GCA_002076025.1 - 5 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

NAQJ01000017.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 9.1	RiPP-like	156,239	166,631

NAQJ01000003.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 20.1	lanthipeptide-class-v	7,212	49,101	N-octanoyl-Met-Phe-H	NRP	22%
Region 20.2	NRPS-like	172,182	215,193	nosiheptide	RiPP:Thiopeptide	7%

NAQJ01000006.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 23.1	RiPP-like,lanthipeptide-class-ii	3,914	36,613
Region 23.2	lanthipeptide-class-iii,RRE-containing	70,633	100,289

Region	Type	From	To	Most similar known cluster	Similarity
Region 9.1	RiPP-like	156,239	166,631
Region 20.1	lanthipeptide-class-v	7,212	49,101	N-octanoyl-Met-Phe-H	NRP	22%
Region 20.2	NRPS-like	172,182	215,193	nosiheptide	RiPP:Thiopeptide	7%
Region 23.1	RiPP-like,lanthipeptide-class-ii	3,914	36,613
Region 23.2	lanthipeptide-class-iii,RRE-containing	70,633	100,289

Compact view

NAQJ01000017.1 - Region 1 - RiPP-like

Download region GenBank file

Download region SVG

Location: 156,239 - 166,631 nt. (total: 10,393 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

KnownClusterBlast

Similar known gene clusters

No matches found.

NAQJ01000003.1 - Region 1 - lanthipeptide-class-v

Download region GenBank file

Download region SVG

Location: 7,212 - 49,101 nt. (total: 41,890 nt) Show pHMM detection rules used

lanthipeptide-class-v: (APH and HopA1)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Lanthipeptides

KnownClusterBlast

Lanthipeptide predictions

Lanthipeptides - No core peptides found.

Similar known gene clusters

Lanthipeptides

Core peptide predictions

No core peptides found.

NAQJ01000003.1 - Region 2 - NRPS-like

Download region GenBank file

Download region SVG

Location: 172,182 - 215,193 nt. (total: 43,012 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 172181 - 215193:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg20_155

Search NORINE for peptide: strict or relaxed

AMP-binding (14..381): X

NRPSPredictor2: gly, ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DfftIGiIYK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 60% (weak)

NAQJ01000006.1 - Region 1 - RiPP-like,lanthipeptide-class-ii

Download region GenBank file

Download region SVG

Location: 3,914 - 36,613 nt. (total: 32,700 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)
lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Lanthipeptides

KnownClusterBlast

Lanthipeptide predictions

Lanthipeptide(s) for ctg23_25 - Putative Class II

ctg23_16 leader / core peptide: MVTLKNDNVVGDRGDGAAAA - VGDhaARELVDGLVDhaDhaGRWIPCDhaDhaG
allorf_027582_027722 leader / core peptide: MRHYDAVAGS - RLPDAICRLDhaFIGCRLDhaDADhaVDhaAQRCDDhaVPVRADhaIV
allorf_027756_027830 leader / core peptide: LRKRVFFA - YWDNDhaRCPGLRVNRDhaDhb
allorf_023285_023395 leader / core peptide: LQEQTKVPHS - CVRVQDhbHPLLAMYGLDhbILVNDhaLDhaICF

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Similar known gene clusters

No matches found.

Lanthipeptides

Core peptide predictions

ctg23_16 - Class II

Cleavage pHMM score: -6.00

RODEO score: 0

Monoisotopic mass: 2241.2 Da

Molecular weight: 2242.5 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 2260.5 Da N = 1; 2278.5 Da N = 2; 2296.6 Da N = 3; 2314.6 Da N = 4

allorf_027582_027722 - Class II

Cleavage pHMM score: -3.90

RODEO score: 0

Monoisotopic mass: 3752.0 Da

Molecular weight: 3754.3 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3772.4 Da N = 1; 3790.4 Da N = 2; 3808.4 Da N = 3

allorf_027756_027830 - Class II

Cleavage pHMM score: -6.30

RODEO score: 0

Monoisotopic mass: 1868.9 Da

Molecular weight: 1870.0 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 1888.1 Da N = 1; 1906.1 Da N = 2

allorf_023285_023395 - Class II

Cleavage pHMM score: -7.20

RODEO score: 0

Monoisotopic mass: 2818.5 Da

Molecular weight: 2820.4 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 2838.4 Da N = 1; 2856.5 Da N = 2

NAQJ01000006.1 - Region 2 - RRE-containing,lanthipeptide-class-iii

Download region GenBank file

Download region SVG

Location: 70,633 - 100,289 nt. (total: 29,657 nt) Show pHMM detection rules used

lanthipeptide-class-iii: (micKC and not PKS_KS)
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Lanthipeptides

KnownClusterBlast

Lanthipeptide predictions

Lanthipeptides - No core peptides found.

Similar known gene clusters

No matches found.

Lanthipeptides

Core peptide predictions

No core peptides found.