GCA_000830595.1 - 11 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

JXHO01000008.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 2.1	terpene	22,189	44,087

JXHO01000065.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 6.1	NRPS	7,059	72,547	surfactin	NRP:Lipopeptide	82%

JXHO01000015.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 13.1	sactipeptide	15,452	37,063	subtilosin A	RiPP:Thiopeptide	100%
Region 13.2	other	40,072	81,490	bacilysin	Other	100%

JXHO01000002.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 17.1	glycocin	26,802	46,972	sublancin 168	RiPP:Lanthipeptide	100%

JXHO01000028.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 30.1	CDPS	233,437	249,142

JXHO01000029.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 31.1	terpene	117,462	138,268

JXHO01000033.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 36.1	NRPS,NRPS-like,betalactone	9,890	61,333	fengycin	NRP	93%

JXHO01000043.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 45.1	sactipeptide,ranthipeptide	27,652	50,605	sporulation killing factor	RiPP:Head-to-tailcyclized peptide	100%

JXHO01000044.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 46.1	NRPS	72,760	119,896	bacillibactin	NRP	100%

JXHO01000050.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 52.1	T3PKS	55,596	96,693

Region	Type	From	To	Most similar known cluster	Similarity
Region 2.1	terpene	22,189	44,087
Region 6.1	NRPS	7,059	72,547	surfactin	NRP:Lipopeptide	82%
Region 13.1	sactipeptide	15,452	37,063	subtilosin A	RiPP:Thiopeptide	100%
Region 13.2	other	40,072	81,490	bacilysin	Other	100%
Region 17.1	glycocin	26,802	46,972	sublancin 168	RiPP:Lanthipeptide	100%
Region 30.1	CDPS	233,437	249,142
Region 31.1	terpene	117,462	138,268
Region 36.1	NRPS,NRPS-like,betalactone	9,890	61,333	fengycin	NRP	93%
Region 45.1	sactipeptide,ranthipeptide	27,652	50,605	sporulation killing factor	RiPP:Head-to-tailcyclized peptide	100%
Region 46.1	NRPS	72,760	119,896	bacillibactin	NRP	100%
Region 52.1	T3PKS	55,596	96,693

No secondary metabolite regions were found in these records:: JXHO01000001.1; JXHO01000009.1; JXHO01000010.1; JXHO01000011.1; JXHO01000066.1; JXHO01000068.1; JXHO01000069.1; JXHO01000012.1; JXHO01000013.1; JXHO01000014.1; JXHO01000070.1; JXHO01000016.1; JXHO01000071.1; JXHO01000017.1; JXHO01000018.1; JXHO01000019.1; JXHO01000020.1; JXHO01000021.1; JXHO01000022.1; JXHO01000003.1; JXHO01000023.1; JXHO01000024.1; JXHO01000025.1; JXHO01000026.1; JXHO01000027.1; JXHO01000030.1; JXHO01000004.1; JXHO01000031.1; JXHO01000032.1; JXHO01000034.1; JXHO01000035.1; JXHO01000036.1; JXHO01000037.1; JXHO01000038.1; JXHO01000040.1; JXHO01000041.1; JXHO01000042.1; JXHO01000045.1; JXHO01000046.1; JXHO01000047.1; JXHO01000048.1; JXHO01000049.1; JXHO01000005.1; JXHO01000051.1; JXHO01000052.1; JXHO01000055.1; JXHO01000006.1; JXHO01000056.1; JXHO01000057.1; JXHO01000058.1; JXHO01000007.1; JXHO01000060.1; JXHO01000062.1

Compact view

JXHO01000008.1 - Region 1 - terpene

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Location: 22,189 - 44,087 nt. (total: 21,899 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

JXHO01000065.1 - Region 1 - NRPS

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Location: 7,059 - 72,547 nt. (total: 65,489 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 7058 - 72547:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (glu - leu) + (val - asp) + (D-leu) + (leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg6_26

Search NORINE for peptide: strict or relaxed

AMP-binding (466..867): glu

NRPSPredictor2: glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAKDLGVVDK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 100% (strong)

AMP-binding (1510..1908): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAFMMGMVFK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

AMP-binding (2550..2938): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWFLGNVVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

ctg6_28

Search NORINE for peptide: strict or relaxed

AMP-binding (470..864): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAFWIGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 100% (strong)

AMP-binding (1501..1904): asp

NRPSPredictor2: asp

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asp

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKVGHVGK
Nearest Stachelhaus code:: asp
Stachelhaus code match:: 100% (strong)

ctg6_29

Search NORINE for peptide: strict or relaxed

AMP-binding (16..292): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWFLGNVVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

ctg6_30

Search NORINE for peptide: strict or relaxed

AMP-binding (469..867): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGCVFK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

JXHO01000015.1 - Region 1 - sactipeptide

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Location: 15,452 - 37,063 nt. (total: 21,612 nt) Show pHMM detection rules used

sactipeptide: (subtilosin or thuricin or TIGR04404 or Subtilosin_A or skfc)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

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KnownClusterBlast

Sactipeptides

Similar known gene clusters

Sactipeptide predictions

Putative Sactipeptide(s)

ctg13_22 leader / core peptide: MKKAVIVENK - GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

Sactipeptides

Core peptide predictions

ctg13_22: Putative sactipeptide; RODEO score: 33.0; Core sequence, approximate: GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

JXHO01000015.1 - Region 2 - other

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Location: 40,072 - 81,490 nt. (total: 41,419 nt) Show pHMM detection rules used

other: (LmbU or Neocarzinostat or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin or orf2_PTase)

Legend:

core biosynthetic genes

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transport-related genes

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KnownClusterBlast

Similar known gene clusters

JXHO01000002.1 - Region 1 - glycocin

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Location: 26,802 - 46,972 nt. (total: 20,171 nt) Show pHMM detection rules used

glycocin: (glycocin or sublancin)

Legend:

core biosynthetic genes

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KnownClusterBlast

Similar known gene clusters

JXHO01000028.1 - Region 1 - CDPS

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Location: 233,437 - 249,142 nt. (total: 15,706 nt) Show pHMM detection rules used

Region on contig edge.

CDPS: (CDPS or cycdipepsynth)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

JXHO01000029.1 - Region 1 - terpene

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Location: 117,462 - 138,268 nt. (total: 20,807 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

JXHO01000033.1 - Region 1 - NRPS,NRPS-like,betalactone

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Location: 9,890 - 61,333 nt. (total: 51,444 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))
betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 9889 - 61333:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (glu - D-tyr)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 9889 - 57581:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (glu - D-tyr)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 20103 - 61333:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (glu - D-tyr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg36_25

Search NORINE for peptide: strict or relaxed

AMP-binding (463..864): glu

NRPSPredictor2: glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: glu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWHFGGVDK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 100% (strong)

AMP-binding (1502..1896): tyr

NRPSPredictor2: tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: tyr, bht
Single AA prediction:: tyr

Stachelhaus prediction details:

Stachelhaus sequence:: DGTITAEVAK
Nearest Stachelhaus code:: tyr
Stachelhaus code match:: 100% (strong)

ctg36_27

Search NORINE for peptide: strict or relaxed

AMP-binding (1..293): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: ile

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFYGITFK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 100% (strong)

ctg36_32

Search NORINE for peptide: strict or relaxed

AMP-binding (13..445): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: N/A
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: gclhIAApvK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 40% (weak)

JXHO01000043.1 - Region 1 - ranthipeptide,sactipeptide

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Location: 27,652 - 50,605 nt. (total: 22,954 nt) Show pHMM detection rules used

sactipeptide: (subtilosin or thuricin or TIGR04404 or Subtilosin_A or skfc)
ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

Legend:

core biosynthetic genes

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KnownClusterBlast

Sactipeptides

Similar known gene clusters

Sactipeptide predictions

Sactipeptides - No core peptides found.

Sactipeptides

Core peptide predictions

No core peptides found.

JXHO01000044.1 - Region 1 - NRPS

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Location: 72,760 - 119,896 nt. (total: 47,137 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 72759 - 119896:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly - thr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg46_93

Search NORINE for peptide: strict or relaxed

AMP-binding (463..861): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGLIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

AMP-binding (1519..1935): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

ctg46_95

Search NORINE for peptide: strict or relaxed

AMP-binding (31..435): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: PLPAQGVVNK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 100% (strong)

JXHO01000050.1 - Region 1 - T3PKS

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Location: 55,596 - 96,693 nt. (total: 41,098 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.