GCA_001286765.1 - 15 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

CYHO01000014.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 13.1	terpene	19,808	38,212

CYHO01000017.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 16.1	NRPS,transAT-PKS,betalactone	1	55,585	mycosubtilin	NRP + Polyketide	100%

CYHO01000023.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 22.1	transAT-PKS-like	1	33,351	macrolactin H	Polyketide	50%

CYHO01000032.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 31.1	NRPS	4,931	52,070	bacillibactin	NRP	100%

CYHO01000035.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 34.1	T3PKS	1	26,647

CYHO01000040.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 38.1	NRPS	73,992	101,634	surfactin	NRP:Lipopeptide	43%

CYHO01000047.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 44.1	CDPS	34,125	54,871

CYHO01000063.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 60.1	other	1	17,204	bacilysin	Other	100%

CYHO01000068.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 65.1	sactipeptide	24,188	43,648	subtilosin A	RiPP:Thiopeptide	100%

CYHO01000081.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 78.1	NRPS,transAT-PKS,T3PKS,PKS-like	282	80,495	bacillaene	Polyketide + NRP	100%

CYHO01000111.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 108.1	epipeptide	1	15,407	thailanstatin A	NRP + Polyketide	10%

CYHO01000124.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 120.1	NRPS	1	9,121	surfactin	NRP:Lipopeptide	8%

CYHO01000158.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 147.1	NRPS	1	21,686	surfactin	NRP:Lipopeptide	34%

CYHO01000169.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 154.1	terpene	1	5,946

CYHO01000179.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 162.1	transAT-PKS-like	1	7,058	difficidin	Polyketide + NRP	40%

Region	Type	From	To	Most similar known cluster	Similarity
Region 13.1	terpene	19,808	38,212
Region 16.1	NRPS,transAT-PKS,betalactone	1	55,585	mycosubtilin	NRP + Polyketide	100%
Region 22.1	transAT-PKS-like	1	33,351	macrolactin H	Polyketide	50%
Region 31.1	NRPS	4,931	52,070	bacillibactin	NRP	100%
Region 34.1	T3PKS	1	26,647
Region 38.1	NRPS	73,992	101,634	surfactin	NRP:Lipopeptide	43%
Region 44.1	CDPS	34,125	54,871
Region 60.1	other	1	17,204	bacilysin	Other	100%
Region 65.1	sactipeptide	24,188	43,648	subtilosin A	RiPP:Thiopeptide	100%
Region 78.1	NRPS,transAT-PKS,T3PKS,PKS-like	282	80,495	bacillaene	Polyketide + NRP	100%
Region 108.1	epipeptide	1	15,407	thailanstatin A	NRP + Polyketide	10%
Region 120.1	NRPS	1	9,121	surfactin	NRP:Lipopeptide	8%
Region 147.1	NRPS	1	21,686	surfactin	NRP:Lipopeptide	34%
Region 154.1	terpene	1	5,946
Region 162.1	transAT-PKS-like	1	7,058	difficidin	Polyketide + NRP	40%

No secondary metabolite regions were found in these records:: CYHO01000001.1; CYHO01000002.1; CYHO01000003.1; CYHO01000004.1; CYHO01000005.1; CYHO01000006.1; CYHO01000007.1; CYHO01000009.1; CYHO01000010.1; CYHO01000011.1; CYHO01000012.1; CYHO01000013.1; CYHO01000015.1; CYHO01000016.1; CYHO01000018.1; CYHO01000019.1; CYHO01000020.1; CYHO01000021.1; CYHO01000022.1; CYHO01000024.1; CYHO01000025.1; CYHO01000026.1; CYHO01000027.1; CYHO01000028.1; CYHO01000029.1; CYHO01000030.1; CYHO01000031.1; CYHO01000033.1; CYHO01000034.1; CYHO01000036.1; CYHO01000038.1; CYHO01000039.1; CYHO01000041.1; CYHO01000042.1; CYHO01000043.1; CYHO01000044.1; CYHO01000046.1; CYHO01000048.1; CYHO01000049.1; CYHO01000050.1; CYHO01000051.1; CYHO01000052.1; CYHO01000053.1; CYHO01000054.1; CYHO01000055.1; CYHO01000056.1; CYHO01000057.1; CYHO01000058.1; CYHO01000059.1; CYHO01000060.1; CYHO01000061.1; CYHO01000062.1; CYHO01000064.1; CYHO01000065.1; CYHO01000066.1; CYHO01000067.1; CYHO01000069.1; CYHO01000070.1; CYHO01000071.1; CYHO01000072.1; CYHO01000073.1; CYHO01000074.1; CYHO01000075.1; CYHO01000076.1; CYHO01000077.1; CYHO01000078.1; CYHO01000079.1; CYHO01000080.1; CYHO01000082.1; CYHO01000083.1; CYHO01000084.1; CYHO01000085.1; CYHO01000086.1; CYHO01000087.1; CYHO01000088.1; CYHO01000089.1; CYHO01000090.1; CYHO01000091.1; CYHO01000092.1; CYHO01000093.1; CYHO01000094.1; CYHO01000095.1; CYHO01000096.1; CYHO01000097.1; CYHO01000098.1; CYHO01000099.1; CYHO01000100.1; CYHO01000101.1; CYHO01000102.1; CYHO01000103.1; CYHO01000104.1; CYHO01000105.1; CYHO01000106.1; CYHO01000107.1; CYHO01000108.1; CYHO01000109.1; CYHO01000110.1; CYHO01000112.1; CYHO01000113.1; CYHO01000114.1; CYHO01000115.1; CYHO01000116.1; CYHO01000117.1; CYHO01000118.1; CYHO01000119.1; CYHO01000120.1; CYHO01000121.1; CYHO01000122.1; CYHO01000125.1; CYHO01000126.1; CYHO01000127.1; CYHO01000128.1; CYHO01000129.1; CYHO01000130.1; CYHO01000132.1; CYHO01000133.1; CYHO01000134.1; CYHO01000135.1; CYHO01000136.1; CYHO01000137.1; CYHO01000138.1; CYHO01000139.1; CYHO01000140.1; CYHO01000141.1; CYHO01000143.1; CYHO01000145.1; CYHO01000147.1; CYHO01000148.1; CYHO01000149.1; CYHO01000150.1; CYHO01000152.1; CYHO01000155.1; CYHO01000156.1; CYHO01000157.1; CYHO01000160.1; CYHO01000161.1; CYHO01000164.1; CYHO01000165.1; CYHO01000166.1; CYHO01000168.1; CYHO01000170.1; CYHO01000172.1; CYHO01000174.1; CYHO01000175.1; CYHO01000176.1; CYHO01000177.1; CYHO01000178.1; CYHO01000180.1; CYHO01000181.1; CYHO01000182.1; CYHO01000183.1; CYHO01000184.1; CYHO01000187.1; CYHO01000188.1; CYHO01000189.1; CYHO01000190.1; CYHO01000192.1; CYHO01000195.1; CYHO01000196.1; CYHO01000197.1; CYHO01000198.1; CYHO01000199.1; CYHO01000200.1; CYHO01000201.1; CYHO01000202.1; CYHO01000206.1; CYHO01000208.1; CYHO01000209.1; CYHO01000210.1; CYHO01000211.1

Compact view

CYHO01000014.1 - Region 1 - terpene

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Location: 19,808 - 38,212 nt. (total: 18,405 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

CYHO01000017.1 - Region 1 - NRPS,betalactone,transAT-PKS

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Location: 1 - 55,585 nt. (total: 55,585 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))
betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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resistance

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Gene details

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 55585:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal - asn) + (D-tyr - D-asn - gln - pro) + (D-ser - asn)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg16_1

PKS_AT (6..293): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%; inactive: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 85.1
inactive: 46.5
Methoxymalonyl-CoA: 28.9
Methylmalonyl-CoA: 13.8
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg16_2

Search NORINE for peptide: strict or relaxed

CAL_domain (36..479): pk

minowa: fatty_acid

Prediction, score:

fatty_acid: 617.1
NH2: 15.6
shikimic_acid: 0.0
Acetyl-CoA: 0.0
AHBA: 0.0

AMP-binding (2945..3342): asn

NRPSPredictor2: asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 100% (strong)

ctg16_3

Search NORINE for peptide: strict or relaxed

AMP-binding (268..662): tyr

NRPSPredictor2: tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: tyr, bht
Single AA prediction:: tyr

Stachelhaus prediction details:

Stachelhaus sequence:: DALSVGEVVK
Nearest Stachelhaus code:: tyr
Stachelhaus code match:: 100% (strong)

AMP-binding (1778..2173): asn

NRPSPredictor2: asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 100% (strong)

AMP-binding (3289..3694): gln

NRPSPredictor2: gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAQDLGVVDK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 100% (strong)

AMP-binding (4338..4734): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFIAHVVK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 100% (strong)

ctg16_4

Search NORINE for peptide: strict or relaxed

AMP-binding (268..673): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLIDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

AMP-binding (1788..2183): asn

NRPSPredictor2: asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 100% (strong)

ctg16_9

Search NORINE for peptide: strict or relaxed

AMP-binding (13..445): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: N/A
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: gclhIAApvK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 40% (weak)

CYHO01000023.1 - Region 1 - transAT-PKS-like

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Location: 1 - 33,351 nt. (total: 33,351 nt) Show pHMM detection rules used

Region on contig edge.

transAT-PKS-like: cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS) and not PKS_AT)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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KnownClusterBlast

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 33351:

Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account

Polymer prediction:: (ccmal - mal) + (ccmal - ccmal) + (ccmal - mal - ccmal) + (ccmal - ccmal)
Non-colinear ordering:: ctg22_2 + ctg22_5 + ctg22_3 + ctg22_4

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

CYHO01000032.1 - Region 1 - NRPS

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Location: 4,931 - 52,070 nt. (total: 47,140 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 4930 - 52070:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly - thr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg31_27

Search NORINE for peptide: strict or relaxed

AMP-binding (463..861): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGLIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

AMP-binding (1519..1935): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

ctg31_29

Search NORINE for peptide: strict or relaxed

AMP-binding (31..435): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: PLPAQGVVNK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 100% (strong)

CYHO01000035.1 - Region 1 - T3PKS

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Location: 1 - 26,647 nt. (total: 26,647 nt) Show pHMM detection rules used

Region on contig edge.

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

CYHO01000040.1 - Region 1 - NRPS

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Location: 73,992 - 101,634 nt. (total: 27,643 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 73991 - 101634:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (glu - leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg38_91

Search NORINE for peptide: strict or relaxed

AMP-binding (466..867): glu

NRPSPredictor2: glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAKDLGVVDK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 100% (strong)

AMP-binding (1510..1908): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAFMMGMVFK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

CYHO01000047.1 - Region 1 - CDPS

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Location: 34,125 - 54,871 nt. (total: 20,747 nt) Show pHMM detection rules used

CDPS: (CDPS or cycdipepsynth)

Legend:

core biosynthetic genes

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regulatory genes

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resistance

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KnownClusterBlast

Similar known gene clusters

No matches found.

CYHO01000063.1 - Region 1 - other

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Location: 1 - 17,204 nt. (total: 17,204 nt) Show pHMM detection rules used

Region on contig edge.

other: (LmbU or Neocarzinostat or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin or orf2_PTase)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

CYHO01000068.1 - Region 1 - sactipeptide

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Location: 24,188 - 43,648 nt. (total: 19,461 nt) Show pHMM detection rules used

Region on contig edge.

sactipeptide: (subtilosin or thuricin or TIGR04404 or Subtilosin_A or skfc)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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resistance

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KnownClusterBlast

Sactipeptides

Similar known gene clusters

Sactipeptide predictions

Putative Sactipeptide(s)

ctg65_32 leader / core peptide: MKKAVIVENK - GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

Sactipeptides

Core peptide predictions

ctg65_32: Putative sactipeptide; RODEO score: 31.0; Core sequence, approximate: GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

CYHO01000081.1 - Region 1 - NRPS,PKS-like,T3PKS,transAT-PKS

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Location: 282 - 80,495 nt. (total: 80,214 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)
PKS-like: (t2pks2 or ksIII)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 281 - 80495:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly - ccmal - ohmal - mal) + (ccmal - mal - ohmal - mal - mal) + (ccmal - ohmal - mal - mal) + (X - ccmal - ccmal - ccmal) + (mal - mal - ccmal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 8638 - 80495:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly - ccmal - ohmal - mal) + (ccmal - mal - ohmal - mal - mal) + (ccmal - ohmal - mal - mal) + (X - ccmal - ccmal - ccmal) + (mal - mal - ccmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg78_6

Search NORINE for peptide: strict or relaxed

AMP-binding (498..906): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVsnmAiIYK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 60% (weak)

ctg78_9

Search NORINE for peptide: strict or relaxed

CAL_domain (60..476): pk

minowa: fatty_acid

Prediction, score:

fatty_acid: 19.8
NH2: 10.4
shikimic_acid: 0.0
Acetyl-CoA: 0.0
AHBA: 0.0

AMP-binding (1159..1554): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGMIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

ctg78_15

PKS_AT (4..284): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 66.7%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 85.0
inactive: 40.8
Methoxymalonyl-CoA: 27.0
Methylmalonyl-CoA: 15.3
Propionyl-CoA: 11.0
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg78_16

PKS_AT (7..295): pk

ATSignature: (unknown)

No matches above 50%

minowa: inactive

Prediction, score:

inactive: 32.1
Malonyl-CoA: 25.1
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg78_17

PKS_AT (4..283): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 102.4
Methoxymalonyl-CoA: 50.8
inactive: 41.9
Methylmalonyl-CoA: 37.6
Propionyl-CoA: 23.8
2-Methylbutyryl-CoA: 12.8
Ethylmalonyl-CoA: 12.7
Isobutyryl-CoA: 10.7
CHC-CoA: 10.4
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

CYHO01000111.1 - Region 1 - epipeptide

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Location: 1 - 15,407 nt. (total: 15,407 nt) Show pHMM detection rules used

Region on contig edge.

epipeptide: (TIGR04078 and yydH)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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KnownClusterBlast

Similar known gene clusters

CYHO01000124.1 - Region 1 - NRPS

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Location: 1 - 9,121 nt. (total: 9,121 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 9121:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (val - asp)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg120_1

Search NORINE for peptide: strict or relaxed

AMP-binding (470..864): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAFWIGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 100% (strong)

AMP-binding (1501..1904): asp

NRPSPredictor2: asp

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asp

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKVGHIGK
Nearest Stachelhaus code:: asp
Stachelhaus code match:: 100% (strong)

CYHO01000158.1 - Region 1 - NRPS

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Location: 1 - 21,686 nt. (total: 21,686 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 21686:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg147_5

Search NORINE for peptide: strict or relaxed

AMP-binding (311..709): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGCVFK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

CYHO01000169.1 - Region 1 - terpene

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Location: 1 - 5,946 nt. (total: 5,946 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

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resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

CYHO01000179.1 - Region 1 - transAT-PKS-like

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Location: 1 - 7,058 nt. (total: 7,058 nt) Show pHMM detection rules used

Region on contig edge.

transAT-PKS-like: cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS) and not PKS_AT)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 7058:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ohmal) + (ohmal - mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions