GCA_003336815.1 - 16 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

QEQU01000001.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	NRPS,transAT-PKS,T3PKS,PKS-like	9,088	115,976	bacillaene	Polyketide + NRP	100%

QEQU01000112.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 16.1	NRPS	1	7,152	plipastatin	NRP	30%

QEQU01000019.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 101.1	other	36,414	77,832	bacilysin	Other	100%
Region 101.2	sactipeptide	85,210	106,917	subtilosin A	RiPP:Thiopeptide	100%

QEQU01000022.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 123.1	sactipeptide,ranthipeptide	32,784	55,737	sporulation killing factor	RiPP:Head-to-tailcyclized peptide	100%
Region 123.2	NRPS	198,553	225,649	surfactin	NRP:Lipopeptide	47%

QEQU01000031.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 137.1	T3PKS	1	24,465

QEQU01000036.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 142.1	NRPS,NRPS-like	25,160	64,364	bacillibactin	NRP	100%

QEQU01000037.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 143.1	terpene	36,674	51,107

QEQU01000048.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 155.1	NRPS	22,518	43,884	plipastatin	NRP	30%

QEQU01000069.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 178.1	betalactone	1	14,806	fengycin	NRP	60%

QEQU01000070.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 180.1	NRPS	1	13,214	plipastatin	NRP	23%

QEQU01000074.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 184.1	lanthipeptide-class-i	1	12,405	entianin	RiPP:Lanthipeptide	90%

QEQU01000086.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 197.1	NRPS	1	10,705	surfactin	NRP:Lipopeptide	8%

QEQU01000089.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 200.1	NRPS	1	9,226	plipastatin	NRP	15%

QEQU01000099.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 211.1	NRPS	1	7,010	lichenysin	NRP	21%

No secondary metabolite regions were found in these records:: QEQU01000010.1; QEQU01000100.1; QEQU01000101.1; QEQU01000102.1; QEQU01000103.1; QEQU01000104.1; QEQU01000105.1; QEQU01000106.1; QEQU01000107.1; QEQU01000108.1; QEQU01000109.1; QEQU01000011.1; QEQU01000110.1; QEQU01000111.1; QEQU01000113.1; QEQU01000114.1; QEQU01000115.1; QEQU01000116.1; QEQU01000117.1; QEQU01000118.1; QEQU01000119.1; QEQU01000012.1; QEQU01000120.1; QEQU01000121.1; QEQU01000122.1; QEQU01000123.1; QEQU01000124.1; QEQU01000125.1; QEQU01000126.1; QEQU01000127.1; QEQU01000128.1; QEQU01000129.1; QEQU01000013.1; QEQU01000130.1; QEQU01000131.1; QEQU01000132.1; QEQU01000133.1; QEQU01000134.1; QEQU01000135.1; QEQU01000136.1; QEQU01000137.1; QEQU01000138.1; QEQU01000139.1; QEQU01000014.1; QEQU01000140.1; QEQU01000141.1; QEQU01000142.1; QEQU01000143.1; QEQU01000144.1; QEQU01000145.1; QEQU01000146.1; QEQU01000147.1; QEQU01000148.1; QEQU01000149.1; QEQU01000015.1; QEQU01000150.1; QEQU01000151.1; QEQU01000152.1; QEQU01000153.1; QEQU01000154.1; QEQU01000155.1; QEQU01000156.1; QEQU01000157.1; QEQU01000158.1; QEQU01000159.1; QEQU01000016.1; QEQU01000160.1; QEQU01000161.1; QEQU01000162.1; QEQU01000163.1; QEQU01000164.1; QEQU01000165.1; QEQU01000166.1; QEQU01000167.1; QEQU01000168.1; QEQU01000169.1; QEQU01000017.1; QEQU01000170.1; QEQU01000171.1; QEQU01000172.1; QEQU01000173.1; QEQU01000174.1; QEQU01000175.1; QEQU01000176.1; QEQU01000177.1; QEQU01000178.1; QEQU01000179.1; QEQU01000018.1; QEQU01000180.1; QEQU01000181.1; QEQU01000182.1; QEQU01000183.1; QEQU01000184.1; QEQU01000185.1; QEQU01000186.1; QEQU01000187.1; QEQU01000188.1; QEQU01000189.1; QEQU01000190.1; QEQU01000191.1; QEQU01000192.1; QEQU01000193.1; QEQU01000194.1; QEQU01000195.1; QEQU01000196.1; QEQU01000197.1; QEQU01000198.1; QEQU01000199.1; QEQU01000002.1; QEQU01000020.1; QEQU01000200.1; QEQU01000201.1; QEQU01000202.1; QEQU01000203.1; QEQU01000209.1; QEQU01000021.1; QEQU01000210.1; QEQU01000214.1; QEQU01000216.1; QEQU01000221.1; QEQU01000227.1; QEQU01000229.1; QEQU01000023.1; QEQU01000024.1; QEQU01000243.1; QEQU01000025.1; QEQU01000026.1; QEQU01000027.1; QEQU01000028.1; QEQU01000029.1; QEQU01000003.1; QEQU01000030.1; QEQU01000032.1; QEQU01000033.1; QEQU01000034.1; QEQU01000035.1; QEQU01000038.1; QEQU01000039.1; QEQU01000004.1; QEQU01000040.1; QEQU01000041.1; QEQU01000042.1; QEQU01000043.1; QEQU01000044.1; QEQU01000045.1; QEQU01000046.1; QEQU01000047.1; QEQU01000049.1; QEQU01000005.1; QEQU01000050.1; QEQU01000051.1; QEQU01000052.1; QEQU01000053.1; QEQU01000054.1; QEQU01000055.1; QEQU01000056.1; QEQU01000057.1; QEQU01000058.1; QEQU01000059.1; QEQU01000006.1; QEQU01000060.1; QEQU01000061.1; QEQU01000062.1; QEQU01000063.1; QEQU01000064.1; QEQU01000065.1; QEQU01000066.1; QEQU01000067.1; QEQU01000068.1; QEQU01000007.1; QEQU01000071.1; QEQU01000072.1; QEQU01000073.1; QEQU01000075.1; QEQU01000076.1; QEQU01000077.1; QEQU01000078.1; QEQU01000079.1; QEQU01000008.1; QEQU01000080.1; QEQU01000081.1; QEQU01000082.1; QEQU01000083.1; QEQU01000084.1; QEQU01000085.1; QEQU01000087.1; QEQU01000088.1; QEQU01000009.1; QEQU01000090.1; QEQU01000091.1; QEQU01000092.1; QEQU01000093.1; QEQU01000094.1; QEQU01000095.1; QEQU01000096.1; QEQU01000097.1; QEQU01000098.1

Compact view

QEQU01000001.1 - Region 1 - NRPS,PKS-like,T3PKS,transAT-PKS

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Location: 9,088 - 115,976 nt. (total: 106,889 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))
transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)
PKS-like: (t2pks2 or ksIII)

Legend:

core biosynthetic genes

additional biosynthetic genes

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Gene details

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 9087 - 115976:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly - ccmal - ohmal - mal) + (ccmal - mal - ohmal - mal - mal) + (ccmal - ohmal - mal - mal) + (X - ccmal - ccmal - ccmal) + (mal - mal - ccmal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 25368 - 115976:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly - ccmal - ohmal - mal) + (ccmal - mal - ohmal - mal - mal) + (ccmal - ohmal - mal - mal) + (X - ccmal - ccmal - ccmal) + (mal - mal - ccmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_29

Search NORINE for peptide: strict or relaxed

AMP-binding (498..906): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVsnmAiIYK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 60% (weak)

ctg1_32

Search NORINE for peptide: strict or relaxed

CAL_domain (63..471): pk

minowa: fatty_acid

Prediction, score:

fatty_acid: 16.8
NH2: 9.8
shikimic_acid: 0.0
Acetyl-CoA: 0.0
AHBA: 0.0

AMP-binding (1158..1553): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGMIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

ctg1_38

PKS_AT (4..288): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 66.7%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 95.0
inactive: 41.2
Methoxymalonyl-CoA: 29.1
Methylmalonyl-CoA: 22.1
Propionyl-CoA: 16.3
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg1_39

PKS_AT (7..293): pk

ATSignature: (unknown)

No matches above 50%

minowa: inactive

Prediction, score:

inactive: 30.4
Malonyl-CoA: 24.5
Isobutyryl-CoA: 8.7
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg1_40

PKS_AT (4..284): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 95.2
Methoxymalonyl-CoA: 53.7
inactive: 37.1
Methylmalonyl-CoA: 34.6
Propionyl-CoA: 22.3
Ethylmalonyl-CoA: 10.2
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Isobutyryl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

QEQU01000112.1 - Region 1 - NRPS

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Location: 1 - 7,152 nt. (total: 7,152 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

QEQU01000019.1 - Region 1 - other

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Location: 36,414 - 77,832 nt. (total: 41,419 nt) Show pHMM detection rules used

other: (LmbU or Neocarzinostat or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin or orf2_PTase)

Legend:

core biosynthetic genes

additional biosynthetic genes

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KnownClusterBlast

Similar known gene clusters

QEQU01000019.1 - Region 2 - sactipeptide

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Location: 85,210 - 106,917 nt. (total: 21,708 nt) Show pHMM detection rules used

sactipeptide: (subtilosin or thuricin or TIGR04404 or Subtilosin_A or skfc)

Legend:

core biosynthetic genes

additional biosynthetic genes

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KnownClusterBlast

Sactipeptides

Similar known gene clusters

Sactipeptide predictions

Putative Sactipeptide(s)

ctg101_110 leader / core peptide: MKKAVIVENK - GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

Sactipeptides

Core peptide predictions

ctg101_110: Putative sactipeptide; RODEO score: 33.0; Core sequence, approximate: GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

QEQU01000022.1 - Region 1 - ranthipeptide,sactipeptide

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Location: 32,784 - 55,737 nt. (total: 22,954 nt) Show pHMM detection rules used

sactipeptide: (subtilosin or thuricin or TIGR04404 or Subtilosin_A or skfc)
ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

Legend:

core biosynthetic genes

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KnownClusterBlast

Sactipeptides

Similar known gene clusters

Sactipeptide predictions

Sactipeptides - No core peptides found.

Sactipeptides

Core peptide predictions

No core peptides found.

QEQU01000022.1 - Region 2 - NRPS

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Location: 198,553 - 225,649 nt. (total: 27,097 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 198552 - 225649:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (glu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg123_244

Search NORINE for peptide: strict or relaxed

AMP-binding (466..867): glu

NRPSPredictor2: glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAKDLGVVDK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 100% (strong)

ctg123_245

Search NORINE for peptide: strict or relaxed

AMP-binding (157..585): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAFMMGMVFK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

QEQU01000031.1 - Region 1 - T3PKS

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Location: 1 - 24,465 nt. (total: 24,465 nt) Show pHMM detection rules used

Region on contig edge.

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

QEQU01000036.1 - Region 1 - NRPS,NRPS-like

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Location: 25,160 - 64,364 nt. (total: 39,205 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 25159 - 64364:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly) + (thr)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 30788 - 64364:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly) + (thr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg142_52

Search NORINE for peptide: strict or relaxed

AMP-binding (49..453): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: PLPAQGVVNK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 100% (strong)

ctg142_54

Search NORINE for peptide: strict or relaxed

AMP-binding (463..672): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DIL------K
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 40% (weak)

ctg142_55

Search NORINE for peptide: strict or relaxed

AMP-binding (1..238): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGLIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

ctg142_57

Search NORINE for peptide: strict or relaxed

AMP-binding (1..257): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

QEQU01000037.1 - Region 1 - terpene

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Location: 36,674 - 51,107 nt. (total: 14,434 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

QEQU01000048.1 - Region 1 - NRPS

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Location: 22,518 - 43,884 nt. (total: 21,367 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

QEQU01000069.1 - Region 1 - betalactone

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Location: 1 - 14,806 nt. (total: 14,806 nt) Show pHMM detection rules used

Region on contig edge.

betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

QEQU01000070.1 - Region 1 - NRPS

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Location: 1 - 13,214 nt. (total: 13,214 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 13214:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-orn) + (tyr - D-thr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg180_2

Search NORINE for peptide: strict or relaxed

AMP-binding (474..865): tyr

NRPSPredictor2: tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: tyr, bht
Single AA prediction:: tyr

Stachelhaus prediction details:

Stachelhaus sequence:: DGTITAEVAK
Nearest Stachelhaus code:: tyr
Stachelhaus code match:: 100% (strong)

AMP-binding (1505..1903): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

ctg180_3

Search NORINE for peptide: strict or relaxed

AMP-binding (134..539): orn

NRPSPredictor2: orn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: orn, lys, arg
Small clusters prediction:: orn, horn
Single AA prediction:: orn

Stachelhaus prediction details:

Stachelhaus sequence:: DVGEIGSIDK
Nearest Stachelhaus code:: orn
Stachelhaus code match:: 100% (strong)

QEQU01000074.1 - Region 1 - lanthipeptide-class-i

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Location: 1 - 12,405 nt. (total: 12,405 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-i: ((LANC_like and (Lant_dehydr_N or Lant_dehydr_C)) and not (YcaO or TIGR03882))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Lanthipeptides

KnownClusterBlast

Lanthipeptide predictions

Lanthipeptide(s) for ctg184_2 - Putative Class I

ctg184_6 leader / core peptide: MSKFDDFDLDVVKVSKQDSKITPQ - WKDhaEDhaLCDhbPGCVDhbGVLQDhbCFLQDhbIDhbCNCKIDhaK

Lanthipeptide(s) for ctg184_3 - Putative Class I

ctg184_6 leader / core peptide: MSKFDDFDLDVVKVSKQDSKITPQ - WKDhaEDhaLCDhbPGCVDhbGVLQDhbCFLQDhbIDhbCNCKIDhaK

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Similar known gene clusters

Lanthipeptides

Core peptide predictions

ctg184_6 - Class I

Cleavage pHMM score: 27.80

RODEO score: 29

Monoisotopic mass: 3346.7 Da

Molecular weight: 3349.0 Da

Number of bridges: 5

Alternative weights: (assuming N unmodified Ser/Thr residues); 3367.0 Da N = 1; 3385.0 Da N = 2; 3403.0 Da N = 3

ctg184_6 - Class I

Cleavage pHMM score: 27.80

RODEO score: 29

Monoisotopic mass: 3346.7 Da

Molecular weight: 3349.0 Da

Number of bridges: 5

Alternative weights: (assuming N unmodified Ser/Thr residues); 3367.0 Da N = 1; 3385.0 Da N = 2; 3403.0 Da N = 3

QEQU01000086.1 - Region 1 - NRPS

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Location: 1 - 10,705 nt. (total: 10,705 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 10705:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (asp) + (asp)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg197_3

Search NORINE for peptide: strict or relaxed

AMP-binding (180..347): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: ---------K
Nearest Stachelhaus code:: val
Stachelhaus code match:: 10% (weak)

ctg197_5

Search NORINE for peptide: strict or relaxed

AMP-binding (3..190): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: ---WIGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 70% (weak)

ctg197_6

Search NORINE for peptide: strict or relaxed

AMP-binding (592..995): asp

NRPSPredictor2: asp

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asp

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKVGHVGK
Nearest Stachelhaus code:: asp
Stachelhaus code match:: 100% (strong)

QEQU01000089.1 - Region 1 - NRPS

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Location: 1 - 9,226 nt. (total: 9,226 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 9226:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-val) + (pro)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg200_1

Search NORINE for peptide: strict or relaxed

AMP-binding (468..865): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFIAHVVK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 100% (strong)

AMP-binding (1499..1886): glu

NRPSPredictor2: glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: glu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWHFGSVEK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 100% (strong)

ctg200_2

Search NORINE for peptide: strict or relaxed

AMP-binding (135..528): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DVFWIGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 100% (strong)

QEQU01000099.1 - Region 1 - NRPS

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Location: 1 - 7,010 nt. (total: 7,010 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 7010:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg211_2

Search NORINE for peptide: strict or relaxed

AMP-binding (469..910): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGCVFK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)