GCA_000750045.1 - 21 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

Region	Type	From	To	Most similar known cluster	Similarity
Region 1.1	NRPS	1	2,357

Region	Type	From	To	Most similar known cluster	Similarity
Region 5.1	NRPS	1	1,945

Region	Type	From	To	Most similar known cluster	Similarity
Region 8.1	transAT-PKS-like	1	25,799	difficidin	Polyketide + NRP	26%

Region	Type	From	To	Most similar known cluster	Similarity
Region 10.1	NRPS	1	12,005	surfactin	NRP:Lipopeptide	8%

Region	Type	From	To	Most similar known cluster	Similarity
Region 11.1	NRPS	1	14,295	fengycin	NRP	26%

Region	Type	From	To	Most similar known cluster	Similarity
Region 12.1	NRPS	1	11,100	fengycin	NRP	20%

Region	Type	From	To	Most similar known cluster	Similarity
Region 15.1	NRPS	153,076	182,290	surfactin	NRP:Lipopeptide	52%

Region	Type	From	To	Most similar known cluster	Similarity
Region 16.1	NRPS	1	26,664	surfactin	NRP:Lipopeptide	39%

Region	Type	From	To	Most similar known cluster	Similarity
Region 17.1	transAT-PKS-like	1	46,881	difficidin	Polyketide + NRP	53%
Region 17.2	T3PKS	161,867	202,967
Region 17.3	terpene	266,285	288,168
Region 17.4	NRPS	313,395	335,778	plipastatin	NRP	30%

Region	Type	From	To	Most similar known cluster	Similarity
Region 18.1	transAT-PKS	546,408	582,170	difficidin	Polyketide + NRP	40%

Region	Type	From	To	Most similar known cluster	Similarity
Region 19.1	PKS-like	65,661	106,905	butirosin A / butirosin B	Saccharide	7%
Region 19.2	terpene	188,949	209,689
Region 19.3	lanthipeptide-class-ii	330,182	359,070
Region 19.4	transAT-PKS	525,690	613,525	macrolactin H	Polyketide	100%
Region 19.5	transAT-PKS,T3PKS,NRPS	833,054	933,619	bacillaene	Polyketide + NRP	100%
Region 19.6	NRPS,transAT-PKS,betalactone	1,007,361	1,095,151	fengycin	NRP	80%

Region	Type	From	To	Most similar known cluster	Similarity
Region 20.1	other	308,894	350,312	bacilysin	Other	100%
Region 20.2	RiPP-like,NRPS	886,622	938,413	bacillibactin	NRP	100%

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	NRPS	1	2,357
Region 5.1	NRPS	1	1,945
Region 8.1	transAT-PKS-like	1	25,799	difficidin	Polyketide + NRP	26%
Region 10.1	NRPS	1	12,005	surfactin	NRP:Lipopeptide	8%
Region 11.1	NRPS	1	14,295	fengycin	NRP	26%
Region 12.1	NRPS	1	11,100	fengycin	NRP	20%
Region 15.1	NRPS	153,076	182,290	surfactin	NRP:Lipopeptide	52%
Region 16.1	NRPS	1	26,664	surfactin	NRP:Lipopeptide	39%
Region 17.1	transAT-PKS-like	1	46,881	difficidin	Polyketide + NRP	53%
Region 17.2	T3PKS	161,867	202,967
Region 17.3	terpene	266,285	288,168
Region 17.4	NRPS	313,395	335,778	plipastatin	NRP	30%
Region 18.1	transAT-PKS	546,408	582,170	difficidin	Polyketide + NRP	40%
Region 19.1	PKS-like	65,661	106,905	butirosin A / butirosin B	Saccharide	7%
Region 19.2	terpene	188,949	209,689
Region 19.3	lanthipeptide-class-ii	330,182	359,070
Region 19.4	transAT-PKS	525,690	613,525	macrolactin H	Polyketide	100%
Region 19.5	transAT-PKS,T3PKS,NRPS	833,054	933,619	bacillaene	Polyketide + NRP	100%
Region 19.6	NRPS,transAT-PKS,betalactone	1,007,361	1,095,151	fengycin	NRP	80%
Region 20.1	other	308,894	350,312	bacilysin	Other	100%
Region 20.2	RiPP-like,NRPS	886,622	938,413	bacillibactin	NRP	100%

Compact view

JQNZ01000001.1 - Region 1 - NRPS

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Location: 1 - 2,357 nt. (total: 2,357 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 2357:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (glu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

JQNZ01000005.1 - Region 1 - NRPS

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Location: 1 - 1,945 nt. (total: 1,945 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 1945:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (glu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

JQNZ01000008.1 - Region 1 - transAT-PKS-like

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Location: 1 - 25,799 nt. (total: 25,799 nt) Show pHMM detection rules used

Region on contig edge.

transAT-PKS-like: cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS) and not PKS_AT)

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core biosynthetic genes

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KnownClusterBlast

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 25799:

Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account

Polymer prediction:: (ccmal) + (mal - mal) + (ohmal - mal - mal) + (mal)
Non-colinear ordering:: ctg8_1 + ctg8_2 + ctg8_3 + ctg8_4

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

JQNZ01000010.1 - Region 1 - NRPS

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Location: 1 - 12,005 nt. (total: 12,005 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 12005:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-leu) + (val - asp)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

JQNZ01000011.1 - Region 1 - NRPS

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Location: 1 - 14,295 nt. (total: 14,295 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 14295:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-orn) + (tyr - D-thr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

JQNZ01000012.1 - Region 1 - NRPS

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Location: 1 - 11,100 nt. (total: 11,100 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 11100:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-val) + (pro - glu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

JQNZ01000016.1 - Region 1 - NRPS

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Location: 153,076 - 182,290 nt. (total: 29,215 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 153075 - 182290:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (glu - leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

JQNZ01000017.1 - Region 1 - NRPS

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Location: 1 - 26,664 nt. (total: 26,664 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 26664:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-leu) + (leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

JQNZ01000018.1 - Region 1 - transAT-PKS-like

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Location: 1 - 46,881 nt. (total: 46,881 nt) Show pHMM detection rules used

Region on contig edge.

transAT-PKS-like: cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS) and not PKS_AT)

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core biosynthetic genes

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KnownClusterBlast

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 46881:

Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account

Polymer prediction:: (ohmal - mal) + (mal - ccmal) + (mal - ohmal - mal) + (ccmal - mal)
Non-colinear ordering:: ctg17_1 + ctg17_3 + ctg17_2 + ctg17_4

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

JQNZ01000018.1 - Region 2 - T3PKS

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Location: 161,867 - 202,967 nt. (total: 41,101 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

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core biosynthetic genes

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KnownClusterBlast

Similar known gene clusters

No matches found.

JQNZ01000018.1 - Region 3 - terpene

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Location: 266,285 - 288,168 nt. (total: 21,884 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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core biosynthetic genes

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KnownClusterBlast

Similar known gene clusters

No matches found.

JQNZ01000018.1 - Region 4 - NRPS

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Location: 313,395 - 335,778 nt. (total: 22,384 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

JQNZ01000019.1 - Region 1 - transAT-PKS

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Location: 546,408 - 582,170 nt. (total: 35,763 nt) Show pHMM detection rules used

Region on contig edge.

transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))

Legend:

core biosynthetic genes

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 546407 - 582170:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ccmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

JQNZ01000020.1 - Region 1 - PKS-like

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Location: 65,661 - 106,905 nt. (total: 41,245 nt) Show pHMM detection rules used

PKS-like: (t2pks2 or ksIII)

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core biosynthetic genes

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

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JQNZ01000020.1 - Region 2 - terpene

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Location: 188,949 - 209,689 nt. (total: 20,741 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

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KnownClusterBlast

Similar known gene clusters

No matches found.

JQNZ01000020.1 - Region 3 - lanthipeptide-class-ii

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Location: 330,182 - 359,070 nt. (total: 28,889 nt) Show pHMM detection rules used

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

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Lanthipeptides

KnownClusterBlast

Lanthipeptide predictions

Lanthipeptide(s) for ctg19_354 - Putative Class II

ctg19_353 leader / core peptide: VNEKMYRFAGDLREELEEISLNEFSGG - GGAEQRGIDhaQGNDGKLCDhbLDhbWECGLCPDhbHDhbCWC
ctg19_356 leader / core peptide: MKKEFLALEVMTEEELKELAGG - DhaEADhbPMDhbVDhbPDhbDhbIDhbIPIDhaLAGCPDhbDhbKCADhaIVDhaPCND
ctg19_357 leader / core peptide: MKKDFQALTPMTEEELKNLAGG - DhaDADhbPMDhbVDhbPDhbDhbIDhbIPIDhaLAGCPDhbDhbKCADhaIVDhaPCND

Lanthipeptide(s) for ctg19_358 - Putative Class II

ctg19_353 leader / core peptide: VNEKMYRFAGDLREELEEISLNEFSGG - GGAEQRGIDhaQGNDGKLCDhbLDhbWECGLCPDhbHDhbCWC
ctg19_356 leader / core peptide: MKKEFLALEVMTEEELKELAGG - DhaEADhbPMDhbVDhbPDhbDhbIDhbIPIDhaLAGCPDhbDhbKCADhaIVDhaPCND
ctg19_357 leader / core peptide: MKKDFQALTPMTEEELKNLAGG - DhaDADhbPMDhbVDhbPDhbDhbIDhbIPIDhaLAGCPDhbDhbKCADhaIVDhaPCND
ctg19_370 leader / core peptide: MCKLCGPKKVIVTETGFGA - VFHPCPNCKDhbGDhbDLDhbPVIKRLERMVQDAKARLDARV
allorf_0358708_0358809 leader / core peptide: LSYVCHLEVNRRSQKAARLEAA - FYYRQDhaCRRWR
allorf_0355817_0356020 leader / core peptide: LIYSCCSKTSSHRLTVFSLTANTSAISFA - FDhbGLCPRDhbIPHFDhbPDhaFDhbCDhaFVVELMNHKNDhaQIADPILDha
allorf_0356036_0356110 leader / core peptide: VTSGRVNVFFC - VNLFECFDhbEDhbMDhaP

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lanthipeptides

Core peptide predictions

ctg19_353 - Class II

Cleavage pHMM score: -5.70

RODEO score: 0

Monoisotopic mass: 3433.5 Da

Molecular weight: 3435.8 Da

Number of bridges: 5

ctg19_356 - Class II

Cleavage pHMM score: 3.30

RODEO score: 0

Monoisotopic mass: 3403.7 Da

Molecular weight: 3405.9 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3423.9 Da N = 1; 3442.0 Da N = 2; 3460.0 Da N = 3; 3478.0 Da N = 4; 3496.0 Da N = 5; 3514.0 Da N = 6; 3532.1 Da N = 7; 3550.1 Da N = 8; 3568.1 Da N = 9

ctg19_357 - Class II

Cleavage pHMM score: 3.30

RODEO score: 0

Monoisotopic mass: 3389.7 Da

Molecular weight: 3391.9 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3409.9 Da N = 1; 3427.9 Da N = 2; 3446.0 Da N = 3; 3464.0 Da N = 4; 3482.0 Da N = 5; 3500.0 Da N = 6; 3518.0 Da N = 7; 3536.1 Da N = 8; 3554.1 Da N = 9

ctg19_370 - Class II

Cleavage pHMM score: -7.30

RODEO score: 0

Monoisotopic mass: 4023.2 Da

Molecular weight: 4025.7 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 4043.7 Da N = 1

allorf_0358708_0358809 - Class II

Cleavage pHMM score: -5.60

RODEO score: 0

Monoisotopic mass: 1601.8 Da

Molecular weight: 1602.8 Da

Number of bridges: 1

allorf_0355817_0356020 - Class II

Cleavage pHMM score: -6.30

RODEO score: 0

Monoisotopic mass: 4103.1 Da

Molecular weight: 4105.7 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 4123.7 Da N = 1; 4141.8 Da N = 2; 4159.8 Da N = 3; 4177.8 Da N = 4; 4195.8 Da N = 5; 4213.8 Da N = 6

allorf_0356036_0356110 - Class II

Cleavage pHMM score: -7.00

RODEO score: 0

Monoisotopic mass: 1462.7 Da

Molecular weight: 1463.7 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 1481.7 Da N = 1; 1499.7 Da N = 2

ctg19_353 - Class II

Cleavage pHMM score: -5.70

RODEO score: 0

Monoisotopic mass: 3433.5 Da

Molecular weight: 3435.8 Da

Number of bridges: 5

ctg19_356 - Class II

Cleavage pHMM score: 3.30

RODEO score: 0

Monoisotopic mass: 3403.7 Da

Molecular weight: 3405.9 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3423.9 Da N = 1; 3442.0 Da N = 2; 3460.0 Da N = 3; 3478.0 Da N = 4; 3496.0 Da N = 5; 3514.0 Da N = 6; 3532.1 Da N = 7; 3550.1 Da N = 8; 3568.1 Da N = 9

ctg19_357 - Class II

Cleavage pHMM score: 3.30

RODEO score: 0

Monoisotopic mass: 3389.7 Da

Molecular weight: 3391.9 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3409.9 Da N = 1; 3427.9 Da N = 2; 3446.0 Da N = 3; 3464.0 Da N = 4; 3482.0 Da N = 5; 3500.0 Da N = 6; 3518.0 Da N = 7; 3536.1 Da N = 8; 3554.1 Da N = 9

JQNZ01000020.1 - Region 4 - transAT-PKS

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Location: 525,690 - 613,525 nt. (total: 87,836 nt) Show pHMM detection rules used

transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))

Legend:

core biosynthetic genes

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 4, location 525689 - 613525:

Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account

Polymer prediction:: (ohmal - ccmal - ccmal) + (ccmal - mal) + (ccmal - ccmal) + (ohmal - ohmal - mal) + (ccmal - ccmal - mal) + (mal - ohmal)
Non-colinear ordering:: ctg19_571 + ctg19_572 + ctg19_575 + ctg19_573 + ctg19_577 + ctg19_574 + ctg19_576

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

JQNZ01000020.1 - Region 5 - NRPS,T3PKS,transAT-PKS

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Location: 833,054 - 933,619 nt. (total: 100,566 nt) Show pHMM detection rules used

transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)
NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 5, location 833053 - 933619:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly - ccmal - ohmal - mal) + (mal - ccmal - mal - ohmal - mal) + (mal - ccmal - ohmal) + (X - ccmal - ccmal - ccmal) + (ccmal - mal - mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg19_824

PKS_AT (4..285): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 97.9
inactive: 46.8
Methoxymalonyl-CoA: 38.6
Methylmalonyl-CoA: 24.5
Propionyl-CoA: 23.0
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg19_825

PKS_AT (7..293): mal

ATSignature: (unknown)

No matches above 50%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 35.4
inactive: 26.4
Methoxymalonyl-CoA: 14.9
Benzoyl-CoA: 14.0
Methylmalonyl-CoA: 9.2
Isobutyryl-CoA: 8.8
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg19_826

PKS_AT (4..282): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 66.7%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 87.4
inactive: 28.2
Methoxymalonyl-CoA: 24.7
Methylmalonyl-CoA: 11.7
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg19_831

Search NORINE for peptide: strict or relaxed

CAL_domain (74..476): pk

minowa: fatty_acid

Prediction, score:

fatty_acid: 26.0
NH2: 9.4
shikimic_acid: 0.0
Acetyl-CoA: 0.0
AHBA: 0.0

AMP-binding (1145..1540): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGMIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

ctg19_834

Search NORINE for peptide: strict or relaxed

AMP-binding (492..896): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVsnmAiIYK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 60% (weak)

JQNZ01000020.1 - Region 6 - NRPS,betalactone,transAT-PKS

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Location: 1,007,361 - 1,095,151 nt. (total: 87,791 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))
betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 6, location 1007360 - 1095151:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-tyr) + (ile) + (mal - asn) + (D-tyr - D-asn - gln - pro) + (D-asn - ser)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 7, location 1007360 - 1084520:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal - asn) + (D-tyr - D-asn - gln - pro) + (D-asn - ser)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 8, location 1067429 - 1095151:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-tyr) + (ile)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

JQNZ01000021.1 - Region 1 - other

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Location: 308,894 - 350,312 nt. (total: 41,419 nt) Show pHMM detection rules used

other: (LmbU or Neocarzinostat or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin or orf2_PTase)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

KnownClusterBlast

Similar known gene clusters

JQNZ01000021.1 - Region 2 - NRPS,RiPP-like

Download region GenBank file

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Location: 886,622 - 938,413 nt. (total: 51,792 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)
NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 886621 - 938413:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly - thr)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 4, location 891285 - 938413:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly - thr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form