# emapper version: emapper-2.0.1b-2-g816e190 emapper DB: 2.0 # command: ./emapper.py -i Lactobacillus_paracasei/1.contigAnn/FFN/A00000101.ffn --translate --temp_dir Lactobacillus_paracasei/4.eggNOG_mapper --output_dir Lactobacillus_paracasei/4.eggNOG_mapper --output A00000101 --cpu 36 --keep_mapping_files -m diamond # time: Mon Jun 20 13:03:09 2022 #query_name seed_eggNOG_ortholog seed_ortholog_evalue seed_ortholog_score best_tax_level Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction taxonomic scope eggNOG OGs best eggNOG OG COG Functional cat. eggNOG free text desc. FFAGCILK_00001 543734.LCABL_02620 1.4e-53 215.3 Lactobacillaceae trxC ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 1VA3Y@1239,3F7I4@33958,4HKKX@91061,COG3118@1,COG3118@2 NA|NA|NA O Belongs to the thioredoxin family FFAGCILK_00002 543734.LCABL_02630 1.1e-136 492.7 Lactobacillaceae thrE Bacteria 1TSE8@1239,3F4XE@33958,4HBW1@91061,COG2966@1,COG2966@2 NA|NA|NA S Putative threonine/serine exporter FFAGCILK_00003 543734.LCABL_02640 1.4e-75 288.9 Lactobacillaceae Bacteria 1V6P0@1239,3F63I@33958,4HJ1Y@91061,COG3610@1,COG3610@2 NA|NA|NA S Threonine/Serine exporter, ThrE FFAGCILK_00005 543734.LCABL_02650 1.7e-21 107.8 Lactobacillaceae livJ ko:K01999 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 1TPQ2@1239,3F591@33958,4H9PI@91061,COG0683@1,COG0683@2 NA|NA|NA E Receptor family ligand binding region FFAGCILK_00006 543734.LCABL_02650 7.8e-180 636.3 Lactobacillaceae livJ ko:K01999 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 1TPQ2@1239,3F591@33958,4H9PI@91061,COG0683@1,COG0683@2 NA|NA|NA E Receptor family ligand binding region FFAGCILK_00007 543734.LCABL_02660 4.3e-150 537.3 Lactobacillaceae livH ko:K01997 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 1TR24@1239,3F56V@33958,4HBFZ@91061,COG0559@1,COG0559@2 NA|NA|NA U Branched-chain amino acid transport system / permease component FFAGCILK_00008 543734.LCABL_02670 2.7e-121 441.8 Lactobacillaceae livM ko:K01995,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 1TPMZ@1239,3F44M@33958,4HBB8@91061,COG4177@1,COG4177@2 NA|NA|NA E Branched-chain amino acid transport system / permease component FFAGCILK_00009 543734.LCABL_02680 2.8e-140 504.6 Lactobacillaceae livG ko:K01995,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 1TR0P@1239,3F4IH@33958,4HASG@91061,COG0411@1,COG0411@2 NA|NA|NA E Branched-chain amino acid ATP-binding cassette transporter FFAGCILK_00010 543734.LCABL_02690 5.1e-125 453.8 Lactobacillaceae livF ko:K01996 ko02010,ko02024,map02010,map02024 M00237 ko00000,ko00001,ko00002,ko02000 3.A.1.4 Bacteria 1TPW4@1239,3F3RP@33958,4HABJ@91061,COG0410@1,COG0410@2 NA|NA|NA E ABC transporter FFAGCILK_00011 543734.LCABL_02700 3.1e-167 594.3 Lactobacillaceae Bacteria 1V8NG@1239,3F41V@33958,4HJ22@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha/beta hydrolase of unknown function (DUF915) FFAGCILK_00012 543734.LCABL_02710 1.9e-234 818.1 Lactobacillaceae celB GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016310,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0071704 2.7.1.207 ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 M00275,M00281 R04393,R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.1,4.A.3.2 Bacteria 1TP8D@1239,3FC6Y@33958,4HE28@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane FFAGCILK_00013 543734.LCABL_02720 7.6e-118 429.9 Lactobacillaceae XK27_12570 5.1.3.9 ko:K01788 ko00520,map00520 R02087 RC00290 ko00000,ko00001,ko01000 Bacteria 1VTI6@1239,3F3YB@33958,4HV5Q@91061,COG3010@1,COG3010@2 NA|NA|NA G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) FFAGCILK_00014 543734.LCABL_02740 6.2e-117 426.8 Lactobacillaceae deoC GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4,5.4.2.8 ko:K01619,ko:K01840 ko00030,ko00051,ko00520,ko01100,ko01110,ko01130,map00030,map00051,map00520,map01100,map01110,map01130 M00114 R01066,R01818 RC00408,RC00436,RC00437 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPAJ@1239,3F4M3@33958,4HAAJ@91061,COG0274@1,COG0274@2 NA|NA|NA F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate FFAGCILK_00015 543734.LCABL_02750 6.8e-231 806.2 Lactobacillaceae deoB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008973,GO:0016853,GO:0016866,GO:0016868,GO:0044424,GO:0044444,GO:0044464 5.4.2.7 ko:K01839 ko00030,ko00230,map00030,map00230 R01057,R02749 RC00408 ko00000,ko00001,ko01000 Bacteria 1TP70@1239,3F3Y4@33958,4H9RU@91061,COG1015@1,COG1015@2 NA|NA|NA G Phosphotransfer between the C1 and C5 carbon atoms of pentose FFAGCILK_00016 543734.LCABL_02760 3.4e-129 467.6 Lactobacillaceae deoD GO:0003674,GO:0003824,GO:0004731,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006152,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009164,GO:0009987,GO:0015949,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0019686,GO:0033554,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 2.4.2.1,2.4.2.28 ko:K00772,ko:K03784 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 M00034 R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122,RC02819 ko00000,ko00001,ko00002,ko01000 iAPECO1_1312.APECO1_1997,iB21_1397.B21_04226,iE2348C_1286.E2348C_4682,iEC042_1314.EC042_4881,iECABU_c1320.ECABU_c50190,iECBD_1354.ECBD_3636,iECB_1328.ECB_04260,iECD_1391.ECD_04260,iECED1_1282.ECED1_5255,iECIAI39_1322.ECIAI39_4916,iECNA114_1301.ECNA114_4626,iECO26_1355.ECO26_5590,iECOK1_1307.ECOK1_4950,iECP_1309.ECP_4768,iEcolC_1368.EcolC_3672,iLF82_1304.LF82_0467,iNRG857_1313.NRG857_22170,iPC815.YPO0440,iSFV_1184.SFV_4418,iSF_1195.SF4416,iSFxv_1172.SFxv_4809,iS_1188.S4687,iUMN146_1321.UM146_22680,iUMNK88_1353.UMNK88_5303,iUTI89_1310.UTI89_C5155,ic_1306.c5468 Bacteria 1TQPG@1239,3F4K1@33958,4HADM@91061,COG0813@1,COG0813@2 NA|NA|NA F Purine nucleoside phosphorylase FFAGCILK_00017 543734.LCABL_02770 2.4e-153 548.9 Lactobacillaceae ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1VG0Z@1239,3F50V@33958,4HBE9@91061,COG0791@1,COG0791@2 NA|NA|NA M NlpC P60 family protein FFAGCILK_00020 543734.LCABL_02800 3.3e-258 897.1 Lactobacillaceae nox 1.6.3.4 ko:K17869 ko00000,ko01000 Bacteria 1TPWW@1239,3F449@33958,4H9U7@91061,COG0446@1,COG0446@2 NA|NA|NA C NADH oxidase FFAGCILK_00021 543734.LCABL_02810 4.6e-141 507.3 Lactobacillaceae sepS16B Bacteria 1US2T@1239,28MN3@1,2ZAXQ@2,3F55K@33958,4HW4H@91061 NA|NA|NA FFAGCILK_00022 543734.LCABL_02820 1.2e-118 432.6 Lactobacillaceae Bacteria 1VJZJ@1239,2EEPZ@1,338HP@2,3F55G@33958,4HR6K@91061 NA|NA|NA FFAGCILK_00023 543734.LCABL_02830 0.0 1527.7 Lactobacillaceae dinG 3.1.12.1,3.6.4.12 ko:K07464,ko:K10844 ko03022,ko03420,map03022,map03420 M00290 ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400 Bacteria 1TPNB@1239,3F473@33958,4HD6T@91061,COG1199@1,COG1199@2 NA|NA|NA KL DEAD_2 FFAGCILK_00024 543734.LCABL_02840 5.1e-240 836.6 Lactobacillaceae ko:K02027,ko:K05813 ko02010,map02010 M00198,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3 Bacteria 1TSBD@1239,3F5HX@33958,4IQ65@91061,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein FFAGCILK_00025 543734.LCABL_02850 8.6e-85 320.1 Lactobacillaceae Bacteria 1UFZH@1239,29V33@1,30GGE@2,3F5BQ@33958,4IF1H@91061 NA|NA|NA FFAGCILK_00026 543734.LCABL_02860 0.0 1092.4 Bacilli strH 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 GH20 Bacteria 1TT9S@1239,4HEM6@91061,COG3525@1,COG3525@2 NA|NA|NA G Gram-positive signal peptide protein, YSIRK family FFAGCILK_00027 543734.LCABL_02870 3.3e-194 684.1 Lactobacillaceae manA 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 Bacteria 1VRGI@1239,3F40I@33958,4HBFW@91061,COG1482@1,COG1482@2 NA|NA|NA G mannose-6-phosphate isomerase FFAGCILK_00028 543734.LCABL_02880 1.2e-129 469.2 Lactobacillaceae XK27_08435 ko:K03710 ko00000,ko03000 Bacteria 1UYYY@1239,3F5F4@33958,4HGI6@91061,COG2188@1,COG2188@2 NA|NA|NA K UTRA FFAGCILK_00029 543734.LCABL_02890 1.6e-219 768.5 Lactobacillaceae agaS GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034219,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 ko:K02082 ko00000,ko01000 Bacteria 1TQUT@1239,3F3YS@33958,4HDKQ@91061,COG2222@1,COG2222@2 NA|NA|NA G SIS domain FFAGCILK_00030 543734.LCABL_02900 2.9e-226 790.8 Lactobacillaceae nagA 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 R02059 RC00166,RC00300 ko00000,ko00001,ko01000 Bacteria 1TPFK@1239,3F40F@33958,4HC6C@91061,COG1820@1,COG1820@2 NA|NA|NA G Belongs to the metallo-dependent hydrolases superfamily. NagA family FFAGCILK_00031 543734.LCABL_02910 0.0 1248.8 Lactobacillaceae bgaC 3.2.1.23 ko:K01190,ko:K12308 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 Bacteria 1TSHK@1239,3F5XU@33958,4HBAR@91061,COG1874@1,COG1874@2 NA|NA|NA G Glycosyl hydrolases family 35 FFAGCILK_00032 543734.LCABL_02920 4.7e-82 310.5 Lactobacillaceae manX_1 2.7.1.191 ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 Bacteria 1V46G@1239,3FC7S@33958,4HHPN@91061,COG3444@1,COG3444@2 NA|NA|NA G PTS system sorbose subfamily IIB component FFAGCILK_00033 543734.LCABL_02930 4.4e-161 573.9 Lactobacillaceae XK27_08455 ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 Bacteria 1TSX0@1239,3F4X4@33958,4HBRB@91061,COG3715@1,COG3715@2 NA|NA|NA G PTS system sorbose-specific iic component FFAGCILK_00034 543734.LCABL_02940 7.9e-146 523.1 Lactobacillaceae manZ_1 ko:K02747,ko:K02796,ko:K02815,ko:K17467 ko00030,ko00051,ko00052,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00052,map00520,map01100,map01120,map02060 M00276,M00277,M00278,M00610 R02630,R04076,R08366,R10407 RC00017,RC01069,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.17,4.A.6.1.3,4.A.6.1.4 Bacteria 1UMKU@1239,3F434@33958,4HC75@91061,COG3716@1,COG3716@2 NA|NA|NA G PTS system mannose/fructose/sorbose family IID component FFAGCILK_00035 543734.LCABL_02950 9.2e-65 252.7 Lactobacillaceae XK27_08465 2.7.1.191 ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 Bacteria 1VB8U@1239,3F7YU@33958,4HKV5@91061,COG2893@1,COG2893@2 NA|NA|NA G PTS system fructose IIA component FFAGCILK_00036 543734.LCABL_02960 6.9e-218 763.1 Lactobacillaceae Bacteria 1VJ1K@1239,2E865@1,332JJ@2,3F662@33958,4IFBU@91061 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2325) FFAGCILK_00037 1423816.BACQ01000062_gene2361 6.3e-192 676.8 Lactobacillaceae 4.4.1.8 ko:K00842,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 Bacteria 1TP5G@1239,3F4JX@33958,4H9PE@91061,COG1168@1,COG1168@2 NA|NA|NA E Aminotransferase, class I FFAGCILK_00038 543734.LCABL_03000 2.6e-197 694.5 Lactobacillaceae pepP 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 ko00000,ko01000,ko01002 Bacteria 1TQ44@1239,3F9GC@33958,4HV4S@91061,COG0006@1,COG0006@2 NA|NA|NA E Creatinase/Prolidase N-terminal domain FFAGCILK_00039 543734.LCABL_03010 2.3e-251 874.4 Lactobacillaceae GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016310,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0071704 2.7.1.207 ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 M00275,M00281 R04393,R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.1,4.A.3.2 Bacteria 1TP8D@1239,3F744@33958,4HEGS@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane FFAGCILK_00040 543734.LCABL_03020 2.3e-59 234.6 Lactobacillaceae 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 Bacteria 1V6UA@1239,3F8G8@33958,4HK0J@91061,COG1440@1,COG1440@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit FFAGCILK_00041 543734.LCABL_03030 3e-51 207.6 Lactobacillaceae 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 Bacteria 1VCDD@1239,3F7P9@33958,4HZCJ@91061,COG1447@1,COG1447@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIA subunit FFAGCILK_00042 543734.LCABL_03040 1.6e-188 665.2 Lactobacillaceae ypdE GO:0003674,GO:0003824,GO:0004177,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 Bacteria 1TNZT@1239,3F55I@33958,4H9SM@91061,COG1363@1,COG1363@2 NA|NA|NA E M42 glutamyl aminopeptidase FFAGCILK_00043 543734.LCABL_03050 0.0 1160.2 Lactobacillaceae licR 2.7.1.194,2.7.1.200,2.7.1.202,2.7.1.204 ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 M00273,M00279,M00283,M00306,M00550,M00807 R03232,R05570,R07671,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1,4.A.5,4.A.5.1,4.A.7.1 Bacteria 1TS2U@1239,3F6RZ@33958,4HTK5@91061,COG1762@1,COG1762@2,COG3711@1,COG3711@2 NA|NA|NA GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 FFAGCILK_00044 543734.LCABL_03060 3.6e-243 847.0 Lactobacillaceae 3.4.11.4 ko:K01258 ko00000,ko01000,ko01002 Bacteria 1TP3A@1239,3F45V@33958,4HAZE@91061,COG2195@1,COG2195@2 NA|NA|NA E Cleaves the N-terminal amino acid of tripeptides FFAGCILK_00045 543734.LCABL_03070 8.6e-293 1012.3 Lactobacillaceae ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TNYQ@1239,3F3JE@33958,4HAMK@91061,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter, substratebinding protein FFAGCILK_00046 543734.LCABL_03080 3.2e-110 404.4 Lactobacillaceae ko:K06889 ko00000 Bacteria 1V3PW@1239,3F7G3@33958,4HGZK@91061,COG3153@1,COG3153@2 NA|NA|NA S Acetyltransferase (GNAT) family FFAGCILK_00047 1158610.UC3_01561 1.5e-99 369.0 Enterococcaceae fucA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019324,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 4.1.2.17 ko:K01628 ko00051,ko01120,map00051,map01120 R02262 RC00603,RC00604 ko00000,ko00001,ko01000 Bacteria 1TPDV@1239,4AZV7@81852,4HDTK@91061,COG0235@1,COG0235@2 NA|NA|NA G Class II Aldolase and Adducin N-terminal domain FFAGCILK_00048 1158607.UAU_04216 3.9e-39 167.9 Enterococcaceae 2.7.1.200,2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02773 ko00051,ko00052,ko01100,ko01120,ko02060,map00051,map00052,map01100,map01120,map02060 M00273,M00279 R03232,R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.5.1 Bacteria 1TVMW@1239,4B58D@81852,4I3MS@91061,COG1762@1,COG1762@2 NA|NA|NA G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 FFAGCILK_00049 1158607.UAU_04215 9.3e-36 156.0 Enterococcaceae 2.7.1.200 ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1 Bacteria 1VHRV@1239,4B3XK@81852,4IBSY@91061,COG3414@1,COG3414@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit FFAGCILK_00050 1158607.UAU_04214 2e-204 718.4 Enterococcaceae ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.5.1 Bacteria 1TQ10@1239,4B0Z8@81852,4HF7Z@91061,COG3775@1,COG3775@2 NA|NA|NA G PTS system sugar-specific permease component FFAGCILK_00051 1158607.UAU_04213 1.2e-143 516.2 Enterococcaceae 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1V410@1239,4B1RF@81852,4I8YT@91061,COG0111@1,COG0111@2 NA|NA|NA EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain FFAGCILK_00052 1158607.UAU_04212 1.3e-197 696.4 Enterococcaceae 2.7.1.194,2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02821 ko00051,ko00053,ko01100,ko01120,ko02060,map00051,map00053,map01100,map01120,map02060 M00273,M00283,M00550 R03232,R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.7.1 Bacteria 1TQT1@1239,4B004@81852,4H9N4@91061,COG1762@1,COG1762@2,COG3711@1,COG3711@2 NA|NA|NA GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 FFAGCILK_00053 543734.LCABL_03100 7e-93 346.7 Lactobacillaceae ko:K16925 M00582 ko00000,ko00002,ko02000 3.A.1.30 Bacteria 1V2G5@1239,3FBNZ@33958,4IRFG@91061,COG4721@1,COG4721@2 NA|NA|NA S ABC-type cobalt transport system, permease component FFAGCILK_00054 543734.LCABL_03110 5.8e-239 833.2 Lactobacillaceae ko:K02006,ko:K16784,ko:K16786,ko:K16787,ko:K16927 ko02010,map02010 M00245,M00246,M00581,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TPH8@1239,3FBS0@33958,4HAJM@91061,COG1122@1,COG1122@2 NA|NA|NA P ABC transporter FFAGCILK_00055 543734.LCABL_03120 4.5e-104 384.0 Lactobacillaceae ko:K16785 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TUDZ@1239,3F4FG@33958,4HCPC@91061,COG0619@1,COG0619@2 NA|NA|NA P cobalt transport FFAGCILK_00056 543734.LCABL_03130 2.2e-128 464.9 Lactobacillaceae tenA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.2 ko:K03707 ko00730,ko01100,map00730,map01100 R02133,R09993 RC00224,RC00652,RC02832 ko00000,ko00001,ko01000,ko03000 Bacteria 1TPK0@1239,3FB7U@33958,4HCPF@91061,COG0819@1,COG0819@2 NA|NA|NA K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway FFAGCILK_00057 543734.LCABL_03140 7.6e-83 313.2 Lactobacillaceae thiW ko:K16786,ko:K16787 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1V6HH@1239,3F6M6@33958,4HHG6@91061,COG4732@1,COG4732@2 NA|NA|NA S Thiamine-precursor transporter protein (ThiW) FFAGCILK_00058 543734.LCABL_03150 3.2e-150 537.7 Lactobacillaceae thiM 2.7.1.50 ko:K00878 ko00730,ko01100,map00730,map01100 M00127 R04448 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V1R6@1239,3F43J@33958,4HFTJ@91061,COG2145@1,COG2145@2 NA|NA|NA H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) FFAGCILK_00059 543734.LCABL_03160 6.2e-106 390.2 Lactobacillaceae thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3ZR@1239,3FB7Y@33958,4HH1E@91061,COG0352@1,COG0352@2 NA|NA|NA H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) FFAGCILK_00060 543734.LCABL_03170 6.1e-146 523.5 Lactobacillaceae thiD GO:0008150,GO:0040007 2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17 ko:K00941,ko:K03147,ko:K21219 ko00730,ko01100,map00730,map01100 M00127 R03223,R03471,R03472,R04509,R10712 RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ4A@1239,3F3NA@33958,4HAAH@91061,COG0351@1,COG0351@2 NA|NA|NA H Phosphomethylpyrimidine kinase FFAGCILK_00061 543734.LCABL_03180 5.6e-272 943.0 Lactobacillaceae ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 1UYSD@1239,3F48U@33958,4IPMN@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease FFAGCILK_00062 543734.LCABL_03200 7.4e-31 139.4 Lactobacillaceae Bacteria 1U879@1239,2AIT2@1,3199Z@2,3FAMW@33958,4II4Z@91061 NA|NA|NA FFAGCILK_00063 543734.LCABL_03210 3.5e-188 664.1 Lactobacillaceae rbsR ko:K02529 ko00000,ko03000 Bacteria 1TQ7K@1239,3F44Q@33958,4HE07@91061,COG1609@1,COG1609@2 NA|NA|NA K Periplasmic binding proteins and sugar binding domain of LacI family FFAGCILK_00064 543734.LCABL_03220 8.6e-66 256.1 Lactobacillaceae rbsD GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009056,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016052,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0016887,GO:0017111,GO:0019303,GO:0019321,GO:0019323,GO:0022804,GO:0022857,GO:0034219,GO:0042623,GO:0042626,GO:0042802,GO:0043211,GO:0043492,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:1901575 5.4.99.62 ko:K06726 ko02010,map02010 R08247 RC02247 ko00000,ko00001,ko01000 iAF1260.b3748,iBWG_1329.BWG_3439,iECDH10B_1368.ECDH10B_3936,iECDH1ME8569_1439.ECDH1ME8569_3636,iECH74115_1262.ECH74115_5184,iECSP_1301.ECSP_4798,iECs_1301.ECs4690,iETEC_1333.ETEC_4039,iEcDH1_1363.EcDH1_4219,iJO1366.b3748,iJR904.b3748,iY75_1357.Y75_RS18330 Bacteria 1VA2V@1239,3F6GA@33958,4HIFW@91061,COG1869@1,COG1869@2 NA|NA|NA G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose FFAGCILK_00065 543734.LCABL_03230 2e-283 981.1 Lactobacillaceae rbsA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0031224,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034219,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043190,GO:0043211,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0097159,GO:0097367,GO:0098533,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.17 ko:K10441,ko:K10542 ko02010,map02010 M00212,M00214 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.3 iEC55989_1330.EC55989_4224,iECSE_1348.ECSE_4039,iECW_1372.ECW_m4052,iEcE24377_1341.EcE24377A_4265,iWFL_1372.ECW_m4052,iYL1228.KPN_04154 Bacteria 1TP6I@1239,3FBUB@33958,4H9VK@91061,COG1129@1,COG1129@2 NA|NA|NA G ABC transporter FFAGCILK_00066 543734.LCABL_03240 6.1e-145 520.4 Lactobacillaceae rbsC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015591,GO:0015749,GO:0015750,GO:0015752,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034219,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 ko:K03549,ko:K10440 ko02010,map02010 M00212 ko00000,ko00001,ko00002,ko02000 2.A.72,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 iAF1260.b3750,iAPECO1_1312.APECO1_2713,iB21_1397.B21_03581,iBWG_1329.BWG_3441,iE2348C_1286.E2348C_4060,iEC042_1314.EC042_4137,iEC55989_1330.EC55989_4225,iECABU_c1320.ECABU_c42350,iECBD_1354.ECBD_4280,iECB_1328.ECB_03636,iECDH10B_1368.ECDH10B_3938,iECDH1ME8569_1439.ECDH1ME8569_3638,iECED1_1282.ECED1_4440,iECH74115_1262.ECH74115_5186,iECIAI1_1343.ECIAI1_3934,iECNA114_1301.ECNA114_3899,iECO103_1326.ECO103_4407,iECO111_1330.ECO111_4584,iECO26_1355.ECO26_4828,iECOK1_1307.ECOK1_4199,iECS88_1305.ECS88_4172,iECSE_1348.ECSE_4040,iECSF_1327.ECSF_3598,iECSP_1301.ECSP_4800,iECUMN_1333.ECUMN_4280,iECs_1301.ECs4692,iEcDH1_1363.EcDH1_4217,iEcE24377_1341.EcE24377A_4266,iEcHS_1320.EcHS_A3966,iEcSMS35_1347.EcSMS35_4118,iEcolC_1368.EcolC_4244,iJO1366.b3750,iJR904.b3750,iLF82_1304.LF82_1817,iNRG857_1313.NRG857_18675,iUMN146_1321.UM146_18940,iUMNK88_1353.UMNK88_4562,iUTI89_1310.UTI89_C4305,iY75_1357.Y75_RS18320,ic_1306.c4678 Bacteria 1TP72@1239,3F5NF@33958,4H9Y3@91061,COG1172@1,COG1172@2 NA|NA|NA U Belongs to the binding-protein-dependent transport system permease family FFAGCILK_00067 543734.LCABL_03250 9.5e-167 592.8 Lactobacillaceae rbsB GO:0003674,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006935,GO:0008150,GO:0008643,GO:0009605,GO:0015144,GO:0015145,GO:0015749,GO:0015750,GO:0015752,GO:0016020,GO:0016021,GO:0022857,GO:0030246,GO:0030288,GO:0030313,GO:0031224,GO:0031975,GO:0034219,GO:0036094,GO:0040011,GO:0042221,GO:0042330,GO:0042597,GO:0044425,GO:0044464,GO:0048029,GO:0050896,GO:0050918,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 ko:K10439 ko02010,ko02030,map02010,map02030 M00212 ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 Bacteria 1TQ1B@1239,3FCEY@33958,4HCSN@91061,COG1879@1,COG1879@2 NA|NA|NA G Periplasmic binding protein domain FFAGCILK_00068 543734.LCABL_03260 3.1e-162 577.8 Lactobacillaceae rbsK 2.7.1.15 ko:K00852 ko00030,map00030 R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TQRC@1239,3FB6B@33958,4HE6Z@91061,COG0524@1,COG0524@2 NA|NA|NA H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway FFAGCILK_00069 543734.LCABL_03280 0.0 1281.5 Lactobacillaceae pbpC ko:K18149,ko:K21467 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01011 Bacteria 1TPER@1239,3F5K3@33958,4IQSR@91061,COG0768@1,COG0768@2 NA|NA|NA M NTF2-like N-terminal transpeptidase domain FFAGCILK_00070 543734.LCABL_03290 5.4e-240 836.6 Lactobacillaceae ydiC1 Bacteria 1TPRN@1239,3F4D4@33958,4HBXJ@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily FFAGCILK_00071 543734.LCABL_03300 4e-72 277.3 Lactobacillaceae Bacteria 1V939@1239,3F7MR@33958,4HJRC@91061,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein FFAGCILK_00072 543734.LCABL_03310 9.7e-103 379.4 Lactobacillaceae Bacteria 1VXXQ@1239,2DEN3@1,32U3P@2,3F73U@33958,4HXNG@91061 NA|NA|NA FFAGCILK_00073 543734.LCABL_03320 2.6e-24 117.5 Lactobacillaceae Bacteria 1U735@1239,2ATAB@1,31ITC@2,3F8WX@33958,4IGXP@91061 NA|NA|NA FFAGCILK_00074 543734.LCABL_03330 2.2e-64 252.3 Lactobacillaceae Bacteria 1U8FC@1239,29QQ0@1,30BPR@2,3FAX8@33958,4IID8@91061 NA|NA|NA FFAGCILK_00075 543734.LCABL_03340 1.5e-52 213.0 Lactobacillaceae Bacteria 1U8FC@1239,29QQ0@1,30BPR@2,3FAX8@33958,4IID8@91061 NA|NA|NA FFAGCILK_00076 543734.LCABL_03440 5.2e-268 929.9 Lactobacillaceae frdC 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPAR@1239,3FBRV@33958,4ISAE@91061,COG1053@1,COG1053@2 NA|NA|NA C HI0933-like protein FFAGCILK_00077 543734.LCABL_03450 1.2e-198 699.9 Lactobacillaceae Bacteria 1TQT1@1239,3F64K@33958,4H9N4@91061,COG3711@1,COG3711@2 NA|NA|NA GKT transcriptional antiterminator FFAGCILK_00078 543734.LCABL_03470 1.5e-49 201.8 Lactobacillaceae ptxB 2.7.1.194,2.7.1.200,2.7.1.204 ko:K02774,ko:K02822,ko:K20113 ko00052,ko00053,ko01100,ko01120,ko02060,map00052,map00053,map01100,map01120,map02060 M00279,M00283,M00550,M00807 R05570,R07671,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5,4.A.5.1,4.A.7.1 Bacteria 1VBHM@1239,3F96C@33958,4HM7H@91061,COG3414@1,COG3414@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit FFAGCILK_00079 543734.LCABL_03480 2.7e-209 734.6 Lactobacillaceae ulaA 2.7.1.194 ko:K02822,ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 Bacteria 1TQK5@1239,3F4Y4@33958,4HBAD@91061,COG3037@1,COG3037@2 NA|NA|NA S PTS system sugar-specific permease component FFAGCILK_00080 543734.LCABL_03490 7.1e-66 256.5 Lactobacillaceae Bacteria 1VIC6@1239,2DQQD@1,32UPI@2,3F8E7@33958,4HSMN@91061 NA|NA|NA FFAGCILK_00081 543734.LCABL_03500 1.8e-161 575.1 Lactobacillaceae 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ01@1239,3F611@33958,4HA99@91061,COG0191@1,COG0191@2 NA|NA|NA G Fructose-bisphosphate aldolase class-II FFAGCILK_00082 543734.LCABL_03510 7.4e-115 419.9 Lactobacillaceae 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 Bacteria 1V4KB@1239,3F7CA@33958,4HI0A@91061,COG0645@1,COG0645@2 NA|NA|NA S Zeta toxin FFAGCILK_00083 543734.LCABL_03520 4.5e-157 560.5 Lactobacillaceae Bacteria 1TTRR@1239,3F9RY@33958,4IHFC@91061,COG1378@1,COG1378@2 NA|NA|NA K Sugar-specific transcriptional regulator TrmB FFAGCILK_00084 543734.LCABL_03530 4.8e-22 110.2 Lactobacillaceae ko:K07090 ko00000 Bacteria 1TQ8H@1239,3F7J9@33958,4IIWZ@91061,COG0730@1,COG0730@2 NA|NA|NA S Sulfite exporter TauE/SafE FFAGCILK_00085 543734.LCABL_03530 3.2e-96 357.8 Lactobacillaceae ko:K07090 ko00000 Bacteria 1TQ8H@1239,3F7J9@33958,4IIWZ@91061,COG0730@1,COG0730@2 NA|NA|NA S Sulfite exporter TauE/SafE FFAGCILK_00086 543734.LCABL_03540 2.5e-178 631.3 Lactobacillaceae rapL 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 R00671 RC00354 ko00000,ko00001,ko01000 Bacteria 1TPHM@1239,3F5HH@33958,4HBWI@91061,COG2423@1,COG2423@2 NA|NA|NA E Ornithine cyclodeaminase/mu-crystallin family FFAGCILK_00087 543734.LCABL_03550 1.5e-149 535.4 Bacilli 3.1.1.24 ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991 RC00825 ko00000,ko00001,ko00002,ko01000 Bacteria 1UKJS@1239,4ITJ3@91061,COG0596@1,COG0596@2 NA|NA|NA S Alpha/beta hydrolase family FFAGCILK_00091 543734.LCABL_03600 1e-229 803.1 Lactobacillaceae Bacteria 1TT3P@1239,3F4YY@33958,4I28K@91061,COG3209@1,COG3209@2 NA|NA|NA M Bacterial Ig-like domain (group 3) FFAGCILK_00093 543734.LCABL_03610 1.7e-69 268.5 Lactobacillaceae pdxH ko:K07006 ko00000 Bacteria 1VW4G@1239,3F6IW@33958,4HW37@91061,COG3576@1,COG3576@2 NA|NA|NA S Pyridoxamine 5'-phosphate oxidase FFAGCILK_00094 1291743.LOSG293_590030 1.1e-70 272.3 Lactobacillaceae yqeB Bacteria 1V717@1239,2AK1X@1,31ARI@2,3F6WW@33958,4HIQ9@91061 NA|NA|NA S Pyrimidine dimer DNA glycosylase FFAGCILK_00095 543734.LCABL_03660 1.3e-151 542.3 Bacilli 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1UYZ3@1239,4HFV8@91061,COG2367@1,COG2367@2 NA|NA|NA V Beta-lactamase FFAGCILK_00096 1545701.LACWKB10_1866 3.2e-284 984.2 Lactobacillaceae ptsG 2.7.1.199 ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 M00809 R02738 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.13,4.A.1.1.14,4.A.1.1.9 Bacteria 1TPJ8@1239,3F44V@33958,4HA8X@91061,COG1263@1,COG1263@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system, EIIB FFAGCILK_00098 543734.LCABL_04530 1.8e-187 661.8 Lactobacillaceae odh 1.5.1.28 ko:K04940 ko00000,ko01000 Bacteria 1TUSI@1239,3F5C0@33958,4HDHM@91061,COG0240@1,COG0240@2 NA|NA|NA C NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain FFAGCILK_00099 543734.LCABL_04540 5.9e-132 476.9 Lactobacillaceae ko:K16960 ko02010,map02010 M00585 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.13 Bacteria 1TNYD@1239,3F5KX@33958,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter FFAGCILK_00100 543734.LCABL_04550 6e-160 570.1 Lactobacillaceae ko:K02424,ko:K16957 ko02010,map02010 M00234,M00585 ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3.10,3.A.1.3.13,3.A.1.3.14 Bacteria 1UX4B@1239,3F613@33958,4HG72@91061,COG0834@1,COG0834@2 NA|NA|NA ET Bacterial periplasmic substrate-binding proteins FFAGCILK_00101 543734.LCABL_04560 6.5e-114 416.8 Lactobacillaceae ko:K16958,ko:K16959,ko:K16962 ko02010,map02010 M00585,M00586 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.13 Bacteria 1TY31@1239,3F64V@33958,4HBN2@91061,COG0765@1,COG0765@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component FFAGCILK_00102 543734.LCABL_04570 4.6e-115 420.6 Lactobacillaceae ko:K16958,ko:K16959,ko:K16962 ko02010,map02010 M00585,M00586 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.13 Bacteria 1V4MI@1239,3F7Q4@33958,4IQKS@91061,COG0765@1,COG0765@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component FFAGCILK_00103 543734.LCABL_04580 4.7e-238 830.1 Lactobacillaceae kgtP ko:K03761 ko00000,ko02000 2.A.1.6.2 Bacteria 1TQIJ@1239,3F3N4@33958,4HAM0@91061,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter FFAGCILK_00105 568703.LGG_00485 2.4e-11 73.9 Lactobacillaceae Bacteria 1U8F6@1239,29QPW@1,30BPK@2,3FAX1@33958,4IID2@91061 NA|NA|NA S YvrJ protein family FFAGCILK_00106 543734.LCABL_04610 6.4e-142 510.0 Lactobacillaceae 3.2.1.17 ko:K01185,ko:K07273 ko00000,ko01000 Bacteria 1V3SH@1239,3F6ZF@33958,4HNR1@91061,COG3757@1,COG3757@2 NA|NA|NA M hydrolase, family 25 FFAGCILK_00107 543734.LCABL_04620 1.3e-131 475.7 Lactobacillaceae VY92_08700 Bacteria 1TRHF@1239,3F3VA@33958,4HBXH@91061,COG4221@1,COG4221@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family FFAGCILK_00108 543734.LCABL_04630 3.6e-114 417.5 Bacilli Bacteria 1V465@1239,4HN5X@91061,COG0716@1,COG0716@2 NA|NA|NA C Flavodoxin FFAGCILK_00109 543734.LCABL_04640 8.7e-87 326.2 Lactobacillaceae ygfC Bacteria 1V4D3@1239,3F6ZM@33958,4HJ8Z@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family FFAGCILK_00110 543734.LCABL_04650 1.7e-185 655.2 Lactobacillaceae hrtB ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TWFZ@1239,3F3K5@33958,4H9RQ@91061,COG0577@1,COG0577@2 NA|NA|NA V ABC transporter permease FFAGCILK_00111 543734.LCABL_04660 1.4e-119 435.6 Lactobacillaceae devA 3.6.3.25 ko:K02003,ko:K06020,ko:K09810 ko02010,map02010 M00255,M00258 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.125 Bacteria 1TQP5@1239,3F4RP@33958,4HBXK@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein FFAGCILK_00112 543734.LCABL_04670 1.2e-39 168.7 Lactobacillaceae Bacteria 1VMY1@1239,3F814@33958,4HRA4@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins FFAGCILK_00113 543734.LCABL_04680 3.4e-64 250.8 Lactobacillaceae Bacteria 1VHME@1239,3F7IG@33958,4IRT3@91061,COG4679@1,COG4679@2 NA|NA|NA S Phage derived protein Gp49-like (DUF891) FFAGCILK_00114 543734.LCABL_04690 1e-262 912.1 Lactobacillaceae npr 1.11.1.1 ko:K05910 ko00000,ko01000 Bacteria 1TPWW@1239,3F449@33958,4H9U7@91061,COG0446@1,COG0446@2 NA|NA|NA C NADH oxidase FFAGCILK_00115 543734.LCABL_04700 1.7e-151 542.0 Lactobacillaceae Bacteria 1TR16@1239,3F55S@33958,4HCZ6@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase FFAGCILK_00116 543734.LCABL_04710 1.9e-43 181.4 Lactobacillaceae ko:K19157 ko00000,ko01000,ko02048 Bacteria 1U69Z@1239,3F7EP@33958,4IG17@91061,COG3041@1,COG3041@2 NA|NA|NA S Bacterial toxin of type II toxin-antitoxin system, YafQ FFAGCILK_00117 543734.LCABL_04720 1.6e-185 655.2 Lactobacillaceae cytR 5.1.1.1 ko:K01775,ko:K02529,ko:K05499 ko00473,ko01100,ko01502,map00473,map01100,map01502 R00401 RC00285 ko00000,ko00001,ko01000,ko01011,ko03000 Bacteria 1TRHK@1239,3F5FI@33958,4HB9P@91061,COG1609@1,COG1609@2 NA|NA|NA K Periplasmic binding proteins and sugar binding domain of LacI family FFAGCILK_00118 543734.LCABL_04730 3e-84 317.8 Lactobacillaceae 2.7.1.191 ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 Bacteria 1V8BP@1239,3F6R3@33958,4HWNX@91061,COG3444@1,COG3444@2 NA|NA|NA G PTS system sorbose subfamily IIB component FFAGCILK_00119 543734.LCABL_04740 2.8e-127 461.5 Lactobacillaceae ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 Bacteria 1TSX0@1239,3F4X4@33958,4HBRB@91061,COG3715@1,COG3715@2 NA|NA|NA G PTS system sorbose-specific iic component FFAGCILK_00120 543734.LCABL_04750 1.4e-153 548.9 Lactobacillaceae ko:K02747,ko:K02796,ko:K02815,ko:K17467 ko00030,ko00051,ko00052,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00052,map00520,map01100,map01120,map02060 M00276,M00277,M00278,M00610 R02630,R04076,R08366,R10407 RC00017,RC01069,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.17,4.A.6.1.3,4.A.6.1.4 Bacteria 1TSXA@1239,3FBHP@33958,4IQM2@91061,COG3716@1,COG3716@2 NA|NA|NA G PTS system mannose/fructose/sorbose family IID component FFAGCILK_00121 543734.LCABL_04760 0.0 1539.6 Lactobacillaceae 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 GH31 Bacteria 1TR8N@1239,3F4CE@33958,4HB1D@91061,COG1501@1,COG1501@2 NA|NA|NA G Belongs to the glycosyl hydrolase 31 family FFAGCILK_00122 543734.LCABL_04770 6.8e-69 266.5 Lactobacillaceae 2.7.1.191 ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 Bacteria 1V7TP@1239,3F76S@33958,4IQPD@91061,COG2893@1,COG2893@2 NA|NA|NA G PTS system fructose IIA component FFAGCILK_00123 543734.LCABL_04780 0.0 1189.5 Lactobacillaceae malL 3.2.1.10 ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13 Bacteria 1TP53@1239,3F41I@33958,4HA1G@91061,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain protein FFAGCILK_00124 1423816.BACQ01000064_gene2451 2.5e-309 1067.4 Lactobacillaceae md2 ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,3F3PD@33958,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter FFAGCILK_00125 543734.LCABL_04810 7.8e-305 1052.4 Lactobacillaceae yfiB ko:K06147,ko:K18891 ko02010,map02010 M00708 ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.109,3.A.1.135,3.A.1.21 Bacteria 1TP0B@1239,3F63B@33958,4H9SC@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region FFAGCILK_00127 543734.LCABL_04840 0.0 1152.5 Lactobacillaceae pip ko:K01421 ko00000 Bacteria 1TQ15@1239,3F3Y3@33958,4H9T9@91061,COG1511@1,COG1511@2 NA|NA|NA V domain protein FFAGCILK_00128 568703.LGG_00474 1.8e-285 988.4 Bacilli Bacteria 1TQGI@1239,4HVRP@91061,COG2207@1,COG2207@2,COG3664@1,COG3664@2 NA|NA|NA GK helix_turn_helix, arabinose operon control protein FFAGCILK_00129 568703.LGG_00475 6.9e-191 673.3 Lactobacillaceae Bacteria 1UXYK@1239,3FCBT@33958,4HBU0@91061,COG2271@1,COG2271@2 NA|NA|NA G Major Facilitator Superfamily FFAGCILK_00130 568703.LGG_00476 1.2e-253 882.1 Lactobacillaceae abgB 3.5.1.47 ko:K05823,ko:K12941 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TQ7B@1239,3F5DP@33958,4HE6F@91061,COG1473@1,COG1473@2 NA|NA|NA S Peptidase dimerisation domain FFAGCILK_00131 543734.LCABL_04860 9.8e-155 552.7 Lactobacillaceae metQ_4 ko:K02073 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1V0Z6@1239,3FC6K@33958,4HBBW@91061,COG1464@1,COG1464@2 NA|NA|NA P Belongs to the nlpA lipoprotein family FFAGCILK_00132 543734.LCABL_04870 1.1e-197 695.7 Lactobacillaceae pac 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 Bacteria 1UZCV@1239,3FB8Y@33958,4HFHU@91061,COG3049@1,COG3049@2 NA|NA|NA M Linear amide C-N hydrolases, choloylglycine hydrolase family FFAGCILK_00133 1423816.BACQ01000064_gene2468 1.3e-83 316.6 Lactobacillaceae Bacteria 1U7BS@1239,29Q1F@1,30B00@2,3F9AV@33958,4IH72@91061 NA|NA|NA FFAGCILK_00134 543734.LCABL_04890 0.0 1140.9 Lactobacillaceae lai 4.2.1.53 ko:K10254 ko00000,ko01000 Bacteria 1TQZ6@1239,3F3QX@33958,4HAYH@91061,COG4716@1,COG4716@2 NA|NA|NA S Myosin-crossreactive antigen FFAGCILK_00135 543734.LCABL_04900 8.6e-15 85.1 Lactobacillaceae Bacteria 1U86E@1239,29QJ1@1,30BIK@2,3FAKU@33958,4II3Y@91061 NA|NA|NA FFAGCILK_00136 543734.LCABL_04910 4.5e-100 370.5 Lactobacillaceae Bacteria 1VCF7@1239,3FBG6@33958,4IQ66@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family FFAGCILK_00137 543734.LCABL_04920 7.3e-59 233.0 Lactobacillaceae dhaM GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047324 2.7.1.121 ko:K05881 ko00561,map00561 R01012 RC00015,RC00017 ko00000,ko00001,ko01000,ko02000 Bacteria 1VF32@1239,3F6YE@33958,4HKCN@91061,COG3412@1,COG3412@2 NA|NA|NA S PTS system fructose IIA component FFAGCILK_00138 543734.LCABL_04930 3.4e-103 380.9 Lactobacillaceae dhaL 2.7.1.121 ko:K05879 ko00561,ko01100,map00561,map01100 R01012 RC00015,RC00017 ko00000,ko00001,ko01000 Bacteria 1V4FH@1239,3F5VS@33958,4HGZY@91061,COG1461@1,COG1461@2 NA|NA|NA S Dak2 FFAGCILK_00139 543734.LCABL_04940 1.4e-189 668.7 Lactobacillaceae dhaK GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019637,GO:0019751,GO:0033554,GO:0034308,GO:0042180,GO:0042182,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0047324,GO:0050896,GO:0051716,GO:0061610,GO:0071704,GO:1901135,GO:1901575,GO:1901615 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 ko:K00863,ko:K05878,ko:K05879 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 M00344 R01011,R01012,R01059 RC00002,RC00015,RC00017 ko00000,ko00001,ko00002,ko01000 iEcHS_1320.EcHS_A1304,iUMNK88_1353.UMNK88_1515,iYL1228.KPN_03495 Bacteria 1TP92@1239,3F4F2@33958,4H9VS@91061,COG2376@1,COG2376@2 NA|NA|NA G Dak1 domain FFAGCILK_00140 543734.LCABL_04950 6.9e-77 293.1 Lactobacillaceae ohr Bacteria 1VY9T@1239,3F7CX@33958,4HXI7@91061,COG1764@1,COG1764@2 NA|NA|NA O OsmC-like protein FFAGCILK_00141 543734.LCABL_04960 2.8e-271 940.6 Lactobacillaceae Bacteria 1U7DD@1239,29Q2U@1,30B1F@2,3F9F1@33958,4IH99@91061 NA|NA|NA L Exonuclease FFAGCILK_00142 543734.LCABL_04970 9.4e-49 199.1 Lactobacillaceae Bacteria 1VAK2@1239,3F704@33958,4HMC7@91061,COG0640@1,COG0640@2 NA|NA|NA K Helix-turn-helix domain FFAGCILK_00143 543734.LCABL_04980 8.4e-202 709.5 Lactobacillaceae yceJ Bacteria 1TS6K@1239,3F4X1@33958,4HB1V@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily FFAGCILK_00144 543734.LCABL_04990 2.4e-107 394.8 Lactobacillaceae ko:K03892 ko00000,ko03000 Bacteria 1V007@1239,3F7E5@33958,4HDXJ@91061,COG0640@1,COG0640@2 NA|NA|NA K Transcriptional FFAGCILK_00145 543734.LCABL_05000 2.5e-106 391.3 Lactobacillaceae tag 3.2.2.20 ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1UYWG@1239,3F5KA@33958,4HGWW@91061,COG2818@1,COG2818@2 NA|NA|NA L glycosylase FFAGCILK_00146 1423816.BACQ01000064_gene2484 1e-167 595.9 Lactobacillaceae fba 4.1.2.13,4.1.2.29 ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568,R05378 RC00438,RC00439,RC00603,RC00604,RC00721 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ01@1239,3F4EF@33958,4H9ZU@91061,COG0191@1,COG0191@2 NA|NA|NA G Fructose-1,6-bisphosphate aldolase, class II FFAGCILK_00147 543734.LCABL_05020 0.0 1153.3 Lactobacillaceae poxB 1.2.3.3,1.2.5.1 ko:K00156,ko:K00158 ko00620,ko01100,map00620,map01100 R00207,R03145 RC00860,RC02745 ko00000,ko00001,ko01000 iSB619.SA_RS13340 Bacteria 1TQE8@1239,3F3R9@33958,4HBUS@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family FFAGCILK_00148 543734.LCABL_05030 7.9e-196 689.5 Lactobacillaceae Bacteria 1UZUZ@1239,3F969@33958,4IPQ5@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase FFAGCILK_00149 568703.LGG_00530 3.1e-150 538.1 Lactobacillaceae ykfB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 ko:K19802 R10938 RC03309 ko00000,ko01000 Bacteria 1TQMS@1239,3F4XQ@33958,4HCY5@91061,COG4948@1,COG4948@2 NA|NA|NA M Belongs to the mandelate racemase muconate lactonizing enzyme family FFAGCILK_00150 543734.LCABL_05040 1.3e-142 512.3 Lactobacillaceae Bacteria 1UIIR@1239,3F5MJ@33958,4ISJH@91061,COG2227@1,COG2227@2 NA|NA|NA H Protein of unknown function (DUF1698) FFAGCILK_00151 543734.LCABL_05050 1.7e-142 511.9 Lactobacillaceae puuD ko:K07010 ko00000,ko01002 Bacteria 1V1KC@1239,3F4PK@33958,4HI59@91061,COG2071@1,COG2071@2 NA|NA|NA S peptidase C26 FFAGCILK_00152 543734.LCABL_05060 8.1e-257 892.5 Bacilli 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 1U0IB@1239,4HTS7@91061,COG0174@1,COG0174@2 NA|NA|NA E Glutamine synthetase, catalytic domain FFAGCILK_00153 543734.LCABL_05070 1.9e-222 778.1 Bacilli ko:K07045 ko00000 Bacteria 1V9T6@1239,4HKS1@91061,COG2159@1,COG2159@2 NA|NA|NA S Amidohydrolase FFAGCILK_00154 543734.LCABL_05080 9.1e-248 862.4 Lactobacillaceae Bacteria 1V01X@1239,3F7SQ@33958,4HVQJ@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease FFAGCILK_00155 543734.LCABL_05090 6.5e-75 286.6 Lactobacillaceae Bacteria 1V3QI@1239,3F7ID@33958,4HH53@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance FFAGCILK_00156 543734.LCABL_05100 1.2e-163 582.4 Lactobacillaceae morA2 Bacteria 1TPM1@1239,3FB4S@33958,4HAG6@91061,COG0656@1,COG0656@2 NA|NA|NA S reductase FFAGCILK_00157 641146.HMPREF9020_01155 6.9e-200 703.0 Bifidobacteriales qor 1.1.1.1,1.6.5.5 ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 2GMHR@201174,4D00X@85004,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase FFAGCILK_00158 543734.LCABL_05120 2.9e-57 227.6 Lactobacillaceae hxlR Bacteria 1VA9M@1239,3F7S1@33958,4HH0A@91061,COG1733@1,COG1733@2 NA|NA|NA K Transcriptional regulator, HxlR family FFAGCILK_00159 543734.LCABL_05130 3.2e-96 357.8 Bacteria Bacteria COG2364@1,COG2364@2 NA|NA|NA FFAGCILK_00160 543734.LCABL_05140 2.4e-291 1007.3 Lactobacillaceae 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3FC7B@33958,4H9KU@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family FFAGCILK_00161 543734.LCABL_05150 4e-57 227.3 Lactobacillaceae 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 Bacteria 1VCD8@1239,3F8H7@33958,4HPQW@91061,COG1447@1,COG1447@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIA subunit FFAGCILK_00162 543734.LCABL_05160 8.1e-227 792.7 Lactobacillaceae GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016310,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0071704 2.7.1.207 ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 M00275,M00281 R04393,R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.1,4.A.3.2 Bacteria 1TP8D@1239,3F5XI@33958,4HBC9@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane FFAGCILK_00163 543734.LCABL_05170 1.5e-49 201.8 Lactobacillaceae 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 Bacteria 1VFYT@1239,3F8GJ@33958,4HPS6@91061,COG1440@1,COG1440@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit FFAGCILK_00164 543734.LCABL_05180 0.0 1210.3 Lactobacillaceae 2.7.1.194,2.7.1.200,2.7.1.202,2.7.1.204 ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 M00273,M00279,M00283,M00306,M00550,M00807 R03232,R05570,R07671,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1,4.A.5,4.A.5.1,4.A.7.1 Bacteria 1TQT1@1239,3F75H@33958,4HDAQ@91061,COG1762@1,COG1762@2,COG3711@1,COG3711@2 NA|NA|NA GKT Mga helix-turn-helix domain FFAGCILK_00165 543734.LCABL_05190 7e-104 383.3 Lactobacillaceae Bacteria 1V51N@1239,3F51V@33958,4HDX2@91061,COG1961@1,COG1961@2 NA|NA|NA L Resolvase, N terminal domain FFAGCILK_00166 543734.LCABL_05200 0.0 1763.8 Lactobacillaceae yvcC ko:K07114 ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 Bacteria 1V87P@1239,3F3PM@33958,4HA8Y@91061,COG2304@1,COG2304@2,COG4932@1,COG4932@2 NA|NA|NA M Cna protein B-type domain FFAGCILK_00167 543734.LCABL_05210 2.5e-124 451.4 Lactobacillaceae Bacteria 1U7CB@1239,3F9CF@33958,4IH7P@91061,COG4932@1,COG4932@2 NA|NA|NA M domain protein FFAGCILK_00168 543734.LCABL_05220 1.8e-184 651.7 Lactobacillaceae Bacteria 1W6HP@1239,3F9E7@33958,4HZUT@91061,COG4932@1,COG4932@2 NA|NA|NA M LPXTG cell wall anchor motif FFAGCILK_00169 543734.LCABL_05230 3.3e-200 704.1 Lactobacillaceae 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria 1V1RS@1239,3FCAC@33958,4HHRS@91061,COG3764@1,COG3764@2 NA|NA|NA M Sortase family FFAGCILK_00170 543734.LCABL_05240 1.1e-127 462.6 Lactobacillaceae XK27_12140 ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TRTC@1239,3F59T@33958,4HG0J@91061,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities FFAGCILK_00171 543734.LCABL_05250 1.5e-297 1028.1 Lactobacillaceae Bacteria 1TQV6@1239,28IHZ@1,2Z8J5@2,3F5NC@33958,4HPC9@91061 NA|NA|NA S Psort location CytoplasmicMembrane, score FFAGCILK_00172 543734.LCABL_05260 1e-125 456.1 Lactobacillaceae Bacteria 1TQ0D@1239,3F536@33958,4HHWT@91061,COG0745@1,COG0745@2 NA|NA|NA K Transcriptional regulatory protein, C terminal FFAGCILK_00173 543734.LCABL_05270 6.2e-194 683.3 Lactobacillaceae Bacteria 1TS1G@1239,3F4NF@33958,4HBC0@91061,COG0642@1,COG2205@2 NA|NA|NA T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain FFAGCILK_00174 543734.LCABL_05290 9.1e-140 503.1 Lactobacillaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TRJH@1239,3F5Y2@33958,4HD67@91061,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities FFAGCILK_00175 543734.LCABL_05300 2e-208 731.5 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1UYXD@1239,28IVE@1,2Z8TU@2,3F500@33958,4HMX1@91061 NA|NA|NA FFAGCILK_00176 543734.LCABL_05310 3.3e-91 341.3 Lactobacillaceae Bacteria 1U667@1239,2CZFI@1,30A49@2,3F761@33958,4IFWD@91061 NA|NA|NA FFAGCILK_00177 543734.LCABL_05320 0.0 2896.3 Lactobacillaceae Bacteria 1TPH1@1239,3F3M5@33958,4HBQH@91061,COG1404@1,COG1404@2 NA|NA|NA O Belongs to the peptidase S8 family FFAGCILK_00178 543734.LCABL_05330 0.0 2800.8 Lactobacillaceae Bacteria 1TPH1@1239,3F3M5@33958,4HBQH@91061,COG1404@1,COG1404@2 NA|NA|NA O Belongs to the peptidase S8 family FFAGCILK_00179 543734.LCABL_05340 0.0 1681.4 Lactobacillaceae pepN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.2 ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 1TR43@1239,3F3UH@33958,4HA20@91061,COG0308@1,COG0308@2 NA|NA|NA E aminopeptidase FFAGCILK_00180 543734.LCABL_05350 7.8e-274 949.1 Lactobacillaceae ycaM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 1TRFS@1239,3FCAH@33958,4HBIP@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid FFAGCILK_00181 543734.LCABL_05360 1.3e-77 295.8 Lactobacillaceae ko:K08996 ko00000 Bacteria 1VX0K@1239,3F6A5@33958,4HX2R@91061,COG3477@1,COG3477@2 NA|NA|NA S Protein of unknown function (DUF1440) FFAGCILK_00182 543734.LCABL_05370 5.4e-164 583.6 Lactobacillaceae Bacteria 1TRVX@1239,3F48I@33958,4HFSV@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator, LysR family FFAGCILK_00183 1423732.BALS01000043_gene2705 1.2e-160 572.4 Lactobacillaceae Bacteria 1TT50@1239,3F5RA@33958,4HCNS@91061,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase-like TIM barrel FFAGCILK_00184 1423816.BACQ01000064_gene2507 1.7e-140 505.4 Lactobacillaceae Bacteria 1TRFT@1239,3F4HT@33958,4HCX7@91061,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase FFAGCILK_00185 543734.LCABL_05410 3.3e-161 574.3 Lactobacillaceae aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQRY@1239,3F5MZ@33958,4HD4R@91061,COG0169@1,COG0169@2 NA|NA|NA E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) FFAGCILK_00186 543734.LCABL_05420 2.9e-213 747.7 Lactobacillaceae ydiN ko:K03762 ko00000,ko02000 2.A.1.6.4 Bacteria 1TS50@1239,3FBTT@33958,4HNF2@91061,COG0477@1,COG0477@2 NA|NA|NA EGP Major Facilitator Superfamily FFAGCILK_00187 543734.LCABL_05430 6.2e-168 596.7 Lactobacillaceae aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0030266,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0052734,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25,1.1.1.282,1.3.5.4 ko:K00014,ko:K00244,ko:K05887 ko00020,ko00190,ko00400,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko02020,map00020,map00190,map00400,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map01230,map02020 M00009,M00011,M00022,M00150,M00173 R01872,R02164,R02413,R06846,R06847 RC00045,RC00154,RC00206 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS14185,iSFxv_1172.SFxv_1929,iS_1188.S1854 Bacteria 1TQRY@1239,3F4WM@33958,4HD4R@91061,COG0169@1,COG0169@2 NA|NA|NA E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) FFAGCILK_00188 543734.LCABL_05440 8.1e-159 566.2 Lactobacillaceae metAA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0008899,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS11970 Bacteria 1TQVR@1239,3F5CA@33958,4H9W4@91061,COG1897@1,COG1897@2 NA|NA|NA E Transfers an acetyl group from acetyl-CoA to FFAGCILK_00189 543734.LCABL_05450 2.9e-173 614.4 Lactobacillaceae cysK GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP30@1239,3F4VD@33958,4HAMU@91061,COG0031@1,COG0031@2 NA|NA|NA E Belongs to the cysteine synthase cystathionine beta- synthase family FFAGCILK_00190 1423807.BACO01000071_gene2220 1.3e-27 129.8 Bacilli Bacteria 1VPBI@1239,28WK8@1,33J6A@2,4HRFN@91061 NA|NA|NA FFAGCILK_00192 1423816.BACQ01000064_gene2513 4.3e-222 776.9 Lactobacillaceae Bacteria 1TPE1@1239,3F3NJ@33958,4HA65@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family FFAGCILK_00193 1423732.BALS01000098_gene1435 2.2e-09 68.2 Lactobacillaceae Bacteria 1U7AM@1239,29Q0P@1,30AZ5@2,3F97Y@33958,4IH5K@91061 NA|NA|NA FFAGCILK_00196 543734.LCABL_05530 7.8e-134 483.0 Lactobacillaceae Bacteria 1U8A0@1239,29QKX@1,30BKI@2,3FAR9@33958,4II7Y@91061 NA|NA|NA FFAGCILK_00197 1423732.BALS01000070_gene2074 6e-20 104.0 Bacilli Bacteria 1W1K0@1239,4I17Z@91061,COG2856@1,COG2856@2 NA|NA|NA E Zn peptidase FFAGCILK_00198 543734.LCABL_05550 7.5e-61 239.6 Lactobacillaceae ps115 Bacteria 1VEP9@1239,3F871@33958,4HPCR@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins FFAGCILK_00201 543734.LCABL_05570 1e-156 559.3 Bacilli ps305 Bacteria 1V8EG@1239,28IYH@1,2Z8W7@2,4HJXX@91061 NA|NA|NA S Protein of unknown function (Hypoth_ymh) FFAGCILK_00202 1423816.BACQ01000064_gene2518 6e-137 493.4 Lactobacillaceae Bacteria 1VEBK@1239,3FBM1@33958,4IR34@91061,COG3646@1,COG3646@2 NA|NA|NA S ORF6N domain FFAGCILK_00203 1423816.BACQ01000064_gene2520 7.8e-44 182.6 Bacilli Bacteria 1VQHP@1239,2AESZ@1,314PW@2,4HZNT@91061 NA|NA|NA S Domain of unknown function (DUF1883) FFAGCILK_00209 1423816.BACQ01000064_gene2523 7.7e-140 503.1 Lactobacillaceae Bacteria 1VHK1@1239,3FCF5@33958,4HQY7@91061,COG3935@1,COG3935@2 NA|NA|NA L Helix-turn-helix domain FFAGCILK_00210 543734.LCABL_05660 3.2e-155 554.3 Lactobacillaceae dnaC ko:K02315 ko00000,ko03032 Bacteria 1TPKM@1239,3F6BK@33958,4HH4U@91061,COG1484@1,COG1484@2 NA|NA|NA L IstB-like ATP binding protein FFAGCILK_00212 1423816.BACQ01000064_gene2526 6.2e-70 270.0 Lactobacillaceae Bacteria 1VFNJ@1239,2BZYB@1,331KR@2,3F7VM@33958,4HPGT@91061 NA|NA|NA FFAGCILK_00213 1423816.BACQ01000064_gene2527 1.1e-133 482.6 Lactobacillaceae Bacteria 1V1NK@1239,28PQ6@1,2ZCCB@2,3F6J4@33958,4HGG6@91061 NA|NA|NA FFAGCILK_00215 543734.LCABL_05720 3.4e-79 300.8 Bacilli Bacteria 1W51N@1239,2DCNS@1,2ZESF@2,4I1NU@91061 NA|NA|NA FFAGCILK_00217 543734.LCABL_03570 5e-187 660.2 Lactobacillaceae Bacteria 1TRSF@1239,3F3UG@33958,4HDM3@91061,COG2826@1,COG2826@2 NA|NA|NA L PFAM Integrase, catalytic core FFAGCILK_00220 543734.LCABL_05760 1.8e-158 565.1 Bacilli Bacteria 1VQQP@1239,2C1BV@1,33HNE@2,4HWNS@91061 NA|NA|NA FFAGCILK_00221 1423816.BACQ01000026_gene949 1.4e-49 201.8 Bacilli Bacteria 1VQQP@1239,2C1BV@1,33HNE@2,4HWNS@91061 NA|NA|NA FFAGCILK_00222 543734.LCABL_05780 3.1e-56 224.2 Lactobacillaceae Bacteria 1U6SS@1239,2BWYP@1,30AJY@2,3F8F9@33958,4IGKB@91061 NA|NA|NA FFAGCILK_00223 1423816.BACQ01000066_gene2531 5.6e-52 209.9 Lactobacillaceae ko:K07483 ko00000 Bacteria 1VQ03@1239,3F77N@33958,4HS9H@91061,COG2963@1,COG2963@2 NA|NA|NA L 4.5 Transposon and IS FFAGCILK_00224 543734.LCABL_05800 8.6e-136 489.6 Lactobacillaceae ko:K07483 ko00000 Bacteria 1V1QC@1239,3F65F@33958,4HH7E@91061,COG2963@1,COG2963@2 NA|NA|NA L Helix-turn-helix domain FFAGCILK_00225 543734.LCABL_05810 3.9e-167 594.0 Lactobacillaceae Bacteria 1TQEG@1239,3F43M@33958,4HD6M@91061,COG2801@1,COG2801@2 NA|NA|NA L hmm pf00665 FFAGCILK_00226 1423816.BACQ01000066_gene2535 9.8e-155 552.7 Lactobacillaceae ko:K07497 ko00000 Bacteria 1VSY9@1239,3F563@33958,4HUYS@91061,COG2801@1,COG2801@2 NA|NA|NA L 4.5 Transposon and IS FFAGCILK_00230 1423732.BALS01000054_gene2738 5.2e-31 139.8 Bacilli Bacteria 1VQ12@1239,2C3WB@1,33NQV@2,4HSYA@91061 NA|NA|NA FFAGCILK_00231 543734.LCABL_05870 5.1e-205 720.3 Bacilli Bacteria 1VP01@1239,2EG0H@1,339SH@2,4HS1I@91061 NA|NA|NA FFAGCILK_00232 1423816.BACQ01000066_gene2540 4e-207 727.6 Bacilli Bacteria 1V9ZD@1239,4ITN8@91061,COG4932@1,COG4932@2 NA|NA|NA M Domain of unknown function (DUF5011) FFAGCILK_00235 543734.LCABL_05910 0.0 1481.1 Lactobacillaceae ko:K03205 ko03070,map03070 M00333 ko00000,ko00001,ko00002,ko02044 3.A.7 Bacteria 1TPCF@1239,3F4S3@33958,4H9ZN@91061,COG3505@1,COG3505@2 NA|NA|NA U TraM recognition site of TraD and TraG FFAGCILK_00236 543734.LCABL_05920 3.1e-276 957.6 Bacilli 5.4.99.21 ko:K06182 ko00000,ko01000,ko03009 Bacteria 1TSNJ@1239,4HEFK@91061,COG3266@1,COG3266@2 NA|NA|NA S domain, Protein FFAGCILK_00238 1423732.BALS01000054_gene2749 6.9e-107 393.3 Firmicutes Bacteria 1V94J@1239,2DME1@1,32QVI@2 NA|NA|NA FFAGCILK_00239 1423816.BACQ01000066_gene2547 0.0 1283.1 Lactobacillaceae trsE Bacteria 1W186@1239,3F6HE@33958,4HA4T@91061,COG0433@1,COG0433@2 NA|NA|NA S COG0433 Predicted ATPase FFAGCILK_00240 543734.LCABL_05960 1.6e-177 628.6 Bacteria ko:K21471,ko:K21472 ko00000,ko01000,ko01002,ko01011 Bacteria COG0739@1,COG0739@2,COG0791@1,COG0791@2 NA|NA|NA M cysteine-type peptidase activity FFAGCILK_00247 1423732.BALS01000076_gene2137 2.1e-219 768.1 Lactobacillaceae 3.1.1.32,3.1.1.4 ko:K01058,ko:K07502 ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110 R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860 RC00020,RC00037,RC00041,RC00094 ko00000,ko00001,ko01000 Bacteria 1UHSY@1239,3F8F0@33958,4IS8P@91061,COG0790@1,COG0790@2 NA|NA|NA S COG0790 FOG TPR repeat, SEL1 subfamily FFAGCILK_00249 543734.LCABL_06050 0.0 1583.9 Lactobacillaceae Bacteria 1TQN4@1239,3F8MI@33958,4HKTX@91061,COG0358@1,COG0358@2,COG4227@1,COG4227@2 NA|NA|NA L Protein of unknown function (DUF3991) FFAGCILK_00250 543734.LCABL_06080 9.9e-18 95.1 Lactobacillaceae Bacteria 1W17P@1239,2ED72@1,3373P@2,3FADZ@33958,4HXZS@91061 NA|NA|NA FFAGCILK_00251 1423732.BALS01000076_gene2134 9.6e-34 149.1 Lactobacillaceae Bacteria 1W17P@1239,2ED72@1,3373P@2,3FADZ@33958,4HXZS@91061 NA|NA|NA FFAGCILK_00252 1423816.BACQ01000066_gene2559 1.8e-16 90.9 Bacteria Bacteria 293FZ@1,2ZQYB@2 NA|NA|NA FFAGCILK_00253 1423732.BALS01000076_gene2132 1.7e-78 298.5 Bacteria Bacteria 2DUJT@1,33R01@2 NA|NA|NA FFAGCILK_00255 543734.LCABL_06130 2.1e-76 291.6 Bacteria Bacteria 2F273@1,33V59@2 NA|NA|NA FFAGCILK_00256 543734.LCABL_06140 2.9e-118 431.4 Lactobacillaceae ko:K15051 ko00000 Bacteria 1TR37@1239,3FC9V@33958,4HK7D@91061,COG2169@1,COG2169@2 NA|NA|NA F DNA/RNA non-specific endonuclease FFAGCILK_00258 1423747.BAMJ01000014_gene1104 1.4e-16 92.0 Lactobacillaceae Bacteria 1U8JK@1239,29MVS@1,308TH@2,3FB21@33958,4IIHJ@91061 NA|NA|NA FFAGCILK_00260 169963.lmo0425 5.1e-103 382.1 Listeriaceae 2.7.1.197,2.7.1.200,2.7.1.202 ko:K02538,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02798,ko:K03483,ko:K03491 ko00051,ko00052,ko01100,ko01120,ko02060,map00051,map00052,map01100,map01120,map02060 M00273,M00274,M00279 R02704,R03232,R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1,4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5,4.A.5.1 Bacteria 1TQT1@1239,26J70@186820,4HB6A@91061,COG1762@1,COG1762@2,COG3711@1,COG3711@2 NA|NA|NA G Mga helix-turn-helix domain FFAGCILK_00261 1265845.PWEIH_07161 7.2e-29 133.7 Listeriaceae 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 Bacteria 1VA2N@1239,26KIJ@186820,4HKD2@91061,COG1762@1,COG1762@2 NA|NA|NA G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 FFAGCILK_00262 1027396.LMOSA_13260 5.1e-32 143.7 Listeriaceae fruA 2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K11202 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273,M00306 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 Bacteria 1VC69@1239,26KVX@186820,4HK6H@91061,COG1445@1,COG1445@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit FFAGCILK_00263 1265845.PWEIH_07151 7e-137 493.8 Listeriaceae 2.7.1.195 ko:K02770,ko:K11198,ko:K11199,ko:K11200 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273,M00305 R03232,R11169 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.2.1.3 Bacteria 1UYP2@1239,26JQI@186820,4HE20@91061,COG1299@1,COG1299@2 NA|NA|NA G PTS mannose transporter subunit IIAB FFAGCILK_00264 525367.HMPREF0556_10672 7.4e-206 724.2 Listeriaceae 3.2.1.170,3.2.1.24 ko:K01191,ko:K15524 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 GH38 Bacteria 1TQEH@1239,26JBJ@186820,4HBC7@91061,COG0383@1,COG0383@2 NA|NA|NA G Glycosyl hydrolase FFAGCILK_00265 1121105.ATXL01000019_gene1512 3.3e-70 271.9 Enterococcaceae glcU ko:K05340 ko00000,ko02000 2.A.7.5 Bacteria 1TQBN@1239,4AZVB@81852,4HAVH@91061,COG4975@1,COG4975@2 NA|NA|NA G Sugar transport protein FFAGCILK_00266 1400520.LFAB_14930 2.6e-44 185.7 Lactobacillaceae ko:K10984 ko00052,ko02060,map00052,map02060 M00287 R08367 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1.5 Bacteria 1UIXK@1239,3F68S@33958,4ISVV@91061,COG2188@1,COG2188@2 NA|NA|NA K UTRA domain FFAGCILK_00267 1400520.LFAB_14935 3.6e-66 257.7 Lactobacillaceae agaB 2.7.1.191 ko:K02794,ko:K10984 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 M00276,M00287 R02630,R08367 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1,4.A.6.1.5 iB21_1397.B21_02956,iEC55989_1330.EC55989_3558,iECBD_1354.ECBD_0602,iECB_1328.ECB_03005,iECD_1391.ECD_03005,iECIAI1_1343.ECIAI1_3288,iECIAI39_1322.ECIAI39_3639,iECO103_1326.ECO103_3885,iECO111_1330.ECO111_3962,iECO26_1355.ECO26_4243,iECSE_1348.ECSE_3424,iECW_1372.ECW_m3408,iEKO11_1354.EKO11_0579,iEcE24377_1341.EcE24377A_3620,iEcSMS35_1347.EcSMS35_3437,iEcolC_1368.EcolC_0560,iUMNK88_1353.UMNK88_3897,iWFL_1372.ECW_m3408 Bacteria 1TQJ4@1239,3F5PA@33958,4HI37@91061,COG3444@1,COG3444@2 NA|NA|NA K PTS system sorbose subfamily IIB component FFAGCILK_00268 220668.lp_2649 7.3e-120 436.8 Lactobacillaceae agaC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034219,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 ko:K10985 ko00052,ko02060,map00052,map02060 M00287 R08367 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1.5 Bacteria 1TPKK@1239,3F4YT@33958,4HC0V@91061,COG3715@1,COG3715@2 NA|NA|NA G PTS system sorbose-specific iic component FFAGCILK_00269 1423775.BAMN01000002_gene1999 2e-117 428.7 Lactobacillaceae ko:K02796,ko:K10986 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 M00276,M00287 R02630,R08367 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.5 Bacteria 1TQA3@1239,3F4YA@33958,4HD65@91061,COG3716@1,COG3716@2 NA|NA|NA G PTS system mannose/fructose/sorbose family IID component FFAGCILK_00270 1400520.LFAB_14950 4.9e-30 137.5 Lactobacillaceae ko:K02744 ko00052,ko02060,map00052,map02060 M00277,M00287 R08366,R08367 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1.4,4.A.6.1.5 Bacteria 1VC2D@1239,3FBI6@33958,4HXQW@91061,COG2893@1,COG2893@2 NA|NA|NA G PTS system fructose IIA component FFAGCILK_00271 1133569.AHYZ01000177_gene359 1.8e-26 124.4 Lactobacillaceae Bacteria 1U6KZ@1239,29PHS@1,30AFX@2,3F84Q@33958,4IGDS@91061 NA|NA|NA FFAGCILK_00272 1437603.BMON_1228 2e-255 887.9 Bifidobacteriales ykgC GO:0000302,GO:0000305,GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0019725,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901530,GO:1901700,GO:1990748 1.16.1.1,1.8.1.7 ko:K00383,ko:K00520,ko:K21739 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 Bacteria 2GJJK@201174,4CZZF@85004,COG1249@1,COG1249@2 NA|NA|NA C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family FFAGCILK_00273 568703.LGG_00437 3.2e-46 190.7 Lactobacillaceae ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972,ko:K10754 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 M00289,M00295 R00382 RC00005 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1W4JC@1239,3F83P@33958,4I09W@91061,COG0272@1,COG0272@2 NA|NA|NA L BRCA1 C Terminus (BRCT) domain FFAGCILK_00274 1423816.BACQ01000039_gene1601 2.6e-115 421.4 Lactobacillaceae Bacteria 1TQAX@1239,3FBG4@33958,4IQ61@91061,COG1961@1,COG1961@2 NA|NA|NA L Resolvase, N terminal domain FFAGCILK_00275 543734.LCABL_06580 1.4e-49 202.2 Lactobacillaceae Bacteria 1W5K5@1239,28ZBI@1,2ZM3D@2,3F825@33958,4I1Q6@91061 NA|NA|NA S Protein of unknown function (DUF1093) FFAGCILK_00277 1074451.CRL705_1934 4.9e-84 317.0 Lactobacillaceae dps ko:K04047 ko00000,ko03036 Bacteria 1VCVJ@1239,3F5WI@33958,4HMBD@91061,COG0783@1,COG0783@2 NA|NA|NA P Belongs to the Dps family FFAGCILK_00278 1122149.BACN01000114_gene4 2.1e-154 551.6 Lactobacillaceae Bacteria 1TU21@1239,3F46G@33958,4HDK4@91061,COG2801@1,COG2801@2 NA|NA|NA L Integrase core domain FFAGCILK_00279 1136177.KCA1_1226 6e-105 386.7 Lactobacillaceae Bacteria 1UPXG@1239,2AYWY@1,31R2N@2,3F66A@33958,4IVCM@91061 NA|NA|NA FFAGCILK_00281 1074451.CRL705_1346 1.5e-16 90.9 Lactobacillaceae ko:K07483 ko00000 Bacteria 1VIEV@1239,3F6X7@33958,4HJSC@91061,COG2963@1,COG2963@2 NA|NA|NA L Transposase and inactivated derivatives FFAGCILK_00282 1122149.BACN01000114_gene4 1.1e-153 549.3 Lactobacillaceae Bacteria 1TU21@1239,3F46G@33958,4HDK4@91061,COG2801@1,COG2801@2 NA|NA|NA L Integrase core domain FFAGCILK_00283 543734.LCABL_06470 2e-163 581.6 Lactobacillaceae apbE 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria 1TR9C@1239,3FB4A@33958,4HDFE@91061,COG1477@1,COG1477@2 NA|NA|NA H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein FFAGCILK_00284 543734.LCABL_06480 9.1e-107 392.9 Lactobacillaceae XK27_09620 Bacteria 1TT2S@1239,3F544@33958,4HBQI@91061,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase FFAGCILK_00285 543734.LCABL_06490 1e-240 839.0 Lactobacillaceae XK27_09615 Bacteria 1TPRA@1239,3F44U@33958,4HDA5@91061,COG0431@1,COG0431@2,COG2461@1,COG2461@2 NA|NA|NA S reductase FFAGCILK_00286 525318.HMPREF0497_1019 6.7e-72 276.6 Lactobacillaceae GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 Bacteria 1VGE7@1239,3F6YB@33958,4HNE7@91061,COG3576@1,COG3576@2 NA|NA|NA S pyridoxamine 5-phosphate FFAGCILK_00287 525318.HMPREF0497_1020 7.9e-11 72.4 Lactobacillaceae Bacteria 1TPGA@1239,3F4HK@33958,4HER3@91061,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase FFAGCILK_00288 543734.LCABL_03570 3.2e-14 84.0 Lactobacillaceae Bacteria 1TRSF@1239,3F3UG@33958,4HDM3@91061,COG2826@1,COG2826@2 NA|NA|NA L PFAM Integrase, catalytic core FFAGCILK_00289 543734.LCABL_21480 5.8e-126 456.8 Lactobacillaceae tnp ko:K07498 ko00000 Bacteria 1TTKR@1239,3F4NE@33958,4HCB4@91061,COG3316@1,COG3316@2 NA|NA|NA L DDE domain FFAGCILK_00290 543734.LCABL_21290 1.5e-61 241.9 Lactobacillaceae Bacteria 1TQ93@1239,3F4RD@33958,4HDNZ@91061,COG3464@1,COG3464@2 NA|NA|NA L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein FFAGCILK_00291 1423734.JCM14202_2841 1.4e-74 285.4 Lactobacillaceae arsC GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 ko:K03741 ko00000,ko01000 Bacteria 1V3JW@1239,3F6GQ@33958,4HH49@91061,COG0394@1,COG0394@2 NA|NA|NA T Belongs to the low molecular weight phosphotyrosine protein phosphatase family FFAGCILK_00292 1423734.JCM14202_2840 4.1e-56 223.8 Lactobacillaceae arsD Bacteria 1VB95@1239,2DMHQ@1,32RMG@2,3F7T6@33958,4HKKS@91061 NA|NA|NA S Arsenical resistance operon trans-acting repressor ArsD FFAGCILK_00293 1423734.JCM14202_2839 1.8e-119 435.3 Lactobacillaceae arsB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008490,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042960,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 ko:K03893 ko00000,ko02000 2.A.45.1,3.A.4.1 iAF1260.b3502,iB21_1397.B21_03304,iBWG_1329.BWG_3192,iECBD_1354.ECBD_0238,iECB_1328.ECB_03351,iECDH10B_1368.ECDH10B_3678,iECDH1ME8569_1439.ECDH1ME8569_3381,iECD_1391.ECD_03351,iECH74115_1262.ECH74115_4851,iECIAI1_1343.ECIAI1_3649,iECO103_1326.ECO103_4229,iECO111_1330.ECO111_4311,iECO26_1355.ECO26_4590,iECSE_1348.ECSE_3768,iECSP_1301.ECSP_4482,iECs_1301.ECs4374,iETEC_1333.ETEC_3749,iEcDH1_1363.EcDH1_0212,iEcE24377_1341.EcE24377A_3985,iEcHS_1320.EcHS_A3704,iEcolC_1368.EcolC_0214,iG2583_1286.G2583_4228,iJO1366.b3502,iSFV_1184.SFV_3514,iSF_1195.SF3535,iS_1188.S4233,iUMNK88_1353.UMNK88_4279,iY75_1357.Y75_RS19690,iZ_1308.Z4904 Bacteria 1TPNN@1239,3F5JS@33958,4H9WV@91061,COG1055@1,COG1055@2 NA|NA|NA U Involved in arsenical resistance. Thought to form the channel of an arsenite pump FFAGCILK_00294 1423732.BALS01000046_gene2610 4.8e-91 340.5 Lactobacillaceae arsB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008490,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042960,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 ko:K03893 ko00000,ko02000 2.A.45.1,3.A.4.1 iAF1260.b3502,iB21_1397.B21_03304,iBWG_1329.BWG_3192,iECBD_1354.ECBD_0238,iECB_1328.ECB_03351,iECDH10B_1368.ECDH10B_3678,iECDH1ME8569_1439.ECDH1ME8569_3381,iECD_1391.ECD_03351,iECH74115_1262.ECH74115_4851,iECIAI1_1343.ECIAI1_3649,iECO103_1326.ECO103_4229,iECO111_1330.ECO111_4311,iECO26_1355.ECO26_4590,iECSE_1348.ECSE_3768,iECSP_1301.ECSP_4482,iECs_1301.ECs4374,iETEC_1333.ETEC_3749,iEcDH1_1363.EcDH1_0212,iEcE24377_1341.EcE24377A_3985,iEcHS_1320.EcHS_A3704,iEcolC_1368.EcolC_0214,iG2583_1286.G2583_4228,iJO1366.b3502,iSFV_1184.SFV_3514,iSF_1195.SF3535,iS_1188.S4233,iUMNK88_1353.UMNK88_4279,iY75_1357.Y75_RS19690,iZ_1308.Z4904 Bacteria 1TPNN@1239,3F5JS@33958,4H9WV@91061,COG1055@1,COG1055@2 NA|NA|NA U Involved in arsenical resistance. Thought to form the channel of an arsenite pump FFAGCILK_00295 1423734.JCM14202_2838 0.0 1121.7 Lactobacillaceae arsA 3.6.3.16 ko:K01551 ko00000,ko01000,ko02000 3.A.19.1,3.A.21.1,3.A.4.1 Bacteria 1TQZP@1239,3F4XI@33958,4HBKG@91061,COG0003@1,COG0003@2 NA|NA|NA D Anion-transporting ATPase FFAGCILK_00296 1423734.JCM14202_2837 2.7e-57 227.6 Lactobacillaceae arsR ko:K03892 ko00000,ko03000 Bacteria 1VEER@1239,3FB54@33958,4HMIJ@91061,COG0640@1,COG0640@2 NA|NA|NA K Helix-turn-helix domain FFAGCILK_00297 1423732.BALS01000046_gene2607 3.9e-102 377.5 Lactobacillaceae tnpR2 Bacteria 1UZT3@1239,3F533@33958,4HEGY@91061,COG1961@1,COG1961@2 NA|NA|NA L Helix-turn-helix domain of resolvase FFAGCILK_00298 1423732.BALS01000046_gene2606 4.5e-42 176.8 Lactobacillaceae Bacteria 1TRGX@1239,3F4XC@33958,4HAJF@91061,COG4584@1,COG4584@2,COG4644@1,COG4644@2 NA|NA|NA L Domain of unknown function (DUF4158) FFAGCILK_00299 891391.LAC30SC_01325 2.2e-20 104.8 Lactobacillaceae 2.1.1.72 ko:K00571 ko00000,ko01000,ko02048 Bacteria 1TT2W@1239,2DB9A@1,2Z7VI@2,3F85D@33958,4HMYR@91061 NA|NA|NA S Adenine-specific methyltransferase EcoRI FFAGCILK_00300 511437.Lbuc_0406 9.1e-113 412.9 Lactobacillaceae ybbL GO:0005575,GO:0005623,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0016020,GO:0019725,GO:0030003,GO:0042592,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071944,GO:0098771 ko:K02065,ko:K02068 ko02010,map02010 M00210,M00211,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 1V3DQ@1239,3F4UY@33958,4HHGU@91061,COG4619@1,COG4619@2 NA|NA|NA S ABC transporter, ATP-binding protein FFAGCILK_00301 511437.Lbuc_0405 2.9e-126 458.0 Lactobacillaceae ybbM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 ko:K02069 M00211 ko00000,ko00002,ko02000 9.B.25.1 Bacteria 1UY1N@1239,3F4P1@33958,4HDM4@91061,COG0390@1,COG0390@2 NA|NA|NA S Uncharacterised protein family (UPF0014) FFAGCILK_00302 1071400.LBUCD034_0440 5e-243 846.7 Lactobacillaceae ko:K03292,ko:K16209,ko:K16210 ko00000,ko02000 2.A.2,2.A.2.2,2.A.2.5 Bacteria 1VRWM@1239,3FBC3@33958,4HTJK@91061,COG2211@1,COG2211@2 NA|NA|NA G MFS/sugar transport protein FFAGCILK_00303 543734.LCABL_06610 2.4e-144 518.1 Lactobacillaceae Bacteria 1V5SH@1239,2DMZ9@1,32UJF@2,3F68Q@33958,4HKAC@91061 NA|NA|NA FFAGCILK_00304 543734.LCABL_06620 1.1e-211 742.3 Lactobacillaceae metC 4.4.1.8 ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPC7@1239,3F3Y2@33958,4HAFQ@91061,COG0626@1,COG0626@2 NA|NA|NA E cystathionine FFAGCILK_00305 543734.LCABL_06630 5.1e-145 520.4 Lactobacillaceae tcyA ko:K02424,ko:K10009,ko:K16957 ko02010,map02010 M00234,M00585 ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3.10,3.A.1.3.13,3.A.1.3.14 Bacteria 1TR13@1239,3F4MH@33958,4HBRP@91061,COG0834@1,COG0834@2 NA|NA|NA ET Belongs to the bacterial solute-binding protein 3 family FFAGCILK_00306 543734.LCABL_06640 6.9e-122 443.4 Lactobacillaceae tcyB GO:0000099,GO:0000101,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015184,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015811,GO:0015849,GO:0016020,GO:0022857,GO:0033229,GO:0034220,GO:0042883,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:0098655,GO:0098656,GO:1901682,GO:1902475,GO:1903712,GO:1903825,GO:1905039 ko:K02424,ko:K10009 ko02010,map02010 M00234 ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3.10,3.A.1.3.14 iYO844.BSU03600 Bacteria 1TPQ8@1239,3F4QR@33958,4H9N1@91061,COG0765@1,COG0765@2 NA|NA|NA E ABC transporter FFAGCILK_00307 1423816.BACQ01000040_gene1607 1.7e-32 146.7 Lactobacillaceae Bacteria 1U7KY@1239,29Q72@1,30B62@2,3F9VZ@33958,4IHI1@91061 NA|NA|NA FFAGCILK_00308 543734.LCABL_06660 9.6e-253 879.0 Lactobacillaceae brnQ GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903785,GO:1903825,GO:1905039 ko:K03311 ko00000 2.A.26 Bacteria 1TQIS@1239,3F3KC@33958,4HAKA@91061,COG1114@1,COG1114@2 NA|NA|NA U Component of the transport system for branched-chain amino acids FFAGCILK_00309 543734.LCABL_06680 7.4e-118 429.9 Firmicutes Bacteria 1UM02@1239,2DDU7@1,2ZJAU@2 NA|NA|NA S WxL domain surface cell wall-binding FFAGCILK_00310 543734.LCABL_06690 9.4e-173 612.8 Lactobacillaceae Bacteria 1VCXS@1239,3F5HA@33958,4HKJG@91061,COG4072@1,COG4072@2 NA|NA|NA S Cell surface protein FFAGCILK_00311 543734.LCABL_06700 4.2e-25 120.9 Lactobacillaceae Bacteria 1U7ZW@1239,2AIBJ@1,318SM@2,3FAD9@33958,4IHXA@91061 NA|NA|NA FFAGCILK_00312 543734.LCABL_06710 0.0 1270.0 Lactobacillaceae XK27_00720 ko:K13730 ko05100,map05100 ko00000,ko00001 Bacteria 1UVV2@1239,3F806@33958,4I2C5@91061,COG4886@1,COG4886@2 NA|NA|NA S Leucine-rich repeat (LRR) protein FFAGCILK_00313 543734.LCABL_06730 3.7e-47 194.1 Bacteria Bacteria 2DDU7@1,2ZJAU@2 NA|NA|NA S WxL domain surface cell wall-binding FFAGCILK_00314 543734.LCABL_06730 1e-57 229.2 Bacteria Bacteria 2DDU7@1,2ZJAU@2 NA|NA|NA S WxL domain surface cell wall-binding FFAGCILK_00315 543734.LCABL_06740 6.7e-57 226.5 Lactobacillaceae Bacteria 1U8F4@1239,29QPU@1,30BPI@2,3FAWZ@33958,4IID0@91061 NA|NA|NA FFAGCILK_00316 543734.LCABL_06750 1.1e-103 382.9 Lactobacillaceae Bacteria 1W54S@1239,3F5H0@33958,4IF30@91061,COG5492@1,COG5492@2 NA|NA|NA N WxL domain surface cell wall-binding FFAGCILK_00318 543734.LCABL_06760 0.0 1360.5 Lactobacillaceae XK27_00720 ko:K13730 ko05100,map05100 ko00000,ko00001 Bacteria 1UVV3@1239,3F8E0@33958,4I2C6@91061,COG4886@1,COG4886@2 NA|NA|NA S Leucine-rich repeat (LRR) protein FFAGCILK_00319 543734.LCABL_06770 4.6e-177 627.1 Lactobacillaceae yicL Bacteria 1TR6G@1239,3F423@33958,4HAMD@91061,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family FFAGCILK_00320 543734.LCABL_06780 2.4e-311 1073.5 Lactobacillaceae Bacteria 1TPJG@1239,28HMX@1,2Z7WB@2,3F6T9@33958,4HBRI@91061 NA|NA|NA FFAGCILK_00321 543734.LCABL_06790 2.9e-145 521.2 Lactobacillaceae CcmA5 ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQIH@1239,3F5PG@33958,4HCT1@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter FFAGCILK_00322 543734.LCABL_06800 1.3e-88 332.4 Lactobacillaceae ko:K16923 M00582 ko00000,ko00002,ko02000 3.A.1.28 Bacteria 1V52B@1239,3FBCH@33958,4HJY9@91061,COG4720@1,COG4720@2 NA|NA|NA S ECF-type riboflavin transporter, S component FFAGCILK_00323 543734.LCABL_06810 3.8e-148 530.8 Lactobacillaceae pdxK 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TRCR@1239,3F3V7@33958,4HHME@91061,COG2240@1,COG2240@2 NA|NA|NA H Phosphomethylpyrimidine kinase FFAGCILK_00324 543734.LCABL_06820 5.2e-164 583.6 Lactobacillaceae metF GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 ko:K00297,ko:K21010 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,ko02025,map00670,map00720,map01100,map01120,map01200,map01523,map02025 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 iPC815.YPO0117,iSBO_1134.SBO_3961 Bacteria 1TQFE@1239,3FB7R@33958,4HGHI@91061,COG0685@1,COG0685@2 NA|NA|NA C Methylenetetrahydrofolate reductase FFAGCILK_00325 543734.LCABL_06830 0.0 1529.2 Lactobacillaceae metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0030312,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0040007,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0071944,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131 Bacteria 1TP2H@1239,3F3VW@33958,4H9QC@91061,COG0620@1,COG0620@2 NA|NA|NA E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation FFAGCILK_00326 543734.LCABL_06850 0.0 1092.8 Lactobacillaceae XK27_09600 ko:K06147,ko:K18891 ko02010,map02010 M00708 ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.109,3.A.1.135,3.A.1.21 Bacteria 1TP0B@1239,3F3SP@33958,4H9SC@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter, ATP-binding protein FFAGCILK_00327 543734.LCABL_06860 0.0 1144.8 Lactobacillaceae ko:K06147,ko:K18892 ko02010,map02010 M00708 ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.109,3.A.1.135,3.A.1.21 Bacteria 1TP0B@1239,3F3PD@33958,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter FFAGCILK_00328 543734.LCABL_06870 4.2e-223 780.4 Lactobacillaceae oxlT ko:K08177 ko00000,ko02000 2.A.1.11 Bacteria 1TPR9@1239,3F4XT@33958,4HB93@91061,COG2223@1,COG2223@2 NA|NA|NA P Major Facilitator Superfamily FFAGCILK_00329 543734.LCABL_06880 7.7e-129 466.5 Lactobacillaceae treR ko:K03486,ko:K03492,ko:K03710 ko00000,ko03000 Bacteria 1TRF6@1239,3F62J@33958,4HDCX@91061,COG2188@1,COG2188@2 NA|NA|NA K UTRA FFAGCILK_00330 543734.LCABL_06890 0.0 1136.7 Lactobacillaceae treC GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005991,GO:0005993,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008788,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0015927,GO:0016052,GO:0016787,GO:0016798,GO:0033554,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046352,GO:0050896,GO:0051716,GO:0071704,GO:1901575 3.2.1.93 ko:K01226 ko00500,map00500 R00837,R06113 RC00049 ko00000,ko00001,ko01000 GH13 iECW_1372.ECW_m4600,iEKO11_1354.EKO11_4072,iEcE24377_1341.EcE24377A_4811,iEcSMS35_1347.EcSMS35_4720,iWFL_1372.ECW_m4600 Bacteria 1TP53@1239,3F41I@33958,4HA1G@91061,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain protein FFAGCILK_00331 543734.LCABL_06900 0.0 1215.3 Lactobacillaceae treB 2.7.1.199,2.7.1.208,2.7.1.211 ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02790,ko:K02791,ko:K02809,ko:K02810 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00269,M00270,M00271,M00272,M00303,M00806 R00811,R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.3,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9 Bacteria 1TP5X@1239,3F458@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system FFAGCILK_00332 543734.LCABL_06910 3.6e-217 760.8 Lactobacillaceae sstT GO:0003333,GO:0003674,GO:0005215,GO:0005283,GO:0005295,GO:0005310,GO:0005342,GO:0005343,GO:0005416,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006820,GO:0006835,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015077,GO:0015081,GO:0015171,GO:0015175,GO:0015291,GO:0015293,GO:0015294,GO:0015318,GO:0015370,GO:0015672,GO:0015711,GO:0015804,GO:0015849,GO:0016020,GO:0016021,GO:0017153,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032329,GO:0034220,GO:0035725,GO:0044425,GO:0044464,GO:0046873,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1903825,GO:1905039 ko:K07862 ko00000,ko02000 2.A.23.4 iAF1260.b3089,iBWG_1329.BWG_2799,iECDH10B_1368.ECDH10B_3265,iECDH1ME8569_1439.ECDH1ME8569_2984,iECH74115_1262.ECH74115_4404,iECIAI1_1343.ECIAI1_3235,iECO103_1326.ECO103_3834,iECO111_1330.ECO111_3911,iECO26_1355.ECO26_4192,iECP_1309.ECP_3180,iECSE_1348.ECSE_3370,iECSP_1301.ECSP_4063,iECUMN_1333.ECUMN_3573,iECW_1372.ECW_m3356,iECs_1301.ECs3971,iEKO11_1354.EKO11_0630,iETEC_1333.ETEC_3359,iEcDH1_1363.EcDH1_0612,iEcE24377_1341.EcE24377A_3557,iG2583_1286.G2583_3813,iJO1366.b3089,iJR904.b3089,iSFV_1184.SFV_3130,iSSON_1240.SSON_3242,iUMNK88_1353.UMNK88_3845,iWFL_1372.ECW_m3356,iY75_1357.Y75_RS16050,iYL1228.KPN_03517,iZ_1308.Z4442 Bacteria 1TPD2@1239,3FB7N@33958,4HBEC@91061,COG3633@1,COG3633@2 NA|NA|NA U Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) FFAGCILK_00333 543734.LCABL_06920 1.9e-267 927.9 Lactobacillaceae yfnA ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ4K@1239,3F3QY@33958,4HA66@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino Acid FFAGCILK_00334 543734.LCABL_06930 3e-173 614.4 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1TPSY@1239,3F4MZ@33958,4HB0Z@91061,COG0039@1,COG0039@2 NA|NA|NA C lactate/malate dehydrogenase, alpha/beta C-terminal domain FFAGCILK_00335 543734.LCABL_06940 8.7e-251 872.5 Lactobacillaceae gdhA 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 R00248 RC00006,RC02799 ko00000,ko00001,ko01000 Bacteria 1TP45@1239,3F4DS@33958,4HAEI@91061,COG0334@1,COG0334@2 NA|NA|NA E Belongs to the Glu Leu Phe Val dehydrogenases family FFAGCILK_00336 1423732.BALS01000009_gene740 4.6e-31 139.8 Lactobacillaceae ko:K03704 ko00000,ko03000 Bacteria 1VEE0@1239,3F7RG@33958,4HNJC@91061,COG1278@1,COG1278@2 NA|NA|NA K 'Cold-shock' DNA-binding domain FFAGCILK_00337 543734.LCABL_06970 4.6e-68 263.8 Lactobacillaceae Bacteria 1U6ED@1239,29PCC@1,30AAK@2,3F7QE@33958,4IG65@91061 NA|NA|NA FFAGCILK_00338 543734.LCABL_06980 1.6e-76 292.0 Lactobacillaceae Bacteria 1VBJ0@1239,3F664@33958,4HNBY@91061,COG1764@1,COG1764@2 NA|NA|NA O OsmC-like protein FFAGCILK_00339 543734.LCABL_06990 1.9e-278 964.5 Lactobacillaceae lsa ko:K06158,ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000,ko03012 3.A.1.121 Bacteria 1TNYS@1239,3F53D@33958,4HBFK@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter FFAGCILK_00340 543734.LCABL_07000 2.3e-113 414.8 Lactobacillaceae ylbE Bacteria 1TQFS@1239,3F521@33958,4HDA2@91061,COG0702@1,COG0702@2 NA|NA|NA GM NAD(P)H-binding FFAGCILK_00342 543734.LCABL_07010 7.1e-158 563.1 Lactobacillaceae yeaE Bacteria 1VSK5@1239,3FBX5@33958,4HT3F@91061,COG0656@1,COG0656@2 NA|NA|NA S Aldo/keto reductase family FFAGCILK_00343 543734.LCABL_07020 2e-250 871.3 Lactobacillaceae yifK GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03293 ko00000 2.A.3.1 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease FFAGCILK_00344 543734.LCABL_07030 3.9e-256 891.0 Lactobacillaceae Bacteria 1U6PG@1239,29PJG@1,30AHM@2,3F896@33958,4IGGF@91061 NA|NA|NA S Protein of unknown function (DUF3800) FFAGCILK_00345 543734.LCABL_07040 0.0 1239.6 Lactobacillaceae yjcE GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 ko:K03316 ko00000 2.A.36 Bacteria 1TR4G@1239,3F42V@33958,4HBJR@91061,COG0025@1,COG0025@2 NA|NA|NA P Sodium proton antiporter FFAGCILK_00346 543734.LCABL_07050 9.6e-44 183.0 Lactobacillaceae Bacteria 1W5A8@1239,2C5CN@1,2ZGHZ@2,3F89I@33958,4I240@91061 NA|NA|NA S Protein of unknown function (DUF3021) FFAGCILK_00347 543734.LCABL_07060 1.7e-73 282.0 Lactobacillaceae Bacteria 1W04J@1239,3F6TA@33958,4HRMI@91061,COG3279@1,COG3279@2 NA|NA|NA K LytTr DNA-binding domain FFAGCILK_00348 543734.LCABL_07070 8.1e-149 533.1 Lactobacillaceae cylB ko:K11051 ko02010,map02010 M00298 ko00000,ko00001,ko00002,ko02000 3.A.1.130 Bacteria 1TSH0@1239,3FCET@33958,4HJK7@91061,COG0842@1,COG0842@2 NA|NA|NA V ABC-2 type transporter FFAGCILK_00349 543734.LCABL_07080 7e-164 583.2 Lactobacillaceae cylA ko:K01990,ko:K11050 ko02010,map02010 M00254,M00298 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.130 Bacteria 1TPJE@1239,3F58G@33958,4HB5U@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter FFAGCILK_00350 543734.LCABL_07090 3.7e-145 520.8 Lactobacillaceae Bacteria 1VXHZ@1239,3F75V@33958,4HX59@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha/beta hydrolase of unknown function (DUF915) FFAGCILK_00351 543734.LCABL_07100 4.2e-121 440.7 Lactobacillaceae cah 4.2.1.1 ko:K01674 ko00910,map00910 R00132,R10092 RC02807 ko00000,ko00001,ko01000 Bacteria 1V16J@1239,3F7DZ@33958,4HA62@91061,COG3338@1,COG3338@2 NA|NA|NA P Eukaryotic-type carbonic anhydrase FFAGCILK_00352 543734.LCABL_07110 2.6e-52 211.1 Lactobacillaceae ybjQ Bacteria 1VADM@1239,3F6YC@33958,4HKGZ@91061,COG0393@1,COG0393@2 NA|NA|NA S Belongs to the UPF0145 family FFAGCILK_00353 543734.LCABL_07120 6.9e-159 566.6 Lactobacillaceae 3.5.1.10 ko:K01433 ko00630,ko00670,map00630,map00670 R00944 RC00026,RC00111 ko00000,ko00001,ko01000 Bacteria 1TQ0M@1239,3F3WU@33958,4HA8M@91061,COG0604@1,COG0604@2 NA|NA|NA C nadph quinone reductase FFAGCILK_00354 543734.LCABL_07130 2.8e-246 857.4 Lactobacillaceae amt ko:K03320 ko00000,ko02000 1.A.11 Bacteria 1TQYG@1239,3F3X1@33958,4HBGK@91061,COG0004@1,COG0004@2 NA|NA|NA P ammonium transporter FFAGCILK_00355 543734.LCABL_07140 2.4e-178 631.3 Lactobacillaceae yfeX ko:K07223 ko00000 Bacteria 1UY9Y@1239,3F45Z@33958,4HACQ@91061,COG2837@1,COG2837@2 NA|NA|NA P Peroxidase FFAGCILK_00356 543734.LCABL_07150 4.3e-118 430.6 Lactobacillaceae yhiD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K07507 ko00000,ko02000 9.B.20 Bacteria 1V409@1239,3FB83@33958,4HHDI@91061,COG1285@1,COG1285@2 NA|NA|NA S MgtC family FFAGCILK_00357 543734.LCABL_07160 2.5e-115 421.8 Lactobacillaceae ko:K15051 ko00000 Bacteria 1V4X2@1239,3F3Y8@33958,4HIF5@91061,COG2169@1,COG2169@2 NA|NA|NA F DNA RNA non-specific endonuclease FFAGCILK_00359 768726.HMPREF9178_0015 9.8e-36 157.9 Streptococcus mitis ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1VB20@1239,2CKG7@1,2TNP2@28037,32SC9@2,4HMQX@91061 NA|NA|NA S ABC-2 family transporter protein FFAGCILK_00360 1423816.BACQ01000063_gene2437 2.1e-82 312.0 Lactobacillaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1VA12@1239,3F6Q1@33958,4HMB1@91061,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities FFAGCILK_00364 543734.LCABL_07180 0.0 1084.3 Lactobacillaceae ybiT GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0050896 ko:K06158 ko00000,ko03012 Bacteria 1TPW0@1239,3F3ZJ@33958,4HATH@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter, ATP-binding protein FFAGCILK_00365 543734.LCABL_07190 0.0 1080.5 Lactobacillaceae mutS ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1TPJP@1239,3F5Q9@33958,4HD9G@91061,COG0249@1,COG0249@2 NA|NA|NA L ATPase domain of DNA mismatch repair MUTS family FFAGCILK_00366 543734.LCABL_07200 4.2e-109 400.6 Lactobacillaceae ung2 3.2.2.27 ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1V1F8@1239,3F4WH@33958,4HFVS@91061,COG1573@1,COG1573@2 NA|NA|NA L Uracil-DNA glycosylase FFAGCILK_00367 543734.LCABL_07210 6.8e-130 469.9 Lactobacillaceae glpF ko:K02440 ko00000,ko02000 1.A.8.1,1.A.8.2 Bacteria 1TP4T@1239,3F4J6@33958,4HAWP@91061,COG0580@1,COG0580@2 NA|NA|NA U Belongs to the MIP aquaporin (TC 1.A.8) family FFAGCILK_00368 1423816.BACQ01000077_gene2626 3.2e-304 1050.4 Lactobacillaceae glpD 1.1.3.21,1.1.5.3 ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 R00846,R00848 RC00029 ko00000,ko00001,ko01000 Bacteria 1TQJN@1239,3F5BS@33958,4HAG8@91061,COG0578@1,COG0578@2 NA|NA|NA C C-terminal domain of alpha-glycerophosphate oxidase FFAGCILK_00369 543734.LCABL_07240 5e-295 1019.6 Lactobacillaceae glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 Bacteria 1TPX3@1239,3F3WI@33958,4H9ZF@91061,COG0554@1,COG0554@2 NA|NA|NA F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate FFAGCILK_00370 1423732.BALS01000046_gene2619 2e-143 515.0 Lactobacillaceae epsG 2.4.1.293 ko:K00786,ko:K17250 ko00000,ko01000,ko01003 GT2 Bacteria 1VVRP@1239,3FBSG@33958,4HGSR@91061,COG0463@1,COG0463@2 NA|NA|NA M Glycosyltransferase like family 2 FFAGCILK_00371 543734.LCABL_07260 1.4e-156 558.9 Lactobacillaceae lacT ko:K02531,ko:K02538,ko:K03488 ko00000,ko03000 Bacteria 1VS0S@1239,3F6AX@33958,4HTFM@91061,COG3711@1,COG3711@2 NA|NA|NA K PRD domain FFAGCILK_00372 543734.LCABL_07270 0.0 1098.2 Lactobacillaceae celB GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016310,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0071704 2.7.1.196,2.7.1.205,2.7.1.207 ko:K02760,ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 M00275,M00281 R04393,R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.1,4.A.3.2 Bacteria 1TQPV@1239,3F4DV@33958,4HC9I@91061,COG1440@1,COG1440@2,COG1455@1,COG1455@2 NA|NA|NA G Phosphotransferase system, EIIC FFAGCILK_00373 543734.LCABL_07280 2.7e-287 993.8 Lactobacillaceae lacG 3.2.1.85 ko:K01220 ko00052,ko01100,map00052,map01100 R03256 RC00049 ko00000,ko00001,ko01000 Bacteria 1TP19@1239,3FC7B@33958,4H9KU@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family FFAGCILK_00374 1423732.BALS01000046_gene2613 2.3e-51 208.0 Lactobacillaceae lacF 2.7.1.196,2.7.1.205,2.7.1.207 ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 M00275,M00281 R04393,R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.1,4.A.3.2 Bacteria 1V87W@1239,3FCDI@33958,4HJSY@91061,COG1447@1,COG1447@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIA subunit FFAGCILK_00375 543734.LCABL_07300 3.3e-222 777.3 Lactobacillaceae galK GO:0005975,GO:0005996,GO:0006012,GO:0008150,GO:0008152,GO:0019318,GO:0044238,GO:0044281,GO:0071704 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TPD0@1239,3F3Q9@33958,4HARP@91061,COG0153@1,COG0153@2 NA|NA|NA F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) FFAGCILK_00376 543734.LCABL_07310 3.6e-193 680.6 Lactobacillaceae galE 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ7N@1239,3F3YF@33958,4H9U5@91061,COG1087@1,COG1087@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family FFAGCILK_00377 543734.LCABL_07320 2.2e-279 967.6 Lactobacillaceae galT 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPBN@1239,3F4D8@33958,4HAYJ@91061,COG4468@1,COG4468@2 NA|NA|NA G UDP-glucose--hexose-1-phosphate uridylyltransferase FFAGCILK_00378 543734.LCABL_07330 1.1e-162 579.3 Lactobacillaceae ko:K02529 ko00000,ko03000 Bacteria 1TPZJ@1239,3F3PB@33958,4HC9Z@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator FFAGCILK_00379 543734.LCABL_07340 2.7e-196 691.0 Lactobacillaceae galM 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQGJ@1239,3F48R@33958,4HADZ@91061,COG2017@1,COG2017@2 NA|NA|NA G Catalyzes the interconversion of alpha and beta anomers of maltose FFAGCILK_00383 543734.LCABL_07380 7.2e-86 323.2 Lactobacillaceae 2.7.1.194,2.7.1.200,2.7.1.202,2.7.1.204 ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 M00273,M00279,M00283,M00306,M00550,M00807 R03232,R05570,R07671,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1,4.A.5,4.A.5.1,4.A.7.1 Bacteria 1VBW9@1239,3FBMU@33958,4IR84@91061,COG1762@1,COG1762@2 NA|NA|NA G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 FFAGCILK_00384 543734.LCABL_07390 1.4e-50 205.3 Lactobacillaceae 2.7.1.194,2.7.1.200,2.7.1.204 ko:K02774,ko:K02822,ko:K20113 ko00052,ko00053,ko01100,ko01120,ko02060,map00052,map00053,map01100,map01120,map02060 M00279,M00283,M00550,M00807 R05570,R07671,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5,4.A.5.1,4.A.7.1 Bacteria 1VACD@1239,3F732@33958,4HKHR@91061,COG3414@1,COG3414@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit FFAGCILK_00385 543734.LCABL_07400 7.2e-267 926.0 Lactobacillaceae gatC ko:K02775,ko:K20114 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279,M00807 R05570,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.5,4.A.5.1 Bacteria 1TQ10@1239,3FCCG@33958,4HBJG@91061,COG3775@1,COG3775@2 NA|NA|NA G PTS system sugar-specific permease component FFAGCILK_00386 543734.LCABL_07410 1.9e-26 124.4 Lactobacillaceae Bacteria 1U8CP@1239,29QNH@1,30BN4@2,3FAUA@33958,4IIAN@91061 NA|NA|NA FFAGCILK_00387 543734.LCABL_07420 4e-127 460.7 Lactobacillaceae Bacteria 1U95M@1239,28PTU@1,2ZCEZ@2,3F6AW@33958,4HMHN@91061 NA|NA|NA S Domain of unknown function (DUF4867) FFAGCILK_00388 543734.LCABL_07430 3.8e-176 624.0 Lactobacillaceae lacC 2.7.1.11,2.7.1.144,2.7.1.56 ko:K00882,ko:K00917,ko:K16370 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00345 R00756,R02071,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR9H@1239,3F56E@33958,4HAGR@91061,COG1105@1,COG1105@2 NA|NA|NA H pfkB family carbohydrate kinase FFAGCILK_00389 543734.LCABL_07440 5.6e-186 656.8 Lactobacillaceae yihT GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0034308,GO:0042180,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0061595,GO:0061720,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1901615,GO:1902776,GO:1902777 4.1.2.40,4.1.2.57 ko:K01635,ko:K01671 ko00052,ko01100,ko02024,map00052,map01100,map02024 R01069,R10760 RC00438,RC00439 ko00000,ko00001,ko01000 Bacteria 1TQRR@1239,3F3UA@33958,4HBS9@91061,COG3684@1,COG3684@2 NA|NA|NA G Belongs to the aldolase LacD family FFAGCILK_00390 543734.LCABL_07450 1.7e-93 348.6 Lactobacillaceae rpiB 2.1.1.222,2.1.1.64,5.3.1.26,5.3.1.6 ko:K00568,ko:K01808,ko:K01819 ko00030,ko00051,ko00052,ko00130,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00052,map00130,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00117,M00165,M00167 R01056,R03240,R04988,R05614,R08769,R08781,R09030 RC00003,RC00376,RC00392,RC00434,RC01895 ko00000,ko00001,ko00002,ko01000 Bacteria 1U9Y4@1239,3F41M@33958,4HE4C@91061,COG0698@1,COG0698@2 NA|NA|NA G Ribose/Galactose Isomerase FFAGCILK_00391 543734.LCABL_07460 2.7e-73 281.2 Lactobacillaceae lacA 5.3.1.26 ko:K01819 ko00052,ko01100,map00052,map01100 R03240 RC00376 ko00000,ko00001,ko01000 Bacteria 1V5VZ@1239,3F6CQ@33958,4HJK6@91061,COG0698@1,COG0698@2 NA|NA|NA G Ribose/Galactose Isomerase FFAGCILK_00392 543734.LCABL_07470 4.2e-141 507.3 Lactobacillaceae lacR ko:K02530 ko00000,ko03000 Bacteria 1V097@1239,3F5GM@33958,4HGA7@91061,COG1349@1,COG1349@2 NA|NA|NA K DeoR C terminal sensor domain FFAGCILK_00393 543734.LCABL_07480 3.8e-116 424.1 Lactobacillaceae gph 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 1V7U6@1239,3F658@33958,4HJ9I@91061,COG0546@1,COG0546@2 NA|NA|NA S HAD hydrolase, family IA, variant FFAGCILK_00394 543734.LCABL_07490 6.6e-212 743.0 Lactobacillaceae sbcD ko:K03547 ko00000,ko03400 Bacteria 1TQY6@1239,3F4A9@33958,4HAKB@91061,COG0420@1,COG0420@2 NA|NA|NA L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity FFAGCILK_00395 543734.LCABL_07500 0.0 1353.6 Lactobacillaceae sbcC ko:K03546 ko00000,ko03400 Bacteria 1TPCS@1239,3F3TE@33958,4H9Q3@91061,COG0419@1,COG0419@2 NA|NA|NA L Putative exonuclease SbcCD, C subunit FFAGCILK_00396 543734.LCABL_07510 2.1e-14 84.0 Lactobacillaceae Bacteria 1U74I@1239,29PWB@1,30AUN@2,3F8YT@33958,4IGZ5@91061 NA|NA|NA FFAGCILK_00397 543734.LCABL_07530 2.2e-76 291.6 Lactobacillaceae hsp1 ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 1VG0E@1239,3F7DR@33958,4HPDH@91061,COG0071@1,COG0071@2 NA|NA|NA O Belongs to the small heat shock protein (HSP20) family FFAGCILK_00399 543734.LCABL_07540 3.8e-212 743.8 Lactobacillaceae mutY ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPUT@1239,3FCD0@33958,4H9UM@91061,COG1194@1,COG1194@2 NA|NA|NA L A G-specific adenine glycosylase FFAGCILK_00400 543734.LCABL_07550 4.3e-149 533.9 Lactobacillaceae cytC6 Bacteria 1VEC5@1239,3F50A@33958,4HKY6@91061,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold FFAGCILK_00401 543734.LCABL_07560 3e-119 434.5 Lactobacillaceae yrkL ko:K11748 ko00000,ko02000 2.A.37.1.2 Bacteria 1V4UF@1239,3F6XY@33958,4HIR3@91061,COG2249@1,COG2249@2 NA|NA|NA S Flavodoxin-like fold FFAGCILK_00403 543734.LCABL_07580 1.5e-86 325.5 Lactobacillaceae Bacteria 1VK2X@1239,3F7G9@33958,4HQFY@91061,COG3247@1,COG3247@2 NA|NA|NA S Short repeat of unknown function (DUF308) FFAGCILK_00404 543734.LCABL_07590 4.1e-118 430.6 Lactobacillaceae Bacteria 1U5NN@1239,3F684@33958,4IFD7@91061,COG4832@1,COG4832@2 NA|NA|NA S Psort location Cytoplasmic, score FFAGCILK_00405 543734.LCABL_07600 4.6e-154 550.4 Lactobacillaceae thiD GO:0008150,GO:0040007 2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17 ko:K00941,ko:K03147,ko:K21219 ko00730,ko01100,map00730,map01100 M00127 R03223,R03471,R03472,R04509,R10712 RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ4A@1239,3F3NA@33958,4HAAH@91061,COG0351@1,COG0351@2 NA|NA|NA H Phosphomethylpyrimidine kinase FFAGCILK_00406 543734.LCABL_07610 2.8e-196 691.0 Lactobacillaceae Bacteria 1U7AN@1239,29Q0Q@1,30AZ6@2,3F980@33958,4IH5M@91061 NA|NA|NA FFAGCILK_00407 1423814.HMPREF0549_1693 3.9e-07 62.4 Lactobacillaceae Bacteria 1V8SY@1239,2AZ1J@1,31R7P@2,3F4MX@33958,4HJRD@91061 NA|NA|NA FFAGCILK_00408 543734.LCABL_07630 5.2e-116 423.7 Lactobacillaceae ywnB ko:K07118 ko00000 Bacteria 1TZ3T@1239,3F5K7@33958,4HVUN@91061,COG2910@1,COG2910@2 NA|NA|NA S NAD(P)H-binding FFAGCILK_00409 543734.LCABL_07640 0.0 1552.7 Lactobacillaceae bglB 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 GH3 Bacteria 1TP0T@1239,3F43A@33958,4HAAG@91061,COG1472@1,COG1472@2 NA|NA|NA G hydrolase, family 3 FFAGCILK_00410 543734.LCABL_07660 1.6e-166 592.0 Lactobacillaceae XK27_00670 ko:K01989,ko:K05832 M00247 ko00000,ko00002,ko02000 Bacteria 1TPB0@1239,3F4MI@33958,4HESK@91061,COG2984@1,COG2984@2 NA|NA|NA S ABC transporter substrate binding protein FFAGCILK_00411 543734.LCABL_07680 1.3e-163 582.4 Lactobacillaceae XK27_00670 ko:K01989,ko:K05832 M00247 ko00000,ko00002,ko02000 Bacteria 1TPB0@1239,3F462@33958,4HESK@91061,COG2984@1,COG2984@2 NA|NA|NA S ABC transporter FFAGCILK_00412 543734.LCABL_07690 1.8e-152 545.4 Lactobacillaceae WQ51_06230 ko:K01989,ko:K05832 M00247 ko00000,ko00002,ko02000 Bacteria 1TPDJ@1239,3F40J@33958,4HBMY@91061,COG4120@1,COG4120@2 NA|NA|NA U Belongs to the binding-protein-dependent transport system permease family FFAGCILK_00413 543734.LCABL_07700 8.8e-142 509.6 Lactobacillaceae cmpC ko:K05833 M00247 ko00000,ko00002,ko02000 Bacteria 1TPAN@1239,3F3NW@33958,4HCHC@91061,COG1101@1,COG1101@2 NA|NA|NA S ABC transporter, ATP-binding protein FFAGCILK_00414 543734.LCABL_07710 4.7e-174 617.1 Lactobacillaceae yhfP 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 1TPGR@1239,3F5R8@33958,4HACF@91061,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase FFAGCILK_00415 543734.LCABL_07720 0.0 1580.5 Lactobacillaceae pacL3 3.6.3.8 ko:K01537 ko00000,ko01000 3.A.3.2 Bacteria 1TPF5@1239,3F588@33958,4H9S5@91061,COG0474@1,COG0474@2 NA|NA|NA P Cation transporter/ATPase, N-terminus FFAGCILK_00416 543734.LCABL_07730 1.4e-181 642.1 Lactobacillaceae ykcC ko:K20534 ko00000,ko01000,ko01005,ko02000 4.D.2.1.9 GT2 Bacteria 1TPR3@1239,3F3X7@33958,4HC2Z@91061,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase family 2 FFAGCILK_00417 543734.LCABL_07740 0.0 1198.3 Lactobacillaceae ykcB Bacteria 1TPGI@1239,3F5B1@33958,4HCEY@91061,COG1807@1,COG1807@2 NA|NA|NA M Dolichyl-phosphate-mannose-protein mannosyltransferase FFAGCILK_00418 543734.LCABL_07750 6e-70 270.0 Lactobacillaceae Bacteria 1UIGW@1239,2DTIF@1,33KHD@2,3F7X1@33958,4ISGW@91061 NA|NA|NA S GtrA-like protein FFAGCILK_00419 543734.LCABL_07760 5.3e-124 450.3 Lactobacillaceae Bacteria 1V295@1239,3F3TH@33958,4HG3X@91061,COG0745@1,COG0745@2 NA|NA|NA K cheY-homologous receiver domain FFAGCILK_00420 543734.LCABL_07770 5.4e-242 843.2 Lactobacillaceae ciaH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K14982 ko02020,ko02024,map02020,map02024 M00521 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TS5K@1239,3F49T@33958,4H9Y1@91061,COG5002@1,COG5002@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain FFAGCILK_00421 543734.LCABL_07780 3.1e-68 264.2 Lactobacillaceae yqkB Bacteria 1VK6M@1239,3F7JD@33958,4HRFS@91061,COG4918@1,COG4918@2 NA|NA|NA S Belongs to the HesB IscA family FFAGCILK_00422 543734.LCABL_07790 3.7e-271 940.3 Lactobacillaceae Bacteria 1TRRH@1239,3F5KD@33958,4HQKK@91061,COG2508@1,COG2508@2 NA|NA|NA QT PucR C-terminal helix-turn-helix domain FFAGCILK_00423 543734.LCABL_07800 1.3e-162 578.9 Lactobacillaceae ptlF Bacteria 1UI5T@1239,3FBSB@33958,4HI5J@91061,COG4221@1,COG4221@2 NA|NA|NA S KR domain FFAGCILK_00424 543734.LCABL_07810 1.4e-158 565.5 Lactobacillaceae adc 4.1.1.4 ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 M00088 R01366 RC00040 ko00000,ko00001,ko00002,ko01000 Bacteria 1VW7Z@1239,3F5RQ@33958,4I17W@91061,COG4689@1,COG4689@2 NA|NA|NA Q Acetoacetate decarboxylase (ADC) FFAGCILK_00425 543734.LCABL_07820 3.5e-120 437.6 Lactobacillaceae drgA Bacteria 1UYJU@1239,3F4H1@33958,4HBVQ@91061,COG0778@1,COG0778@2 NA|NA|NA C Nitroreductase family FFAGCILK_00426 543734.LCABL_07830 3.5e-205 720.7 Lactobacillaceae lctO ko:K10530 ko00000,ko01000 Bacteria 1TPC4@1239,3F9FE@33958,4HAU5@91061,COG1304@1,COG1304@2 NA|NA|NA C IMP dehydrogenase / GMP reductase domain FFAGCILK_00429 543734.LCABL_07860 3.3e-189 667.5 Lactobacillaceae Bacteria 1V36C@1239,3F65G@33958,4IT3D@91061,COG1476@1,COG1476@2 NA|NA|NA K DNA-binding helix-turn-helix protein FFAGCILK_00430 543734.LCABL_07870 1.5e-58 231.9 Lactobacillaceae ko:K10947 ko00000,ko03000 Bacteria 1VA94@1239,3F6I1@33958,4HKJS@91061,COG1695@1,COG1695@2 NA|NA|NA K Transcriptional regulator PadR-like family FFAGCILK_00431 1423732.BALS01000001_gene1286 1.2e-41 175.6 Lactobacillaceae ygbF ko:K15383 ko00000,ko02000 9.A.58.2 Bacteria 1VBI9@1239,3F7IR@33958,4HMY5@91061,COG4095@1,COG4095@2 NA|NA|NA S Sugar efflux transporter for intercellular exchange FFAGCILK_00432 568703.LGG_00711 8.7e-42 176.0 Lactobacillaceae Bacteria 1U7Q2@1239,2AVVX@1,31MPR@2,3FA04@33958,4IHMD@91061 NA|NA|NA FFAGCILK_00433 543734.LCABL_07900 7e-192 676.4 Lactobacillaceae qor 1.1.1.1,1.6.5.5 ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 1TRNC@1239,3F48F@33958,4HATC@91061,COG0604@1,COG0604@2 NA|NA|NA C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily FFAGCILK_00435 543734.LCABL_07910 7e-54 216.5 Lactobacillaceae Bacteria 1U7KB@1239,2BQ7I@1,32J28@2,3F9V1@33958,4IHHD@91061 NA|NA|NA FFAGCILK_00436 543734.LCABL_07920 1.5e-80 305.4 Lactobacillaceae Bacteria 1U58T@1239,2CCJZ@1,303JM@2,3F565@33958,4IF00@91061 NA|NA|NA FFAGCILK_00437 543734.LCABL_07930 3.2e-209 734.2 Lactobacillaceae yubA Bacteria 1TQ84@1239,3F418@33958,4H9SR@91061,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter FFAGCILK_00438 568703.LGG_00716 3.1e-24 117.1 Lactobacillaceae Bacteria 1U7YK@1239,29QE7@1,30BDI@2,3FABT@33958,4IHVZ@91061 NA|NA|NA FFAGCILK_00439 543734.LCABL_07950 1.5e-112 412.1 Lactobacillaceae lexA 3.4.21.88 ko:K01356 M00729 ko00000,ko00002,ko01000,ko01002,ko03400 Bacteria 1TQ3H@1239,3F3JG@33958,4HBHA@91061,COG1974@1,COG1974@2 NA|NA|NA K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair FFAGCILK_00440 568703.LGG_00718 2.9e-44 184.9 Lactobacillaceae Bacteria 1U7KG@1239,29Q6R@1,30B5R@2,3F9VA@33958,4IHHI@91061 NA|NA|NA FFAGCILK_00441 543734.LCABL_07970 1.2e-166 593.2 Lactobacillaceae mleP2 ko:K07088 ko00000 Bacteria 1UY4N@1239,3FCFH@33958,4HB48@91061,COG0679@1,COG0679@2 NA|NA|NA S Transporter, auxin efflux carrier (AEC) family protein FFAGCILK_00442 1423732.BALS01000001_gene1300 1.2e-70 273.5 Lactobacillaceae Bacteria 1U7EG@1239,29Q3E@1,30B22@2,3F9H2@33958,4IHAC@91061 NA|NA|NA FFAGCILK_00443 543734.LCABL_08020 7.9e-97 359.8 Lactobacillaceae ygfA GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 R02301 RC00183 ko00000,ko00001,ko01000 iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298 Bacteria 1VA91@1239,3F4KQ@33958,4HM35@91061,COG0212@1,COG0212@2 NA|NA|NA H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family FFAGCILK_00444 543734.LCABL_08030 5.7e-61 240.0 Lactobacillaceae yeaO Bacteria 1VABH@1239,3F715@33958,4HKI2@91061,COG3189@1,COG3189@2 NA|NA|NA S Protein of unknown function, DUF488 FFAGCILK_00445 543734.LCABL_08040 1.3e-173 615.5 Lactobacillaceae corA ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria 1TPI8@1239,3F5FV@33958,4HE7S@91061,COG0598@1,COG0598@2 NA|NA|NA P CorA-like Mg2+ transporter protein FFAGCILK_00446 543734.LCABL_08050 1.4e-156 558.9 Lactobacillaceae mleR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 Bacteria 1V5VW@1239,3F5D2@33958,4HHDY@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR family FFAGCILK_00447 543734.LCABL_08060 0.0 1098.2 Lactobacillaceae sfcA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0030145,GO:0036094,GO:0043167,GO:0043169,GO:0043464,GO:0044237,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.1.1.38,4.1.1.101 ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 R00214,R11074 RC00105,RC00282 ko00000,ko00001,ko01000 Bacteria 1TPJ3@1239,3F3RH@33958,4HBF1@91061,COG0281@1,COG0281@2 NA|NA|NA C Malic enzyme FFAGCILK_00448 543734.LCABL_08070 3.2e-170 604.4 Lactobacillaceae mleP ko:K07088 ko00000 Bacteria 1UY4N@1239,3F3S0@33958,4HDX5@91061,COG0679@1,COG0679@2 NA|NA|NA S Sodium Bile acid symporter family FFAGCILK_00449 543734.LCABL_08080 1.4e-89 335.5 Lactobacillaceae tpx 1.11.1.15 ko:K11065 ko00000,ko01000 Bacteria 1V474@1239,3F5VY@33958,4HFMW@91061,COG2077@1,COG2077@2 NA|NA|NA O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides FFAGCILK_00450 543734.LCABL_08090 2.7e-85 321.2 Bacteria Bacteria COG0716@1,COG0716@2 NA|NA|NA C FMN binding FFAGCILK_00451 543734.LCABL_08100 1.7e-171 608.6 Lactobacillaceae Bacteria 1UZI0@1239,3F6R7@33958,4HC2C@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins FFAGCILK_00452 543734.LCABL_08110 1.1e-265 922.2 Lactobacillaceae Bacteria 1TSRV@1239,3F3JJ@33958,4HIAU@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region FFAGCILK_00453 543734.LCABL_08120 0.0 1208.7 Lactobacillaceae pepF Bacteria 1TR7D@1239,3F3R3@33958,4HA0P@91061,COG1164@1,COG1164@2 NA|NA|NA E Oligopeptidase F FFAGCILK_00454 543734.LCABL_08130 4.1e-59 233.8 Lactobacillaceae Bacteria 1U7MR@1239,29Q7J@1,30B6K@2,3F9X3@33958,4IHIY@91061 NA|NA|NA FFAGCILK_00455 543734.LCABL_08140 7.6e-132 476.5 Lactobacillaceae Bacteria 1V7U7@1239,3F491@33958,4HIUT@91061,COG1028@1,COG1028@2 NA|NA|NA IQ Belongs to the short-chain dehydrogenases reductases (SDR) family FFAGCILK_00456 543734.LCABL_08150 1.7e-81 308.5 Lactobacillaceae ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 Bacteria 1V44G@1239,3F68C@33958,4HH8C@91061,COG0105@1,COG0105@2 NA|NA|NA F Belongs to the NDK family FFAGCILK_00457 543734.LCABL_08160 0.0 1432.9 Lactobacillaceae yfgQ ko:K12952 ko00000,ko01000 3.A.3.23 Bacteria 1TPF5@1239,3F4Y1@33958,4H9ZI@91061,COG0474@1,COG0474@2 NA|NA|NA P E1-E2 ATPase FFAGCILK_00458 543734.LCABL_08170 2.1e-179 634.8 Bacteria 3.4.11.5 ko:K01259 ko00330,map00330 R00135 ko00000,ko00001,ko01000,ko01002 Bacteria COG2267@1,COG2267@2 NA|NA|NA I carboxylic ester hydrolase activity FFAGCILK_00459 568703.LGG_00737 2.6e-45 188.0 Lactobacillaceae Bacteria 1U7PN@1239,29Q8P@1,30B7R@2,3F9ZK@33958,4IHKZ@91061 NA|NA|NA FFAGCILK_00460 543734.LCABL_08190 2.6e-94 351.3 Lactobacillaceae cysE 2.3.1.178 ko:K06718 ko00260,ko01100,ko01120,map00260,map01100,map01120 M00033 R06978 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 Bacteria 1UM04@1239,3FBX6@33958,4ITN9@91061,COG1670@1,COG1670@2 NA|NA|NA J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins FFAGCILK_00461 543734.LCABL_08200 1.9e-198 698.4 Lactobacillaceae napA GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0009847,GO:0015075,GO:0015077,GO:0015081,GO:0015291,GO:0015297,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032502,GO:0034220,GO:0035725,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662 Bacteria 1TS32@1239,3F3QK@33958,4HAGC@91061,COG0475@1,COG0475@2 NA|NA|NA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family FFAGCILK_00462 543734.LCABL_08210 2.2e-122 444.9 Lactobacillaceae gph GO:0003674,GO:0003824,GO:0004672,GO:0004713,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0071704,GO:0140096,GO:1901564 3.1.3.18 ko:K01091,ko:K07025 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 1V1FQ@1239,3FCA0@33958,4HQUJ@91061,COG0546@1,COG0546@2 NA|NA|NA S haloacid dehalogenase-like hydrolase FFAGCILK_00463 543734.LCABL_08220 8.8e-78 296.2 Lactobacillaceae Bacteria 1V6TR@1239,3F66M@33958,4HXA8@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator FFAGCILK_00464 543734.LCABL_08230 9.5e-180 636.0 Lactobacillaceae ko:K06889 ko00000 Bacteria 1TQYU@1239,3F43H@33958,4HC4H@91061,COG1073@1,COG1073@2 NA|NA|NA D Alpha beta FFAGCILK_00465 543734.LCABL_08240 2.5e-83 314.7 Lactobacillaceae nrdI ko:K03647 ko00000 Bacteria 1V71V@1239,3F6JF@33958,4HIW7@91061,COG1780@1,COG1780@2 NA|NA|NA F Belongs to the NrdI family FFAGCILK_00466 543734.LCABL_08250 1.3e-156 558.9 Lactobacillaceae dkgB Bacteria 1TPM1@1239,3F4XF@33958,4HACK@91061,COG0656@1,COG0656@2 NA|NA|NA S reductase FFAGCILK_00467 543734.LCABL_08260 1e-155 556.2 Lactobacillaceae Bacteria 1U7BX@1239,29Q1I@1,30B03@2,3F9BB@33958,4IH77@91061 NA|NA|NA FFAGCILK_00468 543734.LCABL_08270 2.2e-143 515.0 Lactobacillaceae Bacteria 1VSYU@1239,3F4J2@33958,4HU15@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha beta hydrolase FFAGCILK_00469 543734.LCABL_08280 6.6e-119 433.3 Lactobacillaceae yviA Bacteria 1TPNF@1239,3F4F3@33958,4HF15@91061,COG2323@1,COG2323@2 NA|NA|NA S Protein of unknown function (DUF421) FFAGCILK_00470 543734.LCABL_08290 3.5e-74 284.3 Lactobacillaceae Bacteria 1VG8C@1239,2C9NT@1,32ZGB@2,3F749@33958,4HN0V@91061 NA|NA|NA S Protein of unknown function (DUF3290) FFAGCILK_00472 543734.LCABL_08300 2.1e-32 144.4 Lactobacillaceae yxjG 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPDQ@1239,3F49P@33958,4HADW@91061,COG0620@1,COG0620@2 NA|NA|NA E methionine synthase, vitamin-B12 independent FFAGCILK_00473 543734.LCABL_08300 1.7e-173 615.1 Lactobacillaceae yxjG 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPDQ@1239,3F49P@33958,4HADW@91061,COG0620@1,COG0620@2 NA|NA|NA E methionine synthase, vitamin-B12 independent FFAGCILK_00474 543734.LCABL_08310 2.2e-87 328.2 Lactobacillaceae luxS GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009116,GO:0009119,GO:0009372,GO:0009987,GO:0010699,GO:0016053,GO:0016829,GO:0016846,GO:0017144,GO:0019284,GO:0019752,GO:0023052,GO:0033353,GO:0034641,GO:0042278,GO:0043094,GO:0043102,GO:0043436,GO:0043768,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046128,GO:0046394,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0051704,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_2877,iPC815.YPO3300 Bacteria 1V1CH@1239,3F4W2@33958,4HFPR@91061,COG1854@1,COG1854@2 NA|NA|NA H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) FFAGCILK_00475 543734.LCABL_08320 3.2e-104 384.4 Lactobacillaceae yjbF Bacteria 1V7NH@1239,3FCEX@33958,4HJDU@91061,COG0398@1,COG0398@2 NA|NA|NA S SNARE associated Golgi protein FFAGCILK_00476 543734.LCABL_08330 1.3e-102 379.0 Lactobacillaceae ruvA GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1V3KF@1239,3F42W@33958,4HHI5@91061,COG0632@1,COG0632@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB FFAGCILK_00477 543734.LCABL_08340 3.2e-189 667.5 Lactobacillaceae ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TR47@1239,3F47S@33958,4HBMW@91061,COG2255@1,COG2255@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing FFAGCILK_00478 543734.LCABL_08350 1e-206 725.7 Lactobacillaceae queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 ko00000,ko01000,ko03016 Bacteria 1TPKD@1239,3F3VG@33958,4H9PT@91061,COG0809@1,COG0809@2 NA|NA|NA J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) FFAGCILK_00479 543734.LCABL_08360 8.8e-228 795.8 Lactobacillaceae tgt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 R03789,R10209 RC00063 ko00000,ko01000,ko03016 Bacteria 1TNZ4@1239,3F43F@33958,4HCNM@91061,COG0343@1,COG0343@2 NA|NA|NA F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) FFAGCILK_00480 543734.LCABL_08370 1.2e-65 255.8 Lactobacillaceae yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1VEMC@1239,3F7EY@33958,4HNK0@91061,COG1862@1,COG1862@2 NA|NA|NA U Preprotein translocase FFAGCILK_00481 543734.LCABL_08380 0.0 1707.6 Lactobacillaceae adhE 1.1.1.1,1.2.1.10 ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 Bacteria 1TPB4@1239,3F3RN@33958,4HAN8@91061,COG1012@1,COG1012@2,COG1454@1,COG1454@2 NA|NA|NA C belongs to the iron- containing alcohol dehydrogenase family FFAGCILK_00482 543734.LCABL_08390 2.3e-116 424.9 Lactobacillaceae sirR ko:K03709 ko00000,ko03000 Bacteria 1V4V7@1239,3FBMJ@33958,4HI7T@91061,COG1321@1,COG1321@2 NA|NA|NA K Helix-turn-helix diphteria tox regulatory element FFAGCILK_00483 543734.LCABL_08400 4.3e-291 1006.5 Lactobacillaceae zwf GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 iIT341.HP1101 Bacteria 1TPYF@1239,3F48G@33958,4HA73@91061,COG0364@1,COG0364@2 NA|NA|NA G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone FFAGCILK_00484 543734.LCABL_08410 5.5e-203 713.4 Lactobacillaceae dinB GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031668,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 ko:K02346 ko00000,ko01000,ko03400 Bacteria 1TP42@1239,3F44N@33958,4HADJ@91061,COG0389@1,COG0389@2 NA|NA|NA L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII FFAGCILK_00485 543734.LCABL_08420 2.3e-240 837.8 Lactobacillaceae ytoI Bacteria 1TPU6@1239,3F41P@33958,4HB62@91061,COG4109@1,COG4109@2 NA|NA|NA K DRTGG domain FFAGCILK_00486 543734.LCABL_08430 3.7e-179 634.0 Lactobacillaceae nrnA GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPXX@1239,3F4FC@33958,4H9ZW@91061,COG0618@1,COG0618@2 NA|NA|NA S DHHA1 domain protein FFAGCILK_00487 543734.LCABL_08440 1.9e-250 871.3 Lactobacillaceae cshB GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 1TPAP@1239,3F4FQ@33958,4HA98@91061,COG0513@1,COG0513@2 NA|NA|NA JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures FFAGCILK_00488 543734.LCABL_08450 8.6e-173 612.8 Lactobacillaceae Bacteria 1UJCK@1239,295Z0@1,2ZT9T@2,3F63F@33958,4IT5A@91061 NA|NA|NA FFAGCILK_00489 543734.LCABL_08460 0.0 1755.3 Lactobacillaceae alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPK6@1239,3F3QS@33958,4H9XC@91061,COG0013@1,COG0013@2 NA|NA|NA J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain FFAGCILK_00490 1423816.BACQ01000079_gene2741 2.7e-117 428.7 Lactobacillaceae Bacteria 1U65R@1239,29P5T@1,30A3Y@2,3F74N@33958,4IFVK@91061 NA|NA|NA FFAGCILK_00491 1423732.BALS01000001_gene1354 4e-43 180.3 Lactobacillaceae yrzL Bacteria 1VAC4@1239,3F7EG@33958,4HKD0@91061,COG4472@1,COG4472@2 NA|NA|NA S Belongs to the UPF0297 family FFAGCILK_00492 543734.LCABL_08480 1.6e-73 282.0 Lactobacillaceae yqgF GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K07447 ko00000,ko01000 Bacteria 1V6ER@1239,3F6NI@33958,4HH04@91061,COG0816@1,COG0816@2 NA|NA|NA J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA FFAGCILK_00493 543734.LCABL_08490 6.8e-53 213.0 Lactobacillaceae yrzB Bacteria 1VAPW@1239,3F6X3@33958,4HKV7@91061,COG3906@1,COG3906@2 NA|NA|NA S Belongs to the UPF0473 family FFAGCILK_00494 543734.LCABL_08500 5.8e-36 156.4 Lactobacillaceae zapA GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000921,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032185,GO:0032505,GO:0032506,GO:0034622,GO:0042802,GO:0043093,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051301,GO:0061640,GO:0065003,GO:0070925,GO:0071840,GO:0090529,GO:1902410,GO:1903047 ko:K09888 ko00000,ko03036 Bacteria 1VFZS@1239,3F7ZA@33958,4HP4T@91061,COG3027@1,COG3027@2 NA|NA|NA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division FFAGCILK_00495 543734.LCABL_08510 2.1e-91 341.7 Lactobacillaceae cvpA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 ko:K03558 ko00000 Bacteria 1V7U0@1239,3F6FV@33958,4HIUU@91061,COG1286@1,COG1286@2 NA|NA|NA S Colicin V production protein FFAGCILK_00496 543734.LCABL_08520 0.0 1496.5 Lactobacillaceae mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1TP5W@1239,3F4DX@33958,4H9NZ@91061,COG1193@1,COG1193@2 NA|NA|NA L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity FFAGCILK_00497 543734.LCABL_08530 6.6e-53 213.0 Lactobacillaceae trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 1VA3Y@1239,3F6Y3@33958,4HKKX@91061,COG3118@1,COG3118@2 NA|NA|NA O Belongs to the thioredoxin family FFAGCILK_00498 543734.LCABL_08540 6.1e-20 102.4 Lactobacillaceae dltX Bacteria 1U6XZ@1239,2DKST@1,30APB@2,3F8PK@33958,4IGS5@91061 NA|NA|NA S D-Ala-teichoic acid biosynthesis protein FFAGCILK_00499 543734.LCABL_08550 1.1e-294 1018.5 Lactobacillaceae dltA GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016208,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0022857,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1TPTH@1239,3F49R@33958,4HAHU@91061,COG1020@1,COG1020@2 NA|NA|NA H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall FFAGCILK_00500 543734.LCABL_08560 2.6e-238 830.9 Lactobacillaceae dltB ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 ko00000,ko00001,ko00002,ko01504 Bacteria 1TP52@1239,3F4KK@33958,4HBQG@91061,COG1696@1,COG1696@2 NA|NA|NA M MBOAT, membrane-bound O-acyltransferase family FFAGCILK_00501 543734.LCABL_08570 1.2e-36 158.7 Lactobacillaceae dltC GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K02078,ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1VFQI@1239,3F7Q1@33958,4HNIH@91061,COG0236@1,COG0236@2 NA|NA|NA J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall FFAGCILK_00502 543734.LCABL_08580 3.3e-244 850.5 Lactobacillaceae dltD ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 ko00000,ko00001,ko00002,ko01504 Bacteria 1TSZU@1239,3F3WE@33958,4HC3H@91061,COG3966@1,COG3966@2 NA|NA|NA M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) FFAGCILK_00503 543734.LCABL_08590 3.6e-85 320.9 Lactobacillaceae yslB Bacteria 1VD7N@1239,3F7ZI@33958,4HKV3@91061,COG1719@1,COG1719@2 NA|NA|NA S Protein of unknown function (DUF2507) FFAGCILK_00504 543734.LCABL_08600 2.9e-276 957.2 Lactobacillaceae murI GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009056,GO:0009058,GO:0009059,GO:0009141,GO:0009143,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016854,GO:0016855,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0030203,GO:0030234,GO:0032780,GO:0034404,GO:0034641,GO:0034645,GO:0034654,GO:0034655,GO:0036361,GO:0042030,GO:0042546,GO:0042802,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0055086,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2000371,GO:2000372 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 iYO844.BSU28390 Bacteria 1TPPR@1239,3F446@33958,4HA46@91061,COG0127@1,COG0127@2,COG0796@1,COG0796@2 NA|NA|NA M Provides the (R)-glutamate required for cell wall biosynthesis FFAGCILK_00505 543734.LCABL_08610 2.5e-97 361.3 Lactobacillaceae ko:K07095 ko00000 Bacteria 1VA0U@1239,3F73R@33958,4HM24@91061,COG0622@1,COG0622@2 NA|NA|NA S Phosphoesterase FFAGCILK_00506 543734.LCABL_08620 2.5e-135 488.0 Lactobacillaceae gla ko:K02440 ko00000,ko02000 1.A.8.1,1.A.8.2 Bacteria 1TP4T@1239,3FCCB@33958,4HE39@91061,COG0580@1,COG0580@2 NA|NA|NA U Major intrinsic protein FFAGCILK_00507 543734.LCABL_08630 2.1e-85 321.6 Lactobacillaceae ykuL Bacteria 1VFAB@1239,3FBMW@33958,4HRWJ@91061,COG0517@1,COG0517@2 NA|NA|NA S CBS domain FFAGCILK_00508 543734.LCABL_08640 6e-155 553.5 Lactobacillaceae XK27_00890 ko:K08974 ko00000 Bacteria 1UYD5@1239,3F4QH@33958,4HBE3@91061,COG2035@1,COG2035@2 NA|NA|NA S Domain of unknown function (DUF368) FFAGCILK_00509 543734.LCABL_08650 3.2e-153 547.7 Lactobacillaceae ykuT GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0042802,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 ko:K22044 ko00000,ko02000 1.A.23.3 Bacteria 1TR9Z@1239,3F49U@33958,4HCB8@91061,COG0668@1,COG0668@2 NA|NA|NA M mechanosensitive ion channel FFAGCILK_00510 543734.LCABL_08660 6e-12 77.4 Lactobacillaceae WQ51_05790 Bacteria 1VAXN@1239,3F6KB@33958,4HM93@91061,COG4768@1,COG4768@2 NA|NA|NA S protein containing a divergent version of the methyl-accepting chemotaxis-like domain FFAGCILK_00511 543734.LCABL_08670 1.2e-86 325.9 Lactobacillaceae ytxH Bacteria 1VFY7@1239,3F8GC@33958,4HNWV@91061,COG4980@1,COG4980@2 NA|NA|NA S YtxH-like protein FFAGCILK_00512 543734.LCABL_08680 5.1e-90 337.0 Lactobacillaceae niaR ko:K07105 ko00000 Bacteria 1V6EY@1239,3F7V1@33958,4HGYB@91061,COG1827@1,COG1827@2 NA|NA|NA S 3H domain FFAGCILK_00513 543734.LCABL_08690 2.8e-215 754.2 Lactobacillaceae pepQ 3.4.13.9 ko:K01271 ko00000,ko01000,ko01002 Bacteria 1TQ6R@1239,3F3X5@33958,4HA5I@91061,COG0006@1,COG0006@2 NA|NA|NA E Creatinase/Prolidase N-terminal domain FFAGCILK_00514 543734.LCABL_08700 6e-180 636.7 Lactobacillaceae ccpA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K02529 ko00000,ko03000 Bacteria 1TQ7K@1239,3F4AA@33958,4H9NG@91061,COG1609@1,COG1609@2 NA|NA|NA K catabolite control protein A FFAGCILK_00515 1423732.BALS01000001_gene1381 0.0 1469.9 Lactobacillaceae pbp1B 2.4.1.129,3.4.16.4 ko:K03693,ko:K05365,ko:K05366,ko:K05367,ko:K12551,ko:K21464 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 1TPM5@1239,3F4ZE@33958,4H9SA@91061,COG0744@1,COG0744@2 NA|NA|NA M Penicillin binding protein transpeptidase domain FFAGCILK_00516 543734.LCABL_08750 4e-127 460.7 Lactobacillaceae yjjG GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006206,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008655,GO:0009058,GO:0009112,GO:0009410,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019856,GO:0019859,GO:0030145,GO:0034641,GO:0034654,GO:0042221,GO:0042578,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.102,3.1.3.104,3.1.3.5,3.8.1.2 ko:K01560,ko:K07025,ko:K08723,ko:K20862 ko00230,ko00240,ko00361,ko00625,ko00740,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00740,map00760,map01100,map01110,map01120 M00125 R00183,R00511,R00548,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287,R07280 RC00017,RC00697 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_4614 Bacteria 1TRQ6@1239,3FBG9@33958,4HKAS@91061,COG1011@1,COG1011@2 NA|NA|NA S HAD-hyrolase-like FFAGCILK_00517 543734.LCABL_08760 6.1e-137 493.4 Lactobacillaceae birA 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 Bacteria 1TQCU@1239,3F5HY@33958,4HB60@91061,COG0340@1,COG0340@2 NA|NA|NA H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor FFAGCILK_00518 543734.LCABL_08770 3.8e-273 946.8 Lactobacillaceae pepV 3.5.1.18 ko:K01270,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 M00016 R00899,R02734,R04951 RC00064,RC00090,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TPEG@1239,3F3UV@33958,4HC14@91061,COG0624@1,COG0624@2 NA|NA|NA E dipeptidase PepV FFAGCILK_00519 543734.LCABL_08780 1.1e-258 898.7 Lactobacillaceae ugpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1UGF1@1239,3FC1S@33958,4H9QE@91061,COG0584@1,COG0584@2 NA|NA|NA C Glycerophosphoryl diester phosphodiesterase family FFAGCILK_00520 543734.LCABL_08790 2.7e-54 217.6 Lactobacillaceae Bacteria 1VX4A@1239,2C26E@1,3424N@2,3F70Q@33958,4HXT9@91061 NA|NA|NA FFAGCILK_00521 543734.LCABL_08810 2.2e-188 664.8 Lactobacillaceae yibE Bacteria 1TPEV@1239,3F3M9@33958,4HCP3@91061,COG5438@1,COG5438@2 NA|NA|NA S overlaps another CDS with the same product name FFAGCILK_00522 543734.LCABL_08820 1.4e-114 419.1 Lactobacillaceae yibF Bacteria 1TSWX@1239,3F3S6@33958,4HBKX@91061,COG5438@1,COG5438@2 NA|NA|NA S overlaps another CDS with the same product name FFAGCILK_00523 543734.LCABL_08830 4.5e-114 417.2 Lactobacillaceae Bacteria 1V40Y@1239,3F4EX@33958,4HH4J@91061,COG4186@1,COG4186@2 NA|NA|NA S Calcineurin-like phosphoesterase FFAGCILK_00524 543734.LCABL_08840 2.2e-265 921.0 Lactobacillaceae yunD 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 Bacteria 1TQCW@1239,3F4ZD@33958,4HAUC@91061,COG0737@1,COG0737@2 NA|NA|NA F Belongs to the 5'-nucleotidase family FFAGCILK_00525 543734.LCABL_08850 6e-117 426.8 Lactobacillaceae yutD Bacteria 1VA85@1239,3F66P@33958,4HKF7@91061,COG4470@1,COG4470@2 NA|NA|NA S Protein of unknown function (DUF1027) FFAGCILK_00526 543734.LCABL_08860 2.8e-145 521.2 Lactobacillaceae nagD 2.7.1.25,3.1.3.41 ko:K00860,ko:K01101 ko00230,ko00627,ko00920,ko01100,ko01120,map00230,map00627,map00920,map01100,map01120 M00176 R00509,R03024,R04928 RC00002,RC00078,RC00151 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQGM@1239,3F49D@33958,4HA3R@91061,COG0647@1,COG0647@2 NA|NA|NA G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro FFAGCILK_00527 543734.LCABL_08870 3.3e-112 411.0 Lactobacillaceae Bacteria 1V7UW@1239,3F4YP@33958,4HHH4@91061,COG4478@1,COG4478@2 NA|NA|NA S Protein of unknown function (DUF1461) FFAGCILK_00528 543734.LCABL_08880 5.2e-116 423.7 Lactobacillaceae dedA ko:K03975 ko00000 Bacteria 1UZ4P@1239,3F4KG@33958,4HG3F@91061,COG0586@1,COG0586@2 NA|NA|NA S SNARE-like domain protein FFAGCILK_00529 543734.LCABL_08890 6.7e-87 326.6 Lactobacillaceae pgpA 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 R02029 RC00017 ko00000,ko00001,ko01000 Bacteria 1V3I0@1239,3F6QT@33958,4HH4Y@91061,COG1267@1,COG1267@2 NA|NA|NA I Phosphatidylglycerophosphatase A FFAGCILK_00530 543734.LCABL_08900 7.9e-185 652.9 Lactobacillaceae trxB1 1.18.1.2,1.19.1.1 ko:K21567 ko00000,ko01000 Bacteria 1TRPN@1239,3F3NQ@33958,4H9V7@91061,COG0492@1,COG0492@2 NA|NA|NA C Ferredoxin--NADP reductase FFAGCILK_00531 543734.LCABL_08910 2.5e-109 401.4 Lactobacillaceae ppiB GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K01802,ko:K03768 ko00000,ko01000,ko03110 Bacteria 1TRHW@1239,3F3TI@33958,4H9V0@91061,COG0652@1,COG0652@2 NA|NA|NA G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides FFAGCILK_00532 543734.LCABL_08920 1.1e-62 245.7 Lactobacillaceae yugI 5.3.1.9 ko:K01810,ko:K02945,ko:K07570,ko:K07571,ko:K19142 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko03010,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map03010 M00001,M00004,M00114,M00178 R02739,R02740,R03321 RC00376,RC00563 br01610,ko00000,ko00001,ko00002,ko01000,ko02048,ko03011,ko04147 Bacteria 1VASQ@1239,3F6AN@33958,4HKSW@91061,COG1098@1,COG1098@2 NA|NA|NA J general stress protein FFAGCILK_00533 568703.LGG_00307 6.3e-19 99.0 Lactobacillaceae Bacteria 1VB4V@1239,2DX7X@1,32V2Y@2,3F76M@33958,4HKWS@91061 NA|NA|NA S COG NOG38524 non supervised orthologous group FFAGCILK_00534 1140001.I571_00001 4e-20 103.2 Firmicutes Bacteria 1VI2S@1239,2ED6K@1,3373A@2 NA|NA|NA S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts FFAGCILK_00535 638302.HMPREF0908_0610 6.6e-11 73.2 Firmicutes Bacteria 1VM14@1239,2EU6P@1,33MP7@2 NA|NA|NA FFAGCILK_00561 543734.LCABL_09250 2.1e-94 351.7 Bacteria sigH ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation FFAGCILK_00562 543734.LCABL_09260 3.8e-283 980.3 Lactobacillaceae ybeC Bacteria 1TPJH@1239,3F4AR@33958,4HC13@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid FFAGCILK_00563 543734.LCABL_09270 1.2e-230 805.4 Lactobacillaceae mgs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576 2.4.1.337 ko:K19002 ko00561,ko01100,map00561,map01100 R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 GT4 Bacteria 1TPTA@1239,3F4H5@33958,4HA41@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase, group 1 family protein FFAGCILK_00564 543734.LCABL_09280 5e-198 696.8 Lactobacillaceae cpoA GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901576 ko:K13678 R10865 RC00005,RC00049 ko00000,ko01000,ko01003 GT4 Bacteria 1TPSS@1239,3F47X@33958,4HB9F@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase, group 1 family protein FFAGCILK_00565 543734.LCABL_09290 1.9e-165 588.6 Lactobacillaceae mprF ko:K07027 ko00000,ko02000 4.D.2 Bacteria 1UY7Z@1239,3F3UR@33958,4HCG6@91061,COG0392@1,COG0392@2 NA|NA|NA I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms FFAGCILK_00567 543734.LCABL_09310 1.4e-217 761.9 Lactobacillaceae patA 2.6.1.1 ko:K00812,ko:K00841,ko:K10907 ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00525 R00355,R00694,R00734,R00896,R02433,R02619,R04467,R05052 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP0J@1239,3F3MX@33958,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase FFAGCILK_00568 543734.LCABL_09320 1.9e-43 181.4 Lactobacillaceae ykuJ Bacteria 1VKD0@1239,3F82V@33958,4HRGC@91061,COG4703@1,COG4703@2 NA|NA|NA S Protein of unknown function (DUF1797) FFAGCILK_00569 543734.LCABL_09330 0.0 1367.8 Lactobacillaceae ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 R05081,R10849 RC00017 ko00000,ko00001,ko01000 Bacteria 1TRMA@1239,3F3R7@33958,4H9S0@91061,COG1368@1,COG1368@2 NA|NA|NA M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily FFAGCILK_00570 543734.LCABL_09340 4e-80 303.9 Lactobacillaceae perR GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K03711,ko:K09825 ko00000,ko03000 Bacteria 1V400@1239,3F67J@33958,4HHF8@91061,COG0735@1,COG0735@2 NA|NA|NA P Belongs to the Fur family FFAGCILK_00571 543734.LCABL_20590 5.6e-223 780.0 Lactobacillaceae serS GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF987.Gmet_3528,iSDY_1059.SDY_2368 Bacteria 1TP4W@1239,3F3M6@33958,4H9Y4@91061,COG0172@1,COG0172@2 NA|NA|NA J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) FFAGCILK_00572 543734.LCABL_20600 1.7e-301 1041.2 Lactobacillaceae frvR GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 ko:K02538,ko:K03483,ko:K09685,ko:K18531 ko00000,ko03000 Bacteria 1VVKT@1239,3F5TE@33958,4HWA8@91061,COG3711@1,COG3711@2 NA|NA|NA K Mga helix-turn-helix domain FFAGCILK_00573 543734.LCABL_20610 1.2e-17 94.7 Lactobacillaceae frvR GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 ko:K02538,ko:K03483,ko:K09685,ko:K18531 ko00000,ko03000 Bacteria 1UVBC@1239,3F5V6@33958,4I2VB@91061,COG3711@1,COG3711@2 NA|NA|NA K Mga helix-turn-helix domain FFAGCILK_00574 543734.LCABL_20610 1.2e-263 915.2 Lactobacillaceae frvR GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 ko:K02538,ko:K03483,ko:K09685,ko:K18531 ko00000,ko03000 Bacteria 1UVBC@1239,3F5V6@33958,4I2VB@91061,COG3711@1,COG3711@2 NA|NA|NA K Mga helix-turn-helix domain FFAGCILK_00575 543734.LCABL_20620 3e-265 920.6 Lactobacillaceae lysP ko:K03293,ko:K11733 ko00000,ko02000 2.A.3.1,2.A.3.1.2 Bacteria 1UHNR@1239,3F4BG@33958,4HUT7@91061,COG0833@1,COG0833@2 NA|NA|NA E amino acid FFAGCILK_00577 543734.LCABL_20640 1.1e-130 472.6 Lactobacillaceae budA GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0047605 4.1.1.5 ko:K01575 ko00650,ko00660,map00650,map00660 R02948 RC00812 ko00000,ko00001,ko01000 Bacteria 1V4AH@1239,3FCCX@33958,4HJ98@91061,COG3527@1,COG3527@2 NA|NA|NA Q Alpha-acetolactate decarboxylase FFAGCILK_00578 543734.LCABL_20650 0.0 1105.1 Lactobacillaceae alsS 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQE8@1239,3FCE6@33958,4HAV1@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family FFAGCILK_00579 543734.LCABL_20660 2e-97 361.7 Lactobacillaceae Bacteria 1UG8K@1239,29V6R@1,30GKF@2,3F5MB@33958,4IF4K@91061 NA|NA|NA FFAGCILK_00580 543734.LCABL_20670 6e-99 366.7 Lactobacillaceae 2.3.1.128 ko:K03790 ko00000,ko01000,ko03009 Bacteria 1V49W@1239,3F5A6@33958,4HHAP@91061,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain FFAGCILK_00581 543734.LCABL_20680 1.7e-190 671.8 Bacteria Bacteria COG4072@1,COG4072@2 NA|NA|NA S Protein of unknown function C-terminal (DUF3324) FFAGCILK_00582 568703.LGG_01903 1.2e-87 329.3 Lactobacillaceae Bacteria 1U7HI@1239,2BIND@1,32CVF@2,3F9PY@33958,4IHE6@91061 NA|NA|NA FFAGCILK_00583 1423732.BALS01000021_gene323 2e-18 97.4 Bacilli rpmG GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02913 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VGZK@1239,4HSMA@91061,COG0267@1,COG0267@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL33 family FFAGCILK_00584 543734.LCABL_20710 4.9e-116 423.7 Lactobacillaceae sodA 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Bacteria 1TPXT@1239,3F6BJ@33958,4HA6U@91061,COG0605@1,COG0605@2 NA|NA|NA C Destroys radicals which are normally produced within the cells and which are toxic to biological systems FFAGCILK_00585 543734.LCABL_20720 2.2e-157 561.6 Lactobacillaceae rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 ko00000,ko01000,ko03009,ko03016 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 1TS1T@1239,3F46Z@33958,4HBRY@91061,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil FFAGCILK_00586 543734.LCABL_20730 1.3e-156 558.9 Lactobacillaceae Bacteria 1VEC5@1239,3F50A@33958,4HKY6@91061,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold FFAGCILK_00587 1423816.BACQ01000046_gene1709 2.6e-26 125.6 Lactobacillaceae Bacteria 1U7KZ@1239,2AIC8@1,318TE@2,3F9W0@33958,4IHI2@91061 NA|NA|NA FFAGCILK_00588 543734.LCABL_20750 9.3e-74 282.7 Lactobacillaceae Bacteria 1VKJ5@1239,2EIVY@1,33CM8@2,3F7QM@33958,4HRQ2@91061 NA|NA|NA FFAGCILK_00589 543734.LCABL_20760 6.2e-154 550.1 Lactobacillaceae citG 2.4.2.52,2.7.7.61 ko:K05966,ko:K13927,ko:K13930 ko02020,map02020 R09675,R10706 RC00049,RC00063 ko00000,ko00001,ko01000 Bacteria 1TQGQ@1239,3F4SU@33958,4HGCS@91061,COG1767@1,COG1767@2 NA|NA|NA H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase FFAGCILK_00590 543734.LCABL_20780 1.1e-124 452.6 Lactobacillaceae citR Bacteria 1TSV2@1239,3F532@33958,4HATG@91061,COG1802@1,COG1802@2 NA|NA|NA K FCD FFAGCILK_00591 543734.LCABL_20790 3.1e-267 927.2 Lactobacillaceae oadA 2.1.3.1,4.1.1.3,6.4.1.1,6.4.1.7 ko:K01571,ko:K01960,ko:K03416,ko:K20140 ko00020,ko00620,ko00640,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00640,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00217,R00344,R00353,R00930 RC00040,RC00097,RC00367 ko00000,ko00001,ko00002,ko01000,ko02000 3.B.1.1.1 iJN746.PP_5346,iLJ478.TM0128 Bacteria 1VT8P@1239,3F58W@33958,4HBJ1@91061,COG5016@1,COG5016@2 NA|NA|NA C Conserved carboxylase domain FFAGCILK_00592 543734.LCABL_20800 1.5e-92 345.5 Lactobacillaceae citX 2.4.2.52,2.7.7.61 ko:K05964,ko:K13927 ko02020,map02020 R09675,R10706 RC00049,RC00063 ko00000,ko00001,ko01000 Bacteria 1VB3E@1239,3F74S@33958,4HMZ5@91061,COG3697@1,COG3697@2 NA|NA|NA HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase FFAGCILK_00593 543734.LCABL_20810 5.9e-288 996.1 Lactobacillaceae citF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.8.3.10 ko:K01643 ko02020,map02020 R00362 RC00067,RC01118 ko00000,ko00001,ko01000 iEcSMS35_1347.EcSMS35_0634 Bacteria 1TPN3@1239,3F4EA@33958,4HAE1@91061,COG3051@1,COG3051@2 NA|NA|NA H Citrate (pro-3S)-lyase alpha chain FFAGCILK_00594 543734.LCABL_20820 9e-156 556.2 Lactobacillaceae citE 4.1.3.25,4.1.3.34 ko:K01644,ko:K18292 ko00660,ko01100,ko02020,map00660,map01100,map02020 R00237,R00362 RC00067,RC00502,RC01118,RC01205 ko00000,ko00001,ko01000 Bacteria 1TPDY@1239,3F47Q@33958,4HD40@91061,COG2301@1,COG2301@2 NA|NA|NA G Belongs to the HpcH HpaI aldolase family FFAGCILK_00595 543734.LCABL_20830 1.3e-48 198.7 Lactobacillaceae citD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0008815,GO:0009346,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016833,GO:0032991,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 ko:K01646 ko02020,map02020 R00362 RC00067,RC01118 ko00000,ko00001 Bacteria 1VEZZ@1239,3F7FR@33958,4HNXD@91061,COG3052@1,COG3052@2 NA|NA|NA C Covalent carrier of the coenzyme of citrate lyase FFAGCILK_00596 543734.LCABL_20840 1.5e-178 632.1 Lactobacillaceae citC 6.2.1.22 ko:K01910 ko02020,map02020 R04449 RC00012,RC00039 ko00000,ko00001,ko01000 Bacteria 1TSGQ@1239,3F4H7@33958,4HC6Q@91061,COG3053@1,COG3053@2 NA|NA|NA H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase FFAGCILK_00598 543734.LCABL_20860 1.8e-196 691.8 Lactobacillaceae oadB 4.1.1.3 ko:K01572 ko00620,ko01100,map00620,map01100 R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 Bacteria 1TPEP@1239,3F61X@33958,4HEF4@91061,COG1883@1,COG1883@2 NA|NA|NA C Na+-transporting oxaloacetate decarboxylase beta subunit FFAGCILK_00599 543734.LCABL_20870 1.8e-39 168.7 Lactobacillaceae gcdC 2.3.1.12 ko:K00627,ko:K02160 ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00307,M00376 R00209,R00742,R02569 RC00004,RC00040,RC00367,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1VW7S@1239,3F7V3@33958,4HJSW@91061,COG0511@1,COG0511@2 NA|NA|NA I Biotin-requiring enzyme FFAGCILK_00600 543734.LCABL_20880 5.9e-52 209.9 Lactobacillaceae Bacteria 1W0WF@1239,2EDVU@1,337QZ@2,3F8EE@33958,4HZEA@91061 NA|NA|NA FFAGCILK_00601 543734.LCABL_20890 1.1e-240 839.0 Lactobacillaceae citM ko:K03300 ko00000 2.A.11 Bacteria 1TQQH@1239,3F5EB@33958,4HAGT@91061,COG2851@1,COG2851@2 NA|NA|NA C Citrate transporter FFAGCILK_00602 543734.LCABL_20900 2.8e-41 174.1 Lactobacillaceae Bacteria 1VPIM@1239,2ENWC@1,33GHC@2,3F826@33958,4HRIM@91061 NA|NA|NA FFAGCILK_00603 543734.LCABL_20910 3.3e-103 380.9 Lactobacillaceae kptA ko:K07559 ko00000,ko01000,ko03016 Bacteria 1V49Y@1239,3FBCQ@33958,4HHHZ@91061,COG1859@1,COG1859@2 NA|NA|NA J Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase FFAGCILK_00604 543734.LCABL_20920 5.5e-86 323.6 Lactobacillaceae ko:K03830 ko00000,ko01000 Bacteria 1V6S5@1239,3F6HM@33958,4HJJY@91061,COG0454@1,COG0456@2 NA|NA|NA K GNAT family FFAGCILK_00605 543734.LCABL_20930 1.3e-105 389.0 Lactobacillaceae 1.5.1.40 ko:K06988 ko00000,ko01000 Bacteria 1V35D@1239,3F5EP@33958,4HFSW@91061,COG2085@1,COG2085@2 NA|NA|NA S NADP oxidoreductase coenzyme F420-dependent FFAGCILK_00606 543734.LCABL_20940 9.7e-58 229.2 Lactobacillaceae ko:K10947 ko00000,ko03000 Bacteria 1VAGB@1239,3F70B@33958,4HKBS@91061,COG1695@1,COG1695@2 NA|NA|NA K Transcriptional regulator PadR-like family FFAGCILK_00607 543734.LCABL_20950 5.4e-150 537.0 Lactobacillaceae ORF00048 Bacteria 1V9IF@1239,3F6UB@33958,4HKB8@91061,COG4858@1,COG4858@2 NA|NA|NA FFAGCILK_00608 543734.LCABL_20960 8.1e-137 493.0 Lactobacillaceae nfrA 1.5.1.38,1.5.1.39 ko:K19285,ko:K19286 ko00740,ko01100,map00740,map01100 R05705,R05706 RC00126 ko00000,ko00001,ko01000 Bacteria 1UB8S@1239,3F4IY@33958,4HEGP@91061,COG0778@1,COG0778@2 NA|NA|NA C nitroreductase FFAGCILK_00609 748671.LCRIS_00536 2.6e-169 601.3 Lactobacillaceae yjjC ko:K01990,ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQHS@1239,3F4JT@33958,4HC34@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter FFAGCILK_00610 748671.LCRIS_00537 3.2e-292 1010.4 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPIG@1239,3F4PV@33958,4H9SK@91061,COG3559@1,COG3559@2 NA|NA|NA M Exporter of polyketide antibiotics FFAGCILK_00611 543734.LCABL_20990 1.1e-113 416.0 Lactobacillaceae ko:K09017 ko00000,ko03000 Bacteria 1VG1F@1239,3F6KD@33958,4HPER@91061,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator FFAGCILK_00612 543734.LCABL_21000 1.5e-256 891.7 Lactobacillaceae ko:K18926 M00715 ko00000,ko00002,ko02000 2.A.1.3.30 Bacteria 1UYQB@1239,3F3NG@33958,4HE3Y@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily FFAGCILK_00613 543734.LCABL_21010 3.8e-126 457.6 Lactobacillaceae ko:K07090 ko00000 Bacteria 1V75K@1239,3F6BU@33958,4HEE8@91061,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein FFAGCILK_00614 543734.LCABL_21020 6.2e-156 557.0 Bacilli ko:K15256 ko00000,ko01000,ko03016 Bacteria 1V7TA@1239,4HWM9@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins FFAGCILK_00615 543734.LCABL_21030 3e-156 557.8 Lactobacillaceae Bacteria 1VSYU@1239,3F4J2@33958,4HU15@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha beta hydrolase FFAGCILK_00616 543734.LCABL_21040 5.2e-60 236.9 Lactobacillaceae yvoA_1 ko:K07979 ko00000,ko03000 Bacteria 1VA2B@1239,3F6GC@33958,4HPK4@91061,COG1725@1,COG1725@2 NA|NA|NA K Transcriptional regulator, GntR family FFAGCILK_00617 543734.LCABL_21050 1.5e-124 452.2 Lactobacillaceae skfE ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPUP@1239,3FC3Q@33958,4HC2V@91061,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities FFAGCILK_00618 913848.AELK01000184_gene664 6.7e-19 101.3 Lactobacillaceae Bacteria 1U5IX@1239,29NT4@1,309R6@2,3F624@33958,4HZ1H@91061 NA|NA|NA FFAGCILK_00619 1158607.UAU_01174 6.2e-143 514.2 Enterococcaceae Bacteria 1VSYT@1239,2EYF6@1,33RP4@2,4B49Z@81852,4HVCU@91061 NA|NA|NA FFAGCILK_00620 1158607.UAU_01175 1.1e-87 329.7 Enterococcaceae ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1VU5E@1239,4B2U2@81852,4HV26@91061,COG1136@1,COG1136@2 NA|NA|NA V ATPases associated with a variety of cellular activities FFAGCILK_00621 543734.LCABL_21070 1.9e-95 355.1 Lactobacillaceae ydaF ko:K03817 ko00000,ko01000,ko03009 Bacteria 1V3NE@1239,3F6YW@33958,4HG1N@91061,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain FFAGCILK_00622 543734.LCABL_21080 1.5e-158 565.5 Bacilli oppF ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1V36J@1239,4HUP0@91061,COG4608@1,COG4608@2 NA|NA|NA P Oligopeptide/dipeptide transporter, C-terminal region FFAGCILK_00623 543734.LCABL_21090 1.3e-199 702.2 Bacilli oppD ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1VRIF@1239,4HV11@91061,COG0444@1,COG0444@2 NA|NA|NA P Oligopeptide/dipeptide transporter, C-terminal region FFAGCILK_00624 1423816.BACQ01000047_gene1743 1.2e-22 112.5 Lactobacillaceae Bacteria 1U7RZ@1239,2AHSP@1,31856@2,3FA3D@33958,4IHPB@91061 NA|NA|NA FFAGCILK_00625 543734.LCABL_21110 1.5e-175 622.1 Bacilli amiD ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TP4R@1239,4HBB9@91061,COG1173@1,COG1173@2 NA|NA|NA EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components FFAGCILK_00626 543734.LCABL_21120 9.4e-167 592.8 Bacilli oppB ko:K02033,ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TP1S@1239,4HU8D@91061,COG0601@1,COG0601@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component FFAGCILK_00627 543734.LCABL_21130 7.1e-290 1002.7 Bacilli ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TNYQ@1239,4HTMF@91061,COG4166@1,COG4166@2 NA|NA|NA E Bacterial extracellular solute-binding proteins, family 5 Middle FFAGCILK_00628 543734.LCABL_21140 4.7e-128 463.8 Lactobacillaceae hchA Bacteria 1UG8E@1239,3F4SD@33958,4HCBM@91061,COG0693@1,COG0693@2 NA|NA|NA S DJ-1/PfpI family FFAGCILK_00629 543734.LCABL_21150 4.6e-52 210.3 Lactobacillaceae ko:K03892 ko00000,ko03000 Bacteria 1V6Z2@1239,3F7CV@33958,4HKFB@91061,COG0640@1,COG0640@2 NA|NA|NA K Transcriptional FFAGCILK_00630 543734.LCABL_21160 1.1e-35 155.6 Lactobacillaceae Bacteria 1W6HR@1239,28QAQ@1,2ZCTB@2,3F7NS@33958,4I0FP@91061 NA|NA|NA FFAGCILK_00631 543734.LCABL_21170 1.5e-260 905.2 Lactobacillaceae ko:K06147,ko:K06148 ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1UVV5@1239,3F9E9@33958,4I2V1@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region FFAGCILK_00632 543734.LCABL_21180 4e-287 993.4 Lactobacillaceae ko:K06147,ko:K06148,ko:K18889 ko02010,map02010 M00707 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,3F4HU@33958,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region FFAGCILK_00634 543734.LCABL_21200 3.2e-68 264.2 Lactobacillaceae Bacteria 1U5KS@1239,2F916@1,309SE@2,3F65Y@33958,4IFBR@91061 NA|NA|NA S Iron-sulphur cluster biosynthesis FFAGCILK_00635 1423816.BACQ01000047_gene1752 1.4e-15 89.0 Lactobacillaceae 2.7.1.39 ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1VG1G@1239,2DQV2@1,338VR@2,3F9IH@33958,4HQEQ@91061 NA|NA|NA S Phosphotransferase enzyme family FFAGCILK_00636 568703.LGG_01953 4.3e-244 851.7 Lactobacillaceae lytN 3.5.1.104 ko:K15125,ko:K17733,ko:K21449,ko:K22278 ko05133,map05133 ko00000,ko00001,ko00536,ko01000,ko01002,ko01011,ko02000 1.B.40.2 Bacteria 1VQJH@1239,3F4H3@33958,4HSU2@91061,COG1388@1,COG1388@2 NA|NA|NA M LysM domain FFAGCILK_00637 543734.LCABL_21230 1.4e-133 482.3 Lactobacillaceae zmp3 Bacteria 1V6X9@1239,3F6QI@33958,4HK8S@91061,COG5549@1,COG5549@2 NA|NA|NA O Zinc-dependent metalloprotease FFAGCILK_00638 543734.LCABL_21250 4.1e-128 464.2 Lactobacillaceae repA ko:K02444,ko:K03436 ko00000,ko03000 Bacteria 1UYQX@1239,3F6Z8@33958,4HMB5@91061,COG1349@1,COG1349@2 NA|NA|NA K DeoR C terminal sensor domain FFAGCILK_00640 543734.LCABL_21270 3.1e-48 197.6 Lactobacillaceae lciIC Bacteria 1TVRG@1239,2DCPK@1,2ZEV0@2,3FA25@33958,4I3X9@91061 NA|NA|NA K Helix-turn-helix XRE-family like proteins FFAGCILK_00641 290512.Paes_2314 8.4e-89 334.0 Chlorobi dcm 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Bacteria 1FF7V@1090,COG0270@1,COG0270@2 NA|NA|NA H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family FFAGCILK_00642 1121007.AUML01000037_gene2025 3.8e-82 312.8 Flavobacteriia ko:K06926 ko00000 Bacteria 1I7WT@117743,4PFP9@976,COG1106@1,COG1106@2 NA|NA|NA S AAA ATPase domain FFAGCILK_00644 1133569.AHYZ01000154_gene2213 4.4e-98 364.0 Lactobacillaceae Bacteria 1TQSK@1239,3FBC6@33958,4HGQX@91061,COG5340@1,COG5340@2 NA|NA|NA K Transcriptional regulator, AbiEi antitoxin FFAGCILK_00648 1138822.PL11_10130 2.3e-20 104.0 Lactobacillaceae Bacteria 1UN9D@1239,3FBZ4@33958,4IU8A@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix domain FFAGCILK_00650 1138822.PL11_10135 8.7e-57 226.1 Lactobacillaceae GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0045926,GO:0045927,GO:0046483,GO:0048518,GO:0048519,GO:0050789,GO:0050896,GO:0065007,GO:0070482,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 Bacteria 1VB8K@1239,3F7HF@33958,4HKT7@91061,COG4679@1,COG4679@2 NA|NA|NA S Phage derived protein Gp49-like (DUF891) FFAGCILK_00651 1138822.PL11_10140 1.9e-134 485.3 Bacilli Bacteria 1V8P5@1239,2B7B4@1,320E7@2,4HSR0@91061 NA|NA|NA FFAGCILK_00652 1138822.PL11_10145 1.1e-190 672.5 Bacilli ko:K03694,ko:K03696 ko01100,map01100 ko00000,ko03110 Bacteria 1UZ7G@1239,4HJBJ@91061,COG0542@1,COG0542@2 NA|NA|NA O AAA domain (Cdc48 subfamily) FFAGCILK_00653 543734.LCABL_21540 1.6e-304 1051.2 Lactobacillaceae guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.3.1.128,6.3.5.2 ko:K01951,ko:K03790 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002,ko03009 iLJ478.TM1820 Bacteria 1TPG8@1239,3F3NV@33958,4HA7Q@91061,COG0519@1,COG0519@2 NA|NA|NA F Catalyzes the synthesis of GMP from XMP FFAGCILK_00654 543734.LCABL_21550 3e-178 630.9 Lactobacillaceae coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iECDH1ME8569_1439.ECDH1ME8569_3838,iECH74115_1262.ECH74115_5439,iECSE_1348.ECSE_4265,iECSF_1327.ECSF_3833,iECSP_1301.ECSP_5045,iECW_1372.ECW_m4332,iEcDH1_1363.EcDH1_4016,iEcolC_1368.EcolC_4046,iPC815.YPO3758,iSFV_1184.SFV_4047,iSFxv_1172.SFxv_4418,iWFL_1372.ECW_m4332,iZ_1308.Z5545 Bacteria 1TPHJ@1239,3F42Q@33958,4HA4K@91061,COG1072@1,COG1072@2 NA|NA|NA F Pantothenic acid kinase FFAGCILK_00655 1423816.BACQ01000047_gene1773 2.7e-13 81.6 Lactobacillaceae Bacteria 1U8GV@1239,2BU50@1,32PDW@2,3FAYY@33958,4IIEQ@91061 NA|NA|NA FFAGCILK_00656 568703.LGG_01971 3.5e-24 117.5 Lactobacillaceae Bacteria 1U84D@1239,2AHIU@1,317WG@2,3FAIH@33958,4II1U@91061 NA|NA|NA FFAGCILK_00657 543734.LCABL_21580 8.2e-276 955.7 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase FFAGCILK_00658 543734.LCABL_21590 3.8e-84 317.4 Lactobacillaceae ykhA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 3.1.2.20 ko:K01073 ko00000,ko01000 Bacteria 1V3S2@1239,3F6A3@33958,4HJ0Z@91061,COG1607@1,COG1607@2 NA|NA|NA I Thioesterase superfamily FFAGCILK_00659 543734.LCABL_21600 0.0 1477.2 Lactobacillaceae helD 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TP39@1239,3F486@33958,4H9Y5@91061,COG3973@1,COG3973@2 NA|NA|NA L DNA helicase FFAGCILK_00660 568703.LGG_01977 2.5e-21 107.5 Lactobacillaceae Bacteria 1U818@1239,2AX78@1,31P5Y@2,3FAEP@33958,4IHYP@91061 NA|NA|NA FFAGCILK_00661 543734.LCABL_21610 0.0 1152.9 Lactobacillaceae yjbQ ko:K03455,ko:K03499 ko00000,ko02000 2.A.37,2.A.38.1,2.A.38.4 Bacteria 1TS32@1239,3F4AZ@33958,4H9Q5@91061,COG0475@1,COG0475@2,COG0569@1,COG0569@2 NA|NA|NA P TrkA C-terminal domain protein FFAGCILK_00662 543734.LCABL_21620 1.1e-180 639.0 Lactobacillaceae pip 3.4.11.5 ko:K01259 ko00330,map00330 R00135 ko00000,ko00001,ko01000,ko01002 Bacteria 1UEDT@1239,3F47H@33958,4HF61@91061,COG2267@1,COG2267@2 NA|NA|NA E Releases the N-terminal proline from various substrates FFAGCILK_00663 543734.LCABL_21630 1.3e-81 308.9 Lactobacillaceae yjhE Bacteria 1TQD1@1239,2C3KP@1,2Z802@2,3F71P@33958,4HBGA@91061 NA|NA|NA S Phage tail protein FFAGCILK_00664 543734.LCABL_21640 1.7e-241 841.6 Lactobacillaceae mntH GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 ko:K03322 ko00000,ko02000 2.A.55.2.6,2.A.55.3 Bacteria 1TPT1@1239,3F49Y@33958,4HAEA@91061,COG1914@1,COG1914@2 NA|NA|NA P H( )-stimulated, divalent metal cation uptake system FFAGCILK_00665 543734.LCABL_21650 4.4e-188 663.7 Lactobacillaceae hemH GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPKF@1239,3F4VU@33958,4HAYG@91061,COG0276@1,COG0276@2 NA|NA|NA H Catalyzes the ferrous insertion into protoporphyrin IX FFAGCILK_00666 543734.LCABL_21660 3.5e-128 464.2 Lactobacillaceae pgm3 Bacteria 1TQWQ@1239,3F524@33958,4HF2N@91061,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family FFAGCILK_00667 543734.LCABL_21670 0.0 1109.0 Lactobacillaceae ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TR2D@1239,3F45H@33958,4HAZG@91061,COG0577@1,COG0577@2 NA|NA|NA V FtsX-like permease family FFAGCILK_00668 543734.LCABL_21680 2.6e-135 488.0 Lactobacillaceae cysA ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TNZG@1239,3F3MG@33958,4H9UT@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein FFAGCILK_00669 543734.LCABL_21690 0.0 1091.3 Lactobacillaceae ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 1VTQI@1239,3FBET@33958,4HU7Y@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid FFAGCILK_00670 543734.LCABL_21700 5.8e-163 580.1 Lactobacillaceae yegS GO:0001727,GO:0003674,GO:0003824,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0030258,GO:0044237,GO:0044238,GO:0044255,GO:0046834,GO:0071704 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 R02240 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1V4PN@1239,3F3Z6@33958,4HHJP@91061,COG1597@1,COG1597@2 NA|NA|NA I Diacylglycerol kinase catalytic domain FFAGCILK_00671 543734.LCABL_21730 2.1e-238 831.2 Lactobacillaceae hflX ko:K03665 ko00000,ko03009 Bacteria 1TNZB@1239,3F4B2@33958,4HACA@91061,COG2262@1,COG2262@2 NA|NA|NA S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis FFAGCILK_00672 543734.LCABL_21740 8.9e-133 479.9 Lactobacillaceae nodB3 Bacteria 1TYRH@1239,3FC25@33958,4HHQN@91061,COG0726@1,COG0726@2 NA|NA|NA G Polysaccharide deacetylase FFAGCILK_00673 1158609.I586_01734 3.5e-31 142.5 Enterococcaceae Bacteria 1V90B@1239,4B4VR@81852,4HNI8@91061,COG3274@1,COG3274@2 NA|NA|NA S Acyltransferase family FFAGCILK_00674 1408226.T233_01038 9.9e-63 248.8 Enterococcaceae 3.2.1.96 ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Bacteria 1UNZW@1239,4B60V@81852,4IUVQ@91061,COG0791@1,COG0791@2 NA|NA|NA M NLP P60 protein FFAGCILK_00675 565655.ECBG_02869 3.7e-117 429.1 Enterococcaceae Bacteria 1VRSE@1239,4B22J@81852,4HI01@91061,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 FFAGCILK_00676 1158607.UAU_04639 7.3e-59 235.0 Enterococcaceae licD4 ko:K07271 ko00000,ko01000 Bacteria 1VANV@1239,4B1Y1@81852,4IPYQ@91061,COG3307@1,COG3307@2 NA|NA|NA M O-Antigen ligase FFAGCILK_00677 1158607.UAU_04640 7.5e-80 304.3 Enterococcaceae lsgC Bacteria 1TPHK@1239,4B3BW@81852,4HAXV@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 FFAGCILK_00678 1158607.UAU_04641 3.5e-150 538.5 Enterococcaceae cps2I Bacteria 1TR1W@1239,4B4J4@81852,4HCW6@91061,COG2244@1,COG2244@2 NA|NA|NA S Psort location CytoplasmicMembrane, score FFAGCILK_00679 1260356.D920_01305 1.7e-99 369.4 Enterococcaceae Bacteria 1VATJ@1239,4B1HJ@81852,4HCW0@91061,COG1216@1,COG1216@2 NA|NA|NA M group 2 family protein FFAGCILK_00680 543734.LCABL_12610 1e-121 443.4 Lactobacillaceae eps4I Bacteria 1TS59@1239,3F6WH@33958,4HC1B@91061,COG0451@1,COG0451@2 NA|NA|NA GM Male sterility protein FFAGCILK_00681 1158604.I591_01353 9.3e-103 379.8 Enterococcaceae ispD GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 1.1.1.405,2.7.7.40,2.7.7.60,4.6.1.12 ko:K00991,ko:K12506,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 M00096 R01525,R02921,R05633,R05637 RC00002,RC00089,RC01440 ko00000,ko00001,ko00002,ko01000 Bacteria 1TS1B@1239,4AZAT@81852,4HHZZ@91061,COG1211@1,COG1211@2 NA|NA|NA I 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase FFAGCILK_00682 565664.EFXG_02140 6.9e-116 423.7 Enterococcaceae licD3 ko:K07271 ko00000,ko01000 Bacteria 1TT6A@1239,4B0MD@81852,4HE2E@91061,COG3475@1,COG3475@2 NA|NA|NA M LicD family FFAGCILK_00683 1140002.I570_02161 3.5e-85 321.6 Enterococcaceae lsgF Bacteria 1V1CB@1239,4B0ZP@81852,4HHH7@91061,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family 2 FFAGCILK_00684 1423732.BALS01000012_gene1488 4.4e-197 694.1 Lactobacillaceae wcaJ ko:K03606 ko05111,map05111 ko00000,ko00001 Bacteria 1TP7M@1239,3F5WM@33958,4HB15@91061,COG2148@1,COG2148@2 NA|NA|NA M Bacterial sugar transferase FFAGCILK_00686 565653.EGBG_01762 4.8e-75 289.7 Enterococcaceae Bacteria 1UM6R@1239,4AZUX@81852,4ITS2@91061,COG1376@1,COG1376@2 NA|NA|NA S ErfK ybiS ycfS ynhG family protein FFAGCILK_00687 1201292.DR75_1485 2e-54 220.3 Enterococcaceae Bacteria 1VAQX@1239,2DQSR@1,338EM@2,4B4C5@81852,4HM5B@91061 NA|NA|NA FFAGCILK_00688 543734.LCABL_21850 2e-148 531.9 Lactobacillaceae cps2D 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS00780 Bacteria 1V34Y@1239,3F5GY@33958,4HCJE@91061,COG0451@1,COG0451@2 NA|NA|NA M RmlD substrate binding domain FFAGCILK_00689 543734.LCABL_21860 7.4e-110 403.3 Lactobacillaceae glnP GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 ko:K02029,ko:K10002,ko:K10040 ko02010,ko02020,map02010,map02020 M00228,M00230,M00236 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.19,3.A.1.3.4 Bacteria 1UJM4@1239,3F3WJ@33958,4HBAS@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter permease FFAGCILK_00690 543734.LCABL_21870 1e-108 399.4 Lactobacillaceae gluC GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 ko:K10006,ko:K10040 ko02010,map02010 M00228,M00233 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.9 Bacteria 1TQ5K@1239,3F3XW@33958,4HFBH@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter permease FFAGCILK_00691 543734.LCABL_21880 1.1e-147 529.3 Lactobacillaceae glnH ko:K10039 ko02010,map02010 M00228 ko00000,ko00001,ko00002,ko02000 3.A.1.3 Bacteria 1TT11@1239,3F4GG@33958,4HAHV@91061,COG0834@1,COG0834@2 NA|NA|NA ET ABC transporter substrate-binding protein FFAGCILK_00692 543734.LCABL_21890 7.4e-135 486.5 Lactobacillaceae glnQ 3.6.3.21 ko:K02028,ko:K10041 ko02010,map02010 M00228,M00236 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1TNYD@1239,3F3QQ@33958,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein FFAGCILK_00693 543734.LCABL_21900 4.7e-177 627.1 Lactobacillaceae Bacteria 1V7ET@1239,2C6F0@1,32RH8@2,3F4UC@33958,4HJDI@91061 NA|NA|NA FFAGCILK_00695 543734.LCABL_21920 6.1e-84 316.6 Lactobacillaceae zur GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K02076,ko:K03711 ko00000,ko03000 Bacteria 1V6RI@1239,3F6W3@33958,4HIGM@91061,COG0735@1,COG0735@2 NA|NA|NA P Belongs to the Fur family FFAGCILK_00696 543734.LCABL_21930 2.2e-09 67.0 Lactobacillaceae Bacteria 1U8CS@1239,29QNJ@1,30BN7@2,3FAUD@33958,4IIAR@91061 NA|NA|NA FFAGCILK_00697 543734.LCABL_21940 1e-110 406.0 Lactobacillaceae gmk2 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1V8PW@1239,3F6N3@33958,4HJCB@91061,COG0194@1,COG0194@2 NA|NA|NA F Guanylate kinase FFAGCILK_00698 543734.LCABL_21950 1.2e-67 262.3 Lactobacillaceae GnaT 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHQS@1239,3FBVW@33958,4IT2E@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain FFAGCILK_00699 543734.LCABL_21960 2.5e-124 452.2 Lactobacillaceae spl ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1UVYK@1239,3F5PQ@33958,4HDAX@91061,COG0791@1,COG0791@2 NA|NA|NA M NlpC/P60 family FFAGCILK_00700 543734.LCABL_21970 1.2e-244 852.0 Lactobacillaceae tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 iAF1260.b1637,iBWG_1329.BWG_1452,iECDH10B_1368.ECDH10B_1771,iECDH1ME8569_1439.ECDH1ME8569_1581,iECH74115_1262.ECH74115_2349,iECIAI39_1322.ECIAI39_1418,iECNA114_1301.ECNA114_1685,iECO103_1326.ECO103_1778,iECO111_1330.ECO111_2107,iECO26_1355.ECO26_2366,iECSE_1348.ECSE_1760,iECSF_1327.ECSF_1500,iECSP_1301.ECSP_2202,iECUMN_1333.ECUMN_1928,iECW_1372.ECW_m1805,iECs_1301.ECs2346,iEKO11_1354.EKO11_2137,iETEC_1333.ETEC_1672,iEcDH1_1363.EcDH1_2003,iEcE24377_1341.EcE24377A_1847,iEcHS_1320.EcHS_A1713,iEcSMS35_1347.EcSMS35_1562,iEcolC_1368.EcolC_1992,iJO1366.b1637,iSFV_1184.SFV_1654,iSF_1195.SF1662,iSSON_1240.SSON_1519,iSbBS512_1146.SbBS512_E1829,iUMNK88_1353.UMNK88_2097,iWFL_1372.ECW_m1805,iY75_1357.Y75_RS08585 Bacteria 1TPGN@1239,3F48J@33958,4H9YV@91061,COG0162@1,COG0162@2 NA|NA|NA J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) FFAGCILK_00701 543734.LCABL_21980 3.3e-172 610.9 Bacilli yeaB Bacteria 1TSGY@1239,4H9WP@91061,COG0053@1,COG0053@2 NA|NA|NA P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family FFAGCILK_00702 543734.LCABL_21990 1e-54 219.2 Lactobacillaceae arsR ko:K03892 ko00000,ko03000 Bacteria 1VFY4@1239,3F8JS@33958,4HP5T@91061,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor FFAGCILK_00703 543734.LCABL_22000 4.6e-174 617.1 Lactobacillaceae 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria 1TR9C@1239,3F3QR@33958,4HHVC@91061,COG1477@1,COG1477@2 NA|NA|NA H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein FFAGCILK_00704 543734.LCABL_22010 0.0 1232.2 Lactobacillaceae malQ 2.4.1.25,3.2.1.20,3.2.1.41 ko:K00705,ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 R00028,R00801,R00802,R02111,R05196,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 CBM48,GH13,GH31,GH77 Bacteria 1TNZ0@1239,3F41N@33958,4HB67@91061,COG0366@1,COG0366@2 NA|NA|NA G Belongs to the glycosyl hydrolase 13 family FFAGCILK_00705 543734.LCABL_22020 0.0 1609.3 Lactobacillaceae glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 R02111 ko00000,ko00001,ko01000 GT35 iYO844.BSU30940 Bacteria 1TQAJ@1239,3F4Z1@33958,4H9XI@91061,COG0058@1,COG0058@2 NA|NA|NA G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties FFAGCILK_00706 543734.LCABL_22030 8.9e-286 988.8 Lactobacillaceae glgA GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 GT5 Bacteria 1TQ4M@1239,3F3PP@33958,4HAVA@91061,COG0297@1,COG0297@2 NA|NA|NA F Synthesizes alpha-1,4-glucan chains using ADP-glucose FFAGCILK_00707 543734.LCABL_22040 9.4e-201 706.1 Lactobacillaceae glgD 2.4.1.21,2.7.7.27 ko:K00703,ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948,R02421 RC00002,RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 GT5 Bacteria 1TPZ3@1239,3F58E@33958,4H9UQ@91061,COG0448@1,COG0448@2 NA|NA|NA G Nucleotidyl transferase FFAGCILK_00708 543734.LCABL_22050 3.6e-197 694.1 Lactobacillaceae glgC 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TNZW@1239,3F4IA@33958,4HAZX@91061,COG0448@1,COG0448@2 NA|NA|NA H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans FFAGCILK_00709 543734.LCABL_22060 0.0 1493.0 Lactobacillaceae glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033554,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0071944,GO:1901576 2.4.1.18,3.2.1.141,3.2.1.20 ko:K00700,ko:K01187,ko:K01236,ko:K17734 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 M00565 R00028,R00801,R00802,R02110,R06087,R06088,R09995,R11256 RC00028,RC00049,RC00077 ko00000,ko00001,ko00002,ko01000,ko01002,ko04147 CBM48,GH13,GH31 iAPECO1_1312.APECO1_3025,iECNA114_1301.ECNA114_3542,iECOK1_1307.ECOK1_3857,iECS88_1305.ECS88_3830,iECSF_1327.ECSF_3253,iJN678.glgB,iLF82_1304.LF82_0837,iNRG857_1313.NRG857_17030,iUTI89_1310.UTI89_C3941 Bacteria 1TP4M@1239,3F4KT@33958,4HAPM@91061,COG0296@1,COG0296@2 NA|NA|NA G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position FFAGCILK_00710 543734.LCABL_22070 4.7e-204 716.8 Lactobacillaceae ilvE 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TQQI@1239,3F4BD@33958,4HASX@91061,COG0115@1,COG0115@2 NA|NA|NA E Branched-chain amino acid aminotransferase FFAGCILK_00711 543734.LCABL_22080 2e-102 379.0 Lactobacillaceae ylcC 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria 1VXZD@1239,3F9NX@33958,4HXV4@91061,COG3764@1,COG3764@2 NA|NA|NA M Sortase family FFAGCILK_00712 1423816.BACQ01000047_gene1785 6.3e-159 567.4 Lactobacillaceae Bacteria 1VE2G@1239,3F6FB@33958,4HMDI@91061,COG4990@1,COG4990@2 NA|NA|NA M Peptidase_C39 like family FFAGCILK_00713 543734.LCABL_22090 1.4e-145 522.3 Lactobacillaceae Bacteria 1TWZ5@1239,3F54A@33958,4HD8R@91061,COG1284@1,COG1284@2 NA|NA|NA S Uncharacterised 5xTM membrane BCR, YitT family COG1284 FFAGCILK_00714 543734.LCABL_22100 0.0 1304.3 Lactobacillaceae fbp 3.1.3.11 ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00165,M00167 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPFU@1239,3F4MG@33958,4HBAN@91061,COG3855@1,COG3855@2 NA|NA|NA G phosphatase activity FFAGCILK_00715 543734.LCABL_22110 2.6e-65 254.6 Lactobacillaceae nrp 1.20.4.1 ko:K00537,ko:K16509 ko00000,ko01000 Bacteria 1V3QC@1239,3F9SP@33958,4HH0I@91061,COG1393@1,COG1393@2 NA|NA|NA P ArsC family FFAGCILK_00716 543734.LCABL_22120 0.0 1380.5 Lactobacillaceae clpL ko:K04086 ko00000,ko03110 Bacteria 1TPMU@1239,3F43D@33958,4HA0V@91061,COG0542@1,COG0542@2 NA|NA|NA O associated with various cellular activities FFAGCILK_00717 543734.LCABL_22130 1.1e-144 519.2 Lactobacillaceae ywqE 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1TQ1T@1239,3F3RT@33958,4HDZR@91061,COG4464@1,COG4464@2 NA|NA|NA GM PHP domain protein FFAGCILK_00718 543734.LCABL_22140 5.2e-151 540.4 Lactobacillaceae brpA Bacteria 1TR1B@1239,3F3MQ@33958,4HA09@91061,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-like function transcriptional attenuator common domain protein FFAGCILK_00719 1423816.BACQ01000050_gene1844 1.2e-75 289.7 Lactobacillaceae cpsE Bacteria 1TP7M@1239,3F51J@33958,4HCBG@91061,COG2148@1,COG2148@2 NA|NA|NA M Bacterial sugar transferase FFAGCILK_00720 518635.BIFANG_03648 3e-46 192.6 Bifidobacteriales 1.13.11.79 ko:K04719 ko00740,ko01100,map00740,map01100 R09083 RC00435,RC02413 ko00000,ko00001,ko01000 Bacteria 2IE9H@201174,4CZI3@85004,COG0778@1,COG0778@2 NA|NA|NA C Psort location Cytoplasmic, score 8.87 FFAGCILK_00721 1140002.I570_02702 1.4e-111 410.2 Bacilli Bacteria 1TQ51@1239,4HEUP@91061,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein FFAGCILK_00722 1448857.JFAP01000002_gene1493 5.3e-32 145.2 Epsilonproteobacteria cpsJ Bacteria 1N72Z@1224,2YT9F@29547,42VSW@68525,COG1216@1,COG1216@2 NA|NA|NA S Glycosyltransferase like family 2 FFAGCILK_00723 1423780.LOT_2240 9.1e-92 344.0 Lactobacillaceae Bacteria 1TRCM@1239,3F6H1@33958,4HC0S@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 FFAGCILK_00724 714313.LSA_01590 4.2e-15 89.4 Lactobacillaceae Bacteria 1VE48@1239,2DTRN@1,32UVS@2,3FAVM@33958,4IIBV@91061 NA|NA|NA S EpsG family FFAGCILK_00725 1243664.CAVL020000006_gene4968 4.3e-29 135.6 Bacillus Bacteria 1VVRP@1239,1ZS2C@1386,4HVYS@91061,COG0463@1,COG0463@2 NA|NA|NA M Glycosyltransferase like family 2 FFAGCILK_00726 655812.HMPREF0061_0330 1.3e-42 180.6 Bacilli Bacteria 1UIAW@1239,4ITQ2@91061,COG1143@1,COG1143@2 NA|NA|NA C Polysaccharide pyruvyl transferase FFAGCILK_00727 1423780.LOT_2243 7.4e-107 394.0 Lactobacillaceae Bacteria 1TSXN@1239,3F5M7@33958,4IPQN@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferase 4-like FFAGCILK_00728 568703.LGG_02052 2e-103 382.1 Lactobacillaceae ywqD 2.7.10.1 ko:K08252,ko:K16554 ko05111,map05111 ko00000,ko00001,ko01000,ko02000 8.A.3.1 Bacteria 1TS4R@1239,3F4BM@33958,4HCEN@91061,COG0489@1,COG0489@2 NA|NA|NA D Capsular exopolysaccharide family FFAGCILK_00729 568703.LGG_02053 5e-125 454.1 Lactobacillaceae epsB Bacteria 1UZCR@1239,3F4M5@33958,4HE26@91061,COG3944@1,COG3944@2 NA|NA|NA M biosynthesis protein FFAGCILK_00730 525309.HMPREF0494_2165 3.1e-131 474.9 Lactobacillaceae rfbB 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPWM@1239,3F3R6@33958,4HA3Y@91061,COG1088@1,COG1088@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily FFAGCILK_00731 543734.LCABL_22360 2.8e-131 474.6 Lactobacillaceae Bacteria 1UI5G@1239,3F652@33958,4ISEF@91061,COG2755@1,COG2755@2 NA|NA|NA E lipolytic protein G-D-S-L family FFAGCILK_00732 543734.LCABL_22370 1.4e-81 308.9 Lactobacillaceae ccl GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1V22G@1239,3F6CG@33958,4HGG2@91061,COG4708@1,COG4708@2 NA|NA|NA S QueT transporter FFAGCILK_00733 543734.LCABL_22380 6.3e-123 446.8 Lactobacillaceae Bacteria 1U8IC@1239,3F4X3@33958,4HC26@91061,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase FFAGCILK_00734 543734.LCABL_22390 3.7e-37 160.2 Lactobacillaceae XK27_01315 Bacteria 1VFBF@1239,2E68Y@1,330X0@2,3F810@33958,4HP3V@91061 NA|NA|NA S Protein of unknown function (DUF2829) FFAGCILK_00735 543734.LCABL_22400 1.9e-47 194.9 Bacteria Bacteria COG1396@1,COG1396@2 NA|NA|NA K sequence-specific DNA binding FFAGCILK_00736 543734.LCABL_22410 3e-116 424.5 Lactobacillaceae gpm5 3.1.3.3,5.4.2.11 ko:K01834,ko:K22305 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R00582,R01518 RC00017,RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1V6ES@1239,3F4IS@33958,4HGZI@91061,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family FFAGCILK_00737 543734.LCABL_22420 6.5e-179 633.3 Lactobacillaceae oppF ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1V36J@1239,3F4GM@33958,4H9YB@91061,COG4608@1,COG4608@2 NA|NA|NA P Belongs to the ABC transporter superfamily FFAGCILK_00738 543734.LCABL_22430 2.5e-197 694.5 Lactobacillaceae oppD ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TP6E@1239,3F41T@33958,4HA4E@91061,COG0444@1,COG0444@2 NA|NA|NA P Belongs to the ABC transporter superfamily FFAGCILK_00739 543734.LCABL_22440 2.5e-178 631.3 Lactobacillaceae oppC ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TP4R@1239,3F3W3@33958,4H9PZ@91061,COG1173@1,COG1173@2 NA|NA|NA EP ABC-type dipeptide oligopeptide nickel transport systems, permease components FFAGCILK_00740 543734.LCABL_22450 8e-163 579.7 Lactobacillaceae oppB ko:K02033,ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TP1S@1239,3F42T@33958,4HA2S@91061,COG0601@1,COG0601@2 NA|NA|NA P ABC-type dipeptide oligopeptide nickel transport systems, permease components FFAGCILK_00741 543734.LCABL_22460 5.9e-302 1042.7 Lactobacillaceae oppA ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TNYQ@1239,3F3JE@33958,4HAMK@91061,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter, substratebinding protein FFAGCILK_00742 543734.LCABL_22470 9.9e-253 879.0 Lactobacillaceae Bacteria 1VSAB@1239,3FCCN@33958,4HECQ@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily FFAGCILK_00743 543734.LCABL_22490 1.3e-99 369.0 Lactobacillaceae efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02356 ko00000,ko03012 Bacteria 1TR8P@1239,3F4EW@33958,4H9YX@91061,COG0231@1,COG0231@2 NA|NA|NA J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase FFAGCILK_00744 543734.LCABL_22500 2.1e-131 474.9 Lactobacillaceae yrjD ko:K00782 ko00000 Bacteria 1UZAK@1239,3F4UV@33958,4HH3R@91061,COG1556@1,COG1556@2 NA|NA|NA S LUD domain FFAGCILK_00745 543734.LCABL_22510 3.1e-289 1000.3 Lactobacillaceae lutB ko:K18929 ko00000 iSF_1195.SF0259,iSFxv_1172.SFxv_0274,iS_1188.S0280 Bacteria 1TREQ@1239,3F4IV@33958,4H9UI@91061,COG1139@1,COG1139@2 NA|NA|NA C 4Fe-4S dicluster domain FFAGCILK_00746 543734.LCABL_22520 3.3e-149 534.3 Lactobacillaceae lutA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K18928 ko00000 iEC042_1314.EC042_0340,iEcSMS35_1347.EcSMS35_0338 Bacteria 1TPFC@1239,3F4GX@33958,4HAKC@91061,COG0247@1,COG0247@2 NA|NA|NA C Cysteine-rich domain FFAGCILK_00747 1423732.BALS01000017_gene1752 4.5e-84 317.4 Lactobacillaceae Bacteria 1U7F5@1239,2AYWY@1,30B2F@2,3F9II@33958,4IHB5@91061 NA|NA|NA FFAGCILK_00748 543734.LCABL_22540 1.8e-51 208.4 Bacilli chbA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0009987,GO:0015144,GO:0016043,GO:0016740,GO:0016772,GO:0016773,GO:0022607,GO:0022804,GO:0022857,GO:0034219,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0071702,GO:0071840,GO:0090563,GO:0090566,GO:1901264,GO:1902815 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 iECABU_c1320.ECABU_c17610,iECOK1_1307.ECOK1_1683,iECUMN_1333.ECUMN_2025,iNRG857_1313.NRG857_07575,iUMN146_1321.UM146_09345 Bacteria 1VEGE@1239,4HM37@91061,COG1447@1,COG1447@2 NA|NA|NA G Phosphotransferase system cellobiose-specific component IIA FFAGCILK_00749 543734.LCABL_22550 5.2e-209 733.4 Lactobacillaceae ko:K09963 ko00000 Bacteria 1TRIY@1239,3F4FK@33958,4H9V2@91061,COG3589@1,COG3589@2 NA|NA|NA S Bacterial protein of unknown function (DUF871) FFAGCILK_00750 543734.LCABL_22560 1.3e-69 268.9 Lactobacillaceae Bacteria 1VEZ0@1239,2DQNY@1,337UX@2,3F69F@33958,4HPE2@91061 NA|NA|NA S Domain of unknown function (DUF3284) FFAGCILK_00751 1423732.BALS01000017_gene1756 3.7e-07 60.5 Lactobacillaceae Bacteria 1U8DM@1239,29QP3@1,30BNR@2,3FAV9@33958,4IIBJ@91061 NA|NA|NA FFAGCILK_00752 543734.LCABL_22580 2.9e-265 920.6 Lactobacillaceae celB GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006793,GO:0006796,GO:0006810,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0044237,GO:0044238,GO:0044262,GO:0044464,GO:0046835,GO:0051179,GO:0051234,GO:0071702,GO:0071704,GO:0071944,GO:1901264,GO:1902815 2.7.1.207 ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 M00275,M00281 R04393,R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.1,4.A.3.2 iECABU_c1320.ECABU_c19930 Bacteria 1TP8D@1239,3F4VG@33958,4H9W2@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane FFAGCILK_00753 543734.LCABL_22590 0.0 1512.3 Lactobacillaceae rafA 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 Bacteria 1TQF4@1239,3F3RU@33958,4HA5R@91061,COG3345@1,COG3345@2 NA|NA|NA G alpha-galactosidase FFAGCILK_00754 543734.LCABL_22600 2.6e-135 488.0 Lactobacillaceae ko:K09861 ko00000 Bacteria 1TR33@1239,3F4KR@33958,4HFN2@91061,COG3022@1,COG3022@2 NA|NA|NA S Belongs to the UPF0246 family FFAGCILK_00755 543734.LCABL_22610 1e-136 492.7 Lactobacillaceae XK27_05520 Bacteria 1TPHH@1239,3F56B@33958,4HCHE@91061,COG3860@1,COG3860@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2087) FFAGCILK_00756 543734.LCABL_22620 0.0 1683.7 Lactobacillaceae VPA1266 3.1.11.5 ko:K01144,ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPZH@1239,3F5WR@33958,4HATQ@91061,COG0507@1,COG0507@2 NA|NA|NA L Helix-hairpin-helix containing domain FFAGCILK_00757 568703.LGG_02083 8.4e-81 306.6 Lactobacillaceae Bacteria 1U7BQ@1239,2AGPG@1,316X2@2,3F9AE@33958,4IH6V@91061 NA|NA|NA FFAGCILK_00758 568703.LGG_02085 3.7e-60 238.0 Lactobacillaceae Bacteria 1U7CC@1239,29Q1U@1,30B0E@2,3F9CG@33958,4IH7Q@91061 NA|NA|NA S WxL domain surface cell wall-binding FFAGCILK_00759 543734.LCABL_22650 1.7e-145 521.9 Lactobacillaceae frlD GO:0003674,GO:0003824,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0071704 2.7.1.218 ko:K10710 R08124 RC00002,RC00017 ko00000,ko01000 iECs_1301.ECs4224,iETEC_1333.ETEC_3624 Bacteria 1TSST@1239,3F7U3@33958,4HGU3@91061,COG0524@1,COG0524@2 NA|NA|NA G pfkB family carbohydrate kinase FFAGCILK_00760 543734.LCABL_22660 5.7e-104 383.6 Lactobacillaceae apc3 3.5.2.9 ko:K01469 ko00480,map00480 R00251 RC00553 ko00000,ko00001,ko01000 Bacteria 1TQVB@1239,3F4TR@33958,4HB8X@91061,COG0145@1,COG0145@2 NA|NA|NA EQ Hydantoinase/oxoprolinase N-terminal region FFAGCILK_00761 543734.LCABL_22690 6.6e-137 493.4 Lactobacillaceae Bacteria 1U7G9@1239,29Q4F@1,30B35@2,3F9KY@33958,4IHCF@91061 NA|NA|NA FFAGCILK_00762 543734.LCABL_22700 0.0 1349.3 Lactobacillaceae Bacteria 1TPAT@1239,3FB8C@33958,4HPJ0@91061,COG1479@1,COG1479@2 NA|NA|NA S Protein of unknown function (DUF1524) FFAGCILK_00763 1231377.C426_1885 4.8e-64 251.9 Lactococcus 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 1TP5N@1239,1YC2Y@1357,4I4F9@91061,COG0732@1,COG0732@2 NA|NA|NA V Type I restriction modification DNA specificity domain FFAGCILK_00764 543734.LCABL_22720 1.5e-172 612.1 Lactobacillaceae Bacteria 1TPE1@1239,3FC9T@33958,4HDHJ@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family FFAGCILK_00765 202752.JL53_02310 6.3e-67 261.5 Listeriaceae hsdS_1 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 1TP5N@1239,26KX7@186820,4HN7V@91061,COG0732@1,COG0732@2 NA|NA|NA V Type I restriction modification DNA specificity domain FFAGCILK_00766 1123312.KB904581_gene1112 4.4e-201 707.6 Bacilli hsdM 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 1TPGZ@1239,4HA1J@91061,COG0286@1,COG0286@2 NA|NA|NA V type I restriction-modification system FFAGCILK_00767 543734.LCABL_22760 0.0 1852.4 Lactobacillaceae hsdR 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 1TP7S@1239,3F50Q@33958,4HB5A@91061,COG0610@1,COG0610@2 NA|NA|NA V Subunit R is required for both nuclease and ATPase activities, but not for modification FFAGCILK_00768 543734.LCABL_22770 2.7e-76 291.6 Lactobacillaceae Bacteria 1V7X1@1239,2AYN8@1,31QSR@2,3F859@33958,4HIZR@91061 NA|NA|NA FFAGCILK_00769 543734.LCABL_22790 3.1e-212 744.2 Lactobacillaceae ykiI Bacteria 1VRUF@1239,2DSXT@1,32UTZ@2,3FB9G@33958,4HTM0@91061 NA|NA|NA FFAGCILK_00770 1423732.BALS01000016_gene1697 0.0 1157.1 Lactobacillaceae scrA 2.7.1.211 ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 Bacteria 1TP5X@1239,3F458@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system FFAGCILK_00771 543734.LCABL_22820 0.0 1162.1 Lactobacillaceae malA 3.2.1.10,3.2.1.20 ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13,GH31 Bacteria 1TP53@1239,3F41I@33958,4HA1G@91061,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain protein FFAGCILK_00772 543734.LCABL_22830 7.1e-181 639.8 Lactobacillaceae 5.1.1.1 ko:K01775,ko:K02529,ko:K05499 ko00473,ko01100,ko01502,map00473,map01100,map01502 R00401 RC00285 ko00000,ko00001,ko01000,ko01011,ko03000 Bacteria 1TRHK@1239,3F5FI@33958,4HB9P@91061,COG1609@1,COG1609@2 NA|NA|NA K Periplasmic binding proteins and sugar binding domain of LacI family FFAGCILK_00773 543734.LCABL_22840 1.5e-304 1051.2 Lactobacillaceae scrB 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 GH32 Bacteria 1TPAE@1239,3F4UD@33958,4H9Y7@91061,COG1621@1,COG1621@2 NA|NA|NA G invertase FFAGCILK_00774 543734.LCABL_22880 5.8e-163 580.1 Lactobacillaceae azoB Bacteria 1UY7W@1239,3F4M7@33958,4HDIS@91061,COG0702@1,COG0702@2 NA|NA|NA GM NmrA-like family FFAGCILK_00775 543734.LCABL_22890 1.7e-234 818.1 Lactobacillaceae cfa 2.1.1.317,2.1.1.79 ko:K00574,ko:K20238 ko00000,ko01000 Bacteria 1TSG4@1239,3F3PA@33958,4HDKI@91061,COG2230@1,COG2230@2 NA|NA|NA M cyclopropane-fatty-acyl-phospholipid synthase FFAGCILK_00776 543734.LCABL_22900 5e-142 510.4 Lactobacillaceae accA 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHNS@1239,3F496@33958,4HA4C@91061,COG0825@1,COG0825@2 NA|NA|NA I alpha subunit FFAGCILK_00777 543734.LCABL_22910 3.1e-150 537.7 Lactobacillaceae accD 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP4U@1239,3F3T6@33958,4HAI7@91061,COG0777@1,COG0777@2 NA|NA|NA I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA FFAGCILK_00778 1423732.BALS01000074_gene2115 9.4e-09 65.5 Lactobacillaceae Bacteria 1U8JX@1239,29QSF@1,30BSA@2,3FB2A@33958,4IIHW@91061 NA|NA|NA FFAGCILK_00779 543734.LCABL_22920 1.8e-256 891.3 Lactobacillaceae accC GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 iSF_1195.SF3294 Bacteria 1TP16@1239,3F3PT@33958,4HARK@91061,COG0439@1,COG0439@2 NA|NA|NA I Acetyl-CoA carboxylase biotin carboxylase subunit FFAGCILK_00780 543734.LCABL_22930 3.9e-75 287.3 Lactobacillaceae fabZ 3.5.1.108,4.2.1.59 ko:K02372,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212 M00060,M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 Bacteria 1V6EX@1239,3F5EE@33958,4HGX1@91061,COG0764@1,COG0764@2 NA|NA|NA I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs FFAGCILK_00781 543734.LCABL_22940 6.8e-59 233.4 Lactobacillaceae accB 2.3.1.12,4.1.1.3 ko:K00627,ko:K01571,ko:K02160 ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00307,M00376 R00209,R00217,R00742,R02569 RC00004,RC00040,RC00367,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000,ko02000 3.B.1.1.1 Bacteria 1VAB7@1239,3F7M1@33958,4HKCS@91061,COG0511@1,COG0511@2 NA|NA|NA I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA FFAGCILK_00782 543734.LCABL_22950 7e-223 779.6 Lactobacillaceae fabF 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPA7@1239,3F51H@33958,4H9SD@91061,COG0304@1,COG0304@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP FFAGCILK_00783 543734.LCABL_22960 4.7e-126 457.2 Lactobacillaceae Bacteria 1TP76@1239,3F4RI@33958,4HAA6@91061,COG1028@1,COG1028@2 NA|NA|NA IQ reductase FFAGCILK_00784 543734.LCABL_22970 2.1e-163 581.6 Lactobacillaceae fabD 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPB7@1239,3F3W9@33958,4HBCU@91061,COG0331@1,COG0331@2 NA|NA|NA I Malonyl CoA-acyl carrier protein transacylase FFAGCILK_00785 543734.LCABL_22980 1.8e-173 615.1 Lactobacillaceae fabK 1.3.1.9 ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 iHN637.CLJU_RS20775 Bacteria 1TPC3@1239,3F4PC@33958,4H9T0@91061,COG2070@1,COG2070@2 NA|NA|NA S Nitronate monooxygenase FFAGCILK_00786 543734.LCABL_22990 1.2e-33 148.7 Lactobacillaceae acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 ko:K02078 ko00000,ko00001 Bacteria 1VGIY@1239,3F7ZJ@33958,4HP0V@91061,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis FFAGCILK_00787 543734.LCABL_23000 5.9e-177 626.7 Lactobacillaceae fabH 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TP0K@1239,3F3XP@33958,4HATK@91061,COG0332@1,COG0332@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids FFAGCILK_00788 543734.LCABL_23010 6.2e-76 290.0 Lactobacillaceae marR Bacteria 1V6GY@1239,3FC7M@33958,4IR3W@91061,COG1846@1,COG1846@2 NA|NA|NA K Winged helix DNA-binding domain FFAGCILK_00789 543734.LCABL_23020 3.1e-72 277.7 Lactobacillaceae fabZ 3.5.1.108,4.2.1.59 ko:K02372,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212 M00060,M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 Bacteria 1V3UN@1239,3F77T@33958,4HHYD@91061,COG0764@1,COG0764@2 NA|NA|NA I FabA-like domain FFAGCILK_00791 543734.LCABL_23030 4.6e-193 680.2 Lactobacillaceae bioH 2.1.1.197,3.1.1.85,3.7.1.13,3.7.1.9,4.2.99.20 ko:K02169,ko:K02170,ko:K08680,ko:K10216,ko:K15756,ko:K16264 ko00130,ko00362,ko00621,ko00622,ko00643,ko00780,ko01100,ko01110,ko01120,ko01220,map00130,map00362,map00621,map00622,map00643,map00780,map01100,map01110,map01120,map01220 M00116,M00544,M00569,M00572 R02604,R05362,R05365,R05865,R08166,R09543,R09725 RC00003,RC00272,RC00460,RC00461,RC00753,RC00754,RC00755,RC00757,RC01337,RC01485,RC02148,RC02475 br01602,ko00000,ko00001,ko00002,ko01000,ko02000 2.A.4.1 Bacteria 1UM05@1239,3F97M@33958,4ITNF@91061,COG2021@1,COG2021@2 NA|NA|NA E Alpha/beta hydrolase family FFAGCILK_00792 543734.LCABL_23040 2.3e-226 791.2 Lactobacillaceae bdhA ko:K00100,ko:K19955 ko00650,ko01120,map00650,map01120 R03544,R03545 RC00087 ko00000,ko00001,ko01000 Bacteria 1TPS3@1239,3F4VF@33958,4H9TR@91061,COG1979@1,COG1979@2 NA|NA|NA C Iron-containing alcohol dehydrogenase FFAGCILK_00793 543734.LCABL_23070 1.4e-47 195.3 Lactobacillaceae Bacteria 1VGC1@1239,3F89N@33958,4HQJ6@91061,COG4367@1,COG4367@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2316) FFAGCILK_00794 543734.LCABL_23080 1.1e-66 259.2 Lactobacillaceae ko:K18909 M00705 ko00000,ko00002,ko01504,ko03000 Bacteria 1VMZX@1239,3FBM2@33958,4HMTC@91061,COG1846@1,COG1846@2 NA|NA|NA K MarR family FFAGCILK_00795 1423734.JCM14202_162 1.3e-12 80.5 Lactobacillaceae Bacteria 1UYJN@1239,3FBEE@33958,4HF8I@91061,COG4640@1,COG4640@2 NA|NA|NA S response to antibiotic FFAGCILK_00796 543734.LCABL_23100 2.1e-161 575.1 Lactobacillaceae Bacteria 1V856@1239,3F5Y5@33958,4HVCY@91061,COG0627@1,COG0627@2 NA|NA|NA S Putative esterase FFAGCILK_00797 543734.LCABL_23110 5.3e-198 696.8 Bacilli Bacteria 1W533@1239,28USJ@1,2ZGWS@2,4I1UJ@91061 NA|NA|NA FFAGCILK_00798 543734.LCABL_23120 2.4e-104 384.8 Lactobacillaceae rmaB Bacteria 1VF51@1239,3F725@33958,4HM7R@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator, MarR family FFAGCILK_00799 543734.LCABL_23130 0.0 1111.3 Lactobacillaceae lmrA 3.6.3.44 ko:K06147,ko:K18104 ko01501,ko02010,map01501,map02010 M00700 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 3.A.1.106,3.A.1.109,3.A.1.117,3.A.1.123,3.A.1.21 Bacteria 1TSY4@1239,3FC4S@33958,4HAJQ@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter FFAGCILK_00800 543734.LCABL_23140 3.8e-84 317.4 Lactobacillaceae Bacteria 1U7WX@1239,3F4BS@33958,4HHQT@91061,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain FFAGCILK_00801 543734.LCABL_23150 3.9e-130 470.7 Lactobacillaceae gpmA GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1TQFP@1239,3F3SK@33958,4HAW7@91061,COG0588@1,COG0588@2 NA|NA|NA G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate FFAGCILK_00802 568703.LGG_02139 3.4e-21 107.1 Lactobacillaceae Bacteria 1U7XJ@1239,2AWRG@1,31NNE@2,3FAAP@33958,4IHUY@91061 NA|NA|NA FFAGCILK_00803 543734.LCABL_23170 1.4e-121 443.0 Lactobacillaceae Bacteria 1VIMB@1239,3F7Z9@33958,4HP7R@91061,COG4640@1,COG4640@2 NA|NA|NA S zinc-ribbon domain FFAGCILK_00804 543734.LCABL_23180 6.5e-204 716.5 Lactobacillaceae pbpX1 Bacteria 1V4BS@1239,3F3QN@33958,4HJRT@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase FFAGCILK_00805 543734.LCABL_23190 7.1e-187 659.8 Lactobacillaceae Bacteria 1TSBK@1239,3F46E@33958,4HBYJ@91061,COG0628@1,COG0628@2 NA|NA|NA K AI-2E family transporter FFAGCILK_00806 543734.LCABL_23200 1.3e-128 465.7 Lactobacillaceae srtA 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria 1V4ZG@1239,3FBG7@33958,4HMUE@91061,COG3764@1,COG3764@2 NA|NA|NA M Sortase family FFAGCILK_00807 543734.LCABL_23210 6.5e-64 250.0 Lactobacillaceae gtcA GO:0000166,GO:0003674,GO:0003824,GO:0003870,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009987,GO:0016020,GO:0016410,GO:0016491,GO:0016620,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0016903,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 Bacteria 1VESW@1239,3F4GH@33958,4HNK7@91061,COG2246@1,COG2246@2 NA|NA|NA S Teichoic acid glycosylation protein FFAGCILK_00808 543734.LCABL_23220 3.6e-171 607.4 Lactobacillaceae ytlR 2.7.1.91 ko:K04718 ko00600,ko01100,ko04020,ko04071,ko04072,ko04370,ko04371,ko04666,ko05152,map00600,map01100,map04020,map04071,map04072,map04370,map04371,map04666,map05152 M00100 R01926,R02976 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQJH@1239,3F5ND@33958,4HJ8D@91061,COG1597@1,COG1597@2 NA|NA|NA I Diacylglycerol kinase catalytic domain FFAGCILK_00809 543734.LCABL_23230 0.0 1159.8 Lactobacillaceae poxB 1.2.3.3,1.2.5.1 ko:K00156,ko:K00158 ko00620,ko01100,map00620,map01100 R00207,R03145 RC00860,RC02745 ko00000,ko00001,ko01000 Bacteria 1TQE8@1239,3F3R9@33958,4HBUS@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family FFAGCILK_00810 543734.LCABL_23250 4e-167 594.0 Lactobacillaceae gbuC ko:K02001,ko:K02002 ko02010,map02010 M00208 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 1TP82@1239,3F4B3@33958,4H9MM@91061,COG2113@1,COG2113@2 NA|NA|NA E glycine betaine FFAGCILK_00811 543734.LCABL_23260 1.1e-147 529.3 Lactobacillaceae proW ko:K02001,ko:K02002 ko02010,map02010 M00208 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 1UHRI@1239,3F4W7@33958,4IS7D@91061,COG4176@1,COG4176@2 NA|NA|NA E glycine betaine FFAGCILK_00812 543734.LCABL_23270 4.5e-222 776.9 Lactobacillaceae gbuA 3.6.3.32 ko:K02000 ko02010,map02010 M00208 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.12 Bacteria 1UHNE@1239,3FC38@33958,4HA9P@91061,COG4175@1,COG4175@2 NA|NA|NA E glycine betaine FFAGCILK_00813 543734.LCABL_23280 7.8e-137 493.0 Lactobacillaceae sfsA ko:K06206 ko00000 Bacteria 1V1GZ@1239,3F4KV@33958,4HCPN@91061,COG1489@1,COG1489@2 NA|NA|NA S Belongs to the SfsA family FFAGCILK_00814 543734.LCABL_23290 1.8e-67 261.9 Lactobacillaceae usp1 Bacteria 1U62R@1239,3F6W5@33958,4IFRW@91061,COG0589@1,COG0589@2 NA|NA|NA T Universal stress protein family FFAGCILK_00815 543734.LCABL_23300 1.5e-252 878.2 Lactobacillaceae yxbA 6.3.1.12 ko:K17810 ko00000,ko01000 Bacteria 1TQPN@1239,3F3S7@33958,4HAB0@91061,COG3919@1,COG3919@2 NA|NA|NA S ATP-grasp enzyme FFAGCILK_00816 543734.LCABL_23310 1.1e-132 479.6 Lactobacillaceae thrB 2.7.1.39,4.2.3.1 ko:K00872,ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R01771,R05086 RC00002,RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 Bacteria 1TRWS@1239,3F44T@33958,4HCQN@91061,COG0083@1,COG0083@2 NA|NA|NA F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate FFAGCILK_00817 543734.LCABL_23320 2.1e-285 987.6 Lactobacillaceae thrC 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS16355,iIT341.HP0098 Bacteria 1TPR0@1239,3F3UF@33958,4H9R7@91061,COG0498@1,COG0498@2 NA|NA|NA E Threonine synthase FFAGCILK_00818 543734.LCABL_23330 2.4e-228 797.7 Lactobacillaceae hom 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS06610 Bacteria 1TQ2H@1239,3F5BM@33958,4HBAP@91061,COG0460@1,COG0460@2 NA|NA|NA E homoserine dehydrogenase FFAGCILK_00819 543734.LCABL_23340 3e-251 874.0 Lactobacillaceae yclM 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPQJ@1239,3F48V@33958,4HAEP@91061,COG0527@1,COG0527@2 NA|NA|NA E Belongs to the aspartokinase family FFAGCILK_00820 543734.LCABL_23350 5.7e-166 590.9 Lactobacillaceae yqiK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 ko:K03110,ko:K07192,ko:K07487,ko:K15125,ko:K18682 ko02024,ko03018,ko03060,ko03070,ko04910,ko05133,map02024,map03018,map03060,map03070,map04910,map05133 M00335 ko00000,ko00001,ko00002,ko00536,ko01000,ko02044,ko03019,ko03036,ko04131,ko04147 3.A.5.1,3.A.5.2,3.A.5.7 Bacteria 1TQDT@1239,3F5TM@33958,4HA0C@91061,COG2268@1,COG2268@2 NA|NA|NA S SPFH domain / Band 7 family FFAGCILK_00821 568703.LGG_02158 3.9e-39 167.5 Lactobacillaceae Bacteria 1VQB2@1239,2ESCD@1,33JX6@2,3F9Y6@33958,4HT0C@91061 NA|NA|NA FFAGCILK_00822 543734.LCABL_23370 2.5e-173 614.8 Lactobacillaceae pfoS ko:K07035 ko00000 Bacteria 1TS5F@1239,3FCB3@33958,4HC4N@91061,COG3641@1,COG3641@2 NA|NA|NA S Phosphotransferase system, EIIC FFAGCILK_00823 543734.LCABL_23380 8.3e-174 616.3 Lactobacillaceae ldhA 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 R00704 RC00044 ko00000,ko00001,ko01000 Bacteria 1TSZ6@1239,3F4US@33958,4HCIS@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family FFAGCILK_00824 543734.LCABL_23390 8.4e-218 762.7 Lactobacillaceae patA 2.6.1.1,2.6.1.57 ko:K00812,ko:K00832,ko:K00841,ko:K10907 ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00024,M00025,M00034,M00040,M00525 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R04467,R05052,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP0J@1239,3F3MX@33958,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase FFAGCILK_00825 543734.LCABL_23400 2.7e-49 201.1 Lactobacillaceae Bacteria 1U7X9@1239,2BNCG@1,32H06@2,3FAAB@33958,4IHUN@91061 NA|NA|NA FFAGCILK_00826 543734.LCABL_23410 1.6e-126 458.8 Lactobacillaceae WQ51_05710 Bacteria 1TPN2@1239,3F4J7@33958,4HHYG@91061,COG2013@1,COG2013@2 NA|NA|NA S Mitochondrial biogenesis AIM24 FFAGCILK_00827 543734.LCABL_23420 1.1e-70 272.3 Lactobacillaceae Bacteria 1VB6J@1239,3FCD8@33958,4HIE1@91061,COG0537@1,COG0537@2 NA|NA|NA FG Scavenger mRNA decapping enzyme C-term binding FFAGCILK_00828 543734.LCABL_23430 0.0 1291.6 Lactobacillaceae asnB 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 R00578 RC00010 ko00000,ko00001,ko01000,ko01002 Bacteria 1TRPB@1239,3F3NT@33958,4HAIP@91061,COG0367@1,COG0367@2 NA|NA|NA E Asparagine synthase FFAGCILK_00830 543734.LCABL_23460 1.7e-201 708.4 Lactobacillaceae Bacteria 1VMH1@1239,2EQYH@1,33II5@2,3F5E7@33958,4HUIK@91061 NA|NA|NA S Calcineurin-like phosphoesterase FFAGCILK_00831 543734.LCABL_23470 5.3e-159 567.0 Lactobacillaceae menA 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1TSZV@1239,3F3JM@33958,4HA68@91061,COG1575@1,COG1575@2 NA|NA|NA H 1,4-dihydroxy-2-naphthoate FFAGCILK_00832 543734.LCABL_23480 5.1e-176 623.6 Lactobacillaceae hepT 2.5.1.30,2.5.1.90 ko:K00805,ko:K02523 ko00900,ko01110,map00900,map01110 R09247,R09248 RC00279 ko00000,ko00001,ko01000,ko01006 Bacteria 1TR0U@1239,3F4GC@33958,4H9RH@91061,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family FFAGCILK_00833 543734.LCABL_23490 2.9e-221 774.2 Lactobacillaceae ackA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0409 Bacteria 1TQ22@1239,3F48Z@33958,4HA7K@91061,COG0282@1,COG0282@2 NA|NA|NA F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction FFAGCILK_00834 543734.LCABL_23500 7.4e-166 589.7 Bacilli natA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TR06@1239,4H9RX@91061,COG4152@1,COG4152@2 NA|NA|NA S abc transporter atp-binding protein FFAGCILK_00835 543734.LCABL_23510 1.3e-219 768.8 Lactobacillaceae ysdA ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TXRK@1239,3F3KA@33958,4HC9K@91061,COG1668@1,COG1668@2 NA|NA|NA CP ABC-2 family transporter protein FFAGCILK_00836 543734.LCABL_23520 9.6e-65 252.7 Lactobacillaceae ko:K07978,ko:K07979 ko00000,ko03000 Bacteria 1V9ZC@1239,3F78Z@33958,4HKSY@91061,COG1725@1,COG1725@2 NA|NA|NA K helix_turn_helix gluconate operon transcriptional repressor FFAGCILK_00837 543734.LCABL_23530 8.9e-164 582.8 Lactobacillaceae CcmA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPZR@1239,3F4BW@33958,4HB36@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter FFAGCILK_00838 543734.LCABL_23540 1.3e-111 409.1 Lactobacillaceae Bacteria 1UG9X@1239,3F8XZ@33958,4IGYH@91061,COG1835@1,COG1835@2 NA|NA|NA I ABC-2 family transporter protein FFAGCILK_00839 543734.LCABL_23550 2e-146 525.0 Lactobacillaceae Bacteria 1TRQC@1239,3F4FH@33958,4HD7P@91061,COG1028@1,COG1028@2 NA|NA|NA IQ reductase FFAGCILK_00840 543734.LCABL_23560 3.8e-199 700.7 Lactobacillaceae ald 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 R00396 RC00008 ko00000,ko00001,ko01000 Bacteria 1TNZ5@1239,3F4ZR@33958,4HABX@91061,COG0686@1,COG0686@2 NA|NA|NA C Belongs to the AlaDH PNT family FFAGCILK_00841 543734.LCABL_23570 1.4e-184 652.1 Lactobacillaceae tdcB GO:0003674,GO:0003824,GO:0003941,GO:0004793,GO:0004794,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006565,GO:0006566,GO:0006567,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016597,GO:0016829,GO:0016830,GO:0016832,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP22@1239,3F5KK@33958,4H9NK@91061,COG1171@1,COG1171@2 NA|NA|NA E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA FFAGCILK_00842 1423732.BALS01000018_gene1802 3e-297 1027.3 Lactobacillaceae Bacteria 1TQJP@1239,3F3KY@33958,4HB4S@91061,COG1297@1,COG1297@2 NA|NA|NA S OPT oligopeptide transporter protein FFAGCILK_00843 543734.LCABL_23600 4e-62 243.8 Lactobacillaceae Bacteria 1V931@1239,2E6A2@1,3182Z@2,3F77F@33958,4HNND@91061 NA|NA|NA S Coenzyme PQQ synthesis protein D (PqqD) FFAGCILK_00844 543734.LCABL_23610 1.2e-282 978.4 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase FFAGCILK_00845 543734.LCABL_23620 2.8e-257 894.0 Lactobacillaceae gor 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 Bacteria 1TS0Z@1239,3F3K2@33958,4HBYB@91061,COG1249@1,COG1249@2 NA|NA|NA C Glutathione reductase FFAGCILK_00846 543734.LCABL_23630 1.9e-248 864.8 Lactobacillaceae lmrB ko:K18926 M00715 ko00000,ko00002,ko02000 2.A.1.3.30 Bacteria 1TPRN@1239,3F4A2@33958,4H9VV@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily FFAGCILK_00847 543734.LCABL_23650 1e-96 359.4 Lactobacillaceae yxaF GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 ko:K16137,ko:K18939 M00715 ko00000,ko00002,ko03000 Bacteria 1UVV7@1239,3F8HZ@33958,4I435@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family FFAGCILK_00848 543734.LCABL_23660 2.8e-295 1020.4 Lactobacillaceae bglH 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3F3PQ@33958,4HA1W@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family FFAGCILK_00849 543734.LCABL_23670 0.0 1139.4 Lactobacillaceae bglP 2.7.1.199,2.7.1.208,2.7.1.211 ko:K02755,ko:K02756,ko:K02757,ko:K02790,ko:K02791,ko:K02809,ko:K02810 ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060 M00266,M00269,M00271 R00811,R02738,R04111 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.3,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9 Bacteria 1TP5X@1239,3F458@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system FFAGCILK_00850 543734.LCABL_23680 9.1e-153 546.2 Lactobacillaceae licT ko:K02531,ko:K02538,ko:K03488 ko00000,ko03000 Bacteria 1TT5A@1239,3F4SJ@33958,4HC5Y@91061,COG3711@1,COG3711@2 NA|NA|NA K CAT RNA binding domain FFAGCILK_00851 543734.LCABL_23690 8e-291 1005.7 Lactobacillaceae cydC ko:K06147,ko:K06148 ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1UHQP@1239,3F5XV@33958,4HC57@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region FFAGCILK_00852 543734.LCABL_23700 0.0 1093.2 Lactobacillaceae cydD ko:K06148 ko00000,ko02000 3.A.1 Bacteria 1TQ1P@1239,3F4VY@33958,4HCDA@91061,COG4988@1,COG4988@2 NA|NA|NA CO ABC transporter transmembrane region FFAGCILK_00853 543734.LCABL_23710 1.9e-74 285.0 Lactobacillaceae Bacteria 1VCR8@1239,3FBC0@33958,4HKP0@91061,COG5341@1,COG5341@2 NA|NA|NA S NusG domain II FFAGCILK_00854 568703.LGG_02198 3e-156 558.1 Lactobacillaceae Bacteria 1V2YC@1239,3F6TH@33958,4HFNB@91061,COG3409@1,COG3409@2 NA|NA|NA M Peptidoglycan-binding domain 1 protein FFAGCILK_00855 543734.LCABL_23750 3.2e-116 424.5 Lactobacillaceae Bacteria 1W4NV@1239,28XJS@1,2ZJGW@2,3F6XN@33958,4I15N@91061 NA|NA|NA S CRISPR-associated protein (Cas_Csn2) FFAGCILK_00856 543734.LCABL_23760 1.6e-46 191.8 Lactobacillaceae cas2 ko:K09951 ko00000,ko02048 Bacteria 1VEH4@1239,3F7KD@33958,4HNYR@91061,COG3512@1,COG3512@2 NA|NA|NA L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette FFAGCILK_00857 543734.LCABL_23770 2.1e-168 598.2 Lactobacillaceae cas1 ko:K15342 ko00000,ko02048,ko03400 Bacteria 1TT0J@1239,3F3RW@33958,4HC5E@91061,COG1518@1,COG1518@2 NA|NA|NA L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette FFAGCILK_00858 543734.LCABL_23780 0.0 2357.4 Lactobacillaceae cas9 ko:K09952 ko00000,ko01000,ko02048 Bacteria 1TPSD@1239,3F554@33958,4HE0R@91061,COG3513@1,COG3513@2 NA|NA|NA L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer FFAGCILK_00859 543734.LCABL_23790 6.3e-140 503.4 Lactobacillaceae Bacteria 1U6HW@1239,29PFB@1,30ADG@2,3F7Y8@33958,4IGA7@91061 NA|NA|NA FFAGCILK_00860 543734.LCABL_23800 1.5e-214 751.9 Lactobacillaceae ywhK Bacteria 1V841@1239,3F50M@33958,4HITC@91061,COG3391@1,COG3391@2 NA|NA|NA S Membrane FFAGCILK_00861 543734.LCABL_23810 3.8e-63 247.3 Lactobacillaceae Bacteria 1VF0I@1239,3F83V@33958,4HPC2@91061,COG5294@1,COG5294@2 NA|NA|NA S Protein of unknown function (DUF1093) FFAGCILK_00862 543734.LCABL_23820 4.2e-50 203.8 Lactobacillaceae yvlA Bacteria 1VIUB@1239,2DZIG@1,32VBI@2,3F7EN@33958,4HRZP@91061 NA|NA|NA FFAGCILK_00863 543734.LCABL_23830 0.0 1129.0 Lactobacillaceae cydD ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 3.A.1.129 Bacteria 1UHN5@1239,3F4PG@33958,4HAAB@91061,COG4987@1,COG4987@2 NA|NA|NA CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC FFAGCILK_00864 543734.LCABL_23840 0.0 1134.0 Lactobacillaceae cydD GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 3.A.1.129 Bacteria 1TQ1P@1239,3F451@33958,4HAN0@91061,COG4988@1,COG4988@2 NA|NA|NA CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD FFAGCILK_00865 543734.LCABL_23850 6.5e-182 643.3 Lactobacillaceae cydB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iECABU_c1320.ECABU_c10120,iLF82_1304.LF82_0101,iNRG857_1313.NRG857_04455,iPC815.YPO1118,iYO844.BSU38750,ic_1306.c1120 Bacteria 1TRYV@1239,3F40S@33958,4H9KF@91061,COG1294@1,COG1294@2 NA|NA|NA C Cytochrome d ubiquinol oxidase subunit II FFAGCILK_00866 543734.LCABL_23860 3e-278 963.8 Lactobacillaceae cydA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iPC815.YPO1117,iSBO_1134.SBO_2253,iSFxv_1172.SFxv_0621,iS_1188.S0577,iSbBS512_1146.SbBS512_E2337 Bacteria 1TRH4@1239,3F4MJ@33958,4HA19@91061,COG1271@1,COG1271@2 NA|NA|NA C ubiquinol oxidase FFAGCILK_00868 543734.LCABL_23870 6.5e-235 819.7 Lactobacillaceae pdp GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 ko:K00756,ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 R01570,R01876,R02296,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 iHN637.CLJU_RS08925 Bacteria 1TPCH@1239,3F45P@33958,4H9NP@91061,COG0213@1,COG0213@2 NA|NA|NA F pyrimidine-nucleoside phosphorylase FFAGCILK_00869 543734.LCABL_23880 7.2e-189 666.4 Lactobacillaceae add 3.5.4.4 ko:K01488,ko:K02029 ko00230,ko01100,ko05340,map00230,map01100,map05340 M00236 R01560,R02556 RC00477 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 iHN637.CLJU_RS13960 Bacteria 1U44B@1239,3F5RC@33958,4HCES@91061,COG1816@1,COG1816@2 NA|NA|NA F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism FFAGCILK_00870 543734.LCABL_23890 8.6e-40 169.1 Lactobacillaceae Bacteria 1U66C@1239,2900D@1,30NTF@2,3F8DT@33958,4IFWI@91061 NA|NA|NA FFAGCILK_00871 543734.LCABL_23900 5.5e-86 323.6 Lactobacillaceae Bacteria 1U5KG@1239,2CCK1@1,309S4@2,3F64Y@33958,4IFBA@91061 NA|NA|NA FFAGCILK_00872 543734.LCABL_23910 8e-24 115.5 Lactobacillaceae Bacteria 1U786@1239,29PYW@1,30AXC@2,3F93Q@33958,4IH32@91061 NA|NA|NA FFAGCILK_00873 543734.LCABL_23930 3.3e-138 497.7 Lactobacillaceae yicL Bacteria 1TR6G@1239,3F423@33958,4HAMD@91061,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family FFAGCILK_00874 543734.LCABL_23940 5.6e-112 410.2 Lactobacillaceae tag 3.2.2.20 ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1UYWG@1239,3F5KA@33958,4HGWW@91061,COG2818@1,COG2818@2 NA|NA|NA L glycosylase FFAGCILK_00875 543734.LCABL_23950 5e-78 297.0 Lactobacillaceae usp5 ko:K03499,ko:K06149 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1VEJR@1239,3F4Z0@33958,4HNHG@91061,COG0589@1,COG0589@2 NA|NA|NA T universal stress protein FFAGCILK_00876 568703.LGG_02218 1.8e-55 221.9 Lactobacillaceae Bacteria 1U7J6@1239,29Q5Z@1,30B4V@2,3F9SW@33958,4IHG0@91061 NA|NA|NA K Helix-turn-helix XRE-family like proteins FFAGCILK_00877 543734.LCABL_23970 4.2e-144 517.3 Lactobacillaceae ptp3 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1VBGE@1239,3FBJY@33958,4HN6J@91061,COG2365@1,COG2365@2 NA|NA|NA T Tyrosine phosphatase family FFAGCILK_00878 543734.LCABL_23980 6.5e-223 779.6 Lactobacillaceae queG GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 ko00000,ko01000,ko03016 Bacteria 1TP6Q@1239,3F5I3@33958,4HAEW@91061,COG1600@1,COG1600@2 NA|NA|NA C Domain of unknown function (DUF1730) FFAGCILK_00879 543734.LCABL_23990 1.7e-63 248.4 Lactobacillaceae Bacteria 1U6GD@1239,29PE3@1,30AC9@2,3F7V6@33958,4IG8H@91061 NA|NA|NA FFAGCILK_00880 543734.LCABL_24010 7.1e-87 326.6 Lactobacillaceae bioY GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 ko:K03523 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 Bacteria 1VAAD@1239,3F6YG@33958,4HI8T@91061,COG1268@1,COG1268@2 NA|NA|NA S BioY family FFAGCILK_00881 543734.LCABL_24020 3.5e-70 270.8 Lactobacillaceae adhR Bacteria 1VAAP@1239,3F6JI@33958,4HKZ9@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance FFAGCILK_00882 543734.LCABL_24030 7.9e-82 309.7 Lactobacillaceae Bacteria 1V465@1239,3F7H7@33958,4HN5X@91061,COG0716@1,COG0716@2 NA|NA|NA C Flavodoxin FFAGCILK_00883 543734.LCABL_24040 2.3e-198 698.0 Lactobacillaceae adh 1.1.1.1,1.1.1.14 ko:K00001,ko:K00008 ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 M00014 R00623,R00754,R00875,R01896,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00085,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPIW@1239,3F42F@33958,4HB2G@91061,COG1063@1,COG1063@2 NA|NA|NA E alcohol dehydrogenase FFAGCILK_00884 543734.LCABL_24050 2.2e-114 418.3 Lactobacillaceae Bacteria 1UJSC@1239,3F4ZZ@33958,4HCVT@91061,COG0702@1,COG0702@2 NA|NA|NA GM NmrA-like family FFAGCILK_00887 543734.LCABL_24080 4e-101 374.0 Bacteria Bacteria COG0500@1,COG2226@2 NA|NA|NA Q methyltransferase FFAGCILK_00888 543734.LCABL_24090 2.1e-95 355.9 Lactobacillaceae Bacteria 1VB6H@1239,3F66H@33958,4I1GZ@91061,COG3103@1,COG3103@2 NA|NA|NA T Sh3 type 3 domain protein FFAGCILK_00889 543734.LCABL_24100 4.5e-117 427.2 Lactobacillaceae yfeJ 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1UAH0@1239,3F4AV@33958,4HHTX@91061,COG0518@1,COG0518@2 NA|NA|NA F glutamine amidotransferase FFAGCILK_00890 543734.LCABL_24110 3e-99 367.9 Lactobacillaceae Bacteria 1VAHN@1239,3FBBD@33958,4HY6J@91061,COG4295@1,COG4295@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2263) FFAGCILK_00891 543734.LCABL_24120 5.3e-259 899.8 Lactobacillaceae yhdP ko:K03699,ko:K06189 ko00000,ko02000,ko02042 9.A.40.1.2 Bacteria 1TPN0@1239,3F3TX@33958,4H9SB@91061,COG1253@1,COG1253@2 NA|NA|NA S Transporter associated domain FFAGCILK_00892 543734.LCABL_24130 1.2e-258 898.7 Lactobacillaceae lmrB Bacteria 1TPRN@1239,3F4A2@33958,4H9VV@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily FFAGCILK_00893 568703.LGG_02232 2.8e-61 241.5 Lactobacillaceae Bacteria 1U5T4@1239,2C9UQ@1,309VR@2,3F6FU@33958,4IFH1@91061 NA|NA|NA S Domain of unknown function (DUF4811) FFAGCILK_00894 543734.LCABL_24150 9.9e-100 369.4 Lactobacillaceae maf GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0030428,GO:0032506,GO:0044085,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0090529,GO:1902410,GO:1903047 ko:K06287 ko00000 Bacteria 1V6FH@1239,3F65C@33958,4HIMK@91061,COG0424@1,COG0424@2 NA|NA|NA D nucleoside-triphosphate diphosphatase activity FFAGCILK_00895 543734.LCABL_24160 0.0 1269.2 Lactobacillaceae mutL GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1TPGK@1239,3F3PK@33958,4HB34@91061,COG0323@1,COG0323@2 NA|NA|NA L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex FFAGCILK_00896 543734.LCABL_24170 0.0 1646.3 Lactobacillaceae mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1TPRJ@1239,3F4A5@33958,4HA63@91061,COG0249@1,COG0249@2 NA|NA|NA L that it carries out the mismatch recognition step. This protein has a weak ATPase activity FFAGCILK_00897 543734.LCABL_24180 0.0 1138.6 Lactobacillaceae ydaO GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 Bacteria 1TQE1@1239,3F44Y@33958,4HAZH@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid FFAGCILK_00898 543734.LCABL_24190 2.4e-56 224.6 Lactobacillaceae Bacteria 1W3MW@1239,2EUB0@1,33MTD@2,3F7TK@33958,4HZUX@91061 NA|NA|NA S Domain of unknown function (DUF1827) FFAGCILK_00899 543734.LCABL_24200 1e-293 1015.4 Lactobacillaceae groL GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 1TP1T@1239,3F3MM@33958,4HA38@91061,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions FFAGCILK_00900 1423732.BALS01000008_gene814 6.7e-44 183.0 Lactobacillaceae groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0032991,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:0101031,GO:1903506,GO:1990220,GO:2000112,GO:2001141 ko:K04078 ko00000,ko03029,ko03110 Bacteria 1V9ZM@1239,3F7CZ@33958,4HKEK@91061,COG0234@1,COG0234@2 NA|NA|NA O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter FFAGCILK_00901 543734.LCABL_24220 8.5e-111 406.4 Lactobacillaceae ko:K07052 ko00000 Bacteria 1UZGJ@1239,3F5JU@33958,4HFCB@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity FFAGCILK_00902 543734.LCABL_24230 8.2e-196 689.5 Lactobacillaceae brpA Bacteria 1TR1B@1239,3F3MQ@33958,4HA09@91061,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-like function transcriptional attenuator common domain protein FFAGCILK_00903 543734.LCABL_24240 1e-174 619.4 Lactobacillaceae Bacteria 1U6YM@1239,2DKT0@1,30APV@2,3F8QM@33958,4IGSU@91061 NA|NA|NA FFAGCILK_00904 543734.LCABL_24250 1.1e-158 565.8 Lactobacillaceae ytrB ko:K01990,ko:K16921 ko02010,map02010 M00254,M00584 ko00000,ko00001,ko00002,ko02000 3.A.1 Bacteria 1TPQW@1239,3FC3A@33958,4HA3P@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter FFAGCILK_00905 543734.LCABL_24260 2.7e-61 241.1 Lactobacillaceae ytrA ko:K07978,ko:K07979 ko00000,ko03000 Bacteria 1VFD0@1239,3F7AX@33958,4HNIT@91061,COG1725@1,COG1725@2 NA|NA|NA K helix_turn_helix gluconate operon transcriptional repressor FFAGCILK_00906 543734.LCABL_24270 7.2e-118 429.9 Lactobacillaceae rex ko:K01926 ko00000,ko03000 Bacteria 1TSMR@1239,3F40G@33958,4HB7Q@91061,COG2344@1,COG2344@2 NA|NA|NA K Modulates transcription in response to changes in cellular NADH NAD( ) redox state FFAGCILK_00907 543734.LCABL_24280 0.0 1220.3 Lactobacillaceae uup ko:K06158 ko00000,ko03012 Bacteria 1TPAX@1239,3F3QI@33958,4HBVV@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter, ATP-binding protein FFAGCILK_00908 543734.LCABL_24290 3.9e-51 207.2 Lactobacillaceae 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 Bacteria 1VADE@1239,3F6GU@33958,4HKG9@91061,COG1440@1,COG1440@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit FFAGCILK_00909 543734.LCABL_24300 4.2e-189 667.2 Lactobacillaceae tsaD GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 R10648 RC00070,RC00416 ko00000,ko00001,ko00002,ko01000,ko02044,ko03016 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 1TQDR@1239,3F4AX@33958,4HANB@91061,COG0533@1,COG0533@2 NA|NA|NA J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction FFAGCILK_00910 543734.LCABL_24310 2.1e-99 368.2 Lactobacillaceae rimI 2.3.1.128 ko:K03789 ko00000,ko01000,ko03009 Bacteria 1V6KU@1239,3F522@33958,4HIKU@91061,COG0454@1,COG0456@2 NA|NA|NA K Ribosomal-protein-alanine acetyltransferase FFAGCILK_00911 543734.LCABL_24320 5.3e-130 470.3 Lactobacillaceae yeaZ GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K14742 R10648 RC00070,RC00416 ko00000,ko01000,ko03016 Bacteria 1V4YX@1239,3F3WV@33958,4HHD7@91061,COG1214@1,COG1214@2 NA|NA|NA O Universal bacterial protein YeaZ FFAGCILK_00912 1423732.BALS01000008_gene801 4.6e-74 284.3 Lactobacillaceae Bacteria 1U7CF@1239,2AQ5J@1,31FAY@2,3F9CK@33958,4IH7T@91061 NA|NA|NA FFAGCILK_00913 543734.LCABL_24340 9.6e-89 332.8 Lactobacillaceae folT 2.7.13.3 ko:K02478,ko:K07704 ko02020,map02020 M00492 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1VB87@1239,3FBSH@33958,4ISET@91061,COG3275@1,COG3275@2 NA|NA|NA T ECF transporter, substrate-specific component FFAGCILK_00914 543734.LCABL_24350 1.1e-178 632.5 Lactobacillaceae ansA 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 R00485 RC00010,RC02798 ko00000,ko00001,ko01000 Bacteria 1TPP9@1239,3F3XA@33958,4H9YJ@91061,COG0252@1,COG0252@2 NA|NA|NA EJ Asparaginase FFAGCILK_00915 1235801.C822_00413 1.9e-34 152.5 Lactobacillaceae Bacteria 1TVFA@1239,29XQD@1,30JG1@2,3FAZJ@33958,4I1PS@91061 NA|NA|NA S Phospholipase A2 FFAGCILK_00917 543734.LCABL_24360 5.7e-143 513.5 Lactobacillaceae fat 3.1.2.21 ko:K01071 ko00061,ko01100,map00061,map01100 R04014,R08157,R08158 RC00014,RC00039 ko00000,ko00001,ko01000,ko01004 Bacteria 1V3RB@1239,3F41B@33958,4HHJ4@91061,COG3884@1,COG3884@2 NA|NA|NA I Acyl-ACP thioesterase FFAGCILK_00918 543734.LCABL_24370 4.5e-144 517.3 Lactobacillaceae rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 ko:K07056 ko00000,ko01000,ko03009 Bacteria 1TP6U@1239,3F4AI@33958,4HAH8@91061,COG0313@1,COG0313@2 NA|NA|NA H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA FFAGCILK_00919 543734.LCABL_24380 2.2e-57 228.0 Lactobacillaceae yabA GO:0003674,GO:0005488,GO:0005515,GO:0042802 Bacteria 1VA1F@1239,3F864@33958,4HKND@91061,COG4467@1,COG4467@2 NA|NA|NA L Involved in initiation control of chromosome replication FFAGCILK_00920 543734.LCABL_24390 1.2e-172 612.5 Lactobacillaceae holB 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TRVS@1239,3F50D@33958,4HA3T@91061,COG0470@1,COG0470@2 NA|NA|NA L DNA polymerase III FFAGCILK_00921 543734.LCABL_24400 4.6e-52 210.3 Lactobacillaceae yaaQ Bacteria 1V6NI@1239,3F6VW@33958,4HIHA@91061,COG3870@1,COG3870@2 NA|NA|NA S Cyclic-di-AMP receptor FFAGCILK_00922 543734.LCABL_24410 5.1e-116 423.7 Lactobacillaceae tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS02535 Bacteria 1V1HE@1239,3F4JR@33958,4HGWR@91061,COG0125@1,COG0125@2 NA|NA|NA F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis FFAGCILK_00924 568703.LGG_02263 5.8e-34 149.8 Lactobacillaceae Bacteria 1U6HS@1239,2DKQT@1,30ADD@2,3F7Y1@33958,4IGA3@91061 NA|NA|NA S Protein of unknown function (DUF2508) FFAGCILK_00925 543734.LCABL_24430 1.3e-108 399.1 Lactobacillaceae recR GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1TR87@1239,3F4JQ@33958,4HAZR@91061,COG0353@1,COG0353@2 NA|NA|NA L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO FFAGCILK_00926 543734.LCABL_24440 8.4e-32 142.9 Lactobacillaceae yaaK ko:K09747 ko00000 Bacteria 1VA1S@1239,3F7F3@33958,4HKH3@91061,COG0718@1,COG0718@2 NA|NA|NA S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection FFAGCILK_00927 543734.LCABL_24450 0.0 1092.8 Lactobacillaceae dnaX GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 ko:K02341,ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TPS9@1239,3F3P2@33958,4HAUE@91061,COG2812@1,COG2812@2 NA|NA|NA L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity FFAGCILK_00928 543734.LCABL_24460 3.8e-90 337.4 Lactobacillaceae tadA GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 ko:K11991 R10223 RC00477 ko00000,ko01000,ko03016 Bacteria 1V3HZ@1239,3F6IS@33958,4HH7S@91061,COG0590@1,COG0590@2 NA|NA|NA F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) FFAGCILK_00929 543734.LCABL_24470 5.6e-50 203.4 Lactobacillaceae Bacteria 1VKX3@1239,2EMDH@1,33F2E@2,3F709@33958,4HR5Y@91061 NA|NA|NA FFAGCILK_00930 543734.LCABL_24480 9e-107 392.9 Lactobacillaceae rsmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.172 ko:K00564 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 1V1BG@1239,3F4NU@33958,4HHCA@91061,COG2813@1,COG2813@2 NA|NA|NA J Methyltransferase FFAGCILK_00931 543734.LCABL_24490 0.0 1688.7 Lactobacillaceae mprF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 ko:K07027,ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00726 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 2.A.1.3.37,4.D.2 iYO844.BG12900 Bacteria 1TQI2@1239,3F3PY@33958,4HBHU@91061,COG0392@1,COG0392@2,COG2898@1,COG2898@2 NA|NA|NA S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms FFAGCILK_00932 1423816.BACQ01000053_gene2052 1.8e-45 188.7 Lactobacillaceae Bacteria 1U7NB@1239,2BJY6@1,32EAT@2,3F9XZ@33958,4IHJK@91061 NA|NA|NA FFAGCILK_00933 543734.LCABL_24510 8.3e-176 622.9 Lactobacillaceae ccpB 5.1.1.1 ko:K01775,ko:K02529,ko:K05499 ko00473,ko01100,ko01502,map00473,map01100,map01502 R00401 RC00285 ko00000,ko00001,ko01000,ko01011,ko03000 Bacteria 1TQSQ@1239,3F4YI@33958,4HBNR@91061,COG1609@1,COG1609@2 NA|NA|NA K lacI family FFAGCILK_00934 543734.LCABL_24520 0.0 3205.6 Lactobacillaceae prtS 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652,ko:K17734 ko00000,ko01000,ko01002,ko03110 Bacteria 1TPH1@1239,3F3M5@33958,4HBQH@91061,COG1404@1,COG1404@2 NA|NA|NA O Belongs to the peptidase S8 family FFAGCILK_00935 543734.LCABL_24530 1.9e-156 558.5 Lactobacillaceae prsA 5.2.1.8 ko:K02597,ko:K07533 ko00000,ko01000,ko03110 Bacteria 1VT0K@1239,3F4RW@33958,4I4BP@91061,COG0760@1,COG0760@2 NA|NA|NA M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins FFAGCILK_00936 543734.LCABL_24540 1.1e-49 202.6 Lactobacillaceae rplL ko:K02935 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6EI@1239,3F6YA@33958,4HIGQ@91061,COG0222@1,COG0222@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation FFAGCILK_00937 543734.LCABL_24550 6.5e-82 310.1 Lactobacillaceae rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02864,ko:K02935 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3JJ@1239,3F4S4@33958,4HH0N@91061,COG0244@1,COG0244@2 NA|NA|NA J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors FFAGCILK_00938 543734.LCABL_24560 3e-221 774.2 Lactobacillaceae mdtG GO:0006810,GO:0006855,GO:0008150,GO:0015893,GO:0042221,GO:0042493,GO:0050896,GO:0051179,GO:0051234,GO:0055085 ko:K08161 ko00000,ko02000 2.A.1.2.20 Bacteria 1TRDJ@1239,3F3T5@33958,4H9Q9@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily FFAGCILK_00939 543734.LCABL_24570 1.5e-155 555.4 Lactobacillaceae Bacteria 1V42X@1239,3F6TI@33958,4HI1M@91061,COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase FFAGCILK_00940 1423816.BACQ01000053_gene2060 1.8e-66 258.8 Lactobacillaceae Bacteria 1U7BG@1239,29Q17@1,30AZR@2,3F99Z@33958,4IH6H@91061 NA|NA|NA FFAGCILK_00941 543734.LCABL_24590 1.5e-217 761.9 Lactobacillaceae yceI ko:K08369 ko00000,ko02000 2.A.1 Bacteria 1UHSG@1239,3FBXF@33958,4IS86@91061,COG2271@1,COG2271@2 NA|NA|NA G Sugar (and other) transporter FFAGCILK_00942 543734.LCABL_24600 1.5e-261 908.3 Lactobacillaceae gabD 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP4S@1239,3F47F@33958,4H9MF@91061,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family FFAGCILK_00943 543734.LCABL_24610 1.3e-122 445.7 Lactobacillaceae rplA GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02863 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPTS@1239,3F3VQ@33958,4HAK4@91061,COG0081@1,COG0081@2 NA|NA|NA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release FFAGCILK_00944 543734.LCABL_24620 8.2e-70 269.6 Lactobacillaceae rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02867 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1BS@1239,3F64I@33958,4HFQ0@91061,COG0080@1,COG0080@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors FFAGCILK_00945 543734.LCABL_24630 0.0 1665.6 Lactobacillaceae mgtA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0099131,GO:0099132 3.6.3.2,3.6.3.6 ko:K01531,ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 3.A.3.3,3.A.3.4 iSF_1195.SF4248 Bacteria 1TPF5@1239,3F4E0@33958,4HBQJ@91061,COG0474@1,COG0474@2 NA|NA|NA P COG0474 Cation transport ATPase FFAGCILK_00946 543734.LCABL_24640 2.2e-268 931.0 Lactobacillaceae nylA 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 Bacteria 1TPGJ@1239,3F4UM@33958,4HBE7@91061,COG0154@1,COG0154@2 NA|NA|NA J Belongs to the amidase family FFAGCILK_00947 543734.LCABL_24650 2.1e-66 258.1 Lactobacillaceae frataxin ko:K05937 ko00000 Bacteria 1V6QT@1239,3F79K@33958,4HIUI@91061,COG5646@1,COG5646@2 NA|NA|NA S Domain of unknown function (DU1801) FFAGCILK_00948 543734.LCABL_24660 1.1e-92 345.9 Lactobacillaceae yvqK GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.2.1.88,1.5.5.2,2.5.1.17 ko:K00798,ko:K13821 ko00250,ko00330,ko00860,ko01100,ko01110,ko01130,map00250,map00330,map00860,map01100,map01110,map01130 M00122 R00245,R00707,R00708,R01253,R01492,R04444,R04445,R05051,R05220,R07268 RC00080,RC00083,RC00216,RC00242,RC00255,RC00533 ko00000,ko00001,ko00002,ko01000,ko03000 Bacteria 1V3PI@1239,3FBQY@33958,4IS1C@91061,COG2096@1,COG2096@2 NA|NA|NA S Cobalamin adenosyltransferase FFAGCILK_00949 543734.LCABL_24670 5.8e-95 353.6 Lactobacillaceae ko:K16924,ko:K16927 M00582 ko00000,ko00002,ko02000 3.A.1.29,3.A.1.32 Bacteria 1V5GD@1239,3F5H7@33958,4HI8Y@91061,COG4720@1,COG4720@2 NA|NA|NA S ECF transporter, substrate-specific component FFAGCILK_00950 543734.LCABL_24680 5.1e-63 246.9 Lactobacillaceae Bacteria 1VF26@1239,2DNM7@1,32Y2X@2,3F6AM@33958,4HP82@91061 NA|NA|NA S Domain of unknown function (DUF4430) FFAGCILK_00951 543734.LCABL_24690 0.0 1538.5 Lactobacillaceae rtpR 1.1.98.6,1.17.4.1,1.17.4.2 ko:K00525,ko:K00527,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02014,R02017,R02018,R02019,R02020,R02022,R02023,R02024,R04315,R11633,R11634,R11635,R11636 RC00013,RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1TT3U@1239,3F3VU@33958,4HFF1@91061,COG0209@1,COG0209@2 NA|NA|NA F ribonucleoside-triphosphate reductase activity FFAGCILK_00952 543734.LCABL_24700 5e-78 297.0 Lactobacillaceae Bacteria 1U5KZ@1239,3F74G@33958,4IFBV@91061,COG3613@1,COG3613@2 NA|NA|NA F Nucleoside 2-deoxyribosyltransferase FFAGCILK_00953 543734.LCABL_24710 1.7e-159 568.5 Lactobacillaceae Bacteria 1V910@1239,3F4RX@33958,4HF90@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha/beta hydrolase of unknown function (DUF915) FFAGCILK_00954 543734.LCABL_24720 3.4e-100 370.9 Lactobacillaceae nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K02601 ko00000,ko03009,ko03021 Bacteria 1TR3P@1239,3F55W@33958,4HAJA@91061,COG0250@1,COG0250@2 NA|NA|NA K Participates in transcription elongation, termination and antitermination FFAGCILK_00955 543734.LCABL_24730 5.7e-22 109.4 Lactobacillaceae secE GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1VK48@1239,3F86Y@33958,4HR1W@91061,COG0690@1,COG0690@2 NA|NA|NA U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation FFAGCILK_00956 543734.LCABL_24740 5.7e-172 610.1 Lactobacillaceae menA 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1TSZV@1239,3F3JM@33958,4HA68@91061,COG1575@1,COG1575@2 NA|NA|NA H 1,4-dihydroxy-2-naphthoate FFAGCILK_00957 543734.LCABL_24750 9e-170 602.8 Lactobacillaceae menA 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1TSZV@1239,3F6SN@33958,4HA68@91061,COG1575@1,COG1575@2 NA|NA|NA M UbiA prenyltransferase family FFAGCILK_00958 543734.LCABL_24760 4e-198 697.2 Lactobacillaceae apbE 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria 1TR9C@1239,3FB4B@33958,4HA6Y@91061,COG1477@1,COG1477@2 NA|NA|NA H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein FFAGCILK_00959 543734.LCABL_24770 2.6e-137 495.0 Lactobacillaceae cad ko:K20379 ko02024,map02024 ko00000,ko00001 Bacteria 1V2YY@1239,3FBKH@33958,4HGMF@91061,COG4939@1,COG4939@2 NA|NA|NA S FMN_bind FFAGCILK_00960 543734.LCABL_24780 0.0 1233.8 Lactobacillaceae ndh 1.6.99.3 ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 1TR6X@1239,3F4N1@33958,4HA14@91061,COG1252@1,COG1252@2 NA|NA|NA C NADH dehydrogenase FFAGCILK_00961 543734.LCABL_24790 3.1e-80 304.3 Lactobacillaceae ynhH Bacteria 1VCR8@1239,3F7R1@33958,4HMR5@91061,COG5341@1,COG5341@2 NA|NA|NA S NusG domain II FFAGCILK_00962 543734.LCABL_24800 1.2e-98 365.9 Lactobacillaceae gerCA 2.5.1.30 ko:K00805 ko00900,ko01110,map00900,map01110 R09247 RC00279 ko00000,ko00001,ko01000,ko01006 Bacteria 1V1M0@1239,3F3R8@33958,4HG1H@91061,COG4769@1,COG4769@2 NA|NA|NA S Heptaprenyl diphosphate synthase component I FFAGCILK_00963 543734.LCABL_24810 1.9e-178 631.7 Lactobacillaceae hepT 2.5.1.30,2.5.1.90 ko:K00805,ko:K02523 ko00900,ko01110,map00900,map01110 R09247,R09248 RC00279 ko00000,ko00001,ko01000,ko01006 Bacteria 1TR0U@1239,3F4GC@33958,4H9RH@91061,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family FFAGCILK_00965 543734.LCABL_24830 1.3e-122 445.7 Lactobacillaceae 1.5.1.40 ko:K06988 ko00000,ko01000 Bacteria 1UXZM@1239,3FB9A@33958,4HDRH@91061,COG2085@1,COG2085@2 NA|NA|NA S Rossmann-like domain FFAGCILK_00966 543734.LCABL_24840 3.3e-189 667.5 Lactobacillaceae XK27_00915 Bacteria 1TRBN@1239,3F4KZ@33958,4HBYT@91061,COG2141@1,COG2141@2 NA|NA|NA C Luciferase-like monooxygenase FFAGCILK_00967 568703.LGG_02318 7.2e-121 440.3 Lactobacillaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQA2@1239,3FC3N@33958,4HEU0@91061,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities FFAGCILK_00968 568703.LGG_02319 2.7e-174 618.2 Lactobacillaceae Bacteria 1TT1Z@1239,28MM7@1,2ZAX4@2,3F45B@33958,4HDYX@91061 NA|NA|NA FFAGCILK_00969 568703.LGG_02320 6.3e-146 523.9 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1UZZX@1239,28MJI@1,2ZAW0@2,3F5KU@33958,4HCUA@91061 NA|NA|NA FFAGCILK_00971 568703.LGG_02316 1.7e-101 375.9 Lactobacillaceae Bacteria 1U79G@1239,2AGH5@1,316PQ@2,3F95I@33958,4IH4B@91061 NA|NA|NA FFAGCILK_00972 543734.LCABL_24850 2.4e-98 364.8 Lactobacillaceae yacP ko:K06962 ko00000 Bacteria 1V9XR@1239,3F5KC@33958,4HFW4@91061,COG3688@1,COG3688@2 NA|NA|NA S YacP-like NYN domain FFAGCILK_00973 543734.LCABL_24860 3.3e-141 507.7 Lactobacillaceae trmH GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218,ko:K03437,ko:K12952 ko00000,ko01000,ko03009,ko03016 3.A.3.23 Bacteria 1TP9G@1239,3F3TD@33958,4HBBI@91061,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family FFAGCILK_00974 543734.LCABL_24870 8.5e-75 286.2 Lactobacillaceae mrnC GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 ko:K11145 ko00000,ko01000,ko03009 Bacteria 1VA5V@1239,3F6HS@33958,4HIM3@91061,COG1939@1,COG1939@2 NA|NA|NA J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) FFAGCILK_00975 543734.LCABL_24880 1e-273 948.7 Lactobacillaceae cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16,6.3.1.13 ko:K01883,ko:K15526 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iECUMN_1333.ECUMN_0566,iJN746.PP_2905 Bacteria 1TP9D@1239,3F4K7@33958,4HA6D@91061,COG0215@1,COG0215@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family FFAGCILK_00976 543734.LCABL_24890 8.7e-262 909.1 Lactobacillaceae loxD 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 R00475 RC00042 ko00000,ko00001,ko01000 Bacteria 1TPBC@1239,3F4AD@33958,4H9UU@91061,COG0277@1,COG0277@2 NA|NA|NA C FAD linked oxidases, C-terminal domain FFAGCILK_00977 543734.LCABL_24900 2.7e-108 397.9 Lactobacillaceae Bacteria 1U7NE@1239,29Q7Y@1,30B6Z@2,3F9Y4@33958,4IHJP@91061 NA|NA|NA FFAGCILK_00979 543734.LCABL_24920 6.2e-274 949.5 Lactobacillaceae gltX GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009986,GO:0030246,GO:0030247,GO:0044424,GO:0044464,GO:2001065 6.1.1.17,6.1.1.24 ko:K01885,ko:K09698 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 iSB619.SA_RS02860 Bacteria 1TPJC@1239,3F3PR@33958,4HAKH@91061,COG0008@1,COG0008@2 NA|NA|NA J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) FFAGCILK_00980 543734.LCABL_24930 1.1e-186 659.1 Lactobacillaceae XK27_10475 Bacteria 1TPT5@1239,3F4XH@33958,4HAPJ@91061,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold FFAGCILK_00981 543734.LCABL_24940 2.2e-117 428.3 Lactobacillaceae rpiA GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 iJN678.rpiA Bacteria 1W0HS@1239,3F757@33958,4HZEY@91061,COG0120@1,COG0120@2 NA|NA|NA G Ribose 5-phosphate isomerase A (phosphoriboisomerase A) FFAGCILK_00982 543734.LCABL_24950 9.1e-142 509.6 Lactobacillaceae Bacteria 1UYAM@1239,3FC4F@33958,4HVUK@91061,COG1737@1,COG1737@2 NA|NA|NA K SIS domain FFAGCILK_00983 543734.LCABL_24960 8.2e-114 416.8 Lactobacillaceae yhfC Bacteria 1V3UF@1239,3F7XI@33958,4HEYB@91061,COG4377@1,COG4377@2 NA|NA|NA S Putative membrane peptidase family (DUF2324) FFAGCILK_00984 543734.LCABL_24980 1.8e-176 625.2 Lactobacillaceae Bacteria 1UY2R@1239,3F7N8@33958,4HEEQ@91061,COG4194@1,COG4194@2 NA|NA|NA S Membrane FFAGCILK_00985 543734.LCABL_24990 2.7e-61 241.1 Lactobacillaceae ko:K07979 ko00000,ko03000 Bacteria 1V743@1239,3F8MP@33958,4HJDB@91061,COG1725@1,COG1725@2 NA|NA|NA K helix_turn_helix gluconate operon transcriptional repressor FFAGCILK_00986 543734.LCABL_25040 9.2e-218 762.7 Lactobacillaceae inlJ Bacteria 1UWF2@1239,3F6D1@33958,4HGU0@91061,COG4932@1,COG4932@2 NA|NA|NA M MucBP domain FFAGCILK_00987 1423816.BACQ01000056_gene2171 4.7e-190 671.4 Lactobacillaceae comA GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.112.1,3.A.1.21 Bacteria 1V77J@1239,3F3QF@33958,4HAX2@91061,COG2274@1,COG2274@2 NA|NA|NA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain FFAGCILK_00988 543734.LCABL_25050 4.3e-77 294.7 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V1GX@1239,3F52P@33958,4HG2P@91061,COG1277@1,COG1277@2 NA|NA|NA S ABC-2 family transporter protein FFAGCILK_00989 543734.LCABL_25060 1.4e-106 392.9 Lactobacillaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TP4J@1239,3F3YW@33958,4HBGH@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter, ATP-binding protein FFAGCILK_00990 543734.LCABL_25070 6.4e-117 427.2 Lactobacillaceae ko:K20374,ko:K21405 ko02024,map02024 ko00000,ko00001,ko03000 Bacteria 1U7HF@1239,3F9PR@33958,4IHE2@91061,COG1396@1,COG1396@2 NA|NA|NA K sequence-specific DNA binding FFAGCILK_00991 543734.LCABL_25080 3.3e-203 714.1 Lactobacillaceae yacL GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 Bacteria 1TP0P@1239,3F46T@33958,4H9NQ@91061,COG4956@1,COG4956@2 NA|NA|NA S domain protein FFAGCILK_00992 543734.LCABL_25090 6.5e-254 882.9 Lactobacillaceae radA ko:K04485 ko00000,ko03400 Bacteria 1TQ7Y@1239,3F3W8@33958,4H9YC@91061,COG1066@1,COG1066@2 NA|NA|NA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function FFAGCILK_00993 543734.LCABL_25100 4.3e-100 370.5 Lactobacillaceae dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23,4.1.1.36,6.3.2.5 ko:K01520,ko:K13038 ko00240,ko00770,ko00983,ko01100,map00240,map00770,map00983,map01100 M00053,M00120 R02100,R03269,R04231,R11896 RC00002,RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1V6HX@1239,3FB45@33958,4HIZ3@91061,COG0756@1,COG0756@2 NA|NA|NA F dUTPase FFAGCILK_00994 543734.LCABL_25110 9.9e-51 205.7 Lactobacillaceae HA62_12640 ko:K06975 ko00000 Bacteria 1VEEX@1239,3F80F@33958,4HNR2@91061,COG2388@1,COG2388@2 NA|NA|NA S GCN5-related N-acetyl-transferase FFAGCILK_00995 543734.LCABL_25120 9.5e-70 269.2 Lactobacillaceae Bacteria 1VZ1N@1239,3FCFB@33958,4HY6Y@91061,COG3152@1,COG3152@2 NA|NA|NA S Protein of unknown function (DUF805) FFAGCILK_00996 543734.LCABL_25130 3.6e-257 893.6 Lactobacillaceae pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 ko00000,ko01000,ko01002 Bacteria 1TRJN@1239,3F3QA@33958,4HBZ9@91061,COG3579@1,COG3579@2 NA|NA|NA E aminopeptidase FFAGCILK_00997 543734.LCABL_25140 9.3e-261 905.6 Lactobacillaceae pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 ko00000,ko01000,ko01002 Bacteria 1TRJN@1239,3F49B@33958,4HBZ9@91061,COG3579@1,COG3579@2 NA|NA|NA E Peptidase C1-like family FFAGCILK_00998 543734.LCABL_25150 9.1e-198 696.0 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1UZZX@1239,28MJI@1,2ZAW0@2,3F5KU@33958,4HCUA@91061 NA|NA|NA FFAGCILK_00999 543734.LCABL_25160 4.3e-217 760.4 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1UJ2G@1239,28MM7@1,2Z8B9@2,3FBU3@33958,4ISZP@91061 NA|NA|NA S ABC-2 family transporter protein FFAGCILK_01000 543734.LCABL_25170 1.1e-166 592.4 Lactobacillaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQA2@1239,3FC3N@33958,4HEU0@91061,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities FFAGCILK_01001 543734.LCABL_25180 0.0 1337.4 Lactobacillaceae kup GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 ko:K03549 ko00000,ko02000 2.A.72 Bacteria 1TRUQ@1239,3F4CU@33958,4HA8Z@91061,COG3158@1,COG3158@2 NA|NA|NA P Transport of potassium into the cell FFAGCILK_01002 543734.LCABL_25190 0.0 1702.2 Lactobacillaceae ppdK 2.7.9.1 ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPK8@1239,3FBUR@33958,4HBU2@91061,COG0574@1,COG0574@2,COG1080@1,COG1080@2 NA|NA|NA G Belongs to the PEP-utilizing enzyme family FFAGCILK_01003 543734.LCABL_25200 3.1e-93 347.8 Lactobacillaceae ccpN GO:0006355,GO:0007154,GO:0007584,GO:0008150,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0042221,GO:0045013,GO:0045892,GO:0045934,GO:0045990,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 Bacteria 1TRZD@1239,3F6K8@33958,4HC4C@91061,COG0517@1,COG0517@2 NA|NA|NA K Domain in cystathionine beta-synthase and other proteins. FFAGCILK_01004 543734.LCABL_25210 7.7e-123 446.4 Lactobacillaceae gpmA GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1V2UT@1239,3F443@33958,4HGRK@91061,COG0588@1,COG0588@2 NA|NA|NA G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate FFAGCILK_01005 543734.LCABL_25220 5.4e-206 723.4 Lactobacillaceae ltrA Bacteria 1VAA8@1239,3FBQ1@33958,4IRU7@91061,COG4292@1,COG4292@2 NA|NA|NA S Bacterial low temperature requirement A protein (LtrA) FFAGCILK_01006 543734.LCABL_25230 7.2e-46 189.5 Lactobacillaceae Bacteria 1W32Y@1239,294CX@1,2ZRSX@2,3F85H@33958,4I1C7@91061 NA|NA|NA FFAGCILK_01007 543734.LCABL_25240 1.9e-206 724.9 Lactobacillaceae lctO ko:K10530 ko00000,ko01000 Bacteria 1TPC4@1239,3F3N3@33958,4HAU5@91061,COG1304@1,COG1304@2 NA|NA|NA C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases FFAGCILK_01008 543734.LCABL_25250 1e-09 68.9 Bacteria yhjA Bacteria COG3237@1,COG3237@2 NA|NA|NA K CsbD-like FFAGCILK_01009 575605.ACQN01000041_gene998 7e-08 63.2 Lactobacillaceae Bacteria 1U6CF@1239,2DKPT@1,30A91@2,3F7KP@33958,4IG44@91061 NA|NA|NA FFAGCILK_01010 543734.LCABL_25320 1.9e-32 144.4 Lactobacillaceae Bacteria 1U6Z6@1239,29PRZ@1,30AQ7@2,3F8RC@33958,4IGTF@91061 NA|NA|NA FFAGCILK_01011 543734.LCABL_25330 1.3e-38 165.2 Lactobacillaceae Bacteria 1U6Y5@1239,2DKSV@1,30APG@2,3F8PU@33958,4IGSB@91061 NA|NA|NA FFAGCILK_01012 543734.LCABL_25340 3.7e-224 783.9 Lactobacillaceae pimH Bacteria 1TRUT@1239,3F5PJ@33958,4HFIF@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily FFAGCILK_01013 1423732.BALS01000031_gene61 2.4e-202 711.4 Lactobacillaceae proA GO:0003674,GO:0003824,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 iB21_1397.B21_00243,iECBD_1354.ECBD_3376,iECB_1328.ECB_00240,iECD_1391.ECD_00240,iLJ478.TM0293,iYL1228.KPN_00280,iYO844.BSU13130 Bacteria 1TQ9V@1239,3F3W7@33958,4HB7B@91061,COG0014@1,COG0014@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate FFAGCILK_01014 543734.LCABL_25360 6.1e-146 523.5 Lactobacillaceae proB GO:0003674,GO:0003824,GO:0004349,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016772,GO:0016774,GO:0016903,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPG6@1239,3F4E1@33958,4HA9B@91061,COG0263@1,COG0263@2 NA|NA|NA F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate FFAGCILK_01016 1423732.BALS01000031_gene63 3.1e-42 178.3 Lactobacillaceae Bacteria 1U7IZ@1239,29Q5T@1,30B4Q@2,3F9SF@33958,4IHFS@91061 NA|NA|NA FFAGCILK_01017 543734.LCABL_25380 4.5e-230 803.5 Lactobacillaceae ywhK Bacteria 1V841@1239,3F50M@33958,4HITC@91061,COG3391@1,COG3391@2 NA|NA|NA S Membrane FFAGCILK_01018 543734.LCABL_25390 3.2e-147 527.7 Lactobacillaceae 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria 1UN9R@1239,3FCAD@33958,4HG4C@91061,COG3764@1,COG3764@2 NA|NA|NA M Sortase family FFAGCILK_01019 543734.LCABL_25400 1.4e-297 1028.1 Lactobacillaceae Bacteria 1UY9B@1239,3F6KV@33958,4HW31@91061,COG4932@1,COG4932@2 NA|NA|NA M Cna protein B-type domain FFAGCILK_01020 543734.LCABL_25410 4.4e-239 833.6 Bacilli Bacteria 1UM06@1239,2EZ87@1,33SE3@2,4ITNG@91061 NA|NA|NA FFAGCILK_01021 543734.LCABL_25420 0.0 1955.6 Lactobacillaceae Bacteria 1VRZM@1239,3F8GT@33958,4HTFC@91061,COG4932@1,COG4932@2 NA|NA|NA M domain protein FFAGCILK_01022 1423816.BACQ01000072_gene2585 6.2e-102 376.7 Lactobacillaceae Bacteria 1UPXG@1239,2AYWY@1,31R2N@2,3F66A@33958,4IVCM@91061 NA|NA|NA FFAGCILK_01023 543734.LCABL_25440 1.5e-230 805.1 Lactobacillaceae ko:K09384 ko00000 Bacteria 1TPQU@1239,3F47M@33958,4HBI0@91061,COG3410@1,COG3410@2 NA|NA|NA N Uncharacterized conserved protein (DUF2075) FFAGCILK_01024 543734.LCABL_25450 3e-206 724.2 Lactobacillaceae MA20_36090 Bacteria 1UF81@1239,3FBVJ@33958,4HI1Q@91061,COG1073@1,COG1073@2 NA|NA|NA S Protein of unknown function (DUF2974) FFAGCILK_01025 543734.LCABL_25460 1.2e-77 296.2 Lactobacillaceae Bacteria 1VEKB@1239,3F84P@33958,4HH0D@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins FFAGCILK_01026 543734.LCABL_25470 7.5e-55 219.5 Lactobacillaceae ko:K10947 ko00000,ko03000 Bacteria 1VAGB@1239,3F7N2@33958,4HKBS@91061,COG1695@1,COG1695@2 NA|NA|NA K Transcriptional regulator PadR-like family FFAGCILK_01027 568703.LGG_02378 1.7e-65 256.1 Lactobacillaceae Bacteria 1U7AB@1239,2AG9B@1,30AYZ@2,3F976@33958,4IH59@91061 NA|NA|NA FFAGCILK_01028 543734.LCABL_25490 3.8e-137 494.2 Lactobacillaceae Bacteria 1U7AB@1239,2AG9B@1,30AYZ@2,3F976@33958,4IH59@91061 NA|NA|NA FFAGCILK_01029 543734.LCABL_25500 5.4e-46 189.9 Lactobacillaceae Bacteria 1W247@1239,2DEZ9@1,2ZPV3@2,3F8UH@33958,4I0IP@91061 NA|NA|NA S Enterocin A Immunity FFAGCILK_01030 543734.LCABL_25510 3.6e-45 187.2 Bacilli Bacteria 1W247@1239,2DEZ9@1,2ZPV3@2,4I0IP@91061 NA|NA|NA S Enterocin A Immunity FFAGCILK_01031 543734.LCABL_25520 3.1e-44 184.1 Lactobacillaceae spiA ko:K18831 ko00000,ko02048,ko03000 Bacteria 1UM07@1239,3F86R@33958,4ITNH@91061,COG1476@1,COG1476@2 NA|NA|NA K TRANSCRIPTIONal FFAGCILK_01032 543734.LCABL_25530 1.5e-250 871.7 Lactobacillaceae yjjP Bacteria 1TNZH@1239,3F4FR@33958,4HU4D@91061,COG2966@1,COG2966@2,COG3610@1,COG3610@2 NA|NA|NA S Putative threonine/serine exporter FFAGCILK_01034 543734.LCABL_25560 2.7e-54 217.6 Lactobacillaceae Bacteria 1U8E8@1239,2BTF9@1,32NMI@2,3FAW0@33958,4IIC5@91061 NA|NA|NA FFAGCILK_01035 543734.LCABL_25570 1.3e-222 778.9 Lactobacillaceae mesE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 3.A.1.112,8.A.1,8.A.1.4.2 Bacteria 1V5C8@1239,3F5W4@33958,4HHKB@91061,COG0845@1,COG0845@2 NA|NA|NA M Transport protein ComB FFAGCILK_01036 1423816.BACQ01000056_gene2171 0.0 1288.1 Lactobacillaceae comA GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.112.1,3.A.1.21 Bacteria 1V77J@1239,3F3QF@33958,4HAX2@91061,COG2274@1,COG2274@2 NA|NA|NA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain FFAGCILK_01038 543734.LCABL_25610 8.4e-134 483.8 Bacteria 2.7.13.3 ko:K02476,ko:K07706 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria COG3290@1,COG3290@2 NA|NA|NA T protein histidine kinase activity FFAGCILK_01039 543734.LCABL_25620 9.5e-144 516.2 Lactobacillaceae plnD ko:K07707 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko02022 Bacteria 1V392@1239,3F3VI@33958,4HHAI@91061,COG3279@1,COG3279@2 NA|NA|NA K LytTr DNA-binding domain FFAGCILK_01041 1423816.BACQ01000056_gene2181 8.6e-10 68.9 Lactobacillaceae Bacteria 1U866@1239,2AIQB@1,31972@2,3FAKI@33958,4II3R@91061 NA|NA|NA FFAGCILK_01045 543734.LCABL_25670 8e-141 506.5 Lactobacillaceae ko:K07052 ko00000 Bacteria 1W74D@1239,3F80E@33958,4HXYG@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity FFAGCILK_01046 543734.LCABL_25690 2.6e-55 221.1 Lactobacillaceae Bacteria 1U77W@1239,29PYM@1,30AX3@2,3F935@33958,4IH2P@91061 NA|NA|NA FFAGCILK_01048 543734.LCABL_25720 3.8e-54 217.2 Lactobacillaceae Bacteria 1W39Y@1239,2CCCW@1,2ZFAQ@2,3F8D6@33958,4I054@91061 NA|NA|NA S Enterocin A Immunity FFAGCILK_01049 543734.LCABL_25730 3.2e-104 384.4 Lactobacillaceae yncA 2.3.1.79 ko:K00661 ko00000,ko01000 Bacteria 1TQEX@1239,3F59K@33958,4HAJ0@91061,COG0110@1,COG0110@2 NA|NA|NA S Maltose acetyltransferase FFAGCILK_01053 543734.LCABL_25770 3e-181 641.0 Lactobacillaceae Bacteria 1TQ12@1239,3F4U1@33958,4HA57@91061,COG4989@1,COG4989@2 NA|NA|NA S Aldo keto reductase FFAGCILK_01054 543734.LCABL_25780 2.7e-121 441.4 Lactobacillaceae Bacteria 1TRHF@1239,3F468@33958,4HBXH@91061,COG4221@1,COG4221@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family FFAGCILK_01055 543734.LCABL_25790 1.3e-213 748.8 Lactobacillaceae yqiG Bacteria 1TPM6@1239,3F3UQ@33958,4HAS5@91061,COG1902@1,COG1902@2 NA|NA|NA C Oxidoreductase FFAGCILK_01056 543734.LCABL_25800 1.9e-253 881.3 Lactobacillaceae fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHPH@1239,3F3K0@33958,4HA6P@91061,COG0114@1,COG0114@2 NA|NA|NA C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate FFAGCILK_01057 543734.LCABL_25810 1.3e-134 485.7 Lactobacillaceae Bacteria 1U7C1@1239,29Q1N@1,30B08@2,3F9BP@33958,4IH7B@91061 NA|NA|NA FFAGCILK_01058 543734.LCABL_25820 2.1e-15 87.0 Lactobacillaceae Bacteria 1U8AV@1239,2BSE3@1,32MG2@2,3FASA@33958,4II8V@91061 NA|NA|NA FFAGCILK_01059 543734.LCABL_25830 1.4e-260 905.2 Lactobacillaceae mntH GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 ko:K03322 ko00000,ko02000 2.A.55.2.6,2.A.55.3 Bacteria 1TPT1@1239,3F49Y@33958,4HAEA@91061,COG1914@1,COG1914@2 NA|NA|NA P H( )-stimulated, divalent metal cation uptake system FFAGCILK_01060 543734.LCABL_25840 0.0 1663.3 Lactobacillaceae pacL Bacteria 1TPF5@1239,3F3KP@33958,4H9S5@91061,COG0474@1,COG0474@2 NA|NA|NA P P-type ATPase FFAGCILK_01061 1423732.BALS01000064_gene2233 4.9e-55 220.3 Lactobacillaceae Bacteria 1U7IM@1239,29PE3@1,32D7A@2,3F9RV@33958,4IHFA@91061 NA|NA|NA FFAGCILK_01062 543734.LCABL_25860 3.2e-240 837.4 Lactobacillaceae Bacteria 1UJ8F@1239,3FBUG@33958,4IT4C@91061,COG0477@1,COG0477@2 NA|NA|NA EGP Major Facilitator Superfamily FFAGCILK_01063 543734.LCABL_25870 0.0 1086.6 Lactobacillaceae mco Bacteria 1TQSU@1239,3F3XB@33958,4HDD6@91061,COG2132@1,COG2132@2 NA|NA|NA Q Multicopper oxidase FFAGCILK_01064 543734.LCABL_25880 1.2e-25 121.7 Lactobacillaceae Bacteria 1VZEN@1239,2FB4N@1,343B1@2,3F944@33958,4HYPA@91061 NA|NA|NA FFAGCILK_01065 543734.LCABL_25890 6.4e-111 406.8 Lactobacillaceae 2.5.1.105 ko:K04088,ko:K06897 ko00790,map00790 M00742 R10339 RC00121 ko00000,ko00001,ko00002,ko01000 Bacteria 1V9B6@1239,3F4M1@33958,4HJTJ@91061,COG0053@1,COG0053@2 NA|NA|NA P Cation efflux family FFAGCILK_01066 543734.LCABL_25900 5.4e-53 213.4 Lactobacillaceae czrA ko:K21903,ko:K22043 ko00000,ko03000 Bacteria 1VA6G@1239,3F7DH@33958,4HKYT@91061,COG0640@1,COG0640@2 NA|NA|NA K Transcriptional regulator, ArsR family FFAGCILK_01067 543734.LCABL_25920 7.6e-177 626.3 Lactobacillaceae sitA GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0042597,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 ko:K09818,ko:K11601,ko:K11604,ko:K19975,ko:K19976 ko02010,ko02020,map02010,map02020 M00243,M00316,M00317,M00792 ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.1,3.A.1.15.15,3.A.1.15.7,3.A.1.15.9 iECED1_1282.ECED1_1296 Bacteria 1TRKU@1239,3F4B9@33958,4HAKT@91061,COG0803@1,COG0803@2 NA|NA|NA P Belongs to the bacterial solute-binding protein 9 family FFAGCILK_01068 543734.LCABL_25930 3.6e-144 517.7 Lactobacillaceae mtsB GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 ko:K09819,ko:K19975,ko:K19976 ko02010,map02010 M00243,M00792 ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.15 Bacteria 1TPZB@1239,3F4JM@33958,4HBD7@91061,COG1108@1,COG1108@2 NA|NA|NA U ABC 3 transport family FFAGCILK_01069 543734.LCABL_25940 3.4e-132 477.6 Firmicutes mntB 3.6.3.35 ko:K02074,ko:K11710,ko:K19973 ko02010,map02010 M00244,M00319,M00792 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.15 Bacteria 1UM08@1239,COG1121@1,COG1121@2 NA|NA|NA P AAA domain, putative AbiEii toxin, Type IV TA system FFAGCILK_01070 543734.LCABL_25950 1.1e-275 955.3 Lactobacillaceae aldA GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004029,GO:0004777,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006004,GO:0006082,GO:0006105,GO:0006520,GO:0006536,GO:0006538,GO:0006540,GO:0006807,GO:0008150,GO:0008152,GO:0008911,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009448,GO:0009450,GO:0009987,GO:0016043,GO:0016052,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0019299,GO:0019301,GO:0019317,GO:0019318,GO:0019320,GO:0019752,GO:0022607,GO:0032787,GO:0036094,GO:0042133,GO:0042135,GO:0042354,GO:0042355,GO:0042802,GO:0043436,GO:0043648,GO:0043649,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046395,GO:0048037,GO:0050569,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051287,GO:0051289,GO:0055114,GO:0065003,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.21,1.2.1.22 ko:K07248 ko00620,ko00630,ko01120,map00620,map00630,map01120 R00203,R01333,R01446 RC00080,RC00104,RC00242 ko00000,ko00001,ko01000 iAF1260.b1415,iBWG_1329.BWG_1242,iECDH10B_1368.ECDH10B_1541,iECDH1ME8569_1439.ECDH1ME8569_1358,iEcDH1_1363.EcDH1_2230,iJO1366.b1415,iJR904.b1415,iY75_1357.Y75_RS07435 Bacteria 1TP4S@1239,3F47F@33958,4H9MF@91061,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family FFAGCILK_01071 543734.LCABL_25960 5e-41 173.3 Lactobacillaceae rpsN GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02954 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEF6@1239,3F7KX@33958,4HKK1@91061,COG0199@1,COG0199@2 NA|NA|NA J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site FFAGCILK_01072 543734.LCABL_25990 1.5e-166 592.0 Lactobacillaceae znuA ko:K02077 M00244 ko00000,ko00002,ko02000 3.A.1.15 Bacteria 1V110@1239,3FBJR@33958,4HZ7G@91061,COG0803@1,COG0803@2 NA|NA|NA P Belongs to the bacterial solute-binding protein 9 family FFAGCILK_01073 543734.LCABL_26000 1.2e-117 429.1 Lactobacillaceae Bacteria 1UJSC@1239,3F4ZZ@33958,4HCVT@91061,COG0702@1,COG0702@2 NA|NA|NA GM NmrA-like family FFAGCILK_01074 543734.LCABL_26010 4.4e-112 410.6 Lactobacillaceae yjhB 3.6.1.13,3.6.1.55 ko:K01515,ko:K03574 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000,ko03400 Bacteria 1U7WX@1239,3F4BS@33958,4HHQT@91061,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain FFAGCILK_01075 543734.LCABL_26020 2.6e-70 271.6 Lactobacillaceae Bacteria 1U7MC@1239,29Q79@1,30B6A@2,3F9WH@33958,4IHIH@91061 NA|NA|NA FFAGCILK_01076 543734.LCABL_26030 3.3e-52 211.1 Lactobacillaceae Bacteria 1TQBI@1239,3F4FM@33958,4HBAT@91061,COG4932@1,COG4932@2 NA|NA|NA M domain protein FFAGCILK_01078 543734.LCABL_26040 1.3e-165 589.0 Lactobacillaceae znuA ko:K02077 M00244 ko00000,ko00002,ko02000 3.A.1.15 Bacteria 1V110@1239,3FBJR@33958,4HZ7G@91061,COG0803@1,COG0803@2 NA|NA|NA P Belongs to the bacterial solute-binding protein 9 family FFAGCILK_01079 543734.LCABL_26060 6.1e-20 102.4 Lactobacillaceae Bacteria 1U8AT@1239,29QM9@1,30BKW@2,3FAS5@33958,4II8S@91061 NA|NA|NA FFAGCILK_01080 525309.HMPREF0494_2131 2.3e-38 166.4 Lactobacillaceae Bacteria 1U5R7@1239,2CC5Z@1,309UP@2,3F6CR@33958,4IFF8@91061 NA|NA|NA S zinc-ribbon domain FFAGCILK_01082 1423816.BACQ01000060_gene2301 6.8e-95 355.5 Bacteria Bacteria 2ED61@1,3372S@2 NA|NA|NA FFAGCILK_01085 543734.LCABL_14610 1.3e-17 96.3 Bacilli Bacteria 1TPFS@1239,4HD09@91061,COG3039@1,COG3039@2 NA|NA|NA L Transposase FFAGCILK_01086 543734.LCABL_26100 1.9e-51 208.4 Lactobacillaceae crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria 1VM30@1239,3F8A8@33958,4HRC4@91061,COG0239@1,COG0239@2 NA|NA|NA U Important for reducing fluoride concentration in the cell, thus reducing its toxicity FFAGCILK_01087 543734.LCABL_26110 4.3e-68 263.8 Lactobacillaceae crcB ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria 1U4G6@1239,3F6R4@33958,4IE88@91061,COG0239@1,COG0239@2 NA|NA|NA U Important for reducing fluoride concentration in the cell, thus reducing its toxicity FFAGCILK_01090 1423734.JCM14202_2530 2.4e-221 774.6 Lactobacillaceae eno GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0043236,GO:0050840 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Bacteria 1V12I@1239,3FCCA@33958,4HTD2@91061,COG0148@1,COG0148@2 NA|NA|NA G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis FFAGCILK_01091 1114972.AUAW01000012_gene1149 7.5e-231 807.0 Lactobacillaceae 3.6.3.6 ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 3.A.3.3 Bacteria 1TPF5@1239,3F55J@33958,4HVA4@91061,COG0474@1,COG0474@2 NA|NA|NA P Cation transporter/ATPase, N-terminus FFAGCILK_01092 543734.LCABL_26140 2.3e-157 561.6 Lactobacillaceae phnD ko:K02044 ko02010,map02010 M00223 ko00000,ko00001,ko00002,ko02000 3.A.1.9 Bacteria 1TR0H@1239,3F3KK@33958,4HBJQ@91061,COG3221@1,COG3221@2 NA|NA|NA P Phosphonate ABC transporter FFAGCILK_01093 543734.LCABL_26150 2.8e-137 494.6 Lactobacillaceae phnC GO:0006810,GO:0008150,GO:0015716,GO:0051179,GO:0051234,GO:0071702 3.6.3.28 ko:K02041 ko02010,map02010 M00223 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 Bacteria 1TQG6@1239,3F3SJ@33958,4HC3N@91061,COG3638@1,COG3638@2 NA|NA|NA P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system FFAGCILK_01094 543734.LCABL_26160 7.8e-135 486.5 Lactobacillaceae phnE 3.6.1.63 ko:K02042,ko:K06162 ko00440,ko02010,map00440,map02010 M00223 R10186 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 Bacteria 1TR1S@1239,3F58M@33958,4HBT8@91061,COG3639@1,COG3639@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component FFAGCILK_01095 543734.LCABL_26170 5e-145 520.4 Lactobacillaceae phnE 3.6.1.63 ko:K02042,ko:K06162 ko00440,ko02010,map00440,map02010 M00223 R10186 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 Bacteria 1TQ73@1239,3FBJQ@33958,4HBI5@91061,COG3639@1,COG3639@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component FFAGCILK_01096 543734.LCABL_26190 6.2e-174 616.7 Lactobacillaceae ssuA ko:K15553 ko00920,ko02010,map00920,map02010 M00436 ko00000,ko00001,ko00002,ko02000 3.A.1.17.2 Bacteria 1TPI2@1239,3F4DK@33958,4HDP6@91061,COG0715@1,COG0715@2 NA|NA|NA P NMT1-like family FFAGCILK_01097 543734.LCABL_26200 1.2e-291 1008.4 Lactobacillaceae 6.2.1.3,6.2.1.8 ko:K01897,ko:K22133 ko00061,ko00071,ko00630,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00630,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280,R01558 RC00004,RC00014,RC00179 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 1TPSX@1239,3FC48@33958,4HA2G@91061,COG0318@1,COG0318@2 NA|NA|NA IQ AMP-binding enzyme C-terminal domain FFAGCILK_01098 543734.LCABL_26210 3.4e-233 813.9 Lactobacillaceae yfiQ Bacteria 1V8A9@1239,3F5JA@33958,4HJ67@91061,COG1835@1,COG1835@2 NA|NA|NA I Acyltransferase family FFAGCILK_01099 543734.LCABL_26220 1.2e-115 422.5 Lactobacillaceae ssuB GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K02049,ko:K15555 ko00920,ko02010,map00920,map02010 M00188,M00436 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.2 Bacteria 1TRE2@1239,3F5YE@33958,4HAHM@91061,COG1116@1,COG1116@2 NA|NA|NA P ATPases associated with a variety of cellular activities FFAGCILK_01100 543734.LCABL_26230 2.7e-146 524.6 Lactobacillaceae ssuC ko:K15554 ko00920,ko02010,map00920,map02010 M00436 ko00000,ko00001,ko00002,ko02000 3.A.1.17.2 Bacteria 1TQ26@1239,3F4W8@33958,4HCJ7@91061,COG0600@1,COG0600@2 NA|NA|NA U Binding-protein-dependent transport system inner membrane component FFAGCILK_01101 543734.LCABL_26240 5.6e-133 480.3 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TR4N@1239,3F5Q6@33958,4HDII@91061,COG3694@1,COG3694@2 NA|NA|NA S ABC-2 family transporter protein FFAGCILK_01102 543734.LCABL_26250 1.7e-134 485.3 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TSAN@1239,3F66B@33958,4HFPQ@91061,COG4587@1,COG4587@2 NA|NA|NA S ABC-2 family transporter protein FFAGCILK_01103 543734.LCABL_26260 8.9e-133 479.9 Lactobacillaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TP1N@1239,3F5QG@33958,4H9NR@91061,COG4586@1,COG4586@2 NA|NA|NA S ABC transporter FFAGCILK_01104 568703.LGG_00380 1.7e-32 145.6 Lactobacillaceae Bacteria 1V564@1239,299D6@1,2ZWG2@2,3F6SE@33958,4HI66@91061 NA|NA|NA S Protein of unknown function (DUF2785) FFAGCILK_01105 543734.LCABL_26300 1e-83 317.0 Lactobacillaceae Bacteria 1U82X@1239,2BQ3C@1,32IXT@2,3FAGQ@33958,4II0B@91061 NA|NA|NA FFAGCILK_01106 543734.LCABL_26310 7.4e-55 219.5 Lactobacillaceae Bacteria 1TVPM@1239,2E9Y3@1,32JRV@2,3FA3I@33958,4I3SR@91061 NA|NA|NA FFAGCILK_01107 1423732.BALS01000005_gene1111 1.1e-65 255.8 Lactobacillaceae rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02996 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3MQ@1239,3F656@33958,4HH3B@91061,COG0103@1,COG0103@2 NA|NA|NA J Belongs to the universal ribosomal protein uS9 family FFAGCILK_01108 543734.LCABL_26330 2.4e-80 304.7 Lactobacillaceae rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02871 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3HX@1239,3F696@33958,4HG0I@91061,COG0102@1,COG0102@2 NA|NA|NA J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly FFAGCILK_01109 543734.LCABL_26340 1.2e-106 392.5 Lactobacillaceae ko:K09017 ko00000,ko03000 Bacteria 1VD4H@1239,3F5VC@33958,4HNBF@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family FFAGCILK_01110 543734.LCABL_26350 1.5e-184 652.1 Lactobacillaceae yxeA ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TVQ4@1239,3FBQ0@33958,4IRU4@91061,COG0577@1,COG0577@2 NA|NA|NA V FtsX-like permease family FFAGCILK_01111 543734.LCABL_26360 6.7e-125 453.4 Lactobacillaceae devA 3.6.3.25 ko:K02003,ko:K06020,ko:K09810 ko02010,map02010 M00255,M00258 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.125 Bacteria 1UYJ6@1239,3F5SR@33958,4HF89@91061,COG1136@1,COG1136@2 NA|NA|NA V ATPases associated with a variety of cellular activities FFAGCILK_01112 1423732.BALS01000005_gene1101 3.2e-33 147.1 Lactobacillaceae Bacteria 1U6KC@1239,29PH8@1,30AFD@2,3F83D@33958,4IGD6@91061 NA|NA|NA FFAGCILK_01113 543734.LCABL_26380 5.3e-112 410.6 Lactobacillaceae tipA ko:K21744 ko00000,ko03000 Bacteria 1TS6Z@1239,3FC68@33958,4HUDT@91061,COG0789@1,COG0789@2 NA|NA|NA K TipAS antibiotic-recognition domain FFAGCILK_01114 220668.lp_3080 1.4e-20 107.1 Lactobacillaceae M1-1017 Bacteria 1V9IF@1239,3F6UB@33958,4HKB8@91061,COG4858@1,COG4858@2 NA|NA|NA FFAGCILK_01115 1136177.KCA1_2522 2.4e-32 144.8 Lactobacillaceae ko:K10947 ko00000,ko03000 Bacteria 1VAGB@1239,3F70B@33958,4HKBS@91061,COG1695@1,COG1695@2 NA|NA|NA K Transcriptional regulator PadR-like family FFAGCILK_01116 543734.LCABL_26390 4.2e-138 497.3 Lactobacillaceae truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 ko00000,ko01000,ko03016 Bacteria 1TQUY@1239,3F4KC@33958,4HCFI@91061,COG0101@1,COG0101@2 NA|NA|NA J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs FFAGCILK_01117 543734.LCABL_26400 8.2e-140 503.1 Lactobacillaceae ecfT GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 ko:K02008,ko:K16783,ko:K16785 ko02010,map02010 M00245,M00246,M00581,M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TQ0E@1239,3F3UW@33958,4H9VT@91061,COG0619@1,COG0619@2 NA|NA|NA U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates FFAGCILK_01118 543734.LCABL_26410 6e-157 560.1 Lactobacillaceae ecfA2 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008144,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032217,GO:0032218,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035461,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0097159,GO:0097367,GO:0098656,GO:1901265,GO:1901363 3.6.3.55 ko:K02068,ko:K06857,ko:K16784,ko:K16786,ko:K16787 ko02010,map02010 M00186,M00211,M00581,M00582 R10531 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35,3.A.1.6.2,3.A.1.6.4 Bacteria 1TPH8@1239,3F48E@33958,4HA7T@91061,COG1122@1,COG1122@2 NA|NA|NA P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates FFAGCILK_01119 543734.LCABL_26420 1.6e-154 552.0 Lactobacillaceae ecfA1 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 ko:K16784,ko:K16786,ko:K16787 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TPH8@1239,3F3VD@33958,4H9R8@91061,COG1122@1,COG1122@2 NA|NA|NA P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates FFAGCILK_01120 543734.LCABL_26430 5.7e-118 430.3 Lactobacillaceae Bacteria 1U7Q7@1239,2BKGG@1,32EXB@2,3FA0B@33958,4IHMI@91061 NA|NA|NA FFAGCILK_01121 543734.LCABL_26440 4.8e-61 240.4 Lactobacillaceae rplQ GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02879,ko:K16193 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6JQ@1239,3F6GJ@33958,4HGX2@91061,COG0203@1,COG0203@2 NA|NA|NA J Ribosomal protein L17 FFAGCILK_01122 543734.LCABL_26450 3.6e-171 607.4 Lactobacillaceae rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1TPR8@1239,3F3W6@33958,4H9R1@91061,COG0202@1,COG0202@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates FFAGCILK_01123 543734.LCABL_26460 4e-63 247.3 Lactobacillaceae rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02948 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3IK@1239,3F67D@33958,4HH2T@91061,COG0100@1,COG0100@2 NA|NA|NA J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome FFAGCILK_01124 543734.LCABL_26470 4.7e-58 230.3 Lactobacillaceae rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02952 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3JH@1239,3F6GN@33958,4HGX6@91061,COG0099@1,COG0099@2 NA|NA|NA J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits FFAGCILK_01125 543734.LCABL_26480 6.6e-14 82.0 Lactobacillaceae rpmJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02919 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VK4F@1239,3F8TC@33958,4HR2X@91061,COG0257@1,COG0257@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL36 family FFAGCILK_01126 1423732.BALS01000005_gene1090 1.4e-33 148.3 Lactobacillaceae infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009986,GO:0016020,GO:0030246,GO:0030247,GO:0030312,GO:0040007,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071944,GO:2001065 ko:K02518 ko00000,ko03012 Bacteria 1V9ZK@1239,3F7CW@33958,4HKF4@91061,COG0361@1,COG0361@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex FFAGCILK_01127 543734.LCABL_26500 1.6e-120 438.7 Lactobacillaceae adk GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 iHN637.CLJU_RS20110 Bacteria 1TP27@1239,3F3KB@33958,4HA89@91061,COG0563@1,COG0563@2 NA|NA|NA F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism FFAGCILK_01128 543734.LCABL_26510 2e-231 808.1 Lactobacillaceae secY GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0040007,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5 Bacteria 1TPHB@1239,3F4FV@33958,4HAWH@91061,COG0201@1,COG0201@2 NA|NA|NA U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently FFAGCILK_01129 543734.LCABL_26520 6.5e-62 243.4 Lactobacillaceae rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02876 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3KE@1239,3F675@33958,4HFPW@91061,COG0200@1,COG0200@2 NA|NA|NA J Binds to the 23S rRNA FFAGCILK_01130 543734.LCABL_26530 3.9e-24 116.7 Lactobacillaceae rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02907 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEG4@1239,3F7ZU@33958,4HNHF@91061,COG1841@1,COG1841@2 NA|NA|NA J Ribosomal protein L30 FFAGCILK_01131 543734.LCABL_26540 1.2e-83 315.8 Lactobacillaceae rpsE GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02988 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1B1@1239,3F3VY@33958,4HFN4@91061,COG0098@1,COG0098@2 NA|NA|NA J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body FFAGCILK_01132 543734.LCABL_26550 1.8e-57 228.4 Lactobacillaceae rplR GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02881 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6DM@1239,3F6KN@33958,4HIGF@91061,COG0256@1,COG0256@2 NA|NA|NA J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance FFAGCILK_01133 543734.LCABL_26560 1.7e-93 348.6 Lactobacillaceae rplF GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02933 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1FC@1239,3F4G5@33958,4HFQD@91061,COG0097@1,COG0097@2 NA|NA|NA J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center FFAGCILK_01134 543734.LCABL_26570 1e-66 259.2 Lactobacillaceae rpsH GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010608,GO:0015935,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031329,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043487,GO:0043488,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903311,GO:1990904 ko:K02994 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3KK@1239,3F64E@33958,4HH32@91061,COG0096@1,COG0096@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit FFAGCILK_01135 1423816.BACQ01000060_gene2284 8.5e-96 356.3 Lactobacillaceae rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02931 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPE0@1239,3F3Q7@33958,4HBAX@91061,COG0094@1,COG0094@2 NA|NA|NA J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits FFAGCILK_01136 543734.LCABL_26590 1.4e-50 205.3 Lactobacillaceae rplX GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02895 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V9ZQ@1239,3F6X5@33958,4HKH9@91061,COG0198@1,COG0198@2 NA|NA|NA J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit FFAGCILK_01137 543734.LCABL_26600 2.1e-58 231.5 Lactobacillaceae rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02874 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3N0@1239,3F6GT@33958,4HGYR@91061,COG0093@1,COG0093@2 NA|NA|NA J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome FFAGCILK_01138 543734.LCABL_26610 1.9e-40 171.4 Lactobacillaceae rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02961 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V9YC@1239,3F7FX@33958,4HKDN@91061,COG0186@1,COG0186@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA FFAGCILK_01139 543734.LCABL_26620 1.1e-24 118.6 Lactobacillaceae rpmC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02904 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEME@1239,3F82Z@33958,4HNUP@91061,COG0255@1,COG0255@2 NA|NA|NA J Belongs to the universal ribosomal protein uL29 family FFAGCILK_01140 543734.LCABL_26630 2.3e-75 288.1 Lactobacillaceae rplP GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02878 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1AY@1239,3F653@33958,4HFPN@91061,COG0197@1,COG0197@2 NA|NA|NA J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs FFAGCILK_01141 543734.LCABL_26640 6.2e-109 400.2 Lactobacillaceae rpsC GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02982 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPCP@1239,3F3Q8@33958,4HAUR@91061,COG0092@1,COG0092@2 NA|NA|NA J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation FFAGCILK_01142 1423732.BALS01000005_gene1074 1.1e-54 219.2 Lactobacillaceae rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02890 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6PU@1239,3F6K6@33958,4HIK2@91061,COG0091@1,COG0091@2 NA|NA|NA J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome FFAGCILK_01143 1423732.BALS01000005_gene1073 2.2e-47 194.5 Lactobacillaceae rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02965 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6CX@1239,3F6XP@33958,4HIG0@91061,COG0185@1,COG0185@2 NA|NA|NA J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA FFAGCILK_01144 543734.LCABL_26670 2.9e-156 557.8 Lactobacillaceae rplB GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02886 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TP9X@1239,3F3XI@33958,4HAE8@91061,COG0090@1,COG0090@2 NA|NA|NA J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity FFAGCILK_01145 543734.LCABL_26680 2e-46 191.4 Lactobacillaceae rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02892 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VA4W@1239,3F6Z2@33958,4HKCV@91061,COG0089@1,COG0089@2 NA|NA|NA J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome FFAGCILK_01146 543734.LCABL_26690 1.7e-108 398.7 Lactobacillaceae rplD GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030312,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02926,ko:K16193 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPGW@1239,3F3QD@33958,4HB01@91061,COG0088@1,COG0088@2 NA|NA|NA J Forms part of the polypeptide exit tunnel FFAGCILK_01147 543734.LCABL_26700 4e-113 414.1 Lactobacillaceae rplC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 ko:K02906 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPFT@1239,3F45I@33958,4HAEN@91061,COG0087@1,COG0087@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit FFAGCILK_01148 543734.LCABL_26710 2e-49 201.4 Lactobacillaceae rpsJ GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 ko:K02946 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6C9@1239,3F6KC@33958,4HIKH@91061,COG0051@1,COG0051@2 NA|NA|NA J Involved in the binding of tRNA to the ribosomes FFAGCILK_01149 543734.LCABL_26720 6e-68 263.5 Bacilli psiE ko:K13256 ko00000 Bacteria 1V9CG@1239,4HIMW@91061,COG3223@1,COG3223@2 NA|NA|NA S Phosphate-starvation-inducible E FFAGCILK_01150 543734.LCABL_26730 5.5e-106 390.2 Lactobacillaceae ahpC 1.11.1.15 ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Bacteria 1TQU7@1239,3FCCT@33958,4HVUV@91061,COG0450@1,COG0450@2 NA|NA|NA O C-terminal domain of 1-Cys peroxiredoxin FFAGCILK_01151 543734.LCABL_26740 1.5e-197 695.3 Lactobacillaceae yfjR GO:0008150,GO:0043900,GO:0050789,GO:0050794,GO:0065007,GO:1900190 Bacteria 1VVQ0@1239,3FB7T@33958,4HW20@91061,COG2378@1,COG2378@2 NA|NA|NA K WYL domain FFAGCILK_01152 543734.LCABL_26750 0.0 1384.0 Lactobacillaceae fusA GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02355 ko00000,ko03012,ko03029 Bacteria 1TPF9@1239,3F3JR@33958,4HAB8@91061,COG0480@1,COG0480@2 NA|NA|NA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome FFAGCILK_01153 1423732.BALS01000083_gene2031 8.4e-84 316.2 Lactobacillaceae rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02992 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1GG@1239,3F3RX@33958,4H9PA@91061,COG0049@1,COG0049@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA FFAGCILK_01154 543734.LCABL_26770 1.2e-70 272.3 Lactobacillaceae rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02950 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1FJ@1239,3F64B@33958,4HFMZ@91061,COG0048@1,COG0048@2 NA|NA|NA J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit FFAGCILK_01155 543734.LCABL_26780 0.0 5084.6 Lactobacillaceae Bacteria 1TQBI@1239,3F7WQ@33958,4HBAT@91061,COG4932@1,COG4932@2 NA|NA|NA M domain protein FFAGCILK_01156 1423816.BACQ01000061_gene2309 4e-36 157.9 Lactobacillaceae 3.4.23.43 ko:K02236 M00429 ko00000,ko00002,ko01000,ko02044 Bacteria 1U7QC@1239,29Q94@1,30B88@2,3FA0H@33958,4IHMP@91061 NA|NA|NA FFAGCILK_01157 543734.LCABL_26800 0.0 2416.7 Lactobacillaceae rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1TNYT@1239,3F3KF@33958,4HA24@91061,COG0086@1,COG0086@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates FFAGCILK_01158 543734.LCABL_26820 0.0 2374.0 Lactobacillaceae rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1TP96@1239,3F4ET@33958,4H9PK@91061,COG0085@1,COG0085@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates FFAGCILK_01159 543734.LCABL_26830 0.0 1604.0 Lactobacillaceae clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 ko:K03696 ko01100,map01100 ko00000,ko03110 Bacteria 1TPMU@1239,3F3RV@33958,4HACY@91061,COG0542@1,COG0542@2 NA|NA|NA O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE FFAGCILK_01160 543734.LCABL_26840 4.3e-80 303.9 Lactobacillaceae ctsR GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 ko:K03708 ko00000,ko03000 Bacteria 1VAXT@1239,3F53E@33958,4HIFT@91061,COG4463@1,COG4463@2 NA|NA|NA K Belongs to the CtsR family FFAGCILK_01169 543734.LCABL_26990 6.6e-292 1009.2 Lactobacillaceae lysS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP2P@1239,3F439@33958,4H9X4@91061,COG1190@1,COG1190@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family FFAGCILK_01170 543734.LCABL_27000 1.2e-188 665.6 Lactobacillaceae dus ko:K05540 ko00000,ko01000,ko03016 Bacteria 1TQ2R@1239,3F4C6@33958,4HA9K@91061,COG0042@1,COG0042@2 NA|NA|NA J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines FFAGCILK_01171 543734.LCABL_27010 3.8e-162 577.4 Lactobacillaceae hslO GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0031647,GO:0036506,GO:0042026,GO:0042802,GO:0043167,GO:0043169,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0065007,GO:0065008 ko:K04083 ko00000,ko03110 Bacteria 1TRCH@1239,3F42B@33958,4HAFR@91061,COG1281@1,COG1281@2 NA|NA|NA O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress FFAGCILK_01172 543734.LCABL_27020 1e-162 579.3 Lactobacillaceae Bacteria 1U7E3@1239,29Q36@1,30B1U@2,3F9G9@33958,4IH9Z@91061 NA|NA|NA S WxL domain surface cell wall-binding FFAGCILK_01173 543734.LCABL_27040 3.3e-184 651.0 Lactobacillaceae Bacteria 1U765@1239,3F910@33958,4IH0X@91061,COG4072@1,COG4072@2 NA|NA|NA S Bacterial protein of unknown function (DUF916) FFAGCILK_01174 543734.LCABL_27050 2.2e-193 681.4 Lactobacillaceae Bacteria 1V92G@1239,3F9EF@33958,4HIJ2@91061,COG4072@1,COG4072@2 NA|NA|NA S Protein of unknown function C-terminal (DUF3324) FFAGCILK_01175 543734.LCABL_27060 0.0 1654.8 Lactobacillaceae Bacteria 1VUWY@1239,3F94G@33958,4HVSW@91061,COG4886@1,COG4886@2 NA|NA|NA S Leucine-rich repeat (LRR) protein FFAGCILK_01176 543734.LCABL_27070 0.0 1194.9 Lactobacillaceae ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 ko:K03798 M00742 ko00000,ko00002,ko01000,ko01002,ko03110 Bacteria 1TPTV@1239,3F49Z@33958,4HAJB@91061,COG0465@1,COG0465@2 NA|NA|NA O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins FFAGCILK_01177 543734.LCABL_27080 1.3e-96 359.0 Lactobacillaceae hpt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 Bacteria 1V1C9@1239,3F56C@33958,4HFZ2@91061,COG0634@1,COG0634@2 NA|NA|NA F Belongs to the purine pyrimidine phosphoribosyltransferase family FFAGCILK_01178 543734.LCABL_27090 4.2e-242 843.6 Lactobacillaceae tilS 6.3.4.19 ko:K04075 R09597 RC02633,RC02634 ko00000,ko01000,ko03016 Bacteria 1TPXP@1239,3F4GY@33958,4H9ZM@91061,COG0037@1,COG0037@2 NA|NA|NA J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine FFAGCILK_01179 543734.LCABL_27100 9.3e-70 269.6 Lactobacillaceae yabR ko:K07570,ko:K07571 ko00000 Bacteria 1V6FE@1239,3F6HV@33958,4HIKM@91061,COG1098@1,COG1098@2 NA|NA|NA J RNA binding FFAGCILK_01180 543734.LCABL_27110 1.1e-66 259.2 Bacteria divIC ko:K05589,ko:K13052 ko00000,ko03036 Bacteria COG2919@1,COG2919@2 NA|NA|NA D cell cycle FFAGCILK_01181 543734.LCABL_27120 2.7e-39 167.5 Lactobacillaceae yabO GO:0008150,GO:0040007 Bacteria 1VEI5@1239,3F7JX@33958,4HKJJ@91061,COG1188@1,COG1188@2 NA|NA|NA J S4 domain protein FFAGCILK_01182 543734.LCABL_27130 2.5e-281 974.2 Lactobacillaceae yabM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03328,ko:K06409 ko00000,ko02000 2.A.66.2,2.A.66.2.14 Bacteria 1TNYX@1239,3F4BV@33958,4HACG@91061,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein FFAGCILK_01183 543734.LCABL_27140 0.0 2279.2 Lactobacillaceae mfd ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPF1@1239,3F4KU@33958,4H9NB@91061,COG1197@1,COG1197@2 NA|NA|NA L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site FFAGCILK_01184 543734.LCABL_27150 3.6e-102 377.5 Lactobacillaceae pth GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 ko00000,ko01000,ko03012 Bacteria 1V3NB@1239,3F3VZ@33958,4HH2Z@91061,COG0193@1,COG0193@2 NA|NA|NA J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis FFAGCILK_01185 1423732.BALS01000035_gene246 4.1e-181 640.6 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1TPSY@1239,3F3RM@33958,4HB0Z@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily. LDH family FFAGCILK_01186 543734.LCABL_27170 1.5e-261 908.3 Lactobacillaceae Bacteria 1TQMA@1239,3F3QW@33958,4HDTN@91061,COG1376@1,COG1376@2 NA|NA|NA S Putative peptidoglycan binding domain FFAGCILK_01187 543734.LCABL_27210 2.3e-119 434.9 Lactobacillaceae Bacteria 1TR5G@1239,3F3JY@33958,4H9ZA@91061,COG0517@1,COG0517@2 NA|NA|NA S (CBS) domain FFAGCILK_01188 543734.LCABL_27220 4e-122 444.1 Lactobacillaceae yciB Bacteria 1V4KP@1239,3F6PH@33958,4HIBF@91061,COG1376@1,COG1376@2 NA|NA|NA M ErfK YbiS YcfS YnhG FFAGCILK_01189 543734.LCABL_27230 5.8e-285 986.1 Lactobacillaceae gltD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 iJN678.gltD,iNJ661.Rv3858c,iSB619.SA_RS02450 Bacteria 1TQ1A@1239,3FB6A@33958,4HAD5@91061,COG0493@1,COG0493@2 NA|NA|NA E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster FFAGCILK_01190 543734.LCABL_27240 0.0 2918.6 Lactobacillaceae gltB GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1,2.1.1.21 ko:K00265,ko:K00284,ko:K22083 ko00250,ko00630,ko00680,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00680,map00910,map01100,map01110,map01120,map01130,map01230 R00021,R00093,R00114,R00248,R01586,R10086 RC00006,RC00010,RC00554,RC02799 ko00000,ko00001,ko01000 iBWG_1329.BWG_2914,iECDH10B_1368.ECDH10B_3387,iECDH1ME8569_1439.EcDH1_0495,iEcDH1_1363.EcDH1_0495,iPC815.YPO3557 Bacteria 1TQ0B@1239,3F4TU@33958,4HA4G@91061,COG0067@1,COG0067@2,COG0069@1,COG0069@2,COG0070@1,COG0070@2 NA|NA|NA E GXGXG motif FFAGCILK_01191 543734.LCABL_27250 4.5e-86 323.9 Lactobacillaceae Bacteria 1V463@1239,3FCEF@33958,4HH0P@91061,COG4708@1,COG4708@2 NA|NA|NA S QueT transporter FFAGCILK_01192 543734.LCABL_27260 5.6e-62 243.4 Lactobacillaceae ndoA ko:K07171 ko00000,ko01000,ko02048 Bacteria 1V6DK@1239,3F6Y9@33958,4HGXF@91061,COG2337@1,COG2337@2 NA|NA|NA L Toxic component of a toxin-antitoxin (TA) module FFAGCILK_01193 1423816.BACQ01000044_gene1675 5.2e-32 143.3 Lactobacillaceae Bacteria 1U736@1239,29PVB@1,30ATJ@2,3F8WZ@33958,4IGXQ@91061 NA|NA|NA FFAGCILK_01194 543734.LCABL_27280 4.1e-217 760.4 Lactobacillaceae alr 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 R00401 RC00285 ko00000,ko00001,ko01000,ko01011 Bacteria 1TNYY@1239,3F3X2@33958,4HA95@91061,COG0787@1,COG0787@2 NA|NA|NA E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids FFAGCILK_01195 543734.LCABL_27290 8.5e-63 246.1 Lactobacillaceae acpS 2.7.6.3,2.7.8.7,5.1.1.1 ko:K00950,ko:K00997,ko:K01775 ko00473,ko00770,ko00790,ko01100,ko01502,map00473,map00770,map00790,map01100,map01502 M00126,M00841 R00401,R01625,R03503 RC00002,RC00017,RC00285 ko00000,ko00001,ko00002,ko01000,ko01011 iYO844.BSU04620 Bacteria 1VA0T@1239,3F6HC@33958,4HKBI@91061,COG0736@1,COG0736@2 NA|NA|NA I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein FFAGCILK_01196 543734.LCABL_27300 7e-265 919.5 Lactobacillaceae cshA GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 1TPAP@1239,3F46Q@33958,4HAB3@91061,COG0513@1,COG0513@2 NA|NA|NA F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity FFAGCILK_01197 543734.LCABL_27310 2.3e-262 911.0 Lactobacillaceae murF 6.3.2.10,6.3.2.13 ko:K01928,ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 R02788,R04573,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1VT78@1239,3F4SK@33958,4HACR@91061,COG0770@1,COG0770@2 NA|NA|NA M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein FFAGCILK_01198 543734.LCABL_27320 4e-144 517.3 Lactobacillaceae Bacteria 1V46E@1239,29SV9@1,30E1E@2,3F6E2@33958,4HI7R@91061 NA|NA|NA FFAGCILK_01199 568703.LGG_00891 8.3e-09 65.9 Lactobacillaceae Bacteria 1U8CV@1239,2BT3F@1,32N80@2,3FAUG@33958,4IIAU@91061 NA|NA|NA FFAGCILK_01200 543734.LCABL_27330 9.6e-123 446.0 Lactobacillaceae Bacteria 1VQ45@1239,3F62R@33958,4HRFF@91061,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat FFAGCILK_01201 543734.LCABL_27340 3.7e-125 454.1 Lactobacillaceae Bacteria 1V8QF@1239,2DNW7@1,32ZGM@2,3F601@33958,4HIIB@91061 NA|NA|NA FFAGCILK_01202 1423816.BACQ01000043_gene1667 1.2e-65 255.8 Lactobacillaceae Bacteria 1U7DP@1239,29Q2X@1,30B1I@2,3F9FK@33958,4IH9K@91061 NA|NA|NA FFAGCILK_01203 543734.LCABL_27360 2.5e-42 177.6 Lactobacillaceae rpmE2 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034224,GO:0034641,GO:0034645,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0120127,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02909 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEGU@1239,3F7D7@33958,4HKF0@91061,COG0254@1,COG0254@2 NA|NA|NA J Ribosomal protein L31 FFAGCILK_01204 543734.LCABL_27370 1.6e-235 821.6 Lactobacillaceae murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 R00660 RC00350 ko00000,ko00001,ko01000,ko01011 iYO844.BSU37100 Bacteria 1TPAU@1239,3F3P8@33958,4H9KI@91061,COG0766@1,COG0766@2 NA|NA|NA M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine FFAGCILK_01205 543734.LCABL_27380 0.0 1075.5 Lactobacillaceae pyrG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS01075,iNJ661.Rv1699 Bacteria 1TP34@1239,3F42X@33958,4H9X6@91061,COG0504@1,COG0504@2 NA|NA|NA F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates FFAGCILK_01206 543734.LCABL_27390 1.3e-157 562.4 Lactobacillaceae Bacteria 1VNI3@1239,3F5J9@33958,4HSHZ@91061,COG3548@1,COG3548@2 NA|NA|NA S Protein of unknown function (DUF1211) FFAGCILK_01207 543734.LCABL_27400 4.5e-54 218.0 Lactobacillaceae rpoE GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Bacteria 1V6WX@1239,3F55D@33958,4HIUK@91061,COG3343@1,COG3343@2 NA|NA|NA K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling FFAGCILK_01208 543734.LCABL_27410 1e-78 299.3 Lactobacillaceae ywiB Bacteria 1V8IZ@1239,3F6AI@33958,4HIW0@91061,COG4506@1,COG4506@2 NA|NA|NA S Domain of unknown function (DUF1934) FFAGCILK_01209 543734.LCABL_27420 1.5e-155 555.4 Lactobacillaceae lipL GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.200,2.3.1.204 ko:K16869,ko:K18821 ko00000,ko01000 Bacteria 1TQKA@1239,3F575@33958,4HCPS@91061,COG0095@1,COG0095@2 NA|NA|NA H biotin lipoate A B protein ligase FFAGCILK_01210 543734.LCABL_27430 7.1e-269 932.6 Lactobacillaceae ywfO GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 ko:K06885 ko00000 Bacteria 1TPVB@1239,3F442@33958,4HAX8@91061,COG1078@1,COG1078@2 NA|NA|NA S HD domain protein FFAGCILK_01211 1423816.BACQ01000037_gene1572 1.4e-80 305.4 Lactobacillaceae mutT 3.5.4.33,3.6.1.13,3.6.1.55 ko:K01515,ko:K03574,ko:K11991 ko00230,map00230 R01054,R10223 RC00002,RC00477 ko00000,ko00001,ko01000,ko03016,ko03400 Bacteria 1VD6I@1239,3F75N@33958,4HKRW@91061,COG0494@1,COG0494@2 NA|NA|NA L NUDIX domain FFAGCILK_01212 543734.LCABL_27450 7.5e-181 639.8 Lactobacillaceae Bacteria 1UR34@1239,3F4J5@33958,4HDF2@91061,COG1434@1,COG1434@2 NA|NA|NA S DUF218 domain FFAGCILK_01213 543734.LCABL_27460 2.1e-53 214.9 Lactobacillaceae mscL GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 ko:K03282 ko00000,ko02000 1.A.22.1 Bacteria 1VA14@1239,3F6YZ@33958,4HKIA@91061,COG1970@1,COG1970@2 NA|NA|NA M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell FFAGCILK_01214 543734.LCABL_27470 3e-79 301.2 Lactobacillaceae Bacteria 1TS2B@1239,3F5R6@33958,4HCID@91061,COG0786@1,COG0786@2 NA|NA|NA E glutamate:sodium symporter activity FFAGCILK_01215 543734.LCABL_27480 1.1e-53 215.7 Bacilli nudA Bacteria 1VEJD@1239,4HNU5@91061,COG4043@1,COG4043@2 NA|NA|NA S ASCH FFAGCILK_01216 1423816.BACQ01000037_gene1564 1.3e-176 625.5 Lactobacillaceae prs 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2848 Bacteria 1TQ6Q@1239,3F3U2@33958,4HB61@91061,COG0462@1,COG0462@2 NA|NA|NA F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) FFAGCILK_01217 543734.LCABL_27510 2.2e-217 761.5 Lactobacillaceae glmU GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030203,GO:0030260,GO:0033692,GO:0034637,GO:0034645,GO:0035635,GO:0040007,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042,ko:K11528 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP88@1239,3F4I3@33958,4H9V5@91061,COG1207@1,COG1207@2 NA|NA|NA M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain FFAGCILK_01218 543734.LCABL_27520 4e-223 780.4 Lactobacillaceae ysaA Bacteria 1V04Y@1239,3F3SH@33958,4HDS5@91061,COG4767@1,COG4767@2 NA|NA|NA V RDD family FFAGCILK_01219 543734.LCABL_27530 1e-151 542.7 Lactobacillaceae purR 2.4.2.22,2.4.2.7 ko:K00759,ko:K03816,ko:K09685 ko00230,ko01100,ko01110,map00230,map01100,map01110 R00190,R01229,R02142,R04378 RC00063,RC00122 ko00000,ko00001,ko01000,ko03000,ko04147 Bacteria 1TPN9@1239,3F3NH@33958,4HB8I@91061,COG0503@1,COG0503@2 NA|NA|NA F pur operon repressor FFAGCILK_01220 543734.LCABL_27540 1.5e-118 432.2 Lactobacillaceae ybbL GO:0005575,GO:0005623,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0016020,GO:0019725,GO:0030003,GO:0042592,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071944,GO:0098771 ko:K02065,ko:K02068 ko02010,map02010 M00210,M00211,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 1V3DQ@1239,3F4UY@33958,4HHGU@91061,COG4619@1,COG4619@2 NA|NA|NA S ABC transporter, ATP-binding protein FFAGCILK_01221 543734.LCABL_27550 9e-120 436.4 Lactobacillaceae ybbM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 ko:K02069 M00211 ko00000,ko00002,ko02000 9.B.25.1 Bacteria 1UY1N@1239,3F4P1@33958,4HDM4@91061,COG0390@1,COG0390@2 NA|NA|NA S Uncharacterised protein family (UPF0014) FFAGCILK_01222 543734.LCABL_27560 1.3e-159 568.9 Lactobacillaceae czcD ko:K16264 ko00000,ko02000 2.A.4.1 Bacteria 1TR92@1239,3F4KJ@33958,4HBCQ@91061,COG1230@1,COG1230@2 NA|NA|NA P cation diffusion facilitator family transporter FFAGCILK_01223 543734.LCABL_27570 1.7e-179 635.2 Lactobacillaceae ispE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.1.1.182,2.7.1.148 ko:K00919,ko:K02528,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096,M00582 R05634,R10716 RC00002,RC00003,RC01439,RC03257 ko00000,ko00001,ko00002,ko01000,ko02000,ko03009 3.A.1.29 iEC55989_1330.EC55989_1304,iLJ478.TM1383,iYO844.BSU00460 Bacteria 1TPXV@1239,3F43W@33958,4HAV8@91061,COG1947@1,COG1947@2 NA|NA|NA F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol FFAGCILK_01224 543734.LCABL_27580 1.1e-37 162.2 Lactobacillaceae veg Bacteria 1VEQM@1239,3F7D3@33958,4HKF8@91061,COG4466@1,COG4466@2 NA|NA|NA S Biofilm formation stimulator VEG FFAGCILK_01225 543734.LCABL_27590 7.5e-158 563.1 Lactobacillaceae ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 R10716 RC00003,RC03257 ko00000,ko01000,ko03009 Bacteria 1TP9W@1239,3F3VC@33958,4HA4R@91061,COG0030@1,COG0030@2 NA|NA|NA J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits FFAGCILK_01226 543734.LCABL_27600 1.3e-99 369.0 Lactobacillaceae rnmV GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 ko:K05985,ko:K07476 ko00000,ko01000 Bacteria 1V3K3@1239,3F64F@33958,4HH5Y@91061,COG1658@1,COG1658@2 NA|NA|NA J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step FFAGCILK_01227 543734.LCABL_27610 3.6e-148 530.8 Lactobacillaceae tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 ko:K03424 ko00000,ko01000 Bacteria 1TNY1@1239,3F3N2@33958,4HA74@91061,COG0084@1,COG0084@2 NA|NA|NA L hydrolase, TatD family FFAGCILK_01228 543734.LCABL_27620 2.2e-79 301.6 Bacteria manR 2.7.1.194,2.7.1.200,2.7.1.202,2.7.1.204 ko:K02538,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 M00273,M00279,M00283,M00306,M00550,M00807 R03232,R05570,R07671,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1,4.A.5,4.A.5.1,4.A.7.1 Bacteria COG1762@1,COG1762@2 NA|NA|NA G phosphoenolpyruvate-dependent sugar phosphotransferase system FFAGCILK_01229 543734.LCABL_27630 5e-187 660.2 Lactobacillaceae yihT GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0034308,GO:0042180,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0061595,GO:0061720,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1901615,GO:1902776,GO:1902777 4.1.2.40,4.1.2.57 ko:K01635,ko:K01671 ko00052,ko01100,ko02024,map00052,map01100,map02024 R01069,R10760 RC00438,RC00439 ko00000,ko00001,ko01000 Bacteria 1TQRR@1239,3F3UA@33958,4HBS9@91061,COG3684@1,COG3684@2 NA|NA|NA G Belongs to the aldolase LacD family FFAGCILK_01230 543734.LCABL_27640 6.9e-172 609.8 Lactobacillaceae yqhA Bacteria 1V3WP@1239,3F5RU@33958,4HHIH@91061,COG2017@1,COG2017@2 NA|NA|NA G Aldose 1-epimerase FFAGCILK_01231 543734.LCABL_27650 1.3e-120 439.1 Lactobacillaceae Bacteria 1TRDQ@1239,3FC2V@33958,4HP0H@91061,COG3279@1,COG3279@2 NA|NA|NA T LytTr DNA-binding domain FFAGCILK_01232 543734.LCABL_27660 3e-138 498.0 Bacilli 2.7.13.3 ko:K02476,ko:K07706 ko02020,ko02024,map02020,map02024 M00495 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1UZ9P@1239,4HQIT@91061,COG3290@1,COG3290@2 NA|NA|NA T GHKL domain FFAGCILK_01233 543734.LCABL_27670 0.0 1152.1 Lactobacillaceae ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TPZP@1239,3F604@33958,4HDMH@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter FFAGCILK_01234 543734.LCABL_27680 0.0 1166.4 Lactobacillaceae ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TPZP@1239,3F53S@33958,4HDMH@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter FFAGCILK_01235 543734.LCABL_27690 0.0 1332.4 Lactobacillaceae metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPA1@1239,3F3XR@33958,4H9VC@91061,COG0143@1,COG0143@2 NA|NA|NA J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation FFAGCILK_01236 543734.LCABL_27700 5.6e-174 616.7 Lactobacillaceae pepI 3.4.11.5,3.5.1.101 ko:K01259,ko:K18457 ko00330,map00330 R00135 ko00000,ko00001,ko01000,ko01002 Bacteria 1TRMT@1239,3F40N@33958,4HE23@91061,COG2267@1,COG2267@2 NA|NA|NA E Releases the N-terminal proline from various substrates FFAGCILK_01237 543734.LCABL_27710 3e-153 547.7 Lactobacillaceae yunF Bacteria 1TPX4@1239,3F40Y@33958,4HA0X@91061,COG1801@1,COG1801@2 NA|NA|NA F Protein of unknown function DUF72 FFAGCILK_01238 543734.LCABL_27720 3.8e-92 344.0 Lactobacillaceae 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 1VAC7@1239,3F7HC@33958,4HKN6@91061,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain FFAGCILK_01239 543734.LCABL_27730 6e-171 606.7 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1UXY2@1239,3F4M2@33958,4HD1S@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily FFAGCILK_01240 543734.LCABL_27740 1.6e-106 392.1 Lactobacillaceae yiiE Bacteria 1VAQZ@1239,3F6Q5@33958,4HJFH@91061,COG3548@1,COG3548@2 NA|NA|NA S Protein of unknown function (DUF1211) FFAGCILK_01241 543734.LCABL_27750 2.8e-128 464.5 Lactobacillaceae cobB ko:K12410 ko00000,ko01000 Bacteria 1TQKD@1239,3FC3Y@33958,4HGHS@91061,COG0846@1,COG0846@2 NA|NA|NA K Sir2 family FFAGCILK_01242 543734.LCABL_27760 1.4e-16 91.3 Lactobacillaceae Bacteria 1U8GG@1239,29QQH@1,30BQA@2,3FAYF@33958,4IIE9@91061 NA|NA|NA FFAGCILK_01243 543734.LCABL_27770 4.2e-172 610.5 Lactobacillaceae Bacteria 1VT7R@1239,296WI@1,2ZU5A@2,3F4R1@33958,4HVBN@91061 NA|NA|NA FFAGCILK_01245 543734.LCABL_27780 2.1e-96 358.2 Lactobacillaceae yxkA ko:K06910 ko00000 Bacteria 1VJEE@1239,3F75J@33958,4HXTJ@91061,COG1881@1,COG1881@2 NA|NA|NA S Phosphatidylethanolamine-binding protein FFAGCILK_01246 1423734.JCM14202_1668 3.6e-18 97.4 Lactobacillaceae Bacteria 1U6QJ@1239,29BUI@1,2ZYSU@2,3F8B7@33958,4IGHU@91061 NA|NA|NA FFAGCILK_01247 1423732.BALS01000010_gene1903 5.1e-150 537.3 Lactobacillaceae ypuA Bacteria 1TR2I@1239,3FBNF@33958,4HBVZ@91061,COG4086@1,COG4086@2 NA|NA|NA S Protein of unknown function (DUF1002) FFAGCILK_01248 543734.LCABL_27810 2.7e-174 617.8 Lactobacillaceae ppx 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 1TS3I@1239,3F3SR@33958,4HAQS@91061,COG0248@1,COG0248@2 NA|NA|NA FP exopolyphosphatase FFAGCILK_01249 543734.LCABL_27820 0.0 1419.1 Lactobacillaceae ppk GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 iJN746.PP_5217 Bacteria 1TNZM@1239,3F3PE@33958,4HA88@91061,COG0855@1,COG0855@2 NA|NA|NA P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) FFAGCILK_01250 543734.LCABL_27830 2.1e-285 987.6 Lactobacillaceae ppx3 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 1VT8Q@1239,3F49N@33958,4HB84@91061,COG0248@1,COG0248@2 NA|NA|NA FP exopolyphosphatase FFAGCILK_01251 543734.LCABL_27840 6.4e-176 623.2 Lactobacillaceae Bacteria 1TQ12@1239,3F4U1@33958,4HA57@91061,COG4989@1,COG4989@2 NA|NA|NA S Aldo keto reductase FFAGCILK_01252 543734.LCABL_27850 2.1e-154 551.6 Bacilli Bacteria 1UIXT@1239,4ISW5@91061,COG0500@1,COG2226@2 NA|NA|NA Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FFAGCILK_01253 543734.LCABL_27860 4e-92 344.0 Lactobacillaceae ywnH GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 Bacteria 1V3V3@1239,3F70T@33958,4HHNY@91061,COG1247@1,COG1247@2 NA|NA|NA M Acetyltransferase (GNAT) domain FFAGCILK_01254 543734.LCABL_27870 6.3e-241 839.7 Lactobacillaceae dinF Bacteria 1TNZN@1239,3FC3X@33958,4HANM@91061,COG0534@1,COG0534@2 NA|NA|NA V MatE FFAGCILK_01255 543734.LCABL_27880 1.9e-110 405.6 Lactobacillaceae ko:K06872,ko:K07507 ko00000,ko02000 9.B.20 Bacteria 1V5YF@1239,3F5HD@33958,4HJVB@91061,COG1512@1,COG1512@2 NA|NA|NA S TPM domain FFAGCILK_01256 543734.LCABL_27890 1e-102 379.4 Lactobacillaceae lemA ko:K03744 ko00000 Bacteria 1V3Z0@1239,3FCF0@33958,4HH6X@91061,COG1704@1,COG1704@2 NA|NA|NA S LemA family FFAGCILK_01257 543734.LCABL_27900 1.6e-193 681.8 Lactobacillaceae trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPY7@1239,3F3V6@33958,4HA1K@91061,COG0180@1,COG0180@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family FFAGCILK_01258 543734.LCABL_27920 1.8e-142 511.9 Bacteria Bacteria COG0577@1,COG0577@2 NA|NA|NA V efflux transmembrane transporter activity FFAGCILK_01259 543734.LCABL_27930 1.3e-163 582.8 Lactobacillaceae ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TNZG@1239,3F9SY@33958,4H9UT@91061,COG1136@1,COG1136@2 NA|NA|NA V ATPases associated with a variety of cellular activities FFAGCILK_01260 543734.LCABL_27950 5.1e-72 276.9 Lactobacillaceae gshR 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 Bacteria 1TS0Z@1239,3F3K2@33958,4HBYB@91061,COG1249@1,COG1249@2 NA|NA|NA C Glutathione reductase FFAGCILK_01261 543734.LCABL_27960 1.3e-176 625.5 Lactobacillaceae proV ko:K05847 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 1TPV8@1239,3F55H@33958,4H9SI@91061,COG1125@1,COG1125@2 NA|NA|NA E ABC transporter, ATP-binding protein FFAGCILK_01262 543734.LCABL_27970 2e-275 954.5 Lactobacillaceae proWX ko:K05845,ko:K05846 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 1TQ7D@1239,3F44S@33958,4HBDR@91061,COG1174@1,COG1174@2,COG1732@1,COG1732@2 NA|NA|NA EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) FFAGCILK_01264 543734.LCABL_27980 0.0 1448.0 Lactobacillaceae helD 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TP39@1239,3F486@33958,4H9Y5@91061,COG3973@1,COG3973@2 NA|NA|NA L DNA helicase FFAGCILK_01265 543734.LCABL_27990 4.5e-149 533.9 Lactobacillaceae rlrG ko:K21900 ko00000,ko03000 Bacteria 1TP6T@1239,3F4VC@33958,4HC4T@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator FFAGCILK_01266 543734.LCABL_28000 1.8e-173 615.1 Lactobacillaceae shetA ko:K03304,ko:K11041 ko05150,map05150 ko00000,ko00001,ko02000,ko02042 2.A.16,2.A.16.1 Bacteria 1UYTE@1239,3FBRC@33958,4HGBI@91061,COG1275@1,COG1275@2 NA|NA|NA P Voltage-dependent anion channel FFAGCILK_01267 543734.LCABL_28010 2.8e-114 417.9 Lactobacillaceae ko:K07052 ko00000 Bacteria 1VFRX@1239,3F4Q0@33958,4HRQQ@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity FFAGCILK_01269 543734.LCABL_28030 3.1e-116 424.5 Lactobacillaceae ypgQ ko:K06950 ko00000 Bacteria 1V7IZ@1239,3F3PN@33958,4HIVB@91061,COG1418@1,COG1418@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. FFAGCILK_01270 543734.LCABL_28040 1.8e-69 268.5 Lactobacillaceae Bacteria 1U7IQ@1239,29Q5J@1,30B4H@2,3F9S0@33958,4IHFG@91061 NA|NA|NA K MarR family FFAGCILK_01271 543734.LCABL_28050 0.0 1667.9 Lactobacillaceae uvrA3 ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TP0A@1239,3FC8R@33958,4HTKA@91061,COG0178@1,COG0178@2 NA|NA|NA L excinuclease ABC FFAGCILK_01272 543734.LCABL_28060 3.6e-193 680.6 Lactobacillaceae yghZ ko:K19265 ko00000,ko01000 Bacteria 1TRS0@1239,3F414@33958,4HAZ2@91061,COG0667@1,COG0667@2 NA|NA|NA C Aldo keto reductase family protein FFAGCILK_01273 543734.LCABL_28070 1.1e-144 519.2 Lactobacillaceae Bacteria 1V8IN@1239,3F5CU@33958,4HJUX@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase FFAGCILK_01274 543734.LCABL_28080 8.1e-60 236.1 Lactobacillaceae Bacteria 1U708@1239,29PSZ@1,30AR5@2,3F8T2@33958,4IGUJ@91061 NA|NA|NA FFAGCILK_01275 1074451.CRL705_1431 4.1e-11 73.9 Lactobacillaceae Bacteria 1U6CF@1239,2DKPT@1,30A91@2,3F7KP@33958,4IG44@91061 NA|NA|NA FFAGCILK_01276 543734.LCABL_28100 3e-106 391.3 Lactobacillaceae yoaK Bacteria 1V1VQ@1239,3F5F5@33958,4HM4F@91061,COG3619@1,COG3619@2 NA|NA|NA S Protein of unknown function (DUF1275) FFAGCILK_01277 543734.LCABL_28110 1.9e-124 451.8 Lactobacillaceae yjhF Bacteria 1VDCB@1239,3FC5R@33958,4HJ9X@91061,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family FFAGCILK_01278 543734.LCABL_28120 3e-153 547.7 Lactobacillaceae yitU 3.1.3.104 ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R07280 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TREF@1239,3F47B@33958,4H9Y9@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase FFAGCILK_01279 543734.LCABL_28130 4.4e-88 330.5 Lactobacillaceae rnhA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1V4A0@1239,3F3RG@33958,4HHJ9@91061,COG0328@1,COG0328@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids FFAGCILK_01280 543734.LCABL_28140 1.7e-165 588.6 Lactobacillaceae Bacteria 1TP9T@1239,3F4HW@33958,4HCXX@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain FFAGCILK_01281 543734.LCABL_28150 3.5e-227 793.9 Lactobacillaceae Bacteria 1TPS5@1239,3F4AH@33958,4H9M3@91061,COG1167@1,COG1167@2 NA|NA|NA EK Aminotransferase, class I FFAGCILK_01282 543734.LCABL_28180 4.9e-181 640.6 Lactobacillaceae recA GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043142,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 ko:K03553 ko03440,map03440 M00729 ko00000,ko00001,ko00002,ko03400 Bacteria 1TPD5@1239,3F3KU@33958,4HAG5@91061,COG0468@1,COG0468@2 NA|NA|NA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage FFAGCILK_01283 543734.LCABL_28190 3.5e-118 431.0 Lactobacillaceae ydfK ko:K07150 ko00000 Bacteria 1UH19@1239,3FB62@33958,4HB4E@91061,COG1811@1,COG1811@2 NA|NA|NA S Protein of unknown function (DUF554) FFAGCILK_01284 543734.LCABL_28200 2.3e-89 334.7 Lactobacillaceae Bacteria 1U76S@1239,29P3K@1,30AWC@2,3F91T@33958,4IH1K@91061 NA|NA|NA FFAGCILK_01285 1033837.WANG_1733 1.3e-81 308.9 Lactobacillaceae tnp2PF3 Bacteria 1VTEC@1239,3F62D@33958,4HUXQ@91061,COG3293@1,COG3293@2 NA|NA|NA L Transposase DDE domain FFAGCILK_01286 203123.OEOE_0334 2.4e-58 231.1 Leuconostocaceae tnp2PF3 Bacteria 1VW4T@1239,4AYJV@81850,4HWBF@91061,COG3293@1,COG3293@2 NA|NA|NA L Putative transposase of IS4/5 family (DUF4096) FFAGCILK_01287 543734.LCABL_28210 0.0 1260.4 Lactobacillaceae fruA 2.7.1.194,2.7.1.200,2.7.1.202,2.7.1.204 ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 M00273,M00279,M00283,M00306,M00550,M00807 R03232,R05570,R07671,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1,4.A.5,4.A.5.1,4.A.7.1 Bacteria 1TPKU@1239,3F5D3@33958,4H9KR@91061,COG1299@1,COG1299@2,COG1445@1,COG1445@2,COG1762@1,COG1762@2 NA|NA|NA GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 FFAGCILK_01288 543734.LCABL_28220 2.9e-173 614.4 Lactobacillaceae pfkB 2.7.1.11,2.7.1.144,2.7.1.56 ko:K00882,ko:K00917,ko:K16370 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00345 R00756,R02071,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TTI9@1239,3F537@33958,4HCRN@91061,COG1105@1,COG1105@2 NA|NA|NA H pfkB family carbohydrate kinase FFAGCILK_01289 543734.LCABL_28230 2.8e-129 468.0 Lactobacillaceae rpl Bacteria 1TP26@1239,3F681@33958,4HDKG@91061,COG1737@1,COG1737@2 NA|NA|NA K Helix-turn-helix domain, rpiR family FFAGCILK_01290 543734.LCABL_28240 3.6e-293 1013.4 Lactobacillaceae glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 Bacteria 1TPX3@1239,3F3WI@33958,4H9ZF@91061,COG0554@1,COG0554@2 NA|NA|NA F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate FFAGCILK_01291 543734.LCABL_28260 1.5e-135 488.8 Lactobacillaceae ko:K03710 ko00000,ko03000 Bacteria 1VCJ9@1239,3F6DC@33958,4HM7V@91061,COG2188@1,COG2188@2 NA|NA|NA K UTRA domain FFAGCILK_01292 543734.LCABL_28270 4e-250 870.2 Lactobacillaceae fucA 3.2.1.51 ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 GH29 Bacteria 1TQH2@1239,3F4YW@33958,4HDR0@91061,COG3669@1,COG3669@2 NA|NA|NA G Alpha-L-fucosidase FFAGCILK_01293 543734.LCABL_28280 1.1e-162 579.3 Lactobacillaceae 2.7.1.191 ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 Bacteria 1TQJ4@1239,3FBI1@33958,4HIM5@91061,COG2893@1,COG2893@2,COG3444@1,COG3444@2 NA|NA|NA G PTS system sorbose subfamily IIB component FFAGCILK_01294 543734.LCABL_28290 1.4e-126 459.1 Lactobacillaceae ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 Bacteria 1UYP8@1239,3FC9E@33958,4HFQS@91061,COG3715@1,COG3715@2 NA|NA|NA G PTS system sorbose-specific iic component FFAGCILK_01295 543734.LCABL_28300 4.5e-149 533.9 Lactobacillaceae ko:K02747,ko:K02796,ko:K02815,ko:K17467 ko00030,ko00051,ko00052,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00052,map00520,map01100,map01120,map02060 M00276,M00277,M00278,M00610 R02630,R04076,R08366,R10407 RC00017,RC01069,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.17,4.A.6.1.3,4.A.6.1.4 Bacteria 1UMKU@1239,3FBHN@33958,4HCQB@91061,COG3716@1,COG3716@2 NA|NA|NA G PTS system mannose/fructose/sorbose family IID component FFAGCILK_01296 543734.LCABL_28310 3.3e-47 194.1 Lactobacillaceae chbA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0009987,GO:0015144,GO:0016043,GO:0016740,GO:0016772,GO:0016773,GO:0022607,GO:0022804,GO:0022857,GO:0034219,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0071702,GO:0071840,GO:0090563,GO:0090566,GO:1901264,GO:1902815 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 iECABU_c1320.ECABU_c17610,iECOK1_1307.ECOK1_1683,iECUMN_1333.ECUMN_2025,iNRG857_1313.NRG857_07575,iUMN146_1321.UM146_09345 Bacteria 1VEGE@1239,3F7SW@33958,4HM37@91061,COG1447@1,COG1447@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIA subunit FFAGCILK_01297 543734.LCABL_28320 5.9e-49 199.9 Lactobacillaceae 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 Bacteria 1VADE@1239,3F77Q@33958,4HKG9@91061,COG1440@1,COG1440@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit FFAGCILK_01298 543734.LCABL_28330 2.3e-289 1000.7 Lactobacillaceae bgl 3.2.1.21,3.2.1.86 ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 R00026,R00839,R02558,R02887,R02985,R03527,R04949,R04998,R05133,R05134,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3FC7B@33958,4H9KU@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family FFAGCILK_01299 543734.LCABL_28340 5.8e-155 553.5 Lactobacillaceae ypbG 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1UZ80@1239,3FBD4@33958,4HD5J@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family FFAGCILK_01300 543734.LCABL_28350 8.7e-248 862.4 Lactobacillaceae ko:K09704 ko00000 Bacteria 1TRJI@1239,3F535@33958,4HBQW@91061,COG3538@1,COG3538@2 NA|NA|NA S Metal-independent alpha-mannosidase (GH125) FFAGCILK_01301 543734.LCABL_28360 0.0 1756.1 Lactobacillaceae mngB 3.2.1.170 ko:K15524 ko00000,ko01000 GH38 Bacteria 1TQEH@1239,3F4XS@33958,4HBC7@91061,COG0383@1,COG0383@2 NA|NA|NA G Glycosyl hydrolases family 38 N-terminal domain FFAGCILK_01302 543734.LCABL_28370 1.5e-239 835.1 Lactobacillaceae GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016310,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0071704 2.7.1.207 ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 M00275,M00281 R04393,R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.1,4.A.3.2 Bacteria 1TSXJ@1239,3F5IS@33958,4HU65@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane FFAGCILK_01303 543734.LCABL_28380 7.2e-135 486.5 Lactobacillaceae ko:K03486,ko:K03492,ko:K03710 ko00000,ko03000 Bacteria 1TTCD@1239,3F4DA@33958,4HEXQ@91061,COG2188@1,COG2188@2 NA|NA|NA K UbiC transcription regulator-associated domain protein FFAGCILK_01304 543734.LCABL_28390 1e-136 492.7 Lactobacillaceae araD 4.1.2.17,5.1.3.4 ko:K01628,ko:K03077 ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120 M00550 R02262,R05850 RC00603,RC00604,RC01479 ko00000,ko00001,ko00002,ko01000 Bacteria 1V57Z@1239,3FCAV@33958,4HGYY@91061,COG0235@1,COG0235@2 NA|NA|NA G Class II Aldolase and Adducin N-terminal domain FFAGCILK_01306 543734.LCABL_28410 5.3e-247 860.1 Lactobacillaceae pts36C ko:K02775,ko:K20114 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279,M00807 R05570,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.5,4.A.5.1 Bacteria 1TQ10@1239,3FCCE@33958,4HAIT@91061,COG3775@1,COG3775@2 NA|NA|NA G PTS system sugar-specific permease component FFAGCILK_01307 543734.LCABL_28420 2.2e-51 208.0 Lactobacillaceae sgcB 2.7.1.194,2.7.1.200,2.7.1.204 ko:K02774,ko:K02822,ko:K20113 ko00052,ko00053,ko01100,ko01120,ko02060,map00052,map00053,map01100,map01120,map02060 M00279,M00283,M00550,M00807 R05570,R07671,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5,4.A.5.1,4.A.7.1 Bacteria 1VAU7@1239,3F7JF@33958,4IR9X@91061,COG3414@1,COG3414@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit FFAGCILK_01308 543734.LCABL_28430 5.6e-83 313.5 Lactobacillaceae pts36A 2.7.1.194,2.7.1.200,2.7.1.202,2.7.1.204 ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 M00273,M00279,M00283,M00306,M00550,M00807 R03232,R05570,R07671,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1,4.A.5,4.A.5.1,4.A.7.1 Bacteria 1VAHC@1239,3F7U5@33958,4HPPC@91061,COG1762@1,COG1762@2 NA|NA|NA G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 FFAGCILK_01309 543734.LCABL_28440 3e-142 511.1 Lactobacillaceae ko:K02444 ko00000,ko03000 Bacteria 1V1VH@1239,3FC5U@33958,4HG12@91061,COG1349@1,COG1349@2 NA|NA|NA K DeoR C terminal sensor domain FFAGCILK_01310 543734.LCABL_28450 4.3e-163 580.5 Lactobacillaceae Bacteria 1UM09@1239,3F5VI@33958,4ITNI@91061,COG1092@1,COG1092@2 NA|NA|NA J Methyltransferase domain FFAGCILK_01311 543734.LCABL_28460 0.0 1155.6 Lactobacillaceae 3.2.1.10 ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13 Bacteria 1TP53@1239,3F41I@33958,4HA1G@91061,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain protein FFAGCILK_01313 543734.LCABL_28650 7.9e-117 426.4 Lactobacillaceae alkD Bacteria 1V4WB@1239,3F4B1@33958,4HFXG@91061,COG4912@1,COG4912@2 NA|NA|NA L DNA alkylation repair enzyme FFAGCILK_01314 543734.LCABL_28660 2.2e-125 454.9 Lactobacillaceae rpiA GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,5.3.1.6 ko:K00851,ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056,R01737 RC00002,RC00017,RC00434 ko00000,ko00001,ko00002,ko01000 Bacteria 1V1DB@1239,3F43N@33958,4HFQ7@91061,COG0120@1,COG0120@2 NA|NA|NA G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate FFAGCILK_01315 543734.LCABL_28670 0.0 1231.5 Lactobacillaceae Bacteria 1UYWB@1239,3F5AG@33958,4HTZD@91061,COG1807@1,COG1807@2 NA|NA|NA M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family FFAGCILK_01316 543734.LCABL_28680 4.8e-171 607.1 Lactobacillaceae ykoT ko:K20534 ko00000,ko01000,ko01005,ko02000 4.D.2.1.9 GT2 Bacteria 1TPR3@1239,3F3X7@33958,4HC2Z@91061,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase family 2 FFAGCILK_01317 543734.LCABL_28690 4e-116 424.1 Lactobacillaceae lssY 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 1VY85@1239,3F4DD@33958,4HXM4@91061,COG0671@1,COG0671@2 NA|NA|NA I phosphatase FFAGCILK_01318 543734.LCABL_28700 5.2e-116 423.7 Lactobacillaceae dedA ko:K03975 ko00000 Bacteria 1UZ4P@1239,3F4KG@33958,4HG3F@91061,COG0586@1,COG0586@2 NA|NA|NA S SNARE-like domain protein FFAGCILK_01319 543734.LCABL_28710 8.4e-126 457.2 Lactobacillaceae Bacteria 1VU2I@1239,3F475@33958,4HHZT@91061,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor FFAGCILK_01320 543734.LCABL_28730 8.3e-273 945.7 Lactobacillaceae 3.2.1.122,3.2.1.86 ko:K01222,ko:K01232 ko00010,ko00500,map00010,map00500 R00837,R00838,R00839,R05133,R05134,R06113 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GH4,GT4 Bacteria 1TQ9I@1239,3F4W5@33958,4H9TM@91061,COG1486@1,COG1486@2 NA|NA|NA G Family 4 glycosyl hydrolase C-terminal domain FFAGCILK_01321 543734.LCABL_28740 4e-295 1020.0 Lactobacillaceae 2.7.1.199,2.7.1.208,2.7.1.211 ko:K02755,ko:K02756,ko:K02757,ko:K02790,ko:K02791,ko:K02809,ko:K02810 ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060 M00266,M00269,M00271 R00811,R02738,R04111 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.3,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9 Bacteria 1TPJ8@1239,3F44V@33958,4HA8X@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2 NA|NA|NA G phosphotransferase system, EIIB FFAGCILK_01322 543734.LCABL_28750 0.0 1932.1 Lactobacillaceae 4.2.2.1 ko:K01727 ko00000,ko01000 PL8 Bacteria 1TQ2K@1239,3F9RZ@33958,4HBG8@91061,COG5492@1,COG5492@2 NA|NA|NA N Polysaccharide lyase family 8, N terminal alpha-helical domain FFAGCILK_01324 543734.LCABL_28760 1.5e-30 138.3 Bacilli Bacteria 1VVQM@1239,2DVNR@1,33WIQ@2,4HWSH@91061 NA|NA|NA FFAGCILK_01325 543734.LCABL_28760 0.0 1081.6 Bacilli Bacteria 1VVQM@1239,2DVNR@1,33WIQ@2,4HWSH@91061 NA|NA|NA FFAGCILK_01327 543734.LCABL_28810 7e-110 403.3 Bacilli Bacteria 1VWJ1@1239,2F49V@1,33X0H@2,4HWUD@91061 NA|NA|NA FFAGCILK_01328 543734.LCABL_28820 8.9e-87 326.2 Bacilli Bacteria 1TYZ0@1239,2DJFW@1,305ZW@2,4HW93@91061 NA|NA|NA FFAGCILK_01329 543734.LCABL_28830 4.9e-138 498.0 Bacilli mga ko:K02538 ko00000,ko03000 Bacteria 1V9WD@1239,4HJD0@91061,COG3711@1,COG3711@2 NA|NA|NA K M protein trans-acting positive regulator FFAGCILK_01330 543734.LCABL_28870 1.4e-117 429.1 Lactobacillaceae Bacteria 1TR75@1239,3F6Y6@33958,4HJU7@91061,COG1737@1,COG1737@2 NA|NA|NA K Helix-turn-helix domain, rpiR family FFAGCILK_01331 543734.LCABL_28880 1.5e-83 315.5 Lactobacillaceae pts23A ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1 Bacteria 1VAEB@1239,3FC0X@33958,4HIPR@91061,COG2190@1,COG2190@2 NA|NA|NA G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 FFAGCILK_01334 768486.EHR_05290 6.1e-67 260.4 Enterococcaceae Bacteria 1V6J7@1239,4B1KC@81852,4HHPU@91061,COG0432@1,COG0432@2 NA|NA|NA S Uncharacterised protein family UPF0047 FFAGCILK_01335 1545702.LACWKB8_1629 3.6e-75 288.1 Lactobacillaceae tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1UZAR@1239,3F9SE@33958,4HBA2@91061,COG0149@1,COG0149@2 NA|NA|NA G Triose-phosphate isomerase FFAGCILK_01336 1545702.LACWKB8_1630 1.6e-96 359.4 Lactobacillaceae 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 Bacteria 1TRQY@1239,3FCBB@33958,4HC8E@91061,COG0191@1,COG0191@2 NA|NA|NA G Fructose-bisphosphate aldolase class-II FFAGCILK_01337 873448.STRPO_1585 9.1e-31 139.4 Bacilli 2.7.1.200 ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1 Bacteria 1VCNU@1239,4HM3X@91061,COG3414@1,COG3414@2 NA|NA|NA G Phosphotransferase system, galactitol-specific IIB component FFAGCILK_01338 1114972.AUAW01000022_gene1261 3.9e-158 564.7 Lactobacillaceae ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.5.1 Bacteria 1TQ10@1239,3F427@33958,4HA1Q@91061,COG3775@1,COG3775@2 NA|NA|NA G PTS system sugar-specific permease component FFAGCILK_01339 575594.ACOH01000005_gene1202 2.5e-27 128.6 Lactobacillaceae 2.7.1.200,2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02773 ko00051,ko00052,ko01100,ko01120,ko02060,map00051,map00052,map01100,map01120,map02060 M00273,M00279 R03232,R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.5.1 Bacteria 1VAHC@1239,3FCBX@33958,4HMTB@91061,COG1762@1,COG1762@2 NA|NA|NA GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 FFAGCILK_01341 1545702.LACWKB8_1633 1.5e-81 310.5 Lactobacillaceae manR ko:K02538 ko00000,ko03000 Bacteria 1TSGM@1239,3F482@33958,4HB3W@91061,COG3711@1,COG3711@2 NA|NA|NA K PRD domain FFAGCILK_01342 543734.LCABL_28900 1.2e-200 705.7 Lactobacillaceae Bacteria 1V0QQ@1239,3FAS6@33958,4I373@91061,COG0457@1,COG0457@2,COG1434@1,COG1434@2 NA|NA|NA S DUF218 domain FFAGCILK_01343 35841.BT1A1_2898 2.5e-122 445.3 Bacillus pdxA 1.1.1.262,1.1.1.408,1.1.1.409 ko:K00097,ko:K22024 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQGT@1239,1ZCWV@1386,4HA7N@91061,COG1995@1,COG1995@2 NA|NA|NA H Belongs to the PdxA family FFAGCILK_01344 35841.BT1A1_2899 3.3e-87 328.9 Bacillus 2.7.1.219,2.7.1.220 ko:K22129 ko00000,ko01000 Bacteria 1TPNP@1239,1ZD9B@1386,4HAGQ@91061,COG3395@1,COG3395@2 NA|NA|NA S Putative nucleotide-binding of sugar-metabolising enzyme FFAGCILK_01345 35841.BT1A1_2900 3.7e-105 388.3 Bacillus kdgT4 ko:K02526 ko00000,ko02000 2.A.10.1 Bacteria 1UPH1@1239,1ZDHF@1386,28H7K@1,2Z7JT@2,4HE88@91061 NA|NA|NA P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system FFAGCILK_01346 35841.BT1A1_2901 3.9e-78 299.3 Bacillus ko:K02667 ko02020,map02020 M00501 ko00000,ko00001,ko00002,ko02022,ko02035 Bacteria 1VSKG@1239,1ZS4S@1386,4ISBH@91061,COG2204@1,COG2204@2 NA|NA|NA K Propionate catabolism activator FFAGCILK_01347 1423775.BAMN01000013_gene765 1.5e-64 252.7 Lactobacillaceae kdsD 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 iAF987.Gmet_1278 Bacteria 1TQ04@1239,3F7HT@33958,4HGZ0@91061,COG0794@1,COG0794@2 NA|NA|NA M SIS domain FFAGCILK_01348 1423775.BAMN01000013_gene764 9.4e-48 196.4 Bacilli 2.7.1.194,2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02821 ko00051,ko00053,ko01100,ko01120,ko02060,map00051,map00053,map01100,map01120,map02060 M00273,M00283,M00550 R03232,R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.7.1 Bacteria 1V42N@1239,4HP6Y@91061,COG1762@1,COG1762@2 NA|NA|NA G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 FFAGCILK_01349 1423775.BAMN01000013_gene763 1.2e-32 145.6 Lactobacillaceae 2.7.1.194 ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 Bacteria 1VFJK@1239,3F8MG@33958,4HQ69@91061,COG3414@1,COG3414@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit FFAGCILK_01350 1423775.BAMN01000013_gene762 5e-200 703.7 Lactobacillaceae ulaA 2.7.1.194 ko:K02822,ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 Bacteria 1TQK5@1239,3F4Y4@33958,4HBAD@91061,COG3037@1,COG3037@2 NA|NA|NA S PTS system sugar-specific permease component FFAGCILK_01351 1423775.BAMN01000013_gene761 4.4e-97 361.3 Lactobacillaceae 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCK@1239,3FBJP@33958,4IQWR@91061,COG0329@1,COG0329@2 NA|NA|NA E Dihydrodipicolinate synthetase family FFAGCILK_01352 1423775.BAMN01000013_gene760 7.6e-80 303.5 Lactobacillaceae eda 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 Bacteria 1TS0F@1239,3F6AY@33958,4HG4G@91061,COG0800@1,COG0800@2 NA|NA|NA G KDPG and KHG aldolase FFAGCILK_01353 1423775.BAMN01000013_gene759 6.3e-208 730.7 Lactobacillaceae 2.7.1.194,2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02821 ko00051,ko00053,ko01100,ko01120,ko02060,map00051,map00053,map01100,map01120,map02060 M00273,M00283,M00550 R03232,R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.7.1 Bacteria 1TQT1@1239,3F5NN@33958,4H9N4@91061,COG1762@1,COG1762@2,COG3711@1,COG3711@2 NA|NA|NA G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 FFAGCILK_01354 543734.LCABL_28910 3.7e-137 494.2 Lactobacillaceae 4.1.2.14 ko:K17463 ko00030,ko01100,ko01120,map00030,map01100,map01120 M00061,M00631 R05605 RC00307,RC00435 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQX7@1239,2DBAP@1,2Z844@2,3F5QS@33958,4HABQ@91061 NA|NA|NA S KDGP aldolase FFAGCILK_01355 543734.LCABL_28920 1.2e-205 722.2 Lactobacillaceae selA 2.9.1.1 ko:K01042 ko00450,ko00970,map00450,map00970 R08219 RC01246 ko00000,ko00001,ko01000 Bacteria 1TQT8@1239,3F4MN@33958,4HC3U@91061,COG1921@1,COG1921@2 NA|NA|NA H L-seryl-tRNA selenium transferase FFAGCILK_01356 543734.LCABL_28930 3.8e-215 753.8 Lactobacillaceae dho 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPXM@1239,3F4S7@33958,4HBNV@91061,COG3964@1,COG3964@2 NA|NA|NA S Amidohydrolase family FFAGCILK_01357 543734.LCABL_28940 1.1e-119 436.0 Lactobacillaceae Bacteria 1TRJJ@1239,2CHGF@1,2Z7QV@2,3F5QZ@33958,4HC0E@91061 NA|NA|NA S Domain of unknown function (DUF4310) FFAGCILK_01358 543734.LCABL_28950 1.4e-136 492.3 Lactobacillaceae Bacteria 1TQ2N@1239,28HBR@1,2Z7NQ@2,3F5N2@33958,4HAZ6@91061 NA|NA|NA S Domain of unknown function (DUF4311) FFAGCILK_01359 543734.LCABL_28960 8.1e-58 229.6 Lactobacillaceae Bacteria 1VQQN@1239,2AJY2@1,31AM7@2,3F93K@33958,4IRVB@91061 NA|NA|NA S Domain of unknown function (DUF4312) FFAGCILK_01360 543734.LCABL_28970 6.9e-62 243.0 Lactobacillaceae Bacteria 1V7VZ@1239,292C3@1,2ZPWH@2,3F6XI@33958,4HIX7@91061 NA|NA|NA S Glycine-rich SFCGS FFAGCILK_01361 543734.LCABL_28980 9.6e-56 222.6 Lactobacillaceae Bacteria 1VI2Z@1239,2CG0N@1,32S2X@2,3F8H0@33958,4HQX6@91061 NA|NA|NA S PRD domain FFAGCILK_01362 543734.LCABL_28990 0.0 1183.7 Lactobacillaceae Bacteria 1U0UU@1239,3F5NV@33958,4HJZ1@91061,COG3711@1,COG3711@2 NA|NA|NA K Mga helix-turn-helix domain FFAGCILK_01363 543734.LCABL_29000 5.3e-124 450.3 Lactobacillaceae tal 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 Bacteria 1V4IX@1239,3FCEA@33958,4HJYI@91061,COG0176@1,COG0176@2 NA|NA|NA H Pfam:Transaldolase FFAGCILK_01364 543734.LCABL_29010 1.3e-63 248.8 Lactobacillaceae srlB GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0051179,GO:0051234,GO:0071702 2.7.1.198 ko:K02781 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 iB21_1397.B21_02519,iEC55989_1330.EC55989_2966,iECBD_1354.ECBD_1021,iECB_1328.ECB_02554,iECD_1391.ECD_02554,iECIAI39_1322.ECIAI39_2890,iECO111_1330.ECO111_3422,iECO26_1355.ECO26_3767,iECSE_1348.ECSE_2952,iECSP_1301.ECSP_3652,iECW_1372.ECW_m2903,iECs_1301.ECs3560,iEKO11_1354.EKO11_1071,iEcE24377_1341.EcE24377A_2988,iEcHS_1320.EcHS_A2840,iEcolC_1368.EcolC_1008,iG2583_1286.G2583_3352,iSSON_1240.SSON_2848,iWFL_1372.ECW_m2903,iZ_1308.Z4011 Bacteria 1VG8V@1239,3F7KY@33958,4HPTF@91061,COG3731@1,COG3731@2 NA|NA|NA G PTS system glucitol/sorbitol-specific IIA component FFAGCILK_01365 543734.LCABL_29020 9.6e-203 712.6 Lactobacillaceae srlE GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0090563 2.7.1.198 ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 Bacteria 1TQ8F@1239,3F5AP@33958,4HA7E@91061,COG3732@1,COG3732@2 NA|NA|NA G Sorbitol phosphotransferase enzyme II N-terminus FFAGCILK_01366 543734.LCABL_29030 6.3e-102 376.7 Lactobacillaceae srlA GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702 ko:K02783 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.4.1 iSBO_1134.SBO_2816 Bacteria 1URER@1239,3F445@33958,4HEHX@91061,COG3730@1,COG3730@2 NA|NA|NA G PTS system enzyme II sorbitol-specific factor FFAGCILK_01367 543734.LCABL_29040 9.4e-89 332.8 Lactobacillaceae gutM GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K02466 ko00000 Bacteria 1VHYU@1239,3F7F5@33958,4HP9S@91061,COG4578@1,COG4578@2 NA|NA|NA K Glucitol operon activator protein (GutM) FFAGCILK_01368 543734.LCABL_29050 0.0 1214.5 Lactobacillaceae srlM 2.7.1.194,2.7.1.200,2.7.1.202,2.7.1.204 ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 M00273,M00279,M00283,M00306,M00550,M00807 R03232,R05570,R07671,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1,4.A.5,4.A.5.1,4.A.7.1 Bacteria 1UZ36@1239,3F5E0@33958,4HDUK@91061,COG1762@1,COG1762@2,COG3711@1,COG3711@2 NA|NA|NA GKT Mga helix-turn-helix domain FFAGCILK_01369 543734.LCABL_29060 5e-145 520.4 Lactobacillaceae Bacteria 1TP2V@1239,3F4CR@33958,4HCAG@91061,COG1028@1,COG1028@2 NA|NA|NA IQ NAD dependent epimerase/dehydratase family FFAGCILK_01370 1140002.I570_00747 6.1e-34 150.6 Enterococcaceae ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1 Bacteria 1VAEB@1239,4B3AS@81852,4I277@91061,COG2190@1,COG2190@2 NA|NA|NA G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 FFAGCILK_01371 469596.HMPREF9488_01999 3.8e-212 744.6 Erysipelotrichia Bacteria 1TPM6@1239,3VPPH@526524,COG0446@1,COG0446@2,COG1902@1,COG1902@2 NA|NA|NA C Psort location Cytoplasmic, score 8.87 FFAGCILK_01372 1274374.CBLK010000079_gene4024 2.6e-189 668.3 Paenibacillaceae 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,26QRQ@186822,4HA1W@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family FFAGCILK_01373 1274374.CBLK010000079_gene4025 2.1e-87 329.3 Paenibacillaceae rbsR ko:K02529,ko:K17074 ko02010,map02010 M00589 ko00000,ko00001,ko00002,ko02000,ko03000 3.A.1.3.20 Bacteria 1TPH2@1239,26SN8@186822,4HBMD@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator FFAGCILK_01374 1034347.CAHJ01000066_gene2915 1.6e-130 473.0 Bacillus ptsG ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 Bacteria 1TP5X@1239,1ZC3X@1386,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2 NA|NA|NA G phosphotransferase system FFAGCILK_01375 543734.LCABL_29070 2.7e-137 494.6 Lactobacillaceae araD 4.1.2.17,5.1.3.4 ko:K01628,ko:K03077 ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120 M00550 R02262,R05850 RC00603,RC00604,RC01479 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS00590 Bacteria 1TPDV@1239,3F43P@33958,4H9W0@91061,COG0235@1,COG0235@2 NA|NA|NA G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source FFAGCILK_01376 543734.LCABL_29080 9e-150 536.2 Lactobacillaceae XK27_02985 Bacteria 1TR2E@1239,3F4G9@33958,4HCEA@91061,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase FFAGCILK_01377 543734.LCABL_29090 6.6e-167 593.2 Lactobacillaceae ulaE GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019324,GO:0019752,GO:0019852,GO:0034015,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0051186,GO:0071704 5.1.3.22 ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 M00550 R03244 RC00540 ko00000,ko00001,ko00002,ko01000 iEC55989_1330.EC55989_4754,iECSE_1348.ECSE_4495,iEcHS_1320.EcHS_A4441,iEcSMS35_1347.EcSMS35_4668,iYL1228.KPN_04590 Bacteria 1TSMS@1239,3F5GZ@33958,4HBBU@91061,COG3623@1,COG3623@2 NA|NA|NA G Xylose isomerase-like TIM barrel FFAGCILK_01378 543734.LCABL_29100 5.7e-138 496.9 Lactobacillaceae repA ko:K02444,ko:K03436 ko00000,ko03000 Bacteria 1UYQX@1239,3F6Z8@33958,4HMB5@91061,COG1349@1,COG1349@2 NA|NA|NA K DeoR C terminal sensor domain FFAGCILK_01379 543734.LCABL_29110 9.6e-115 419.5 Lactobacillaceae ulaD GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009056,GO:0009109,GO:0009111,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0019852,GO:0019854,GO:0033982,GO:0042365,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046872,GO:0051186,GO:0051187,GO:0071704,GO:1901575 4.1.1.85,4.1.2.43 ko:K03078,ko:K08093 ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230 M00345,M00550,M00580 R05338,R07125 RC00421,RC00422,RC01721 ko00000,ko00001,ko00002,ko01000 iAF1260.b4196,iAPECO1_1312.APECO1_2196,iBWG_1329.BWG_3908,iE2348C_1286.E2348C_4519,iECDH10B_1368.ECDH10B_4391,iECDH1ME8569_1439.ECDH1ME8569_4053,iECED1_1282.ECED1_4983,iECIAI1_1343.ECIAI1_4429,iECNA114_1301.ECNA114_4412,iECOK1_1307.ECOK1_4710,iECP_1309.ECP_4441,iECS88_1305.ECS88_4782,iECSE_1348.ECSE_4494,iECSF_1327.ECSF_4082,iEcDH1_1363.EcDH1_3797,iJO1366.b4196,iJR904.b4196,iLF82_1304.LF82_2375,iNRG857_1313.NRG857_21325,iUMN146_1321.UM146_21220,iY75_1357.Y75_RS21850 Bacteria 1TSHP@1239,3F3YT@33958,4HCA8@91061,COG0269@1,COG0269@2 NA|NA|NA G Orotidine 5'-phosphate decarboxylase / HUMPS family FFAGCILK_01380 543734.LCABL_29120 9.7e-46 189.1 Lactobacillaceae sgaB 2.7.1.194,2.7.1.200,2.7.1.204 ko:K02774,ko:K02822,ko:K20113 ko00052,ko00053,ko01100,ko01120,ko02060,map00052,map00053,map01100,map01120,map02060 M00279,M00283,M00550,M00807 R05570,R07671,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5,4.A.5.1,4.A.7.1 Bacteria 1VHNP@1239,3F78S@33958,4IR7Z@91061,COG3414@1,COG3414@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit FFAGCILK_01381 543734.LCABL_29130 3.5e-280 970.3 Lactobacillaceae ulaA ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.7.1 Bacteria 1TQK5@1239,3FC40@33958,4HB7T@91061,COG3037@1,COG3037@2 NA|NA|NA S PTS system sugar-specific permease component FFAGCILK_01382 543734.LCABL_29140 5e-81 307.0 Lactobacillaceae cmtB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0015711,GO:0015749,GO:0015849,GO:0015882,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0034220,GO:0035461,GO:0044464,GO:0046942,GO:0051179,GO:0051180,GO:0051181,GO:0051182,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090585,GO:0098656,GO:1903825,GO:1905039 2.7.1.194,2.7.1.197,2.7.1.200,2.7.1.202,2.7.1.204 ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02798,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 M00273,M00274,M00279,M00283,M00306,M00550,M00807 R02704,R03232,R05570,R07671,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1,4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5,4.A.5,4.A.5.1,4.A.7.1 iAF1260.b4195,iBWG_1329.BWG_3907,iECABU_c1320.ECABU_c47530,iECDH10B_1368.ECDH10B_4390,iECDH1ME8569_1439.ECDH1ME8569_4052,iECH74115_1262.ECH74115_5711,iECSP_1301.ECSP_5295,iECUMN_1333.ECUMN_4728,iECs_1301.ECs5171,iEcDH1_1363.EcDH1_3798,iEcSMS35_1347.EcSMS35_4666,iG2583_1286.G2583_5022,iJO1366.b4195,iSbBS512_1146.SbBS512_E4725,iY75_1357.Y75_RS21845,iZ_1308.Z5804,ic_1306.c5284 Bacteria 1V892@1239,3F6HA@33958,4IQ69@91061,COG1762@1,COG1762@2 NA|NA|NA G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 FFAGCILK_01383 543734.LCABL_29150 1.9e-216 758.1 Lactobacillaceae ulaG GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009056,GO:0009109,GO:0009111,GO:0009987,GO:0016052,GO:0016054,GO:0016787,GO:0016788,GO:0019752,GO:0019852,GO:0019854,GO:0030145,GO:0035460,GO:0042365,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046872,GO:0046914,GO:0051186,GO:0051187,GO:0052689,GO:0071704,GO:1901575 ko:K03476 ko00053,ko01100,ko01120,map00053,map01100,map01120 M00550 R07677 RC02793 ko00000,ko00001,ko00002,ko01000 iAF1260.b4192,iAPECO1_1312.APECO1_2200,iBWG_1329.BWG_3904,iEC55989_1330.EC55989_4749,iECDH10B_1368.ECDH10B_4387,iECH74115_1262.ECH74115_5708,iECIAI1_1343.ECIAI1_4425,iECIAI39_1322.ECIAI39_4657,iECO111_1330.ECO111_5022,iECO26_1355.ECO26_5358,iECSE_1348.ECSE_4490,iECSP_1301.ECSP_5292,iECUMN_1333.ECUMN_4725,iECW_1372.ECW_m4554,iEKO11_1354.EKO11_4120,iEcE24377_1341.EcE24377A_4752,iEcHS_1320.EcHS_A4436,iEcolC_1368.EcolC_3821,iJO1366.b4192,iUTI89_1310.UTI89_C4792,iWFL_1372.ECW_m4554,iY75_1357.Y75_RS21830,iYL1228.KPN_04585,ic_1306.c5280 Bacteria 1TSFV@1239,3F58F@33958,4HBNW@91061,COG2220@1,COG2220@2 NA|NA|NA S Beta-lactamase superfamily domain FFAGCILK_01384 543734.LCABL_29160 3.4e-126 457.6 Lactobacillaceae rpiA GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,5.3.1.6 ko:K00851,ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056,R01737 RC00002,RC00017,RC00434 ko00000,ko00001,ko00002,ko01000 Bacteria 1V1DB@1239,3F43N@33958,4HFQ7@91061,COG0120@1,COG0120@2 NA|NA|NA G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate FFAGCILK_01385 543734.LCABL_29170 8.2e-196 689.5 Lactobacillaceae Bacteria 1TPWP@1239,3F3WG@33958,4HABC@91061,COG1063@1,COG1063@2 NA|NA|NA C Zinc-binding dehydrogenase FFAGCILK_01386 543734.LCABL_29180 2.6e-91 342.0 Lactobacillaceae 4.1.2.13 ko:K11645 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR4S@1239,3F9XH@33958,4HWA1@91061,COG1830@1,COG1830@2 NA|NA|NA G DeoC/LacD family aldolase FFAGCILK_01387 543734.LCABL_29200 7.8e-120 436.4 Lactobacillaceae rpe 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQK8@1239,3F4KX@33958,4H9RW@91061,COG0036@1,COG0036@2 NA|NA|NA G Belongs to the ribulose-phosphate 3-epimerase family FFAGCILK_01388 543734.LCABL_29210 1.1e-158 565.8 Lactobacillaceae ko:K02747,ko:K02796,ko:K02815,ko:K17467 ko00030,ko00051,ko00052,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00052,map00520,map01100,map01120,map02060 M00276,M00277,M00278,M00610 R02630,R04076,R08366,R10407 RC00017,RC01069,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.17,4.A.6.1.3,4.A.6.1.4 Bacteria 1TRWR@1239,3FBHR@33958,4HUGC@91061,COG3716@1,COG3716@2 NA|NA|NA G PTS system mannose/fructose/sorbose family IID component FFAGCILK_01389 543734.LCABL_29220 1.7e-126 458.8 Lactobacillaceae ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 Bacteria 1TSZ2@1239,3F8K4@33958,4HTCA@91061,COG3715@1,COG3715@2 NA|NA|NA G PTS system sorbose-specific iic component FFAGCILK_01390 543734.LCABL_29230 3.6e-82 310.8 Lactobacillaceae 2.7.1.191 ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 Bacteria 1V8X5@1239,3FBAW@33958,4HW54@91061,COG3444@1,COG3444@2 NA|NA|NA G PTS system sorbose subfamily IIB component FFAGCILK_01391 543734.LCABL_29240 1e-72 279.3 Lactobacillaceae 2.7.1.191 ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 Bacteria 1UXMQ@1239,3FA7C@33958,4IHS7@91061,COG2893@1,COG2893@2 NA|NA|NA G PTS system fructose IIA component FFAGCILK_01392 543734.LCABL_29250 1.7e-204 718.4 Lactobacillaceae gutB 1.1.1.303,1.1.1.4,1.1.1.405 ko:K00004,ko:K05352 ko00040,ko00650,ko01100,map00040,map00650,map01100 R01525,R02855,R02946,R10504 RC00089,RC00205,RC00525 ko00000,ko00001,ko01000 Bacteria 1TQSR@1239,3F4VQ@33958,4HCCH@91061,COG1063@1,COG1063@2 NA|NA|NA E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate FFAGCILK_01393 543734.LCABL_29260 6.4e-134 483.4 Lactobacillaceae ko:K02444 ko00000,ko03000 Bacteria 1V813@1239,3FBHY@33958,4HK5K@91061,COG1349@1,COG1349@2 NA|NA|NA K DeoR C terminal sensor domain FFAGCILK_01394 543734.LCABL_29270 0.0 1639.8 Lactobacillaceae xfp 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 Bacteria 1TR23@1239,3F3TZ@33958,4HC2J@91061,COG3957@1,COG3957@2 NA|NA|NA G Phosphoketolase FFAGCILK_01395 543734.LCABL_29280 1.4e-159 568.9 Lactobacillaceae bglK_1 Bacteria 1TRQ7@1239,3F3ZI@33958,4HE30@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family FFAGCILK_01396 543734.LCABL_29290 1.2e-182 645.6 Lactobacillaceae aspG GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 ko:K01424,ko:K01444,ko:K13051 ko00250,ko00460,ko00511,ko01100,ko01110,ko04142,map00250,map00460,map00511,map01100,map01110,map04142 R00485 RC00010,RC02798 ko00000,ko00001,ko01000,ko01002 Bacteria 1TSWB@1239,3F3SI@33958,4HED0@91061,COG1446@1,COG1446@2 NA|NA|NA E Asparaginase FFAGCILK_01397 543734.LCABL_29300 4.2e-253 880.2 Lactobacillaceae 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPEG@1239,3F5AY@33958,4HBQA@91061,COG0624@1,COG0624@2 NA|NA|NA E Peptidase family M20/M25/M40 FFAGCILK_01398 543734.LCABL_29310 1.1e-130 472.6 Lactobacillaceae ymfC ko:K03710 ko00000,ko03000 Bacteria 1V338@1239,3F682@33958,4HGUM@91061,COG2188@1,COG2188@2 NA|NA|NA K UTRA FFAGCILK_01399 543734.LCABL_29320 7.2e-305 1052.4 Bacilli aspD 4.1.1.12 ko:K09758 ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230 R00397,R00863 RC00282,RC00399,RC00400 ko00000,ko00001,ko01000 Bacteria 1TQP8@1239,4HECY@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase FFAGCILK_01400 543734.LCABL_29330 5.8e-214 750.0 Lactobacillaceae uhpT Bacteria 1TQZ7@1239,3F54C@33958,4HERG@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily FFAGCILK_01401 543734.LCABL_29340 2e-207 728.0 Lactobacillaceae 3.2.1.51 ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 GH29 Bacteria 1TQH2@1239,3F4ZS@33958,4HTW2@91061,COG3669@1,COG3669@2 NA|NA|NA G Alpha-L-fucosidase FFAGCILK_01402 543734.LCABL_29350 3.3e-71 274.6 Lactobacillaceae Bacteria 1U7UB@1239,2BMK9@1,30BB1@2,3FA6T@33958,4HYFJ@91061 NA|NA|NA S Domain of unknown function (DUF4428) FFAGCILK_01403 543734.LCABL_29360 5.6e-283 979.5 Lactobacillaceae xylB 2.7.1.12,2.7.1.17 ko:K00851,ko:K00854 ko00030,ko00040,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map01100,map01110,map01120,map01130,map01200 M00014 R01639,R01737 RC00002,RC00017,RC00538 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ1I@1239,3F4R2@33958,4H9W6@91061,COG1070@1,COG1070@2 NA|NA|NA G Belongs to the FGGY kinase family FFAGCILK_01404 543734.LCABL_29370 1.4e-203 715.3 Lactobacillaceae Bacteria 1TPWP@1239,3F3WG@33958,4HABC@91061,COG1063@1,COG1063@2 NA|NA|NA C Zinc-binding dehydrogenase FFAGCILK_01405 543734.LCABL_29380 3.3e-155 554.3 Lactobacillaceae ko:K02747,ko:K02796,ko:K02815,ko:K17467 ko00030,ko00051,ko00052,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00052,map00520,map01100,map01120,map02060 M00276,M00277,M00278,M00610 R02630,R04076,R08366,R10407 RC00017,RC01069,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.17,4.A.6.1.3,4.A.6.1.4 Bacteria 1TT8N@1239,3F9BA@33958,4HUFH@91061,COG3716@1,COG3716@2 NA|NA|NA G PTS system mannose/fructose/sorbose family IID component FFAGCILK_01406 543734.LCABL_29390 1.8e-136 491.9 Lactobacillaceae ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 Bacteria 1TSZ2@1239,3FC41@33958,4HUI1@91061,COG3715@1,COG3715@2 NA|NA|NA G PTS system sorbose-specific iic component FFAGCILK_01407 543734.LCABL_29400 1.6e-82 312.0 Lactobacillaceae 2.7.1.191 ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 Bacteria 1V41G@1239,3F9CU@33958,4HVY1@91061,COG3444@1,COG3444@2 NA|NA|NA G PTS system sorbose subfamily IIB component FFAGCILK_01408 543734.LCABL_29410 5.5e-71 273.5 Lactobacillaceae ahaA 2.7.1.191 ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 Bacteria 1VBP2@1239,3F89V@33958,4HW58@91061,COG2893@1,COG2893@2 NA|NA|NA G PTS system fructose IIA component FFAGCILK_01409 543734.LCABL_29420 1.9e-267 928.3 Lactobacillaceae licR 2.7.1.194,2.7.1.200,2.7.1.202,2.7.1.204 ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 M00273,M00279,M00283,M00306,M00550,M00807 R03232,R05570,R07671,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1,4.A.5,4.A.5.1,4.A.7.1 Bacteria 1TQ6D@1239,3FA43@33958,4HV5N@91061,COG1762@1,COG1762@2,COG3711@1,COG3711@2 NA|NA|NA K Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 FFAGCILK_01410 543734.LCABL_29450 8.5e-159 566.2 Lactobacillaceae Bacteria 1UXZF@1239,3F99T@33958,4HTVJ@91061,COG0191@1,COG0191@2 NA|NA|NA G Fructose-bisphosphate aldolase class-II FFAGCILK_01411 543734.LCABL_29460 4.9e-271 939.9 Lactobacillaceae rhaB 2.7.1.12,2.7.1.17,2.7.1.5 ko:K00848,ko:K00851,ko:K00854 ko00030,ko00040,ko00051,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map00051,map01100,map01110,map01120,map01130,map01200 M00014 R01639,R01737,R01902,R03014 RC00002,RC00017,RC00538 ko00000,ko00001,ko00002,ko01000 Bacteria 1VS9N@1239,3F99X@33958,4HU27@91061,COG1070@1,COG1070@2 NA|NA|NA G FGGY family of carbohydrate kinases, C-terminal domain FFAGCILK_01412 543734.LCABL_29470 8.3e-257 892.5 Lactobacillaceae gatC ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.5.1 Bacteria 1TQ10@1239,3F427@33958,4HA1Q@91061,COG3775@1,COG3775@2 NA|NA|NA G PTS system sugar-specific permease component FFAGCILK_01413 543734.LCABL_29480 1.1e-47 195.7 Lactobacillaceae 2.7.1.194,2.7.1.200,2.7.1.204 ko:K02774,ko:K02822,ko:K20113 ko00052,ko00053,ko01100,ko01120,ko02060,map00052,map00053,map01100,map01120,map02060 M00279,M00283,M00550,M00807 R05570,R07671,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5,4.A.5.1,4.A.7.1 Bacteria 1VIQT@1239,3F7ZQ@33958,4HYM1@91061,COG3414@1,COG3414@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit FFAGCILK_01414 543734.LCABL_29490 8.4e-79 299.7 Lactobacillaceae 2.7.1.194,2.7.1.200,2.7.1.202,2.7.1.204 ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 M00273,M00279,M00283,M00306,M00550,M00807 R03232,R05570,R07671,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1,4.A.5,4.A.5.1,4.A.7.1 Bacteria 1VAHC@1239,3F9SN@33958,4HJ5R@91061,COG1762@1,COG1762@2 NA|NA|NA GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 FFAGCILK_01415 543734.LCABL_29500 6.9e-161 573.2 Lactobacillaceae gatY iECNA114_1301.ECNA114_3597,iECSF_1327.ECSF_3307 Bacteria 1TQ01@1239,3F9GB@33958,4HT8R@91061,COG0191@1,COG0191@2 NA|NA|NA G Fructose-bisphosphate aldolase class-II FFAGCILK_01416 543734.LCABL_29510 6.3e-134 483.4 Lactobacillaceae farR ko:K03710 ko00000,ko03000 Bacteria 1V724@1239,3F9M5@33958,4HVH9@91061,COG2188@1,COG2188@2 NA|NA|NA K Helix-turn-helix domain FFAGCILK_01417 543734.LCABL_29520 4.1e-89 334.0 Bacilli hisA 5.3.1.16 ko:K01814,ko:K03828 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 Bacteria 1UIWB@1239,4ISUG@91061,COG1247@1,COG1247@2 NA|NA|NA M Acetyltransferase (GNAT) domain FFAGCILK_01418 543734.LCABL_29530 1.9e-101 375.2 Lactobacillaceae laaE Bacteria 1VEN3@1239,3F6IE@33958,4HS7A@91061,COG1695@1,COG1695@2 NA|NA|NA K Transcriptional regulator PadR-like family FFAGCILK_01419 543734.LCABL_29540 3.6e-288 996.9 Lactobacillaceae chaT1 ko:K03446 M00701 ko00000,ko00002,ko02000 2.A.1.3 Bacteria 1VRVX@1239,3F4T2@33958,4HV95@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily FFAGCILK_01420 543734.LCABL_29550 9.6e-86 322.8 Lactobacillaceae GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464 Bacteria 1UHNV@1239,3F7IJ@33958,4IS4R@91061,COG0454@1,COG0454@2 NA|NA|NA K Acetyltransferase (GNAT) domain FFAGCILK_01421 543734.LCABL_29560 5.3e-92 343.6 Lactobacillaceae yveA 3.5.1.19 ko:K08281 ko00760,ko01100,map00760,map01100 R01268 RC00100 ko00000,ko00001,ko01000 Bacteria 1VF7P@1239,3FC9Z@33958,4HQSB@91061,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family FFAGCILK_01422 568703.LGG_02642 2.6e-36 157.9 Lactobacillaceae Bacteria 1VFF0@1239,2E9Y3@1,3343R@2,3F8BC@33958,4HPUY@91061 NA|NA|NA FFAGCILK_01423 543734.LCABL_29570 9.3e-56 222.6 Lactobacillaceae Bacteria 1VFF0@1239,2E9Y3@1,3343R@2,3F8BC@33958,4HPUY@91061 NA|NA|NA FFAGCILK_01425 543734.LCABL_29590 2.4e-93 348.2 Lactobacillaceae Bacteria 1VDCA@1239,3F7ZF@33958,4HN0T@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix domain FFAGCILK_01426 568703.LGG_02766 9.8e-121 439.5 Lactobacillaceae glpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1V3W4@1239,3F4E3@33958,4HFNQ@91061,COG0584@1,COG0584@2 NA|NA|NA C glycerophosphoryl diester phosphodiesterase FFAGCILK_01427 543734.LCABL_29620 2.1e-70 271.6 Lactobacillaceae arsC GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 ko:K03741 ko00000,ko01000 Bacteria 1V3JW@1239,3F6GQ@33958,4HH49@91061,COG0394@1,COG0394@2 NA|NA|NA T Belongs to the low molecular weight phosphotyrosine protein phosphatase family FFAGCILK_01428 543734.LCABL_29630 8.6e-254 882.5 Lactobacillaceae ugpB ko:K05813 ko02010,map02010 M00198 ko00000,ko00001,ko00002,ko02000 3.A.1.1.3 Bacteria 1TS64@1239,3FC76@33958,4HARC@91061,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein FFAGCILK_01429 543734.LCABL_29640 3.4e-149 534.3 Lactobacillaceae ugpE ko:K02026,ko:K05815 ko02010,map02010 M00198,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3 Bacteria 1TR0I@1239,3F4Q5@33958,4HB8C@91061,COG0395@1,COG0395@2 NA|NA|NA G ABC transporter permease FFAGCILK_01430 543734.LCABL_29650 2.5e-164 584.7 Lactobacillaceae ugpA ko:K02025,ko:K05814,ko:K15771 ko02010,map02010 M00198,M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.3 Bacteria 1TREE@1239,3F464@33958,4HCD0@91061,COG1175@1,COG1175@2 NA|NA|NA P ABC-type sugar transport systems, permease components FFAGCILK_01431 543734.LCABL_29660 1.5e-211 741.9 Lactobacillaceae ugpC 3.6.3.20 ko:K05816,ko:K10111,ko:K10112,ko:K17240 ko02010,map02010 M00194,M00196,M00197,M00198,M00200,M00201,M00204,M00206,M00207,M00491,M00599,M00602,M00605,M00606 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1,3.A.1.1.3,3.A.1.1.38 Bacteria 1TP2M@1239,3FC3B@33958,4HA50@91061,COG3842@1,COG3842@2 NA|NA|NA E Belongs to the ABC transporter superfamily FFAGCILK_01432 543734.LCABL_29670 2.4e-267 927.5 Lactobacillaceae pncB GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 R01724 RC00033 ko00000,ko00001,ko01000 Bacteria 1TPDW@1239,3F3K7@33958,4HAI4@91061,COG1488@1,COG1488@2 NA|NA|NA F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP FFAGCILK_01433 543734.LCABL_29680 9.9e-108 396.0 Lactobacillaceae pncA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0017144,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 ko:K16788 ko00000,ko02000 2.A.88.5 iSB619.SA_RS09955 Bacteria 1V1CY@1239,3F41F@33958,4HFRS@91061,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family FFAGCILK_01434 543734.LCABL_29690 9.5e-135 486.1 Lactobacillaceae 3.6.1.13,3.6.1.55 ko:K01515,ko:K03574 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000,ko03400 Bacteria 1UZ4E@1239,3FBCZ@33958,4IPMJ@91061,COG1051@1,COG1051@2,COG4111@1,COG4111@2 NA|NA|NA F NUDIX domain FFAGCILK_01435 543734.LCABL_29700 2.9e-145 521.2 Firmicutes 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1VAJP@1239,COG2367@1,COG2367@2 NA|NA|NA V Beta-lactamase enzyme family FFAGCILK_01436 543734.LCABL_29710 5.6e-192 676.8 Lactobacillaceae ykfB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 ko:K19802 R10938 RC03309 ko00000,ko01000 Bacteria 1TQMS@1239,3F4XQ@33958,4HCY5@91061,COG4948@1,COG4948@2 NA|NA|NA M Belongs to the mandelate racemase muconate lactonizing enzyme family FFAGCILK_01437 543734.LCABL_29720 1.5e-194 685.3 Lactobacillaceae blaA6 Bacteria 1U828@1239,3F4K3@33958,4HA0Q@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase FFAGCILK_01438 543734.LCABL_29730 7.8e-155 553.1 Lactobacillaceae murQ 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 R08555 RC00397,RC00746 ko00000,ko00001,ko01000 Bacteria 1TPSF@1239,3F4T1@33958,4HBWP@91061,COG2103@1,COG2103@2 NA|NA|NA G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate FFAGCILK_01439 543734.LCABL_29740 8.9e-162 576.2 Lactobacillaceae ybbH_2 Bacteria 1V26Y@1239,3FBJG@33958,4IQVW@91061,COG1737@1,COG1737@2 NA|NA|NA K Helix-turn-helix domain, rpiR family FFAGCILK_01440 543734.LCABL_29750 3.1e-81 307.8 Lactobacillaceae 2.7.1.191 ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 Bacteria 1V58C@1239,3F79W@33958,4HJ9Y@91061,COG3444@1,COG3444@2 NA|NA|NA G PTS system sorbose subfamily IIB component FFAGCILK_01441 543734.LCABL_29760 1.9e-150 538.5 Lactobacillaceae ko:K02747,ko:K02796,ko:K02815,ko:K17467 ko00030,ko00051,ko00052,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00052,map00520,map01100,map01120,map02060 M00276,M00277,M00278,M00610 R02630,R04076,R08366,R10407 RC00017,RC01069,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.17,4.A.6.1.3,4.A.6.1.4 Bacteria 1UZG2@1239,3F5FR@33958,4IQM5@91061,COG3716@1,COG3716@2 NA|NA|NA G PTS system mannose/fructose/sorbose family IID component FFAGCILK_01442 543734.LCABL_29770 6.8e-129 466.8 Lactobacillaceae ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 Bacteria 1UYP8@1239,3F5ZV@33958,4IQM3@91061,COG3715@1,COG3715@2 NA|NA|NA G PTS system sorbose-specific iic component FFAGCILK_01443 543734.LCABL_29780 7.7e-202 709.5 Lactobacillaceae Bacteria 1U5BI@1239,3F57I@33958,4HE49@91061,COG3568@1,COG3568@2 NA|NA|NA S endonuclease exonuclease phosphatase family protein FFAGCILK_01444 543734.LCABL_29790 1.2e-171 609.0 Lactobacillaceae nrnA GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPXX@1239,3F4FC@33958,4H9ZW@91061,COG0618@1,COG0618@2 NA|NA|NA S DHHA1 domain protein FFAGCILK_01445 568703.LGG_02785 1.1e-114 419.5 Lactobacillaceae Bacteria 1TSAZ@1239,3F4S0@33958,4HIIG@91061,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase FFAGCILK_01446 543734.LCABL_29820 3.4e-52 210.7 Lactobacillaceae sugE ko:K11741 ko00000,ko02000 2.A.7.1 Bacteria 1VEZX@1239,3F7D6@33958,4HKXB@91061,COG2076@1,COG2076@2 NA|NA|NA U Multidrug resistance protein FFAGCILK_01447 543734.LCABL_29870 1.1e-133 482.6 Lactobacillaceae ko:K06976 ko00000 Bacteria 1TRN7@1239,3F84U@33958,4HWMG@91061,COG3393@1,COG3393@2 NA|NA|NA S -acetyltransferase FFAGCILK_01448 543734.LCABL_29880 9.5e-94 349.4 Lactobacillaceae MA20_25245 Bacteria 1VEEJ@1239,3FBDP@33958,4HP6M@91061,COG0454@1,COG0456@2 NA|NA|NA K FR47-like protein FFAGCILK_01449 543734.LCABL_29890 1.3e-93 349.0 Bacilli hisB GO:0000105,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006082,GO:0006520,GO:0006547,GO:0006629,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008652,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0033692,GO:0034200,GO:0034637,GO:0034641,GO:0034645,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046401,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903509 2.7.7.71,3.1.3.15,3.1.3.82,3.1.3.83,4.2.1.19,5.3.1.28,6.3.2.10 ko:K01089,ko:K01929,ko:K02843,ko:K03271,ko:K03273,ko:K15669 ko00300,ko00340,ko00540,ko00550,ko01100,ko01110,ko01230,ko01502,map00300,map00340,map00540,map00550,map01100,map01110,map01230,map01502 M00026,M00064,M00080 R03013,R03457,R04573,R04617,R05645,R05647,R09768,R09769,R09771,R09772 RC00002,RC00017,RC00064,RC00141,RC00434,RC00932 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko01011 GT9 iB21_1397.B21_00198,iEC55989_1330.EC55989_0198,iECBD_1354.ECBD_3418,iECB_1328.ECB_00199,iECD_1391.ECD_00199,iECIAI1_1343.ECIAI1_0202,iECO103_1326.ECO103_0200,iECO111_1330.ECO111_2746,iECS88_1305.ECS88_2121,iECSE_1348.ECSE_0202,iETEC_1333.ETEC_0196,iEcHS_1320.EcHS_A0204,iEcolC_1368.EcolC_3459,iIT341.HP0860,iJN746.PP_0059,iUMNK88_1353.UMNK88_2570 Bacteria 1V6DW@1239,4HJ23@91061,COG0241@1,COG0241@2 NA|NA|NA E HAD-hyrolase-like FFAGCILK_01450 543734.LCABL_29900 2.2e-185 654.8 Lactobacillaceae GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0007275,GO:0007399,GO:0008150,GO:0009987,GO:0010975,GO:0016020,GO:0019867,GO:0022008,GO:0030154,GO:0031090,GO:0031344,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032501,GO:0032502,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045595,GO:0045664,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050773,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051239,GO:0051960,GO:0060284,GO:0065007,GO:0098588,GO:0098805,GO:0120035,GO:2000026 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 1TQ0M@1239,3F4EJ@33958,4HA8M@91061,COG0604@1,COG0604@2 NA|NA|NA C nadph quinone reductase FFAGCILK_01451 543734.LCABL_29910 3.9e-139 500.7 Lactobacillaceae wzb 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1V6Q5@1239,3F5X1@33958,4HJKY@91061,COG2365@1,COG2365@2 NA|NA|NA T Tyrosine phosphatase family FFAGCILK_01452 543734.LCABL_29930 3.1e-79 301.2 Lactobacillaceae Bacteria 1V8AJ@1239,3F6YY@33958,4HPGU@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain FFAGCILK_01453 1136177.KCA1_2468 1.2e-42 179.5 Bacilli Bacteria 1V3QI@1239,4IPUS@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance FFAGCILK_01454 1231336.L248_1998 1.4e-123 449.5 Lactobacillaceae 1.1.1.219 ko:K00091 ko00000,ko01000 Bacteria 1UEMD@1239,3F5S3@33958,4HDN7@91061,COG0451@1,COG0451@2 NA|NA|NA GM Male sterility protein FFAGCILK_01455 568703.LGG_02795 6.9e-44 183.7 Lactobacillaceae Bacteria 1VZP6@1239,2DYM8@1,34AAZ@2,3F99W@33958,4HZAB@91061 NA|NA|NA FFAGCILK_01456 543734.LCABL_29940 9.6e-77 292.7 Lactobacillaceae yiaC ko:K03826 ko00000,ko01000 Bacteria 1VAFS@1239,3F7FI@33958,4HIRW@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain FFAGCILK_01457 543734.LCABL_29950 1.3e-76 292.4 Lactobacillaceae 2.3.1.82 ko:K03830,ko:K18816 br01600,ko00000,ko01000,ko01504 Bacteria 1UHUT@1239,3FBXG@33958,4HSN0@91061,COG0454@1,COG0454@2 NA|NA|NA K Acetyltransferase (GNAT) domain FFAGCILK_01458 543734.LCABL_29990 8e-82 309.7 Lactobacillaceae rlmH 2.1.1.177 ko:K00783 ko00000,ko01000,ko03009 Bacteria 1V3JM@1239,3F3YX@33958,4HFP8@91061,COG1576@1,COG1576@2 NA|NA|NA J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA FFAGCILK_01459 543734.LCABL_30000 4.1e-198 697.2 Lactobacillaceae ybiR GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1TQCH@1239,3F4CJ@33958,4HEW7@91061,COG1055@1,COG1055@2 NA|NA|NA P Citrate transporter FFAGCILK_01460 568703.LGG_02799 3.2e-70 271.9 Lactobacillaceae Bacteria 1U7H9@1239,29Q2V@1,30B3P@2,3F9PB@33958,4IHDU@91061 NA|NA|NA FFAGCILK_01461 543734.LCABL_30020 2.8e-257 894.0 Lactobacillaceae Bacteria 1TP2D@1239,3F541@33958,4HB9G@91061,COG0624@1,COG0624@2 NA|NA|NA E Peptidase dimerisation domain FFAGCILK_01462 543734.LCABL_30030 5.4e-300 1036.2 Lactobacillaceae ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TNYQ@1239,3F3JE@33958,4HAMK@91061,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter, substratebinding protein FFAGCILK_01463 568703.LGG_02802 2.6e-102 379.0 Lactobacillaceae Bacteria 1U7DH@1239,29Q2V@1,30B1G@2,3F9FB@33958,4IH9F@91061 NA|NA|NA FFAGCILK_01464 543734.LCABL_30050 0.0 1120.5 Lactobacillaceae cadA Bacteria 1TQ07@1239,3F4JI@33958,4H9SP@91061,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase FFAGCILK_01465 543734.LCABL_30060 6e-76 290.0 Lactobacillaceae hsp3 ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 1VG0E@1239,3F7DR@33958,4HPDH@91061,COG0071@1,COG0071@2 NA|NA|NA O Belongs to the small heat shock protein (HSP20) family FFAGCILK_01466 543734.LCABL_30070 4.1e-71 273.9 Lactobacillaceae Bacteria 1VY7K@1239,2F916@1,341CT@2,3F70S@33958,4HX4B@91061 NA|NA|NA S Iron-sulphur cluster biosynthesis FFAGCILK_01467 543734.LCABL_30080 1e-211 742.7 Lactobacillaceae htrA GO:0008150,GO:0009266,GO:0009628,GO:0050896 3.4.21.107 ko:K04691,ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1TRM8@1239,3F45X@33958,4HA31@91061,COG0265@1,COG0265@2 NA|NA|NA O serine protease FFAGCILK_01468 543734.LCABL_30090 1.2e-154 552.4 Lactobacillaceae vicX 3.1.26.11 ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Bacteria 1TQ8E@1239,3F3S4@33958,4HAKD@91061,COG1235@1,COG1235@2 NA|NA|NA S domain protein FFAGCILK_01469 543734.LCABL_30100 1.3e-140 505.8 Lactobacillaceae yycI Bacteria 1V1FW@1239,3F3PV@33958,4HFWZ@91061,COG4853@1,COG4853@2 NA|NA|NA S YycH protein FFAGCILK_01470 543734.LCABL_30110 1.6e-255 888.3 Lactobacillaceae yycH Bacteria 1V32Y@1239,3F4HR@33958,4HG2Q@91061,COG4863@1,COG4863@2 NA|NA|NA S YycH protein FFAGCILK_01471 543734.LCABL_30120 0.0 1174.8 Lactobacillaceae vicK 2.7.13.3 ko:K07652 ko02020,map02020 M00459 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TQ1H@1239,3F45G@33958,4HA52@91061,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase FFAGCILK_01472 543734.LCABL_30130 8.1e-131 473.0 Lactobacillaceae Bacteria 1TPQG@1239,3F4FB@33958,4HA8Q@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator FFAGCILK_01473 543734.LCABL_30140 2.2e-70 271.6 Lactobacillaceae 3.1.1.24 ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991 RC00825 ko00000,ko00001,ko00002,ko01000 Bacteria 1V02M@1239,3FBGC@33958,4HN2K@91061,COG0596@1,COG0596@2 NA|NA|NA S Alpha/beta hydrolase family FFAGCILK_01474 543734.LCABL_30140 4.7e-38 163.3 Lactobacillaceae 3.1.1.24 ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991 RC00825 ko00000,ko00001,ko00002,ko01000 Bacteria 1V02M@1239,3FBGC@33958,4HN2K@91061,COG0596@1,COG0596@2 NA|NA|NA S Alpha/beta hydrolase family FFAGCILK_01475 543734.LCABL_30150 4.2e-259 900.2 Lactobacillaceae arpJ ko:K02029,ko:K02030,ko:K17073,ko:K17074 ko02010,map02010 M00236,M00589 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.20 iSB619.SA_RS09465 Bacteria 1TPM3@1239,3F48Y@33958,4HAS2@91061,COG0765@1,COG0765@2,COG0834@1,COG0834@2 NA|NA|NA P ABC transporter permease FFAGCILK_01476 543734.LCABL_30160 6.3e-232 809.7 Lactobacillaceae argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 iJN678.argG,iSB619.SA_RS04675 Bacteria 1TP3X@1239,3F46X@33958,4HA1E@91061,COG0137@1,COG0137@2 NA|NA|NA E Belongs to the argininosuccinate synthase family. Type 1 subfamily FFAGCILK_01477 543734.LCABL_30170 5.4e-264 916.4 Lactobacillaceae argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TNZ6@1239,3F4PF@33958,4HB24@91061,COG0165@1,COG0165@2 NA|NA|NA E argininosuccinate lyase FFAGCILK_01478 543734.LCABL_30180 1e-212 745.7 Lactobacillaceae ko:K09963 ko00000 Bacteria 1TRIY@1239,3F4FK@33958,4H9V2@91061,COG3589@1,COG3589@2 NA|NA|NA S Bacterial protein of unknown function (DUF871) FFAGCILK_01479 543734.LCABL_30190 1.6e-73 282.0 Lactobacillaceae Bacteria 1VEZ0@1239,2DQNY@1,337UX@2,3F69F@33958,4HPE2@91061 NA|NA|NA S Domain of unknown function (DUF3284) FFAGCILK_01480 543734.LCABL_30200 3.6e-228 797.3 Lactobacillaceae celB GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006793,GO:0006796,GO:0006810,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0044237,GO:0044238,GO:0044262,GO:0044464,GO:0046835,GO:0051179,GO:0051234,GO:0071702,GO:0071704,GO:0071944,GO:1901264,GO:1902815 2.7.1.207 ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 M00275,M00281 R04393,R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.1,4.A.3.2 iECABU_c1320.ECABU_c19930 Bacteria 1TP8D@1239,3F4VG@33958,4H9W2@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane FFAGCILK_01481 543734.LCABL_30210 1.1e-130 472.6 Lactobacillaceae ko:K03489,ko:K03710,ko:K11922 ko00000,ko03000 Bacteria 1V54P@1239,3F5X0@33958,4IPPI@91061,COG2188@1,COG2188@2 NA|NA|NA K UTRA FFAGCILK_01482 543734.LCABL_30220 2.3e-51 208.0 Lactobacillaceae 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 Bacteria 1VADE@1239,3F6GU@33958,4HKG9@91061,COG1440@1,COG1440@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit FFAGCILK_01483 543734.LCABL_30230 2.4e-53 214.5 Lactobacillaceae chbA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0009987,GO:0015144,GO:0016043,GO:0016740,GO:0016772,GO:0016773,GO:0022607,GO:0022804,GO:0022857,GO:0034219,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0071702,GO:0071840,GO:0090563,GO:0090566,GO:1901264,GO:1902815 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 iECABU_c1320.ECABU_c17610,iECOK1_1307.ECOK1_1683,iECUMN_1333.ECUMN_2025,iNRG857_1313.NRG857_07575,iUMN146_1321.UM146_09345 Bacteria 1VEGE@1239,3F6Z5@33958,4HM37@91061,COG1447@1,COG1447@2 NA|NA|NA G PTS system, Lactose Cellobiose specific IIA subunit FFAGCILK_01484 543734.LCABL_30240 4.1e-106 390.6 Lactobacillaceae speG ko:K07023 ko00000 Bacteria 1V3W1@1239,3F6G6@33958,4HH6A@91061,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain FFAGCILK_01485 543734.LCABL_30250 6.4e-84 316.6 Lactobacillaceae Bacteria 1V5NQ@1239,3F674@33958,4HH6Z@91061,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain FFAGCILK_01486 543734.LCABL_30260 5.6e-89 333.6 Lactobacillaceae Bacteria 1V2CI@1239,3FBXH@33958,4HGAU@91061,COG4639@1,COG4639@2 NA|NA|NA S AAA domain FFAGCILK_01487 543734.LCABL_30270 5.1e-113 413.7 Lactobacillaceae ycaC Bacteria 1V7WN@1239,3F4WV@33958,4HIYX@91061,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family FFAGCILK_01488 543734.LCABL_30280 1.9e-243 848.2 Lactobacillaceae ydiC1 Bacteria 1TPRN@1239,3F5DA@33958,4HBXJ@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major Facilitator Superfamily FFAGCILK_01489 543734.LCABL_30290 2.9e-213 747.7 Lactobacillaceae yeaN GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944 ko:K03449 ko00000,ko02000 2.A.1.17 Bacteria 1TP9R@1239,3F52B@33958,4H9YZ@91061,COG2807@1,COG2807@2 NA|NA|NA P Transporter, major facilitator family protein FFAGCILK_01490 543734.LCABL_30300 2.5e-172 611.3 Lactobacillaceae iolS ko:K06607 ko00000,ko01000 Bacteria 1TPIY@1239,3F40K@33958,4HA4Q@91061,COG0667@1,COG0667@2 NA|NA|NA C Aldo keto reductase FFAGCILK_01491 543734.LCABL_30310 3.4e-64 250.8 Lactobacillaceae manO Bacteria 1V6KV@1239,3F719@33958,4HIMF@91061,COG4687@1,COG4687@2 NA|NA|NA S Domain of unknown function (DUF956) FFAGCILK_01492 543734.LCABL_30320 2.5e-169 601.3 Lactobacillaceae manN ko:K02747,ko:K02796,ko:K02815,ko:K17467 ko00030,ko00051,ko00052,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00052,map00520,map01100,map01120,map02060 M00276,M00277,M00278,M00610 R02630,R04076,R08366,R10407 RC00017,RC01069,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.17,4.A.6.1.3,4.A.6.1.4 Bacteria 1TQA3@1239,3F3KR@33958,4HA3K@91061,COG3716@1,COG3716@2 NA|NA|NA G system, mannose fructose sorbose family IID component FFAGCILK_01493 543734.LCABL_30330 8.7e-121 439.9 Lactobacillaceae manY ko:K02795,ko:K02796,ko:K02814 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276,M00278 R02630,R04076 RC00017,RC01069,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.3 Bacteria 1TPKK@1239,3F3V5@33958,4H9QI@91061,COG3715@1,COG3715@2 NA|NA|NA G PTS system FFAGCILK_01494 543734.LCABL_30340 8.1e-182 642.9 Lactobacillaceae manL 2.7.1.191,2.7.1.206 ko:K02793,ko:K02794,ko:K02812 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276,M00278 R02630,R04076 RC00017,RC01069,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1,4.A.6.1.3 Bacteria 1TQJ4@1239,3F4PU@33958,4H9Z8@91061,COG2893@1,COG2893@2,COG3444@1,COG3444@2 NA|NA|NA G PTS system sorbose subfamily IIB component FFAGCILK_01495 543734.LCABL_30350 1.3e-219 768.8 Bacilli Bacteria 1UM0A@1239,4ITNK@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily FFAGCILK_01497 543734.LCABL_30360 2.4e-150 538.1 Lactobacillaceae Bacteria 1V9XM@1239,3F79A@33958,4HJUU@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins FFAGCILK_01498 387344.LVIS_0121 3.5e-174 617.5 Lactobacillaceae ko:K07482 ko00000 Bacteria 1TRSF@1239,3F3WY@33958,4HTRR@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family FFAGCILK_01499 543734.LCABL_30370 1.1e-150 539.3 Lactobacillaceae ko:K20373 ko02024,map02024 ko00000,ko00001,ko03000 Bacteria 1W2GY@1239,3F8YW@33958,4IGZ7@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins FFAGCILK_01500 543734.LCABL_30380 1.1e-158 565.8 Lactobacillaceae Bacteria 1VD8E@1239,3F3QV@33958,4HMD2@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins FFAGCILK_01502 543734.LCABL_30400 4e-287 993.4 Lactobacillaceae glnP ko:K02029,ko:K02030,ko:K17073,ko:K17074 ko02010,map02010 M00236,M00589 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.20 Bacteria 1TPM3@1239,3F48Y@33958,4HAS2@91061,COG0765@1,COG0765@2,COG0834@1,COG0834@2 NA|NA|NA P ABC transporter permease FFAGCILK_01503 543734.LCABL_30410 3.1e-133 481.1 Lactobacillaceae glnQ ko:K17074,ko:K17076 ko02010,map02010 M00589 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.20 Bacteria 1TNYD@1239,3F3QQ@33958,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein FFAGCILK_01504 568703.LGG_02850 3.4e-31 140.6 Lactobacillaceae Bacteria 1U7RB@1239,2AHQJ@1,3182T@2,3FA24@33958,4IHNN@91061 NA|NA|NA FFAGCILK_01505 543734.LCABL_30430 4e-237 827.0 Bacilli ko:K02027,ko:K05813 ko02010,map02010 M00198,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3 Bacteria 1TR68@1239,4HX7S@91061,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein FFAGCILK_01506 543734.LCABL_30440 1.5e-129 468.8 Lactobacillaceae Bacteria 1VCPB@1239,3F69G@33958,4HN1D@91061,COG5523@1,COG5523@2 NA|NA|NA S Protein of unknown function (DUF975) FFAGCILK_01507 1423732.BALS01000133_gene400 4.9e-41 173.7 Lactobacillaceae yqkB Bacteria 1U783@1239,3F93I@33958,4IH2X@91061,COG4918@1,COG4918@2 NA|NA|NA S Iron-sulphur cluster biosynthesis FFAGCILK_01508 543734.LCABL_30470 3.4e-52 210.7 Lactobacillaceae Bacteria 1W3JF@1239,298U1@1,2ZVY8@2,3F7JE@33958,4I1SS@91061 NA|NA|NA FFAGCILK_01509 543734.LCABL_30480 2.9e-68 264.6 Lactobacillaceae ko:K09167 ko00000 Bacteria 1VFTS@1239,3F6GM@33958,4HGMB@91061,COG3402@1,COG3402@2 NA|NA|NA S Bacterial PH domain FFAGCILK_01510 543734.LCABL_30490 6.3e-269 932.9 Lactobacillaceae ydbT ko:K08981 ko00000 Bacteria 1TSRJ@1239,3F3VB@33958,4HB8P@91061,COG3428@1,COG3428@2 NA|NA|NA S Bacterial PH domain FFAGCILK_01511 543734.LCABL_30500 1.4e-144 518.8 Lactobacillaceae Bacteria 1TSWP@1239,3F8H5@33958,4HBQT@91061,COG3910@1,COG3910@2 NA|NA|NA S AAA ATPase domain FFAGCILK_01512 543734.LCABL_30510 1.7e-167 595.1 Lactobacillaceae yniA GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 Bacteria 1U79A@1239,3F3RK@33958,4HAZS@91061,COG3001@1,COG3001@2 NA|NA|NA G Phosphotransferase enzyme family FFAGCILK_01513 543734.LCABL_30520 3.4e-132 477.6 Lactobacillaceae glnQ 3.6.3.21 ko:K02028,ko:K10038 ko02010,map02010 M00227,M00236 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.2 Bacteria 1TNYD@1239,3F3QQ@33958,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein FFAGCILK_01514 543734.LCABL_30530 1.5e-264 918.3 Lactobacillaceae glnP ko:K02029,ko:K02030,ko:K17073,ko:K17074 ko02010,map02010 M00236,M00589 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.20 Bacteria 1TQUG@1239,3F4HA@33958,4HAJ5@91061,COG0765@1,COG0765@2,COG0834@1,COG0834@2 NA|NA|NA P ABC transporter FFAGCILK_01515 543734.LCABL_30540 8e-266 922.5 Lactobacillaceae glnP ko:K02029,ko:K02030,ko:K17073,ko:K17074 ko02010,map02010 M00236,M00589 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.20 Bacteria 1TQUG@1239,3F4HA@33958,4HAJ5@91061,COG0765@1,COG0765@2,COG0834@1,COG0834@2 NA|NA|NA P ABC transporter FFAGCILK_01516 543734.LCABL_30550 3.7e-99 367.5 Lactobacillaceae ydaF ko:K03817 ko00000,ko01000,ko03009 Bacteria 1V3NE@1239,3F6YW@33958,4HG1N@91061,COG1670@1,COG1670@2 NA|NA|NA J Acetyltransferase (GNAT) domain FFAGCILK_01517 543734.LCABL_30560 3.6e-106 391.0 Lactobacillaceae ko:K06384 ko00000 Bacteria 1VFG7@1239,3F7WH@33958,4IRI6@91061,COG1300@1,COG1300@2 NA|NA|NA S Stage II sporulation protein M FFAGCILK_01518 1423816.BACQ01000031_gene1278 2.1e-142 511.9 Lactobacillaceae yeaC GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 ko:K03924 ko00000,ko01000 Bacteria 1TPKR@1239,3F59F@33958,4HA0T@91061,COG0714@1,COG0714@2 NA|NA|NA S ATPase family associated with various cellular activities (AAA) FFAGCILK_01519 543734.LCABL_30590 1.5e-183 648.7 Lactobacillaceae yeaD Bacteria 1VNZZ@1239,3F8YE@33958,4IGYV@91061,COG1721@1,COG1721@2 NA|NA|NA S Protein of unknown function DUF58 FFAGCILK_01520 543734.LCABL_30610 0.0 1080.9 Lactobacillaceae yebA Bacteria 1TP8K@1239,3F5PB@33958,4HB2E@91061,COG1305@1,COG1305@2 NA|NA|NA E Transglutaminase/protease-like homologues FFAGCILK_01521 543734.LCABL_30620 9.2e-214 749.2 Lactobacillaceae lsgC Bacteria 1TPHK@1239,3F5EZ@33958,4HAXV@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 FFAGCILK_01522 543734.LCABL_30630 4.8e-90 337.4 Lactobacillaceae maa 2.3.1.79 ko:K00661 ko00000,ko01000 Bacteria 1TQEX@1239,3FBEM@33958,4HGH2@91061,COG0110@1,COG0110@2 NA|NA|NA S Maltose acetyltransferase FFAGCILK_01523 543734.LCABL_30640 1.7e-145 521.9 Lactobacillaceae 3.1.3.102,3.1.3.104 ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00548,R07280 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1UYU8@1239,3F3ZW@33958,4HE0K@91061,COG0561@1,COG0561@2 NA|NA|NA G Sucrose-6F-phosphate phosphohydrolase FFAGCILK_01524 543734.LCABL_30650 2.7e-255 887.5 Lactobacillaceae aspA 4.2.1.2,4.3.1.1 ko:K01679,ko:K01744 ko00020,ko00250,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00250,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R00490,R01082 RC00316,RC00443,RC02799 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP3U@1239,3FBTC@33958,4HFM9@91061,COG1027@1,COG1027@2 NA|NA|NA E Fumarase C C-terminus FFAGCILK_01525 543734.LCABL_30660 9.7e-114 416.0 Lactobacillaceae Bacteria 1VCMU@1239,3F68B@33958,4HN16@91061,COG4430@1,COG4430@2 NA|NA|NA S Bacteriocin-protection, YdeI or OmpD-Associated FFAGCILK_01526 568703.LGG_02874 9.9e-36 156.4 Lactobacillaceae yjdF Bacteria 1V2J3@1239,28NY7@1,2ZBVG@2,3F6EY@33958,4HMY0@91061 NA|NA|NA S Protein of unknown function (DUF2992) FFAGCILK_01527 543734.LCABL_30690 1.8e-212 745.0 Lactobacillaceae mez_1 1.1.1.38 ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 R00214 RC00105 ko00000,ko00001,ko01000 Bacteria 1TPJ3@1239,3F4GN@33958,4H9WR@91061,COG0281@1,COG0281@2 NA|NA|NA C Malic enzyme, NAD binding domain FFAGCILK_01528 543734.LCABL_30700 4e-224 783.9 Lactobacillaceae maeN ko:K11616 ko02020,map02020 ko00000,ko00001 2.A.24.2 Bacteria 1TR97@1239,3F61N@33958,4HBS8@91061,COG3493@1,COG3493@2 NA|NA|NA C 2-hydroxycarboxylate transporter family FFAGCILK_01529 543734.LCABL_30710 5.4e-289 999.6 Lactobacillaceae dpiB 2.7.13.3 ko:K02476,ko:K07706,ko:K11614 ko02020,ko02024,map02020,map02024 M00490,M00495 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TQJR@1239,3F62P@33958,4H9Q0@91061,COG3290@1,COG3290@2 NA|NA|NA T Single cache domain 3 FFAGCILK_01530 543734.LCABL_30720 1.1e-121 442.6 Lactobacillaceae dpiA ko:K02475,ko:K11615 ko02020,map02020 M00490 ko00000,ko00001,ko00002,ko02022 Bacteria 1V3PK@1239,3F702@33958,4HGXB@91061,COG4565@1,COG4565@2 NA|NA|NA KT cheY-homologous receiver domain FFAGCILK_01531 543734.LCABL_30730 1.1e-144 519.2 Lactobacillaceae 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 R05066 RC00099 ko00000,ko00001,ko01000 Bacteria 1U5HC@1239,3F5Y9@33958,4IF86@91061,COG2084@1,COG2084@2 NA|NA|NA I NAD binding domain of 6-phosphogluconate dehydrogenase FFAGCILK_01532 543734.LCABL_30740 4.4e-94 350.5 Lactobacillaceae M1-431 Bacteria 1TSF1@1239,3F6U6@33958,4HHG3@91061,COG4283@1,COG4283@2 NA|NA|NA S Protein of unknown function (DUF1706) FFAGCILK_01535 543734.LCABL_30750 6.3e-64 250.0 Lactobacillaceae Bacteria 1U5V4@1239,29NYR@1,309WU@2,3F6J0@33958,4IFIS@91061 NA|NA|NA FFAGCILK_01536 543734.LCABL_30760 7.2e-210 736.5 Lactobacillaceae yagE Bacteria 1VTJD@1239,3FCAK@33958,4HTEM@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease FFAGCILK_01537 543734.LCABL_30770 1.3e-168 599.0 Lactobacillaceae Bacteria 1TPCZ@1239,3F4I6@33958,4HC7A@91061,COG0826@1,COG0826@2 NA|NA|NA O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity FFAGCILK_01538 1423816.BACQ01000031_gene1259 4.6e-226 790.4 Lactobacillaceae ptsG ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 Bacteria 1TP5X@1239,3F458@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2 NA|NA|NA G phosphotransferase system FFAGCILK_01539 1293597.BN147_01560 2.6e-40 171.8 Lactobacillaceae pts23A ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1 Bacteria 1VAEB@1239,3FC0X@33958,4HIPR@91061,COG2190@1,COG2190@2 NA|NA|NA G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 FFAGCILK_01540 1423816.BACQ01000031_gene1258 1.3e-117 429.5 Lactobacillaceae ko:K02538,ko:K03488 ko00000,ko03000 Bacteria 1TT5A@1239,3F4SJ@33958,4HC5Y@91061,COG3711@1,COG3711@2 NA|NA|NA K CAT RNA binding domain FFAGCILK_01541 568703.LGG_02885 1.3e-223 781.9 Lactobacillaceae sip Bacteria 1TTJI@1239,3F4IB@33958,4HDG6@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family FFAGCILK_01542 1104325.M7W_1969 2.3e-07 62.8 Enterococcaceae ko:K07727 ko00000,ko03000 Bacteria 1VESP@1239,4B40C@81852,4HKR7@91061,COG3655@1,COG3655@2 NA|NA|NA K Cro/C1-type HTH DNA-binding domain FFAGCILK_01543 1423816.BACQ01000022_gene758 2.7e-37 161.0 Lactobacillaceae Bacteria 1U7ZA@1239,2BNWZ@1,32HKX@2,3FACM@33958,4IHWN@91061 NA|NA|NA FFAGCILK_01544 568703.LGG_02888 3.3e-30 137.1 Lactobacillaceae Bacteria 1U81M@1239,2BPNT@1,32IFV@2,3FAF0@33958,4IHZ0@91061 NA|NA|NA FFAGCILK_01545 568703.LGG_02889 4.2e-12 76.3 Lactobacillaceae Bacteria 1U84R@1239,29QI2@1,30BHH@2,3FAIV@33958,4II26@91061 NA|NA|NA FFAGCILK_01546 543734.LCABL_30840 1e-24 118.6 Lactobacillaceae Bacteria 1U8DG@1239,29QP0@1,30BNN@2,3FAV3@33958,4IIBE@91061 NA|NA|NA FFAGCILK_01547 1423732.BALS01000058_gene2818 3.2e-35 154.1 Lactobacillaceae Bacteria 1U7TH@1239,29QB8@1,30BAG@2,3FA5K@33958,4IHQZ@91061 NA|NA|NA FFAGCILK_01548 543734.LCABL_30860 4.4e-07 60.1 Lactobacillaceae Bacteria 1U847@1239,2AIKE@1,3192N@2,3FAIA@33958,4II1N@91061 NA|NA|NA FFAGCILK_01549 568703.LGG_02893 1.2e-157 562.4 Lactobacillaceae Bacteria 1VVT1@1239,3FBJ8@33958,4ITNM@91061,COG3598@1,COG3598@2 NA|NA|NA L Bifunctional DNA primase/polymerase, N-terminal FFAGCILK_01550 568703.LGG_02894 8.3e-276 955.7 Lactobacillaceae Bacteria 1TQNX@1239,3F4EZ@33958,4HCHZ@91061,COG5545@1,COG5545@2 NA|NA|NA S Virulence-associated protein E FFAGCILK_01551 568703.LGG_02895 1.6e-73 282.0 Lactobacillaceae Bacteria 1U772@1239,30AWJ@2,3F924@33958,4IH1W@91061,arCOG11762@1 NA|NA|NA FFAGCILK_01552 568703.LGG_02897 5.3e-78 297.0 Lactobacillaceae terS Bacteria 1VJ8S@1239,3F4WP@33958,4HQ9R@91061,COG3747@1,COG3747@2 NA|NA|NA L Phage terminase, small subunit FFAGCILK_01553 568703.LGG_02898 6.4e-307 1059.3 Lactobacillaceae terL Bacteria 1TPU1@1239,3F51U@33958,4HAXI@91061,COG4626@1,COG4626@2 NA|NA|NA S overlaps another CDS with the same product name FFAGCILK_01554 568703.LGG_02899 3.9e-21 106.7 Lactobacillaceae Bacteria 1U8EJ@1239,2BTIA@1,32NQT@2,3FAWA@33958,4IICE@91061 NA|NA|NA FFAGCILK_01555 568703.LGG_02900 2.2e-221 774.6 Lactobacillaceae Bacteria 1TP8B@1239,3F42D@33958,4HHWD@91061,COG4695@1,COG4695@2 NA|NA|NA S Phage portal protein FFAGCILK_01556 568703.LGG_02901 1.1e-270 938.7 Lactobacillaceae ko:K06904 ko00000 Bacteria 1TSYM@1239,3F5ZB@33958,4HE4V@91061,COG3740@1,COG3740@2,COG4653@1,COG4653@2 NA|NA|NA S Phage capsid family FFAGCILK_01557 568703.LGG_02902 3.3e-46 190.7 Bacilli Bacteria 1W1M4@1239,28TB1@1,2ZIBE@2,4I0N3@91061 NA|NA|NA S Phage gp6-like head-tail connector protein FFAGCILK_01558 1196324.A374_08749 7.4e-13 80.1 Firmicutes Bacteria 1W3UJ@1239,2C6FI@1,2ZGHD@2 NA|NA|NA S Phage head-tail joining protein FFAGCILK_01559 543734.LCABL_30970 2.9e-16 90.1 Lactobacillaceae Bacteria 1U6PB@1239,2A7T8@1,30WSA@2,3F8SR@33958,4IGGB@91061 NA|NA|NA FFAGCILK_01560 1423732.BALS01000106_gene437 2.2e-14 84.7 Lactobacillaceae ytgB Bacteria 1VENK@1239,3F7EK@33958,4HNKV@91061,COG2261@1,COG2261@2 NA|NA|NA S Transglycosylase associated protein FFAGCILK_01562 543734.LCABL_31000 3e-170 604.4 Lactobacillaceae prs 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2848 Bacteria 1TQ6Q@1239,3F3V8@33958,4HB61@91061,COG0462@1,COG0462@2 NA|NA|NA F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) FFAGCILK_01563 543734.LCABL_31010 6.6e-181 639.8 Lactobacillaceae ko:K06889 ko00000 Bacteria 1TQYU@1239,3F43H@33958,4HC4H@91061,COG1073@1,COG1073@2 NA|NA|NA D Alpha beta FFAGCILK_01564 543734.LCABL_31020 1.8e-186 658.3 Lactobacillaceae lipA Bacteria 1V2AW@1239,3F3N7@33958,4HU2V@91061,COG0657@1,COG0657@2 NA|NA|NA I Carboxylesterase family FFAGCILK_01565 543734.LCABL_31030 5.1e-207 726.9 Lactobacillaceae mtlD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006059,GO:0006066,GO:0008150,GO:0008152,GO:0008926,GO:0009056,GO:0009987,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019400,GO:0019405,GO:0019407,GO:0019592,GO:0019594,GO:0019751,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0055114,GO:0071704,GO:1901575,GO:1901615,GO:1901616 1.1.1.17 ko:K00009 ko00051,map00051 R02703 RC00085 ko00000,ko00001,ko01000 iSBO_1134.SBO_3598,iSbBS512_1146.SbBS512_E4017 Bacteria 1TPZU@1239,3F448@33958,4H9S3@91061,COG0246@1,COG0246@2 NA|NA|NA C mannitol-1-phosphate 5-dehydrogenase activity FFAGCILK_01566 543734.LCABL_31040 1.1e-77 295.8 Lactobacillaceae mtlF 2.7.1.197 ko:K02798,ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 M00274 R02704 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5 Bacteria 1V77P@1239,3F6EP@33958,4HIM2@91061,COG4668@1,COG4668@2 NA|NA|NA G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane FFAGCILK_01567 543734.LCABL_31050 0.0 1302.7 Lactobacillaceae mtlR ko:K03483 ko00000,ko03000 Bacteria 1TQT1@1239,3F561@33958,4HABH@91061,COG3711@1,COG3711@2 NA|NA|NA K Mga helix-turn-helix domain FFAGCILK_01568 543734.LCABL_31060 0.0 1156.0 Lactobacillaceae mtlA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.197 ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 M00274 R02704 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5 Bacteria 1TPE3@1239,3F52S@33958,4HAVV@91061,COG2213@1,COG2213@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit FFAGCILK_01569 543734.LCABL_31070 6.9e-130 469.9 Lactobacillaceae nagB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0008150,GO:0008152,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135 3.1.1.31,3.5.99.6 ko:K01057,ko:K02564 ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R00765,R02035 RC00163,RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP10@1239,3F3NR@33958,4HAG4@91061,COG0363@1,COG0363@2 NA|NA|NA G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion FFAGCILK_01570 543734.LCABL_31080 3.3e-149 534.3 Lactobacillaceae Bacteria 1TSZZ@1239,3F49K@33958,4HB54@91061,COG0561@1,COG0561@2 NA|NA|NA S haloacid dehalogenase-like hydrolase FFAGCILK_01571 568703.LGG_02915 3.1e-43 180.6 Lactobacillaceae Bacteria 1U774@1239,29PY5@1,30AWK@2,3F926@33958,4IH1Y@91061 NA|NA|NA FFAGCILK_01572 1423732.BALS01000029_gene2260 5.2e-10 69.7 Lactobacillaceae Bacteria 1U8EV@1239,2BZTI@1,302JZ@2,3FAWN@33958,4IICR@91061 NA|NA|NA FFAGCILK_01573 543734.LCABL_31120 4.3e-184 650.6 Lactobacillaceae bacG ko:K02005 ko00000 Bacteria 1TT2M@1239,3F5MV@33958,4HG99@91061,COG0845@1,COG0845@2 NA|NA|NA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family FFAGCILK_01574 543734.LCABL_31130 1.1e-124 452.6 Lactobacillaceae ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPBJ@1239,3F4CA@33958,4HFUH@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter FFAGCILK_01575 543734.LCABL_31140 6.2e-208 729.9 Lactobacillaceae bacI ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPUU@1239,3F5FN@33958,4HBY9@91061,COG0577@1,COG0577@2 NA|NA|NA V MacB-like periplasmic core domain FFAGCILK_01576 543734.LCABL_31180 3.2e-181 641.0 Lactobacillaceae amd 3.5.1.47 ko:K01436,ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TPD7@1239,3FC42@33958,4H9WQ@91061,COG1473@1,COG1473@2 NA|NA|NA E Peptidase family M20/M25/M40 FFAGCILK_01577 543734.LCABL_31190 2.6e-80 304.7 Lactobacillaceae Bacteria 1V6P0@1239,3F706@33958,4HJ1Y@91061,COG3610@1,COG3610@2 NA|NA|NA S Threonine/Serine exporter, ThrE FFAGCILK_01578 543734.LCABL_31200 4.5e-135 487.3 Lactobacillaceae thrE Bacteria 1TSE8@1239,3F4XE@33958,4HBW1@91061,COG2966@1,COG2966@2 NA|NA|NA S Putative threonine/serine exporter FFAGCILK_01580 543734.LCABL_31220 0.0 1251.9 Lactobacillaceae gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 ko:K03495 R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 Bacteria 1TQ4B@1239,3F454@33958,4HA6S@91061,COG0445@1,COG0445@2 NA|NA|NA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 FFAGCILK_01581 543734.LCABL_31230 2.1e-252 877.9 Lactobacillaceae mnmE GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K03650 R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 Bacteria 1TPJF@1239,3F3WA@33958,4HA06@91061,COG0486@1,COG0486@2 NA|NA|NA S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 FFAGCILK_01583 543734.LCABL_31240 8.2e-129 466.5 Lactobacillaceae jag ko:K06346 ko00000 Bacteria 1V3IN@1239,3F5WG@33958,4HHHU@91061,COG1847@1,COG1847@2 NA|NA|NA S R3H domain protein FFAGCILK_01584 543734.LCABL_31250 2.6e-136 491.5 Lactobacillaceae yidC ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 1TQ0J@1239,3F3SD@33958,4HB3J@91061,COG0706@1,COG0706@2 NA|NA|NA U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins FFAGCILK_01585 543734.LCABL_31260 2.1e-59 235.3 Lactobacillaceae rnpA GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536,ko:K08998 ko00000,ko01000,ko03016 Bacteria 1VA78@1239,3F6GS@33958,4HKG6@91061,COG0594@1,COG0594@2 NA|NA|NA J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme FFAGCILK_01586 543734.LCABL_31270 1.1e-15 88.2 Lactobacillaceae rpmH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02914 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VK90@1239,3F81W@33958,4HR2Z@91061,COG0230@1,COG0230@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL34 family FFAGCILK_01587 543734.LCABL_00010 1.2e-252 878.6 Lactobacillaceae dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 Bacteria 1TPV7@1239,3F3YA@33958,4H9MW@91061,COG0593@1,COG0593@2 NA|NA|NA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids FFAGCILK_01588 543734.LCABL_00020 5.2e-204 716.8 Lactobacillaceae dnaN 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TQ7J@1239,3F3ZQ@33958,4H9TF@91061,COG0592@1,COG0592@2 NA|NA|NA L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria FFAGCILK_01590 543734.LCABL_00030 1.7e-31 141.4 Lactobacillaceae yaaA GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K14761 ko00000,ko03009 Bacteria 1VEJ2@1239,3F803@33958,4HNMC@91061,COG2501@1,COG2501@2 NA|NA|NA S S4 domain protein YaaA FFAGCILK_01591 543734.LCABL_00040 2.5e-203 714.5 Lactobacillaceae recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1TP9U@1239,3F3Q1@33958,4HA0W@91061,COG1195@1,COG1195@2 NA|NA|NA L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP FFAGCILK_01592 543734.LCABL_00050 0.0 1295.4 Lactobacillaceae gyrB GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02470,ko:K02622 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1TQ0R@1239,3F48M@33958,4H9Y6@91061,COG0187@1,COG0187@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner FFAGCILK_01593 543734.LCABL_00060 0.0 1634.0 Lactobacillaceae gyrA GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02469,ko:K02621 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1TP2Z@1239,3F3YM@33958,4HAHY@91061,COG0188@1,COG0188@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner FFAGCILK_01594 543734.LCABL_00070 2.7e-126 458.0 Lactobacillaceae deoC GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 ko:K01619 ko00030,map00030 R01066 RC00436,RC00437 ko00000,ko00001,ko01000 Bacteria 1TPAJ@1239,3F4M3@33958,4HAAJ@91061,COG0274@1,COG0274@2 NA|NA|NA F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate FFAGCILK_01595 543734.LCABL_00080 8.5e-75 286.2 Bacilli ssb_2 ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 1V3WT@1239,4HH8I@91061,COG0629@1,COG0629@2 NA|NA|NA L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism FFAGCILK_01596 543734.LCABL_00090 5.5e-49 199.9 Lactobacillaceae rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 ko:K02990 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1VA18@1239,3F6ZY@33958,4HKHD@91061,COG0360@1,COG0360@2 NA|NA|NA J Binds together with S18 to 16S ribosomal RNA FFAGCILK_01597 543734.LCABL_00100 5.3e-67 260.8 Lactobacillaceae ssb ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 1V3WT@1239,3F66N@33958,4HH8I@91061,COG0629@1,COG0629@2 NA|NA|NA L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism FFAGCILK_01598 1423732.BALS01000057_gene2844 1.2e-35 155.2 Lactobacillaceae rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02963,ko:K03111,ko:K15125 ko03010,ko03030,ko03430,ko03440,ko05133,map03010,map03030,map03430,map03440,map05133 M00178 br01610,ko00000,ko00001,ko00002,ko00536,ko03011,ko03029,ko03032,ko03400 Bacteria 1V9XS@1239,3F7CY@33958,4HKCC@91061,COG0238@1,COG0238@2 NA|NA|NA J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit FFAGCILK_01599 543734.LCABL_00140 5.6e-283 979.5 Lactobacillaceae cydA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iPC815.YPO1117,iSBO_1134.SBO_2253,iSFxv_1172.SFxv_0621,iS_1188.S0577,iSbBS512_1146.SbBS512_E2337 Bacteria 1TRH4@1239,3F5E6@33958,4HA19@91061,COG1271@1,COG1271@2 NA|NA|NA C Cytochrome bd terminal oxidase subunit I FFAGCILK_01600 543734.LCABL_00150 4.8e-177 627.1 Lactobacillaceae cydB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iECABU_c1320.ECABU_c10120,iLF82_1304.LF82_0101,iNRG857_1313.NRG857_04455,iPC815.YPO1118,ic_1306.c1120 Bacteria 1TRYV@1239,3F3ZH@33958,4H9KF@91061,COG1294@1,COG1294@2 NA|NA|NA C Cytochrome bd terminal oxidase subunit II FFAGCILK_01601 543734.LCABL_00160 7.4e-26 122.5 Lactobacillaceae Bacteria 1U6T8@1239,2B5YU@1,31YUW@2,3F8G7@33958,4IGM0@91061 NA|NA|NA FFAGCILK_01602 543734.LCABL_00170 1.3e-105 389.0 Lactobacillaceae Bacteria 1VFW9@1239,3F4JD@33958,4HR1J@91061,COG3548@1,COG3548@2 NA|NA|NA S Protein of unknown function (DUF1211) FFAGCILK_01605 543734.LCABL_00200 4.2e-139 500.7 Lactobacillaceae ko:K07052 ko00000 Bacteria 1VA8S@1239,3F5HF@33958,4HPR4@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity FFAGCILK_01609 543734.LCABL_00230 8.6e-112 410.6 Lactobacillaceae usp 3.5.1.28 ko:K21471,ko:K22409 ko00000,ko01000,ko01002,ko01011 CBM50 Bacteria 1VCXB@1239,3F4ZY@33958,4HMCB@91061,COG3942@1,COG3942@2,COG4942@1,COG4942@2 NA|NA|NA D CHAP domain FFAGCILK_01610 543734.LCABL_00240 0.0 1577.0 Lactobacillaceae ylbB ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPHU@1239,3F4HF@33958,4HA2C@91061,COG0577@1,COG0577@2 NA|NA|NA V ABC transporter permease FFAGCILK_01611 543734.LCABL_00250 2.8e-128 464.5 Lactobacillaceae macB ko:K02003,ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQC9@1239,3F3YU@33958,4HB8D@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein FFAGCILK_01612 543734.LCABL_00260 5.4e-98 363.6 Lactobacillaceae Bacteria 1VI1M@1239,3F530@33958,4HPZV@91061,COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator FFAGCILK_01613 543734.LCABL_00270 5.4e-155 553.5 Lactobacillaceae supH Bacteria 1UYU8@1239,3F3ZW@33958,4HE0K@91061,COG0561@1,COG0561@2 NA|NA|NA G Sucrose-6F-phosphate phosphohydrolase FFAGCILK_01614 543734.LCABL_00280 2.1e-49 201.4 Lactobacillaceae Bacteria 1U6YE@1239,29PRI@1,30APR@2,3F8Q9@33958,4IGSK@91061 NA|NA|NA FFAGCILK_01617 543734.LCABL_00300 0.0 1407.5 Lactobacillaceae ybfG Bacteria 1TPV1@1239,3F5J4@33958,4HCRA@91061,COG3409@1,COG3409@2 NA|NA|NA M peptidoglycan-binding domain-containing protein FFAGCILK_01618 568703.LGG_00037 4.7e-124 450.7 Lactobacillaceae ko:K07090 ko00000 Bacteria 1VR9G@1239,3F3TR@33958,4HV4W@91061,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein FFAGCILK_01619 543734.LCABL_00320 2e-101 375.2 Lactobacillaceae Bacteria 1V803@1239,3F6KM@33958,4IRHS@91061,COG3548@1,COG3548@2 NA|NA|NA S Protein of unknown function (DUF1211) FFAGCILK_01620 543734.LCABL_00330 2e-163 581.6 Lactobacillaceae corA ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria 1TPI8@1239,3F4B8@33958,4HE7S@91061,COG0598@1,COG0598@2 NA|NA|NA P CorA-like Mg2+ transporter protein FFAGCILK_01621 543734.LCABL_00340 1.2e-112 412.5 Lactobacillaceae Bacteria 1V3R8@1239,3F75F@33958,4HBEK@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family FFAGCILK_01626 543734.LCABL_00360 7.5e-242 842.8 Lactobacillaceae mntH GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 ko:K03322 ko00000,ko02000 2.A.55.2.6,2.A.55.3 Bacteria 1TPT1@1239,3F49Y@33958,4HAEA@91061,COG1914@1,COG1914@2 NA|NA|NA P H( )-stimulated, divalent metal cation uptake system FFAGCILK_01627 543734.LCABL_00370 9.9e-50 202.6 Lactobacillaceae Bacteria 1U7Q9@1239,29Q91@1,30B85@2,3FA0E@33958,4IHMK@91061 NA|NA|NA FFAGCILK_01629 1140001.I571_00212 1.4e-42 180.3 Enterococcaceae Bacteria 1UZI0@1239,4AZI4@81852,4HZ6P@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins FFAGCILK_01630 543734.LCABL_00390 7.3e-288 995.7 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase FFAGCILK_01631 543734.LCABL_00400 8e-106 389.8 Lactobacillaceae Bacteria 1VQW3@1239,3F64W@33958,4HV4F@91061,COG2364@1,COG2364@2 NA|NA|NA S Membrane FFAGCILK_01632 543734.LCABL_00430 3.4e-83 314.3 Lactobacillaceae Bacteria 1U8KU@1239,29QSZ@1,30BSU@2,3FB3B@33958,4IIIV@91061 NA|NA|NA FFAGCILK_01633 543734.LCABL_00440 2.6e-13 81.6 Lactobacillaceae Bacteria 1U7S8@1239,2BM2D@1,32FJC@2,3FA3P@33958,4IHPK@91061 NA|NA|NA FFAGCILK_01634 485916.Dtox_1835 9e-44 183.7 Clostridia Bacteria 1TSQU@1239,24F7K@186801,28J1N@1,2Z8YI@2 NA|NA|NA S Nucleotidyl transferase AbiEii toxin, Type IV TA system FFAGCILK_01635 945021.TEH_04260 1.6e-76 292.7 Firmicutes Bacteria 1VAA9@1239,28KWY@1,2ZAD1@2 NA|NA|NA FFAGCILK_01636 543734.LCABL_00470 1.2e-121 442.6 Lactobacillaceae azlC Bacteria 1U49T@1239,3F45S@33958,4HDIJ@91061,COG1296@1,COG1296@2 NA|NA|NA E branched-chain amino acid FFAGCILK_01637 543734.LCABL_00480 7.3e-50 203.0 Lactobacillaceae azlD Bacteria 1VH9Q@1239,3F7IU@33958,4HNDZ@91061,COG4392@1,COG4392@2 NA|NA|NA S Branched-chain amino acid transport protein (AzlD) FFAGCILK_01639 543734.LCABL_00510 3.2e-144 517.7 Lactobacillaceae ko:K07052 ko00000 Bacteria 1VA8S@1239,3F5HF@33958,4HPR4@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity FFAGCILK_01640 543734.LCABL_00520 3.4e-115 421.0 Lactobacillaceae eda 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 Bacteria 1TS0F@1239,3F6AY@33958,4HG4G@91061,COG0800@1,COG0800@2 NA|NA|NA G KDPG and KHG aldolase FFAGCILK_01641 543734.LCABL_00540 1.3e-125 455.7 Lactobacillaceae kdgR Bacteria 1V3SB@1239,3F69H@33958,4HGG8@91061,COG1802@1,COG1802@2 NA|NA|NA K FCD domain FFAGCILK_01643 543734.LCABL_00550 2.1e-54 218.0 Lactobacillaceae Bacteria 1VFF0@1239,2E9Y3@1,3343R@2,3F8BC@33958,4HPUY@91061 NA|NA|NA FFAGCILK_01644 543734.LCABL_00560 2.9e-93 347.8 Lactobacillaceae Bacteria 1UZI0@1239,3F837@33958,4I40C@91061,COG1396@1,COG1396@2 NA|NA|NA K Transcriptional activator, Rgg GadR MutR family FFAGCILK_01645 543734.LCABL_00560 9.6e-45 186.0 Lactobacillaceae Bacteria 1UZI0@1239,3F837@33958,4I40C@91061,COG1396@1,COG1396@2 NA|NA|NA K Transcriptional activator, Rgg GadR MutR family FFAGCILK_01646 543734.LCABL_00570 1.9e-284 984.6 Lactobacillaceae ko:K06147,ko:K06148 ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TSRV@1239,3F46B@33958,4HCIZ@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC-type multidrug transport system, ATPase and permease components FFAGCILK_01647 543734.LCABL_00580 2.4e-240 837.8 Lactobacillaceae ko:K18926 M00715 ko00000,ko00002,ko02000 2.A.1.3.30 Bacteria 1UYQB@1239,3F3NG@33958,4HE3Y@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily FFAGCILK_01648 543734.LCABL_00590 4.2e-50 203.8 Lactobacillaceae ko:K15773 ko00000,ko02048,ko03000 Bacteria 1W30D@1239,3F8T4@33958,4I0AB@91061,COG1476@1,COG1476@2 NA|NA|NA K TRANSCRIPTIONal FFAGCILK_01649 543734.LCABL_00600 0.0 1282.3 Lactobacillaceae ydgH GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006790,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0030312,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044272,GO:0044281,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046505,GO:0046506,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:1901576 ko:K06994,ko:K07003 ko00000 Bacteria 1TQ7C@1239,3FCCY@33958,4HBM6@91061,COG1511@1,COG1511@2,COG2409@1,COG2409@2 NA|NA|NA S MMPL family FFAGCILK_01650 543734.LCABL_00610 7.4e-109 399.8 Lactobacillaceae ko:K22106 ko00000,ko03000 Bacteria 1V95E@1239,3F6ZH@33958,4HH9M@91061,COG1309@1,COG1309@2 NA|NA|NA K Tetracycline repressor, C-terminal all-alpha domain FFAGCILK_01652 543734.LCABL_00630 3.3e-110 404.4 Lactobacillaceae opuCD GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 ko:K05846 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 iYO844.BSU33800 Bacteria 1TQ5C@1239,3F51B@33958,4HAVM@91061,COG1174@1,COG1174@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component FFAGCILK_01653 543734.LCABL_00640 3.3e-172 610.9 Lactobacillaceae opuCC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 ko:K05845,ko:K05846 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 iSB619.SA_RS12835 Bacteria 1TQ7D@1239,3F420@33958,4HARV@91061,COG1732@1,COG1732@2 NA|NA|NA M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) FFAGCILK_01654 543734.LCABL_00650 1e-105 389.4 Lactobacillaceae opuCB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0044464,GO:0051179,GO:0051234,GO:0071705,GO:0071944 ko:K05845,ko:K05846 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 iYO844.BSU33720 Bacteria 1TSX8@1239,3F4EM@33958,4HC1D@91061,COG1174@1,COG1174@2 NA|NA|NA E ABC transporter permease FFAGCILK_01655 543734.LCABL_00660 3.4e-217 760.8 Lactobacillaceae opuCA 2.7.7.7 ko:K02342,ko:K05847,ko:K07182 ko00230,ko00240,ko01100,ko02010,ko03030,ko03430,ko03440,map00230,map00240,map01100,map02010,map03030,map03430,map03440 M00209,M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko02000,ko03032,ko03400 3.A.1.12 iSB619.SA_RS12845,iYO844.BSU33730 Bacteria 1TPV8@1239,3F55H@33958,4H9SI@91061,COG1125@1,COG1125@2,COG2905@1,COG2905@2 NA|NA|NA E ABC transporter, ATP-binding protein FFAGCILK_01656 1423734.JCM14202_1230 5.2e-23 114.8 Lactobacillaceae ypbD ko:K07052 ko00000 Bacteria 1W74A@1239,3F750@33958,4IFVR@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity FFAGCILK_01658 543734.LCABL_00670 0.0 1114.4 Lactobacillaceae 3.6.3.3,3.6.3.5 ko:K01534 ko00000,ko01000 3.A.3.6 Bacteria 1TQ07@1239,3F4T3@33958,4H9SP@91061,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase FFAGCILK_01659 543734.LCABL_00680 2.5e-33 147.5 Lactobacillaceae copZ ko:K07213 ko04978,map04978 ko00000,ko00001 Bacteria 1VFJ8@1239,3F830@33958,4HNY2@91061,COG2608@1,COG2608@2 NA|NA|NA P Heavy-metal-associated domain FFAGCILK_01660 543734.LCABL_00700 3.7e-97 360.9 Lactobacillaceae dps ko:K04047 ko00000,ko03036 Bacteria 1VB1X@1239,3F4SN@33958,4HMJG@91061,COG0783@1,COG0783@2 NA|NA|NA P Belongs to the Dps family FFAGCILK_01661 543734.LCABL_00710 1.4e-116 425.6 Lactobacillaceae rcfA 4.1.99.16,4.2.3.22,4.2.3.75 ko:K10187,ko:K21562 ko00909,ko01100,ko01110,map00909,map01100,map01110 R07647,R07648,R08543,R09487 RC01832,RC02159,RC02160,RC02183,RC02425,RC02552 ko00000,ko00001,ko01000,ko03000 Bacteria 1UZT0@1239,3FBKF@33958,4HFR2@91061,COG0664@1,COG0664@2 NA|NA|NA K helix_turn_helix, cAMP Regulatory protein FFAGCILK_01662 543734.LCABL_00720 3.3e-141 507.7 Lactobacillaceae trpA 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPXA@1239,3F50S@33958,4HFQ8@91061,COG0159@1,COG0159@2 NA|NA|NA E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate FFAGCILK_01663 543734.LCABL_00730 1.4e-228 798.5 Lactobacillaceae trpB 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPI3@1239,3F4DT@33958,4H9WC@91061,COG0133@1,COG0133@2 NA|NA|NA E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine FFAGCILK_01664 543734.LCABL_00740 2.3e-102 378.3 Lactobacillaceae trpF GO:0000162,GO:0003674,GO:0003824,GO:0004425,GO:0004640,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48,4.2.1.160,4.2.1.20,5.3.1.24 ko:K01696,ko:K01817,ko:K13498,ko:K22100 ko00260,ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map00790,map01100,map01110,map01130,map01230 M00023,M00840 R00674,R02340,R02722,R03508,R03509,R11072 RC00209,RC00210,RC00700,RC00701,RC00944,RC00945,RC02868,RC03343 ko00000,ko00001,ko00002,ko01000 iJN678.trpF,iPC815.YPO2205,iSBO_1134.SBO_1804,iSDY_1059.SDY_1330 Bacteria 1V6Y0@1239,3F4B6@33958,4HN68@91061,COG0135@1,COG0135@2 NA|NA|NA E Belongs to the TrpF family FFAGCILK_01665 543734.LCABL_00750 2.9e-137 494.6 Lactobacillaceae trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 ko:K01609,ko:K01817,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR94@1239,3F5AK@33958,4HDZQ@91061,COG0134@1,COG0134@2 NA|NA|NA E Belongs to the TrpC family FFAGCILK_01666 543734.LCABL_00760 2.7e-183 647.9 Lactobacillaceae trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP8U@1239,3F50X@33958,4H9KQ@91061,COG0547@1,COG0547@2 NA|NA|NA F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) FFAGCILK_01667 543734.LCABL_00830 1.7e-207 728.4 Lactobacillaceae Bacteria 1U5H7@1239,2C353@1,309Q7@2,3F5XZ@33958,4IF82@91061 NA|NA|NA FFAGCILK_01668 543734.LCABL_00840 2.9e-305 1053.9 Lactobacillaceae norB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 ko:K08170 M00702 ko00000,ko00002,ko01504,ko02000 2.A.1.3.23,2.A.1.3.59 Bacteria 1TPV3@1239,3F5DE@33958,4HCJN@91061,COG0477@1,COG0477@2,COG2211@1,COG2211@2 NA|NA|NA EGP Major Facilitator FFAGCILK_01669 543734.LCABL_00850 3.3e-106 391.0 Lactobacillaceae Bacteria 1V9ST@1239,3F5J7@33958,4HP6S@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family FFAGCILK_01671 543734.LCABL_00860 3e-125 454.5 Lactobacillaceae Bacteria 1U7J0@1239,2BJ44@1,32DD4@2,3F9SG@33958,4IHFT@91061 NA|NA|NA FFAGCILK_01672 543734.LCABL_00870 3.5e-214 750.7 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1VKEJ@1239,3F7SD@33958,4HS6Y@91061,COG1277@1,COG1277@2 NA|NA|NA S ABC-type transport system involved in multi-copper enzyme maturation permease component FFAGCILK_01673 543734.LCABL_00880 4.3e-161 573.9 Lactobacillaceae Bacteria 1U71Z@1239,2AD8Y@1,312XZ@2,3F8VJ@33958,4IGWF@91061 NA|NA|NA FFAGCILK_01674 543734.LCABL_00890 3e-106 391.3 Lactobacillaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1UQMC@1239,3F6CK@33958,4HE32@91061,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities FFAGCILK_01676 1423816.BACQ01000055_gene2116 1.3e-24 119.8 Lactobacillaceae Bacteria 1U79G@1239,2AGH5@1,316PQ@2,3F95I@33958,4IH4B@91061 NA|NA|NA FFAGCILK_01677 543734.LCABL_00900 2e-61 241.5 Lactobacillaceae ko:K07171 ko00000,ko01000,ko02048 Bacteria 1W12R@1239,2DXZ0@1,3478Y@2,3FC0I@33958,4HYFZ@91061 NA|NA|NA S PemK-like, MazF-like toxin of type II toxin-antitoxin system FFAGCILK_01678 1400520.LFAB_14565 3e-17 94.4 Lactobacillaceae Bacteria 1U740@1239,29PVW@1,30AU6@2,3F8XY@33958,4IGYG@91061 NA|NA|NA FFAGCILK_01679 543734.LCABL_00960 6.7e-139 500.0 Lactobacillaceae dapB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0070402,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 iJN678.dapB,iNJ661.Rv2773c,iYO844.BSU22490 Bacteria 1TR9D@1239,3F3MA@33958,4HA5X@91061,COG0289@1,COG0289@2 NA|NA|NA E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate FFAGCILK_01680 543734.LCABL_00970 1.8e-167 595.1 Lactobacillaceae dapA 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCK@1239,3F4UH@33958,4H9K9@91061,COG0329@1,COG0329@2 NA|NA|NA E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) FFAGCILK_01681 543734.LCABL_00980 2.3e-220 771.2 Lactobacillaceae hipO GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.47 ko:K05823,ko:K21613 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TPD7@1239,3F419@33958,4H9SG@91061,COG1473@1,COG1473@2 NA|NA|NA E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate FFAGCILK_01682 543734.LCABL_00990 2.1e-70 272.3 Lactobacillaceae dapD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117,2.3.1.89 ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 M00016,M00525 R04364,R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 iSbBS512_1146.SbBS512_E0158,iYO844.BSU14180 Bacteria 1TQUJ@1239,3F3U0@33958,4H9KY@91061,COG2171@1,COG2171@2 NA|NA|NA E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate FFAGCILK_01683 543734.LCABL_01000 8.1e-257 892.5 Lactobacillaceae lysA 4.1.1.19,4.1.1.20 ko:K01585,ko:K01586 ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map00330,map01100,map01110,map01120,map01130,map01230 M00016,M00133,M00525,M00526,M00527 R00451,R00566 RC00299 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS18870 Bacteria 1TPE9@1239,3F3VJ@33958,4H9XW@91061,COG0019@1,COG0019@2 NA|NA|NA E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine FFAGCILK_01684 543734.LCABL_01010 4e-259 900.2 Lactobacillaceae lysC GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iYO844.BSU03790 Bacteria 1TPQJ@1239,3F48V@33958,4HAEP@91061,COG0527@1,COG0527@2 NA|NA|NA E Belongs to the aspartokinase family FFAGCILK_01685 543734.LCABL_01020 2.5e-186 657.9 Lactobacillaceae dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPMN@1239,3F4F7@33958,4HBH4@91061,COG0253@1,COG0253@2 NA|NA|NA E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan FFAGCILK_01686 543734.LCABL_01030 2.4e-195 688.0 Lactobacillaceae asd 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPC6@1239,3F4S9@33958,4HA9H@91061,COG0136@1,COG0136@2 NA|NA|NA E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate FFAGCILK_01687 543734.LCABL_01040 2.5e-62 244.6 Lactobacillaceae Bacteria 1U75Z@1239,29PM4@1,30AVT@2,3F90S@33958,4IH0M@91061 NA|NA|NA FFAGCILK_01688 543734.LCABL_01050 4.5e-73 280.4 Lactobacillaceae 3.6.1.55 ko:K03574 ko00000,ko01000,ko03400 Bacteria 1VK3S@1239,3F9X5@33958,4IHJ0@91061,COG0494@1,COG0494@2 NA|NA|NA L NUDIX domain FFAGCILK_01689 543734.LCABL_01060 3.1e-148 531.2 Lactobacillaceae Bacteria 1V86F@1239,3F4CV@33958,4HJWZ@91061,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family FFAGCILK_01690 543734.LCABL_01070 2.7e-95 354.8 Lactobacillaceae Bacteria 1TVFA@1239,29XQD@1,30JG1@2,3FAZJ@33958,4I1PS@91061 NA|NA|NA S Phospholipase A2 FFAGCILK_01692 543734.LCABL_01090 0.0 1284.2 Lactobacillaceae yybT Bacteria 1TPGP@1239,3F3TY@33958,4HBVH@91061,COG3887@1,COG3887@2 NA|NA|NA T signaling protein consisting of a modified GGDEF domain and a DHH domain FFAGCILK_01693 543734.LCABL_01100 9e-75 286.2 Lactobacillaceae rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02939 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6QG@1239,3F68P@33958,4HIKJ@91061,COG0359@1,COG0359@2 NA|NA|NA J Binds to the 23S rRNA FFAGCILK_01694 543734.LCABL_01110 2.3e-246 857.8 Lactobacillaceae dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Bacteria 1TPCT@1239,3F4MW@33958,4H9Y8@91061,COG0305@1,COG0305@2 NA|NA|NA L Participates in initiation and elongation during chromosome replication FFAGCILK_01695 543734.LCABL_01120 1.3e-218 765.4 Lactobacillaceae Bacteria 1U598@1239,2CC2J@1,309K5@2,3F58S@33958,4IF0I@91061 NA|NA|NA FFAGCILK_01696 568703.LGG_00125 7e-281 973.0 Lactobacillaceae sacX GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090588 2.7.1.199,2.7.1.208,2.7.1.211 ko:K02755,ko:K02756,ko:K02757,ko:K02790,ko:K02791,ko:K02808,ko:K02809,ko:K02810 ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060 M00266,M00269,M00271 R00811,R02738,R04111 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.3,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9 Bacteria 1TP5X@1239,3F458@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system FFAGCILK_01697 1423732.BALS01000041_gene2564 7.6e-129 466.8 Lactobacillaceae murQ 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 R08555 RC00397,RC00746 ko00000,ko00001,ko01000 Bacteria 1TPSF@1239,3F4T1@33958,4HBWP@91061,COG2103@1,COG2103@2 NA|NA|NA G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate FFAGCILK_01698 568703.LGG_00128 1.9e-118 432.2 Lactobacillaceae Bacteria 1TPIX@1239,3F5WQ@33958,4HBJA@91061,COG1737@1,COG1737@2 NA|NA|NA K Helix-turn-helix domain, rpiR family FFAGCILK_01699 568703.LGG_00129 2.6e-93 348.2 Lactobacillaceae Bacteria 1V9XI@1239,3F77G@33958,4HJ7Q@91061,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator C-terminal region FFAGCILK_01700 568703.LGG_00130 2.9e-112 411.4 Lactobacillaceae ko:K02003,ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQC9@1239,3F3YU@33958,4HB8D@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein FFAGCILK_01701 568703.LGG_00131 0.0 1211.4 Lactobacillaceae ylbB ko:K02004,ko:K06994 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPHU@1239,3F4HF@33958,4HA2C@91061,COG0577@1,COG0577@2,COG1511@1,COG1511@2 NA|NA|NA V ABC transporter permease FFAGCILK_01702 568703.LGG_00132 1.2e-167 595.9 Lactobacillaceae 4.1.1.52 ko:K22213 ko00000,ko01000 Bacteria 1TRAY@1239,3F485@33958,4HFH2@91061,COG2159@1,COG2159@2 NA|NA|NA S Amidohydrolase FFAGCILK_01703 543734.LCABL_01130 2.4e-250 870.9 Lactobacillaceae purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ4C@1239,3F3RQ@33958,4H9YT@91061,COG0104@1,COG0104@2 NA|NA|NA F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP FFAGCILK_01704 543734.LCABL_01140 0.0 1120.1 Lactobacillaceae cadA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.3,3.6.3.5 ko:K01534,ko:K12951,ko:K21887 ko00000,ko01000 3.A.3,3.A.3.6 Bacteria 1TQ07@1239,3F4T3@33958,4H9SP@91061,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase FFAGCILK_01705 543734.LCABL_01150 1.1e-56 225.7 Lactobacillaceae nmtR GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090 ko:K21886,ko:K21903,ko:K22298 ko00000,ko03000 Bacteria 1VA6G@1239,3FB53@33958,4HFYU@91061,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor FFAGCILK_01706 543734.LCABL_01160 0.0 1466.8 Lactobacillaceae 3.6.3.2,3.6.3.6 ko:K01531,ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 3.A.3.3,3.A.3.4 Bacteria 1TPF5@1239,3F55J@33958,4HVA4@91061,COG0474@1,COG0474@2 NA|NA|NA P Cation transporter/ATPase, N-terminus FFAGCILK_01707 543734.LCABL_01170 4.8e-157 560.5 Lactobacillaceae lysR5 Bacteria 1UXFR@1239,3F4XG@33958,4HBNZ@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain FFAGCILK_01708 543734.LCABL_01180 1.5e-200 705.3 Lactobacillaceae Bacteria 1TNYC@1239,3F58D@33958,4HF5V@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins FFAGCILK_01709 543734.LCABL_01190 2.6e-32 144.1 Lactobacillaceae Bacteria 1VF37@1239,2E3AZ@1,32YAF@2,3F8CH@33958,4HP14@91061 NA|NA|NA S Phospholipase_D-nuclease N-terminal FFAGCILK_01710 543734.LCABL_01200 5.4e-167 593.6 Lactobacillaceae yxlF ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQEV@1239,3F612@33958,4HBHF@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter FFAGCILK_01711 543734.LCABL_01210 7.9e-132 476.5 Lactobacillaceae ko:K01992,ko:K19341 ko02010,map02010 M00254,M00762 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.132.2 Bacteria 1UYUR@1239,3F5JZ@33958,4HIS1@91061,COG1277@1,COG1277@2 NA|NA|NA S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component FFAGCILK_01712 543734.LCABL_01220 0.0 1488.8 Lactobacillaceae nrdD GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0017076,GO:0018130,GO:0019001,GO:0019103,GO:0019438,GO:0019637,GO:0019692,GO:0030554,GO:0031250,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032556,GO:0032558,GO:0032559,GO:0032560,GO:0032564,GO:0032567,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0046872,GO:0046914,GO:0051065,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_4713,iPC815.YPO3454 Bacteria 1TR9K@1239,3F435@33958,4HBIY@91061,COG1328@1,COG1328@2 NA|NA|NA F Ribonucleoside-triphosphate reductase FFAGCILK_01713 543734.LCABL_01230 5.2e-120 437.2 Lactobacillaceae Bacteria 1VPN2@1239,2E7NX@1,33B9D@2,3F7ZV@33958,4HS0V@91061 NA|NA|NA FFAGCILK_01714 543734.LCABL_01240 5.2e-102 377.1 Lactobacillaceae Bacteria 1V6QF@1239,3F7M5@33958,4HIIT@91061,COG1476@1,COG1476@2 NA|NA|NA K Bacteriophage CI repressor helix-turn-helix domain FFAGCILK_01715 543734.LCABL_01250 3.5e-260 903.7 Lactobacillaceae Bacteria 1V57P@1239,2DBW0@1,2ZBE0@2,3F5BJ@33958,4HH8K@91061 NA|NA|NA FFAGCILK_01716 543734.LCABL_01260 5.5e-141 506.9 Lactobacillaceae Bacteria 1V45T@1239,3F6PM@33958,4HHSG@91061,COG0639@1,COG0639@2 NA|NA|NA T Calcineurin-like phosphoesterase superfamily domain FFAGCILK_01717 543734.LCABL_01270 1.3e-257 895.2 Bacilli Bacteria 1U53V@1239,4HDF7@91061,COG0277@1,COG0277@2 NA|NA|NA C COG0277 FAD FMN-containing dehydrogenases FFAGCILK_01719 543734.LCABL_01300 3.2e-38 164.1 Bacilli Bacteria 1VM60@1239,2ENBH@1,33FZ4@2,4HREG@91061 NA|NA|NA FFAGCILK_01720 543734.LCABL_01310 1.7e-42 178.3 Lactobacillaceae Bacteria 1VGSH@1239,3F84H@33958,4HQ68@91061,COG3877@1,COG3877@2 NA|NA|NA S Protein of unknown function (DUF2089) FFAGCILK_01721 543734.LCABL_01320 5.3e-181 640.2 Lactobacillaceae Bacteria 1V7AD@1239,3F4Q4@33958,4HJB7@91061,COG0671@1,COG0671@2 NA|NA|NA I PAP2 superfamily FFAGCILK_01722 543734.LCABL_01330 3.9e-209 733.8 Lactobacillaceae mccF Bacteria 1TRBB@1239,3F3NK@33958,4HDUZ@91061,COG1619@1,COG1619@2 NA|NA|NA V LD-carboxypeptidase FFAGCILK_01723 543734.LCABL_01340 1.5e-42 178.3 Lactobacillaceae Bacteria 1U7ZU@1239,29QF0@1,30BEB@2,3FAD7@33958,4IHX8@91061 NA|NA|NA FFAGCILK_01724 543734.LCABL_01350 4e-206 723.8 Lactobacillaceae ddl 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1TP2Y@1239,3F41Z@33958,4H9KB@91061,COG1181@1,COG1181@2 NA|NA|NA F Belongs to the D-alanine--D-alanine ligase family FFAGCILK_01725 543734.LCABL_01360 1.4e-89 335.5 Lactobacillaceae ogt 2.1.1.63 ko:K00567,ko:K10778,ko:K13531 ko00000,ko01000,ko03000,ko03400 Bacteria 1VA03@1239,3F6RF@33958,4HETA@91061,COG0350@1,COG0350@2 NA|NA|NA L Methyltransferase FFAGCILK_01726 543734.LCABL_01370 2.8e-193 681.0 Lactobacillaceae ldhD3 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 R00704 RC00044 ko00000,ko00001,ko01000 Bacteria 1TSZ6@1239,3F4US@33958,4HCIS@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family FFAGCILK_01727 543734.LCABL_01380 2.4e-44 184.5 Firmicutes Bacteria 1W538@1239,298HG@1,2ZKVW@2 NA|NA|NA FFAGCILK_01728 543734.LCABL_01390 3.1e-84 317.8 Lactobacillaceae slyA Bacteria 1W4X8@1239,3F8CB@33958,4I172@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator FFAGCILK_01729 543734.LCABL_01400 7.6e-161 573.2 Lactobacillaceae 1.6.5.5 ko:K00344 ko00000,ko01000 Bacteria 1V2UJ@1239,3F52N@33958,4HG2A@91061,COG0604@1,COG0604@2 NA|NA|NA C alcohol dehydrogenase FFAGCILK_01730 543734.LCABL_01410 1.6e-53 215.3 Lactobacillaceae ypaA ko:K08987 ko00000 Bacteria 1VAVU@1239,3F7NA@33958,4HQHN@91061,COG3759@1,COG3759@2 NA|NA|NA S Protein of unknown function (DUF1304) FFAGCILK_01731 543734.LCABL_01420 5.2e-54 216.9 Lactobacillaceae Bacteria 1VPXU@1239,2EGA1@1,33A1U@2,3F7WK@33958,4HS3Y@91061 NA|NA|NA S Protein of unknown function (DUF1516) FFAGCILK_01732 543734.LCABL_01430 9.1e-254 882.5 Lactobacillaceae pbuO ko:K06901 ko00000,ko02000 2.A.1.40 Bacteria 1TQC6@1239,3F44D@33958,4HANG@91061,COG2252@1,COG2252@2 NA|NA|NA S permease FFAGCILK_01733 568703.LGG_00169 6.3e-46 189.9 Lactobacillaceae ko:K09004 ko00000 Bacteria 1VEYT@1239,3FBBQ@33958,4HQQN@91061,COG1416@1,COG1416@2 NA|NA|NA S DsrE/DsrF-like family FFAGCILK_01735 568703.LGG_00172 3.7e-102 377.9 Lactobacillaceae tauB GO:0003674,GO:0003824,GO:0005215,GO:0005342,GO:0005368,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0008559,GO:0015075,GO:0015238,GO:0015399,GO:0015405,GO:0015411,GO:0015711,GO:0015734,GO:0015849,GO:0015893,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033283,GO:0034220,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042908,GO:0042910,GO:0043492,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0072348,GO:0098656,GO:1901682,GO:1903825 3.6.3.36 ko:K02049,ko:K10831 ko00920,ko02010,map00920,map02010 M00188,M00435 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4 Bacteria 1TRM6@1239,3FC3F@33958,4HBZ6@91061,COG1116@1,COG1116@2 NA|NA|NA P ATPases associated with a variety of cellular activities FFAGCILK_01736 568703.LGG_00173 1e-118 433.3 Bacilli tauA GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009970,GO:0009987,GO:0009991,GO:0015711,GO:0015734,GO:0015849,GO:0030288,GO:0030313,GO:0031667,GO:0031668,GO:0031669,GO:0031975,GO:0033554,GO:0042594,GO:0042597,GO:0042908,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0071496,GO:0071702,GO:0071705,GO:0072348 ko:K15551 ko00920,ko02010,map00920,map02010 M00435 ko00000,ko00001,ko00002,ko02000 3.A.1.17.1,3.A.1.17.4 iECOK1_1307.ECOK1_0347,iECS88_1305.ECS88_0362,iUMN146_1321.UM146_15535 Bacteria 1TSJU@1239,4HFCZ@91061,COG4521@1,COG4521@2 NA|NA|NA P NMT1-like family FFAGCILK_01737 568703.LGG_00174 6e-103 380.6 Lactobacillaceae tauC ko:K15552 ko00920,ko02010,map00920,map02010 M00435 ko00000,ko00001,ko00002,ko02000 3.A.1.17.1,3.A.1.17.4 Bacteria 1U217@1239,3FBIE@33958,4HCS9@91061,COG0600@1,COG0600@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component FFAGCILK_01738 568703.LGG_00175 3.6e-278 963.8 Lactobacillaceae naoX Bacteria 1TPWW@1239,3FBSF@33958,4HA11@91061,COG0446@1,COG0446@2,COG0607@1,COG0607@2 NA|NA|NA P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain FFAGCILK_01739 568703.LGG_00176 1.1e-216 759.2 Lactobacillaceae ko:K07112 ko00000 Bacteria 1TSNG@1239,3F7RB@33958,4HCH9@91061,COG2391@1,COG2391@2 NA|NA|NA S Sulphur transport FFAGCILK_01740 568703.LGG_00177 1.8e-98 365.9 Lactobacillaceae Bacteria 1U35Y@1239,3FBI9@33958,4HCXK@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain FFAGCILK_01742 568703.LGG_00178 1.7e-179 635.2 Lactobacillaceae mhqA 3.4.21.26 ko:K01322,ko:K15975 ko04614,map04614 ko00000,ko00001,ko01000,ko01002 Bacteria 1TP7I@1239,3F4PB@33958,4H9ND@91061,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FFAGCILK_01743 568703.LGG_00179 2.2e-29 134.8 Lactobacillaceae Bacteria 1U7RE@1239,29Q9W@1,30B8Z@2,3FA2D@33958,4IHNS@91061 NA|NA|NA FFAGCILK_01744 543734.LCABL_01470 7.6e-103 379.8 Lactobacillaceae yoaA 2.3.1.128 ko:K03790 ko00000,ko01000,ko03009 Bacteria 1VCN3@1239,3F7GP@33958,4HKNF@91061,COG1670@1,COG1670@2 NA|NA|NA J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins FFAGCILK_01745 543734.LCABL_01490 0.0 1148.7 Lactobacillaceae Bacteria 1VXAH@1239,2F70X@1,33ZGK@2,3F9HI@33958,4HXTD@91061 NA|NA|NA FFAGCILK_01747 543734.LCABL_01520 3.7e-121 441.0 Lactobacillaceae Bacteria 1U57C@1239,29WH0@1,30I33@2,3F511@33958,4IEYT@91061 NA|NA|NA S WxL domain surface cell wall-binding FFAGCILK_01748 543734.LCABL_01530 4.7e-121 440.7 Lactobacillaceae Bacteria 1V9D9@1239,3F7MH@33958,4HJPY@91061,COG4886@1,COG4886@2 NA|NA|NA S WxL domain surface cell wall-binding FFAGCILK_01749 543734.LCABL_01540 3.1e-182 644.4 Lactobacillaceae ynjC Bacteria 1VCXS@1239,3F5HA@33958,4HKJG@91061,COG4072@1,COG4072@2 NA|NA|NA S Cell surface protein FFAGCILK_01751 543734.LCABL_01560 1.9e-267 927.9 Lactobacillaceae ko:K02538 ko00000,ko03000 Bacteria 1VBUE@1239,3FBAD@33958,4HN8V@91061,COG3711@1,COG3711@2 NA|NA|NA L Mga helix-turn-helix domain FFAGCILK_01752 543734.LCABL_01570 1.2e-172 612.5 Lactobacillaceae yhaI Bacteria 1VP5A@1239,3F6XM@33958,4IFSK@91061,COG3152@1,COG3152@2 NA|NA|NA S Protein of unknown function (DUF805) FFAGCILK_01753 543734.LCABL_01580 1.2e-57 228.8 Lactobacillaceae Bacteria 1U6JW@1239,2C1B3@1,302T3@2,3F821@33958,4IGCF@91061 NA|NA|NA FFAGCILK_01754 543734.LCABL_01590 1.1e-253 882.1 Lactobacillaceae rarA ko:K07478 ko00000 Bacteria 1TPVV@1239,3F3NB@33958,4HAIS@91061,COG2256@1,COG2256@2 NA|NA|NA L recombination factor protein RarA FFAGCILK_01755 543734.LCABL_01600 7.5e-222 776.2 Lactobacillaceae ackA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0409 Bacteria 1TQ22@1239,3F48Z@33958,4HA7K@91061,COG0282@1,COG0282@2 NA|NA|NA F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction FFAGCILK_01756 543734.LCABL_01610 3.3e-160 570.9 Lactobacillaceae pphA 3.1.3.16 ko:K01090,ko:K07313 ko00000,ko01000 Bacteria 1V1HN@1239,3FCCD@33958,4HHQ3@91061,COG0639@1,COG0639@2 NA|NA|NA T Calcineurin-like phosphoesterase superfamily domain FFAGCILK_01757 543734.LCABL_01620 4.9e-139 500.4 Lactobacillaceae magIII ko:K07457 ko00000 Bacteria 1V4SG@1239,3F62T@33958,4HI5U@91061,COG2231@1,COG2231@2 NA|NA|NA L Base excision DNA repair protein, HhH-GPD family FFAGCILK_01758 543734.LCABL_01630 9.8e-46 189.1 Lactobacillaceae Bacteria 1VC4R@1239,3F7GK@33958,4HSQA@91061,COG0011@1,COG0011@2 NA|NA|NA S Thiamine-binding protein FFAGCILK_01759 543734.LCABL_01640 2.8e-205 722.2 Lactobacillaceae yhgE ko:K01421 ko00000 Bacteria 1TQ15@1239,3F3Y3@33958,4H9T9@91061,COG1511@1,COG1511@2 NA|NA|NA V domain protein FFAGCILK_01760 543734.LCABL_01650 2e-100 371.7 Lactobacillaceae yobS GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 Bacteria 1V1DM@1239,3F5CS@33958,4HG0Y@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family FFAGCILK_01761 543734.LCABL_01660 3.2e-251 874.0 Lactobacillaceae bmr3 Bacteria 1VSW8@1239,3F4AW@33958,4HUQC@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily FFAGCILK_01763 543734.LCABL_01680 0.0 1655.2 Lactobacillaceae xfp 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 Bacteria 1TR23@1239,3F3TZ@33958,4HC2J@91061,COG3957@1,COG3957@2 NA|NA|NA G Phosphoketolase FFAGCILK_01764 543734.LCABL_01690 4.7e-299 1033.1 Lactobacillaceae oppA ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TNYQ@1239,3F3JE@33958,4HAMK@91061,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter, substratebinding protein FFAGCILK_01765 1423816.BACQ01000036_gene1474 9e-13 80.1 Lactobacillaceae Bacteria 1U7R9@1239,2BKSQ@1,32F8U@2,3FA21@33958,4IHNM@91061 NA|NA|NA FFAGCILK_01766 1423816.BACQ01000030_gene1065 2.8e-76 292.0 Lactobacillaceae Bacteria 1TZIV@1239,2BFQS@1,329JG@2,3F8FT@33958,4IGKR@91061 NA|NA|NA FFAGCILK_01767 568703.LGG_00203 1.6e-41 176.4 Lactobacillaceae Bacteria 1U7P7@1239,2AHJ7@1,317WU@2,3F9Z1@33958,4IHKH@91061 NA|NA|NA FFAGCILK_01768 1423732.BALS01000077_gene2127 6e-67 260.8 Lactobacillaceae Bacteria 1U7B5@1239,29Q10@1,30AZH@2,3F994@33958,4IH65@91061 NA|NA|NA FFAGCILK_01769 1423816.BACQ01000030_gene1062 8.1e-88 330.1 Lactobacillaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V1P4@1239,3FC3S@33958,4HDRD@91061,COG1131@1,COG1131@2 NA|NA|NA V ATPases associated with a variety of cellular activities FFAGCILK_01770 1423816.BACQ01000030_gene1061 3.6e-42 177.9 Lactobacillaceae Bacteria 1U7QJ@1239,29Q9A@1,30B8E@2,3FA0T@33958,4IHMW@91061 NA|NA|NA FFAGCILK_01771 543734.LCABL_01720 1.1e-78 299.3 Bacilli Bacteria 1W1ZW@1239,2BFZ1@1,329UX@2,4I0E0@91061 NA|NA|NA S NUDIX domain FFAGCILK_01772 543734.LCABL_01730 9.4e-214 749.2 Lactobacillaceae Bacteria 1UPQ9@1239,3FC0K@33958,4IV8X@91061,COG1537@1,COG1537@2 NA|NA|NA S nuclear-transcribed mRNA catabolic process, no-go decay FFAGCILK_01773 1423816.BACQ01000030_gene1058 3.9e-226 790.8 Lactobacillaceae ko:K06147,ko:K06148 ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TSRV@1239,3F6VM@33958,4HCIZ@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region FFAGCILK_01774 568703.LGG_00210 1.8e-111 409.1 Lactobacillaceae gadR Bacteria 1UZI0@1239,3F8VZ@33958,4HC2C@91061,COG1396@1,COG1396@2 NA|NA|NA K Transcriptional activator, Rgg GadR MutR family FFAGCILK_01775 543734.LCABL_01740 0.0 1238.0 Lactobacillaceae fnq20 1.13.12.16 ko:K00459 ko00910,map00910 R00025 RC02541,RC02759 ko00000,ko00001,ko01000 Bacteria 1UZ38@1239,3F4ZH@33958,4HDXC@91061,COG4529@1,COG4529@2 NA|NA|NA S FAD-NAD(P)-binding FFAGCILK_01776 543734.LCABL_01750 3.8e-262 910.2 Lactobacillaceae nox 1.6.3.4 ko:K17869 ko00000,ko01000 Bacteria 1TPWW@1239,3F449@33958,4H9U7@91061,COG0446@1,COG0446@2 NA|NA|NA C NADH oxidase FFAGCILK_01777 543734.LCABL_01760 1.1e-115 422.5 Lactobacillaceae Bacteria 1U55V@1239,29DQI@1,300NC@2,3F4UQ@33958,4IEX6@91061 NA|NA|NA FFAGCILK_01778 543734.LCABL_01770 5.6e-218 763.5 Lactobacillaceae ko:K06872 ko00000 Bacteria 1VHE2@1239,3F75Q@33958,4HJHN@91061,COG1512@1,COG1512@2 NA|NA|NA S TPM domain FFAGCILK_01779 543734.LCABL_01780 1.8e-124 452.2 Lactobacillaceae yxaA ko:K07090 ko00000 Bacteria 1TPMA@1239,3FCAW@33958,4HCYJ@91061,COG0730@1,COG0730@2 NA|NA|NA S Sulfite exporter TauE/SafE FFAGCILK_01780 543734.LCABL_01790 1e-55 222.6 Lactobacillaceae ywjH Bacteria 1VAPQ@1239,3FBP6@33958,4IRG9@91061,COG4272@1,COG4272@2 NA|NA|NA S Protein of unknown function (DUF1634) FFAGCILK_01782 543734.LCABL_01810 6.5e-90 336.7 Lactobacillaceae Bacteria 1U898@1239,29QKG@1,30BK4@2,3FAQ9@33958,4II73@91061 NA|NA|NA FFAGCILK_01783 568703.LGG_00220 2.8e-48 197.6 Lactobacillaceae Bacteria 1U7P0@1239,29Q8B@1,30B7C@2,3F9YT@33958,4IHK9@91061 NA|NA|NA FFAGCILK_01784 543734.LCABL_01830 1.6e-82 312.0 Lactobacillaceae fld ko:K03839 ko00000 Bacteria 1U7EW@1239,3F9HX@33958,4IHAT@91061,COG0716@1,COG0716@2 NA|NA|NA C Flavodoxin FFAGCILK_01785 1423816.BACQ01000030_gene1046 1.2e-36 158.7 Lactobacillaceae Bacteria 1USWD@1239,2930D@1,3270J@2,3F7S4@33958,4IG6X@91061 NA|NA|NA FFAGCILK_01786 543734.LCABL_01850 1.1e-26 125.2 Lactobacillaceae Bacteria 1U8D5@1239,29QNT@1,30BNF@2,3FAUS@33958,4IIB4@91061 NA|NA|NA FFAGCILK_01787 543734.LCABL_01860 1.9e-170 605.1 Lactobacillaceae 1.1.1.26 ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko01000 Bacteria 1TPCX@1239,3F4Z6@33958,4HASY@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family FFAGCILK_01788 543734.LCABL_01870 1.4e-71 275.4 Lactobacillaceae pdxH ko:K07006 ko00000 Bacteria 1V4U5@1239,3FBB6@33958,4HX4S@91061,COG3576@1,COG3576@2 NA|NA|NA S Pyridoxamine 5'-phosphate oxidase FFAGCILK_01789 543734.LCABL_01880 3.5e-39 167.2 Lactobacillaceae Bacteria 1VENK@1239,3F7EK@33958,4HNKV@91061,COG2261@1,COG2261@2 NA|NA|NA S Transglycosylase associated protein FFAGCILK_01790 543734.LCABL_01890 5.3e-82 310.5 Lactobacillaceae Bacteria 1VN34@1239,3F8AH@33958,4HRAM@91061,COG1302@1,COG1302@2 NA|NA|NA S Protein conserved in bacteria FFAGCILK_01791 568703.LGG_00229 2.8e-25 120.6 Lactobacillaceae Bacteria 1U7VV@1239,29QCQ@1,30BBZ@2,3FA8J@33958,4IHT8@91061 NA|NA|NA FFAGCILK_01792 543734.LCABL_01910 7.4e-68 263.1 Lactobacillaceae asp23 Bacteria 1VCNX@1239,3FB58@33958,4HKR6@91061,COG1302@1,COG1302@2 NA|NA|NA S Asp23 family, cell envelope-related function FFAGCILK_01793 543734.LCABL_01920 6.3e-62 243.4 Lactobacillaceae asp2 Bacteria 1VJRA@1239,3F692@33958,4HXJN@91061,COG1302@1,COG1302@2 NA|NA|NA S Asp23 family, cell envelope-related function FFAGCILK_01794 543734.LCABL_01930 1.1e-113 416.0 Lactobacillaceae Bacteria 1TT00@1239,3F538@33958,4HE38@91061,COG3819@1,COG3819@2 NA|NA|NA S Protein of unknown function (DUF969) FFAGCILK_01795 543734.LCABL_01940 4.8e-152 543.9 Lactobacillaceae Bacteria 1TQ17@1239,3F5QJ@33958,4HAJT@91061,COG3817@1,COG3817@2 NA|NA|NA S Protein of unknown function (DUF979) FFAGCILK_01796 543734.LCABL_01950 5e-119 433.7 Lactobacillaceae pcp GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.19.3 ko:K01304 ko00000,ko01000,ko01002 Bacteria 1TRRX@1239,3F46I@33958,4HCIJ@91061,COG2039@1,COG2039@2 NA|NA|NA O Removes 5-oxoproline from various penultimate amino acid residues except L-proline FFAGCILK_01797 543734.LCABL_01960 6.5e-108 396.7 Lactobacillaceae 1.5.1.40 ko:K06988 ko00000,ko01000 Bacteria 1VW6H@1239,3F6QU@33958,4HWI6@91061,COG2085@1,COG2085@2 NA|NA|NA S NADP oxidoreductase coenzyme F420-dependent FFAGCILK_01798 543734.LCABL_01970 1.1e-126 459.1 Lactobacillaceae cobQ ko:K07009 ko00000 Bacteria 1U7I9@1239,3F4CH@33958,4HD1P@91061,COG3442@1,COG3442@2 NA|NA|NA S glutamine amidotransferase FFAGCILK_01799 543734.LCABL_01980 1.3e-66 258.8 Lactobacillaceae Bacteria 1U6EK@1239,29PCH@1,30AAR@2,3F7R0@33958,4IG6D@91061 NA|NA|NA FFAGCILK_01800 543734.LCABL_01990 3.2e-130 471.1 Lactobacillaceae rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 ko00000,ko01000,ko03009,ko03036 Bacteria 1TPBT@1239,3F3ZX@33958,4HAAZ@91061,COG0357@1,COG0357@2 NA|NA|NA J Specifically methylates the N7 position of a guanine in 16S rRNA FFAGCILK_01801 543734.LCABL_02000 1.5e-144 518.8 Lactobacillaceae noc ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 1TP0I@1239,3F4RU@33958,4HAC6@91061,COG1475@1,COG1475@2 NA|NA|NA K Belongs to the ParB family FFAGCILK_01802 543734.LCABL_02010 9.7e-138 496.1 Lactobacillaceae soj ko:K03496 ko00000,ko03036,ko04812 Bacteria 1TP8S@1239,3F4AE@33958,4HAYM@91061,COG1192@1,COG1192@2 NA|NA|NA D Sporulation initiation inhibitor FFAGCILK_01803 543734.LCABL_02020 5.2e-156 557.0 Lactobacillaceae spo0J GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 1TQ2B@1239,3F47R@33958,4H9TB@91061,COG1475@1,COG1475@2 NA|NA|NA K Belongs to the ParB family FFAGCILK_01804 543734.LCABL_02030 1.8e-29 134.4 Lactobacillaceae yyzM Bacteria 1VEQ7@1239,3F823@33958,4HNHU@91061,COG4481@1,COG4481@2 NA|NA|NA S Bacterial protein of unknown function (DUF951) FFAGCILK_01805 543734.LCABL_02040 1.3e-185 655.6 Lactobacillaceae ychF GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772 ko:K06942 ko00000,ko03009 Bacteria 1TPRK@1239,3F3TK@33958,4H9SQ@91061,COG0012@1,COG0012@2 NA|NA|NA J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner FFAGCILK_01806 543734.LCABL_02050 2.1e-106 392.1 Lactobacillaceae XK27_01040 Bacteria 1VF5N@1239,3F4JS@33958,4HH7B@91061,COG4858@1,COG4858@2 NA|NA|NA S Protein of unknown function (DUF1129) FFAGCILK_01807 543734.LCABL_02060 2.5e-275 954.1 Lactobacillaceae guaB GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027 Bacteria 1TNZ1@1239,3F3XN@33958,4H9V3@91061,COG0516@1,COG0516@2,COG0517@1,COG0517@2 NA|NA|NA F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides FFAGCILK_01808 543734.LCABL_02070 1.6e-120 438.7 Lactobacillaceae Bacteria 1VW0F@1239,2F4SR@1,33XFD@2,3F6TR@33958,4HWCG@91061 NA|NA|NA FFAGCILK_01809 543734.LCABL_02080 1.9e-121 441.8 Lactobacillaceae Bacteria 1TP9M@1239,3F3Y0@33958,4HB3T@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator FFAGCILK_01810 543734.LCABL_02090 3.9e-218 763.8 Lactobacillaceae hpk31 2.7.13.3 ko:K07636 ko02020,map02020 M00434 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TPB6@1239,3F479@33958,4HARU@91061,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase FFAGCILK_01811 543734.LCABL_02100 1.8e-237 828.2 Lactobacillaceae dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 1TQN0@1239,3F43S@33958,4HBD4@91061,COG1686@1,COG1686@2 NA|NA|NA M Belongs to the peptidase S11 family FFAGCILK_01812 543734.LCABL_02110 1.6e-79 302.0 Lactobacillaceae greA ko:K03624,ko:K04760 ko00000,ko03021 Bacteria 1V1G3@1239,3F6ZK@33958,4HW8H@91061,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides FFAGCILK_01813 543734.LCABL_02120 4.3e-294 1016.5 Lactobacillaceae murE 6.3.2.13,6.3.2.7 ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 R02786,R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 Bacteria 1TPQE@1239,3F3UE@33958,4H9T1@91061,COG0769@1,COG0769@2 NA|NA|NA M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan FFAGCILK_01814 543734.LCABL_02130 5.4e-141 506.9 Lactobacillaceae racD 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 R00491 RC00302 ko00000,ko00001,ko01000 Bacteria 1V34N@1239,3F3XZ@33958,4HG8W@91061,COG1794@1,COG1794@2 NA|NA|NA G Belongs to the aspartate glutamate racemases family FFAGCILK_01815 543734.LCABL_02140 3.3e-163 580.9 Lactobacillaceae yvgN Bacteria 1TPM1@1239,3F3PW@33958,4HARE@91061,COG0656@1,COG0656@2 NA|NA|NA C Aldo keto reductase FFAGCILK_01816 543734.LCABL_02150 2.5e-144 518.1 Bacilli iolR ko:K06608 ko00000,ko03000 Bacteria 1TTGR@1239,4HEVD@91061,COG1349@1,COG1349@2 NA|NA|NA K COG1349 Transcriptional regulators of sugar metabolism FFAGCILK_01817 543734.LCABL_02160 2.7e-258 897.5 Lactobacillaceae iolT ko:K06609 ko00000,ko02000 2.A.1.1.26 Bacteria 1TREV@1239,3F3ZS@33958,4HAN1@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily FFAGCILK_01818 543734.LCABL_02170 1.6e-277 961.4 Lactobacillaceae iolA 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP4S@1239,3F47F@33958,4H9MF@91061,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family FFAGCILK_01819 543734.LCABL_02180 1.6e-154 552.0 Lactobacillaceae iolB 5.3.1.30 ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 R08503 RC00541 ko00000,ko00001,ko01000 Bacteria 1TR6M@1239,3F4TI@33958,4HCDY@91061,COG3718@1,COG3718@2 NA|NA|NA G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate) FFAGCILK_01820 543734.LCABL_02190 1.7e-179 635.2 Lactobacillaceae iolC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009987,GO:0016042,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044262,GO:0044424,GO:0044464,GO:0046434,GO:0046835,GO:0071704,GO:1901575 2.7.1.92 ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 R05661 RC00002,RC00017 ko00000,ko00001,ko01000 iYO844.BSU39740 Bacteria 1TPGM@1239,3FC23@33958,4HB78@91061,COG0524@1,COG0524@2 NA|NA|NA H Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) FFAGCILK_01821 543734.LCABL_02200 0.0 1270.4 Lactobacillaceae iolD 3.7.1.22 ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 R08603 RC02331 ko00000,ko00001,ko01000 Bacteria 1UI18@1239,3F9EH@33958,4HCPP@91061,COG3962@1,COG3962@2 NA|NA|NA E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) FFAGCILK_01822 543734.LCABL_02210 6.4e-193 679.9 Lactobacillaceae iolG 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 R01183,R09951 RC00182 ko00000,ko00001,ko01000 Bacteria 1U4A4@1239,3F94F@33958,4HBTG@91061,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold FFAGCILK_01823 543734.LCABL_02220 1.3e-193 682.2 Lactobacillaceae iolG2 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 R01183,R09951 RC00182 ko00000,ko00001,ko01000 Bacteria 1TQJX@1239,3F5FQ@33958,4HAJ8@91061,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, C-terminal alpha/beta domain FFAGCILK_01824 543734.LCABL_02230 2.8e-173 614.4 Lactobacillaceae iolE 4.2.1.44 ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 R02782,R05659 RC00782,RC01448 ko00000,ko00001,ko01000 Bacteria 1TPZ2@1239,3F5FP@33958,4HCIM@91061,COG1082@1,COG1082@2 NA|NA|NA G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) FFAGCILK_01825 543734.LCABL_02240 4.7e-157 560.5 Lactobacillaceae iolJ 4.1.2.13,4.1.2.29 ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568,R05378 RC00438,RC00439,RC00603,RC00604,RC00721 ko00000,ko00001,ko00002,ko01000 iYO844.BSU39670 Bacteria 1TQ01@1239,3F9NW@33958,4H9ZU@91061,COG0191@1,COG0191@2 NA|NA|NA G Fructose-bisphosphate aldolase class-II FFAGCILK_01826 543734.LCABL_02250 2.3e-66 258.1 Lactobacillaceae iolK Bacteria 1V3SS@1239,3F6UD@33958,4HI9G@91061,COG1942@1,COG1942@2 NA|NA|NA S Tautomerase enzyme FFAGCILK_01827 543734.LCABL_02260 2.5e-123 448.4 Lactobacillaceae gntR Bacteria 1TR0N@1239,3F42G@33958,4HB9E@91061,COG1737@1,COG1737@2 NA|NA|NA K rpiR family FFAGCILK_01828 543734.LCABL_02270 2.5e-169 601.3 Lactobacillaceae gnd 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHN4@1239,3F4X7@33958,4IS44@91061,COG1023@1,COG1023@2 NA|NA|NA G Dehydrogenase FFAGCILK_01829 543734.LCABL_02280 1.9e-305 1054.3 Lactobacillaceae gntK 2.7.1.12,2.7.1.17 ko:K00851,ko:K00854 ko00030,ko00040,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map01100,map01110,map01120,map01130,map01200 M00014 R01639,R01737 RC00002,RC00017,RC00538 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ1I@1239,3F4R2@33958,4H9W6@91061,COG1070@1,COG1070@2 NA|NA|NA G Belongs to the FGGY kinase family FFAGCILK_01830 543734.LCABL_02290 8.8e-211 739.6 Lactobacillaceae gntP ko:K03299,ko:K06155 ko00000,ko02000 2.A.8,2.A.8.1.4 Bacteria 1TQ14@1239,3F3V0@33958,4HB0Y@91061,COG2610@1,COG2610@2 NA|NA|NA EG Gluconate FFAGCILK_01831 543734.LCABL_02390 7.6e-58 229.6 Lactobacillaceae Bacteria 1VZWZ@1239,2CICD@1,3462T@2,3F6T8@33958,4HY4B@91061 NA|NA|NA FFAGCILK_01832 543734.LCABL_02400 2.2e-128 464.9 Lactobacillaceae fhuC 3.6.3.35 ko:K02074,ko:K09817,ko:K19973 ko02010,map02010 M00242,M00244,M00792 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.15,3.A.1.15.3,3.A.1.15.5 Bacteria 1TQ68@1239,3F49M@33958,4HAZI@91061,COG1121@1,COG1121@2 NA|NA|NA P ABC transporter FFAGCILK_01833 543734.LCABL_02410 4.4e-133 480.7 Lactobacillaceae znuB ko:K02075,ko:K09816 ko02010,map02010 M00242,M00244 ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 Bacteria 1V0SX@1239,3F4BC@33958,4HE09@91061,COG1108@1,COG1108@2 NA|NA|NA U ABC 3 transport family FFAGCILK_01834 543734.LCABL_02420 1.8e-161 575.1 Lactobacillaceae Bacteria 1UZK9@1239,3F5JR@33958,4HG1F@91061,COG0639@1,COG0639@2 NA|NA|NA T Calcineurin-like phosphoesterase superfamily domain FFAGCILK_01835 543734.LCABL_02430 4.2e-161 573.9 Lactobacillaceae glxR 1.1.1.31,1.1.1.60 ko:K00020,ko:K00042 ko00280,ko00630,ko01100,map00280,map00630,map01100 R01745,R01747,R05066 RC00099 ko00000,ko00001,ko01000 iJN678.mmsB Bacteria 1TR4F@1239,3F3XC@33958,4H9MA@91061,COG2084@1,COG2084@2 NA|NA|NA I Dehydrogenase FFAGCILK_01836 543734.LCABL_02440 0.0 1197.2 Lactobacillaceae pepF GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 ko:K08602 ko00000,ko01000,ko01002 Bacteria 1TP4P@1239,3F4E5@33958,4HA7X@91061,COG1164@1,COG1164@2 NA|NA|NA E oligoendopeptidase F FFAGCILK_01837 543734.LCABL_02460 1.6e-189 668.7 Lactobacillaceae brpA Bacteria 1TR1B@1239,3F3MQ@33958,4HA09@91061,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-like function transcriptional attenuator common domain protein FFAGCILK_01838 543734.LCABL_02470 4.9e-249 866.7 Lactobacillaceae brnQ GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903785,GO:1903825,GO:1905039 ko:K03311 ko00000 2.A.26 Bacteria 1TQIS@1239,3F3KC@33958,4HAKA@91061,COG1114@1,COG1114@2 NA|NA|NA U Component of the transport system for branched-chain amino acids FFAGCILK_01839 543734.LCABL_02480 7e-71 273.9 Lactobacillaceae ko:K03642,ko:K07184 ko00000 Bacteria 1VB6H@1239,3F7SK@33958,4I1GZ@91061,COG3103@1,COG3103@2 NA|NA|NA T Sh3 type 3 domain protein FFAGCILK_01840 543734.LCABL_02490 1.1e-133 482.6 Lactobacillaceae glcR ko:K02444,ko:K22103 ko00000,ko03000 Bacteria 1V1VH@1239,3FC5T@33958,4HHQ0@91061,COG1349@1,COG1349@2 NA|NA|NA K DeoR C terminal sensor domain FFAGCILK_01841 543734.LCABL_02500 2e-146 525.0 Lactobacillaceae Bacteria 1V0TF@1239,3FBRX@33958,4HVF8@91061,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase like family 2 FFAGCILK_01842 543734.LCABL_02510 3.3e-135 487.6 Lactobacillaceae XK27_06755 Bacteria 1U7F2@1239,3F9IA@33958,4IHB0@91061,COG5523@1,COG5523@2 NA|NA|NA S Protein of unknown function (DUF975) FFAGCILK_01843 1423732.BALS01000075_gene2102 1.4e-40 172.2 Lactobacillaceae Bacteria 1U71D@1239,29PTZ@1,30AS5@2,3F8UT@33958,4IGVU@91061 NA|NA|NA FFAGCILK_01844 543734.LCABL_02540 2.4e-107 394.8 Lactobacillaceae lepB 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1V7H9@1239,3F4SM@33958,4HIQ4@91061,COG0681@1,COG0681@2 NA|NA|NA U Belongs to the peptidase S26 family FFAGCILK_01845 543734.LCABL_02550 1.1e-172 612.5 Lactobacillaceae draG Bacteria 1TQXG@1239,3F509@33958,4HE5F@91061,COG1397@1,COG1397@2 NA|NA|NA O ADP-ribosylglycohydrolase FFAGCILK_01846 543734.LCABL_02560 3.6e-293 1013.4 Lactobacillaceae ko:K06158 ko00000,ko03012 Bacteria 1TPAX@1239,3FC7X@33958,4HC58@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter FFAGCILK_01847 543734.LCABL_02570 1.9e-135 488.4 Lactobacillaceae Bacteria 1VDQJ@1239,3F8EP@33958,4IT3M@91061,COG0500@1,COG0500@2 NA|NA|NA Q Methyltransferase domain FFAGCILK_01848 1423816.BACQ01000026_gene919 6.6e-71 273.9 Lactobacillaceae Bacteria 1U7D8@1239,29Q2N@1,30B1A@2,3F9EU@33958,4IH94@91061 NA|NA|NA FFAGCILK_01849 543734.LCABL_09430 5.6e-209 733.4 Lactobacillaceae metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCV@1239,3F3T0@33958,4HB33@91061,COG0192@1,COG0192@2 NA|NA|NA H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme FFAGCILK_01850 543734.LCABL_09440 4e-265 920.2 Lactobacillaceae emrY Bacteria 1VSW8@1239,3F4AW@33958,4HUQC@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily FFAGCILK_01851 543734.LCABL_09450 8.7e-81 306.2 Lactobacillaceae merR ko:K21089,ko:K21972,ko:K22491 ko02026,map02026 ko00000,ko00001,ko03000 Bacteria 1UD22@1239,3F8M4@33958,4IFKE@91061,COG0789@1,COG0789@2 NA|NA|NA K MerR HTH family regulatory protein FFAGCILK_01852 543734.LCABL_09460 3.1e-265 920.6 Lactobacillaceae lmrB Bacteria 1TPRN@1239,3F4A2@33958,4H9VV@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily FFAGCILK_01853 543734.LCABL_09470 5.2e-109 400.6 Lactobacillaceae Bacteria 1VDDQ@1239,2C9UQ@1,32RPZ@2,3F5X9@33958,4HNJB@91061 NA|NA|NA S Domain of unknown function (DUF4811) FFAGCILK_01854 543734.LCABL_09480 2.4e-119 434.9 Lactobacillaceae 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 1VF2U@1239,3F5CM@33958,4HNXR@91061,COG0671@1,COG0671@2 NA|NA|NA I Acid phosphatase homologues FFAGCILK_01856 543734.LCABL_09490 0.0 1686.4 Lactobacillaceae leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TP0Y@1239,3F46M@33958,4HAG1@91061,COG0495@1,COG0495@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family FFAGCILK_01857 543734.LCABL_09500 2.2e-280 971.1 Lactobacillaceae ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03328,ko:K06409 ko00000,ko02000 2.A.66.2,2.A.66.2.14 Bacteria 1TNYX@1239,3F404@33958,4H9RY@91061,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein FFAGCILK_01858 543734.LCABL_09510 7.6e-129 466.5 Lactobacillaceae rsuA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 ko:K06178,ko:K06183 ko00000,ko01000,ko03009 Bacteria 1TQZ2@1239,3F41G@33958,4H9VU@91061,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family FFAGCILK_01859 568703.LGG_00853 1.4e-33 148.3 Lactobacillaceae yhcC ko:K07069 ko00000 Bacteria 1VEIV@1239,3FAC9@33958,4HPKA@91061,COG3478@1,COG3478@2 NA|NA|NA S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) FFAGCILK_01860 543734.LCABL_09520 4.8e-143 513.8 Lactobacillaceae nnrD 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 ko00000,ko01000 Bacteria 1TNZE@1239,3F480@33958,4HBZC@91061,COG0063@1,COG0063@2 NA|NA|NA H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration FFAGCILK_01861 543734.LCABL_09530 4.3e-94 350.5 Lactobacillaceae FNV0100 Bacteria 1VDM3@1239,3F6RN@33958,4HMI0@91061,COG1051@1,COG1051@2 NA|NA|NA F NUDIX domain FFAGCILK_01863 543734.LCABL_10040 1.1e-289 1001.9 Lactobacillaceae tagE2 2.4.1.52 ko:K00712 ko00000,ko01000,ko01003 GT4 Bacteria 1V1TS@1239,3FC16@33958,4HG8T@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 FFAGCILK_01864 543734.LCABL_10050 1.2e-304 1051.6 Lactobacillaceae tagE3 2.4.1.52 ko:K00712 ko00000,ko01000,ko01003 GT4 Bacteria 1UZU7@1239,3FC17@33958,4H9N9@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 FFAGCILK_01865 543734.LCABL_10060 3.7e-87 327.4 Lactobacillaceae btuE 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 Bacteria 1V3M3@1239,3F6A9@33958,4HH5Q@91061,COG0386@1,COG0386@2 NA|NA|NA O Belongs to the glutathione peroxidase family FFAGCILK_01868 543734.LCABL_10070 3.9e-234 817.0 Lactobacillaceae malY 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 Bacteria 1TP5G@1239,3F4JX@33958,4H9PE@91061,COG1168@1,COG1168@2 NA|NA|NA E Aminotransferase, class I FFAGCILK_01869 543734.LCABL_10090 4.3e-258 896.7 Lactobacillaceae cpdA Bacteria 1UQCQ@1239,3F483@33958,4HG8Z@91061,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase FFAGCILK_01870 543734.LCABL_10100 1e-38 165.6 Lactobacillaceae gcvR ko:K07166 ko00000 Bacteria 1VENW@1239,3F811@33958,4HNJ4@91061,COG3830@1,COG3830@2 NA|NA|NA T Belongs to the UPF0237 family FFAGCILK_01871 543734.LCABL_10110 3e-243 847.4 Lactobacillaceae XK27_08635 ko:K09157 ko00000 Bacteria 1TQG8@1239,3F4H2@33958,4HBTU@91061,COG2848@1,COG2848@2 NA|NA|NA S UPF0210 protein FFAGCILK_01872 543734.LCABL_10120 6.2e-212 743.0 Bacilli coiA 3.6.4.12 ko:K03657,ko:K06198 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TRGD@1239,4HFP5@91061,COG4469@1,COG4469@2 NA|NA|NA S Competence protein FFAGCILK_01873 543734.LCABL_10130 1.1e-113 416.0 Lactobacillaceae yjbH GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 Bacteria 1TQ8K@1239,3F6QR@33958,4HAI8@91061,COG2761@1,COG2761@2 NA|NA|NA Q Thioredoxin FFAGCILK_01874 543734.LCABL_10140 7.5e-106 389.8 Lactobacillaceae yjbK Bacteria 1TTVM@1239,3F4YS@33958,4I4A3@91061,COG4116@1,COG4116@2 NA|NA|NA S CYTH FFAGCILK_01875 543734.LCABL_10150 1.3e-122 445.7 Lactobacillaceae yjbM 2.7.6.5 ko:K07816 ko00230,map00230 R00429 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 1TQ2F@1239,3F452@33958,4HA3Q@91061,COG2357@1,COG2357@2 NA|NA|NA S RelA SpoT domain protein FFAGCILK_01876 543734.LCABL_10160 4.6e-151 540.4 Lactobacillaceae nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 R00104 RC00002,RC00078 ko00000,ko00001,ko01000 iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895 Bacteria 1TRB3@1239,3F45D@33958,4HB08@91061,COG0061@1,COG0061@2 NA|NA|NA F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP FFAGCILK_01877 543734.LCABL_10170 1.3e-170 605.5 Lactobacillaceae rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 ko00000,ko01000,ko03009,ko03016 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 1TS1T@1239,3F4AU@33958,4HBRY@91061,COG0564@1,COG0564@2 NA|NA|NA G Responsible for synthesis of pseudouridine from uracil FFAGCILK_01878 543734.LCABL_10180 2.4e-203 714.5 Lactobacillaceae apbE 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria 1TR9C@1239,3FB4B@33958,4HA6Y@91061,COG1477@1,COG1477@2 NA|NA|NA H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein FFAGCILK_01879 543734.LCABL_10190 2e-82 312.0 Lactobacillaceae cutC GO:0006873,GO:0006875,GO:0006878,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0019725,GO:0030003,GO:0042221,GO:0042592,GO:0046688,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771 ko:K06201 ko00000 Bacteria 1TQYI@1239,3F4NZ@33958,4HE1E@91061,COG3142@1,COG3142@2 NA|NA|NA P Participates in the control of copper homeostasis FFAGCILK_01880 543734.LCABL_10200 8.2e-143 513.1 Lactobacillaceae uppP GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031224,GO:0031226,GO:0042221,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050380,GO:0050896,GO:0071944 3.6.1.27 ko:K06153 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 iYL1228.KPN_03461 Bacteria 1TPFA@1239,3F510@33958,4HB0M@91061,COG1968@1,COG1968@2 NA|NA|NA V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin FFAGCILK_01881 543734.LCABL_10210 6e-199 699.9 Lactobacillaceae pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0017057,GO:0044424,GO:0044444,GO:0044464,GO:0052689 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ3J@1239,3F3RC@33958,4HBHB@91061,COG2706@1,COG2706@2 NA|NA|NA G Lactonase, 7-bladed beta-propeller FFAGCILK_01882 543734.LCABL_10220 2.5e-62 244.6 Lactobacillaceae srlB 2.7.1.198 ko:K02781 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 Bacteria 1VGKB@1239,3F8EZ@33958,4HNJN@91061,COG3731@1,COG3731@2 NA|NA|NA G PTS system glucitol/sorbitol-specific IIA component FFAGCILK_01883 1423732.BALS01000004_gene1205 6e-42 176.4 Lactobacillaceae rpsN GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02954 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEF6@1239,3F7KX@33958,4HKK1@91061,COG0199@1,COG0199@2 NA|NA|NA J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site FFAGCILK_01884 543734.LCABL_10240 5.7e-191 673.3 Lactobacillaceae guaC 1.1.1.205,1.7.1.7 ko:K00088,ko:K00364 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R01134,R08240 RC00143,RC00457,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 iSB619.SA_RS06660 Bacteria 1TNYF@1239,3F45K@33958,4HA55@91061,COG0516@1,COG0516@2 NA|NA|NA F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides FFAGCILK_01885 543734.LCABL_10250 4.8e-171 607.1 Lactobacillaceae corA ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria 1TPI8@1239,3F4B8@33958,4HE7S@91061,COG0598@1,COG0598@2 NA|NA|NA P CorA-like Mg2+ transporter protein FFAGCILK_01886 543734.LCABL_10260 1.1e-155 555.8 Lactobacillaceae rrmA 2.1.1.187 ko:K00563,ko:K10947 R07233 RC00003 ko00000,ko01000,ko03000,ko03009 Bacteria 1V1WE@1239,3F4U3@33958,4HGQ9@91061,COG0500@1,COG2226@2 NA|NA|NA H Methyltransferase FFAGCILK_01887 543734.LCABL_10270 9.4e-97 359.4 Lactobacillaceae trmL GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 ko:K03216 ko00000,ko01000,ko03016 Bacteria 1V3GW@1239,3F42Y@33958,4HFNY@91061,COG0219@1,COG0219@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily FFAGCILK_01888 543734.LCABL_10280 8.4e-72 276.2 Lactobacillaceae WQ51_03320 Bacteria 1VJ7H@1239,3F6JB@33958,4HP0P@91061,COG4835@1,COG4835@2 NA|NA|NA S Protein of unknown function (DUF1149) FFAGCILK_01889 543734.LCABL_10290 0.0 1364.7 Lactobacillaceae ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K03466 ko00000,ko03036 3.A.12 Bacteria 1TPJR@1239,3F3JZ@33958,4H9WA@91061,COG1674@1,COG1674@2 NA|NA|NA D Belongs to the FtsK SpoIIIE SftA family FFAGCILK_01890 543734.LCABL_10300 1.4e-231 808.5 Lactobacillaceae ymfF Bacteria 1TPN6@1239,3F3SA@33958,4H9P5@91061,COG0612@1,COG0612@2 NA|NA|NA S Peptidase M16 inactive domain protein FFAGCILK_01891 543734.LCABL_10310 1.1e-242 845.5 Lactobacillaceae ymfH ko:K07263 ko00000,ko01000,ko01002 Bacteria 1TP5I@1239,3F4MU@33958,4H9YG@91061,COG0612@1,COG0612@2 NA|NA|NA S Peptidase M16 FFAGCILK_01892 543734.LCABL_10320 2e-129 468.4 Lactobacillaceae Bacteria 1V0YW@1239,3FBEA@33958,4ISGK@91061,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase FFAGCILK_01893 543734.LCABL_10330 1.3e-109 402.9 Lactobacillaceae ymfM ko:K15539 ko00000 Bacteria 1V1N7@1239,3F3SM@33958,4HKW3@91061,COG1426@1,COG1426@2 NA|NA|NA S Helix-turn-helix domain FFAGCILK_01894 543734.LCABL_10340 1.9e-104 385.2 Lactobacillaceae pgsA GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 iSB619.SA_RS06365 Bacteria 1V6PJ@1239,3F4BI@33958,4HCEX@91061,COG0558@1,COG0558@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family FFAGCILK_01896 543734.LCABL_10350 1.2e-227 795.4 Lactobacillaceae cinA GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 R02322 RC00100 ko00000,ko00001,ko01000 Bacteria 1TQ1N@1239,3F4I4@33958,4HATN@91061,COG1058@1,COG1058@2,COG1546@1,COG1546@2 NA|NA|NA S Belongs to the CinA family FFAGCILK_01897 543734.LCABL_10360 8e-191 672.9 Lactobacillaceae recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 ko:K03553 ko03440,map03440 M00729 ko00000,ko00001,ko00002,ko03400 Bacteria 1TPD5@1239,3F3KU@33958,4HAG5@91061,COG0468@1,COG0468@2 NA|NA|NA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage FFAGCILK_01898 543734.LCABL_10370 3.1e-231 807.7 Lactobacillaceae rny GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1TP48@1239,3F3WX@33958,4HC9J@91061,COG1418@1,COG1418@2 NA|NA|NA S Endoribonuclease that initiates mRNA decay FFAGCILK_01899 543734.LCABL_10380 2.6e-115 421.4 Lactobacillaceae yvyE 3.4.13.9 ko:K01271 ko00000,ko01000,ko01002 Bacteria 1V6MQ@1239,3F3SQ@33958,4HBIT@91061,COG1739@1,COG1739@2 NA|NA|NA S YigZ family FFAGCILK_01900 543734.LCABL_10390 1.1e-234 818.9 Lactobacillaceae comFA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K02240 M00429 ko00000,ko00002,ko02044 3.A.11.1 Bacteria 1TPZE@1239,3F3TQ@33958,4HB00@91061,COG4098@1,COG4098@2 NA|NA|NA L Helicase C-terminal domain protein FFAGCILK_01901 568703.LGG_00895 6.6e-82 310.5 Lactobacillaceae comFC ko:K02242 M00429 ko00000,ko00002,ko02044 Bacteria 1V73S@1239,3F714@33958,4HJ6R@91061,COG1040@1,COG1040@2 NA|NA|NA S Competence protein FFAGCILK_01902 543734.LCABL_10410 2.1e-97 361.7 Lactobacillaceae hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 ko:K05808 ko00000,ko03009 Bacteria 1V1D5@1239,3F40M@33958,4HFX9@91061,COG1544@1,COG1544@2 NA|NA|NA J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase FFAGCILK_01903 543734.LCABL_10420 0.0 1536.2 Lactobacillaceae secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 1TPEY@1239,3F4DH@33958,4HA22@91061,COG0653@1,COG0653@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane FFAGCILK_01904 1423732.BALS01000004_gene1228 3.9e-188 664.1 Lactobacillaceae prfB GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02836 ko00000,ko03012 Bacteria 1TPSB@1239,3F3SN@33958,4H9N2@91061,COG1186@1,COG1186@2 NA|NA|NA J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA FFAGCILK_01905 543734.LCABL_10450 5.4e-124 450.3 Lactobacillaceae ftsE GO:0000166,GO:0000910,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0017076,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 ko:K09811,ko:K09812 ko02010,map02010 M00256 ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 Bacteria 1TP58@1239,3F4JC@33958,4H9Z2@91061,COG2884@1,COG2884@2 NA|NA|NA D ABC transporter FFAGCILK_01907 543734.LCABL_10470 3e-201 707.6 Lactobacillaceae minJ Bacteria 1TSBA@1239,3F4TP@33958,4HA05@91061,COG0265@1,COG0265@2 NA|NA|NA O Domain present in PSD-95, Dlg, and ZO-1/2. FFAGCILK_01908 543734.LCABL_10480 2.4e-130 471.5 Lactobacillaceae Bacteria 1TPWS@1239,3FC91@33958,4H9KP@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator FFAGCILK_01909 543734.LCABL_10490 1.1e-308 1065.1 Lactobacillaceae phoR 2.7.13.3 ko:K07636,ko:K07652 ko02020,map02020 M00434,M00459 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TQ1H@1239,3F3W2@33958,4HB1B@91061,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase FFAGCILK_01910 543734.LCABL_10500 1.2e-152 545.8 Lactobacillaceae pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TQ5X@1239,3F4ER@33958,4HBEB@91061,COG0226@1,COG0226@2 NA|NA|NA P Phosphate FFAGCILK_01911 543734.LCABL_10510 3.6e-155 554.3 Lactobacillaceae pstC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02037 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TSPP@1239,3F3NI@33958,4HC9H@91061,COG0573@1,COG0573@2 NA|NA|NA P probably responsible for the translocation of the substrate across the membrane FFAGCILK_01912 543734.LCABL_10520 4.8e-157 560.5 Lactobacillaceae pstA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TP74@1239,3F412@33958,4HAKF@91061,COG0581@1,COG0581@2 NA|NA|NA P Phosphate transport system permease protein PstA FFAGCILK_01913 543734.LCABL_10530 1.2e-149 535.8 Lactobacillaceae pstB 3.6.3.27 ko:K02036 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 iLJ478.TM1261 Bacteria 1TP1M@1239,3F3SY@33958,4HAB1@91061,COG1117@1,COG1117@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system FFAGCILK_01914 543734.LCABL_10540 6e-140 503.4 Lactobacillaceae pstB 3.6.3.27 ko:K02036 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 iLJ478.TM1261 Bacteria 1TP1M@1239,3F3SY@33958,4HAB1@91061,COG1117@1,COG1117@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system FFAGCILK_01915 543734.LCABL_10550 1e-119 436.0 Lactobacillaceae phoU ko:K02039 ko00000 Bacteria 1URN3@1239,3F46W@33958,4HEU9@91061,COG0704@1,COG0704@2 NA|NA|NA P Plays a role in the regulation of phosphate uptake FFAGCILK_01916 543734.LCABL_10560 2.4e-262 911.0 Lactobacillaceae yvlB Bacteria 1TS90@1239,3F5QQ@33958,4HDI6@91061,COG2433@1,COG2433@2,COG3595@1,COG3595@2 NA|NA|NA S Putative adhesin FFAGCILK_01917 543734.LCABL_10570 1.4e-30 138.7 Lactobacillaceae Bacteria 1U7RM@1239,2A2TA@1,30R6T@2,3FA2M@33958,4IHNY@91061 NA|NA|NA FFAGCILK_01918 543734.LCABL_10580 4.4e-34 150.6 Lactobacillaceae yvlD ko:K08972 ko00000 Bacteria 1VF4I@1239,3F7IN@33958,4HNXP@91061,COG1950@1,COG1950@2 NA|NA|NA S Mycobacterial 4 TMS phage holin, superfamily IV FFAGCILK_01919 543734.LCABL_10590 2.1e-174 618.2 Lactobacillaceae hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K06023 ko00000,ko01000 Bacteria 1TP5Z@1239,3F3Z3@33958,4HAXR@91061,COG1493@1,COG1493@2 NA|NA|NA F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion FFAGCILK_01920 543734.LCABL_10600 2e-157 561.6 Lactobacillaceae lgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009898,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 ko:K03438,ko:K13292 ko00000,ko01000,ko03009 Bacteria 1TPAK@1239,3F42N@33958,4HAT0@91061,COG0682@1,COG0682@2 NA|NA|NA M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins FFAGCILK_01921 543734.LCABL_10610 6.9e-195 686.4 Lactobacillaceae gpsA GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 R00842,R00844 RC00029 ko00000,ko00001,ko01000 Bacteria 1TQ5P@1239,3F4C8@33958,4HAXW@91061,COG0240@1,COG0240@2 NA|NA|NA I Glycerol-3-phosphate dehydrogenase FFAGCILK_01922 543734.LCABL_10620 6.9e-178 629.8 Lactobacillaceae trxB 1.8.1.9 ko:K00384 ko00450,map00450 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 Bacteria 1TNZS@1239,3F411@33958,4HA4N@91061,COG0492@1,COG0492@2 NA|NA|NA C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family FFAGCILK_01923 543734.LCABL_10630 0.0 1130.9 Lactobacillaceae pgm GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 5.4.2.2,5.4.2.8 ko:K01835,ko:K01840 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114,M00549 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP2N@1239,3F457@33958,4HADU@91061,COG1109@1,COG1109@2 NA|NA|NA G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain FFAGCILK_01924 543734.LCABL_10640 2.2e-114 418.3 Lactobacillaceae Bacteria 1TT12@1239,3F6EC@33958,4HDD2@91061,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal FFAGCILK_01925 543734.LCABL_10650 8.4e-174 616.3 Lactobacillaceae Bacteria 1TT7F@1239,3F619@33958,4HAPG@91061,COG0642@1,COG2205@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain FFAGCILK_01926 1231336.L248_2708 5.3e-92 344.0 Lactobacillaceae ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TP6H@1239,3F6NW@33958,4HGIE@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter FFAGCILK_01927 543734.LCABL_10680 0.0 1456.0 Lactobacillaceae ko:K02004,ko:K09808 ko02010,map02010 M00255,M00258 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.125 Bacteria 1TRAS@1239,3F5WX@33958,4HC7R@91061,COG0577@1,COG0577@2,COG4591@1,COG4591@2 NA|NA|NA V FtsX-like permease family FFAGCILK_01928 543734.LCABL_10690 6.5e-119 433.3 Lactobacillaceae yfbR ko:K07023 ko00000 Bacteria 1TSDU@1239,3F4RZ@33958,4HA8H@91061,COG1896@1,COG1896@2 NA|NA|NA S HD containing hydrolase-like enzyme FFAGCILK_01929 543734.LCABL_10700 0.0 1307.7 Lactobacillaceae uvrB ko:K03702,ko:K08999 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TPKB@1239,3F3XM@33958,4HB81@91061,COG0556@1,COG0556@2 NA|NA|NA L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage FFAGCILK_01930 543734.LCABL_10710 0.0 1912.1 Lactobacillaceae uvrA ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TPIJ@1239,3F4TZ@33958,4HAW9@91061,COG0178@1,COG0178@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate FFAGCILK_01931 543734.LCABL_10720 1.8e-85 322.0 Lactobacillaceae Bacteria 1VJ0U@1239,3FB5N@33958,4HQJ0@91061,COG3247@1,COG3247@2 NA|NA|NA S Short repeat of unknown function (DUF308) FFAGCILK_01932 543734.LCABL_10730 9.7e-166 589.3 Lactobacillaceae rapZ GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 ko:K06958 ko00000,ko03019 Bacteria 1TPS4@1239,3F4NY@33958,4H9KM@91061,COG1660@1,COG1660@2 NA|NA|NA S Displays ATPase and GTPase activities FFAGCILK_01933 543734.LCABL_10740 2.4e-192 677.9 Lactobacillaceae ybhK Bacteria 1TPNV@1239,3F4D5@33958,4HA0Z@91061,COG0391@1,COG0391@2 NA|NA|NA S Required for morphogenesis under gluconeogenic growth conditions FFAGCILK_01934 543734.LCABL_10750 8.2e-171 606.3 Lactobacillaceae whiA GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944 ko:K09762 ko00000 Bacteria 1TP2X@1239,3F4AB@33958,4HB4H@91061,COG1481@1,COG1481@2 NA|NA|NA K May be required for sporulation FFAGCILK_01935 543734.LCABL_10760 3.2e-80 304.3 Lactobacillaceae ohrR Bacteria 1V6G0@1239,3F74F@33958,4HKQR@91061,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein FFAGCILK_01936 543734.LCABL_10770 1.9e-101 375.2 Lactobacillaceae clpP GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 1TQ91@1239,3F3M0@33958,4HA8J@91061,COG0740@1,COG0740@2 NA|NA|NA O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins FFAGCILK_01940 936140.AEOT01000009_gene210 4.2e-63 248.4 Lactobacillaceae ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 2.7.7.7,6.5.1.2 ko:K01972,ko:K02342,ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03430,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03430,map03440 M00260 R00375,R00376,R00377,R00378,R00382 RC00005,RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TRS5@1239,3F546@33958,4HFJA@91061,COG0272@1,COG0272@2,COG2176@1,COG2176@2 NA|NA|NA L EXOIII FFAGCILK_01941 543734.LCABL_11290 4e-187 660.6 Lactobacillaceae cggR ko:K05311 ko00000,ko03000 Bacteria 1TP62@1239,3F53Y@33958,4HAE6@91061,COG2390@1,COG2390@2 NA|NA|NA K Putative sugar-binding domain FFAGCILK_01942 543734.LCABL_11300 2.8e-193 681.0 Lactobacillaceae gap GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009986,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019362,GO:0019637,GO:0019674,GO:0022610,GO:0034641,GO:0036094,GO:0043891,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044464,GO:0044650,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051704,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0097159,GO:0140030,GO:0140032,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 iJR904.b1416,iJR904.b1417 Bacteria 1TNYU@1239,3F3JS@33958,4H9NS@91061,COG0057@1,COG0057@2 NA|NA|NA G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family FFAGCILK_01943 543734.LCABL_11310 1.3e-221 775.4 Lactobacillaceae pgk GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iSB619.SA_RS04145 Bacteria 1TP3H@1239,3F3SC@33958,4H9R3@91061,COG0126@1,COG0126@2 NA|NA|NA F Belongs to the phosphoglycerate kinase family FFAGCILK_01944 543734.LCABL_11320 7.8e-140 503.1 Lactobacillaceae tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iHN637.CLJU_RS19265 Bacteria 1TP2F@1239,3F494@33958,4HAPT@91061,COG0149@1,COG0149@2 NA|NA|NA G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) FFAGCILK_01945 543734.LCABL_11330 1.1e-245 855.5 Lactobacillaceae eno GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Bacteria 1TP2S@1239,3F3JP@33958,4HAKI@91061,COG0148@1,COG0148@2 NA|NA|NA G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis FFAGCILK_01946 543734.LCABL_11340 1.4e-229 802.0 Lactobacillaceae mdt(A) ko:K08217 br01600,ko00000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.22 Bacteria 1TRZB@1239,3F5A0@33958,4HBXV@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily FFAGCILK_01947 543734.LCABL_11350 1.1e-47 195.7 Lactobacillaceae Bacteria 1U7TN@1239,29QBC@1,30BAJ@2,3FA5U@33958,4IHR4@91061 NA|NA|NA FFAGCILK_01948 543734.LCABL_11360 1.1e-292 1011.9 Lactobacillaceae clcA GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006821,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015672,GO:0015698,GO:0015706,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0031404,GO:0034220,GO:0042802,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071705,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 ko:K03281,ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4,2.A.49 iAF1260.b0155,iB21_1397.B21_00153,iBWG_1329.BWG_0148,iE2348C_1286.E2348C_0162,iEC042_1314.EC042_0155,iEC55989_1330.EC55989_0149,iECBD_1354.ECBD_3463,iECDH10B_1368.ECDH10B_0135,iECDH1ME8569_1439.ECDH1ME8569_0149,iECD_1391.ECD_00154,iECIAI1_1343.ECIAI1_0153,iECO103_1326.ECO103_0155,iECSE_1348.ECSE_0156,iECUMN_1333.ECUMN_0152,iECW_1372.ECW_m0152,iEKO11_1354.EKO11_3761,iETEC_1333.ETEC_0151,iEcDH1_1363.EcDH1_3447,iEcE24377_1341.EcE24377A_0160,iEcolC_1368.EcolC_3504,iJO1366.b0155,iSSON_1240.SSON_0167,iUMNK88_1353.UMNK88_159,iWFL_1372.ECW_m0152,iY75_1357.Y75_RS00790,iZ_1308.Z0166 Bacteria 1TPX0@1239,3F3MU@33958,4HD2H@91061,COG0038@1,COG0038@2,COG0569@1,COG0569@2 NA|NA|NA P chloride FFAGCILK_01949 543734.LCABL_11370 2.4e-31 141.0 Lactobacillaceae secG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1VEQR@1239,3F7IQ@33958,4HNKC@91061,COG1314@1,COG1314@2 NA|NA|NA U Preprotein translocase FFAGCILK_01950 543734.LCABL_11380 1.5e-140 505.4 Lactobacillaceae est GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 3.1.1.1 ko:K03928 ko00000,ko01000 Bacteria 1TQ7X@1239,3F5XW@33958,4HBE6@91061,COG1647@1,COG1647@2 NA|NA|NA S Serine aminopeptidase, S33 FFAGCILK_01951 543734.LCABL_11390 0.0 1580.8 Lactobacillaceae rnr ko:K12573,ko:K12585 ko03018,map03018 M00391 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 1TQ1G@1239,3F4EC@33958,4HBBH@91061,COG0557@1,COG0557@2 NA|NA|NA J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs FFAGCILK_01952 543734.LCABL_11400 1.4e-83 315.5 Lactobacillaceae smpB GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 ko:K03664 ko00000 Bacteria 1V3IJ@1239,3F65B@33958,4HGZX@91061,COG0691@1,COG0691@2 NA|NA|NA J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA FFAGCILK_01953 543734.LCABL_11410 2e-177 628.2 Lactobacillaceae yvdE ko:K02529 ko00000,ko03000 Bacteria 1U6Z4@1239,3F3ZC@33958,4HC2A@91061,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor FFAGCILK_01954 543734.LCABL_11420 0.0 1123.6 Lactobacillaceae malL 3.2.1.10,3.2.1.20 ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13,GH31 Bacteria 1UY2T@1239,3FC10@33958,4HBRE@91061,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain FFAGCILK_01955 543734.LCABL_11430 0.0 1219.5 Lactobacillaceae nplT 3.2.1.133,3.2.1.135,3.2.1.54 ko:K01208 ko00500,ko01100,map00500,map01100 R02112,R03122,R11262 ko00000,ko00001,ko01000 GH13 Bacteria 1TNZ0@1239,3F41N@33958,4HB67@91061,COG0366@1,COG0366@2 NA|NA|NA G Belongs to the glycosyl hydrolase 13 family FFAGCILK_01956 543734.LCABL_11440 0.0 1530.0 Lactobacillaceae map2 2.4.1.8 ko:K00691 ko00500,ko01100,map00500,map01100 R01555 RC00049 ko00000,ko00001,ko01000 GH65 Bacteria 1TQMB@1239,3F3PG@33958,4HAVB@91061,COG1554@1,COG1554@2 NA|NA|NA G hydrolase, family 65, central catalytic FFAGCILK_01957 543734.LCABL_11450 2.8e-120 438.0 Lactobacillaceae pgmB GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008801,GO:0009058,GO:0009292,GO:0009294,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016853,GO:0016866,GO:0016868,GO:0019203,GO:0030312,GO:0033554,GO:0034637,GO:0040007,GO:0042221,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046351,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0071704,GO:0071944,GO:1901576 2.4.1.64,3.1.3.12,3.2.1.28,5.4.2.6 ko:K01087,ko:K01194,ko:K01838,ko:K05342 ko00500,ko01100,map00500,map01100 R00010,R02727,R02728,R02778,R11310 RC00017,RC00049,RC00408 ko00000,ko00001,ko00537,ko01000 GH37,GH65 Bacteria 1UY8N@1239,3FCA1@33958,4HHB1@91061,COG0637@1,COG0637@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase FFAGCILK_01958 543734.LCABL_11460 3.7e-210 737.3 Lactobacillaceae msmX ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 ko00000,ko00001,ko00002,ko02000 3.A.1.1 Bacteria 1TP2M@1239,3FC3D@33958,4HAMQ@91061,COG3842@1,COG3842@2 NA|NA|NA P Belongs to the ABC transporter superfamily FFAGCILK_01959 543734.LCABL_11470 0.0 1116.3 Lactobacillaceae dexB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.10,3.2.1.70 ko:K01182,ko:K01215 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13 Bacteria 1TP53@1239,3F41I@33958,4HA1G@91061,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain protein FFAGCILK_01960 543734.LCABL_11480 8.3e-224 782.7 Lactobacillaceae malE ko:K15770 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 Bacteria 1TPU9@1239,3FC77@33958,4HBHE@91061,COG2182@1,COG2182@2 NA|NA|NA G Bacterial extracellular solute-binding protein FFAGCILK_01961 543734.LCABL_11490 1.6e-244 851.7 Lactobacillaceae malF ko:K02025,ko:K02026,ko:K05814,ko:K15771 ko02010,map02010 M00198,M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.3 Bacteria 1TR2A@1239,3F4J1@33958,4HB8H@91061,COG1175@1,COG1175@2 NA|NA|NA P Binding-protein-dependent transport system inner membrane component FFAGCILK_01962 543734.LCABL_11500 3.8e-151 540.8 Lactobacillaceae malG ko:K15772 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 Bacteria 1TRB7@1239,3F4NP@33958,4HC5K@91061,COG3833@1,COG3833@2 NA|NA|NA P ABC transporter permease FFAGCILK_01963 568703.LGG_00947 2.6e-22 111.3 Lactobacillaceae Bacteria 1U7SN@1239,29QAR@1,30B9X@2,3FA4A@33958,4IHQ2@91061 NA|NA|NA FFAGCILK_01964 543734.LCABL_11520 2.5e-23 114.0 Lactobacillaceae ydcG ko:K07729 ko00000,ko03000 Bacteria 1VERT@1239,3F85E@33958,4HNID@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins FFAGCILK_01965 543734.LCABL_11530 9.2e-239 832.4 Lactobacillaceae YSH1 ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1V0AV@1239,3FB9R@33958,4HEB0@91061,COG0595@1,COG0595@2 NA|NA|NA S Metallo-beta-lactamase superfamily FFAGCILK_01966 543734.LCABL_11540 3e-232 810.8 Lactobacillaceae malE ko:K02027,ko:K05813 ko02010,map02010 M00198,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3 Bacteria 1TS64@1239,3F4P5@33958,4HEKH@91061,COG1653@1,COG1653@2 NA|NA|NA G Bacterial extracellular solute-binding protein FFAGCILK_01967 543734.LCABL_11550 1.9e-147 528.5 Lactobacillaceae malF ko:K02026,ko:K05815 ko02010,map02010 M00198,M00207 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3 Bacteria 1TRCP@1239,3FC8I@33958,4HBKE@91061,COG0395@1,COG0395@2 NA|NA|NA G Binding-protein-dependent transport system inner membrane component FFAGCILK_01968 543734.LCABL_11560 5.7e-166 590.1 Lactobacillaceae malG ko:K02025,ko:K05814,ko:K15771 ko02010,map02010 M00198,M00207,M00491 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.3 Bacteria 1TREE@1239,3F464@33958,4HCD0@91061,COG1175@1,COG1175@2 NA|NA|NA P ABC-type sugar transport systems, permease components FFAGCILK_01969 543734.LCABL_11570 5.9e-194 683.3 Lactobacillaceae malK ko:K10112,ko:K17240 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00599,M00602,M00605,M00606 ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.38 iLJ478.TM0421 Bacteria 1TP2M@1239,3FC3J@33958,4HBKK@91061,COG3842@1,COG3842@2 NA|NA|NA P ATPases associated with a variety of cellular activities FFAGCILK_01970 543734.LCABL_11580 3.7e-105 387.5 Lactobacillaceae 3.2.2.20 ko:K01246,ko:K06977 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1V7GR@1239,3FB97@33958,4HJ11@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain FFAGCILK_01971 543734.LCABL_11590 9e-92 342.8 Lactobacillaceae yxjI ko:K21429 ko00000,ko01002 Bacteria 1V8EY@1239,3F698@33958,4HMMS@91061,COG4894@1,COG4894@2 NA|NA|NA FFAGCILK_01972 543734.LCABL_11600 8.3e-157 559.7 Lactobacillaceae ycsE Bacteria 1V5FB@1239,3F58Y@33958,4HGY8@91061,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase FFAGCILK_01973 543734.LCABL_11610 6.6e-130 469.9 Lactobacillaceae ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPSN@1239,3F3W0@33958,4HBTR@91061,COG0692@1,COG0692@2 NA|NA|NA L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine FFAGCILK_01974 543734.LCABL_11620 2.1e-177 628.2 Lactobacillaceae pta 2.3.1.19,2.3.1.8,3.6.3.21 ko:K00625,ko:K00634,ko:K02028,ko:K13788 ko00430,ko00620,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00650,map00680,map00720,map01100,map01120,map01200 M00236,M00357,M00579 R00230,R00921,R01174 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 iSB619.SA_RS03155 Bacteria 1TPQ0@1239,3F3MW@33958,4H9VH@91061,COG0280@1,COG0280@2 NA|NA|NA C phosphate acetyltransferase FFAGCILK_01975 543734.LCABL_11630 1.3e-81 308.9 Lactobacillaceae ydiB GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.1.221,5.1.1.1 ko:K01775,ko:K06925,ko:K07102 ko00473,ko00520,ko01100,ko01502,map00473,map00520,map01100,map01502 R00401,R08968,R11024 RC00002,RC00078,RC00285 ko00000,ko00001,ko01000,ko01011,ko03016 Bacteria 1V6CV@1239,3F3MR@33958,4HIIF@91061,COG0802@1,COG0802@2 NA|NA|NA O Hydrolase, P-loop family FFAGCILK_01976 1154757.Q5C_03840 5.3e-14 84.7 Leuconostocaceae Bacteria 1V624@1239,4AZ20@81850,4IQCC@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins FFAGCILK_01977 543734.LCABL_11640 2.4e-164 584.7 Lactobacillaceae natA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TR06@1239,3F4J8@33958,4H9RX@91061,COG4152@1,COG4152@2 NA|NA|NA S ABC transporter, ATP-binding protein FFAGCILK_01978 543734.LCABL_11650 7.7e-217 759.6 Lactobacillaceae ysdA ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TXRK@1239,3F3KA@33958,4HC9K@91061,COG1668@1,COG1668@2 NA|NA|NA CP ABC-2 family transporter protein FFAGCILK_01979 543734.LCABL_11660 2.4e-98 364.8 Lactobacillaceae dnaQ 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1V57H@1239,3F42Z@33958,4HI1V@91061,COG0847@1,COG0847@2 NA|NA|NA L DNA polymerase III FFAGCILK_01980 543734.LCABL_11670 7.5e-151 539.7 Lactobacillaceae xth GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPFB@1239,3F4GK@33958,4HAIU@91061,COG0708@1,COG0708@2 NA|NA|NA L exodeoxyribonuclease III FFAGCILK_01981 543734.LCABL_11680 2.4e-167 594.7 Lactobacillaceae murB 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 Bacteria 1TP3W@1239,3F40T@33958,4HAD8@91061,COG0812@1,COG0812@2 NA|NA|NA M Cell wall formation FFAGCILK_01982 543734.LCABL_11690 2.7e-52 211.1 Lactobacillaceae yjcE GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 ko:K03316 ko00000 2.A.36 Bacteria 1TR4G@1239,3F42V@33958,4HBJR@91061,COG0025@1,COG0025@2 NA|NA|NA P Sodium proton antiporter FFAGCILK_01983 543734.LCABL_11690 2.9e-285 987.3 Lactobacillaceae yjcE GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 ko:K03316 ko00000 2.A.36 Bacteria 1TR4G@1239,3F42V@33958,4HBJR@91061,COG0025@1,COG0025@2 NA|NA|NA P Sodium proton antiporter FFAGCILK_01984 543734.LCABL_11700 2.9e-96 357.8 Lactobacillaceae puuR Bacteria 1V1K5@1239,3FCDZ@33958,4HHAY@91061,COG1396@1,COG1396@2 NA|NA|NA K Cupin domain FFAGCILK_01985 543734.LCABL_11710 4e-206 723.8 Lactobacillaceae potA 3.6.3.30,3.6.3.31 ko:K02010,ko:K11072 ko02010,map02010 M00190,M00299 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11.1 iSB619.SA_RS05380 Bacteria 1TP2M@1239,3F40H@33958,4H9MS@91061,COG3842@1,COG3842@2 NA|NA|NA P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system FFAGCILK_01986 543734.LCABL_11720 5.5e-147 526.9 Lactobacillaceae potB ko:K11071 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 Bacteria 1TQ7Z@1239,3F4CM@33958,4HAYS@91061,COG1176@1,COG1176@2 NA|NA|NA P ABC transporter permease FFAGCILK_01987 568703.LGG_00971 4.1e-142 510.8 Lactobacillaceae potC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008519,GO:0015075,GO:0015101,GO:0015203,GO:0015399,GO:0015405,GO:0015417,GO:0015595,GO:0015606,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0015848,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072488,GO:0098533,GO:0098655,GO:0098796,GO:0098797,GO:1902047,GO:1902494,GO:1902495,GO:1903711,GO:1904949,GO:1990351 ko:K11070 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 iSBO_1134.SBO_1939 Bacteria 1V0VD@1239,3F3ZN@33958,4H9ZC@91061,COG1177@1,COG1177@2 NA|NA|NA P ABC transporter permease FFAGCILK_01988 543734.LCABL_11740 1.8e-206 724.9 Lactobacillaceae potD ko:K11069 ko02010,map02010 M00299 ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 iSB619.SA_RS05395 Bacteria 1TPY1@1239,3F3W1@33958,4HAET@91061,COG0687@1,COG0687@2 NA|NA|NA P ABC transporter FFAGCILK_01990 543734.LCABL_11760 0.0 1781.5 Lactobacillaceae pacL 3.6.3.8,3.6.3.9 ko:K01537,ko:K01539 ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978 ko00000,ko00001,ko01000,ko04147 3.A.3.1,3.A.3.2 Bacteria 1TPF5@1239,3FC0Z@33958,4HTQ4@91061,COG0474@1,COG0474@2 NA|NA|NA P Cation transporter/ATPase, N-terminus FFAGCILK_01991 543734.LCABL_11770 1.9e-110 405.2 Lactobacillaceae Bacteria 1V3R8@1239,3F6RQ@33958,4HBEK@91061,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator FFAGCILK_01992 543734.LCABL_11780 7.8e-184 649.8 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQG7@1239,3F40D@33958,4H9MK@91061,COG0842@1,COG0842@2 NA|NA|NA V ABC transporter FFAGCILK_01993 543734.LCABL_11790 5.4e-130 470.3 Lactobacillaceae ko:K01990,ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQKM@1239,3F3VV@33958,4HBUK@91061,COG1131@1,COG1131@2 NA|NA|NA V AAA domain, putative AbiEii toxin, Type IV TA system FFAGCILK_01994 543734.LCABL_11800 2.2e-151 541.6 Lactobacillaceae dacA GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 ko:K18672 ko00000,ko01000 Bacteria 1TPRW@1239,3F4N3@33958,4H9XZ@91061,COG1624@1,COG1624@2 NA|NA|NA S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria FFAGCILK_01995 543734.LCABL_11810 6.3e-167 593.6 Lactobacillaceae ybbR GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 Bacteria 1TSIV@1239,3F41C@33958,4HD8Y@91061,COG4856@1,COG4856@2 NA|NA|NA S YbbR-like protein FFAGCILK_01996 543734.LCABL_11820 2.4e-256 891.0 Lactobacillaceae glmM GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 R02060 RC00408 ko00000,ko00001,ko01000 iSB619.SA_RS11275,iSBO_1134.SBO_3206 Bacteria 1TP1X@1239,3F3W5@33958,4HB16@91061,COG1109@1,COG1109@2 NA|NA|NA G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate FFAGCILK_01997 543734.LCABL_11830 0.0 1166.4 Lactobacillaceae glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 iNJ661.Rv3436c,iSB619.SA_RS11245,iYO844.BSU01780 Bacteria 1TPGU@1239,3F467@33958,4H9R4@91061,COG0449@1,COG0449@2 NA|NA|NA M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source FFAGCILK_01999 543734.LCABL_11840 0.0 1211.1 Lactobacillaceae pepF2 ko:K08602 ko00000,ko01000,ko01002 Bacteria 1TQ5W@1239,3F4ZV@33958,4HAN9@91061,COG1164@1,COG1164@2 NA|NA|NA E Oligopeptidase F FFAGCILK_02000 543734.LCABL_11850 1.5e-78 298.9 Lactobacillaceae Bacteria 1VF6Q@1239,3F57S@33958,4HMDE@91061,COG5652@1,COG5652@2 NA|NA|NA S VanZ like family FFAGCILK_02001 543734.LCABL_11860 7.6e-132 476.5 Lactobacillaceae yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 Bacteria 1TPP5@1239,3F4WF@33958,4H9WJ@91061,COG0217@1,COG0217@2 NA|NA|NA K Transcriptional regulatory protein FFAGCILK_02002 543734.LCABL_11870 5.4e-153 547.0 Lactobacillaceae comGA ko:K02243 M00429 ko00000,ko00002,ko02044 3.A.14.1 Bacteria 1TPGE@1239,3F4HY@33958,4HB0C@91061,COG2804@1,COG2804@2 NA|NA|NA NU Type II IV secretion system protein FFAGCILK_02003 543734.LCABL_11880 8.5e-168 596.3 Lactobacillaceae comGB ko:K02244 M00429 ko00000,ko00002,ko02044 3.A.14.1 Bacteria 1U00C@1239,3F3S9@33958,4HGUA@91061,COG1459@1,COG1459@2 NA|NA|NA NU type II secretion system FFAGCILK_02004 1423732.BALS01000047_gene2628 1.9e-26 125.2 Lactobacillaceae ko:K02245 M00429 ko00000,ko00002,ko02044 Bacteria 1U7Q0@1239,2BKDX@1,32EUM@2,3FA01@33958,4IHMB@91061 NA|NA|NA FFAGCILK_02006 568703.LGG_00991 1.3e-22 112.5 Lactobacillaceae Bacteria 1U7TM@1239,2AHWS@1,3189N@2,3FA5S@33958,4IHR3@91061 NA|NA|NA FFAGCILK_02007 1423816.BACQ01000022_gene774 1.9e-19 102.4 Lactobacillaceae ko:K02248 M00429 ko00000,ko00002,ko02044 Bacteria 1U7MZ@1239,29Q7R@1,30B6S@2,3F9XI@33958,4IHJ8@91061 NA|NA|NA FFAGCILK_02008 1423816.BACQ01000022_gene773 9.7e-10 69.7 Lactobacillaceae Bacteria 1U8E6@1239,2BTEK@1,32NKT@2,3FAVY@33958,4IIC3@91061 NA|NA|NA FFAGCILK_02009 543734.LCABL_11940 8.1e-185 652.9 Lactobacillaceae ytxK 2.1.1.72 ko:K00571 ko00000,ko01000,ko02048 Bacteria 1TRIQ@1239,3F4CI@33958,4H9SE@91061,COG0827@1,COG0827@2 NA|NA|NA L N-6 DNA Methylase FFAGCILK_02010 543734.LCABL_11950 9.1e-51 206.5 Lactobacillaceae Bacteria 1U70M@1239,2BH80@1,32B99@2,3F8TH@33958,4IGUY@91061 NA|NA|NA FFAGCILK_02011 543734.LCABL_11960 7.8e-255 885.9 Lactobacillaceae cycA GO:0001761,GO:0001762,GO:0003333,GO:0003674,GO:0005215,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015180,GO:0015187,GO:0015238,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015808,GO:0015816,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0022858,GO:0022889,GO:0032328,GO:0032329,GO:0034220,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0042940,GO:0042941,GO:0042942,GO:0042943,GO:0042944,GO:0042945,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 ko:K03293,ko:K11737 ko00000,ko02000 2.A.3.1,2.A.3.1.7 iECO111_1330.ECO111_5093,iECO26_1355.ECO26_5376,iEcHS_1320.EcHS_A4458,iSbBS512_1146.SbBS512_E4749,iYL1228.KPN_04601 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease FFAGCILK_02012 543734.LCABL_11970 1.3e-147 528.9 Lactobacillaceae arbV 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1V6NX@1239,3FBFU@33958,4IQ5I@91061,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases FFAGCILK_02013 543734.LCABL_11980 2.5e-163 581.3 Lactobacillaceae arbx Bacteria 1UY4M@1239,3F4YZ@33958,4IEY6@91061,COG1442@1,COG1442@2 NA|NA|NA M Glycosyl transferase family 8 FFAGCILK_02014 543734.LCABL_11990 1.8e-181 641.7 Lactobacillaceae arbY GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0016740,GO:0016757,GO:0043170,GO:0044238,GO:0071704,GO:1901576 Bacteria 1UY8Y@1239,3F4YJ@33958,4HBAE@91061,COG1442@1,COG1442@2 NA|NA|NA M family 8 FFAGCILK_02015 543734.LCABL_12000 2.8e-165 587.8 Lactobacillaceae arbZ Bacteria 1V2F4@1239,3F5FU@33958,4IF2T@91061,COG0204@1,COG0204@2 NA|NA|NA I Phosphate acyltransferases FFAGCILK_02016 543734.LCABL_12010 0.0 1553.5 Lactobacillaceae rafA 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 Bacteria 1TQF4@1239,3F3RU@33958,4HA5R@91061,COG3345@1,COG3345@2 NA|NA|NA G alpha-galactosidase FFAGCILK_02019 543734.LCABL_12040 5.8e-70 270.0 Lactobacillaceae Bacteria 1VKM4@1239,2ZY3R@2,3F6IB@33958,4I0CM@91061,COG5658@1 NA|NA|NA S SdpI/YhfL protein family FFAGCILK_02020 543734.LCABL_12050 8e-134 483.0 Lactobacillaceae Bacteria 1TQUQ@1239,3F3QZ@33958,4HAXP@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator FFAGCILK_02021 543734.LCABL_12060 5.7e-272 943.0 Lactobacillaceae Bacteria 1V10X@1239,3F3Z4@33958,4H9UD@91061,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor FFAGCILK_02022 1423816.BACQ01000022_gene737 3.6e-75 287.7 Lactobacillaceae yhbS GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 ko:K03824,ko:K09964 ko00000,ko01000 Bacteria 1W0Z5@1239,3FBB4@33958,4HZAD@91061,COG3153@1,COG3153@2 NA|NA|NA S acetyltransferase FFAGCILK_02023 568703.LGG_01006 5.3e-14 83.2 Lactobacillaceae Bacteria 1U89K@1239,29QKN@1,30BKA@2,3FAQS@33958,4II7H@91061 NA|NA|NA FFAGCILK_02024 543734.LCABL_12100 1.5e-71 275.4 Lactobacillaceae pheB 5.4.99.5 ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 iYO844.BSU27910 Bacteria 1VAJ9@1239,3F6TJ@33958,4HFRC@91061,COG4492@1,COG4492@2 NA|NA|NA S Belongs to the UPF0735 family FFAGCILK_02025 1423816.BACQ01000022_gene734 1e-63 249.6 Lactobacillaceae Bacteria 1U7EM@1239,29Q3G@1,30B24@2,3F9HE@33958,4IHAG@91061 NA|NA|NA FFAGCILK_02026 543734.LCABL_12130 2.9e-54 217.6 Lactobacillaceae Bacteria 1W2PF@1239,28WF1@1,2ZIF8@2,3F8BE@33958,4HZUK@91061 NA|NA|NA FFAGCILK_02027 543734.LCABL_12140 2.6e-252 877.5 Lactobacillaceae uvrX 2.7.7.7 ko:K02346,ko:K03502,ko:K14161 ko00000,ko01000,ko03400 Bacteria 1TP42@1239,3F3WN@33958,4HA1P@91061,COG0389@1,COG0389@2 NA|NA|NA L Belongs to the DNA polymerase type-Y family FFAGCILK_02029 543734.LCABL_12160 1.3e-189 669.1 Lactobacillaceae Bacteria 1UYJN@1239,3FBEE@33958,4HF8I@91061,COG4640@1,COG4640@2 NA|NA|NA S response to antibiotic FFAGCILK_02030 543734.LCABL_12170 4.5e-130 470.7 Lactobacillaceae 3.1.1.5 ko:K10804 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Bacteria 1VIWQ@1239,3F8I7@33958,4HPR5@91061,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase FFAGCILK_02031 543734.LCABL_12180 3.8e-27 127.5 Lactobacillaceae yjgN GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1VA3P@1239,3F733@33958,4HK0T@91061,COG4269@1,COG4269@2 NA|NA|NA S Bacterial protein of unknown function (DUF898) FFAGCILK_02033 543734.LCABL_12190 0.0 1470.3 Lactobacillaceae pcrA 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPSU@1239,3F400@33958,4HB12@91061,COG0210@1,COG0210@2 NA|NA|NA L ATP-dependent DNA helicase FFAGCILK_02034 543734.LCABL_12200 0.0 1314.3 Lactobacillaceae ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 1TPQ3@1239,3F43C@33958,4HA1D@91061,COG0272@1,COG0272@2 NA|NA|NA L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA FFAGCILK_02035 543734.LCABL_12210 5.2e-212 743.4 Lactobacillaceae camS Bacteria 1TSYE@1239,3F3KI@33958,4HBI8@91061,COG4851@1,COG4851@2 NA|NA|NA S sex pheromone FFAGCILK_02036 543734.LCABL_12220 3.7e-45 187.2 Lactobacillaceae gatC 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 iAF987.Gmet_0076 Bacteria 1VEK3@1239,3F7XB@33958,4HNNA@91061,COG0721@1,COG0721@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) FFAGCILK_02037 543734.LCABL_12230 1e-265 922.2 Lactobacillaceae gatA 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 1TP0C@1239,3F4BK@33958,4HBAZ@91061,COG0154@1,COG0154@2 NA|NA|NA J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) FFAGCILK_02038 543734.LCABL_12240 2.3e-278 964.1 Lactobacillaceae gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 ko:K01876,ko:K02434 ko00970,ko01100,map00970,map01100 M00359,M00360 R03905,R04212,R05577 RC00010,RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TPG3@1239,3F44H@33958,4HAFB@91061,COG0064@1,COG0064@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) FFAGCILK_02039 543734.LCABL_12250 4.4e-194 683.7 Lactobacillaceae yegS GO:0001727,GO:0003674,GO:0003824,GO:0004143,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0030258,GO:0044237,GO:0044238,GO:0044255,GO:0046834,GO:0071704 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 R02240 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TQAU@1239,3F447@33958,4H9WD@91061,COG1597@1,COG1597@2 NA|NA|NA G Lipid kinase FFAGCILK_02040 543734.LCABL_12260 7.4e-258 896.0 Lactobacillaceae rumA GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 ko:K03215 ko00000,ko01000,ko03009 Bacteria 1TP4H@1239,3F41R@33958,4HA6M@91061,COG2265@1,COG2265@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family FFAGCILK_02041 543734.LCABL_12270 3.6e-219 767.3 Lactobacillaceae yttB Bacteria 1TPJ6@1239,3F4F9@33958,4HAGJ@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily FFAGCILK_02042 543734.LCABL_12280 5.6e-147 526.9 Lactobacillaceae cof Bacteria 1VAFW@1239,3FC8C@33958,4HWQV@91061,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase FFAGCILK_02043 543734.LCABL_12290 6.9e-164 583.2 Lactobacillaceae Bacteria 1TQQR@1239,3F59Q@33958,4HDT2@91061,COG2326@1,COG2326@2 NA|NA|NA S Polyphosphate nucleotide phosphotransferase, PPK2 family FFAGCILK_02044 543734.LCABL_12300 0.0 1277.3 Lactobacillaceae pepO 3.4.24.71 ko:K01415,ko:K07386 ko00000,ko01000,ko01002,ko04147 Bacteria 1TQTA@1239,3F9J0@33958,4HDSF@91061,COG3590@1,COG3590@2 NA|NA|NA O Peptidase family M13 FFAGCILK_02045 543734.LCABL_12310 1.9e-264 917.9 Lactobacillaceae ydiC1 Bacteria 1TPRN@1239,3F4D4@33958,4HBXJ@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily FFAGCILK_02046 543734.LCABL_12320 8.1e-64 249.6 Bacilli Bacteria 1VBAA@1239,4HN0D@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) family FFAGCILK_02047 543734.LCABL_12330 4.3e-166 590.5 Lactobacillaceae degV Bacteria 1TQDI@1239,3F4II@33958,4HAYQ@91061,COG1307@1,COG1307@2 NA|NA|NA S Uncharacterised protein, DegV family COG1307 FFAGCILK_02048 543734.LCABL_12340 5.4e-119 434.1 Lactobacillaceae qmcA GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 Bacteria 1TPXU@1239,3F4HV@33958,4HGRC@91061,COG0330@1,COG0330@2 NA|NA|NA O prohibitin homologues FFAGCILK_02049 543734.LCABL_12350 1.2e-28 131.7 Lactobacillaceae Bacteria 1U6Z0@1239,29PRV@1,30AQ2@2,3F8R4@33958,4IGT9@91061 NA|NA|NA FFAGCILK_02050 543734.LCABL_12360 7.9e-137 493.0 Lactobacillaceae lys ko:K07273 ko00000 Bacteria 1V484@1239,3FC1I@33958,4HJNJ@91061,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 FFAGCILK_02051 543734.LCABL_12370 3.8e-60 237.3 Lactobacillaceae Bacteria 1VF0I@1239,3F83V@33958,4HPC2@91061,COG5294@1,COG5294@2 NA|NA|NA S Protein of unknown function (DUF1093) FFAGCILK_02052 543734.LCABL_12380 1.7e-60 238.4 Lactobacillaceae Bacteria 1VNS7@1239,2EGZM@1,33ARR@2,3F83W@33958,4HSZW@91061 NA|NA|NA S Domain of unknown function (DUF4828) FFAGCILK_02053 543734.LCABL_12390 2.5e-175 621.3 Lactobacillaceae mocA ko:K22230 ko00562,ko01120,map00562,map01120 R09954 RC00182 ko00000,ko00001,ko01000 Bacteria 1TQSS@1239,3F4EV@33958,4HCIG@91061,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase FFAGCILK_02054 543734.LCABL_12400 4.3e-223 780.4 Lactobacillaceae yfmL GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 1TQ9R@1239,3F4K8@33958,4HANR@91061,COG0513@1,COG0513@2 NA|NA|NA L DEAD DEAH box helicase FFAGCILK_02055 543734.LCABL_12410 1.7e-55 221.9 Bacteria chbA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0009987,GO:0015144,GO:0016043,GO:0016740,GO:0016772,GO:0016773,GO:0022607,GO:0022804,GO:0022857,GO:0034219,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0071702,GO:0071840,GO:0090563,GO:0090566,GO:1901264,GO:1902815 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 iECABU_c1320.ECABU_c17610,iECOK1_1307.ECOK1_1683,iECUMN_1333.ECUMN_2025,iNRG857_1313.NRG857_07575,iUMN146_1321.UM146_09345 Bacteria COG1447@1,COG1447@2 NA|NA|NA G phosphoenolpyruvate-dependent sugar phosphotransferase system FFAGCILK_02056 543734.LCABL_12420 7.3e-71 273.1 Lactobacillaceae Bacteria 1VEZ0@1239,2DQNY@1,337UX@2,3F875@33958,4HPE2@91061 NA|NA|NA S Domain of unknown function (DUF3284) FFAGCILK_02058 1122149.BACN01000068_gene388 1.5e-07 63.5 Lactobacillaceae Bacteria 1V5G2@1239,31PIN@2,3F6X9@33958,4HIRV@91061,arCOG05209@1 NA|NA|NA FFAGCILK_02059 543734.LCABL_12450 0.0 1172.5 Lactobacillaceae recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPN5@1239,3F4PY@33958,4H9QP@91061,COG0514@1,COG0514@2 NA|NA|NA L ATP-dependent DNA helicase RecQ FFAGCILK_02060 543734.LCABL_12460 4.9e-240 836.6 Lactobacillaceae pepS ko:K19689 ko00000,ko01000,ko01002 Bacteria 1TP65@1239,3F53R@33958,4H9W8@91061,COG2309@1,COG2309@2 NA|NA|NA E Thermophilic metalloprotease (M29) FFAGCILK_02061 543734.LCABL_12470 9.4e-112 409.5 Lactobacillaceae Bacteria 1V8EE@1239,3FBGB@33958,4HJF2@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family FFAGCILK_02063 543734.LCABL_12480 4e-259 900.2 Lactobacillaceae Bacteria 1UCBA@1239,3F3JA@33958,4HBCI@91061,COG4320@1,COG4320@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2252) FFAGCILK_02064 543734.LCABL_12490 6e-180 636.7 Lactobacillaceae yihY ko:K07058 ko00000 Bacteria 1U7HM@1239,3F4TC@33958,4H9MJ@91061,COG1295@1,COG1295@2 NA|NA|NA S Belongs to the UPF0761 family FFAGCILK_02065 543734.LCABL_12500 7.2e-80 303.1 Lactobacillaceae fld ko:K03839 ko00000 Bacteria 1V7AG@1239,3F6HY@33958,4HMJF@91061,COG0716@1,COG0716@2 NA|NA|NA C Flavodoxin FFAGCILK_02066 543734.LCABL_12510 4.8e-159 567.0 Lactobacillaceae map GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605 3.4.11.18 ko:K01265 ko00000,ko01000,ko01002 Bacteria 1TQC1@1239,3F3MK@33958,4H9S9@91061,COG0024@1,COG0024@2 NA|NA|NA E Methionine Aminopeptidase FFAGCILK_02067 543734.LCABL_12520 2e-202 711.4 Lactobacillaceae Bacteria 1VVRP@1239,3FBSG@33958,4HGSR@91061,COG0463@1,COG0463@2 NA|NA|NA M Glycosyltransferase like family 2 FFAGCILK_02069 568703.LGG_01060 3.1e-14 84.0 Lactobacillaceae Bacteria 1U82T@1239,2BQ1G@1,32IVS@2,3FAGJ@33958,4II07@91061 NA|NA|NA FFAGCILK_02070 543734.LCABL_12550 4e-198 697.2 Lactobacillaceae mvaK2 2.7.1.36,2.7.1.43,2.7.4.2 ko:K00869,ko:K00938,ko:K16190 ko00040,ko00053,ko00520,ko00900,ko01100,ko01110,ko01130,ko04146,map00040,map00053,map00520,map00900,map01100,map01110,map01130,map04146 M00014,M00095 R01476,R02245,R03245 RC00002,RC00017,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPKP@1239,3F3RZ@33958,4HC93@91061,COG1577@1,COG1577@2 NA|NA|NA I phosphomevalonate kinase FFAGCILK_02071 543734.LCABL_12560 6.3e-168 596.7 Lactobacillaceae galU 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ24@1239,3F45A@33958,4HATY@91061,COG1210@1,COG1210@2 NA|NA|NA M UTP-glucose-1-phosphate uridylyltransferase FFAGCILK_02072 1229520.ADIAL_1901 5.8e-58 231.5 Carnobacteriaceae 3.6.4.12 ko:K03722 ko00000,ko01000,ko03400 Bacteria 1URXJ@1239,27HHM@186828,4HF1N@91061,COG1199@1,COG1199@2 NA|NA|NA KL HELICc2 FFAGCILK_02073 543734.LCABL_12660 1.4e-286 991.5 Lactobacillaceae 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3F3PQ@33958,4HA1W@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family FFAGCILK_02074 543734.LCABL_12670 6.5e-38 162.9 Lactobacillaceae bglH 2.7.1.199,2.7.1.208,2.7.1.211 ko:K02755,ko:K02756,ko:K02757,ko:K02790,ko:K02791,ko:K02809,ko:K02810 ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060 M00266,M00269,M00271 R00811,R02738,R04111 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.3,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9 Bacteria 1TP5X@1239,3F458@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system FFAGCILK_02075 543734.LCABL_12670 4e-255 887.1 Lactobacillaceae bglH 2.7.1.199,2.7.1.208,2.7.1.211 ko:K02755,ko:K02756,ko:K02757,ko:K02790,ko:K02791,ko:K02809,ko:K02810 ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060 M00266,M00269,M00271 R00811,R02738,R04111 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.3,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9 Bacteria 1TP5X@1239,3F458@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system FFAGCILK_02076 543734.LCABL_12680 4.1e-150 537.3 Lactobacillaceae licT2 ko:K02531,ko:K02538,ko:K03488 ko00000,ko03000 Bacteria 1TT5A@1239,3F6PD@33958,4HEI6@91061,COG3711@1,COG3711@2 NA|NA|NA K CAT RNA binding domain FFAGCILK_02077 543734.LCABL_12690 0.0 1697.9 Lactobacillaceae Bacteria 1TRR1@1239,3FC7P@33958,4HCR9@91061,COG4485@1,COG4485@2 NA|NA|NA S Bacterial membrane protein YfhO FFAGCILK_02078 543734.LCABL_12700 0.0 1110.5 Lactobacillaceae Bacteria 1VS0Z@1239,3FBX8@33958,4HJQE@91061,COG5617@1,COG5617@2 NA|NA|NA S Psort location CytoplasmicMembrane, score FFAGCILK_02079 543734.LCABL_12710 8e-171 606.3 Lactobacillaceae yfdH 2.4.2.53 ko:K10012,ko:K12999,ko:K13670 ko00520,ko01503,map00520,map01503 M00721,M00761 R07661 RC00005,RC02954 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko02000 4.D.2.1.8 GT2 Bacteria 1UHWE@1239,3F3JX@33958,4ISA4@91061,COG1216@1,COG1216@2 NA|NA|NA M Glycosyltransferase, group 2 family protein FFAGCILK_02080 568703.LGG_01070 3e-76 291.6 Lactobacillaceae Bacteria 1W6RG@1239,28T4I@1,2ZFDJ@2,3F88M@33958,4HZG4@91061 NA|NA|NA FFAGCILK_02081 543734.LCABL_12730 6.6e-168 596.7 Lactobacillaceae yqjA Bacteria 1TP2T@1239,3F54Y@33958,4HAWV@91061,COG4129@1,COG4129@2 NA|NA|NA S Putative aromatic acid exporter C-terminal domain FFAGCILK_02082 1423775.BAMN01000002_gene2083 3.9e-12 77.0 Lactobacillaceae Bacteria 1U8JQ@1239,2DK9P@1,308YB@2,3FB25@33958,4IIHP@91061 NA|NA|NA FFAGCILK_02083 1423732.BALS01000024_gene2412 1.6e-31 141.4 Lactobacillaceae cspC ko:K03704 ko00000,ko03000 Bacteria 1VEE0@1239,3F7FW@33958,4HNJC@91061,COG1278@1,COG1278@2 NA|NA|NA K Cold shock protein FFAGCILK_02084 543734.LCABL_12750 1.6e-82 312.0 Lactobacillaceae yvbK 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3IC@1239,3F7GI@33958,4HH45@91061,COG0454@1,COG0456@2 NA|NA|NA K GNAT family FFAGCILK_02085 543734.LCABL_12760 5.6e-115 420.2 Lactobacillaceae acmC 3.2.1.17,3.2.1.96 ko:K01185,ko:K01227,ko:K02395 ko00511,map00511 ko00000,ko00001,ko01000,ko02035 Bacteria 1V7JY@1239,3F584@33958,4HIY4@91061,COG1705@1,COG1705@2 NA|NA|NA NU mannosyl-glycoprotein FFAGCILK_02086 543734.LCABL_12770 5.5e-101 373.6 Lactobacillaceae xpt 2.4.2.22,2.4.2.7 ko:K00759,ko:K03816,ko:K09685 ko00230,ko01100,ko01110,map00230,map01100,map01110 R00190,R01229,R02142,R04378 RC00063,RC00122 ko00000,ko00001,ko01000,ko03000,ko04147 Bacteria 1V1DU@1239,3F49S@33958,4HFNW@91061,COG0503@1,COG0503@2 NA|NA|NA F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis FFAGCILK_02087 543734.LCABL_12780 1.8e-240 838.2 Lactobacillaceae pbuX GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 ko:K02824,ko:K03458,ko:K16169,ko:K16170 ko00000,ko02000 2.A.40,2.A.40.1.1,2.A.40.1.2,2.A.40.3.1,2.A.40.3.2 iSB619.SA_RS02140 Bacteria 1TNZZ@1239,3F3Y7@33958,4HBAM@91061,COG2233@1,COG2233@2 NA|NA|NA F xanthine permease FFAGCILK_02088 543734.LCABL_12790 5.6e-203 713.4 Lactobacillaceae purK2 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQCD@1239,3F3YV@33958,4H9M5@91061,COG0026@1,COG0026@2 NA|NA|NA F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) FFAGCILK_02089 543734.LCABL_12800 1.8e-245 854.7 Lactobacillaceae purB GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1095 Bacteria 1TPMM@1239,3F48P@33958,4HACW@91061,COG0015@1,COG0015@2 NA|NA|NA F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily FFAGCILK_02090 543734.LCABL_12810 2.8e-105 387.9 Lactobacillaceae Bacteria 1U77H@1239,29PYD@1,30AWT@2,3F92N@33958,4IH2B@91061 NA|NA|NA FFAGCILK_02091 1423732.BALS01000024_gene2404 5.2e-104 384.0 Lactobacillaceae Bacteria 1U7B2@1239,29Z4F@1,30M23@2,3F98Y@33958,4IH62@91061 NA|NA|NA FFAGCILK_02092 543734.LCABL_12830 0.0 1457.2 Lactobacillaceae ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 R05081,R10849 RC00017 ko00000,ko00001,ko01000 Bacteria 1TRMA@1239,3F3R7@33958,4H9S0@91061,COG1368@1,COG1368@2 NA|NA|NA M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily FFAGCILK_02093 543734.LCABL_12840 1.4e-110 405.6 Lactobacillaceae vanZ Bacteria 1VK3A@1239,3F5EN@33958,4HPCD@91061,COG4767@1,COG4767@2 NA|NA|NA V VanZ like family FFAGCILK_02094 543734.LCABL_12860 2e-152 545.0 Lactobacillaceae glcU ko:K05340 ko00000,ko02000 2.A.7.5 Bacteria 1TQBN@1239,3F4K2@33958,4HAVH@91061,COG4975@1,COG4975@2 NA|NA|NA U sugar transport FFAGCILK_02095 543734.LCABL_12870 5.6e-258 896.3 Lactobacillaceae pgi GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 iLJ478.TM1385 Bacteria 1TP29@1239,3F3XK@33958,4H9VI@91061,COG0166@1,COG0166@2 NA|NA|NA G Belongs to the GPI family FFAGCILK_02096 543734.LCABL_12880 2.9e-226 790.8 Lactobacillaceae Bacteria 1TTJI@1239,3F5DJ@33958,4HEI7@91061,COG0582@1,COG0582@2 NA|NA|NA L Pfam:Integrase_AP2 FFAGCILK_02099 543734.LCABL_12910 2.7e-31 140.6 Lactobacillaceae Bacteria 1U7VR@1239,2AI1X@1,318FN@2,3FA8F@33958,4IHT4@91061 NA|NA|NA FFAGCILK_02100 543734.LCABL_12920 1.2e-60 239.2 Lactobacillaceae Bacteria 1V1KZ@1239,3F7W7@33958,4I1P9@91061,COG3871@1,COG3871@2 NA|NA|NA S Pyridoxamine 5'-phosphate oxidase FFAGCILK_02101 1449343.JQLQ01000002_gene1500 3.9e-21 108.6 Firmicutes Bacteria 1VWPX@1239,2F7D5@1,33ZU6@2 NA|NA|NA FFAGCILK_02102 1423807.BACO01000025_gene815 2.1e-50 205.7 Lactobacillaceae Bacteria 1VE35@1239,2DPC1@1,331GC@2,3F66X@33958,4HMP3@91061 NA|NA|NA S Domain of unknown function (DUF4352) FFAGCILK_02103 1423732.BALS01000070_gene2074 4.3e-71 273.9 Bacilli Bacteria 1W1K0@1239,4I17Z@91061,COG2856@1,COG2856@2 NA|NA|NA E Zn peptidase FFAGCILK_02104 543734.LCABL_12980 1e-54 219.2 Lactobacillaceae 3.4.21.88 ko:K01356 M00729 ko00000,ko00002,ko01000,ko01002,ko03400 Bacteria 1VK84@1239,3F85V@33958,4HRBT@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix domain FFAGCILK_02105 1027396.LMOSA_9210 2.1e-07 61.2 Firmicutes ko:K07727 ko00000,ko03000 Bacteria 1V96W@1239,COG3655@1,COG3655@2 NA|NA|NA K Helix-turn-helix FFAGCILK_02107 1423775.BAMN01000034_gene188 2.6e-16 90.9 Lactobacillaceae Bacteria 1W3RS@1239,2EN2G@1,33FQP@2,3F8R6@33958,4IGTA@91061 NA|NA|NA FFAGCILK_02109 543734.LCABL_13020 1.8e-98 365.2 Lactobacillaceae Bacteria 1U7E6@1239,2ERS9@1,32C80@2,3F9GF@33958,4IHA2@91061 NA|NA|NA FFAGCILK_02111 543734.LCABL_13030 8.6e-15 85.1 Lactobacillaceae Bacteria 1U8B1@1239,29QME@1,30BM2@2,3FASG@33958,4II91@91061 NA|NA|NA FFAGCILK_02114 543734.LCABL_13050 4.4e-147 527.3 Lactobacillaceae recT GO:0000724,GO:0000725,GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0018130,GO:0019438,GO:0032392,GO:0032508,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043150,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 ko:K07455 ko00000,ko03400 Bacteria 1UNDF@1239,3F6D8@33958,4HB2T@91061,COG3723@1,COG3723@2 NA|NA|NA L RecT family FFAGCILK_02115 543734.LCABL_13060 1e-145 522.7 Lactobacillaceae pi112 3.6.4.12 ko:K03657,ko:K16898 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1V1UQ@1239,3F51S@33958,4HGSG@91061,COG1074@1,COG1074@2 NA|NA|NA L PDDEXK-like domain of unknown function (DUF3799) FFAGCILK_02116 543734.LCABL_13070 1.8e-105 389.0 Lactobacillaceae Bacteria 1VHH7@1239,3F8M1@33958,4HK51@91061,COG3935@1,COG3935@2 NA|NA|NA L Replication initiation and membrane attachment FFAGCILK_02117 1423816.BACQ01000027_gene964 3.4e-122 444.5 Lactobacillaceae dnaC 3.4.21.53 ko:K02315,ko:K04076 ko00000,ko01000,ko01002,ko03032 Bacteria 1V36Z@1239,3F6VF@33958,4HXKM@91061,COG1484@1,COG1484@2 NA|NA|NA L IstB-like ATP binding protein FFAGCILK_02119 568703.LGG_01110 1.1e-43 183.0 Lactobacillaceae Bacteria 1U7AM@1239,29Q0P@1,30AZ5@2,3F97Y@33958,4IH5K@91061 NA|NA|NA FFAGCILK_02120 279281.Q6J1V2_9CAUD 4.6e-56 223.8 Siphoviridae Viruses 4QN19@10699,4QQW9@28883,4QZQH@35237 NA|NA|NA S Protein of unknown function (DUF1064) FFAGCILK_02121 146269.A8YQM6_9CAUD 6.6e-100 370.5 Siphoviridae Viruses 4QAIJ@10239,4QM02@10699,4QPXI@28883,4QVZ9@35237 NA|NA|NA S C-5 cytosine-specific DNA methylase FFAGCILK_02123 1423732.BALS01000058_gene2831 6.5e-16 90.9 Lactobacillaceae Bacteria 1U7RI@1239,29Q9Z@1,30B93@2,3FA2I@33958,4IHNV@91061 NA|NA|NA S Protein of unknown function (DUF1642) FFAGCILK_02124 632112.C1KFT5_9CAUD 1.7e-09 68.9 Caudovirales Viruses 4QAM6@10239,4QPNX@28883,4QVEI@35237 NA|NA|NA FFAGCILK_02125 568703.LGG_01117 1.3e-39 169.1 Lactobacillaceae Bacteria 1U7QY@1239,29Q9M@1,30B8Q@2,3FA1A@33958,4IHN8@91061 NA|NA|NA FFAGCILK_02127 146269.A8YQN1_9CAUD 1.7e-70 271.9 Siphoviridae Viruses 4QAU8@10239,4QN1H@10699,4QRF5@28883,4QWW2@35237 NA|NA|NA FFAGCILK_02128 525309.HMPREF0494_1788 5.8e-48 197.6 Firmicutes Bacteria 1UKGB@1239,2DQUP@1,338SW@2 NA|NA|NA S Domain of unknown function (DUF4145) FFAGCILK_02129 1423732.BALS01000107_gene442 1.7e-218 765.0 Lactobacillaceae Bacteria 1VGE5@1239,2C1BV@1,32ZTD@2,3F9J1@33958,4HPF9@91061 NA|NA|NA S GcrA cell cycle regulator FFAGCILK_02131 543734.LCABL_13230 2.6e-79 301.6 Lactobacillaceae ps333 ko:K07474 ko00000 Bacteria 1VAD9@1239,3F6ZJ@33958,4HXMG@91061,COG3728@1,COG3728@2 NA|NA|NA L Terminase small subunit FFAGCILK_02132 543734.LCABL_13240 4.3e-244 850.1 Lactobacillaceae Bacteria 1TT2C@1239,3F3NN@33958,4H9S2@91061,COG1783@1,COG1783@2 NA|NA|NA S Terminase-like family FFAGCILK_02133 568703.LGG_01126 2.9e-252 877.5 Lactobacillaceae Bacteria 1TR67@1239,2DB9U@1,2Z7Z6@2,3FB8U@33958,4HCTZ@91061 NA|NA|NA S Phage portal protein FFAGCILK_02134 568703.LGG_01127 2.7e-172 611.3 Lactobacillaceae Bacteria 1U6KJ@1239,3F3Z8@33958,4HGZW@91061,COG2369@1,COG2369@2 NA|NA|NA S head morphogenesis protein, SPP1 gp7 family FFAGCILK_02135 568703.LGG_01128 4.3e-78 297.7 Lactobacillaceae Bacteria 1VEET@1239,2DNT1@1,32YZX@2,3F7QQ@33958,4HQ00@91061 NA|NA|NA S Domain of unknown function (DUF4355) FFAGCILK_02136 568703.LGG_01129 8.7e-179 632.9 Lactobacillaceae gpG Bacteria 1U6NR@1239,2BZ9Z@1,2Z97E@2,3F6D9@33958,4HF9M@91061 NA|NA|NA FFAGCILK_02137 568703.LGG_01130 7.2e-54 216.5 Lactobacillaceae Bacteria 1VN9C@1239,2EKJJ@1,33E9D@2,3F7K9@33958,4HR20@91061 NA|NA|NA S Phage gp6-like head-tail connector protein FFAGCILK_02138 543734.LCABL_13340 3.4e-46 190.7 Lactobacillaceae Bacteria 1VIHK@1239,2E86K@1,332JW@2,3F8A2@33958,4HZJB@91061 NA|NA|NA FFAGCILK_02139 543734.LCABL_13350 4.4e-56 223.8 Lactobacillaceae Bacteria 1VFPA@1239,2CIV5@1,32ZS6@2,3F8P3@33958,4HQWN@91061 NA|NA|NA S Bacteriophage HK97-gp10, putative tail-component FFAGCILK_02140 543734.LCABL_13360 3.9e-69 267.3 Lactobacillaceae Bacteria 1VMSE@1239,2EIM8@1,33CCI@2,3F7YS@33958,4HRDA@91061 NA|NA|NA S Protein of unknown function (DUF3168) FFAGCILK_02141 568703.LGG_01134 7.4e-101 373.2 Lactobacillaceae Bacteria 1VUVY@1239,2F0XZ@1,33TZM@2,3F76N@33958,4HVU9@91061 NA|NA|NA S Phage tail tube protein FFAGCILK_02142 543734.LCABL_13380 1.5e-50 205.3 Lactobacillaceae Bacteria 1VHHD@1239,2EBTF@1,333J2@2,3FBPF@33958,4HQFJ@91061 NA|NA|NA S Phage tail assembly chaperone protein, TAC FFAGCILK_02143 543734.LCABL_13390 1.6e-55 221.9 Lactobacillaceae Bacteria 1VKIN@1239,2EHS8@1,33BHZ@2,3F7N3@33958,4HR6E@91061 NA|NA|NA FFAGCILK_02144 568703.LGG_01137 2.2e-257 895.6 Lactobacillaceae Bacteria 1W2PZ@1239,3F5MC@33958,4I175@91061,COG5412@1,COG5412@2 NA|NA|NA S phage tail tape measure protein FFAGCILK_02145 568703.LGG_01138 4.9e-149 535.0 Bacilli Bacteria 1VB1N@1239,4HPVS@91061,COG4722@1,COG4722@2 NA|NA|NA S Phage tail protein FFAGCILK_02146 146269.A8YQK1_9CAUD 3.2e-137 496.1 Siphoviridae Viruses 4QAK6@10239,4QKKV@10699,4QPBY@28883,4QUP9@35237 NA|NA|NA S peptidoglycan catabolic process FFAGCILK_02147 146269.A8YQK2_9CAUD 5.1e-31 140.2 Caudovirales Viruses 4QH1E@10239,4QSYR@28883,4QZAD@35237 NA|NA|NA FFAGCILK_02149 146269.A8YQK4_9CAUD 4.3e-65 253.8 Siphoviridae Viruses 4QHK5@10239,4QMA9@10699,4QTTX@28883,4QZM7@35237 NA|NA|NA FFAGCILK_02151 1423732.BALS01000111_gene29 1.5e-66 258.8 Lactobacillaceae Bacteria 1W0SS@1239,2FDCN@1,345EF@2,3F8B6@33958,4HXYE@91061 NA|NA|NA S Bacteriophage holin of superfamily 6 (Holin_LLH) FFAGCILK_02152 1423732.BALS01000111_gene30 4.3e-215 753.8 Lactobacillaceae GO:0008150,GO:0009405,GO:0044419,GO:0051704 ko:K02656,ko:K14196 ko05150,map05150 ko00000,ko00001,ko02035,ko02044 Bacteria 1V16P@1239,3FC13@33958,4HF99@91061,COG1388@1,COG1388@2,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 FFAGCILK_02153 543734.LCABL_13490 2.6e-138 498.0 Lactobacillaceae Bacteria 1V775@1239,28KYP@1,2ZAE6@2,3F6AR@33958,4HMWB@91061 NA|NA|NA S Domain of unknown function DUF1829 FFAGCILK_02154 543734.LCABL_13500 7.8e-48 196.1 Lactobacillaceae ycnE GO:0003674,GO:0003824 3.1.1.29 ko:K01056 ko00000,ko01000,ko03012 Bacteria 1VG4T@1239,3F7H6@33958,4HPNQ@91061,COG1359@1,COG1359@2 NA|NA|NA S Antibiotic biosynthesis monooxygenase FFAGCILK_02156 543734.LCABL_13520 5e-151 540.4 Lactobacillaceae ko:K15051 ko00000 Bacteria 1TR37@1239,3F4MB@33958,4HHHQ@91061,COG2169@1,COG2169@2 NA|NA|NA F DNA/RNA non-specific endonuclease FFAGCILK_02157 543734.LCABL_13530 1.9e-50 206.1 Lactobacillaceae yttA 2.7.13.3 ko:K07184,ko:K07777,ko:K12065,ko:K13527 ko02020,ko03050,map02020,map03050 M00342,M00478 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02044,ko03051 3.A.7.11.1 Bacteria 1VH0K@1239,3FBX9@33958,4ITND@91061,COG2433@1,COG2433@2 NA|NA|NA S Pfam Transposase IS66 FFAGCILK_02158 543734.LCABL_13550 1.2e-229 802.0 Lactobacillaceae wbbX ko:K20444 ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 Bacteria 1VIZB@1239,3F9Q1@33958,4HU4N@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 FFAGCILK_02159 543734.LCABL_13560 5e-173 613.6 Lactobacillaceae yceM 1.1.1.18,1.1.1.369 ko:K00010,ko:K03810 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 R01183,R09951 RC00182 ko00000,ko00001,ko01000 Bacteria 1UZRV@1239,3F4BX@33958,4HEWB@91061,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold FFAGCILK_02160 543734.LCABL_13570 9.9e-85 319.3 Lactobacillaceae guaD GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.12,3.5.4.3,3.5.4.33 ko:K01487,ko:K01493,ko:K11991 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00429 R01663,R01676,R10223 RC00074,RC00204,RC00477 ko00000,ko00001,ko00002,ko01000,ko02044,ko03016 Bacteria 1V7G0@1239,3F6S6@33958,4HMR9@91061,COG0590@1,COG0590@2 NA|NA|NA FJ MafB19-like deaminase FFAGCILK_02162 543734.LCABL_13600 1.7e-79 302.0 Lactobacillaceae tspO ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 9.A.24 Bacteria 1V896@1239,3F6ED@33958,4HK1B@91061,COG3476@1,COG3476@2 NA|NA|NA T TspO/MBR family FFAGCILK_02163 1423732.BALS01000006_gene697 3.2e-13 80.1 Lactobacillaceae Bacteria 1U77Q@1239,29PYH@1,30AWY@2,3F930@33958,4IH2I@91061 NA|NA|NA FFAGCILK_02164 543734.LCABL_13620 1.6e-211 741.9 Lactobacillaceae yttB Bacteria 1TPJ6@1239,3F4F9@33958,4HAGJ@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily FFAGCILK_02165 543734.LCABL_13630 1.4e-104 385.6 Lactobacillaceae Bacteria 1U544@1239,3F4HQ@33958,4IEVF@91061,COG3548@1,COG3548@2 NA|NA|NA S Protein of unknown function (DUF1211) FFAGCILK_02166 543734.LCABL_13640 1.2e-285 988.4 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase FFAGCILK_02168 1423807.BACO01000065_gene2024 1.6e-07 62.4 Lactobacillaceae Bacteria 1W08C@1239,2FI40@1,349WT@2,3F7QX@33958,4HYGC@91061 NA|NA|NA FFAGCILK_02169 543734.LCABL_13680 2.5e-127 461.5 Lactobacillaceae Bacteria 1VDCB@1239,3F50R@33958,4HD4C@91061,COG0406@1,COG0406@2 NA|NA|NA G Phosphoglycerate mutase family FFAGCILK_02170 543734.LCABL_13690 2.6e-120 438.0 Lactobacillaceae Bacteria 1V6CF@1239,3FCEJ@33958,4HJIC@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family FFAGCILK_02171 543734.LCABL_13700 0.0 1100.1 Lactobacillaceae ycfI GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 ko:K06147,ko:K18891 ko02010,map02010 M00708 ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.109,3.A.1.135,3.A.1.21 Bacteria 1TP0B@1239,3F3SP@33958,4H9SC@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter, ATP-binding protein FFAGCILK_02172 543734.LCABL_13710 0.0 1211.1 Lactobacillaceae yfiC ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,3F3PD@33958,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter FFAGCILK_02173 543734.LCABL_13720 1.7e-139 501.9 Lactobacillaceae Bacteria 1VBJA@1239,3F41J@33958,4HSVK@91061,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase FFAGCILK_02174 543734.LCABL_13730 7.5e-163 579.7 Lactobacillaceae 1.13.11.2 ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPRF@1239,3F62I@33958,4HAE7@91061,COG2514@1,COG2514@2 NA|NA|NA S glyoxalase FFAGCILK_02175 543734.LCABL_13740 2.3e-195 688.0 Lactobacillaceae ampC Bacteria 1U828@1239,3FBDZ@33958,4HA0Q@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase FFAGCILK_02176 543734.LCABL_13750 1.1e-261 908.7 Lactobacillaceae murF 6.3.2.10,6.3.2.13 ko:K01928,ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 R02788,R04573,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1TRG9@1239,3FBS5@33958,4HAMY@91061,COG0770@1,COG0770@2 NA|NA|NA M Domain of unknown function (DUF1727) FFAGCILK_02177 543734.LCABL_13760 1.3e-110 405.6 Lactobacillaceae tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 iAF1260.b1238,iBWG_1329.BWG_1065,iECDH10B_1368.ECDH10B_1298,iECDH1ME8569_1439.ECDH1ME8569_1176,iEcDH1_1363.EcDH1_2411,iJO1366.b1238,iJR904.b1238,iPC815.YPO2176,iY75_1357.Y75_RS06470 Bacteria 1TRVM@1239,3F4UE@33958,4HA4A@91061,COG1435@1,COG1435@2 NA|NA|NA F thymidine kinase FFAGCILK_02178 543734.LCABL_13770 1.9e-176 625.2 Lactobacillaceae prfA ko:K02835 ko00000,ko03012 Bacteria 1TQ7V@1239,3F3Q0@33958,4H9MB@91061,COG0216@1,COG0216@2 NA|NA|NA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA FFAGCILK_02179 543734.LCABL_13780 2e-152 545.0 Lactobacillaceae prmB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009007,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0032775,GO:0034641,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044728,GO:0046483,GO:0071704,GO:0090304,GO:0140096,GO:0140097,GO:1901360,GO:1901564 2.1.1.297,2.1.1.298 ko:K02493,ko:K07320 R10806 RC00003,RC03279 ko00000,ko01000,ko03009,ko03012 Bacteria 1TSMA@1239,3F460@33958,4HC6W@91061,COG2890@1,COG2890@2 NA|NA|NA J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif FFAGCILK_02180 543734.LCABL_13790 5.2e-184 650.2 Lactobacillaceae ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87,3.1.3.48 ko:K01104,ko:K07566 R10463 RC00745 ko00000,ko01000,ko03009,ko03016 Bacteria 1TP1I@1239,3F3T1@33958,4HA7W@91061,COG0009@1,COG0009@2 NA|NA|NA J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine FFAGCILK_02181 543734.LCABL_13800 2e-233 814.7 Lactobacillaceae glyA 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQVM@1239,3F4C1@33958,4HA5K@91061,COG0112@1,COG0112@2 NA|NA|NA E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism FFAGCILK_02182 543734.LCABL_13810 5.7e-112 410.2 Lactobacillaceae upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000 iSB619.SA_RS11010 Bacteria 1TPMT@1239,3F4M0@33958,4H9Y0@91061,COG0035@1,COG0035@2 NA|NA|NA F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate FFAGCILK_02183 543734.LCABL_13820 4.6e-126 457.2 Lactobacillaceae atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 iAPECO1_1312.APECO1_2725,iE2348C_1286.E2348C_4048,iEC042_1314.EC042_4125,iECABU_c1320.ECABU_c42230,iECED1_1282.ECED1_4428,iECIAI39_1322.ECIAI39_4342,iECNA114_1301.ECNA114_3887,iECOK1_1307.ECOK1_4187,iECP_1309.ECP_3937,iECS88_1305.ECS88_4160,iECSF_1327.ECSF_3586,iECUMN_1333.ECUMN_4268,iEcSMS35_1347.EcSMS35_4106,iLF82_1304.LF82_0192,iNRG857_1313.NRG857_18615,iUMN146_1321.UM146_18880,iUMNK88_1353.UMNK88_4550,iUTI89_1310.UTI89_C4293,ic_1306.c4666 Bacteria 1TQIT@1239,3F3RE@33958,4H9NV@91061,COG0356@1,COG0356@2 NA|NA|NA C it plays a direct role in the translocation of protons across the membrane FFAGCILK_02184 543734.LCABL_13830 3.3e-27 127.1 Lactobacillaceae atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 1VEHP@1239,3F82A@33958,4HNKQ@91061,COG0636@1,COG0636@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation FFAGCILK_02185 543734.LCABL_13840 3.1e-41 174.9 Lactobacillaceae atpF ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iHN637.CLJU_RS01170,iYO844.BSU36850 Bacteria 1VB85@1239,3F5M8@33958,4HM64@91061,COG0711@1,COG0711@2 NA|NA|NA C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) FFAGCILK_02186 543734.LCABL_13850 1.6e-89 335.5 Lactobacillaceae atpH GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 1VAG3@1239,3F5TZ@33958,4HKFW@91061,COG0712@1,COG0712@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation FFAGCILK_02187 543734.LCABL_13860 9.5e-286 988.8 Lactobacillaceae atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187 Bacteria 1TNZ8@1239,3F3R4@33958,4HAMZ@91061,COG0056@1,COG0056@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit FFAGCILK_02188 543734.LCABL_13870 1.6e-163 582.0 Lactobacillaceae atpG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iLJ478.TM1611,iSB619.SA_RS10970,iYO844.BSU36820 Bacteria 1TPBX@1239,3F40E@33958,4HB0E@91061,COG0224@1,COG0224@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex FFAGCILK_02189 543734.LCABL_13880 1.3e-244 852.0 Lactobacillaceae atpD 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iSB619.SA_RS10965 Bacteria 1TPGF@1239,3F3TF@33958,4HAT6@91061,COG0055@1,COG0055@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits FFAGCILK_02190 543734.LCABL_13890 8.3e-70 269.6 Lactobacillaceae atpC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iJN746.PP_5412,iSbBS512_1146.SbBS512_E4190 Bacteria 1VA89@1239,3F6I6@33958,4HKHS@91061,COG0355@1,COG0355@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane FFAGCILK_02191 543734.LCABL_13900 4.2e-31 140.2 Lactobacillaceae ywzB Bacteria 1U2FQ@1239,3F831@33958,4HNZX@91061,COG4836@1,COG4836@2 NA|NA|NA S Protein of unknown function (DUF1146) FFAGCILK_02192 543734.LCABL_13910 1.1e-178 632.5 Lactobacillaceae mbl ko:K03569 ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 Bacteria 1TP51@1239,3F463@33958,4HA4S@91061,COG1077@1,COG1077@2 NA|NA|NA D Cell shape determining protein MreB Mrl FFAGCILK_02193 568703.LGG_01189 2.2e-18 97.4 Lactobacillaceae epuA Bacteria 1VMAH@1239,2EK0E@1,33DQZ@2,3F8Q0@33958,4I4NP@91061 NA|NA|NA S DNA-directed RNA polymerase subunit beta FFAGCILK_02194 543734.LCABL_13930 9.1e-55 219.2 Lactobacillaceae yidD ko:K08998 ko00000 Bacteria 1VEIG@1239,3F7H1@33958,4HPA3@91061,COG0759@1,COG0759@2 NA|NA|NA S Could be involved in insertion of integral membrane proteins into the membrane FFAGCILK_02195 1423816.BACQ01000017_gene611 1.1e-30 138.7 Lactobacillaceae Bacteria 1U6GX@1239,2BQ47@1,30ACR@2,3F7W8@33958,4IG94@91061 NA|NA|NA S Protein of unknown function (DUF2969) FFAGCILK_02196 543734.LCABL_13950 1.8e-223 781.6 Lactobacillaceae rodA ko:K05837 ko00000,ko03036 Bacteria 1TPGH@1239,3F4J4@33958,4HAV4@91061,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family FFAGCILK_02197 543734.LCABL_13960 9.5e-49 199.1 Lactobacillaceae gcvH ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 Bacteria 1V6WV@1239,3F7WB@33958,4HIMA@91061,COG0509@1,COG0509@2 NA|NA|NA E glycine cleavage FFAGCILK_02198 543734.LCABL_13970 6.7e-212 743.0 Lactobacillaceae argE 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPMJ@1239,3F3N9@33958,4HB39@91061,COG0624@1,COG0624@2 NA|NA|NA E succinyl-diaminopimelate desuccinylase FFAGCILK_02199 543734.LCABL_13980 6.8e-137 493.4 Lactobacillaceae ko:K02073 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TQAS@1239,3F3WP@33958,4HCTA@91061,COG1464@1,COG1464@2 NA|NA|NA P Belongs to the nlpA lipoprotein family FFAGCILK_02201 543734.LCABL_13990 2e-149 535.0 Lactobacillaceae ko:K02073 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TQAS@1239,3F3WP@33958,4HCTA@91061,COG1464@1,COG1464@2 NA|NA|NA P Belongs to the nlpA lipoprotein family FFAGCILK_02202 543734.LCABL_14000 6.1e-191 673.3 Lactobacillaceae metN ko:K02071 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TPPN@1239,3F3U5@33958,4H9VX@91061,COG1135@1,COG1135@2 NA|NA|NA P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system FFAGCILK_02203 543734.LCABL_14010 1.1e-103 382.9 Lactobacillaceae metI ko:K02072 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TRSY@1239,3F48A@33958,4HBEV@91061,COG2011@1,COG2011@2 NA|NA|NA P ABC transporter permease FFAGCILK_02204 543734.LCABL_14020 2.9e-142 511.1 Lactobacillaceae sufC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 ko:K09013 ko00000,ko02000 iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710 Bacteria 1TQ98@1239,3F3XT@33958,4HAD9@91061,COG0396@1,COG0396@2 NA|NA|NA O FeS assembly ATPase SufC FFAGCILK_02205 543734.LCABL_14030 2.5e-189 667.9 Lactobacillaceae sufD ko:K07033,ko:K09015 ko00000 Bacteria 1TRT0@1239,3F4BR@33958,4HB6W@91061,COG0719@1,COG0719@2 NA|NA|NA O FeS assembly protein SufD FFAGCILK_02206 543734.LCABL_14040 6.4e-221 773.1 Lactobacillaceae csdA 2.8.1.7,4.4.1.16 ko:K01766,ko:K11717 ko00450,ko01100,map00450,map01100 R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 Bacteria 1TQ1W@1239,3F3UP@33958,4HA6Z@91061,COG0520@1,COG0520@2 NA|NA|NA E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine FFAGCILK_02207 543734.LCABL_14050 1e-78 299.3 Lactobacillaceae nifU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 ko:K04488 ko00000 Bacteria 1V3H9@1239,3F6WP@33958,4HIJ0@91061,COG0822@1,COG0822@2 NA|NA|NA C SUF system FeS assembly protein, NifU family FFAGCILK_02208 543734.LCABL_14060 1.1e-280 971.8 Lactobacillaceae sufB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 ko:K07033,ko:K09014 ko00000 Bacteria 1TQ21@1239,3F44I@33958,4HA1Z@91061,COG0719@1,COG0719@2 NA|NA|NA O assembly protein SufB FFAGCILK_02209 1423732.BALS01000006_gene651 2.7e-22 110.5 Lactobacillaceae Bacteria 1U84C@1239,29QHS@1,30BH8@2,3FAIG@33958,4II1T@91061 NA|NA|NA FFAGCILK_02210 543734.LCABL_14080 2.9e-66 257.7 Lactobacillaceae yueI Bacteria 1V8ID@1239,3F7A5@33958,4HJTQ@91061,COG5506@1,COG5506@2 NA|NA|NA S Protein of unknown function (DUF1694) FFAGCILK_02211 543734.LCABL_14090 1.5e-180 638.6 Lactobacillaceae Bacteria 1V3Z9@1239,29SNM@1,30DU7@2,3F3VM@33958,4HHKX@91061 NA|NA|NA S Protein of unknown function (DUF2785) FFAGCILK_02212 543734.LCABL_14100 6.8e-116 423.3 Bacilli yhfA Bacteria 1VA1U@1239,4HMKX@91061,COG0637@1,COG0637@2 NA|NA|NA S HAD hydrolase, family IA, variant 3 FFAGCILK_02213 543734.LCABL_14110 2.1e-152 545.0 Lactobacillaceae 2.3.1.19 ko:K00634,ko:K07729 ko00650,ko01100,map00650,map01100 R01174 RC00004,RC02816 ko00000,ko00001,ko01000,ko03000 Bacteria 1VMYH@1239,3F5QH@33958,4ISF0@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins FFAGCILK_02214 543734.LCABL_14120 2.9e-82 311.2 Lactobacillaceae usp6 ko:K03499,ko:K06149 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1V3NY@1239,3F68T@33958,4HIP3@91061,COG0589@1,COG0589@2 NA|NA|NA T universal stress protein FFAGCILK_02215 543734.LCABL_14130 5.4e-38 163.3 Lactobacillaceae Bacteria 1U7ZC@1239,2BNXR@1,32HMR@2,3FACP@33958,4IHWQ@91061 NA|NA|NA FFAGCILK_02216 543734.LCABL_14140 6e-241 839.7 Lactobacillaceae rarA ko:K07478 ko00000 Bacteria 1TPVV@1239,3F3WF@33958,4HAIS@91061,COG2256@1,COG2256@2 NA|NA|NA L recombination factor protein RarA FFAGCILK_02217 543734.LCABL_14150 0.0 1265.0 Lactobacillaceae gshF 6.3.2.2,6.3.2.4 ko:K01919,ko:K01921,ko:K16786,ko:K16787 ko00270,ko00473,ko00480,ko00550,ko01100,ko01502,ko02010,map00270,map00473,map00480,map00550,map01100,map01502,map02010 M00118,M00582 R00894,R01150,R10993 RC00064,RC00090,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TPGX@1239,3F506@33958,4HAMJ@91061,COG1181@1,COG1181@2,COG2918@1,COG2918@2 NA|NA|NA H Belongs to the glutamate--cysteine ligase type 1 family FFAGCILK_02218 543734.LCABL_14160 1.8e-75 288.5 Lactobacillaceae yueI Bacteria 1VFCV@1239,3F64D@33958,4HNNE@91061,COG5506@1,COG5506@2 NA|NA|NA S Protein of unknown function (DUF1694) FFAGCILK_02219 543734.LCABL_14170 6.7e-110 403.3 Lactobacillaceae yktB Bacteria 1UY83@1239,3F62K@33958,4HEDB@91061,COG4493@1,COG4493@2 NA|NA|NA S Belongs to the UPF0637 family FFAGCILK_02220 543734.LCABL_14180 7.6e-123 446.4 Lactobacillaceae sdaAB 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 Bacteria 1U8TZ@1239,3F4UB@33958,4HBD6@91061,COG1760@1,COG1760@2 NA|NA|NA E Serine dehydratase beta chain FFAGCILK_02221 543734.LCABL_14190 2.8e-149 534.6 Lactobacillaceae sdaAA 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 Bacteria 1TP79@1239,3F3X8@33958,4HAI1@91061,COG1760@1,COG1760@2 NA|NA|NA E L-serine dehydratase, iron-sulfur-dependent, alpha subunit FFAGCILK_02222 543734.LCABL_14200 4.3e-121 440.7 Bacteria Bacteria COG0406@1,COG0406@2 NA|NA|NA G alpha-ribazole phosphatase activity FFAGCILK_02223 543734.LCABL_14210 4.7e-154 550.4 Lactobacillaceae msrA 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 ko00000,ko01000 Bacteria 1TS05@1239,3FC52@33958,4HAPI@91061,COG0225@1,COG0225@2 NA|NA|NA O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine FFAGCILK_02224 543734.LCABL_14220 4.7e-171 607.1 Lactobacillaceae Bacteria 1VSDG@1239,3FB7Z@33958,4HUM6@91061,COG1028@1,COG1028@2 NA|NA|NA IQ NAD dependent epimerase/dehydratase family FFAGCILK_02225 543734.LCABL_14230 1.6e-137 495.4 Lactobacillaceae pnuC ko:K03811 ko00000,ko02000 4.B.1.1 Bacteria 1VE5T@1239,3F3MB@33958,4HMNW@91061,COG3201@1,COG3201@2 NA|NA|NA H nicotinamide mononucleotide transporter FFAGCILK_02226 543734.LCABL_14240 1.4e-133 482.3 Lactobacillaceae dck 2.7.1.74 ko:K00893 ko00230,ko00240,ko01100,map00230,map00240,map01100 R00185,R01666 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TPJ1@1239,3F488@33958,4HA9N@91061,COG1428@1,COG1428@2 NA|NA|NA F deoxynucleoside kinase FFAGCILK_02227 543734.LCABL_14250 1.2e-157 562.4 Lactobacillaceae hisK 3.1.3.15 ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V77D@1239,3F6HU@33958,4HHQX@91061,COG1387@1,COG1387@2 NA|NA|NA E Histidinol phosphatase and related hydrolases of the PHP family FFAGCILK_02228 543734.LCABL_14260 9.1e-311 1072.0 Lactobacillaceae oppA ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TNYQ@1239,3F3JE@33958,4HAMK@91061,COG4166@1,COG4166@2 NA|NA|NA E ABC transporter, substratebinding protein FFAGCILK_02229 543734.LCABL_14270 7.5e-158 563.1 Lactobacillaceae Bacteria 1UZKD@1239,3FBXA@33958,4ITNE@91061,COG0642@1,COG2205@2 NA|NA|NA T GHKL domain FFAGCILK_02230 543734.LCABL_14280 2.1e-120 438.3 Lactobacillaceae Bacteria 1UYA6@1239,3F6RJ@33958,4IQ4T@91061,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal FFAGCILK_02231 543734.LCABL_14290 5.8e-169 600.1 Lactobacillaceae bcrA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPBQ@1239,3FC3R@33958,4HAGA@91061,COG1131@1,COG1131@2 NA|NA|NA V AAA domain, putative AbiEii toxin, Type IV TA system FFAGCILK_02232 543734.LCABL_14300 5.2e-99 367.5 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1VMES@1239,2EGU7@1,33AKD@2,3F7PT@33958,4HXVU@91061 NA|NA|NA S ABC-2 family transporter protein FFAGCILK_02233 543734.LCABL_14310 3e-159 567.8 Lactobacillaceae Bacteria 1TP77@1239,3F3VP@33958,4HAZB@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator FFAGCILK_02234 543734.LCABL_14320 1.8e-77 295.0 Lactobacillaceae yphH Bacteria 1V3TP@1239,3FBIH@33958,4HWR6@91061,COG1917@1,COG1917@2 NA|NA|NA S Cupin domain FFAGCILK_02235 543734.LCABL_14330 3.2e-55 220.7 Lactobacillaceae yphJ 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 R03470 RC00938 ko00000,ko00001,ko01000 Bacteria 1VWSB@1239,3F736@33958,4HJ1V@91061,COG0599@1,COG0599@2 NA|NA|NA S decarboxylase FFAGCILK_02236 543734.LCABL_14340 7.8e-117 426.4 Lactobacillaceae Bacteria 1V7A7@1239,3F63T@33958,4HIII@91061,COG0702@1,COG0702@2 NA|NA|NA GM NAD(P)H-binding FFAGCILK_02237 543734.LCABL_14350 9.1e-40 169.1 Lactobacillaceae cadC1 Bacteria 1VF0J@1239,3F8E3@33958,4HP0R@91061,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor FFAGCILK_02238 543734.LCABL_14360 4e-121 440.7 Lactobacillaceae gst 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 Bacteria 1V559@1239,3F6C9@33958,4HRFX@91061,COG0625@1,COG0625@2 NA|NA|NA O Glutathione S-transferase, C-terminal domain FFAGCILK_02239 543734.LCABL_14370 1.2e-109 402.5 Lactobacillaceae Bacteria 1TSHF@1239,3F6S2@33958,4HFC7@91061,COG2207@1,COG2207@2 NA|NA|NA K Psort location Cytoplasmic, score FFAGCILK_02240 543734.LCABL_14380 7.3e-153 546.6 Lactobacillaceae 2.3.1.128 ko:K03789,ko:K03827 ko00000,ko01000,ko03009 Bacteria 1V7Z2@1239,3F7HG@33958,4HPF8@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain FFAGCILK_02241 543734.LCABL_14390 1.2e-25 122.5 Lactobacillaceae Bacteria 1UI2W@1239,3F8D7@33958,4ISXQ@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain FFAGCILK_02242 543734.LCABL_14390 6.5e-40 169.5 Lactobacillaceae Bacteria 1UI2W@1239,3F8D7@33958,4ISXQ@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain FFAGCILK_02243 543734.LCABL_14420 7e-153 546.6 Lactobacillaceae Bacteria 1TYCV@1239,3F572@33958,4HD8F@91061,COG1307@1,COG1307@2 NA|NA|NA S Uncharacterised protein, DegV family COG1307 FFAGCILK_02244 543734.LCABL_14430 4.2e-104 384.0 Lactobacillaceae desR ko:K02479,ko:K07693 ko02020,map02020 M00479 ko00000,ko00001,ko00002,ko02022 Bacteria 1TVTF@1239,3F4VH@33958,4HAJW@91061,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon FFAGCILK_02245 543734.LCABL_14440 9.2e-206 722.6 Lactobacillaceae desK GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K07778 ko02020,map02020 M00479 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TSUE@1239,3F3VR@33958,4HB9N@91061,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase FFAGCILK_02246 543734.LCABL_14450 6.5e-134 483.4 Lactobacillaceae yvfS ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V7QG@1239,3F5Q7@33958,4HFU4@91061,COG0842@1,COG0842@2 NA|NA|NA V ABC-2 type transporter FFAGCILK_02247 543734.LCABL_14460 8.2e-157 559.7 Lactobacillaceae yvfR ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TRM5@1239,3FC3M@33958,4HFBN@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter FFAGCILK_02248 543734.LCABL_14470 7.3e-205 719.9 Lactobacillaceae Bacteria 1U5WE@1239,2DKMH@1,309XQ@2,3F6MD@33958,4IFK1@91061 NA|NA|NA FFAGCILK_02249 543734.LCABL_14480 2.9e-64 251.1 Lactobacillaceae ko:K08365 ko00000,ko03000 Bacteria 1VKCY@1239,3F88Z@33958,4HSCZ@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance FFAGCILK_02250 543734.LCABL_14490 3.3e-47 194.1 Lactobacillaceae Bacteria 1U38N@1239,2EJFD@1,33D6D@2,3F8AW@33958,4HRYN@91061 NA|NA|NA S Protein of unknown function (DUF2568) FFAGCILK_02251 543734.LCABL_14500 1.8e-110 405.2 Lactobacillaceae Bacteria 1U5GF@1239,2C09S@1,30187@2,3F5VJ@33958,4IF7A@91061 NA|NA|NA S Protein of unknown function C-terminus (DUF2399) FFAGCILK_02252 543734.LCABL_14510 4.1e-121 440.7 Lactobacillaceae Bacteria 1U91G@1239,3F938@33958,4IJ1J@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain FFAGCILK_02253 543734.LCABL_14520 3.5e-42 177.2 Lactobacillaceae ko:K07473 ko00000,ko02048 Bacteria 1VGJW@1239,3F7DM@33958,4HR7A@91061,COG3077@1,COG3077@2 NA|NA|NA L RelB antitoxin FFAGCILK_02254 1133569.AHYZ01000076_gene68 1.3e-45 188.7 Lactobacillaceae ko:K19157 ko00000,ko01000,ko02048 Bacteria 1TUTW@1239,3F88F@33958,4IGG3@91061,COG3041@1,COG3041@2 NA|NA|NA S Bacterial toxin of type II toxin-antitoxin system, YafQ FFAGCILK_02256 543734.LCABL_14570 0.0 1379.8 Lactobacillaceae yhgF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 ko:K06959 ko00000 Bacteria 1TPFE@1239,3F415@33958,4HAGY@91061,COG2183@1,COG2183@2 NA|NA|NA K Tex-like protein N-terminal domain protein FFAGCILK_02257 568703.LGG_01253 6.9e-69 266.9 Bacilli Bacteria 1V8IM@1239,4HQD4@91061,COG1476@1,COG1476@2 NA|NA|NA K Cro/C1-type HTH DNA-binding domain FFAGCILK_02259 543734.LCABL_14670 5.2e-296 1023.1 Bacilli Bacteria 1V4JH@1239,2BW5H@1,2ZPYH@2,4HPU9@91061 NA|NA|NA FFAGCILK_02260 543734.LCABL_14750 6.1e-111 406.8 Lactobacillaceae rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 ko:K02986 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TR0J@1239,3F3P0@33958,4HAC9@91061,COG0522@1,COG0522@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit FFAGCILK_02261 543734.LCABL_14760 4.6e-85 320.5 Lactobacillaceae ytsP 1.8.4.14 ko:K08968 ko00270,map00270 R02025 RC00639 ko00000,ko00001,ko01000 Bacteria 1V6GQ@1239,3F6NT@33958,4HH7X@91061,COG1956@1,COG1956@2 NA|NA|NA T GAF domain-containing protein FFAGCILK_02262 543734.LCABL_14770 2e-276 958.0 Lactobacillaceae ezrA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 ko:K06286,ko:K07158 ko00000,ko03036 Bacteria 1TQR7@1239,3F47K@33958,4HA15@91061,COG4477@1,COG4477@2 NA|NA|NA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization FFAGCILK_02263 543734.LCABL_14780 2.8e-214 751.1 Lactobacillaceae iscS2 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1TP21@1239,3F4CD@33958,4HAEE@91061,COG1104@1,COG1104@2 NA|NA|NA E Aminotransferase class V FFAGCILK_02264 543734.LCABL_14790 1.1e-225 788.9 Lactobacillaceae thiI GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07461 ko00000,ko00001,ko01000,ko03016 iECNA114_1301.ECNA114_0400,iECO26_1355.ECO26_0455,iECSF_1327.ECSF_0383,iSDY_1059.SDY_0307 Bacteria 1TPNW@1239,3F3N0@33958,4HAV9@91061,COG0301@1,COG0301@2 NA|NA|NA H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS FFAGCILK_02265 543734.LCABL_14800 4.4e-115 420.6 Lactobacillaceae rex ko:K01926 ko00000,ko03000 Bacteria 1TSMR@1239,3F676@33958,4HB7Q@91061,COG2344@1,COG2344@2 NA|NA|NA K Modulates transcription in response to changes in cellular NADH NAD( ) redox state FFAGCILK_02266 543734.LCABL_14810 0.0 1803.9 Lactobacillaceae valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iLJ478.TM1817 Bacteria 1TPN4@1239,3F3RB@33958,4HB85@91061,COG0525@1,COG0525@2 NA|NA|NA J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner FFAGCILK_02267 543734.LCABL_14820 2e-241 841.3 Lactobacillaceae folC 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0166 Bacteria 1TPX5@1239,3F498@33958,4HBJM@91061,COG0285@1,COG0285@2 NA|NA|NA H Belongs to the folylpolyglutamate synthase family FFAGCILK_02268 543734.LCABL_14830 1.6e-114 418.7 Lactobacillaceae Bacteria 1V1N8@1239,3F56K@33958,4HG58@91061,COG0637@1,COG0637@2 NA|NA|NA S Haloacid dehalogenase-like hydrolase FFAGCILK_02269 543734.LCABL_14840 2e-118 431.8 Lactobacillaceae radC ko:K03630 ko00000 Bacteria 1TQ3K@1239,3F5IM@33958,4HB1W@91061,COG2003@1,COG2003@2 NA|NA|NA L DNA repair protein FFAGCILK_02270 543734.LCABL_14850 1e-179 636.0 Lactobacillaceae mreB ko:K03569 ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 Bacteria 1TP51@1239,3F3ZV@33958,4HA4S@91061,COG1077@1,COG1077@2 NA|NA|NA D cell shape determining protein MreB FFAGCILK_02271 543734.LCABL_14860 7.2e-150 536.6 Lactobacillaceae mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963 ko:K03570 ko00000,ko03036 9.B.157.1 Bacteria 1TR1V@1239,3F3MC@33958,4HB0K@91061,COG1792@1,COG1792@2 NA|NA|NA M Involved in formation and maintenance of cell shape FFAGCILK_02272 543734.LCABL_14870 2.3e-85 321.6 Lactobacillaceae mreD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 ko:K03571 ko00000,ko03036 9.B.157.1 Bacteria 1VEV7@1239,3F6PG@33958,4HPAC@91061,COG2891@1,COG2891@2 NA|NA|NA M rod shape-determining protein MreD FFAGCILK_02273 543734.LCABL_14880 4.4e-115 420.6 Lactobacillaceae minC GO:0000910,GO:0007049,GO:0008150,GO:0009987,GO:0022402,GO:0032506,GO:0036214,GO:0051179,GO:0051301,GO:0061640 ko:K03610 ko00000,ko03036,ko04812 Bacteria 1VAPC@1239,3F61V@33958,4HBTI@91061,COG0850@1,COG0850@2 NA|NA|NA D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization FFAGCILK_02274 543734.LCABL_14890 2.6e-141 508.1 Lactobacillaceae minD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03609 ko00000,ko03036,ko04812 Bacteria 1TP6P@1239,3F3U8@33958,4HB2F@91061,COG2894@1,COG2894@2 NA|NA|NA D Belongs to the ParA family FFAGCILK_02275 543734.LCABL_14900 1.2e-109 402.5 Lactobacillaceae artQ ko:K02029,ko:K02030,ko:K17073,ko:K17074 ko02010,map02010 M00236,M00589 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.20 Bacteria 1V280@1239,3F3VF@33958,4HGMH@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter permease FFAGCILK_02276 543734.LCABL_14910 6.9e-113 413.3 Lactobacillaceae glnQ 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1UYAZ@1239,3F4GP@33958,4HE6M@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter FFAGCILK_02277 543734.LCABL_14920 1.2e-151 542.3 Lactobacillaceae aatB ko:K02029,ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TQNR@1239,3F3WC@33958,4HF14@91061,COG0834@1,COG0834@2 NA|NA|NA ET ABC transporter substrate-binding protein FFAGCILK_02278 543734.LCABL_14930 1.4e-270 938.3 Lactobacillaceae cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0032502,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 ko:K06131 ko00564,ko01100,map00564,map01100 R07390 RC00017 ko00000,ko00001,ko01000 Bacteria 1TPKY@1239,3F542@33958,4H9TI@91061,COG1502@1,COG1502@2 NA|NA|NA I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol FFAGCILK_02279 1423732.BALS01000025_gene2376 4.2e-45 187.2 Lactobacillaceae Bacteria 1U7MX@1239,29Q7N@1,30B6Q@2,3F9XF@33958,4IHJ5@91061 NA|NA|NA FFAGCILK_02280 543734.LCABL_14960 9.8e-79 299.3 Lactobacillaceae mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 ko:K03925 ko00000 Bacteria 1V3JD@1239,3F6K3@33958,4HH23@91061,COG2001@1,COG2001@2 NA|NA|NA K Belongs to the MraZ family FFAGCILK_02281 543734.LCABL_14970 1.1e-170 605.9 Lactobacillaceae rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 ko00000,ko01000,ko03009 Bacteria 1TNZV@1239,3F3MF@33958,4H9U2@91061,COG0275@1,COG0275@2 NA|NA|NA J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA FFAGCILK_02282 568703.LGG_01279 3.1e-49 201.1 Bacteria ftsL Bacteria COG4839@1,COG4839@2 NA|NA|NA D cell division protein FtsL FFAGCILK_02283 543734.LCABL_14990 0.0 1292.7 Lactobacillaceae ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587,ko:K08384,ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 iSSON_1240.SSON_0092 Bacteria 1TP93@1239,3F47N@33958,4H9VQ@91061,COG0768@1,COG0768@2 NA|NA|NA M Penicillin-binding Protein FFAGCILK_02284 543734.LCABL_15000 2e-180 638.3 Lactobacillaceae mraY GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105 Bacteria 1TP8W@1239,3F3YP@33958,4H9TP@91061,COG0472@1,COG0472@2 NA|NA|NA M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan FFAGCILK_02285 543734.LCABL_15010 2e-263 914.4 Lactobacillaceae murD 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1TQ3P@1239,3F49W@33958,4HA5P@91061,COG0771@1,COG0771@2 NA|NA|NA M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) FFAGCILK_02286 543734.LCABL_15020 1.8e-201 708.4 Lactobacillaceae murG GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227,6.3.2.8 ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 R03193,R05032,R05662 RC00005,RC00049,RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 GT28 iLJ478.TM0232,iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089 Bacteria 1TQFT@1239,3F4FW@33958,4HBAQ@91061,COG0707@1,COG0707@2 NA|NA|NA M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) FFAGCILK_02287 543734.LCABL_15030 9.8e-155 552.7 Lactobacillaceae divIB ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Bacteria 1V6V5@1239,3F406@33958,4HDFD@91061,COG1589@1,COG1589@2 NA|NA|NA D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex FFAGCILK_02288 543734.LCABL_15040 2.5e-245 854.4 Lactobacillaceae ftsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562 ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Bacteria 1TP1Z@1239,3F413@33958,4H9NF@91061,COG0849@1,COG0849@2 NA|NA|NA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring FFAGCILK_02289 543734.LCABL_15050 2.8e-227 794.3 Lactobacillaceae ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Bacteria 1TP6W@1239,3F4V1@33958,4H9WZ@91061,COG0206@1,COG0206@2 NA|NA|NA D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity FFAGCILK_02290 543734.LCABL_15060 3.3e-77 294.3 Lactobacillaceae sepF GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0044464,GO:0051301,GO:0071840,GO:0071944,GO:0090529 ko:K09772 ko00000,ko03036 Bacteria 1VER3@1239,3F7MQ@33958,4HKIC@91061,COG1799@1,COG1799@2 NA|NA|NA D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA FFAGCILK_02291 543734.LCABL_15070 2.4e-44 184.5 Bacilli yggT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02221 ko00000,ko02044 Bacteria 1VEKA@1239,4HNJR@91061,COG0762@1,COG0762@2 NA|NA|NA S integral membrane protein FFAGCILK_02292 543734.LCABL_15080 5.7e-146 523.5 Lactobacillaceae ylmH ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 Bacteria 1U5V2@1239,3F48W@33958,4HD3F@91061,COG2302@1,COG2302@2 NA|NA|NA S S4 domain protein FFAGCILK_02293 543734.LCABL_15090 8.8e-86 323.6 Lactobacillaceae divIVA ko:K04074 ko00000,ko03036 Bacteria 1V27M@1239,3FC2J@33958,4HJYN@91061,COG3599@1,COG3599@2 NA|NA|NA D DivIVA protein FFAGCILK_02294 543734.LCABL_15110 0.0 1906.3 Lactobacillaceae ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_0027,iPC815.YPO0475 Bacteria 1TPS7@1239,3F3X4@33958,4HAWB@91061,COG0060@1,COG0060@2 NA|NA|NA J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) FFAGCILK_02295 543734.LCABL_15120 6.9e-36 156.0 Lactobacillaceae cspA ko:K03704 ko00000,ko03000 Bacteria 1W688@1239,3F81I@33958,4I1Y3@91061,COG1278@1,COG1278@2 NA|NA|NA K Cold shock protein FFAGCILK_02296 543734.LCABL_15130 6.7e-154 550.1 Lactobacillaceae pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TQ5X@1239,3F4ER@33958,4HBEB@91061,COG0226@1,COG0226@2 NA|NA|NA P Phosphate FFAGCILK_02297 543734.LCABL_15140 2.1e-263 914.4 Lactobacillaceae ydiC1 Bacteria 1TPRN@1239,3F4D4@33958,4HBXJ@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily FFAGCILK_02298 543734.LCABL_15150 1.8e-210 738.4 Lactobacillaceae yaaN Bacteria 1TQVX@1239,3F5KJ@33958,4H9Z6@91061,COG3853@1,COG3853@2 NA|NA|NA P Toxic anion resistance protein (TelA) FFAGCILK_02299 543734.LCABL_15160 2e-115 421.8 Lactobacillaceae xpaC Bacteria 1VB0U@1239,3F7AZ@33958,4HMAQ@91061,COG4915@1,COG4915@2 NA|NA|NA S 5-bromo-4-chloroindolyl phosphate hydrolysis protein FFAGCILK_02300 543734.LCABL_15170 6e-94 350.1 Lactobacillaceae nudF 3.6.1.13 ko:K01515 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000 iHN637.CLJU_RS05505,iSB619.SA_RS07540,iYO844.BSU23610 Bacteria 1V6F5@1239,3F53J@33958,4HII9@91061,COG0494@1,COG0494@2 NA|NA|NA L ADP-ribose pyrophosphatase FFAGCILK_02301 1423732.BALS01000015_gene1677 2.1e-28 131.3 Lactobacillaceae Bacteria 1U6XT@1239,2A67P@1,30AP5@2,3F8PG@33958,4IGS2@91061 NA|NA|NA FFAGCILK_02302 543734.LCABL_15190 4.8e-123 447.2 Lactobacillaceae mtnN 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 Bacteria 1U7WK@1239,3F4HE@33958,4HB8K@91061,COG0775@1,COG0775@2 NA|NA|NA E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively FFAGCILK_02303 543734.LCABL_15200 1.7e-218 765.0 Lactobacillaceae iscS 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1TP21@1239,3F3RF@33958,4HA6H@91061,COG1104@1,COG1104@2 NA|NA|NA E Aminotransferase class V FFAGCILK_02304 543734.LCABL_15210 2.9e-57 227.6 Lactobacillaceae XK27_04120 Bacteria 1VDSF@1239,2DHWG@1,32U9W@2,3F7E3@33958,4HP9N@91061 NA|NA|NA S Putative amino acid metabolism FFAGCILK_02305 543734.LCABL_15220 0.0 1522.3 Lactobacillaceae uvrA2 Bacteria 1TR1H@1239,3F50Y@33958,4H9RE@91061,COG0178@1,COG0178@2 NA|NA|NA L ABC transporter FFAGCILK_02306 543734.LCABL_15230 2.2e-240 837.8 Lactobacillaceae mnmA GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 Bacteria 1TPIZ@1239,3F4N5@33958,4HBJ6@91061,COG0482@1,COG0482@2 NA|NA|NA J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 FFAGCILK_02308 543734.LCABL_15240 9.9e-123 446.0 Lactobacillaceae pgm6 5.4.2.11,5.4.2.12 ko:K01834,ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1V6ES@1239,3F3U3@33958,4HGZI@91061,COG0406@1,COG0406@2 NA|NA|NA G phosphoglycerate mutase FFAGCILK_02309 543734.LCABL_15250 4.1e-116 424.1 Lactobacillaceae Bacteria 1VFGR@1239,3F4MD@33958,4IBSH@91061,COG0457@1,COG0457@2 NA|NA|NA S Repeat protein FFAGCILK_02310 543734.LCABL_15260 0.0 1594.7 Lactobacillaceae recD2 3.1.11.5 ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPZH@1239,3F44X@33958,4HATQ@91061,COG0507@1,COG0507@2 NA|NA|NA L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity FFAGCILK_02311 543734.LCABL_15270 5.5e-244 849.7 Lactobacillaceae els Bacteria 1TRPM@1239,3F5HJ@33958,4HD22@91061,COG4552@1,COG4552@2 NA|NA|NA S Sterol carrier protein domain FFAGCILK_02312 543734.LCABL_15280 1.6e-182 645.2 Lactobacillaceae ytlR 2.7.1.91 ko:K04718 ko00600,ko01100,ko04020,ko04071,ko04072,ko04370,ko04371,ko04666,ko05152,map00600,map01100,map04020,map04071,map04072,map04370,map04371,map04666,map05152 M00100 R01926,R02976 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V7DZ@1239,3F5GQ@33958,4HBUD@91061,COG1597@1,COG1597@2 NA|NA|NA I Diacylglycerol kinase catalytic domain FFAGCILK_02313 543734.LCABL_15290 0.0 1110.9 Lactobacillaceae rnjA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1TQ9G@1239,3F3TT@33958,4HAAP@91061,COG0595@1,COG0595@2 NA|NA|NA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay FFAGCILK_02314 543734.LCABL_15300 2.9e-31 140.6 Lactobacillaceae ykzG Bacteria 1VEI7@1239,3F807@33958,4HNSK@91061,COG5503@1,COG5503@2 NA|NA|NA S Belongs to the UPF0356 family FFAGCILK_02315 543734.LCABL_15310 9.5e-69 266.2 Lactobacillaceae Bacteria 1VQPI@1239,2C389@1,2ZQCN@2,3F79N@33958,4I0G9@91061 NA|NA|NA FFAGCILK_02316 543734.LCABL_15320 2.5e-46 191.0 Lactobacillaceae Bacteria 1U8HD@1239,29QQZ@1,30BQS@2,3FAZK@33958,4IIF9@91061 NA|NA|NA FFAGCILK_02317 543734.LCABL_15330 1.2e-100 372.5 Lactobacillaceae def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.31,3.5.1.88 ko:K01450,ko:K01462 ko00270,ko00630,map00270,map00630 R00653 RC00165,RC00323 ko00000,ko00001,ko01000 Bacteria 1V70B@1239,3F3YH@33958,4HH0G@91061,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions FFAGCILK_02318 1423816.BACQ01000014_gene486 5.2e-89 334.3 Lactobacillaceae Bacteria 1U7D2@1239,29Q2F@1,30B13@2,3F9EB@33958,4IH8M@91061 NA|NA|NA S E1-E2 ATPase FFAGCILK_02319 543734.LCABL_15360 1.5e-211 741.9 Lactobacillaceae pdhA 1.2.4.1,1.2.4.4 ko:K00161,ko:K00166 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00036,M00307 R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1TQDG@1239,3F3JK@33958,4H9PQ@91061,COG1071@1,COG1071@2 NA|NA|NA C Dehydrogenase E1 component FFAGCILK_02320 543734.LCABL_15370 6.2e-182 643.3 Lactobacillaceae pdhB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944,GO:0140030,GO:0140032 1.2.4.1,1.2.4.4 ko:K00162,ko:K00167,ko:K21417 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00036,M00307 R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2496c,iYO844.BSU14590 Bacteria 1TP3J@1239,3F4RV@33958,4HA4H@91061,COG0022@1,COG0022@2 NA|NA|NA C Transketolase, C-terminal domain protein FFAGCILK_02321 543734.LCABL_15380 2.4e-266 924.5 Lactobacillaceae pdhC 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1TR5N@1239,3F3RR@33958,4HA7A@91061,COG0508@1,COG0508@2 NA|NA|NA C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex FFAGCILK_02322 543734.LCABL_15390 5.3e-259 899.8 Lactobacillaceae lpdA GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006103,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006520,GO:0006544,GO:0006546,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015036,GO:0016054,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017144,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019464,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0036211,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045250,GO:0045252,GO:0045254,GO:0046390,GO:0046395,GO:0046483,GO:0046496,GO:0046872,GO:0046914,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0065007,GO:0065008,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0097159,GO:0106077,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 iAPECO1_1312.APECO1_1869,iEcolC_1368.EcolC_3543,iPC815.YPO3417,iSFV_1184.SFV_0107,iUMN146_1321.UM146_23385 Bacteria 1TP1W@1239,3F426@33958,4HB3K@91061,COG1249@1,COG1249@2 NA|NA|NA C Dehydrogenase FFAGCILK_02323 543734.LCABL_15400 2.8e-157 561.2 Lactobacillaceae 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1UFQZ@1239,3F4RQ@33958,4IEWQ@91061,COG0039@1,COG0039@2 NA|NA|NA C L-malate dehydrogenase activity FFAGCILK_02324 543734.LCABL_15410 2.4e-46 191.0 Lactobacillaceae yktA ko:K16509 ko00000 Bacteria 1VEK8@1239,3F80A@33958,4HNKR@91061,COG4476@1,COG4476@2 NA|NA|NA S Belongs to the UPF0223 family FFAGCILK_02325 543734.LCABL_15420 1.3e-145 522.3 Lactobacillaceae suhB 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR4E@1239,3F5BB@33958,4HB92@91061,COG0483@1,COG0483@2 NA|NA|NA G Belongs to the inositol monophosphatase superfamily FFAGCILK_02326 543734.LCABL_15430 0.0 1199.9 Lactobacillaceae typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 ko:K06207 ko00000 Bacteria 1TQ5Y@1239,3F3UK@33958,4HAQ6@91061,COG1217@1,COG1217@2 NA|NA|NA T GTP-binding protein TypA FFAGCILK_02327 543734.LCABL_15440 2.6e-211 741.1 Lactobacillaceae ftsW ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 2.A.103.1 Bacteria 1TPT7@1239,3F4IK@33958,4HAEV@91061,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family FFAGCILK_02328 543734.LCABL_15450 0.0 2254.6 Lactobacillaceae pyc GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.1 ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHP9@1239,3F4U7@33958,4IS56@91061,COG1038@1,COG1038@2 NA|NA|NA C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second FFAGCILK_02329 543734.LCABL_15460 7.3e-62 243.0 Lactobacillaceae ylbG Bacteria 1VF52@1239,3F70V@33958,4HNTH@91061,COG4471@1,COG4471@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2129) FFAGCILK_02330 543734.LCABL_15470 1.7e-99 368.6 Lactobacillaceae rsmD 2.1.1.171 ko:K08316 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 1V3JF@1239,3F505@33958,4HGXT@91061,COG0742@1,COG0742@2 NA|NA|NA L RNA methyltransferase, RsmD family FFAGCILK_02331 543734.LCABL_15480 3.3e-86 324.3 Lactobacillaceae coaD GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0015939,GO:0015940,GO:0016043,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046390,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 iPC815.YPO0053,iSDY_1059.SDY_4064 Bacteria 1V3MR@1239,3F6YS@33958,4HH47@91061,COG0669@1,COG0669@2 NA|NA|NA H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate FFAGCILK_02332 543734.LCABL_15490 3.8e-182 644.0 Lactobacillaceae ylbL ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Bacteria 1TRUF@1239,3F4KY@33958,4HBAY@91061,COG3480@1,COG3480@2 NA|NA|NA T Belongs to the peptidase S16 family FFAGCILK_02333 543734.LCABL_15500 7.8e-115 419.9 Lactobacillaceae comEA ko:K02237 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 1VA3W@1239,3F7NP@33958,4HKJ1@91061,COG1555@1,COG1555@2 NA|NA|NA L Competence protein ComEA FFAGCILK_02334 543734.LCABL_15510 0.0 1437.2 Lactobacillaceae comEC ko:K02238 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 1TS9U@1239,3F3VT@33958,4H9M4@91061,COG0658@1,COG0658@2,COG2333@1,COG2333@2 NA|NA|NA S Competence protein ComEC FFAGCILK_02335 543734.LCABL_15520 1.3e-169 602.4 Lactobacillaceae holA 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TRM0@1239,3F3TP@33958,4HBB4@91061,COG1466@1,COG1466@2 NA|NA|NA L DNA polymerase III delta subunit FFAGCILK_02336 543734.LCABL_15530 5.1e-35 153.3 Lactobacillaceae rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02968 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEGX@1239,3F7D8@33958,4HNJS@91061,COG0268@1,COG0268@2 NA|NA|NA J Binds directly to 16S ribosomal RNA FFAGCILK_02337 543734.LCABL_15540 5.4e-43 179.9 Lactobacillaceae rpsO GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02956 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VA5C@1239,3F7DV@33958,4HKE9@91061,COG0184@1,COG0184@2 NA|NA|NA J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome FFAGCILK_02338 1423816.BACQ01000014_gene466 8.1e-51 207.2 Lactobacillaceae Bacteria 1U7FW@1239,29Q46@1,30B2W@2,3F9K7@33958,4IHBY@91061 NA|NA|NA FFAGCILK_02339 543734.LCABL_15560 0.0 1101.3 Lactobacillaceae rnjB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1TQ9G@1239,3F3U9@33958,4HAAP@91061,COG0595@1,COG0595@2 NA|NA|NA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay FFAGCILK_02340 543734.LCABL_15570 2.2e-165 588.2 Bacilli Bacteria 1W4AR@1239,4HZIS@91061,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat FFAGCILK_02341 543734.LCABL_15580 2.1e-224 784.6 Lactobacillaceae tuf GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009274,GO:0009275,GO:0009986,GO:0010339,GO:0016020,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035821,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 ko:K02358,ko:K15771 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 3.A.1.1.16,3.A.1.1.2 Bacteria 1TPKC@1239,3F3ZP@33958,4HAEH@91061,COG0050@1,COG0050@2 NA|NA|NA J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis FFAGCILK_02342 1423816.BACQ01000013_gene462 1.1e-68 266.2 Lactobacillaceae Bacteria 1TQXN@1239,3F4Y5@33958,4HBHT@91061,COG5434@1,COG5434@2 NA|NA|NA M Protein of unknown function (DUF3737) FFAGCILK_02343 1423732.BALS01000013_gene1548 1.8e-120 438.7 Lactobacillaceae cobB ko:K12410 ko00000,ko01000 Bacteria 1TQKD@1239,3F9HM@33958,4HC4I@91061,COG0846@1,COG0846@2 NA|NA|NA K Sir2 family FFAGCILK_02344 1423732.BALS01000013_gene1549 1.8e-60 238.4 Lactobacillaceae pcaC 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 R03470 RC00938 ko00000,ko00001,ko01000 Bacteria 1V78I@1239,3F5I2@33958,4HKFY@91061,COG0599@1,COG0599@2 NA|NA|NA S Carboxymuconolactone decarboxylase family FFAGCILK_02345 1423816.BACQ01000013_gene459 2.2e-58 231.5 Lactobacillaceae rmeD ko:K13640 ko00000,ko03000 Bacteria 1VB69@1239,3FC69@33958,4HN6R@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance FFAGCILK_02346 543734.LCABL_15590 6.9e-301 1039.3 Lactobacillaceae yknV ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 3.A.1.106 Bacteria 1TP0B@1239,3F3PD@33958,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter FFAGCILK_02347 543734.LCABL_15600 3.8e-222 777.3 Lactobacillaceae tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K03545 ko00000 Bacteria 1TQQ8@1239,3F40B@33958,4H9Q8@91061,COG0544@1,COG0544@2 NA|NA|NA D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase FFAGCILK_02348 543734.LCABL_15610 2.9e-232 810.8 Lactobacillaceae clpX GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 Bacteria 1TQ00@1239,3F41K@33958,4H9U4@91061,COG1219@1,COG1219@2 NA|NA|NA O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP FFAGCILK_02349 543734.LCABL_15620 5.8e-106 390.2 Lactobacillaceae engB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03978 ko00000,ko03036 Bacteria 1TSPW@1239,3F44G@33958,4HBXZ@91061,COG0218@1,COG0218@2 NA|NA|NA D Necessary for normal cell division and for the maintenance of normal septation FFAGCILK_02350 543734.LCABL_15630 7.8e-48 196.1 Lactobacillaceae MA20_27270 Bacteria 1VIQA@1239,3F6WJ@33958,4HM6C@91061,COG1694@1,COG1694@2 NA|NA|NA S mazG nucleotide pyrophosphohydrolase FFAGCILK_02351 543734.LCABL_15640 1.3e-20 104.8 Lactobacillaceae Bacteria 1U8B8@1239,2AYHS@1,31QM8@2,3FASP@33958,4II98@91061 NA|NA|NA FFAGCILK_02352 543734.LCABL_15650 1.5e-259 901.7 Lactobacillaceae arpJ ko:K02029,ko:K02030,ko:K17073,ko:K17074 ko02010,map02010 M00236,M00589 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.20 Bacteria 1TPM3@1239,3F48Y@33958,4HAS2@91061,COG0765@1,COG0765@2,COG0834@1,COG0834@2 NA|NA|NA P ABC transporter permease FFAGCILK_02353 543734.LCABL_15660 1.8e-133 481.9 Lactobacillaceae glnQ 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1TNYD@1239,3F3QQ@33958,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein FFAGCILK_02354 543734.LCABL_15670 0.0 1192.2 Lactobacillaceae uvrC ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TP4B@1239,3F3MY@33958,4H9QH@91061,COG0322@1,COG0322@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision FFAGCILK_02355 543734.LCABL_15690 0.0 1209.5 Lactobacillaceae fruA 2.7.1.194,2.7.1.200,2.7.1.202,2.7.1.204 ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 M00273,M00279,M00283,M00306,M00550,M00807 R03232,R05570,R07671,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1,4.A.5,4.A.5.1,4.A.7.1 Bacteria 1TPKU@1239,3F44C@33958,4H9KR@91061,COG1299@1,COG1299@2,COG1445@1,COG1445@2,COG1762@1,COG1762@2 NA|NA|NA GT Phosphotransferase System FFAGCILK_02356 543734.LCABL_15700 6.7e-170 603.2 Lactobacillaceae pfkB 2.7.1.11,2.7.1.144,2.7.1.56 ko:K00882,ko:K00917,ko:K16370 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00345 R00756,R02071,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ36@1239,3F3SG@33958,4HANU@91061,COG1105@1,COG1105@2 NA|NA|NA H Belongs to the carbohydrate kinase PfkB family. LacC subfamily FFAGCILK_02357 543734.LCABL_15710 6.6e-131 473.4 Lactobacillaceae fruR ko:K03436 ko00000,ko03000 Bacteria 1TSF8@1239,3F3JB@33958,4HDT9@91061,COG1349@1,COG1349@2 NA|NA|NA K DeoR C terminal sensor domain FFAGCILK_02358 543734.LCABL_15720 3.7e-243 847.0 Lactobacillaceae obg GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043021,GO:0043022,GO:0043167,GO:0043168,GO:0043934,GO:0044424,GO:0044464,GO:0044877,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03979 ko00000,ko01000,ko03009 Bacteria 1TPX7@1239,3F4ZA@33958,4H9P8@91061,COG0536@1,COG0536@2 NA|NA|NA S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control FFAGCILK_02359 543734.LCABL_15730 0.0 1286.9 Lactobacillaceae oatA Bacteria 1TPTG@1239,3F3WT@33958,4HB7R@91061,COG1835@1,COG1835@2 NA|NA|NA I Acyltransferase FFAGCILK_02360 543734.LCABL_15740 1.9e-183 648.3 Lactobacillaceae rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016891,GO:0016893,GO:0016896,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Bacteria 1TRGP@1239,3F4F1@33958,4HABM@91061,COG1234@1,COG1234@2 NA|NA|NA J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA FFAGCILK_02361 543734.LCABL_15750 1e-142 512.7 Lactobacillaceae XK27_05435 1.1.1.100 ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TSJ3@1239,3FC9J@33958,4HDU5@91061,COG0300@1,COG0300@2 NA|NA|NA S Enoyl-(Acyl carrier protein) reductase FFAGCILK_02362 543734.LCABL_15760 8.2e-49 199.5 Lactobacillaceae yrvD ko:K08992 ko00000 Bacteria 1VIG5@1239,3F7IW@33958,4HP5V@91061,COG5416@1,COG5416@2 NA|NA|NA S Lipopolysaccharide assembly protein A domain FFAGCILK_02363 543734.LCABL_15770 0.0 1652.9 Lactobacillaceae clpB GO:0003674,GO:0005488,GO:0005515,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0042802,GO:0043170,GO:0044238,GO:0071704,GO:1901564 ko:K03694,ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Bacteria 1TPMU@1239,3F3RV@33958,4HACY@91061,COG0542@1,COG0542@2 NA|NA|NA O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE FFAGCILK_02364 543734.LCABL_15780 3.5e-28 130.2 Lactobacillaceae rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 ko:K02911 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1VKMZ@1239,3F7ZT@33958,4HR2Q@91061,COG0333@1,COG0333@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL32 family FFAGCILK_02365 543734.LCABL_15790 2.8e-94 351.3 Lactobacillaceae M1-874 ko:K13638,ko:K13640 ko00000,ko03000 Bacteria 1V7Z4@1239,3FB3S@33958,4HJXK@91061,COG0789@1,COG0789@2 NA|NA|NA K Domain of unknown function (DUF1836) FFAGCILK_02366 543734.LCABL_15800 6e-304 1049.3 Lactobacillaceae cpdB 3.1.3.6,3.1.4.16 ko:K01119 ko00230,ko00240,map00230,map00240 R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135 RC00078,RC00296 ko00000,ko00001,ko01000 Bacteria 1TPV2@1239,3FC24@33958,4HB9S@91061,COG0737@1,COG0737@2 NA|NA|NA F 5'-nucleotidase, C-terminal domain FFAGCILK_02367 543734.LCABL_15810 1e-125 456.4 Lactobacillaceae Bacteria 1VWGD@1239,2F31P@1,33VWT@2,3F4CP@33958,4HWD9@91061 NA|NA|NA FFAGCILK_02368 641146.HMPREF9020_01154 1.1e-236 825.5 Bifidobacteriales Bacteria 2GJK7@201174,4D1TR@85004,COG3464@1,COG3464@2 NA|NA|NA L Transposase FFAGCILK_02369 1423732.BALS01000013_gene1578 2.5e-18 97.4 Lactobacillaceae Bacteria 1U6V1@1239,2BAS8@1,3247E@2,3F8J0@33958,4IGNY@91061 NA|NA|NA S Protein of unknown function (DUF2929) FFAGCILK_02370 543734.LCABL_15830 0.0 2150.9 Lactobacillaceae dnaE 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TPYG@1239,3F4AM@33958,4H9T3@91061,COG0587@1,COG0587@2 NA|NA|NA L DNA polymerase FFAGCILK_02371 543734.LCABL_15840 7e-178 629.8 Lactobacillaceae pfkA GO:0003674,GO:0003824,GO:0003872,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061615,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.11 ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 iYO844.BSU29190 Bacteria 1TPF4@1239,3F4CC@33958,4HAPN@91061,COG0205@1,COG0205@2 NA|NA|NA F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis FFAGCILK_02372 543734.LCABL_15850 0.0 1131.3 Lactobacillaceae pyk GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009986,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0022607,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40,2.7.7.4 ko:K00873,ko:K00958 ko00010,ko00230,ko00261,ko00450,ko00620,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00261,map00450,map00620,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050,M00176,M00596 R00200,R00430,R00529,R01138,R01858,R02320,R04929 RC00002,RC00015,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 iECO103_1326.ECO103_1819,iPC815.YPO2393 Bacteria 1TPGG@1239,3F3JU@33958,4H9VY@91061,COG0469@1,COG0469@2 NA|NA|NA G Belongs to the pyruvate kinase family FFAGCILK_02373 543734.LCABL_15860 1.5e-72 278.9 Lactobacillaceae yeaL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1V7JN@1239,3FB78@33958,4IRT9@91061,COG2707@1,COG2707@2 NA|NA|NA S Protein of unknown function (DUF441) FFAGCILK_02374 543734.LCABL_15870 4.9e-162 577.0 Lactobacillaceae cvfB ko:K00243 ko00000 Bacteria 1TQ1Z@1239,3F44W@33958,4HDAZ@91061,COG2996@1,COG2996@2 NA|NA|NA S S1 domain FFAGCILK_02375 543734.LCABL_15880 4.8e-165 587.0 Lactobacillaceae xerD ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 1TQRG@1239,3F3V9@33958,4HAEX@91061,COG4974@1,COG4974@2 NA|NA|NA D recombinase XerD FFAGCILK_02376 543734.LCABL_15890 2e-67 261.5 Lactobacillaceae ribT ko:K02859 ko00000 Bacteria 1VAD7@1239,3F7QC@33958,4HKR2@91061,COG0454@1,COG0456@2 NA|NA|NA K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases FFAGCILK_02377 543734.LCABL_15900 2e-124 451.8 Lactobacillaceae scpA GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K05896 ko00000,ko03036 Bacteria 1TRW3@1239,3FCCZ@33958,4HA6Q@91061,COG1354@1,COG1354@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves FFAGCILK_02378 543734.LCABL_15910 5.5e-107 393.7 Lactobacillaceae scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K06024 ko00000,ko03036 Bacteria 1V6HI@1239,3F5RN@33958,4HIQ0@91061,COG1386@1,COG1386@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves FFAGCILK_02379 543734.LCABL_15920 6.7e-136 490.0 Lactobacillaceae rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.21,5.4.99.22 ko:K06178,ko:K06182,ko:K06183 ko00000,ko01000,ko03009 Bacteria 1TP68@1239,3F402@33958,4H9MU@91061,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family FFAGCILK_02380 543734.LCABL_15930 1.2e-95 355.9 Lactobacillaceae Bacteria 1V4BW@1239,3F4HD@33958,4HHFT@91061,COG3601@1,COG3601@2 NA|NA|NA U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins FFAGCILK_02381 543734.LCABL_15940 3.2e-45 187.2 Lactobacillaceae fer ko:K05337 ko00000 Bacteria 1VAC2@1239,3F7KF@33958,4HKG7@91061,COG1141@1,COG1141@2 NA|NA|NA C 4Fe-4S single cluster domain of Ferredoxin I FFAGCILK_02382 543734.LCABL_15950 1.9e-178 631.7 Lactobacillaceae ypbB 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQU9@1239,3F45N@33958,4HJ71@91061,COG4955@1,COG4955@2 NA|NA|NA S Helix-turn-helix domain FFAGCILK_02383 543734.LCABL_15960 3.6e-263 913.7 Lactobacillaceae recQ1 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPN5@1239,3F4PY@33958,4H9QP@91061,COG0514@1,COG0514@2 NA|NA|NA L ATP-dependent DNA helicase RecQ FFAGCILK_02384 543734.LCABL_15970 6.1e-66 257.3 Lactobacillaceae Bacteria 1VFEU@1239,3F6WV@33958,4HNW5@91061,COG1388@1,COG1388@2 NA|NA|NA M Lysin motif FFAGCILK_02385 543734.LCABL_15980 2e-115 421.8 Lactobacillaceae cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.17.7.4,2.5.1.19,2.7.1.26,2.7.4.25,2.7.7.2,6.3.2.1 ko:K00800,ko:K00945,ko:K02945,ko:K03527,ko:K03977,ko:K11753,ko:K13799 ko00240,ko00400,ko00410,ko00740,ko00770,ko00900,ko01100,ko01110,ko01130,ko01230,ko03010,map00240,map00400,map00410,map00740,map00770,map00900,map01100,map01110,map01130,map01230,map03010 M00022,M00052,M00096,M00119,M00125,M00178 R00158,R00161,R00512,R00549,R01665,R02473,R03460,R05884,R08210 RC00002,RC00017,RC00096,RC00141,RC00350,RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03009,ko03011 iPC815.YPO1391,iSDY_1059.SDY_2348 Bacteria 1V3IA@1239,3F3W4@33958,4HFZE@91061,COG0283@1,COG0283@2 NA|NA|NA F Belongs to the cytidylate kinase family. Type 1 subfamily FFAGCILK_02386 543734.LCABL_15990 1.1e-221 775.8 Lactobacillaceae rpsA 1.17.7.4 ko:K02945,ko:K03527 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 M00096,M00178 R05884,R08210 RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 Bacteria 1TQ9N@1239,3F4DQ@33958,4H9PX@91061,COG0539@1,COG0539@2 NA|NA|NA J Ribosomal protein S1 FFAGCILK_02387 543734.LCABL_16000 2e-244 851.3 Lactobacillaceae der GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.399,1.1.1.95 ko:K00058,ko:K03977 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko03009,ko04147 Bacteria 1TPNM@1239,3F4V0@33958,4HAJ6@91061,COG1160@1,COG1160@2 NA|NA|NA S GTPase that plays an essential role in the late steps of ribosome biogenesis FFAGCILK_02388 1423732.BALS01000037_gene108 1.1e-40 172.2 Lactobacillaceae hup ko:K03530 ko00000,ko03032,ko03036,ko03400 Bacteria 1V9XQ@1239,3F6YN@33958,4HKF2@91061,COG0776@1,COG0776@2 NA|NA|NA L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions FFAGCILK_02389 543734.LCABL_16020 6.7e-237 826.2 Lactobacillaceae Bacteria 1TT97@1239,3F3ND@33958,4HAIA@91061,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat protein FFAGCILK_02390 543734.LCABL_16030 2.6e-147 528.1 Lactobacillaceae ypjC Bacteria 1TRAU@1239,3F44R@33958,4H9UY@91061,COG1284@1,COG1284@2 NA|NA|NA S Uncharacterised 5xTM membrane BCR, YitT family COG1284 FFAGCILK_02391 543734.LCABL_16040 3.4e-222 777.3 Lactobacillaceae cca 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 Bacteria 1TQ2A@1239,3F3VH@33958,4HB2W@91061,COG0617@1,COG0617@2 NA|NA|NA J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate FFAGCILK_02392 543734.LCABL_16050 1.3e-84 318.9 Lactobacillaceae Bacteria 1V54W@1239,2A42J@1,30SMC@2,3F3R1@33958,4HGI5@91061 NA|NA|NA FFAGCILK_02393 543734.LCABL_16060 0.0 1225.3 Lactobacillaceae yfmR ko:K15738 ko00000,ko02000 3.A.1.120.6 Bacteria 1TPAX@1239,3FC7W@33958,4H9TK@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter, ATP-binding protein FFAGCILK_02394 543734.LCABL_16070 6e-190 669.8 Lactobacillaceae thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSIR@1239,3F3SB@33958,4H9QS@91061,COG0207@1,COG0207@2 NA|NA|NA F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis FFAGCILK_02395 543734.LCABL_16080 9.7e-91 339.3 Lactobacillaceae folA 1.5.1.3,1.5.1.47,2.1.1.45,3.5.4.12 ko:K00287,ko:K00560,ko:K01493,ko:K05896,ko:K17364 ko00240,ko00670,ko00790,ko01100,ko01523,map00240,map00670,map00790,map01100,map01523 M00053,M00126,M00429,M00840 R00936,R00937,R00939,R00940,R01663,R02101,R02235,R02236,R03388,R11765 RC00074,RC00109,RC00110,RC00158,RC00219,RC00332,RC01584 ko00000,ko00001,ko00002,ko01000,ko02044,ko03036 Bacteria 1VB80@1239,3F6Y4@33958,4HIGJ@91061,COG0262@1,COG0262@2 NA|NA|NA H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis FFAGCILK_02396 543734.LCABL_16090 1.3e-114 419.1 Lactobacillaceae hly ko:K11068 ko00000,ko02042 Bacteria 1TSFK@1239,3F578@33958,4HAT2@91061,COG1272@1,COG1272@2 NA|NA|NA S protein, hemolysin III FFAGCILK_02397 543734.LCABL_16100 5e-146 523.9 Lactobacillaceae DegV Bacteria 1TRZ4@1239,3F4CW@33958,4HBR8@91061,COG1307@1,COG1307@2 NA|NA|NA S EDD domain protein, DegV family FFAGCILK_02398 543734.LCABL_16110 6.9e-153 546.6 Lactobacillaceae ypmR GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0016298,GO:0016787,GO:0016788,GO:0052689 Bacteria 1V1HR@1239,3F4N0@33958,4HDXS@91061,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase FFAGCILK_02399 543734.LCABL_16120 3e-113 414.5 Lactobacillaceae ypmS Bacteria 1VF0K@1239,3F5K5@33958,4HIYN@91061,COG4698@1,COG4698@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2140) FFAGCILK_02400 543734.LCABL_16130 2.9e-84 317.8 Lactobacillaceae msrA 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 ko00000,ko01000 Bacteria 1V1MJ@1239,3FBG0@33958,4HG4U@91061,COG0225@1,COG0225@2 NA|NA|NA C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine FFAGCILK_02401 543734.LCABL_16140 1.1e-39 168.7 Lactobacillaceae yozE Bacteria 1VFI4@1239,3F7ZP@33958,4HR7P@91061,COG4479@1,COG4479@2 NA|NA|NA S Belongs to the UPF0346 family FFAGCILK_02402 543734.LCABL_16150 4.2e-240 837.0 Lactobacillaceae ctpA 3.4.21.102 ko:K03797 ko00000,ko01000,ko01002 Bacteria 1TPBI@1239,3F3SS@33958,4HAKE@91061,COG0793@1,COG0793@2 NA|NA|NA M Belongs to the peptidase S41A family FFAGCILK_02403 568703.LGG_01406 9e-37 159.5 Lactobacillaceae Bacteria 1VA3N@1239,2DMTK@1,32TKW@2,3FC0V@33958,4HMQA@91061 NA|NA|NA FFAGCILK_02404 411467.BACCAP_04522 8e-78 299.3 Clostridia Bacteria 1U1MA@1239,24BCE@186801,2C0IE@1,2Z7YA@2 NA|NA|NA S Psort location Cytoplasmic, score FFAGCILK_02405 411467.BACCAP_04521 6.5e-14 86.3 Clostridia Bacteria 1V2CR@1239,24GTF@186801,28IAD@1,2Z8CZ@2 NA|NA|NA FFAGCILK_02406 1423816.BACQ01000012_gene400 2.9e-61 242.3 Lactobacillaceae Bacteria 1U7WF@1239,29FCS@1,302AF@2,3FA9B@33958,4IHTU@91061 NA|NA|NA FFAGCILK_02407 543734.LCABL_16180 6.5e-190 669.8 Lactobacillaceae gap GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009986,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019362,GO:0019637,GO:0019674,GO:0022610,GO:0034641,GO:0036094,GO:0043891,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044464,GO:0044650,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051704,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0097159,GO:0140030,GO:0140032,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 iJR904.b1416,iJR904.b1417 Bacteria 1TNYU@1239,3F60U@33958,4H9NS@91061,COG0057@1,COG0057@2 NA|NA|NA G Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain FFAGCILK_02408 543734.LCABL_16190 1.7e-140 505.4 Lactobacillaceae Bacteria 1TSJ6@1239,3F6KA@33958,4HC63@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix domain FFAGCILK_02409 543734.LCABL_16210 1.5e-158 565.5 Lactobacillaceae ylqF GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840 ko:K14540 ko00000,ko03009 Bacteria 1TQGK@1239,3F3MI@33958,4HA4D@91061,COG1161@1,COG1161@2 NA|NA|NA S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity FFAGCILK_02410 543734.LCABL_16220 2.5e-138 498.0 Lactobacillaceae rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1V1D6@1239,3F3JC@33958,4HB7M@91061,COG0164@1,COG0164@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids FFAGCILK_02411 543734.LCABL_16230 2.1e-146 525.0 Lactobacillaceae dprA GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 ko:K04096 ko00000 Bacteria 1TPP7@1239,3F41U@33958,4HGWM@91061,COG0758@1,COG0758@2 NA|NA|NA LU DNA protecting protein DprA FFAGCILK_02412 543734.LCABL_16250 0.0 1343.9 Lactobacillaceae topA 5.99.1.2 ko:K03168 ko00000,ko01000,ko03032,ko03400 Bacteria 1TPUS@1239,3F3VS@33958,4HA6C@91061,COG0550@1,COG0550@2 NA|NA|NA L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone FFAGCILK_02413 543734.LCABL_16260 1.2e-249 868.6 Lactobacillaceae trmFO GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 ko:K04094 ko00000,ko01000,ko03016,ko03036 Bacteria 1TP67@1239,3F3WW@33958,4HB27@91061,COG1206@1,COG1206@2 NA|NA|NA J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs FFAGCILK_02414 543734.LCABL_16270 2.1e-168 598.2 Lactobacillaceae xerC ko:K03733,ko:K04763 ko00000,ko03036 Bacteria 1TPQB@1239,3F44K@33958,4HARA@91061,COG4974@1,COG4974@2 NA|NA|NA D Belongs to the 'phage' integrase family. XerC subfamily FFAGCILK_02415 543734.LCABL_16280 7.2e-92 343.2 Lactobacillaceae hslV GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 ko:K01419 ko00000,ko01000,ko01002 Bacteria 1TPXK@1239,3F4HS@33958,4H9PD@91061,COG5405@1,COG5405@2 NA|NA|NA O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery FFAGCILK_02416 543734.LCABL_16290 2.6e-258 897.5 Lactobacillaceae hslU GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 ko:K03667 ko00000,ko03110 Bacteria 1TPKQ@1239,3F3WB@33958,4HA83@91061,COG1220@1,COG1220@2 NA|NA|NA O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis FFAGCILK_02417 543734.LCABL_16300 1.8e-172 611.7 Lactobacillaceae lacX 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 1U26T@1239,3F3KT@33958,4HA4J@91061,COG2017@1,COG2017@2 NA|NA|NA G Aldose 1-epimerase FFAGCILK_02418 543734.LCABL_16310 1.7e-108 398.7 Lactobacillaceae plsY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15,3.5.1.104 ko:K08591,ko:K22278 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1VA3J@1239,3F543@33958,4HC55@91061,COG0344@1,COG0344@2 NA|NA|NA I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP FFAGCILK_02419 543734.LCABL_16320 0.0 1285.8 Lactobacillaceae parE GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034335,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 ko:K02470,ko:K02622 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1TQCF@1239,3F430@33958,4H9UC@91061,COG0187@1,COG0187@2 NA|NA|NA L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule FFAGCILK_02420 543734.LCABL_16330 0.0 1581.6 Lactobacillaceae parC GO:0005575,GO:0005622,GO:0005623,GO:0009330,GO:0032991,GO:0044424,GO:0044464 5.99.1.3 ko:K02469,ko:K02621 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1TRE7@1239,3F3MJ@33958,4HAQB@91061,COG0188@1,COG0188@2 NA|NA|NA L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule FFAGCILK_02421 543734.LCABL_16340 0.0 1542.3 Lactobacillaceae pflB 2.3.1.54 ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 R00212,R06987 RC00004,RC01181,RC02742,RC02833 ko00000,ko00001,ko01000 Bacteria 1TPTF@1239,3F53K@33958,4H9RD@91061,COG1882@1,COG1882@2 NA|NA|NA C Pyruvate formate lyase-like FFAGCILK_02422 543734.LCABL_16350 5.6e-171 606.7 Lactobacillaceae pflA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0018307,GO:0019538,GO:0033554,GO:0036211,GO:0043170,GO:0043364,GO:0043365,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070283,GO:0071704,GO:1901564 1.97.1.4 ko:K04069 R04710 ko00000,ko01000 iECOK1_1307.ECOK1_0925,iEcE24377_1341.EcE24377A_0980,iEcSMS35_1347.EcSMS35_2219,iYL1228.KPN_00930 Bacteria 1TPK2@1239,3F472@33958,4HACV@91061,COG1180@1,COG1180@2 NA|NA|NA C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine FFAGCILK_02423 543734.LCABL_16360 2.2e-179 634.8 Lactobacillaceae Bacteria 1UYRT@1239,3FBIB@33958,4IQQ1@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain FFAGCILK_02424 543734.LCABL_16370 8.1e-171 606.3 Lactobacillaceae ppaC GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464 3.6.1.1 ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 1TPH6@1239,3F3PJ@33958,4H9T8@91061,COG1227@1,COG1227@2 NA|NA|NA C inorganic pyrophosphatase FFAGCILK_02425 543734.LCABL_16380 4e-209 733.8 Lactobacillaceae xerS GO:0000150,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360 ko:K04763 ko00000,ko03036 Bacteria 1URNQ@1239,3FBHV@33958,4HEPI@91061,COG4974@1,COG4974@2 NA|NA|NA L Belongs to the 'phage' integrase family FFAGCILK_02426 543734.LCABL_16390 8.1e-39 166.4 Lactobacillaceae Bacteria 1VWQW@1239,2E4BT@1,33YQ0@2,3FBRI@33958,4HWWB@91061 NA|NA|NA FFAGCILK_02427 543734.LCABL_16400 0.0 1228.8 Lactobacillaceae ysaB ko:K02004,ko:K19084 ko02010,ko02020,map02010,map02020 M00258,M00731,M00737 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.134 Bacteria 1TR2D@1239,3FBRY@33958,4H9SH@91061,COG0577@1,COG0577@2 NA|NA|NA V FtsX-like permease family FFAGCILK_02428 543734.LCABL_16410 6.3e-137 493.4 Lactobacillaceae XK27_05695 ko:K02003 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TNZG@1239,3F3MG@33958,4H9UT@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein FFAGCILK_02429 543734.LCABL_16420 8.8e-173 612.8 Lactobacillaceae Bacteria 1TSIC@1239,3F5QR@33958,4HFQK@91061,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor FFAGCILK_02430 543734.LCABL_16430 1.4e-122 445.7 Lactobacillaceae Bacteria 1TR32@1239,3FC95@33958,4HIBI@91061,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal FFAGCILK_02431 543734.LCABL_16440 9.8e-189 666.0 Lactobacillaceae ko:K08217 br01600,ko00000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.22 Bacteria 1UHRM@1239,3FBXB@33958,4ISTP@91061,COG0477@1,COG0477@2 NA|NA|NA EGP Transmembrane secretion effector FFAGCILK_02432 568703.LGG_01431 5.7e-49 200.3 Lactobacillaceae msi198 Bacteria 1UI3A@1239,3F83Y@33958,4ISBV@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain FFAGCILK_02433 543734.LCABL_16460 1.6e-64 251.9 Lactobacillaceae Bacteria 1UVU0@1239,3F7S8@33958,4IG71@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain FFAGCILK_02434 543734.LCABL_16470 9.2e-110 402.9 Bacilli nfnB GO:0000166,GO:0003674,GO:0003824,GO:0004155,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010181,GO:0016491,GO:0016645,GO:0016646,GO:0016651,GO:0016657,GO:0018545,GO:0018973,GO:0018974,GO:0019326,GO:0019439,GO:0032553,GO:0036094,GO:0042537,GO:0042802,GO:0043167,GO:0043168,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046256,GO:0046260,GO:0046263,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072490,GO:0072491,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 1.5.1.34 ko:K10679 ko00633,ko01120,map00633,map01120 R08014,R08017,R08042 RC00250 ko00000,ko00001,ko01000 iECUMN_1333.ECUMN_0668,iEcSMS35_1347.EcSMS35_0596,iJN746.PP_2432,iYO844.BSU07830 Bacteria 1UYJU@1239,4HYXD@91061,COG0778@1,COG0778@2 NA|NA|NA C Nitroreductase family FFAGCILK_02435 543734.LCABL_16480 1.1e-201 709.1 Lactobacillaceae hisC 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TPUV@1239,3F466@33958,4HA1H@91061,COG0079@1,COG0079@2 NA|NA|NA E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily FFAGCILK_02436 543734.LCABL_16490 2.1e-52 211.5 Lactobacillaceae hisE GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31,5.3.1.16 ko:K01523,ko:K01814,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037,R04640 RC00002,RC00945,RC01055 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS14110,iYO844.BSU34860 Bacteria 1VB6S@1239,3F7V5@33958,4HKDY@91061,COG0140@1,COG0140@2 NA|NA|NA E phosphoribosyl-ATP diphosphatase activity FFAGCILK_02437 543734.LCABL_16500 1.5e-58 231.9 Lactobacillaceae hisI GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.5.4.25,3.6.1.31,5.3.1.16 ko:K01496,ko:K01497,ko:K01814,ko:K11755 ko00340,ko00740,ko00790,ko01100,ko01110,ko01230,ko02024,map00340,map00740,map00790,map01100,map01110,map01230,map02024 M00026,M00125 R00425,R04035,R04037,R04640 RC00002,RC00293,RC00945,RC01055,RC02504 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_0880,iECW_1372.ECW_m2186,iEKO11_1354.EKO11_1768,iHN637.CLJU_RS05760,iSB619.SA_RS14110,iUMN146_1321.UM146_06665,iWFL_1372.ECW_m2186 Bacteria 1UYNA@1239,3F73W@33958,4HA9R@91061,COG0139@1,COG0139@2 NA|NA|NA E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP FFAGCILK_02438 543734.LCABL_16510 2.3e-131 474.9 Lactobacillaceae hisF GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 3.5.4.19,3.6.1.31 ko:K01663,ko:K02500,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037,R04558 RC00002,RC00010,RC01055,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 iECO111_1330.ECO111_2749,iEcolC_1368.EcolC_1617,iHN637.CLJU_RS05755,iLJ478.TM1036,iSB619.SA_RS14115,iYL1228.KPN_02481 Bacteria 1TP0W@1239,3F3XV@33958,4HAAM@91061,COG0107@1,COG0107@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit FFAGCILK_02439 543734.LCABL_16520 1.3e-123 449.1 Lactobacillaceae hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0388 Bacteria 1V1IR@1239,3F5YT@33958,4HACP@91061,COG0106@1,COG0106@2 NA|NA|NA E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase FFAGCILK_02440 543734.LCABL_16530 5.2e-113 413.7 Lactobacillaceae hisH ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQT0@1239,3FBCG@33958,4HHSP@91061,COG0118@1,COG0118@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR FFAGCILK_02441 543734.LCABL_16540 1.8e-104 385.2 Lactobacillaceae hisB GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,2.6.1.9,3.1.3.15,4.2.1.19 ko:K00013,ko:K00817,ko:K01089,ko:K01693 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R01158,R01163,R03012,R03013,R03243,R03457 RC00006,RC00017,RC00099,RC00242,RC00463,RC00888,RC00932 ko00000,ko00001,ko00002,ko01000,ko01007 iECO111_1330.ECO111_2746,iECS88_1305.ECS88_2121,iJN746.PP_0289,iLJ478.TM1039,iSB619.SA_RS14130,iUMNK88_1353.UMNK88_2570 Bacteria 1TRH7@1239,3F4TQ@33958,4HCFG@91061,COG0131@1,COG0131@2 NA|NA|NA E imidazoleglycerol-phosphate dehydratase FFAGCILK_02442 543734.LCABL_16550 1.3e-230 805.4 Lactobacillaceae hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,1.1.1.308 ko:K00013,ko:K15509 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPAW@1239,3F40P@33958,4H9XK@91061,COG0141@1,COG0141@2 NA|NA|NA E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine FFAGCILK_02443 543734.LCABL_16560 3.4e-112 411.0 Lactobacillaceae hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSVZ@1239,3F4WT@33958,4H9MH@91061,COG0040@1,COG0040@2 NA|NA|NA F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity FFAGCILK_02444 543734.LCABL_16570 4.9e-218 763.5 Lactobacillaceae hisZ 2.4.2.17,6.1.1.21 ko:K00765,ko:K01892,ko:K02502 ko00340,ko00970,ko01100,ko01110,ko01230,map00340,map00970,map01100,map01110,map01230 M00026,M00359,M00360 R01071,R03655 RC00055,RC00523,RC02819,RC03200 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPZZ@1239,3F4W1@33958,4HBBA@91061,COG3705@1,COG3705@2 NA|NA|NA E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine FFAGCILK_02445 543734.LCABL_16580 1.2e-205 722.2 Bacilli hisC 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TPUV@1239,4HA1H@91061,COG0079@1,COG0079@2 NA|NA|NA E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily FFAGCILK_02446 543734.LCABL_16600 5.8e-100 370.2 Lactobacillaceae 3.6.1.13 ko:K01515 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000 Bacteria 1VXC7@1239,3F45R@33958,4HX58@91061,COG0494@1,COG0494@2 NA|NA|NA L Belongs to the Nudix hydrolase family FFAGCILK_02447 543734.LCABL_16610 5.9e-160 570.1 Lactobacillaceae degV Bacteria 1TRM7@1239,3F40W@33958,4HBIR@91061,COG1307@1,COG1307@2 NA|NA|NA S EDD domain protein, DegV family FFAGCILK_02448 543734.LCABL_16620 0.0 1098.2 Lactobacillaceae FbpA ko:K12341 ko03070,map03070 ko00000,ko00001,ko02044 1.B.40.1.1 Bacteria 1TQ8A@1239,3F3PS@33958,4H9UF@91061,COG1293@1,COG1293@2 NA|NA|NA K Fibronectin-binding protein FFAGCILK_02449 543734.LCABL_16630 1.5e-49 201.8 Bacilli Bacteria 1VJNA@1239,4I1AJ@91061,COG1694@1,COG1694@2 NA|NA|NA S MazG-like family FFAGCILK_02450 543734.LCABL_16640 1.7e-194 685.3 Lactobacillaceae pfoS ko:K07035 ko00000 Bacteria 1TS5F@1239,3FCB4@33958,4HAK5@91061,COG3641@1,COG3641@2 NA|NA|NA S Phosphotransferase system, EIIC FFAGCILK_02451 543734.LCABL_16650 1.2e-177 629.0 Lactobacillaceae panE 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 Bacteria 1UM1M@1239,3FCCS@33958,4HBPD@91061,COG1893@1,COG1893@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid FFAGCILK_02452 543734.LCABL_16660 2.2e-206 724.9 Lactobacillaceae bfmBB 2.3.1.168,2.3.1.61 ko:K00658,ko:K09699 ko00020,ko00280,ko00310,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00280,map00310,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032,M00036 R02570,R02571,R02662,R03174,R04097,R08549,R10998 RC00004,RC02727,RC02833,RC02870 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1TQSH@1239,3F7YX@33958,4HBSU@91061,COG0508@1,COG0508@2 NA|NA|NA C 2-oxoacid dehydrogenases acyltransferase (catalytic domain) FFAGCILK_02453 543734.LCABL_16670 1.7e-182 645.2 Lactobacillaceae bfmBAB 1.2.4.1,1.2.4.4 ko:K00162,ko:K00167,ko:K21417 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00036,M00307 R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 iYO844.BSU24040 Bacteria 1TP3J@1239,3F4TD@33958,4HAP6@91061,COG0022@1,COG0022@2 NA|NA|NA C Transketolase, pyrimidine binding domain FFAGCILK_02454 543734.LCABL_16680 7.8e-188 662.9 Lactobacillaceae bfmBAA 1.2.4.4 ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS07640 Bacteria 1TQDG@1239,3F55B@33958,4HBEQ@91061,COG1071@1,COG1071@2 NA|NA|NA C Dehydrogenase E1 component FFAGCILK_02455 543734.LCABL_16690 2.7e-258 897.5 Lactobacillaceae lpdA GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0015036,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0016667,GO:0016668,GO:0019725,GO:0019899,GO:0032991,GO:0035375,GO:0036094,GO:0040007,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0045454,GO:0048037,GO:0050660,GO:0050662,GO:0050789,GO:0050794,GO:0051287,GO:0055114,GO:0065007,GO:0065008,GO:0070404,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TP1W@1239,3F5YW@33958,4H9Z5@91061,COG1249@1,COG1249@2 NA|NA|NA C 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FFAGCILK_02456 543734.LCABL_16700 3.6e-202 710.7 Lactobacillaceae buk 2.7.2.7 ko:K00929 ko00650,ko01100,map00650,map01100 R01688 RC00002,RC00043 ko00000,ko00001,ko01000 Bacteria 1TPKE@1239,3F6TG@33958,4H9QV@91061,COG3426@1,COG3426@2 NA|NA|NA C Acetokinase family FFAGCILK_02457 543734.LCABL_16710 1.5e-147 528.9 Lactobacillaceae pta 2.3.1.19,2.3.1.8 ko:K00625,ko:K00634,ko:K13788 ko00430,ko00620,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00650,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00230,R00921,R01174 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000 Bacteria 1TRQU@1239,3F7SC@33958,4HBSK@91061,COG0280@1,COG0280@2 NA|NA|NA C Phosphate acetyl/butaryl transferase FFAGCILK_02458 543734.LCABL_16720 1.8e-113 415.2 Lactobacillaceae pyrE 2.4.2.10,4.1.1.23 ko:K00762,ko:K01591,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00051 R00965,R01870,R08231 RC00063,RC00409,RC00611 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15560 Bacteria 1V1BZ@1239,3F487@33958,4HFV7@91061,COG0461@1,COG0461@2 NA|NA|NA F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) FFAGCILK_02459 543734.LCABL_16730 9.4e-127 459.5 Lactobacillaceae pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 iECO103_1326.ECO103_1444,iECSF_1327.ECSF_1264,iSFV_1184.SFV_1294,iSF_1195.SF1285,iSFxv_1172.SFxv_1457,iS_1188.S1368,ic_1306.c1750 Bacteria 1TPPH@1239,3F47Y@33958,4HAJ2@91061,COG0284@1,COG0284@2 NA|NA|NA F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) FFAGCILK_02460 543734.LCABL_16740 4.4e-155 553.9 Lactobacillaceae pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 ko:K00226,ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15540 Bacteria 1TPFV@1239,3F4PJ@33958,4HA5H@91061,COG0167@1,COG0167@2 NA|NA|NA F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily FFAGCILK_02461 543734.LCABL_16750 0.0 2057.0 Lactobacillaceae carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPID@1239,3F3MD@33958,4HAEY@91061,COG0458@1,COG0458@2 NA|NA|NA F Carbamoyl-phosphate synthase FFAGCILK_02462 543734.LCABL_16760 1.3e-209 735.3 Lactobacillaceae carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955,ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1383,iYO844.BSU15510 Bacteria 1TQ8N@1239,3F43R@33958,4H9Z0@91061,COG0505@1,COG0505@2 NA|NA|NA F Carbamoyl-phosphate synthetase glutamine chain FFAGCILK_02463 543734.LCABL_16770 8.8e-237 825.9 Lactobacillaceae pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPQM@1239,3F3S3@33958,4HA90@91061,COG0044@1,COG0044@2 NA|NA|NA F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily FFAGCILK_02464 543734.LCABL_16780 1.6e-179 635.2 Lactobacillaceae pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00608,ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15490 Bacteria 1TQ96@1239,3F4BQ@33958,4H9M6@91061,COG0540@1,COG0540@2 NA|NA|NA F Belongs to the ATCase OTCase family FFAGCILK_02465 543734.LCABL_16790 2.6e-236 824.3 Lactobacillaceae pyrP ko:K02824,ko:K16169 ko00000,ko02000 2.A.40.1.1,2.A.40.1.2,2.A.40.3.1 iLJ478.TM0819 Bacteria 1TQKX@1239,3F3UJ@33958,4HAEU@91061,COG2233@1,COG2233@2 NA|NA|NA F Permease FFAGCILK_02466 543734.LCABL_16800 1.7e-96 358.6 Lactobacillaceae pyrR GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000,ko03000 iHN637.CLJU_RS05275 Bacteria 1V3GV@1239,3F4SR@33958,4HGYE@91061,COG2065@1,COG2065@2 NA|NA|NA F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant FFAGCILK_02467 543734.LCABL_16810 1.4e-172 612.1 Lactobacillaceae rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 ko00000,ko01000,ko03009 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 1TPCM@1239,3F3P6@33958,4HBG2@91061,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil FFAGCILK_02468 543734.LCABL_16820 4.3e-80 303.9 Lactobacillaceae lspA 3.4.23.36 ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1VA9R@1239,3F66R@33958,4HIR4@91061,COG0597@1,COG0597@2 NA|NA|NA MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins FFAGCILK_02469 543734.LCABL_16830 0.0 1102.0 Lactobacillaceae fhs GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP6N@1239,3F3U6@33958,4HA2X@91061,COG2759@1,COG2759@2 NA|NA|NA F Belongs to the formate--tetrahydrofolate ligase family FFAGCILK_02470 1423732.BALS01000002_gene1011 1.7e-45 188.7 Lactobacillaceae Bacteria 1UUT0@1239,2BF1V@1,328TS@2,3F9TN@33958,4IHGJ@91061 NA|NA|NA S Family of unknown function (DUF5322) FFAGCILK_02471 543734.LCABL_16850 1.3e-69 268.9 Lactobacillaceae rnhA 3.1.26.4 ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1VH2B@1239,3F7JC@33958,4HIY9@91061,COG0328@1,COG0328@2 NA|NA|NA L Ribonuclease HI FFAGCILK_02472 543734.LCABL_16860 5.1e-110 403.7 Lactobacillaceae XK27_02070 ko:K07078 ko00000 Bacteria 1V1CR@1239,3F576@33958,4HD6W@91061,COG3560@1,COG3560@2 NA|NA|NA S Nitroreductase family FFAGCILK_02473 543734.LCABL_16880 2.6e-280 970.7 Lactobacillaceae cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0032502,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 ko:K06131 ko00564,ko01100,map00564,map01100 R07390 RC00017 ko00000,ko00001,ko01000 Bacteria 1TPKY@1239,3F3SF@33958,4H9TI@91061,COG1502@1,COG1502@2 NA|NA|NA I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol FFAGCILK_02474 568703.LGG_01471 1.8e-48 198.4 Lactobacillaceae Bacteria 1U6RT@1239,29PM1@1,30AJ7@2,3F8DQ@33958,4IGJ9@91061 NA|NA|NA FFAGCILK_02475 543734.LCABL_16900 9.3e-275 952.2 Bacilli Bacteria 1TVHZ@1239,2C9BC@1,2ZI2Q@2,4I07N@91061 NA|NA|NA S Mga helix-turn-helix domain FFAGCILK_02476 543734.LCABL_16910 2e-38 164.5 Lactobacillaceae nrdH GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009893,GO:0009987,GO:0016491,GO:0019222,GO:0019725,GO:0022900,GO:0042592,GO:0043085,GO:0044093,GO:0044237,GO:0045454,GO:0048518,GO:0050789,GO:0050790,GO:0050794,GO:0051341,GO:0051353,GO:0055114,GO:0065007,GO:0065008,GO:0065009 ko:K06191 ko00000 Bacteria 1VEFX@1239,3F874@33958,4HNUX@91061,COG0695@1,COG0695@2 NA|NA|NA O Glutaredoxin FFAGCILK_02477 543734.LCABL_16920 0.0 1457.6 Lactobacillaceae nrdE 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 iYO844.BSU17380 Bacteria 1TPFH@1239,3F3XG@33958,4H9X0@91061,COG0209@1,COG0209@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides FFAGCILK_02478 543734.LCABL_16930 2.4e-189 667.9 Lactobacillaceae nrdF 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1TQTH@1239,3F3P1@33958,4H9WX@91061,COG0208@1,COG0208@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides FFAGCILK_02479 543734.LCABL_16940 1.1e-161 575.9 Lactobacillaceae Bacteria 1TP77@1239,3F3VP@33958,4HAZB@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator FFAGCILK_02480 543734.LCABL_16950 0.0 1278.1 Lactobacillaceae pepO 3.4.24.71 ko:K01415,ko:K07386 ko00000,ko01000,ko01002,ko04147 Bacteria 1TQTA@1239,3F4CX@33958,4HDSF@91061,COG3590@1,COG3590@2 NA|NA|NA O Peptidase family M13 FFAGCILK_02481 543734.LCABL_16960 7.4e-194 682.9 Lactobacillaceae lplA 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 Bacteria 1TQ5U@1239,3F4UZ@33958,4H9P6@91061,COG0095@1,COG0095@2 NA|NA|NA H Lipoate-protein ligase FFAGCILK_02482 543734.LCABL_16970 3.9e-34 150.2 Lactobacillaceae Bacteria 1U71A@1239,2CDEF@1,30AS2@2,3F8UP@33958,4IGVR@91061 NA|NA|NA FFAGCILK_02483 543734.LCABL_16980 1.2e-174 619.0 Lactobacillaceae pdxB 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TSDK@1239,3F4DF@33958,4HAW5@91061,COG0111@1,COG0111@2 NA|NA|NA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FFAGCILK_02484 543734.LCABL_16990 2.2e-218 764.6 Lactobacillaceae rlmL GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016423,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 ko:K07444,ko:K12297 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 1TP0X@1239,3F3NZ@33958,4HBKY@91061,COG0116@1,COG0116@2 NA|NA|NA L Belongs to the methyltransferase superfamily FFAGCILK_02486 543734.LCABL_17000 2.3e-66 258.1 Lactobacillaceae gpsB ko:K04074 ko00000,ko03036 Bacteria 1VEQ4@1239,3F6VZ@33958,4HNP1@91061,COG3599@1,COG3599@2 NA|NA|NA D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation FFAGCILK_02487 543734.LCABL_17010 1.3e-107 395.6 Lactobacillaceae ypsA Bacteria 1V6SM@1239,3F4MR@33958,4HJGM@91061,COG4474@1,COG4474@2 NA|NA|NA S Belongs to the UPF0398 family FFAGCILK_02488 543734.LCABL_17020 5.1e-121 440.3 Lactobacillaceae recU GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 ko:K03700 ko00000,ko03400 Bacteria 1V3S4@1239,3F4DG@33958,4HGZ7@91061,COG3331@1,COG3331@2 NA|NA|NA L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation FFAGCILK_02489 543734.LCABL_17030 0.0 1350.1 Lactobacillaceae ponA GO:0005575,GO:0005576 2.4.1.129,3.4.16.4 ko:K03693,ko:K05365,ko:K05366,ko:K12555,ko:K21464 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 1TPM5@1239,3F424@33958,4H9SA@91061,COG0744@1,COG0744@2 NA|NA|NA M penicillin-binding protein 1A FFAGCILK_02490 543734.LCABL_17040 4.4e-85 320.5 Lactobacillaceae comEB 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 Bacteria 1V3PU@1239,3F6BF@33958,4HCDG@91061,COG2131@1,COG2131@2 NA|NA|NA F ComE operon protein 2 FFAGCILK_02491 543734.LCABL_17050 2.3e-114 418.3 Lactobacillaceae nth 4.2.99.18 ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TRAK@1239,3F42U@33958,4HATD@91061,COG0177@1,COG0177@2 NA|NA|NA L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate FFAGCILK_02492 543734.LCABL_17060 1.8e-113 415.2 Lactobacillaceae dnaD ko:K02086 ko00000 Bacteria 1V283@1239,3F4FF@33958,4HFP3@91061,COG3935@1,COG3935@2 NA|NA|NA L DnaD domain protein FFAGCILK_02493 543734.LCABL_17070 1.4e-258 898.3 Lactobacillaceae asnS GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP38@1239,3F4EK@33958,4H9YH@91061,COG0017@1,COG0017@2 NA|NA|NA J Asparaginyl-tRNA synthetase FFAGCILK_02494 543734.LCABL_17080 1e-218 765.8 Lactobacillaceae aspB GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052 RC00006,RC00025 ko00000,ko00001,ko01000,ko01007 iHN637.CLJU_RS06550 Bacteria 1TP0J@1239,3F3MX@33958,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase FFAGCILK_02495 543734.LCABL_17090 7.1e-86 323.2 Lactobacillaceae ypmB Bacteria 1VA2H@1239,3F4MM@33958,4HNMM@91061,COG5353@1,COG5353@2 NA|NA|NA S Protein conserved in bacteria FFAGCILK_02496 543734.LCABL_17100 0.0 1746.9 Lactobacillaceae dinG GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7,3.6.4.12 ko:K02342,ko:K03722 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TQHQ@1239,3F4KA@33958,4HB2Y@91061,COG0847@1,COG0847@2,COG1199@1,COG1199@2 NA|NA|NA L helicase involved in DNA repair and perhaps also replication FFAGCILK_02497 543734.LCABL_17110 0.0 2389.0 Lactobacillaceae addA 3.6.4.12 ko:K16898 ko00000,ko01000,ko03400 Bacteria 1TQ35@1239,3F3Z0@33958,4HA64@91061,COG1074@1,COG1074@2 NA|NA|NA L ATP-dependent helicase nuclease subunit A FFAGCILK_02498 543734.LCABL_17120 0.0 2310.4 Lactobacillaceae rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.3,3.6.4.12 ko:K01153,ko:K16899 ko00000,ko01000,ko02048,ko03400 Bacteria 1TQJW@1239,3F3RS@33958,4HAY6@91061,COG3857@1,COG3857@2 NA|NA|NA L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity FFAGCILK_02499 1423816.BACQ01000077_gene2640 4.9e-08 63.2 Bacilli lacC 2.7.1.11,2.7.1.144,2.7.1.56 ko:K00882,ko:K00917,ko:K16370 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00345 R00756,R02071,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR9H@1239,4HAGR@91061,COG1105@1,COG1105@2 NA|NA|NA H Belongs to the carbohydrate kinase PfkB family. LacC subfamily FFAGCILK_02500 543734.LCABL_17130 8.4e-168 596.3 Lactobacillaceae mvk 1.1.1.88,2.3.3.10,2.7.1.36 ko:K00054,ko:K00869,ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,ko04146,map00072,map00280,map00650,map00900,map01100,map01110,map01130,map04146 M00088,M00095 R01978,R02081,R02245 RC00002,RC00004,RC00017,RC00503,RC00644 ko00000,ko00001,ko00002,ko01000 Bacteria 1TT5C@1239,3F3TW@33958,4HAQQ@91061,COG1577@1,COG1577@2 NA|NA|NA I mevalonate kinase FFAGCILK_02501 543734.LCABL_17140 3.9e-179 634.0 Lactobacillaceae mvaD 4.1.1.33 ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R01121 RC00453 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQXR@1239,3F4B5@33958,4HAM6@91061,COG3407@1,COG3407@2 NA|NA|NA I diphosphomevalonate decarboxylase FFAGCILK_02502 543734.LCABL_17150 2.4e-192 677.9 Lactobacillaceae fni 1.1.1.88,5.3.3.2 ko:K00054,ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123,R02081 RC00004,RC00455,RC00644 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQZ3@1239,3F3UY@33958,4HAMV@91061,COG1304@1,COG1304@2 NA|NA|NA C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) FFAGCILK_02503 543734.LCABL_17160 2e-263 914.4 Lactobacillaceae rsmF 2.1.1.176 ko:K03500 ko00000,ko01000,ko03009 Bacteria 1TPGQ@1239,3F492@33958,4HCHQ@91061,COG0144@1,COG0144@2 NA|NA|NA J NOL1 NOP2 sun family protein FFAGCILK_02504 543734.LCABL_17170 2.7e-174 617.8 Lactobacillaceae Bacteria 1VNCY@1239,2EPHD@1,33H40@2,3F495@33958,4HYY7@91061 NA|NA|NA FFAGCILK_02505 543734.LCABL_17180 6.3e-142 510.0 Lactobacillaceae Bacteria 1VQQ8@1239,2E39Q@1,32Y99@2,3F4UX@33958,4HRY1@91061 NA|NA|NA FFAGCILK_02506 543734.LCABL_17190 8.2e-60 236.1 Lactobacillaceae yitW ko:K02612 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 1V9YV@1239,3F7D5@33958,4HKC6@91061,COG2151@1,COG2151@2 NA|NA|NA S Iron-sulfur cluster assembly protein FFAGCILK_02507 543734.LCABL_17200 7.9e-25 119.0 Lactobacillaceae dmpI GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 Bacteria 1VKD5@1239,3F83T@33958,4HRBS@91061,COG1942@1,COG1942@2 NA|NA|NA G Belongs to the 4-oxalocrotonate tautomerase family FFAGCILK_02508 543734.LCABL_17210 6e-151 540.0 Lactobacillaceae yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.4.16 ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ27@1239,3F3ZD@33958,4H9NY@91061,COG0327@1,COG0327@2 NA|NA|NA S Belongs to the GTP cyclohydrolase I type 2 NIF3 family FFAGCILK_02509 543734.LCABL_17220 1.8e-125 455.3 Lactobacillaceae trmK GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.217 ko:K06967 ko00000,ko01000,ko03016 Bacteria 1V3I4@1239,3F4GT@33958,4HHIM@91061,COG2384@1,COG2384@2 NA|NA|NA S SAM-dependent methyltransferase FFAGCILK_02510 543734.LCABL_17240 3.4e-188 664.5 Lactobacillaceae sigA GO:0000988,GO:0000990,GO:0001098,GO:0001101,GO:0001108,GO:0001666,GO:0002791,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0016020,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032879,GO:0032880,GO:0036293,GO:0040007,GO:0042221,GO:0043175,GO:0043254,GO:0044087,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051173,GO:0051223,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070063,GO:0070201,GO:0070482,GO:0071944,GO:0080090,GO:0090087,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:1903530,GO:2000112,GO:2000142,GO:2001141 ko:K03086,ko:K03087 ko02026,ko05111,map02026,map05111 ko00000,ko00001,ko03021 Bacteria 1TPD6@1239,3F4CF@33958,4HB1H@91061,COG0568@1,COG0568@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth FFAGCILK_02511 543734.LCABL_17250 0.0 1125.5 Lactobacillaceae dnaG ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1TQ0X@1239,3F3N1@33958,4HAG2@91061,COG0358@1,COG0358@2 NA|NA|NA L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication FFAGCILK_02512 543734.LCABL_17260 0.0 1316.6 Lactobacillaceae glyS GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 ko:K01879,ko:K14164 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAPECO1_1312.APECO1_2891,iE2348C_1286.E2348C_3810,iECABU_c1320.ECABU_c40010,iECED1_1282.ECED1_4242,iECH74115_1262.ECH74115_4934,iECNA114_1301.ECNA114_3710,iECOK1_1307.ECOK1_4005,iECP_1309.ECP_3661,iECS88_1305.ECS88_3976,iECSF_1327.ECSF_3393,iECSP_1301.ECSP_4554,iECs_1301.ECs4442,iG2583_1286.G2583_4300,iJN678.glyS,iUMN146_1321.UM146_17960,iUTI89_1310.UTI89_C4099,ic_1306.c4378 Bacteria 1TNZ7@1239,3F4G8@33958,4H9NT@91061,COG0751@1,COG0751@2 NA|NA|NA J Glycyl-tRNA synthetase beta subunit FFAGCILK_02513 568703.LGG_01514 2e-171 608.2 Lactobacillaceae glyQ GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016875,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 ko:K01878,ko:K14164 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF1260.b3560,iAF987.Gmet_2942,iJO1366.b3560,iPC815.YPO4072,iY75_1357.Y75_RS19360 Bacteria 1TPW8@1239,3F3T8@33958,4HBCF@91061,COG0752@1,COG0752@2 NA|NA|NA J glycyl-tRNA synthetase alpha subunit FFAGCILK_02514 543734.LCABL_17280 5.8e-41 173.3 Lactobacillaceae Bacteria 1VZDC@1239,2C8G2@1,348DR@2,3F740@33958,4HZ47@91061 NA|NA|NA FFAGCILK_02515 543734.LCABL_17290 2.3e-53 214.5 Lactobacillaceae Bacteria 1VZDC@1239,2C8G2@1,348DR@2,3F740@33958,4HZ47@91061 NA|NA|NA FFAGCILK_02516 543734.LCABL_17300 3.3e-141 507.7 Lactobacillaceae recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1UZ19@1239,3F56P@33958,4HAHI@91061,COG1381@1,COG1381@2 NA|NA|NA L Involved in DNA repair and RecF pathway recombination FFAGCILK_02517 543734.LCABL_17310 1.4e-167 595.5 Lactobacillaceae era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 ko:K03595,ko:K06883 ko00000,ko03009,ko03029 Bacteria 1TP3R@1239,3F3WQ@33958,4H9WF@91061,COG1159@1,COG1159@2 NA|NA|NA S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism FFAGCILK_02518 543734.LCABL_17320 8e-64 249.6 Lactobacillaceae cdd GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006216,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009116,GO:0009119,GO:0009164,GO:0009972,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042454,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 2.4.2.2,3.5.4.5 ko:K00756,ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01570,R01876,R01878,R02296,R02484,R02485,R08221 RC00063,RC00074,RC00514 ko00000,ko00001,ko01000 iSB619.SA_RS07895,iYO844.BSU25300 Bacteria 1V6IP@1239,3F7RM@33958,4HIJ3@91061,COG0295@1,COG0295@2 NA|NA|NA F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis FFAGCILK_02519 543734.LCABL_17330 3.1e-63 247.7 Lactobacillaceae dgkA 2.7.1.107,2.7.1.66 ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 R02240,R05626 RC00002,RC00017 ko00000,ko00001,ko01000 iAF987.Gmet_2369,iSB619.SA_RS07900 Bacteria 1VEGR@1239,3F7DC@33958,4HNKN@91061,COG0818@1,COG0818@2 NA|NA|NA M Diacylglycerol kinase FFAGCILK_02520 543734.LCABL_17340 2e-82 311.6 Lactobacillaceae ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 ko:K01489,ko:K03474,ko:K03595,ko:K07042 ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100 M00124 R01878,R02485,R05838,R08221 RC00074,RC00514,RC01476 ko00000,ko00001,ko00002,ko01000,ko03009,ko03029 Bacteria 1V6BU@1239,3F516@33958,4HIIE@91061,COG0319@1,COG0319@2 NA|NA|NA S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA FFAGCILK_02521 543734.LCABL_17350 5.9e-180 636.7 Lactobacillaceae phoH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06217 ko00000 Bacteria 1TP35@1239,3F4E7@33958,4HBD5@91061,COG1702@1,COG1702@2 NA|NA|NA T phosphate starvation-inducible protein PhoH FFAGCILK_02523 543734.LCABL_17360 6.1e-68 263.5 Lactobacillaceae yqeY ko:K09117 ko00000 Bacteria 1V6F2@1239,3F6I0@33958,4HIQP@91061,COG1610@1,COG1610@2 NA|NA|NA S YqeY-like protein FFAGCILK_02524 543734.LCABL_17370 2.9e-21 107.1 Lactobacillaceae rpsU GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02970 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEHU@1239,3F81Y@33958,4HNPV@91061,COG0828@1,COG0828@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS21 family FFAGCILK_02525 543734.LCABL_17380 2.7e-154 551.2 Lactobacillaceae yqfL 2.7.11.33,2.7.4.28 ko:K09773 ko00000,ko01000 Bacteria 1TPG0@1239,3F3WK@33958,4HB0Q@91061,COG1806@1,COG1806@2 NA|NA|NA F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation FFAGCILK_02526 543734.LCABL_17390 3.8e-162 577.4 Lactobacillaceae nfo GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TP1D@1239,3F42I@33958,4HB4F@91061,COG0648@1,COG0648@2 NA|NA|NA L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin FFAGCILK_02527 543734.LCABL_17400 7.4e-169 599.7 Lactobacillaceae yitT Bacteria 1TRBT@1239,3F3PH@33958,4HBPR@91061,COG1284@1,COG1284@2 NA|NA|NA S Uncharacterised 5xTM membrane BCR, YitT family COG1284 FFAGCILK_02528 543734.LCABL_17410 1.3e-81 308.9 Lactobacillaceae msrB 1.8.4.11,1.8.4.12 ko:K07305,ko:K12267 ko00000,ko01000 Bacteria 1UPN0@1239,3F6H4@33958,4HGWN@91061,COG0229@1,COG0229@2 NA|NA|NA O peptide methionine sulfoxide reductase FFAGCILK_02529 543734.LCABL_17420 0.0 1211.4 Lactobacillaceae aspS 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TPCN@1239,3F4PE@33958,4HACD@91061,COG0173@1,COG0173@2 NA|NA|NA J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) FFAGCILK_02530 543734.LCABL_17430 1.5e-244 851.7 Lactobacillaceae hisS 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP3D@1239,3F3M3@33958,4HAM2@91061,COG0124@1,COG0124@2 NA|NA|NA J histidyl-tRNA synthetase FFAGCILK_02531 543734.LCABL_17440 1.7e-35 155.2 Lactobacillaceae XK27_04345 3.6.1.1 ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 1VB6Q@1239,3F81A@33958,4HKI4@91061,COG0221@1,COG0221@2 NA|NA|NA C Inorganic pyrophosphatase FFAGCILK_02532 543734.LCABL_17450 1.3e-82 312.4 Lactobacillaceae 1.6.5.5 ko:K00344 ko00000,ko01000 Bacteria 1VZMF@1239,3F5Z3@33958,4HY0D@91061,COG0604@1,COG0604@2 NA|NA|NA C nadph quinone reductase FFAGCILK_02533 543734.LCABL_17480 2.8e-274 950.7 Lactobacillaceae Bacteria 1VUTX@1239,2DV5N@1,33U6G@2,3FBQP@33958,4HVQT@91061 NA|NA|NA FFAGCILK_02534 543734.LCABL_17490 1.6e-157 562.0 Lactobacillaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TRJH@1239,3F52V@33958,4HFS1@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter FFAGCILK_02535 543734.LCABL_17500 1.1e-82 312.4 Lactobacillaceae Bacteria 1V5XZ@1239,3FCAY@33958,4HHN5@91061,COG0537@1,COG0537@2 NA|NA|NA FG adenosine 5'-monophosphoramidase activity FFAGCILK_02536 543734.LCABL_17510 7.8e-244 849.4 Lactobacillaceae lytH GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28,6.1.1.12 ko:K01448,ko:K01876,ko:K21472 ko00970,ko01503,map00970,map01503 M00359,M00360,M00727 R04112,R05577 RC00055,RC00064,RC00141,RC00523 ko00000,ko00001,ko00002,ko01000,ko01002,ko01007,ko01011,ko03016,ko03029,ko03036 Bacteria 1UYPW@1239,3F4F4@33958,4HBVT@91061,COG0860@1,COG0860@2,COG3807@1,COG3807@2 NA|NA|NA M N-acetylmuramoyl-L-alanine amidase FFAGCILK_02537 543734.LCABL_17520 2.6e-117 427.9 Lactobacillaceae 3.1.3.18 ko:K01091,ko:K07025 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 R01334 RC00017 ko00000,ko00001,ko01000 Bacteria 1V3DR@1239,3F741@33958,4HGMU@91061,COG0546@1,COG0546@2 NA|NA|NA J HAD-hyrolase-like FFAGCILK_02538 543734.LCABL_17530 4.2e-77 293.9 Lactobacillaceae dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360 ko:K07560 ko00000,ko01000,ko03016 Bacteria 1V6GH@1239,3F6GK@33958,4HINN@91061,COG1490@1,COG1490@2 NA|NA|NA J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality FFAGCILK_02539 543734.LCABL_17540 0.0 1479.9 Lactobacillaceae relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 R00429 RC00002,RC00078 ko00000,ko00001,ko01000 iHN637.CLJU_RS16615,iYO844.BSU27600 Bacteria 1TNYZ@1239,3F44F@33958,4HBX7@91061,COG0317@1,COG0317@2 NA|NA|NA KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance FFAGCILK_02540 1423732.BALS01000048_gene2576 1.3e-43 182.2 Lactobacillaceae Bacteria 1U70F@1239,2DKTI@1,30ARB@2,3F8T9@33958,4IGUR@91061 NA|NA|NA FFAGCILK_02541 543734.LCABL_17560 1.3e-131 475.7 Lactobacillaceae rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 ko00000,ko01000,ko03009 Bacteria 1V1CT@1239,3F64Z@33958,4HH8P@91061,COG1385@1,COG1385@2 NA|NA|NA J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit FFAGCILK_02542 543734.LCABL_17570 2.3e-173 614.8 Lactobacillaceae prmA ko:K02687 ko00000,ko01000,ko03009 Bacteria 1TPKI@1239,3F47Z@33958,4HAMF@91061,COG2264@1,COG2264@2 NA|NA|NA J Ribosomal protein L11 methyltransferase FFAGCILK_02543 543734.LCABL_17580 2.9e-87 327.8 Lactobacillaceae XK27_03960 Bacteria 1VFZQ@1239,2E0MY@1,32W75@2,3F6FP@33958,4HKWR@91061 NA|NA|NA S Protein of unknown function (DUF3013) FFAGCILK_02544 543734.LCABL_17590 6.2e-111 406.8 Lactobacillaceae mpg GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1V1E6@1239,3FC7N@33958,4HJ10@91061,COG2094@1,COG2094@2 NA|NA|NA L Belongs to the DNA glycosylase MPG family FFAGCILK_02545 543734.LCABL_17600 5.3e-37 159.8 Lactobacillaceae Bacteria 1U7TK@1239,29QBB@1,30BAI@2,3FA5R@33958,4IHR2@91061 NA|NA|NA FFAGCILK_02546 543734.LCABL_17610 3.8e-66 257.3 Lactobacillaceae Bacteria 1W0J9@1239,3F8AZ@33958,4HYK1@91061,COG5294@1,COG5294@2 NA|NA|NA S Protein of unknown function (DUF1093) FFAGCILK_02547 568703.LGG_00464 1e-178 632.5 Lactobacillaceae Bacteria 1TRSF@1239,3F3WY@33958,4HTRR@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family FFAGCILK_02548 862514.HMPREF0623_1556 2.5e-56 226.1 Bacilli XK27_02965 Bacteria 1VPXY@1239,4HS1S@91061,COG1835@1,COG1835@2 NA|NA|NA I Acyltransferase family FFAGCILK_02549 1158609.I586_01142 5.5e-103 381.7 Enterococcaceae Bacteria 1TZ29@1239,4B21E@81852,4I895@91061,COG1807@1,COG1807@2 NA|NA|NA M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family FFAGCILK_02550 543734.LCABL_20250 1.1e-100 373.6 Lactobacillaceae Bacteria 1V0GX@1239,3F4TH@33958,4HCXH@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase FFAGCILK_02551 568703.LGG_01577 4.8e-19 99.8 Lactobacillaceae Bacteria 1U7XK@1239,29QDN@1,30BCY@2,3FAAQ@33958,4IHUZ@91061 NA|NA|NA FFAGCILK_02552 568703.LGG_01578 1.2e-48 199.1 Lactobacillaceae Bacteria 1U6BX@1239,29PAD@1,30A8I@2,3F7JN@33958,4IG3I@91061 NA|NA|NA FFAGCILK_02554 1423816.BACQ01000058_gene2233 7.3e-74 285.0 Bacteria ko:K20999 ko02025,map02025 ko00000,ko00001,ko01003 GT4 Bacteria COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups FFAGCILK_02555 568703.LGG_01582 6.3e-121 440.7 Lactobacillaceae mocA ko:K22230 ko00562,ko01120,map00562,map01120 R09954 RC00182 ko00000,ko00001,ko01000 Bacteria 1TQSS@1239,3F4EV@33958,4HCIG@91061,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase FFAGCILK_02556 568703.LGG_00349 1e-269 935.6 Lactobacillaceae 2.4.1.52 ko:K00712 ko00000,ko01000,ko01003 GT4 Bacteria 1TR6K@1239,3F4P6@33958,4HGDG@91061,COG0438@1,COG0438@2 NA|NA|NA M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon FFAGCILK_02557 568703.LGG_01587 2.9e-250 870.9 Lactobacillaceae 2.4.1.52 ko:K00712 ko00000,ko01000,ko01003 GT4 Bacteria 1UY71@1239,3FC1Q@33958,4HFBM@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 FFAGCILK_02560 568703.LGG_01589 8.8e-155 553.9 Bacteria 2.4.1.9,3.4.24.40 ko:K01406,ko:K20811 ko00500,ko01503,map00500,map01503 R04194 RC00077,RC00247 ko00000,ko00001,ko01000,ko01002 GH68 Bacteria COG2340@1,COG2340@2,COG4932@1,COG4932@2 NA|NA|NA S peptidase inhibitor activity FFAGCILK_02562 568703.LGG_01591 4.4e-177 628.6 Lactobacillaceae Bacteria 1U7FA@1239,29Q3U@1,30B2I@2,3F9IU@33958,4IHBA@91061 NA|NA|NA FFAGCILK_02563 568703.LGG_01592 2.4e-77 298.9 Lactobacillaceae Bacteria 1VR35@1239,2DQAU@1,335PW@2,3F7WX@33958,4HUUM@91061 NA|NA|NA FFAGCILK_02564 568703.LGG_01593 2.6e-98 365.5 Lactobacillaceae Bacteria 1U7GD@1239,29Q4I@1,30B38@2,3F9M4@33958,4IHCJ@91061 NA|NA|NA FFAGCILK_02565 543734.LCABL_17680 1.4e-147 528.9 Lactobacillaceae hutG 3.5.3.8 ko:K01479 ko00340,ko01100,map00340,map01100 M00045 R02285 RC00221,RC00681 ko00000,ko00001,ko00002,ko01000 Bacteria 1V6B3@1239,3F6V6@33958,4HQ4E@91061,COG3741@1,COG3741@2 NA|NA|NA E N-formylglutamate amidohydrolase FFAGCILK_02566 543734.LCABL_17690 7.9e-54 216.1 Lactobacillaceae XK27_08430 Bacteria 1VIJK@1239,2ED3T@1,3370N@2,3F765@33958,4HPGM@91061 NA|NA|NA S Staphylococcal protein of unknown function (DUF960) FFAGCILK_02567 543734.LCABL_17700 2.9e-90 337.8 Lactobacillaceae ybaK ko:K03976 ko00000,ko01000,ko03016 Bacteria 1V6JF@1239,3F5H1@33958,4HHVB@91061,COG2606@1,COG2606@2 NA|NA|NA S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily FFAGCILK_02568 543734.LCABL_17710 5.3e-95 353.6 Lactobacillaceae apt GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.22,2.4.2.7 ko:K00759,ko:K03816,ko:K09685 ko00230,ko01100,ko01110,map00230,map01100,map01110 R00190,R01229,R02142,R04378 RC00063,RC00122 ko00000,ko00001,ko01000,ko03000,ko04147 Bacteria 1V1BV@1239,3F4DB@33958,4HFUA@91061,COG0503@1,COG0503@2 NA|NA|NA F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis FFAGCILK_02569 543734.LCABL_17720 0.0 1482.2 Lactobacillaceae recJ ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPXE@1239,3F42C@33958,4H9UP@91061,COG0608@1,COG0608@2 NA|NA|NA L Single-stranded-DNA-specific exonuclease RecJ FFAGCILK_02570 1423816.BACQ01000009_gene264 1.5e-56 225.3 Lactobacillaceae Bacteria 1U6KN@1239,29PHG@1,30AFM@2,3F83U@33958,4IGDE@91061 NA|NA|NA FFAGCILK_02571 543734.LCABL_17740 2.1e-82 311.6 Lactobacillaceae 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 R02301 RC00183 ko00000,ko00001,ko01000 Bacteria 1V6S0@1239,3F7EV@33958,4HKKR@91061,COG4405@1,COG4405@2 NA|NA|NA S ASCH FFAGCILK_02572 1423816.BACQ01000009_gene262 4.9e-24 116.7 Lactobacillaceae Bacteria 1U7VD@1239,2AI13@1,318EQ@2,3FA82@33958,4IHST@91061 NA|NA|NA FFAGCILK_02573 543734.LCABL_17760 0.0 1190.6 Lactobacillaceae lepA ko:K03596 ko05134,map05134 ko00000,ko00001 Bacteria 1TP0G@1239,3F3Z1@33958,4HASA@91061,COG0481@1,COG0481@2 NA|NA|NA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner FFAGCILK_02574 1231336.L248_1955 1.6e-51 209.9 Lactobacillaceae Bacteria 1V9XM@1239,3F79A@33958,4HJUU@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins FFAGCILK_02575 1231336.L248_1956 6.5e-144 517.7 Lactobacillaceae ko:K06147,ko:K06148 ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TSRV@1239,3F4EQ@33958,4HCIZ@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter transmembrane region FFAGCILK_02576 543734.LCABL_17770 3.6e-192 677.6 Lactobacillaceae dnaJ ko:K03686 ko00000,ko03029,ko03110 Bacteria 1TP00@1239,3F490@33958,4H9KA@91061,COG0484@1,COG0484@2 NA|NA|NA O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins FFAGCILK_02577 543734.LCABL_17780 9.7e-309 1065.4 Lactobacillaceae dnaK GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065 ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 Bacteria 1TP1J@1239,3F48C@33958,4HA9S@91061,COG0443@1,COG0443@2 NA|NA|NA O Heat shock 70 kDa protein FFAGCILK_02578 543734.LCABL_17790 3.4e-98 364.4 Lactobacillaceae grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009628,GO:0009986,GO:0009987,GO:0009991,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030246,GO:0030247,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071496,GO:0071840,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 ko:K03687 ko00000,ko03029,ko03110 Bacteria 1V6G2@1239,3F4DY@33958,4HIRK@91061,COG0576@1,COG0576@2 NA|NA|NA O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ FFAGCILK_02579 543734.LCABL_17800 1.4e-192 678.7 Lactobacillaceae hrcA GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K03705 ko00000,ko03000 Bacteria 1TQP7@1239,3F3ST@33958,4HAX5@91061,COG1420@1,COG1420@2 NA|NA|NA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons FFAGCILK_02580 543734.LCABL_17810 2e-224 784.6 Lactobacillaceae hemN Bacteria 1TPES@1239,3F4BA@33958,4HA60@91061,COG0635@1,COG0635@2 NA|NA|NA H Involved in the biosynthesis of porphyrin-containing compound FFAGCILK_02581 543734.LCABL_17820 2.7e-174 617.8 Lactobacillaceae ribF 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS06310 Bacteria 1TPKS@1239,3F3TG@33958,4H9KE@91061,COG0196@1,COG0196@2 NA|NA|NA H Belongs to the ribF family FFAGCILK_02582 543734.LCABL_17830 2e-166 591.7 Lactobacillaceae truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177,ko:K03483 ko00000,ko01000,ko03000,ko03016 iSB619.SA_RS06305 Bacteria 1TP9Y@1239,3F3NX@33958,4HA9X@91061,COG0130@1,COG0130@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs FFAGCILK_02583 543734.LCABL_17840 8.5e-143 513.5 Lactobacillaceae terC ko:K05794 ko00000 Bacteria 1TQ09@1239,3FB68@33958,4HB99@91061,COG0861@1,COG0861@2 NA|NA|NA P Integral membrane protein TerC family FFAGCILK_02584 1423732.BALS01000003_gene941 4.6e-58 230.3 Lactobacillaceae rbfA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 ko:K02834 ko00000,ko03009 Bacteria 1VA0P@1239,3F6WZ@33958,4HII1@91061,COG0858@1,COG0858@2 NA|NA|NA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA FFAGCILK_02585 543734.LCABL_17860 0.0 1327.4 Lactobacillaceae infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K02519 ko00000,ko03012,ko03029 Bacteria 1TPAI@1239,3F3JV@33958,4HA8S@91061,COG0532@1,COG0532@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex FFAGCILK_02586 543734.LCABL_17870 6.5e-45 186.4 Lactobacillaceae ylxQ ko:K07590,ko:K07742 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEYG@1239,3F7ZK@33958,4HNY7@91061,COG1358@1,COG1358@2 NA|NA|NA J ribosomal protein FFAGCILK_02587 543734.LCABL_17880 1.7e-45 188.3 Lactobacillaceae ylxR ko:K02600,ko:K07742 ko00000,ko03009,ko03021 Bacteria 1VEJS@1239,3F7E2@33958,4HKBY@91061,COG2740@1,COG2740@2 NA|NA|NA K Protein of unknown function (DUF448) FFAGCILK_02588 543734.LCABL_17890 6.3e-195 686.8 Lactobacillaceae nusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K02600,ko:K02945 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03009,ko03011,ko03021 Bacteria 1TPB3@1239,3F3KZ@33958,4HA7F@91061,COG0195@1,COG0195@2 NA|NA|NA K Participates in both transcription termination and antitermination FFAGCILK_02589 543734.LCABL_17900 1.7e-84 318.5 Lactobacillaceae rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 ko:K09748 ko00000,ko03009 Bacteria 1V6KT@1239,3F6GZ@33958,4HH88@91061,COG0779@1,COG0779@2 NA|NA|NA J Required for maturation of 30S ribosomal subunits FFAGCILK_02590 543734.LCABL_17910 0.0 2870.5 Lactobacillaceae polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K02342,ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TPAG@1239,3F4AN@33958,4H9RF@91061,COG2176@1,COG2176@2 NA|NA|NA L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity FFAGCILK_02591 543734.LCABL_17920 0.0 1114.8 Lactobacillaceae proS GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iJN678.proS,iUTI89_1310.UTI89_C0210 Bacteria 1TRBV@1239,3F44A@33958,4H9NN@91061,COG0442@1,COG0442@2 NA|NA|NA J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS FFAGCILK_02592 543734.LCABL_17930 1.4e-231 808.5 Lactobacillaceae rseP GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0040007,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 3.4.21.107,3.4.21.116 ko:K04771,ko:K06399,ko:K11749,ko:K16922 ko01503,ko02020,ko02024,ko04112,map01503,map02020,map02024,map04112 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1TPMC@1239,3F3TM@33958,4HAQ5@91061,COG0750@1,COG0750@2 NA|NA|NA M zinc metalloprotease FFAGCILK_02593 543734.LCABL_17940 1.2e-138 499.2 Lactobacillaceae cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS06255 Bacteria 1TT0Q@1239,3FC0H@33958,4HAMN@91061,COG4589@1,COG4589@2 NA|NA|NA S Belongs to the CDS family FFAGCILK_02594 543734.LCABL_17950 5e-139 500.4 Lactobacillaceae uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 Bacteria 1TQTS@1239,3F42M@33958,4HA37@91061,COG0020@1,COG0020@2 NA|NA|NA H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids FFAGCILK_02595 543734.LCABL_17960 1.8e-93 348.6 Lactobacillaceae frr GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02838 ko00000,ko03012 Bacteria 1V1F2@1239,3F4X2@33958,4HFSH@91061,COG0233@1,COG0233@2 NA|NA|NA J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another FFAGCILK_02596 543734.LCABL_17970 5.9e-129 466.8 Lactobacillaceae pyrH GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 R00158 RC00002 ko00000,ko00001,ko01000 iSB619.SA_RS06240 Bacteria 1TPXN@1239,3F42J@33958,4H9UB@91061,COG0528@1,COG0528@2 NA|NA|NA F Catalyzes the reversible phosphorylation of UMP to UDP FFAGCILK_02597 543734.LCABL_17980 5.3e-156 557.0 Lactobacillaceae tsf GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 ko:K02357 ko00000,ko03012,ko03029 Bacteria 1TPFJ@1239,3F459@33958,4HBDV@91061,COG0264@1,COG0264@2 NA|NA|NA J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome FFAGCILK_02598 543734.LCABL_17990 1e-142 512.7 Lactobacillaceae rpsB GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02967 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPNA@1239,3F3M1@33958,4H9N5@91061,COG0052@1,COG0052@2 NA|NA|NA J Belongs to the universal ribosomal protein uS2 family FFAGCILK_02599 543734.LCABL_18000 1.5e-45 188.3 Lactobacillaceae yazA ko:K07461 ko00000 Bacteria 1VEZF@1239,3F7G2@33958,4HNHJ@91061,COG2827@1,COG2827@2 NA|NA|NA L GIY-YIG catalytic domain protein FFAGCILK_02600 543734.LCABL_18010 2.7e-129 468.0 Lactobacillaceae yabB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.223 ko:K07461,ko:K15460 ko00000,ko01000,ko03016 Bacteria 1TQ25@1239,3F4C5@33958,4HA8W@91061,COG4123@1,COG4123@2 NA|NA|NA L Methyltransferase small domain FFAGCILK_02601 543734.LCABL_18020 2.6e-123 448.0 Lactobacillaceae plsC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008374,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0042171,GO:0044464,GO:0071617,GO:0071944 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1U8N2@1239,3F4QB@33958,4HDQR@91061,COG0204@1,COG0204@2 NA|NA|NA I Acyltransferase FFAGCILK_02602 543734.LCABL_18030 1.9e-216 758.4 Lactobacillaceae yfnA ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ4K@1239,3F3QY@33958,4HA66@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino Acid FFAGCILK_02603 543734.LCABL_18040 6.7e-142 510.0 Lactobacillaceae yejC Bacteria 1V46X@1239,3F4FJ@33958,4HI49@91061,COG4420@1,COG4420@2 NA|NA|NA S Protein of unknown function (DUF1003) FFAGCILK_02604 543734.LCABL_18050 0.0 1140.2 Lactobacillaceae mdlB GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008144,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0031224,GO:0032553,GO:0032555,GO:0032559,GO:0033036,GO:0034040,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K06147,ko:K18890 ko02010,map02010 M00707 ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,3F3PD@33958,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter FFAGCILK_02605 543734.LCABL_18060 0.0 1138.3 Lactobacillaceae mdlA GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016021,GO:0017076,GO:0030554,GO:0031224,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K06148,ko:K18889 ko02010,map02010 M00707 ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 Bacteria 1TP0B@1239,3F3PD@33958,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter FFAGCILK_02606 543734.LCABL_18070 4.8e-29 133.3 Lactobacillaceae yneF ko:K09976 ko00000 Bacteria 1VEJC@1239,3FCDQ@33958,4HNN9@91061,COG3763@1,COG3763@2 NA|NA|NA S UPF0154 protein FFAGCILK_02607 543734.LCABL_18080 4e-37 160.2 Lactobacillaceae ynzC Bacteria 1VEKJ@1239,3F87S@33958,4HNIB@91061,COG4224@1,COG4224@2 NA|NA|NA S UPF0291 protein FFAGCILK_02608 568703.LGG_01638 9.4e-20 102.1 Lactobacillaceae Bacteria 1U7XM@1239,29QDP@1,30BCZ@2,3FAAR@33958,4IHV0@91061 NA|NA|NA FFAGCILK_02609 543734.LCABL_18100 2.9e-57 227.6 Lactobacillaceae rplS GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02884 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6FT@1239,3F6K4@33958,4HIK3@91061,COG0335@1,COG0335@2 NA|NA|NA J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site FFAGCILK_02610 543734.LCABL_18110 5.3e-144 516.9 Lactobacillaceae trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 ko:K00554,ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 1TPBV@1239,3F3NP@33958,4HBFV@91061,COG0336@1,COG0336@2 NA|NA|NA J Belongs to the RNA methyltransferase TrmD family FFAGCILK_02611 543734.LCABL_18120 2.2e-93 348.2 Lactobacillaceae rimM GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 ko:K02860 ko00000,ko03009 Bacteria 1V6HD@1239,3F74P@33958,4HH3H@91061,COG0806@1,COG0806@2 NA|NA|NA J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes FFAGCILK_02612 543734.LCABL_18140 2.2e-38 164.5 Lactobacillaceae ylqC ko:K06960 ko00000 Bacteria 1VEG7@1239,3F829@33958,4HNX0@91061,COG1837@1,COG1837@2 NA|NA|NA S Belongs to the UPF0109 family FFAGCILK_02613 543734.LCABL_18150 1e-44 185.7 Lactobacillaceae rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02959 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1VA0X@1239,3F6VV@33958,4HKNN@91061,COG0228@1,COG0228@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS16 family FFAGCILK_02614 543734.LCABL_18160 6.3e-231 806.6 Lactobacillaceae ffh GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 Bacteria 1TP06@1239,3F40R@33958,4H9T4@91061,COG0541@1,COG0541@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY FFAGCILK_02615 543734.LCABL_18170 3.8e-57 227.3 Lactobacillaceae ylxM GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772 ko:K09787 ko00000 Bacteria 1VEGP@1239,3F7FG@33958,4HKK6@91061,COG2739@1,COG2739@2 NA|NA|NA S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein FFAGCILK_02616 543734.LCABL_18180 8.8e-53 212.6 Lactobacillaceae Bacteria 1VPSM@1239,2EU16@1,33MI8@2,3F6QA@33958,4HS7T@91061 NA|NA|NA FFAGCILK_02617 543734.LCABL_18190 1.6e-180 638.6 Lactobacillaceae ftsY ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 Bacteria 1TPRI@1239,3F3YC@33958,4HA6A@91061,COG0552@1,COG0552@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) FFAGCILK_02618 543734.LCABL_18200 0.0 1913.3 Lactobacillaceae smc ko:K03529 ko00000,ko03036 Bacteria 1TPJV@1239,3F478@33958,4HB89@91061,COG1196@1,COG1196@2 NA|NA|NA D Required for chromosome condensation and partitioning FFAGCILK_02619 543734.LCABL_18210 1.7e-125 455.3 Lactobacillaceae rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Bacteria 1TPGC@1239,3F564@33958,4HAWU@91061,COG0571@1,COG0571@2 NA|NA|NA J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism FFAGCILK_02620 543734.LCABL_18220 0.0 1097.4 Lactobacillaceae oppA1 ko:K02035 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 1TQ0N@1239,3F3KW@33958,4HARF@91061,COG0747@1,COG0747@2 NA|NA|NA E ABC transporter substrate-binding protein FFAGCILK_02621 543734.LCABL_18230 1.4e-135 489.2 Lactobacillaceae oppC ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TP4R@1239,3FCB6@33958,4HA7I@91061,COG1173@1,COG1173@2 NA|NA|NA EP Binding-protein-dependent transport system inner membrane component FFAGCILK_02622 1423816.BACQ01000007_gene212 9.2e-170 602.8 Lactobacillaceae oppB ko:K02033,ko:K02034,ko:K13894 ko02010,ko02024,map02010,map02024 M00239,M00349 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 Bacteria 1TP1S@1239,3FCCU@33958,4HATR@91061,COG0601@1,COG0601@2 NA|NA|NA P ABC transporter permease FFAGCILK_02623 543734.LCABL_18260 4.1e-178 630.6 Lactobacillaceae oppF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02032,ko:K10823,ko:K12372,ko:K13892 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00324,M00348,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.11,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1V36J@1239,3F4GM@33958,4H9YB@91061,COG4608@1,COG4608@2 NA|NA|NA P Belongs to the ABC transporter superfamily FFAGCILK_02624 543734.LCABL_18270 5.7e-194 683.3 Lactobacillaceae oppD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1TP6E@1239,3F41T@33958,4HA4E@91061,COG0444@1,COG0444@2 NA|NA|NA P Belongs to the ABC transporter superfamily FFAGCILK_02625 543734.LCABL_18280 3e-37 160.6 Lactobacillaceae acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 ko:K02078 ko00000,ko00001 Bacteria 1VEE3@1239,3F7F4@33958,4HNQ0@91061,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis FFAGCILK_02626 543734.LCABL_18290 9.8e-186 656.0 Lactobacillaceae plsX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPXS@1239,3F4N9@33958,4HA0R@91061,COG0416@1,COG0416@2 NA|NA|NA I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA FFAGCILK_02627 543734.LCABL_18300 0.0 1327.0 Lactobacillaceae recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TQ6I@1239,3F3JW@33958,4HAWN@91061,COG1200@1,COG1200@2 NA|NA|NA L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) FFAGCILK_02628 543734.LCABL_18310 1e-309 1068.5 Lactobacillaceae yloV ko:K07030 ko00000 Bacteria 1TQMX@1239,3F3X0@33958,4HBSE@91061,COG1461@1,COG1461@2 NA|NA|NA S DAK2 domain fusion protein YloV FFAGCILK_02629 543734.LCABL_18320 2.3e-57 228.0 Lactobacillaceae asp Bacteria 1V731@1239,3F72W@33958,4HIS4@91061,COG1302@1,COG1302@2 NA|NA|NA S Asp23 family, cell envelope-related function FFAGCILK_02630 543734.LCABL_18330 2.4e-26 124.0 Lactobacillaceae rpmB GO:0003674,GO:0003735,GO:0005198 ko:K02902 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEI2@1239,3F7ZN@33958,4HNIK@91061,COG0227@1,COG0227@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL28 family FFAGCILK_02631 543734.LCABL_18340 3.5e-128 464.2 Lactobacillaceae thiN 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 R00619 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1VA0W@1239,3F4N8@33958,4HHS1@91061,COG1564@1,COG1564@2 NA|NA|NA H thiamine pyrophosphokinase FFAGCILK_02632 543734.LCABL_18350 3.6e-117 427.6 Lactobacillaceae rpe 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQK8@1239,3F4KX@33958,4H9RW@91061,COG0036@1,COG0036@2 NA|NA|NA G Belongs to the ribulose-phosphate 3-epimerase family FFAGCILK_02633 543734.LCABL_18360 3.8e-173 614.0 Lactobacillaceae rsgA 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 Bacteria 1TPSQ@1239,3F3XH@33958,4HA9W@91061,COG1162@1,COG1162@2 NA|NA|NA S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit FFAGCILK_02634 543734.LCABL_18370 0.0 1136.3 Lactobacillaceae prkC GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 ko:K12132 ko00000,ko01000,ko01001 Bacteria 1TP3F@1239,3F4G6@33958,4H9KD@91061,COG0515@1,COG0515@2,COG2815@1,COG2815@2 NA|NA|NA KLT serine threonine protein kinase FFAGCILK_02635 543734.LCABL_18380 9.7e-135 486.1 Lactobacillaceae stp 3.1.3.16 ko:K20074 ko00000,ko01000,ko01009 Bacteria 1V6K5@1239,3F4UI@33958,4HCDR@91061,COG0631@1,COG0631@2 NA|NA|NA T phosphatase FFAGCILK_02636 543734.LCABL_18390 8.4e-254 882.5 Lactobacillaceae sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 ko00000,ko01000,ko03009 Bacteria 1TP3N@1239,3F45F@33958,4HBQ6@91061,COG0144@1,COG0144@2,COG0781@1,COG0781@2 NA|NA|NA J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA FFAGCILK_02637 543734.LCABL_18400 5e-176 623.6 Lactobacillaceae fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 R03940 RC00026,RC00165 ko00000,ko00001,ko01000 iSB619.SA_RS06010 Bacteria 1TQ32@1239,3F4N7@33958,4HART@91061,COG0223@1,COG0223@2 NA|NA|NA J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus FFAGCILK_02638 543734.LCABL_18410 0.0 1597.8 Lactobacillaceae priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TNYB@1239,3F3N8@33958,4H9WW@91061,COG1198@1,COG1198@2 NA|NA|NA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA FFAGCILK_02639 543734.LCABL_18420 4.7e-216 756.9 Lactobacillaceae coaBC 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPP3@1239,3F3XX@33958,4HAK8@91061,COG0452@1,COG0452@2 NA|NA|NA H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine FFAGCILK_02640 543734.LCABL_18430 1.3e-35 155.2 Lactobacillaceae rpoZ GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1VK74@1239,3F81N@33958,4HNHS@91061,COG1758@1,COG1758@2 NA|NA|NA K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits FFAGCILK_02641 543734.LCABL_18440 1.9e-115 421.8 Lactobacillaceae gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15680 Bacteria 1TP0M@1239,3F3X9@33958,4HAYW@91061,COG0194@1,COG0194@2 NA|NA|NA F Essential for recycling GMP and indirectly, cGMP FFAGCILK_02642 1423816.BACQ01000007_gene192 1.6e-91 342.4 Lactobacillaceae rssA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0044424,GO:0044444,GO:0044464 ko:K07001 ko00000 Bacteria 1UXU0@1239,3F92T@33958,4IBIE@91061,COG1752@1,COG1752@2 NA|NA|NA S Patatin-like phospholipase FFAGCILK_02643 543734.LCABL_18470 1.9e-49 201.4 Lactobacillaceae Bacteria 1U6H7@1239,2DKQQ@1,30ACZ@2,3F7X5@33958,4IG9I@91061 NA|NA|NA FFAGCILK_02644 543734.LCABL_18490 0.0 1075.8 Lactobacillaceae recN GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360 ko:K03631,ko:K13582 ko04112,map04112 ko00000,ko00001,ko03400 Bacteria 1TP99@1239,3F43U@33958,4H9ZR@91061,COG0497@1,COG0497@2 NA|NA|NA L May be involved in recombinational repair of damaged DNA FFAGCILK_02645 543734.LCABL_18500 4.4e-74 283.9 Lactobacillaceae argR GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 ko:K03402 ko00000,ko03000 Bacteria 1V1R7@1239,3F71C@33958,4HFY8@91061,COG1438@1,COG1438@2 NA|NA|NA K Regulates arginine biosynthesis genes FFAGCILK_02646 543734.LCABL_18510 3.6e-154 550.8 Lactobacillaceae rrmJ 2.1.1.226,2.1.1.227 ko:K06442 ko00000,ko01000,ko03009 Bacteria 1TPE4@1239,3F45T@33958,4HAPY@91061,COG1189@1,COG1189@2 NA|NA|NA J Ribosomal RNA large subunit methyltransferase J FFAGCILK_02647 543734.LCABL_18520 1e-148 532.7 Lactobacillaceae ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 ko:K00795,ko:K02523,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061,R09248 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1TPQY@1239,3F436@33958,4HA8E@91061,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family FFAGCILK_02648 543734.LCABL_18530 1.6e-32 144.8 Lactobacillaceae xseB 3.1.11.6 ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1VK9I@1239,3F81K@33958,4HNRB@91061,COG1722@1,COG1722@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides FFAGCILK_02649 1423732.BALS01000003_gene867 4.1e-200 704.1 Lactobacillaceae xseA 3.1.11.6 ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TP4E@1239,3F4RE@33958,4HAN2@91061,COG1570@1,COG1570@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides FFAGCILK_02650 543734.LCABL_18550 1.6e-149 535.4 Lactobacillaceae folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP1P@1239,3F46A@33958,4H9Q6@91061,COG0190@1,COG0190@2 NA|NA|NA F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate FFAGCILK_02651 543734.LCABL_18560 1.1e-66 259.2 Lactobacillaceae nusB ko:K03625 ko00000,ko03009,ko03021 Bacteria 1VA9B@1239,3F7KW@33958,4HKMU@91061,COG0781@1,COG0781@2 NA|NA|NA K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons FFAGCILK_02652 543734.LCABL_18570 2.2e-76 291.6 Lactobacillaceae yqhY ko:K10947 ko00000,ko03000 Bacteria 1V4IC@1239,3F71X@33958,4HJ7T@91061,COG1302@1,COG1302@2 NA|NA|NA S Asp23 family, cell envelope-related function FFAGCILK_02653 543734.LCABL_18580 1.1e-101 375.9 Lactobacillaceae efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02356 ko00000,ko03012 Bacteria 1TR8P@1239,3F422@33958,4H9YX@91061,COG0231@1,COG0231@2 NA|NA|NA J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase FFAGCILK_02655 543734.LCABL_18590 7.7e-202 709.5 Lactobacillaceae pepP 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 ko00000,ko01000,ko01002 Bacteria 1TQ44@1239,3F4DR@33958,4HAT7@91061,COG0006@1,COG0006@2 NA|NA|NA E Creatinase/Prolidase N-terminal domain FFAGCILK_02656 543734.LCABL_18600 1.7e-47 194.9 Lactobacillaceae rpmA GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 ko:K02899 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6HW@1239,3F6WU@33958,4HIMN@91061,COG0211@1,COG0211@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL27 family FFAGCILK_02657 543734.LCABL_18610 1.1e-56 225.7 Lactobacillaceae ysxB ko:K07584 ko00000 Bacteria 1VEQ9@1239,3F839@33958,4HNMV@91061,COG2868@1,COG2868@2 NA|NA|NA J Cysteine protease Prp FFAGCILK_02658 543734.LCABL_18620 4.5e-49 200.3 Lactobacillaceae rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02888 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V9YH@1239,3F6WT@33958,4HIGK@91061,COG0261@1,COG0261@2 NA|NA|NA J This protein binds to 23S rRNA in the presence of protein L20 FFAGCILK_02659 1423816.BACQ01000007_gene175 3.2e-11 73.2 Lactobacillaceae Bacteria 1U87T@1239,29QJP@1,30BJ9@2,3FANH@33958,4II5H@91061 NA|NA|NA FFAGCILK_02660 1423734.JCM14202_3414 5.3e-30 137.1 Lactobacillaceae Bacteria 1W6RP@1239,292E4@1,2ZPYC@2,3F8JE@33958,4I1K9@91061 NA|NA|NA FFAGCILK_02662 543734.LCABL_18670 0.0 1593.2 Lactobacillaceae pepX 3.4.14.11 ko:K01281 ko00000,ko01000,ko01002 Bacteria 1TT78@1239,3F44E@33958,4HBA0@91061,COG2936@1,COG2936@2 NA|NA|NA E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline FFAGCILK_02663 543734.LCABL_18680 5.4e-261 906.4 Lactobacillaceae glnA 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 1TNZA@1239,3F41A@33958,4HACE@91061,COG0174@1,COG0174@2 NA|NA|NA E glutamine synthetase FFAGCILK_02664 543734.LCABL_18690 1e-60 239.2 Lactobacillaceae glnR GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2001141 ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 ko00000,ko00001,ko00002,ko02000,ko03000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 Bacteria 1V6JE@1239,3F7RX@33958,4HKM6@91061,COG0789@1,COG0789@2 NA|NA|NA K Transcriptional regulator FFAGCILK_02665 543734.LCABL_18700 0.0 1369.8 Lactobacillaceae yaaO 4.1.1.17,4.1.1.19 ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 M00133,M00134 R00566,R00670 RC00299 ko00000,ko00001,ko00002,ko01000 Bacteria 1TNZ9@1239,3F3TV@33958,4HBGC@91061,COG1982@1,COG1982@2 NA|NA|NA E Orn/Lys/Arg decarboxylase, C-terminal domain FFAGCILK_02666 543734.LCABL_18710 1.6e-238 831.6 Lactobacillaceae ynbB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 4.4.1.1 ko:K01758 ko00260,ko00270,ko00450,ko01100,ko01130,ko01230,map00260,map00270,map00450,map01100,map01130,map01230 M00338 R00782,R01001,R02408,R04770,R04930,R09366 RC00056,RC00069,RC00348,RC00382,RC00710,RC01209,RC01210,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TQ88@1239,3F3PU@33958,4HAF5@91061,COG4100@1,COG4100@2 NA|NA|NA P aluminum resistance FFAGCILK_02667 543734.LCABL_18720 3.9e-173 614.0 Lactobacillaceae miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 Bacteria 1TPSC@1239,3F3XS@33958,4HAVW@91061,COG0324@1,COG0324@2 NA|NA|NA F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) FFAGCILK_02668 543734.LCABL_18730 1.5e-25 121.3 Lactobacillaceae WQ51_02665 Bacteria 1VPEZ@1239,2C91M@1,33E1E@2,3F8C0@33958,4HRR2@91061 NA|NA|NA S Protein of unknown function (DUF3042) FFAGCILK_02669 543734.LCABL_18740 2.6e-73 281.2 Lactobacillaceae yqhL Bacteria 1VAI7@1239,3F67E@33958,4HKCE@91061,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese-like protein FFAGCILK_02670 543734.LCABL_18750 1.8e-178 631.7 Lactobacillaceae glk GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS07790 Bacteria 1TPKW@1239,3F4F0@33958,4HBAU@91061,COG1940@1,COG1940@2 NA|NA|NA G Glucokinase FFAGCILK_02671 543734.LCABL_18760 6.2e-41 172.9 Lactobacillaceae yqgQ Bacteria 1VK83@1239,3F83I@33958,4HRG2@91061,COG4483@1,COG4483@2 NA|NA|NA S Bacterial protein of unknown function (DUF910) FFAGCILK_02672 543734.LCABL_18770 7.3e-121 439.9 Lactobacillaceae gluP 3.4.21.105 ko:K19225 ko00000,ko01000,ko01002 Bacteria 1TQXT@1239,3F3WR@33958,4HCDF@91061,COG0705@1,COG0705@2 NA|NA|NA S Peptidase, S54 family FFAGCILK_02673 543734.LCABL_18780 0.0 1366.3 Lactobacillaceae pbp2b 3.4.16.4 ko:K00687,ko:K05515,ko:K12553,ko:K21465 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Bacteria 1TQHY@1239,3F3KH@33958,4HAFX@91061,COG0768@1,COG0768@2 NA|NA|NA M Penicillin-binding Protein FFAGCILK_02674 543734.LCABL_18810 0.0 1596.6 Lactobacillaceae Bacteria 1TRR1@1239,3FC7P@33958,4HCR9@91061,COG4485@1,COG4485@2 NA|NA|NA S Bacterial membrane protein YfhO FFAGCILK_02675 543734.LCABL_18820 2.1e-54 218.0 Lactobacillaceae yneR Bacteria 1VEQE@1239,3F7SB@33958,4HNU2@91061,COG4841@1,COG4841@2 NA|NA|NA S Belongs to the HesB IscA family FFAGCILK_02676 543734.LCABL_18830 6.9e-116 423.3 Lactobacillaceae vraR ko:K07694,ko:K11618 ko02020,map02020 M00480,M00481,M00754 ko00000,ko00001,ko00002,ko02022 Bacteria 1TQ1U@1239,3F4DN@33958,4HA4B@91061,COG2197@1,COG2197@2 NA|NA|NA K helix_turn_helix, Lux Regulon FFAGCILK_02677 543734.LCABL_18840 9.2e-179 632.9 Lactobacillaceae vraS 2.7.13.3 ko:K07673,ko:K07681,ko:K11617 ko02020,map02020 M00471,M00480,M00481,M00754 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TPDG@1239,3FC2U@33958,4HC7E@91061,COG4585@1,COG4585@2 NA|NA|NA T Histidine kinase FFAGCILK_02678 543734.LCABL_18850 3.2e-119 434.5 Lactobacillaceae yvqF ko:K11622 ko02020,map02020 ko00000,ko00001 Bacteria 1V3D0@1239,3F5S1@33958,4HDIA@91061,COG4758@1,COG4758@2 NA|NA|NA S Cell wall-active antibiotics response 4TMS YvqF FFAGCILK_02679 543734.LCABL_18860 6.9e-78 296.6 Lactobacillaceae greA GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 ko:K03624 ko00000,ko03021 Bacteria 1V44S@1239,3F4ZF@33958,4HGZU@91061,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides FFAGCILK_02680 543734.LCABL_18870 4.7e-114 417.2 Lactobacillaceae udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 iSBO_1134.SBO_0893 Bacteria 1TQ4V@1239,3F3KE@33958,4HAVR@91061,COG0572@1,COG0572@2 NA|NA|NA F Cytidine monophosphokinase FFAGCILK_02681 543734.LCABL_18880 1.5e-206 725.3 Lactobacillaceae mltG ko:K07082 ko00000 Bacteria 1TS48@1239,3F4IG@33958,4HAUV@91061,COG1559@1,COG1559@2 NA|NA|NA S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation FFAGCILK_02682 543734.LCABL_18900 0.0 1581.2 Lactobacillaceae pheT GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_2160,iPC815.YPO2428 Bacteria 1TP98@1239,3F3V3@33958,4HAQ9@91061,COG0072@1,COG0072@2 NA|NA|NA J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily FFAGCILK_02683 543734.LCABL_18910 1.3e-201 708.8 Lactobacillaceae pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPFW@1239,3F4NT@33958,4HAVN@91061,COG0016@1,COG0016@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily FFAGCILK_02684 543734.LCABL_18920 6.3e-66 256.5 Lactobacillaceae yodB Bacteria 1VBI7@1239,3F7FK@33958,4HKBR@91061,COG1733@1,COG1733@2 NA|NA|NA K Transcriptional regulator, HxlR family FFAGCILK_02685 1423732.BALS01000034_gene290 7.3e-94 349.7 Lactobacillaceae XK27_09705 6.1.1.14 ko:K01879,ko:K06950 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1V4QX@1239,3F64N@33958,4HHW0@91061,COG1418@1,COG1418@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. FFAGCILK_02686 543734.LCABL_18940 5.1e-139 500.4 Lactobacillaceae spoU 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 1V3JP@1239,3F3NF@33958,4HCF5@91061,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family FFAGCILK_02687 543734.LCABL_18950 1.9e-45 188.3 Lactobacillaceae acyP GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 iSB619.SA_RS07020,iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036 Bacteria 1VEM9@1239,3F81R@33958,4HNN7@91061,COG1254@1,COG1254@2 NA|NA|NA C Belongs to the acylphosphatase family FFAGCILK_02688 543734.LCABL_18960 6.4e-174 616.7 Lactobacillaceae yidC ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 1TSDN@1239,3F3P3@33958,4HCC8@91061,COG0706@1,COG0706@2 NA|NA|NA U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins FFAGCILK_02689 543734.LCABL_18970 2.9e-290 1003.8 Lactobacillaceae arlS GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K18940 ko02020,map02020 M00716,M00717 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TPSK@1239,3F3NU@33958,4HAH5@91061,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase FFAGCILK_02690 543734.LCABL_18980 7.9e-123 446.4 Lactobacillaceae Bacteria 1TS81@1239,3F421@33958,4H9NE@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator FFAGCILK_02691 543734.LCABL_18990 9.1e-267 925.6 Lactobacillaceae gnd GO:0003674,GO:0003824,GO:0004616,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019520,GO:0019521,GO:0019637,GO:0019682,GO:0019693,GO:0019752,GO:0032787,GO:0034641,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046176,GO:0046177,GO:0046395,GO:0046483,GO:0046496,GO:0046983,GO:0051156,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072329,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 iECS88_1305.ECS88_2128,iECW_1372.ECW_m2189,iEKO11_1354.EKO11_1765,iPC815.YPO1541,iWFL_1372.ECW_m2189 Bacteria 1TP4I@1239,3F3S8@33958,4H9NC@91061,COG0362@1,COG0362@2 NA|NA|NA H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH FFAGCILK_02692 543734.LCABL_19010 1.6e-97 362.1 Lactobacillaceae yceD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 ko:K07040 ko00000 Bacteria 1VB08@1239,3F61Z@33958,4HME9@91061,COG1399@1,COG1399@2 NA|NA|NA S Uncharacterized ACR, COG1399 FFAGCILK_02693 543734.LCABL_19020 4.8e-210 736.9 Lactobacillaceae ylbM Bacteria 1TPP2@1239,3F3QC@33958,4HAZJ@91061,COG1323@1,COG1323@2 NA|NA|NA S Belongs to the UPF0348 family FFAGCILK_02694 543734.LCABL_19030 2.7e-137 494.6 Lactobacillaceae yccK Bacteria 1UIVS@1239,3FBXC@33958,4ISTS@91061,COG0500@1,COG0500@2 NA|NA|NA Q ubiE/COQ5 methyltransferase family FFAGCILK_02695 543734.LCABL_19040 1.9e-59 235.0 Lactobacillaceae rsfS GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 ko:K09710 ko00000,ko03009 Bacteria 1VA2Z@1239,3F7QN@33958,4HKEJ@91061,COG0799@1,COG0799@2 NA|NA|NA J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation FFAGCILK_02696 543734.LCABL_19050 5.6e-109 400.2 Lactobacillaceae nadD 2.7.6.3,2.7.7.18 ko:K00950,ko:K00969,ko:K06950 ko00760,ko00790,ko01100,map00760,map00790,map01100 M00115,M00126,M00841 R00137,R03005,R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V6Y1@1239,3F47C@33958,4HHRY@91061,COG1713@1,COG1713@2 NA|NA|NA H Hydrolase, HD family FFAGCILK_02697 543734.LCABL_19060 5.7e-123 446.8 Lactobacillaceae nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 ko:K00969,ko:K03574 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1V3SK@1239,3F4D6@33958,4HGXK@91061,COG1057@1,COG1057@2 NA|NA|NA H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) FFAGCILK_02698 543734.LCABL_19070 3.8e-48 197.2 Lactobacillaceae yhbY GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275 ko:K07574 ko00000,ko03009 Bacteria 1VEGM@1239,3F7EW@33958,4HKC7@91061,COG1534@1,COG1534@2 NA|NA|NA J RNA-binding protein FFAGCILK_02699 543734.LCABL_19080 1.4e-206 725.3 Lactobacillaceae yqeH GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113 ko:K06948 ko00000,ko03009 Bacteria 1TPM2@1239,3F4JU@33958,4HAAF@91061,COG1161@1,COG1161@2 NA|NA|NA S Ribosome biogenesis GTPase YqeH FFAGCILK_02700 543734.LCABL_19090 2.9e-96 357.8 Lactobacillaceae yqeG ko:K07015 ko00000 Bacteria 1V6KM@1239,3F46V@33958,4HGAV@91061,COG2179@1,COG2179@2 NA|NA|NA S HAD phosphatase, family IIIA FFAGCILK_02701 543734.LCABL_19100 9.2e-172 609.4 Lactobacillaceae ykcA Bacteria 1VWUR@1239,3FB66@33958,4HXTS@91061,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FFAGCILK_02702 543734.LCABL_19110 1.6e-190 671.8 Lactobacillaceae mhqA 3.4.21.26 ko:K01322,ko:K15975 ko04614,map04614 ko00000,ko00001,ko01000,ko01002 Bacteria 1TP7I@1239,3F4PB@33958,4H9ND@91061,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FFAGCILK_02703 543734.LCABL_19120 4.8e-122 443.7 Lactobacillaceae mhqD ko:K06999 ko00000 Bacteria 1TPBY@1239,3F6EM@33958,4HB45@91061,COG0400@1,COG0400@2 NA|NA|NA S Dienelactone hydrolase family FFAGCILK_02704 543734.LCABL_19130 1.3e-179 635.6 Lactobacillaceae 3.5.1.10 ko:K01433 ko00630,ko00670,map00630,map00670 R00944 RC00026,RC00111 ko00000,ko00001,ko01000 Bacteria 1V7QI@1239,3F69N@33958,4HJMD@91061,COG0604@1,COG0604@2 NA|NA|NA C Alcohol dehydrogenase GroES-like domain FFAGCILK_02705 543734.LCABL_19140 7.2e-98 363.2 Lactobacillaceae yvdD 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 1UKED@1239,3F5U4@33958,4HE2X@91061,COG1611@1,COG1611@2 NA|NA|NA S Belongs to the LOG family FFAGCILK_02706 543734.LCABL_19150 8.7e-57 226.1 Lactobacillaceae rplT GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02887 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6DB@1239,3F6HZ@33958,4HH2W@91061,COG0292@1,COG0292@2 NA|NA|NA J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit FFAGCILK_02707 543734.LCABL_19160 9e-27 125.6 Lactobacillaceae rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02916 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VF5W@1239,3F7CQ@33958,4HNIQ@91061,COG0291@1,COG0291@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL35 family FFAGCILK_02708 543734.LCABL_19170 1.5e-77 295.4 Lactobacillaceae infC GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 ko:K02520 ko00000,ko03012,ko03029 Bacteria 1V1RC@1239,3F4MS@33958,4HFUS@91061,COG0290@1,COG0290@2 NA|NA|NA J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins FFAGCILK_02709 543734.LCABL_19180 2.6e-129 468.0 Bacilli Bacteria 1VJJ0@1239,2DMFR@1,32R83@2,4HQP8@91061 NA|NA|NA S SseB protein N-terminal domain FFAGCILK_02710 568703.LGG_01753 1.6e-53 215.7 Lactobacillaceae Bacteria 1U7IT@1239,29Q5P@1,30B4K@2,3F9S3@33958,4IHFJ@91061 NA|NA|NA FFAGCILK_02711 543734.LCABL_19200 9.2e-101 372.9 Lactobacillaceae yrgI 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1V8SE@1239,3F86H@33958,4HJCU@91061,COG0406@1,COG0406@2 NA|NA|NA G Histidine phosphatase superfamily (branch 1) FFAGCILK_02712 543734.LCABL_19210 0.0 1332.4 Lactobacillaceae thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP78@1239,3F3TC@33958,4HABZ@91061,COG0441@1,COG0441@2 NA|NA|NA J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) FFAGCILK_02714 568703.LGG_01756 1e-141 509.6 Lactobacillaceae dnaI GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 ko:K11144 ko00000,ko03032 Bacteria 1TPZX@1239,3F4JK@33958,4HABS@91061,COG1484@1,COG1484@2 NA|NA|NA L Primosomal protein DnaI FFAGCILK_02715 543734.LCABL_19240 4.1e-240 837.0 Lactobacillaceae dnaB ko:K03346 ko00000,ko03032 Bacteria 1TSBB@1239,3F5D7@33958,4H9RI@91061,COG3611@1,COG3611@2 NA|NA|NA L replication initiation and membrane attachment FFAGCILK_02716 543734.LCABL_19250 1.2e-79 302.4 Lactobacillaceae nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K07738 ko00000,ko03000 Bacteria 1V3JA@1239,3F65S@33958,4HGXA@91061,COG1327@1,COG1327@2 NA|NA|NA K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes FFAGCILK_02717 543734.LCABL_19260 1.2e-98 365.9 Lactobacillaceae coaE 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1V6FS@1239,3F6WF@33958,4HII3@91061,COG0237@1,COG0237@2 NA|NA|NA F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A FFAGCILK_02718 543734.LCABL_19270 1.2e-157 562.4 Lactobacillaceae fpg 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPM9@1239,3F43E@33958,4H9Q7@91061,COG0266@1,COG0266@2 NA|NA|NA L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates FFAGCILK_02719 543734.LCABL_19280 0.0 1724.5 Lactobacillaceae polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 1TPKJ@1239,3F3ZA@33958,4H9S7@91061,COG0258@1,COG0258@2,COG0749@1,COG0749@2 NA|NA|NA L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity FFAGCILK_02720 543734.LCABL_19290 1.7e-120 438.7 Lactobacillaceae ybhL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06890 ko00000 Bacteria 1V9CJ@1239,3FBMQ@33958,4HM3D@91061,COG0670@1,COG0670@2 NA|NA|NA S Inhibitor of apoptosis-promoting Bax1 FFAGCILK_02721 543734.LCABL_19300 9.1e-253 879.0 Lactobacillaceae mpl GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0042802,GO:0044424,GO:0044464 6.3.2.4,6.3.2.45,6.3.2.8 ko:K01921,ko:K01924,ko:K02558 ko00471,ko00473,ko00550,ko01100,ko01502,map00471,map00473,map00550,map01100,map01502 R01150,R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 iSDY_1059.SDY_4251 Bacteria 1TQ5H@1239,3F49J@33958,4HAR4@91061,COG0773@1,COG0773@2 NA|NA|NA M Belongs to the MurCDEF family FFAGCILK_02722 543734.LCABL_19310 0.0 1413.7 Lactobacillaceae sftA ko:K03466 ko00000,ko03036 3.A.12 Bacteria 1TPJR@1239,3F441@33958,4HA1S@91061,COG1674@1,COG1674@2 NA|NA|NA D Belongs to the FtsK SpoIIIE SftA family FFAGCILK_02723 543734.LCABL_19320 1.1e-115 422.5 Lactobacillaceae pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890,ko:K06878 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1V7QA@1239,3FBJ0@33958,4HJBD@91061,COG0073@1,COG0073@2 NA|NA|NA J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily FFAGCILK_02724 543734.LCABL_19330 1.5e-55 221.9 Lactobacillaceae ytpP GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 2.7.1.180,5.3.4.1 ko:K01829,ko:K03671,ko:K03734,ko:K06196 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko02000,ko03110 5.A.1.2 Bacteria 1VAS6@1239,3F72K@33958,4HKGM@91061,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin FFAGCILK_02726 543734.LCABL_19350 2e-120 438.3 Lactobacillaceae trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.297,2.1.1.33 ko:K02493,ko:K03439 R10806 RC00003,RC03279 ko00000,ko01000,ko03012,ko03016 Bacteria 1TQCA@1239,3F3QM@33958,4HC08@91061,COG0220@1,COG0220@2 NA|NA|NA J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA FFAGCILK_02727 543734.LCABL_19370 1e-147 529.3 Lactobacillaceae ytmP 2.7.1.89 ko:K07251 ko00730,ko01100,map00730,map01100 R02134 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1UMFY@1239,3F4GU@33958,4HBF9@91061,COG0510@1,COG0510@2 NA|NA|NA M Choline/ethanolamine kinase FFAGCILK_02728 543734.LCABL_19380 1.3e-216 758.8 Lactobacillaceae ecsB ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V1VG@1239,3F4HH@33958,4HG1K@91061,COG4473@1,COG4473@2 NA|NA|NA U ABC transporter FFAGCILK_02729 543734.LCABL_19390 3.1e-133 481.1 Lactobacillaceae ecsA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQIH@1239,3F444@33958,4HA2B@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter, ATP-binding protein FFAGCILK_02730 543734.LCABL_19400 1.6e-76 292.0 Lactobacillaceae hit ko:K02503 ko00000,ko04147 Bacteria 1V9ZJ@1239,3F6K5@33958,4HIG2@91061,COG0537@1,COG0537@2 NA|NA|NA FG histidine triad FFAGCILK_02731 543734.LCABL_19410 2.7e-61 241.1 Lactobacillaceae yhaH Bacteria 1VM8M@1239,3F7TT@33958,4HR25@91061,COG4980@1,COG4980@2 NA|NA|NA S YtxH-like protein FFAGCILK_02732 543734.LCABL_19420 8.1e-160 569.7 Lactobacillaceae prsA 5.2.1.8 ko:K02597,ko:K07533 ko00000,ko01000,ko03110 Bacteria 1TX3R@1239,3F45W@33958,4HC85@91061,COG0760@1,COG0760@2 NA|NA|NA M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins FFAGCILK_02733 543734.LCABL_19430 1.4e-181 642.1 Lactobacillaceae yhaM GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 ko:K03698 ko00000,ko01000,ko03019 Bacteria 1TPIU@1239,3F4SF@33958,4HB1M@91061,COG3481@1,COG3481@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. FFAGCILK_02734 543734.LCABL_19440 1e-54 219.2 Lactobacillaceae yheA Bacteria 1V62T@1239,3FBP8@33958,4IRH3@91061,COG3679@1,COG3679@2 NA|NA|NA S Control of competence regulator ComK, YlbF/YmcA FFAGCILK_02735 543734.LCABL_19450 0.0 1348.6 Lactobacillaceae pbp2A 2.4.1.129,3.4.16.4 ko:K03693,ko:K05365,ko:K05366,ko:K12555,ko:K21464 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 1TPM5@1239,3F49Q@33958,4H9SA@91061,COG0744@1,COG0744@2 NA|NA|NA M penicillin-binding protein FFAGCILK_02736 543734.LCABL_19460 6.1e-154 550.1 Lactobacillaceae rluA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 ko00000,ko01000,ko03009 Bacteria 1TSM6@1239,3F50K@33958,4HA7M@91061,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil FFAGCILK_02737 543734.LCABL_19470 5.3e-75 287.0 Lactobacillaceae argR GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 ko:K03402 ko00000,ko03000 Bacteria 1V1R7@1239,3FBR5@33958,4HN5H@91061,COG1438@1,COG1438@2 NA|NA|NA K Regulates arginine biosynthesis genes FFAGCILK_02738 543734.LCABL_19480 0.0 1115.1 Lactobacillaceae argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TPEZ@1239,3F4DE@33958,4HAR3@91061,COG0018@1,COG0018@2 NA|NA|NA J Arginyl-tRNA synthetase FFAGCILK_02740 543734.LCABL_19500 1.2e-67 262.3 Lactobacillaceae Bacteria 1U6R7@1239,2A8KV@1,30XP9@2,3F8CJ@33958,4IGII@91061 NA|NA|NA FFAGCILK_02741 543734.LCABL_19510 2.1e-22 110.9 Lactobacillaceae Bacteria 1U8CT@1239,29QNK@1,30BN8@2,3FAUE@33958,4IIAS@91061 NA|NA|NA FFAGCILK_02742 543734.LCABL_19520 5.2e-178 630.2 Lactobacillaceae pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 ko:K00226,ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPFV@1239,3FC4P@33958,4HBFE@91061,COG0167@1,COG0167@2 NA|NA|NA F Catalyzes the conversion of dihydroorotate to orotate FFAGCILK_02743 543734.LCABL_19530 0.0 1159.4 Lactobacillaceae glpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1UG1C@1239,3F3SZ@33958,4HCPQ@91061,COG0584@1,COG0584@2,COG4781@1,COG4781@2 NA|NA|NA C phosphodiesterase FFAGCILK_02744 543734.LCABL_19540 5.1e-122 443.7 Lactobacillaceae mecA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K16511 ko00000 Bacteria 1UZ7D@1239,3F5G4@33958,4HID6@91061,COG4862@1,COG4862@2 NA|NA|NA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis FFAGCILK_02745 543734.LCABL_19550 3.2e-68 264.2 Lactobacillaceae spxA 1.20.4.1 ko:K00537,ko:K16509 ko00000,ko01000 Bacteria 1V3QC@1239,3F6HJ@33958,4HH0I@91061,COG1393@1,COG1393@2 NA|NA|NA K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress FFAGCILK_02746 543734.LCABL_19560 3.1e-136 491.1 Lactobacillaceae yhfI GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 Bacteria 1V1TF@1239,3F4U0@33958,4HFNV@91061,COG1234@1,COG1234@2 NA|NA|NA S Metallo-beta-lactamase superfamily FFAGCILK_02747 568703.LGG_02885 2.8e-75 289.3 Lactobacillaceae sip Bacteria 1TTJI@1239,3F4IB@33958,4HDG6@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family FFAGCILK_02749 1220589.CD32_18175 4.8e-07 60.5 Lysinibacillus Bacteria 1VP8A@1239,2DSAH@1,33F8N@2,3IYYK@400634,4HR5Z@91061 NA|NA|NA FFAGCILK_02750 568703.LGG_01518 2.8e-69 267.7 Bacilli Bacteria 1VD12@1239,2DGU4@1,32U7Y@2,4HXN9@91061 NA|NA|NA FFAGCILK_02751 568703.LGG_01519 5.6e-190 670.2 Lactobacillaceae GO:0008150,GO:0009405,GO:0044419,GO:0051704 ko:K02656,ko:K07273,ko:K14196 ko05150,map05150 ko00000,ko00001,ko02035,ko02044 Bacteria 1V16P@1239,3FC13@33958,4HF99@91061,COG1388@1,COG1388@2,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 FFAGCILK_02752 1423732.BALS01000002_gene1061 6.4e-46 189.9 Lactobacillaceae Bacteria 1W0SS@1239,2FDCN@1,345EF@2,3F8B6@33958,4HXYE@91061 NA|NA|NA S Bacteriophage holin of superfamily 6 (Holin_LLH) FFAGCILK_02753 568703.LGG_01521 1.9e-30 137.9 Lactobacillaceae Bacteria 1W39V@1239,2C0XI@1,2ZJRZ@2,3F76K@33958,4I12U@91061 NA|NA|NA FFAGCILK_02755 568703.LGG_01140 1.8e-09 68.6 Lactobacillaceae Bacteria 1U7KU@1239,2BJKG@1,32DXP@2,3F9VT@33958,4IHHX@91061 NA|NA|NA FFAGCILK_02756 146269.A8YQK1_9CAUD 0.0 1143.3 Siphoviridae Viruses 4QAK6@10239,4QKKV@10699,4QPBY@28883,4QUP9@35237 NA|NA|NA S peptidoglycan catabolic process FFAGCILK_02757 146269.Q7Y4B1_9CAUD 1.1e-163 583.6 Siphoviridae GO:0005575,GO:0019012,GO:0044423,GO:0098015 Viruses 4QBF8@10239,4QKN2@10699,4QPI9@28883,4QUS7@35237 NA|NA|NA S Phage tail protein FFAGCILK_02758 1423732.BALS01000126_gene2495 6.5e-276 957.6 Lactobacillaceae xkdO Bacteria 1UYS4@1239,3FBSQ@33958,4HEDZ@91061,COG3953@1,COG3953@2,COG5412@1,COG5412@2 NA|NA|NA D NLP P60 protein FFAGCILK_02759 1423732.BALS01000063_gene2229 3e-16 90.9 Lactobacillaceae Bacteria 1U6XA@1239,2BGTC@1,32ASW@2,3F8NP@33958,4IGRJ@91061 NA|NA|NA FFAGCILK_02760 568703.LGG_01527 4.8e-52 210.3 Lactobacillaceae Bacteria 1VKVE@1239,2ETGD@1,33M08@2,3F708@33958,4HSUY@91061 NA|NA|NA S Phage tail assembly chaperone proteins, TAC FFAGCILK_02761 568703.LGG_01528 6e-109 400.2 Lactobacillaceae Bacteria 1V7ZH@1239,2AZAN@1,31RHY@2,3F4AS@33958,4HJVX@91061 NA|NA|NA S Phage tail tube protein FFAGCILK_02762 568703.LGG_01529 8.1e-53 213.0 Bacilli Bacteria 1VYMN@1239,2FK0I@1,345Z1@2,4HY61@91061 NA|NA|NA S Protein of unknown function (DUF806) FFAGCILK_02763 568703.LGG_01530 6e-65 253.4 Lactobacillaceae Bacteria 1VYI2@1239,2FCMI@1,344QS@2,3F87J@33958,4HYQ6@91061 NA|NA|NA S Bacteriophage HK97-gp10, putative tail-component FFAGCILK_02764 1423732.BALS01000063_gene2224 2.7e-47 194.5 Lactobacillaceae Bacteria 1VJW9@1239,2E799@1,331SU@2,3F8PZ@33958,4HPEE@91061 NA|NA|NA S Phage head-tail joining protein FFAGCILK_02765 1423732.BALS01000063_gene2223 4.2e-28 130.6 Lactobacillaceae Bacteria 1VKP6@1239,2EQC3@1,33HY7@2,3F6YI@33958,4HRKR@91061 NA|NA|NA FFAGCILK_02766 568703.LGG_01533 2.9e-239 834.7 Lactobacillaceae ko:K06904 ko00000 Bacteria 1TSYM@1239,3F5ZB@33958,4HE4V@91061,COG3740@1,COG3740@2,COG4653@1,COG4653@2 NA|NA|NA S Phage capsid family FFAGCILK_02767 568703.LGG_01534 5.4e-198 696.8 Lactobacillaceae Bacteria 1TP8B@1239,3F42D@33958,4HHWD@91061,COG4695@1,COG4695@2 NA|NA|NA S Phage portal protein FFAGCILK_02769 568703.LGG_01535 0.0 1248.4 Lactobacillaceae Bacteria 1TR5W@1239,3FB4K@33958,4HEDC@91061,COG4626@1,COG4626@2 NA|NA|NA S Phage Terminase FFAGCILK_02770 568703.LGG_01536 1.1e-75 289.3 Lactobacillaceae Bacteria 1VW7W@1239,3F43B@33958,4HR5B@91061,COG3747@1,COG3747@2 NA|NA|NA L Phage terminase, small subunit FFAGCILK_02771 386043.lwe1202 8.9e-46 191.0 Listeriaceae 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 1V65N@1239,26MAZ@186820,4HHB0@91061,COG0286@1,COG0286@2 NA|NA|NA V site-specific DNA-methyltransferase (adenine-specific) activity FFAGCILK_02774 568703.LGG_01540 7.4e-60 236.9 Lactobacillaceae Bacteria 1VFKN@1239,3F87W@33958,4HR16@91061,COG1403@1,COG1403@2 NA|NA|NA V HNH nucleases FFAGCILK_02775 1423732.BALS01000055_gene2723 1.1e-60 239.2 Lactobacillaceae ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 1W6SA@1239,3FAGD@33958,4II01@91061,COG0629@1,COG0629@2 NA|NA|NA L Single-strand binding protein family FFAGCILK_02776 568703.LGG_01542 2.9e-31 142.5 Lactobacillaceae Bacteria 1U54N@1239,29NJZ@1,309HY@2,3F4NJ@33958,4IEVV@91061 NA|NA|NA FFAGCILK_02778 63118.O80149_9CAUD 4.3e-11 75.1 Siphoviridae Viruses 4QAIU@10239,4QKM7@10699,4QPDE@28883,4QUQC@35237 NA|NA|NA S HNH endonuclease FFAGCILK_02780 543734.LCABL_19570 4.8e-93 347.1 Bacteria traP GO:0005575,GO:0016020 1.14.99.57,6.2.1.3 ko:K01897,ko:K21481 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria COG2329@1,COG2329@2 NA|NA|NA S heme oxygenase (decyclizing) activity FFAGCILK_02781 543734.LCABL_19580 0.0 1202.6 Lactobacillaceae ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TR2D@1239,3F5VK@33958,4H9SH@91061,COG0577@1,COG0577@2 NA|NA|NA V ABC transporter (permease) FFAGCILK_02782 543734.LCABL_19590 9.7e-138 496.1 Lactobacillaceae bceA ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 M00258,M00314,M00730,M00732,M00737,M00738 ko00000,ko00001,ko00002,ko01504,ko02000 3.A.1,3.A.1.134.3,3.A.1.134.7 Bacteria 1TNZG@1239,3F5FY@33958,4H9UT@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter FFAGCILK_02783 543734.LCABL_19600 5.9e-123 446.8 Lactobacillaceae Bacteria 1TR32@1239,3F5NZ@33958,4HAUJ@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator FFAGCILK_02784 543734.LCABL_19610 5.9e-205 719.9 Lactobacillaceae Bacteria 1TSIC@1239,3FBXD@33958,4HCB6@91061,COG0642@1,COG2205@2 NA|NA|NA T PhoQ Sensor FFAGCILK_02785 543734.LCABL_19620 6.4e-110 403.3 Lactobacillaceae nrdG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0031250,GO:0032991,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 1.97.1.4 ko:K04068 R04710 ko00000,ko01000 iE2348C_1286.E2348C_4563 Bacteria 1V1HG@1239,3F46H@33958,4HGJ9@91061,COG0602@1,COG0602@2 NA|NA|NA O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine FFAGCILK_02786 543734.LCABL_19630 0.0 1295.4 Lactobacillaceae copB 3.6.3.4 ko:K01533 R00086 RC00002 ko00000,ko01000 3.A.3.5 Bacteria 1TP5S@1239,3F4IX@33958,4HAI0@91061,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase FFAGCILK_02787 543734.LCABL_19640 7.9e-76 289.7 Lactobacillaceae copR Bacteria 1VA7Q@1239,3F7D0@33958,4HKGF@91061,COG3682@1,COG3682@2 NA|NA|NA K Copper transport repressor CopY TcrY FFAGCILK_02788 543734.LCABL_19650 6.2e-235 819.7 Lactobacillaceae purD 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS05245,iYO844.BSU06530 Bacteria 1UHN9@1239,3F4Z8@33958,4HA70@91061,COG0151@1,COG0151@2 NA|NA|NA F Belongs to the GARS family FFAGCILK_02789 543734.LCABL_19660 9.1e-289 998.8 Lactobacillaceae purH GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 iJN678.purH Bacteria 1TPQ5@1239,3F4FD@33958,4H9YY@91061,COG0138@1,COG0138@2 NA|NA|NA F Bifunctional purine biosynthesis protein PurH FFAGCILK_02790 543734.LCABL_19670 1.5e-98 365.5 Lactobacillaceae purN 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3RJ@1239,3F3UN@33958,4HGY5@91061,COG0299@1,COG0299@2 NA|NA|NA F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate FFAGCILK_02791 543734.LCABL_19680 2e-183 648.3 Lactobacillaceae purM GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 ko:K01933,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04208 RC00090,RC00166,RC01100 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1844,iECSF_1327.ECSF_2340 Bacteria 1TP9J@1239,3F4RT@33958,4HABW@91061,COG0150@1,COG0150@2 NA|NA|NA F Phosphoribosylformylglycinamidine cyclo-ligase FFAGCILK_02792 543734.LCABL_19690 7.6e-277 959.1 Lactobacillaceae purF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 iSB619.SA_RS05225 Bacteria 1TPH3@1239,3F3U7@33958,4HAXU@91061,COG0034@1,COG0034@2 NA|NA|NA F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine FFAGCILK_02793 543734.LCABL_19700 0.0 1451.8 Lactobacillaceae purL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPAS@1239,3F4IQ@33958,4HB3N@91061,COG0046@1,COG0046@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL FFAGCILK_02794 543734.LCABL_19710 2.8e-128 464.5 Lactobacillaceae purQ GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP1B@1239,3F48D@33958,4HAKZ@91061,COG0047@1,COG0047@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL FFAGCILK_02795 543734.LCABL_19720 6.4e-41 172.9 Lactobacillaceae purS 6.3.2.6,6.3.5.3 ko:K01923,ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463,R04591 RC00010,RC00064,RC00162,RC01160 ko00000,ko00001,ko00002,ko01000 iYO844.BSU06460 Bacteria 1VEH1@1239,3F81F@33958,4HP0E@91061,COG1828@1,COG1828@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL FFAGCILK_02796 543734.LCABL_19730 8e-134 483.0 Lactobacillaceae purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016881,GO:0044424,GO:0044444,GO:0044464 4.1.1.21,4.3.2.2,6.3.2.6 ko:K01587,ko:K01756,ko:K01923 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04209,R04559,R04591 RC00064,RC00162,RC00379,RC00444,RC00445,RC00590 ko00000,ko00001,ko00002,ko01000 iAF1260.b2476,iB21_1397.B21_02330,iBWG_1329.BWG_2240,iE2348C_1286.E2348C_2713,iEC042_1314.EC042_2677,iEC55989_1330.EC55989_2759,iECABU_c1320.ECABU_c27880,iECBD_1354.ECBD_1213,iECB_1328.ECB_02368,iECDH10B_1368.ECDH10B_2642,iECDH1ME8569_1439.ECDH1ME8569_2402,iECDH1ME8569_1439.EcDH1_1193,iECD_1391.ECD_02368,iECED1_1282.ECED1_2911,iECH74115_1262.ECH74115_3698,iECIAI1_1343.ECIAI1_2527,iECNA114_1301.ECNA114_2561,iECO103_1326.ECO103_2988,iECO111_1330.ECO111_3199,iECO26_1355.ECO26_3522,iECOK1_1307.ECOK1_2784,iECP_1309.ECP_2490,iECS88_1305.ECS88_2658,iECSE_1348.ECSE_2760,iECSF_1327.ECSF_2329,iECSP_1301.ECSP_3415,iECUMN_1333.ECUMN_2789,iECW_1372.ECW_m2698,iECs_1301.ECs3338,iEKO11_1354.EKO11_1259,iETEC_1333.ETEC_2581,iEcDH1_1363.EcDH1_1193,iEcE24377_1341.EcE24377A_2757,iEcHS_1320.EcHS_A2607,iEcSMS35_1347.EcSMS35_2623,iEcolC_1368.EcolC_1200,iG2583_1286.G2583_2999,iJN746.PP_1240,iJO1366.b2476,iJR904.b2476,iLF82_1304.LF82_1775,iNRG857_1313.NRG857_12360,iSFV_1184.SFV_2521,iSF_1195.SF2519,iSFxv_1172.SFxv_2773,iS_1188.S2669,iSbBS512_1146.SbBS512_E2848,iUMNK88_1353.UMNK88_3071,iWFL_1372.ECW_m2698,iY75_1357.Y75_RS12925,iYL1228.KPN_02810,iZ_1308.Z3735 Bacteria 1TP11@1239,3F44Z@33958,4H9U8@91061,COG0152@1,COG0152@2 NA|NA|NA F Belongs to the SAICAR synthetase family FFAGCILK_02797 543734.LCABL_19740 7.8e-213 746.1 Lactobacillaceae purK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQCD@1239,3F3YV@33958,4H9M5@91061,COG0026@1,COG0026@2 NA|NA|NA F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) FFAGCILK_02798 543734.LCABL_19750 3.2e-78 297.7 Lactobacillaceae purE GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 iETEC_1333.ETEC_0575,iJN746.PP_5336,iPC815.YPO3076,iUTI89_1310.UTI89_C0551 Bacteria 1V1MV@1239,3F6P0@33958,4HFR7@91061,COG0041@1,COG0041@2 NA|NA|NA F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) FFAGCILK_02799 543734.LCABL_19760 4.7e-103 380.6 Lactobacillaceae thiT ko:K16789 ko00000,ko02000 2.A.88.3 Bacteria 1V6YE@1239,3F738@33958,4HIJE@91061,COG3859@1,COG3859@2 NA|NA|NA S Thiamine transporter protein (Thia_YuaJ) FFAGCILK_02800 543734.LCABL_19770 3.8e-257 893.6 Lactobacillaceae iolT ko:K06609 ko00000,ko02000 2.A.1.1.26 Bacteria 1TREV@1239,3F3ZS@33958,4HAN1@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily FFAGCILK_02801 543734.LCABL_19780 0.0 1113.2 Lactobacillaceae ptsI GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0008150,GO:0008643,GO:0008965,GO:0009401,GO:0016740,GO:0016772,GO:0016775,GO:0019197,GO:0032991,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 8.A.7 iB21_1397.B21_02277,iE2348C_1286.E2348C_2602,iEC042_1314.EC042_2625,iECBD_1354.ECBD_1265,iECB_1328.ECB_02316,iECD_1391.ECD_02316,iECH74115_1262.ECH74115_3647,iECIAI1_1343.ECIAI1_2474,iECIAI39_1322.ECIAI39_2562,iECO103_1326.ECO103_2935,iECO111_1330.ECO111_3146,iECO26_1355.ECO26_3469,iECP_1309.ECP_2440,iECSE_1348.ECSE_2707,iECSP_1301.ECSP_3364,iECUMN_1333.ECUMN_2738,iECW_1372.ECW_m2645,iECs_1301.ECs3288,iEKO11_1354.EKO11_1312,iEcE24377_1341.EcE24377A_2703,iEcHS_1320.EcHS_A2551,iEcSMS35_1347.EcSMS35_2571,iEcolC_1368.EcolC_1262,iLF82_1304.LF82_1770,iNRG857_1313.NRG857_12115,iSBO_1134.SBO_2440,iSDY_1059.SDY_2613,iSFV_1184.SFV_2468,iSF_1195.SF2471,iSFxv_1172.SFxv_2720,iSSON_1240.SSON_2505,iS_1188.S2617,iUMNK88_1353.UMNK88_3018,iWFL_1372.ECW_m2645,iZ_1308.Z3682 Bacteria 1TPK8@1239,3F3MS@33958,4H9VD@91061,COG1080@1,COG1080@2 NA|NA|NA G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) FFAGCILK_02802 1423732.BALS01000007_gene584 2.7e-39 167.5 Lactobacillaceae ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007 ko:K11189 ko00000,ko02000 4.A.2.1 Bacteria 1VA0R@1239,3F6XQ@33958,4HKGA@91061,COG1925@1,COG1925@2 NA|NA|NA G phosphocarrier protein HPR FFAGCILK_02803 1423816.BACQ01000003_gene57 5.9e-28 129.4 Firmicutes Bacteria 1VKXC@1239,2EI19@1,33BSS@2 NA|NA|NA FFAGCILK_02804 543734.LCABL_19810 0.0 1093.2 Lactobacillaceae clpE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03697 ko00000,ko03110 Bacteria 1TPMU@1239,3F3K9@33958,4HA0V@91061,COG0542@1,COG0542@2 NA|NA|NA O Belongs to the ClpA ClpB family FFAGCILK_02805 543734.LCABL_19820 2.8e-45 187.6 Lactobacillaceae XK27_09445 Bacteria 1VFRS@1239,2EBZ8@1,335YI@2,3F70G@33958,4HNUK@91061 NA|NA|NA S Domain of unknown function (DUF1827) FFAGCILK_02807 543734.LCABL_19840 1.3e-306 1058.1 Lactobacillaceae prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02837,ko:K07133 ko00000,ko03012 Bacteria 1TPYT@1239,3F489@33958,4HADS@91061,COG4108@1,COG4108@2 NA|NA|NA J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP FFAGCILK_02808 543734.LCABL_19850 2.5e-245 854.4 Lactobacillaceae hlyX ko:K03699 ko00000,ko02042 Bacteria 1TPN0@1239,3F3KG@33958,4H9SB@91061,COG1253@1,COG1253@2 NA|NA|NA S Transporter associated domain FFAGCILK_02809 543734.LCABL_19860 4.1e-196 690.6 Lactobacillaceae yueF GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 Bacteria 1TQ84@1239,3F418@33958,4H9SR@91061,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter FFAGCILK_02810 543734.LCABL_19870 6.2e-73 280.0 Lactobacillaceae ko:K02348 ko00000 Bacteria 1VA2J@1239,3F6HQ@33958,4HKF5@91061,COG2153@1,COG2153@2 NA|NA|NA S Acetyltransferase (GNAT) domain FFAGCILK_02811 543734.LCABL_19880 4e-95 354.0 Lactobacillaceae Bacteria 1U6J7@1239,29NVN@1,30AEE@2,3F80T@33958,4IGBR@91061 NA|NA|NA FFAGCILK_02812 543734.LCABL_19890 2.2e-104 384.8 Lactobacillaceae ygaC ko:K07586 ko00000 Bacteria 1TRX8@1239,3F48S@33958,4H9NM@91061,COG3557@1,COG3557@2 NA|NA|NA J Belongs to the UPF0374 family FFAGCILK_02813 543734.LCABL_19900 6.7e-142 510.0 Lactobacillaceae recX GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019899,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496 2.4.1.337 ko:K03565,ko:K19002 ko00561,ko01100,map00561,map01100 R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003,ko03400 GT4 Bacteria 1V72V@1239,3F4BY@33958,4HJ7R@91061,COG2137@1,COG2137@2 NA|NA|NA S Regulatory protein RecX FFAGCILK_02814 543734.LCABL_19910 9.7e-183 646.0 Bacteria frvR GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 ko:K02538,ko:K03483,ko:K09685,ko:K18531 ko00000,ko03000 Bacteria COG3711@1,COG3711@2 NA|NA|NA K transcriptional antiterminator FFAGCILK_02815 543734.LCABL_19910 2.2e-102 378.3 Bacteria frvR GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 ko:K02538,ko:K03483,ko:K09685,ko:K18531 ko00000,ko03000 Bacteria COG3711@1,COG3711@2 NA|NA|NA K transcriptional antiterminator FFAGCILK_02816 543734.LCABL_19920 1.9e-62 245.0 Lactobacillaceae Bacteria 1U7J8@1239,29Q60@1,30B4X@2,3F9T1@33958,4IHG5@91061 NA|NA|NA FFAGCILK_02817 543734.LCABL_19940 6.1e-252 876.3 Lactobacillaceae rumA 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 ko00000,ko01000,ko03009,ko03016 Bacteria 1TP4H@1239,3F4GQ@33958,4HA6M@91061,COG2265@1,COG2265@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family FFAGCILK_02818 543734.LCABL_19950 8.2e-79 299.7 Lactobacillaceae Bacteria 1V3SN@1239,3F6KR@33958,4HH4T@91061,COG3613@1,COG3613@2 NA|NA|NA F Nucleoside 2-deoxyribosyltransferase FFAGCILK_02819 543734.LCABL_19960 1.8e-133 481.9 Lactobacillaceae GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 ko:K03489 ko00000,ko03000 Bacteria 1V4DC@1239,3F6TC@33958,4HIDU@91061,COG2188@1,COG2188@2 NA|NA|NA K UTRA FFAGCILK_02820 543734.LCABL_19970 3.5e-290 1003.4 Lactobacillaceae celA 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 GT1 Bacteria 1TP19@1239,3F3PQ@33958,4HA1W@91061,COG2723@1,COG2723@2 NA|NA|NA G Belongs to the glycosyl hydrolase 1 family FFAGCILK_02821 543734.LCABL_19980 9.4e-253 879.0 Lactobacillaceae celD GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016310,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0071704 2.7.1.207 ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 M00275,M00281 R04393,R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.1,4.A.3.2 Bacteria 1TP8D@1239,3FC70@33958,4HDVN@91061,COG1455@1,COG1455@2 NA|NA|NA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane FFAGCILK_02822 543734.LCABL_19990 6.1e-85 320.1 Lactobacillaceae Bacteria 1VE22@1239,2E5MG@1,330CD@2,3FBP1@33958,4IRFH@91061 NA|NA|NA FFAGCILK_02823 543734.LCABL_20000 2e-49 201.4 Lactobacillaceae chbA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0009987,GO:0015144,GO:0016043,GO:0016740,GO:0016772,GO:0016773,GO:0022607,GO:0022804,GO:0022857,GO:0034219,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0071702,GO:0071840,GO:0090563,GO:0090566,GO:1901264,GO:1902815 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 iECABU_c1320.ECABU_c17610,iECOK1_1307.ECOK1_1683,iECUMN_1333.ECUMN_2025,iNRG857_1313.NRG857_07575,iUMN146_1321.UM146_09345 Bacteria 1VEGE@1239,3FA2W@33958,4HM37@91061,COG1447@1,COG1447@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIA subunit FFAGCILK_02824 543734.LCABL_20010 6.9e-50 203.0 Lactobacillaceae 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 Bacteria 1VADE@1239,3F7XZ@33958,4HKG9@91061,COG1440@1,COG1440@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit FFAGCILK_02825 543734.LCABL_20020 0.0 1175.6 Lactobacillaceae poxB 1.2.3.3,1.2.5.1 ko:K00156,ko:K00158 ko00620,ko01100,map00620,map01100 R00207,R03145 RC00860,RC02745 ko00000,ko00001,ko01000 Bacteria 1TQE8@1239,3F3R9@33958,4HBUS@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family FFAGCILK_02826 543734.LCABL_20030 4.5e-219 766.9 Lactobacillaceae mvaS 2.3.3.10 ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 M00088,M00095 R01978 RC00004,RC00503 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR4K@1239,3F425@33958,4HA67@91061,COG3425@1,COG3425@2 NA|NA|NA I Hydroxymethylglutaryl-CoA synthase FFAGCILK_02827 543734.LCABL_20040 3.2e-202 711.1 Lactobacillaceae mvaA 1.1.1.34,1.1.1.88 ko:K00021,ko:K00054 ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00900,map01100,map01110,map01130,map04152,map04976 M00095 R02081,R02082 RC00004,RC00644 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPNY@1239,3F3YY@33958,4HBQ3@91061,COG1257@1,COG1257@2 NA|NA|NA C Belongs to the HMG-CoA reductase family FFAGCILK_02828 543734.LCABL_20050 1e-207 729.2 Lactobacillaceae atoB 1.1.1.88,2.3.1.9 ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TP07@1239,3F3Q5@33958,4H9RJ@91061,COG0183@1,COG0183@2 NA|NA|NA I Belongs to the thiolase family FFAGCILK_02829 543734.LCABL_20060 1.6e-48 198.4 Lactobacillaceae Bacteria 1U6HZ@1239,2B6X8@1,31ZX5@2,3F7YC@33958,4IGAA@91061 NA|NA|NA FFAGCILK_02830 543734.LCABL_20070 1.1e-160 572.4 Lactobacillaceae 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 GH20 Bacteria 1VSC9@1239,3F4RS@33958,4HUQI@91061,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase domain protein TIM barrel FFAGCILK_02831 543734.LCABL_20080 2.4e-101 374.8 Lactobacillaceae ko:K07448 ko00000,ko02048 Bacteria 1VBYF@1239,3F8C4@33958,4HM6M@91061,COG1787@1,COG1787@2 NA|NA|NA V Restriction endonuclease FFAGCILK_02832 543734.LCABL_20090 2.6e-157 561.2 Bacteria 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria COG2017@1,COG2017@2 NA|NA|NA G converts alpha-aldose to the beta-anomer FFAGCILK_02833 543734.LCABL_20100 5.2e-212 743.4 Lactobacillaceae argE 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPMJ@1239,3F3N9@33958,4HB39@91061,COG0624@1,COG0624@2 NA|NA|NA E succinyl-diaminopimelate desuccinylase FFAGCILK_02834 543734.LCABL_20110 1e-102 379.4 Lactobacillaceae Bacteria 1VB4T@1239,3F497@33958,4HMUC@91061,COG4684@1,COG4684@2 NA|NA|NA S ECF transporter, substrate-specific component FFAGCILK_02836 543734.LCABL_20130 2.1e-79 301.6 Firmicutes yodP 2.3.1.264 ko:K21935 R11701 ko00000,ko01000 Bacteria 1VEF8@1239,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase GNAT Family FFAGCILK_02837 543734.LCABL_20140 1.1e-85 322.4 Lactobacillaceae ydcK ko:K03095 ko00000 Bacteria 1V6NU@1239,3F703@33958,4HIHY@91061,COG3091@1,COG3091@2 NA|NA|NA S Belongs to the SprT family FFAGCILK_02838 543734.LCABL_20150 5.6e-130 470.3 Lactobacillaceae XK27_08845 ko:K05833 M00247 ko00000,ko00002,ko02000 Bacteria 1TPAN@1239,3F3NW@33958,4HCHC@91061,COG1101@1,COG1101@2 NA|NA|NA S ABC transporter, ATP-binding protein FFAGCILK_02839 543734.LCABL_20160 7.1e-140 503.4 Lactobacillaceae XK27_08840 ko:K05832 M00247 ko00000,ko00002,ko02000 Bacteria 1TPDJ@1239,3F40J@33958,4HBMY@91061,COG4120@1,COG4120@2 NA|NA|NA U Belongs to the binding-protein-dependent transport system permease family FFAGCILK_02840 568703.LGG_01853 3e-155 554.7 Lactobacillaceae XK27_08835 ko:K01989,ko:K05832 M00247 ko00000,ko00002,ko02000 Bacteria 1TPB0@1239,3F462@33958,4HESK@91061,COG2984@1,COG2984@2 NA|NA|NA S ABC transporter FFAGCILK_02842 543734.LCABL_20210 9e-72 276.2 Lactobacillaceae ko:K02029,ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1VFU9@1239,2E7AN@1,331U3@2,3FBB1@33958,4HY33@91061 NA|NA|NA FFAGCILK_02843 543734.LCABL_20220 0.0 1677.5 Lactobacillaceae pacL 3.6.3.8 ko:K01537 ko00000,ko01000 3.A.3.2 Bacteria 1TPF5@1239,3F3KP@33958,4H9S5@91061,COG0474@1,COG0474@2 NA|NA|NA P P-type ATPase FFAGCILK_02844 543734.LCABL_20230 1e-215 755.7 Lactobacillaceae Bacteria 1V0GX@1239,3F4TH@33958,4HCXH@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase FFAGCILK_02845 543734.LCABL_20240 5.7e-152 543.5 Lactobacillaceae nadE GO:0003674,GO:0003824,GO:0003952,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0033554,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_1910,iECW_1372.ECW_m1909,iEKO11_1354.EKO11_2035,iETEC_1333.ETEC_1772,iEcE24377_1341.EcE24377A_1961,iSFV_1184.SFV_1480,iSF_1195.SF1486,iSFxv_1172.SFxv_1676,iSSON_1240.SSON_1418,iS_1188.S1603,iWFL_1372.ECW_m1909 Bacteria 1TQ38@1239,3F43Z@33958,4HA2R@91061,COG0171@1,COG0171@2 NA|NA|NA F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source FFAGCILK_02846 543734.LCABL_20250 2.3e-218 764.6 Lactobacillaceae Bacteria 1V0GX@1239,3F4TH@33958,4HCXH@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase FFAGCILK_02847 543734.LCABL_20260 7.2e-275 952.6 Lactobacillaceae pncB GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 R01724 RC00033 ko00000,ko00001,ko01000 iYO844.BSU31750 Bacteria 1TPDW@1239,3F3K7@33958,4HAI4@91061,COG1488@1,COG1488@2 NA|NA|NA F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP FFAGCILK_02848 543734.LCABL_20270 5e-125 453.8 Lactobacillaceae gntR1 ko:K03710,ko:K11922 ko00000,ko03000 Bacteria 1UYBW@1239,3F4D0@33958,4HDDG@91061,COG2188@1,COG2188@2 NA|NA|NA K UbiC transcription regulator-associated domain protein FFAGCILK_02849 543734.LCABL_20280 2.2e-218 764.6 Lactobacillaceae nagA GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046348,GO:0046872,GO:0046914,GO:0046983,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 R02059 RC00166,RC00300 ko00000,ko00001,ko01000 Bacteria 1TPFK@1239,3F40F@33958,4HC6C@91061,COG1820@1,COG1820@2 NA|NA|NA G Belongs to the metallo-dependent hydrolases superfamily. NagA family FFAGCILK_02850 543734.LCABL_20290 1.7e-137 495.4 Lactobacillaceae proC 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP1E@1239,3F4SE@33958,4H9RV@91061,COG0345@1,COG0345@2 NA|NA|NA E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline FFAGCILK_02851 543734.LCABL_20300 0.0 1368.6 Lactobacillaceae yuxL 3.4.19.1 ko:K01303 ko00000,ko01000,ko01002 Bacteria 1TR2N@1239,3F59I@33958,4H9RR@91061,COG1506@1,COG1506@2 NA|NA|NA E Prolyl oligopeptidase family FFAGCILK_02854 543734.LCABL_20330 1.1e-158 565.8 Lactobacillaceae yjjH Bacteria 1VHY9@1239,3F3SW@33958,4HPAR@91061,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase FFAGCILK_02855 543734.LCABL_20340 4.6e-266 923.3 Lactobacillaceae dtpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03305 ko00000 2.A.17 Bacteria 1TP81@1239,3F4WU@33958,4HAF2@91061,COG3104@1,COG3104@2 NA|NA|NA U amino acid peptide transporter FFAGCILK_02856 543734.LCABL_20350 0.0 1438.7 Lactobacillaceae macB_3 ko:K02003,ko:K02004,ko:K05685 ko02010,map02010 M00258,M00709 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.122.1,3.A.1.122.12 Bacteria 1TPBJ@1239,3F44P@33958,4HBK7@91061,COG0577@1,COG0577@2,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein FFAGCILK_02857 543734.LCABL_20360 1.1e-65 255.8 Lactobacillaceae Bacteria 1U666@1239,29P63@1,30A48@2,3F75Z@33958,4IFWC@91061 NA|NA|NA FFAGCILK_02858 543734.LCABL_20370 3.4e-76 290.8 Lactobacillaceae Bacteria 1U6ZG@1239,29PS8@1,30AQG@2,3F8RT@33958,4IGTR@91061 NA|NA|NA S function, without similarity to other proteins FFAGCILK_02859 543734.LCABL_20380 1.9e-264 917.9 Firmicutes ko:K03292,ko:K16248 ko00000,ko02000 2.A.2 Bacteria 1TS1S@1239,COG2211@1,COG2211@2 NA|NA|NA G MFS/sugar transport protein FFAGCILK_02860 543734.LCABL_20390 5.5e-230 803.1 Lactobacillaceae alfA 3.2.1.51 ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 GH29 Bacteria 1UYIM@1239,3F5S7@33958,4HJ46@91061,COG3669@1,COG3669@2 NA|NA|NA G Alpha-L-fucosidase FFAGCILK_02861 543734.LCABL_20400 5.4e-58 229.9 Lactobacillaceae Bacteria 1U8JK@1239,29MVS@1,308TH@2,3FB21@33958,4IIHJ@91061 NA|NA|NA FFAGCILK_02862 543734.LCABL_20410 0.0 1108.6 Lactobacillaceae pckG GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007028,GO:0007154,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009267,GO:0009410,GO:0009605,GO:0009607,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010106,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016020,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019725,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030003,GO:0030145,GO:0030154,GO:0030312,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031668,GO:0031669,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033554,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042592,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0046916,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0048878,GO:0050789,GO:0050792,GO:0050794,GO:0050801,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0065008,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071496,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0071944,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0075136,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:0098771,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32,4.1.1.49 ko:K01596,ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964 M00003,M00170 R00341,R00431,R00726 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2638 Bacteria 1UIM9@1239,3FBXE@33958,4HED4@91061,COG1274@1,COG1274@2 NA|NA|NA C Phosphoenolpyruvate carboxykinase FFAGCILK_02863 568703.LGG_01877 1.4e-17 94.7 Lactobacillaceae Bacteria 1U802@1239,2BP56@1,32HW1@2,3FADE@33958,4IHXF@91061 NA|NA|NA S Virus attachment protein p12 family FFAGCILK_02864 543734.LCABL_20430 0.0 1354.7 Lactobacillaceae feoB ko:K04759 ko00000,ko02000 9.A.8.1 Bacteria 1TP7E@1239,3F553@33958,4HBCS@91061,COG0370@1,COG0370@2 NA|NA|NA P transporter of a GTP-driven Fe(2 ) uptake system FFAGCILK_02865 543734.LCABL_20440 2.2e-41 174.5 Lactobacillaceae feoA ko:K04758 ko00000,ko02000 Bacteria 1VEHC@1239,3F729@33958,4HPFS@91061,COG1918@1,COG1918@2 NA|NA|NA P FeoA FFAGCILK_02866 1423732.BALS01000053_gene2768 9.9e-17 92.0 Lactobacillaceae feoA ko:K04758 ko00000,ko02000 Bacteria 1VFH1@1239,3FBMK@33958,4HMT6@91061,COG1918@1,COG1918@2 NA|NA|NA P FeoA FFAGCILK_02867 543734.LCABL_20460 3.3e-122 444.5 Lactobacillaceae Bacteria 1UI5G@1239,3F6R2@33958,4ISEF@91061,COG2755@1,COG2755@2 NA|NA|NA E lipolytic protein G-D-S-L family FFAGCILK_02870 543734.LCABL_20490 3.5e-117 427.6 Lactobacillaceae ywnB ko:K07118 ko00000 Bacteria 1TZ3T@1239,3F5K7@33958,4HVUN@91061,COG2910@1,COG2910@2 NA|NA|NA S NAD(P)H-binding FFAGCILK_02871 1423732.BALS01000053_gene2773 1.7e-61 242.3 Lactobacillaceae Bacteria 1U7EP@1239,29Q3J@1,30B27@2,3F9HJ@33958,4IHAJ@91061 NA|NA|NA S MucBP domain FFAGCILK_02872 543734.LCABL_20510 1.2e-62 246.1 Lactobacillaceae Bacteria 1U6BM@1239,29PA5@1,30A8A@2,3F7J0@33958,4IG39@91061 NA|NA|NA FFAGCILK_02876 543734.LCABL_13470 8.3e-213 746.1 Lactobacillaceae GO:0008150,GO:0009405,GO:0044419,GO:0051704 ko:K02656,ko:K07273,ko:K14196 ko05150,map05150 ko00000,ko00001,ko02035,ko02044 Bacteria 1V16P@1239,3FC13@33958,4HF99@91061,COG1388@1,COG1388@2,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 FFAGCILK_02877 1423732.BALS01000111_gene29 5.2e-67 260.4 Lactobacillaceae Bacteria 1W0SS@1239,2FDCN@1,345EF@2,3F8B6@33958,4HXYE@91061 NA|NA|NA S Bacteriophage holin of superfamily 6 (Holin_LLH) FFAGCILK_02879 543734.LCABL_11250 7.9e-64 249.6 Lactobacillaceae Bacteria 1U6QN@1239,2DKRR@1,30AIG@2,3F8BB@33958,4IGHX@91061 NA|NA|NA FFAGCILK_02882 568703.LGG_01139 2.3e-179 636.3 Bacilli Bacteria 1TTBV@1239,4HBWT@91061,COG4926@1,COG4926@2 NA|NA|NA S cellulase activity FFAGCILK_02883 39103.U5U775_9CAUD 4.4e-147 528.5 Siphoviridae Viruses 4QKN2@10699 NA|NA|NA S Phage tail protein FFAGCILK_02884 51369.Q9T0X1_9CAUD 0.0 1298.9 Siphoviridae GO:0008150,GO:0016032,GO:0019058,GO:0019068,GO:0044403,GO:0044419,GO:0051704,GO:0098003 Viruses 4QAK6@10239,4QKKV@10699,4QPBY@28883,4QUP9@35237 NA|NA|NA S peptidoglycan catabolic process FFAGCILK_02885 1231336.L248_1700 1.8e-21 109.0 Lactobacillaceae Bacteria 1U768@1239,29PXI@1,30AVX@2,3F912@33958,4IH0Z@91061 NA|NA|NA FFAGCILK_02886 947980.E9LUI9_9CAUD 2.5e-72 278.5 Siphoviridae Viruses 4QAYN@10239,4QKPS@10699,4QPCU@28883,4QUR7@35237 NA|NA|NA S Pfam:Phage_TTP_1 FFAGCILK_02887 1231336.L248_1697 7.5e-30 136.7 Lactobacillaceae Bacteria 1U6G0@1239,29PDS@1,30ABY@2,3F7U0@33958,4IG81@91061 NA|NA|NA FFAGCILK_02888 39103.U5U769_9CAUD 8.5e-66 256.1 Siphoviridae Viruses 4QB1F@10239,4QKPW@10699,4QPSW@28883,4QUYH@35237 NA|NA|NA S exonuclease activity FFAGCILK_02889 1231336.L248_1695 4e-40 170.6 Lactobacillaceae Bacteria 1U6TU@1239,2DKS7@1,30AKM@2,3F8H9@33958,4IGMN@91061 NA|NA|NA S Phage head-tail joining protein FFAGCILK_02890 1231336.L248_1694 1.9e-27 128.6 Lactobacillaceae Bacteria 1U6JX@1239,2EEUA@1,30AEZ@2,3F824@33958,4IGCG@91061 NA|NA|NA S Phage gp6-like head-tail connector protein FFAGCILK_02891 39103.U5U4N8_9CAUD 3.3e-20 104.0 Siphoviridae Viruses 4QAK6@10239,4QKP8@10699,4QPBY@28883,4QUP9@35237 NA|NA|NA S peptidase activity FFAGCILK_02892 39103.U5U4N8_9CAUD 8.4e-205 719.5 Siphoviridae Viruses 4QAK6@10239,4QKP8@10699,4QPBY@28883,4QUP9@35237 NA|NA|NA S peptidase activity FFAGCILK_02893 51369.Q8LTC1_9CAUD 2.3e-113 414.8 Siphoviridae GO:0003674,GO:0003824,GO:0005575,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019012,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 Viruses 4QAK6@10239,4QKP8@10699,4QPBY@28883,4QUP9@35237 NA|NA|NA S peptidase activity FFAGCILK_02894 39103.U5U764_9CAUD 3.7e-235 820.5 Siphoviridae Viruses 4QAYV@10239,4QKKX@10699,4QPU3@28883,4QUZ7@35237 NA|NA|NA S Phage portal protein FFAGCILK_02896 51369.Q8LTC3_9CAUD 0.0 1137.5 Siphoviridae Viruses 4QBV3@10239,4QKW5@10699,4QPPJ@28883,4QW0W@35237 NA|NA|NA S Phage Terminase FFAGCILK_02897 39103.U5U3Z1_9CAUD 9.6e-77 292.7 Caudovirales Viruses 4QBS6@10239,4QPP2@28883,4QUNW@35237 NA|NA|NA S Phage terminase, small subunit FFAGCILK_02898 349123.Lreu23DRAFT_3876 4.6e-74 284.6 Lactobacillaceae ko:K06877,ko:K07451 ko00000,ko01000,ko02048 Bacteria 1VQIP@1239,3F6KP@33958,4HM74@91061,COG1403@1,COG1403@2 NA|NA|NA L HNH nucleases FFAGCILK_02899 1423732.BALS01000107_gene440 1.4e-27 129.8 Lactobacillaceae Bacteria 1U7RW@1239,29QA8@1,30B9C@2,3FA3A@33958,4IHP8@91061 NA|NA|NA FFAGCILK_02901 39103.U5U741_9CAUD 9.9e-44 182.6 Caudovirales Viruses 4QES5@10239,4QQQF@28883,4QWZ4@35237 NA|NA|NA FFAGCILK_02902 51369.Q8LTA0_9CAUD 1.9e-63 248.8 Siphoviridae Viruses 4QAIU@10239,4QKM7@10699,4QPDE@28883,4QUQC@35237 NA|NA|NA S HNH endonuclease FFAGCILK_02903 1423732.BALS01000107_gene442 6.3e-218 763.1 Lactobacillaceae Bacteria 1VGE5@1239,2C1BV@1,32ZTD@2,3F9J1@33958,4HPF9@91061 NA|NA|NA S GcrA cell cycle regulator FFAGCILK_02906 543734.LCABL_05720 3.1e-51 208.0 Bacilli Bacteria 1W51N@1239,2DCNS@1,2ZESF@2,4I1NU@91061 NA|NA|NA FFAGCILK_02909 39103.U5U4M8_9CAUD 2.6e-73 281.2 Caudovirales Viruses 4QAXV@10239,4QPCP@28883,4QV7S@35237 NA|NA|NA S YopX protein FFAGCILK_02911 568703.LGG_01114 9.8e-22 108.6 Lactobacillaceae Bacteria 1U8C8@1239,29QN8@1,30BMV@2,3FATU@33958,4IIA7@91061 NA|NA|NA FFAGCILK_02912 1423732.BALS01000058_gene2829 2.7e-57 227.6 Lactobacillaceae Bacteria 1VA3C@1239,2DJ23@1,32UC6@2,3F7VB@33958,4HPYG@91061 NA|NA|NA S VRR_NUC FFAGCILK_02914 51369.Q9T0Y1_9CAUD 0.0 1558.1 Siphoviridae GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016032,GO:0016070,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0018130,GO:0019058,GO:0019079,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0039693,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044403,GO:0044419,GO:0046483,GO:0051704,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 Viruses 4QAY9@10239,4QKV1@10699,4QPAN@28883,4QV7W@35237 NA|NA|NA S hydrolase activity FFAGCILK_02915 1423732.BALS01000058_gene2826 3.7e-99 367.5 Lactobacillaceae Bacteria 1VATD@1239,2CTNW@1,32STT@2,3F56X@33958,4HPYZ@91061 NA|NA|NA S Protein of unknown function (DUF669) FFAGCILK_02916 51369.Q9T0Y3_9CAUD 4.4e-258 896.7 Siphoviridae Viruses 4QB5I@10239,4QKRP@10699,4QPQ9@28883,4QUT2@35237 NA|NA|NA S helicase activity FFAGCILK_02917 51369.Q9T0Y5_9CAUD 7.7e-129 466.5 Siphoviridae Viruses 4QF8S@10239,4QN9W@10699,4QPVZ@28883,4QVW8@35237 NA|NA|NA S AAA domain FFAGCILK_02918 146269.A8YQL4_9CAUD 3.1e-81 307.8 Viruses Viruses 4QBBN@10239 NA|NA|NA S Siphovirus Gp157 FFAGCILK_02924 1423732.BALS01000058_gene2819 9.4e-92 342.8 Bacilli Bacteria 1VH17@1239,2E3D0@1,32YC9@2,4HQ0Y@91061 NA|NA|NA FFAGCILK_02925 1423732.BALS01000058_gene2818 1.2e-42 178.7 Lactobacillaceae Bacteria 1U7TH@1239,29QB8@1,30BAG@2,3FA5K@33958,4IHQZ@91061 NA|NA|NA FFAGCILK_02926 1423732.BALS01000058_gene2817 2.8e-134 484.6 Bacilli ko:K07741 ko00000 Bacteria 1VGZA@1239,4HVM2@91061,COG3561@1,COG3561@2 NA|NA|NA K AntA/AntB antirepressor FFAGCILK_02927 349123.Lreu23DRAFT_3080 2.6e-13 80.9 Bacilli Bacteria 1VMFQ@1239,4HSBC@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins FFAGCILK_02928 349123.Lreu23DRAFT_4239 1.6e-23 115.5 Firmicutes Bacteria 1VKKH@1239,COG1396@1,COG1396@2 NA|NA|NA K Transcriptional regulator, Cro CI family FFAGCILK_02929 908339.HMPREF9265_1644 1.1e-16 94.7 Bacteria Bacteria COG2856@1,COG2856@2 NA|NA|NA E Zn peptidase FFAGCILK_02931 1423816.BACQ01000031_gene1347 2.1e-113 416.0 Bacilli Z012_01130 Bacteria 1UZBJ@1239,4HI73@91061,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family FFAGCILK_02932 1423816.BACQ01000027_gene974 6.7e-212 743.0 Lactobacillaceae Bacteria 1TPE1@1239,3F3NJ@33958,4HA65@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family FFAGCILK_02935 543734.LCABL_27950 2e-68 265.0 Lactobacillaceae gshR 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 Bacteria 1TS0Z@1239,3F3K2@33958,4HBYB@91061,COG1249@1,COG1249@2 NA|NA|NA C Glutathione reductase FFAGCILK_02937 1423775.BAMN01000043_gene24 1.6e-118 432.6 Lactobacillaceae Bacteria 1V8VU@1239,3F45C@33958,4HWIQ@91061,COG5527@1,COG5527@2 NA|NA|NA L Initiator Replication protein FFAGCILK_02939 1116231.SMA_p0014 1.2e-15 89.4 Bacilli mobC Bacteria 1VF06@1239,2E4NU@1,32ZHN@2,4HPMK@91061 NA|NA|NA S Bacterial mobilisation protein (MobC) FFAGCILK_02940 1116231.SMA_p0015 3.1e-101 375.6 Bacilli ko:K02557,ko:K18376 ko02030,ko02040,map02030,map02040 M00660 ko00000,ko00001,ko00002,ko02000,ko02035,ko02044 1.A.30.1,1.C.65.1 Bacteria 1UI9G@1239,4ISNN@91061,COG1196@1,COG1196@2 NA|NA|NA D Relaxase/Mobilisation nuclease domain FFAGCILK_02941 1302286.BAOT01000076_gene2219 3.2e-113 414.5 Lactobacillaceae Bacteria 1U6EU@1239,2DKQ9@1,30AAV@2,3F7RH@33958,4IG6M@91061 NA|NA|NA FFAGCILK_02942 1229520.ADIAL_1901 4e-29 135.6 Carnobacteriaceae 3.6.4.12 ko:K03722 ko00000,ko01000,ko03400 Bacteria 1URXJ@1239,27HHM@186828,4HF1N@91061,COG1199@1,COG1199@2 NA|NA|NA KL HELICc2 FFAGCILK_02943 913848.AELK01000025_gene1955 2.6e-12 77.4 Lactobacillaceae Bacteria 1U721@1239,29PUH@1,30ASN@2,3F8VN@33958,4IGWH@91061 NA|NA|NA FFAGCILK_02944 1133569.AHYZ01000171_gene111 2.6e-45 188.0 Lactobacillaceae XK27_01125 ko:K07484 ko00000 Bacteria 1VAJD@1239,3F7E1@33958,4HKCG@91061,COG3436@1,COG3436@2 NA|NA|NA L PFAM IS66 Orf2 family protein # 2681 queries scanned # Total time (seconds): 5.73043298721 # Rate: 467.85 q/s