901564 1.97.1.4 ko:K04069 R04710 ko00000,ko01000 iECOK1_1307.ECOK1_0925,iEcE24377_1341.EcE24377A_0980,iEcSMS35_1347.EcSMS35_2219,iYL1228.KPN_00930 Bacteria 2GN2B@201174,4CZ5Y@85004,COG1180@1,COG1180@2 NA|NA|NA C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine LPKNPDNH_01763 702459.BBPR_1235 0.0 1629.4 Bifidobacteriales pflB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006629,GO:0006631,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016020,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017144,GO:0019541,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0043875,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0070689,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.3.1.54 ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 R00212,R06987 RC00004,RC01181,RC02742,RC02833 ko00000,ko00001,ko01000 iECH74115_1262.ECH74115_1064,iECIAI39_1322.ECIAI39_2245,iECSP_1301.ECSP_1007,iECs_1301.ECs0986,iEcSMS35_1347.EcSMS35_2218,iEcSMS35_1347.EcSMS35_3410,iG2583_1286.G2583_1138,iSDY_1059.SDY_2358,iZ_1308.Z1248 Bacteria 2GTTT@201174,4CZ59@85004,COG1882@1,COG1882@2 NA|NA|NA C Pyruvate formate lyase-like LPKNPDNH_01764 702459.BBPR_1236 6.4e-40 169.5 Bifidobacteriales Bacteria 2EHMB@1,2HZRX@201174,33BD3@2,4D1G1@85004 NA|NA|NA LPKNPDNH_01765 398513.BBNG_01164 0.0 1150.6 Bifidobacteriales nadE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 Bacteria 2GK2C@201174,4CZ14@85004,COG0171@1,COG0171@2,COG0388@1,COG0388@2 NA|NA|NA H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source LPKNPDNH_01766 702459.BBPR_1238 2.7e-224 784.3 Bifidobacteriales ko:K01436 ko00000,ko01000,ko01002 Bacteria 2GK05@201174,4CZC6@85004,COG1473@1,COG1473@2 NA|NA|NA S Peptidase dimerisation domain LPKNPDNH_01767 398513.BBNG_01166 3.3e-87 327.8 Bacteria Bacteria COG2011@1,COG2011@2 NA|NA|NA P ABC-type metal ion transport system permease component LPKNPDNH_01768 702459.BBPR_1240 4.6e-165 587.0 Bifidobacteriales Bacteria 2HZBH@201174,4CZIQ@85004,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase LPKNPDNH_01769 702459.BBPR_1241 5.4e-103 380.2 Bifidobacteriales ppiA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030312,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0140096,GO:1901564 5.2.1.8 ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 Bacteria 2IFUE@201174,4CZSU@85004,COG0652@1,COG0652@2 NA|NA|NA G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides LPKNPDNH_01770 398513.BBNG_01196 1.1e-49 202.2 Bifidobacteriales relB ko:K07473 ko00000,ko02048 Bacteria 2GRAY@201174,4D1J9@85004,COG3077@1,COG3077@2 NA|NA|NA L RelB antitoxin LPKNPDNH_01771 398513.BBNG_01197 1.8e-68 265.0 Bifidobacteriales Bacteria 2ISK5@201174,4D1AT@85004,COG2337@1,COG2337@2 NA|NA|NA T Toxic component of a toxin-antitoxin (TA) module LPKNPDNH_01772 702459.BBPR_1244 2.5e-208 731.1 Bifidobacteriales Bacteria 2GJVS@201174,4D2G3@85004,COG3591@1,COG3591@2 NA|NA|NA E Belongs to the peptidase S1B family LPKNPDNH_01773 398513.BBNG_01199 1.4e-12 80.1 Bifidobacteriales Bacteria 2E8P5@1,2I003@201174,303PB@2,4D2GC@85004 NA|NA|NA LPKNPDNH_01774 702459.BBPR_1246 2.7e-28 130.6 Bifidobacteriales Bacteria 2B4W6@1,2GZB9@201174,31XNV@2,4D1T7@85004 NA|NA|NA LPKNPDNH_01775 398513.BBNG_01202 0.0 1527.7 Bifidobacteriales relA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.6.5,3.1.7.2 ko:K00951,ko:K01139 ko00230,map00230 R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 Bacteria 2GJYQ@201174,4CZCW@85004,COG0317@1,COG0317@2 NA|NA|NA KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance LPKNPDNH_01776 398513.BBNG_01203 2.2e-84 318.2 Bifidobacteriales dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23,4.1.1.36,6.3.2.5 ko:K01520,ko:K13038 ko00240,ko00770,ko00983,ko01100,map00240,map00770,map00983,map01100 M00053,M00120 R02100,R03269,R04231,R11896 RC00002,RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 2IHYY@201174,4CZUJ@85004,COG0756@1,COG0756@2 NA|NA|NA F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA LPKNPDNH_01777 398513.BBNG_01204 1.4e-47 195.3 Bifidobacteriales Bacteria 2ATJW@1,2I80Y@201174,3361K@2,4D10Y@85004 NA|NA|NA S Domain of unknown function (DUF4193) LPKNPDNH_01778 398513.BBNG_01205 1.4e-187 662.1 Bifidobacteriales Bacteria 29W72@1,2HZB4@201174,30HS9@2,4CZFJ@85004 NA|NA|NA S Protein of unknown function (DUF3071) LPKNPDNH_01779 398513.BBNG_01206 6.5e-237 826.2 Bifidobacteriales Bacteria 2GISU@201174,4CZCK@85004,COG1524@1,COG1524@2 NA|NA|NA S Type I phosphodiesterase / nucleotide pyrophosphatase LPKNPDNH_01780 398513.BBNG_01208 0.0 1656.0 Bifidobacteriales gyrA GO:0005575,GO:0005622,GO:0005623,GO:0009330,GO:0032991,GO:0044424,GO:0044464 5.99.1.3 ko:K02469,ko:K02621 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 2GJ2Q@201174,4CYVH@85004,COG0188@1,COG0188@2 NA|NA|NA L DNA topoisomerase (ATP-hydrolyzing) LPKNPDNH_01781 398513.BBNG_01209 0.0 3049.6 Bifidobacteriales lhr GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 ko:K03724 ko00000,ko01000,ko03400 Bacteria 2GJG3@201174,4D01F@85004,COG1201@1,COG1201@2 NA|NA|NA L DEAD DEAH box helicase LPKNPDNH_01782 1435051.BMOU_0126 3e-25 120.6 Bifidobacteriales yozG ko:K07727 ko00000,ko03000 Bacteria 2GQZM@201174,4D1EQ@85004,COG3655@1,COG3655@2 NA|NA|NA K Cro/C1-type HTH DNA-binding domain LPKNPDNH_01783 398513.BBNG_01210 3.2e-45 188.3 Bifidobacteriales Bacteria 2DU83@1,2IMPR@201174,33PAY@2,4D19W@85004 NA|NA|NA S Protein of unknown function (DUF2975) LPKNPDNH_01784 398513.BBNG_01211 8.9e-278 962.2 Bifidobacteriales aspA 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 R00490 RC00316,RC02799 ko00000,ko00001,ko01000 Bacteria 2I2HG@201174,4CZ6N@85004,COG1027@1,COG1027@2 NA|NA|NA E Fumarase C C-terminus LPKNPDNH_01785 398513.BBNG_01212 0.0 1454.9 Bifidobacteriales gyrB2 5.99.1.3 ko:K02470 ko00000,ko01000,ko03032,ko03400 Bacteria 2GM1E@201174,4CYXR@85004,COG0187@1,COG0187@2 NA|NA|NA L DNA topoisomerase (ATP-hydrolyzing) LPKNPDNH_01786 702459.BBPR_1259 4.5e-179 634.4 Bifidobacteriales sigA ko:K03086 ko00000,ko03021 Bacteria 2GK3Z@201174,4CZQC@85004,COG0568@1,COG0568@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth LPKNPDNH_01787 398513.BBNG_01214 1e-122 446.0 Bifidobacteriales Bacteria 2B5AP@1,2IF9M@201174,31Y4U@2,4D15J@85004 NA|NA|NA LPKNPDNH_01788 702459.BBPR_1261 1e-201 709.1 Bifidobacteriales crtE 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13787,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00365,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 2GJEK@201174,4CZQV@85004,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family LPKNPDNH_01789 702459.BBPR_1262 0.0 1285.0 Bifidobacteriales pknL 2.7.11.1 ko:K12132 ko00000,ko01000,ko01001 Bacteria 2GJ1J@201174,4CYTR@85004,COG0515@1,COG0515@2,COG2815@1,COG2815@2 NA|NA|NA KLT PASTA LPKNPDNH_01790 398513.BBNG_01217 1e-133 482.6 Bifidobacteriales plsC2 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 2GJ6V@201174,4CZBB@85004,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases LPKNPDNH_01791 398513.BBNG_01218 1.5e-109 402.1 Bifidobacteriales Bacteria 2AP35@1,2IBUY@201174,31E4N@2,4D0R7@85004 NA|NA|NA LPKNPDNH_01792 398513.BBNG_01219 6.4e-193 679.9 Bifidobacteriales trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 2GM4G@201174,4CZKZ@85004,COG0547@1,COG0547@2 NA|NA|NA F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) LPKNPDNH_01793 398513.BBNG_01220 3.6e-25 122.1 Bifidobacteriales secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030312,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 2GIRT@201174,4CYX6@85004,COG0653@1,COG0653@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane LPKNPDNH_01794 398513.BBNG_01220 0.0 1670.2 Bifidobacteriales secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030312,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 2GIRT@201174,4CYX6@85004,COG0653@1,COG0653@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane LPKNPDNH_01795 398513.BBNG_01221 6.7e-111 406.8 Bifidobacteriales hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 ko:K05808 ko00000,ko03009 Bacteria 2GMYF@201174,4CZ3H@85004,COG1544@1,COG1544@2 NA|NA|NA J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase LPKNPDNH_01797 702459.BBPR_1269 2.9e-87 327.8 Bifidobacteriales recX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03565 ko00000,ko03400 Bacteria 2INKM@201174,4D0Y4@85004,COG2137@1,COG2137@2 NA|NA|NA S Modulates RecA activity LPKNPDNH_01798 702459.BBPR_1270 8e-216 756.1 Bifidobacteriales recA GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043142,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 ko:K03553 ko03440,map03440 M00729 ko00000,ko00001,ko00002,ko03400 Bacteria 2GJ4P@201174,4CYYY@85004,COG0468@1,COG0468@2 NA|NA|NA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage LPKNPDNH_01799 398513.BBNG_01226 3.7e-40 170.2 Bifidobacteriales Bacteria 2EFU9@1,2GQJW@201174,339KE@2,4D16T@85004 NA|NA|NA S Protein of unknown function (DUF3046) LPKNPDNH_01800 398513.BBNG_01227 7.3e-81 306.6 Bifidobacteriales Bacteria 2I2G5@201174,4D0PT@85004,COG1426@1,COG1426@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins LPKNPDNH_01801 398513.BBNG_01228 6.5e-96 356.7 Bifidobacteriales cinA 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 R02322 RC00100 ko00000,ko00001,ko01000 Bacteria 2IQ8T@201174,4D0CM@85004,COG1546@1,COG1546@2 NA|NA|NA S Belongs to the CinA family LPKNPDNH_01802 702459.BBPR_1274 5.4e-121 440.3 Bifidobacteriales pgsA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 Bacteria 2GK5D@201174,4CZ36@85004,COG0558@1,COG0558@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family LPKNPDNH_01803 398513.BBNG_01230 0.0 1638.6 Bifidobacteriales ftsK GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K03466 ko00000,ko03036 3.A.12 Bacteria 2GK3T@201174,4CZ5T@85004,COG1674@1,COG1674@2 NA|NA|NA D FtsK SpoIIIE family protein LPKNPDNH_01804 398513.BBNG_01231 1.2e-137 495.7 Bifidobacteriales fic GO:0008150,GO:0050789,GO:0050794,GO:0051302,GO:0065007 ko:K04095 ko00000,ko03036 Bacteria 2IN0D@201174,4D03T@85004,COG2184@1,COG2184@2 NA|NA|NA D Fic/DOC family LPKNPDNH_01805 398513.BBNG_01232 6.1e-129 467.6 Bifidobacteriales miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008033,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016070,GO:0016740,GO:0016765,GO:0019222,GO:0031323,GO:0031326,GO:0032268,GO:0033554,GO:0034248,GO:0034470,GO:0034605,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043555,GO:0044237,GO:0044238,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0051716,GO:0052381,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990497,GO:2000112,GO:2000765 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 Bacteria 2GKFT@201174,4CZNS@85004,COG0324@1,COG0324@2 NA|NA|NA F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) LPKNPDNH_01806 398513.BBNG_01233 5.7e-280 969.5 Bifidobacteriales miaB 2.8.4.3 ko:K06168 R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 Bacteria 2GJEV@201174,4CZFB@85004,COG0621@1,COG0621@2 NA|NA|NA H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine LPKNPDNH_01807 398513.BBNG_01234 2.3e-72 278.5 Bifidobacteriales relA2 2.7.6.5 ko:K07816 ko00230,map00230 R00429 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 2GKF8@201174,4CYXP@85004,COG2357@1,COG2357@2 NA|NA|NA S Region found in RelA / SpoT proteins LPKNPDNH_01808 398513.BBNG_01235 7.5e-172 609.8 Bifidobacteriales ydeD Bacteria 2I8X5@201174,4D0BH@85004,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family LPKNPDNH_01809 398513.BBNG_01236 6.6e-132 476.9 Bifidobacteriales ybhL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06890 ko00000 Bacteria 2I98Y@201174,4CZIJ@85004,COG0670@1,COG0670@2 NA|NA|NA S Belongs to the BI1 family LPKNPDNH_01810 702459.BBPR_1282 1e-97 363.2 Bifidobacteriales Bacteria 2EGCD@1,2HZ8E@201174,33A46@2,4CYRF@85004 NA|NA|NA S Domain of unknown function (DUF5067) LPKNPDNH_01811 702459.BBPR_1283 1.7e-265 921.4 Bifidobacteriales Bacteria 2GNBG@201174,4CZG6@85004,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase LPKNPDNH_01812 398513.BBNG_01239 9.1e-116 422.9 Bifidobacteriales Bacteria 2GN80@201174,4CZRF@85004,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon LPKNPDNH_01813 702459.BBPR_1285 0.0 1401.7 Bifidobacteriales Bacteria 2I99F@201174,4CZ4G@85004,COG1479@1,COG1479@2 NA|NA|NA S Protein of unknown function DUF262 LPKNPDNH_01814 702459.BBPR_1286 4.4e-302 1043.1 Bifidobacteriales gmk GO:0003674,GO:0003824,GO:0004385,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046112,GO:0046128,GO:0046390,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:0072528,GO:0090407,GO:1901068,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.4.2.10,2.7.4.8,4.1.1.23 ko:K00942,ko:K01591,ko:K13421 ko00230,ko00240,ko00983,ko01100,map00230,map00240,map00983,map01100 M00050,M00051 R00332,R00965,R01870,R02090,R08231 RC00002,RC00063,RC00409,RC00611 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_2813,iHN637.CLJU_RS17585,iIT341.HP0321,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193 Bacteria 2GKWK@201174,4D2UX@85004,COG0194@1,COG0194@2,COG0284@1,COG0284@2 NA|NA|NA F Essential for recycling GMP and indirectly, cGMP LPKNPDNH_01815 398513.BBNG_01242 0.0 2217.2 Bifidobacteriales carB GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iAF1260.b0033,iBWG_1329.BWG_0031,iECDH10B_1368.ECDH10B_0034,iECDH1ME8569_1439.ECDH1ME8569_0031,iECUMN_1333.ECUMN_0034,iEcDH1_1363.EcDH1_3566,iJN746.PP_4723,iJO1366.b0033,iJR904.b0033,iPC815.YPO0482,iY75_1357.Y75_RS00170,iYL1228.KPN_00041 Bacteria 2GK5N@201174,4CZJ4@85004,COG0458@1,COG0458@2 NA|NA|NA EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain LPKNPDNH_01816 702459.BBPR_1288 1.2e-238 832.0 Bifidobacteriales carA GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955,ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1950,iNJ661.Rv1383,iUTI89_1310.UTI89_C0036,iYO844.BSU15510,ic_1306.c0040 Bacteria 2GKFA@201174,4CYQ1@85004,COG0505@1,COG0505@2 NA|NA|NA F Belongs to the CarA family LPKNPDNH_01817 398513.BBNG_01244 3.2e-84 318.2 Bifidobacteriales nusB GO:0008150,GO:0040007 ko:K03625 ko00000,ko03009,ko03021 Bacteria 2IM3D@201174,4D0WG@85004,COG0781@1,COG0781@2 NA|NA|NA K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons LPKNPDNH_01818 398513.BBNG_01245 3.3e-103 380.9 Bifidobacteriales efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02356 ko00000,ko03012 Bacteria 2GJMS@201174,4CYY6@85004,COG0231@1,COG0231@2 NA|NA|NA J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase LPKNPDNH_01820 398513.BBNG_01246 1e-191 676.0 Bifidobacteriales Bacteria 2I8QF@201174,4D2YD@85004,COG0477@1,COG2814@2 NA|NA|NA EGP Transmembrane secretion effector LPKNPDNH_01821 702459.BBPR_1292 0.0 1158.7 Bifidobacteriales Bacteria 2I65I@201174,4D2YE@85004,COG4222@1,COG4222@2 NA|NA|NA S Esterase-like activity of phytase LPKNPDNH_01822 702459.BBPR_1294 8.1e-232 809.3 Bifidobacteriales tuf GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 ko:K02358 ko00000,ko03012,ko03029,ko04147 Bacteria 2GK4T@201174,4CYY7@85004,COG0050@1,COG0050@2 NA|NA|NA J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis LPKNPDNH_01823 398513.BBNG_01249 0.0 1409.0 Bifidobacteriales fusA GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02355 ko00000,ko03012,ko03029 Bacteria 2GKB3@201174,4CYTB@85004,COG0480@1,COG0480@2 NA|NA|NA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome LPKNPDNH_01824 1437600.JDUI01000001_gene561 3.3e-80 304.3 Bifidobacteriales rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02992 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GMVW@201174,4CZQJ@85004,COG0049@1,COG0049@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA LPKNPDNH_01825 904144.AEJD01000003_gene1022 9.3e-62 242.7 Bifidobacteriales rpsL GO:0000372,GO:0000375,GO:0000376,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015935,GO:0016070,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0032991,GO:0033120,GO:0034336,GO:0034337,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043484,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02950 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IHUF@201174,4D0PK@85004,COG0048@1,COG0048@2 NA|NA|NA J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit LPKNPDNH_01827 702459.BBPR_1298 1.3e-198 698.7 Bifidobacteriales ltaE 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 Bacteria 2GJ0V@201174,4CZ7G@85004,COG2008@1,COG2008@2 NA|NA|NA E Beta-eliminating lyase LPKNPDNH_01828 398513.BBNG_01254 1.6e-227 795.0 Bifidobacteriales Bacteria 2HEH6@201174,4CZSN@85004,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferase 4-like domain LPKNPDNH_01829 398513.BBNG_01255 0.0 2275.7 Bifidobacteriales Bacteria 2IAYR@201174,4D22D@85004,COG3250@1,COG3250@2,COG5434@1,COG5434@2 NA|NA|NA M Parallel beta-helix repeats LPKNPDNH_01830 398513.BBNG_01256 3.7e-235 820.5 Bifidobacteriales purT GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008776,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016741,GO:0016742,GO:0016772,GO:0016774,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.2 ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0389,iSDY_1059.SDY_1135 Bacteria 2GMCS@201174,4CZXH@85004,COG0027@1,COG0027@2 NA|NA|NA F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate LPKNPDNH_01831 398513.BBNG_01257 3.8e-139 500.7 Bifidobacteriales purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016881,GO:0044424,GO:0044444,GO:0044464 4.1.1.21,4.3.2.2,6.3.2.6 ko:K01587,ko:K01756,ko:K01923 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04209,R04559,R04591 RC00064,RC00162,RC00379,RC00444,RC00445,RC00590 ko00000,ko00001,ko00002,ko01000 iAF1260.b2476,iB21_1397.B21_02330,iBWG_1329.BWG_2240,iE2348C_1286.E2348C_2713,iEC042_1314.EC042_2677,iEC55989_1330.EC55989_2759,iECABU_c1320.ECABU_c27880,iECBD_1354.ECBD_1213,iECB_1328.ECB_02368,iECDH10B_1368.ECDH10B_2642,iECDH1ME8569_1439.ECDH1ME8569_2402,iECDH1ME8569_1439.EcDH1_1193,iECD_1391.ECD_02368,iECED1_1282.ECED1_2911,iECH74115_1262.ECH74115_3698,iECIAI1_1343.ECIAI1_2527,iECNA114_1301.ECNA114_2561,iECO103_1326.ECO103_2988,iECO111_1330.ECO111_3199,iECO26_1355.ECO26_3522,iECOK1_1307.ECOK1_2784,iECP_1309.ECP_2490,iECS88_1305.ECS88_2658,iECSE_1348.ECSE_2760,iECSF_1327.ECSF_2329,iECSP_1301.ECSP_3415,iECUMN_1333.ECUMN_2789,iECW_1372.ECW_m2698,iECs_1301.ECs3338,iEKO11_1354.EKO11_1259,iETEC_1333.ETEC_2581,iEcDH1_1363.EcDH1_1193,iEcE24377_1341.EcE24377A_2757,iEcHS_1320.EcHS_A2607,iEcSMS35_1347.EcSMS35_2623,iEcolC_1368.EcolC_1200,iG2583_1286.G2583_2999,iJN746.PP_1240,iJO1366.b2476,iJR904.b2476,iLF82_1304.LF82_1775,iNRG857_1313.NRG857_12360,iSFV_1184.SFV_2521,iSF_1195.SF2519,iSFxv_1172.SFxv_2773,iS_1188.S2669,iSbBS512_1146.SbBS512_E2848,iUMNK88_1353.UMNK88_3071,iWFL_1372.ECW_m2698,iY75_1357.Y75_RS12925,iYL1228.KPN_02810,iZ_1308.Z3735 Bacteria 2GK3H@201174,4CZGQ@85004,COG0152@1,COG0152@2 NA|NA|NA F Belongs to the SAICAR synthetase family LPKNPDNH_01832 702459.BBPR_1303 0.0 2382.1 Bifidobacteriales purL 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 2GKG6@201174,4CZ7C@85004,COG0046@1,COG0046@2,COG0047@1,COG0047@2 NA|NA|NA F CobB/CobQ-like glutamine amidotransferase domain LPKNPDNH_01833 398513.BBNG_01259 3.3e-110 404.4 Bifidobacteriales Bacteria 2AHN4@1,2GRW7@201174,31UTU@2,4D2UA@85004 NA|NA|NA LPKNPDNH_01834 702459.BBPR_1305 2.1e-93 348.6 Bifidobacteriales Bacteria 2ADW4@1,2IEGF@201174,313N4@2,4CZI1@85004 NA|NA|NA S Protein of unknown function (DUF4230) LPKNPDNH_01835 398513.BBNG_01261 4.3e-152 543.9 Bifidobacteriales mug 3.2.2.28 ko:K03575,ko:K03649 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 2IGMS@201174,4D0QQ@85004,COG3663@1,COG3663@2 NA|NA|NA L Uracil DNA glycosylase superfamily LPKNPDNH_01836 398513.BBNG_01262 8.9e-33 145.6 Bifidobacteriales ko:K20530 ko02024,map02024 ko00000,ko00001,ko02044 3.A.7.4 Bacteria 2HZIV@201174,4D0KM@85004,COG0583@1,COG0583@2 NA|NA|NA K DNA-binding transcription factor activity LPKNPDNH_01837 398513.BBNG_01263 4.7e-69 266.9 Bifidobacteriales MA20_22310 4.4.1.5 ko:K01759 ko00620,map00620 R02530 RC00004,RC00740 ko00000,ko00001,ko01000 Bacteria 2II51@201174,4D0V7@85004,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily LPKNPDNH_01838 398513.BBNG_01264 2e-32 144.4 Bifidobacteriales Bacteria 2DTWH@1,2GUGG@201174,33MZC@2,4D1FM@85004 NA|NA|NA LPKNPDNH_01839 398513.BBNG_01265 5.5e-305 1052.7 Bifidobacteriales umuC 2.7.7.7 ko:K02346,ko:K03502,ko:K14161 ko00000,ko01000,ko03400 Bacteria 2GQX7@201174,4CZ0D@85004,COG0389@1,COG0389@2 NA|NA|NA L DNA-damage repair protein (DNA polymerase IV) K00961 LPKNPDNH_01840 398513.BBNG_01266 1.3e-292 1011.5 Bifidobacteriales purF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 iSB619.SA_RS05225 Bacteria 2GK6I@201174,4CZ89@85004,COG0034@1,COG0034@2 NA|NA|NA F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine LPKNPDNH_01841 398513.BBNG_01267 6.8e-187 659.8 Bifidobacteriales purM GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 ko:K01933,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04208 RC00090,RC00166,RC01100 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1844,iECSF_1327.ECSF_2340 Bacteria 2GJNY@201174,4CZ3K@85004,COG0150@1,COG0150@2 NA|NA|NA F Phosphoribosylformylglycinamidine cyclo-ligase LPKNPDNH_01842 398513.BBNG_01268 5.7e-236 823.2 Bifidobacteriales purD 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS05245,iYO844.BSU06530 Bacteria 2I2F5@201174,4CZ3I@85004,COG0151@1,COG0151@2 NA|NA|NA F Belongs to the GARS family LPKNPDNH_01843 702459.BBPR_1314 0.0 1457.2 Bifidobacteriales XK27_08315 Bacteria 2HVID@201174,4CZ6J@85004,COG1368@1,COG1368@2 NA|NA|NA M Psort location CytoplasmicMembrane, score 9.26 LPKNPDNH_01844 702459.BBPR_1315 1.7e-246 858.2 Bifidobacteriales Bacteria 2GP6Q@201174,4CYXF@85004,COG0627@1,COG0627@2 NA|NA|NA S Putative esterase LPKNPDNH_01845 398513.BBNG_01271 0.0 1713.7 Bifidobacteriales lysX Bacteria 2GM2C@201174,4CYW5@85004,COG2898@1,COG2898@2 NA|NA|NA S Uncharacterised conserved protein (DUF2156) LPKNPDNH_01846 702459.BBPR_1318 3.3e-161 574.3 Bifidobacteriales ko:K02077 M00244 ko00000,ko00002,ko02000 3.A.1.15 Bacteria 2GM1K@201174,4CZ99@85004,COG0803@1,COG0803@2 NA|NA|NA P Zinc-uptake complex component A periplasmic LPKNPDNH_01847 702459.BBPR_1319 8.7e-139 499.6 Bifidobacteriales Bacteria 2IB0E@201174,4CZVU@85004,COG0523@1,COG0523@2 NA|NA|NA S cobalamin synthesis protein LPKNPDNH_01848 702459.BBPR_1320 2.3e-47 194.5 Bifidobacteriales rpmB GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02902 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQAT@201174,4D18M@85004,COG0227@1,COG0227@2 NA|NA|NA J Ribosomal L28 family LPKNPDNH_01849 398513.BBNG_01275 7.5e-49 199.5 Bifidobacteriales rpsN GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02954 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IKN9@201174,4D12X@85004,COG0199@1,COG0199@2 NA|NA|NA J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site LPKNPDNH_01850 398513.BBNG_01276 7.4e-42 176.0 Bifidobacteriales rpmE2 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034224,GO:0034641,GO:0034645,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0120127,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02909 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2IQ4I@201174,4D18J@85004,COG0254@1,COG0254@2 NA|NA|NA J Ribosomal protein L31 LPKNPDNH_01851 398513.BBNG_01277 8.2e-15 85.1 Bifidobacteriales rpmJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02919 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 2GWN0@201174,4D1R1@85004,COG0257@1,COG0257@2 NA|NA|NA J Ribosomal protein L36 LPKNPDNH_01852 398513.BBNG_01278 1.9e-22 110.9 Bifidobacteriales ko:K02911 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 2B5DR@1,2HZRT@201174,31Y86@2,4D1FD@85004 NA|NA|NA J Ribosomal L32p protein family LPKNPDNH_01853 398513.BBNG_01279 1.4e-201 708.8 Bifidobacteriales ycgR ko:K07089 ko00000 Bacteria 2GJQ0@201174,4D057@85004,COG0701@1,COG0701@2 NA|NA|NA S Predicted permease LPKNPDNH_01854 398513.BBNG_01280 7.7e-154 549.7 Bifidobacteriales ko:K08986 ko00000 Bacteria 2I8JS@201174,4CZZQ@85004,COG3689@1,COG3689@2 NA|NA|NA S TIGRFAM TIGR03943 family protein LPKNPDNH_01855 702459.BBPR_1327 9.8e-45 185.7 Bifidobacteriales Bacteria 2AUUP@1,2IKU9@201174,31KHW@2,4D15K@85004 NA|NA|NA LPKNPDNH_01856 702459.BBPR_1328 4.3e-73 280.4 Bifidobacteriales zur GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K02076,ko:K03711,ko:K09823 ko02024,map02024 ko00000,ko00001,ko03000 Bacteria 2IKS3@201174,4D0XG@85004,COG0735@1,COG0735@2 NA|NA|NA P Belongs to the Fur family LPKNPDNH_01857 398513.BBNG_01283 6.2e-229 799.7 Bifidobacteriales purK 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 Bacteria 2GJCU@201174,4CYWP@85004,COG0026@1,COG0026@2 NA|NA|NA F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) LPKNPDNH_01858 398513.BBNG_01284 4.7e-85 320.5 Bifidobacteriales purE GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 iETEC_1333.ETEC_0575,iJN746.PP_5336,iPC815.YPO3076,iUTI89_1310.UTI89_C0551 Bacteria 2IFFD@201174,4CYQZ@85004,COG0041@1,COG0041@2 NA|NA|NA F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) LPKNPDNH_01859 398513.BBNG_01285 2.9e-179 634.4 Bifidobacteriales adh3 Bacteria 2GMHR@201174,4D00X@85004,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase LPKNPDNH_01860 398513.BBNG_01286 0.0 1295.8 Bifidobacteriales dxs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0008661,GO:0009058,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901363,GO:1901576,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 Bacteria 2GMFA@201174,4CZ2M@85004,COG1154@1,COG1154@2 NA|NA|NA H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) LPKNPDNH_01862 398513.BBNG_01287 1.4e-44 185.3 Bifidobacteriales ko:K06990 ko00000,ko04812 Bacteria 2I81C@201174,4D2ZX@85004,COG1355@1,COG1355@2 NA|NA|NA S Memo-like protein LPKNPDNH_01863 702459.BBPR_1334 5.8e-230 803.1 Bifidobacteriales 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 2IBZQ@201174,4D03J@85004,COG2865@1,COG2865@2 NA|NA|NA K Putative ATP-dependent DNA helicase recG C-terminal LPKNPDNH_01864 702459.BBPR_1335 3.5e-160 570.9 Bifidobacteriales Bacteria 2HY2W@201174,4D050@85004,COG1737@1,COG1737@2 NA|NA|NA K Helix-turn-helix domain, rpiR family LPKNPDNH_01865 398513.BBNG_01290 0.0 1374.4 Bifidobacteriales dnaG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 2GJFX@201174,4CYZG@85004,COG0358@1,COG0358@2 NA|NA|NA L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication LPKNPDNH_01866 398513.BBNG_01291 1.5e-247 861.7 Bifidobacteriales dgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 ko:K01129 ko00230,map00230 R01856 RC00017 ko00000,ko00001,ko01000 Bacteria 2GJ8F@201174,4CYYP@85004,COG0232@1,COG0232@2 NA|NA|NA F Phosphohydrolase-associated domain LPKNPDNH_01867 398513.BBNG_01292 1.7e-262 911.4 Bifidobacteriales alr GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006082,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008784,GO:0009058,GO:0009059,GO:0009078,GO:0009079,GO:0009252,GO:0009273,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0019842,GO:0030170,GO:0030203,GO:0030632,GO:0034645,GO:0036094,GO:0036361,GO:0040007,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047661,GO:0048037,GO:0050662,GO:0070279,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 R00401 RC00285 ko00000,ko00001,ko01000,ko01011 iEC55989_1330.EC55989_1285,iECIAI39_1322.ECIAI39_1880,iECO103_1326.ECO103_1292,iECO26_1355.ECO26_1703,iECSE_1348.ECSE_1238,iECUMN_1333.ECUMN_1479,iECW_1372.ECW_m1275,iEKO11_1354.EKO11_2666,iEcE24377_1341.EcE24377A_1335,iPC815.YPO0321,iSBO_1134.SBO_4064,iSbBS512_1146.SbBS512_E4542,iWFL_1372.ECW_m1275,iYL1228.KPN_02308,iYL1228.KPN_04440 Bacteria 2GM2Y@201174,4CZ2Q@85004,COG0787@1,COG0787@2 NA|NA|NA M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids LPKNPDNH_01868 702459.BBPR_1339 2.6e-269 934.1 Bifidobacteriales yhdG ko:K03294 ko00000 2.A.3.2 Bacteria 2GJ75@201174,4CYZA@85004,COG0531@1,COG0531@2 NA|NA|NA E aromatic amino acid transport protein AroP K03293 LPKNPDNH_01869 398513.BBNG_01294 7.1e-94 349.7 Bifidobacteriales cysE 2.3.1.178 ko:K06718 ko00260,ko01100,ko01120,map00260,map01100,map01120 M00033 R06978 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 2HBE2@201174,4CZTR@85004,COG1670@1,COG1670@2 NA|NA|NA J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins LPKNPDNH_01870 398513.BBNG_01295 1.4e-10 72.0 Bifidobacteriales luxS GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009116,GO:0009119,GO:0009372,GO:0009987,GO:0010699,GO:0016053,GO:0016829,GO:0016846,GO:0017144,GO:0019284,GO:0019752,GO:0023052,GO:0033353,GO:0034641,GO:0042278,GO:0043094,GO:0043102,GO:0043436,GO:0043768,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046128,GO:0046394,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0051704,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_2877,iPC815.YPO3300 Bacteria 2GJVF@201174,4CYZ4@85004,COG1854@1,COG1854@2 NA|NA|NA H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) LPKNPDNH_01871 398513.BBNG_01295 2.3e-92 344.7 Bifidobacteriales luxS GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009116,GO:0009119,GO:0009372,GO:0009987,GO:0010699,GO:0016053,GO:0016829,GO:0016846,GO:0017144,GO:0019284,GO:0019752,GO:0023052,GO:0033353,GO:0034641,GO:0042278,GO:0043094,GO:0043102,GO:0043436,GO:0043768,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046128,GO:0046394,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0051704,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_2877,iPC815.YPO3300 Bacteria 2GJVF@201174,4CYZ4@85004,COG1854@1,COG1854@2 NA|NA|NA H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) LPKNPDNH_01872 398513.BBNG_01296 0.0 1322.0 Bifidobacteriales recQ 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 2GJSS@201174,4CZ0I@85004,COG0514@1,COG0514@2 NA|NA|NA L ATP-dependent DNA helicase RecQ LPKNPDNH_01873 702459.BBPR_1343 4.1e-220 770.4 Bifidobacteriales metB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48,4.4.1.1,4.4.1.8 ko:K01739,ko:K01758,ko:K01760 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00338 R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366 RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000,ko04147 iNJ661.Rv1079 Bacteria 2GJ5S@201174,4CYY2@85004,COG0626@1,COG0626@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme LPKNPDNH_01874 398513.BBNG_01298 4e-192 677.2 Bifidobacteriales cbs GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 2.5.1.47,4.2.1.22 ko:K01697,ko:K01738 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00035,M00338 R00891,R00897,R01290,R03601,R04859,R04942 RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 Bacteria 2GIXE@201174,4CYQ4@85004,COG0031@1,COG0031@2 NA|NA|NA E Pyridoxal-phosphate dependent enzyme LPKNPDNH_01875 398513.BBNG_01299 4.4e-109 400.6 Bifidobacteriales Bacteria 2E55I@1,2GTND@201174,32ZYE@2,4D2F2@85004 NA|NA|NA # 1720 queries scanned # Total time (seconds): 4.51954579353 # Rate: 380.57 q/s