MIBiG Protein Description MIBiG Cluster MiBiG Product % ID % Coverage BLAST Score E-value
ATP76243.1 NdaA BGC0001705 NRP + Polyketide 24.0 111.1 114.0 3.5e-25
CCM44336.1 Nonribosomal_peptide_synthetase BGC0001056 NRP + Polyketide:Modular type I + Polyketide:PUFA synthase or related 26.0 94.2 108.0 4.2e-23
AAF00961.1 mcyB BGC0001017 NRP + Polyketide:Modular type I 23.0 111.1 106.0 1.2e-22
AEO14743.1 NdaA BGC0000396 NRP 23.0 111.3 106.0 1.6e-22
AAO62587.1 peptide_sythetase BGC0001016 NRP + Polyketide 23.0 110.9 105.0 2.7e-22
ABD14711.1 cesA BGC0000320 NRP:Cyclic depsipeptide 23.0 104.3 103.0 8e-22
antaF putative_Acyl-CoA_ligase BGC0001455 NRP + Polyketide 25.0 106.2 103.0 1e-21
CAH10130.1 feruloyl-CoA_synthetase BGC0000268 Polyketide 24.0 103.4 102.0 2.3e-21
AOZ21320.1 SulM BGC0001790 NRP 26.0 106.2 101.0 5.2e-21
ANY58984.1 non-ribosomal_synthetase BGC0001615 NRP 23.0 103.6 100.0 8.8e-21
BBD17766.1 AMP-ligase BGC0001919 NRP + Polyketide 25.0 107.5 100.0 8.8e-21
BBD17745.1 AMP-ligase BGC0001918 NRP + Polyketide 24.0 107.5 99.0 1.5e-20
AFV52184.1 acyl-CoA_synthetase/P450_monooxygenase BGC0000081 Polyketide:Iterative type I + Polyketide:Enediyne type I 25.0 100.4 99.0 2e-20
CAD29799.1 microcystin_synthetase BGC0001015 NRP + Polyketide 23.0 102.3 99.0 2e-20
ABA23460.1 Amino_acid_adenylation BGC0000427 NRP 22.0 103.6 97.0 4.4e-20
AJI44176.1 nonribosomal_peptide_synthetase BGC0001193 NRP 25.0 104.3 96.0 9.7e-20
CAD29798.1 peptide_synthetase BGC0001015 NRP + Polyketide 26.0 84.2 96.0 1.7e-19
AQX14441.1 EM5400_NRPS_scaffold BGC0001671 NRP 23.0 111.1 95.0 2.2e-19
ALV82356.1 CDA_peptide_synthetase_I BGC0001370 NRP 23.0 103.6 95.0 2.8e-19
AGY30674.1 Ann1 BGC0001298 Polyketide 24.0 97.4 94.0 3.7e-19
AQH32485.1 peptide_synthetase BGC0001667 NRP + Polyketide 23.0 111.1 94.0 3.7e-19
AWI62626.1 nonribosomal_peptide_synthetase BGC0001943 NRP 24.0 107.7 94.0 6.3e-19
PHM26612.1 pvdj BGC0001130 NRP + Polyketide 23.0 108.3 92.0 1.4e-18
AWX24488.1 acyl-CoA_ligase BGC0001695 NRP 23.0 107.2 92.0 1.4e-18
AFO85453.1 non-ribosomal_peptide_synthetase BGC0000391 NRP 25.0 104.7 92.0 2.4e-18
WP_044618979.1 non-ribosomal_peptide_synthetase BGC0001791 NRP 24.0 106.8 91.0 3.1e-18
BBE36469.1 amino_acid_adenylation_domain-containing_protein BGC0001922 Polyketide 25.0 106.8 91.0 3.1e-18
AWS21276.1 amino_acid_adenyltransferase BGC0001934 Polyketide 26.0 72.3 91.0 3.1e-18
AZY92000.1 proline_adenylation_protein BGC0002022 Polyketide 26.0 72.3 91.0 3.1e-18
BAP34707.1 AMP-dependent_synthetase_and_ligase BGC0000078 Polyketide 22.0 109.8 91.0 5.3e-18
AAC06346.1 bacitracin_synthetase_1 BGC0000310 NRP 22.0 101.9 90.0 7e-18
CAD70195.1 non-ribosomal_peptide_synthetase BGC0001047 NRP + Polyketide 23.0 106.2 90.0 7e-18
ACZ55942.1 non-ribosomal_peptide_synthetase BGC0000302 NRP 22.0 105.1 89.0 1.2e-17
ACC81021.1 non-ribosomal_peptide_synthetase BGC0001479 NRP 23.0 105.1 89.0 1.2e-17
ADI58645.1 Amide_synthase BGC0000187 Polyketide:Type II 26.0 73.6 89.0 2e-17
ATY72525.1 non-ribosomal_peptide_synthetase BGC0001574 NRP 24.0 104.9 89.0 2e-17
WP_063738219.1 amino_acid_adenylation_domain-containing_protein BGC0002010 NRP + Polyketide 24.0 113.2 89.0 2e-17
APZ78782.1 nonribosomal_peptide_synthetase BGC0001426 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 23.0 106.0 88.0 3.5e-17
AVI26393.1 nonribosomal_peptide_synthase BGC0001800 NRP + Polyketide 23.0 104.5 88.0 3.5e-17
ABL74945.1 NRPS BGC0001048 NRP:Glycopeptide + Polyketide:Modular type I + Saccharide:Hybrid/tailoring 24.0 107.7 87.0 5.9e-17
APZ78756.1 nonribosomal_peptide_synthetase BGC0001423 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 22.0 103.0 87.0 7.7e-17
QCE20609.1 AsmN BGC0001961 NRP 25.0 104.9 87.0 7.7e-17
BAH43870.1 putative_linear_pentadecapeptide_gramicidin_synthetase_LgrB BGC0000367 NRP 22.0 104.7 86.0 1.3e-16
AGC09519.1 AMP-dependent_synthetase/ligase BGC0001183 Polyketide 24.0 104.5 86.0 1.3e-16
WP_018540603.1 non-ribosomal_peptide_synthetase BGC0001332 NRP + Polyketide 22.0 104.3 86.0 1.3e-16
ACM79806.1 ZmaB BGC0001059 NRP + Polyketide 21.0 105.1 86.0 1.7e-16
APZ78768.1 nonribosomal_peptide_synthetase BGC0001425 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 24.0 102.6 86.0 1.7e-16
ABR67749.1 CmnF BGC0000316 NRP 25.0 75.7 85.0 2.2e-16
APZ78795.1 nonribosomal_peptide_synthetase BGC0001427 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 23.0 106.0 85.0 2.2e-16
CCJ67639.1 TaaD BGC0000447 NRP:Lipopeptide 23.0 104.3 84.0 3.8e-16
APZ78769.1 nonribosomal_peptide_synthetase BGC0001425 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 23.0 106.0 84.0 3.8e-16
BAI23334.1 putative_non-ribosomal_peptide_synthetase BGC0000949 NRP 26.0 107.2 84.0 5e-16
ABL74936.1 NRPS BGC0001048 NRP:Glycopeptide + Polyketide:Modular type I + Saccharide:Hybrid/tailoring 22.0 103.2 84.0 5e-16
ACG60782.1 NRPS(C/A/PCP/C/A/PCP) BGC0001058 NRP:Glycopeptide + Polyketide:Modular type I + Saccharide:Hybrid/tailoring 25.0 74.6 84.0 5e-16
AAT09805.1 NocB BGC0000395 NRP 23.0 104.9 84.0 6.5e-16
AAN85501.1 nonribosomal_peptide_synthetase BGC0001101 NRP + Polyketide:Modular type I + Polyketide:Trans-AT type I 23.0 106.2 84.0 6.5e-16
ATL73045.1 amino_acid_adenylation_domain_protein BGC0001807 NRP + Polyketide 23.0 104.5 84.0 6.5e-16
APZ78794.1 nonribosomal_peptide_synthetase BGC0001427 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 24.0 103.8 83.0 8.5e-16
ANI24100.1 nonribosomal_peptide_synthetase BGC0001235 NRP + Polyketide 23.0 105.5 82.0 1.5e-15
AIL50191.1 putative_amide_synthetase BGC0000213 Polyketide:Type II 23.0 104.7 82.0 1.9e-15
ADQ55476.1 NRPS BGC0000350 NRP:Beta-lactam 22.0 110.4 82.0 1.9e-15
CAG69516.1 putative_non-ribosomal_peptide_synthetase_with_condensation,_AMP-binding_and_phosphopantetheine-binding_domains BGC0000352 NRP:NRP siderophore 21.0 106.0 82.0 1.9e-15
CAJ76286.1 putative_non-ribosomal_peptide_synthetase BGC0000972 NRP + Polyketide:Modular type I + Polyketide:Trans-AT type I 23.0 103.6 82.0 1.9e-15
APZ78744.1 nonribosomal_peptide_synthetase BGC0001422 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 23.0 106.0 82.0 1.9e-15
APZ78808.1 nonribosomal_peptide_synthetase BGC0001428 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 24.0 102.6 82.0 1.9e-15
RAT94090.1 NRPS BGC0001469 NRP 22.0 106.2 82.0 1.9e-15
CAJ96471.1 non-ribosomal_peptide_synthetase BGC0000330 NRP:NRP siderophore 23.0 105.3 82.0 2.5e-15
CAQ34921.1 nonribosomal_peptide_synthetase BGC0000986 NRP + Polyketide 22.0 106.0 82.0 2.5e-15
ABS74207.1 fengycin_synthetase_C BGC0001095 NRP 22.0 102.1 82.0 2.5e-15
APZ78728.1 nonribosomal_peptide_synthetase BGC0001421 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 23.0 102.8 81.0 3.2e-15
APZ78834.1 nonribosomal_peptide_synthetase BGC0001430 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 23.0 105.8 81.0 3.2e-15
ARU08063.1 mlcA BGC0001448 NRP:Ca+-dependent lipopeptide 23.0 106.4 81.0 3.2e-15
CZT62785.1 Non-ribosomal_peptide_synthase,_involved_in_Hassallidin_biosynthesis BGC0001614 NRP 23.0 106.2 81.0 3.2e-15
CAL80821.1 sylD-like_NRPS/PKS BGC0000997 NRP + Polyketide 23.0 112.8 81.0 4.2e-15
WP_078857610.1 non-ribosomal_peptide_synthetase BGC0001368 NRP 23.0 103.0 81.0 4.2e-15
AAC32047.1 FxbB BGC0000351 NRP 23.0 108.5 81.0 5.5e-15
AGZ15455.1 non-ribosomal_peptide_synthetase BGC0001036 NRP + Polyketide 22.0 106.0 81.0 5.5e-15
APZ78781.1 nonribosomal_peptide_synthetase BGC0001426 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 23.0 102.6 81.0 5.5e-15
AEH42484.1 adenylation_for_L-proline BGC0000032 Polyketide 23.0 103.0 80.0 7.2e-15
ADB02873.1 AzicV BGC0000202 Polyketide 25.0 89.3 80.0 7.2e-15
ABV56588.1 KtzH BGC0000378 NRP 22.0 106.0 80.0 7.2e-15
ABV56582.1 KtzB BGC0000378 NRP 23.0 103.6 80.0 7.2e-15
AJF34464.1 Txo2 BGC0001207 NRP 22.0 103.6 80.0 7.2e-15
QED88054.1 nonribosomal_peptide_synthetase BGC0001967 NRP 24.0 106.8 80.0 7.2e-15
AAG04385.1 probable_coenzyme_A_ligase BGC0000922 Other 27.0 75.7 80.0 9.4e-15
ADN26251.1 ATP-dependent_adenylase BGC0000951 NRP 23.0 109.6 80.0 9.4e-15
APZ78809.1 nonribosomal_peptide_synthetase BGC0001428 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 22.0 105.3 80.0 9.4e-15
APZ78855.1 nonribosomal_peptide_synthetase BGC0001432 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 23.0 103.2 80.0 9.4e-15
AAN32981.1 BarG BGC0000962 NRP + Polyketide:Modular type I 22.0 106.8 79.0 1.2e-14
CCJ67648.1 JagD BGC0001127 NRP 22.0 105.8 79.0 1.2e-14
CAI94705.1 putative_acid_AMP_ligase BGC0000141 Polyketide 25.0 60.3 79.0 1.6e-14
ABA73955.1 putative_non-ribosomal_peptide_synthetase BGC0001842 NRP:Lipopeptide 22.0 105.5 79.0 1.6e-14
WP_047197779.1 non-ribosomal_peptide_synthetase BGC0002003 NRP 21.0 104.5 79.0 2.1e-14
BAI63283.1 putative_non-ribosomal_peptide_synthetase BGC0000434 NRP 22.0 105.1 78.0 2.7e-14
ADY76667.1 non-ribosomal_peptide_synthetase BGC0000950 NRP:Uridylpeptide + Other:Nucleoside 25.0 104.5 78.0 2.7e-14
APZ78715.1 nonribosomal_peptide_synthetase BGC0001420 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 23.0 103.2 78.0 2.7e-14
AQM37584.1 nonribosomal_peptide_synthetase BGC0001424 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 22.0 102.8 78.0 2.7e-14
ABV56604.1 adenylation_domain_protein BGC0000378 NRP 22.0 106.2 78.0 3.6e-14
ABX37382.1 amino_acid_adenylation_domain_protein BGC0000984 NRP + Polyketide 23.0 103.6 78.0 3.6e-14
APZ78703.1 nonribosomal_peptide_synthetase BGC0001419 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 23.0 103.2 78.0 3.6e-14
ATY37591.1 BogD BGC0001532 NRP 22.0 103.0 78.0 3.6e-14
AXN93605.1 PuwA BGC0001953 NRP 23.0 106.0 78.0 3.6e-14
APZ78729.1 nonribosomal_peptide_synthetase BGC0001421 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 22.0 102.8 77.0 4.7e-14
CAJ14039.1 peptide_synthetase BGC0000406 NRP 22.0 105.8 77.0 6.1e-14
AAG02349.1 peptide_synthetase_NRPS11-10 BGC0000963 NRP:Glycopeptide + Polyketide:Modular type I + Saccharide:Hybrid/tailoring 23.0 89.3 77.0 6.1e-14
AOA33122.1 Nonribosomal_peptide_synthetase BGC0001346 NRP:Cyclic depsipeptide 22.0 104.7 77.0 6.1e-14
CCE28989.1 non-ribosomal_peptide_synthetase BGC0001365 NRP 25.0 101.1 77.0 6.1e-14
APZ78691.1 nonribosomal_peptide_synthetase BGC0001418 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 23.0 103.2 77.0 6.1e-14
QDA77045.1 polyketide_synthase/nonribosomal_peptide_synthetase BGC0002025 NRP 21.0 103.4 77.0 6.1e-14
ABV79988.1 ApnD BGC0000301 NRP 22.0 106.6 77.0 8e-14
AAZ55899.1 amino_acid_adenylation BGC0000359 NRP 23.0 104.3 77.0 8e-14
CBL93718.1 NRPS_didomain_PCP-C BGC0000360 NRP 23.0 113.4 77.0 8e-14
KGO40476.1 AMP-dependent_synthetase/ligase BGC0001205 Polyketide 24.0 109.4 77.0 8e-14
KFL51886.1 amino_acid_adenylation_protein BGC0001711 NRP + Polyketide 23.0 105.1 77.0 8e-14
AXN93592.1 PuwA BGC0001952 NRP 23.0 106.0 77.0 8e-14
QED55422.1 nonribosomal_peptide_synthetase BGC0001984 NRP 22.0 102.3 77.0 8e-14
QDA77059.1 polyketide_synthase/nonribosomal_peptide_synthetase BGC0002026 NRP 22.0 105.8 77.0 8e-14
ABF87031.1 non-ribosomal_peptide_synthetase/polyketide_synthase BGC0000393 NRP + Polyketide:Modular type I 22.0 106.2 76.0 1e-13
ALD82526.1 non-ribosomal_peptide_synthase BGC0001212 NRP + Polyketide 21.0 103.0 76.0 1e-13
BAQ25518.1 acyl-CoA_synthetase BGC0001288 Polyketide 28.0 71.6 76.0 1e-13
ACN69986.1 proline_adenyltransferase BGC0000079 Polyketide 23.0 102.3 76.0 1.4e-13
ABW71852.1 nonribosomal_peptide_synthetase BGC0000303 NRP 25.0 106.8 76.0 1.4e-13
AHB38497.1 non-ribosomal_peptide_synthetase BGC0000346 NRP + Polyketide:Modular type I 24.0 93.0 76.0 1.4e-13
AAU39359.1 lichenysin_synthase_LchAA BGC0000381 NRP 22.0 107.2 76.0 1.4e-13
AQM37583.1 nonribosomal_peptide_synthetase BGC0001424 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 23.0 102.6 76.0 1.4e-13
BAJ19066.1 L-lysine_activating_non-ribosomal_peptide_synthetase BGC0000288 NRP 24.0 108.5 76.0 1.8e-13
AFH75320.1 nonribosomal_peptide_synthetase BGC0000425 NRP:Cyclic depsipeptide 22.0 106.0 75.0 2.3e-13
AIW82277.1 PuwA BGC0001125 NRP + Polyketide 23.0 107.5 75.0 2.3e-13
APZ78679.1 nonribosomal_peptide_synthetase BGC0001417 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 23.0 102.6 75.0 2.3e-13
APZ78846.1 nonribosomal_peptide_synthetase BGC0001431 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 24.0 103.2 75.0 2.3e-13
BAO66530.1 nonribosomal_peptide_synthase BGC0000042 Polyketide 23.0 104.5 75.0 3e-13
AEH41789.1 HrmK BGC0000374 NRP:Cyclic depsipeptide 23.0 76.1 75.0 3e-13
CAG29032.1 nonribosomal_peptide_synthetase_(modules_3_to_6) BGC0001023 NRP + Polyketide:Modular type I 25.0 103.2 75.0 3e-13
AKD43757.1 HerL BGC0001349 NRP + Polyketide 22.0 106.2 75.0 3e-13
APZ78743.1 nonribosomal_peptide_synthetase BGC0001422 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 22.0 103.6 75.0 3e-13
APZ78822.1 nonribosomal_peptide_synthetase BGC0001429 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 25.0 103.2 75.0 3e-13
BAL15726.1 NRPS BGC0000432 NRP 24.0 108.1 74.0 4e-13
APZ78680.1 nonribosomal_peptide_synthetase BGC0001417 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 23.0 104.7 74.0 4e-13
WP_016638466.1 amino_acid_adenylation_domain-containing_protein BGC0001519 NRP + Polyketide 23.0 106.0 74.0 4e-13
BAP34718.1 AMP-dependent_synthetase_and_ligase BGC0000078 Polyketide 27.0 75.7 74.0 5.2e-13
APZ78755.1 nonribosomal_peptide_synthetase BGC0001423 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 22.0 103.0 74.0 5.2e-13
AAM80537.1 StaC BGC0000290 NRP:Glycopeptide 23.0 103.4 74.0 6.8e-13
ACZ55945.1 non-ribosomal_peptide_synthetase BGC0000302 NRP 23.0 109.4 74.0 6.8e-13
WP_107406787.1 non-ribosomal_peptide_synthetase BGC0001567 NRP 23.0 103.8 74.0 6.8e-13
AXG22420.1 proline_adenyltransferase BGC0002024 Polyketide 24.0 73.3 74.0 6.8e-13
AFH75321.1 nonribosomal_peptide_synthetase BGC0000425 NRP:Cyclic depsipeptide 22.0 104.5 73.0 1.2e-12
EFE73308.1 non-ribosomal_peptide_synthetase BGC0000431 NRP:Cyclic depsipeptide 23.0 106.4 73.0 1.2e-12
ACG60773.1 NRPS(C/A/PCP) BGC0001058 NRP:Glycopeptide + Polyketide:Modular type I + Saccharide:Hybrid/tailoring 21.0 105.1 73.0 1.2e-12
ALA09366.1 AMP-dependent_synthetase_and_ligase BGC0001303 Polyketide 23.0 107.2 73.0 1.2e-12
AXN93575.1 PuwA BGC0001950 NRP 23.0 107.5 73.0 1.2e-12
AXN93584.1 PuwA BGC0001951 NRP 23.0 107.5 73.0 1.2e-12
ACO94492.1 NRPS_adenylation_domain_protein BGC0000097 Polyketide:Modular type I 22.0 104.9 72.0 1.5e-12
CAE16560.1 BGC0000196 Polyketide:Type II 23.0 92.5 72.0 1.5e-12
CAM02313.1 putative_non-ribosomal_peptide_synthetase BGC0000349 NRP 23.0 103.2 72.0 1.5e-12
AAZ55898.1 amino_acid_adenylation BGC0000359 NRP 22.0 106.6 72.0 1.5e-12
AAN85530.1 nonribosomal_peptide_synthetase,_discrete_adenylation_domain BGC0001101 NRP + Polyketide:Modular type I + Polyketide:Trans-AT type I 24.0 105.1 72.0 1.5e-12
ADN26252.1 peptide_synthetase BGC0000951 NRP 24.0 103.4 72.0 2e-12
WP_051700122.1 non-ribosomal_peptide_synthetase BGC0001368 NRP 22.0 101.1 72.0 2e-12
OAL11475.1 non-ribosomal_peptide_synthetase_module BGC0001570 NRP 25.0 104.1 72.0 2e-12
ACO94464.1 NRPS_adenylation_domain_protein BGC0000029 Polyketide:Modular type I 23.0 105.1 72.0 2.6e-12
AAY93356.2 non-ribosomal_peptide_synthetase_PvdI BGC0000413 NRP 23.0 106.8 71.0 3.4e-12
AGZ03650.1 sevA BGC0000426 NRP 21.0 107.7 71.0 3.4e-12
AGZ15459.1 putative_non-ribosomal_peptide_synthetase BGC0001036 NRP + Polyketide 22.0 107.2 71.0 3.4e-12
CCA89328.1 mixed_trans-AT_type_I_polyketide_synthase/nonribosomal_peptide_synthetase BGC0001111 NRP + Polyketide:Trans-AT type I 23.0 104.3 71.0 3.4e-12
ATY37588.1 BogA BGC0001532 NRP 22.0 107.0 71.0 3.4e-12
AHD05614.1 putative_non-ribosomal_peptide_ligase/_polyketide_synthase_hybrid BGC0001033 NRP + Polyketide 23.0 106.4 71.0 4.4e-12
AFR69331.1 nonribosomal_peptide_synthetase_SpiA BGC0001045 NRP:Cyclic depsipeptide + Polyketide:Modular type I 21.0 102.8 71.0 4.4e-12
OLZ52457.1 non-ribosomal_peptide_synthetase BGC0001462 NRP:Glycopeptide 22.0 103.4 71.0 4.4e-12
AAP92496.1 nonribosomal_peptide_synthetase BGC0000458 NRP 23.0 109.2 71.0 5.7e-12
AQZ26587.1 obafluorin_dimodular_nonribosomal_peptide_synthetase BGC0001710 NRP 23.0 78.9 71.0 5.7e-12
AWI62627.1 nonribosomal_peptide_synthetase BGC0001943 NRP 22.0 105.3 71.0 5.7e-12
CAB53322.1 putative_peptide_synthetase BGC0000325 NRP 23.0 106.4 70.0 7.5e-12
ABC34483.1 nonribosomal_peptide_synthetase,_putative BGC0000961 NRP + Polyketide 22.0 102.3 70.0 7.5e-12
ATY69584.1 hybrid_nonribosomal_peptide_synthetase/type_I_polyketide_synthase BGC0001823 NRP + Polyketide 23.0 103.2 70.0 7.5e-12
AAF17281.1 nosD BGC0001028 Polyketide + NRP:Cyclic depsipeptide 23.0 103.2 70.0 9.8e-12
AFR69334.1 nonribosomal_peptide_synthetase_SpiDE1 BGC0001045 NRP:Cyclic depsipeptide + Polyketide:Modular type I 23.0 78.3 70.0 9.8e-12
ACN39015.1 putative_nonribosomal_peptide_synthetase_TomB BGC0000448 NRP 23.0 108.3 69.0 1.3e-11
ABA59548.1 NRPS BGC0000453 NRP:Cyclic depsipeptide 22.0 102.8 69.0 1.3e-11
AAG28698.1 FadD BGC0000649 Terpene 24.0 76.5 69.0 1.3e-11
ABC34137.1 peptide_synthetase,_putative BGC0000961 NRP + Polyketide 21.0 104.1 69.0 1.3e-11
ABC36785.1 peptide_synthetase,_putative BGC0000964 NRP:Cyclic depsipeptide + Polyketide:Trans-AT type I 24.0 77.4 69.0 1.3e-11
AKP45400.1 CysL BGC0001413 NRP 24.0 72.7 69.0 1.3e-11
KPN93065.1 NunD BGC0001416 NRP 23.0 107.2 69.0 1.3e-11
AWI62628.1 nonribosomal_peptide_synthetase BGC0001943 NRP 23.0 108.3 69.0 1.3e-11
BAH22762.1 nonribosomal_peptide_synthetase BGC0001018 NRP + Polyketide 21.0 106.8 69.0 1.7e-11
AQI70_32580 BGC0001561 NRP 23.0 97.9 69.0 1.7e-11
CBA11570.1 non-ribosomal_peptide_synthetase BGC0001046 NRP + Polyketide:Modular type I + Saccharide:Hybrid/tailoring 23.0 106.0 69.0 2.2e-11
WP_041826607.1 non-ribosomal_peptide_synthetase BGC0001792 NRP 22.0 104.7 69.0 2.2e-11
ABY83142.1 Azi3 BGC0000960 NRP + Polyketide 23.0 74.6 68.0 2.8e-11
APZ78856.1 nonribosomal_peptide_synthetase BGC0001432 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 22.0 104.9 68.0 2.8e-11
YP_856990.1 nonribosomal_peptide_synthetase BGC0001502 NRP 23.0 104.7 68.0 2.8e-11
ABB69752.1 PlaP4 BGC0000654 Terpene + Saccharide:Hybrid/tailoring 24.0 73.3 68.0 3.7e-11
CBK62746.1 BGC0001115 NRP + Polyketide 21.0 107.5 68.0 3.7e-11
APZ78716.1 nonribosomal_peptide_synthetase BGC0001420 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 22.0 104.5 68.0 3.7e-11
ANH11404.1 SceI BGC0001908 Polyketide 22.0 108.7 68.0 3.7e-11
APU91750.1 Non-Ribosomal_Peptide_Synthetase BGC0001806 NRP 22.0 106.2 68.0 3.7e-11
ADN26257.1 ATP-dependent_adenylase BGC0000951 NRP 24.0 76.1 67.0 4.8e-11
AAG02364.1 peptide_synthetase_NRPS2-1 BGC0000963 NRP:Glycopeptide + Polyketide:Modular type I + Saccharide:Hybrid/tailoring 23.0 104.9 67.0 4.8e-11
ADM34138.1 non-ribosomal_peptide_synthetase BGC0001084 NRP + Terpene + Alkaloid 23.0 80.4 67.0 4.8e-11
APZ78704.1 nonribosomal_peptide_synthetase BGC0001419 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 22.0 104.5 67.0 4.8e-11
EWS95124.1 hypothetical_protein BGC0000306 NRP:Lipopeptide 25.0 74.0 67.0 6.3e-11
AAF08797.1 MycC BGC0001103 NRP + Polyketide 21.0 103.0 67.0 6.3e-11
EFL06867.1 predicted_protein BGC0000300 NRP 22.0 102.6 67.0 8.3e-11
XP_020057667.1 hypothetical_protein BGC0001718 NRP 24.0 92.8 67.0 8.3e-11
EFG10344.1 Non-ribosomal_peptide_synthetase BGC0000373 NRP 22.0 105.3 66.0 1.1e-10
AAL06681.1 A-domain_type_II_peptide_synthetase BGC0000965 Polyketide:Iterative type I + Polyketide:Enediyne type I 24.0 78.3 66.0 1.1e-10
ALU98443.1 hypothetical_protein BGC0001397 NRP + Polyketide 24.0 78.3 66.0 1.1e-10
APZ78692.1 nonribosomal_peptide_synthetase BGC0001418 NRP:Cyclic depsipeptide + Polyketide:Iterative type I 24.0 76.1 66.0 1.1e-10
BAH43871.1 truncated_linear_pentadecapeptide_gramicidin_synthetase_LgrC BGC0000367 NRP 21.0 105.3 66.0 1.4e-10
CDG76959.1 non-ribosomal_peptide_synthetase,_terminal_component BGC0001805 NRP 23.0 96.2 66.0 1.4e-10
ABP57748.1 DepD BGC0000993 NRP:Cyclic depsipeptide + Polyketide:Modular type I 23.0 105.5 66.0 1.4e-10
BAD55613.1 putative_non-ribosomal_peptide_synthetase BGC0001027 NRP + Polyketide 21.0 104.1 66.0 1.4e-10
AJV88376.1 MfnD BGC0001214 NRP 23.0 105.8 66.0 1.4e-10
AGC65516.1 NRPS/PKS_hybrid BGC0001050 NRP:Lipopeptide + Polyketide:Trans-AT type I 22.0 105.3 66.0 1.8e-10
sipL7 AMP-dependent_synthetase_and_ligase BGC0001452 Polyketide 26.0 77.6 65.0 2.4e-10
AVR48535.1 CusC BGC0001564 NRP + Polyketide 22.0 107.2 65.0 2.4e-10
ABR67758.1 CmnO BGC0000316 NRP 25.0 74.8 65.0 3.1e-10
AIE77059.1 peptide_synthetase BGC0000418 NRP 23.0 104.5 65.0 3.1e-10
CAJ45639.1 vanchrobactin_non_ribosomal_peptide_synthetase BGC0000454 NRP 21.0 78.9 65.0 3.1e-10
BAV56002.1 ATP-dependent_ligase BGC0001597 Polyketide 23.0 76.5 65.0 3.1e-10
AQZ71347.1 hypothetical_protein BGC0001635 NRP + Polyketide 23.0 102.8 65.0 3.1e-10
WP_078586793.1 non-ribosomal_peptide_synthetase BGC0001760 NRP 22.0 103.2 65.0 3.1e-10
ABP55216.1 AMP-dependent_synthetase_and_ligase BGC0000142 Polyketide 23.0 75.5 64.0 4.1e-10
ABD65956.1 nonribosomal_peptide_synthetase BGC0000341 NRP 22.0 103.6 64.0 4.1e-10
BAP16697.1 nonribosomal_peptide_synthetase BGC0000376 NRP 24.0 99.8 64.0 4.1e-10
ADZ45333.1 NRPS/PKS_hybrid BGC0001020 NRP + Polyketide 22.0 102.8 64.0 4.1e-10
AWR88407.1 putative_AMP-dependent_synthetase_and_ligase BGC0001522 Polyketide 25.0 77.6 64.0 4.1e-10
CBL93720.1 NRPS_didomain_PCP-A BGC0000360 NRP 24.0 74.4 64.0 5.4e-10
AGE11891.1 nonribosomal_peptide_synthetase BGC0000366 NRP 23.0 75.9 64.0 5.4e-10
AGC83576.1 NRPS BGC0000818 NRP 21.0 108.7 64.0 5.4e-10
AAO39110.1 AdmP BGC0000956 NRP:Beta-lactam + Polyketide:Type II 21.0 104.3 64.0 5.4e-10
AGS77309.1 NRPS_modules_4-6 BGC0001178 NRP:Glycopeptide 22.0 102.8 64.0 5.4e-10
AKA59440.1 non-ribosomal_peptide_synthetase BGC0001202 NRP + Polyketide 22.0 106.6 64.0 5.4e-10
ARO38317.1 nonribosomal_peptide_synthetase BGC0001560 NRP + Polyketide 23.0 91.9 64.0 5.4e-10
ANY94451.1 A-domain_type_II_peptide_synthetase BGC0001584 Polyketide 25.0 78.7 64.0 5.4e-10
AQM58286.1 non-ribosomal_peptide_synthase BGC0001816 NRP + Polyketide 22.0 109.8 64.0 5.4e-10
QCX41915.1 Mhr9 BGC0001956 Polyketide 24.0 77.8 64.0 5.4e-10
AGN74885.1 nonribosomal_peptide_synthetase BGC0000459 NRP:Cyclic depsipeptide + Polyketide:Trans-AT type I 24.0 95.1 64.0 7e-10
ABC39418.1 dihydroaeruginoic_acid_synthetase BGC0000964 NRP:Cyclic depsipeptide + Polyketide:Trans-AT type I 22.0 98.7 64.0 7e-10
CAJ76290.1 putative_non-ribosomal_peptide_synthase BGC0000972 NRP + Polyketide:Modular type I + Polyketide:Trans-AT type I 21.0 105.5 64.0 7e-10
CDG12864.1 non-ribosomal_peptide_synthetase BGC0001415 NRP 24.0 98.3 64.0 7e-10
ATD51280.1 nonribosomal_peptide_synthase BGC0001650 NRP 23.0 109.6 64.0 7e-10
QCX41944.1 Amc7 BGC0001958 Other 24.0 77.2 64.0 7e-10
QBC75023.1 non-ribosomal_peptide_synthetase BGC0001968 NRP 21.0 100.2 64.0 7e-10
AEC14346.1 nonribosomal_peptide_synthetase BGC0000377 NRP 22.0 103.6 63.0 9.1e-10
AAY91421.3 non-ribosomal_peptide_synthetase_OfaC BGC0000399 NRP:Cyclic depsipeptide 21.0 100.9 63.0 9.1e-10
AEF33078.1 dimodular_nonribosomal_peptide_synthetase BGC0001039 NRP + Polyketide 22.0 107.5 63.0 9.1e-10
WP_013184462.1 non-ribosomal_peptide_synthetase BGC0001716 NRP 23.0 104.7 63.0 9.1e-10
EJK79843.1 amino_acid_adenylation_enzyme/thioester_reductase_family_protein BGC0000436 NRP 21.0 106.8 63.0 1.2e-09
CCA29203.1 non-ribosomal_peptide_synthetase/polyketide_synthase BGC0000955 NRP + Polyketide:Modular type I 21.0 98.7 63.0 1.2e-09
ACR78148.1 BSLS BGC0000312 NRP 22.0 112.6 62.0 1.6e-09
AFL68053.1 amino_acid_adenylation_enzyme/thioester_reductase_family_protein BGC0001524 NRP + Polyketide 22.0 102.1 62.0 1.6e-09
ctg1_orf1265 BGC0001752 NRP 22.0 110.9 62.0 1.6e-09
AHZ20774.1 non-ribosomal_peptide_synthase BGC0000369 NRP + Saccharide:Hybrid/tailoring 21.0 105.3 62.0 2e-09
CCP45171.1 Phenyloxazoline_synthase_MbtB_(phenyloxazoline_synthetase) BGC0001021 NRP + Polyketide 24.0 74.6 62.0 2e-09
WP_051206727.1 non-ribosomal_peptide_synthetase BGC0001467 NRP:Cyclic depsipeptide + Polyketide:Modular type I 21.0 90.8 62.0 2e-09
AEH41793.1 HrmO BGC0000374 NRP:Cyclic depsipeptide 24.0 110.2 62.0 2.7e-09
ADJ63842.1 Serobactin_synthetase BGC0000424 NRP:NRP siderophore 21.0 110.7 62.0 2.7e-09
ATJ04411.1 NRPS,_TomB_binding BGC0001637 NRP 24.0 96.8 62.0 2.7e-09
BAW27705.1 ligase BGC0001764 NRP 25.0 79.1 62.0 2.7e-09
WP_024483797.1 amino_acid_adenylation_domain-containing_protein BGC0002002 NRP 21.0 105.8 62.0 2.7e-09
ABX71145.1 Lcz28 BGC0000237 Polyketide 24.0 95.3 61.0 3.5e-09
ABX71111.1 Lct28 BGC0000238 Polyketide 23.0 105.1 61.0 3.5e-09
MAA_10043 non-ribosomal_peptide_synthetase BGC0000337 NRP 23.0 111.1 61.0 3.5e-09
BAP16699.1 nonribosomal_peptide_synthetase BGC0000376 NRP 21.0 105.8 61.0 3.5e-09
EFL06864.1 non-ribosomal_peptide_synthetase BGC0000300 NRP 22.0 74.0 61.0 4.5e-09
AEA30273.1 peptide_synthetase BGC0000429 Polyketide + NRP:Cyclic depsipeptide 22.0 109.4 61.0 5.9e-09
AAO39104.1 AdmJ BGC0000956 NRP:Beta-lactam + Polyketide:Type II 22.0 80.2 61.0 5.9e-09
AHD05617.1 putative_non-ribosomal_peptide_ligase_domain_protein BGC0001033 NRP + Polyketide 21.0 108.5 61.0 5.9e-09
BAB69700.1 iturin_A_synthetase_C BGC0001098 NRP + Polyketide 21.0 103.8 61.0 5.9e-09
AKA59431.1 benzoate-CoA_ligase BGC0001202 NRP + Polyketide 26.0 74.2 61.0 5.9e-09
ABB69081.1 putative_L-prolyl-AMP_ligase BGC0000260 Polyketide 21.0 98.7 60.0 7.7e-09
AAL65279.1 QbsL BGC0000925 Other 23.0 104.5 60.0 7.7e-09
ATU31794.1 NRPS BGC0001814 NRP 23.0 99.8 60.0 7.7e-09
QED88055.1 nonribosomal_peptide_synthetase BGC0001967 NRP 23.0 96.8 60.0 7.7e-09
CAD70194.1 non-ribosomal_peptide_synthetase BGC0001047 NRP + Polyketide 22.0 103.6 60.0 1e-08
ATY69568.1 adenylation_protein BGC0001611 NRP + Polyketide 21.0 111.9 60.0 1e-08
AIG79241.1 Hypothetical_protein BGC0000419 Saccharide + NRP:Glycopeptide 22.0 103.8 59.0 1.3e-08
AAN85522.1 hybrid_nonribosomal_peptide_synthetase_/_polyketide_synthase BGC0001101 NRP + Polyketide:Modular type I + Polyketide:Trans-AT type I 21.0 102.3 59.0 1.3e-08
BAR73011.1 putative_ATP-dependent_aminoacyl-ACP_synthetase BGC0001194 Polyketide 23.0 98.7 59.0 1.3e-08
ARU08073.1 mlcK BGC0001448 NRP:Ca+-dependent lipopeptide 22.0 103.8 59.0 1.7e-08
WP_015507662.1 non-ribosomal_peptide_synthetase BGC0001792 NRP 22.0 106.0 59.0 1.7e-08
CAJ96468.1 non-ribosomal_peptide_synthetase BGC0000330 NRP:NRP siderophore 21.0 111.5 59.0 2.3e-08
AGN74898.1 nonribosomal_peptide_synthetase BGC0000459 NRP:Cyclic depsipeptide + Polyketide:Trans-AT type I 23.0 98.7 59.0 2.3e-08
ADY76664.1 non-ribosomal_peptide_synthetase BGC0000950 NRP:Uridylpeptide + Other:Nucleoside 22.0 106.8 59.0 2.3e-08
ABP57745.1 DepA BGC0000993 NRP:Cyclic depsipeptide + Polyketide:Modular type I 22.0 74.8 59.0 2.3e-08
AJV88377.1 MfnE BGC0001214 NRP 23.0 86.4 59.0 2.3e-08
ATQ39428.1 cyclosporin_C_synthetase BGC0001565 NRP 23.0 87.6 59.0 2.3e-08
AAF00957.1 mcyG BGC0001017 NRP + Polyketide:Modular type I 22.0 94.0 58.0 3.8e-08
ADH04660.1 TugD BGC0001342 NRP + Polyketide 22.0 97.2 58.0 3.8e-08
WP_015507663.1 non-ribosomal_peptide_synthase BGC0001792 NRP 23.0 105.5 57.0 5e-08
CBL93716.1 NRPS_A-domain BGC0000360 NRP 25.0 76.1 57.0 6.6e-08
ACY13414.1 amino_acid_adenylation_domain_protein BGC0001367 NRP + Polyketide 22.0 91.7 57.0 6.6e-08
QCE20608.1 AsmM BGC0001961 NRP 23.0 104.3 57.0 8.6e-08
ABI22132.1 putative_non-ribosomal_peptide_synthetase BGC0000422 NRP 22.0 75.3 56.0 1.1e-07
AFK57212.1 DidA BGC0000985 Polyketide + NRP:Cyclic depsipeptide 22.0 105.3 56.0 1.1e-07
WP_019634550.1 type_I_polyketide_synthase BGC0001443 NRP + Polyketide 21.0 104.1 56.0 1.1e-07
CAJ34370.1 NRPS_protein BGC0000445 NRP:Cyclic depsipeptide 21.0 92.5 56.0 1.5e-07
AOC89001.1 putative_nonribosomal_peptide_synthetase BGC0001652 NRP 22.0 105.8 56.0 1.5e-07
ADH04641.1 TgaC BGC0001051 NRP + Polyketide:Modular type I 22.0 94.7 56.0 1.9e-07
CAC48369.1 peptide_synthetase BGC0000311 NRP 24.0 105.8 55.0 2.5e-07
AHJ31215.1 Long-chain-fatty-acid--CoA_ligase BGC0000430 NRP + Polyketide:Modular type I 23.0 97.9 55.0 2.5e-07
CAJ76289.1 putative_hybrid_non-ribosomal_peptide-polyketide_synthetase BGC0000972 NRP + Polyketide:Modular type I + Polyketide:Trans-AT type I 22.0 91.0 55.0 2.5e-07
AAK81826.1 peptide_synthetase BGC0000326 NRP 21.0 91.0 55.0 3.3e-07
AEG64689.1 LpmA BGC0000379 NRP 24.0 77.2 55.0 3.3e-07
ADZ24999.1 non-ribosomal_peptide_synthase BGC0000380 NRP + Polyketide:Modular type I 24.0 98.9 55.0 3.3e-07
AAF86395.1 FkbP BGC0000994 NRP + Polyketide 25.0 83.4 55.0 3.3e-07
BAD55612.1 non-ribosomal_peptide_synthetase BGC0001027 NRP + Polyketide 22.0 100.9 55.0 3.3e-07
AGO86662.1 equisetin_synthetase BGC0001255 NRP + Polyketide 21.0 102.3 55.0 3.3e-07
WP_051462298.1 non-ribosomal_peptide_synthetase BGC0001873 NRP:Lipopeptide 21.0 110.2 55.0 3.3e-07
EAU36744.1 predicted_protein BGC0000292 NRP 23.0 81.4 54.0 4.2e-07
AAV66110.2 fusaridione_A_synthetase BGC0000992 NRP + Polyketide 23.0 114.1 54.0 4.2e-07
WP_019634554.1 AMP-binding_protein BGC0001443 NRP + Polyketide 22.0 107.5 54.0 4.2e-07
AQM58288.1 non-ribosomal_peptide_synthase BGC0001816 NRP + Polyketide 21.0 108.7 54.0 4.2e-07
ATY69590.1 adenylation_protein BGC0001823 NRP + Polyketide 24.0 74.0 54.0 4.2e-07
QCT05762.1 Tri29 BGC0001983 Other 23.0 72.1 54.0 4.2e-07
EJK79842.1 amino_acid_adenylation_enzyme/thioester_reductase_family_protein BGC0000436 NRP 23.0 74.8 54.0 5.5e-07
BAH04161.1 putative_non-ribosomal_peptide_synthetase BGC0000450 NRP 21.0 92.3 54.0 5.5e-07
CAD91220.1 putative_non-ribosomal_peptide_synthetase,_modules_1-2 BGC0000289 NRP:Glycopeptide + Saccharide:Hybrid/tailoring 21.0 106.2 54.0 7.2e-07
AHH53507.1 non-ribosomal_peptide_synthetase BGC0000439 NRP:Ca+-dependent lipopeptide 21.0 95.3 54.0 7.2e-07
ctg1_orf00001 BGC0000901 Other 21.0 83.4 54.0 7.2e-07
ALV86868.1 Tlo22 BGC0001406 NRP 21.0 109.0 54.0 7.2e-07
AAL61889.1 unknown BGC0001411 Saccharide 23.0 81.7 54.0 7.2e-07
AQH32483.1 hybrid_peptide_synthetase/polyketide_synthase BGC0001667 NRP + Polyketide 30.0 22.0 54.0 7.2e-07
AET98905.1 putative_non-ribosomal_peptide_synthetase BGC0000415 NRP 21.0 92.3 53.0 1.2e-06
CBG75492.1 putative_NRPS/siderophore_biosynthesis_protein BGC0000423 NRP 22.0 76.1 53.0 1.2e-06
CDG12865.1 non-ribosomal_peptide_synthetase BGC0001415 NRP 21.0 89.6 53.0 1.2e-06
ATD51278.1 nonribosomal_peptide_synthase BGC0001650 NRP 22.0 78.3 52.0 1.6e-06
AAC68816.1 FK506_peptide_synthetase BGC0000353 NRP 24.0 78.3 52.0 2.1e-06
AEG64697.1 LpmC BGC0000379 NRP 22.0 107.5 52.0 2.1e-06
AAO56329.1 non-ribosomal_peptide_synthetase_SyfB BGC0000435 NRP 21.0 105.5 52.0 2.1e-06
CCA29202.1 non-ribosomal_peptide_synthetase BGC0000955 NRP + Polyketide:Modular type I 21.0 91.7 52.0 2.1e-06
ABB90279.1 non-ribosomal_peptide_synthetase BGC0001057 NRP + Polyketide 27.0 38.0 52.0 2.1e-06
AAF01762.1 AM-toxin_synthetase BGC0001261 NRP 21.0 83.2 52.0 2.1e-06
CAA79245.2 enniatin_synthetase BGC0000342 NRP 22.0 109.6 52.0 2.8e-06
CAN89663.1 putative_non-ribosomal_peptide_synthetase BGC0001070 NRP + Polyketide:Modular type I + Polyketide:Trans-AT type I 21.0 80.2 52.0 2.8e-06
CCA53799.1 iron_aquisition_yersiniabactin_synthesis_enzyme BGC0001801 NRP 22.0 79.1 52.0 2.8e-06
AID65222.1 putative_aspartate_racemase BGC0000335 NRP 21.0 100.0 51.0 3.6e-06
BAL15718.1 NRPS BGC0000432 NRP 24.0 78.0 51.0 3.6e-06
ARB50207.1 lysergyl_peptide_synthetase_21 BGC0001573 Alkaloid 25.0 60.6 51.0 3.6e-06
BAX64246.1 NRPS BGC0001623 NRP + Polyketide 22.0 77.2 51.0 3.6e-06
QBC75021.1 non-ribosomal_peptide_synthetase BGC0001968 NRP 21.0 99.4 51.0 3.6e-06
EAL88817.1 nonribosomal_peptide_synthase_GliP BGC0000361 NRP 22.0 105.3 50.0 6.1e-06
CCJ67647.1 JagC BGC0001127 NRP 21.0 97.9 50.0 6.1e-06
AJV88375.1 MfnC BGC0001214 NRP 21.0 102.8 50.0 6.1e-06
BAU50944.1 nonribosomal_peptide_synthetase BGC0001379 NRP 23.0 77.8 50.0 6.1e-06
XP_002379984.1 nonribosomal_peptide_synthase,_putative BGC0001621 NRP 25.0 87.6 50.0 6.1e-06
ADY76674.1 non-ribosomal_peptide_synthetase BGC0000950 NRP:Uridylpeptide + Other:Nucleoside 22.0 76.3 50.0 8e-06
BAN91483.1 putative_Aculeacin_A_nonribosomal_peptide_synthase BGC0001220 NRP 23.0 77.2 50.0 8e-06
CBF73453.1 nonribosomal_peptide_synthase,_putative_(JCVI) BGC0001515 NRP 21.0 81.0 50.0 8e-06