# emapper version: emapper-2.0.1b-2-g816e190 emapper DB: 2.0
# command: ./emapper.py  -i Bifidobacterium_bifidum/1.contigAnn/FFN/A00000030.ffn --translate --temp_dir Bifidobacterium_bifidum/4.eggNOG_mapper --output_dir Bifidobacterium_bifidum/4.eggNOG_mapper --output A00000030 --cpu 36 --keep_mapping_files -m diamond
# time: Tue May 31 18:00:00 2022
#query_name	seed_eggNOG_ortholog	seed_ortholog_evalue	seed_ortholog_score	best_tax_level	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	taxonomic scope	eggNOG OGs	best eggNOG OG	COG Functional cat.	eggNOG free text desc.
NIOIMGPL_00002	398513.BBNG_01793	2.3e-259	901.0	Bifidobacteriales	gdhA		1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100		R00248	RC00006,RC02799	ko00000,ko00001,ko01000				Bacteria	2GKXG@201174,4CYTN@85004,COG0334@1,COG0334@2	NA|NA|NA	E	Belongs to the Glu Leu Phe Val dehydrogenases family
NIOIMGPL_00003	398513.BBNG_01794	8.1e-123	446.4	Bifidobacteriales	gntR			ko:K19776					ko00000,ko03000				Bacteria	2GKBM@201174,4CYZS@85004,COG2186@1,COG2186@2	NA|NA|NA	K	FCD
NIOIMGPL_00004	398513.BBNG_01795	2.4e-48	198.4	Bifidobacteriales	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066		ko:K03282					ko00000,ko02000	1.A.22.1			Bacteria	2IQDN@201174,4D13A@85004,COG1970@1,COG1970@2	NA|NA|NA	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NIOIMGPL_00005	702459.BBPR_0025	0.0	2072.4	Bifidobacteriales			3.2.1.55	ko:K01209	ko00520,map00520		R01762		ko00000,ko00001,ko01000		GH51		Bacteria	2GMAK@201174,4CYXS@85004,COG2931@1,COG2931@2,COG3534@1,COG3534@2,COG4932@1,COG4932@2	NA|NA|NA	G	arabinose metabolic process
NIOIMGPL_00008	702459.BBPR_0026	0.0	1544.3	Bifidobacteriales													Bacteria	2HZCI@201174,4CZS1@85004,COG3525@1,COG3525@2	NA|NA|NA	G	Glycosyl hydrolase family 20, domain 2
NIOIMGPL_00009	702459.BBPR_0029	2.2e-188	664.8	Bifidobacteriales				ko:K02529					ko00000,ko03000				Bacteria	2GJRG@201174,4CZ05@85004,COG1609@1,COG1609@2	NA|NA|NA	K	helix_turn _helix lactose operon repressor
NIOIMGPL_00010	702459.BBPR_0030	7.3e-77	293.1	Bifidobacteriales	ulaC		2.7.1.194,2.7.1.197,2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02798,ko:K02821	ko00051,ko00053,ko01100,ko01120,ko02060,map00051,map00053,map01100,map01120,map02060	M00273,M00274,M00283,M00550	R02704,R03232,R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5,4.A.7.1			Bacteria	2I8CH@201174,4D0XI@85004,COG1762@1,COG1762@2	NA|NA|NA	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIOIMGPL_00011	702459.BBPR_0031	3.3e-40	170.6	Bifidobacteriales	ulaC		2.7.1.194	ko:K02821,ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.7.1			Bacteria	2GUM3@201174,4D1AA@85004,COG3414@1,COG3414@2	NA|NA|NA	G	PTS system, Lactose/Cellobiose specific IIB subunit
NIOIMGPL_00012	702459.BBPR_0032	1.6e-261	908.3	Bifidobacteriales	ulaA		2.7.1.194	ko:K02822,ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.7.1			Bacteria	2GMYV@201174,4D064@85004,COG3037@1,COG3037@2	NA|NA|NA	S	PTS system sugar-specific permease component
NIOIMGPL_00013	398513.BBNG_01801	3.5e-137	494.2	Bifidobacteriales				ko:K07043					ko00000				Bacteria	2GMP6@201174,4CZF9@85004,COG1451@1,COG1451@2	NA|NA|NA	S	Protein of unknown function DUF45
NIOIMGPL_00014	398513.BBNG_01802	1.9e-83	315.1	Bifidobacteriales	dps	GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464		ko:K04047					ko00000,ko03036				Bacteria	2IFDP@201174,4CZV3@85004,COG0783@1,COG0783@2	NA|NA|NA	P	Belongs to the Dps family
NIOIMGPL_00015	702459.BBPR_0035	5.8e-189	666.8	Bifidobacteriales	yddG	GO:0003333,GO:0003674,GO:0005215,GO:0005302,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015179,GO:0015192,GO:0015196,GO:0015238,GO:0015318,GO:0015711,GO:0015801,GO:0015807,GO:0015823,GO:0015827,GO:0015828,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039										iBWG_1329.BWG_1294,iE2348C_1286.E2348C_1607,iECDH10B_1368.ECDH10B_1604,iECDH1ME8569_1439.ECDH1ME8569_1416,iECS88_1305.ECS88_1565,iEcDH1_1363.EcDH1_2175,iJO1366.b1473,iNRG857_1313.NRG857_07295,iSSON_1240.SSON_1651,iUMN146_1321.UM146_09675	Bacteria	2GM6M@201174,4CZPP@85004,COG0697@1,COG0697@2	NA|NA|NA	EG	EamA-like transporter family
NIOIMGPL_00016	398513.BBNG_01804	1.2e-241	842.0	Bifidobacteriales	ytfL	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K03699					ko00000,ko02042				Bacteria	2GKN5@201174,4CZKA@85004,COG1253@1,COG1253@2	NA|NA|NA	P	Transporter associated domain
NIOIMGPL_00017	398513.BBNG_01805	7.2e-95	353.2	Bifidobacteriales				ko:K02529					ko00000,ko03000				Bacteria	2GM7M@201174,4D2RZ@85004,COG1609@1,COG1609@2	NA|NA|NA	K	helix_turn _helix lactose operon repressor
NIOIMGPL_00018	398513.BBNG_01806	2.2e-117	428.3	Bifidobacteriales	cah	GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008270,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944	4.2.1.1	ko:K01673	ko00910,map00910		R00132,R10092	RC02807	ko00000,ko00001,ko01000				Bacteria	2GT5H@201174,4D06V@85004,COG0288@1,COG0288@2	NA|NA|NA	P	Reversible hydration of carbon dioxide
NIOIMGPL_00019	398513.BBNG_01807	2.9e-107	394.4	Bifidobacteriales	ahpC		1.11.1.15	ko:K03386	ko04214,map04214				ko00000,ko00001,ko01000,ko04147				Bacteria	2GM74@201174,4CZXS@85004,COG0450@1,COG0450@2	NA|NA|NA	O	C-terminal domain of 1-Cys peroxiredoxin
NIOIMGPL_00020	702459.BBPR_0040	0.0	1161.0	Bifidobacteriales	trxB1		1.8.1.9	ko:K00384	ko00450,map00450		R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000				Bacteria	2GKD2@201174,4CZ6G@85004,COG0492@1,COG0492@2,COG3634@1,COG3634@2	NA|NA|NA	C	Thioredoxin domain
NIOIMGPL_00021	398513.BBNG_01810	4.2e-147	527.3	Bifidobacteriales	yhjX			ko:K08177					ko00000,ko02000	2.A.1.11			Bacteria	2I2ID@201174,4CZX9@85004,COG0477@1,COG2814@2	NA|NA|NA	EGP	Major facilitator Superfamily
NIOIMGPL_00022	398513.BBNG_01810	1e-81	309.3	Bifidobacteriales	yhjX			ko:K08177					ko00000,ko02000	2.A.1.11			Bacteria	2I2ID@201174,4CZX9@85004,COG0477@1,COG2814@2	NA|NA|NA	EGP	Major facilitator Superfamily
NIOIMGPL_00023	398513.BBNG_01811	0.0	1813.1	Bifidobacteriales	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000			iJN678.ppc	Bacteria	2GKDB@201174,4CZS0@85004,COG2352@1,COG2352@2	NA|NA|NA	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NIOIMGPL_00024	702459.BBPR_0043	0.0	1228.0	Bifidobacteriales	yjjP												Bacteria	2HZ8C@201174,4CYR2@85004,COG2966@1,COG2966@2,COG3610@1,COG3610@2	NA|NA|NA	S	Threonine/Serine exporter, ThrE
NIOIMGPL_00025	398513.BBNG_01814	6.5e-180	636.7	Bifidobacteriales													Bacteria	2GJVW@201174,4CZQ4@85004,COG1574@1,COG1574@2	NA|NA|NA	S	Amidohydrolase family
NIOIMGPL_00026	702459.BBPR_0045	1.1e-194	685.6	Bifidobacteriales	gmk		1.1.1.23,2.7.4.8	ko:K00013,ko:K00942	ko00230,ko00340,ko01100,ko01110,ko01230,map00230,map00340,map01100,map01110,map01230	M00026,M00050	R00332,R01158,R01163,R02090,R03012	RC00002,RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000				Bacteria	2GN40@201174,4CZPZ@85004,COG2852@1,COG2852@2	NA|NA|NA	S	Protein conserved in bacteria
NIOIMGPL_00027	398513.BBNG_01816	9.4e-203	712.6	Bifidobacteriales	trpS	GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	2GJ9A@201174,4CYXM@85004,COG0180@1,COG0180@2	NA|NA|NA	J	Belongs to the class-I aminoacyl-tRNA synthetase family
NIOIMGPL_00028	398513.BBNG_01817	6.2e-45	186.8	Bifidobacteriales													Bacteria	2EGRW@1,2HZNH@201174,32FNP@2,4D120@85004	NA|NA|NA	S	Protein of unknown function (DUF3073)
NIOIMGPL_00029	702459.BBPR_0049	1.5e-79	302.4	Bacteria													Bacteria	COG3290@1,COG3290@2	NA|NA|NA	T	protein histidine kinase activity
NIOIMGPL_00030	398513.BBNG_01821	1e-203	715.7	Bifidobacteriales	rfbB	GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000			iNJ661.Rv3464	Bacteria	2GNDU@201174,4CZZY@85004,COG1088@1,COG1088@2	NA|NA|NA	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NIOIMGPL_00031	398513.BBNG_01822	3.5e-29	133.7	Bifidobacteriales													Bacteria	2H65A@201174,4D2BH@85004,COG1835@1,COG1835@2	NA|NA|NA	I	transferase activity, transferring acyl groups other than amino-acyl groups
NIOIMGPL_00032	702459.BBPR_1740	0.0	2440.6	Bifidobacteriales	vpr	GO:0005575,GO:0005576		ko:K14647	ko02024,map02024				ko00000,ko00001,ko01000,ko01002,ko03110				Bacteria	2GK3D@201174,4CZV6@85004,COG1196@1,COG1196@2,COG1404@1,COG1404@2	NA|NA|NA	M	PA domain
NIOIMGPL_00033	702459.BBPR_1741	4.7e-123	447.6	Bifidobacteriales	yplQ			ko:K11068					ko00000,ko02042				Bacteria	2HRAC@201174,4D0D6@85004,COG1272@1,COG1272@2	NA|NA|NA	S	Haemolysin-III related
NIOIMGPL_00034	398513.BBNG_01365	2.4e-233	814.3	Bifidobacteriales	glf	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0071554,GO:0071766,GO:0071840,GO:0071944,GO:0097159,GO:1901265,GO:1901363	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520		R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000			iNJ661.Rv3809c	Bacteria	2GK2Z@201174,4CZ2W@85004,COG0562@1,COG0562@2	NA|NA|NA	M	UDP-galactopyranose mutase
NIOIMGPL_00035	398513.BBNG_01364	0.0	1248.8	Bifidobacteriales	mrcB		2.4.1.129,3.4.16.4	ko:K05365,ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501		R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011		GT51		Bacteria	2GK21@201174,4CZQZ@85004,COG0744@1,COG0744@2	NA|NA|NA	M	Transglycosylase
NIOIMGPL_00036	398513.BBNG_01363	0.0	1270.8	Bifidobacteriales	leuA	GO:0000287,GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0030145,GO:0030955,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0046912,GO:0046914,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	2GISX@201174,4CZYW@85004,COG0119@1,COG0119@2	NA|NA|NA	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NIOIMGPL_00037	398513.BBNG_01362	5.1e-278	963.0	Bifidobacteriales													Bacteria	2GNKK@201174,4CZMC@85004,COG1409@1,COG1409@2	NA|NA|NA	S	Calcineurin-like phosphoesterase
NIOIMGPL_00038	398513.BBNG_01360	4.5e-285	986.9	Bifidobacteriales	pbpB		2.7.11.1,3.4.16.4	ko:K03587,ko:K08384,ko:K08724,ko:K08884,ko:K12132	ko00550,ko01501,map00550,map01501				ko00000,ko00001,ko01000,ko01001,ko01011,ko03036				Bacteria	2IAHD@201174,4D094@85004,COG2815@1,COG2815@2	NA|NA|NA	S	PASTA domain
NIOIMGPL_00039	398513.BBNG_01359	1.7e-116	425.2	Bifidobacteriales													Bacteria	2C7PT@1,2GM64@201174,2ZXN2@2,4CYPY@85004	NA|NA|NA		
NIOIMGPL_00040	398513.BBNG_01358	1.7e-212	745.0	Bifidobacteriales	asd	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0030312,GO:0036094,GO:0040007,GO:0043891,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071944,GO:0097159,GO:1901265,GO:1901363	1.2.1.11,1.2.1.12	ko:K00133,ko:K00134	ko00010,ko00260,ko00261,ko00270,ko00300,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04066,ko05010,map00010,map00260,map00261,map00270,map00300,map00710,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04066,map05010	M00001,M00002,M00003,M00016,M00017,M00018,M00033,M00165,M00166,M00308,M00525,M00526,M00527,M00552	R01061,R02291	RC00149,RC00684	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147				Bacteria	2GJJ8@201174,4CZPY@85004,COG0136@1,COG0136@2	NA|NA|NA	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NIOIMGPL_00042	702459.BBPR_1750	2.1e-97	361.7	Bifidobacteriales	askB		1.1.1.3,2.7.2.4	ko:K00928,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000				Bacteria	2GN0G@201174,4D00P@85004,COG0527@1,COG0527@2	NA|NA|NA	E	ACT domain
NIOIMGPL_00043	398513.BBNG_01357	1.8e-136	491.9	Bifidobacteriales	ask	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.3,2.7.2.4	ko:K00928,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000				Bacteria	2GN0G@201174,4CYSD@85004,COG0527@1,COG0527@2	NA|NA|NA	E	Amino acid kinase family
NIOIMGPL_00044	398513.BBNG_01356	6.7e-110	403.3	Bifidobacteriales	recR	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576		ko:K06187	ko03440,map03440				ko00000,ko00001,ko03400				Bacteria	2GJY0@201174,4CZRI@85004,COG0353@1,COG0353@2	NA|NA|NA	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NIOIMGPL_00045	702459.BBPR_1753	0.0	1590.5	Bifidobacteriales	dnaX	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0042575,GO:0042802,GO:0043170,GO:0043846,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050790,GO:0061695,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	2GJKA@201174,4CZMY@85004,COG2812@1,COG2812@2	NA|NA|NA	L	DNA polymerase III subunit gamma tau
NIOIMGPL_00046	398513.BBNG_01354	6.4e-215	753.1	Bifidobacteriales	dagK	GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110		R02240	RC00002,RC00017	ko00000,ko00001,ko01000				Bacteria	2GK3P@201174,4CZ1S@85004,COG1597@1,COG1597@2	NA|NA|NA	I	Diacylglycerol kinase catalytic domain protein
NIOIMGPL_00047	398513.BBNG_01353	6.9e-57	226.5	Bifidobacteriales													Bacteria	2DRBM@1,2HZRZ@201174,33B4F@2,4D1G6@85004	NA|NA|NA	S	TIGRFAM helicase secretion neighborhood TadE-like protein
NIOIMGPL_00048	702459.BBPR_1758	1.9e-41	174.9	Bifidobacteriales													Bacteria	2EHCF@1,2GR72@201174,33B4A@2,4D1FR@85004	NA|NA|NA	S	Protein of unknown function (DUF4244)
NIOIMGPL_00049	398513.BBNG_01350	3.2e-15	86.7	Bifidobacteriales	gspF			ko:K12510,ko:K12511					ko00000,ko02044				Bacteria	2I2FP@201174,4D16W@85004,COG2064@1,COG2064@2	NA|NA|NA	NU	Type II secretion system (T2SS), protein F
NIOIMGPL_00050	398513.BBNG_01350	9.2e-14	82.8	Bifidobacteriales	gspF			ko:K12510,ko:K12511					ko00000,ko02044				Bacteria	2I2FP@201174,4D16W@85004,COG2064@1,COG2064@2	NA|NA|NA	NU	Type II secretion system (T2SS), protein F
NIOIMGPL_00051	398513.BBNG_01348	5.1e-122	443.7	Bifidobacteriales				ko:K12510					ko00000,ko02044				Bacteria	2GRXU@201174,4D1A3@85004,COG4965@1,COG4965@2	NA|NA|NA	U	Type ii secretion system
NIOIMGPL_00052	702459.BBPR_1761	2.8e-190	671.0	Bifidobacteriales	cpaF			ko:K02283					ko00000,ko02035,ko02044				Bacteria	2GKKJ@201174,4CZF2@85004,COG4962@1,COG4962@2	NA|NA|NA	U	Type II IV secretion system protein
NIOIMGPL_00053	702459.BBPR_1762	2.6e-152	544.7	Bifidobacteriales	cpaE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464		ko:K04562					ko00000,ko02035				Bacteria	2HZIH@201174,4D0JG@85004,COG0455@1,COG0455@2	NA|NA|NA	D	bacterial-type flagellum organization
NIOIMGPL_00055	398513.BBNG_01345	0.0	1480.7	Bifidobacteriales	ppk		2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018				ko00000,ko00001,ko01000,ko03019				Bacteria	2GJ0B@201174,4CYXH@85004,COG0855@1,COG0855@2	NA|NA|NA	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NIOIMGPL_00056	702459.BBPR_1764	6.3e-201	706.4	Bifidobacteriales	mutT		3.6.1.13,3.6.1.55	ko:K01515,ko:K03574,ko:K08296	ko00230,map00230		R01054	RC00002	ko00000,ko00001,ko01000,ko03400				Bacteria	2GNRV@201174,4CZ90@85004,COG0494@1,COG0494@2,COG2062@1,COG2062@2	NA|NA|NA	LT	Phosphoglycerate mutase family
NIOIMGPL_00057	398513.BBNG_01343	8.6e-91	340.1	Bifidobacteriales													Bacteria	28MMU@1,2HAD5@201174,2ZAXG@2,4CZ1Q@85004	NA|NA|NA		
NIOIMGPL_00058	702459.BBPR_1767	5.7e-29	132.9	Bifidobacteriales	ureD			ko:K03190					ko00000				Bacteria	2HZI9@201174,4D0IT@85004,COG0829@1,COG0829@2	NA|NA|NA	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NIOIMGPL_00059	398513.BBNG_01341	5.9e-131	473.4	Bifidobacteriales													Bacteria	2GMQQ@201174,4CZRJ@85004,COG1216@1,COG1216@2	NA|NA|NA	S	Glycosyltransferase, group 2 family protein
NIOIMGPL_00060	326426.Bbr_1889	0.0	1422.5	Bifidobacteriales													Bacteria	2CBRJ@1,2GKSC@201174,2Z7W0@2,4CZAS@85004	NA|NA|NA	S	LPXTG-motif cell wall anchor domain protein
NIOIMGPL_00061	398513.BBNG_01189	6.7e-152	543.5	Bifidobacteriales													Bacteria	2BIEZ@1,2GSHH@201174,32CMF@2,4D1JU@85004	NA|NA|NA	S	Protein of unknown function (DUF3801)
NIOIMGPL_00062	702459.BBPR_0728	1.4e-166	592.4	Bifidobacteriales													Bacteria	2DNQG@1,2I2FY@201174,32YJZ@2,4CZE9@85004	NA|NA|NA		
NIOIMGPL_00063	702459.BBPR_0727	0.0	1999.9	Bifidobacteriales													Bacteria	2I2FX@201174,4CYVM@85004,COG1216@1,COG1216@2,COG5617@1,COG5617@2	NA|NA|NA	S	Glycosyl transferase, family 2
NIOIMGPL_00064	398513.BBNG_00656	5.8e-54	216.5	Bifidobacteriales	whiB			ko:K18955					ko00000,ko03000				Bacteria	2CC1Y@1,2IQ4Q@201174,32RUK@2,4D12I@85004	NA|NA|NA	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
NIOIMGPL_00065	398513.BBNG_00654	6.6e-268	929.5	Bifidobacteriales													Bacteria	2GJJJ@201174,4CYQY@85004,COG1316@1,COG1316@2	NA|NA|NA	K	Cell envelope-related transcriptional attenuator domain
NIOIMGPL_00066	398513.BBNG_00653	0.0	1183.7	Bifidobacteriales				ko:K03466					ko00000,ko03036	3.A.12			Bacteria	2GJBR@201174,4CYU3@85004,COG1674@1,COG1674@2	NA|NA|NA	D	FtsK/SpoIIIE family
NIOIMGPL_00067	398513.BBNG_00652	5.4e-46	189.9	Bifidobacteriales	whiB	GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141		ko:K18955					ko00000,ko03000				Bacteria	2DMIE@1,2IQCG@201174,32RSG@2,4D11W@85004	NA|NA|NA	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
NIOIMGPL_00068	398513.BBNG_00651	9.5e-286	988.8	Bifidobacteriales	pdtaS	GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K00936		M00839			ko00000,ko00002,ko01000,ko01001,ko02022				Bacteria	2GKMP@201174,4CYV1@85004,COG3920@1,COG3920@2	NA|NA|NA	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NIOIMGPL_00069	398513.BBNG_00650	9.8e-142	509.6	Bifidobacteriales	yplQ			ko:K11068					ko00000,ko02042				Bacteria	2GJGQ@201174,4CZGT@85004,COG1272@1,COG1272@2	NA|NA|NA	S	Haemolysin-III related
NIOIMGPL_00070	702459.BBPR_0720	2.3e-107	394.8	Bifidobacteriales													Bacteria	2AVVF@1,2INFF@201174,31MP8@2,4D167@85004	NA|NA|NA		
NIOIMGPL_00073	398513.BBNG_00649	7.5e-80	303.1	Bifidobacteriales	greA	GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0032774,GO:0032784,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141		ko:K03624					ko00000,ko03021				Bacteria	2GNZV@201174,4D0QM@85004,COG0782@1,COG0782@2	NA|NA|NA	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NIOIMGPL_00074	398513.BBNG_00648	5.7e-73	280.0	Bifidobacteriales	fkbP		5.2.1.8	ko:K01802					ko00000,ko01000				Bacteria	2GJK2@201174,4D0V6@85004,COG0545@1,COG0545@2	NA|NA|NA	G	Peptidyl-prolyl cis-trans
NIOIMGPL_00075	398513.BBNG_00647	8.8e-281	972.2	Bifidobacteriales	sdaA		4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230		R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000				Bacteria	2GJPA@201174,4CZ6I@85004,COG1760@1,COG1760@2	NA|NA|NA	E	Serine dehydratase alpha chain
NIOIMGPL_00076	398513.BBNG_00646	1.6e-97	362.1	Bifidobacteriales													Bacteria	2ASIR@1,2IHD9@201174,31HZA@2,4D0QP@85004	NA|NA|NA		
NIOIMGPL_00078	702459.BBPR_0714	1e-184	652.5	Bifidobacteriales	ppx	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230		R03409	RC00002	ko00000,ko00001,ko01000				Bacteria	2GJBN@201174,4CZCS@85004,COG0248@1,COG0248@2	NA|NA|NA	FP	Ppx/GppA phosphatase family
NIOIMGPL_00079	398513.BBNG_00644	2e-106	391.7	Bifidobacteriales	ppx2		3.6.1.11,3.6.1.40	ko:K01524,ko:K09009	ko00230,map00230		R03409	RC00002	ko00000,ko00001,ko01000				Bacteria	2I8CS@201174,4CZQX@85004,COG1507@1,COG1507@2	NA|NA|NA	S	Protein of unknown function (DUF501)
NIOIMGPL_00080	702459.BBPR_0712	3.2e-101	374.4	Bifidobacteriales	divIC			ko:K05589,ko:K13052					ko00000,ko03036				Bacteria	2IR5G@201174,4D0SS@85004,COG2919@1,COG2919@2	NA|NA|NA	D	Septum formation initiator
NIOIMGPL_00081	398513.BBNG_00642	6.9e-245	852.8	Bifidobacteriales	eno		4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147				Bacteria	2GJAY@201174,4CYT3@85004,COG0148@1,COG0148@2	NA|NA|NA	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NIOIMGPL_00082	398513.BBNG_00641	6.4e-153	546.6	Bacteria	pabC		2.6.1.42,2.6.1.85,4.1.3.38	ko:K00826,ko:K01665,ko:K02619,ko:K03342	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R01716,R02199,R05553,R10991	RC00006,RC00010,RC00036,RC01418,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	COG0115@1,COG0115@2	NA|NA|NA	E	branched-chain-amino-acid transaminase activity
NIOIMGPL_00083	702459.BBPR_0709	9e-297	1025.4	Bifidobacteriales	pabB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.6.1.85,4.1.3.27,4.1.3.38	ko:K01657,ko:K01665,ko:K03342,ko:K13503,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716,R05553	RC00010,RC01418,RC01843,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01007			iEC042_1314.EC042_1977	Bacteria	2GKJT@201174,4D20E@85004,COG0147@1,COG0147@2	NA|NA|NA	EH	chorismate binding enzyme
NIOIMGPL_00084	702459.BBPR_0708	0.0	1844.7	Bifidobacteriales	mfd			ko:K03723	ko03420,map03420				ko00000,ko00001,ko01000,ko03400				Bacteria	2GJ42@201174,4CZ8X@85004,COG1197@1,COG1197@2	NA|NA|NA	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NIOIMGPL_00085	398513.BBNG_00638	4.9e-113	413.7	Bifidobacteriales	pth	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101	3.1.1.29	ko:K01056					ko00000,ko01000,ko03012				Bacteria	2GKCV@201174,4CZBE@85004,COG0193@1,COG0193@2	NA|NA|NA	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NIOIMGPL_00086	398513.BBNG_00637	1.1e-95	355.9	Bifidobacteriales			2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130		R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000				Bacteria	2HZCB@201174,4CZQI@85004,COG1247@1,COG1247@2	NA|NA|NA	M	Acetyltransferase (GNAT) domain
NIOIMGPL_00087	398513.BBNG_00636	4.9e-145	520.4	Bifidobacteriales	tagH	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0015921,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:1901264,GO:1901505	3.6.3.38,3.6.3.40	ko:K09689,ko:K09693	ko02010,map02010	M00249,M00251			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.101,3.A.1.104			Bacteria	2GIVF@201174,4D1YJ@85004,COG1134@1,COG1134@2	NA|NA|NA	GM	ABC transporter
NIOIMGPL_00088	398513.BBNG_00635	2.3e-150	538.1	Bifidobacteriales				ko:K09690,ko:K09692	ko02010,map02010	M00250,M00251			ko00000,ko00001,ko00002,ko02000	3.A.1.103,3.A.1.104			Bacteria	2HZUN@201174,4D1UK@85004,COG1682@1,COG1682@2	NA|NA|NA	GM	ABC-2 type transporter
NIOIMGPL_00089	398513.BBNG_00634	1.9e-197	694.9	Bifidobacteriales													Bacteria	2IH1R@201174,4D0MJ@85004,COG0451@1,COG0451@2	NA|NA|NA	GM	GDP-mannose 4,6 dehydratase
NIOIMGPL_00090	702459.BBPR_0702	1.8e-130	471.9	Bifidobacteriales	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60,4.6.1.12	ko:K00991,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000				Bacteria	2GNHP@201174,4CYVZ@85004,COG1211@1,COG1211@2	NA|NA|NA	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NIOIMGPL_00092	398513.BBNG_00630	1.2e-216	758.8	Bacteria				ko:K13663					ko00000,ko01000				Bacteria	COG1835@1,COG1835@2	NA|NA|NA	I	transferase activity, transferring acyl groups other than amino-acyl groups
NIOIMGPL_00093	702459.BBPR_0699	0.0	1261.9	Bifidobacteriales			2.7.8.14,2.7.8.47	ko:K18704			R11614,R11621		ko00000,ko01000				Bacteria	2I9SV@201174,4D24D@85004,COG1887@1,COG1887@2	NA|NA|NA	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NIOIMGPL_00094	398513.BBNG_00628	2.9e-177	627.9	Bifidobacteriales	tagB		2.7.8.14,2.7.8.44,2.7.8.47	ko:K18704,ko:K21285			R11558,R11614,R11621	RC00078	ko00000,ko01000			iYO844.BSU35760	Bacteria	2GMXY@201174,4D1XX@85004,COG1887@1,COG1887@2	NA|NA|NA	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NIOIMGPL_00095	702459.BBPR_0697	0.0	1950.6	Bifidobacteriales		GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944		ko:K09118					ko00000				Bacteria	2GMP3@201174,4CYW1@85004,COG1615@1,COG1615@2	NA|NA|NA	S	Uncharacterised protein family (UPF0182)
NIOIMGPL_00096	702459.BBPR_0696	7.4e-231	806.2	Bifidobacteriales	ybbD		3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000				Bacteria	2GM43@201174,4CZ6R@85004,COG1472@1,COG1472@2	NA|NA|NA	G	Glycosyl hydrolase family 3 N-terminal domain protein
NIOIMGPL_00097	398513.BBNG_00625	4.5e-197	693.7	Bifidobacteriales													Bacteria	2C746@1,2I2G8@201174,340R4@2,4CZHI@85004	NA|NA|NA		
NIOIMGPL_00098	702459.BBPR_0694	4.3e-152	543.9	Bifidobacteriales	ytrE			ko:K02003,ko:K09810,ko:K10038	ko02010,map02010	M00227,M00255,M00258			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125,3.A.1.3.2			Bacteria	2ICH8@201174,4CZF8@85004,COG1136@1,COG1136@2	NA|NA|NA	V	ATPases associated with a variety of cellular activities
NIOIMGPL_00099	702459.BBPR_0693	2.4e-190	671.4	Bifidobacteriales													Bacteria	2I9EN@201174,4D025@85004,COG3023@1,COG3023@2	NA|NA|NA	V	N-Acetylmuramoyl-L-alanine amidase
NIOIMGPL_00100	398513.BBNG_00622	1.1e-95	355.9	Bifidobacteriales	argE												Bacteria	2GM84@201174,4CYZT@85004,COG0624@1,COG0624@2	NA|NA|NA	E	Peptidase dimerisation domain
NIOIMGPL_00101	398513.BBNG_00622	8.8e-68	263.1	Bifidobacteriales	argE												Bacteria	2GM84@201174,4CYZT@85004,COG0624@1,COG0624@2	NA|NA|NA	E	Peptidase dimerisation domain
NIOIMGPL_00102	398513.BBNG_00621	2.7e-103	381.3	Bifidobacteriales		GO:0008150,GO:0009605,GO:0009607,GO:0020012,GO:0030682,GO:0042783,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136											Bacteria	2AN86@1,2HWWU@201174,31D67@2,4CZZS@85004	NA|NA|NA	S	Protein of unknown function (DUF3043)
NIOIMGPL_00103	398513.BBNG_00620	3.5e-194	684.1	Bifidobacteriales	lpdA		1.16.1.1,1.8.1.4	ko:K00382,ko:K00520	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	2GIXY@201174,4CZEI@85004,COG1249@1,COG1249@2	NA|NA|NA	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NIOIMGPL_00104	702459.BBPR_0689	1.4e-101	375.6	Bifidobacteriales													Bacteria	2AUFS@1,2I87Z@201174,2ZBYU@2,4CYT8@85004	NA|NA|NA	S	Domain of unknown function (DUF4191)
NIOIMGPL_00105	398513.BBNG_00618	3.1e-286	990.3	Bifidobacteriales	glnA	GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727		R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147				Bacteria	2GMN1@201174,4CZNK@85004,COG0174@1,COG0174@2	NA|NA|NA	E	glutamine synthetase
NIOIMGPL_00106	1690.BPSG_0228	4.7e-10	70.1	Bifidobacteriales													Bacteria	2AVGA@1,2IMUF@201174,31M8G@2,4D13I@85004	NA|NA|NA		
NIOIMGPL_00108	640132.Srot_1956	5.5e-33	148.7	Actinobacteria	traSA			ko:K03466					ko00000,ko03036	3.A.12			Bacteria	2GJA3@201174,COG1674@1,COG1674@2	NA|NA|NA	D	DNA segregation ATPase FtsK SpoIIIE
NIOIMGPL_00112	176279.SERP2454	5.2e-79	301.2	Staphylococcaceae													Bacteria	1VC2T@1239,28JU1@1,2Z9J4@2,4GYTJ@90964,4HXY8@91061	NA|NA|NA	S	GIY-YIG catalytic domain
NIOIMGPL_00113	1134912.AJTV01000037_gene2468	7.7e-29	134.0	Proteobacteria			3.1.21.4	ko:K01155					ko00000,ko01000,ko02048				Bacteria	1RCXY@1224,28KNW@1,2ZA74@2	NA|NA|NA	L	Recognizes the double-stranded sequence CTCGAG and cleaves after C-1
NIOIMGPL_00114	58123.JOFJ01000010_gene885	6.3e-115	421.4	Streptosporangiales													Bacteria	2I3XK@201174,4EMGG@85012,COG0827@1,COG0827@2	NA|NA|NA	L	DNA restriction-modification system
NIOIMGPL_00115	398513.BBNG_00607	2e-86	326.2	Bifidobacteriales	int			ko:K14059					ko00000				Bacteria	2GMMI@201174,4D0E4@85004,COG0582@1,COG0582@2	NA|NA|NA	L	Phage integrase, N-terminal SAM-like domain
NIOIMGPL_00116	398513.BBNG_00606	4.4e-160	570.5	Bifidobacteriales	gmk		1.1.1.23,2.7.4.8	ko:K00013,ko:K00942	ko00230,ko00340,ko01100,ko01110,ko01230,map00230,map00340,map01100,map01110,map01230	M00026,M00050	R00332,R01158,R01163,R02090,R03012	RC00002,RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000				Bacteria	2I2HQ@201174,4D00A@85004,COG2852@1,COG2852@2	NA|NA|NA	S	Protein conserved in bacteria
NIOIMGPL_00117	702459.BBPR_0686	1.2e-209	735.7	Bifidobacteriales	mrp	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0040007,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141		ko:K03593					ko00000,ko03029,ko03036				Bacteria	2GJUZ@201174,4CZDC@85004,COG0489@1,COG0489@2	NA|NA|NA	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NIOIMGPL_00118	398513.BBNG_00604	5.5e-30	136.3	Bifidobacteriales	ligA	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430		R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400				Bacteria	2GJUY@201174,4CZBC@85004,COG0272@1,COG0272@2	NA|NA|NA	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NIOIMGPL_00119	398513.BBNG_00604	0.0	1601.3	Bifidobacteriales	ligA	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430		R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400				Bacteria	2GJUY@201174,4CZBC@85004,COG0272@1,COG0272@2	NA|NA|NA	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NIOIMGPL_00120	398513.BBNG_00603	0.0	2066.2	Bifidobacteriales													Bacteria	2GWSR@201174,4CZ33@85004,COG0457@1,COG0457@2	NA|NA|NA	S	Tetratricopeptide repeat
NIOIMGPL_00121	702459.BBPR_0683	0.0	1412.5	Bifidobacteriales													Bacteria	2GNXR@201174,4CZXK@85004,COG1807@1,COG1807@2	NA|NA|NA	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NIOIMGPL_00122	398513.BBNG_00601	4.9e-75	287.0	Bifidobacteriales			2.8.2.22	ko:K01023					ko00000,ko01000				Bacteria	2A5FI@1,2I8X3@201174,30U5H@2,4D09F@85004	NA|NA|NA	S	Arylsulfotransferase Ig-like domain
NIOIMGPL_00123	702459.BBPR_0681	4.9e-137	493.8	Bifidobacteriales	bioM			ko:K16784,ko:K16786	ko02010,map02010	M00581,M00582			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35			Bacteria	2I9PF@201174,4D04S@85004,COG1122@1,COG1122@2	NA|NA|NA	P	ATPases associated with a variety of cellular activities
NIOIMGPL_00124	398513.BBNG_00599	7.8e-213	746.1	Bifidobacteriales													Bacteria	2GNMB@201174,4CZ48@85004,COG0436@1,COG0436@2	NA|NA|NA	E	Aminotransferase class I and II
NIOIMGPL_00125	702459.BBPR_0679	1.7e-139	501.9	Bifidobacteriales	ppgK		2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	2GJA0@201174,4CYR1@85004,COG1940@1,COG1940@2	NA|NA|NA	GK	ROK family
NIOIMGPL_00127	398513.BBNG_00596	1.1e-104	386.0	Bifidobacteriales	ribU	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656											Bacteria	2IAX0@201174,4CZQD@85004,COG3601@1,COG3601@2	NA|NA|NA	U	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NIOIMGPL_00128	702459.BBPR_0676	1.7e-14	84.0	Bifidobacteriales	ecfA			ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35			Bacteria	2I2G4@201174,4CZJE@85004,COG0619@1,COG0619@2,COG1129@1,COG1129@2	NA|NA|NA	GP	ABC transporter, ATP-binding protein
NIOIMGPL_00129	702459.BBPR_0676	1.8e-40	171.8	Bifidobacteriales	ecfA			ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35			Bacteria	2I2G4@201174,4CZJE@85004,COG0619@1,COG0619@2,COG1129@1,COG1129@2	NA|NA|NA	GP	ABC transporter, ATP-binding protein
NIOIMGPL_00130	398513.BBNG_00595	0.0	1129.8	Bifidobacteriales	ecfA			ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35			Bacteria	2I2G4@201174,4CZJE@85004,COG0619@1,COG0619@2,COG1129@1,COG1129@2	NA|NA|NA	GP	ABC transporter, ATP-binding protein
NIOIMGPL_00131	398513.BBNG_00594	5.2e-257	893.3	Bifidobacteriales				ko:K18926		M00715			ko00000,ko00002,ko02000	2.A.1.3.30			Bacteria	2GIZX@201174,4CZ0R@85004,COG0477@1,COG2814@2	NA|NA|NA	EGP	Major facilitator Superfamily
NIOIMGPL_00133	702459.BBPR_0674	2.2e-174	618.2	Bifidobacteriales	rarA			ko:K07478					ko00000				Bacteria	2GKDP@201174,4CZ2K@85004,COG2256@1,COG2256@2	NA|NA|NA	L	Recombination factor protein RarA
NIOIMGPL_00134	398513.BBNG_00593	4.1e-27	127.1	Bifidobacteriales	rarA			ko:K07478					ko00000				Bacteria	2GKDP@201174,4CZ2K@85004,COG2256@1,COG2256@2	NA|NA|NA	L	Recombination factor protein RarA
NIOIMGPL_00135	398513.BBNG_00592	0.0	1691.0	Bifidobacteriales													Bacteria	2GJSV@201174,4CZVX@85004,COG4581@1,COG4581@2	NA|NA|NA	L	DEAD DEAH box helicase
NIOIMGPL_00136	702459.BBPR_0672	1.9e-192	678.3	Bifidobacteriales			2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018				ko00000,ko00001,ko01000,ko03019				Bacteria	2GKRN@201174,4CZZU@85004,COG2326@1,COG2326@2	NA|NA|NA	S	Polyphosphate kinase 2 (PPK2)
NIOIMGPL_00137	702459.BBPR_0671	2.3e-78	298.1	Bifidobacteriales	gluD			ko:K02029,ko:K10007	ko02010,map02010	M00233,M00236			ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.9			Bacteria	2GNBH@201174,4CZB4@85004,COG0765@1,COG0765@2	NA|NA|NA	E	Binding-protein-dependent transport system inner membrane component
NIOIMGPL_00138	702459.BBPR_0670	6.8e-111	406.8	Bifidobacteriales	gluC	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039		ko:K10006,ko:K10040	ko02010,map02010	M00228,M00233			ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.9			Bacteria	2GNUR@201174,4CZ5M@85004,COG0765@1,COG0765@2	NA|NA|NA	E	Binding-protein-dependent transport system inner membrane component
NIOIMGPL_00139	702459.BBPR_0669	9.5e-147	526.2	Bifidobacteriales	gluB			ko:K10005	ko02010,map02010	M00233			ko00000,ko00001,ko00002,ko02000	3.A.1.3.9			Bacteria	2GJH8@201174,4CZA4@85004,COG0834@1,COG0834@2	NA|NA|NA	ET	Belongs to the bacterial solute-binding protein 3 family
NIOIMGPL_00140	398513.BBNG_00587	1.5e-144	518.8	Bifidobacteriales	gluA		3.6.3.21	ko:K02028,ko:K10008	ko02010,map02010	M00233,M00236			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.9			Bacteria	2GIZW@201174,4CYXE@85004,COG1126@1,COG1126@2	NA|NA|NA	E	ATP-binding protein of ABC transporter for glutamate K02028
NIOIMGPL_00141	702459.BBPR_0667	4.9e-84	317.0	Bifidobacteriales				ko:K03976,ko:K19055					ko00000,ko01000,ko03016				Bacteria	2GKUX@201174,4D0MH@85004,COG2606@1,COG2606@2	NA|NA|NA	S	Aminoacyl-tRNA editing domain
NIOIMGPL_00142	702459.BBPR_0666	5.3e-84	317.0	Bifidobacteriales													Bacteria	2ISMU@201174,4D1AF@85004,COG2197@1,COG2197@2	NA|NA|NA	K	helix_turn_helix, Lux Regulon
NIOIMGPL_00143	702459.BBPR_0665	0.0	1203.7	Bifidobacteriales	aspS	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029				Bacteria	2GJHU@201174,4CYWQ@85004,COG0173@1,COG0173@2	NA|NA|NA	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NIOIMGPL_00144	398513.BBNG_00581	2.7e-263	914.1	Bifidobacteriales	hisS		6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	2GIYJ@201174,4CYR9@85004,COG0124@1,COG0124@2	NA|NA|NA	J	Histidyl-tRNA synthetase
NIOIMGPL_00145	398513.BBNG_00580	6.6e-217	760.0	Bifidobacteriales			3.1.26.12,3.2.1.8	ko:K01181,ko:K08300,ko:K08301	ko03018,map03018	M00394			ko00000,ko00001,ko00002,ko01000,ko03009,ko03019				Bacteria	2I2EC@201174,4CYYM@85004,COG3266@1,COG3266@2	NA|NA|NA	S	Domain of Unknown Function (DUF349)
NIOIMGPL_00149	398513.BBNG_00576	0.0	1591.2	Bifidobacteriales	clpC			ko:K03696	ko01100,map01100				ko00000,ko03110				Bacteria	2GJ77@201174,4CZCH@85004,COG0542@1,COG0542@2	NA|NA|NA	O	ATPase family associated with various cellular activities (AAA)
NIOIMGPL_00150	702459.BBPR_0657	3e-184	651.0	Bifidobacteriales	uspA												Bacteria	2IA7S@201174,4CZZ0@85004,COG0589@1,COG0589@2	NA|NA|NA	T	Belongs to the universal stress protein A family
NIOIMGPL_00151	702459.BBPR_0656	1.1e-192	679.1	Bifidobacteriales													Bacteria	28NWB@1,2GJ74@201174,2ZBU7@2,4CYW9@85004	NA|NA|NA	S	Protein of unknown function (DUF3027)
NIOIMGPL_00152	398513.BBNG_00573	1e-66	259.2	Bifidobacteriales	cspB			ko:K03704					ko00000,ko03000				Bacteria	2IKXN@201174,4D0V4@85004,COG1278@1,COG1278@2	NA|NA|NA	K	'Cold-shock' DNA-binding domain
NIOIMGPL_00153	398513.BBNG_00572	2.9e-238	830.9	Bifidobacteriales			2.7.13.3	ko:K02484,ko:K07653,ko:K07768	ko02020,map02020	M00443,M00460			ko00000,ko00001,ko00002,ko01000,ko01001,ko02022				Bacteria	2I2DU@201174,4CZNF@85004,COG3850@1,COG3850@2,COG5002@1,COG5002@2	NA|NA|NA	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NIOIMGPL_00154	398513.BBNG_00571	1.4e-133	482.3	Bifidobacteriales													Bacteria	2GIZB@201174,4CYPS@85004,COG0745@1,COG0745@2	NA|NA|NA	KT	Response regulator receiver domain protein
NIOIMGPL_00155	702459.BBPR_0652	2.8e-173	614.8	Bifidobacteriales													Bacteria	2B59T@1,2HZNR@201174,31Y3Y@2,4D12Q@85004	NA|NA|NA		
NIOIMGPL_00156	398513.BBNG_00569	1.7e-10	72.0	Bifidobacteriales													Bacteria	2GQI8@201174,4D17K@85004,COG4842@1,COG4842@2	NA|NA|NA	S	Proteins of 100 residues with WXG
NIOIMGPL_00157	398513.BBNG_00568	2.3e-290	1004.2	Bifidobacteriales	groL	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016020,GO:0016465,GO:0022610,GO:0030112,GO:0030312,GO:0030313,GO:0031975,GO:0032991,GO:0036293,GO:0040007,GO:0042026,GO:0042603,GO:0043388,GO:0044093,GO:0044183,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051704,GO:0061077,GO:0065007,GO:0065009,GO:0070482,GO:0071944,GO:0101031,GO:1990220,GO:2000677,GO:2000679		ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152				ko00000,ko00001,ko03019,ko03029,ko03110,ko04147				Bacteria	2GKC9@201174,4CZJK@85004,COG0459@1,COG0459@2	NA|NA|NA	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NIOIMGPL_00158	398513.BBNG_00566	2.2e-44	184.5	Bifidobacteriales	cspA			ko:K03704					ko00000,ko03000				Bacteria	2GQRU@201174,4D1FB@85004,COG1278@1,COG1278@2	NA|NA|NA	K	'Cold-shock' DNA-binding domain
NIOIMGPL_00159	398513.BBNG_00565	3.4e-71	275.0	Bifidobacteriales													Bacteria	2DP6P@1,2GQYA@201174,330SA@2,4CZYT@85004	NA|NA|NA	S	LytR cell envelope-related transcriptional attenuator
NIOIMGPL_00160	702459.BBPR_0647	8e-145	519.6	Bifidobacteriales	ung	GO:0003674,GO:0003824,GO:0004844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340				ko00000,ko00001,ko01000,ko03400				Bacteria	2GJ9Z@201174,4CZ3Y@85004,COG0692@1,COG0692@2	NA|NA|NA	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NIOIMGPL_00161	702459.BBPR_0646	1e-196	692.6	Bifidobacteriales	moxR			ko:K03924					ko00000,ko01000				Bacteria	2GK07@201174,4CZ2I@85004,COG0714@1,COG0714@2	NA|NA|NA	S	ATPase family associated with various cellular activities (AAA)
NIOIMGPL_00162	398513.BBNG_00562	8.6e-138	497.3	Bifidobacteriales													Bacteria	2GKSJ@201174,4CYYD@85004,COG1721@1,COG1721@2	NA|NA|NA	S	Protein of unknown function DUF58
NIOIMGPL_00163	398513.BBNG_00560	1.3e-140	505.8	Bifidobacteriales				ko:K07114					ko00000,ko02000	1.A.13.2.2,1.A.13.2.3			Bacteria	2I9VM@201174,4CZ00@85004,COG2304@1,COG2304@2	NA|NA|NA	S	von Willebrand factor (vWF) type A domain
NIOIMGPL_00164	398513.BBNG_00559	3.6e-148	531.2	Bifidobacteriales				ko:K07114					ko00000,ko02000	1.A.13.2.2,1.A.13.2.3			Bacteria	2GJMP@201174,4CZ8P@85004,COG2304@1,COG2304@2	NA|NA|NA	S	von Willebrand factor (vWF) type A domain
NIOIMGPL_00165	702459.BBPR_0641	4.2e-75	287.7	Bifidobacteriales													Bacteria	2BG6D@1,2IR67@201174,32A37@2,4D18W@85004	NA|NA|NA		
NIOIMGPL_00167	398513.BBNG_00556	6.4e-290	1002.7	Bifidobacteriales													Bacteria	2IHFB@201174,4CZ17@85004,COG1075@1,COG1075@2	NA|NA|NA	S	PGAP1-like protein
NIOIMGPL_00168	702459.BBPR_0637	1.1e-280	971.8	Bifidobacteriales	purB	GO:0003674,GO:0003824,GO:0004018,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000			iAF1260.b1131,iBWG_1329.BWG_0979,iE2348C_1286.E2348C_1272,iEC042_1314.EC042_1202,iECABU_c1320.ECABU_c13450,iECDH10B_1368.ECDH10B_1203,iECP_1309.ECP_1126,iECUMN_1333.ECUMN_1375,iETEC_1333.ETEC_1255,iEcHS_1320.EcHS_A1251,iEcolC_1368.EcolC_2472,iJO1366.b1131,iJR904.b1131,iLF82_1304.LF82_1774,iNRG857_1313.NRG857_05460,iY75_1357.Y75_RS05905,ic_1306.c1510	Bacteria	2GM71@201174,4CYV6@85004,COG0015@1,COG0015@2	NA|NA|NA	F	Adenylosuccinate lyase C-terminal
NIOIMGPL_00169	702459.BBPR_0636	0.0	1579.3	Bifidobacteriales													Bacteria	2GMAV@201174,4CYRT@85004,COG0392@1,COG0392@2	NA|NA|NA	S	Lysylphosphatidylglycerol synthase TM region
NIOIMGPL_00170	398513.BBNG_00553	8.1e-42	176.0	Bifidobacteriales	hup	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141		ko:K03530					ko00000,ko03032,ko03036,ko03400				Bacteria	2IKQR@201174,4D11V@85004,COG0776@1,COG0776@2	NA|NA|NA	L	Belongs to the bacterial histone-like protein family
NIOIMGPL_00171	702459.BBPR_0634	1.9e-275	954.5	Bifidobacteriales	pafA	GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170	6.3.1.19	ko:K13571		M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051				Bacteria	2GMC6@201174,4CZ12@85004,COG0638@1,COG0638@2	NA|NA|NA	O	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NIOIMGPL_00172	398513.BBNG_00551	1.6e-10	71.6	Bifidobacteriales	pup			ko:K13570					ko00000,ko04121				Bacteria	2B5FT@1,2GV5R@201174,31YAF@2,4D1NH@85004	NA|NA|NA	S	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
NIOIMGPL_00173	398513.BBNG_00550	2e-157	561.6	Bifidobacteriales	hisN		3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000				Bacteria	2HGP2@201174,4CYWZ@85004,COG0483@1,COG0483@2	NA|NA|NA	G	Inositol monophosphatase family
NIOIMGPL_00174	398513.BBNG_00549	2.4e-231	807.7	Bifidobacteriales	dop	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.5.1.119,6.3.1.19	ko:K13571,ko:K20814		M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051				Bacteria	2GJGI@201174,4CZAN@85004,COG4122@1,COG4122@2	NA|NA|NA	S	Pup-ligase protein
NIOIMGPL_00175	702459.BBPR_0631	4.3e-62	243.8	Bifidobacteriales	dop	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.5.1.119,6.3.1.19	ko:K13571,ko:K20814		M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051				Bacteria	2GJGI@201174,4CZAN@85004,COG4122@1,COG4122@2	NA|NA|NA	S	Pup-ligase protein
NIOIMGPL_00176	702459.BBPR_0630	0.0	1082.4	Bifidobacteriales	arc	GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369		ko:K13525,ko:K13527	ko03050,ko04141,ko05134,map03050,map04141,map05134	M00342,M00400,M00403			ko00000,ko00001,ko00002,ko03019,ko03051,ko04131,ko04147	3.A.16.1			Bacteria	2GMR1@201174,4CZ86@85004,COG1222@1,COG1222@2	NA|NA|NA	O	AAA ATPase forming ring-shaped complexes
NIOIMGPL_00177	702459.BBPR_0629	6.6e-139	500.0	Bifidobacteriales	serB		3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009				Bacteria	2GJDH@201174,4CYWC@85004,COG0560@1,COG0560@2	NA|NA|NA	E	haloacid dehalogenase-like hydrolase
NIOIMGPL_00178	398513.BBNG_00546	4.3e-183	647.1	Bifidobacteriales	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.1.176,2.1.2.9	ko:K00604,ko:K03500	ko00670,ko00970,map00670,map00970		R03940	RC00026,RC00165	ko00000,ko00001,ko01000,ko03009			iECABU_c1320.ECABU_c37050,iECUMN_1333.ECUMN_3761,ic_1306.c4048	Bacteria	2GKH5@201174,4CZ8C@85004,COG0223@1,COG0223@2	NA|NA|NA	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NIOIMGPL_00179	398513.BBNG_00545	3.2e-135	487.6	Bifidobacteriales			3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120		R05287	RC00697	ko00000,ko00001,ko01000				Bacteria	2I8XE@201174,4CZGV@85004,COG1011@1,COG1011@2	NA|NA|NA	S	Haloacid dehalogenase-like hydrolase
NIOIMGPL_00180	702459.BBPR_0626	0.0	1475.3	Bifidobacteriales	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576		ko:K04066	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	2GKES@201174,4D04J@85004,COG1198@1,COG1198@2	NA|NA|NA	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NIOIMGPL_00181	702459.BBPR_0625	5.9e-74	283.5	Bifidobacteriales	metK	GO:0000096,GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006556,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009069,GO:0009108,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0019752,GO:0019899,GO:0030312,GO:0030554,GO:0030955,GO:0031420,GO:0032553,GO:0032555,GO:0032559,GO:0033353,GO:0034641,GO:0035375,GO:0035639,GO:0036094,GO:0040007,GO:0042278,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046872,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901605,GO:1901657	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000			iJN678.metX,iJN746.PP_4967,iYL1228.KPN_03375	Bacteria	2GJ4U@201174,4CZ5D@85004,COG0192@1,COG0192@2	NA|NA|NA	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NIOIMGPL_00182	398513.BBNG_00541	1.1e-53	215.7	Bifidobacteriales	rpoZ	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400				Bacteria	2IQHU@201174,4D12C@85004,COG1758@1,COG1758@2	NA|NA|NA	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NIOIMGPL_00183	702459.BBPR_0623	0.0	1227.2	Bifidobacteriales	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_1259,iECIAI39_1322.ECIAI39_3015	Bacteria	2GJIJ@201174,4CZ1T@85004,COG0129@1,COG0129@2	NA|NA|NA	H	Belongs to the IlvD Edd family
NIOIMGPL_00184	398513.BBNG_00539	6.7e-164	583.2	Bifidobacteriales	gmk		1.1.1.23,2.7.4.8	ko:K00013,ko:K00942	ko00230,ko00340,ko01100,ko01110,ko01230,map00230,map00340,map01100,map01110,map01230	M00026,M00050	R00332,R01158,R01163,R02090,R03012	RC00002,RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000				Bacteria	2GN40@201174,4CZPZ@85004,COG2852@1,COG2852@2	NA|NA|NA	S	Protein conserved in bacteria
NIOIMGPL_00185	702459.BBPR_0620	0.0	1774.6	Bifidobacteriales	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	2GJD5@201174,4CZ3T@85004,COG1048@1,COG1048@2	NA|NA|NA	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NIOIMGPL_00186	702459.BBPR_0619	0.0	1597.4	Bifidobacteriales	ctpE	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132		ko:K12952					ko00000,ko01000	3.A.3.23			Bacteria	2GJJC@201174,4CYS1@85004,COG0474@1,COG0474@2	NA|NA|NA	P	E1-E2 ATPase
NIOIMGPL_00187	702459.BBPR_0618	4e-110	404.1	Bifidobacteriales													Bacteria	2AVVG@1,2INFG@201174,31MP9@2,4D12J@85004	NA|NA|NA		
NIOIMGPL_00188	398513.BBNG_00535	1.4e-247	861.7	Bifidobacteriales	trmA	GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0019843,GO:0030488,GO:0030696,GO:0030697,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363	2.1.1.190,2.1.1.35	ko:K00557,ko:K03215					ko00000,ko01000,ko03009,ko03016				Bacteria	2GIR3@201174,4CYYN@85004,COG2265@1,COG2265@2	NA|NA|NA	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NIOIMGPL_00189	702459.BBPR_0616	7.5e-130	469.9	Bifidobacteriales													Bacteria	2AVV0@1,2GJKP@201174,31MNQ@2,4CYQX@85004	NA|NA|NA	S	Protein of unknown function (DUF3159)
NIOIMGPL_00190	702459.BBPR_0615	3e-137	494.6	Bifidobacteriales													Bacteria	28J4D@1,2GJYC@201174,2Z90C@2,4CZG1@85004	NA|NA|NA	S	Protein of unknown function (DUF3710)
NIOIMGPL_00191	702459.BBPR_0614	3.7e-170	604.0	Bifidobacteriales	exoA		3.1.11.2	ko:K01142	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	2GKIS@201174,4CYVB@85004,COG0708@1,COG0708@2	NA|NA|NA	L	Endonuclease/Exonuclease/phosphatase family
NIOIMGPL_00192	398513.BBNG_00531	8.7e-270	935.6	Bifidobacteriales	pepC	GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.4.22.40	ko:K01372					ko00000,ko01000,ko01002				Bacteria	2HCVR@201174,4CZD8@85004,COG3579@1,COG3579@2	NA|NA|NA	E	Peptidase C1-like family
NIOIMGPL_00193	398513.BBNG_00530	3.1e-309	1067.0	Bifidobacteriales	oppA			ko:K02035	ko02024,map02024	M00239			ko00000,ko00001,ko00002,ko02000	3.A.1.5			Bacteria	2GJ9N@201174,4CZ3S@85004,COG0747@1,COG0747@2	NA|NA|NA	E	Bacterial extracellular solute-binding proteins, family 5 Middle
NIOIMGPL_00194	398513.BBNG_00529	0.0	1228.0	Bifidobacteriales	oppD			ko:K02031,ko:K02032	ko02024,map02024	M00239			ko00000,ko00001,ko00002,ko02000	3.A.1.5			Bacteria	2H3HY@201174,4CYU0@85004,COG1123@1,COG4172@2	NA|NA|NA	P	Belongs to the ABC transporter superfamily
NIOIMGPL_00195	398513.BBNG_00528	3.5e-166	590.9	Bifidobacteriales	dppC			ko:K02034	ko02024,map02024	M00239			ko00000,ko00001,ko00002,ko02000	3.A.1.5			Bacteria	2GJ9E@201174,4CYQF@85004,COG1173@1,COG1173@2	NA|NA|NA	EP	N-terminal TM domain of oligopeptide transport permease C
NIOIMGPL_00196	398513.BBNG_00527	7.9e-177	626.3	Bifidobacteriales	appB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085		ko:K02033	ko02024,map02024	M00239			ko00000,ko00001,ko00002,ko02000	3.A.1.5			Bacteria	2GJ2C@201174,4CYS5@85004,COG0601@1,COG0601@2	NA|NA|NA	EP	Binding-protein-dependent transport system inner membrane component
NIOIMGPL_00197	398513.BBNG_00526	4.7e-185	653.7	Bifidobacteriales	xerC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K03733,ko:K04763					ko00000,ko03036				Bacteria	2GNDP@201174,4CZCX@85004,COG4974@1,COG4974@2	NA|NA|NA	D	Belongs to the 'phage' integrase family. XerC subfamily
NIOIMGPL_00198	398513.BBNG_00525	7.3e-42	176.0	Bifidobacteriales													Bacteria	2BGJ3@1,2IR91@201174,32AHC@2,4D17H@85004	NA|NA|NA		
NIOIMGPL_00199	398513.BBNG_00524	3.2e-192	677.6	Bifidobacteriales	tyrA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.3.1.12,1.3.1.43	ko:K00210,ko:K00220,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025,M00040	R00732,R01728	RC00125	ko00000,ko00001,ko00002,ko01000				Bacteria	2GKB4@201174,4CYV2@85004,COG0287@1,COG0287@2	NA|NA|NA	E	Prephenate dehydrogenase
NIOIMGPL_00200	398513.BBNG_00523	6.5e-198	696.4	Bifidobacteriales	pheA		1.3.1.12,4.2.1.51,5.4.99.5	ko:K04517,ko:K04518,ko:K14170	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715,R01728	RC00125,RC00360,RC03116	ko00000,ko00001,ko00002,ko01000				Bacteria	2GJQ5@201174,4CZ61@85004,COG0077@1,COG0077@2	NA|NA|NA	E	Prephenate dehydratase
NIOIMGPL_00201	702459.BBPR_0604	8.4e-80	303.1	Bifidobacteriales													Bacteria	2E9EF@1,2IKWQ@201174,333MW@2,4D10T@85004	NA|NA|NA		
NIOIMGPL_00202	398513.BBNG_00521	0.0	1268.1	Bifidobacteriales	typA	GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840		ko:K06207					ko00000				Bacteria	2GJUJ@201174,4CYX3@85004,COG1217@1,COG1217@2	NA|NA|NA	T	Elongation factor G C-terminus
NIOIMGPL_00203	398513.BBNG_00520	4.4e-236	823.5	Bifidobacteriales	iscS1		2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122		R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029				Bacteria	2GKUT@201174,4CZVW@85004,COG1104@1,COG1104@2	NA|NA|NA	E	Aminotransferase class-V
NIOIMGPL_00204	398513.BBNG_00519	2.4e-164	584.7	Bifidobacteriales	nadC	GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0030312,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000				Bacteria	2GV9P@201174,4CZWA@85004,COG0157@1,COG0157@2	NA|NA|NA	H	Quinolinate phosphoribosyl transferase, N-terminal domain
NIOIMGPL_00205	398513.BBNG_00518	0.0	1077.4	Bifidobacteriales	nadB	GO:0008150,GO:0040007	1.3.5.4,1.4.3.16,2.4.2.19	ko:K00244,ko:K00278,ko:K00767	ko00020,ko00190,ko00250,ko00620,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00250,map00620,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00115,M00150,M00173	R00357,R00481,R02164,R03348	RC00006,RC00045,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000			iNJ661.Rv1595	Bacteria	2I2IJ@201174,4D01P@85004,COG0029@1,COG0029@2	NA|NA|NA	H	Catalyzes the oxidation of L-aspartate to iminoaspartate
NIOIMGPL_00206	398513.BBNG_00517	3.1e-250	870.5	Bifidobacteriales	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000				Bacteria	2GM59@201174,4D0AI@85004,COG0379@1,COG0379@2	NA|NA|NA	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NIOIMGPL_00207	398513.BBNG_00516	8.6e-150	536.2	Bifidobacteriales	nrtR		3.6.1.55	ko:K03574					ko00000,ko01000,ko03400				Bacteria	2GNMT@201174,4CZNZ@85004,COG1051@1,COG1051@2	NA|NA|NA	F	NUDIX hydrolase
NIOIMGPL_00208	398513.BBNG_00515	6e-112	410.2	Bifidobacteriales	scpB			ko:K06024					ko00000,ko03036				Bacteria	2GISY@201174,4D0QW@85004,COG1386@1,COG1386@2	NA|NA|NA	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NIOIMGPL_00209	398513.BBNG_00514	1.2e-149	535.8	Bifidobacteriales	scpA			ko:K05896					ko00000,ko03036				Bacteria	2GN1U@201174,4CYRV@85004,COG1354@1,COG1354@2	NA|NA|NA	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NIOIMGPL_00210	398513.BBNG_00513	1.9e-46	192.2	Bifidobacteriales	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944		ko:K03496					ko00000,ko03036,ko04812				Bacteria	2GJX3@201174,4CYV4@85004,COG1192@1,COG1192@2	NA|NA|NA	D	CobQ CobB MinD ParA nucleotide binding domain protein
NIOIMGPL_00211	78344.BIGA_0653	4.9e-50	204.1	Bifidobacteriales	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944		ko:K03496					ko00000,ko03036,ko04812				Bacteria	2GJX3@201174,4CYV4@85004,COG1192@1,COG1192@2	NA|NA|NA	D	CobQ CobB MinD ParA nucleotide binding domain protein
NIOIMGPL_00212	702459.BBPR_0594	2.9e-179	634.4	Bifidobacteriales	xerD	GO:0008150,GO:0040007		ko:K03733,ko:K04763					ko00000,ko03036				Bacteria	2GNDP@201174,4CZ69@85004,COG4974@1,COG4974@2	NA|NA|NA	D	recombinase XerD
NIOIMGPL_00213	398513.BBNG_00511	9.6e-62	242.7	Bifidobacteriales	rplT	GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141		ko:K02887	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	2IHTN@201174,4D0QF@85004,COG0292@1,COG0292@2	NA|NA|NA	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NIOIMGPL_00214	398513.BBNG_00510	2.1e-25	120.9	Bifidobacteriales	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904		ko:K02916	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	2HZRM@201174,4D1EV@85004,COG0291@1,COG0291@2	NA|NA|NA	J	Ribosomal protein L35
NIOIMGPL_00215	398513.BBNG_00509	7e-103	380.2	Bifidobacteriales	infC	GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767		ko:K02520					ko00000,ko03012,ko03029				Bacteria	2GJGT@201174,4CZA3@85004,COG0290@1,COG0290@2	NA|NA|NA	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NIOIMGPL_00217	702459.BBPR_0588	8e-134	483.0	Bifidobacteriales			2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100		R00619	RC00002,RC00017	ko00000,ko00001,ko01000				Bacteria	2HQZZ@201174,4CZBY@85004,COG1564@1,COG1564@2	NA|NA|NA	H	Thiamin pyrophosphokinase, vitamin B1 binding domain
NIOIMGPL_00218	398513.BBNG_00506	1e-198	699.1	Bifidobacteriales	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009986,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019362,GO:0019637,GO:0019674,GO:0022610,GO:0034641,GO:0036094,GO:0043891,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044464,GO:0044650,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051704,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0097159,GO:0140030,GO:0140032,GO:1901265,GO:1901360,GO:1901363,GO:1901564	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147			iJR904.b1416,iJR904.b1417	Bacteria	2GJK4@201174,4CZ97@85004,COG0057@1,COG0057@2	NA|NA|NA	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NIOIMGPL_00219	702459.BBPR_0586	8.4e-93	346.3	Bifidobacteriales	ybaK	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0043907,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360		ko:K03976					ko00000,ko01000,ko03016				Bacteria	2IHS8@201174,4CZFI@85004,COG2606@1,COG2606@2	NA|NA|NA	J	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NIOIMGPL_00221	398513.BBNG_00503	2.2e-179	634.8	Bifidobacteriales	ispH		1.17.7.4,2.7.4.25	ko:K00945,ko:K02945,ko:K03527	ko00240,ko00900,ko01100,ko01110,ko01130,ko03010,map00240,map00900,map01100,map01110,map01130,map03010	M00052,M00096,M00178	R00158,R00512,R01665,R05884,R08210	RC00002,RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011			iIT341.HP0400,iLJ478.TM1444	Bacteria	2GIZ7@201174,4CZ8B@85004,COG0761@1,COG0761@2	NA|NA|NA	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NIOIMGPL_00222	398513.BBNG_00502	9.1e-194	682.6	Bifidobacteriales	galM		5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000				Bacteria	2GJ0H@201174,4CYWN@85004,COG2017@1,COG2017@2	NA|NA|NA	G	Aldose 1-epimerase
NIOIMGPL_00223	702459.BBPR_0583	2e-64	251.5	Bifidobacteriales													Bacteria	29M53@1,2GTWX@201174,3082I@2,4D1EJ@85004	NA|NA|NA		
NIOIMGPL_00224	398513.BBNG_00499	2.1e-114	418.3	Bifidobacteriales	sigH			ko:K03088					ko00000,ko03021				Bacteria	2GJ02@201174,4CZ09@85004,COG1595@1,COG1595@2	NA|NA|NA	K	Belongs to the sigma-70 factor family. ECF subfamily
NIOIMGPL_00225	398513.BBNG_00498	6.3e-296	1022.7	Bifidobacteriales	murE		6.3.2.13,6.3.2.7	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100		R02786,R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011				Bacteria	2GIS2@201174,4CZAF@85004,COG0769@1,COG0769@2	NA|NA|NA	M	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NIOIMGPL_00226	398513.BBNG_00497	9.8e-191	672.5	Bifidobacteriales													Bacteria	2GJUD@201174,4CZT9@85004,COG2348@1,COG2348@2	NA|NA|NA	V	Acetyltransferase (GNAT) domain
NIOIMGPL_00227	398513.BBNG_00496	2.2e-229	801.2	Bifidobacteriales			2.6.1.33	ko:K20429			R02773	RC00006,RC00781	ko00000,ko01000				Bacteria	2GKBC@201174,4D083@85004,COG0399@1,COG0399@2	NA|NA|NA	M	DegT/DnrJ/EryC1/StrS aminotransferase family
NIOIMGPL_00228	702459.BBPR_0578	9.5e-244	849.0	Bifidobacteriales	yxbA		6.3.1.12	ko:K17810					ko00000,ko01000				Bacteria	2GM4D@201174,4CZV2@85004,COG3919@1,COG3919@2	NA|NA|NA	S	ATP-grasp
NIOIMGPL_00229	398513.BBNG_00494	1.6e-128	465.3	Bifidobacteriales	racD		5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054		R00491	RC00302	ko00000,ko00001,ko01000				Bacteria	2H7J9@201174,4D05Z@85004,COG1794@1,COG1794@2	NA|NA|NA	G	Belongs to the aspartate glutamate racemases family
NIOIMGPL_00230	702459.BBPR_0576	0.0	2201.8	Bifidobacteriales	smc	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944		ko:K03529,ko:K19171					ko00000,ko02048,ko03036				Bacteria	2GK93@201174,4CZ8Q@85004,COG1196@1,COG1196@2	NA|NA|NA	D	Required for chromosome condensation and partitioning
NIOIMGPL_00231	398513.BBNG_00492	1.4e-282	978.4	Bifidobacteriales	folC	GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000			iNJ661.Rv2447c	Bacteria	2GJP2@201174,4CZG9@85004,COG0285@1,COG0285@2	NA|NA|NA	H	Mur ligase middle domain
NIOIMGPL_00233	398513.BBNG_00491	9.6e-97	359.4	Bifidobacteriales			3.6.1.55	ko:K03574					ko00000,ko01000,ko03400				Bacteria	2IKKB@201174,4CZS4@85004,COG1051@1,COG1051@2	NA|NA|NA	F	NUDIX domain
NIOIMGPL_00234	398513.BBNG_00490	0.0	1083.6	Bifidobacteriales	pepP		3.4.11.9	ko:K01262					ko00000,ko01000,ko01002				Bacteria	2GM7D@201174,4CZIA@85004,COG0006@1,COG0006@2	NA|NA|NA	E	Aminopeptidase P, N-terminal domain
NIOIMGPL_00235	398513.BBNG_00489	0.0	1116.3	Bifidobacteriales				ko:K02031,ko:K02032	ko02024,map02024	M00239			ko00000,ko00001,ko00002,ko02000	3.A.1.5			Bacteria	2H3HY@201174,4CYU0@85004,COG1123@1,COG4172@2	NA|NA|NA	P	Belongs to the ABC transporter superfamily
NIOIMGPL_00236	702459.BBPR_0570	8.7e-191	672.9	Bifidobacteriales	dppC			ko:K02034	ko02024,map02024	M00239			ko00000,ko00001,ko00002,ko02000	3.A.1.5			Bacteria	2GKAW@201174,4CZ2Y@85004,COG1173@1,COG1173@2	NA|NA|NA	EP	Binding-protein-dependent transport system inner membrane component
NIOIMGPL_00237	702459.BBPR_0569	6.7e-185	653.3	Bifidobacteriales	dppB			ko:K02033	ko02024,map02024	M00239			ko00000,ko00001,ko00002,ko02000	3.A.1.5			Bacteria	2GJ2C@201174,4CZSV@85004,COG0601@1,COG0601@2	NA|NA|NA	EP	Binding-protein-dependent transport system inner membrane component
NIOIMGPL_00238	1235797.C816_02294	9.4e-62	243.4	Oscillospiraceae													Bacteria	1U8NZ@1239,248X1@186801,2N6AM@216572,COG0714@1,COG0714@2	NA|NA|NA	S	AAA domain (dynein-related subfamily)
NIOIMGPL_00239	1007096.BAGW01000006_gene1879	8.4e-69	266.5	Oscillospiraceae													Bacteria	1U8NZ@1239,248X1@186801,2N6AM@216572,COG0714@1,COG0714@2	NA|NA|NA	S	AAA domain (dynein-related subfamily)
NIOIMGPL_00240	1226322.HMPREF1545_01255	5.2e-112	410.6	Oscillospiraceae													Bacteria	1TSI1@1239,248YT@186801,2N6U6@216572,COG3864@1,COG3864@2	NA|NA|NA	S	Putative metallopeptidase domain
NIOIMGPL_00242	1437610.BREU_1933	6.7e-09	65.9	Bifidobacteriales													Bacteria	2GJV7@201174,4D04H@85004,COG1609@1,COG1609@2	NA|NA|NA	K	helix_turn _helix lactose operon repressor
NIOIMGPL_00243	702459.BBPR_0013	6.1e-229	799.7	Bifidobacteriales													Bacteria	2GIVB@201174,4D077@85004,COG2267@1,COG2267@2	NA|NA|NA	I	Serine aminopeptidase, S33
NIOIMGPL_00244	702459.BBPR_0012	2.2e-189	668.3	Bifidobacteriales													Bacteria	2GJV7@201174,4CZUG@85004,COG1609@1,COG1609@2	NA|NA|NA	K	Periplasmic binding protein domain
NIOIMGPL_00245	702459.BBPR_0011	3.5e-187	660.6	Bifidobacteriales													Bacteria	2GNEY@201174,4D05A@85004,COG3507@1,COG3507@2	NA|NA|NA	G	Glycosyl hydrolases family 43
NIOIMGPL_00247	1437600.JDUI01000001_gene619	9.1e-20	103.2	Bifidobacteriales	abfA1		3.2.1.55	ko:K01209	ko00520,map00520		R01762		ko00000,ko00001,ko01000		GH51		Bacteria	2GMAK@201174,4CYXS@85004,COG3534@1,COG3534@2	NA|NA|NA	G	arabinose metabolic process
NIOIMGPL_00248	398513.BBNG_01786	4.6e-73	280.8	Bifidobacteriales		GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944											Bacteria	2GKZP@201174,4D0XB@85004,COG3266@1,COG3266@2	NA|NA|NA	S	Transmembrane domain of unknown function (DUF3566)
NIOIMGPL_00249	702459.BBPR_0006	0.0	1694.1	Bifidobacteriales	gyrA	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	5.99.1.3	ko:K02469					ko00000,ko01000,ko03032,ko03400				Bacteria	2GJ2Q@201174,4CYRP@85004,COG0188@1,COG0188@2	NA|NA|NA	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NIOIMGPL_00250	702459.BBPR_0005	0.0	1416.0	Bifidobacteriales	gyrB	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	5.99.1.3	ko:K02470					ko00000,ko01000,ko03032,ko03400				Bacteria	2GKGP@201174,4CZ47@85004,COG0187@1,COG0187@2	NA|NA|NA	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NIOIMGPL_00251	398513.BBNG_01782	3.2e-93	347.8	Bifidobacteriales													Bacteria	2GNQ4@201174,4D157@85004,COG5512@1,COG5512@2	NA|NA|NA	S	Protein of unknown function (DUF721)
NIOIMGPL_00252	702459.BBPR_0003	4e-240	837.0	Bifidobacteriales	recF	GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576		ko:K03629,ko:K07459	ko03440,map03440				ko00000,ko00001,ko03400				Bacteria	2GJCS@201174,4CZQT@85004,COG1195@1,COG1195@2	NA|NA|NA	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NIOIMGPL_00253	702459.BBPR_0002	6e-205	719.9	Bifidobacteriales	dnaN	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	2GJK3@201174,4CZTV@85004,COG0592@1,COG0592@2	NA|NA|NA	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NIOIMGPL_00254	398513.BBNG_01779	7e-300	1035.8	Bifidobacteriales	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837		ko:K02313	ko02020,ko04112,map02020,map04112				ko00000,ko00001,ko03032,ko03036				Bacteria	2GJKI@201174,4CZDW@85004,COG0593@1,COG0593@2	NA|NA|NA	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NIOIMGPL_00255	398513.BBNG_01778	4.5e-14	82.8	Bifidobacteriales	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02914	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	2GQFY@201174,4D1EF@85004,COG0230@1,COG0230@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL34 family
NIOIMGPL_00256	398513.BBNG_01775	6.7e-171	606.7	Bifidobacteriales	yidC			ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9			Bacteria	2GJBU@201174,4CYZ2@85004,COG0706@1,COG0706@2	NA|NA|NA	U	Membrane protein insertase, YidC Oxa1 family
NIOIMGPL_00257	702459.BBPR_1840	6.5e-93	346.7	Bifidobacteriales	jag			ko:K06346,ko:K09749					ko00000				Bacteria	2GPZK@201174,4CYQQ@85004,COG1847@1,COG1847@2	NA|NA|NA	S	Putative single-stranded nucleic acids-binding domain
NIOIMGPL_00258	702459.BBPR_1839	2.5e-124	451.4	Bifidobacteriales	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501					ko00000,ko01000,ko03009,ko03036				Bacteria	2GM9Z@201174,4CZ29@85004,COG0357@1,COG0357@2	NA|NA|NA	J	Specifically methylates the N7 position of a guanine in 16S rRNA
NIOIMGPL_00259	702459.BBPR_1838	8.5e-179	632.9	Bifidobacteriales	parA			ko:K03496					ko00000,ko03036,ko04812				Bacteria	2GMU7@201174,4CZ2D@85004,COG1192@1,COG1192@2	NA|NA|NA	D	CobQ CobB MinD ParA nucleotide binding domain protein
NIOIMGPL_00260	702459.BBPR_1837	1.8e-243	848.2	Bifidobacteriales	parB	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944		ko:K03497					ko00000,ko03000,ko03036,ko04812				Bacteria	2GNRN@201174,4CYUE@85004,COG1475@1,COG1475@2	NA|NA|NA	K	Belongs to the ParB family
NIOIMGPL_00261	398513.BBNG_01770	3.8e-202	710.7	Bifidobacteriales	trxB	GO:0000166,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9,4.3.1.9	ko:K00384,ko:K22345	ko00030,ko00450,map00030,map00450		R01544,R02016,R03596,R09372	RC00013,RC00544,RC02518,RC02873	ko00000,ko00001,ko01000			iPC815.YPO1374	Bacteria	2GKD2@201174,4CYU9@85004,COG0492@1,COG0492@2	NA|NA|NA	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NIOIMGPL_00262	398513.BBNG_01769	0.0	2504.6	Bifidobacteriales	murJ			ko:K03980					ko00000,ko01011,ko02000	2.A.66.4			Bacteria	2GKN0@201174,4CZ8M@85004,COG0515@1,COG0515@2,COG0728@1,COG0728@2	NA|NA|NA	KLT	MviN-like protein
NIOIMGPL_00263	702459.BBPR_1834	0.0	1346.6	Bifidobacteriales													Bacteria	2I2GZ@201174,4D2V9@85004,COG1361@1,COG1361@2	NA|NA|NA	M	Conserved repeat domain
NIOIMGPL_00264	398513.BBNG_01767	5.2e-124	450.3	Bifidobacteriales	deoC		3.6.1.13,3.6.1.17,3.6.1.55,3.6.1.61	ko:K01515,ko:K01518,ko:K03574,ko:K18445	ko00230,ko00240,map00230,map00240		R00184,R00969,R01054,R01232,R02805	RC00002	ko00000,ko00001,ko01000,ko03400				Bacteria	2GWEB@201174,4CZAV@85004,COG0494@1,COG0494@2	NA|NA|NA	L	Belongs to the Nudix hydrolase family
NIOIMGPL_00265	702459.BBPR_1832	2.8e-279	967.2	Bifidobacteriales	cca		2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018		R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019				Bacteria	2GMT1@201174,4CYUH@85004,COG0617@1,COG0617@2	NA|NA|NA	J	Probable RNA and SrmB- binding site of polymerase A
NIOIMGPL_00266	398513.BBNG_01765	6.7e-113	413.3	Bifidobacteriales													Bacteria	2E1BJ@1,2IKG0@201174,32WRF@2,4D0S1@85004	NA|NA|NA	S	LytR cell envelope-related transcriptional attenuator
NIOIMGPL_00267	398513.BBNG_01764	1.2e-167	595.9	Bifidobacteriales	ispE	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576	2.1.1.182,2.7.1.148	ko:K00919,ko:K02528,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096,M00582	R05634,R10716	RC00002,RC00003,RC01439,RC03257	ko00000,ko00001,ko00002,ko01000,ko02000,ko03009	3.A.1.29		iEC55989_1330.EC55989_1304,iLJ478.TM1383,iYO844.BSU00460	Bacteria	2GKXD@201174,4CZMW@85004,COG1947@1,COG1947@2	NA|NA|NA	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NIOIMGPL_00268	398513.BBNG_01763	6.3e-171	606.7	Bifidobacteriales	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182,2.1.1.184	ko:K00561,ko:K02528			R10716	RC00003,RC03257	br01600,ko00000,ko01000,ko01504,ko03009				Bacteria	2GKBT@201174,4CYS9@85004,COG0030@1,COG0030@2	NA|NA|NA	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NIOIMGPL_00269	702459.BBPR_1828	6.6e-212	743.4	Bifidobacteriales													Bacteria	2H4RU@201174,4CYY0@85004,COG3583@1,COG3583@2	NA|NA|NA	S	G5
NIOIMGPL_00271	702459.BBPR_1827	8.4e-151	540.0	Bifidobacteriales													Bacteria	2GN3N@201174,4CZBD@85004,COG1651@1,COG1651@2	NA|NA|NA	O	Thioredoxin
NIOIMGPL_00272	702459.BBPR_1826	0.0	1333.9	Bifidobacteriales													Bacteria	2GIV0@201174,4CYQG@85004,COG0515@1,COG0515@2	NA|NA|NA	KLT	Protein tyrosine kinase
NIOIMGPL_00273	398513.BBNG_01759	3.4e-174	617.5	Bifidobacteriales													Bacteria	2ICPH@201174,4CZJ7@85004,COG5340@1,COG5340@2	NA|NA|NA	K	Psort location Cytoplasmic, score
NIOIMGPL_00274	702459.BBPR_1824	4.3e-211	740.3	Bifidobacteriales	ugpC			ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606			ko00000,ko00001,ko00002,ko02000	3.A.1.1			Bacteria	2GJCM@201174,4CYU6@85004,COG3842@1,COG3842@2	NA|NA|NA	E	Belongs to the ABC transporter superfamily
NIOIMGPL_00275	702459.BBPR_1823	3.4e-100	370.9	Bifidobacteriales													Bacteria	2H4CW@201174,4D25Y@85004,COG2826@1,COG2826@2	NA|NA|NA	L	Helix-turn-helix domain
NIOIMGPL_00276	33035.JPJF01000013_gene4535	1.3e-38	166.0	Blautia	exsH		3.2.1.178,3.2.1.18,3.2.1.52	ko:K01186,ko:K02316,ko:K12373,ko:K20830	ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko03030,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map03030,map04142	M00079	R00022,R04018,R06004,R11316	RC00028,RC00049,RC00077	ko00000,ko00001,ko00002,ko01000,ko02042,ko03032,ko03110		GH16,GH20,GH33		Bacteria	1UUUJ@1239,25KCI@186801,3Y1HA@572511,COG1196@1,COG1196@2,COG2273@1,COG2273@2,COG5263@1,COG5263@2	NA|NA|NA	G	Putative cell wall binding repeat
NIOIMGPL_00277	33035.JPJF01000013_gene4535	7.6e-37	160.2	Blautia	exsH		3.2.1.178,3.2.1.18,3.2.1.52	ko:K01186,ko:K02316,ko:K12373,ko:K20830	ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko03030,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map03030,map04142	M00079	R00022,R04018,R06004,R11316	RC00028,RC00049,RC00077	ko00000,ko00001,ko00002,ko01000,ko02042,ko03032,ko03110		GH16,GH20,GH33		Bacteria	1UUUJ@1239,25KCI@186801,3Y1HA@572511,COG1196@1,COG1196@2,COG2273@1,COG2273@2,COG5263@1,COG5263@2	NA|NA|NA	G	Putative cell wall binding repeat
NIOIMGPL_00278	398513.BBNG_00325	3e-184	651.0	Bifidobacteriales	mutY		2.1.1.37,2.1.3.15,6.4.1.2	ko:K00558,ko:K01962,ko:K01963,ko:K03575	ko00061,ko00270,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03410,ko05206,map00061,map00270,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212,map03410,map05206	M00035,M00082,M00376	R00742,R04386,R04858	RC00003,RC00040,RC00253,RC00332,RC00367	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036,ko03400				Bacteria	2GJD9@201174,4CYRB@85004,COG1194@1,COG1194@2	NA|NA|NA	L	FES
NIOIMGPL_00279	702459.BBPR_0417	3.2e-93	347.8	Bifidobacteriales													Bacteria	2E5CN@1,2I2GJ@201174,3304R@2,4D0SD@85004	NA|NA|NA		
NIOIMGPL_00280	702459.BBPR_0418	0.0	2417.9	Bifidobacteriales	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400				Bacteria	2GJ81@201174,4CZ3W@85004,COG0085@1,COG0085@2	NA|NA|NA	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIOIMGPL_00281	702459.BBPR_0419	0.0	2548.1	Bifidobacteriales	rpoC	GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400				Bacteria	2GKWF@201174,4CZ1D@85004,COG0086@1,COG0086@2	NA|NA|NA	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIOIMGPL_00282	398513.BBNG_00329	2.9e-96	357.8	Bifidobacteriales													Bacteria	2IIXF@201174,4D0UU@85004,COG1716@1,COG1716@2	NA|NA|NA	T	Forkhead associated domain
NIOIMGPL_00283	398513.BBNG_00330	1.4e-67	262.7	Bifidobacteriales													Bacteria	2GRHT@201174,4D0W6@85004,COG5602@1,COG5602@2	NA|NA|NA	B	Belongs to the OprB family
NIOIMGPL_00284	702459.BBPR_0422	1.3e-165	589.0	Bifidobacteriales			3.1.3.16	ko:K01090,ko:K20074					ko00000,ko01000,ko01009				Bacteria	2GJ3M@201174,4CZNH@85004,COG0631@1,COG0631@2	NA|NA|NA	T	Sigma factor PP2C-like phosphatases
NIOIMGPL_00285	398513.BBNG_00332	1.3e-61	243.4	Bifidobacteriales													Bacteria	2HQBB@201174,4CZ3X@85004,COG1305@1,COG1305@2	NA|NA|NA	E	Transglutaminase-like superfamily
NIOIMGPL_00286	702459.BBPR_0423	1.5e-238	832.0	Bifidobacteriales													Bacteria	2HQBB@201174,4CZ3X@85004,COG1305@1,COG1305@2	NA|NA|NA	E	Transglutaminase-like superfamily
NIOIMGPL_00287	702459.BBPR_0424	1.8e-224	785.0	Bifidobacteriales													Bacteria	2GIWE@201174,4CZWT@85004,COG1721@1,COG1721@2	NA|NA|NA	S	Protein of unknown function DUF58
NIOIMGPL_00288	702459.BBPR_0425	8.2e-230	803.1	Bifidobacteriales				ko:K03924					ko00000,ko01000				Bacteria	2GK07@201174,4CZ3M@85004,COG0714@1,COG0714@2	NA|NA|NA	S	ATPase family associated with various cellular activities (AAA)
NIOIMGPL_00289	702459.BBPR_0426	0.0	3695.2	Bifidobacteriales				ko:K20276	ko02024,map02024				ko00000,ko00001				Bacteria	2GMKC@201174,4CZFT@85004,COG4733@1,COG4733@2	NA|NA|NA	S	Fibronectin type 3 domain
NIOIMGPL_00290	702459.BBPR_0427	2.6e-269	934.1	Bifidobacteriales													Bacteria	2GIW5@201174,4CZ9N@85004,COG0515@1,COG0515@2	NA|NA|NA	KLT	Protein tyrosine kinase
NIOIMGPL_00291	702459.BBPR_0428	0.0	2107.0	Bifidobacteriales	uvrD		3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430				ko00000,ko00001,ko01000,ko03400				Bacteria	2GJD0@201174,4CYQU@85004,COG0210@1,COG0210@2,COG2887@1,COG2887@2	NA|NA|NA	L	PD-(D/E)XK nuclease superfamily
NIOIMGPL_00292	398513.BBNG_00337	1.2e-188	665.6	Bifidobacteriales	uvrD		3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430				ko00000,ko00001,ko01000,ko03400				Bacteria	2GJD0@201174,4CYQU@85004,COG0210@1,COG0210@2,COG2887@1,COG2887@2	NA|NA|NA	L	PD-(D/E)XK nuclease superfamily
NIOIMGPL_00293	398513.BBNG_00338	0.0	2684.8	Bifidobacteriales	uvrD2		3.6.4.12	ko:K03657,ko:K07465	ko03420,ko03430,map03420,map03430				ko00000,ko00001,ko01000,ko03400				Bacteria	2GM2E@201174,4CZ49@85004,COG0210@1,COG0210@2,COG2887@1,COG2887@2	NA|NA|NA	L	Belongs to the helicase family. UvrD subfamily
NIOIMGPL_00294	702459.BBPR_0430	3.4e-155	554.3	Bifidobacteriales													Bacteria	2IKFK@201174,4D0XC@85004,COG0454@1,COG0454@2	NA|NA|NA	K	-acetyltransferase
NIOIMGPL_00295	702459.BBPR_0431	1.1e-248	865.5	Bifidobacteriales													Bacteria	2I2GK@201174,4CZ0T@85004,COG2271@1,COG2271@2	NA|NA|NA	G	Major Facilitator Superfamily
NIOIMGPL_00296	1280692.AUJL01000002_gene2530	2.3e-18	99.0	Clostridiaceae	appF			ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1V36J@1239,24C3R@186801,36EGD@31979,COG4608@1,COG4608@2	NA|NA|NA	P	Belongs to the ABC transporter superfamily
NIOIMGPL_00297	398513.BBNG_00343	6.4e-24	115.9	Bifidobacteriales	relB			ko:K07473					ko00000,ko02048				Bacteria	2GRBT@201174,4D1GU@85004,COG3077@1,COG3077@2	NA|NA|NA	L	RelB antitoxin
NIOIMGPL_00298	398513.BBNG_00344	2.8e-57	227.6	Bifidobacteriales													Bacteria	2IF22@201174,4D0MK@85004,COG3677@1,COG3677@2	NA|NA|NA	L	Transposase
NIOIMGPL_00299	702459.BBPR_0435	1e-132	479.6	Bifidobacteriales	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000			iJN678.dapB,iYO844.BSU22490	Bacteria	2GM2T@201174,4CZJ5@85004,COG0289@1,COG0289@2	NA|NA|NA	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NIOIMGPL_00300	398513.BBNG_00346	1.9e-161	575.1	Bifidobacteriales	dapA		4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000				Bacteria	2GJ34@201174,4CZ34@85004,COG0329@1,COG0329@2	NA|NA|NA	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIOIMGPL_00301	398513.BBNG_00347	4.4e-113	414.1	Bifidobacteriales	rnj	GO:0003674,GO:0005488,GO:0005515,GO:0042802		ko:K12574	ko03018,map03018				ko00000,ko00001,ko01000,ko03019				Bacteria	2GIW7@201174,4CZEJ@85004,COG0595@1,COG0595@2	NA|NA|NA	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NIOIMGPL_00302	398513.BBNG_00347	3.6e-210	737.3	Bifidobacteriales	rnj	GO:0003674,GO:0005488,GO:0005515,GO:0042802		ko:K12574	ko03018,map03018				ko00000,ko00001,ko01000,ko03019				Bacteria	2GIW7@201174,4CZEJ@85004,COG0595@1,COG0595@2	NA|NA|NA	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NIOIMGPL_00303	398513.BBNG_00348	0.0	1764.6	Bifidobacteriales	pepN		3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100		R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002				Bacteria	2GJJ4@201174,4CZH4@85004,COG0308@1,COG0308@2	NA|NA|NA	E	Peptidase family M1 domain
NIOIMGPL_00304	398513.BBNG_00349	5.5e-285	986.5	Bifidobacteriales				ko:K14645	ko02024,map02024				ko00000,ko00001,ko01000,ko01002,ko03110				Bacteria	2GMBS@201174,4CZY0@85004,COG1404@1,COG1404@2	NA|NA|NA	O	Subtilase family
NIOIMGPL_00305	398513.BBNG_00351	1.4e-256	891.7	Bifidobacteriales	glmM	GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130		R02060	RC00408	ko00000,ko00001,ko01000			iAF987.Gmet_1886,iLJ478.TM0184,iSB619.SA_RS11275,iSBO_1134.SBO_3206	Bacteria	2GN87@201174,4CYZX@85004,COG1109@1,COG1109@2	NA|NA|NA	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NIOIMGPL_00306	398513.BBNG_00352	2.6e-123	448.0	Bifidobacteriales	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462					ko00000,ko01000				Bacteria	2GNZ9@201174,4CZ7M@85004,COG0242@1,COG0242@2	NA|NA|NA	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NIOIMGPL_00307	702459.BBPR_0443	1.4e-270	938.3	Bifidobacteriales													Bacteria	2GJ39@201174,4CZC0@85004,COG4279@1,COG4279@2	NA|NA|NA	S	zinc finger
NIOIMGPL_00308	702459.BBPR_0444	1.5e-112	412.1	Bifidobacteriales	vsr			ko:K07458					ko00000,ko01000,ko03400				Bacteria	2IKPY@201174,4D0R6@85004,COG3727@1,COG3727@2	NA|NA|NA	L	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
NIOIMGPL_00309	398513.BBNG_00355	2.9e-229	800.8	Bifidobacteriales	aspB												Bacteria	2GJ7R@201174,4CZQP@85004,COG0436@1,COG0436@2	NA|NA|NA	E	Aminotransferase class-V
NIOIMGPL_00310	398513.BBNG_00356	5.6e-95	353.6	Bifidobacteriales	ppx	GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230		R03409	RC00002	ko00000,ko00001,ko01000				Bacteria	2GMME@201174,4CYW8@85004,COG0248@1,COG0248@2	NA|NA|NA	FP	Ppx/GppA phosphatase family
NIOIMGPL_00311	216816.GS08_08090	2.3e-37	161.0	Bifidobacteriales	ppx	GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230		R03409	RC00002	ko00000,ko00001,ko01000				Bacteria	2GMME@201174,4CYW8@85004,COG0248@1,COG0248@2	NA|NA|NA	FP	Ppx/GppA phosphatase family
NIOIMGPL_00312	398513.BBNG_00357	1.8e-128	465.3	Bifidobacteriales	tmp1												Bacteria	28XY7@1,2GN31@201174,2ZJU4@2,4CZQG@85004	NA|NA|NA	S	Domain of unknown function (DUF4391)
NIOIMGPL_00313	398513.BBNG_00358	9.3e-115	419.5	Bifidobacteriales	moeB		2.7.7.80	ko:K21029	ko04122,map04122		R07459	RC00043	ko00000,ko00001,ko01000				Bacteria	2GJB6@201174,4D06G@85004,COG0476@1,COG0476@2	NA|NA|NA	H	ThiF family
NIOIMGPL_00314	702459.BBPR_0449	1.7e-254	884.8	Bifidobacteriales	cdr	GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008		ko:K04085	ko04122,map04122				ko00000,ko00001,ko01000,ko03016				Bacteria	2I65D@201174,4D0GG@85004,COG0425@1,COG0425@2,COG0607@1,COG0607@2,COG2210@1,COG2210@2	NA|NA|NA	OP	Sulfurtransferase TusA
NIOIMGPL_00315	398513.BBNG_00360	2.8e-182	644.4	Bifidobacteriales	iunH1		3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100		R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000				Bacteria	2GP6N@201174,4CZ0Y@85004,COG1957@1,COG1957@2	NA|NA|NA	F	Inosine-uridine preferring nucleoside hydrolase
NIOIMGPL_00317	398513.BBNG_00363	1.9e-172	611.7	Bifidobacteriales				ko:K18353	ko01502,ko02020,map01502,map02020	M00651			ko00000,ko00001,ko00002,ko01504				Bacteria	2I2GX@201174,4CYTX@85004,COG3568@1,COG3568@2	NA|NA|NA	S	Endonuclease/Exonuclease/phosphatase family
NIOIMGPL_00318	398513.BBNG_00364	7.8e-43	179.5	Bifidobacteriales	xseB	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494	3.1.11.6	ko:K03602	ko03430,map03430				ko00000,ko00001,ko01000,ko03400				Bacteria	2GR0U@201174,4D18C@85004,COG1722@1,COG1722@2	NA|NA|NA	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NIOIMGPL_00319	702459.BBPR_0454	1.1e-272	945.3	Bifidobacteriales	xseA	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	3.1.11.6	ko:K03601	ko03430,map03430				ko00000,ko00001,ko01000,ko03400				Bacteria	2GJAS@201174,4CZU4@85004,COG1570@1,COG1570@2	NA|NA|NA	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NIOIMGPL_00320	398513.BBNG_00366	0.0	1249.2	Bifidobacteriales	nrdD	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0017076,GO:0018130,GO:0019001,GO:0019103,GO:0019438,GO:0019637,GO:0019692,GO:0030554,GO:0031250,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032556,GO:0032558,GO:0032559,GO:0032560,GO:0032564,GO:0032567,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0046872,GO:0046914,GO:0051065,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000			iECIAI39_1322.ECIAI39_4713,iPC815.YPO3454	Bacteria	2GMGA@201174,4CYV3@85004,COG1328@1,COG1328@2	NA|NA|NA	F	Anaerobic ribonucleoside-triphosphate reductase
NIOIMGPL_00321	398513.BBNG_00367	4.3e-140	503.8	Bifidobacteriales	nrdG	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0031250,GO:0032991,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576	1.97.1.4	ko:K04068			R04710		ko00000,ko01000			iE2348C_1286.E2348C_4563	Bacteria	2H0HA@201174,4CYSC@85004,COG0602@1,COG0602@2	NA|NA|NA	O	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NIOIMGPL_00323	398513.BBNG_00369	3.1e-32	144.1	Bifidobacteriales	hgdC												Bacteria	2I1VH@201174,4CZ6Y@85004,COG1924@1,COG1924@2,COG3580@1,COG3580@2,COG3581@1,COG3581@2	NA|NA|NA	I	CoA enzyme activase uncharacterised domain (DUF2229)
NIOIMGPL_00324	398513.BBNG_00369	0.0	3083.1	Bifidobacteriales	hgdC												Bacteria	2I1VH@201174,4CZ6Y@85004,COG1924@1,COG1924@2,COG3580@1,COG3580@2,COG3581@1,COG3581@2	NA|NA|NA	I	CoA enzyme activase uncharacterised domain (DUF2229)
NIOIMGPL_00325	702459.BBPR_0458	1.3e-108	399.1	Actinobacteria													Bacteria	28NJG@1,2GT1B@201174,30HV1@2	NA|NA|NA		
NIOIMGPL_00326	702459.BBPR_0459	5.9e-257	892.9	Bifidobacteriales	gshA		6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000				Bacteria	2GJPI@201174,4CYZP@85004,COG3572@1,COG3572@2	NA|NA|NA	H	Glutamate-cysteine ligase family 2(GCS2)
NIOIMGPL_00327	398513.BBNG_00372	0.0	2558.9	Bifidobacteriales	plyA3		3.2.1.18	ko:K01186,ko:K12547	ko00511,ko00600,ko04142,map00511,map00600,map04142		R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042		GH33		Bacteria	2I2HT@201174,4D0IE@85004,COG3064@1,COG3064@2,COG5434@1,COG5434@2	NA|NA|NA	M	Parallel beta-helix repeats
NIOIMGPL_00328	702459.BBPR_0460	6.4e-55	220.3	Bifidobacteriales	plyA3			ko:K12547					ko00000				Bacteria	2I2HT@201174,4D0IE@85004,COG5434@1,COG5434@2	NA|NA|NA	M	Parallel beta-helix repeats
NIOIMGPL_00329	398513.BBNG_00373	5.8e-89	333.6	Bifidobacteriales													Bacteria	2IIWT@201174,4D0WT@85004,COG1846@1,COG1846@2	NA|NA|NA	K	MarR family
NIOIMGPL_00330	702459.BBPR_0462	0.0	1155.2	Bifidobacteriales				ko:K06147,ko:K06148					ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21			Bacteria	2GITR@201174,4CZMX@85004,COG1132@1,COG1132@2	NA|NA|NA	V	ABC transporter, ATP-binding protein
NIOIMGPL_00331	702459.BBPR_0463	0.0	1299.3	Bifidobacteriales				ko:K06147					ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21			Bacteria	2GITR@201174,4CZPJ@85004,COG1132@1,COG1132@2	NA|NA|NA	V	ABC transporter transmembrane region
NIOIMGPL_00332	702459.BBPR_0464	3.4e-167	594.3	Bifidobacteriales				ko:K07001					ko00000				Bacteria	2I8R7@201174,4CZUH@85004,COG4667@1,COG4667@2	NA|NA|NA	S	Patatin-like phospholipase
NIOIMGPL_00333	398513.BBNG_00377	1.5e-152	545.4	Bifidobacteriales	murI	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100		R00260	RC00302	ko00000,ko00001,ko01000,ko01011				Bacteria	2GN4I@201174,4CZ54@85004,COG0796@1,COG0796@2	NA|NA|NA	M	Provides the (R)-glutamate required for cell wall biosynthesis
NIOIMGPL_00334	398513.BBNG_00378	1.8e-167	595.1	Bifidobacteriales	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000			iIT341.HP0566,iLJ478.TM1522	Bacteria	2GKUD@201174,4CYQP@85004,COG0253@1,COG0253@2	NA|NA|NA	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
NIOIMGPL_00335	398513.BBNG_00379	3.4e-115	421.0	Bifidobacteriales													Bacteria	2GMVK@201174,4CZN1@85004,COG4243@1,COG4243@2	NA|NA|NA	S	Vitamin K epoxide reductase
NIOIMGPL_00336	398513.BBNG_00380	2.5e-166	591.3	Bifidobacteriales	PPA1328		3.1.3.97	ko:K07053			R00188,R11188	RC00078	ko00000,ko01000				Bacteria	2GNAP@201174,4CYQ5@85004,COG0613@1,COG0613@2	NA|NA|NA	S	DNA polymerase alpha chain like domain
NIOIMGPL_00337	702459.BBPR_0469	6.1e-32	142.9	Bifidobacteriales													Bacteria	2AS45@1,2HZSD@201174,31HGW@2,4D1H9@85004	NA|NA|NA	S	Protein of unknown function (DUF3107)
NIOIMGPL_00338	702459.BBPR_0470	4.6e-245	853.6	Bifidobacteriales	mphA												Bacteria	2I8R6@201174,4CYPR@85004,COG3173@1,COG3173@2	NA|NA|NA	S	Aminoglycoside phosphotransferase
NIOIMGPL_00339	702459.BBPR_0471	1.5e-280	971.5	Bifidobacteriales	uvrD2	GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430				ko00000,ko00001,ko01000,ko03400				Bacteria	2GKRW@201174,4CZ3A@85004,COG0210@1,COG0210@2	NA|NA|NA	L	DNA helicase
NIOIMGPL_00340	702459.BBPR_0472	8.2e-285	985.7	Bifidobacteriales													Bacteria	2GJ9K@201174,4CYU7@85004,COG5282@1,COG5282@2	NA|NA|NA	S	Zincin-like metallopeptidase
NIOIMGPL_00341	398513.BBNG_00386	2.5e-59	235.0	Bifidobacteriales	lon			ko:K07177	ko02024,map02024				ko00000,ko00001,ko01002				Bacteria	2GMFX@201174,4CYUP@85004,COG3480@1,COG3480@2	NA|NA|NA	T	Belongs to the peptidase S16 family
NIOIMGPL_00342	702459.BBPR_0473	7.1e-65	253.1	Bifidobacteriales	lon			ko:K07177	ko02024,map02024				ko00000,ko00001,ko01002				Bacteria	2GMFX@201174,4CYUP@85004,COG3480@1,COG3480@2	NA|NA|NA	T	Belongs to the peptidase S16 family
NIOIMGPL_00343	398513.BBNG_00387	5.7e-47	193.7	Bifidobacteriales													Bacteria	2B57P@1,2I89I@201174,32TPU@2,4D0P0@85004	NA|NA|NA	S	Protein of unknown function (DUF3052)
NIOIMGPL_00344	398513.BBNG_00388	8.1e-196	689.5	Bifidobacteriales				ko:K02529					ko00000,ko03000				Bacteria	2GJY9@201174,4CYU5@85004,COG1609@1,COG1609@2	NA|NA|NA	K	helix_turn _helix lactose operon repressor
NIOIMGPL_00345	398513.BBNG_00389	1.2e-61	242.3	Bifidobacteriales		GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464											Bacteria	2IQ7E@201174,4D14E@85004,COG0011@1,COG0011@2	NA|NA|NA	S	Thiamine-binding protein
NIOIMGPL_00346	398513.BBNG_00390	6.6e-43	179.5	Bifidobacteriales	thiD		2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17	ko:K00941,ko:K03147,ko:K14153	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R03472,R04509,R10712	RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_2909	Bacteria	2GKZM@201174,4CYQA@85004,COG0351@1,COG0351@2	NA|NA|NA	H	Phosphomethylpyrimidine kinase
NIOIMGPL_00347	398513.BBNG_00390	1.7e-25	121.3	Bifidobacteriales	thiD		2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17	ko:K00941,ko:K03147,ko:K14153	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R03472,R04509,R10712	RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_2909	Bacteria	2GKZM@201174,4CYQA@85004,COG0351@1,COG0351@2	NA|NA|NA	H	Phosphomethylpyrimidine kinase
NIOIMGPL_00348	398513.BBNG_00391	6.9e-231	806.2	Bifidobacteriales				ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403			ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1			Bacteria	2I5C1@201174,4D0DP@85004,COG1222@1,COG1222@2	NA|NA|NA	O	AAA domain (Cdc48 subfamily)
NIOIMGPL_00349	398513.BBNG_00393	1.3e-84	318.9	Bifidobacteriales													Bacteria	2CK5B@1,2HU05@201174,2ZYDK@2,4D0JT@85004	NA|NA|NA		
NIOIMGPL_00350	398513.BBNG_00394	0.0	1842.0	Bifidobacteriales	thiC	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17	ko:K00788,ko:K03147,ko:K14153	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R03472,R04509,R10712	RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000			iYO844.BSU08790,iYO844.BSU38290	Bacteria	2GJ3Y@201174,4D2W5@85004,COG0352@1,COG0352@2,COG0422@1,COG0422@2	NA|NA|NA	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NIOIMGPL_00351	398513.BBNG_00395	6.8e-159	566.6	Bifidobacteriales	thiM		2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	2IC73@201174,4CZU8@85004,COG2145@1,COG2145@2	NA|NA|NA	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NIOIMGPL_00352	702459.BBPR_0482	0.0	2786.9	Bifidobacteriales	lacZ	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100		R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000				Bacteria	2GMAT@201174,4CYRA@85004,COG1196@1,COG1196@2,COG3250@1,COG3250@2	NA|NA|NA	G	Domain of unknown function (DUF4982)
NIOIMGPL_00353	702459.BBPR_0482	1.4e-123	449.1	Bifidobacteriales	lacZ	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100		R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000				Bacteria	2GMAT@201174,4CYRA@85004,COG1196@1,COG1196@2,COG3250@1,COG3250@2	NA|NA|NA	G	Domain of unknown function (DUF4982)
NIOIMGPL_00354	702459.BBPR_0483	3.1e-289	1000.3	Bifidobacteriales	glyQS	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029			iSB619.SA_RS07880	Bacteria	2GIT3@201174,4CYZU@85004,COG0423@1,COG0423@2	NA|NA|NA	J	Catalyzes the attachment of glycine to tRNA(Gly)
NIOIMGPL_00355	398513.BBNG_00399	4.7e-246	856.7	Bifidobacteriales	dus	GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090											Bacteria	2GJ8I@201174,4CZFD@85004,COG0042@1,COG0042@2	NA|NA|NA	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NIOIMGPL_00356	398513.BBNG_00400	2.8e-230	804.3	Bifidobacteriales	ftsZ	GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363		ko:K03531	ko04112,map04112				ko00000,ko00001,ko02048,ko03036,ko04812				Bacteria	2GJWC@201174,4CZ10@85004,COG0206@1,COG0206@2	NA|NA|NA	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NIOIMGPL_00357	398513.BBNG_00401	4.3e-80	303.9	Bifidobacteriales	sepF	GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0051301,GO:0071840,GO:0090529		ko:K09772					ko00000,ko03036				Bacteria	2GNVH@201174,4D0RJ@85004,COG1799@1,COG1799@2	NA|NA|NA	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NIOIMGPL_00358	398513.BBNG_00402	3.7e-42	177.2	Bifidobacteriales	yggT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K02221					ko00000,ko02044				Bacteria	2GQI1@201174,4D17B@85004,COG0762@1,COG0762@2	NA|NA|NA	S	YGGT family
NIOIMGPL_00359	398513.BBNG_00404	9.7e-90	337.4	Bifidobacteriales			3.1.21.3	ko:K01153,ko:K02557,ko:K10352,ko:K18682	ko02030,ko02040,ko03018,ko04530,map02030,map02040,map03018,map04530				ko00000,ko00001,ko01000,ko02000,ko02035,ko02048,ko03019,ko04147,ko04812	1.A.30.1			Bacteria	2I2G9@201174,4CZ5W@85004,COG1566@1,COG1566@2	NA|NA|NA	V	DivIVA protein
NIOIMGPL_00360	398513.BBNG_00405	1.4e-100	372.5	Bifidobacteriales	lspA		3.4.23.36	ko:K03101	ko03060,map03060				ko00000,ko00001,ko01000,ko01002				Bacteria	2GKRX@201174,4D0WR@85004,COG0597@1,COG0597@2	NA|NA|NA	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NIOIMGPL_00361	398513.BBNG_00406	3.4e-177	627.5	Bifidobacteriales	rluD	GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180					ko00000,ko01000,ko03009,ko03016			iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432	Bacteria	2GIY1@201174,4CYYR@85004,COG0564@1,COG0564@2	NA|NA|NA	J	Responsible for synthesis of pseudouridine from uracil
NIOIMGPL_00363	398513.BBNG_00409	6e-63	246.5	Bifidobacteriales													Bacteria	2DMQA@1,2GPRU@201174,32SZE@2,4D1R8@85004	NA|NA|NA		
NIOIMGPL_00364	398513.BBNG_00410	2.3e-23	115.2	Bifidobacteriales	dapD	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000			iNJ661.Rv1201c	Bacteria	2GIZ9@201174,4CYVT@85004,COG2171@1,COG2171@2	NA|NA|NA	E	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
NIOIMGPL_00365	398513.BBNG_00410	5.9e-12	75.5	Bifidobacteriales	dapD	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000			iNJ661.Rv1201c	Bacteria	2GIZ9@201174,4CYVT@85004,COG2171@1,COG2171@2	NA|NA|NA	E	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
NIOIMGPL_00366	398513.BBNG_00412	3.7e-202	710.7	Bifidobacteriales	prfB	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576		ko:K02836					ko00000,ko03012				Bacteria	2GJ0F@201174,4CZJX@85004,COG1186@1,COG1186@2	NA|NA|NA	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NIOIMGPL_00367	398513.BBNG_00413	8.7e-201	706.4	Bifidobacteriales	ftsE	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363		ko:K09811,ko:K09812	ko02010,map02010	M00256			ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140			Bacteria	2GJE1@201174,4CYYQ@85004,COG2884@1,COG2884@2	NA|NA|NA	D	Cell division ATP-binding protein FtsE
NIOIMGPL_00368	398513.BBNG_00414	2.4e-159	568.2	Bifidobacteriales	ftsX	GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0042173,GO:0042221,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0090529,GO:1902531		ko:K09811,ko:K09812	ko02010,map02010	M00256			ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140			Bacteria	2GJMA@201174,4CZSQ@85004,COG2177@1,COG2177@2	NA|NA|NA	D	Part of the ABC transporter FtsEX involved in cellular division
NIOIMGPL_00369	702459.BBPR_0498	2.5e-163	582.0	Bifidobacteriales	usp		3.5.1.28	ko:K21471,ko:K22409					ko00000,ko01000,ko01002,ko01011		CBM50		Bacteria	2GZG8@201174,4CYQJ@85004,COG3942@1,COG3942@2	NA|NA|NA	D	CHAP domain protein
NIOIMGPL_00370	398513.BBNG_00416	3e-76	291.2	Bifidobacteriales	smpB	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564		ko:K03664					ko00000				Bacteria	2GJX1@201174,4CZG4@85004,COG0691@1,COG0691@2	NA|NA|NA	J	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NIOIMGPL_00371	702459.BBPR_0500	1.9e-146	525.0	Bifidobacteriales	rluA		5.4.99.28,5.4.99.29	ko:K06177					ko00000,ko01000,ko03009,ko03016				Bacteria	2GJ2Z@201174,4CZB2@85004,COG0564@1,COG0564@2	NA|NA|NA	J	RNA pseudouridylate synthase
NIOIMGPL_00372	1437610.BREU_1425	1e-81	309.7	Bifidobacteriales													Bacteria	2BFV3@1,2IT9I@201174,329QD@2,4D1CE@85004	NA|NA|NA		
NIOIMGPL_00374	398513.BBNG_00422	1e-189	669.8	Bifidobacteriales			2.7.11.1	ko:K08884,ko:K12132					ko00000,ko01000,ko01001				Bacteria	2I2GE@201174,4CZDF@85004,COG3170@1,COG3170@2	NA|NA|NA	NU	Tfp pilus assembly protein FimV
NIOIMGPL_00375	398513.BBNG_00423	1.5e-222	778.5	Bifidobacteriales	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000			iAPECO1_1312.APECO1_1814,iECOK1_1307.ECOK1_0174,iECS88_1305.ECS88_0183,iHN637.CLJU_RS06420,iUMN146_1321.UM146_23670,iUTI89_1310.UTI89_C0188	Bacteria	2GIRV@201174,4CZVC@85004,COG0743@1,COG0743@2	NA|NA|NA	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NIOIMGPL_00376	702459.BBPR_0507	1e-235	822.4	Bifidobacteriales	ispG	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000			iHN637.CLJU_RS06430,iJN678.gcpE	Bacteria	2GK2S@201174,4CYQB@85004,COG0821@1,COG0821@2	NA|NA|NA	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NIOIMGPL_00377	702459.BBPR_0508	1.4e-262	911.8	Bifidobacteriales													Bacteria	2I2GD@201174,4CZUD@85004,COG0657@1,COG0657@2	NA|NA|NA	I	acetylesterase activity
NIOIMGPL_00378	702459.BBPR_0509	2.7e-143	514.6	Bifidobacteriales	recO	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944		ko:K03584	ko03440,map03440				ko00000,ko00001,ko03400				Bacteria	2GK81@201174,4CZCN@85004,COG1381@1,COG1381@2	NA|NA|NA	L	Involved in DNA repair and RecF pathway recombination
NIOIMGPL_00379	398513.BBNG_00427	1.8e-155	555.1	Bifidobacteriales	uppS	GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617	2.5.1.31,2.5.1.86,2.5.1.88	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110		R06447,R09244,R09731	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006				Bacteria	2GIXF@201174,4CZAR@85004,COG0020@1,COG0020@2	NA|NA|NA	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NIOIMGPL_00380	702459.BBPR_0511	4.3e-191	673.7	Bifidobacteriales	ywqG												Bacteria	2GSR1@201174,4D1R0@85004,COG3878@1,COG3878@2	NA|NA|NA	S	Domain of unknown function (DUF1963)
NIOIMGPL_00381	1437609.BCAL_1171	3.1e-19	100.5	Bifidobacteriales	cscA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100		R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000		GH32	iE2348C_1286.E2348C_2556,iEC55989_1330.EC55989_2656,iECIAI1_1343.ECIAI1_2428	Bacteria	2GJ9T@201174,4CZ8W@85004,COG1621@1,COG1621@2	NA|NA|NA	G	Belongs to the glycosyl hydrolase 32 family
NIOIMGPL_00382	398513.BBNG_00429	3e-39	167.2	Bacteria	cscA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100		R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000		GH32	iE2348C_1286.E2348C_2556,iEC55989_1330.EC55989_2656,iECIAI1_1343.ECIAI1_2428	Bacteria	COG1621@1,COG1621@2	NA|NA|NA	G	Belongs to the glycosyl hydrolase 32 family
NIOIMGPL_00383	398513.BBNG_00430	0.0	2390.1	Bifidobacteriales	dnaE		2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	2GJ1P@201174,4CZKT@85004,COG0587@1,COG0587@2	NA|NA|NA	L	DNA polymerase III alpha subunit
NIOIMGPL_00384	702459.BBPR_0515	3.1e-96	358.2	Bifidobacteriales													Bacteria	2BHFF@1,2GV2H@201174,32BHI@2,4D1HU@85004	NA|NA|NA	S	zinc-ribbon domain
NIOIMGPL_00385	398513.BBNG_00432	2e-46	191.4	Bifidobacteriales	yhbY	GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275		ko:K07574					ko00000,ko03009				Bacteria	2IKSS@201174,4D10K@85004,COG1534@1,COG1534@2	NA|NA|NA	J	CRS1_YhbY
NIOIMGPL_00386	398513.BBNG_00433	0.0	1311.6	Bifidobacteriales			4.2.1.53	ko:K10254					ko00000,ko01000				Bacteria	2GKZ8@201174,4CYZK@85004,COG4716@1,COG4716@2	NA|NA|NA	S	MCRA family
NIOIMGPL_00389	398513.BBNG_00435	3.4e-202	710.7	Bifidobacteriales				ko:K07012					ko00000,ko01000,ko02048				Bacteria	2IAIA@201174,4CYRS@85004,COG2378@1,COG2378@2	NA|NA|NA	K	WYL domain
NIOIMGPL_00390	398513.BBNG_00436	1.3e-156	558.9	Bifidobacteriales	yvgN		1.1.1.346	ko:K06221			R08878	RC00089	ko00000,ko01000				Bacteria	2GJQ7@201174,4CZ1F@85004,COG0656@1,COG0656@2	NA|NA|NA	S	Aldo/keto reductase family
NIOIMGPL_00391	702459.BBPR_0520	1.6e-168	598.6	Bifidobacteriales	dkgA	GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008106,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0055114,GO:0071704,GO:1901575	1.1.1.346	ko:K06221			R08878	RC00089	ko00000,ko01000			iECH74115_1262.ECH74115_4323,iECSP_1301.ECSP_3988	Bacteria	2GJQ7@201174,4CZXR@85004,COG0656@1,COG0656@2	NA|NA|NA	C	Aldo/keto reductase family
NIOIMGPL_00392	702459.BBPR_0521	3.4e-76	290.8	Bifidobacteriales	yneG												Bacteria	2DMJC@1,2IHZV@201174,32RYJ@2,4D0UY@85004	NA|NA|NA	S	Domain of unknown function (DUF4186)
NIOIMGPL_00394	398513.BBNG_00441	8.9e-181	639.4	Bifidobacteriales	gmk		1.1.1.23,2.7.4.8	ko:K00013,ko:K00942	ko00230,ko00340,ko01100,ko01110,ko01230,map00230,map00340,map01100,map01110,map01230	M00026,M00050	R00332,R01158,R01163,R02090,R03012	RC00002,RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000				Bacteria	2HTNX@201174,4D0CP@85004,COG2852@1,COG2852@2	NA|NA|NA	S	Protein conserved in bacteria
NIOIMGPL_00395	398513.BBNG_00443	3.2e-256	890.6	Bifidobacteriales	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23,1.1.1.308	ko:K00013,ko:K15509	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000			iNJ661.Rv1599	Bacteria	2GKKA@201174,4CZ3E@85004,COG0141@1,COG0141@2	NA|NA|NA	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NIOIMGPL_00396	398513.BBNG_00444	3.7e-218	763.8	Bifidobacteriales	hisC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	2GJ9W@201174,4CZDT@85004,COG0079@1,COG0079@2	NA|NA|NA	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NIOIMGPL_00397	398513.BBNG_00445	3.2e-112	411.0	Bifidobacteriales	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23,2.6.1.9,3.1.3.15,4.2.1.19	ko:K00013,ko:K00817,ko:K01089,ko:K01693	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R01158,R01163,R03012,R03013,R03243,R03457	RC00006,RC00017,RC00099,RC00242,RC00463,RC00888,RC00932	ko00000,ko00001,ko00002,ko01000,ko01007			iECO111_1330.ECO111_2746,iECS88_1305.ECS88_2121,iJN746.PP_0289,iLJ478.TM1039,iSB619.SA_RS14130,iUMNK88_1353.UMNK88_2570	Bacteria	2GKMD@201174,4CZDD@85004,COG0131@1,COG0131@2	NA|NA|NA	E	Imidazoleglycerol-phosphate dehydratase
NIOIMGPL_00398	398513.BBNG_00446	1.7e-112	412.1	Bifidobacteriales													Bacteria	2EKCN@1,2GNIC@201174,33E2Y@2,4D0B5@85004	NA|NA|NA		
NIOIMGPL_00399	398513.BBNG_00447	4.8e-122	443.7	Bifidobacteriales	hisH	GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607		ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000				Bacteria	2GIYS@201174,4CZGA@85004,COG0118@1,COG0118@2	NA|NA|NA	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NIOIMGPL_00400	702459.BBPR_0529	1.7e-131	475.3	Bifidobacteriales	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16,5.3.1.24	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	M00023,M00026	R03509,R04640	RC00945	ko00000,ko00001,ko00002,ko01000				Bacteria	2GJ4V@201174,4CZEA@85004,COG0106@1,COG0106@2	NA|NA|NA	E	Histidine biosynthesis protein
NIOIMGPL_00401	398513.BBNG_00449	1.4e-283	981.5	Bifidobacteriales													Bacteria	2GKEK@201174,4CZIY@85004,COG4320@1,COG4320@2	NA|NA|NA	S	Uncharacterized protein conserved in bacteria (DUF2252)
NIOIMGPL_00402	398513.BBNG_00450	2.1e-265	921.0	Bifidobacteriales	glnA2	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727		R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147				Bacteria	2GJ2I@201174,4CZ0G@85004,COG0174@1,COG0174@2	NA|NA|NA	E	glutamine synthetase
NIOIMGPL_00403	398513.BBNG_00451	6e-139	500.7	Bifidobacteriales													Bacteria	2AZXA@1,2GQBM@201174,31S72@2,4D1E0@85004	NA|NA|NA	S	Domain of unknown function (DUF5067)
NIOIMGPL_00404	702459.BBPR_0534	5.5e-176	623.6	Bifidobacteriales													Bacteria	2HYIN@201174,4CYU1@85004,COG5479@1,COG5479@2	NA|NA|NA	M	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
NIOIMGPL_00405	702459.BBPR_0535	0.0	2686.8	Bifidobacteriales	hrpA	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K03578					ko00000,ko01000				Bacteria	2GIWX@201174,4CZ3C@85004,COG1643@1,COG1643@2	NA|NA|NA	L	Helicase associated domain (HA2)  Add an annotation
NIOIMGPL_00406	398513.BBNG_00455	2.7e-120	438.0	Bifidobacteriales	rsmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	2.1.1.172	ko:K00564			R07234	RC00003	ko00000,ko01000,ko03009				Bacteria	2IFG7@201174,4CZP1@85004,COG2813@1,COG2813@2	NA|NA|NA	J	Ribosomal protein L11 methyltransferase (PrmA)
NIOIMGPL_00407	398513.BBNG_00456	1.2e-171	609.0	Bifidobacteriales													Bacteria	29PMQ@1,2I95H@201174,30AJW@2,4D0N6@85004	NA|NA|NA		
NIOIMGPL_00408	398513.BBNG_00457	3.1e-273	947.2	Bifidobacteriales	hflX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464		ko:K03665					ko00000,ko03009				Bacteria	2GK55@201174,4CZCB@85004,COG2262@1,COG2262@2	NA|NA|NA	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NIOIMGPL_00409	398513.BBNG_00458	4.6e-177	627.1	Bifidobacteriales	ldh		1.1.1.27,1.1.1.37	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R00703,R01000,R03104,R07136	RC00031,RC00044	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	2GN5S@201174,4CYWK@85004,COG0039@1,COG0039@2	NA|NA|NA	C	Belongs to the LDH MDH superfamily. LDH family
NIOIMGPL_00410	398513.BBNG_00459	2.3e-165	588.2	Bifidobacteriales	czcD			ko:K16264					ko00000,ko02000	2.A.4.1			Bacteria	2GMRZ@201174,4CZAB@85004,COG1230@1,COG1230@2	NA|NA|NA	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NIOIMGPL_00411	398513.BBNG_00460	7.5e-129	466.5	Bifidobacteriales	lexA		3.4.21.88	ko:K01356		M00729			ko00000,ko00002,ko01000,ko01002,ko03400				Bacteria	2GMBN@201174,4CZ26@85004,COG1974@1,COG1974@2	NA|NA|NA	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NIOIMGPL_00412	702459.BBPR_0543	6.1e-45	186.4	Bifidobacteriales													Bacteria	2HVH4@201174,4D1G8@85004,COG1388@1,COG1388@2	NA|NA|NA	M	Lysin motif
NIOIMGPL_00413	702459.BBPR_0544	8.8e-83	313.2	Bifidobacteriales	nrdR	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141		ko:K07738					ko00000,ko03000				Bacteria	2IHU9@201174,4D0P7@85004,COG1327@1,COG1327@2	NA|NA|NA	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NIOIMGPL_00414	398513.BBNG_00463	1.7e-210	738.4	Bifidobacteriales	serA	GO:0003674,GO:0003824,GO:0004617,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008219,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0012501,GO:0016053,GO:0016491,GO:0016597,GO:0016614,GO:0016616,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047545,GO:0055114,GO:0070905,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147			iYL1228.KPN_03348	Bacteria	2GJGA@201174,4CYPT@85004,COG0111@1,COG0111@2	NA|NA|NA	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NIOIMGPL_00415	702459.BBPR_0546	0.0	1471.1	Bifidobacteriales													Bacteria	2GK30@201174,4CYUF@85004,COG3973@1,COG3973@2	NA|NA|NA	L	DNA helicase
NIOIMGPL_00416	398513.BBNG_00465	1.3e-90	339.0	Bifidobacteriales	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141		ko:K03925					ko00000				Bacteria	2IHUB@201174,4D0P1@85004,COG2001@1,COG2001@2	NA|NA|NA	K	Belongs to the MraZ family
NIOIMGPL_00417	398513.BBNG_00466	7.8e-189	666.4	Bifidobacteriales	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438					ko00000,ko01000,ko03009				Bacteria	2GJGK@201174,4CYRM@85004,COG0275@1,COG0275@2	NA|NA|NA	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NIOIMGPL_00418	702459.BBPR_0549	4.1e-62	244.2	Bifidobacteriales	ftsL			ko:K05589,ko:K12065					ko00000,ko02044,ko03036	3.A.7.11.1			Bacteria	2IKUA@201174,4D109@85004,COG2919@1,COG2919@2	NA|NA|NA	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NIOIMGPL_00419	702459.BBPR_0550	0.0	1165.2	Bifidobacteriales	ftsI	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681	3.4.16.4	ko:K03587,ko:K08384,ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501				ko00000,ko00001,ko01000,ko01011,ko03036			iSSON_1240.SSON_0092	Bacteria	2GKHH@201174,4CYS8@85004,COG0768@1,COG0768@2	NA|NA|NA	M	Penicillin-binding protein, transpeptidase domain protein
NIOIMGPL_00420	702459.BBPR_0551	2.8e-180	637.9	Bifidobacteriales	yqeC		6.3.2.10,6.3.2.13	ko:K01928,ko:K15792	ko00300,ko00550,map00300,map00550		R02788,R04617	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01011				Bacteria	2GMZF@201174,4CYWT@85004,COG0769@1,COG0769@2	NA|NA|NA	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NIOIMGPL_00421	702459.BBPR_0552	3.2e-281	973.8	Bifidobacteriales	murF		6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502		R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011				Bacteria	2GK0Y@201174,4CZ7U@85004,COG0770@1,COG0770@2	NA|NA|NA	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NIOIMGPL_00422	702459.BBPR_0553	3.6e-202	710.7	Bifidobacteriales	mraY	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502		R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146		iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105	Bacteria	2GNEH@201174,4CYRX@85004,COG0472@1,COG0472@2	NA|NA|NA	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NIOIMGPL_00423	702459.BBPR_0554	5.5e-245	853.2	Bifidobacteriales	murD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100		R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011			iNJ661.Rv2155c	Bacteria	2GJZA@201174,4CZKI@85004,COG0771@1,COG0771@2	NA|NA|NA	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NIOIMGPL_00424	702459.BBPR_0555	9e-224	782.7	Bifidobacteriales	ftsW	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008360,GO:0009987,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032153,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505	2.4.1.227	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112		R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	2.A.103.1	GT28		Bacteria	2GKXP@201174,4CYPZ@85004,COG0772@1,COG0772@2	NA|NA|NA	D	Belongs to the SEDS family
NIOIMGPL_00425	398513.BBNG_00473	6.5e-218	763.1	Bifidobacteriales	murG	GO:0008150,GO:0040007	2.4.1.227,6.3.2.8	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112		R03193,R05032,R05662	RC00005,RC00049,RC00064,RC00141	ko00000,ko00001,ko01000,ko01011		GT28	iLJ478.TM0232	Bacteria	2GJEM@201174,4CYQS@85004,COG0707@1,COG0707@2	NA|NA|NA	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NIOIMGPL_00426	398513.BBNG_00474	2.9e-293	1013.8	Bifidobacteriales	murC	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100		R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011				Bacteria	2I2E7@201174,4CZ3B@85004,COG0773@1,COG0773@2	NA|NA|NA	M	Belongs to the MurCDEF family
NIOIMGPL_00427	702459.BBPR_0558	4.7e-158	564.3	Bifidobacteriales	ftsQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	6.3.2.4	ko:K01921,ko:K03589,ko:K06438	ko00473,ko00550,ko01100,ko01502,ko04112,map00473,map00550,map01100,map01502,map04112		R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011,ko03036				Bacteria	2H4A4@201174,4D04A@85004,COG1589@1,COG1589@2	NA|NA|NA	D	Cell division protein FtsQ
NIOIMGPL_00428	398513.BBNG_00476	4.9e-37	160.6	Bifidobacteriales													Bacteria	2B3SJ@1,2GX7W@201174,31WG6@2,4D1T0@85004	NA|NA|NA		
NIOIMGPL_00430	398513.BBNG_00478	2.6e-85	321.2	Bifidobacteriales	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360		ko:K07560					ko00000,ko01000,ko03016				Bacteria	2IKVR@201174,4D0VE@85004,COG1490@1,COG1490@2	NA|NA|NA	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NIOIMGPL_00431	702459.BBPR_0561	1.3e-235	822.0	Bifidobacteriales													Bacteria	2I966@201174,4CZRX@85004,COG0738@1,COG0738@2	NA|NA|NA	G	Major Facilitator Superfamily
NIOIMGPL_00432	398513.BBNG_00480	5.6e-169	600.1	Bifidobacteriales			2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100		R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000				Bacteria	2HZB3@201174,4CZFC@85004,COG0524@1,COG0524@2	NA|NA|NA	G	pfkB family carbohydrate kinase
NIOIMGPL_00433	398513.BBNG_00481	1.3e-224	785.4	Bifidobacteriales													Bacteria	2GJ2S@201174,4CYV9@85004,COG1940@1,COG1940@2	NA|NA|NA	GK	ROK family
NIOIMGPL_00434	702459.BBPR_0564	2.2e-131	474.9	Bifidobacteriales	cutC			ko:K06201					ko00000				Bacteria	2GKI8@201174,4D054@85004,COG3142@1,COG3142@2	NA|NA|NA	P	Participates in the control of copper homeostasis
NIOIMGPL_00435	398513.BBNG_00483	4.1e-173	614.0	Bifidobacteriales													Bacteria	2GKMZ@201174,4CZUF@85004,COG1940@1,COG1940@2	NA|NA|NA	GK	ROK family
NIOIMGPL_00436	398513.BBNG_00484	4e-150	537.3	Bifidobacteriales	nagB		3.1.1.31,3.5.99.6	ko:K01057,ko:K02564	ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R00765,R02035	RC00163,RC00537	ko00000,ko00001,ko00002,ko01000				Bacteria	2GK7F@201174,4CYYE@85004,COG0363@1,COG0363@2	NA|NA|NA	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NIOIMGPL_00437	702459.BBPR_0567	6.2e-243	846.3	Bifidobacteriales	nagA		3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130		R02059	RC00166,RC00300	ko00000,ko00001,ko01000				Bacteria	2GK1E@201174,4CZKB@85004,COG1820@1,COG1820@2	NA|NA|NA	G	Amidohydrolase family
NIOIMGPL_00438	398513.BBNG_01486	0.0	1083.9	Bifidobacteriales	yegQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464		ko:K08303	ko05120,map05120				ko00000,ko00001,ko01000,ko01002				Bacteria	2GKTB@201174,4CZA1@85004,COG0826@1,COG0826@2	NA|NA|NA	O	Peptidase family U32 C-terminal domain
NIOIMGPL_00439	702459.BBPR_1617	8.7e-187	659.4	Bifidobacteriales	yfiH	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0030312,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114,GO:0071944		ko:K05810					ko00000,ko01000				Bacteria	2GN1M@201174,4CZBI@85004,COG1496@1,COG1496@2	NA|NA|NA	Q	Multi-copper polyphenol oxidoreductase laccase
NIOIMGPL_00440	398513.BBNG_01488	6.5e-145	520.0	Bifidobacteriales	ispD	GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.405,2.7.7.40,2.7.7.60,4.6.1.12	ko:K00991,ko:K12506,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	M00096	R01525,R02921,R05633,R05637	RC00002,RC00089,RC01440	ko00000,ko00001,ko00002,ko01000				Bacteria	2GNHP@201174,4CYVZ@85004,COG1211@1,COG1211@2	NA|NA|NA	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NIOIMGPL_00441	398513.BBNG_01489	8e-128	463.0	Bifidobacteriales	pcp	GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564	3.4.19.3	ko:K01304					ko00000,ko01000,ko01002				Bacteria	2GN39@201174,4CZ57@85004,COG2039@1,COG2039@2	NA|NA|NA	O	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NIOIMGPL_00442	398513.BBNG_01490	3.3e-41	176.4	Bifidobacteriales													Bacteria	2HZ99@201174,4CZ0S@85004,COG1196@1,COG1196@2	NA|NA|NA	D	nuclear chromosome segregation
NIOIMGPL_00443	702459.BBPR_1612	7.1e-269	932.6	Bifidobacteriales	pepC	GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.4.22.40	ko:K01372					ko00000,ko01000,ko01002				Bacteria	2GNYU@201174,4CZDZ@85004,COG3579@1,COG3579@2	NA|NA|NA	E	Peptidase C1-like family
NIOIMGPL_00444	702459.BBPR_1611	7.8e-167	593.2	Bifidobacteriales				ko:K03646					ko00000,ko02000	2.C.1.2			Bacteria	2GJ38@201174,4CYVR@85004,COG2356@1,COG2356@2,COG3064@1,COG3064@2	NA|NA|NA	L	Excalibur calcium-binding domain
NIOIMGPL_00445	702459.BBPR_1610	1.5e-219	768.5	Bifidobacteriales	aroG	GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_2375,iAPECO1_1312.APECO1_3932,iECNA114_1301.ECNA114_0684,iECOK1_1307.ECOK1_2946,iECS88_1305.ECS88_2787,iECSF_1327.ECSF_0680,iEcSMS35_1347.EcSMS35_0777,iHN637.CLJU_RS07240,iLF82_1304.LF82_0146,iNRG857_1313.NRG857_03335,iSbBS512_1146.SbBS512_E1908,iUMN146_1321.UM146_03705,iUTI89_1310.UTI89_C2934,iYL1228.KPN_00758	Bacteria	2GMVF@201174,4CZMR@85004,COG0722@1,COG0722@2	NA|NA|NA	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NIOIMGPL_00446	398513.BBNG_01494	1.8e-243	848.2	Bifidobacteriales													Bacteria	2I8QF@201174,4CZF1@85004,COG0477@1,COG2814@2	NA|NA|NA	EGP	Major facilitator Superfamily
NIOIMGPL_00447	398513.BBNG_01495	9.7e-109	399.4	Bifidobacteriales				ko:K04096					ko00000				Bacteria	2II9U@201174,4D0Y5@85004,COG0640@1,COG0640@2	NA|NA|NA	K	helix_turn_helix, Arsenical Resistance Operon Repressor
NIOIMGPL_00448	398513.BBNG_01496	8.3e-240	835.9	Bifidobacteriales	aroG	GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_2375,iAPECO1_1312.APECO1_3932,iECNA114_1301.ECNA114_0684,iECOK1_1307.ECOK1_2946,iECS88_1305.ECS88_2787,iECSF_1327.ECSF_0680,iEcSMS35_1347.EcSMS35_0777,iHN637.CLJU_RS07240,iLF82_1304.LF82_0146,iNRG857_1313.NRG857_03335,iSbBS512_1146.SbBS512_E1908,iUMN146_1321.UM146_03705,iUTI89_1310.UTI89_C2934,iYL1228.KPN_00758	Bacteria	2GMVF@201174,4CZ7I@85004,COG0722@1,COG0722@2	NA|NA|NA	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NIOIMGPL_00449	398513.BBNG_01497	4.3e-124	450.7	Bifidobacteriales	mtnN		3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000				Bacteria	2I8GZ@201174,4CYTM@85004,COG0775@1,COG0775@2	NA|NA|NA	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NIOIMGPL_00450	702459.BBPR_1605	1.7e-241	841.6	Bifidobacteriales	senX3	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564	2.7.13.3	ko:K07636,ko:K07768,ko:K11383	ko02020,map02020	M00434,M00443,M00505			ko00000,ko00001,ko00002,ko01000,ko01001,ko02022				Bacteria	2GJY7@201174,4CZ42@85004,COG5002@1,COG5002@2	NA|NA|NA	T	His Kinase A (phosphoacceptor) domain
NIOIMGPL_00451	398513.BBNG_01499	1.3e-128	465.7	Bifidobacteriales													Bacteria	2GKFS@201174,4CZTX@85004,COG0745@1,COG0745@2	NA|NA|NA	KT	Transcriptional regulatory protein, C terminal
NIOIMGPL_00452	398513.BBNG_01500	2.3e-172	611.7	Bifidobacteriales	pstS			ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222			ko00000,ko00001,ko00002,ko02000	3.A.1.7			Bacteria	2GJXD@201174,4CYTZ@85004,COG0226@1,COG0226@2	NA|NA|NA	P	Part of the ABC transporter complex PstSACB involved in phosphate import
NIOIMGPL_00453	398513.BBNG_01501	3.8e-171	607.4	Bifidobacteriales	pstC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0009314,GO:0009628,GO:0010921,GO:0015698,GO:0016020,GO:0016021,GO:0019220,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0034220,GO:0035303,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0098656,GO:0098660,GO:0098661		ko:K02037,ko:K02038	ko02010,map02010	M00222			ko00000,ko00001,ko00002,ko02000	3.A.1.7		iAF987.Gmet_2702,ic_1306.c4652	Bacteria	2GJDA@201174,4CYV0@85004,COG0573@1,COG0573@2	NA|NA|NA	P	probably responsible for the translocation of the substrate across the membrane
NIOIMGPL_00454	702459.BBPR_1601	6.2e-180	636.7	Bifidobacteriales	pstA	GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0010921,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0019220,GO:0019222,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0031323,GO:0033554,GO:0034220,GO:0035303,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0098656,GO:0098660,GO:0098661		ko:K02037,ko:K02038	ko02010,map02010	M00222			ko00000,ko00001,ko00002,ko02000	3.A.1.7		iJN746.PP_2658,iPC815.YPO4115,iYL1228.KPN_04131,iZ_1308.Z5217	Bacteria	2I2F2@201174,4D2UW@85004,COG0581@1,COG0581@2	NA|NA|NA	P	Phosphate transport system permease
NIOIMGPL_00455	398513.BBNG_01503	3.6e-148	530.8	Bifidobacteriales	pstB		3.6.3.27	ko:K02036	ko02010,map02010	M00222			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7			Bacteria	2GJQ3@201174,4CYVE@85004,COG1117@1,COG1117@2	NA|NA|NA	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NIOIMGPL_00456	702459.BBPR_1599	1.7e-168	598.6	Bifidobacteriales	gmk		1.1.1.23,2.7.4.8	ko:K00013,ko:K00942	ko00230,ko00340,ko01100,ko01110,ko01230,map00230,map00340,map01100,map01110,map01230	M00026,M00050	R00332,R01158,R01163,R02090,R03012	RC00002,RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000				Bacteria	2HTNX@201174,4D0CP@85004,COG2852@1,COG2852@2	NA|NA|NA	S	Protein conserved in bacteria
NIOIMGPL_00457	398513.BBNG_01504	1.4e-12	77.4	Bifidobacteriales	gmk		1.1.1.23,2.7.4.8	ko:K00013,ko:K00942	ko00230,ko00340,ko01100,ko01110,ko01230,map00230,map00340,map01100,map01110,map01230	M00026,M00050	R00332,R01158,R01163,R02090,R03012	RC00002,RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000				Bacteria	2HTNX@201174,4D0CP@85004,COG2852@1,COG2852@2	NA|NA|NA	S	Protein conserved in bacteria
NIOIMGPL_00458	398513.BBNG_01505	8.8e-222	776.2	Bifidobacteriales	pbuO			ko:K06901					ko00000,ko02000	2.A.1.40			Bacteria	2GKYD@201174,4CZHD@85004,COG2252@1,COG2252@2	NA|NA|NA	S	Permease family
NIOIMGPL_00460	398513.BBNG_01507	1e-207	729.2	Actinobacteria	guxA1		3.2.1.18,3.2.1.91	ko:K01186,ko:K19668	ko00500,ko00511,ko00600,ko01100,ko02020,ko04142,map00500,map00511,map00600,map01100,map02020,map04142		R02886,R04018,R11308	RC00028,RC00077,RC00799	ko00000,ko00001,ko01000,ko02042		GH33,GH6		Bacteria	2GUR0@201174,COG3934@1,COG3934@2,COG4409@1,COG4409@2,COG5492@1,COG5492@2	NA|NA|NA	G	BNR repeat-like domain
NIOIMGPL_00461	398513.BBNG_01507	0.0	2591.6	Actinobacteria	guxA1		3.2.1.18,3.2.1.91	ko:K01186,ko:K19668	ko00500,ko00511,ko00600,ko01100,ko02020,ko04142,map00500,map00511,map00600,map01100,map02020,map04142		R02886,R04018,R11308	RC00028,RC00077,RC00799	ko00000,ko00001,ko01000,ko02042		GH33,GH6		Bacteria	2GUR0@201174,COG3934@1,COG3934@2,COG4409@1,COG4409@2,COG5492@1,COG5492@2	NA|NA|NA	G	BNR repeat-like domain
NIOIMGPL_00462	398513.BBNG_01508	2.2e-130	472.2	Bacteria	xynB2		1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000				Bacteria	COG2755@1,COG2755@2	NA|NA|NA	E	lipolytic protein G-D-S-L family
NIOIMGPL_00463	398513.BBNG_01509	2.1e-88	331.6	Bifidobacteriales	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113		ko:K02864,ko:K02935	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	2GM0V@201174,4CZFP@85004,COG0244@1,COG0244@2	NA|NA|NA	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NIOIMGPL_00464	1437610.BREU_0570	1.3e-37	162.5	Bifidobacteriales	rplL	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944		ko:K02935	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	2IKNW@201174,4D0W2@85004,COG0222@1,COG0222@2	NA|NA|NA	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NIOIMGPL_00466	702459.BBPR_1592	5.2e-245	853.6	Bifidobacteriales													Bacteria	2GIT6@201174,4CYX9@85004,COG1716@1,COG1716@2	NA|NA|NA	T	Forkhead associated domain
NIOIMGPL_00467	702459.BBPR_1591	0.0	2335.1	Bifidobacteriales													Bacteria	2GKJW@201174,4CYY9@85004,COG1112@1,COG1112@2	NA|NA|NA	L	Superfamily I DNA and RNA helicases and helicase subunits
NIOIMGPL_00468	702459.BBPR_1590	9.6e-42	175.6	Bifidobacteriales													Bacteria	2B18D@1,2GSR6@201174,31TNU@2,4D1ET@85004	NA|NA|NA		
NIOIMGPL_00469	398513.BBNG_01514	3.6e-109	401.0	Bifidobacteriales	flgA	GO:0001539,GO:0006928,GO:0008150,GO:0009987,GO:0040011,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588		ko:K02279,ko:K02386	ko02040,map02040				ko00000,ko00001,ko02035,ko02044				Bacteria	2IIYF@201174,4D0YD@85004,COG1261@1,COG1261@2	NA|NA|NA	NO	SAF
NIOIMGPL_00470	398513.BBNG_01515	3.2e-38	163.7	Bifidobacteriales	fmdB												Bacteria	2IQHE@201174,4D1ES@85004,COG2331@1,COG2331@2	NA|NA|NA	S	Putative regulatory protein
NIOIMGPL_00471	398513.BBNG_01516	1.8e-121	441.8	Bifidobacteriales	fthC		6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100		R02301	RC00183	ko00000,ko00001,ko01000				Bacteria	2IKWR@201174,4D12B@85004,COG0212@1,COG0212@2	NA|NA|NA	H	5-formyltetrahydrofolate cyclo-ligase family
NIOIMGPL_00472	702459.BBPR_1586	3.2e-149	534.3	Bifidobacteriales	rimJ		2.3.1.128	ko:K03790					ko00000,ko01000,ko03009				Bacteria	2HAFI@201174,4CZRR@85004,COG1670@1,COG1670@2	NA|NA|NA	J	Acetyltransferase (GNAT) domain
NIOIMGPL_00473	78345.BMERY_0231	1.5e-111	409.1	Bifidobacteriales													Bacteria	2GU5Z@201174,4D0KF@85004,COG1002@1,COG1002@2	NA|NA|NA	V	Type II restriction enzyme, methylase
NIOIMGPL_00474	78345.BMERY_0231	5.1e-44	183.3	Bifidobacteriales													Bacteria	2GU5Z@201174,4D0KF@85004,COG1002@1,COG1002@2	NA|NA|NA	V	Type II restriction enzyme, methylase
NIOIMGPL_00475	78345.BMERY_0231	4.2e-95	354.0	Bifidobacteriales													Bacteria	2GU5Z@201174,4D0KF@85004,COG1002@1,COG1002@2	NA|NA|NA	V	Type II restriction enzyme, methylase
NIOIMGPL_00476	78345.BMERY_0230	6.1e-25	119.4	Bifidobacteriales	hepA												Bacteria	2GM2V@201174,4D0U5@85004,COG0553@1,COG0553@2	NA|NA|NA	L	SNF2 family N-terminal domain
NIOIMGPL_00477	78345.BMERY_0230	1.1e-95	355.9	Bifidobacteriales	hepA												Bacteria	2GM2V@201174,4D0U5@85004,COG0553@1,COG0553@2	NA|NA|NA	L	SNF2 family N-terminal domain
NIOIMGPL_00478	398513.BBNG_01170	1.7e-68	265.0	Bifidobacteriales													Bacteria	2B93G@1,2H6SR@201174,322EB@2,4D2AZ@85004	NA|NA|NA		
NIOIMGPL_00479	547043.BIFPSEUDO_02914	9.7e-115	419.9	Bifidobacteriales	ppiA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030312,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0140096,GO:1901564	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217				ko00000,ko00001,ko01000,ko03110,ko04147				Bacteria	2IFUE@201174,4CZSU@85004,COG0652@1,COG0652@2	NA|NA|NA	G	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NIOIMGPL_00480	702459.BBPR_1240	1.2e-165	589.0	Bifidobacteriales													Bacteria	2HZBH@201174,4CZIQ@85004,COG0561@1,COG0561@2	NA|NA|NA	S	Sucrose-6F-phosphate phosphohydrolase
NIOIMGPL_00481	398513.BBNG_01166	2.1e-94	351.7	Bacteria													Bacteria	COG2011@1,COG2011@2	NA|NA|NA	P	ABC-type metal ion transport system permease component
NIOIMGPL_00482	702459.BBPR_1238	1.7e-223	781.6	Bifidobacteriales				ko:K01436					ko00000,ko01000,ko01002				Bacteria	2GK05@201174,4CZC6@85004,COG1473@1,COG1473@2	NA|NA|NA	S	Peptidase dimerisation domain
NIOIMGPL_00483	398513.BBNG_01164	0.0	1151.0	Bifidobacteriales	nadE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000				Bacteria	2GK2C@201174,4CZ14@85004,COG0171@1,COG0171@2,COG0388@1,COG0388@2	NA|NA|NA	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NIOIMGPL_00484	702459.BBPR_1236	6.4e-40	169.5	Bifidobacteriales													Bacteria	2EHMB@1,2HZRX@201174,33BD3@2,4D1G1@85004	NA|NA|NA		
NIOIMGPL_00485	702459.BBPR_1235	0.0	1629.4	Bifidobacteriales	pflB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006629,GO:0006631,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016020,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017144,GO:0019541,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0043875,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0070689,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120		R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000			iECH74115_1262.ECH74115_1064,iECIAI39_1322.ECIAI39_2245,iECSP_1301.ECSP_1007,iECs_1301.ECs0986,iEcSMS35_1347.EcSMS35_2218,iEcSMS35_1347.EcSMS35_3410,iG2583_1286.G2583_1138,iSDY_1059.SDY_2358,iZ_1308.Z1248	Bacteria	2GTTT@201174,4CZ59@85004,COG1882@1,COG1882@2	NA|NA|NA	C	Pyruvate formate lyase-like
NIOIMGPL_00486	398513.BBNG_01161	3.9e-175	620.5	Bifidobacteriales	pflA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0018307,GO:0019538,GO:0033554,GO:0036211,GO:0043170,GO:0043364,GO:0043365,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070283,GO:0071704,GO:1901564	1.97.1.4	ko:K04069			R04710		ko00000,ko01000			iECOK1_1307.ECOK1_0925,iEcE24377_1341.EcE24377A_0980,iEcSMS35_1347.EcSMS35_2219,iYL1228.KPN_00930	Bacteria	2GN2B@201174,4CZ5Y@85004,COG1180@1,COG1180@2	NA|NA|NA	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NIOIMGPL_00487	702459.BBPR_1233	4.4e-114	417.2	Bifidobacteriales													Bacteria	2B58P@1,2HZMM@201174,31Y2Q@2,4D0Y9@85004	NA|NA|NA	S	Protein of unknown function (DUF3000)
NIOIMGPL_00488	702459.BBPR_1232	7e-250	869.4	Bifidobacteriales	rnd		3.1.13.5	ko:K03684					ko00000,ko01000,ko03016				Bacteria	2GKNM@201174,4CYUV@85004,COG0349@1,COG0349@2	NA|NA|NA	J	3'-5' exonuclease
NIOIMGPL_00489	398513.BBNG_01158	2.8e-236	824.3	Bifidobacteriales	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944		ko:K03545					ko00000				Bacteria	2GJIG@201174,4CZ6P@85004,COG0544@1,COG0544@2	NA|NA|NA	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NIOIMGPL_00490	398513.BBNG_01157	1.9e-54	218.4	Bifidobacteriales	clcA_2			ko:K03281					ko00000	2.A.49			Bacteria	2GPPN@201174,4CZPX@85004,COG0038@1,COG0038@2	NA|NA|NA	P	Voltage gated chloride channel
NIOIMGPL_00491	398513.BBNG_01157	6.9e-176	623.2	Bifidobacteriales	clcA_2			ko:K03281					ko00000	2.A.49			Bacteria	2GPPN@201174,4CZPX@85004,COG0038@1,COG0038@2	NA|NA|NA	P	Voltage gated chloride channel
NIOIMGPL_00493	398513.BBNG_01156	1.1e-112	412.5	Bifidobacteriales	clpP		3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212				ko00000,ko00001,ko01000,ko01002				Bacteria	2GK5C@201174,4CYUU@85004,COG0740@1,COG0740@2	NA|NA|NA	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NIOIMGPL_00494	702459.BBPR_1228	1.5e-23	115.2	Bifidobacteriales	clpP	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212				ko00000,ko00001,ko01000,ko01002				Bacteria	2GKNK@201174,4CZVF@85004,COG0740@1,COG0740@2	NA|NA|NA	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NIOIMGPL_00495	398513.BBNG_01155	3.3e-77	294.3	Bifidobacteriales	clpP	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212				ko00000,ko00001,ko01000,ko01002				Bacteria	2GKNK@201174,4CZVF@85004,COG0740@1,COG0740@2	NA|NA|NA	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NIOIMGPL_00496	702459.BBPR_1227	1e-243	849.0	Bifidobacteriales	clpX	GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369		ko:K03544	ko04112,map04112				ko00000,ko00001,ko03110				Bacteria	2GJXQ@201174,4CYT6@85004,COG1219@1,COG1219@2	NA|NA|NA	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NIOIMGPL_00499	702459.BBPR_1226	1.9e-233	814.7	Bifidobacteriales	patB		4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230		R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007				Bacteria	2GJFQ@201174,4CZFH@85004,COG1168@1,COG1168@2	NA|NA|NA	E	Aminotransferase, class I II
NIOIMGPL_00500	702459.BBPR_1225	1.6e-225	788.5	Bifidobacteriales	nhaA			ko:K03313					ko00000,ko02000	2.A.33.1			Bacteria	2GKIK@201174,4CZES@85004,COG3004@1,COG3004@2	NA|NA|NA	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NIOIMGPL_00501	398513.BBNG_01151	1.8e-165	588.6	Bifidobacteriales	fmt2		3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240		R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000				Bacteria	2GKJH@201174,4CZ8R@85004,COG1611@1,COG1611@2	NA|NA|NA	S	Belongs to the LOG family
NIOIMGPL_00502	398513.BBNG_01150	5.7e-118	430.3	Bifidobacteriales	safC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944											Bacteria	2HXV7@201174,4CZZN@85004,COG4122@1,COG4122@2	NA|NA|NA	S	O-methyltransferase
NIOIMGPL_00503	398513.BBNG_01149	6.6e-184	649.8	Bifidobacteriales	sdhB	GO:0000104,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0022904,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000			e_coli_core.b0724,iAF1260.b0724,iBWG_1329.BWG_0583,iEC042_1314.EC042_0742,iECDH10B_1368.ECDH10B_0791,iECDH1ME8569_1439.ECDH1ME8569_0683,iECUMN_1333.ECUMN_0802,iEcDH1_1363.EcDH1_2911,iJO1366.b0724,iJR904.b0724,iY75_1357.Y75_RS03765	Bacteria	2GP9C@201174,4CZWJ@85004,COG0479@1,COG0479@2	NA|NA|NA	C	4Fe-4S dicluster domain
NIOIMGPL_00504	398513.BBNG_01148	3e-71	274.2	Bifidobacteriales	yraN			ko:K07460					ko00000				Bacteria	2IQ3X@201174,4D191@85004,COG0792@1,COG0792@2	NA|NA|NA	L	Belongs to the UPF0102 family
NIOIMGPL_00505	398513.BBNG_01147	1.9e-294	1017.7	Bifidobacteriales	comM			ko:K07391					ko00000				Bacteria	2GJIQ@201174,4CYUB@85004,COG0606@1,COG0606@2	NA|NA|NA	O	Magnesium chelatase, subunit ChlI C-terminal
NIOIMGPL_00506	702459.BBPR_1219	6.7e-284	982.6	Bifidobacteriales	dprA		5.99.1.2	ko:K03168,ko:K04096					ko00000,ko01000,ko03032,ko03400				Bacteria	2GKDA@201174,4CYVW@85004,COG0758@1,COG0758@2	NA|NA|NA	LU	DNA recombination-mediator protein A
NIOIMGPL_00507	398513.BBNG_01145	1.3e-57	229.2	Bifidobacteriales	ybaZ	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363	2.1.1.63	ko:K00567,ko:K07443					ko00000,ko01000,ko03400				Bacteria	2I2IB@201174,4D2W1@85004,COG3695@1,COG3695@2	NA|NA|NA	L	6-O-methylguanine DNA methyltransferase, DNA binding domain
NIOIMGPL_00508	702459.BBPR_1217	0.0	1302.7	Bifidobacteriales	sdhA	GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071704,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0072350,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000			iE2348C_1286.E2348C_0603,iJN746.PP_4191,iPC815.YPO1111	Bacteria	2GJ45@201174,4CYT5@85004,COG1053@1,COG1053@2	NA|NA|NA	C	Succinate dehydrogenase flavoprotein subunit
NIOIMGPL_00509	398513.BBNG_01143	1.3e-90	339.0	Bifidobacteriales	pdxK		2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100		R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000				Bacteria	2HS59@201174,4CYQC@85004,COG2240@1,COG2240@2	NA|NA|NA	H	Phosphomethylpyrimidine kinase
NIOIMGPL_00510	398513.BBNG_01141	3.9e-142	510.8	Bifidobacteriales													Bacteria	2IGJG@201174,4D0SP@85004,COG4905@1,COG4905@2	NA|NA|NA	S	Putative ABC-transporter type IV
NIOIMGPL_00511	702459.BBPR_1213	5e-251	873.2	Bifidobacteriales	metY		2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100		R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000				Bacteria	2I2EB@201174,4CZCT@85004,COG2873@1,COG2873@2	NA|NA|NA	E	Aminotransferase class-V
NIOIMGPL_00512	398513.BBNG_01139	8.9e-163	579.7	Bifidobacteriales				ko:K02003		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	2GJN6@201174,4CZ04@85004,COG1136@1,COG1136@2	NA|NA|NA	V	ABC transporter, ATP-binding protein
NIOIMGPL_00513	702459.BBPR_1211	4e-216	757.3	Bifidobacteriales				ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	2GJTZ@201174,4CZUR@85004,COG0577@1,COG0577@2,COG4591@1,COG4591@2	NA|NA|NA	MV	MacB-like periplasmic core domain
NIOIMGPL_00514	398513.BBNG_01138	6.4e-217	760.0	Bifidobacteriales				ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	2GJTZ@201174,4CZUR@85004,COG0577@1,COG0577@2,COG4591@1,COG4591@2	NA|NA|NA	MV	MacB-like periplasmic core domain
NIOIMGPL_00515	702459.BBPR_1210	0.0	1791.2	Bifidobacteriales	phoN												Bacteria	2I4ZG@201174,4CZ80@85004,COG0671@1,COG0671@2	NA|NA|NA	I	PAP2 superfamily
NIOIMGPL_00516	398513.BBNG_01136	2.5e-49	201.1	Bifidobacteriales													Bacteria	2GJ46@201174,4CYQW@85004,COG2197@1,COG2197@2	NA|NA|NA	K	helix_turn_helix, Lux Regulon
NIOIMGPL_00517	398513.BBNG_01136	5.5e-31	140.6	Bifidobacteriales													Bacteria	2GJ46@201174,4CYQW@85004,COG2197@1,COG2197@2	NA|NA|NA	K	helix_turn_helix, Lux Regulon
NIOIMGPL_00518	398513.BBNG_01135	0.0	1398.6	Bifidobacteriales	tcsS2												Bacteria	2GJEG@201174,4CZ1M@85004,COG4585@1,COG4585@2	NA|NA|NA	T	Histidine kinase
NIOIMGPL_00519	702459.BBPR_1206	3.6e-263	913.7	Bifidobacteriales	pip		3.4.11.5	ko:K01259	ko00330,map00330		R00135		ko00000,ko00001,ko01000,ko01002				Bacteria	2GK03@201174,4CZ9T@85004,COG0596@1,COG0596@2	NA|NA|NA	S	alpha/beta hydrolase fold
NIOIMGPL_00520	702459.BBPR_1205	7.2e-144	516.5	Bifidobacteriales	proC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_0899,iIT341.HP1158	Bacteria	2GJ7D@201174,4CZIV@85004,COG0345@1,COG0345@2	NA|NA|NA	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NIOIMGPL_00521	398513.BBNG_01132	1.9e-167	595.1	Bifidobacteriales	iaaA		3.4.19.5,3.5.1.1	ko:K01424,ko:K13051	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110		R00485	RC00010,RC02798	ko00000,ko00001,ko01000,ko01002				Bacteria	2IDMF@201174,4D073@85004,COG1446@1,COG1446@2	NA|NA|NA	E	Asparaginase
NIOIMGPL_00522	398513.BBNG_01130	1.6e-146	525.4	Bifidobacteriales				ko:K02073	ko02010,map02010	M00238			ko00000,ko00001,ko00002,ko02000	3.A.1.24			Bacteria	2GMNI@201174,4CZNB@85004,COG1464@1,COG1464@2	NA|NA|NA	P	NLPA lipoprotein
NIOIMGPL_00523	398513.BBNG_01129	1.9e-186	658.3	Actinobacteria	acoA		1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	2I3T8@201174,COG1071@1,COG1071@2	NA|NA|NA	C	Dehydrogenase E1 component
NIOIMGPL_00524	702459.BBPR_1200	3.9e-182	644.0	Actinobacteria			1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	2GKFE@201174,COG0022@1,COG0022@2	NA|NA|NA	C	Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
NIOIMGPL_00525	702459.BBPR_1199	3e-204	717.6	Bifidobacteriales	metN			ko:K02071	ko02010,map02010	M00238			ko00000,ko00001,ko00002,ko02000	3.A.1.24			Bacteria	2GJ9P@201174,4CZYI@85004,COG1135@1,COG1135@2	NA|NA|NA	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NIOIMGPL_00526	702459.BBPR_1198	2.9e-93	348.2	Bifidobacteriales	metI			ko:K02072	ko02010,map02010	M00238			ko00000,ko00001,ko00002,ko02000	3.A.1.24			Bacteria	2GY65@201174,4CZWG@85004,COG2011@1,COG2011@2	NA|NA|NA	P	Binding-protein-dependent transport system inner membrane component
NIOIMGPL_00527	702459.BBPR_1197	4.9e-229	800.0	Bifidobacteriales	mtnE	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009987,GO:0016740,GO:0016769,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249	2.6.1.83	ko:K08969,ko:K10206,ko:K19549	ko00270,ko00300,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map01100,map01110,map01130,map01230	M00034,M00527,M00787	R07396,R07613,R11068	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	2GJ7R@201174,4CZCF@85004,COG0436@1,COG0436@2	NA|NA|NA	E	Aminotransferase class I and II
NIOIMGPL_00528	398513.BBNG_01125	1.4e-201	708.8	Bifidobacteriales	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464		ko:K06942					ko00000,ko03009				Bacteria	2GIXI@201174,4CZBU@85004,COG0012@1,COG0012@2	NA|NA|NA	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NIOIMGPL_00529	398513.BBNG_01124	9.5e-22	108.6	Bifidobacteriales	XK27_00240												Bacteria	2HZGJ@201174,4D0D3@85004,COG1510@1,COG1510@2,COG3177@1,COG3177@2	NA|NA|NA	K	Fic/DOC family
NIOIMGPL_00530	702459.BBPR_1195	1.4e-207	728.8	Bifidobacteriales	XK27_00240												Bacteria	2HZGJ@201174,4D0D3@85004,COG1510@1,COG1510@2,COG3177@1,COG3177@2	NA|NA|NA	K	Fic/DOC family
NIOIMGPL_00531	702459.BBPR_1194	2.5e-119	434.9	Bifidobacteriales													Bacteria	2I61X@201174,4D2U1@85004,COG1246@1,COG1246@2	NA|NA|NA	E	Psort location Cytoplasmic, score 8.87
NIOIMGPL_00532	398513.BBNG_01121	5.6e-59	233.4	Bifidobacteriales	yccF												Bacteria	2IKS5@201174,4D11K@85004,COG3304@1,COG3304@2	NA|NA|NA	S	Inner membrane component domain
NIOIMGPL_00533	702459.BBPR_1192	1.5e-155	555.4	Bifidobacteriales	ksgA		2.1.1.182	ko:K02528			R10716	RC00003,RC03257	ko00000,ko01000,ko03009				Bacteria	2I2II@201174,4CZIK@85004,COG0030@1,COG0030@2	NA|NA|NA	J	Methyltransferase domain
NIOIMGPL_00534	702459.BBPR_1191	3.9e-59	234.6	Bifidobacteriales													Bacteria	2IHSV@201174,4D0ZF@85004,COG1917@1,COG1917@2	NA|NA|NA	S	Cupin 2, conserved barrel domain protein
NIOIMGPL_00535	702459.BBPR_1190	4.1e-250	870.5	Bifidobacteriales													Bacteria	2IB6I@201174,4D0BZ@85004,COG0515@1,COG0515@2	NA|NA|NA	KLT	Protein tyrosine kinase
NIOIMGPL_00536	398513.BBNG_01117	4.5e-79	300.4	Bifidobacteriales													Bacteria	2E529@1,2IIU2@201174,32ZVG@2,4D0Z5@85004	NA|NA|NA	K	Psort location Cytoplasmic, score
NIOIMGPL_00537	702459.BBPR_1188	1.2e-148	532.7	Bifidobacteriales													Bacteria	2DNFW@1,2IANA@201174,32XAQ@2,4D0ED@85004	NA|NA|NA		
NIOIMGPL_00538	78345.BMERY_0008	4e-09	67.0	Bifidobacteriales													Bacteria	2DNFW@1,2IANA@201174,32XAQ@2,4D0ED@85004	NA|NA|NA		
NIOIMGPL_00539	216816.GS08_04270	2.7e-22	110.9	Bifidobacteriales													Bacteria	2C3F9@1,2H1CK@201174,2ZWBA@2,4D1N7@85004	NA|NA|NA		
NIOIMGPL_00540	398513.BBNG_01113	1.3e-197	695.7	Bifidobacteriales													Bacteria	2HUEV@201174,4CZKS@85004,COG4260@1,COG4260@2	NA|NA|NA	S	Short C-terminal domain
NIOIMGPL_00541	398513.BBNG_01112	1.2e-89	335.9	Bifidobacteriales													Bacteria	2E443@1,2II6X@201174,32Z0D@2,4D0ZD@85004	NA|NA|NA	S	Helix-turn-helix
NIOIMGPL_00542	398513.BBNG_01111	2.8e-66	257.7	Bifidobacteriales													Bacteria	2IKXW@201174,4D10G@85004,COG3824@1,COG3824@2	NA|NA|NA	S	Zincin-like metallopeptidase
NIOIMGPL_00543	398513.BBNG_01110	1.2e-34	151.8	Bifidobacteriales	yhcC			ko:K07069					ko00000				Bacteria	2GTG6@201174,4D1FH@85004,COG3478@1,COG3478@2	NA|NA|NA	S	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
NIOIMGPL_00544	398513.BBNG_01109	1.5e-24	119.0	Bifidobacteriales													Bacteria	2AXVJ@1,2IRBS@201174,31PWU@2,4D18S@85004	NA|NA|NA		
NIOIMGPL_00545	398513.BBNG_01108	2.7e-73	281.2	Bifidobacteriales	def2		3.5.1.31,3.5.1.88	ko:K01450,ko:K01462	ko00270,ko00630,map00270,map00630		R00653	RC00165,RC00323	ko00000,ko00001,ko01000				Bacteria	2IJQ5@201174,4D14S@85004,COG0242@1,COG0242@2	NA|NA|NA	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins
NIOIMGPL_00546	398513.BBNG_01107	1e-124	452.6	Bifidobacteriales	ypfH	GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0052689		ko:K06999					ko00000				Bacteria	2I5NR@201174,4CZJQ@85004,COG0400@1,COG0400@2	NA|NA|NA	S	Phospholipase/Carboxylesterase
NIOIMGPL_00547	702459.BBPR_1180	0.0	1274.2	Bifidobacteriales	pbpB		2.7.11.1,3.4.16.4	ko:K03587,ko:K08384,ko:K08724,ko:K08884,ko:K12132	ko00550,ko01501,map00550,map01501				ko00000,ko00001,ko01000,ko01001,ko01011,ko03036				Bacteria	2IAHD@201174,4D094@85004,COG2815@1,COG2815@2	NA|NA|NA	S	PASTA domain
NIOIMGPL_00549	702459.BBPR_1177	1.7e-290	1004.6	Bifidobacteriales			2.4.1.166	ko:K00745					ko00000,ko01000		GT2		Bacteria	2I2GT@201174,4CZ0W@85004,COG0463@1,COG0463@2,COG3613@1,COG3613@2	NA|NA|NA	M	Glycosyltransferase like family 2
NIOIMGPL_00550	702459.BBPR_1176	4.2e-118	430.6	Bifidobacteriales			3.1.3.27	ko:K18697	ko00564,map00564		R02029	RC00017	ko00000,ko00001,ko01000				Bacteria	2GMVR@201174,4D0CF@85004,COG0560@1,COG0560@2	NA|NA|NA	E	haloacid dehalogenase-like hydrolase
NIOIMGPL_00551	398513.BBNG_01101	1.9e-144	518.5	Bifidobacteriales	rlrG			ko:K21900					ko00000,ko03000				Bacteria	2HZCS@201174,4CZT1@85004,COG0583@1,COG0583@2	NA|NA|NA	K	Bacterial regulatory helix-turn-helix protein, lysR family
NIOIMGPL_00552	398513.BBNG_01100	2.7e-186	657.9	Bifidobacteriales	MA20_14895												Bacteria	2GS6E@201174,4CZWB@85004,COG2855@1,COG2855@2	NA|NA|NA	S	Conserved hypothetical protein 698
NIOIMGPL_00553	398513.BBNG_01099	8.7e-56	223.4	Actinobacteria	estB			ko:K06999					ko00000				Bacteria	2GNIF@201174,COG0400@1,COG0400@2	NA|NA|NA	S	Phospholipase/Carboxylesterase
NIOIMGPL_00554	398513.BBNG_01098	1.1e-158	565.8	Bifidobacteriales			3.1.3.73	ko:K02226,ko:K07814	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000,ko02022				Bacteria	2GN7B@201174,4CZFM@85004,COG0406@1,COG0406@2	NA|NA|NA	G	Phosphoglycerate mutase family
NIOIMGPL_00555	398513.BBNG_01097	2.4e-237	827.8	Bifidobacteriales	rutG	GO:0003674,GO:0005215,GO:0005350,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0006810,GO:0006855,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0015205,GO:0015210,GO:0015238,GO:0015851,GO:0015855,GO:0015857,GO:0015893,GO:0016020,GO:0016021,GO:0017144,GO:0019860,GO:0022857,GO:0031224,GO:0031226,GO:0034641,GO:0042221,GO:0042493,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072527,GO:0072529,GO:0072531,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1903791,GO:1904082		ko:K02824,ko:K03458,ko:K09016					ko00000,ko02000	2.A.40,2.A.40.1.1,2.A.40.1.2,2.A.40.1.3		iECO103_1326.ECO103_1052,iECUMN_1333.ECUMN_1189	Bacteria	2GMH6@201174,4CZR8@85004,COG2233@1,COG2233@2	NA|NA|NA	F	Permease family
NIOIMGPL_00556	702459.BBPR_1170	2e-57	228.0	Bifidobacteriales													Bacteria	2I65G@201174,4D2YB@85004,COG1917@1,COG1917@2	NA|NA|NA	K	AraC-like ligand binding domain
NIOIMGPL_00558	398513.BBNG_01095	3.7e-51	207.2	Bacteria													Bacteria	COG4221@1,COG4221@2	NA|NA|NA	IQ	oxidoreductase activity
NIOIMGPL_00559	702459.BBPR_1167	4.2e-136	490.7	Bifidobacteriales	ybbM			ko:K02069		M00211			ko00000,ko00002,ko02000	9.B.25.1			Bacteria	2GMHX@201174,4CYRQ@85004,COG0390@1,COG0390@2	NA|NA|NA	V	Uncharacterised protein family (UPF0014)
NIOIMGPL_00560	702459.BBPR_1166	7.5e-135	486.5	Bifidobacteriales	ybbL			ko:K01990,ko:K02003,ko:K02068,ko:K05685	ko02010,map02010	M00211,M00254,M00258,M00709			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12			Bacteria	2I8QP@201174,4CZZG@85004,COG1136@1,COG1136@2	NA|NA|NA	V	ATPases associated with a variety of cellular activities
NIOIMGPL_00561	398513.BBNG_01092	3.2e-161	574.3	Bifidobacteriales	IV02_28330		2.1.1.185,2.1.1.34	ko:K00556,ko:K03218,ko:K03437					ko00000,ko01000,ko03009,ko03016				Bacteria	2GJI6@201174,4CYZQ@85004,COG0566@1,COG0566@2	NA|NA|NA	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIOIMGPL_00562	398513.BBNG_01090	2.5e-91	341.3	Bifidobacteriales	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	2GJGG@201174,4CZ78@85004,COG0016@1,COG0016@2	NA|NA|NA	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NIOIMGPL_00563	702459.BBPR_1163	2.7e-125	454.9	Bifidobacteriales	pheT	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	2GMFD@201174,4CYUM@85004,COG0072@1,COG0072@2,COG0073@1,COG0073@2	NA|NA|NA	J	Phenylalanyl-tRNA synthetase beta
NIOIMGPL_00564	702459.BBPR_1163	0.0	1154.0	Bifidobacteriales	pheT	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	2GMFD@201174,4CYUM@85004,COG0072@1,COG0072@2,COG0073@1,COG0073@2	NA|NA|NA	J	Phenylalanyl-tRNA synthetase beta
NIOIMGPL_00565	398513.BBNG_01088	1.4e-89	335.9	Bifidobacteriales													Bacteria	2AHAX@1,2IPJ5@201174,317M8@2,4D11M@85004	NA|NA|NA		
NIOIMGPL_00566	398513.BBNG_01087	1e-204	719.2	Bifidobacteriales	argC	GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000				Bacteria	2GKQK@201174,4CZNC@85004,COG0002@1,COG0002@2	NA|NA|NA	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NIOIMGPL_00567	702459.BBPR_1160	1.3e-215	755.4	Bifidobacteriales	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35,2.7.2.8	ko:K00620,ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282,R02649	RC00002,RC00004,RC00043,RC00064	ko00000,ko00001,ko00002,ko01000				Bacteria	2GIW0@201174,4CZQQ@85004,COG1364@1,COG1364@2	NA|NA|NA	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NIOIMGPL_00568	398513.BBNG_01084	9.2e-164	582.8	Bifidobacteriales	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000			iHN637.CLJU_RS10565,iJN678.argB,iLJ478.TM1784	Bacteria	2GKDS@201174,4CYYX@85004,COG0548@1,COG0548@2	NA|NA|NA	E	Belongs to the acetylglutamate kinase family. ArgB subfamily
NIOIMGPL_00569	702459.BBPR_1158	9.5e-247	859.0	Bifidobacteriales	argD	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	2GKE9@201174,4CZGW@85004,COG4992@1,COG4992@2	NA|NA|NA	E	Aminotransferase class-III
NIOIMGPL_00570	398513.BBNG_01082	9.5e-183	646.0	Bifidobacteriales	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000				Bacteria	2GJ6H@201174,4CZGN@85004,COG0078@1,COG0078@2	NA|NA|NA	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NIOIMGPL_00571	702459.BBPR_1156	1.4e-84	318.9	Bifidobacteriales	argR	GO:0000820,GO:0000821,GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006259,GO:0006310,GO:0006355,GO:0006520,GO:0006521,GO:0006525,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016043,GO:0016597,GO:0019219,GO:0019222,GO:0019752,GO:0022607,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031333,GO:0031334,GO:0031406,GO:0032991,GO:0032993,GO:0033238,GO:0033241,GO:0034214,GO:0034618,GO:0034641,GO:0036094,GO:0042150,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043254,GO:0043436,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044424,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051259,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140110,GO:1900079,GO:1900081,GO:1901360,GO:1901363,GO:1901564,GO:1901605,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2000144,GO:2000282,GO:2001141		ko:K03402					ko00000,ko03000				Bacteria	2GKA5@201174,4D0VM@85004,COG1438@1,COG1438@2	NA|NA|NA	K	Regulates arginine biosynthesis genes
NIOIMGPL_00572	398513.BBNG_01080	5e-237	826.6	Bifidobacteriales	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147			iNJ661.Rv1658	Bacteria	2GK96@201174,4CZ2R@85004,COG0137@1,COG0137@2	NA|NA|NA	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily
NIOIMGPL_00573	702459.BBPR_1151	1.6e-53	215.7	Bifidobacteriales			3.1.21.3	ko:K01154					ko00000,ko01000,ko02048				Bacteria	2IPR0@201174,4D10W@85004,COG0732@1,COG0732@2	NA|NA|NA	V	type I restriction modification DNA specificity domain
NIOIMGPL_00574	398513.BBNG_01078	8.2e-176	622.9	Bifidobacteriales													Bacteria	2HUXN@201174,4CZ21@85004,COG0582@1,COG0582@2	NA|NA|NA	L	Phage integrase family
NIOIMGPL_00575	398513.BBNG_01756	2.4e-139	501.5	Bifidobacteriales													Bacteria	2CBRJ@1,2GKSC@201174,2Z7W0@2,4CZAS@85004	NA|NA|NA	S	LPXTG-motif cell wall anchor domain protein
NIOIMGPL_00576	326426.Bbr_1889	4.1e-284	983.4	Bifidobacteriales													Bacteria	2CBRJ@1,2GKSC@201174,2Z7W0@2,4CZAS@85004	NA|NA|NA	S	LPXTG-motif cell wall anchor domain protein
NIOIMGPL_00577	566552.BIFCAT_01421	1.7e-114	418.7	Bifidobacteriales													Bacteria	2CBRJ@1,2GKSC@201174,2Z7W0@2,4CZAS@85004	NA|NA|NA	S	LPXTG-motif cell wall anchor domain protein
NIOIMGPL_00578	398513.BBNG_01740	1e-187	662.5	Bifidobacteriales	MA20_16500		1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	2GKTT@201174,4CZRS@85004,COG0111@1,COG0111@2	NA|NA|NA	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIOIMGPL_00579	398513.BBNG_01739	2.8e-154	551.2	Bifidobacteriales	sapF			ko:K02032,ko:K19230	ko01503,ko02010,ko02024,map01503,map02010,map02024	M00239,M00739			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.5			Bacteria	2GP46@201174,4CYXD@85004,COG4608@1,COG4608@2	NA|NA|NA	E	ATPases associated with a variety of cellular activities
NIOIMGPL_00580	398513.BBNG_01738	3.3e-141	507.7	Bifidobacteriales	oppD			ko:K02031	ko02024,map02024	M00239			ko00000,ko00001,ko00002,ko02000	3.A.1.5			Bacteria	2GIXV@201174,4CZ3U@85004,COG0444@1,COG0444@2	NA|NA|NA	EP	oligopeptide transport protein of the ABC superfamily, ATP-binding component
NIOIMGPL_00581	702459.BBPR_1349	1.4e-162	578.9	Bifidobacteriales				ko:K02034	ko02024,map02024	M00239			ko00000,ko00001,ko00002,ko02000	3.A.1.5			Bacteria	2GNQ5@201174,4CZ84@85004,COG1173@1,COG1173@2	NA|NA|NA	EP	Binding-protein-dependent transport system inner membrane component
NIOIMGPL_00582	398513.BBNG_01736	5.5e-170	603.6	Bifidobacteriales				ko:K02033	ko02024,map02024	M00239			ko00000,ko00001,ko00002,ko02000	3.A.1.5			Bacteria	2GK0Z@201174,4CYST@85004,COG0601@1,COG0601@2	NA|NA|NA	P	Binding-protein-dependent transport system inner membrane component
NIOIMGPL_00583	398513.BBNG_01735	4.6e-310	1069.7	Bifidobacteriales				ko:K02035	ko02024,map02024	M00239			ko00000,ko00001,ko00002,ko02000	3.A.1.5			Bacteria	2GJ4B@201174,4CYWF@85004,COG0747@1,COG0747@2	NA|NA|NA	E	ABC transporter, substrate-binding protein, family 5
NIOIMGPL_00584	398513.BBNG_01734	1.1e-142	512.7	Bifidobacteriales	coaX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_1986	Bacteria	2GMRQ@201174,4CZQS@85004,COG1521@1,COG1521@2	NA|NA|NA	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NIOIMGPL_00585	702459.BBPR_1353	1.7e-273	948.0	Bifidobacteriales				ko:K02027		M00207			ko00000,ko00002,ko02000	3.A.1.1			Bacteria	2GJIP@201174,4CYRE@85004,COG1653@1,COG1653@2	NA|NA|NA	G	Bacterial extracellular solute-binding protein
NIOIMGPL_00586	702459.BBPR_1354	5.7e-58	229.9	Bacteria				ko:K02027		M00207			ko00000,ko00002,ko02000	3.A.1.1			Bacteria	COG1653@1,COG1653@2	NA|NA|NA	G	carbohydrate transport
NIOIMGPL_00587	702459.BBPR_1355	0.0	1397.5	Bifidobacteriales	lacZ5		3.2.1.23	ko:K12308	ko00052,map00052		R01105	RC00452	ko00000,ko00001,ko01000				Bacteria	2GMDT@201174,4CZ38@85004,COG1874@1,COG1874@2	NA|NA|NA	G	Psort location Cytoplasmic, score 8.87
NIOIMGPL_00588	398513.BBNG_01730	1.6e-64	251.9	Bifidobacteriales				ko:K02026		M00207			ko00000,ko00002,ko02000	3.A.1.1			Bacteria	2GJPZ@201174,4CYV5@85004,COG0395@1,COG0395@2	NA|NA|NA	G	ABC transporter permease
NIOIMGPL_00589	398513.BBNG_01730	7.7e-43	179.5	Bifidobacteriales				ko:K02026		M00207			ko00000,ko00002,ko02000	3.A.1.1			Bacteria	2GJPZ@201174,4CYV5@85004,COG0395@1,COG0395@2	NA|NA|NA	G	ABC transporter permease
NIOIMGPL_00590	702459.BBPR_1358	9.4e-186	656.0	Bifidobacteriales				ko:K02529					ko00000,ko03000				Bacteria	2GK1X@201174,4CZWK@85004,COG1609@1,COG1609@2	NA|NA|NA	K	Periplasmic binding protein domain
NIOIMGPL_00591	1437609.BCAL_0460	2.9e-20	104.4	Bifidobacteriales	ghrA												Bacteria	2GP09@201174,4CZUN@85004,COG0111@1,COG0111@2	NA|NA|NA	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
NIOIMGPL_00592	702459.BBPR_1360	0.0	2813.5	Bifidobacteriales			3.2.1.51	ko:K01206	ko00511,map00511				ko00000,ko00001,ko01000,ko04147		GH29		Bacteria	2I650@201174,4CZPN@85004,COG3669@1,COG3669@2	NA|NA|NA	G	Alpha-L-fucosidase
NIOIMGPL_00594	398513.BBNG_01725	5.4e-125	453.8	Bifidobacteriales	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	2GK9M@201174,4CYT7@85004,COG0060@1,COG0060@2	NA|NA|NA	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NIOIMGPL_00595	398513.BBNG_01725	0.0	1378.6	Bifidobacteriales	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	2GK9M@201174,4CYT7@85004,COG0060@1,COG0060@2	NA|NA|NA	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NIOIMGPL_00596	702459.BBPR_1363	8.5e-55	219.5	Bifidobacteriales	yvlD			ko:K08972					ko00000				Bacteria	2HZND@201174,4D117@85004,COG1950@1,COG1950@2	NA|NA|NA	S	Mycobacterial 4 TMS phage holin, superfamily IV
NIOIMGPL_00597	702459.BBPR_1364	4.9e-276	956.4	Bifidobacteriales	aldH		1.2.1.3,1.2.1.5	ko:K00128,ko:K00129	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00350,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00980,ko00981,ko00982,ko01100,ko01110,ko01120,ko01130,ko05204,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00350,map00360,map00380,map00410,map00561,map00620,map00625,map00903,map00980,map00981,map00982,map01100,map01110,map01120,map01130,map05204	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02536,R02537,R02549,R02678,R02695,R02697,R02940,R02957,R03283,R03300,R03302,R03869,R04065,R04506,R04882,R04883,R04888,R04889,R04891,R04892,R04903,R04996,R05050,R05237,R05238,R05286,R06366,R07104,R08146,R08282,R08283,R08307	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500,RC01735	ko00000,ko00001,ko00002,ko01000				Bacteria	2GIWZ@201174,4CZQF@85004,COG1012@1,COG1012@2	NA|NA|NA	C	Aldehyde dehydrogenase family
NIOIMGPL_00598	632245.CLP_3939	2.3e-60	239.6	Clostridia	bcgIB		2.1.1.72,3.1.21.3	ko:K01154,ko:K03427					ko00000,ko01000,ko02048				Bacteria	1V2VF@1239,24K9B@186801,COG0732@1,COG0732@2	NA|NA|NA	V	Type I restriction modification DNA specificity domain
NIOIMGPL_00599	1423724.BAMM01000038_gene2163	1.9e-251	875.2	Bacilli													Bacteria	1USEH@1239,4HDU1@91061,COG0286@1,COG0286@2	NA|NA|NA	V	Type I restriction-modification system methyltransferase subunit()
NIOIMGPL_00600	1437609.BCAL_2152	1.1e-23	115.2	Bifidobacteriales	relB			ko:K07473					ko00000,ko02048				Bacteria	2GRBT@201174,4D1GU@85004,COG3077@1,COG3077@2	NA|NA|NA	L	RelB antitoxin
NIOIMGPL_00601	1437608.BBIA_2059	7.3e-81	307.4	Bifidobacteriales													Bacteria	2IF22@201174,4D0MK@85004,COG3677@1,COG3677@2	NA|NA|NA	L	Transposase
NIOIMGPL_00602	702459.BBPR_1365	9.2e-127	459.9	Bifidobacteriales	XK27_08050												Bacteria	2GJ1U@201174,4CYTU@85004,COG0330@1,COG0330@2	NA|NA|NA	O	prohibitin homologues
NIOIMGPL_00603	398513.BBNG_01721	4.5e-244	850.1	Bifidobacteriales			2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100		R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000				Bacteria	2I8JG@201174,4CZ6W@85004,COG2873@1,COG2873@2	NA|NA|NA	E	Cys/Met metabolism PLP-dependent enzyme
NIOIMGPL_00604	398513.BBNG_01720	2e-233	814.7	Bifidobacteriales	metC		4.4.1.8	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000				Bacteria	2GJ5S@201174,4CZKK@85004,COG0626@1,COG0626@2	NA|NA|NA	E	Cys/Met metabolism PLP-dependent enzyme
NIOIMGPL_00605	398513.BBNG_01719	1.4e-259	901.7	Bifidobacteriales	nox		1.6.3.4	ko:K17869					ko00000,ko01000				Bacteria	2H7WY@201174,4CZXP@85004,COG0446@1,COG0446@2	NA|NA|NA	C	Pyridine nucleotide-disulphide oxidoreductase
NIOIMGPL_00606	702459.BBPR_1369	2.9e-224	784.3	Bifidobacteriales	glxK	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130		R08572	RC00002,RC00428	ko00000,ko00001,ko01000				Bacteria	2GKHX@201174,4CZRH@85004,COG1929@1,COG1929@2	NA|NA|NA	G	Belongs to the glycerate kinase type-1 family
NIOIMGPL_00607	398513.BBNG_01717	0.0	1702.6	Bifidobacteriales	macB_2			ko:K02003,ko:K02004,ko:K05685	ko02010,map02010	M00258,M00709			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12			Bacteria	2GK3I@201174,4D0AY@85004,COG0577@1,COG0577@2,COG1136@1,COG1136@2	NA|NA|NA	V	ATPases associated with a variety of cellular activities
NIOIMGPL_00608	398513.BBNG_01716	1.8e-32	144.8	Bifidobacteriales	ctpE			ko:K12952					ko00000,ko01000	3.A.3.23			Bacteria	2GJJC@201174,4D07Z@85004,COG0474@1,COG0474@2	NA|NA|NA	P	E1-E2 ATPase
NIOIMGPL_00609	702459.BBPR_1371	2.4e-184	651.4	Bifidobacteriales	ctpE			ko:K12952					ko00000,ko01000	3.A.3.23			Bacteria	2GJJC@201174,4D07Z@85004,COG0474@1,COG0474@2	NA|NA|NA	P	E1-E2 ATPase
NIOIMGPL_00610	398513.BBNG_01715	2.9e-54	217.6	Bifidobacteriales	racA			ko:K03713,ko:K11686					ko00000,ko03000,ko03036				Bacteria	2HZMI@201174,4D0Y1@85004,COG0789@1,COG0789@2	NA|NA|NA	K	MerR, DNA binding
NIOIMGPL_00611	702459.BBPR_1374	8.4e-198	696.0	Bifidobacteriales	yghZ			ko:K19265					ko00000,ko01000				Bacteria	2GMT5@201174,4CZ25@85004,COG0667@1,COG0667@2	NA|NA|NA	C	Aldo/keto reductase family
NIOIMGPL_00612	398513.BBNG_01713	1.9e-100	371.7	Bifidobacteriales	dnaQ		2.7.7.7	ko:K02342,ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	2I2FU@201174,4D10C@85004,COG2176@1,COG2176@2	NA|NA|NA	L	Exonuclease, DNA polymerase III, epsilon subunit family
NIOIMGPL_00613	398513.BBNG_01712	1.1e-250	872.1	Bifidobacteriales	gltA	GO:0003674,GO:0003824,GO:0004108,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019752,GO:0036440,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046912,GO:0055114,GO:0071704,GO:0071944,GO:0072350	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000			iIT341.HP0026,iYL1228.KPN_00727	Bacteria	2GJ7E@201174,4CZ2J@85004,COG0372@1,COG0372@2	NA|NA|NA	C	Citrate synthase, C-terminal domain
NIOIMGPL_00614	398513.BBNG_01711	1.1e-149	535.8	Bifidobacteriales	map		3.4.11.18	ko:K01265					ko00000,ko01000,ko01002				Bacteria	2GKKB@201174,4CZAA@85004,COG0024@1,COG0024@2	NA|NA|NA	E	Methionine aminopeptidase
NIOIMGPL_00615	398513.BBNG_01710	3.8e-125	454.5	Bifidobacteriales													Bacteria	2H3AT@201174,4D00R@85004,COG3247@1,COG3247@2	NA|NA|NA	S	Short repeat of unknown function (DUF308)
NIOIMGPL_00616	702459.BBPR_1379	0.0	1158.7	Bifidobacteriales	pepO		3.4.24.71	ko:K01415,ko:K07386					ko00000,ko01000,ko01002,ko04147				Bacteria	2GNJY@201174,4CYVU@85004,COG3590@1,COG3590@2	NA|NA|NA	O	Peptidase family M13
NIOIMGPL_00617	398513.BBNG_01709	1.6e-40	171.4	Bifidobacteriales	pepO		3.4.24.71	ko:K01415,ko:K07386					ko00000,ko01000,ko01002,ko04147				Bacteria	2GNJY@201174,4CYVU@85004,COG3590@1,COG3590@2	NA|NA|NA	O	Peptidase family M13
NIOIMGPL_00618	398513.BBNG_01708	8.2e-117	426.4	Bifidobacteriales				ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440				ko00000,ko00001,ko03029,ko03032,ko03400				Bacteria	2GQIQ@201174,4D17E@85004,COG0629@1,COG0629@2	NA|NA|NA	L	Single-strand binding protein family
NIOIMGPL_00619	702459.BBPR_1381	2.6e-43	181.0	Bifidobacteriales													Bacteria	2B89A@1,2H5K4@201174,321HX@2,4D293@85004	NA|NA|NA		
NIOIMGPL_00620	702459.BBPR_1382	0.0	1194.9	Bifidobacteriales	proS	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	2GJ9G@201174,4CZ6E@85004,COG0442@1,COG0442@2	NA|NA|NA	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NIOIMGPL_00622	702459.BBPR_1386	1e-270	938.7	Bifidobacteriales	recD2		3.6.4.12	ko:K15255					ko00000,ko01000,ko03029,ko03032				Bacteria	2HFY1@201174,4CZ0C@85004,COG0507@1,COG0507@2	NA|NA|NA	L	PIF1-like helicase
NIOIMGPL_00623	702459.BBPR_1387	7.6e-160	569.7	Bifidobacteriales	supH												Bacteria	2HZBZ@201174,4CZNM@85004,COG0561@1,COG0561@2	NA|NA|NA	S	Sucrose-6F-phosphate phosphohydrolase
NIOIMGPL_00624	398513.BBNG_01703	2.8e-122	444.5	Bifidobacteriales	orn	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360		ko:K13288	ko03008,map03008				ko00000,ko00001,ko01000,ko03009,ko03019				Bacteria	2GJR7@201174,4CYZY@85004,COG1949@1,COG1949@2	NA|NA|NA	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NIOIMGPL_00625	398513.BBNG_01701	0.0	1254.6	Bifidobacteriales			3.2.1.10,3.2.1.20,3.2.1.93	ko:K01182,ko:K01187,ko:K01226	ko00052,ko00500,ko01100,map00052,map00500,map01100		R00028,R00801,R00802,R00837,R01718,R01791,R06087,R06088,R06113,R06199	RC00028,RC00049,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000		GH13,GH31		Bacteria	2GKS4@201174,4CZ1E@85004,COG0366@1,COG0366@2	NA|NA|NA	G	Alpha-amylase domain
NIOIMGPL_00626	398513.BBNG_01700	3.5e-288	996.9	Bifidobacteriales	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006183,GO:0006195,GO:0006204,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009125,GO:0009126,GO:0009127,GO:0009128,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009154,GO:0009156,GO:0009158,GO:0009161,GO:0009163,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009169,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009261,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046037,GO:0046039,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	2GITZ@201174,4CZ2S@85004,COG0516@1,COG0516@2,COG0517@1,COG0517@2	NA|NA|NA	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NIOIMGPL_00627	398513.BBNG_01699	1e-191	676.0	Bifidobacteriales	tagO	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576	2.7.8.33,2.7.8.35	ko:K02851			R08856	RC00002	ko00000,ko01000,ko01003,ko01005				Bacteria	2GIT7@201174,4CZ4P@85004,COG0472@1,COG0472@2	NA|NA|NA	M	Glycosyl transferase family 4
NIOIMGPL_00628	398513.BBNG_01698	5.2e-116	423.7	Bifidobacteriales	ywlC	GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	2.7.7.87	ko:K07566			R10463	RC00745	ko00000,ko01000,ko03009,ko03016				Bacteria	2GK2X@201174,4CYVA@85004,COG0009@1,COG0009@2	NA|NA|NA	J	Belongs to the SUA5 family
NIOIMGPL_00629	398513.BBNG_01697	4.1e-20	103.2	Bifidobacteriales			2.3.1.79	ko:K00661					ko00000,ko01000				Bacteria	2GNUB@201174,4CZ5K@85004,COG0110@1,COG0110@2	NA|NA|NA	S	Bacterial transferase hexapeptide repeat protein
NIOIMGPL_00630	702459.BBPR_1395	6.3e-179	633.3	Bifidobacteriales	prmC		2.1.1.297	ko:K02493			R10806	RC00003,RC03279	ko00000,ko01000,ko03012				Bacteria	2GMH1@201174,4CZB3@85004,COG2890@1,COG2890@2	NA|NA|NA	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NIOIMGPL_00631	398513.BBNG_01695	1.3e-188	665.6	Bifidobacteriales	prfA			ko:K02835					ko00000,ko03012				Bacteria	2GJWG@201174,4CYX4@85004,COG0216@1,COG0216@2	NA|NA|NA	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NIOIMGPL_00632	398513.BBNG_01694	3.9e-36	156.8	Bifidobacteriales	rpmE	GO:0008150,GO:0040007		ko:K02909	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	2IQ4I@201174,4D17F@85004,COG0254@1,COG0254@2	NA|NA|NA	J	Binds the 23S rRNA
NIOIMGPL_00634	702459.BBPR_1398	2.9e-193	681.0	Bifidobacteriales													Bacteria	2GIRA@201174,4D1HZ@85004,COG4977@1,COG4977@2	NA|NA|NA	K	helix_turn_helix, arabinose operon control protein
NIOIMGPL_00635	398513.BBNG_01692	2.6e-163	581.3	Bifidobacteriales	glcU			ko:K05340					ko00000,ko02000	2.A.7.5			Bacteria	2IBUA@201174,4CZIZ@85004,COG4975@1,COG4975@2	NA|NA|NA	G	Sugar transport protein
NIOIMGPL_00636	398513.BBNG_01691	5.7e-178	630.2	Bifidobacteriales	iolG		1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130		R01183,R09951	RC00182	ko00000,ko00001,ko01000				Bacteria	2GJCY@201174,4D1RS@85004,COG0673@1,COG0673@2	NA|NA|NA	S	Oxidoreductase family, C-terminal alpha/beta domain
NIOIMGPL_00637	398513.BBNG_01690	6e-257	892.9	Bifidobacteriales	cma		2.1.1.79	ko:K00574					ko00000,ko01000				Bacteria	2GJ94@201174,4D016@85004,COG2230@1,COG2230@2	NA|NA|NA	M	Mycolic acid cyclopropane synthetase
NIOIMGPL_00638	398513.BBNG_01689	1.4e-106	392.5	Bacteria													Bacteria	2DPD8@1,331K3@2	NA|NA|NA		
NIOIMGPL_00639	398513.BBNG_01687	1.1e-169	602.4	Bifidobacteriales	yeaD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716	4.2.1.9,5.1.3.15	ko:K01687,ko:K01792	ko00010,ko00290,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00010,map00290,map00770,map01100,map01110,map01120,map01130,map01210,map01230	M00019,M00570	R01209,R02739,R04441,R05070	RC00468,RC00563,RC01714	ko00000,ko00001,ko00002,ko01000				Bacteria	2IIUH@201174,4CZWN@85004,COG0676@1,COG0676@2	NA|NA|NA	G	Aldose 1-epimerase
NIOIMGPL_00640	702459.BBPR_1404	1.4e-140	506.1	Bifidobacteriales			3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504				Bacteria	2HZMP@201174,4D0YE@85004,COG2367@1,COG2367@2	NA|NA|NA	V	Beta-lactamase enzyme family
NIOIMGPL_00641	398513.BBNG_01685	4.1e-244	850.9	Bifidobacteriales	deaD		3.6.4.13	ko:K05592,ko:K11927	ko03018,map03018				ko00000,ko00001,ko01000,ko03009,ko03019				Bacteria	2GIUR@201174,4CZ4K@85004,COG0513@1,COG0513@2	NA|NA|NA	JKL	helicase superfamily c-terminal domain
NIOIMGPL_00642	398513.BBNG_01300	1.1e-45	188.7	Bifidobacteriales													Bacteria	2B78R@1,2IQGT@201174,320BB@2,4D178@85004	NA|NA|NA		
NIOIMGPL_00643	398513.BBNG_01301	4.7e-140	503.8	Bifidobacteriales	nfrA		1.5.1.38,1.5.1.39	ko:K19285,ko:K19286	ko00740,ko01100,map00740,map01100		R05705,R05706	RC00126	ko00000,ko00001,ko01000				Bacteria	2I65Z@201174,4CZ5R@85004,COG0778@1,COG0778@2	NA|NA|NA	C	Nitroreductase family
NIOIMGPL_00644	398513.BBNG_01302	7.1e-64	250.0	Bifidobacteriales													Bacteria	2B5DJ@1,2IRRR@201174,31Y80@2,4D1E6@85004	NA|NA|NA	S	Protein of unknown function (DUF4235)
NIOIMGPL_00645	398513.BBNG_01303	1.2e-131	475.7	Bifidobacteriales													Bacteria	2GNRS@201174,4CZD2@85004,COG0406@1,COG0406@2	NA|NA|NA	G	Phosphoglycerate mutase family
NIOIMGPL_00648	398513.BBNG_01306	2.9e-190	671.0	Bifidobacteriales													Bacteria	2GJBJ@201174,4CZ1Y@85004,COG1609@1,COG1609@2	NA|NA|NA	K	Psort location Cytoplasmic, score
NIOIMGPL_00649	702459.BBPR_1800	0.0	1333.5	Bifidobacteriales	phoA		3.1.3.1,3.1.3.39	ko:K01077,ko:K04342	ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020	M00126	R02135,R02228,R04620	RC00017,RC00078	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147				Bacteria	2GM8A@201174,4CYZF@85004,COG1785@1,COG1785@2	NA|NA|NA	P	Alkaline phosphatase homologues
NIOIMGPL_00650	398513.BBNG_01309	0.0	1123.6	Bifidobacteriales	dnaK	GO:0000302,GO:0000303,GO:0000305,GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016310,GO:0019222,GO:0019538,GO:0019899,GO:0030112,GO:0030162,GO:0030312,GO:0030313,GO:0031323,GO:0031325,GO:0031975,GO:0031982,GO:0032268,GO:0032270,GO:0033554,GO:0034599,GO:0034614,GO:0035375,GO:0036211,GO:0040007,GO:0042221,GO:0042603,GO:0043170,GO:0043226,GO:0043227,GO:0043230,GO:0043388,GO:0043412,GO:0044044,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046677,GO:0046688,GO:0046777,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051099,GO:0051101,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070613,GO:0070887,GO:0071450,GO:0071451,GO:0071704,GO:0071944,GO:0080090,GO:0097691,GO:1901564,GO:1901700,GO:1901701,GO:1903317,GO:1903319,GO:1903561,GO:2000677,GO:2000679		ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152				ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1			Bacteria	2GJTY@201174,4CZDX@85004,COG0443@1,COG0443@2	NA|NA|NA	O	Heat shock 70 kDa protein
NIOIMGPL_00651	702459.BBPR_1797	1.4e-58	233.0	Bifidobacteriales	grpE	GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009628,GO:0009986,GO:0009987,GO:0009991,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030246,GO:0030247,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071496,GO:0071840,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065		ko:K02652,ko:K03687					ko00000,ko02035,ko02044,ko03029,ko03110	3.A.15.2			Bacteria	2GP4F@201174,4CZJ6@85004,COG0576@1,COG0576@2	NA|NA|NA	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NIOIMGPL_00652	702459.BBPR_1796	1.4e-173	615.5	Bifidobacteriales	dnaJ1			ko:K03686,ko:K05516					ko00000,ko03029,ko03036,ko03110				Bacteria	2GJKK@201174,4CZ68@85004,COG0484@1,COG0484@2	NA|NA|NA	O	DnaJ molecular chaperone homology domain
NIOIMGPL_00653	702459.BBPR_1795	1.2e-86	325.9	Bifidobacteriales	hspR			ko:K13640					ko00000,ko03000				Bacteria	2IQJ4@201174,4D0Q7@85004,COG0789@1,COG0789@2	NA|NA|NA	K	transcriptional regulator, MerR family
NIOIMGPL_00654	702459.BBPR_1794	0.0	1410.2	Bifidobacteriales			3.2.1.18,3.2.1.51	ko:K01186,ko:K01206,ko:K20276	ko00511,ko00600,ko02024,ko04142,map00511,map00600,map02024,map04142		R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042,ko04147		GH29,GH33		Bacteria	2I0CJ@201174,4D02H@85004,COG1470@1,COG1470@2,COG4409@1,COG4409@2	NA|NA|NA	G	BNR repeat-like domain
NIOIMGPL_00655	702459.BBPR_1793	0.0	3314.2	Actinobacteria			3.2.1.18,3.2.1.51	ko:K01186,ko:K01206,ko:K20276	ko00511,ko00600,ko02024,ko04142,map00511,map00600,map02024,map04142		R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042,ko04147		GH29,GH33		Bacteria	2I0CJ@201174,COG1470@1,COG1470@2,COG2755@1,COG2755@2,COG4409@1,COG4409@2	NA|NA|NA	G	BNR Asp-box repeat
NIOIMGPL_00656	702459.BBPR_1792	1.8e-133	481.9	Bifidobacteriales													Bacteria	2GJNG@201174,4CYZV@85004,COG0637@1,COG0637@2	NA|NA|NA	S	HAD hydrolase, family IA, variant 3
NIOIMGPL_00658	398513.BBNG_01317	2.7e-126	458.0	Bifidobacteriales	dedA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K03975					ko00000				Bacteria	2GKGR@201174,4CZ7Y@85004,COG0586@1,COG0586@2	NA|NA|NA	S	SNARE associated Golgi protein
NIOIMGPL_00659	398513.BBNG_01318	2.3e-168	598.2	Bifidobacteriales	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.198	ko:K07056					ko00000,ko01000,ko03009				Bacteria	2GJ9Q@201174,4CZ03@85004,COG0313@1,COG0313@2	NA|NA|NA	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NIOIMGPL_00660	398513.BBNG_01319	1.5e-58	232.3	Bifidobacteriales													Bacteria	2B10P@1,2GS86@201174,31TDZ@2,4D1GZ@85004	NA|NA|NA		
NIOIMGPL_00661	702459.BBPR_1788	3.6e-130	471.1	Bifidobacteriales													Bacteria	2AU2N@1,2IJNI@201174,31JNZ@2,4D047@85004	NA|NA|NA		
NIOIMGPL_00662	702459.BBPR_1786	0.0	1288.9	Bifidobacteriales	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	2GK4S@201174,4CZ20@85004,COG0143@1,COG0143@2	NA|NA|NA	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NIOIMGPL_00663	398513.BBNG_01323	1.2e-80	305.8	Bifidobacteriales				ko:K19505,ko:K21885					ko00000,ko03000				Bacteria	2HGTM@201174,4D2JT@85004,COG0640@1,COG0640@2	NA|NA|NA	K	Transcriptional regulator
NIOIMGPL_00664	398513.BBNG_01326	5.3e-42	177.6	Bifidobacteriales	xylR	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	5.3.1.12	ko:K01812,ko:K02529,ko:K16210	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	2.A.2.5			Bacteria	2IAMT@201174,4CZNI@85004,COG1609@1,COG1609@2,COG2211@1,COG2211@2	NA|NA|NA	G	MFS/sugar transport protein
NIOIMGPL_00665	702459.BBPR_1783	9.9e-62	242.7	Bifidobacteriales	xylR	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	5.3.1.12	ko:K01812,ko:K02529,ko:K16210	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	2.A.2.5			Bacteria	2IAMT@201174,4CZNI@85004,COG1609@1,COG1609@2,COG2211@1,COG2211@2	NA|NA|NA	G	MFS/sugar transport protein
NIOIMGPL_00666	398513.BBNG_01326	1.1e-130	472.6	Bifidobacteriales	xylR	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	5.3.1.12	ko:K01812,ko:K02529,ko:K16210	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	2.A.2.5			Bacteria	2IAMT@201174,4CZNI@85004,COG1609@1,COG1609@2,COG2211@1,COG2211@2	NA|NA|NA	G	MFS/sugar transport protein
NIOIMGPL_00667	398513.BBNG_01327	5.9e-185	653.3	Bifidobacteriales	tatD			ko:K03424					ko00000,ko01000				Bacteria	2GMJJ@201174,4CYZI@85004,COG0084@1,COG0084@2	NA|NA|NA	L	TatD related DNase
NIOIMGPL_00668	702459.BBPR_1780	0.0	1504.2	Bifidobacteriales	kup	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662		ko:K03549					ko00000,ko02000	2.A.72			Bacteria	2GMPQ@201174,4CZM3@85004,COG3158@1,COG3158@2	NA|NA|NA	P	Transport of potassium into the cell
NIOIMGPL_00670	702459.BBPR_1778	1.3e-162	578.9	Bifidobacteriales													Bacteria	2IBFV@201174,4CYX2@85004,COG0121@1,COG0121@2	NA|NA|NA	S	Glutamine amidotransferase domain
NIOIMGPL_00671	702459.BBPR_1777	4.6e-137	493.8	Bifidobacteriales				ko:K02030,ko:K06950		M00236			ko00000,ko00002,ko02000	3.A.1.3			Bacteria	2GNQR@201174,4CYT9@85004,COG2206@1,COG2206@2	NA|NA|NA	T	HD domain
NIOIMGPL_00672	702459.BBPR_1776	4.2e-181	641.0	Bifidobacteriales				ko:K02003,ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	2GNFW@201174,4CZAW@85004,COG1136@1,COG1136@2	NA|NA|NA	V	ABC transporter
NIOIMGPL_00673	398513.BBNG_01333	1.4e-246	858.6	Bifidobacteriales													Bacteria	2GMGJ@201174,4CZBN@85004,COG0577@1,COG0577@2	NA|NA|NA	V	ABC transporter permease
NIOIMGPL_00674	702459.BBPR_1774	0.0	1314.3	Bifidobacteriales			2.1.1.107,2.1.1.294,2.7.1.181,2.7.11.1	ko:K02496,ko:K05802,ko:K08884,ko:K18827	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194,R10657,R10658	RC00002,RC00003,RC00078,RC00871,RC03220	ko00000,ko00001,ko00002,ko01000,ko01001,ko01005,ko02000	1.A.23.1.1			Bacteria	2I2HI@201174,4CYVN@85004,COG2959@1,COG2959@2	NA|NA|NA	H	Protein of unknown function (DUF4012)
NIOIMGPL_00675	702459.BBPR_1772	0.0	1132.5	Bifidobacteriales													Bacteria	2ANBU@1,2IAHJ@201174,31DA7@2,4CYW4@85004	NA|NA|NA	S	Psort location Cytoplasmic, score 8.87
NIOIMGPL_00676	398513.BBNG_01337	9.2e-164	582.8	Bifidobacteriales	thiG	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100		R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000			iECABU_c1320.ECABU_c45060,iECO26_1355.ECO26_5099,ic_1306.c4947	Bacteria	2GM62@201174,4CZ4A@85004,COG2022@1,COG2022@2	NA|NA|NA	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NIOIMGPL_00677	398513.BBNG_01338	8.7e-27	125.6	Bifidobacteriales	thiS		2.8.1.10	ko:K03149,ko:K03154	ko00730,ko01100,ko04122,map00730,map01100,map04122		R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000				Bacteria	2GSKM@201174,4D1GS@85004,COG2104@1,COG2104@2	NA|NA|NA	H	ThiS family
NIOIMGPL_00678	702459.BBPR_1769	5e-276	956.8	Bifidobacteriales													Bacteria	2DGST@1,2H2BZ@201174,2ZX5Y@2,4D1Y0@85004	NA|NA|NA		
NIOIMGPL_00679	702459.BBPR_1768	2.4e-64	251.5	Bifidobacteriales													Bacteria	2GMQQ@201174,4CZRJ@85004,COG1216@1,COG1216@2	NA|NA|NA	S	Glycosyltransferase, group 2 family protein
NIOIMGPL_00680	547043.BIFPSEUDO_03924	1.5e-79	302.0	Bifidobacteriales													Bacteria	2GISN@201174,4CZA9@85004,COG0582@1,COG0582@2	NA|NA|NA	L	Phage integrase family
NIOIMGPL_00681	547043.BIFPSEUDO_03924	5.7e-94	350.1	Bifidobacteriales													Bacteria	2GISN@201174,4CZA9@85004,COG0582@1,COG0582@2	NA|NA|NA	L	Phage integrase family
NIOIMGPL_00682	398513.BBNG_01198	3.1e-206	724.2	Bifidobacteriales													Bacteria	2GJVS@201174,4D2G3@85004,COG3591@1,COG3591@2	NA|NA|NA	E	Belongs to the peptidase S1B family
NIOIMGPL_00683	398513.BBNG_01199	1.1e-12	80.5	Bifidobacteriales													Bacteria	2E8P5@1,2I003@201174,303PB@2,4D2GC@85004	NA|NA|NA		
NIOIMGPL_00684	398513.BBNG_01202	0.0	1525.8	Bifidobacteriales	relA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230		R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009				Bacteria	2GJYQ@201174,4CZCW@85004,COG0317@1,COG0317@2	NA|NA|NA	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NIOIMGPL_00685	702459.BBPR_1248	1.7e-84	318.5	Bifidobacteriales	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23,4.1.1.36,6.3.2.5	ko:K01520,ko:K13038	ko00240,ko00770,ko00983,ko01100,map00240,map00770,map00983,map01100	M00053,M00120	R02100,R03269,R04231,R11896	RC00002,RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000,ko03400				Bacteria	2IHYY@201174,4CZUJ@85004,COG0756@1,COG0756@2	NA|NA|NA	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NIOIMGPL_00686	398513.BBNG_01204	1.4e-47	195.3	Bifidobacteriales													Bacteria	2ATJW@1,2I80Y@201174,3361K@2,4D10Y@85004	NA|NA|NA	S	Domain of unknown function (DUF4193)
NIOIMGPL_00687	398513.BBNG_01205	8.9e-174	616.3	Bifidobacteriales													Bacteria	29W72@1,2HZB4@201174,30HS9@2,4CZFJ@85004	NA|NA|NA	S	Protein of unknown function (DUF3071)
NIOIMGPL_00688	398513.BBNG_01206	1.9e-236	824.7	Bifidobacteriales													Bacteria	2GISU@201174,4CZCK@85004,COG1524@1,COG1524@2	NA|NA|NA	S	Type I phosphodiesterase / nucleotide pyrophosphatase
NIOIMGPL_00689	398513.BBNG_01208	0.0	1638.6	Bifidobacteriales	gyrA	GO:0005575,GO:0005622,GO:0005623,GO:0009330,GO:0032991,GO:0044424,GO:0044464	5.99.1.3	ko:K02469,ko:K02621					ko00000,ko01000,ko02048,ko03032,ko03036,ko03400				Bacteria	2GJ2Q@201174,4CYVH@85004,COG0188@1,COG0188@2	NA|NA|NA	L	DNA topoisomerase (ATP-hydrolyzing)
NIOIMGPL_00690	398513.BBNG_01209	0.0	2469.1	Bifidobacteriales	lhr	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360		ko:K03724					ko00000,ko01000,ko03400				Bacteria	2GJG3@201174,4D01F@85004,COG1201@1,COG1201@2	NA|NA|NA	L	DEAD DEAH box helicase
NIOIMGPL_00691	398513.BBNG_01209	6e-124	450.7	Bifidobacteriales	lhr	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360		ko:K03724					ko00000,ko01000,ko03400				Bacteria	2GJG3@201174,4D01F@85004,COG1201@1,COG1201@2	NA|NA|NA	L	DEAD DEAH box helicase
NIOIMGPL_00692	702459.BBPR_1254	1.1e-15	88.6	Bacteria				ko:K07727					ko00000,ko03000				Bacteria	COG3655@1,COG3655@2	NA|NA|NA	K	Transcriptional regulator
NIOIMGPL_00693	398513.BBNG_01211	4.9e-276	956.4	Bifidobacteriales	aspA		4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100		R00490	RC00316,RC02799	ko00000,ko00001,ko01000				Bacteria	2I2HG@201174,4CZ6N@85004,COG1027@1,COG1027@2	NA|NA|NA	E	Fumarase C C-terminus
NIOIMGPL_00694	398513.BBNG_01212	0.0	1451.4	Bifidobacteriales	gyrB2		5.99.1.3	ko:K02470					ko00000,ko01000,ko03032,ko03400				Bacteria	2GM1E@201174,4CYXR@85004,COG0187@1,COG0187@2	NA|NA|NA	L	DNA topoisomerase (ATP-hydrolyzing)
NIOIMGPL_00695	398513.BBNG_01213	6.3e-181	640.6	Bifidobacteriales	sigA			ko:K03086					ko00000,ko03021				Bacteria	2GK3Z@201174,4CZQC@85004,COG0568@1,COG0568@2	NA|NA|NA	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NIOIMGPL_00696	398513.BBNG_01214	1.7e-122	445.3	Bifidobacteriales													Bacteria	2B5AP@1,2IF9M@201174,31Y4U@2,4D15J@85004	NA|NA|NA		
NIOIMGPL_00697	702459.BBPR_1261	1.5e-200	705.3	Bifidobacteriales	crtE		2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006				Bacteria	2GJEK@201174,4CZQV@85004,COG0142@1,COG0142@2	NA|NA|NA	H	Belongs to the FPP GGPP synthase family
NIOIMGPL_00698	398513.BBNG_01216	0.0	1226.8	Bifidobacteriales	pknL		2.7.11.1	ko:K12132					ko00000,ko01000,ko01001				Bacteria	2GJ1J@201174,4CYTR@85004,COG0515@1,COG0515@2,COG2815@1,COG2815@2	NA|NA|NA	KLT	PASTA
NIOIMGPL_00699	398513.BBNG_01217	5.1e-133	480.3	Bifidobacteriales	plsC2		2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	2GJ6V@201174,4CZBB@85004,COG0204@1,COG0204@2	NA|NA|NA	I	Phosphate acyltransferases
NIOIMGPL_00700	702459.BBPR_1264	1.5e-109	402.1	Bifidobacteriales													Bacteria	2AP35@1,2IBUY@201174,31E4N@2,4D0R7@85004	NA|NA|NA		
NIOIMGPL_00701	702459.BBPR_1265	1.1e-192	679.1	Bifidobacteriales	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000				Bacteria	2GM4G@201174,4CZKZ@85004,COG0547@1,COG0547@2	NA|NA|NA	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NIOIMGPL_00702	398513.BBNG_01220	0.0	1816.6	Bifidobacteriales	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030312,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680		ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4			Bacteria	2GIRT@201174,4CYX6@85004,COG0653@1,COG0653@2	NA|NA|NA	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NIOIMGPL_00703	398513.BBNG_01221	2.8e-98	365.2	Bifidobacteriales	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113		ko:K05808					ko00000,ko03009				Bacteria	2GMYF@201174,4CZ3H@85004,COG1544@1,COG1544@2	NA|NA|NA	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NIOIMGPL_00705	702459.BBPR_1269	1.1e-86	325.9	Bifidobacteriales	recX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K03565					ko00000,ko03400				Bacteria	2INKM@201174,4D0Y4@85004,COG2137@1,COG2137@2	NA|NA|NA	S	Modulates RecA activity
NIOIMGPL_00706	702459.BBPR_1270	8e-216	756.1	Bifidobacteriales	recA	GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043142,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363		ko:K03553	ko03440,map03440	M00729			ko00000,ko00001,ko00002,ko03400				Bacteria	2GJ4P@201174,4CYYY@85004,COG0468@1,COG0468@2	NA|NA|NA	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NIOIMGPL_00707	398513.BBNG_01226	3.7e-40	170.2	Bifidobacteriales													Bacteria	2EFU9@1,2GQJW@201174,339KE@2,4D16T@85004	NA|NA|NA	S	Protein of unknown function (DUF3046)
NIOIMGPL_00708	398513.BBNG_01227	1.4e-79	302.4	Bifidobacteriales													Bacteria	2I2G5@201174,4D0PT@85004,COG1426@1,COG1426@2	NA|NA|NA	K	Helix-turn-helix XRE-family like proteins
NIOIMGPL_00709	398513.BBNG_01228	1.4e-37	162.2	Bifidobacteriales	cinA		3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760		R02322	RC00100	ko00000,ko00001,ko01000				Bacteria	2IQ8T@201174,4D0CM@85004,COG1546@1,COG1546@2	NA|NA|NA	S	Belongs to the CinA family
NIOIMGPL_00710	398513.BBNG_01229	4.5e-123	447.2	Bifidobacteriales	pgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100		R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000				Bacteria	2GK5D@201174,4CZ36@85004,COG0558@1,COG0558@2	NA|NA|NA	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NIOIMGPL_00711	702459.BBPR_1809	6.8e-144	516.5	Bifidobacteriales	cobB2			ko:K12410					ko00000,ko01000				Bacteria	2GJI3@201174,4CYUW@85004,COG0846@1,COG0846@2	NA|NA|NA	K	Sir2 family
NIOIMGPL_00712	398513.BBNG_01742	2.2e-234	818.1	Bifidobacteriales	tdcB	GO:0003674,GO:0003824,GO:0003941,GO:0004793,GO:0004794,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006565,GO:0006566,GO:0006567,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016597,GO:0016829,GO:0016830,GO:0016832,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000				Bacteria	2GJAG@201174,4CYW0@85004,COG1171@1,COG1171@2	NA|NA|NA	E	Pyridoxal-phosphate dependent enzyme
NIOIMGPL_00713	398513.BBNG_01743	3.1e-83	314.3	Bifidobacteriales	tadA		3.5.4.1,3.5.4.33,3.8.1.5,6.3.4.19	ko:K01485,ko:K01563,ko:K04075,ko:K11991	ko00240,ko00330,ko00361,ko00625,ko01100,ko01120,map00240,map00330,map00361,map00625,map01100,map01120		R00974,R01411,R02922,R05284,R05367,R05368,R05369,R05370,R07669,R07670,R09597,R10223	RC00074,RC00477,RC00514,RC00809,RC01317,RC01340,RC01341,RC02013,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016				Bacteria	2IM3Z@201174,4D0V0@85004,COG0590@1,COG0590@2	NA|NA|NA	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NIOIMGPL_00714	398513.BBNG_01744	4.4e-143	513.8	Bifidobacteriales	ypfH	GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0052689		ko:K06999					ko00000				Bacteria	2I5NR@201174,4CZJQ@85004,COG0400@1,COG0400@2	NA|NA|NA	S	Phospholipase/Carboxylesterase
NIOIMGPL_00715	398513.BBNG_01745	0.0	1191.8	Bifidobacteriales	yjcE	GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600		ko:K03316					ko00000	2.A.36			Bacteria	2GIUT@201174,4CZC4@85004,COG0025@1,COG0025@2	NA|NA|NA	P	Sodium/hydrogen exchanger family
NIOIMGPL_00716	398513.BBNG_01746	5.3e-112	410.2	Bifidobacteriales	dcd	GO:0003674,GO:0003824,GO:0004170,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0015949,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0033973,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000			iPC815.YPO1525	Bacteria	2GKQQ@201174,4CZEB@85004,COG0717@1,COG0717@2	NA|NA|NA	F	Belongs to the dCTP deaminase family
NIOIMGPL_00717	398513.BBNG_01747	0.0	1511.5	Bifidobacteriales			3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603		R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000				Bacteria	2GJJ1@201174,4CZJB@85004,COG3345@1,COG3345@2	NA|NA|NA	G	Glycosyl hydrolase family 36 N-terminal domain
NIOIMGPL_00718	398513.BBNG_01748	0.0	1823.9	Bifidobacteriales	pacL2		3.6.3.8	ko:K01537					ko00000,ko01000	3.A.3.2			Bacteria	2GJJC@201174,4CZ1I@85004,COG0474@1,COG0474@2	NA|NA|NA	P	Cation transporter/ATPase, N-terminus
NIOIMGPL_00720	398513.BBNG_01751	9.9e-175	619.4	Bifidobacteriales	rlmB	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218					ko00000,ko01000,ko03009				Bacteria	2GJMR@201174,4CZB1@85004,COG0566@1,COG0566@2	NA|NA|NA	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIOIMGPL_00721	702459.BBPR_1818	7.5e-269	932.6	Bifidobacteriales													Bacteria	2I2F0@201174,4CZ2E@85004,COG0515@1,COG0515@2	NA|NA|NA	KLT	Domain of unknown function (DUF4032)
NIOIMGPL_00722	702459.BBPR_1819	8.8e-43	179.5	Bifidobacteriales													Bacteria	2EUBW@1,2ICS5@201174,33MU8@2,4D08R@85004	NA|NA|NA		
NIOIMGPL_00723	326426.Bbr_1887	6.4e-87	326.6	Bifidobacteriales			3.4.22.70	ko:K07284					ko00000,ko01000,ko01002,ko01011				Bacteria	2GNWT@201174,4CZMM@85004,COG3764@1,COG3764@2	NA|NA|NA	M	Sortase family
NIOIMGPL_00724	326426.Bbr_1887	5e-57	227.3	Bifidobacteriales			3.4.22.70	ko:K07284					ko00000,ko01000,ko01002,ko01011				Bacteria	2GNWT@201174,4CZMM@85004,COG3764@1,COG3764@2	NA|NA|NA	M	Sortase family
NIOIMGPL_00725	398513.BBNG_01027	1.5e-74	285.4	Actinobacteria				ko:K06888					ko00000				Bacteria	2IKQP@201174,COG4405@1,COG4405@2	NA|NA|NA	I	ASCH
NIOIMGPL_00727	216816.GS08_05055	1.2e-68	265.8	Bifidobacteriales													Bacteria	2ATA8@1,2IICV@201174,31IT9@2,4D0W4@85004	NA|NA|NA		
NIOIMGPL_00729	398513.BBNG_01023	2.4e-43	181.4	Bifidobacteriales			2.7.7.1,3.6.1.13,3.6.1.55	ko:K01515,ko:K03207,ko:K03574,ko:K08311,ko:K13522	ko00230,ko00760,ko01100,ko03018,map00230,map00760,map01100,map03018		R00137,R01054,R03005,R10816	RC00002	ko00000,ko00001,ko01000,ko03019,ko03400				Bacteria	2I0XY@201174,4D08F@85004,COG1051@1,COG1051@2	NA|NA|NA	F	Hydrolase of X-linked nucleoside diphosphate N terminal
NIOIMGPL_00730	702459.BBPR_1097	1.1e-15	88.2	Bifidobacteriales				ko:K03496,ko:K22491					ko00000,ko03000,ko03036,ko04812				Bacteria	2HAHU@201174,4D2NY@85004,COG0789@1,COG0789@2	NA|NA|NA	K	Transcriptional regulator
NIOIMGPL_00731	398513.BBNG_01021	7.5e-91	339.7	Bifidobacteriales	MA20_25245												Bacteria	2HZQT@201174,4D1A5@85004,COG0454@1,COG0456@2	NA|NA|NA	K	FR47-like protein
NIOIMGPL_00732	702459.BBPR_1095	4.4e-120	437.2	Bifidobacteriales	ydaF_1												Bacteria	2HZBU@201174,4CZN2@85004,COG1670@1,COG1670@2	NA|NA|NA	J	Acetyltransferase (GNAT) domain
NIOIMGPL_00733	702459.BBPR_1094	1.5e-64	251.9	Bifidobacteriales	yeaO												Bacteria	2IQC0@201174,4D18P@85004,COG3189@1,COG3189@2	NA|NA|NA	K	Protein of unknown function, DUF488
NIOIMGPL_00734	702459.BBPR_1093	2.5e-163	581.3	Bifidobacteriales	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	2GJJQ@201174,4CZ0H@85004,COG0648@1,COG0648@2	NA|NA|NA	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NIOIMGPL_00735	702459.BBPR_1092	1.4e-284	984.9	Bifidobacteriales													Bacteria	2ETEZ@1,2HXGA@201174,33KYW@2,4CZSC@85004	NA|NA|NA	S	Psort location Cytoplasmic, score 8.87
NIOIMGPL_00736	702459.BBPR_1091	1.2e-61	243.4	Bifidobacteriales													Bacteria	2APK1@1,2IEAB@201174,31EP8@2,4D0C3@85004	NA|NA|NA	S	Domain of unknown function (DUF4194)
NIOIMGPL_00737	702459.BBPR_1090	0.0	2312.3	Bifidobacteriales													Bacteria	2GMIP@201174,4CYWR@85004,COG4913@1,COG4913@2	NA|NA|NA	S	Psort location Cytoplasmic, score 8.87
NIOIMGPL_00738	702459.BBPR_1089	3.9e-290	1003.4	Bifidobacteriales													Bacteria	2GK9N@201174,4D003@85004,COG2939@1,COG2939@2	NA|NA|NA	E	Serine carboxypeptidase
NIOIMGPL_00739	398513.BBNG_01013	4.6e-144	517.3	Bifidobacteriales			3.1.3.85,5.4.2.11,5.4.2.12	ko:K01834,ko:K15634,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147				Bacteria	2GJYU@201174,4CZI8@85004,COG0406@1,COG0406@2	NA|NA|NA	G	Phosphoglycerate mutase family
NIOIMGPL_00740	398513.BBNG_01012	3.7e-171	607.4	Bifidobacteriales	corA			ko:K03284					ko00000,ko02000	1.A.35.1,1.A.35.3			Bacteria	2HZ8V@201174,4CYWX@85004,COG0598@1,COG0598@2	NA|NA|NA	P	CorA-like Mg2+ transporter protein
NIOIMGPL_00741	702459.BBPR_1086	9.5e-164	582.8	Bifidobacteriales				ko:K10005	ko02010,map02010	M00233			ko00000,ko00001,ko00002,ko02000	3.A.1.3.9			Bacteria	2I9PU@201174,4D09U@85004,COG0834@1,COG0834@2	NA|NA|NA	ET	Bacterial periplasmic substrate-binding proteins
NIOIMGPL_00742	702459.BBPR_1085	0.0	2060.0	Bifidobacteriales	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029				Bacteria	2GJI1@201174,4CZHV@85004,COG0495@1,COG0495@2	NA|NA|NA	J	Belongs to the class-I aminoacyl-tRNA synthetase family
NIOIMGPL_00743	702459.BBPR_1084	2.4e-94	352.1	Bifidobacteriales	comEA		2.4.1.21	ko:K00703,ko:K02237,ko:K02238	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00429,M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko02044	3.A.11.1,3.A.11.2	GT5		Bacteria	2IQDC@201174,4D176@85004,COG1555@1,COG1555@2	NA|NA|NA	L	Helix-hairpin-helix motif
NIOIMGPL_00744	702459.BBPR_1083	0.0	1266.5	Bifidobacteriales	comE			ko:K02238		M00429			ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2			Bacteria	2GJGR@201174,4CZ6X@85004,COG0658@1,COG0658@2	NA|NA|NA	S	Competence protein
NIOIMGPL_00745	398513.BBNG_01007	1.1e-181	642.5	Bifidobacteriales	holA		2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	2GNMZ@201174,4CZ07@85004,COG1466@1,COG1466@2	NA|NA|NA	L	DNA polymerase III delta subunit
NIOIMGPL_00746	398513.BBNG_01006	1.2e-111	409.1	Bifidobacteriales	ydiB	GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.7.1.221,5.1.1.1	ko:K01775,ko:K06925,ko:K07102	ko00473,ko00520,ko01100,ko01502,map00473,map00520,map01100,map01502		R00401,R08968,R11024	RC00002,RC00078,RC00285	ko00000,ko00001,ko01000,ko01011,ko03016				Bacteria	2IKV2@201174,4D0PH@85004,COG0802@1,COG0802@2	NA|NA|NA	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE
NIOIMGPL_00747	702459.BBPR_1080	5.4e-161	573.5	Bifidobacteriales	yeaZ	GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:0140096,GO:1901360,GO:1901564	2.3.1.234	ko:K01409,ko:K14742			R10648	RC00070,RC00416	ko00000,ko01000,ko03016				Bacteria	2GMTM@201174,4D0A2@85004,COG1214@1,COG1214@2	NA|NA|NA	O	Glycoprotease family
NIOIMGPL_00748	398513.BBNG_01004	2.6e-103	381.3	Bifidobacteriales	rimI	GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017189,GO:0018193,GO:0018194,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564	2.3.1.128,2.3.1.234	ko:K01409,ko:K03789,ko:K14742			R10648	RC00070,RC00416	ko00000,ko01000,ko03009,ko03016				Bacteria	2IM9R@201174,4D0Q0@85004,COG0454@1,COG0456@2	NA|NA|NA	K	FR47-like protein
NIOIMGPL_00749	702459.BBPR_1078	1.4e-195	688.7	Bifidobacteriales	tsaD	GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564	2.3.1.234	ko:K01409,ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	R10648	RC00070,RC00416	ko00000,ko00001,ko00002,ko01000,ko02044,ko03016	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4			Bacteria	2GJ98@201174,4CZ0K@85004,COG0533@1,COG0533@2	NA|NA|NA	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NIOIMGPL_00751	702459.BBPR_1076	3.1e-131	474.9	Bifidobacteriales													Bacteria	2IQ64@201174,4D199@85004,COG0739@1,COG0739@2	NA|NA|NA	M	Peptidase family M23
NIOIMGPL_00752	398513.BBNG_01000	0.0	1201.0	Bifidobacteriales	fadD1		6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1			Bacteria	2GIXQ@201174,4CYYC@85004,COG1022@1,COG1022@2	NA|NA|NA	I	AMP-binding enzyme
NIOIMGPL_00753	398513.BBNG_00999	2.3e-274	951.0	Bifidobacteriales				ko:K10439,ko:K10546	ko02010,ko02030,map02010,map02030	M00212,M00216			ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.5			Bacteria	2HZAK@201174,4CZCR@85004,COG4213@1,COG4213@2	NA|NA|NA	G	ABC transporter substrate-binding protein
NIOIMGPL_00754	398513.BBNG_00998	3.3e-241	840.5	Bifidobacteriales	icd	GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	2GM3D@201174,4CZ8V@85004,COG0538@1,COG0538@2	NA|NA|NA	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family
NIOIMGPL_00755	398513.BBNG_00997	2.5e-200	704.5	Bifidobacteriales	guaB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	2GKVS@201174,4CZDK@85004,COG0516@1,COG0516@2	NA|NA|NA	F	IMP dehydrogenase family protein
NIOIMGPL_00756	398513.BBNG_00996	5.7e-91	340.1	Bifidobacteriales													Bacteria	2BGJW@1,2IR97@201174,32AI7@2,4D19G@85004	NA|NA|NA		
NIOIMGPL_00757	398513.BBNG_00995	4.7e-26	123.2	Bifidobacteriales	fadD3		6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1			Bacteria	2GIXQ@201174,4CYVD@85004,COG1022@1,COG1022@2	NA|NA|NA	I	long-chain-fatty acid CoA ligase
NIOIMGPL_00758	702459.BBPR_1070	0.0	1175.2	Bifidobacteriales	fadD3		6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1			Bacteria	2GIXQ@201174,4CYVD@85004,COG1022@1,COG1022@2	NA|NA|NA	I	long-chain-fatty acid CoA ligase
NIOIMGPL_00759	398513.BBNG_00994	1.7e-87	328.6	Bifidobacteriales	def		3.5.1.88	ko:K01462					ko00000,ko01000				Bacteria	2GJ87@201174,4CZ63@85004,COG0242@1,COG0242@2	NA|NA|NA	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NIOIMGPL_00760	398513.BBNG_00993	1.4e-145	522.3	Bifidobacteriales	rpsB	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02967	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	2GMYC@201174,4CZ96@85004,COG0052@1,COG0052@2	NA|NA|NA	J	Belongs to the universal ribosomal protein uS2 family
NIOIMGPL_00761	398513.BBNG_01077	2.4e-30	137.5	Bifidobacteriales													Bacteria	2FG1A@1,2IRY7@201174,347Y1@2,4D1MK@85004	NA|NA|NA		
NIOIMGPL_00762	398513.BBNG_01076	5.5e-118	430.3	Actinobacteria													Bacteria	2E89C@1,2I65F@201174,332N8@2	NA|NA|NA	S	Domain of unknown function (DUF4357)
NIOIMGPL_00763	702459.BBPR_1152	7.1e-186	656.4	Bifidobacteriales	hsdM		2.1.1.72	ko:K03427					ko00000,ko01000,ko02048				Bacteria	2GKAQ@201174,4CZNR@85004,COG0286@1,COG0286@2	NA|NA|NA	V	modification (methylase) protein of type I restriction-modification system K03427
NIOIMGPL_00764	398513.BBNG_01075	4.4e-92	344.0	Bifidobacteriales	hsdM		2.1.1.72	ko:K03427					ko00000,ko01000,ko02048				Bacteria	2GKAQ@201174,4CZNR@85004,COG0286@1,COG0286@2	NA|NA|NA	V	modification (methylase) protein of type I restriction-modification system K03427
NIOIMGPL_00765	398513.BBNG_01075	1.3e-171	609.0	Bifidobacteriales	hsdM		2.1.1.72	ko:K03427					ko00000,ko01000,ko02048				Bacteria	2GKAQ@201174,4CZNR@85004,COG0286@1,COG0286@2	NA|NA|NA	V	modification (methylase) protein of type I restriction-modification system K03427
NIOIMGPL_00766	445975.COLSTE_00480	8.2e-74	283.5	Coriobacteriia	hsdS		3.1.21.3	ko:K01154					ko00000,ko01000,ko02048				Bacteria	2HUXQ@201174,4CVYK@84998,COG0732@1,COG0732@2	NA|NA|NA	V	type I restriction modification DNA specificity domain
NIOIMGPL_00767	216816.GS08_07835	1e-94	352.8	Bifidobacteriales			3.6.4.12	ko:K03655	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	2GP7C@201174,4CZRD@85004,COG2865@1,COG2865@2	NA|NA|NA	K	Putative DNA-binding domain
NIOIMGPL_00768	702459.BBPR_1150	1.6e-139	502.3	Bifidobacteriales			3.6.4.12	ko:K03655	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	2GP7C@201174,4CZRD@85004,COG2865@1,COG2865@2	NA|NA|NA	K	Putative DNA-binding domain
NIOIMGPL_00769	702459.BBPR_1149	8.7e-236	822.8	Bifidobacteriales	hsdR		3.1.21.3	ko:K01153					ko00000,ko01000,ko02048				Bacteria	2HI69@201174,4CZER@85004,COG0610@1,COG0610@2	NA|NA|NA	V	Subunit R is required for both nuclease and ATPase activities, but not for modification
NIOIMGPL_00770	398513.BBNG_01072	0.0	1192.6	Bifidobacteriales	hsdR		3.1.21.3	ko:K01153					ko00000,ko01000,ko02048				Bacteria	2HI69@201174,4CZER@85004,COG0610@1,COG0610@2	NA|NA|NA	V	Subunit R is required for both nuclease and ATPase activities, but not for modification
NIOIMGPL_00771	702459.BBPR_1148	1.4e-281	974.9	Bifidobacteriales	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147			iJN678.argH	Bacteria	2GJ2A@201174,4CZ50@85004,COG0165@1,COG0165@2	NA|NA|NA	E	argininosuccinate lyase
NIOIMGPL_00772	702459.BBPR_1147	1e-107	396.0	Bifidobacteriales			6.1.1.14	ko:K01879,ko:K06950	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	2IFXP@201174,4D0P2@85004,COG1418@1,COG1418@2	NA|NA|NA	S	Metal dependent phosphohydrolases with conserved 'HD' motif.
NIOIMGPL_00773	398513.BBNG_01069	4.6e-143	513.8	Bifidobacteriales													Bacteria	2IA3M@201174,4CZY7@85004,COG4905@1,COG4905@2	NA|NA|NA	S	Putative ABC-transporter type IV
NIOIMGPL_00774	398513.BBNG_01068	5.4e-253	879.8	Bifidobacteriales	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029				Bacteria	2GJPR@201174,4CZKG@85004,COG0162@1,COG0162@2	NA|NA|NA	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NIOIMGPL_00777	398513.BBNG_01067	2.5e-153	548.5	Bifidobacteriales													Bacteria	2GKX5@201174,4CYXN@85004,COG0457@1,COG0457@2	NA|NA|NA	L	Tetratricopeptide repeat
NIOIMGPL_00778	702459.BBPR_1143	8.6e-190	669.5	Bifidobacteriales	yutF	GO:0000121,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009987,GO:0016042,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030145,GO:0042578,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0046434,GO:0046475,GO:0046486,GO:0046503,GO:0046872,GO:0046914,GO:0046983,GO:0050897,GO:0071704,GO:1901575	3.1.3.41	ko:K01101	ko00627,ko01120,map00627,map01120		R03024	RC00151	ko00000,ko00001,ko01000				Bacteria	2GK7V@201174,4CZ1Z@85004,COG0647@1,COG0647@2	NA|NA|NA	G	Haloacid dehalogenase-like hydrolase
NIOIMGPL_00780	702459.BBPR_1141	2.4e-136	491.5	Bifidobacteriales	tlyA	GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.226,2.1.1.227	ko:K06442					ko00000,ko01000,ko03009				Bacteria	2GJVT@201174,4CZSS@85004,COG1189@1,COG1189@2	NA|NA|NA	J	Ribosomal RNA large subunit methyltransferase J
NIOIMGPL_00781	702459.BBPR_1140	3.1e-103	381.3	Bifidobacteriales													Bacteria	2B0CX@1,2GR13@201174,31SQ3@2,4D1JN@85004	NA|NA|NA		
NIOIMGPL_00782	702459.BBPR_1139	6.8e-116	423.3	Bifidobacteriales	trkA			ko:K03499					ko00000,ko02000	2.A.38.1,2.A.38.4			Bacteria	2IA09@201174,4CZVT@85004,COG0569@1,COG0569@2	NA|NA|NA	P	TrkA-N domain
NIOIMGPL_00783	398513.BBNG_01061	3.5e-237	827.4	Bifidobacteriales	trkB			ko:K03498					ko00000,ko02000	2.A.38.1,2.A.38.4			Bacteria	2GKKS@201174,4CZH7@85004,COG0168@1,COG0168@2	NA|NA|NA	P	Cation transport protein
NIOIMGPL_00784	398513.BBNG_01060	7.3e-183	646.4	Bifidobacteriales	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100		R00104	RC00002,RC00078	ko00000,ko00001,ko01000				Bacteria	2GKM2@201174,4CYZ0@85004,COG0061@1,COG0061@2	NA|NA|NA	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NIOIMGPL_00785	398513.BBNG_01059	3.5e-292	1010.4	Bifidobacteriales	recN	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0030312,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360		ko:K03631,ko:K13582	ko04112,map04112				ko00000,ko00001,ko03400				Bacteria	2GIVG@201174,4CYYF@85004,COG0497@1,COG0497@2	NA|NA|NA	L	May be involved in recombinational repair of damaged DNA
NIOIMGPL_00786	398513.BBNG_01058	5.8e-123	446.8	Bifidobacteriales													Bacteria	2I362@201174,4CZ8D@85004,COG0637@1,COG0637@2	NA|NA|NA	S	Haloacid dehalogenase-like hydrolase
NIOIMGPL_00787	398513.BBNG_01057	3.7e-58	230.7	Bifidobacteriales				ko:K07978,ko:K07979					ko00000,ko03000				Bacteria	2IQEW@201174,4D152@85004,COG1725@1,COG1725@2	NA|NA|NA	K	helix_turn_helix gluconate operon transcriptional repressor
NIOIMGPL_00788	702459.BBPR_1133	3.8e-176	624.0	Bifidobacteriales				ko:K01990		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	2GRE8@201174,4CZBH@85004,COG1131@1,COG1131@2	NA|NA|NA	V	ATPases associated with a variety of cellular activities
NIOIMGPL_00789	702459.BBPR_1132	1e-123	449.5	Bifidobacteriales													Bacteria	2ARYF@1,2IK3T@201174,31HAF@2,4D0YH@85004	NA|NA|NA	S	ABC-2 family transporter protein
NIOIMGPL_00790	702459.BBPR_1131	4e-122	444.1	Bifidobacteriales													Bacteria	2B3RX@1,2IRDS@201174,31PYJ@2,4D16Y@85004	NA|NA|NA	S	ABC-2 family transporter protein
NIOIMGPL_00791	702459.BBPR_1130	6.6e-284	982.6	Bifidobacteriales	thrC		4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000			iHN637.CLJU_RS16355,iIT341.HP0098	Bacteria	2GIRY@201174,4CYS0@85004,COG0498@1,COG0498@2	NA|NA|NA	E	Threonine synthase N terminus
NIOIMGPL_00792	401473.BDP_1182	4.3e-91	340.5	Bifidobacteriales	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	2GKTC@201174,4CZD3@85004,COG0441@1,COG0441@2	NA|NA|NA	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NIOIMGPL_00793	398513.BBNG_00941	7.7e-143	513.1	Bifidobacteriales	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	2GKTC@201174,4CZD3@85004,COG0441@1,COG0441@2	NA|NA|NA	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NIOIMGPL_00794	398513.BBNG_00940	0.0	1873.6	Bifidobacteriales			3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110		GH20		Bacteria	2H28J@201174,4D1SA@85004,COG3525@1,COG3525@2	NA|NA|NA	M	Glycosyl hydrolase family 20, catalytic domain
NIOIMGPL_00795	398513.BBNG_00939	1e-131	476.1	Bifidobacteriales	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464											Bacteria	2GJ4G@201174,4CZ9X@85004,COG0217@1,COG0217@2	NA|NA|NA	K	transcriptional regulatory protein
NIOIMGPL_00796	398513.BBNG_00938	1.8e-99	368.6	Bifidobacteriales	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	2GJI5@201174,4CZ79@85004,COG0817@1,COG0817@2	NA|NA|NA	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NIOIMGPL_00798	702459.BBPR_1013	3.3e-104	384.4	Bifidobacteriales	ruvA	GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03550	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	2GN17@201174,4CZCE@85004,COG0632@1,COG0632@2	NA|NA|NA	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NIOIMGPL_00799	702459.BBPR_1012	1.8e-201	708.4	Bifidobacteriales	ruvB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	3.6.4.12	ko:K03551	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	2GJZF@201174,4CZGU@85004,COG2255@1,COG2255@2	NA|NA|NA	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NIOIMGPL_00800	702459.BBPR_1011	2.6e-44	184.9	Bifidobacteriales	yajC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944		ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2			Bacteria	2IKUJ@201174,4D139@85004,COG1862@1,COG1862@2	NA|NA|NA	U	Preprotein translocase subunit
NIOIMGPL_00801	398513.BBNG_00933	7.2e-101	373.2	Bifidobacteriales	apt	GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100		R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147				Bacteria	2IM7C@201174,4CZ9H@85004,COG0503@1,COG0503@2	NA|NA|NA	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NIOIMGPL_00802	702459.BBPR_1009	9.6e-225	785.8	Bifidobacteriales	sucC		6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000				Bacteria	2GKSB@201174,4CZCQ@85004,COG0045@1,COG0045@2	NA|NA|NA	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NIOIMGPL_00803	398513.BBNG_00931	1.9e-120	439.9	Bifidobacteriales	sucD	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000				Bacteria	2GK00@201174,4CYX1@85004,COG0074@1,COG0074@2	NA|NA|NA	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NIOIMGPL_00804	702459.BBPR_1007	5.8e-83	313.5	Bifidobacteriales		GO:0008150,GO:0040007											Bacteria	2EKVE@1,2HZ8H@201174,33EIZ@2,4CYRN@85004	NA|NA|NA		
NIOIMGPL_00805	702459.BBPR_1006	0.0	1076.2	Bifidobacteriales	purH	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147			iHN637.CLJU_RS04230,iJN678.purH	Bacteria	2GJWU@201174,4CZ3P@85004,COG0138@1,COG0138@2	NA|NA|NA	F	Bifunctional purine biosynthesis protein PurH
NIOIMGPL_00806	398513.BBNG_00928	5.7e-30	136.7	Bifidobacteriales													Bacteria	2AXAE@1,2IQKC@201174,31P9H@2,4D18B@85004	NA|NA|NA		
NIOIMGPL_00807	398513.BBNG_00927	4.1e-103	381.3	Bifidobacteriales	glpF			ko:K02440,ko:K06188					ko00000,ko02000	1.A.8,1.A.8.1,1.A.8.2			Bacteria	2HZ9W@201174,4CZ5Q@85004,COG0580@1,COG0580@2	NA|NA|NA	U	Belongs to the MIP aquaporin (TC 1.A.8) family
NIOIMGPL_00808	398513.BBNG_00926	6.3e-145	520.0	Bifidobacteriales	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183					ko00000,ko01000,ko03009				Bacteria	2GJ4N@201174,4CZGG@85004,COG1187@1,COG1187@2	NA|NA|NA	J	Belongs to the pseudouridine synthase RsuA family
NIOIMGPL_00809	398513.BBNG_00925	0.0	1382.9	Bifidobacteriales	der	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0030312,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0040007,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	1.1.1.399,1.1.1.95,2.7.4.25	ko:K00058,ko:K00945,ko:K03977	ko00240,ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00240,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020,M00052	R00158,R00512,R01513,R01665	RC00002,RC00031	ko00000,ko00001,ko00002,ko01000,ko03009,ko04147				Bacteria	2GJ8J@201174,4CYSE@85004,COG0283@1,COG0283@2,COG1160@1,COG1160@2	NA|NA|NA	F	GTPase that plays an essential role in the late steps of ribosome biogenesis
NIOIMGPL_00810	702459.BBPR_1001	0.0	1365.1	Bifidobacteriales	trpB	GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.48,4.2.1.20	ko:K01609,ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03508	RC00209,RC00210,RC00700,RC00701,RC00944,RC02868	ko00000,ko00001,ko00002,ko01000				Bacteria	2GM7Z@201174,4CZJW@85004,COG0133@1,COG0133@2,COG0134@1,COG0134@2	NA|NA|NA	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NIOIMGPL_00811	398513.BBNG_00923	1.3e-162	578.9	Bifidobacteriales	trpA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000				Bacteria	2GN6T@201174,4D0A3@85004,COG0159@1,COG0159@2	NA|NA|NA	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NIOIMGPL_00812	398513.BBNG_00922	1.3e-179	635.6	Bifidobacteriales	lgt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009249,GO:0009898,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576	2.1.1.199	ko:K03438,ko:K13292					ko00000,ko01000,ko03009				Bacteria	2GKSS@201174,4CYV8@85004,COG0682@1,COG0682@2	NA|NA|NA	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NIOIMGPL_00813	398513.BBNG_00921	6.3e-101	373.6	Bifidobacteriales	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000				Bacteria	2GJZ9@201174,4CYX0@85004,COG0036@1,COG0036@2	NA|NA|NA	G	Ribulose-phosphate 3-epimerase
NIOIMGPL_00814	398513.BBNG_00920	6.4e-41	172.9	Bifidobacteriales	hisE	GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.4.19,3.6.1.31,5.3.1.16	ko:K01523,ko:K01814,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037,R04640	RC00002,RC00945,RC01055	ko00000,ko00001,ko00002,ko01000			iECNA114_1301.ECNA114_0880,iECW_1372.ECW_m2186,iEKO11_1354.EKO11_1768,iSB619.SA_RS14110,iUMN146_1321.UM146_06665,iWFL_1372.ECW_m2186,iYO844.BSU34860	Bacteria	2IQ4D@201174,4D108@85004,COG0140@1,COG0140@2	NA|NA|NA	E	Phosphoribosyl-ATP pyrophosphohydrolase
NIOIMGPL_00815	398513.BBNG_00919	1.8e-156	558.5	Bifidobacteriales	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000				Bacteria	2GNAX@201174,4CZ66@85004,COG0040@1,COG0040@2	NA|NA|NA	F	ATP phosphoribosyltransferase
NIOIMGPL_00816	398513.BBNG_00918	1.8e-116	425.2	Bifidobacteriales	pgsA	GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100		R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000				Bacteria	2GM3F@201174,4CZGD@85004,COG0558@1,COG0558@2	NA|NA|NA	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NIOIMGPL_00817	398513.BBNG_00917	9e-173	612.8	Bifidobacteriales		GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944											Bacteria	2GMS5@201174,4CZ72@85004,COG3879@1,COG3879@2	NA|NA|NA	S	Bacterial protein of unknown function (DUF881)
NIOIMGPL_00818	398513.BBNG_00916	2.6e-31	141.4	Bifidobacteriales	sbp												Bacteria	2IKJW@201174,4D12G@85004,COG3856@1,COG3856@2	NA|NA|NA	S	Protein of unknown function (DUF1290)
NIOIMGPL_00819	398513.BBNG_00915	2.5e-84	318.2	Bifidobacteriales		GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944											Bacteria	2GJ3C@201174,4CYYH@85004,COG3879@1,COG3879@2	NA|NA|NA	S	Bacterial protein of unknown function (DUF881)
NIOIMGPL_00820	398513.BBNG_00915	6.7e-41	172.9	Bifidobacteriales		GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944											Bacteria	2GJ3C@201174,4CYYH@85004,COG3879@1,COG3879@2	NA|NA|NA	S	Bacterial protein of unknown function (DUF881)
NIOIMGPL_00821	398513.BBNG_00914	9.6e-74	282.7	Bifidobacteriales	garA												Bacteria	2GK99@201174,4D0R3@85004,COG1716@1,COG1716@2	NA|NA|NA	T	Inner membrane component of T3SS, cytoplasmic domain
NIOIMGPL_00822	702459.BBPR_0990	1.2e-118	432.6	Bifidobacteriales													Bacteria	2GM67@201174,4CZ0X@85004,COG0789@1,COG0789@2	NA|NA|NA	K	helix_turn_helix, mercury resistance
NIOIMGPL_00823	398513.BBNG_00912	1.9e-62	245.0	Bifidobacteriales													Bacteria	29TZI@1,2ISJH@201174,30F8H@2,4D0Z6@85004	NA|NA|NA		
NIOIMGPL_00825	398513.BBNG_00906	7.3e-143	513.1	Bifidobacteriales	pgp	GO:0003674,GO:0003824,GO:0004672,GO:0004713,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0071704,GO:0140096,GO:1901564	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130		R01334	RC00017	ko00000,ko00001,ko01000				Bacteria	2HFGX@201174,4CYSF@85004,COG0546@1,COG0546@2	NA|NA|NA	S	HAD-hyrolase-like
NIOIMGPL_00826	398513.BBNG_00905	3e-62	244.2	Bifidobacteriales	rbpA	GO:0001000,GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0043167,GO:0043169,GO:0043175,GO:0045893,GO:0045935,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141											Bacteria	2CNY9@1,2IMK6@201174,32SI2@2,4D0V5@85004	NA|NA|NA	K	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
NIOIMGPL_00827	398513.BBNG_00904	0.0	1577.8	Bifidobacteriales	helY	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575		ko:K03727					ko00000,ko01000				Bacteria	2GJEX@201174,4CZEC@85004,COG4581@1,COG4581@2	NA|NA|NA	L	DEAD DEAH box helicase
NIOIMGPL_00828	702459.BBPR_0978	4.9e-20	104.0	Bifidobacteriales													Bacteria	2B5BE@1,2IQT5@201174,31Y5K@2,4D17A@85004	NA|NA|NA		
NIOIMGPL_00829	566552.BIFCAT_00733	4.8e-267	926.8	Bifidobacteriales	pafB			ko:K13573					ko00000,ko03051				Bacteria	2I8M5@201174,4CZWF@85004,COG2378@1,COG2378@2	NA|NA|NA	K	WYL domain
NIOIMGPL_00830	1435051.BMOU_1062	2.4e-24	117.5	Bifidobacteriales	pafB			ko:K13573					ko00000,ko03051				Bacteria	2I8M5@201174,4CZWF@85004,COG2378@1,COG2378@2	NA|NA|NA	K	WYL domain
NIOIMGPL_00831	566552.BIFCAT_00732	6.9e-116	423.3	Bifidobacteriales	ugpA		2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000				Bacteria	2I2G3@201174,4CYTQ@85004,COG4284@1,COG4284@2	NA|NA|NA	G	UTP-glucose-1-phosphate uridylyltransferase
NIOIMGPL_00833	566552.BIFCAT_00729	5.5e-275	953.0	Bifidobacteriales	der	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0030312,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0040007,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	1.1.1.399,1.1.1.95,2.7.4.25	ko:K00058,ko:K00945,ko:K03977	ko00240,ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00240,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020,M00052	R00158,R00512,R01513,R01665	RC00002,RC00031	ko00000,ko00001,ko00002,ko01000,ko03009,ko04147				Bacteria	2GJ8J@201174,4CYSE@85004,COG0283@1,COG0283@2,COG1160@1,COG1160@2	NA|NA|NA	F	GTPase that plays an essential role in the late steps of ribosome biogenesis
NIOIMGPL_00834	702459.BBPR_1021	1.2e-248	865.5	Bifidobacteriales				ko:K06956					ko00000				Bacteria	2I862@201174,4D08P@85004,COG1823@1,COG1823@2	NA|NA|NA	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NIOIMGPL_00837	398513.BBNG_00943	5.8e-09	66.6	Bifidobacteriales													Bacteria	2CBMG@1,2INSH@201174,33XKX@2,4D123@85004	NA|NA|NA		
NIOIMGPL_00838	398513.BBNG_00943	1.8e-69	268.5	Bifidobacteriales													Bacteria	2CBMG@1,2INSH@201174,33XKX@2,4D123@85004	NA|NA|NA		
NIOIMGPL_00839	398513.BBNG_00943	1.2e-111	409.1	Bifidobacteriales													Bacteria	2CBMG@1,2INSH@201174,33XKX@2,4D123@85004	NA|NA|NA		
NIOIMGPL_00843	398513.BBNG_00944	2.8e-156	557.8	Bifidobacteriales				ko:K07184					ko00000				Bacteria	2GK10@201174,4CYSJ@85004,COG1938@1,COG1938@2	NA|NA|NA	S	PAC2 family
NIOIMGPL_00844	398513.BBNG_00945	6.6e-29	132.9	Bifidobacteriales	uppP		3.6.1.27	ko:K06153	ko00550,map00550		R05627	RC00002	ko00000,ko00001,ko01000,ko01011				Bacteria	2GJVG@201174,4CZ83@85004,COG1968@1,COG1968@2	NA|NA|NA	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NIOIMGPL_00845	398513.BBNG_00945	1.1e-124	452.6	Bifidobacteriales	uppP		3.6.1.27	ko:K06153	ko00550,map00550		R05627	RC00002	ko00000,ko00001,ko01000,ko01011				Bacteria	2GJVG@201174,4CZ83@85004,COG1968@1,COG1968@2	NA|NA|NA	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NIOIMGPL_00846	702459.BBPR_1025	6e-159	566.6	Bifidobacteriales													Bacteria	2GW7W@201174,4CZ4W@85004,COG3001@1,COG3001@2	NA|NA|NA	G	Fructosamine kinase
NIOIMGPL_00847	398513.BBNG_00947	1.9e-209	734.9	Bifidobacteriales	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944		ko:K03686					ko00000,ko03029,ko03110				Bacteria	2GK69@201174,4D03K@85004,COG0484@1,COG0484@2	NA|NA|NA	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NIOIMGPL_00848	702459.BBPR_1027	8.7e-94	349.7	Bifidobacteriales	hrcA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141		ko:K03705					ko00000,ko03000				Bacteria	2GKF5@201174,4CZK3@85004,COG1420@1,COG1420@2	NA|NA|NA	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NIOIMGPL_00849	398513.BBNG_00948	2.5e-52	211.5	Bifidobacteriales	hrcA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141		ko:K03705					ko00000,ko03000				Bacteria	2GKF5@201174,4CZK3@85004,COG1420@1,COG1420@2	NA|NA|NA	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NIOIMGPL_00850	398513.BBNG_00949	0.0	1413.3	Bifidobacteriales	tkt	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000				Bacteria	2GJ1K@201174,4CZ64@85004,COG0021@1,COG0021@2	NA|NA|NA	H	Belongs to the transketolase family
NIOIMGPL_00851	398513.BBNG_00950	1e-201	709.1	Bifidobacteriales	tal	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016832,GO:0044424,GO:0044464,GO:0097023	2.2.1.2	ko:K00616,ko:K08313,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000			iB21_1397.B21_03781,iEC042_1314.EC042_0914,iECBD_1354.ECBD_4077,iECB_1328.ECB_03832,iECD_1391.ECD_03832,iECH74115_1262.ECH74115_5407,iECSP_1301.ECSP_5016,iECs_1301.ECs4875,iEcHS_1320.EcHS_A4181,iG2583_1286.G2583_4758,iSBO_1134.SBO_0715,iSF_1195.SF0775,iSFxv_1172.SFxv_0845,iS_1188.S0818,iZ_1308.Z5501	Bacteria	2GMF9@201174,4CZ3J@85004,COG0176@1,COG0176@2	NA|NA|NA	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NIOIMGPL_00852	702459.BBPR_1030	3.1e-142	511.1	Bifidobacteriales	yoaK												Bacteria	2GKDV@201174,4CZC9@85004,COG3619@1,COG3619@2	NA|NA|NA	S	Protein of unknown function (DUF1275)
NIOIMGPL_00853	702459.BBPR_1031	3.4e-253	880.6	Bifidobacteriales	brnQ			ko:K03311					ko00000	2.A.26			Bacteria	2GNMD@201174,4CZIP@85004,COG1114@1,COG1114@2	NA|NA|NA	U	Component of the transport system for branched-chain amino acids
NIOIMGPL_00855	398513.BBNG_00955	2e-242	844.7	Bifidobacteriales	mepA_6												Bacteria	2GXXK@201174,4D04E@85004,COG0534@1,COG0534@2	NA|NA|NA	V	MatE
NIOIMGPL_00856	398513.BBNG_00956	8e-162	576.2	Bifidobacteriales													Bacteria	2HZYB@201174,4CZQW@85004,COG0561@1,COG0561@2	NA|NA|NA	S	Sucrose-6F-phosphate phosphohydrolase
NIOIMGPL_00857	398513.BBNG_00957	9.1e-178	629.4	Bifidobacteriales	ldh	GO:0003674,GO:0003824,GO:0004457,GO:0004459,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922		R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147				Bacteria	2IASS@201174,4CZRT@85004,COG0039@1,COG0039@2	NA|NA|NA	C	Belongs to the LDH MDH superfamily
NIOIMGPL_00858	398513.BBNG_00958	8e-33	146.0	Bifidobacteriales	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680		ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2			Bacteria	2GR31@201174,4D16U@85004,COG1314@1,COG1314@2	NA|NA|NA	U	Preprotein translocase SecG subunit
NIOIMGPL_00859	398513.BBNG_00959	3.7e-134	484.2	Bifidobacteriales	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	2GJXZ@201174,4CYSG@85004,COG0149@1,COG0149@2	NA|NA|NA	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NIOIMGPL_00860	398513.BBNG_00960	2e-222	778.1	Bifidobacteriales	pgk	GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	2GJC6@201174,4CZJ3@85004,COG0126@1,COG0126@2	NA|NA|NA	F	Phosphoglycerate kinase
NIOIMGPL_00861	398513.BBNG_00961	5.6e-124	450.3	Bifidobacteriales	whiA	GO:0008150,GO:0043937,GO:0050789,GO:0050793,GO:0065007		ko:K09762					ko00000				Bacteria	2GJZU@201174,4CYTD@85004,COG1481@1,COG1481@2	NA|NA|NA	K	May be required for sporulation
NIOIMGPL_00862	398513.BBNG_00962	1.5e-177	628.6	Bifidobacteriales	rapZ	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363		ko:K06958					ko00000,ko03019				Bacteria	2GMWB@201174,4CZ70@85004,COG1660@1,COG1660@2	NA|NA|NA	S	Displays ATPase and GTPase activities
NIOIMGPL_00863	702459.BBPR_1041	3e-181	641.0	Bifidobacteriales	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000			iNJ661.Rv2552c	Bacteria	2GPQQ@201174,4CZCM@85004,COG0169@1,COG0169@2	NA|NA|NA	E	Shikimate dehydrogenase substrate binding domain
NIOIMGPL_00864	398513.BBNG_00964	1.2e-70	272.3	Bifidobacteriales	uvrC	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016787,GO:0016788,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391		ko:K03703	ko03420,map03420				ko00000,ko00001,ko03400				Bacteria	2GIS4@201174,4CYVX@85004,COG0322@1,COG0322@2	NA|NA|NA	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NIOIMGPL_00865	702459.BBPR_1042	0.0	1219.5	Bifidobacteriales	uvrC	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016787,GO:0016788,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391		ko:K03703	ko03420,map03420				ko00000,ko00001,ko03400				Bacteria	2GIS4@201174,4CYVX@85004,COG0322@1,COG0322@2	NA|NA|NA	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NIOIMGPL_00866	398513.BBNG_00965	0.0	2009.2	Bifidobacteriales	uvrA	GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090		ko:K03701	ko03420,map03420				ko00000,ko00001,ko03400				Bacteria	2GJUV@201174,4CYRU@85004,COG0178@1,COG0178@2	NA|NA|NA	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NIOIMGPL_00867	702459.BBPR_1044	1.2e-77	296.2	Bifidobacteriales													Bacteria	2B5S6@1,2I02B@201174,31YMU@2,4D2QX@85004	NA|NA|NA		
NIOIMGPL_00869	398513.BBNG_00968	3.3e-118	431.0	Bifidobacteriales													Bacteria	2GKYV@201174,4D0I8@85004,COG0745@1,COG0745@2	NA|NA|NA	K	Transcriptional regulatory protein, C terminal
NIOIMGPL_00870	702459.BBPR_1047	2.5e-240	837.8	Bifidobacteriales	qseC	GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0042221,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K02484,ko:K07637,ko:K07643,ko:K07645,ko:K07649,ko:K07653,ko:K18351	ko01502,ko01503,ko02020,ko02024,map01502,map01503,map02020,map02024	M00444,M00451,M00453,M00457,M00460,M00651,M00658,M00709,M00721,M00722,M00723,M00724,M00744			ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022				Bacteria	2I436@201174,4D01R@85004,COG0642@1,COG0642@2	NA|NA|NA	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NIOIMGPL_00871	398513.BBNG_00970	1.7e-139	501.9	Bifidobacteriales	vanY		3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651			ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504				Bacteria	2IN2C@201174,4CZAQ@85004,COG1876@1,COG1876@2	NA|NA|NA	M	D-alanyl-D-alanine carboxypeptidase
NIOIMGPL_00872	398513.BBNG_00972	3.7e-301	1040.0	Bifidobacteriales	ybiT												Bacteria	2GKQ4@201174,4CYS2@85004,COG0488@1,COG0488@2	NA|NA|NA	S	ABC transporter
NIOIMGPL_00873	702459.BBPR_1050	7.2e-197	693.0	Bifidobacteriales	galE		5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000				Bacteria	2GMCW@201174,4CZDB@85004,COG1087@1,COG1087@2	NA|NA|NA	M	Belongs to the NAD(P)-dependent epimerase dehydratase family
NIOIMGPL_00874	702459.BBPR_1051	3.7e-306	1056.6	Bifidobacteriales	galT		2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000				Bacteria	2HNCF@201174,4CZT3@85004,COG4468@1,COG4468@2	NA|NA|NA	G	UDP-glucose--hexose-1-phosphate uridylyltransferase
NIOIMGPL_00875	398513.BBNG_00975	1.4e-206	725.3	Bifidobacteriales	mdsC		2.7.1.162,2.7.1.39	ko:K02204,ko:K13059	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771,R08962	RC00002,RC00017,RC00078	ko00000,ko00001,ko00002,ko01000				Bacteria	2I8JD@201174,4D06K@85004,COG2334@1,COG2334@2	NA|NA|NA	S	Phosphotransferase enzyme family
NIOIMGPL_00876	702459.BBPR_1053	1.4e-217	761.9	Bifidobacteriales													Bacteria	2GKMZ@201174,4CZUF@85004,COG1940@1,COG1940@2	NA|NA|NA	GK	ROK family
NIOIMGPL_00877	398513.BBNG_00977	4.3e-52	210.3	Bifidobacteriales			2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	2GZ27@201174,4CZII@85004,COG1940@1,COG1940@2	NA|NA|NA	GK	ROK family
NIOIMGPL_00878	398513.BBNG_00977	6.1e-72	276.9	Bifidobacteriales			2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	2GZ27@201174,4CZII@85004,COG1940@1,COG1940@2	NA|NA|NA	GK	ROK family
NIOIMGPL_00879	398513.BBNG_00979	1.4e-158	565.5	Bifidobacteriales	gnpA	GO:0003674,GO:0003824,GO:0004645,GO:0005975,GO:0008150,GO:0008152,GO:0016740,GO:0016757,GO:0016758,GO:0044238,GO:0050500,GO:0071704	2.4.1.211	ko:K15533					ko00000,ko01000				Bacteria	2GN2A@201174,4CYZB@85004,COG5426@1,COG5426@2	NA|NA|NA	S	Lacto-N-biose phosphorylase C-terminal domain
NIOIMGPL_00880	702459.BBPR_1055	8.3e-148	529.6	Bifidobacteriales	gnpA	GO:0003674,GO:0003824,GO:0004645,GO:0005975,GO:0008150,GO:0008152,GO:0016740,GO:0016757,GO:0016758,GO:0044238,GO:0050500,GO:0071704	2.4.1.211	ko:K15533					ko00000,ko01000				Bacteria	2GN2A@201174,4CYZB@85004,COG5426@1,COG5426@2	NA|NA|NA	S	Lacto-N-biose phosphorylase C-terminal domain
NIOIMGPL_00881	398513.BBNG_00980	5e-168	597.0	Bifidobacteriales				ko:K02026		M00207			ko00000,ko00002,ko02000	3.A.1.1			Bacteria	2GJPZ@201174,4CYV5@85004,COG0395@1,COG0395@2	NA|NA|NA	G	ABC transporter permease
NIOIMGPL_00882	702459.BBPR_1057	1.1e-173	615.9	Bifidobacteriales				ko:K02025,ko:K15771	ko02010,map02010	M00207,M00491			ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2			Bacteria	2GMTW@201174,4CZX2@85004,COG1175@1,COG1175@2	NA|NA|NA	G	Binding-protein-dependent transport system inner membrane component
NIOIMGPL_00883	702459.BBPR_1058	2.2e-243	847.8	Bifidobacteriales				ko:K02027		M00207			ko00000,ko00002,ko02000	3.A.1.1			Bacteria	2GJIP@201174,4CZ88@85004,COG1653@1,COG1653@2	NA|NA|NA	G	Bacterial extracellular solute-binding protein
NIOIMGPL_00884	702459.BBPR_1059	1.3e-309	1068.1	Bifidobacteriales	trpE		4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000				Bacteria	2GKJT@201174,4CZHW@85004,COG0147@1,COG0147@2	NA|NA|NA	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NIOIMGPL_00885	702459.BBPR_1060	5.3e-74	283.5	Bifidobacteriales	hisI	GO:0008150,GO:0040007	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000			iNJ661.Rv1606	Bacteria	2IKKU@201174,4D0WW@85004,COG0139@1,COG0139@2	NA|NA|NA	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NIOIMGPL_00886	398513.BBNG_00985	1.4e-139	502.3	Bifidobacteriales	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007	4.1.3.27	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023,M00026	R00985,R00986,R04558	RC00010,RC01190,RC01943,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000				Bacteria	2GIRP@201174,4CZ8Z@85004,COG0107@1,COG0107@2	NA|NA|NA	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NIOIMGPL_00887	702459.BBPR_1062	9.8e-230	802.4	Bifidobacteriales	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941					ko00000,ko01000,ko03009				Bacteria	2GJ48@201174,4CZG2@85004,COG0820@1,COG0820@2	NA|NA|NA	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NIOIMGPL_00888	398513.BBNG_00987	1.8e-176	625.2	Bifidobacteriales	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41,2.7.7.67	ko:K00981,ko:K07098,ko:K19664	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799,R08966	RC00002	ko00000,ko00001,ko00002,ko01000			iLJ478.TM1397	Bacteria	2I7ZA@201174,4CYZM@85004,COG0575@1,COG0575@2	NA|NA|NA	I	Cytidylyltransferase family
NIOIMGPL_00889	398513.BBNG_00988	2.4e-93	348.2	Bifidobacteriales	frr	GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576		ko:K02838					ko00000,ko03012				Bacteria	2GJ9J@201174,4CYTF@85004,COG0233@1,COG0233@2	NA|NA|NA	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NIOIMGPL_00890	398513.BBNG_00989	2.4e-133	481.5	Bifidobacteriales	pyrH	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100		R00158	RC00002	ko00000,ko00001,ko01000			iSB619.SA_RS06240	Bacteria	2GKWQ@201174,4CZEK@85004,COG0528@1,COG0528@2	NA|NA|NA	F	Catalyzes the reversible phosphorylation of UMP to UDP
NIOIMGPL_00891	702459.BBPR_1066	3.7e-37	160.2	Bifidobacteriales			3.2.1.8	ko:K01181,ko:K06889					ko00000,ko01000				Bacteria	2HZF3@201174,4D06X@85004,COG1073@1,COG1073@2	NA|NA|NA	S	alpha beta
NIOIMGPL_00892	398513.BBNG_00990	1.9e-69	268.5	Bifidobacteriales			3.2.1.8	ko:K01181,ko:K06889					ko00000,ko01000				Bacteria	2HZF3@201174,4D06X@85004,COG1073@1,COG1073@2	NA|NA|NA	S	alpha beta
NIOIMGPL_00893	398513.BBNG_00992	8.4e-31	139.0	Bifidobacteriales	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576		ko:K02357					ko00000,ko03012,ko03029				Bacteria	2GK4M@201174,4CYVQ@85004,COG0264@1,COG0264@2	NA|NA|NA	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NIOIMGPL_00894	1007096.BAGW01000029_gene1531	2.8e-16	92.0	Clostridia	kdgR	GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141		ko:K19333					ko00000,ko03000				Bacteria	1V2DI@1239,24BQR@186801,COG1414@1,COG1414@2	NA|NA|NA	K	transcriptional regulator
NIOIMGPL_00895	1378168.N510_02038	3.6e-33	147.9	Firmicutes	ebgC			ko:K12112	ko00052,ko00511,ko01100,map00052,map00511,map01100		R01678	RC00049	ko00000,ko00001				Bacteria	1VCI9@1239,COG2731@1,COG2731@2	NA|NA|NA	G	YhcH YjgK YiaL family
NIOIMGPL_00896	515620.EUBELI_00687	7.1e-07	62.4	Clostridia													Bacteria	1V1X0@1239,24H8Q@186801,28P23@1,2ZBY9@2	NA|NA|NA		
NIOIMGPL_00897	1282887.AUJG01000003_gene540	3e-46	191.8	Clostridia													Bacteria	1TP2R@1239,249PA@186801,COG4632@1,COG4632@2	NA|NA|NA	G	Exopolysaccharide biosynthesis protein
NIOIMGPL_00898	702459.BBPR_1129	3.8e-145	520.8	Bifidobacteriales	proA	GO:0003674,GO:0003824,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000			iLJ478.TM0293,iNJ661.Rv2427c,iYO844.BSU13130	Bacteria	2GISA@201174,4CZ2H@85004,COG0014@1,COG0014@2	NA|NA|NA	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NIOIMGPL_00899	398513.BBNG_01051	2.6e-92	344.7	Bifidobacteriales													Bacteria	2A13J@1,2GKGD@201174,30P9F@2,4D0QR@85004	NA|NA|NA		
NIOIMGPL_00900	702459.BBPR_1127	8.1e-145	519.6	Bifidobacteriales	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18,3.6.1.55	ko:K00969,ko:K03574	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400				Bacteria	2GMFZ@201174,4CZ82@85004,COG1057@1,COG1057@2	NA|NA|NA	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NIOIMGPL_00901	702459.BBPR_1126	9.1e-192	676.0	Bifidobacteriales	prs	GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000				Bacteria	2GJ9S@201174,4CYRD@85004,COG0462@1,COG0462@2	NA|NA|NA	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NIOIMGPL_00902	398513.BBNG_01048	1.2e-263	915.2	Bifidobacteriales	glmU	GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030203,GO:0030260,GO:0033692,GO:0034637,GO:0034645,GO:0035635,GO:0040007,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509	2.3.1.157,2.7.7.23	ko:K04042,ko:K11528,ko:K16203	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000,ko01002	3.A.1.5.2		iJN678.glmU,iLJ478.TM1629	Bacteria	2GJS1@201174,4CZ4C@85004,COG1207@1,COG1207@2	NA|NA|NA	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NIOIMGPL_00903	398513.BBNG_01047	9.3e-69	266.2	Bifidobacteriales	rsfS	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113	2.7.7.18	ko:K00969,ko:K09710	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000,ko03009				Bacteria	2IKZ3@201174,4D11U@85004,COG0799@1,COG0799@2	NA|NA|NA	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NIOIMGPL_00904	702459.BBPR_1123	1.9e-138	498.4	Bifidobacteriales			3.1.3.85,5.4.2.11,5.4.2.12	ko:K01834,ko:K15634,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147				Bacteria	2GJYU@201174,4CYXK@85004,COG0406@1,COG0406@2	NA|NA|NA	G	Phosphoglycerate mutase family
NIOIMGPL_00905	398513.BBNG_01045	1.3e-78	298.9	Bifidobacteriales													Bacteria	2IFD2@201174,4D0RX@85004,COG3428@1,COG3428@2	NA|NA|NA	S	Bacterial PH domain
NIOIMGPL_00906	398513.BBNG_01044	3.2e-255	887.1	Bifidobacteriales	nplT		3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973		R02108,R02112,R11262		ko00000,ko00001,ko01000		GH13		Bacteria	2GJUT@201174,4D075@85004,COG0366@1,COG0366@2	NA|NA|NA	G	Alpha amylase, catalytic domain
NIOIMGPL_00908	398513.BBNG_01043	1.2e-108	400.2	Bifidobacteriales													Bacteria	2DQFC@1,2I8B6@201174,336HV@2,4D309@85004	NA|NA|NA		
NIOIMGPL_00909	398513.BBNG_01042	2.5e-132	478.0	Bifidobacteriales													Bacteria	2GP9P@201174,4CZGH@85004,COG0778@1,COG0778@2	NA|NA|NA	C	Putative TM nitroreductase
NIOIMGPL_00910	702459.BBPR_1118	1e-141	509.6	Bifidobacteriales	yijF			ko:K09974					ko00000				Bacteria	2IBMJ@201174,4CZM2@85004,COG3738@1,COG3738@2	NA|NA|NA	S	Domain of unknown function (DUF1287)
NIOIMGPL_00911	398513.BBNG_01040	2.7e-70	271.2	Bifidobacteriales	pdxH			ko:K07006					ko00000				Bacteria	2IJK2@201174,4D0W8@85004,COG3576@1,COG3576@2	NA|NA|NA	S	Pfam:Pyridox_oxidase
NIOIMGPL_00912	398513.BBNG_01039	4.6e-146	523.9	Bifidobacteriales													Bacteria	2ISFD@201174,4D188@85004,COG0745@1,COG0745@2	NA|NA|NA	KT	RESPONSE REGULATOR receiver
NIOIMGPL_00913	702459.BBPR_1115	4.1e-192	677.2	Bifidobacteriales													Bacteria	2H595@201174,4CZBZ@85004,COG4767@1,COG4767@2	NA|NA|NA	V	VanZ like family
NIOIMGPL_00914	398513.BBNG_01037	2.3e-110	404.8	Bifidobacteriales	ycaK	GO:0000166,GO:0003674,GO:0005488,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0097159,GO:0097367,GO:1901265,GO:1901363	1.6.5.2	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418		R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000				Bacteria	2GNY7@201174,4D008@85004,COG2249@1,COG2249@2	NA|NA|NA	S	NADPH-dependent FMN reductase
NIOIMGPL_00915	702459.BBPR_1113	1.2e-97	362.5	Bifidobacteriales	ypjC												Bacteria	2H8Z8@201174,4D2DD@85004,COG4905@1,COG4905@2	NA|NA|NA	S	Putative ABC-transporter type IV
NIOIMGPL_00916	398513.BBNG_01035	5.7e-158	563.5	Bifidobacteriales													Bacteria	2IF0U@201174,4D0I9@85004,COG2865@1,COG2865@2	NA|NA|NA		
NIOIMGPL_00918	398513.BBNG_01033	1.6e-96	359.4	Bifidobacteriales				ko:K05820,ko:K08217					br01600,ko00000,ko01504,ko02000	2.A.1.21.1,2.A.1.21.22,2.A.1.27			Bacteria	2I2EY@201174,4D02G@85004,COG0477@1,COG2814@2	NA|NA|NA	EGP	Major facilitator Superfamily
NIOIMGPL_00919	398513.BBNG_01032	1.8e-151	542.0	Bifidobacteriales	rpoC												Bacteria	2GKXN@201174,4D079@85004,COG0739@1,COG0739@2	NA|NA|NA	M	heme binding
NIOIMGPL_00920	702459.BBPR_1106	2.5e-80	304.7	Bifidobacteriales	MA20_22310		4.4.1.5	ko:K01759	ko00620,map00620		R02530	RC00004,RC00740	ko00000,ko00001,ko01000				Bacteria	2II51@201174,4D0XJ@85004,COG0346@1,COG0346@2	NA|NA|NA	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NIOIMGPL_00921	702459.BBPR_1105	1.3e-125	455.7	Bifidobacteriales													Bacteria	2F5DW@1,2GVSX@201174,33XZS@2,4D292@85004	NA|NA|NA		
NIOIMGPL_00922	702459.BBPR_1104	4.7e-131	473.8	Bifidobacteriales													Bacteria	2GKY8@201174,4CZPW@85004,COG2135@1,COG2135@2	NA|NA|NA	S	SOS response associated peptidase (SRAP)
NIOIMGPL_00923	398513.BBNG_01028	1.9e-75	288.9	Bacteria	qseC	GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0042221,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K02484,ko:K07637,ko:K07643,ko:K07645,ko:K07649,ko:K07653,ko:K18351	ko01502,ko01503,ko02020,ko02024,map01502,map01503,map02020,map02024	M00444,M00451,M00453,M00457,M00460,M00651,M00658,M00709,M00721,M00722,M00723,M00724,M00744			ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022				Bacteria	COG0642@1,COG0642@2	NA|NA|NA	T	Histidine kinase
NIOIMGPL_00924	702459.BBPR_1101	1.4e-81	309.3	Bifidobacteriales				ko:K06888					ko00000				Bacteria	2HEQC@201174,4D0EK@85004,COG3981@1,COG3981@2,COG4405@1,COG4405@2	NA|NA|NA	S	Acetyltransferase (GNAT) domain
NIOIMGPL_00925	398513.BBNG_01852	6.8e-98	364.0	Bifidobacteriales				ko:K03646					ko00000,ko02000	2.C.1.2			Bacteria	2DDMI@1,2ICIR@201174,2ZIJN@2,4D112@85004	NA|NA|NA		
NIOIMGPL_00926	561180.BIFGAL_03249	0.0	1523.8	Bifidobacteriales	XK27_00515												Bacteria	2HRQY@201174,4CYQ9@85004,COG3087@1,COG3087@2	NA|NA|NA	D	Cell surface antigen C-terminus
NIOIMGPL_00927	1435051.BMOU_0855	5.2e-26	123.2	Bifidobacteriales													Bacteria	2EJJI@1,2GW42@201174,33DAG@2,4D1C7@85004	NA|NA|NA		
NIOIMGPL_00928	547043.BIFPSEUDO_03957	5.1e-95	354.0	Bifidobacteriales													Bacteria	2B0U3@1,2IDXF@201174,31T6M@2,4D095@85004	NA|NA|NA		
NIOIMGPL_00929	547043.BIFPSEUDO_03956	1.6e-63	248.4	Bifidobacteriales													Bacteria	29WJA@1,2IS86@201174,30I5I@2,4D16N@85004	NA|NA|NA	S	PrgI family protein
NIOIMGPL_00930	1435051.BMOU_0858	0.0	1261.1	Bifidobacteriales	trsE												Bacteria	2H6W2@201174,4CYWV@85004,COG3451@1,COG3451@2	NA|NA|NA	U	type IV secretory pathway VirB4
NIOIMGPL_00931	547043.BIFPSEUDO_03953	2.9e-206	724.9	Bifidobacteriales	isp2		3.2.1.96	ko:K01227,ko:K21471	ko00511,map00511				ko00000,ko00001,ko01000,ko01002,ko01011				Bacteria	2I9VT@201174,4D074@85004,COG0741@1,COG0741@2,COG3942@1,COG3942@2	NA|NA|NA	M	CHAP domain
NIOIMGPL_00932	1435051.BMOU_0860	3.6e-14	85.1	Bifidobacteriales				ko:K03205	ko03070,map03070	M00333			ko00000,ko00001,ko00002,ko02044	3.A.7			Bacteria	2HZ9D@201174,4CZ1V@85004,COG3505@1,COG3505@2	NA|NA|NA	U	Type IV secretory system Conjugative DNA transfer
NIOIMGPL_00933	547043.BIFPSEUDO_03951	3.3e-110	405.6	Bifidobacteriales				ko:K03646					ko00000,ko02000	2.C.1.2			Bacteria	2DDMI@1,2ICIR@201174,2ZIJN@2,4D112@85004	NA|NA|NA		
NIOIMGPL_00935	77635.BISU_1251	1.1e-100	373.6	Actinobacteria													Bacteria	2GRH0@201174,COG2856@1,COG2856@2	NA|NA|NA	K	Helix-turn-helix domain protein
NIOIMGPL_00937	547043.BIFPSEUDO_03950	1.8e-270	937.9	Bifidobacteriales				ko:K03205	ko03070,map03070	M00333			ko00000,ko00001,ko00002,ko02044	3.A.7			Bacteria	2HZ9D@201174,4CZ1V@85004,COG3505@1,COG3505@2	NA|NA|NA	U	Type IV secretory system Conjugative DNA transfer
NIOIMGPL_00938	398513.BBNG_00164	4.2e-33	146.7	Bifidobacteriales	dapE		3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000				Bacteria	2GK09@201174,4CZ9K@85004,COG0624@1,COG0624@2	NA|NA|NA	E	Peptidase dimerisation domain
NIOIMGPL_00939	702459.BBPR_0251	0.0	1315.4	Bifidobacteriales	rne	GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394			ko00000,ko00001,ko00002,ko01000,ko03009,ko03019				Bacteria	2GMM5@201174,4CYQT@85004,COG1530@1,COG1530@2	NA|NA|NA	J	Ribonuclease E/G family
NIOIMGPL_00940	398513.BBNG_00166	3.2e-47	194.1	Bifidobacteriales	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02888	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	2IQ9A@201174,4D10B@85004,COG0261@1,COG0261@2	NA|NA|NA	J	This protein binds to 23S rRNA in the presence of protein L20
NIOIMGPL_00941	398513.BBNG_00167	3.1e-40	170.6	Bifidobacteriales	rpmA	GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904		ko:K02899	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	2IQDI@201174,4D19N@85004,COG0211@1,COG0211@2	NA|NA|NA	J	Ribosomal L27 protein
NIOIMGPL_00942	702459.BBPR_0254	2.2e-215	754.6	Bifidobacteriales													Bacteria	2ICPH@201174,4CZJ7@85004,COG5340@1,COG5340@2	NA|NA|NA	K	Psort location Cytoplasmic, score
NIOIMGPL_00943	702459.BBPR_0255	4.8e-299	1033.1	Bifidobacteriales	obg	GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904		ko:K03979					ko00000,ko01000,ko03009				Bacteria	2GISB@201174,4CYWD@85004,COG0536@1,COG0536@2	NA|NA|NA	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NIOIMGPL_00944	398513.BBNG_00170	1.5e-200	705.3	Bifidobacteriales	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000				Bacteria	2GM8U@201174,4CZ2B@85004,COG0263@1,COG0263@2	NA|NA|NA	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NIOIMGPL_00945	398513.BBNG_00171	4e-231	807.0	Bifidobacteriales	aspC												Bacteria	2GJ7R@201174,4CZFY@85004,COG0436@1,COG0436@2	NA|NA|NA	E	DegT/DnrJ/EryC1/StrS aminotransferase family
NIOIMGPL_00947	702459.BBPR_0258	2.1e-32	144.4	Bifidobacteriales	secE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944		ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2			Bacteria	2HZQC@201174,4D18K@85004,COG0690@1,COG0690@2	NA|NA|NA	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NIOIMGPL_00948	702459.BBPR_0259	3.6e-109	401.4	Bifidobacteriales	nusG	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141		ko:K02601					ko00000,ko03009,ko03021				Bacteria	2GJFW@201174,4CYSH@85004,COG0250@1,COG0250@2	NA|NA|NA	K	Participates in transcription elongation, termination and antitermination
NIOIMGPL_00949	398513.BBNG_00174	1.5e-163	582.0	Bifidobacteriales	plsC2		2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	2GKVA@201174,4CZG0@85004,COG0204@1,COG0204@2	NA|NA|NA	I	Phosphate acyltransferases
NIOIMGPL_00950	398513.BBNG_00175	9.5e-178	629.4	Bifidobacteriales	gpsA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110		R00842,R00844	RC00029	ko00000,ko00001,ko01000				Bacteria	2GJSD@201174,4CZHP@85004,COG0240@1,COG0240@2	NA|NA|NA	I	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
NIOIMGPL_00951	398513.BBNG_00176	1.3e-218	765.4	Bifidobacteriales	ddl	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008716,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016874,GO:0016879,GO:0016881,GO:0044424,GO:0044444,GO:0044464,GO:0050896	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502		R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011			iAF1260.b0381,iB21_1397.B21_00332,iBWG_1329.BWG_0265,iE2348C_1286.E2348C_0317,iEC042_1314.EC042_0413,iEC55989_1330.EC55989_0386,iECBD_1354.ECBD_3283,iECB_1328.ECB_00328,iECDH10B_1368.ECDH10B_0338,iECDH1ME8569_1439.ECDH1ME8569_0367,iECD_1391.ECD_00328,iECH74115_1262.ECH74115_0453,iECIAI1_1343.ECIAI1_0377,iECIAI39_1322.ECIAI39_0301,iECO103_1326.ECO103_0356,iECO111_1330.ECO111_0411,iECO26_1355.ECO26_0414,iECSE_1348.ECSE_0401,iECSP_1301.ECSP_0441,iECs_1301.ECs0431,iETEC_1333.ETEC_0434,iEcDH1_1363.EcDH1_3227,iEcE24377_1341.EcE24377A_0406,iEcHS_1320.EcHS_A0447,iEcSMS35_1347.EcSMS35_0410,iEcolC_1368.EcolC_3251,iJO1366.b0381,iJR904.b0381,iSF_1195.SF0232,iSFxv_1172.SFxv_0245,iS_1188.S0254,iUMNK88_1353.UMNK88_429,iY75_1357.Y75_RS01965,iZ_1308.Z0477	Bacteria	2GITC@201174,4CZ1R@85004,COG1181@1,COG1181@2	NA|NA|NA	F	Belongs to the D-alanine--D-alanine ligase family
NIOIMGPL_00952	398513.BBNG_00177	3.7e-201	707.2	Bifidobacteriales	ugpQ		3.1.4.46	ko:K01126	ko00564,map00564		R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000				Bacteria	2GNM5@201174,4CYS4@85004,COG0584@1,COG0584@2	NA|NA|NA	C	Glycerophosphoryl diester phosphodiesterase family
NIOIMGPL_00953	398513.BBNG_00178	0.0	3571.6	Bifidobacteriales			3.2.1.97	ko:K02004,ko:K17624		M00258			ko00000,ko00002,ko01000,ko02000	3.A.1	GH101		Bacteria	2I615@201174,4CZVH@85004,COG0366@1,COG0366@2,COG1196@1,COG1196@2	NA|NA|NA	G	Glycosyl hydrolase 101 beta sandwich domain
NIOIMGPL_00954	398513.BBNG_00179	3.4e-191	674.1	Bifidobacteriales	prs	GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000				Bacteria	2GJ9S@201174,4CZPM@85004,COG0462@1,COG0462@2	NA|NA|NA	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NIOIMGPL_00955	398513.BBNG_00180	0.0	1456.0	Bifidobacteriales	ftsK		2.7.11.1,2.7.7.7,3.4.21.110,4.2.1.2	ko:K01679,ko:K02343,ko:K02519,ko:K03466,ko:K03591,ko:K03642,ko:K03749,ko:K05802,ko:K08652,ko:K12132,ko:K13733,ko:K14194,ko:K14195,ko:K18491,ko:K20382	ko00020,ko00230,ko00240,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02024,ko03030,ko03430,ko03440,ko04550,ko04934,ko05100,ko05150,ko05200,ko05211,map00020,map00230,map00240,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map02024,map03030,map03430,map03440,map04550,map04934,map05100,map05150,map05200,map05211	M00009,M00011,M00173,M00260,M00376	R00375,R00376,R00377,R00378,R01082	RC00443,RC02795	ko00000,ko00001,ko00002,ko01000,ko01001,ko01002,ko02000,ko03000,ko03012,ko03029,ko03032,ko03036,ko03110,ko03400	1.A.23.1.1,3.A.12			Bacteria	2IJPT@201174,4CYVI@85004,COG3087@1,COG3087@2	NA|NA|NA	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NIOIMGPL_00956	398513.BBNG_00181	3.1e-117	427.9	Bifidobacteriales													Bacteria	2F769@1,2IFMJ@201174,33ZMP@2,4D0UD@85004	NA|NA|NA		
NIOIMGPL_00957	702459.BBPR_0270	1.5e-163	582.8	Bifidobacteriales													Bacteria	2IBDZ@201174,4CYUA@85004,COG1520@1,COG1520@2,COG2114@1,COG2114@2	NA|NA|NA	T	Pfam Adenylate and Guanylate cyclase catalytic domain
NIOIMGPL_00958	398513.BBNG_00184	6.1e-48	196.4	Bifidobacteriales	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904		ko:K02990	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011,ko03029				Bacteria	2IQHD@201174,4D10X@85004,COG0360@1,COG0360@2	NA|NA|NA	J	Binds together with S18 to 16S ribosomal RNA
NIOIMGPL_00959	398513.BBNG_00185	1.1e-79	303.1	Bifidobacteriales	ssb1			ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440				ko00000,ko00001,ko03029,ko03032,ko03400				Bacteria	2GMM3@201174,4CZ5V@85004,COG0629@1,COG0629@2	NA|NA|NA	L	Single-stranded DNA-binding protein
NIOIMGPL_00960	398513.BBNG_00186	2e-36	157.9	Bifidobacteriales	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02963,ko:K03111,ko:K15125	ko03010,ko03030,ko03430,ko03440,ko05133,map03010,map03030,map03430,map03440,map05133	M00178			br01610,ko00000,ko00001,ko00002,ko00536,ko03011,ko03029,ko03032,ko03400				Bacteria	2IQ92@201174,4D103@85004,COG0238@1,COG0238@2	NA|NA|NA	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NIOIMGPL_00961	398513.BBNG_00187	6.6e-70	270.0	Bifidobacteriales	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02939	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	2IKX7@201174,4D0P9@85004,COG0359@1,COG0359@2	NA|NA|NA	J	Binds to the 23S rRNA
NIOIMGPL_00962	1437610.BREU_1938	5.2e-23	115.5	Bifidobacteriales													Bacteria	2DRF9@1,2I3CM@201174,33BGI@2,4D2ZK@85004	NA|NA|NA	S	Parallel beta-helix repeats
NIOIMGPL_00963	398513.BBNG_00189	1e-66	259.6	Actinobacteria													Bacteria	2GWES@201174,COG3227@1,COG3227@2	NA|NA|NA	E	Domain of unknown function (DUF5011)
NIOIMGPL_00965	398513.BBNG_00191	1.1e-130	472.6	Bifidobacteriales	gla			ko:K02440					ko00000,ko02000	1.A.8.1,1.A.8.2		iHN637.CLJU_RS07630	Bacteria	2GKK3@201174,4CZ7F@85004,COG0580@1,COG0580@2	NA|NA|NA	U	Belongs to the MIP aquaporin (TC 1.A.8) family
NIOIMGPL_00966	702459.BBPR_0278	3.9e-129	467.6	Bifidobacteriales													Bacteria	2GMJR@201174,4D0RU@85004,COG5479@1,COG5479@2	NA|NA|NA	M	Protein of unknown function (DUF3152)
NIOIMGPL_00967	398513.BBNG_00193	3.1e-186	657.5	Bifidobacteriales	gluQ		6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016				Bacteria	2GKMT@201174,4CYRY@85004,COG0008@1,COG0008@2	NA|NA|NA	J	Belongs to the class-I aminoacyl-tRNA synthetase family
NIOIMGPL_00968	702459.BBPR_0280	2.7e-146	524.6	Bifidobacteriales	yggS			ko:K06997					ko00000				Bacteria	2GMRJ@201174,4CZUY@85004,COG0325@1,COG0325@2	NA|NA|NA	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NIOIMGPL_00969	702459.BBPR_0281	3.6e-53	214.2	Bifidobacteriales	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120		R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000			iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036	Bacteria	2HZRI@201174,4D1EM@85004,COG1254@1,COG1254@2	NA|NA|NA	C	Acylphosphatase
NIOIMGPL_00970	702459.BBPR_0282	0.0	2207.2	Bifidobacteriales	inlJ			ko:K07114					ko00000,ko02000	1.A.13.2.2,1.A.13.2.3			Bacteria	2I2FM@201174,4CZ4I@85004,COG2304@1,COG2304@2,COG4932@1,COG4932@2	NA|NA|NA	M	domain protein
NIOIMGPL_00971	702459.BBPR_0283	1.1e-276	958.7	Bifidobacteriales													Bacteria	2GP68@201174,4CZV4@85004,COG4932@1,COG4932@2	NA|NA|NA	M	LPXTG cell wall anchor motif
NIOIMGPL_00972	702459.BBPR_0284	6.3e-213	746.5	Bifidobacteriales			3.4.22.70	ko:K07284					ko00000,ko01000,ko01002,ko01011				Bacteria	2GNWT@201174,4CZMM@85004,COG3764@1,COG3764@2	NA|NA|NA	M	Sortase family
NIOIMGPL_00973	702459.BBPR_0285	3.3e-72	279.3	Bifidobacteriales													Bacteria	29W7E@1,2HZTK@201174,30HSM@2,4D1PX@85004	NA|NA|NA	S	Domain of unknown function (DUF4854)
NIOIMGPL_00974	702459.BBPR_0286	4.2e-155	553.9	Bifidobacteriales	fahA												Bacteria	2GN2G@201174,4CZH5@85004,COG0179@1,COG0179@2	NA|NA|NA	Q	Fumarylacetoacetate (FAA) hydrolase family
NIOIMGPL_00975	641146.HMPREF9020_00431	1.9e-30	139.4	Bifidobacteriales			2.1.1.72	ko:K07316					ko00000,ko01000,ko02048				Bacteria	2GN40@201174,4CZPZ@85004,COG2852@1,COG2852@2	NA|NA|NA	S	Protein conserved in bacteria
NIOIMGPL_00976	702459.BBPR_0287	0.0	1689.1	Bifidobacteriales	clpB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944		ko:K03694,ko:K03695	ko04213,map04213				ko00000,ko00001,ko03110				Bacteria	2GJ73@201174,4CZDY@85004,COG0542@1,COG0542@2	NA|NA|NA	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NIOIMGPL_00977	398513.BBNG_00203	1.8e-131	475.3	Bifidobacteriales													Bacteria	2GZI1@201174,4CZ0A@85004,COG0668@1,COG0668@2	NA|NA|NA	M	Mechanosensitive ion channel
NIOIMGPL_00978	702459.BBPR_0289	3.8e-119	434.1	Bifidobacteriales													Bacteria	2I8SX@201174,4CZXQ@85004,COG1309@1,COG1309@2	NA|NA|NA	K	Bacterial regulatory proteins, tetR family
NIOIMGPL_00979	398513.BBNG_00205	2e-208	731.5	Bifidobacteriales	MA20_36090												Bacteria	2GMT6@201174,4CZ4Q@85004,COG1073@1,COG1073@2	NA|NA|NA	S	Psort location Cytoplasmic, score 8.87
NIOIMGPL_00980	398513.BBNG_00206	1.4e-231	808.5	Bifidobacteriales	yhdR		2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230		R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007				Bacteria	2GPM3@201174,4CZ6T@85004,COG0436@1,COG0436@2	NA|NA|NA	E	Psort location Cytoplasmic, score 8.87
NIOIMGPL_00981	702459.BBPR_0292	8.5e-66	257.7	Bifidobacteriales													Bacteria	2DBC0@1,2I65C@201174,2Z8BE@2,4D2Y9@85004	NA|NA|NA		
NIOIMGPL_00983	398513.BBNG_00210	7.2e-43	179.5	Bifidobacteriales													Bacteria	2GQY8@201174,4D1IJ@85004,COG3311@1,COG3311@2	NA|NA|NA	K	Transcriptional regulator
NIOIMGPL_00984	398513.BBNG_00211	0.0	1213.0	Bifidobacteriales	fadD		6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1			Bacteria	2GIXQ@201174,4CYYC@85004,COG1022@1,COG1022@2	NA|NA|NA	I	AMP-binding enzyme
NIOIMGPL_00986	398513.BBNG_00212	1.6e-32	144.8	Bifidobacteriales													Bacteria	29W7C@1,2H1A9@201174,30HSJ@2,4D1MJ@85004	NA|NA|NA		
NIOIMGPL_00991	702459.BBPR_0310	2.6e-132	478.0	Bifidobacteriales	tam	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0030798,GO:0032259,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0051704	2.1.1.144,2.1.1.197	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000			iECABU_c1320.ECABU_c17460,iSDY_1059.SDY_1625,ic_1306.c1942	Bacteria	2GJMG@201174,4CZKQ@85004,COG4106@1,COG4106@2	NA|NA|NA	S	Methyltransferase domain
NIOIMGPL_00992	398513.BBNG_00215	8.8e-226	789.3	Bifidobacteriales													Bacteria	2IBHI@201174,4CZ2T@85004,COG1476@1,COG1476@2	NA|NA|NA	K	Helix-turn-helix XRE-family like proteins
NIOIMGPL_00993	398513.BBNG_00216	3.2e-33	147.1	Bifidobacteriales			3.4.11.5	ko:K01259	ko00330,map00330		R00135		ko00000,ko00001,ko01000,ko01002				Bacteria	2IHR2@201174,4D1K6@85004,COG2267@1,COG2267@2	NA|NA|NA	I	carboxylic ester hydrolase activity
NIOIMGPL_00994	1680.BADO_1470	3.9e-190	670.6	Bifidobacteriales													Bacteria	2IF22@201174,4D0MK@85004,COG3677@1,COG3677@2	NA|NA|NA	L	Transposase
NIOIMGPL_00995	1680.BADO_1469	8.6e-21	105.5	Bifidobacteriales	relB			ko:K07473					ko00000,ko02048				Bacteria	2GRBT@201174,4D1GU@85004,COG3077@1,COG3077@2	NA|NA|NA	L	RelB antitoxin
NIOIMGPL_00996	313624.NSP_25570	5.6e-119	434.1	Nostocales	hpaIM		2.1.1.72	ko:K00571					ko00000,ko01000,ko02048				Bacteria	1G2XK@1117,1HU8N@1161,COG2189@1,COG2189@2	NA|NA|NA	L	Belongs to the N(4) N(6)-methyltransferase family
NIOIMGPL_00997	397288.C806_01412	3e-74	285.4	Bacteria													Bacteria	2DXH3@1,34505@2	NA|NA|NA		
NIOIMGPL_00998	398513.BBNG_00218	1.8e-53	214.9	Bifidobacteriales	relB			ko:K07473					ko00000,ko02048				Bacteria	2IJU2@201174,4D0WU@85004,COG3077@1,COG3077@2	NA|NA|NA	L	RelB antitoxin
NIOIMGPL_00999	216816.GS08_01645	5e-60	236.9	Bifidobacteriales													Bacteria	2IFQF@201174,4D0PF@85004,COG2337@1,COG2337@2	NA|NA|NA	T	Toxic component of a toxin-antitoxin (TA) module
NIOIMGPL_01000	702459.BBPR_0316	2e-132	478.4	Bifidobacteriales													Bacteria	2HZI3@201174,4D0I1@85004,COG0789@1,COG0789@2	NA|NA|NA	K	helix_turn_helix, mercury resistance
NIOIMGPL_01001	398513.BBNG_00222	4.3e-242	843.6	Bifidobacteriales	yxiO			ko:K06902	ko04138,map04138				ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1			Bacteria	2GJCW@201174,4CZU3@85004,COG2270@1,COG2270@2	NA|NA|NA	S	Vacuole effluxer Atg22 like
NIOIMGPL_01003	398513.BBNG_00224	6.5e-201	706.4	Bifidobacteriales	yegV	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704											Bacteria	2IA3T@201174,4CYSM@85004,COG0524@1,COG0524@2	NA|NA|NA	G	pfkB family carbohydrate kinase
NIOIMGPL_01004	398513.BBNG_00225	1.4e-29	134.8	Bifidobacteriales	rpmB	GO:0003674,GO:0003735,GO:0005198		ko:K02902	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	2GQNU@201174,4D17Q@85004,COG0227@1,COG0227@2	NA|NA|NA	J	Ribosomal L28 family
NIOIMGPL_01005	398513.BBNG_00226	0.0	1636.7	Bifidobacteriales	recG	GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494	3.6.4.12	ko:K03655	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	2GKA3@201174,4CYTV@85004,COG1200@1,COG1200@2	NA|NA|NA	L	helicase superfamily c-terminal domain
NIOIMGPL_01006	398513.BBNG_00227	7.2e-218	763.1	Bacteria	steT			ko:K03294					ko00000	2.A.3.2			Bacteria	COG0531@1,COG0531@2	NA|NA|NA	E	amino acid
NIOIMGPL_01008	702459.BBPR_0323	0.0	1083.2	Actinobacteria													Bacteria	2EEQH@1,2IDNM@201174,338I6@2	NA|NA|NA		
NIOIMGPL_01009	702459.BBPR_0324	5.1e-245	853.6	Bifidobacteriales				ko:K06956					ko00000				Bacteria	2GK6U@201174,4D301@85004,COG1301@1,COG1301@2	NA|NA|NA	U	Sodium:dicarboxylate symporter family
NIOIMGPL_01010	702459.BBPR_0325	6.8e-122	443.4	Bifidobacteriales	rsmD		2.1.1.171	ko:K08316			R07234	RC00003	ko00000,ko01000,ko03009				Bacteria	2GQ3G@201174,4D0GU@85004,COG0742@1,COG0742@2	NA|NA|NA	L	Conserved hypothetical protein 95
NIOIMGPL_01012	702459.BBPR_0326	4.1e-107	394.0	Bifidobacteriales	XK27_02070			ko:K07078					ko00000				Bacteria	2H12R@201174,4D072@85004,COG3560@1,COG3560@2	NA|NA|NA	S	Nitroreductase family
NIOIMGPL_01013	702459.BBPR_0327	8.3e-81	306.2	Bifidobacteriales	hsp20			ko:K13993	ko04141,map04141				ko00000,ko00001,ko03110				Bacteria	2HZHR@201174,4D0H9@85004,COG0071@1,COG0071@2	NA|NA|NA	O	Hsp20/alpha crystallin family
NIOIMGPL_01014	398513.BBNG_00234	1.4e-165	589.0	Bifidobacteriales	trmD	GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228,4.6.1.12	ko:K00554,ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R00597,R05637	RC00002,RC00003,RC00334,RC01440	ko00000,ko00001,ko00002,ko01000,ko03016				Bacteria	2GJ1G@201174,4CZ7A@85004,COG0336@1,COG0336@2	NA|NA|NA	J	Belongs to the RNA methyltransferase TrmD family
NIOIMGPL_01015	702459.BBPR_0329	1.3e-108	399.1	Bifidobacteriales	rimM	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360		ko:K02860					ko00000,ko03009				Bacteria	2GK4I@201174,4D0C6@85004,COG0806@1,COG0806@2	NA|NA|NA	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NIOIMGPL_01016	398513.BBNG_00236	1.8e-34	151.4	Bifidobacteriales	CP_0960	GO:0008150,GO:0040007		ko:K06960					ko00000				Bacteria	2IQ4C@201174,4D16Z@85004,COG1837@1,COG1837@2	NA|NA|NA	S	Belongs to the UPF0109 family
NIOIMGPL_01017	398513.BBNG_00237	1e-54	219.5	Bifidobacteriales	rpsP	GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02959	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011,ko03029				Bacteria	2IKU0@201174,4D0PE@85004,COG0228@1,COG0228@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bS16 family
NIOIMGPL_01018	702459.BBPR_0332	2.1e-280	971.1	Bifidobacteriales	ydfD			ko:K18907		M00700,M00702			ko00000,ko00002,ko01504,ko03000				Bacteria	2GITW@201174,4CZGJ@85004,COG1167@1,COG1167@2	NA|NA|NA	EK	Alanine-glyoxylate amino-transferase
NIOIMGPL_01019	398513.BBNG_00240	9.3e-82	310.1	Bifidobacteriales	argO	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015181,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902023,GO:1903825,GO:1903826,GO:1905039,GO:1990822		ko:K06895					ko00000,ko02000	2.A.75.1		iPC815.YPO0918	Bacteria	2HZBK@201174,4CZJP@85004,COG1279@1,COG1279@2	NA|NA|NA	S	LysE type translocator
NIOIMGPL_01020	702459.BBPR_0334	2.8e-221	774.2	Bifidobacteriales													Bacteria	2GK2H@201174,4CYS3@85004,COG3021@1,COG3021@2	NA|NA|NA	S	Endonuclease/Exonuclease/phosphatase family
NIOIMGPL_01021	398513.BBNG_00242	6.2e-215	753.4	Bifidobacteriales	ffh	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9			Bacteria	2GK4R@201174,4CYY1@85004,COG0541@1,COG0541@2	NA|NA|NA	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NIOIMGPL_01022	398513.BBNG_00244	4.2e-164	583.9	Bifidobacteriales													Bacteria	2H4CC@201174,4CZ1H@85004,COG3965@1,COG3965@2	NA|NA|NA	P	Cation efflux family
NIOIMGPL_01023	398513.BBNG_00246	0.0	1078.2	Bifidobacteriales	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	2GJF2@201174,4CZZ9@85004,COG0215@1,COG0215@2	NA|NA|NA	J	Belongs to the class-I aminoacyl-tRNA synthetase family
NIOIMGPL_01024	398513.BBNG_00247	2.3e-136	491.5	Bifidobacteriales	guaA1		6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002				Bacteria	2GNA6@201174,4CYR4@85004,COG0518@1,COG0518@2	NA|NA|NA	F	Peptidase C26
NIOIMGPL_01025	398513.BBNG_00248	0.0	1344.3	Bifidobacteriales	yjjK			ko:K15738					ko00000,ko02000	3.A.1.120.6			Bacteria	2GJ5M@201174,4CZCU@85004,COG0488@1,COG0488@2	NA|NA|NA	S	ABC transporter
NIOIMGPL_01026	398513.BBNG_00249	2e-58	231.5	Bifidobacteriales													Bacteria	2CAFG@1,2I800@201174,32ZDZ@2,4D107@85004	NA|NA|NA	S	Protein of unknown function (DUF3039)
NIOIMGPL_01027	702459.BBPR_0342	1.7e-81	308.5	Bifidobacteriales	coaD		2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000				Bacteria	2GN1S@201174,4CYR5@85004,COG0669@1,COG0669@2	NA|NA|NA	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NIOIMGPL_01028	702459.BBPR_0343	3.6e-107	394.8	Bifidobacteriales													Bacteria	2EKTZ@1,2HZD3@201174,33EHP@2,4CZV9@85004	NA|NA|NA		
NIOIMGPL_01029	398513.BBNG_00252	1e-113	416.0	Bifidobacteriales	yceD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464		ko:K07040					ko00000				Bacteria	2GJTS@201174,4CZ0J@85004,COG1399@1,COG1399@2	NA|NA|NA	S	Uncharacterized ACR, COG1399
NIOIMGPL_01030	398513.BBNG_00253	2.3e-19	100.9	Bifidobacteriales	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904		ko:K02911	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011,ko03029				Bacteria	2GQP3@201174,4D18N@85004,COG0333@1,COG0333@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL32 family
NIOIMGPL_01031	398513.BBNG_00254	1.8e-139	501.9	Bifidobacteriales	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205				ko00000,ko00001,ko01000,ko03009,ko03019,ko03036				Bacteria	2GKER@201174,4CZ98@85004,COG0571@1,COG0571@2	NA|NA|NA	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NIOIMGPL_01032	702459.BBPR_0347	0.0	1273.8	Bifidobacteriales	ilvB		2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000				Bacteria	2GKU4@201174,4CYR0@85004,COG0028@1,COG0028@2	NA|NA|NA	H	Thiamine pyrophosphate enzyme, central domain
NIOIMGPL_01033	398513.BBNG_00256	7.6e-92	343.2	Bifidobacteriales	ilvN	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000			iECO103_1326.ilvN,iJN678.ilvN	Bacteria	2GJCH@201174,4CYXX@85004,COG0440@1,COG0440@2	NA|NA|NA	E	ACT domain
NIOIMGPL_01036	702459.BBPR_0350	5.7e-247	859.8	Bifidobacteriales	pncB	GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0030312,GO:0034355,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100		R01724	RC00033	ko00000,ko00001,ko01000				Bacteria	2GJAT@201174,4CYUR@85004,COG1488@1,COG1488@2	NA|NA|NA	F	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NIOIMGPL_01037	398513.BBNG_00260	2.1e-134	485.0	Bifidobacteriales	rph	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575	2.7.7.56,3.6.1.66	ko:K00989,ko:K02428	ko00230,map00230		R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03016				Bacteria	2GJFI@201174,4CZBF@85004,COG0689@1,COG0689@2	NA|NA|NA	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NIOIMGPL_01038	398513.BBNG_00261	8.2e-117	426.4	Bifidobacteriales	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66,5.1.1.3	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100		R00260,R00426,R00720,R01855,R02100,R02720,R03531	RC00002,RC00302	ko00000,ko00001,ko01000,ko01011				Bacteria	2GM2B@201174,4CZ3F@85004,COG0127@1,COG0127@2	NA|NA|NA	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NIOIMGPL_01039	398513.BBNG_00262	5.4e-173	613.6	Bifidobacteriales				ko:K07088					ko00000				Bacteria	2GN0R@201174,4CZ6C@85004,COG0679@1,COG0679@2	NA|NA|NA	S	Auxin Efflux Carrier
NIOIMGPL_01042	398513.BBNG_00263	2.2e-141	508.4	Bifidobacteriales	pgi	GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	2GJG0@201174,4CYVV@85004,COG0166@1,COG0166@2	NA|NA|NA	G	Belongs to the GPI family
NIOIMGPL_01043	1437608.BBIA_0616	4.2e-91	340.9	Bifidobacteriales													Bacteria	2GMZX@201174,4D0DN@85004,COG2826@1,COG2826@2	NA|NA|NA	L	Transposase and inactivated derivatives IS30 family
NIOIMGPL_01044	398513.BBNG_01484	4.6e-168	597.0	Bifidobacteriales			1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120		R01708	RC00116	ko00000,ko00001,ko01000				Bacteria	2GJ6R@201174,4CZB6@85004,COG0667@1,COG0667@2	NA|NA|NA	C	Oxidoreductase, aldo keto reductase family protein
NIOIMGPL_01045	702459.BBPR_1622	2.2e-41	174.5	Bifidobacteriales	nrdH			ko:K06191					ko00000				Bacteria	2IRCP@201174,4D17U@85004,COG0695@1,COG0695@2	NA|NA|NA	O	Glutaredoxin
NIOIMGPL_01046	702459.BBPR_1623	1.5e-98	365.5	Bifidobacteriales	nrdI			ko:K03647					ko00000				Bacteria	2IM4D@201174,4D0XV@85004,COG1780@1,COG1780@2	NA|NA|NA	F	Probably involved in ribonucleotide reductase function
NIOIMGPL_01047	702459.BBPR_1624	0.0	1454.5	Bifidobacteriales	nrdE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0015949,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990204	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400			iAPECO1_1312.APECO1_3846,iYO844.BSU17380	Bacteria	2GKX9@201174,4CZF3@85004,COG0209@1,COG0209@2	NA|NA|NA	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NIOIMGPL_01048	702459.BBPR_1625	1.2e-188	665.6	Bifidobacteriales	nrdF	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0030145,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990204	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400			iECNA114_1301.ECNA114_2708,iECSF_1327.ECSF_2473,iSFV_1184.SFV_2827,iSF_1195.SF2704,iSFxv_1172.SFxv_2966,iS_1188.S2890	Bacteria	2GK46@201174,4CYQ2@85004,COG0208@1,COG0208@2	NA|NA|NA	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NIOIMGPL_01049	762211.BSTEL_0022	1.3e-73	282.3	Bifidobacteriales	megL		2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8	ko:K01739,ko:K01758,ko:K01760,ko:K01761	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00654,R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	2GNZH@201174,4D04I@85004,COG0626@1,COG0626@2	NA|NA|NA	E	Cys/Met metabolism PLP-dependent enzyme
NIOIMGPL_01050	702459.BBPR_1627	0.0	1398.6	Bifidobacteriales													Bacteria	2HZD2@201174,4CZV5@85004,COG4907@1,COG4907@2	NA|NA|NA	S	Predicted membrane protein (DUF2207)
NIOIMGPL_01051	398513.BBNG_01477	1e-91	342.8	Bifidobacteriales	lemA			ko:K03744					ko00000				Bacteria	2GPS4@201174,4CZE2@85004,COG1704@1,COG1704@2	NA|NA|NA	S	LemA family
NIOIMGPL_01052	398513.BBNG_01476	7.2e-116	423.7	Bacteria	xylR	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141		ko:K02529					ko00000,ko03000				Bacteria	COG1609@1,COG1609@2	NA|NA|NA	K	purine nucleotide biosynthetic process
NIOIMGPL_01053	398513.BBNG_01474	0.0	1503.8	Bifidobacteriales	pnp	GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019				Bacteria	2GIT2@201174,4CYSW@85004,COG1185@1,COG1185@2	NA|NA|NA	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NIOIMGPL_01054	398513.BBNG_01472	3e-41	174.1	Bifidobacteriales	rpsO	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02956	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	2IQA0@201174,4D10E@85004,COG0184@1,COG0184@2	NA|NA|NA	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NIOIMGPL_01055	702459.BBPR_1634	8.9e-119	433.0	Bifidobacteriales													Bacteria	2B37S@1,2IDBE@201174,31VVT@2,4CZJV@85004	NA|NA|NA		
NIOIMGPL_01056	702459.BBPR_1635	0.0	2094.7	Actinobacteria	nagH		3.2.1.35,3.2.1.52	ko:K01197,ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00076,M00077,M00079	R00022,R06004,R07824,R07825,R10905,R11316	RC00049	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042,ko03110		GH20		Bacteria	2GM4H@201174,COG3525@1,COG3525@2	NA|NA|NA	G	beta-N-acetylglucosaminidase
NIOIMGPL_01058	398513.BBNG_01469	1.3e-162	578.9	Bifidobacteriales	birA	GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837	2.7.1.33,6.3.4.15	ko:K01947,ko:K03524	ko00770,ko00780,ko01100,map00770,map00780,map01100	M00120	R01074,R02971,R03018,R04391,R05145	RC00002,RC00017,RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko00002,ko01000,ko03000				Bacteria	2GN8Q@201174,4D0R8@85004,COG0340@1,COG0340@2	NA|NA|NA	H	Biotin/lipoate A/B protein ligase family
NIOIMGPL_01059	702459.BBPR_1637	3.2e-98	364.4	Bifidobacteriales	acpS	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576	2.7.8.7,3.2.1.52	ko:K00997,ko:K01207	ko00520,ko00531,ko00770,ko01100,ko01501,map00520,map00531,map00770,map01100,map01501	M00628	R00022,R01625,R05963,R07809,R07810,R10831	RC00002,RC00049	ko00000,ko00001,ko00002,ko01000				Bacteria	2HZNB@201174,4D10J@85004,COG0736@1,COG0736@2	NA|NA|NA	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NIOIMGPL_01060	702459.BBPR_1638	0.0	6018.3	Bifidobacteriales	fas		2.3.1.179	ko:K09458,ko:K11533	ko00061,ko00780,ko01100,ko01212,ko04931,map00061,map00780,map01100,map01212,map04931	M00082,M00083,M00572	R01624,R01626,R04355,R04428,R04429,R04533,R04534,R04535,R04536,R04537,R04543,R04544,R04566,R04568,R04724,R04726,R04952,R04953,R04954,R04955,R04957,R04958,R04960,R04961,R04963,R04964,R04965,R04966,R04968,R04969,R07762,R07763,R07764,R07765,R10115,R10119,R10700	RC00004,RC00029,RC00039,RC00052,RC00076,RC00117,RC00831,RC01095,RC02727,RC02728,RC02729,RC02857,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	2GIY4@201174,4CYXJ@85004,COG0304@1,COG0304@2,COG0331@1,COG0331@2,COG2030@1,COG2030@2,COG4981@1,COG4981@2	NA|NA|NA	I	Beta-ketoacyl synthase, C-terminal domain
NIOIMGPL_01061	702459.BBPR_1639	7.2e-308	1062.4	Bifidobacteriales	pccB												Bacteria	2GIRU@201174,4CYSI@85004,COG4799@1,COG4799@2	NA|NA|NA	I	Carboxyl transferase domain
NIOIMGPL_01062	398513.BBNG_01465	0.0	1257.7	Bifidobacteriales	accA		6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000				Bacteria	2GIZP@201174,4CYU4@85004,COG4770@1,COG4770@2	NA|NA|NA	I	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
NIOIMGPL_01063	398513.BBNG_01464	2.1e-92	345.1	Bifidobacteriales	bioY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K03523	ko02010,map02010	M00581,M00582			ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2			Bacteria	2GJ53@201174,4D0BB@85004,COG1268@1,COG1268@2	NA|NA|NA	S	BioY family
NIOIMGPL_01064	398513.BBNG_01463	1.3e-151	542.3	Bifidobacteriales	birA	GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837	2.7.1.33,6.3.4.15	ko:K01947,ko:K03524	ko00770,ko00780,ko01100,map00770,map00780,map01100	M00120	R01074,R02971,R03018,R04391,R05145	RC00002,RC00017,RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko00002,ko01000,ko03000				Bacteria	2GN8Q@201174,4D0R8@85004,COG0340@1,COG0340@2	NA|NA|NA	H	Biotin/lipoate A/B protein ligase family
NIOIMGPL_01065	398513.BBNG_01462	0.0	1347.0	Bifidobacteriales													Bacteria	2DX0J@1,2H683@201174,342TV@2,4CZAG@85004	NA|NA|NA		
NIOIMGPL_01066	398513.BBNG_01461	5.9e-146	523.5	Bifidobacteriales													Bacteria	2GN0S@201174,4CYXU@85004,COG2508@1,COG2508@2	NA|NA|NA	QT	PucR C-terminal helix-turn-helix domain
NIOIMGPL_01067	702459.BBPR_1645	1.5e-129	468.8	Bifidobacteriales	nucS			ko:K07503					ko00000,ko01000				Bacteria	2GIYB@201174,4CYXA@85004,COG1637@1,COG1637@2	NA|NA|NA	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
NIOIMGPL_01068	702459.BBPR_1646	8.7e-50	202.6	Bifidobacteriales	atpC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600		ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194	3.A.2.1			Bacteria	2HZPJ@201174,4D16F@85004,COG0355@1,COG0355@2	NA|NA|NA	C	Produces ATP from ADP in the presence of a proton gradient across the membrane
NIOIMGPL_01069	398513.BBNG_01457	1.5e-283	981.5	Bifidobacteriales	atpD	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1			Bacteria	2GIY6@201174,4CZGY@85004,COG0055@1,COG0055@2	NA|NA|NA	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NIOIMGPL_01070	398513.BBNG_01456	6e-166	590.1	Bifidobacteriales	atpG	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600		ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194	3.A.2.1		iLJ478.TM1611,iSSON_1240.SSON_3886,iYL1228.KPN_04138	Bacteria	2GJ7Q@201174,4CYVJ@85004,COG0224@1,COG0224@2	NA|NA|NA	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NIOIMGPL_01071	398513.BBNG_01455	0.0	1105.1	Bifidobacteriales	atpA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1		iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187	Bacteria	2GJRJ@201174,4CZI7@85004,COG0056@1,COG0056@2	NA|NA|NA	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NIOIMGPL_01072	702459.BBPR_1650	1.4e-150	538.9	Bifidobacteriales	atpH			ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194	3.A.2.1			Bacteria	2GMJ5@201174,4CZ9V@85004,COG0712@1,COG0712@2	NA|NA|NA	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NIOIMGPL_01073	398513.BBNG_01453	4.6e-62	244.2	Bifidobacteriales	atpF			ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194	3.A.2.1			Bacteria	2GJS4@201174,4CYY5@85004,COG0711@1,COG0711@2	NA|NA|NA	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NIOIMGPL_01074	398513.BBNG_01452	1.2e-30	138.7	Bifidobacteriales	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600		ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194	3.A.2.1			Bacteria	2GQI6@201174,4D16J@85004,COG0636@1,COG0636@2	NA|NA|NA	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NIOIMGPL_01076	398513.BBNG_01451	6e-146	523.5	Bifidobacteriales	atpB			ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1			Bacteria	2H3PR@201174,4CYZD@85004,COG0356@1,COG0356@2	NA|NA|NA	C	it plays a direct role in the translocation of protons across the membrane
NIOIMGPL_01077	398513.BBNG_01450	3.5e-207	727.2	Bifidobacteriales	metAA	GO:0003674,GO:0003824,GO:0008374,GO:0008899,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000			iLJ478.TM0881	Bacteria	2GK5E@201174,4CZRK@85004,COG1897@1,COG1897@2	NA|NA|NA	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NIOIMGPL_01079	398513.BBNG_01447	3e-34	150.6	Bifidobacteriales													Bacteria	2E3TC@1,2GU2H@201174,32DPP@2,4D1HW@85004	NA|NA|NA		
NIOIMGPL_01080	702459.BBPR_1657	0.0	1428.3	Bifidobacteriales													Bacteria	2H7AK@201174,4CZMA@85004,COG5624@1,COG5624@2	NA|NA|NA	K	RNA polymerase II activating transcription factor binding
NIOIMGPL_01081	702459.BBPR_1658	0.0	1453.7	Bifidobacteriales	glgE		2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100		R09994		ko00000,ko00001,ko01000		GH13		Bacteria	2GJKR@201174,4CZSK@85004,COG0366@1,COG0366@2	NA|NA|NA	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
NIOIMGPL_01082	398513.BBNG_01444	5.2e-92	343.6	Bifidobacteriales	ppa	GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944	3.6.1.1	ko:K01507	ko00190,map00190				ko00000,ko00001,ko01000			iNJ661.Rv3628	Bacteria	2GM7F@201174,4CYWS@85004,COG0221@1,COG0221@2	NA|NA|NA	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NIOIMGPL_01084	702459.BBPR_1660	2.7e-100	371.3	Bifidobacteriales	mntP												Bacteria	2GNBU@201174,4D01X@85004,COG1971@1,COG1971@2	NA|NA|NA	P	Probably functions as a manganese efflux pump
NIOIMGPL_01085	398513.BBNG_01442	1.4e-125	455.7	Bifidobacteriales													Bacteria	2A0I6@1,2GJ8M@201174,30NNB@2,4D0ZN@85004	NA|NA|NA		
NIOIMGPL_01086	398513.BBNG_01441	1.5e-132	478.8	Bifidobacteriales													Bacteria	2GJGU@201174,4CZB9@85004,COG0745@1,COG0745@2	NA|NA|NA	KT	Transcriptional regulatory protein, C terminal
NIOIMGPL_01087	398513.BBNG_01440	3e-127	461.1	Bifidobacteriales	nth	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	4.2.99.18	ko:K10773	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	2GJ01@201174,4CZ31@85004,COG0177@1,COG0177@2	NA|NA|NA	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NIOIMGPL_01088	398513.BBNG_01439	9.6e-294	1015.4	Bifidobacteriales				ko:K02035	ko02024,map02024	M00239			ko00000,ko00001,ko00002,ko02000	3.A.1.5			Bacteria	2GM5G@201174,4CYUZ@85004,COG0747@1,COG0747@2	NA|NA|NA	E	Bacterial extracellular solute-binding proteins, family 5 Middle
NIOIMGPL_01089	398513.BBNG_01438	0.0	1884.0	Bifidobacteriales	valS		6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	2GK8H@201174,4CYVG@85004,COG0525@1,COG0525@2	NA|NA|NA	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NIOIMGPL_01090	702459.BBPR_1666	0.0	1162.5	Bifidobacteriales				ko:K01421,ko:K21449					ko00000,ko02000	1.B.40.2			Bacteria	2I9PN@201174,4CZC2@85004,COG1511@1,COG1511@2	NA|NA|NA	S	domain protein
NIOIMGPL_01091	398513.BBNG_01436	4.7e-73	280.4	Bifidobacteriales	tyrA		5.4.99.5	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000				Bacteria	2IQ46@201174,4D12A@85004,COG1605@1,COG1605@2	NA|NA|NA	E	Chorismate mutase type II
NIOIMGPL_01092	702459.BBPR_1668	2.4e-90	338.2	Bifidobacteriales	lrp_3			ko:K03719					ko00000,ko03000,ko03036				Bacteria	2GK3G@201174,4D0XT@85004,COG1522@1,COG1522@2	NA|NA|NA	K	helix_turn_helix ASNC type
NIOIMGPL_01093	702459.BBPR_1669	1.5e-233	815.1	Bifidobacteriales				ko:K10907					ko00000,ko01000,ko01007				Bacteria	2GJ7R@201174,4CYVP@85004,COG0436@1,COG0436@2	NA|NA|NA	E	Aminotransferase class I and II
NIOIMGPL_01094	702459.BBPR_1670	4.3e-305	1053.5	Bifidobacteriales	rho	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576		ko:K03628	ko03018,map03018				ko00000,ko00001,ko03019,ko03021				Bacteria	2GIWY@201174,4CZ2Z@85004,COG1158@1,COG1158@2	NA|NA|NA	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NIOIMGPL_01095	702459.BBPR_1672	8.2e-136	489.6	Bifidobacteriales			5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520		R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000				Bacteria	2HZ9K@201174,4CZ3Z@85004,COG1232@1,COG1232@2	NA|NA|NA	H	Flavin containing amine oxidoreductase
NIOIMGPL_01096	702459.BBPR_1672	5e-152	543.9	Bifidobacteriales			5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520		R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000				Bacteria	2HZ9K@201174,4CZ3Z@85004,COG1232@1,COG1232@2	NA|NA|NA	H	Flavin containing amine oxidoreductase
NIOIMGPL_01097	702459.BBPR_1673	3.3e-52	210.7	Bifidobacteriales		GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944											Bacteria	2AFXT@1,2IKPZ@201174,3161G@2,4D0UV@85004	NA|NA|NA	S	Protein of unknown function (DUF2469)
NIOIMGPL_01098	702459.BBPR_1674	1.7e-198	698.4	Bifidobacteriales			2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000				Bacteria	2I2GV@201174,4CYPW@85004,COG1670@1,COG1670@2	NA|NA|NA	J	Acetyltransferase (GNAT) domain
NIOIMGPL_01099	702459.BBPR_1675	1.4e-286	991.5	Bifidobacteriales	gatB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100		R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029				Bacteria	2GJJH@201174,4CYUY@85004,COG0064@1,COG0064@2	NA|NA|NA	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIOIMGPL_01100	398513.BBNG_01428	2.4e-289	1000.7	Bifidobacteriales	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100		R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029				Bacteria	2GJK5@201174,4CZ1X@85004,COG0154@1,COG0154@2	NA|NA|NA	F	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NIOIMGPL_01101	398513.BBNG_01427	6.2e-48	196.4	Bifidobacteriales	gatC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100		R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029				Bacteria	2IQJN@201174,4D10U@85004,COG0721@1,COG0721@2	NA|NA|NA	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIOIMGPL_01102	398513.BBNG_01426	5.3e-14	82.8	Bifidobacteriales				ko:K01990,ko:K09384		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	2GJDP@201174,4D00Y@85004,COG1131@1,COG1131@2	NA|NA|NA	V	ABC transporter
NIOIMGPL_01103	398513.BBNG_01426	2.4e-60	238.0	Bifidobacteriales				ko:K01990,ko:K09384		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	2GJDP@201174,4D00Y@85004,COG1131@1,COG1131@2	NA|NA|NA	V	ABC transporter
NIOIMGPL_01104	398513.BBNG_01424	6.9e-156	556.6	Bifidobacteriales	spoU		2.1.1.185	ko:K03218					ko00000,ko01000,ko03009				Bacteria	2GM1A@201174,4CZE8@85004,COG0566@1,COG0566@2	NA|NA|NA	J	RNA methyltransferase TrmH family
NIOIMGPL_01105	702459.BBPR_1681	7.7e-129	466.5	Bifidobacteriales	pyrE		2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000			iJN678.umpS	Bacteria	2HZDS@201174,4CZZ6@85004,COG0461@1,COG0461@2	NA|NA|NA	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NIOIMGPL_01106	702459.BBPR_1682	2.9e-214	751.1	Bifidobacteriales	rmuC			ko:K09760					ko00000				Bacteria	2GP4U@201174,4CZA5@85004,COG1322@1,COG1322@2	NA|NA|NA	S	RmuC family
NIOIMGPL_01107	398513.BBNG_01421	1.4e-42	178.7	Bifidobacteriales	csoR	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0042221,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0046688,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141		ko:K21600					ko00000,ko03000				Bacteria	2IQAC@201174,4D1A2@85004,COG1937@1,COG1937@2	NA|NA|NA	S	Metal-sensitive transcriptional repressor
NIOIMGPL_01108	398513.BBNG_01420	0.0	1647.9	Bifidobacteriales	pacS	GO:0000041,GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0016020,GO:0030001,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0071944	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016		R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5			Bacteria	2GIRF@201174,4CZ24@85004,COG2217@1,COG2217@2	NA|NA|NA	P	E1-E2 ATPase
NIOIMGPL_01109	398513.BBNG_01419	0.0	1163.3	Bifidobacteriales	ubiB			ko:K03688					ko00000				Bacteria	2GJQ6@201174,4CZ45@85004,COG0661@1,COG0661@2	NA|NA|NA	S	ABC1 family
NIOIMGPL_01110	398513.BBNG_01418	3.5e-19	100.9	Bifidobacteriales													Bacteria	2GS3M@201174,4D1FE@85004,COG3937@1,COG3937@2	NA|NA|NA	S	granule-associated protein
NIOIMGPL_01111	702459.BBPR_1687	7.5e-143	513.1	Bifidobacteriales	cobQ			ko:K07009					ko00000			iSB619.SA_RS09800	Bacteria	2GKPV@201174,4CZJ1@85004,COG3442@1,COG3442@2	NA|NA|NA	S	CobB/CobQ-like glutamine amidotransferase domain
NIOIMGPL_01112	702459.BBPR_1688	1.3e-274	951.8	Bifidobacteriales	murD		3.4.21.10,6.3.2.13,6.3.2.9	ko:K01317,ko:K01925,ko:K01928,ko:K01932	ko00300,ko00471,ko00550,ko01100,map00300,map00471,map00550,map01100		R02783,R02788	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01002,ko01011,ko04131				Bacteria	2GK18@201174,4CYTP@85004,COG0771@1,COG0771@2	NA|NA|NA	M	Domain of unknown function (DUF1727)
NIOIMGPL_01113	398513.BBNG_01415	2.2e-257	894.4	Bifidobacteriales	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112				ko00000,ko00001,ko01000,ko03032				Bacteria	2GKXQ@201174,4CYY3@85004,COG0305@1,COG0305@2	NA|NA|NA	L	Participates in initiation and elongation during chromosome replication
NIOIMGPL_01114	702459.BBPR_1690	1.2e-250	872.1	Bifidobacteriales	dinF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K03327					ko00000,ko02000	2.A.66.1			Bacteria	2GJE3@201174,4CZ75@85004,COG0534@1,COG0534@2	NA|NA|NA	V	MatE
NIOIMGPL_01115	702459.BBPR_1691	0.0	1248.0	Bifidobacteriales			2.7.7.19,2.7.7.59	ko:K00970,ko:K00990	ko02020,ko03018,map02020,map03018				ko00000,ko00001,ko01000,ko03019				Bacteria	2GMKT@201174,4D07P@85004,COG2844@1,COG2844@2	NA|NA|NA	O	Nucleotidyltransferase domain
NIOIMGPL_01116	158787.BSCA_0063	1e-54	219.2	Bifidobacteriales	glnB			ko:K04751	ko02020,map02020				ko00000,ko00001				Bacteria	2IKN1@201174,4D0VD@85004,COG0347@1,COG0347@2	NA|NA|NA	K	Nitrogen regulatory protein P-II
NIOIMGPL_01117	702459.BBPR_1693	3.4e-220	770.8	Bifidobacteriales	amt			ko:K03320					ko00000,ko02000	1.A.11			Bacteria	2GIZK@201174,4CZA0@85004,COG0004@1,COG0004@2	NA|NA|NA	U	Ammonium Transporter Family
NIOIMGPL_01118	398513.BBNG_01410	4e-202	710.7	Bifidobacteriales	ftsY	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944		ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7			Bacteria	2GJQH@201174,4CZZX@85004,COG0552@1,COG0552@2	NA|NA|NA	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NIOIMGPL_01120	398513.BBNG_01409	7.9e-116	423.3	Bifidobacteriales	icaR												Bacteria	2GMBW@201174,4CYUD@85004,COG1309@1,COG1309@2	NA|NA|NA	K	Bacterial regulatory proteins, tetR family
NIOIMGPL_01121	702459.BBPR_1697	6.6e-198	696.4	Bifidobacteriales	XK27_01805												Bacteria	2GMDK@201174,4CZIS@85004,COG0463@1,COG0463@2	NA|NA|NA	M	Glycosyltransferase like family 2
NIOIMGPL_01122	398513.BBNG_01407	0.0	1349.0	Bifidobacteriales													Bacteria	28J61@1,2HZIR@201174,2Z91S@2,4D0KC@85004	NA|NA|NA	S	Glycosyl hydrolases related to GH101 family, GH129
NIOIMGPL_01123	398513.BBNG_01406	5.4e-305	1052.7	Bifidobacteriales	pepD			ko:K08659					ko00000,ko01000,ko01002				Bacteria	2GM80@201174,4CYT0@85004,COG4690@1,COG4690@2	NA|NA|NA	E	Peptidase family C69
NIOIMGPL_01125	398513.BBNG_01404	1.1e-91	343.2	Bifidobacteriales	XK26_04485			ko:K16785	ko02010,map02010	M00582			ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35			Bacteria	2IDZ2@201174,4D0CV@85004,COG0619@1,COG0619@2	NA|NA|NA	P	Cobalt transport protein
NIOIMGPL_01126	398513.BBNG_01403	1.6e-84	318.5	Bifidobacteriales													Bacteria	2A0RN@1,2IH59@201174,30NW7@2,4D0T0@85004	NA|NA|NA		
NIOIMGPL_01127	398513.BBNG_01402	0.0	1138.6	Bifidobacteriales				ko:K06147					ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21			Bacteria	2GITR@201174,4CZWS@85004,COG1132@1,COG1132@2	NA|NA|NA	V	ABC transporter transmembrane region
NIOIMGPL_01128	398513.BBNG_01401	2.4e-301	1040.8	Bifidobacteriales				ko:K06147					ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21			Bacteria	2GITR@201174,4CYYV@85004,COG1132@1,COG1132@2	NA|NA|NA	V	ABC transporter, ATP-binding protein
NIOIMGPL_01129	398513.BBNG_01400	2.7e-91	341.3	Bifidobacteriales													Bacteria	2IQ1Z@201174,4D13P@85004,COG1846@1,COG1846@2	NA|NA|NA	K	Winged helix DNA-binding domain
NIOIMGPL_01130	398513.BBNG_01398	1.2e-302	1045.0	Bifidobacteriales													Bacteria	2IMAM@201174,4D2UC@85004,COG4932@1,COG4932@2	NA|NA|NA	M	LPXTG cell wall anchor motif
NIOIMGPL_01131	702459.BBPR_1708	3e-196	691.0	Bacteria				ko:K20276	ko02024,map02024				ko00000,ko00001				Bacteria	COG2885@1,COG2885@2	NA|NA|NA	M	chlorophyll binding
NIOIMGPL_01132	398513.BBNG_01396	4.9e-213	746.9	Bacteria				ko:K20276	ko02024,map02024				ko00000,ko00001				Bacteria	COG2885@1,COG2885@2	NA|NA|NA	M	chlorophyll binding
NIOIMGPL_01133	702459.BBPR_1709	3.6e-67	260.8	Bifidobacteriales			3.4.22.70	ko:K07284					ko00000,ko01000,ko01002,ko01011				Bacteria	2GNWT@201174,4CZMM@85004,COG3764@1,COG3764@2	NA|NA|NA	M	Sortase family
NIOIMGPL_01134	398513.BBNG_01395	1.5e-97	362.8	Bifidobacteriales			3.4.22.70	ko:K07284					ko00000,ko01000,ko01002,ko01011				Bacteria	2GNWT@201174,4CZMM@85004,COG3764@1,COG3764@2	NA|NA|NA	M	Sortase family
NIOIMGPL_01136	398513.BBNG_01394	5.1e-09	67.0	Bifidobacteriales													Bacteria	2GNWG@201174,4CZY9@85004,COG0561@1,COG0561@2	NA|NA|NA	S	Sucrose-6F-phosphate phosphohydrolase
NIOIMGPL_01137	702459.BBPR_1710	2.1e-162	578.2	Bifidobacteriales													Bacteria	2GNWG@201174,4CZY9@85004,COG0561@1,COG0561@2	NA|NA|NA	S	Sucrose-6F-phosphate phosphohydrolase
NIOIMGPL_01138	702459.BBPR_1711	2.7e-241	840.9	Bifidobacteriales													Bacteria	2IBSV@201174,4D05G@85004,COG4905@1,COG4905@2	NA|NA|NA	S	Putative ABC-transporter type IV
NIOIMGPL_01139	398513.BBNG_01392	7e-81	306.6	Bifidobacteriales													Bacteria	2C3VM@1,2IHI9@201174,32RCV@2,4D0P4@85004	NA|NA|NA		
NIOIMGPL_01140	398513.BBNG_01391	4.5e-25	120.2	Bacteria													Bacteria	COG0561@1,COG0561@2	NA|NA|NA	Q	phosphatase activity
NIOIMGPL_01141	1403946.Q615_SPAC00119G0032	1e-09	69.3	Streptococcus anginosus group			5.2.1.8	ko:K03768					ko00000,ko01000,ko03110				Bacteria	1UFDJ@1239,42DQS@671232,4HDIH@91061,COG0561@1,COG0561@2	NA|NA|NA	S	haloacid dehalogenase-like hydrolase
NIOIMGPL_01142	398513.BBNG_01390	3.4e-293	1013.4	Bifidobacteriales	bglA	GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008422,GO:0015926,GO:0016787,GO:0016798,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901657	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500		R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000		GT1	iEC55989_1330.EC55989_3188,iSSON_1240.SSON_3054,iUTI89_1310.UTI89_C1752	Bacteria	2GJAF@201174,4CYPX@85004,COG2723@1,COG2723@2	NA|NA|NA	G	Glycosyl hydrolase family 1
NIOIMGPL_01143	702459.BBPR_1715	2e-39	168.3	Bifidobacteriales	celC		2.7.1.196,2.7.1.205	ko:K02759	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2			Bacteria	2GPKA@201174,4D1CF@85004,COG1447@1,COG1447@2	NA|NA|NA	G	PTS system, Lactose/Cellobiose specific IIA subunit
NIOIMGPL_01144	398513.BBNG_01388	1.2e-48	198.7	Bifidobacteriales	celA		2.7.1.196,2.7.1.205	ko:K02760	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2			Bacteria	2ISXW@201174,4D17Z@85004,COG1440@1,COG1440@2	NA|NA|NA	G	PTS system, Lactose/Cellobiose specific IIB subunit
NIOIMGPL_01145	398513.BBNG_01387	2.1e-249	867.8	Bifidobacteriales	gmuC			ko:K02761	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.3.2			Bacteria	2ID55@201174,4D00N@85004,COG1455@1,COG1455@2	NA|NA|NA	G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIOIMGPL_01146	702459.BBPR_1718	9.3e-68	262.7	Bifidobacteriales													Bacteria	2IDRU@201174,4D0ZK@85004,COG0561@1,COG0561@2	NA|NA|NA	S	haloacid dehalogenase-like hydrolase
NIOIMGPL_01147	702459.BBPR_1720	3.6e-131	474.2	Bifidobacteriales	yydK			ko:K03489,ko:K03710					ko00000,ko03000				Bacteria	2GJZ1@201174,4CZ6A@85004,COG2188@1,COG2188@2	NA|NA|NA	K	UTRA
NIOIMGPL_01148	702459.BBPR_1721	3.8e-70	271.2	Bifidobacteriales				ko:K03612					ko00000				Bacteria	2IQ4E@201174,4D0YM@85004,COG3976@1,COG3976@2	NA|NA|NA	S	FMN_bind
NIOIMGPL_01149	398513.BBNG_01383	5.7e-149	533.5	Bifidobacteriales	macB			ko:K02003,ko:K09810	ko02010,map02010	M00255,M00258			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125			Bacteria	2GK3I@201174,4CYTA@85004,COG1136@1,COG1136@2	NA|NA|NA	V	ABC transporter, ATP-binding protein
NIOIMGPL_01150	398513.BBNG_01382	3.1e-202	711.1	Bifidobacteriales	Z012_06715			ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	2GIRW@201174,4CZEZ@85004,COG0577@1,COG0577@2	NA|NA|NA	V	FtsX-like permease family
NIOIMGPL_01151	398513.BBNG_01381	1.1e-221	775.8	Bifidobacteriales	macB_2			ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	2I91N@201174,4CZGK@85004,COG0577@1,COG0577@2	NA|NA|NA	V	ABC transporter permease
NIOIMGPL_01152	702459.BBPR_1725	3.1e-77	294.3	Bifidobacteriales													Bacteria	2GMS6@201174,4CZ19@85004,COG4393@1,COG4393@2	NA|NA|NA	S	Predicted membrane protein (DUF2318)
NIOIMGPL_01153	398513.BBNG_01380	3.1e-121	441.4	Bifidobacteriales													Bacteria	2GMS6@201174,4CZ19@85004,COG4393@1,COG4393@2	NA|NA|NA	S	Predicted membrane protein (DUF2318)
NIOIMGPL_01154	702459.BBPR_1726	5.4e-108	397.1	Bifidobacteriales	tpd			ko:K07230					ko00000,ko02000	2.A.108.2.10,2.A.108.2.4,2.A.108.2.9			Bacteria	2GNAD@201174,4CZCG@85004,COG3470@1,COG3470@2	NA|NA|NA	P	Fe2+ transport protein
NIOIMGPL_01155	702459.BBPR_1727	1.9e-306	1057.7	Bifidobacteriales	efeU_1			ko:K07243					ko00000,ko02000	2.A.108.1,2.A.108.2			Bacteria	2GJ22@201174,4D01C@85004,COG0672@1,COG0672@2	NA|NA|NA	P	Iron permease FTR1 family
NIOIMGPL_01156	398513.BBNG_01377	4.5e-22	109.8	Bifidobacteriales				ko:K08152					ko00000,ko02000	2.A.1.2			Bacteria	2HZ98@201174,4CZ0N@85004,COG2211@1,COG2211@2	NA|NA|NA	G	MFS/sugar transport protein
NIOIMGPL_01157	398513.BBNG_01376	2.9e-201	707.6	Bifidobacteriales	apbE		2.7.1.180	ko:K03734					ko00000,ko01000				Bacteria	2H8YU@201174,4CZW7@85004,COG1477@1,COG1477@2	NA|NA|NA	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NIOIMGPL_01158	398513.BBNG_01375	1.8e-37	162.2	Bifidobacteriales													Bacteria	2GN3K@201174,4D1MZ@85004,COG3177@1,COG3177@2	NA|NA|NA	S	Fic/DOC family
NIOIMGPL_01159	1690.BPSG_1178	6.3e-76	290.4	Bifidobacteriales													Bacteria	2GN3K@201174,4D1MZ@85004,COG3177@1,COG3177@2	NA|NA|NA	S	Fic/DOC family
NIOIMGPL_01160	78346.BRUM_0133	2.9e-163	581.3	Bifidobacteriales													Bacteria	2GM8F@201174,4D023@85004,COG3328@1,COG3328@2	NA|NA|NA	L	Transposase, Mutator family
NIOIMGPL_01161	398513.BBNG_01374	1.1e-290	1005.4	Bifidobacteriales	ptsI		2.7.3.9	ko:K08483	ko02060,map02060				ko00000,ko00001,ko01000,ko02000	8.A.7			Bacteria	2GIZZ@201174,4CZ52@85004,COG1080@1,COG1080@2	NA|NA|NA	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NIOIMGPL_01162	398513.BBNG_01373	1.9e-37	161.4	Bifidobacteriales	ptsH			ko:K11189					ko00000,ko02000	4.A.2.1			Bacteria	2GQX6@201174,4D19B@85004,COG1925@1,COG1925@2	NA|NA|NA	G	PTS HPr component phosphorylation site
NIOIMGPL_01163	702459.BBPR_1734	1.7e-199	701.8	Bifidobacteriales				ko:K02529					ko00000,ko03000				Bacteria	2GJRG@201174,4CZ05@85004,COG1609@1,COG1609@2	NA|NA|NA	K	helix_turn _helix lactose operon repressor
NIOIMGPL_01164	702459.BBPR_1735	1.4e-212	745.3	Bifidobacteriales	holB	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	2GJ8C@201174,4CZ4Y@85004,COG0470@1,COG0470@2	NA|NA|NA	L	DNA polymerase III
NIOIMGPL_01165	398513.BBNG_01370	1.8e-117	428.7	Bifidobacteriales	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000				Bacteria	2GNTI@201174,4CYQ8@85004,COG0125@1,COG0125@2	NA|NA|NA	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NIOIMGPL_01166	702459.BBPR_1738	0.0	1819.7	Bifidobacteriales	topA	GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097	5.99.1.2	ko:K03168					ko00000,ko01000,ko03032,ko03400				Bacteria	2GJU7@201174,4CZ85@85004,COG0550@1,COG0550@2,COG1754@1,COG1754@2	NA|NA|NA	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NIOIMGPL_01167	702459.BBPR_1739	2.5e-159	568.2	Bifidobacteriales			3.6.1.27	ko:K19302	ko00550,map00550		R05627	RC00002	ko00000,ko00001,ko01000,ko01011				Bacteria	2HIXE@201174,4CYS6@85004,COG0671@1,COG0671@2	NA|NA|NA	I	PAP2 superfamily
NIOIMGPL_01168	398513.BBNG_00868	3.8e-254	883.6	Bifidobacteriales	metE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0030312,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0040007,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0071944,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000			iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131	Bacteria	2GIXA@201174,4CYWM@85004,COG0620@1,COG0620@2	NA|NA|NA	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NIOIMGPL_01169	398513.BBNG_00806	2.6e-100	371.3	Bifidobacteriales	sixA			ko:K08296					ko00000,ko01000				Bacteria	2GJ0I@201174,4D05N@85004,COG2062@1,COG2062@2	NA|NA|NA	T	Phosphoglycerate mutase family
NIOIMGPL_01170	398513.BBNG_00805	8.2e-207	726.1	Bifidobacteriales	trmI	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.219,2.1.1.220	ko:K07442					ko00000,ko01000,ko03016				Bacteria	2GJPD@201174,4CYUG@85004,COG2519@1,COG2519@2	NA|NA|NA	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NIOIMGPL_01171	398513.BBNG_00804	8.8e-178	629.4	Bifidobacteriales													Bacteria	2GNKU@201174,4CZVA@85004,COG0657@1,COG0657@2	NA|NA|NA	I	alpha/beta hydrolase fold
NIOIMGPL_01172	158787.BSCA_1450	1.4e-23	115.2	Bifidobacteriales	rarD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944		ko:K05786					ko00000,ko02000	2.A.7.7			Bacteria	2GKCP@201174,4D0PS@85004,COG2962@1,COG2962@2	NA|NA|NA	S	EamA-like transporter family
NIOIMGPL_01173	398513.BBNG_00803	7.9e-75	287.0	Bifidobacteriales	rarD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944	3.4.17.13	ko:K01297,ko:K05786					ko00000,ko01000,ko01002,ko01011,ko02000	2.A.7.7			Bacteria	2HZT1@201174,4D1NI@85004,COG0346@1,COG0346@2,COG2962@1,COG2962@2,COG4279@1,COG4279@2	NA|NA|NA	E	Rard protein
NIOIMGPL_01174	78345.BMERY_0240	8e-28	129.0	Bifidobacteriales													Bacteria	2E37J@1,2GR14@201174,32Y79@2,4D1IM@85004	NA|NA|NA		
NIOIMGPL_01175	398513.BBNG_00801	3.6e-185	654.1	Bifidobacteriales	mcrB			ko:K07448,ko:K07452					ko00000,ko01000,ko02048				Bacteria	2IBF0@201174,4D0HD@85004,COG4127@1,COG4127@2	NA|NA|NA	L	Restriction endonuclease
NIOIMGPL_01176	1123052.AUDF01000004_gene1943	5.6e-10	71.2	Microbacteriaceae													Bacteria	2CB6S@1,2IT4E@201174,33MCV@2,4FPRK@85023	NA|NA|NA		
NIOIMGPL_01177	857290.HMPREF9156_00850	1.1e-143	516.2	Bifidobacteriales													Bacteria	2I8CR@201174,4D1MM@85004,COG0464@1,COG0464@2	NA|NA|NA	O	ATPase family associated with various cellular activities (AAA)
NIOIMGPL_01178	78344.BIGA_0787	1.6e-308	1065.1	Bifidobacteriales													Bacteria	2GNU1@201174,4D1H2@85004,COG1404@1,COG1404@2	NA|NA|NA	O	Subtilase family
NIOIMGPL_01179	216816.GS08_04870	7.3e-112	409.8	Actinobacteria													Bacteria	2GM2V@201174,COG0553@1,COG0553@2	NA|NA|NA	L	helicase
NIOIMGPL_01180	702459.BBPR_0933	4.8e-69	266.9	Bifidobacteriales	metE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0030312,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0040007,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0071944,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000			iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131	Bacteria	2GIXA@201174,4CYWM@85004,COG0620@1,COG0620@2	NA|NA|NA	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NIOIMGPL_01181	702459.BBPR_0934	9.6e-163	579.3	Bifidobacteriales	metF	GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.5.1.20	ko:K00297,ko:K21010	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,ko02025,map00670,map00720,map01100,map01120,map01200,map01523,map02025	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000			iPC815.YPO0117,iSBO_1134.SBO_3961	Bacteria	2GJTN@201174,4CZ22@85004,COG0685@1,COG0685@2	NA|NA|NA	E	Methylenetetrahydrofolate reductase
NIOIMGPL_01183	702459.BBPR_0936	0.0	2046.2	Bifidobacteriales	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89	ko:K00982					ko00000,ko01000				Bacteria	2GJ91@201174,4CYQE@85004,COG1391@1,COG1391@2	NA|NA|NA	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
NIOIMGPL_01184	702459.BBPR_0937	1.4e-181	642.1	Bifidobacteriales	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000			iZ_1308.Z5856	Bacteria	2GKNA@201174,4CYZR@85004,COG0540@1,COG0540@2	NA|NA|NA	F	Belongs to the ATCase OTCase family
NIOIMGPL_01185	702459.BBPR_0938	2e-73	281.6	Bifidobacteriales	pyrI	GO:0003674,GO:0003824,GO:0004070,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00608,ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000				Bacteria	2IFDF@201174,4D0QN@85004,COG1781@1,COG1781@2	NA|NA|NA	F	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
NIOIMGPL_01186	702459.BBPR_0939	9.8e-277	958.7	Bifidobacteriales	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000				Bacteria	2GJ0T@201174,4CZIW@85004,COG0044@1,COG0044@2	NA|NA|NA	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NIOIMGPL_01187	398513.BBNG_00875	4.1e-141	507.3	Bifidobacteriales	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.10,4.1.1.23	ko:K01591,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000			iHN637.CLJU_RS17585	Bacteria	2GKWK@201174,4CZAK@85004,COG0284@1,COG0284@2	NA|NA|NA	F	Belongs to the OMP decarboxylase family. Type 2 subfamily
NIOIMGPL_01188	398513.BBNG_00876	1.7e-156	558.5	Bifidobacteriales	pyrK		1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14	ko:K00266,ko:K00528,ko:K02823	ko00240,ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00910,map01100,map01110,map01120,map01130,map01230		R00093,R00114,R00248,R10159	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000				Bacteria	2HQ24@201174,4CZC1@85004,COG0543@1,COG0543@2	NA|NA|NA	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
NIOIMGPL_01189	398513.BBNG_00877	9.6e-180	636.0	Bifidobacteriales	pyrD		1.3.1.14	ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000				Bacteria	2GKC6@201174,4CYU2@85004,COG0167@1,COG0167@2	NA|NA|NA	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NIOIMGPL_01190	398513.BBNG_00878	2.5e-124	451.4	Bifidobacteriales	pyrE		2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000				Bacteria	2GM5A@201174,4CZHB@85004,COG0461@1,COG0461@2	NA|NA|NA	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NIOIMGPL_01191	326426.Bbr_0614	3.3e-57	227.6	Bifidobacteriales													Bacteria	2HZK3@201174,4D0RM@85004,COG0789@1,COG0789@2	NA|NA|NA	K	MerR family regulatory protein
NIOIMGPL_01192	216816.GS08_03140	6.9e-195	686.4	Bifidobacteriales			1.1.1.1,1.1.1.14	ko:K00001,ko:K00008	ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	M00014	R00623,R00754,R00875,R01896,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00085,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko00002,ko01000				Bacteria	2GISW@201174,4CZJY@85004,COG1063@1,COG1063@2	NA|NA|NA	C	Zinc-binding dehydrogenase
NIOIMGPL_01193	398513.BBNG_00881	2.6e-136	491.9	Bifidobacteriales													Bacteria	2DNFW@1,2IANA@201174,32XAQ@2,4D0ED@85004	NA|NA|NA		
NIOIMGPL_01194	326426.Bbr_0840	1.5e-17	95.1	Bifidobacteriales													Bacteria	2E529@1,2IIU2@201174,32ZVG@2,4D0Z5@85004	NA|NA|NA	K	Psort location Cytoplasmic, score
NIOIMGPL_01195	762211.BSTEL_0299	9.1e-16	89.7	Bifidobacteriales													Bacteria	2IB6I@201174,4D0BZ@85004,COG0515@1,COG0515@2	NA|NA|NA	KLT	Protein tyrosine kinase
NIOIMGPL_01196	398513.BBNG_00884	0.0	1296.6	Bifidobacteriales	uvrA3			ko:K03701	ko03420,map03420				ko00000,ko00001,ko03400				Bacteria	2GNMW@201174,4CZ5X@85004,COG0178@1,COG0178@2	NA|NA|NA	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NIOIMGPL_01197	398513.BBNG_00884	2.3e-75	288.1	Bifidobacteriales	uvrA3			ko:K03701	ko03420,map03420				ko00000,ko00001,ko03400				Bacteria	2GNMW@201174,4CZ5X@85004,COG0178@1,COG0178@2	NA|NA|NA	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NIOIMGPL_01198	702459.BBPR_0948	2.6e-227	794.7	Bifidobacteriales	vbsD												Bacteria	2GXXK@201174,4CZU6@85004,COG0534@1,COG0534@2	NA|NA|NA	V	MatE
NIOIMGPL_01199	702459.BBPR_0949	1.6e-131	475.3	Bifidobacteriales													Bacteria	2GMGQ@201174,4CZA7@85004,COG4221@1,COG4221@2	NA|NA|NA	S	Enoyl-(Acyl carrier protein) reductase
NIOIMGPL_01200	702459.BBPR_0950	2.3e-133	481.5	Bifidobacteriales	magIII			ko:K07457					ko00000				Bacteria	2ICDU@201174,4D03Q@85004,COG2231@1,COG2231@2	NA|NA|NA	L	endonuclease III
NIOIMGPL_01201	398513.BBNG_00888	1.7e-93	348.6	Bifidobacteriales	laaE												Bacteria	2I8K2@201174,4D0KJ@85004,COG1695@1,COG1695@2	NA|NA|NA	K	Transcriptional regulator PadR-like family
NIOIMGPL_01202	398513.BBNG_00889	1.8e-176	625.2	Bifidobacteriales				ko:K07088					ko00000				Bacteria	2GMWC@201174,4D0CA@85004,COG0679@1,COG0679@2	NA|NA|NA	S	Membrane transport protein
NIOIMGPL_01203	398513.BBNG_00890	8.1e-66	256.1	Bifidobacteriales			4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220		R03470	RC00938	ko00000,ko00001,ko01000				Bacteria	2IFSF@201174,4D13U@85004,COG1917@1,COG1917@2	NA|NA|NA	S	Cupin domain
NIOIMGPL_01204	398513.BBNG_00891	7e-225	786.2	Bifidobacteriales	hipA		2.7.11.1	ko:K07154					ko00000,ko01000,ko01001,ko02048				Bacteria	2IA5Z@201174,4D09R@85004,COG3550@1,COG3550@2	NA|NA|NA	S	HipA N-terminal domain
NIOIMGPL_01205	398513.BBNG_00892	3.7e-41	173.7	Bifidobacteriales													Bacteria	2IQPX@201174,4D19Q@85004,COG1396@1,COG1396@2	NA|NA|NA	K	Helix-turn-helix
NIOIMGPL_01206	702459.BBPR_0956	1.7e-47	194.9	Bacteria	tam	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0030798,GO:0032259,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0051704	2.1.1.144,2.1.1.197	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000			iECABU_c1320.ECABU_c17460,iSDY_1059.SDY_1625,ic_1306.c1942	Bacteria	COG4106@1,COG4106@2	NA|NA|NA	FG	trans-aconitate 2-methyltransferase activity
NIOIMGPL_01207	158787.BSCA_0497	3.5e-18	97.1	Bifidobacteriales													Bacteria	2A730@1,2GXVU@201174,30VYI@2,4D269@85004	NA|NA|NA		
NIOIMGPL_01208	702459.BBPR_0958	4.2e-101	374.0	Bifidobacteriales													Bacteria	2HUE7@201174,4D0RW@85004,COG3226@1,COG3226@2	NA|NA|NA	K	Bacterial regulatory proteins, tetR family
NIOIMGPL_01209	398513.BBNG_00895	4.7e-85	320.5	Bifidobacteriales													Bacteria	2I65E@201174,4D2YA@85004,COG1716@1,COG1716@2	NA|NA|NA	T	Domain of unknown function (DUF4234)
NIOIMGPL_01210	398513.BBNG_00896	1.2e-171	609.0	Bifidobacteriales	cpsY												Bacteria	2HZCU@201174,4CZT8@85004,COG0583@1,COG0583@2	NA|NA|NA	K	Bacterial regulatory helix-turn-helix protein, lysR family
NIOIMGPL_01211	398513.BBNG_00897	1.5e-123	448.7	Bifidobacteriales			3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120		R05287	RC00697	ko00000,ko00001,ko01000				Bacteria	2I8XE@201174,4D00B@85004,COG1011@1,COG1011@2	NA|NA|NA	S	Haloacid dehalogenase-like hydrolase
NIOIMGPL_01212	398513.BBNG_00898	2.5e-153	548.1	Bifidobacteriales	nnrD	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759					ko00000,ko01000				Bacteria	2GJHB@201174,4CZC5@85004,COG0062@1,COG0062@2,COG0063@1,COG0063@2	NA|NA|NA	H	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NIOIMGPL_01213	398513.BBNG_00898	2.9e-73	282.0	Bifidobacteriales	nnrD	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759					ko00000,ko01000				Bacteria	2GJHB@201174,4CZC5@85004,COG0062@1,COG0062@2,COG0063@1,COG0063@2	NA|NA|NA	H	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NIOIMGPL_01214	702459.BBPR_0963	1.2e-143	515.8	Bifidobacteriales			4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220		R03470	RC00938	ko00000,ko00001,ko01000				Bacteria	2GITB@201174,4CZBK@85004,COG0599@1,COG0599@2	NA|NA|NA	S	Carboxymuconolactone decarboxylase family
NIOIMGPL_01216	398513.BBNG_00901	3.7e-287	993.4	Bifidobacteriales	ugpA		2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000				Bacteria	2I2G3@201174,4CYTQ@85004,COG4284@1,COG4284@2	NA|NA|NA	G	UTP-glucose-1-phosphate uridylyltransferase
NIOIMGPL_01217	398513.BBNG_00902	1.1e-22	112.1	Bifidobacteriales	pafB			ko:K13573					ko00000,ko03051				Bacteria	2I8M5@201174,4CZWF@85004,COG2378@1,COG2378@2	NA|NA|NA	K	WYL domain
NIOIMGPL_01218	398513.BBNG_00004	4.5e-12	75.9	Bifidobacteriales													Bacteria	29G83@1,2GQWW@201174,3035W@2,4D1G9@85004	NA|NA|NA		
NIOIMGPL_01219	1435051.BMOU_0217	5e-13	80.1	Bifidobacteriales													Bacteria	2EK5K@1,2GSM4@201174,33DW0@2,4D1J2@85004	NA|NA|NA	S	Putative phage holin Dp-1
NIOIMGPL_01220	702459.BBPR_0970	1.7e-42	179.9	Bifidobacteriales				ko:K07273,ko:K21471					ko00000,ko01000,ko01002,ko01011				Bacteria	2I2GA@201174,4D07F@85004,COG1388@1,COG1388@2,COG3757@1,COG3757@2	NA|NA|NA	M	Glycosyl hydrolases family 25
NIOIMGPL_01221	401473.BDP_1477	2.3e-29	135.2	Bifidobacteriales				ko:K07273					ko00000				Bacteria	2I2GA@201174,4D07F@85004,COG1388@1,COG1388@2,COG3757@1,COG3757@2	NA|NA|NA	M	Glycosyl hydrolases family 25
NIOIMGPL_01223	77635.BISU_0787	1e-17	97.8	Actinobacteria													Bacteria	2ANT4@1,2HD6J@201174,31DTC@2	NA|NA|NA	S	Protein of unknown function (DUF2806)
NIOIMGPL_01225	1437608.BBIA_0616	3.5e-119	434.5	Bifidobacteriales													Bacteria	2GMZX@201174,4D0DN@85004,COG2826@1,COG2826@2	NA|NA|NA	L	Transposase and inactivated derivatives IS30 family
NIOIMGPL_01226	1437608.BBIA_0616	3.6e-67	260.8	Bifidobacteriales													Bacteria	2GMZX@201174,4D0DN@85004,COG2826@1,COG2826@2	NA|NA|NA	L	Transposase and inactivated derivatives IS30 family
NIOIMGPL_01227	1437609.BCAL_1008	3e-73	282.0	Bifidobacteriales	comF												Bacteria	2HZQY@201174,4D1AY@85004,COG1040@1,COG1040@2	NA|NA|NA	S	competence protein
NIOIMGPL_01228	1437609.BCAL_1009	3.7e-108	398.3	Bifidobacteriales	dprA			ko:K04096					ko00000				Bacteria	2IFTH@201174,4D0JN@85004,COG0758@1,COG0758@2	NA|NA|NA	LU	DNA recombination-mediator protein A
NIOIMGPL_01229	1680.BADO_0623	3e-173	614.8	Bifidobacteriales	int			ko:K14059					ko00000				Bacteria	2GMMI@201174,4D0E4@85004,COG0582@1,COG0582@2	NA|NA|NA	L	Phage integrase, N-terminal SAM-like domain
NIOIMGPL_01230	547043.BIFPSEUDO_03949	9.3e-31	139.4	Bifidobacteriales													Bacteria	2A36R@1,2HD2U@201174,30RN9@2,4D2P3@85004	NA|NA|NA		
NIOIMGPL_01231	547043.BIFPSEUDO_03948	3.2e-39	167.5	Bifidobacteriales													Bacteria	2BAM6@1,2H8UR@201174,3241Z@2,4D2EM@85004	NA|NA|NA		
NIOIMGPL_01232	547043.BIFPSEUDO_03947	5.9e-84	317.0	Bifidobacteriales													Bacteria	29W77@1,2IKED@201174,30HSE@2,4D0WN@85004	NA|NA|NA		
NIOIMGPL_01233	479437.Elen_0870	0.0	1213.4	Actinobacteria	XK27_00500												Bacteria	2HCII@201174,COG0553@1,COG0553@2,COG0827@1,COG0827@2,COG4646@1,COG4646@2	NA|NA|NA	KL	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NIOIMGPL_01235	547043.BIFPSEUDO_03947	2.8e-68	265.4	Bifidobacteriales													Bacteria	29W77@1,2IKED@201174,30HSE@2,4D0WN@85004	NA|NA|NA		
NIOIMGPL_01236	398513.BBNG_00758	7.4e-199	699.9	Bifidobacteriales	sufS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100		R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000				Bacteria	2GIVK@201174,4CZIU@85004,COG0520@1,COG0520@2	NA|NA|NA	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NIOIMGPL_01237	398513.BBNG_00757	1.4e-144	518.8	Bifidobacteriales	sufC			ko:K09013					ko00000,ko02000				Bacteria	2GKB7@201174,4CZU1@85004,COG0396@1,COG0396@2	NA|NA|NA	O	FeS assembly ATPase SufC
NIOIMGPL_01238	398513.BBNG_00756	2.6e-233	814.3	Bifidobacteriales	sufD	GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0040007,GO:0043207,GO:0044085,GO:0044237,GO:0044403,GO:0044419,GO:0050896,GO:0051186,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071840,GO:0075136		ko:K09015					ko00000			iB21_1397.B21_01640,iECBD_1354.ECBD_1964,iECB_1328.ECB_01650,iECD_1391.ECD_01650,iUMNK88_1353.UMNK88_2144	Bacteria	2GJNV@201174,4CZEE@85004,COG0719@1,COG0719@2	NA|NA|NA	O	FeS assembly protein SufD
NIOIMGPL_01239	398513.BBNG_00755	2.5e-211	741.1	Bifidobacteriales	sufB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360		ko:K07033,ko:K09014					ko00000				Bacteria	2GKCZ@201174,4CZPQ@85004,COG0719@1,COG0719@2	NA|NA|NA	O	FeS assembly protein SufB
NIOIMGPL_01240	398513.BBNG_00754	0.0	1125.9	Bifidobacteriales	pyrG	GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_1276,iECO103_1326.ECO103_3323,iHN637.CLJU_RS01075,iNJ661.Rv1699,iPC815.YPO3377	Bacteria	2GJ13@201174,4CYWE@85004,COG0504@1,COG0504@2	NA|NA|NA	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NIOIMGPL_01241	398513.BBNG_01395	6.8e-08	64.7	Bifidobacteriales			3.4.22.70	ko:K07284					ko00000,ko01000,ko01002,ko01011				Bacteria	2GNWT@201174,4CZMM@85004,COG3764@1,COG3764@2	NA|NA|NA	M	Sortase family
NIOIMGPL_01242	702459.BBPR_0809	2e-108	398.7	Bifidobacteriales													Bacteria	2IQKB@201174,4D2UE@85004,COG2197@1,COG2197@2	NA|NA|NA	K	helix_turn_helix, Lux Regulon
NIOIMGPL_01243	702459.BBPR_0808	1.4e-16	92.0	Actinobacteria													Bacteria	2EGCD@1,2GZHT@201174,33A46@2	NA|NA|NA		
NIOIMGPL_01244	398513.BBNG_00750	2.2e-78	298.1	Bifidobacteriales	aroQ	GO:0003674,GO:0003824,GO:0003855,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000			iIT341.HP1038	Bacteria	2IMBY@201174,4D0Q6@85004,COG0757@1,COG0757@2	NA|NA|NA	E	Catalyzes a trans-dehydration via an enolate intermediate
NIOIMGPL_01245	702459.BBPR_0806	2.7e-140	504.6	Bifidobacteriales	aroK	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003856,GO:0004765,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016835,GO:0016838,GO:0017076,GO:0019438,GO:0019632,GO:0019752,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71,4.2.3.4	ko:K00891,ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000				Bacteria	2GIUZ@201174,4CZ2G@85004,COG0337@1,COG0337@2,COG0703@1,COG0703@2	NA|NA|NA	H	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NIOIMGPL_01246	702459.BBPR_0805	1.6e-219	768.5	Bifidobacteriales	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_0976,iNJ661.Rv2540c	Bacteria	2GJJN@201174,4CZ43@85004,COG0082@1,COG0082@2	NA|NA|NA	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NIOIMGPL_01247	398513.BBNG_00746	2.2e-47	195.3	Bifidobacteriales			3.4.23.43	ko:K02654		M00331			ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2			Bacteria	2B59B@1,2GRM1@201174,31Y3G@2,4D110@85004	NA|NA|NA	S	Type IV leader peptidase family
NIOIMGPL_01248	398513.BBNG_00745	4.1e-188	664.1	Bifidobacteriales	mltG			ko:K07082					ko00000				Bacteria	2GKGQ@201174,4CZID@85004,COG1559@1,COG1559@2	NA|NA|NA	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NIOIMGPL_01249	398513.BBNG_00744	3e-75	287.7	Bifidobacteriales	yqgF	GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360		ko:K07447					ko00000,ko01000				Bacteria	2IQB0@201174,4D0WQ@85004,COG0816@1,COG0816@2	NA|NA|NA	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NIOIMGPL_01250	398513.BBNG_00743	1.2e-250	872.1	Bifidobacteriales	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	2GIUG@201174,4CZQN@85004,COG0013@1,COG0013@2	NA|NA|NA	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NIOIMGPL_01251	398513.BBNG_00743	8.4e-70	269.6	Bifidobacteriales	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	2GIUG@201174,4CZQN@85004,COG0013@1,COG0013@2	NA|NA|NA	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NIOIMGPL_01252	702459.BBPR_0801	3.3e-97	360.9	Bifidobacteriales	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	2GIUG@201174,4CZQN@85004,COG0013@1,COG0013@2	NA|NA|NA	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NIOIMGPL_01253	398513.BBNG_00742	1.1e-36	158.7	Bifidobacteriales													Bacteria	2B9VR@1,2IQYT@201174,3238X@2,4D16I@85004	NA|NA|NA		
NIOIMGPL_01254	398513.BBNG_00741	3.8e-64	250.8	Bifidobacteriales	WQ51_05790												Bacteria	2II1J@201174,4D0VH@85004,COG4768@1,COG4768@2	NA|NA|NA	S	Bacterial protein of unknown function (DUF948)
NIOIMGPL_01255	398513.BBNG_00740	1.9e-135	488.4	Bifidobacteriales	pgm3												Bacteria	2GK2I@201174,4CZH2@85004,COG0406@1,COG0406@2	NA|NA|NA	G	Phosphoglycerate mutase family
NIOIMGPL_01256	702459.BBPR_0797	0.0	1271.1	Bifidobacteriales	oatA	GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016020,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509											Bacteria	2GKI5@201174,4D0BY@85004,COG1835@1,COG1835@2	NA|NA|NA	I	Psort location CytoplasmicMembrane, score 9.99
NIOIMGPL_01257	398513.BBNG_00738	1.4e-96	359.0	Bifidobacteriales	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112		ko:K02986	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	2GIRX@201174,4CYSP@85004,COG0522@1,COG0522@2	NA|NA|NA	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NIOIMGPL_01258	398513.BBNG_00737	1.3e-127	462.6	Bifidobacteriales	lolD			ko:K02003		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	2IATV@201174,4CZMH@85004,COG1136@1,COG1136@2	NA|NA|NA	V	ABC transporter
NIOIMGPL_01259	702459.BBPR_0794	1.9e-212	745.0	Bifidobacteriales				ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	2H8C2@201174,4CZB5@85004,COG0577@1,COG0577@2	NA|NA|NA	V	FtsX-like permease family
NIOIMGPL_01260	702459.BBPR_0793	8.2e-64	249.6	Bifidobacteriales													Bacteria	2CBVU@1,2IKKE@201174,3324G@2,4D106@85004	NA|NA|NA	S	Domain of unknown function (DUF4418)
NIOIMGPL_01261	702459.BBPR_0792	0.0	1578.9	Bifidobacteriales	pcrA	GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430				ko00000,ko00001,ko01000,ko03400				Bacteria	2GISS@201174,4CYRJ@85004,COG0210@1,COG0210@2	NA|NA|NA	L	DNA helicase
NIOIMGPL_01262	702459.BBPR_0791	7.8e-199	699.9	Bifidobacteriales	XK27_09800												Bacteria	2GKI5@201174,4D0BY@85004,COG1835@1,COG1835@2	NA|NA|NA	I	Psort location CytoplasmicMembrane, score 9.99
NIOIMGPL_01263	398513.BBNG_00733	1.3e-111	409.1	Bifidobacteriales	yrhL												Bacteria	2GKI5@201174,4D0BY@85004,COG1835@1,COG1835@2	NA|NA|NA	I	Psort location CytoplasmicMembrane, score 9.99
NIOIMGPL_01264	398513.BBNG_00732	8.7e-107	392.9	Bifidobacteriales	xpt		2.4.2.22,2.4.2.7	ko:K00759,ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110		R00190,R01229,R02142,R04378	RC00063,RC00122	ko00000,ko00001,ko01000,ko04147				Bacteria	2GJ3S@201174,4CYSZ@85004,COG0503@1,COG0503@2	NA|NA|NA	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NIOIMGPL_01265	398513.BBNG_00731	3.1e-41	174.1	Bifidobacteriales	pbuX			ko:K03458					ko00000	2.A.40			Bacteria	2GMH6@201174,4CZ9F@85004,COG2233@1,COG2233@2	NA|NA|NA	F	Permease family
NIOIMGPL_01266	702459.BBPR_0789	6.8e-176	623.2	Bifidobacteriales	pbuX			ko:K03458					ko00000	2.A.40			Bacteria	2GMH6@201174,4CZ9F@85004,COG2233@1,COG2233@2	NA|NA|NA	F	Permease family
NIOIMGPL_01268	702459.BBPR_0788	1.4e-11	74.3	Bifidobacteriales	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931		R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002			iNJ661.Rv3436c,iSB619.SA_RS11245,iYO844.BSU01780	Bacteria	2GKH0@201174,4CZ1G@85004,COG0449@1,COG0449@2	NA|NA|NA	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NIOIMGPL_01269	1437609.BCAL_0434	2e-17	94.7	Bifidobacteriales	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931		R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002			iNJ661.Rv3436c,iSB619.SA_RS11245,iYO844.BSU01780	Bacteria	2GKH0@201174,4CZ1G@85004,COG0449@1,COG0449@2	NA|NA|NA	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NIOIMGPL_01270	702459.BBPR_0787	6.7e-90	336.7	Bifidobacteriales	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931		R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002			iNJ661.Rv3436c,iSB619.SA_RS11245,iYO844.BSU01780	Bacteria	2GKH0@201174,4CZ1G@85004,COG0449@1,COG0449@2	NA|NA|NA	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NIOIMGPL_01272	398513.BBNG_00728	3.6e-111	407.5	Bifidobacteriales	pncA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.11.1,3.5.1.19	ko:K08281,ko:K12132	ko00760,ko01100,map00760,map01100		R01268	RC00100	ko00000,ko00001,ko01000,ko01001			iE2348C_1286.E2348C_1895,iECs_1301.ECs2475,iZ_1308.Z2802	Bacteria	2IFQW@201174,4CYTT@85004,COG1335@1,COG1335@2	NA|NA|NA	Q	Isochorismatase family
NIOIMGPL_01273	398513.BBNG_00727	9e-40	169.1	Bifidobacteriales													Bacteria	2B5HY@1,2H0JI@201174,31YCN@2,4D1RA@85004	NA|NA|NA		
NIOIMGPL_01274	1123058.KB894256_gene1316	1.7e-27	128.3	Flavobacteriia			2.1.1.72	ko:K00571					ko00000,ko01000,ko02048				Bacteria	1HXKW@117743,2DB9A@1,2Z7VI@2,4NJ4U@976	NA|NA|NA	S	Adenine-specific methyltransferase EcoRI
NIOIMGPL_01275	398513.BBNG_00723	4.7e-119	434.1	Bifidobacteriales	tnp7109-21												Bacteria	2GKDY@201174,4CZUB@85004,COG2801@1,COG2801@2	NA|NA|NA	L	Integrase core domain
NIOIMGPL_01276	398513.BBNG_00722	1.9e-47	194.9	Bifidobacteriales				ko:K07483					ko00000				Bacteria	2IQ8F@201174,4D1BJ@85004,COG2963@1,COG2963@2	NA|NA|NA	L	Transposase
NIOIMGPL_01277	702459.BBPR_0780	1.3e-63	248.8	Bifidobacteriales													Bacteria	2IT30@201174,4D1A7@85004,COG1196@1,COG1196@2	NA|NA|NA	D	MobA/MobL family
NIOIMGPL_01278	398513.BBNG_00721	1.9e-65	255.4	Bifidobacteriales													Bacteria	2BPUM@1,2H7IF@201174,32IN6@2,4D2HU@85004	NA|NA|NA		
NIOIMGPL_01280	702459.BBPR_0083	1.4e-79	302.4	Bifidobacteriales													Bacteria	2GMZX@201174,4D0DN@85004,COG2826@1,COG2826@2	NA|NA|NA	L	Transposase and inactivated derivatives IS30 family
NIOIMGPL_01281	702459.BBPR_0778	4.6e-94	350.5	Bifidobacteriales													Bacteria	2GMZX@201174,4D0DN@85004,COG2826@1,COG2826@2	NA|NA|NA	L	Transposase and inactivated derivatives IS30 family
NIOIMGPL_01282	398513.BBNG_00718	2e-285	987.6	Bifidobacteriales			3.6.4.12	ko:K03655	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	2GZ30@201174,4CYSX@85004,COG2865@1,COG2865@2	NA|NA|NA	K	Putative ATP-dependent DNA helicase recG C-terminal
NIOIMGPL_01283	702459.BBPR_0776	2.7e-45	187.6	Bifidobacteriales				ko:K01992		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	2H9HW@201174,4CZ1J@85004,COG0842@1,COG0842@2	NA|NA|NA	V	ABC-2 family transporter protein
NIOIMGPL_01284	398513.BBNG_00717	6.7e-194	683.3	Bifidobacteriales				ko:K01992		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	2H9HW@201174,4CZ1J@85004,COG0842@1,COG0842@2	NA|NA|NA	V	ABC-2 family transporter protein
NIOIMGPL_01285	398513.BBNG_00716	3.8e-224	783.9	Bifidobacteriales				ko:K01992		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	2IBJP@201174,4CZD5@85004,COG0842@1,COG0842@2	NA|NA|NA	V	ABC-2 family transporter protein
NIOIMGPL_01286	702459.BBPR_0774	4.1e-127	460.7	Bifidobacteriales				ko:K01990		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	2GIY8@201174,4CYUQ@85004,COG1131@1,COG1131@2	NA|NA|NA	V	ATPases associated with a variety of cellular activities
NIOIMGPL_01287	398513.BBNG_00714	1.2e-42	178.7	Bacteria	pacL		3.6.3.8,3.6.3.9	ko:K01537,ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978				ko00000,ko00001,ko01000,ko04147	3.A.3.1,3.A.3.2			Bacteria	COG0474@1,COG0474@2	NA|NA|NA	P	ATPase, P-type transporting, HAD superfamily, subfamily IC
NIOIMGPL_01288	702459.BBPR_0772	3.2e-234	817.4	Bifidobacteriales													Bacteria	2I9G4@201174,4CZHY@85004,COG4585@1,COG4585@2	NA|NA|NA	T	Histidine kinase
NIOIMGPL_01289	702459.BBPR_0771	6.3e-120	436.8	Bifidobacteriales													Bacteria	2IBZ9@201174,4D07J@85004,COG2197@1,COG2197@2	NA|NA|NA	K	helix_turn_helix, Lux Regulon
NIOIMGPL_01290	398513.BBNG_00711	1.1e-115	422.5	Bifidobacteriales	MA20_27875			ko:K02039,ko:K07220					ko00000				Bacteria	2HNQ5@201174,4CZVQ@85004,COG1392@1,COG1392@2	NA|NA|NA	P	Protein of unknown function DUF47
NIOIMGPL_01291	702459.BBPR_0769	3.4e-189	667.5	Bifidobacteriales	pit			ko:K03306					ko00000	2.A.20			Bacteria	2GJHK@201174,4CZM7@85004,COG0306@1,COG0306@2	NA|NA|NA	P	Phosphate transporter family
NIOIMGPL_01292	398513.BBNG_00709	1.3e-81	308.9	Bifidobacteriales	xfp	GO:0003674,GO:0003824,GO:0008150,GO:0009758	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120		R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000				Bacteria	2GN27@201174,4CZT5@85004,COG3957@1,COG3957@2	NA|NA|NA	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
NIOIMGPL_01293	702459.BBPR_0768	4.1e-169	600.5	Bifidobacteriales	xfp	GO:0003674,GO:0003824,GO:0008150,GO:0009758	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120		R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000				Bacteria	2GN27@201174,4CZT5@85004,COG3957@1,COG3957@2	NA|NA|NA	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
NIOIMGPL_01294	398513.BBNG_00709	1e-109	402.9	Bifidobacteriales	xfp	GO:0003674,GO:0003824,GO:0008150,GO:0009758	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120		R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000				Bacteria	2GN27@201174,4CZT5@85004,COG3957@1,COG3957@2	NA|NA|NA	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
NIOIMGPL_01295	702459.BBPR_0767	2.3e-303	1047.3	Bifidobacteriales	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002			iJN746.PP_1032,iLJ478.TM1820,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833	Bacteria	2GM09@201174,4CZC3@85004,COG0518@1,COG0518@2,COG0519@1,COG0519@2	NA|NA|NA	F	Catalyzes the synthesis of GMP from XMP
NIOIMGPL_01296	1125712.HMPREF1316_2579	1e-24	118.6	Coriobacteriia													Bacteria	2FJM4@1,2H98Y@201174,34BAH@2,4CXYV@84998	NA|NA|NA		
NIOIMGPL_01297	585198.HMPREF0574_1620	8.2e-185	653.3	Actinobacteria													Bacteria	29ZSV@1,2H10H@201174,30MTV@2	NA|NA|NA		
NIOIMGPL_01298	742818.HMPREF9451_00722	1.1e-30	139.0	Coriobacteriia				ko:K07483					ko00000				Bacteria	2HV7B@201174,4CWFM@84998,COG2963@1,COG2963@2	NA|NA|NA	L	Transposase
NIOIMGPL_01299	502558.EGYY_15850	3e-69	268.1	Coriobacteriia				ko:K07497					ko00000				Bacteria	2GKDY@201174,4CW9S@84998,COG2801@1,COG2801@2	NA|NA|NA	L	Integrase core domain
NIOIMGPL_01301	1035193.HMPREF9073_00237	8.7e-21	105.9	Capnocytophaga													Bacteria	1ERT7@1016,1HZI1@117743,4NJZ9@976,COG1479@1,COG1479@2	NA|NA|NA	S	Psort location Cytoplasmic, score 8.96
NIOIMGPL_01302	1392487.JIAD01000001_gene544	1.1e-150	540.0	Clostridia													Bacteria	1UHG8@1239,25BDT@186801,COG1479@1,COG1479@2	NA|NA|NA	S	Protein of unknown function (DUF1524)
NIOIMGPL_01303	742722.HMPREF9463_00500	3.7e-117	427.6	Coriobacteriia													Bacteria	2EINA@1,2I8AV@201174,30Z4H@2,4CYPM@84998	NA|NA|NA	S	Protein of unknown function (DUF3800)
NIOIMGPL_01304	398513.BBNG_00007	1.1e-42	178.7	Bifidobacteriales	tnp7109-21												Bacteria	2GVZP@201174,4D1IR@85004,COG2801@1,COG2801@2	NA|NA|NA	L	Integrase core domain
NIOIMGPL_01305	398513.BBNG_00008	2.4e-43	181.8	Bifidobacteriales				ko:K02315					ko00000,ko03032				Bacteria	2H714@201174,4CZRM@85004,COG1484@1,COG1484@2	NA|NA|NA	L	IstB-like ATP binding protein
NIOIMGPL_01306	398513.BBNG_00010	1.7e-36	158.7	Bifidobacteriales		GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944		ko:K07485					ko00000				Bacteria	2GJK7@201174,4D0ME@85004,COG3464@1,COG3464@2	NA|NA|NA	L	Transposase
NIOIMGPL_01307	398513.BBNG_00011	2e-73	281.6	Bifidobacteriales													Bacteria	2IQBF@201174,4D10H@85004,COG3255@1,COG3255@2	NA|NA|NA	I	Sterol carrier protein
NIOIMGPL_01308	702459.BBPR_0092	0.0	1657.5	Bifidobacteriales	glgP	GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931		R02111		ko00000,ko00001,ko01000		GT35		Bacteria	2GIVZ@201174,4CZ3V@85004,COG0058@1,COG0058@2	NA|NA|NA	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NIOIMGPL_01309	398513.BBNG_00013	3.4e-35	153.7	Bifidobacteriales													Bacteria	2BFAJ@1,2ISGB@201174,3293I@2,4D185@85004	NA|NA|NA		
NIOIMGPL_01310	702459.BBPR_0095	7.1e-144	516.5	Bifidobacteriales	gluP		3.4.21.105	ko:K19225					ko00000,ko01000,ko01002				Bacteria	2GJYG@201174,4CZJ0@85004,COG0705@1,COG0705@2	NA|NA|NA	S	Rhomboid family
NIOIMGPL_01311	702459.BBPR_0093	6.9e-93	347.1	Bifidobacteriales				ko:K07497,ko:K09958					ko00000				Bacteria	2GKW1@201174,4CYXY@85004,COG2801@1,COG2801@2	NA|NA|NA	L	HTH-like domain
NIOIMGPL_01312	702459.BBPR_0096	6.1e-257	892.9	Bifidobacteriales				ko:K15257					ko00000,ko01000,ko03016				Bacteria	2HZAY@201174,4CZEU@85004,COG0742@1,COG0742@2	NA|NA|NA	L	ribosomal rna small subunit methyltransferase
NIOIMGPL_01313	702459.BBPR_0097	6.9e-67	260.0	Bifidobacteriales	crgA												Bacteria	2E4NY@1,2GQPW@201174,32ZHR@2,4D0ZH@85004	NA|NA|NA	D	Involved in cell division
NIOIMGPL_01314	702459.BBPR_0098	3.5e-143	514.2	Bifidobacteriales													Bacteria	2GJ9Y@201174,4CZ1A@85004,COG3879@1,COG3879@2	NA|NA|NA	S	Bacterial protein of unknown function (DUF881)
NIOIMGPL_01315	702459.BBPR_0099	1.7e-232	811.6	Bifidobacteriales	srtA		3.4.22.70	ko:K07284					ko00000,ko01000,ko01002,ko01011				Bacteria	2GKT6@201174,4CYZ5@85004,COG3764@1,COG3764@2	NA|NA|NA	M	Sortase family
NIOIMGPL_01316	398513.BBNG_00020	3.4e-120	437.6	Bifidobacteriales	trpG	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85	ko:K01664,ko:K13950	ko00790,map00790		R01716	RC00010,RC01418	ko00000,ko00001,ko01000				Bacteria	2GJUX@201174,4D09E@85004,COG0512@1,COG0512@2	NA|NA|NA	EH	para-aminobenzoate synthase glutamine amidotransferase component II
NIOIMGPL_01317	702459.BBPR_0101	0.0	1219.1	Bifidobacteriales	pknB		2.7.11.1	ko:K12132					ko00000,ko01000,ko01001				Bacteria	2GJ1J@201174,4CZFU@85004,COG0515@1,COG0515@2,COG2815@1,COG2815@2	NA|NA|NA	KLT	Protein tyrosine kinase
NIOIMGPL_01318	398513.BBNG_00022	2e-183	648.3	Bifidobacteriales													Bacteria	2GMPZ@201174,4CYUK@85004,COG0515@1,COG0515@2	NA|NA|NA	T	Protein tyrosine kinase
NIOIMGPL_01319	398513.BBNG_00023	4.8e-263	913.3	Bifidobacteriales	pbpA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464		ko:K05364	ko00550,map00550		R04519	RC00005,RC00049	ko00000,ko00001,ko01011				Bacteria	2GJUQ@201174,4CYTI@85004,COG0768@1,COG0768@2	NA|NA|NA	M	penicillin-binding protein
NIOIMGPL_01320	398513.BBNG_00024	2.8e-266	924.1	Bifidobacteriales	rodA	GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136		ko:K03588,ko:K05364,ko:K05837	ko00550,ko04112,map00550,map04112		R04519	RC00005,RC00049	ko00000,ko00001,ko01011,ko02000,ko03036	2.A.103.1			Bacteria	2GJTI@201174,4CZ67@85004,COG0772@1,COG0772@2	NA|NA|NA	D	Belongs to the SEDS family
NIOIMGPL_01321	398513.BBNG_00025	3.7e-259	900.6	Bifidobacteriales	pstP	GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	3.1.3.16	ko:K01090,ko:K20074					ko00000,ko01000,ko01009				Bacteria	2GJ3M@201174,4CZDN@85004,COG0631@1,COG0631@2	NA|NA|NA	T	Sigma factor PP2C-like phosphatases
NIOIMGPL_01322	398513.BBNG_00026	7.9e-94	349.7	Bifidobacteriales	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944											Bacteria	2GKA7@201174,4D0RN@85004,COG1716@1,COG1716@2	NA|NA|NA	T	Inner membrane component of T3SS, cytoplasmic domain
NIOIMGPL_01323	398513.BBNG_00027	1e-130	472.6	Bifidobacteriales	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363		ko:K02283					ko00000,ko02035,ko02044				Bacteria	2GNU2@201174,4CYUI@85004,COG1716@1,COG1716@2	NA|NA|NA	T	Protein of unknown function (DUF2662)
NIOIMGPL_01324	398513.BBNG_00028	0.0	1720.7	Bifidobacteriales	dpp4		3.4.14.5	ko:K01278	ko04974,map04974				ko00000,ko00001,ko01000,ko01002,ko04090,ko04147				Bacteria	2GJ6A@201174,4CZAE@85004,COG1506@1,COG1506@2	NA|NA|NA	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region
NIOIMGPL_01325	702459.BBPR_0110	0.0	1417.5	Bifidobacteriales	pip			ko:K01421					ko00000				Bacteria	2GKEM@201174,4CZ9R@85004,COG1511@1,COG1511@2	NA|NA|NA	S	YhgE Pip domain protein
NIOIMGPL_01326	398513.BBNG_00030	0.0	1146.7	Bifidobacteriales	pip			ko:K01421					ko00000				Bacteria	2GKEM@201174,4CZ2A@85004,COG1511@1,COG1511@2	NA|NA|NA	S	YhgE Pip domain protein
NIOIMGPL_01327	702459.BBPR_0112	3.9e-206	723.8	Bifidobacteriales	pldB	GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016740,GO:0016746,GO:0016747,GO:0016787,GO:0016788,GO:0044238,GO:0044464,GO:0052689,GO:0071704,GO:0071944	3.1.1.5	ko:K01048	ko00564,map00564				ko00000,ko00001,ko01000			iETEC_1333.ETEC_4102,iEcHS_1320.EcHS_A4049	Bacteria	2HZ9U@201174,4CZ5E@85004,COG2267@1,COG2267@2	NA|NA|NA	I	Serine aminopeptidase, S33
NIOIMGPL_01328	702459.BBPR_0113	2e-164	585.1	Bifidobacteriales	yicL												Bacteria	2HZCH@201174,4CZRZ@85004,COG0697@1,COG0697@2	NA|NA|NA	EG	EamA-like transporter family
NIOIMGPL_01329	398513.BBNG_00033	2.6e-103	381.7	Bifidobacteriales													Bacteria	2BFMF@1,2IGC7@201174,329FS@2,4D0RD@85004	NA|NA|NA		
NIOIMGPL_01331	398513.BBNG_00035	2.1e-196	691.4	Bifidobacteriales	msrA		1.8.4.11,1.8.4.12	ko:K07304,ko:K07305,ko:K12267					ko00000,ko01000				Bacteria	2GJ1S@201174,4CZXJ@85004,COG0225@1,COG0225@2,COG0229@1,COG0229@2	NA|NA|NA	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NIOIMGPL_01333	702459.BBPR_0119	0.0	2114.0	Bifidobacteriales													Bacteria	2GJ4Y@201174,4CZNN@85004,COG1061@1,COG1061@2,COG3886@1,COG3886@2	NA|NA|NA	KL	Domain of unknown function (DUF3427)
NIOIMGPL_01334	702459.BBPR_0120	2.5e-89	334.7	Bifidobacteriales	nudG	GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.6.1.55,3.6.1.65	ko:K03574,ko:K08320					ko00000,ko01000,ko03400			iE2348C_1286.E2348C_1887,iECP_1309.ECP_1705,iLF82_1304.LF82_1533,iNRG857_1313.NRG857_08815,iPC815.YPO2167,iSSON_1240.SSON_1397	Bacteria	2I2GY@201174,4D0UJ@85004,COG0494@1,COG0494@2	NA|NA|NA	L	NUDIX domain
NIOIMGPL_01335	398513.BBNG_00039	1.3e-40	172.6	Actinobacteria				ko:K07484,ko:K17763,ko:K21471					ko00000,ko01000,ko01002,ko01011,ko03021				Bacteria	2GWTP@201174,COG3599@1,COG3599@2	NA|NA|NA	D	DivIVA domain protein
NIOIMGPL_01336	398513.BBNG_00041	9.3e-53	212.6	Bifidobacteriales	ybjQ												Bacteria	2IQNY@201174,4D0ZM@85004,COG0393@1,COG0393@2	NA|NA|NA	S	Putative heavy-metal-binding
NIOIMGPL_01337	702459.BBPR_0123	6e-154	550.1	Bifidobacteriales													Bacteria	2GNRY@201174,4D02B@85004,COG2267@1,COG2267@2	NA|NA|NA	I	Serine aminopeptidase, S33
NIOIMGPL_01338	702459.BBPR_0124	6.3e-87	326.6	Bifidobacteriales	yjcF			ko:K02348,ko:K07000					ko00000				Bacteria	2HZKP@201174,4D0UN@85004,COG2153@1,COG2153@2	NA|NA|NA	Q	Acetyltransferase (GNAT) domain
NIOIMGPL_01340	702459.BBPR_0125	4.9e-259	899.8	Bifidobacteriales	tgt		2.4.2.29	ko:K00773			R03789,R10209	RC00063	ko00000,ko01000,ko03016				Bacteria	2GMWY@201174,4CZNX@85004,COG0343@1,COG0343@2	NA|NA|NA	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NIOIMGPL_01341	702459.BBPR_0126	1.7e-244	852.0	Bifidobacteriales	degP			ko:K08372	ko02020,map02020				ko00000,ko00001,ko01000,ko01002				Bacteria	2GJ96@201174,4CZAP@85004,COG0265@1,COG0265@2	NA|NA|NA	O	Domain present in PSD-95, Dlg, and ZO-1/2.
NIOIMGPL_01342	702459.BBPR_0127	0.0	1360.1	Bifidobacteriales	cadA												Bacteria	2GIRF@201174,4CZ4F@85004,COG2217@1,COG2217@2	NA|NA|NA	P	E1-E2 ATPase
NIOIMGPL_01343	398513.BBNG_00048	1.9e-272	944.5	Bifidobacteriales	fprA		1.18.1.2,1.19.1.1	ko:K00528			R10159		ko00000,ko01000				Bacteria	2GJ4A@201174,4CZIT@85004,COG0493@1,COG0493@2	NA|NA|NA	C	Pyridine nucleotide-disulphide oxidoreductase
NIOIMGPL_01344	702459.BBPR_0129	6.9e-170	603.2	Bifidobacteriales	htpX	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944		ko:K03799		M00743			ko00000,ko00002,ko01000,ko01002				Bacteria	2GMJF@201174,4CYVY@85004,COG0501@1,COG0501@2	NA|NA|NA	O	Belongs to the peptidase M48B family
NIOIMGPL_01349	702459.BBPR_0931	4e-126	457.6	Actinobacteria			3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036				Bacteria	2IK6V@201174,COG0791@1,COG0791@2,COG3409@1,COG3409@2	NA|NA|NA	M	NLP P60 protein
NIOIMGPL_01350	398513.BBNG_00865	6.5e-67	260.0	Bifidobacteriales													Bacteria	2DRCI@1,2GPSH@201174,33B7V@2,4D1E1@85004	NA|NA|NA	S	SPP1 phage holin
NIOIMGPL_01352	702459.BBPR_0929	3e-69	267.7	Bifidobacteriales													Bacteria	2BJPU@1,2GZ2E@201174,32E1F@2,4D1PK@85004	NA|NA|NA		
NIOIMGPL_01353	1680.BADO_1224	8.4e-26	122.9	Bacteria													Bacteria	COG0582@1,COG0582@2	NA|NA|NA	L	DNA integration
NIOIMGPL_01354	78345.BMERY_0866	2.5e-86	325.5	Bifidobacteriales													Bacteria	2CA4H@1,2GRNF@201174,3342S@2,4D1E9@85004	NA|NA|NA		
NIOIMGPL_01355	398513.BBNG_01172	2.5e-117	428.3	Bifidobacteriales													Bacteria	2B5N5@1,2GZBA@201174,31YHE@2,4D2BD@85004	NA|NA|NA		
NIOIMGPL_01356	398513.BBNG_01173	1.6e-28	131.3	Bifidobacteriales													Bacteria	29ZZ8@1,2HC0R@201174,30N10@2,4D2Q7@85004	NA|NA|NA		
NIOIMGPL_01357	398513.BBNG_01174	9.4e-16	88.6	Bifidobacteriales													Bacteria	2BBK1@1,2HA5M@201174,3253V@2,4D2NN@85004	NA|NA|NA		
NIOIMGPL_01358	547043.BIFPSEUDO_02907	1.9e-185	655.2	Bifidobacteriales													Bacteria	29W79@1,2IC42@201174,30HSG@2,4CZZM@85004	NA|NA|NA	S	Helix-turn-helix domain
NIOIMGPL_01359	398513.BBNG_01176	9.6e-42	175.6	Bifidobacteriales													Bacteria	2BPM0@1,2H71R@201174,32IE1@2,4D2AS@85004	NA|NA|NA		
NIOIMGPL_01360	547043.BIFPSEUDO_02905	2.6e-91	341.3	Bifidobacteriales													Bacteria	2BMV3@1,2IPYW@201174,32GEK@2,4D118@85004	NA|NA|NA	S	Transcription factor WhiB
NIOIMGPL_01361	398513.BBNG_01178	8.2e-117	426.4	Bifidobacteriales	parA			ko:K03496					ko00000,ko03036,ko04812				Bacteria	2ICWE@201174,4D14U@85004,COG1192@1,COG1192@2	NA|NA|NA	D	AAA domain
NIOIMGPL_01362	398513.BBNG_01183	0.0	1281.5	Bifidobacteriales	topB		5.99.1.2	ko:K03169					ko00000,ko01000,ko03032				Bacteria	2GJU7@201174,4D044@85004,COG0550@1,COG0550@2	NA|NA|NA	L	DNA topoisomerase
NIOIMGPL_01363	398513.BBNG_01182	1.1e-81	309.3	Bifidobacteriales													Bacteria	2E5BJ@1,2IMHH@201174,3303M@2,4D12T@85004	NA|NA|NA		
NIOIMGPL_01364	547043.BIFPSEUDO_03932	4.4e-60	237.3	Bifidobacteriales													Bacteria	2A1JX@1,2IKIB@201174,30PTV@2,4D0ZU@85004	NA|NA|NA		
NIOIMGPL_01365	547043.BIFPSEUDO_03931	4.6e-45	187.2	Bifidobacteriales													Bacteria	2AYDR@1,2IS31@201174,31QGN@2,4D1AE@85004	NA|NA|NA		
NIOIMGPL_01366	326426.Bbr_1154	3.8e-167	594.3	Bifidobacteriales													Bacteria	2IEM1@201174,4CZPH@85004,COG3550@1,COG3550@2	NA|NA|NA	S	HipA-like C-terminal domain
NIOIMGPL_01367	702459.BBPR_0249	3.5e-171	607.8	Bifidobacteriales	dapE		3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000				Bacteria	2GK09@201174,4CZ9K@85004,COG0624@1,COG0624@2	NA|NA|NA	E	Peptidase dimerisation domain
NIOIMGPL_01368	398513.BBNG_00163	2.2e-168	598.2	Bifidobacteriales	mdcF			ko:K07088					ko00000				Bacteria	2GNIA@201174,4CZFX@85004,COG0679@1,COG0679@2	NA|NA|NA	S	Transporter, auxin efflux carrier (AEC) family protein
NIOIMGPL_01369	398513.BBNG_00162	3.3e-256	890.6	Bifidobacteriales				ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	2GKF3@201174,4D03X@85004,COG0577@1,COG0577@2	NA|NA|NA	V	Efflux ABC transporter, permease protein
NIOIMGPL_01370	398513.BBNG_00161	1.7e-162	578.6	Bifidobacteriales				ko:K02003		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	2GM25@201174,4D0FV@85004,COG1136@1,COG1136@2	NA|NA|NA	V	ATPases associated with a variety of cellular activities
NIOIMGPL_01371	398513.BBNG_00160	2.6e-56	224.6	Bifidobacteriales													Bacteria	2B66H@1,2H1MR@201174,31Z3P@2,4D2PR@85004	NA|NA|NA		
NIOIMGPL_01372	702459.BBPR_0244	2.7e-64	251.1	Bifidobacteriales													Bacteria	2B304@1,2GVW8@201174,31VMB@2,4D2FV@85004	NA|NA|NA		
NIOIMGPL_01373	702459.BBPR_0243	1.2e-277	961.8	Bifidobacteriales	maf	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047429	1.1.1.25,2.1.1.190,3.6.1.55,3.6.1.67	ko:K00014,ko:K03215,ko:K03574,ko:K06287,ko:K08310	ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00400,map00790,map01100,map01110,map01130,map01230	M00022,M00126	R02413,R04638	RC00002,RC00206	ko00000,ko00001,ko00002,ko01000,ko03009,ko03400				Bacteria	2GNI0@201174,4CZXF@85004,COG0424@1,COG0424@2,COG1051@1,COG1051@2	NA|NA|NA	DF	Maf-like protein
NIOIMGPL_01374	398513.BBNG_00157	5.4e-189	666.8	Bifidobacteriales	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000			iECSE_1348.ECSE_0003,iJN678.thrB,iLJ478.TM0545,iSB619.SA_RS06620	Bacteria	2GKIW@201174,4CZN0@85004,COG0083@1,COG0083@2	NA|NA|NA	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NIOIMGPL_01375	702459.BBPR_0241	5.7e-239	833.2	Bifidobacteriales	hom	GO:0003674,GO:0003824,GO:0004412,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000			iNJ661.Rv1294,iSB619.SA_RS06610	Bacteria	2GIX9@201174,4CZVD@85004,COG0460@1,COG0460@2	NA|NA|NA	E	Homoserine dehydrogenase
NIOIMGPL_01376	398513.BBNG_00155	8.4e-290	1002.3	Bifidobacteriales	nagE		2.7.1.193,2.7.1.199	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	M00267,M00809	R02738,R05199	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.13,4.A.1.1.14,4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7,4.A.1.1.9		iSB619.SA_RS08720	Bacteria	2GKPM@201174,4D069@85004,COG1263@1,COG1263@2,COG1264@1,COG1264@2	NA|NA|NA	G	phosphotransferase system, EIIB
NIOIMGPL_01377	702459.BBPR_0239	1.9e-81	308.5	Bifidobacteriales			2.7.1.208	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	M00265,M00266,M00268,M00270,M00272,M00303,M00806	R02738,R02780,R04111,R04394,R05132,R08559	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1,4.A.1.1.11,4.A.1.1.12			Bacteria	2INQB@201174,4D11R@85004,COG2190@1,COG2190@2	NA|NA|NA	G	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NIOIMGPL_01378	702459.BBPR_0238	5.7e-305	1052.7	Bifidobacteriales	lysA		4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000				Bacteria	2GKAI@201174,4CYRG@85004,COG0019@1,COG0019@2	NA|NA|NA	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NIOIMGPL_01379	702459.BBPR_0236	0.0	1181.8	Bifidobacteriales	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029			iAF987.Gmet_1434	Bacteria	2GKQ3@201174,4CZ9J@85004,COG0018@1,COG0018@2	NA|NA|NA	J	Arginyl-tRNA synthetase
NIOIMGPL_01380	702459.BBPR_0235	6.8e-181	639.8	Bifidobacteriales			3.1.4.46	ko:K01126	ko00564,map00564		R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000				Bacteria	2HZMC@201174,4D0XD@85004,COG0584@1,COG0584@2	NA|NA|NA	C	Glycerophosphoryl diester phosphodiesterase family
NIOIMGPL_01381	398513.BBNG_00150	5.2e-63	246.9	Bifidobacteriales	psp1		3.5.99.10	ko:K09022			R11098,R11099	RC03275,RC03354	ko00000,ko01000				Bacteria	2IFCR@201174,4D0QD@85004,COG0251@1,COG0251@2	NA|NA|NA	J	Endoribonuclease L-PSP
NIOIMGPL_01382	702459.BBPR_0233	2.2e-156	558.1	Bifidobacteriales	gnpA	GO:0003674,GO:0003824,GO:0004645,GO:0005975,GO:0008150,GO:0008152,GO:0016740,GO:0016757,GO:0016758,GO:0044238,GO:0050500,GO:0071704	2.4.1.211	ko:K15533					ko00000,ko01000				Bacteria	2GN2A@201174,4CYZB@85004,COG5426@1,COG5426@2	NA|NA|NA	S	Lacto-N-biose phosphorylase C-terminal domain
NIOIMGPL_01383	398513.BBNG_00149	7.2e-28	129.4	Bifidobacteriales	gnpA	GO:0003674,GO:0003824,GO:0004645,GO:0005975,GO:0008150,GO:0008152,GO:0016740,GO:0016757,GO:0016758,GO:0044238,GO:0050500,GO:0071704	2.4.1.211	ko:K15533					ko00000,ko01000				Bacteria	2GN2A@201174,4CYZB@85004,COG5426@1,COG5426@2	NA|NA|NA	S	Lacto-N-biose phosphorylase C-terminal domain
NIOIMGPL_01384	702459.BBPR_0233	1.1e-89	335.9	Bifidobacteriales	gnpA	GO:0003674,GO:0003824,GO:0004645,GO:0005975,GO:0008150,GO:0008152,GO:0016740,GO:0016757,GO:0016758,GO:0044238,GO:0050500,GO:0071704	2.4.1.211	ko:K15533					ko00000,ko01000				Bacteria	2GN2A@201174,4CYZB@85004,COG5426@1,COG5426@2	NA|NA|NA	S	Lacto-N-biose phosphorylase C-terminal domain
NIOIMGPL_01386	702459.BBPR_0231	5.6e-152	543.5	Bifidobacteriales													Bacteria	2GJGM@201174,4CZXI@85004,COG1028@1,COG1028@2	NA|NA|NA	IQ	KR domain
NIOIMGPL_01387	702459.BBPR_0230	1.4e-37	161.8	Bifidobacteriales			4.2.1.68	ko:K18334	ko00051,ko01120,map00051,map01120		R03688	RC00543	ko00000,ko00001,ko01000				Bacteria	2GKSK@201174,4D0EI@85004,COG4948@1,COG4948@2	NA|NA|NA	M	Enolase C-terminal domain-like
NIOIMGPL_01388	702459.BBPR_0229	1.6e-17	94.4	Bacteria			4.2.1.68	ko:K18334	ko00051,ko01120,map00051,map01120		R03688	RC00543	ko00000,ko00001,ko01000				Bacteria	COG4948@1,COG4948@2	NA|NA|NA	M	carboxylic acid catabolic process
NIOIMGPL_01389	398513.BBNG_00145	1.4e-184	652.1	Bifidobacteriales				ko:K02529,ko:K17640					ko00000,ko03000				Bacteria	2GJRG@201174,4CZI0@85004,COG1609@1,COG1609@2	NA|NA|NA	K	Bacterial regulatory proteins, lacI family
NIOIMGPL_01391	398513.BBNG_00144	2.4e-118	431.4	Bifidobacteriales	cyaA	GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0050355	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000				Bacteria	2GWD8@201174,4CZKD@85004,COG2954@1,COG2954@2	NA|NA|NA	S	CYTH
NIOIMGPL_01392	398513.BBNG_00143	5.5e-162	577.0	Bifidobacteriales	trxA2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944		ko:K03671,ko:K05838	ko04621,ko05418,map04621,map05418				ko00000,ko00001,ko03110				Bacteria	2GJ7B@201174,4CZHU@85004,COG3118@1,COG3118@2	NA|NA|NA	O	Tetratricopeptide repeat
NIOIMGPL_01393	398513.BBNG_00142	7.9e-180	636.3	Bifidobacteriales													Bacteria	28PR0@1,2GNNZ@201174,2ZCCY@2,4CYX7@85004	NA|NA|NA		
NIOIMGPL_01394	398513.BBNG_00141	2.2e-188	664.8	Bifidobacteriales													Bacteria	2DMQ0@1,2IA0N@201174,32SYI@2,4CYQ0@85004	NA|NA|NA		
NIOIMGPL_01395	702459.BBPR_0223	9.8e-167	592.8	Bifidobacteriales	fkbB		5.2.1.8	ko:K01802					ko00000,ko01000				Bacteria	2GJK2@201174,4CZEF@85004,COG0545@1,COG0545@2	NA|NA|NA	M	FKBP-type peptidyl-prolyl cis-trans isomerase
NIOIMGPL_01396	398513.BBNG_00139	6.1e-123	446.8	Bifidobacteriales	rplA	GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113		ko:K02863	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	2GM51@201174,4CZFR@85004,COG0081@1,COG0081@2	NA|NA|NA	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NIOIMGPL_01397	398513.BBNG_00138	2.3e-72	278.1	Bifidobacteriales	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02867	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	2IFCK@201174,4D0PA@85004,COG0080@1,COG0080@2	NA|NA|NA	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NIOIMGPL_01398	398513.BBNG_00136	2.5e-132	478.4	Bifidobacteriales													Bacteria	29W7A@1,2IQ2G@201174,30HSH@2,4D15I@85004	NA|NA|NA		
NIOIMGPL_01399	398513.BBNG_00135	2.1e-131	474.9	Bifidobacteriales													Bacteria	2HZJX@201174,4D0QJ@85004,COG1309@1,COG1309@2	NA|NA|NA	K	Bacterial regulatory proteins, tetR family
NIOIMGPL_01400	702459.BBPR_0218	1.6e-223	781.9	Bifidobacteriales													Bacteria	2HZ9S@201174,4CZ4Z@85004,COG2271@1,COG2271@2	NA|NA|NA	G	Transmembrane secretion effector
NIOIMGPL_01401	398513.BBNG_00133	9.8e-255	885.6	Bifidobacteriales	murA		2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100		R00660	RC00350	ko00000,ko00001,ko01000,ko01011				Bacteria	2GJPW@201174,4CZN7@85004,COG0766@1,COG0766@2	NA|NA|NA	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NIOIMGPL_01402	398513.BBNG_00131	1.4e-220	771.9	Bifidobacteriales	pyrD		1.3.1.14	ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000				Bacteria	2GJMN@201174,4CZKM@85004,COG0167@1,COG0167@2	NA|NA|NA	F	Dihydroorotate dehydrogenase
NIOIMGPL_01403	398513.BBNG_00130	5.1e-180	637.1	Bifidobacteriales				ko:K07052					ko00000				Bacteria	2I3DW@201174,4CZJZ@85004,COG1266@1,COG1266@2	NA|NA|NA	S	CAAX protease self-immunity
NIOIMGPL_01405	702459.BBPR_0212	0.0	2592.4	Bifidobacteriales	snf		2.7.11.1	ko:K08282					ko00000,ko01000				Bacteria	2GISC@201174,4CZSD@85004,COG0553@1,COG0553@2	NA|NA|NA	KL	Psort location Cytoplasmic, score 8.87
NIOIMGPL_01406	398513.BBNG_00125	3.8e-133	480.7	Bifidobacteriales	leuD	GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000			iNJ661.Rv2987c	Bacteria	2GJ8Z@201174,4CZ2F@85004,COG0066@1,COG0066@2	NA|NA|NA	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NIOIMGPL_01407	398513.BBNG_00124	2.2e-273	947.6	Bifidobacteriales	leuC	GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000			iEcE24377_1341.EcE24377A_0075,iPC815.YPO0531	Bacteria	2GKT7@201174,4CYUC@85004,COG0065@1,COG0065@2	NA|NA|NA	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NIOIMGPL_01408	398513.BBNG_00123	2.2e-138	498.4	Bifidobacteriales	ltbR												Bacteria	2GKB0@201174,4CZ9D@85004,COG1414@1,COG1414@2	NA|NA|NA	K	Transcriptional regulator, IclR family, C-terminal domain protein
NIOIMGPL_01409	398513.BBNG_00122	5.8e-252	876.3	Bifidobacteriales													Bacteria	2HRDZ@201174,4CYQR@85004,COG1409@1,COG1409@2	NA|NA|NA	S	Calcineurin-like phosphoesterase
NIOIMGPL_01412	702459.BBPR_0207	1.6e-64	251.9	Bifidobacteriales				ko:K07133					ko00000				Bacteria	2GK1Q@201174,4CZNQ@85004,COG1373@1,COG1373@2	NA|NA|NA	S	Domain of unknown function (DUF4143)
NIOIMGPL_01413	398513.BBNG_00121	8.4e-88	330.1	Bifidobacteriales				ko:K07133					ko00000				Bacteria	2GK1Q@201174,4CZNQ@85004,COG1373@1,COG1373@2	NA|NA|NA	S	Domain of unknown function (DUF4143)
NIOIMGPL_01414	398513.BBNG_00120	2.9e-276	957.2	Bifidobacteriales	gltX	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016			iNJ661.Rv2992c	Bacteria	2GJJS@201174,4CZHK@85004,COG0008@1,COG0008@2	NA|NA|NA	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NIOIMGPL_01416	398513.BBNG_00118	1.2e-120	439.1	Bifidobacteriales													Bacteria	2GJNG@201174,4CYZV@85004,COG0637@1,COG0637@2	NA|NA|NA	S	HAD hydrolase, family IA, variant 3
NIOIMGPL_01417	398513.BBNG_00117	8.6e-201	706.1	Bifidobacteriales				ko:K02051		M00188			ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17			Bacteria	2HZ9T@201174,4CZ56@85004,COG0715@1,COG0715@2	NA|NA|NA	P	NMT1/THI5 like
NIOIMGPL_01418	702459.BBPR_0202	5.8e-138	496.9	Bifidobacteriales	ytlD1		2.7.1.50	ko:K00878,ko:K15599	ko00730,ko01100,ko02010,map00730,map01100,map02010	M00127,M00442	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.17.3,3.A.1.17.6			Bacteria	2GKKZ@201174,4CZ9Q@85004,COG0600@1,COG0600@2	NA|NA|NA	P	Binding-protein-dependent transport system inner membrane component
NIOIMGPL_01419	702459.BBPR_0201	1.2e-142	512.7	Bifidobacteriales													Bacteria	2BR5C@1,2I8T9@201174,32K3E@2,4CZ8U@85004	NA|NA|NA		
NIOIMGPL_01420	702459.BBPR_0200	1.1e-124	452.6	Bifidobacteriales			3.1.3.3,3.1.3.73	ko:K02226,ko:K22305	ko00260,ko00680,ko00860,ko01100,ko01120,ko01130,map00260,map00680,map00860,map01100,map01120,map01130	M00122	R00582,R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	2GMXF@201174,4CZ0Z@85004,COG0406@1,COG0406@2	NA|NA|NA	G	Phosphoglycerate mutase family
NIOIMGPL_01421	398513.BBNG_00113	1.1e-262	912.1	Bifidobacteriales													Bacteria	2GKMQ@201174,4CZ6D@85004,COG0477@1,COG2814@2	NA|NA|NA	EGP	Major facilitator Superfamily
NIOIMGPL_01422	702459.BBPR_0198	2.6e-97	361.3	Bifidobacteriales													Bacteria	2HZBR@201174,4CZM6@85004,COG2246@1,COG2246@2	NA|NA|NA	S	GtrA-like protein
NIOIMGPL_01423	398513.BBNG_00111	1.1e-61	242.3	Bifidobacteriales													Bacteria	2II0W@201174,4D0VC@85004,COG1942@1,COG1942@2	NA|NA|NA	S	Macrophage migration inhibitory factor (MIF)
NIOIMGPL_01424	702459.BBPR_0196	5.5e-286	989.6	Bifidobacteriales	fhs	GO:0000096,GO:0000097,GO:0000105,GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006520,GO:0006547,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009108,GO:0009110,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0052803,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.5,3.5.4.9,6.3.4.3	ko:K00288,ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00141,M00377	R00943,R01220,R01655	RC00026,RC00111,RC00202,RC00578	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	2GT0X@201174,4CZ7P@85004,COG2759@1,COG2759@2	NA|NA|NA	F	Formate-tetrahydrofolate ligase
NIOIMGPL_01425	702459.BBPR_0195	0.0	1095.1	Bifidobacteriales	pepD			ko:K08659					ko00000,ko01000,ko01002				Bacteria	2GM80@201174,4CZI5@85004,COG4690@1,COG4690@2	NA|NA|NA	E	Peptidase family C69
NIOIMGPL_01426	702459.BBPR_0194	1.3e-107	395.6	Bifidobacteriales				ko:K06910					ko00000				Bacteria	2I5K1@201174,4CZSW@85004,COG1881@1,COG1881@2	NA|NA|NA	S	Phosphatidylethanolamine-binding protein
NIOIMGPL_01427	702459.BBPR_0193	0.0	2548.1	Bifidobacteriales			3.2.1.51	ko:K15923	ko00511,map00511				ko00000,ko00001,ko01000		GH95		Bacteria	2GJXJ@201174,4CZZK@85004,COG1554@1,COG1554@2,COG3210@1,COG3210@2	NA|NA|NA	G	Glycosyl hydrolase family 65, N-terminal domain
NIOIMGPL_01428	702459.BBPR_0193	1.9e-196	691.8	Bifidobacteriales			3.2.1.51	ko:K15923	ko00511,map00511				ko00000,ko00001,ko01000		GH95		Bacteria	2GJXJ@201174,4CZZK@85004,COG1554@1,COG1554@2,COG3210@1,COG3210@2	NA|NA|NA	G	Glycosyl hydrolase family 65, N-terminal domain
NIOIMGPL_01429	702459.BBPR_0192	0.0	1260.0	Bifidobacteriales	lmrA2			ko:K06147					ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21			Bacteria	2GITR@201174,4CZTU@85004,COG1132@1,COG1132@2	NA|NA|NA	V	ABC transporter transmembrane region
NIOIMGPL_01430	702459.BBPR_0191	0.0	1149.4	Bifidobacteriales	lmrA1			ko:K02021,ko:K06147					ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21			Bacteria	2GITR@201174,4CYYV@85004,COG1132@1,COG1132@2	NA|NA|NA	V	ABC transporter, ATP-binding protein
NIOIMGPL_01431	398513.BBNG_00104	5.9e-94	350.1	Bifidobacteriales	ydgJ												Bacteria	2IMKE@201174,4CYZZ@85004,COG1846@1,COG1846@2	NA|NA|NA	K	helix_turn_helix multiple antibiotic resistance protein
NIOIMGPL_01432	398513.BBNG_00103	6.4e-42	176.4	Bifidobacteriales													Bacteria	2B12Y@1,2GSE7@201174,31TGH@2,4D1GD@85004	NA|NA|NA	S	Protein of unknown function (DUF1778)
NIOIMGPL_01433	702459.BBPR_0188	3.7e-190	670.6	Bifidobacteriales			1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120		R01708	RC00116	ko00000,ko00001,ko01000				Bacteria	2GJ6R@201174,4CZ9P@85004,COG0667@1,COG0667@2	NA|NA|NA	C	Aldo/keto reductase family
NIOIMGPL_01434	216816.GS08_10135	9.1e-36	157.1	Bifidobacteriales													Bacteria	2HPZN@201174,4D0F9@85004,COG5520@1,COG5520@2	NA|NA|NA	M	F5/8 type C domain
NIOIMGPL_01435	1437608.BBIA_1072	8.9e-53	213.0	Bifidobacteriales													Bacteria	29SSD@1,2IJ1J@201174,30DYB@2,4D0SG@85004	NA|NA|NA		
NIOIMGPL_01437	326426.Bbr_0209	1.3e-111	409.1	Bifidobacteriales	pptA		6.3.2.14	ko:K02362	ko01053,ko01110,ko01130,map01053,map01110,map01130		R07644	RC00162,RC03046	ko00000,ko00001,ko01000				Bacteria	2IIA2@201174,4D0IW@85004,COG2977@1,COG2977@2	NA|NA|NA	Q	4'-phosphopantetheinyl transferase superfamily
NIOIMGPL_01438	398513.BBNG_00096	3e-113	414.5	Bifidobacteriales													Bacteria	2IRA8@201174,4D0DY@85004,COG1309@1,COG1309@2	NA|NA|NA	K	WHG domain
NIOIMGPL_01439	326426.Bbr_0204	2e-32	145.2	Bifidobacteriales			1.3.3.6,2.3.1.39	ko:K00232,ko:K00645	ko00061,ko00071,ko00333,ko00592,ko01040,ko01100,ko01110,ko01130,ko01212,ko03320,ko04024,ko04146,map00061,map00071,map00333,map00592,map01040,map01100,map01110,map01130,map01212,map03320,map04024,map04146	M00082,M00087,M00113	R01175,R01279,R01626,R03777,R03857,R03990,R04751,R04754,R07888,R07892,R07896,R07934,R07950,R11671	RC00004,RC00039,RC00052,RC00076,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	2HZQU@201174,4D1A9@85004,COG0331@1,COG0331@2,COG1028@1,COG1028@2,COG3321@1,COG3321@2	NA|NA|NA	IQ	[acyl-carrier-protein] S-malonyltransferase activity
NIOIMGPL_01440	398513.BBNG_00093	8.5e-266	922.5	Bifidobacteriales													Bacteria	2GIUM@201174,4D0BX@85004,COG0477@1,COG0477@2	NA|NA|NA	EGP	Major Facilitator Superfamily
NIOIMGPL_01441	702459.BBPR_0166	3.5e-302	1043.5	Bifidobacteriales			3.6.4.12	ko:K03655	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	2I3IG@201174,4CZRW@85004,COG2865@1,COG2865@2	NA|NA|NA	K	Putative ATP-dependent DNA helicase recG C-terminal
NIOIMGPL_01442	702459.BBPR_0165	6.7e-150	536.6	Bifidobacteriales				ko:K07454					ko00000				Bacteria	2HZE0@201174,4CZZR@85004,COG3440@1,COG3440@2	NA|NA|NA	L	HNH endonuclease
NIOIMGPL_01443	702459.BBPR_0164	0.0	1487.2	Bifidobacteriales	bga1		3.2.1.23	ko:K12308	ko00052,map00052		R01105	RC00452	ko00000,ko00001,ko01000				Bacteria	2GMDT@201174,4CZ38@85004,COG1874@1,COG1874@2	NA|NA|NA	G	Psort location Cytoplasmic, score 8.87
NIOIMGPL_01444	398513.BBNG_00086	0.0	1528.1	Bifidobacteriales	yvnB		3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025		R00191	RC00296	ko00000,ko00001,ko01000				Bacteria	2GNU9@201174,4CZXA@85004,COG1409@1,COG1409@2	NA|NA|NA	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NIOIMGPL_01445	1437600.JDUI01000001_gene496	1.5e-23	115.2	Bifidobacteriales		GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944		ko:K07485					ko00000				Bacteria	2GJK7@201174,4D0ME@85004,COG3464@1,COG3464@2	NA|NA|NA	L	Transposase
NIOIMGPL_01446	702459.BBPR_0161	4.9e-86	324.3	Bifidobacteriales		GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944		ko:K07485					ko00000				Bacteria	2GJK7@201174,4D0ME@85004,COG3464@1,COG3464@2	NA|NA|NA	L	Transposase
NIOIMGPL_01447	1435051.BMOU_0530	2.8e-72	278.5	Bifidobacteriales													Bacteria	2I8ZN@201174,2Z7VT@2,4CZPC@85004,arCOG06613@1	NA|NA|NA	S	AIPR protein
NIOIMGPL_01448	398513.BBNG_00083	2.1e-41	174.5	Bifidobacteriales	XAC3035			ko:K06191					ko00000				Bacteria	2HZQB@201174,4D18H@85004,COG0695@1,COG0695@2	NA|NA|NA	O	Glutaredoxin
NIOIMGPL_01449	702459.BBPR_0159	8.9e-149	533.1	Bifidobacteriales				ko:K07058					ko00000				Bacteria	2GN79@201174,4CZM4@85004,COG1295@1,COG1295@2	NA|NA|NA	S	Virulence factor BrkB
NIOIMGPL_01450	398513.BBNG_00081	1.9e-98	365.2	Bifidobacteriales	bcp	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0032843,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K03564					ko00000,ko01000			iPC815.YPO3064	Bacteria	2IHZ6@201174,4D0PN@85004,COG1225@1,COG1225@2	NA|NA|NA	O	Redoxin
NIOIMGPL_01451	702459.BBPR_0157	2.9e-38	164.1	Bifidobacteriales				ko:K01996	ko02010,ko02024,map02010,map02024	M00237			ko00000,ko00001,ko00002,ko02000	3.A.1.4			Bacteria	2GKSQ@201174,4D0EB@85004,COG0410@1,COG0410@2	NA|NA|NA	E	ABC transporter
NIOIMGPL_01452	398513.BBNG_00079	5.1e-116	423.7	Bifidobacteriales	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100		R00966	RC00063	ko00000,ko00001,ko01000				Bacteria	2GPJE@201174,4CYVS@85004,COG0035@1,COG0035@2	NA|NA|NA	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NIOIMGPL_01453	398513.BBNG_00078	8.6e-84	316.2	Bifidobacteriales	rlmH		2.1.1.177	ko:K00783					ko00000,ko01000,ko03009				Bacteria	2IJE0@201174,4D0P5@85004,COG1576@1,COG1576@2	NA|NA|NA	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NIOIMGPL_01454	398513.BBNG_00077	0.0	1539.6	Bifidobacteriales				ko:K02004,ko:K06994		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	2I2FK@201174,4CZJR@85004,COG0577@1,COG0577@2,COG1511@1,COG1511@2	NA|NA|NA	V	FtsX-like permease family
NIOIMGPL_01455	398513.BBNG_00076	7.5e-129	466.5	Bifidobacteriales				ko:K02003,ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	2GJQV@201174,4CYT2@85004,COG1136@1,COG1136@2	NA|NA|NA	V	ABC transporter
NIOIMGPL_01456	398513.BBNG_00075	7e-101	373.2	Bifidobacteriales													Bacteria	2HZBI@201174,4CZJ8@85004,COG1309@1,COG1309@2	NA|NA|NA	K	Transcriptional regulator C-terminal region
NIOIMGPL_01457	398513.BBNG_00073	1.3e-274	951.8	Bifidobacteriales	aroP	GO:0003333,GO:0003674,GO:0005215,GO:0005302,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008104,GO:0008150,GO:0008320,GO:0008324,GO:0008509,GO:0008514,GO:0008565,GO:0009977,GO:0015031,GO:0015075,GO:0015171,GO:0015173,GO:0015179,GO:0015192,GO:0015196,GO:0015238,GO:0015291,GO:0015318,GO:0015399,GO:0015405,GO:0015450,GO:0015711,GO:0015801,GO:0015807,GO:0015823,GO:0015827,GO:0015828,GO:0015833,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0033036,GO:0034220,GO:0042221,GO:0042493,GO:0042886,GO:0042887,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1904680,GO:1905039		ko:K03293,ko:K11732,ko:K11734					ko00000,ko02000	2.A.3.1,2.A.3.1.1,2.A.3.1.3		iAPECO1_1312.APECO1_1472,iECW_1372.ECW_m0628,iEcE24377_1341.EcE24377A_0114,iEcolC_1368.EcolC_3070,iJN746.PP_4495,iUTI89_1310.UTI89_C0576,iWFL_1372.ECW_m0628	Bacteria	2GJ0X@201174,4CZ4X@85004,COG1113@1,COG1113@2	NA|NA|NA	E	aromatic amino acid transport protein AroP K03293
NIOIMGPL_01458	398513.BBNG_00071	0.0	2489.9	Bifidobacteriales	lacZ		3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100		R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000				Bacteria	2GMAT@201174,4CYYS@85004,COG3250@1,COG3250@2	NA|NA|NA	G	Psort location Cytoplasmic, score 8.87
NIOIMGPL_01459	702459.BBPR_0149	2.6e-183	647.9	Bifidobacteriales	gmk		1.1.1.23,2.7.4.8	ko:K00013,ko:K00942	ko00230,ko00340,ko01100,ko01110,ko01230,map00230,map00340,map01100,map01110,map01230	M00026,M00050	R00332,R01158,R01163,R02090,R03012	RC00002,RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000				Bacteria	2GN40@201174,4CZJT@85004,COG2852@1,COG2852@2	NA|NA|NA	S	Protein of unknown function (DUF559)
NIOIMGPL_01460	398513.BBNG_00069	4e-83	313.9	Bifidobacteriales	ilvC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000				Bacteria	2GKXA@201174,4CZBR@85004,COG0059@1,COG0059@2	NA|NA|NA	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
# 1345 queries scanned
# Total time (seconds): 3.51332116127
# Rate: 382.83 q/s