# emapper version: emapper-2.0.1b-2-g816e190 emapper DB: 2.0
# command: ./emapper.py  -i Streptococcus_thermophilus/1.contigAnn/FFN/A00000050.ffn --translate --temp_dir Streptococcus_thermophilus/4.eggNOG_mapper --output_dir Streptococcus_thermophilus/4.eggNOG_mapper --output A00000050 --cpu 36 --keep_mapping_files -m diamond
# time: Wed Jul 13 07:39:23 2022
#query_name	seed_eggNOG_ortholog	seed_ortholog_evalue	seed_ortholog_score	best_tax_level	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	taxonomic scope	eggNOG OGs	best eggNOG OG	COG Functional cat.	eggNOG free text desc.
AHPHCOMF_00001	999425.HMPREF9186_00913	2.8e-115	421.4	Bacilli													Bacteria	1TRQB@1239,4HAY3@91061,COG1028@1,COG1028@2	NA|NA|NA	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family
AHPHCOMF_00002	888746.HMPREF9180_1259	1.6e-10	71.6	Bacilli													Bacteria	1W4NX@1239,2DD3F@1,2ZGBB@2,4I0KR@91061	NA|NA|NA		
AHPHCOMF_00003	322159.STER_0946	9e-98	362.8	Bacilli													Bacteria	1TSUJ@1239,4IPZN@91061,COG1309@1,COG1309@2	NA|NA|NA	K	Transcriptional regulator, TetR family
AHPHCOMF_00004	322159.STER_0947	1.8e-159	568.5	Bacilli	czcD			ko:K16264					ko00000,ko02000	2.A.4.1			Bacteria	1TR92@1239,4HBCQ@91061,COG1230@1,COG1230@2	NA|NA|NA	P	cation diffusion facilitator family transporter
AHPHCOMF_00005	322159.STER_0948	2.7e-210	737.6	Bacilli	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPKF@1239,4HAYG@91061,COG0276@1,COG0276@2	NA|NA|NA	H	Catalyzes the ferrous insertion into protoporphyrin IX
AHPHCOMF_00006	322159.STER_0949	6.2e-196	689.9	Bacilli	adhB		1.1.1.1,1.1.1.14	ko:K00001,ko:K00008	ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	M00014	R00623,R00754,R00875,R01896,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00085,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPIW@1239,4HB2G@91061,COG1063@1,COG1063@2	NA|NA|NA	E	Dehydrogenase
AHPHCOMF_00007	1046629.Ssal_01058	6e-08	62.0	Bacilli				ko:K06889					ko00000				Bacteria	1TPW7@1239,4HEFQ@91061,COG1073@1,COG1073@2	NA|NA|NA	S	Hydrolases of the alpha beta superfamily
AHPHCOMF_00008	264199.stu0937	7.9e-17	92.0	Bacteria													Bacteria	COG4814@1,COG4814@2	NA|NA|NA	S	Alpha/beta hydrolase of unknown function (DUF915)
AHPHCOMF_00009	264199.stu0938	4.5e-79	300.4	Bacteria													Bacteria	COG4814@1,COG4814@2	NA|NA|NA	S	Alpha/beta hydrolase of unknown function (DUF915)
AHPHCOMF_00012	264199.stu0941	2.6e-143	514.6	Bacilli			2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100		R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000				Bacteria	1TQ71@1239,4HUI7@91061,COG2820@1,COG2820@2	NA|NA|NA	F	Phosphorylase superfamily
AHPHCOMF_00013	322159.STER_0956	4.1e-118	430.6	Bacilli	gph		3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130		R01334	RC00017	ko00000,ko00001,ko01000				Bacteria	1TPPZ@1239,4IPIP@91061,COG0546@1,COG0546@2	NA|NA|NA	S	HAD hydrolase, family IA, variant 1
AHPHCOMF_00014	1046629.Ssal_01070	9.4e-15	85.1	Bacilli	yclQ			ko:K02016	ko02010,map02010	M00240			ko00000,ko00001,ko00002,ko02000	3.A.1.14			Bacteria	1UXCZ@1239,4HAMP@91061,COG4607@1,COG4607@2	NA|NA|NA	P	ABC-type enterochelin transport system, periplasmic component
AHPHCOMF_00015	1046629.Ssal_01070	3.3e-19	100.9	Bacilli	yclQ			ko:K02016	ko02010,map02010	M00240			ko00000,ko00001,ko00002,ko02000	3.A.1.14			Bacteria	1UXCZ@1239,4HAMP@91061,COG4607@1,COG4607@2	NA|NA|NA	P	ABC-type enterochelin transport system, periplasmic component
AHPHCOMF_00016	904306.HMPREF9192_1770	3.9e-15	86.7	Bacilli	dinF												Bacteria	1TNZN@1239,4HANM@91061,COG0534@1,COG0534@2	NA|NA|NA	V	Mate efflux family protein
AHPHCOMF_00018	264199.stu0950	2.1e-310	1070.8	Bacilli	FbpA			ko:K12341	ko03070,map03070				ko00000,ko00001,ko02044	1.B.40.1.1			Bacteria	1TQ8A@1239,4H9UF@91061,COG1293@1,COG1293@2	NA|NA|NA	K	RNA-binding protein homologous to eukaryotic snRNP
AHPHCOMF_00019	322159.STER_0961	3.7e-190	670.6	Bacilli													Bacteria	1VZGH@1239,2FKAH@1,34BY1@2,4I10M@91061	NA|NA|NA		
AHPHCOMF_00020	322159.STER_0962	3.1e-89	334.3	Bacilli	FNV0100												Bacteria	1V4ND@1239,4HJ5H@91061,COG1051@1,COG1051@2	NA|NA|NA	F	Belongs to the Nudix hydrolase family
AHPHCOMF_00021	322159.STER_0963	3.5e-28	130.2	Bacteria			3.4.13.21	ko:K05995,ko:K06888					ko00000,ko01000,ko01002				Bacteria	COG4405@1,COG4405@2	NA|NA|NA	I	Protein conserved in bacteria
AHPHCOMF_00023	322159.STER_0965	3.7e-117	427.6	Bacilli													Bacteria	1V7WE@1239,2B4EH@1,31X62@2,4HM57@91061	NA|NA|NA	S	TraX protein
AHPHCOMF_00024	264199.stu0953	5.9e-97	360.1	Bacilli	thiJ		2.7.11.1,3.5.1.124	ko:K03152,ko:K05520,ko:K12132					ko00000,ko01000,ko01001,ko01002				Bacteria	1V3WB@1239,4HM36@91061,COG0693@1,COG0693@2	NA|NA|NA	S	DJ-1 family
AHPHCOMF_00025	264199.stu0954	1.3e-148	532.3	Bacilli	pyrK	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042602,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0052875,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576		ko:K02823	ko00240,ko01100,map00240,map01100				ko00000,ko00001			iYO844.BSU15530	Bacteria	1TQ5D@1239,4HAU4@91061,COG0543@1,COG0543@2	NA|NA|NA	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
AHPHCOMF_00026	264199.stu0955	3.2e-175	620.9	Bacilli	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.98.1	ko:K00226,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01867,R01869	RC00051	ko00000,ko00001,ko00002,ko01000			iYO844.BSU15540	Bacteria	1TPFV@1239,4HA5H@91061,COG0167@1,COG0167@2	NA|NA|NA	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
AHPHCOMF_00027	322159.STER_0970	1.2e-180	639.0	Firmicutes	cas1	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944		ko:K15342					ko00000,ko02048,ko03400				Bacteria	1TQWG@1239,COG1518@1,COG1518@2	NA|NA|NA	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AHPHCOMF_00028	264199.stu0958	3.7e-54	217.2	Firmicutes	cas2			ko:K09951					ko00000,ko02048				Bacteria	1VFRC@1239,COG1343@1,COG1343@2	NA|NA|NA	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AHPHCOMF_00029	264199.stu0959	6.8e-133	479.9	Bacilli	cas6			ko:K19091					ko00000,ko01000,ko02048				Bacteria	1V7VJ@1239,4HZ1B@91061,COG5551@1,COG5551@2	NA|NA|NA	S	Pfam:DUF2276
AHPHCOMF_00030	264199.stu0960	0.0	1495.3	Bacilli	csm1	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K07016					ko00000,ko02048				Bacteria	1TRW5@1239,4HM8F@91061,COG1353@1,COG1353@2	NA|NA|NA	S	CRISPR-associated protein Csm1 family
AHPHCOMF_00031	264199.stu0961	5.6e-62	243.4	Bacilli	csm2			ko:K19138					ko00000,ko02048				Bacteria	1VGBY@1239,4HYAX@91061,COG1421@1,COG1421@2	NA|NA|NA	L	Pfam:DUF310
AHPHCOMF_00032	322159.STER_0975	1.1e-116	426.0	Bacilli	csm3			ko:K09002					ko00000,ko02048				Bacteria	1V3DM@1239,4HPB8@91061,COG1337@1,COG1337@2	NA|NA|NA	L	RAMP superfamily
AHPHCOMF_00033	264199.stu0963	5.8e-166	590.1	Firmicutes	csm4			ko:K19139					ko00000,ko02048				Bacteria	1V4UZ@1239,COG1567@1,COG1567@2	NA|NA|NA	L	CRISPR-associated RAMP protein, Csm4 family
AHPHCOMF_00034	322159.STER_0977	2.2e-204	718.0	Firmicutes	csm5	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944		ko:K19140					ko00000,ko02048				Bacteria	1V8JA@1239,COG1332@1,COG1332@2	NA|NA|NA	L	CRISPR-associated RAMP protein, Csm5 family
AHPHCOMF_00035	889204.HMPREF9423_0555	2.1e-14	84.0	Firmicutes	csm6												Bacteria	1TRJ6@1239,28K2E@1,2Z9RR@2	NA|NA|NA	S	Psort location Cytoplasmic, score
AHPHCOMF_00036	889204.HMPREF9423_0556	5.2e-74	285.0	Firmicutes	csm6												Bacteria	1TRJ6@1239,28K2E@1,2Z9RR@2	NA|NA|NA	S	Psort location Cytoplasmic, score
AHPHCOMF_00037	264199.stu0967	7e-127	459.9	Bacilli	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000			iECO103_1326.ECO103_1444,iECSF_1327.ECSF_1264,iSFV_1184.SFV_1294,iSF_1195.SF1285,iSFxv_1172.SFxv_1457,iS_1188.S1368,ic_1306.c1750	Bacteria	1TPPH@1239,4HAJ2@91061,COG0284@1,COG0284@2	NA|NA|NA	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
AHPHCOMF_00038	322159.STER_0981	7.5e-112	409.8	Bacilli	pyrE		2.4.2.10,4.1.1.23	ko:K00762,ko:K01591,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000			iYO844.BSU15560	Bacteria	1V1BZ@1239,4HFV7@91061,COG0461@1,COG0461@2	NA|NA|NA	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AHPHCOMF_00039	435842.HMPREF0848_00691	1.2e-63	249.2	Bacilli	nylA		3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120		R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000				Bacteria	1TPGJ@1239,4HBE7@91061,COG0154@1,COG0154@2	NA|NA|NA	J	Belongs to the amidase family
AHPHCOMF_00041	264199.stu0970	1.1e-267	928.7	Bacilli	dtpT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K03305					ko00000	2.A.17			Bacteria	1TP81@1239,4HAF2@91061,COG3104@1,COG3104@2	NA|NA|NA	E	transporter
AHPHCOMF_00042	264199.stu0973	8.5e-103	379.8	Bacilli	nylA		3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120		R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000				Bacteria	1TPGJ@1239,4HBE7@91061,COG0154@1,COG0154@2	NA|NA|NA	J	Belongs to the amidase family
AHPHCOMF_00043	435842.HMPREF0848_00690	8.8e-134	483.0	Bacilli	yckB			ko:K02030,ko:K02424	ko02010,map02010	M00234,M00236			ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3,3.A.1.3.10,3.A.1.3.14			Bacteria	1UHHG@1239,4H9NX@91061,COG0834@1,COG0834@2	NA|NA|NA	ET	Belongs to the bacterial solute-binding protein 3 family
AHPHCOMF_00044	699248.SRA_05851	1.8e-67	262.3	Bacilli	yecS	GO:0000099,GO:0000101,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006791,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015184,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015811,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:0098656,GO:1901682,GO:1902475,GO:1903825,GO:1905039		ko:K10009	ko02010,map02010	M00234			ko00000,ko00001,ko00002,ko02000	3.A.1.3.10,3.A.1.3.14		iJN746.PP_0226	Bacteria	1TQ43@1239,4HCZV@91061,COG0765@1,COG0765@2	NA|NA|NA	P	ABC transporter (Permease
AHPHCOMF_00046	264199.stu0979	8.1e-114	416.4	Bacilli	sasH		3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110		R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000				Bacteria	1TPV2@1239,4H9VJ@91061,COG0737@1,COG0737@2	NA|NA|NA	F	Belongs to the 5'-nucleotidase family
AHPHCOMF_00047	904306.HMPREF9192_1759	9.8e-35	152.5	Bacteria			3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240		R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000				Bacteria	COG0737@1,COG0737@2	NA|NA|NA	F	nucleotide catabolic process
AHPHCOMF_00048	264199.stu0981	1.4e-104	385.6	Bacteria	yfiF3												Bacteria	COG4977@1,COG4977@2	NA|NA|NA	K	sequence-specific DNA binding
AHPHCOMF_00049	322159.STER_0992	1.6e-247	861.7	Bacilli	mnmE	GO:0003674,GO:0005488,GO:0005515,GO:0042802		ko:K03650			R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016				Bacteria	1TPJF@1239,4HA06@91061,COG0486@1,COG0486@2	NA|NA|NA	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AHPHCOMF_00050	322159.STER_0993	1.8e-240	838.2	Bacilli	agcS	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K03310					ko00000	2.A.25			Bacteria	1TNZP@1239,4H9SZ@91061,COG1115@1,COG1115@2	NA|NA|NA	E	(Alanine) symporter
AHPHCOMF_00051	322159.STER_0994	0.0	1399.8	Bacilli	pcrA		3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430				ko00000,ko00001,ko01000,ko03400				Bacteria	1TPSU@1239,4HB12@91061,COG0210@1,COG0210@2	NA|NA|NA	L	ATP-dependent DNA helicase
AHPHCOMF_00052	322159.STER_0995	4.6e-241	840.1	Bacilli	metY		2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100		R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000				Bacteria	1VYCY@1239,4H9X5@91061,COG2873@1,COG2873@2	NA|NA|NA	E	o-acetylhomoserine
AHPHCOMF_00053	264199.stu0988	1.8e-59	235.0	Bacteria													Bacteria	COG0561@1,COG0561@2	NA|NA|NA	Q	phosphatase activity
AHPHCOMF_00054	904306.HMPREF9192_1752	9.3e-62	242.7	Bacilli													Bacteria	1TQTU@1239,4HEHK@91061,COG0561@1,COG0561@2	NA|NA|NA	S	haloacid dehalogenase-like hydrolase
AHPHCOMF_00055	264199.stu0990	3.5e-88	330.9	Bacilli	tpx	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009405,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0020012,GO:0030312,GO:0030682,GO:0032843,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K11065					ko00000,ko01000				Bacteria	1V474@1239,4HFMW@91061,COG2077@1,COG2077@2	NA|NA|NA	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AHPHCOMF_00056	264199.stu0991	1.1e-110	406.0	Bacilli	hsdS2		2.1.1.72	ko:K03427					ko00000,ko01000,ko02048				Bacteria	1VQES@1239,4HE4K@91061,COG0732@1,COG0732@2	NA|NA|NA	V	Type I restriction modification DNA specificity domain
AHPHCOMF_00057	264199.stu0993	1.7e-96	358.6	Bacilli	XK27_04775			ko:K09155					ko00000				Bacteria	1TRD5@1239,4HAAW@91061,COG2461@1,COG2461@2	NA|NA|NA	S	hemerythrin HHE cation binding domain
AHPHCOMF_00058	435842.HMPREF0848_00680	2.6e-49	201.1	Bacilli	XK27_04775			ko:K09155					ko00000				Bacteria	1TRD5@1239,4HAAW@91061,COG2461@1,COG2461@2	NA|NA|NA	S	hemerythrin HHE cation binding domain
AHPHCOMF_00059	322159.STER_1000	4.9e-151	540.4	Bacilli	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177,ko:K03483					ko00000,ko01000,ko03000,ko03016			iSB619.SA_RS06305	Bacteria	1TP9Y@1239,4HA9X@91061,COG0130@1,COG0130@2	NA|NA|NA	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AHPHCOMF_00060	322159.STER_1001	5.3e-175	620.2	Bacilli	ribF		2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000			iSB619.SA_RS06310	Bacteria	1TPKS@1239,4H9KE@91061,COG0196@1,COG0196@2	NA|NA|NA	H	Belongs to the ribF family
AHPHCOMF_00061	264199.stu0997	1.4e-71	275.4	Bacilli	spxA		1.20.4.1	ko:K00537,ko:K16509					ko00000,ko01000				Bacteria	1V3QC@1239,4HH0I@91061,COG1393@1,COG1393@2	NA|NA|NA	K	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
AHPHCOMF_00062	264199.stu0998	1.9e-43	181.4	Bacilli	yktA			ko:K16509					ko00000				Bacteria	1VEK8@1239,4HNKR@91061,COG4476@1,COG4476@2	NA|NA|NA	S	Belongs to the UPF0223 family
AHPHCOMF_00063	322159.STER_1004	5e-142	510.4	Bacilli	suhB		3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000				Bacteria	1TR4E@1239,4HB92@91061,COG0483@1,COG0483@2	NA|NA|NA	G	Belongs to the inositol monophosphatase superfamily
AHPHCOMF_00064	322159.STER_1005	3e-256	890.6	Bacilli	rsmF	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176,2.1.1.178	ko:K03500,ko:K11392					ko00000,ko01000,ko03009				Bacteria	1TPGQ@1239,4HCHQ@91061,COG0144@1,COG0144@2,COG3270@1,COG3270@2	NA|NA|NA	J	NOL1 NOP2 sun family protein
AHPHCOMF_00065	322159.STER_1006	3.3e-158	564.3	Bacilli	pstS	GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234		ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222			ko00000,ko00001,ko00002,ko02000	3.A.1.7			Bacteria	1TQ5X@1239,4HBEB@91061,COG0226@1,COG0226@2	NA|NA|NA	P	phosphate
AHPHCOMF_00066	264199.stu1002	2.5e-156	558.1	Bacilli	pstC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K02037	ko02010,map02010	M00222			ko00000,ko00001,ko00002,ko02000	3.A.1.7			Bacteria	1TSPP@1239,4HC9H@91061,COG0573@1,COG0573@2	NA|NA|NA	P	probably responsible for the translocation of the substrate across the membrane
AHPHCOMF_00067	322159.STER_1008	1.2e-155	555.8	Bacilli	pstA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K02038	ko02010,map02010	M00222			ko00000,ko00001,ko00002,ko02000	3.A.1.7			Bacteria	1TP74@1239,4HAKF@91061,COG0581@1,COG0581@2	NA|NA|NA	P	phosphate transport system permease
AHPHCOMF_00068	264199.stu1004	5.2e-150	537.0	Bacilli	pstB		3.6.3.27	ko:K02036	ko02010,map02010	M00222			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7		iLJ478.TM1261	Bacteria	1TP1M@1239,4HAB1@91061,COG1117@1,COG1117@2	NA|NA|NA	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AHPHCOMF_00069	264199.stu1005	1.7e-139	501.9	Bacilli	pstB		3.6.3.27	ko:K02036	ko02010,map02010	M00222			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7		iLJ478.TM1261	Bacteria	1TP1M@1239,4HAB1@91061,COG1117@1,COG1117@2	NA|NA|NA	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AHPHCOMF_00070	264199.stu1006	2.4e-113	414.8	Bacilli	phoU			ko:K02039					ko00000				Bacteria	1URN3@1239,4HEU9@91061,COG0704@1,COG0704@2	NA|NA|NA	P	Plays a role in the regulation of phosphate uptake
AHPHCOMF_00071	264199.stu1007	0.0	1687.9	Bacilli	pepN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100		R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002				Bacteria	1TR43@1239,4HA20@91061,COG0308@1,COG0308@2	NA|NA|NA	E	aminopeptidase
AHPHCOMF_00072	322159.STER_1013	7e-195	686.4	Bacilli	xerS	GO:0000150,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360											Bacteria	1URNQ@1239,4HEPI@91061,COG4974@1,COG4974@2	NA|NA|NA	D	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
AHPHCOMF_00073	264199.stu1009	1.5e-186	658.7	Bacilli	lplA		6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100		R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000				Bacteria	1TQ5U@1239,4H9P6@91061,COG0095@1,COG0095@2	NA|NA|NA	H	Lipoate-protein ligase
AHPHCOMF_00076	264199.stu1012	0.0	1496.5	Bacilli	glgP		2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931		R02111		ko00000,ko00001,ko01000		GT35		Bacteria	1TQAJ@1239,4H9XI@91061,COG0058@1,COG0058@2	NA|NA|NA	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
AHPHCOMF_00077	264199.stu1013	1.2e-304	1051.6	Bacilli	malQ		2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100		R05196	RC00049	ko00000,ko00001,ko01000		GH77		Bacteria	1W5VQ@1239,4HCHB@91061,COG1640@1,COG1640@2	NA|NA|NA	G	4-alpha-glucanotransferase
AHPHCOMF_00078	1069533.Sinf_0020	2.3e-23	114.4	Firmicutes													Bacteria	1TQ93@1239,COG3464@1,COG3464@2	NA|NA|NA	L	Transposase
AHPHCOMF_00079	264199.stu1020	4.6e-25	119.8	Bacteria	tatA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944		ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336			ko00000,ko00001,ko00002,ko02044	2.A.64			Bacteria	COG1826@1,COG1826@2	NA|NA|NA	U	protein secretion
AHPHCOMF_00080	264199.stu1021	2e-121	441.8	Bacilli	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680		ko:K03118	ko03060,ko03070,map03060,map03070	M00336			ko00000,ko00001,ko00002,ko02044	2.A.64			Bacteria	1U7N7@1239,4HB1U@91061,COG0805@1,COG0805@2	NA|NA|NA	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AHPHCOMF_00081	322159.STER_1022	3.5e-297	1026.9	Bacilli	ywbL			ko:K07243					ko00000,ko02000	2.A.108.1,2.A.108.2			Bacteria	1TQIA@1239,4HCJZ@91061,COG0672@1,COG0672@2	NA|NA|NA	P	COG0672 High-affinity Fe2 Pb2 permease
AHPHCOMF_00082	322159.STER_1023	1.6e-232	811.6	Bacilli	ycdB			ko:K16301					ko00000,ko01000,ko02000	2.A.108.2.3			Bacteria	1UY9Y@1239,4HACQ@91061,COG2837@1,COG2837@2	NA|NA|NA	P	peroxidase
AHPHCOMF_00083	322159.STER_1024	3.2e-153	547.7	Bacilli	ycdO	GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0008150,GO:0015684,GO:0030001,GO:0051179,GO:0051234,GO:0070838,GO:0072511		ko:K07224,ko:K07243					ko00000,ko02000	2.A.108.1,2.A.108.2,2.A.108.2.3			Bacteria	1TS89@1239,4HB0W@91061,COG2822@1,COG2822@2	NA|NA|NA	P	periplasmic lipoprotein involved in iron transport
AHPHCOMF_00084	322159.STER_1025	2e-178	631.7	Bacilli	fatB			ko:K02016	ko02010,map02010	M00240			ko00000,ko00001,ko00002,ko02000	3.A.1.14			Bacteria	1UXCZ@1239,4HAMP@91061,COG4607@1,COG4607@2	NA|NA|NA	P	ABC-type enterochelin transport system, periplasmic component
AHPHCOMF_00085	264199.stu1026	6.8e-136	490.0	Bacilli	yclP		3.6.3.34	ko:K02013	ko02010,map02010	M00240			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14			Bacteria	1UHP5@1239,4HBJE@91061,COG4604@1,COG4604@2	NA|NA|NA	P	abc transporter atp-binding protein
AHPHCOMF_00086	322159.STER_1027	5.6e-167	593.6	Bacilli	fatC			ko:K02015	ko02010,map02010	M00240			ko00000,ko00001,ko00002,ko02000	3.A.1.14			Bacteria	1TP3V@1239,4HAHE@91061,COG4605@1,COG4605@2	NA|NA|NA	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AHPHCOMF_00087	322159.STER_1028	1e-165	589.3	Bacilli	yclN			ko:K02015	ko02010,map02010	M00240			ko00000,ko00001,ko00002,ko02000	3.A.1.14			Bacteria	1TSQX@1239,4H9P2@91061,COG4606@1,COG4606@2	NA|NA|NA	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AHPHCOMF_00088	1046629.Ssal_01131	1.5e-33	148.7	Bacilli	pulA		3.2.1.1,3.2.1.41	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973		R02108,R02111,R02112,R11262		ko00000,ko00001,ko01000		CBM48,GH13		Bacteria	1TP3M@1239,4HBP5@91061,COG1523@1,COG1523@2	NA|NA|NA	G	belongs to the glycosyl hydrolase 13 family
AHPHCOMF_00089	264199.stu1031	3.7e-85	320.9	Bacilli	pulA		3.2.1.1,3.2.1.41	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973		R02108,R02111,R02112,R11262		ko00000,ko00001,ko01000		CBM48,GH13		Bacteria	1TP3M@1239,4HBP5@91061,COG1523@1,COG1523@2	NA|NA|NA	G	belongs to the glycosyl hydrolase 13 family
AHPHCOMF_00090	1046629.Ssal_01131	1.7e-60	238.4	Bacilli	pulA		3.2.1.1,3.2.1.41	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973		R02108,R02111,R02112,R11262		ko00000,ko00001,ko01000		CBM48,GH13		Bacteria	1TP3M@1239,4HBP5@91061,COG1523@1,COG1523@2	NA|NA|NA	G	belongs to the glycosyl hydrolase 13 family
AHPHCOMF_00091	264199.stu1033	6.1e-66	256.9	Bacilli	pulA		3.2.1.1,3.2.1.41	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973		R02108,R02111,R02112,R11262		ko00000,ko00001,ko01000		CBM48,GH13		Bacteria	1TP3M@1239,4HBP5@91061,COG1523@1,COG1523@2	NA|NA|NA	G	belongs to the glycosyl hydrolase 13 family
AHPHCOMF_00092	1046629.Ssal_01131	4.4e-133	480.7	Bacilli	pulA		3.2.1.1,3.2.1.41	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973		R02108,R02111,R02112,R11262		ko00000,ko00001,ko01000		CBM48,GH13		Bacteria	1TP3M@1239,4HBP5@91061,COG1523@1,COG1523@2	NA|NA|NA	G	belongs to the glycosyl hydrolase 13 family
AHPHCOMF_00093	435842.HMPREF0848_00645	1.9e-37	161.4	Bacteria			3.5.1.28	ko:K01448,ko:K02395,ko:K21471	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036				Bacteria	COG0860@1,COG0860@2,COG1705@1,COG1705@2,COG3757@1,COG3757@2,COG5263@1,COG5263@2	NA|NA|NA	NU	amidase activity
AHPHCOMF_00094	904306.HMPREF9192_1715	8.5e-266	922.5	Bacteria			3.5.1.28	ko:K01448,ko:K02395,ko:K21471	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036				Bacteria	COG0860@1,COG0860@2,COG1705@1,COG1705@2,COG3757@1,COG3757@2,COG5263@1,COG5263@2	NA|NA|NA	NU	amidase activity
AHPHCOMF_00095	1046629.Ssal_01134	1.6e-83	316.2	Bacilli			3.4.17.14,3.5.1.28	ko:K01448,ko:K02395,ko:K07260,ko:K07273	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	M00651,M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036				Bacteria	1W25V@1239,4HGXW@91061,COG0860@1,COG0860@2,COG1705@1,COG1705@2,COG3757@1,COG3757@2	NA|NA|NA	M	GBS Bsp-like repeat
AHPHCOMF_00096	322159.STER_1033	0.0	1109.0	Bacilli	lpdA		1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1TP1W@1239,4H9Z5@91061,COG1249@1,COG1249@2	NA|NA|NA	C	Dehydrogenase
AHPHCOMF_00097	264199.stu1049	1.8e-198	698.7	Bacilli	acoC		2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	1TR5N@1239,4HDFT@91061,COG0508@1,COG0508@2	NA|NA|NA	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
AHPHCOMF_00098	264199.stu1050	3.7e-182	644.0	Bacilli	acoB		1.2.4.1,1.2.4.4	ko:K00162,ko:K11381,ko:K21417	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	1TP3J@1239,4HAP6@91061,COG0022@1,COG0022@2	NA|NA|NA	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
AHPHCOMF_00099	322159.STER_1036	6e-185	653.3	Bacilli	acoA		1.2.4.1,1.2.4.4	ko:K00161,ko:K11381,ko:K21416	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	1TQDG@1239,4HBEA@91061,COG1071@1,COG1071@2	NA|NA|NA	C	Dehydrogenase E1 component
AHPHCOMF_00100	264199.stu1052	5e-38	163.7	Bacteria													Bacteria	COG4907@1,COG4907@2	NA|NA|NA	P	membrane protein (DUF2207)
AHPHCOMF_00101	904306.HMPREF9192_1709	1.8e-64	251.9	Bacilli													Bacteria	1TS3Q@1239,4HF7D@91061,COG4907@1,COG4907@2	NA|NA|NA	S	the current gene model (or a revised gene model) may contain a frame shift
AHPHCOMF_00102	264199.stu1054	3.7e-235	820.5	Bacilli	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPQM@1239,4HA90@91061,COG0044@1,COG0044@2	NA|NA|NA	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
AHPHCOMF_00103	322159.STER_1041	2.9e-127	461.1	Firmicutes	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340				ko00000,ko00001,ko01000,ko03400				Bacteria	1TPSN@1239,COG0692@1,COG0692@2	NA|NA|NA	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AHPHCOMF_00104	264199.stu1056	8.6e-218	762.7	Bacilli	yeaB												Bacteria	1TSGY@1239,4H9WP@91061,COG0053@1,COG0053@2,COG4994@1,COG4994@2	NA|NA|NA	K	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AHPHCOMF_00105	264199.stu1058	2.9e-21	107.1	Bacteria	dacA1		3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100				ko00000,ko00001,ko01000,ko01002,ko01011				Bacteria	COG1686@1,COG1686@2	NA|NA|NA	M	Belongs to the peptidase S11 family
AHPHCOMF_00106	264199.stu1059	3.4e-22	110.2	Bacilli			3.4.16.4	ko:K01286					ko00000,ko01000				Bacteria	1TQN0@1239,4HD0P@91061,COG1686@1,COG1686@2	NA|NA|NA	M	Belongs to the peptidase S11 family
AHPHCOMF_00107	264199.stu1059	2.3e-26	124.4	Bacilli			3.4.16.4	ko:K01286					ko00000,ko01000				Bacteria	1TQN0@1239,4HD0P@91061,COG1686@1,COG1686@2	NA|NA|NA	M	Belongs to the peptidase S11 family
AHPHCOMF_00108	264199.stu1059	4.3e-83	313.9	Bacilli			3.4.16.4	ko:K01286					ko00000,ko01000				Bacteria	1TQN0@1239,4HD0P@91061,COG1686@1,COG1686@2	NA|NA|NA	M	Belongs to the peptidase S11 family
AHPHCOMF_00109	322159.STER_1044	1.2e-157	562.4	Bacilli	rssA												Bacteria	1TQ9W@1239,4HCHJ@91061,COG4667@1,COG4667@2	NA|NA|NA	S	Phospholipase, patatin family
AHPHCOMF_00110	322159.STER_1045	3.9e-78	297.4	Bacilli	estA												Bacteria	1V1B9@1239,4HGED@91061,COG2755@1,COG2755@2	NA|NA|NA	E	GDSL-like protein
AHPHCOMF_00111	904306.HMPREF9192_1701	2.6e-15	87.4	Bacilli	estA												Bacteria	1VHUN@1239,4IPN1@91061,COG2755@1,COG2755@2	NA|NA|NA	E	Lysophospholipase L1 and related esterases
AHPHCOMF_00112	264199.stu1062	5.3e-292	1009.6	Bacilli				ko:K03688					ko00000				Bacteria	1TPIV@1239,4HBW3@91061,COG0661@1,COG0661@2	NA|NA|NA	S	unusual protein kinase
AHPHCOMF_00113	322159.STER_1048	4.9e-39	166.8	Bacilli													Bacteria	1VK6K@1239,4HRS5@91061,COG3937@1,COG3937@2	NA|NA|NA	S	granule-associated protein
AHPHCOMF_00114	1046629.Ssal_01160	4.6e-138	497.3	Bacilli	bglH		3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500		R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000		GT1		Bacteria	1TP19@1239,4HA1W@91061,COG2723@1,COG2723@2	NA|NA|NA	G	Belongs to the glycosyl hydrolase 1 family
AHPHCOMF_00115	1123318.KB904593_gene1608	2e-18	97.4	Bacilli	bglH		3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500		R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000		GT1		Bacteria	1TP19@1239,4HA1W@91061,COG2723@1,COG2723@2	NA|NA|NA	G	Belongs to the glycosyl hydrolase 1 family
AHPHCOMF_00116	322159.STER_1050	1.3e-199	702.2	Bacilli													Bacteria	1TQBF@1239,4HGFS@91061,COG0628@1,COG0628@2	NA|NA|NA	S	hmm pf01594
AHPHCOMF_00117	1046629.Ssal_01162	1.1e-87	329.3	Bacilli													Bacteria	1UXY8@1239,4HFD9@91061,COG0406@1,COG0406@2	NA|NA|NA	G	Belongs to the phosphoglycerate mutase family
AHPHCOMF_00118	264199.stu1071	8.4e-69	266.2	Bacteria	supH		3.1.3.102,3.1.3.104	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00548,R07280	RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	COG0561@1,COG0561@2	NA|NA|NA	Q	phosphatase activity
AHPHCOMF_00119	1046629.Ssal_01165	9.2e-15	85.5	Bacilli	supH		3.1.3.102,3.1.3.104	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00548,R07280	RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	1V1SQ@1239,4IPTG@91061,COG0561@1,COG0561@2	NA|NA|NA	S	Sucrose-6F-phosphate phosphohydrolase
AHPHCOMF_00120	322159.STER_1054	5.8e-95	353.6	Bacilli													Bacteria	1VA6K@1239,4HKNU@91061,COG4767@1,COG4767@2	NA|NA|NA	V	VanZ like family
AHPHCOMF_00121	264199.stu1086	5.5e-178	630.2	Firmicutes													Bacteria	1TQ93@1239,COG3464@1,COG3464@2	NA|NA|NA	L	Transposase
AHPHCOMF_00122	1214166.ALLG01000021_gene12	5.6e-20	102.8	Streptococcus suis	rmlC		1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000				Bacteria	1TRVB@1239,1WSMH@1307,4HFQB@91061,COG1898@1,COG1898@2	NA|NA|NA	M	dTDP-4-dehydrorhamnose 3,5-epimerase
AHPHCOMF_00123	1123314.AUIO01000001_gene1551	2.7e-160	571.2	Bacilli	rfbA	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005996,GO:0006006,GO:0006139,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009117,GO:0009141,GO:0009147,GO:0009200,GO:0009211,GO:0009219,GO:0009225,GO:0009226,GO:0009262,GO:0009394,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019299,GO:0019300,GO:0019305,GO:0019318,GO:0019319,GO:0019438,GO:0019637,GO:0019692,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0045226,GO:0046075,GO:0046364,GO:0046379,GO:0046383,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000			iNJ661.Rv0334	Bacteria	1V301@1239,4H9R0@91061,COG1209@1,COG1209@2	NA|NA|NA	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AHPHCOMF_00124	1123314.AUIO01000001_gene1552	7.3e-248	862.8	Bacilli	cps1C												Bacteria	1TP7R@1239,4HC84@91061,COG2244@1,COG2244@2	NA|NA|NA	S	Polysaccharide biosynthesis protein
AHPHCOMF_00125	1123314.AUIO01000001_gene1553	1.2e-141	509.6	Bacilli	cps1B			ko:K20444					ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4		Bacteria	1UZZR@1239,4IQ10@91061,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyl transferases group 1
AHPHCOMF_00126	500632.CLONEX_02034	1.7e-36	160.6	Clostridia													Bacteria	1V87U@1239,24MTW@186801,2AH6X@1,317GS@2	NA|NA|NA	S	Psort location CytoplasmicMembrane, score 9.99
AHPHCOMF_00127	1123314.AUIO01000001_gene1554	2.9e-80	305.4	Bacteria	sacB			ko:K20444					ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4		Bacteria	COG0438@1,COG0438@2	NA|NA|NA	M	transferase activity, transferring glycosyl groups
AHPHCOMF_00128	888746.HMPREF9180_1597	4.9e-68	264.2	Bacilli	sacB			ko:K20444					ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4		Bacteria	1TPG9@1239,4HGEP@91061,COG0438@1,COG0438@2	NA|NA|NA	M	Stealth protein CR2, conserved region 2
AHPHCOMF_00129	862970.SAIN_1722	1.1e-149	536.2	Bacilli													Bacteria	1V0TF@1239,4ISVG@91061,COG1215@1,COG1215@2	NA|NA|NA	M	Glycosyltransferase, group 2 family protein
AHPHCOMF_00130	904306.HMPREF9192_1681	8.5e-87	326.2	Bacilli	Z012_10770												Bacteria	1V8R9@1239,4HW77@91061,COG3955@1,COG3955@2	NA|NA|NA	M	Domain of unknown function (DUF1919)
AHPHCOMF_00131	1116231.SMA_0863	1.1e-209	735.7	Bacilli	wcoF												Bacteria	1TR6R@1239,4HEIZ@91061,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyltransferase, group 1 family protein
AHPHCOMF_00132	904306.HMPREF9192_1679	4.5e-219	766.9	Bacilli	rgpAc			ko:K12996					ko00000,ko01000,ko01003,ko01005		GT4		Bacteria	1TR0Y@1239,4IPU2@91061,COG0438@1,COG0438@2	NA|NA|NA	M	group 1 family protein
AHPHCOMF_00133	264199.stu1108	2.7e-255	887.5	Bacilli	cpsE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944											Bacteria	1TP7M@1239,4HB3Z@91061,COG2148@1,COG2148@2	NA|NA|NA	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
AHPHCOMF_00134	322159.STER_1068	1.1e-117	429.5	Bacilli	cpsD												Bacteria	1TS4R@1239,4HCEN@91061,COG0489@1,COG0489@2	NA|NA|NA	D	COG0489 ATPases involved in chromosome partitioning
AHPHCOMF_00135	1046629.Ssal_01180	4.7e-107	394.0	Bacilli	cps4C												Bacteria	1UZCR@1239,4HE26@91061,COG3944@1,COG3944@2	NA|NA|NA	M	biosynthesis protein
AHPHCOMF_00136	264199.stu1111	1.1e-135	489.2	Bacilli	cpsB		3.1.3.48	ko:K01104					ko00000,ko01000				Bacteria	1TQ1T@1239,4HDZR@91061,COG4464@1,COG4464@2	NA|NA|NA	GM	Capsular polysaccharide biosynthesis protein
AHPHCOMF_00137	322159.STER_1071	1.5e-251	875.2	Bacilli	cps4A												Bacteria	1TR1B@1239,4HDRS@91061,COG1316@1,COG1316@2	NA|NA|NA	K	Cell envelope-like function transcriptional attenuator common domain protein
AHPHCOMF_00138	322159.STER_1072	5.8e-129	466.8	Bacilli	deoD	GO:0003674,GO:0003824,GO:0004731,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006152,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009164,GO:0009987,GO:0015949,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0019686,GO:0033554,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658	2.4.2.1,2.4.2.28	ko:K00772,ko:K03784	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000			iAPECO1_1312.APECO1_1997,iB21_1397.B21_04226,iE2348C_1286.E2348C_4682,iEC042_1314.EC042_4881,iECABU_c1320.ECABU_c50190,iECBD_1354.ECBD_3636,iECB_1328.ECB_04260,iECD_1391.ECD_04260,iECED1_1282.ECED1_5255,iECIAI39_1322.ECIAI39_4916,iECNA114_1301.ECNA114_4626,iECO26_1355.ECO26_5590,iECOK1_1307.ECOK1_4950,iECP_1309.ECP_4768,iEcolC_1368.EcolC_3672,iLF82_1304.LF82_0467,iNRG857_1313.NRG857_22170,iPC815.YPO0440,iSFV_1184.SFV_4418,iSF_1195.SF4416,iSFxv_1172.SFxv_4809,iS_1188.S4687,iUMN146_1321.UM146_22680,iUMNK88_1353.UMNK88_5303,iUTI89_1310.UTI89_C5155,ic_1306.c5468	Bacteria	1TQPG@1239,4HADM@91061,COG0813@1,COG0813@2	NA|NA|NA	F	purine nucleoside phosphorylase
AHPHCOMF_00139	904306.HMPREF9192_1673	7e-38	162.9	Bacilli	yfeJ		6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002				Bacteria	1V97T@1239,4HIKV@91061,COG0518@1,COG0518@2	NA|NA|NA	F	glutamine amidotransferase
AHPHCOMF_00140	904306.HMPREF9192_1673	3.7e-67	260.8	Bacilli	yfeJ		6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002				Bacteria	1V97T@1239,4HIKV@91061,COG0518@1,COG0518@2	NA|NA|NA	F	glutamine amidotransferase
AHPHCOMF_00141	322159.STER_1075	4e-150	537.3	Bacilli	punA		2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110		R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000				Bacteria	1TQ37@1239,4HABP@91061,COG0005@1,COG0005@2	NA|NA|NA	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AHPHCOMF_00142	322159.STER_1077	9.3e-236	822.4	Bacilli	deoB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008973,GO:0016853,GO:0016866,GO:0016868,GO:0044424,GO:0044444,GO:0044464	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230		R01057,R02749	RC00408	ko00000,ko00001,ko01000				Bacteria	1TP70@1239,4H9RU@91061,COG1015@1,COG1015@2	NA|NA|NA	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AHPHCOMF_00143	264199.stu1121	1.7e-122	445.3	Bacilli	rpiA	GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	2.7.1.12,2.7.1.15,5.3.1.6	ko:K00851,ko:K00852,ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01051,R01056,R01737,R02750	RC00002,RC00017,RC00434	ko00000,ko00001,ko00002,ko01000				Bacteria	1V1DB@1239,4HFQ7@91061,COG0120@1,COG0120@2	NA|NA|NA	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AHPHCOMF_00145	435842.HMPREF0848_00593	6.1e-22	110.2	Bacilli													Bacteria	1VU2V@1239,4HU5W@91061,COG3266@1,COG3266@2	NA|NA|NA	V	Glucan-binding protein C
AHPHCOMF_00146	322159.STER_1082	1e-110	406.0	Bacilli	ung2		3.2.2.27	ko:K21929	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	1V1F8@1239,4HFVS@91061,COG1573@1,COG1573@2	NA|NA|NA	L	Uracil-DNA glycosylase
AHPHCOMF_00147	264199.stu1127	9e-275	952.2	Bacilli	pepV		3.5.1.18	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	M00016	R00899,R02734,R04951	RC00064,RC00090,RC00096,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002				Bacteria	1TPEG@1239,4HC14@91061,COG0624@1,COG0624@2	NA|NA|NA	E	Dipeptidase
AHPHCOMF_00148	264199.stu1128	6.4e-27	125.9	Bacilli	dmpI	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000				Bacteria	1VKD5@1239,4HRBS@91061,COG1942@1,COG1942@2	NA|NA|NA	G	Belongs to the 4-oxalocrotonate tautomerase family
AHPHCOMF_00149	264199.stu1129	2e-85	321.6	Bacilli	XK27_03610												Bacteria	1V77V@1239,4HKYX@91061,COG0454@1,COG0456@2	NA|NA|NA	K	Gnat family
AHPHCOMF_00150	1046629.Ssal_00123	9.1e-10	68.6	Bacilli				ko:K07491					ko00000				Bacteria	1V1CM@1239,4HBWU@91061,COG1943@1,COG1943@2	NA|NA|NA	L	COG1943 Transposase and inactivated derivatives
AHPHCOMF_00151	1046629.Ssal_01190	1.5e-56	225.3	Bacilli	rplT	GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141		ko:K02887	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V6DB@1239,4HH2W@91061,COG0292@1,COG0292@2	NA|NA|NA	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AHPHCOMF_00152	322159.STER_1088	2.1e-28	131.0	Bacilli	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904		ko:K02916	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1VF5W@1239,4HNIQ@91061,COG0291@1,COG0291@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL35 family
AHPHCOMF_00153	322159.STER_1089	3.5e-86	324.3	Bacilli	infC	GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767		ko:K02520					ko00000,ko03012,ko03029				Bacteria	1V1RC@1239,4HI4P@91061,COG0290@1,COG0290@2	NA|NA|NA	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AHPHCOMF_00154	322159.STER_1090	2.5e-121	441.4	Bacilli	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	1.17.7.4,2.5.1.19,2.7.1.26,2.7.4.25,2.7.7.2,6.3.2.1	ko:K00800,ko:K00945,ko:K02945,ko:K03527,ko:K03977,ko:K11753,ko:K13799	ko00240,ko00400,ko00410,ko00740,ko00770,ko00900,ko01100,ko01110,ko01130,ko01230,ko03010,map00240,map00400,map00410,map00740,map00770,map00900,map01100,map01110,map01130,map01230,map03010	M00022,M00052,M00096,M00119,M00125,M00178	R00158,R00161,R00512,R00549,R01665,R02473,R03460,R05884,R08210	RC00002,RC00017,RC00096,RC00141,RC00350,RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03009,ko03011			iPC815.YPO1391,iSDY_1059.SDY_2348	Bacteria	1V3IA@1239,4HFZE@91061,COG0283@1,COG0283@2	NA|NA|NA	F	Belongs to the cytidylate kinase family. Type 1 subfamily
AHPHCOMF_00155	264199.stu1136	2.8e-18	99.0	Bacilli													Bacteria	1VD79@1239,4HT02@91061,COG1388@1,COG1388@2	NA|NA|NA	M	LysM domain
AHPHCOMF_00156	264199.stu1138	2.9e-90	337.8	Bacilli	ebsA												Bacteria	1VQ5S@1239,2FI04@1,349T2@2,4HYC5@91061	NA|NA|NA	S	Family of unknown function (DUF5322)
AHPHCOMF_00157	322159.STER_1094	1.1e-228	798.9	Bacilli	pepT	GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0034701,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045148,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.4	ko:K01258					ko00000,ko01000,ko01002				Bacteria	1TP3A@1239,4HAZE@91061,COG2195@1,COG2195@2	NA|NA|NA	E	Cleaves the N-terminal amino acid of tripeptides
AHPHCOMF_00158	322159.STER_1096	1.8e-96	358.6	Bacilli	lepB		3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060				ko00000,ko00001,ko01000,ko01002				Bacteria	1V2BJ@1239,4HGCB@91061,COG0681@1,COG0681@2	NA|NA|NA	U	Belongs to the peptidase S26 family
AHPHCOMF_00159	264199.stu1141	2.4e-223	781.2	Bacilli													Bacteria	1TT97@1239,4HAIA@91061,COG0457@1,COG0457@2	NA|NA|NA	G	COG0457 FOG TPR repeat
AHPHCOMF_00160	264199.stu1142	6.2e-176	623.6	Bacilli	yubA												Bacteria	1TQ84@1239,4H9SR@91061,COG0628@1,COG0628@2	NA|NA|NA	S	permease
AHPHCOMF_00161	322159.STER_1099	4.6e-93	347.1	Bacilli	mutX		3.6.1.55	ko:K03574					ko00000,ko01000,ko03400				Bacteria	1V66I@1239,4HHRE@91061,COG1051@1,COG1051@2	NA|NA|NA	F	NTP pyrophosphohydrolases including oxidative damage repair enzymes
AHPHCOMF_00162	322159.STER_1100	3.6e-163	580.9	Bacilli	ftsX	GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0031224,GO:0031226,GO:0032506,GO:0034097,GO:0040007,GO:0042173,GO:0042221,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0090529,GO:1902531		ko:K09811,ko:K09812	ko02010,map02010	M00256			ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140			Bacteria	1TPND@1239,4HA5A@91061,COG2177@1,COG2177@2	NA|NA|NA	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
AHPHCOMF_00163	264199.stu1145	2.5e-124	451.4	Bacilli	ftsE	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363		ko:K09811,ko:K09812	ko02010,map02010	M00256			ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140			Bacteria	1TP58@1239,4H9Z2@91061,COG2884@1,COG2884@2	NA|NA|NA	D	cell division ATP-binding protein FtsE
AHPHCOMF_00164	264199.stu1146	1.6e-182	645.2	Bacilli	prfB	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576		ko:K02836					ko00000,ko03012				Bacteria	1TPSB@1239,4H9N2@91061,COG1186@1,COG1186@2	NA|NA|NA	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AHPHCOMF_00165	322159.STER_1104	1.2e-202	712.2	Bacilli	queG	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979					ko00000,ko01000,ko03016				Bacteria	1TP6Q@1239,4HAEW@91061,COG1600@1,COG1600@2	NA|NA|NA	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AHPHCOMF_00166	264199.stu1147	1.3e-181	642.1	Bacilli	yjjH												Bacteria	1V9B5@1239,4HJX0@91061,COG1409@1,COG1409@2	NA|NA|NA	S	Calcineurin-like phosphoesterase
AHPHCOMF_00167	322159.STER_1106	1.5e-135	488.8	Bacilli	nfrA		1.5.1.38,1.5.1.39	ko:K19285,ko:K19286	ko00740,ko01100,map00740,map01100		R05705,R05706	RC00126	ko00000,ko00001,ko01000				Bacteria	1UB8S@1239,4HEGP@91061,COG0778@1,COG0778@2	NA|NA|NA	C	nitroreductase
AHPHCOMF_00168	264199.stu1150	0.0	1622.4	Bacilli	pacL		3.6.3.8	ko:K01537					ko00000,ko01000	3.A.3.2			Bacteria	1TPF5@1239,4H9S5@91061,COG0474@1,COG0474@2	NA|NA|NA	P	cation transport ATPase
AHPHCOMF_00169	264199.stu1151	2.6e-67	261.2	Bacteria	ywiB												Bacteria	COG4506@1,COG4506@2	NA|NA|NA	S	Domain of unknown function (DUF1934)
AHPHCOMF_00170	322159.STER_1109	6.3e-51	206.5	Bacteria	XK27_00115		2.3.1.128	ko:K03789					ko00000,ko01000,ko03009				Bacteria	COG0454@1,COG0456@2	NA|NA|NA	K	acetyltransferase
AHPHCOMF_00171	264199.stu1154	9.2e-147	526.2	Bacilli	yidA	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050308											Bacteria	1TR16@1239,4HCZ6@91061,COG0561@1,COG0561@2	NA|NA|NA	S	hydrolases of the HAD superfamily
AHPHCOMF_00172	264199.stu1155	9e-231	805.8	Bacilli	murM		2.3.2.10,2.3.2.16	ko:K05363,ko:K11693,ko:K12554	ko00550,ko01100,map00550,map01100		R08776,R08779,R08780	RC00055,RC00064,RC00096	ko00000,ko00001,ko01000,ko01011				Bacteria	1TRZU@1239,4HC1Z@91061,COG2348@1,COG2348@2	NA|NA|NA	V	protein involved in methicillin resistance
AHPHCOMF_00173	322159.STER_1113	5e-35	153.3	Bacteria				ko:K09790					ko00000				Bacteria	COG2832@1,COG2832@2	NA|NA|NA	F	Protein of unknown function (DUF454)
AHPHCOMF_00174	322159.STER_1114	1e-153	549.3	Bacilli	vicX		3.1.26.11	ko:K00784	ko03013,map03013				ko00000,ko00001,ko01000,ko03016				Bacteria	1TQ8E@1239,4HAKD@91061,COG1235@1,COG1235@2	NA|NA|NA	S	Metal-dependent hydrolases of the beta-lactamase superfamily I
AHPHCOMF_00175	322159.STER_1115	1.4e-245	855.1	Bacilli	vicK		2.7.13.3	ko:K07652	ko02020,map02020	M00459			ko00000,ko00001,ko00002,ko01000,ko01001,ko02022				Bacteria	1TQ1H@1239,4HA52@91061,COG5002@1,COG5002@2	NA|NA|NA	T	Histidine kinase
AHPHCOMF_00176	322159.STER_1116	9.9e-129	466.1	Bacilli													Bacteria	1TPQG@1239,4HA8Q@91061,COG0745@1,COG0745@2	NA|NA|NA	KT	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AHPHCOMF_00177	264199.stu1161	3.3e-138	497.7	Bacilli	glnQ		3.6.3.21	ko:K02028,ko:K10041	ko02010,map02010	M00228,M00236			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3			Bacteria	1TNYD@1239,4H9WY@91061,COG1126@1,COG1126@2	NA|NA|NA	E	abc transporter atp-binding protein
AHPHCOMF_00178	322159.STER_1118	9.2e-150	536.2	Bacilli	peb1A	GO:0005575,GO:0005623,GO:0009986,GO:0044464		ko:K10039	ko02010,map02010	M00228			ko00000,ko00001,ko00002,ko02000	3.A.1.3			Bacteria	1TT11@1239,4HAHV@91061,COG0834@1,COG0834@2	NA|NA|NA	ET	ABC-type amino acid transport signal transduction systems, periplasmic component domain
AHPHCOMF_00179	322159.STER_1119	8e-115	419.9	Bacilli	gltJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K02029,ko:K10003,ko:K10040	ko02010,ko02020,map02010,map02020	M00228,M00230,M00236			ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.19,3.A.1.3.4		iJN746.PP_1070	Bacteria	1TQ5K@1239,4HE9C@91061,COG0765@1,COG0765@2	NA|NA|NA	P	ABC transporter (Permease
AHPHCOMF_00180	264199.stu1164	2.5e-110	404.8	Bacilli	tcyB_2			ko:K02029,ko:K02030,ko:K10040,ko:K17073,ko:K17074	ko02010,map02010	M00228,M00236,M00589			ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.20			Bacteria	1V14N@1239,4HJ9W@91061,COG0765@1,COG0765@2	NA|NA|NA	P	ABC transporter (permease)
AHPHCOMF_00181	264199.stu1165	3.5e-123	448.0	Bacilli	endA			ko:K15051					ko00000				Bacteria	1V4X2@1239,4HIF5@91061,COG2169@1,COG2169@2	NA|NA|NA	F	DNA RNA non-specific endonuclease
AHPHCOMF_00182	264199.stu1166	1.2e-25	121.7	Bacilli	epuA												Bacteria	1VMAH@1239,2EK0E@1,33DQZ@2,4HRG1@91061	NA|NA|NA	S	DNA-directed RNA polymerase subunit beta
AHPHCOMF_00183	322159.STER_1123	9.4e-231	805.8	Bacilli	murA		2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100		R00660	RC00350	ko00000,ko00001,ko01000,ko01011				Bacteria	1TPAU@1239,4H9KI@91061,COG0766@1,COG0766@2	NA|NA|NA	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AHPHCOMF_00185	264199.stu1169	1.9e-194	684.9	Bacilli	galE		5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQ7N@1239,4H9U5@91061,COG1087@1,COG1087@2	NA|NA|NA	M	Belongs to the NAD(P)-dependent epimerase dehydratase family
AHPHCOMF_00186	1161413.HMPREF1510_1936	3.5e-26	124.8	Bacilli													Bacteria	1TRPS@1239,4HCKB@91061,COG1874@1,COG1874@2	NA|NA|NA	G	Domain of unknown function (DUF4832)
AHPHCOMF_00187	322159.STER_1135	2.1e-203	714.9	Bacilli	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPCV@1239,4HB33@91061,COG0192@1,COG0192@2	NA|NA|NA	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AHPHCOMF_00188	322159.STER_1136	1.2e-174	619.0	Bacilli	birA	GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837	6.3.4.15	ko:K03524,ko:K04096	ko00780,ko01100,map00780,map01100		R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000				Bacteria	1TQCU@1239,4HB60@91061,COG0340@1,COG0340@2,COG1654@1,COG1654@2	NA|NA|NA	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
AHPHCOMF_00189	322159.STER_1138	4.1e-295	1020.0	Bacilli	dnaX	GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	2.7.7.7	ko:K02341,ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1TPS9@1239,4HAUE@91061,COG2812@1,COG2812@2	NA|NA|NA	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AHPHCOMF_00190	322159.STER_1139	6.1e-88	330.1	Bacilli	ytsP		1.8.4.14	ko:K08968	ko00270,map00270		R02025	RC00639	ko00000,ko00001,ko01000				Bacteria	1V6GQ@1239,4HH7X@91061,COG1956@1,COG1956@2	NA|NA|NA	T	GAF domain-containing protein
AHPHCOMF_00191	264199.stu1177	1.3e-165	589.0	Bacilli	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110		R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016				Bacteria	1TPSC@1239,4HAVW@91061,COG0324@1,COG0324@2	NA|NA|NA	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AHPHCOMF_00192	1046629.Ssal_01245	2.7e-19	100.5	Bacilli	WQ51_02665												Bacteria	1VPEZ@1239,2C91M@1,33E1E@2,4HRR2@91061	NA|NA|NA	S	Protein of unknown function (DUF3042)
AHPHCOMF_00195	264199.stu1179	8.5e-57	226.1	Bacilli	rplS	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02884	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V6FT@1239,4HIK3@91061,COG0335@1,COG0335@2	NA|NA|NA	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
AHPHCOMF_00196	322159.STER_1145	3.2e-220	770.8	Bacilli	XK27_05110												Bacteria	1TPX0@1239,4HBN3@91061,COG0038@1,COG0038@2	NA|NA|NA	P	chloride
AHPHCOMF_00197	264199.stu1181	8.7e-41	172.6	Bacteria	pheA	GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223	1.3.1.12,2.3.1.79,4.2.1.51,5.4.99.5	ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715,R01728	RC00125,RC00360,RC03116	ko00000,ko00001,ko00002,ko01000			iECNA114_1301.ECNA114_2667	Bacteria	COG1605@1,COG1605@2	NA|NA|NA	E	Chorismate mutase
AHPHCOMF_00198	264199.stu1182	3.7e-282	976.9	Bacilli	clcA	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006821,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015672,GO:0015698,GO:0015706,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0031404,GO:0034220,GO:0042802,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071705,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600		ko:K03281					ko00000	2.A.49		iAF1260.b0155,iB21_1397.B21_00153,iBWG_1329.BWG_0148,iE2348C_1286.E2348C_0162,iEC042_1314.EC042_0155,iEC55989_1330.EC55989_0149,iECBD_1354.ECBD_3463,iECDH10B_1368.ECDH10B_0135,iECDH1ME8569_1439.ECDH1ME8569_0149,iECD_1391.ECD_00154,iECIAI1_1343.ECIAI1_0153,iECO103_1326.ECO103_0155,iECSE_1348.ECSE_0156,iECUMN_1333.ECUMN_0152,iECW_1372.ECW_m0152,iEKO11_1354.EKO11_3761,iETEC_1333.ETEC_0151,iEcDH1_1363.EcDH1_3447,iEcE24377_1341.EcE24377A_0160,iEcolC_1368.EcolC_3504,iJO1366.b0155,iSSON_1240.SSON_0167,iUMNK88_1353.UMNK88_159,iWFL_1372.ECW_m0152,iY75_1357.Y75_RS00790,iZ_1308.Z0166	Bacteria	1TPX0@1239,4HD2H@91061,COG0038@1,COG0038@2	NA|NA|NA	P	Chloride transporter, ClC family
AHPHCOMF_00199	322159.STER_1148	2.3e-75	288.1	Bacilli	fld			ko:K03839					ko00000				Bacteria	1V7AG@1239,4HMJF@91061,COG0716@1,COG0716@2	NA|NA|NA	C	Flavodoxin
AHPHCOMF_00200	996306.SSUR61_0275	3.3e-14	84.7	Streptococcus suis	XK27_08880												Bacteria	1U92D@1239,1WTJN@1307,29R1H@1,30C2M@2,4IJ2X@91061	NA|NA|NA		
AHPHCOMF_00201	264199.stu1185	4.7e-126	457.2	Bacilli	XK27_08875												Bacteria	1VW9X@1239,4HWF8@91061,COG5549@1,COG5549@2	NA|NA|NA	O	Zinc-dependent metalloprotease
AHPHCOMF_00202	264199.stu1186	3.5e-151	540.8	Bacilli	estA			ko:K03930					ko00000,ko01000		CE1		Bacteria	1TPA9@1239,4IPZQ@91061,COG0627@1,COG0627@2	NA|NA|NA	S	Putative esterase
AHPHCOMF_00203	322159.STER_1152	7.8e-310	1068.9	Bacilli	rnjB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360		ko:K12574	ko03018,map03018				ko00000,ko00001,ko01000,ko03019				Bacteria	1TQ9G@1239,4HAAP@91061,COG0595@1,COG0595@2	NA|NA|NA	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AHPHCOMF_00204	264199.stu1188	1.2e-135	489.2	Bacilli	XK27_08845			ko:K05833		M00247			ko00000,ko00002,ko02000				Bacteria	1TPAN@1239,4HCHC@91061,COG1101@1,COG1101@2	NA|NA|NA	S	abc transporter atp-binding protein
AHPHCOMF_00205	322159.STER_1154	4e-148	530.8	Bacilli	XK27_08840			ko:K01989,ko:K05832		M00247			ko00000,ko00002,ko02000				Bacteria	1TPDJ@1239,4HBMY@91061,COG4120@1,COG4120@2	NA|NA|NA	S	Belongs to the binding-protein-dependent transport system permease family
AHPHCOMF_00206	322159.STER_1155	3.3e-178	630.9	Bacilli	XK27_08835			ko:K01989,ko:K05832		M00247			ko00000,ko00002,ko02000				Bacteria	1TPB0@1239,4HE7G@91061,COG2984@1,COG2984@2	NA|NA|NA	S	ABC transporter substrate binding protein
AHPHCOMF_00207	246201.SM12261_0398	1.6e-16	91.7	Streptococcus mitis													Bacteria	1U4JG@1239,2AHCZ@1,2TPZV@28037,317PX@2,4IEB9@91061	NA|NA|NA	S	Domain of unknown function (DUF4649)
AHPHCOMF_00209	888833.HMPREF9421_1411	1.1e-43	183.0	Bacilli				ko:K14194	ko05150,map05150				ko00000,ko00001				Bacteria	1TV1Y@1239,4HBHJ@91061,COG2373@1,COG2373@2,COG2931@1,COG2931@2	NA|NA|NA	Q	the current gene model (or a revised gene model) may contain a frame shift
AHPHCOMF_00210	888833.HMPREF9421_1411	7e-27	126.3	Bacilli				ko:K14194	ko05150,map05150				ko00000,ko00001				Bacteria	1TV1Y@1239,4HBHJ@91061,COG2373@1,COG2373@2,COG2931@1,COG2931@2	NA|NA|NA	Q	the current gene model (or a revised gene model) may contain a frame shift
AHPHCOMF_00213	264199.stu1196	3.9e-276	956.8	Bacilli	pyk	GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009986,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0022607,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065	2.7.1.40,2.7.7.4	ko:K00873,ko:K00958	ko00010,ko00230,ko00261,ko00450,ko00620,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00261,map00450,map00620,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050,M00176,M00596	R00200,R00430,R00529,R01138,R01858,R02320,R04929	RC00002,RC00015,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147			iECO103_1326.ECO103_1819,iPC815.YPO2393	Bacteria	1TPGG@1239,4H9VY@91061,COG0469@1,COG0469@2	NA|NA|NA	G	Belongs to the pyruvate kinase family
AHPHCOMF_00214	264199.stu1197	1.2e-188	665.6	Bacilli	pfkA	GO:0003674,GO:0003824,GO:0003872,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061615,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019			iYO844.BSU29190	Bacteria	1TPF4@1239,4HAPN@91061,COG0205@1,COG0205@2	NA|NA|NA	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
AHPHCOMF_00215	322159.STER_1165	0.0	2029.2	Bacilli	dnaE		2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1TPYG@1239,4H9T3@91061,COG0587@1,COG0587@2	NA|NA|NA	L	DNA polymerase
AHPHCOMF_00216	264199.stu1199	4.1e-152	543.9	Bacilli	sua5		2.7.7.87	ko:K07566			R10463	RC00745	ko00000,ko01000,ko03009,ko03016				Bacteria	1U3HQ@1239,4HFGZ@91061,COG0009@1,COG0009@2	NA|NA|NA	J	Belongs to the SUA5 family
AHPHCOMF_00217	264199.stu1200	1.2e-111	409.1	Bacilli	leuD		4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	1V1I6@1239,4HFTY@91061,COG0066@1,COG0066@2	NA|NA|NA	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AHPHCOMF_00218	322159.STER_1168	6.8e-275	952.6	Bacilli	leuC	GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000			iEcE24377_1341.EcE24377A_0075,iPC815.YPO0531,iSB619.SA_RS10700	Bacteria	1TPE5@1239,4HAWA@91061,COG0065@1,COG0065@2	NA|NA|NA	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AHPHCOMF_00219	322159.STER_1169	3.3e-43	180.6	Bacteria	ysdA												Bacteria	COG3326@1,COG3326@2	NA|NA|NA	L	Membrane
AHPHCOMF_00220	264199.stu1202	6.6e-190	669.8	Bacilli	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	1TPEM@1239,4HATP@91061,COG0473@1,COG0473@2	NA|NA|NA	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
AHPHCOMF_00221	322159.STER_1171	5.9e-291	1006.1	Bacilli	leuA		2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000			iSB619.SA_RS10690,iYO844.BSU28280	Bacteria	1TP4Y@1239,4HA6E@91061,COG0119@1,COG0119@2	NA|NA|NA	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AHPHCOMF_00222	264199.stu1204	4.6e-131	473.8	Bacilli	gpmA	GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147				Bacteria	1TQFP@1239,4HAW7@91061,COG0588@1,COG0588@2	NA|NA|NA	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AHPHCOMF_00223	322159.STER_1173	2.5e-180	637.9	Bacilli	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.98.1	ko:K00226,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01867,R01869	RC00051	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPFV@1239,4HBFE@91061,COG0167@1,COG0167@2	NA|NA|NA	F	Catalyzes the conversion of dihydroorotate to orotate
AHPHCOMF_00225	264199.stu1209	2.8e-39	167.5	Bacilli	hup			ko:K03530					ko00000,ko03032,ko03036,ko03400				Bacteria	1V9XQ@1239,4HKF2@91061,COG0776@1,COG0776@2	NA|NA|NA	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
AHPHCOMF_00226	322159.STER_1176	2.1e-84	318.5	Bacilli	ypmS												Bacteria	1VF0K@1239,4HIYN@91061,COG4698@1,COG4698@2	NA|NA|NA	S	Protein conserved in bacteria
AHPHCOMF_00227	264199.stu1211	6e-144	516.9	Bacteria	ypmR	GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0016298,GO:0016787,GO:0016788,GO:0052689											Bacteria	COG2755@1,COG2755@2	NA|NA|NA	E	lipolytic protein G-D-S-L family
AHPHCOMF_00228	322159.STER_1178	1e-148	532.7	Bacilli	DegV												Bacteria	1TRZ4@1239,4HBR8@91061,COG1307@1,COG1307@2	NA|NA|NA	S	DegV family
AHPHCOMF_00229	322159.STER_1179	5.8e-305	1052.7	Bacilli	recN	GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360		ko:K03631,ko:K13582	ko04112,map04112				ko00000,ko00001,ko03400				Bacteria	1TP99@1239,4H9ZR@91061,COG0497@1,COG0497@2	NA|NA|NA	L	May be involved in recombinational repair of damaged DNA
AHPHCOMF_00230	322159.STER_1180	1.8e-72	278.5	Bacilli	argR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141		ko:K03402					ko00000,ko03000				Bacteria	1V1R7@1239,4HFY8@91061,COG1438@1,COG1438@2	NA|NA|NA	K	Regulates arginine biosynthesis genes
AHPHCOMF_00231	264199.stu1215	4.3e-158	563.9	Bacilli	rrmJ		2.1.1.226,2.1.1.227	ko:K06442					ko00000,ko01000,ko03009				Bacteria	1TPE4@1239,4HAPY@91061,COG1189@1,COG1189@2	NA|NA|NA	J	Ribosomal RNA large subunit methyltransferase J
AHPHCOMF_00232	322159.STER_1182	3e-159	567.8	Bacilli	ispA	GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0071704,GO:1901576	2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90	ko:K00795,ko:K02523,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061,R09248	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006				Bacteria	1TPQY@1239,4HA8E@91061,COG0142@1,COG0142@2	NA|NA|NA	H	Belongs to the FPP GGPP synthase family
AHPHCOMF_00233	264199.stu1217	3.5e-29	133.7	Bacteria	xseB		3.1.11.6	ko:K03602	ko03430,map03430				ko00000,ko00001,ko01000,ko03400				Bacteria	COG1722@1,COG1722@2	NA|NA|NA	L	exodeoxyribonuclease VII activity
AHPHCOMF_00234	264199.stu1218	1.2e-247	862.1	Bacilli	xseA		3.1.11.6	ko:K03601	ko03430,map03430				ko00000,ko00001,ko01000,ko03400				Bacteria	1TP4E@1239,4HAN2@91061,COG1570@1,COG1570@2	NA|NA|NA	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AHPHCOMF_00237	264199.stu1220	3.4e-120	437.6	Bacilli	nth		4.2.99.18	ko:K10773	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	1TRAK@1239,4HATD@91061,COG0177@1,COG0177@2	NA|NA|NA	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AHPHCOMF_00238	264199.stu1221	2.9e-125	454.5	Bacteria	dnaD			ko:K02086					ko00000				Bacteria	COG3935@1,COG3935@2	NA|NA|NA		
AHPHCOMF_00239	322159.STER_1189	9.3e-183	646.0	Bacilli	metA	GO:0003674,GO:0003824,GO:0008374,GO:0008899,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQVR@1239,4H9W4@91061,COG1897@1,COG1897@2	NA|NA|NA	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AHPHCOMF_00240	264199.stu1223	2e-94	351.7	Bacilli	apt	GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.22,2.4.2.7	ko:K00759,ko:K03816,ko:K09685	ko00230,ko01100,ko01110,map00230,map01100,map01110		R00190,R01229,R02142,R04378	RC00063,RC00122	ko00000,ko00001,ko01000,ko03000,ko04147				Bacteria	1V1BV@1239,4HFUA@91061,COG0503@1,COG0503@2	NA|NA|NA	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AHPHCOMF_00241	322159.STER_1191	0.0	1449.1	Bacilli	recJ			ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1TPXE@1239,4H9UP@91061,COG0608@1,COG0608@2,COG4199@1,COG4199@2	NA|NA|NA	L	Single-strand DNA-specific exonuclease, C terminal domain
AHPHCOMF_00242	322159.STER_1192	6.7e-139	500.0	Bacilli	XK27_05435		1.1.1.100	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	1TSJ3@1239,4HDU5@91061,COG0300@1,COG0300@2	NA|NA|NA	S	Belongs to the short-chain dehydrogenases reductases (SDR) family
AHPHCOMF_00243	264199.stu1226	9.2e-175	619.4	Bacilli	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016891,GO:0016893,GO:0016896,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013				ko00000,ko00001,ko01000,ko03016				Bacteria	1TRGP@1239,4HABM@91061,COG1234@1,COG1234@2	NA|NA|NA	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
AHPHCOMF_00244	322159.STER_1194	4.2e-118	430.6	Bacilli	galT		2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000				Bacteria	1VY8D@1239,4HXPD@91061,COG4468@1,COG4468@2	NA|NA|NA	G	UDPglucose--hexose-1-phosphate uridylyltransferase
AHPHCOMF_00245	322159.STER_1195	1.4e-223	781.9	Bacilli	hflX	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877		ko:K03665					ko00000,ko03009				Bacteria	1TNZB@1239,4HACA@91061,COG2262@1,COG2262@2	NA|NA|NA	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AHPHCOMF_00246	322159.STER_1197	5.6e-240	836.6	Bacilli	rodA			ko:K05837					ko00000,ko03036				Bacteria	1TPGH@1239,4HAV4@91061,COG0772@1,COG0772@2	NA|NA|NA	D	Belongs to the SEDS family
AHPHCOMF_00247	322159.STER_1198	1.8e-50	204.9	Firmicutes	hisE	GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.4.19,3.6.1.31,5.3.1.16	ko:K01523,ko:K01814,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037,R04640	RC00002,RC00945,RC01055	ko00000,ko00001,ko00002,ko01000			iSB619.SA_RS14110,iYO844.BSU34860	Bacteria	1VB6S@1239,COG0140@1,COG0140@2	NA|NA|NA	E	Phosphoribosyl-ATP
AHPHCOMF_00248	322159.STER_1199	5.5e-61	240.0	Bacilli	hisI	GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.4.19,3.5.4.25,3.6.1.31,5.3.1.16	ko:K01496,ko:K01497,ko:K01814,ko:K11755	ko00340,ko00740,ko00790,ko01100,ko01110,ko01230,ko02024,map00340,map00740,map00790,map01100,map01110,map01230,map02024	M00026,M00125	R00425,R04035,R04037,R04640	RC00002,RC00293,RC00945,RC01055,RC02504	ko00000,ko00001,ko00002,ko01000			iECNA114_1301.ECNA114_0880,iECW_1372.ECW_m2186,iEKO11_1354.EKO11_1768,iHN637.CLJU_RS05760,iSB619.SA_RS14110,iUMN146_1321.UM146_06665,iWFL_1372.ECW_m2186	Bacteria	1UYNA@1239,4HA9R@91061,COG0139@1,COG0139@2	NA|NA|NA	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AHPHCOMF_00249	322159.STER_1200	5.8e-135	486.9	Bacilli	hisF	GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	3.5.4.19,3.6.1.31	ko:K01663,ko:K02500,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037,R04558	RC00002,RC00010,RC01055,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000			iECO111_1330.ECO111_2749,iEcolC_1368.EcolC_1617,iHN637.CLJU_RS05755,iLJ478.TM1036,iSB619.SA_RS14115,iYL1228.KPN_02481	Bacteria	1TP0W@1239,4HAAM@91061,COG0107@1,COG0107@2	NA|NA|NA	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
AHPHCOMF_00250	322159.STER_1201	1.9e-127	461.8	Bacilli	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_0388	Bacteria	1V1IR@1239,4HACP@91061,COG0106@1,COG0106@2	NA|NA|NA	E	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AHPHCOMF_00251	322159.STER_1202	6.3e-108	396.7	Bacilli	hisH			ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQT0@1239,4HHNQ@91061,COG0118@1,COG0118@2	NA|NA|NA	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AHPHCOMF_00252	322159.STER_1203	2.2e-105	388.3	Bacilli	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23,2.6.1.9,3.1.3.15,4.2.1.19	ko:K00013,ko:K00817,ko:K01089,ko:K01693	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R01158,R01163,R03012,R03013,R03243,R03457	RC00006,RC00017,RC00099,RC00242,RC00463,RC00888,RC00932	ko00000,ko00001,ko00002,ko01000,ko01007			iECO111_1330.ECO111_2746,iECS88_1305.ECS88_2121,iJN746.PP_0289,iLJ478.TM1039,iSB619.SA_RS14130,iUMNK88_1353.UMNK88_2570	Bacteria	1TRH7@1239,4HCFG@91061,COG0131@1,COG0131@2	NA|NA|NA	E	imidazoleglycerol-phosphate dehydratase
AHPHCOMF_00253	322159.STER_1204	1.2e-228	798.9	Bacilli	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23,1.1.1.308	ko:K00013,ko:K15509	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPAW@1239,4H9XK@91061,COG0141@1,COG0141@2	NA|NA|NA	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AHPHCOMF_00254	322159.STER_1205	1.4e-116	425.6	Bacilli	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000				Bacteria	1TSVZ@1239,4H9MH@91061,COG0040@1,COG0040@2	NA|NA|NA	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
AHPHCOMF_00255	322159.STER_1206	5.7e-183	646.7	Bacilli	hisZ		2.4.2.17,6.1.1.21	ko:K00765,ko:K01892,ko:K02502	ko00340,ko00970,ko01100,ko01110,ko01230,map00340,map00970,map01100,map01110,map01230	M00026,M00359,M00360	R01071,R03655	RC00055,RC00523,RC02819,RC03200	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1TPZZ@1239,4HBBA@91061,COG3705@1,COG3705@2	NA|NA|NA	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AHPHCOMF_00256	322159.STER_1207	4.1e-195	687.2	Bacilli	hisC		2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007			iJN678.hisC	Bacteria	1TPUV@1239,4HA1H@91061,COG0079@1,COG0079@2	NA|NA|NA	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AHPHCOMF_00258	264199.stu0038	6.6e-31	139.4	Firmicutes				ko:K07497					ko00000				Bacteria	1TQQY@1239,COG2801@1,COG2801@2	NA|NA|NA	L	Integrase core domain protein
AHPHCOMF_00259	322159.STER_1759	1.6e-55	221.9	Bacteria				ko:K07497					ko00000				Bacteria	COG2801@1,COG2801@2	NA|NA|NA	L	transposition
AHPHCOMF_00260	322159.STER_0016	8.2e-22	109.0	Firmicutes				ko:K07483					ko00000				Bacteria	1W68S@1239,COG2963@1,COG2963@2	NA|NA|NA	L	Transposase
AHPHCOMF_00261	322159.STER_1757	5.2e-36	156.8	Bacteria				ko:K07483					ko00000				Bacteria	COG2963@1,COG2963@2	NA|NA|NA	L	transposase activity
AHPHCOMF_00262	435842.HMPREF0848_00449	1.3e-22	111.7	Firmicutes	XK27_08085												Bacteria	1VM50@1239,2EJUK@1,33DJ8@2	NA|NA|NA		
AHPHCOMF_00263	322159.STER_1210	5.6e-92	343.6	Bacilli	XK27_08080		3.1.1.53	ko:K05970					ko00000,ko01000				Bacteria	1TR6Z@1239,4HGB0@91061,COG4632@1,COG4632@2	NA|NA|NA	G	Exopolysaccharide biosynthesis protein
AHPHCOMF_00264	1046629.Ssal_01327	2.3e-09	67.8	Bacilli	XK27_08080		3.1.1.53	ko:K05970					ko00000,ko01000				Bacteria	1TR6Z@1239,4HGB0@91061,COG4632@1,COG4632@2	NA|NA|NA	G	Exopolysaccharide biosynthesis protein
AHPHCOMF_00265	322159.STER_1212	2e-140	505.0	Bacilli	hisK		3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	1V77D@1239,4HGYX@91061,COG1387@1,COG1387@2	NA|NA|NA	E	Histidinol phosphatase and related hydrolases of the PHP family
AHPHCOMF_00266	322159.STER_1213	1.1e-121	442.6	Bacilli	ylfI												Bacteria	1VGZ1@1239,4HNTM@91061,COG4478@1,COG4478@2	NA|NA|NA	S	tigr01906
AHPHCOMF_00267	322159.STER_1214	5.9e-143	513.5	Bacilli	nagD		2.7.1.25,3.1.3.41	ko:K00860,ko:K01101	ko00230,ko00627,ko00920,ko01100,ko01120,map00230,map00627,map00920,map01100,map01120	M00176	R00509,R03024,R04928	RC00002,RC00078,RC00151	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQGM@1239,4HA3R@91061,COG0647@1,COG0647@2	NA|NA|NA	G	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
AHPHCOMF_00268	264199.stu1235	1.5e-143	515.4	Bacilli	fat		3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100		R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004				Bacteria	1V3RB@1239,4HHJ4@91061,COG3884@1,COG3884@2	NA|NA|NA	I	Acyl-ACP thioesterase
AHPHCOMF_00269	322159.STER_1216	4.1e-217	760.4	Bacilli	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576											Bacteria	1TPES@1239,4HA60@91061,COG0635@1,COG0635@2	NA|NA|NA	H	Involved in the biosynthesis of porphyrin-containing compound
AHPHCOMF_00272	264199.stu1242	1.9e-205	721.5	Bacilli	rfbB	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901576	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPWM@1239,4HA3Y@91061,COG1088@1,COG1088@2	NA|NA|NA	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
AHPHCOMF_00273	264199.stu1243	8.3e-113	412.9	Bacilli	rmlC		1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000				Bacteria	1TRVB@1239,4HFQB@91061,COG1898@1,COG1898@2	NA|NA|NA	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
AHPHCOMF_00274	322159.STER_1224	4.1e-161	573.9	Bacilli	rfbA	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005996,GO:0006006,GO:0006139,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009117,GO:0009141,GO:0009147,GO:0009200,GO:0009211,GO:0009219,GO:0009225,GO:0009226,GO:0009262,GO:0009394,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019299,GO:0019300,GO:0019305,GO:0019318,GO:0019319,GO:0019438,GO:0019637,GO:0019692,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0045226,GO:0046075,GO:0046364,GO:0046379,GO:0046383,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000			iNJ661.Rv0334	Bacteria	1V301@1239,4H9R0@91061,COG1209@1,COG1209@2	NA|NA|NA	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AHPHCOMF_00275	264199.stu1245	1.1e-206	725.7	Bacilli	yurR	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114	1.4.5.1	ko:K00285	ko00360,map00360		R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000				Bacteria	1TQTF@1239,4HA0F@91061,COG0665@1,COG0665@2	NA|NA|NA	E	oxidoreductase
AHPHCOMF_00276	1046629.Ssal_01342	6.3e-101	373.6	Bacilli	zupT			ko:K07238					ko00000,ko02000	2.A.5.5			Bacteria	1TP7J@1239,4HB3R@91061,COG0428@1,COG0428@2	NA|NA|NA	P	Mediates zinc uptake. May also transport other divalent cations
AHPHCOMF_00277	264199.stu1248	9.6e-149	532.7	Bacilli	yqfO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.5.4.16	ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQ27@1239,4H9NY@91061,COG0327@1,COG0327@2	NA|NA|NA	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AHPHCOMF_00278	322159.STER_1228	2.7e-123	448.0	Bacilli	trmK	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.217	ko:K06967					ko00000,ko01000,ko03016				Bacteria	1V3I4@1239,4HHIM@91061,COG2384@1,COG2384@2	NA|NA|NA	S	SAM-dependent methyltransferase
AHPHCOMF_00279	264199.stu1250	1.7e-70	271.9	Bacilli	gtrA	GO:0000166,GO:0003674,GO:0003824,GO:0003870,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009987,GO:0016020,GO:0016410,GO:0016491,GO:0016620,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0016903,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576											Bacteria	1VMS6@1239,4HNB7@91061,COG2246@1,COG2246@2	NA|NA|NA	S	GtrA-like protein
AHPHCOMF_00280	264199.stu1251	1.5e-250	871.7	Bacilli	glmM	GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130		R02060	RC00408	ko00000,ko00001,ko01000			iSB619.SA_RS11275,iSBO_1134.SBO_3206	Bacteria	1TP1X@1239,4HB16@91061,COG1109@1,COG1109@2	NA|NA|NA	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AHPHCOMF_00281	322159.STER_1231	6e-169	600.1	Bacilli	ybbR	GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009											Bacteria	1TSIV@1239,4HD8Y@91061,COG4856@1,COG4856@2	NA|NA|NA	S	Protein conserved in bacteria
AHPHCOMF_00282	264199.stu1253	5.6e-124	450.3	Bacilli	dacA	GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	2.7.7.85	ko:K18672					ko00000,ko01000				Bacteria	1TPRW@1239,4H9XZ@91061,COG1624@1,COG1624@2	NA|NA|NA	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AHPHCOMF_00283	264199.stu1254	1.8e-253	881.3	Bacilli	murD		3.4.21.10,6.3.2.13,6.3.2.9	ko:K01317,ko:K01925,ko:K01928,ko:K01932	ko00300,ko00471,ko00550,ko01100,map00300,map00471,map00550,map01100		R02783,R02788	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01002,ko01011,ko04131				Bacteria	1UHPI@1239,4HVP0@91061,COG0771@1,COG0771@2	NA|NA|NA	M	Mur ligase, middle domain protein
AHPHCOMF_00284	264199.stu1255	8.7e-150	536.2	Bacilli	cobQ			ko:K07009					ko00000				Bacteria	1U7I9@1239,4HD1P@91061,COG3442@1,COG3442@2	NA|NA|NA	S	glutamine amidotransferase
AHPHCOMF_00285	264199.stu1256	0.0	1643.2	Bacilli	mprF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.3.2.3	ko:K07027,ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726			ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	2.A.1.3.37,4.D.2		iYO844.BG12900	Bacteria	1TQI2@1239,4HBHU@91061,COG0392@1,COG0392@2,COG2898@1,COG2898@2	NA|NA|NA	J	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AHPHCOMF_00286	264199.stu1257	1.4e-130	472.2	Bacilli	pip		1.11.1.10	ko:K00433					ko00000,ko01000				Bacteria	1V02M@1239,4HN2K@91061,COG0596@1,COG0596@2	NA|NA|NA	S	Alpha beta hydrolase
AHPHCOMF_00288	264199.stu1259	0.0	1203.0	Bacilli	uup			ko:K06158					ko00000,ko03012				Bacteria	1TPAX@1239,4HBVV@91061,COG0488@1,COG0488@2	NA|NA|NA	S	abc transporter atp-binding protein
AHPHCOMF_00289	264199.stu1260	2.1e-114	418.3	Bacilli	udk	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100		R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000			iSBO_1134.SBO_0893	Bacteria	1TQ4V@1239,4HAVR@91061,COG0572@1,COG0572@2	NA|NA|NA	F	Cytidine monophosphokinase
AHPHCOMF_00290	322159.STER_1239	2.1e-178	631.7	Bacilli	yfmL	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K05592,ko:K18692	ko03018,map03018				ko00000,ko00001,ko01000,ko03009,ko03019				Bacteria	1TQ9R@1239,4HANR@91061,COG0513@1,COG0513@2	NA|NA|NA	L	DEAD DEAH box helicase
AHPHCOMF_00291	322159.STER_1240	2.1e-28	131.0	Bacteria			6.3.2.2,6.3.2.4	ko:K01919,ko:K01921	ko00270,ko00473,ko00480,ko00550,ko01100,ko01502,map00270,map00473,map00480,map00550,map01100,map01502	M00118	R00894,R01150,R10993	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011				Bacteria	COG1181@1,COG1181@2	NA|NA|NA	F	Belongs to the D-alanine--D-alanine ligase family
AHPHCOMF_00292	264199.stu1263	8.6e-265	919.1	Bacilli	gapN	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0043891,GO:0047100,GO:0055114	1.2.1.9	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	M00308,M00633	R01058	RC00242	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP4S@1239,4H9MF@91061,COG1012@1,COG1012@2	NA|NA|NA	C	Belongs to the aldehyde dehydrogenase family
AHPHCOMF_00293	322159.STER_1692	1.6e-249	868.2	Bacilli				ko:K07485					ko00000				Bacteria	1TQ93@1239,4HJK9@91061,COG3464@1,COG3464@2	NA|NA|NA	L	Transposase
AHPHCOMF_00294	322159.STER_1242	0.0	1092.0	Bacilli	ptsI	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0008150,GO:0008643,GO:0008965,GO:0009401,GO:0016740,GO:0016772,GO:0016775,GO:0019197,GO:0032991,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051179,GO:0051234,GO:0071702	2.7.3.9	ko:K08483	ko02060,map02060				ko00000,ko00001,ko01000,ko02000	8.A.7		iB21_1397.B21_02277,iE2348C_1286.E2348C_2602,iEC042_1314.EC042_2625,iECBD_1354.ECBD_1265,iECB_1328.ECB_02316,iECD_1391.ECD_02316,iECH74115_1262.ECH74115_3647,iECIAI1_1343.ECIAI1_2474,iECIAI39_1322.ECIAI39_2562,iECO103_1326.ECO103_2935,iECO111_1330.ECO111_3146,iECO26_1355.ECO26_3469,iECP_1309.ECP_2440,iECSE_1348.ECSE_2707,iECSP_1301.ECSP_3364,iECUMN_1333.ECUMN_2738,iECW_1372.ECW_m2645,iECs_1301.ECs3288,iEKO11_1354.EKO11_1312,iEcE24377_1341.EcE24377A_2703,iEcHS_1320.EcHS_A2551,iEcSMS35_1347.EcSMS35_2571,iEcolC_1368.EcolC_1262,iLF82_1304.LF82_1770,iNRG857_1313.NRG857_12115,iSBO_1134.SBO_2440,iSDY_1059.SDY_2613,iSFV_1184.SFV_2468,iSF_1195.SF2471,iSFxv_1172.SFxv_2720,iSSON_1240.SSON_2505,iS_1188.S2617,iUMNK88_1353.UMNK88_3018,iWFL_1372.ECW_m2645,iZ_1308.Z3682	Bacteria	1TPK8@1239,4H9VD@91061,COG1080@1,COG1080@2	NA|NA|NA	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AHPHCOMF_00295	264199.stu1265	7.9e-39	166.0	Bacilli	ptsH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007		ko:K11189					ko00000,ko02000	4.A.2.1			Bacteria	1VA0R@1239,4HKGA@91061,COG1925@1,COG1925@2	NA|NA|NA	G	phosphocarrier protein Hpr
AHPHCOMF_00296	264199.stu1266	9.7e-222	775.8	Bacilli	icd	GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000			e_coli_core.b1136,iAF1260.b1136,iECDH1ME8569_1439.ECDH1ME8569_1071,iEcDH1_1363.EcDH1_2511,iJN746.PP_4011,iJO1366.b1136,iJR904.b1136,iY75_1357.Y75_RS05930,iYL1228.KPN_01144	Bacteria	1UHPE@1239,4H9US@91061,COG0538@1,COG0538@2	NA|NA|NA	C	Isocitrate dehydrogenase
AHPHCOMF_00297	264199.stu1267	4.3e-211	740.3	Bacilli	citZ		2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	1TPPS@1239,4H9YE@91061,COG0372@1,COG0372@2	NA|NA|NA	C	Belongs to the citrate synthase family
AHPHCOMF_00298	264199.stu1268	0.0	1756.1	Bacilli	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000			iSB619.SA_RS06730	Bacteria	1VTMM@1239,4HB5N@91061,COG1048@1,COG1048@2	NA|NA|NA	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AHPHCOMF_00299	264199.stu1269	8.5e-34	149.1	Bacilli	nrdH	GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009893,GO:0009987,GO:0016491,GO:0019222,GO:0019725,GO:0022900,GO:0042592,GO:0043085,GO:0044093,GO:0044237,GO:0045454,GO:0048518,GO:0050789,GO:0050790,GO:0050794,GO:0051341,GO:0051353,GO:0055114,GO:0065007,GO:0065008,GO:0065009		ko:K06191					ko00000				Bacteria	1VEFX@1239,4HNUX@91061,COG0695@1,COG0695@2	NA|NA|NA	O	Glutaredoxin
AHPHCOMF_00300	264199.stu1270	0.0	1435.6	Bacilli	nrdE		1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400			iYO844.BSU17380	Bacteria	1TPFH@1239,4H9X0@91061,COG0209@1,COG0209@2	NA|NA|NA	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AHPHCOMF_00301	264199.stu1271	1.7e-184	651.7	Bacilli	nrdF		1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400				Bacteria	1TQTH@1239,4H9WX@91061,COG0208@1,COG0208@2	NA|NA|NA	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AHPHCOMF_00303	264199.stu1273	1.9e-71	275.0	Bacteria													Bacteria	COG3547@1,COG3547@2	NA|NA|NA	L	Transposase (IS116 IS110 IS902 family)
AHPHCOMF_00304	264199.stu1274	3.6e-61	240.7	Bacteria													Bacteria	COG3547@1,COG3547@2	NA|NA|NA	L	Transposase (IS116 IS110 IS902 family)
AHPHCOMF_00305	264199.stu1275	6.9e-165	586.6	Bacilli	ypuA												Bacteria	1TR2I@1239,4HBVZ@91061,COG4086@1,COG4086@2	NA|NA|NA	S	secreted protein
AHPHCOMF_00306	322159.STER_1254	1.4e-71	275.4	Bacilli	yaeR			ko:K08234					ko00000				Bacteria	1V6XU@1239,4HIFI@91061,COG0346@1,COG0346@2	NA|NA|NA	E	COG0346 Lactoylglutathione lyase and related lyases
AHPHCOMF_00307	322159.STER_1255	1.7e-134	485.3	Bacilli	srtA		3.4.22.70	ko:K07284					ko00000,ko01000,ko01002,ko01011				Bacteria	1V83Z@1239,4HIA0@91061,COG3764@1,COG3764@2	NA|NA|NA	M	Sortase (surface protein transpeptidase)
AHPHCOMF_00308	322159.STER_1256	0.0	1427.5	Bacilli	gyrA	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	5.99.1.3	ko:K02469,ko:K02621					ko00000,ko01000,ko02048,ko03032,ko03036,ko03400				Bacteria	1TP2Z@1239,4HAHY@91061,COG0188@1,COG0188@2	NA|NA|NA	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AHPHCOMF_00309	264199.stu1280	7e-181	639.8	Bacilli	ldh		1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922		R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147				Bacteria	1TPSY@1239,4HB0Z@91061,COG0039@1,COG0039@2	NA|NA|NA	C	Belongs to the LDH MDH superfamily. LDH family
AHPHCOMF_00310	264199.stu1281	2.6e-258	897.5	Bacilli	noxE												Bacteria	1TPWW@1239,4H9U7@91061,COG0446@1,COG0446@2	NA|NA|NA	P	NADH oxidase
AHPHCOMF_00311	264199.stu1282	9.5e-294	1015.4	Bacilli	yfmM			ko:K06158					ko00000,ko03012				Bacteria	1TPAX@1239,4HC58@91061,COG0488@1,COG0488@2	NA|NA|NA	S	abc transporter atp-binding protein
AHPHCOMF_00312	322159.STER_1260	6.7e-83	313.5	Bacilli	XK27_01265			ko:K16923		M00582			ko00000,ko00002,ko02000	3.A.1.28			Bacteria	1VC0F@1239,4HMJM@91061,COG4720@1,COG4720@2	NA|NA|NA	S	ECF-type riboflavin transporter, S component
AHPHCOMF_00313	264199.stu1284	3.5e-86	324.3	Bacilli	pdxK		2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100		R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000				Bacteria	1TRCR@1239,4HHME@91061,COG2240@1,COG2240@2	NA|NA|NA	H	Belongs to the pyridoxine kinase family
AHPHCOMF_00314	264199.stu1284	4.5e-44	183.7	Bacilli	pdxK		2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100		R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000				Bacteria	1TRCR@1239,4HHME@91061,COG2240@1,COG2240@2	NA|NA|NA	H	Belongs to the pyridoxine kinase family
AHPHCOMF_00315	264199.stu1285	2e-86	325.1	Firmicutes													Bacteria	1V6QK@1239,COG4720@1,COG4720@2	NA|NA|NA	S	ECF-type riboflavin transporter, S component
AHPHCOMF_00317	322159.STER_1264	5e-240	836.6	Bacilli	XK27_08130												Bacteria	1TPS5@1239,4HBNK@91061,COG1167@1,COG1167@2	NA|NA|NA	K	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
AHPHCOMF_00318	264199.stu1289	2e-55	221.5	Firmicutes	nrdD_1		1.1.98.6,1.17.4.1	ko:K00525,ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024,R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400				Bacteria	1TT3U@1239,COG0209@1,COG0209@2	NA|NA|NA	F	Ribonucleoside-triphosphate reductase
AHPHCOMF_00321	264199.stu1292	0.0	1562.7	Bacilli	pheT	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890,ko:K06878	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iG2583_1286.G2583_2160,iPC815.YPO2428	Bacteria	1TP98@1239,4HAQ9@91061,COG0072@1,COG0072@2,COG0073@1,COG0073@2	NA|NA|NA	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AHPHCOMF_00322	264199.stu1293	9.9e-94	349.4	Bacilli	paiA		2.3.1.57	ko:K22441					ko00000,ko01000				Bacteria	1VDFK@1239,4HMHW@91061,COG0454@1,COG0456@2	NA|NA|NA	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AHPHCOMF_00323	264199.stu1294	9.6e-197	692.6	Bacilli	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1TPFW@1239,4HAVN@91061,COG0016@1,COG0016@2	NA|NA|NA	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AHPHCOMF_00324	322159.STER_1271	0.0	1413.7	Bacilli	smc			ko:K03529					ko00000,ko03036				Bacteria	1TPJV@1239,4HB89@91061,COG1196@1,COG1196@2	NA|NA|NA	D	Required for chromosome condensation and partitioning
AHPHCOMF_00325	322159.STER_1272	8.4e-125	453.0	Bacilli	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205				ko00000,ko00001,ko01000,ko03009,ko03019,ko03036				Bacteria	1TPGC@1239,4HAWU@91061,COG0571@1,COG0571@2	NA|NA|NA	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
AHPHCOMF_00326	322159.STER_1273	6.6e-173	613.2	Bacilli	dapA		4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPCK@1239,4H9K9@91061,COG0329@1,COG0329@2	NA|NA|NA	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AHPHCOMF_00327	322159.STER_1274	1.1e-198	699.1	Bacilli	asd		1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPC6@1239,4HA9H@91061,COG0136@1,COG0136@2	NA|NA|NA	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AHPHCOMF_00328	322159.STER_1276	2.4e-92	344.7	Bacilli	pat		2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130		R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000				Bacteria	1V6X5@1239,4HIP1@91061,COG1247@1,COG1247@2	NA|NA|NA	M	acetyltransferase
AHPHCOMF_00329	904306.HMPREF9192_0265	1.1e-12	78.2	Bacteria													Bacteria	COG3464@1,COG3464@2	NA|NA|NA		
AHPHCOMF_00330	264199.stu1305	3.4e-277	960.3	Bacilli	cls			ko:K06131,ko:K06915	ko00564,ko01100,map00564,map01100		R07390	RC00017	ko00000,ko00001,ko01000				Bacteria	1TPKY@1239,4H9TI@91061,COG1502@1,COG1502@2	NA|NA|NA	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AHPHCOMF_00331	322159.STER_1280	0.0	1195.6	Bacilli	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391		ko:K03703	ko03420,map03420				ko00000,ko00001,ko03400				Bacteria	1TP4B@1239,4H9QH@91061,COG0322@1,COG0322@2	NA|NA|NA	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
AHPHCOMF_00332	322159.STER_1281	3.1e-127	461.1	Bacilli	yjjG	GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006206,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008655,GO:0009058,GO:0009112,GO:0009410,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019856,GO:0019859,GO:0030145,GO:0034641,GO:0034654,GO:0042221,GO:0042578,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.1.3.102,3.1.3.104,3.1.3.5,3.8.1.2	ko:K01560,ko:K07025,ko:K08723,ko:K20862	ko00230,ko00240,ko00361,ko00625,ko00740,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00740,map00760,map01100,map01110,map01120	M00125	R00183,R00511,R00548,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287,R07280	RC00017,RC00697	ko00000,ko00001,ko00002,ko01000			iECNA114_1301.ECNA114_4614	Bacteria	1TWM7@1239,4HEXU@91061,COG1011@1,COG1011@2	NA|NA|NA	E	hydrolase
AHPHCOMF_00333	435842.HMPREF0848_00873	1.2e-62	246.1	Bacteria	bioY			ko:K03523	ko02010,map02010	M00581,M00582			ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2			Bacteria	COG1268@1,COG1268@2	NA|NA|NA	S	biotin transmembrane transporter activity
AHPHCOMF_00334	264199.stu1309	2e-88	332.0	Bacilli	proW			ko:K05846	ko02010,map02010	M00209			ko00000,ko00001,ko00002,ko02000	3.A.1.12			Bacteria	1V24D@1239,4IQR7@91061,COG1174@1,COG1174@2	NA|NA|NA	P	Binding-protein-dependent transport system inner membrane component
AHPHCOMF_00335	264199.stu1310	1.6e-137	495.4	Bacilli	proV			ko:K05847	ko02010,map02010	M00209			ko00000,ko00001,ko00002,ko02000	3.A.1.12			Bacteria	1TPV8@1239,4H9SI@91061,COG1125@1,COG1125@2	NA|NA|NA	E	abc transporter atp-binding protein
AHPHCOMF_00336	264199.stu1311	3.8e-165	587.4	Bacilli	proX			ko:K05845	ko02010,map02010	M00209			ko00000,ko00001,ko00002,ko02000	3.A.1.12			Bacteria	1TQ7D@1239,4HESS@91061,COG1732@1,COG1732@2	NA|NA|NA	M	ABC transporter, substrate-binding protein, QAT family
AHPHCOMF_00337	264199.stu1312	2.3e-103	381.7	Bacilli	proWZ			ko:K05846	ko02010,map02010	M00209			ko00000,ko00001,ko00002,ko02000	3.A.1.12			Bacteria	1V41S@1239,4HH8U@91061,COG1174@1,COG1174@2	NA|NA|NA	P	ABC transporter (Permease
AHPHCOMF_00338	264199.stu1313	2.5e-278	964.1	Bacilli	hutH		4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPCW@1239,4H9YS@91061,COG2986@1,COG2986@2	NA|NA|NA	E	Histidine ammonia-lyase
AHPHCOMF_00339	264199.stu1314	1.6e-205	721.8	Bacilli				ko:K09703					ko00000				Bacteria	1TR39@1239,4HBM2@91061,COG3535@1,COG3535@2	NA|NA|NA	S	Protein of unknown function (DUF917)
AHPHCOMF_00340	264199.stu1315	2.5e-308	1063.9	Bacilli	hutU		4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPZ9@1239,4H9NH@91061,COG2987@1,COG2987@2	NA|NA|NA	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AHPHCOMF_00341	264199.stu1316	1.6e-59	235.7	Bacilli	sdaAB		4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230		R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000				Bacteria	1U8TZ@1239,4HBD6@91061,COG1760@1,COG1760@2	NA|NA|NA	E	L-serine dehydratase
AHPHCOMF_00342	904306.HMPREF9192_1103	4.4e-101	374.0	Bacilli	desR			ko:K02479,ko:K07693	ko02020,map02020	M00479			ko00000,ko00001,ko00002,ko02022				Bacteria	1TVTF@1239,4HAJW@91061,COG2197@1,COG2197@2	NA|NA|NA	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AHPHCOMF_00343	435842.HMPREF0848_00889	1.5e-184	652.1	Bacilli	desK	GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	2.7.13.3	ko:K07778	ko02020,map02020	M00479			ko00000,ko00001,ko00002,ko01000,ko01001,ko02022				Bacteria	1TSUE@1239,4HB9N@91061,COG4585@1,COG4585@2	NA|NA|NA	T	Histidine kinase
AHPHCOMF_00344	264199.stu1327	1.2e-132	479.2	Firmicutes	yvfS			ko:K01992		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1V1AU@1239,COG0842@1,COG0842@2	NA|NA|NA	V	ABC-2 type transporter
AHPHCOMF_00345	264199.stu1328	5.3e-156	557.0	Bacilli	XK27_09825			ko:K01990		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1UZ04@1239,4HDGQ@91061,COG1131@1,COG1131@2	NA|NA|NA	V	abc transporter atp-binding protein
AHPHCOMF_00349	322159.STER_1296	6.6e-213	746.5	Bacilli													Bacteria	1UG5D@1239,2ZBIK@2,4H9W5@91061,COG0477@1	NA|NA|NA	EGP	Major facilitator Superfamily
AHPHCOMF_00350	322159.STER_1297	0.0	1530.8	Bacteria			2.7.7.73,2.7.7.80	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122		R07459	RC00043	ko00000,ko00001,ko01000				Bacteria	COG0476@1,COG0476@2,COG1164@1,COG1164@2	NA|NA|NA	E	metalloendopeptidase activity
AHPHCOMF_00351	322159.STER_1299	1.2e-152	545.8	Bacilli	mutR			ko:K20373	ko02024,map02024				ko00000,ko00001,ko03000				Bacteria	1VBRX@1239,4HMPG@91061,COG1396@1,COG1396@2	NA|NA|NA	K	Transcriptional activator, Rgg GadR MutR family
AHPHCOMF_00352	1121864.OMO_01808	4.6e-42	177.2	Bacilli			3.6.1.55	ko:K03574					ko00000,ko01000,ko03400				Bacteria	1UJTM@1239,4ITFG@91061,COG1051@1,COG1051@2	NA|NA|NA	F	NUDIX domain
AHPHCOMF_00354	322159.STER_1302	3.7e-122	444.1	Bacilli													Bacteria	1VG0A@1239,2DQZH@1,339IV@2,4HTJB@91061	NA|NA|NA	S	An automated process has identified a potential problem with this gene model
AHPHCOMF_00355	435842.HMPREF0848_00905	6.1e-26	123.2	Firmicutes	XK27_09825			ko:K01990		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1UZ04@1239,COG1131@1,COG1131@2	NA|NA|NA	V	'abc transporter, ATP-binding protein
AHPHCOMF_00356	1123300.AUIN01000013_gene1665	1.4e-15	90.1	Bacteria	liaI			ko:K11619	ko02020,map02020	M00754			ko00000,ko00001,ko00002				Bacteria	COG4758@1,COG4758@2	NA|NA|NA	KT	membrane
AHPHCOMF_00357	1123300.AUIN01000013_gene1665	2.6e-30	139.0	Bacteria	liaI			ko:K11619	ko02020,map02020	M00754			ko00000,ko00001,ko00002				Bacteria	COG4758@1,COG4758@2	NA|NA|NA	KT	membrane
AHPHCOMF_00358	322159.STER_1306	6e-99	366.7	Firmicutes	XK27_05000			ko:K06940					ko00000				Bacteria	1V67G@1239,COG0727@1,COG0727@2	NA|NA|NA	S	Fe-S-cluster oxidoreductase
AHPHCOMF_00359	264199.stu1333	0.0	1138.6	Bacilli				ko:K02004,ko:K19084	ko02010,ko02020,map02010,map02020	M00258,M00731,M00737			ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.134			Bacteria	1TR2D@1239,4H9SH@91061,COG0577@1,COG0577@2	NA|NA|NA	V	ABC transporter (permease)
AHPHCOMF_00360	322159.STER_1308	1.9e-133	481.9	Bacilli	macB2			ko:K02003		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	1TNZG@1239,4H9UT@91061,COG1136@1,COG1136@2	NA|NA|NA	V	ABC transporter, ATP-binding protein
AHPHCOMF_00361	264199.stu1335	9e-165	586.3	Bacilli													Bacteria	1TQSG@1239,4HG2J@91061,COG0642@1,COG0642@2	NA|NA|NA	T	Histidine kinase
AHPHCOMF_00362	904306.HMPREF9192_1091	2e-123	448.4	Bacilli													Bacteria	1TR32@1239,4HAUJ@91061,COG0745@1,COG0745@2	NA|NA|NA	KT	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AHPHCOMF_00363	904306.HMPREF9192_1089	2e-77	295.0	Bacilli	xpt	GO:0003674,GO:0003824,GO:0006139,GO:0006166,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046128,GO:0046129,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.22,2.4.2.7	ko:K00759,ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110		R00190,R01229,R02142,R04378	RC00063,RC00122	ko00000,ko00001,ko01000,ko04147			iYO844.BSU22070	Bacteria	1V1DU@1239,4HFNW@91061,COG0503@1,COG0503@2	NA|NA|NA	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
AHPHCOMF_00364	904306.HMPREF9192_1088	3.3e-69	267.7	Bacilli	pbuX	GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823		ko:K03458,ko:K16169,ko:K16170					ko00000,ko02000	2.A.40,2.A.40.3.1,2.A.40.3.2		iSB619.SA_RS02140	Bacteria	1TNZZ@1239,4HBAM@91061,COG2233@1,COG2233@2	NA|NA|NA	F	xanthine permease
AHPHCOMF_00365	264199.stu1340	9.2e-119	433.0	Bacilli	pbuX	GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823		ko:K02824,ko:K03458,ko:K16169,ko:K16170					ko00000,ko02000	2.A.40,2.A.40.1.1,2.A.40.1.2,2.A.40.3.1,2.A.40.3.2		iSB619.SA_RS02140	Bacteria	1TNZZ@1239,4HBAM@91061,COG2233@1,COG2233@2	NA|NA|NA	F	xanthine permease
AHPHCOMF_00366	322159.STER_1313	4.5e-247	860.1	Bacilli	norM	GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085		ko:K03327					ko00000,ko02000	2.A.66.1			Bacteria	1TP5U@1239,4HA4W@91061,COG0534@1,COG0534@2	NA|NA|NA	V	Multidrug efflux pump
AHPHCOMF_00367	264199.stu1343	9.7e-188	662.5	Bacilli	msrA		1.8.4.11,1.8.4.12	ko:K07304,ko:K07305,ko:K12267					ko00000,ko01000				Bacteria	1TQ3E@1239,4HAIV@91061,COG0225@1,COG0225@2,COG0229@1,COG0229@2	NA|NA|NA	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AHPHCOMF_00368	264199.stu1357	1.7e-235	821.6	Bacilli	brnQ	GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903785,GO:1903825,GO:1905039		ko:K03311					ko00000	2.A.26			Bacteria	1TQIS@1239,4HAKA@91061,COG1114@1,COG1114@2	NA|NA|NA	E	Component of the transport system for branched-chain amino acids
AHPHCOMF_00369	264199.stu1358	1.9e-65	255.0	Bacilli	manA		5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000				Bacteria	1VRGI@1239,4HBFW@91061,COG1482@1,COG1482@2	NA|NA|NA	G	mannose-6-phosphate isomerase
AHPHCOMF_00370	264199.stu1359	8.2e-57	226.1	Bacilli	manA		5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000				Bacteria	1VRGI@1239,4HBFW@91061,COG1482@1,COG1482@2	NA|NA|NA	G	mannose-6-phosphate isomerase
AHPHCOMF_00371	264199.stu1360	4.8e-25	119.8	Bacteria	csbD												Bacteria	COG3237@1,COG3237@2	NA|NA|NA	K	CsbD-like
AHPHCOMF_00372	264199.stu1361	6.2e-228	796.6	Bacilli	yfnA			ko:K03294					ko00000	2.A.3.2			Bacteria	1TQ4K@1239,4HA66@91061,COG0531@1,COG0531@2	NA|NA|NA	E	amino acid
AHPHCOMF_00373	264199.stu1363	5.7e-109	400.2	Bacilli	XK27_02070			ko:K07078					ko00000				Bacteria	1V1CR@1239,4HD6W@91061,COG3560@1,COG3560@2	NA|NA|NA	S	nitroreductase
AHPHCOMF_00374	322159.STER_1320	1.2e-138	499.2	Bacilli			1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPRF@1239,4HAE7@91061,COG2514@1,COG2514@2	NA|NA|NA	S	glyoxalase
AHPHCOMF_00375	264199.stu1366	5.6e-77	293.5	Bacilli	ywnA												Bacteria	1V6FK@1239,4HKZD@91061,COG1959@1,COG1959@2	NA|NA|NA	K	Transcriptional regulator
AHPHCOMF_00376	322159.STER_1322	9.5e-158	562.8	Bacilli													Bacteria	1V13S@1239,4HENM@91061,COG4814@1,COG4814@2	NA|NA|NA	E	Alpha/beta hydrolase of unknown function (DUF915)
AHPHCOMF_00377	322159.STER_1323	1.1e-231	808.9	Bacilli	pts13C			ko:K02761	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.3.2			Bacteria	1V5SI@1239,4HJTK@91061,COG1455@1,COG1455@2	NA|NA|NA	G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AHPHCOMF_00378	264199.stu1369	2.2e-111	408.3	Bacilli	drgA												Bacteria	1UYJU@1239,4HBVQ@91061,COG0778@1,COG0778@2	NA|NA|NA	C	Nitroreductase
AHPHCOMF_00379	322159.STER_1325	4.2e-96	357.5	Firmicutes	yoaK												Bacteria	1V9ME@1239,COG3619@1,COG3619@2	NA|NA|NA	S	Protein of unknown function (DUF1275)
AHPHCOMF_00380	264199.stu1371	1.5e-160	572.0	Bacilli	yvgN												Bacteria	1TPM1@1239,4HARE@91061,COG0656@1,COG0656@2	NA|NA|NA	C	reductase
AHPHCOMF_00381	904306.HMPREF9192_1063	1e-181	642.5	Bacilli	galE		5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQ7N@1239,4H9U5@91061,COG1087@1,COG1087@2	NA|NA|NA	M	Belongs to the NAD(P)-dependent epimerase dehydratase family
AHPHCOMF_00382	322159.STER_1332	3.6e-282	976.9	Bacilli	XK27_07020												Bacteria	1TQYE@1239,4HDNX@91061,COG4868@1,COG4868@2	NA|NA|NA	S	Belongs to the UPF0371 family
AHPHCOMF_00384	264199.stu1379	1.1e-37	162.2	Bacteria	BP1961												Bacteria	COG4097@1,COG4097@2	NA|NA|NA	P	nitric oxide dioxygenase activity
AHPHCOMF_00385	1203590.HMPREF1481_01686	1.8e-54	218.4	Bacilli													Bacteria	1V4S4@1239,4HH0U@91061,COG0745@1,COG0745@2	NA|NA|NA	K	response regulator
AHPHCOMF_00386	904306.HMPREF9192_1034	7.4e-31	139.4	Bacilli													Bacteria	1V0E0@1239,2EXVW@1,33R50@2,4HBMI@91061	NA|NA|NA	S	Signal peptide protein, YSIRK family
AHPHCOMF_00388	264199.stu1384	1.6e-58	231.9	Bacilli													Bacteria	1VFMU@1239,2E59Z@1,33028@2,4HQG9@91061	NA|NA|NA		
AHPHCOMF_00389	322159.STER_1339	1.3e-268	931.8	Bacilli	uvrX		2.7.7.7	ko:K02346,ko:K03502,ko:K14161					ko00000,ko01000,ko03400				Bacteria	1TP42@1239,4HA1P@91061,COG0389@1,COG0389@2	NA|NA|NA	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AHPHCOMF_00390	264199.stu1386	1.9e-35	154.8	Bacilli													Bacteria	1VBXK@1239,2CWIF@1,32SZQ@2,4HWJ5@91061	NA|NA|NA		
AHPHCOMF_00391	264199.stu1386	4e-20	104.4	Bacilli													Bacteria	1VBXK@1239,2CWIF@1,32SZQ@2,4HWJ5@91061	NA|NA|NA		
AHPHCOMF_00392	1166016.W5S_0451	3.3e-24	118.2	Pectobacterium													Bacteria	1MTFE@122277,1Q7JG@1224,1TCUQ@1236,COG0318@1,COG0318@2	NA|NA|NA	IQ	PFAM AMP-dependent synthetase and ligase
AHPHCOMF_00393	1041138.KB890229_gene5918	2.7e-26	125.2	Rhizobiaceae													Bacteria	1NU19@1224,2UNVU@28211,4BBY9@82115,COG0318@1,COG0318@2	NA|NA|NA	IQ	PFAM AMP-dependent synthetase and ligase
AHPHCOMF_00394	264199.stu1389	5.8e-109	400.2	Bacilli	MA20_06410												Bacteria	1TRUX@1239,4HFB2@91061,COG1280@1,COG1280@2	NA|NA|NA	E	LysE type translocator
AHPHCOMF_00395	904306.HMPREF9192_0265	5.6e-08	62.0	Bacteria													Bacteria	COG3464@1,COG3464@2	NA|NA|NA		
AHPHCOMF_00396	264199.stu1386	2.7e-09	68.2	Bacilli													Bacteria	1VBXK@1239,2CWIF@1,32SZQ@2,4HWJ5@91061	NA|NA|NA		
AHPHCOMF_00397	322159.STER_1346	0.0	1414.1	Bacilli													Bacteria	1VATJ@1239,4HG1M@91061,COG1216@1,COG1216@2,COG1442@1,COG1442@2	NA|NA|NA	M	family 8
AHPHCOMF_00400	322159.STER_1347	1.5e-162	578.9	Bacilli	hrtB			ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	1VRMK@1239,4HTA7@91061,COG0577@1,COG0577@2	NA|NA|NA	V	MacB-like periplasmic core domain
AHPHCOMF_00401	322159.STER_1348	3.1e-116	424.5	Bacilli	devA		3.6.3.25	ko:K02003,ko:K06020,ko:K09810	ko02010,map02010	M00255,M00258			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125			Bacteria	1TQP5@1239,4HBXK@91061,COG1136@1,COG1136@2	NA|NA|NA	V	abc transporter atp-binding protein
AHPHCOMF_00402	322159.STER_1352	1.1e-151	542.7	Bacilli				ko:K03327,ko:K18908		M00705			ko00000,ko00002,ko01504,ko02000	2.A.66.1,2.A.66.1.13			Bacteria	1V3MS@1239,4HI19@91061,COG0534@1,COG0534@2	NA|NA|NA	V	MatE
AHPHCOMF_00404	435842.HMPREF0848_00444	1.5e-109	402.1	Bacilli				ko:K07011,ko:K22227					ko00000				Bacteria	1TR52@1239,4HAY2@91061,COG0535@1,COG0535@2	NA|NA|NA	C	Fe-S oxidoreductases
AHPHCOMF_00405	585203.SMSK564_1565	1.2e-176	625.9	Bacilli													Bacteria	1VUFN@1239,4HVXJ@91061,COG0477@1,COG2814@2	NA|NA|NA	EGP	Major Facilitator Superfamily
AHPHCOMF_00406	322159.STER_1356	5.5e-258	896.3	Bacteria													Bacteria	COG0535@1,COG0535@2	NA|NA|NA	I	radical SAM domain protein
AHPHCOMF_00408	322159.STER_1358	6.5e-159	566.6	Bacilli	Z012_04635												Bacteria	1UZI0@1239,4HC2C@91061,COG1396@1,COG1396@2	NA|NA|NA	K	Transcriptional activator, Rgg GadR MutR family
AHPHCOMF_00409	322159.STER_1359	1.4e-150	538.9	Firmicutes				ko:K07497					ko00000				Bacteria	1TQQY@1239,COG2801@1,COG2801@2	NA|NA|NA	L	Integrase core domain protein
AHPHCOMF_00410	322159.STER_1360	1.8e-87	328.6	Bacteria				ko:K07483					ko00000				Bacteria	COG2963@1,COG2963@2	NA|NA|NA	L	transposase activity
AHPHCOMF_00412	1035187.HMPREF9959_0071	2.8e-85	321.2	Streptococcus mitis													Bacteria	1U48F@1239,2DKA2@1,2TNQ0@28037,30904@2,4IDZK@91061	NA|NA|NA		
AHPHCOMF_00413	264199.stu1394	0.0	1468.4	Bacilli	sbcC			ko:K03546					ko00000,ko03400				Bacteria	1TPCS@1239,4H9Q3@91061,COG0419@1,COG0419@2	NA|NA|NA	L	ATPase involved in DNA repair
AHPHCOMF_00414	264199.stu1395	2e-230	804.7	Bacilli	sbcD			ko:K03547					ko00000,ko03400				Bacteria	1TQY6@1239,4HAKB@91061,COG0420@1,COG0420@2	NA|NA|NA	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
AHPHCOMF_00415	264199.stu1397	0.0	2126.3	Bacilli	lacL		3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100		R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000				Bacteria	1TPDC@1239,4HANW@91061,COG3250@1,COG3250@2	NA|NA|NA	G	-beta-galactosidase
AHPHCOMF_00416	322159.STER_1367	0.0	1219.9	Bacilli	lacS	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K03292,ko:K11104,ko:K16209					ko00000,ko02000	2.A.2,2.A.2.1,2.A.2.2			Bacteria	1TRA5@1239,4HCDS@91061,COG2190@1,COG2190@2,COG2211@1,COG2211@2	NA|NA|NA	G	transporter
AHPHCOMF_00417	264199.stu1399	2.6e-202	711.1	Bacilli	galM		5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000				Bacteria	1V5UK@1239,4HTRY@91061,COG2017@1,COG2017@2	NA|NA|NA	G	Catalyzes the interconversion of alpha and beta anomers of maltose
AHPHCOMF_00418	322159.STER_1369	6.6e-195	686.4	Bacilli	galE		5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQ7N@1239,4H9U5@91061,COG1087@1,COG1087@2	NA|NA|NA	M	Belongs to the NAD(P)-dependent epimerase dehydratase family
AHPHCOMF_00419	322159.STER_1370	8e-290	1002.3	Bacilli	galT		2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPBN@1239,4HAYJ@91061,COG4468@1,COG4468@2	NA|NA|NA	G	UDPglucose--hexose-1-phosphate uridylyltransferase
AHPHCOMF_00420	264199.stu1402	1.8e-220	771.5	Bacilli	galK	GO:0005975,GO:0005996,GO:0006012,GO:0008150,GO:0008152,GO:0019318,GO:0044238,GO:0044281,GO:0071704	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1TPD0@1239,4HARP@91061,COG0153@1,COG0153@2	NA|NA|NA	G	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AHPHCOMF_00421	264199.stu1403	2.3e-184	651.4	Bacilli	galR			ko:K02529					ko00000,ko03000				Bacteria	1TPZJ@1239,4HC9Z@91061,COG1609@1,COG1609@2	NA|NA|NA	K	Transcriptional regulator
AHPHCOMF_00422	264199.stu0038	2.7e-08	63.2	Firmicutes				ko:K07497					ko00000				Bacteria	1TQQY@1239,COG2801@1,COG2801@2	NA|NA|NA	L	Integrase core domain protein
AHPHCOMF_00423	264199.stu1405	1.2e-25	121.7	Bacteria				ko:K07497					ko00000				Bacteria	COG2801@1,COG2801@2	NA|NA|NA	L	transposition
AHPHCOMF_00424	904306.HMPREF9192_1001	3.5e-228	797.3	Bacilli	zmpB	GO:0005575,GO:0005618,GO:0005623,GO:0009986,GO:0016020,GO:0030312,GO:0044464,GO:0071944		ko:K08643					ko00000,ko01000,ko01002				Bacteria	1UJ29@1239,4IT10@91061,COG3064@1,COG3064@2	NA|NA|NA	M	M26 IgA1-specific Metallo-endopeptidase C-terminal region
AHPHCOMF_00425	264199.stu1407	6.7e-17	92.4	Bacilli	rtxA	GO:0000166,GO:0000287,GO:0000822,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005576,GO:0006464,GO:0006508,GO:0006807,GO:0006996,GO:0007010,GO:0007015,GO:0008144,GO:0008150,GO:0008152,GO:0008154,GO:0008233,GO:0008234,GO:0009405,GO:0009987,GO:0010467,GO:0016043,GO:0016485,GO:0016540,GO:0016787,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018149,GO:0018153,GO:0018193,GO:0018199,GO:0018205,GO:0018262,GO:0018995,GO:0019538,GO:0019835,GO:0019836,GO:0020002,GO:0022411,GO:0030029,GO:0030036,GO:0030042,GO:0030554,GO:0031640,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0033643,GO:0033644,GO:0035639,GO:0035821,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043178,GO:0043412,GO:0043624,GO:0043657,GO:0043933,GO:0044003,GO:0044004,GO:0044179,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044279,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046872,GO:0051261,GO:0051604,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0097435,GO:0140096,GO:1901265,GO:1901363,GO:1901564		ko:K10953	ko05110,map05110				ko00000,ko00001,ko02042				Bacteria	1UJ29@1239,4IT10@91061,COG3064@1,COG3064@2	NA|NA|NA	M	M26 IgA1-specific Metallo-endopeptidase C-terminal region
AHPHCOMF_00426	904306.HMPREF9192_0999	2.5e-101	374.8	Bacilli				ko:K06147					ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21			Bacteria	1TP0B@1239,4HA3S@91061,COG1132@1,COG1132@2	NA|NA|NA	V	abc transporter atp-binding protein
AHPHCOMF_00427	904306.HMPREF9192_0998	4.3e-40	170.2	Bacilli				ko:K06147,ko:K06148					ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21			Bacteria	1TP0B@1239,4H9SC@91061,COG1132@1,COG1132@2	NA|NA|NA	V	abc transporter atp-binding protein
AHPHCOMF_00428	322159.STER_1379	0.0	1509.2	Bacilli	gshF		6.3.2.2,6.3.2.29,6.3.2.30,6.3.2.4	ko:K01919,ko:K01921,ko:K03802,ko:K16786,ko:K16787	ko00270,ko00473,ko00480,ko00550,ko01100,ko01502,ko02010,map00270,map00473,map00480,map00550,map01100,map01502,map02010	M00118,M00582	R00894,R01150,R10993	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35			Bacteria	1TPGX@1239,4HAMJ@91061,COG1181@1,COG1181@2,COG2918@1,COG2918@2	NA|NA|NA	H	Belongs to the glutamate--cysteine ligase type 1 family
AHPHCOMF_00429	264199.stu1414	6.4e-62	243.4	Firmicutes													Bacteria	1TQ93@1239,COG3464@1,COG3464@2	NA|NA|NA	L	Transposase
AHPHCOMF_00430	904306.HMPREF9192_0969	7e-150	536.6	Bacilli	pulA		3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110		R02111		ko00000,ko00001,ko01000		CBM48,GH13		Bacteria	1TP3M@1239,4HBP5@91061,COG1523@1,COG1523@2	NA|NA|NA	G	belongs to the glycosyl hydrolase 13 family
AHPHCOMF_00431	904306.HMPREF9192_0969	1.8e-33	147.9	Bacilli	pulA		3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110		R02111		ko00000,ko00001,ko01000		CBM48,GH13		Bacteria	1TP3M@1239,4HBP5@91061,COG1523@1,COG1523@2	NA|NA|NA	G	belongs to the glycosyl hydrolase 13 family
AHPHCOMF_00432	904306.HMPREF9192_0969	1.7e-120	438.7	Bacilli	pulA		3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110		R02111		ko00000,ko00001,ko01000		CBM48,GH13		Bacteria	1TP3M@1239,4HBP5@91061,COG1523@1,COG1523@2	NA|NA|NA	G	belongs to the glycosyl hydrolase 13 family
AHPHCOMF_00433	264199.stu1416	0.0	1442.9	Bacilli	ftsK	GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141		ko:K03466					ko00000,ko03036	3.A.12			Bacteria	1TPJR@1239,4H9WA@91061,COG1674@1,COG1674@2	NA|NA|NA	D	Belongs to the FtsK SpoIIIE SftA family
AHPHCOMF_00434	264199.stu1417	5.9e-188	663.3	Bacilli	trxB1		1.18.1.2,1.19.1.1	ko:K21567					ko00000,ko01000				Bacteria	1TRPN@1239,4H9V7@91061,COG0492@1,COG0492@2	NA|NA|NA	C	Ferredoxin--NADP reductase
AHPHCOMF_00435	264199.stu1418	1.4e-135	488.8	Bacilli	trmD	GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228,4.6.1.12	ko:K00554,ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R00597,R05637	RC00002,RC00003,RC00334,RC01440	ko00000,ko00001,ko00002,ko01000,ko03016				Bacteria	1TPBV@1239,4HBFV@91061,COG0336@1,COG0336@2	NA|NA|NA	J	Belongs to the RNA methyltransferase TrmD family
AHPHCOMF_00436	264199.stu1419	5.8e-94	350.1	Bacilli	rimM	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360		ko:K02860					ko00000,ko03009				Bacteria	1V6HD@1239,4HH3H@91061,COG0806@1,COG0806@2	NA|NA|NA	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AHPHCOMF_00439	322159.STER_1387	2.2e-114	418.3	Bacilli	vraR			ko:K07694,ko:K11618	ko02020,map02020	M00480,M00481,M00754			ko00000,ko00001,ko00002,ko02022				Bacteria	1TQ1U@1239,4HA4B@91061,COG2197@1,COG2197@2	NA|NA|NA	K	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AHPHCOMF_00440	264199.stu1421	5.8e-175	620.2	Bacilli	vraS		2.7.13.3	ko:K07673,ko:K07681,ko:K11617	ko02020,map02020	M00471,M00480,M00481,M00754			ko00000,ko00001,ko00002,ko01000,ko01001,ko02022				Bacteria	1TPDG@1239,4HC7E@91061,COG4585@1,COG4585@2	NA|NA|NA	T	Histidine kinase
AHPHCOMF_00441	264199.stu1422	3.7e-120	437.6	Bacteria	yvqF			ko:K11622	ko02020,map02020				ko00000,ko00001				Bacteria	COG4758@1,COG4758@2	NA|NA|NA	KT	membrane
AHPHCOMF_00442	264199.stu1425	0.0	1101.3	Bacilli	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K12132					ko00000,ko01000,ko01001				Bacteria	1TP3F@1239,4H9KD@91061,COG0515@1,COG0515@2,COG2815@1,COG2815@2	NA|NA|NA	KLT	serine threonine protein kinase
AHPHCOMF_00443	264199.stu1426	2e-132	478.4	Bacilli	stp		3.1.3.16	ko:K20074					ko00000,ko01000,ko01009				Bacteria	1V6K5@1239,4HCDR@91061,COG0631@1,COG0631@2	NA|NA|NA	T	phosphatase
AHPHCOMF_00444	264199.stu1427	4.4e-247	860.1	Bacilli	sun	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500					ko00000,ko01000,ko03009				Bacteria	1TP3N@1239,4HBQ6@91061,COG0144@1,COG0144@2,COG0781@1,COG0781@2	NA|NA|NA	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AHPHCOMF_00445	264199.stu1428	2.5e-172	611.3	Bacilli	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970		R03940	RC00026,RC00165	ko00000,ko00001,ko01000			iSB619.SA_RS06010	Bacteria	1TQ32@1239,4HART@91061,COG0223@1,COG0223@2	NA|NA|NA	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AHPHCOMF_00446	264199.stu1429	0.0	1580.8	Bacilli	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576		ko:K04066	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1TNYB@1239,4H9WW@91061,COG1198@1,COG1198@2	NA|NA|NA	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AHPHCOMF_00447	264199.stu1430	2.7e-46	191.0	Bacteria	rpoZ	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400				Bacteria	COG1758@1,COG1758@2	NA|NA|NA	K	DNA-directed 5'-3' RNA polymerase activity
AHPHCOMF_00448	264199.stu1431	2e-112	411.8	Bacilli	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000			iYO844.BSU15680	Bacteria	1TP0M@1239,4HAYW@91061,COG0194@1,COG0194@2	NA|NA|NA	F	Essential for recycling GMP and indirectly, cGMP
AHPHCOMF_00449	264199.stu1432	6.7e-214	750.0	Bacilli	ftsY			ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7			Bacteria	1TPRI@1239,4HA6A@91061,COG0552@1,COG0552@2	NA|NA|NA	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AHPHCOMF_00450	322159.STER_1400	5.3e-150	537.0	Bacilli	XK27_02985												Bacteria	1TR2E@1239,4HGA9@91061,COG0561@1,COG0561@2	NA|NA|NA	S	overlaps another CDS with the same product name
AHPHCOMF_00451	322159.STER_1401	8.2e-148	529.6	Bacilli	supH												Bacteria	1V2JE@1239,4IPK2@91061,COG0561@1,COG0561@2	NA|NA|NA	S	overlaps another CDS with the same product name
AHPHCOMF_00452	322159.STER_1402	8.6e-63	246.1	Bacilli	yvoA_1			ko:K07979					ko00000,ko03000				Bacteria	1VFD0@1239,4HNIT@91061,COG1725@1,COG1725@2	NA|NA|NA	K	Transcriptional
AHPHCOMF_00453	264199.stu1436	4.9e-120	437.2	Bacilli	skfE			ko:K01990		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1TPUP@1239,4HGHM@91061,COG1131@1,COG1131@2	NA|NA|NA	V	abc transporter atp-binding protein
AHPHCOMF_00454	322159.STER_1404	5.6e-133	480.3	Bacteria				ko:K01990		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	COG1131@1,COG1131@2	NA|NA|NA	V	ATPase activity
AHPHCOMF_00455	264199.stu1438	3.6e-171	607.4	Bacilli	oppF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1V36J@1239,4HCM4@91061,COG4608@1,COG4608@2	NA|NA|NA	P	Belongs to the ABC transporter superfamily
AHPHCOMF_00456	264199.stu1439	6.4e-204	716.5	Bacilli	oppD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1TP6E@1239,4H9MR@91061,COG0444@1,COG0444@2	NA|NA|NA	P	Belongs to the ABC transporter superfamily
AHPHCOMF_00457	264199.stu1440	2.4e-167	594.7	Bacilli	amiD			ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1TP4R@1239,4HE8S@91061,COG1173@1,COG1173@2	NA|NA|NA	P	ABC transporter (Permease
AHPHCOMF_00458	904306.HMPREF9192_0942	1.1e-270	938.7	Bacilli	amiC	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085		ko:K02033,ko:K13894,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00349,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.21,3.A.1.5.24,3.A.1.5.25			Bacteria	1UY5U@1239,4HEZK@91061,COG0601@1,COG0601@2	NA|NA|NA	P	ABC transporter (Permease
AHPHCOMF_00459	264199.stu1445	0.0	1253.0	Bacilli	amiA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1TQVS@1239,4HCCB@91061,COG4166@1,COG4166@2	NA|NA|NA	E	ABC transporter, substrate-binding protein, family 5
AHPHCOMF_00460	1046629.Ssal_00627	1.2e-24	118.2	Bacilli	oppF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1V36J@1239,4HCM4@91061,COG4608@1,COG4608@2	NA|NA|NA	P	Belongs to the ABC transporter superfamily
AHPHCOMF_00461	264199.stu1447	3.5e-24	117.1	Bacilli	oppF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1V36J@1239,4HCM4@91061,COG4608@1,COG4608@2	NA|NA|NA	P	Belongs to the ABC transporter superfamily
AHPHCOMF_00462	525379.HMPREF0819_1242	8.9e-40	169.1	Bacilli	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575		ko:K03424					ko00000,ko01000				Bacteria	1TNY1@1239,4HA74@91061,COG0084@1,COG0084@2	NA|NA|NA	L	Hydrolase, tatd
AHPHCOMF_00463	322159.STER_1416	6.7e-218	763.1	Bacilli	oxlT			ko:K08177					ko00000,ko02000	2.A.1.11			Bacteria	1TPR9@1239,4HB93@91061,COG2223@1,COG2223@2	NA|NA|NA	P	COG0477 Permeases of the major facilitator superfamily
AHPHCOMF_00464	322159.STER_1417	2.1e-85	321.6	Firmicutes				ko:K07497					ko00000				Bacteria	1TQQY@1239,COG2801@1,COG2801@2	NA|NA|NA	L	Integrase core domain protein
AHPHCOMF_00465	322159.STER_0016	1.9e-78	298.5	Firmicutes				ko:K07483					ko00000				Bacteria	1W68S@1239,COG2963@1,COG2963@2	NA|NA|NA	L	Transposase
AHPHCOMF_00466	264199.stu1455	3.1e-181	641.0	Bacilli	pta		2.3.1.8,3.6.3.21	ko:K00625,ko:K02028,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00236,M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3		iSB619.SA_RS03155	Bacteria	1TPQ0@1239,4H9VH@91061,COG0280@1,COG0280@2	NA|NA|NA	C	phosphate acetyltransferase
AHPHCOMF_00467	264199.stu1456	8.3e-173	612.8	Bacilli	rluD	GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180					ko00000,ko01000,ko03009,ko03016			iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432	Bacteria	1TS1T@1239,4HBRY@91061,COG0564@1,COG0564@2	NA|NA|NA	J	Responsible for synthesis of pseudouridine from uracil
AHPHCOMF_00468	264199.stu1457	5.4e-150	537.0	Bacilli	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100		R00104	RC00002,RC00078	ko00000,ko00001,ko01000			iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895	Bacteria	1TRB3@1239,4HB08@91061,COG0061@1,COG0061@2	NA|NA|NA	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AHPHCOMF_00469	322159.STER_1423	5.5e-121	440.3	Bacilli	yjbM		2.7.6.5	ko:K07816	ko00230,map00230		R00429	RC00002,RC00078	ko00000,ko00001,ko01000				Bacteria	1TQ2F@1239,4HA3Q@91061,COG2357@1,COG2357@2	NA|NA|NA	S	Gtp pyrophosphokinase
AHPHCOMF_00470	264199.stu1458	1.5e-103	382.1	Bacilli	yjbK												Bacteria	1VA56@1239,4HMNE@91061,COG4116@1,COG4116@2	NA|NA|NA	S	Adenylate cyclase
AHPHCOMF_00471	322159.STER_1425	1.2e-177	629.0	Bacilli	prs		2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_2848	Bacteria	1TQ4I@1239,4HDRN@91061,COG0462@1,COG0462@2	NA|NA|NA	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AHPHCOMF_00472	264199.stu1461	1.2e-205	722.2	Bacilli	iscS		2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122		R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029				Bacteria	1TP21@1239,4HA6H@91061,COG1104@1,COG1104@2	NA|NA|NA	E	Cysteine desulfurase
AHPHCOMF_00473	322159.STER_1427	3.1e-59	234.2	Bacilli	XK27_04120												Bacteria	1VDSF@1239,2DHWG@1,32U9W@2,4HP9N@91061	NA|NA|NA	S	Putative amino acid metabolism
AHPHCOMF_00474	904306.HMPREF9192_0932	1.1e-116	426.0	Bacilli	rex			ko:K01926					ko00000,ko03000				Bacteria	1TSMR@1239,4HB7Q@91061,COG2344@1,COG2344@2	NA|NA|NA	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AHPHCOMF_00475	264199.stu1464	4.8e-128	463.8	Bacilli	puuD			ko:K07010					ko00000,ko01002				Bacteria	1V1KC@1239,4HI59@91061,COG2071@1,COG2071@2	NA|NA|NA	T	peptidase C26
AHPHCOMF_00476	322159.STER_1430	1.2e-115	422.5	Bacilli	radC			ko:K03630					ko00000				Bacteria	1TQ3K@1239,4HB1W@91061,COG2003@1,COG2003@2	NA|NA|NA	E	Belongs to the UPF0758 family
AHPHCOMF_00477	322159.STER_1431	1.7e-268	931.4	Bacteria													Bacteria	COG4713@1,COG4713@2	NA|NA|NA	M	Psort location CytoplasmicMembrane, score
AHPHCOMF_00478	322159.STER_1432	0.0	1194.9	Bacilli	rgpF			ko:K07272					ko00000,ko01000,ko01003,ko01005				Bacteria	1V95X@1239,4HIXP@91061,COG3754@1,COG3754@2	NA|NA|NA	M	Rhamnan synthesis protein F
AHPHCOMF_00479	322159.STER_1433	4.5e-305	1053.1	Bacteria				ko:K00754					ko00000,ko01000		GT4		Bacteria	COG0438@1,COG0438@2	NA|NA|NA	M	transferase activity, transferring glycosyl groups
AHPHCOMF_00480	322159.STER_1434	6.4e-229	799.7	Bacilli	rgpD		3.6.3.38	ko:K01990,ko:K09689,ko:K09691	ko02010,map02010	M00249,M00250,M00254			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.101,3.A.1.103			Bacteria	1TQKK@1239,4HC6N@91061,COG1134@1,COG1134@2	NA|NA|NA	P	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
AHPHCOMF_00481	322159.STER_1435	1.8e-142	511.9	Bacilli	rgpC			ko:K01992		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1V1J2@1239,4HI7C@91061,COG1682@1,COG1682@2	NA|NA|NA	GM	Transport permease protein
AHPHCOMF_00482	322159.STER_1436	6.4e-176	623.2	Bacilli	rgpB			ko:K12997					ko00000,ko01000,ko01003,ko01005		GT2		Bacteria	1V7IQ@1239,4HK7R@91061,COG0463@1,COG0463@2	NA|NA|NA	M	Glycosyltransferase, group 2 family protein
AHPHCOMF_00483	322159.STER_1437	2.3e-228	797.7	Bacilli	rgpA			ko:K12996					ko00000,ko01000,ko01003,ko01005		GT4		Bacteria	1V7K7@1239,4HA9A@91061,COG0438@1,COG0438@2	NA|NA|NA	M	Domain of unknown function (DUF1972)
AHPHCOMF_00484	322159.STER_1438	2.4e-152	544.7	Firmicutes			2.4.1.60	ko:K07011,ko:K13005					ko00000,ko01000,ko01003,ko01005				Bacteria	1UI19@1239,COG1216@1,COG1216@2	NA|NA|NA	S	Glycosyltransferase group 2 family protein
AHPHCOMF_00485	1046629.Ssal_00599	4.6e-42	177.2	Firmicutes				ko:K09153					ko00000				Bacteria	1VPQZ@1239,2EVMS@1,33P1S@2	NA|NA|NA	S	Uncharacterized conserved protein (DUF2304)
AHPHCOMF_00486	322159.STER_1440	6.9e-130	469.9	Bacilli	arnC			ko:K00786					ko00000,ko01000				Bacteria	1UHQZ@1239,4IS6R@91061,COG1215@1,COG1215@2	NA|NA|NA	M	group 2 family protein
AHPHCOMF_00487	322159.STER_1441	9.5e-183	646.0	Bacilli	cpsIaJ												Bacteria	1V3XP@1239,4HQNP@91061,COG1216@1,COG1216@2	NA|NA|NA	S	Glycosyltransferase like family 2
AHPHCOMF_00488	322159.STER_1442	1e-184	652.5	Firmicutes													Bacteria	1UJE4@1239,COG1216@1,COG1216@2	NA|NA|NA	S	Glycosyltransferase like family 2
AHPHCOMF_00489	322159.STER_1443	9.4e-223	779.2	Bacilli	amrA												Bacteria	1V1RP@1239,4IR8D@91061,COG2244@1,COG2244@2	NA|NA|NA	S	membrane protein involved in the export of O-antigen and teichoic acid
AHPHCOMF_00490	322159.STER_1444	2.6e-160	571.2	Bacilli	rfbD		1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP71@1239,4HBXF@91061,COG1091@1,COG1091@2	NA|NA|NA	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
AHPHCOMF_00491	322159.STER_1445	2e-236	824.7	Bacilli													Bacteria	1VTTT@1239,4HW49@91061,COG4713@1,COG4713@2	NA|NA|NA	S	Predicted membrane protein (DUF2142)
AHPHCOMF_00492	322159.STER_1446	1.7e-173	615.1	Bacilli	yfdH			ko:K12999,ko:K20534					ko00000,ko01000,ko01003,ko01005,ko02000	4.D.2.1.9	GT2		Bacteria	1TPR3@1239,4HC2Z@91061,COG0463@1,COG0463@2	NA|NA|NA	M	COG0463, glycosyltransferases involved in cell wall biogenesis
AHPHCOMF_00493	264199.stu1487	3.4e-55	220.7	Bacilli	yitW			ko:K02612	ko00360,ko01120,map00360,map01120		R09838	RC02690	ko00000,ko00001				Bacteria	1V9YV@1239,4HKC6@91061,COG2151@1,COG2151@2	NA|NA|NA	K	metal-sulfur cluster biosynthetic enzyme
AHPHCOMF_00494	322159.STER_1448	1.1e-201	709.1	Bacilli	sigA	GO:0000988,GO:0000990,GO:0001098,GO:0001101,GO:0001108,GO:0001666,GO:0002791,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0016020,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032879,GO:0032880,GO:0036293,GO:0040007,GO:0042221,GO:0043175,GO:0043254,GO:0044087,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051173,GO:0051223,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070063,GO:0070201,GO:0070482,GO:0071944,GO:0080090,GO:0090087,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:1903530,GO:2000112,GO:2000142,GO:2001141		ko:K03086,ko:K03087	ko02026,ko05111,map02026,map05111				ko00000,ko00001,ko03021				Bacteria	1TPD6@1239,4HB1H@91061,COG0568@1,COG0568@2	NA|NA|NA	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
AHPHCOMF_00495	322159.STER_1449	0.0	1179.1	Bacilli	dnaG			ko:K02316	ko03030,map03030				ko00000,ko00001,ko01000,ko03032				Bacteria	1TQ0X@1239,4HAG2@91061,COG0358@1,COG0358@2	NA|NA|NA	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
AHPHCOMF_00496	322159.STER_1451	5.5e-20	102.8	Firmicutes	rpsU	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02970	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1VEHU@1239,COG0828@1,COG0828@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bS21 family
AHPHCOMF_00497	322159.STER_1452	1.1e-136	492.7	Bacilli	gltS			ko:K02030,ko:K17073,ko:K17074	ko02010,map02010	M00236,M00589			ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.20			Bacteria	1TT16@1239,4HD16@91061,COG0834@1,COG0834@2	NA|NA|NA	ET	Belongs to the bacterial solute-binding protein 3 family
AHPHCOMF_00498	322159.STER_1453	2.1e-202	711.4	Bacilli	arcT		2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230		R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007				Bacteria	1TQPD@1239,4HE7P@91061,COG0436@1,COG0436@2	NA|NA|NA	E	Aminotransferase
AHPHCOMF_00499	322159.STER_1454	9.4e-136	489.6	Bacilli				ko:K02030,ko:K17073,ko:K17074	ko02010,map02010	M00236,M00589			ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.20			Bacteria	1TT16@1239,4HJ2R@91061,COG0834@1,COG0834@2	NA|NA|NA	ET	ABC transporter
AHPHCOMF_00500	264199.stu1495	3.7e-143	514.2	Firmicutes				ko:K02030,ko:K17073,ko:K17074	ko02010,map02010	M00236,M00589			ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.20			Bacteria	1TT16@1239,COG0834@1,COG0834@2	NA|NA|NA	ET	Belongs to the bacterial solute-binding protein 3 family
AHPHCOMF_00501	322159.STER_1456	2.9e-84	317.8	Firmicutes	mutT		3.6.1.55	ko:K03574					ko00000,ko01000,ko03400				Bacteria	1V3MM@1239,COG1051@1,COG1051@2	NA|NA|NA	F	Nudix family
AHPHCOMF_00502	264199.stu1497	0.0	1287.7	Bacilli	uvrB			ko:K03702,ko:K08999	ko03420,map03420				ko00000,ko00001,ko03400				Bacteria	1TPKB@1239,4HB81@91061,COG0556@1,COG0556@2	NA|NA|NA	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
AHPHCOMF_00504	904306.HMPREF9192_0897	2e-78	298.5	Bacilli				ko:K07052					ko00000				Bacteria	1VA8S@1239,4IQWI@91061,COG1266@1,COG1266@2	NA|NA|NA	S	CAAX amino terminal protease family protein
AHPHCOMF_00505	904306.HMPREF9192_0897	7.6e-32	142.9	Bacilli				ko:K07052					ko00000				Bacteria	1VA8S@1239,4IQWI@91061,COG1266@1,COG1266@2	NA|NA|NA	S	CAAX amino terminal protease family protein
AHPHCOMF_00506	264199.stu1501	0.0	1365.9	Bacilli	glnP			ko:K02029,ko:K02030,ko:K10040,ko:K17073,ko:K17074	ko02010,map02010	M00228,M00236,M00589			ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.20			Bacteria	1TQUG@1239,4HAJ5@91061,COG0765@1,COG0765@2,COG0834@1,COG0834@2	NA|NA|NA	P	ABC-type amino acid transport signal transduction systems periplasmic component domain
AHPHCOMF_00507	264199.stu1502	6e-137	493.4	Bacilli	glnQ		3.6.3.21	ko:K02028,ko:K10038	ko02010,map02010	M00227,M00236			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.2			Bacteria	1TNYD@1239,4H9WY@91061,COG1126@1,COG1126@2	NA|NA|NA	E	abc transporter atp-binding protein
AHPHCOMF_00508	1214217.ALNF01000018_gene931	1.1e-16	92.0	Streptococcus suis	XK27_00735												Bacteria	1U94Q@1239,1WTRS@1307,29R2M@1,30C3R@2,4IJ5T@91061	NA|NA|NA		
AHPHCOMF_00509	264199.stu1504	1.4e-248	865.1	Bacilli	obg	GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043021,GO:0043022,GO:0043167,GO:0043168,GO:0043934,GO:0044424,GO:0044464,GO:0044877,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363		ko:K03979					ko00000,ko01000,ko03009				Bacteria	1TPX7@1239,4H9P8@91061,COG0536@1,COG0536@2	NA|NA|NA	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AHPHCOMF_00511	322159.STER_1466	6.2e-134	483.4	Bacilli	rsuA	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183					ko00000,ko01000,ko03009				Bacteria	1TQZ2@1239,4H9VU@91061,COG1187@1,COG1187@2	NA|NA|NA	J	Belongs to the pseudouridine synthase RsuA family
AHPHCOMF_00514	264199.stu1516	5.5e-65	253.4	Bacilli	paaI			ko:K02614	ko00360,map00360		R09840	RC00004,RC00014	ko00000,ko00001,ko01000				Bacteria	1VN0K@1239,4HM66@91061,COG2050@1,COG2050@2	NA|NA|NA	Q	protein possibly involved in aromatic compounds catabolism
AHPHCOMF_00515	322159.STER_1470	6.6e-30	136.0	Bacteria	ycaO			ko:K06889,ko:K07397,ko:K09136					ko00000,ko03009				Bacteria	COG1765@1,COG1765@2	NA|NA|NA	O	OsmC-like protein
AHPHCOMF_00517	322159.STER_1472	1.7e-154	552.0	Firmicutes													Bacteria	1TYSF@1239,COG0697@1,COG0697@2	NA|NA|NA	EG	Permeases of the drug metabolite transporter (DMT) superfamily
AHPHCOMF_00519	322159.STER_1474	5.6e-110	403.7	Bacilli	csn2			ko:K19137					ko00000,ko02048				Bacteria	1V1IF@1239,298VG@1,2ZVZK@2,4HGGM@91061	NA|NA|NA	S	CRISPR-associated protein (Cas_Csn2)
AHPHCOMF_00520	322159.STER_1475	3.5e-52	210.7	Bacilli	cas2			ko:K09951					ko00000,ko02048				Bacteria	1VEH4@1239,4HNYR@91061,COG3512@1,COG3512@2	NA|NA|NA	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AHPHCOMF_00521	322159.STER_1476	1.5e-163	582.0	Bacilli	cas1			ko:K15342					ko00000,ko02048,ko03400				Bacteria	1TT0J@1239,4HC5E@91061,COG1518@1,COG1518@2	NA|NA|NA	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AHPHCOMF_00522	322159.STER_1477	0.0	2707.2	Bacilli	cas9			ko:K09952					ko00000,ko01000,ko02048				Bacteria	1TPSD@1239,4HE0R@91061,COG3513@1,COG3513@2	NA|NA|NA	L	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
AHPHCOMF_00523	322159.STER_1478	6.7e-116	423.3	Bacilli	serB		3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009				Bacteria	1V9R7@1239,4HTNE@91061,COG0560@1,COG0560@2	NA|NA|NA	E	phosphoserine phosphatase
AHPHCOMF_00524	264199.stu1520	1.6e-297	1028.1	Bacilli	ezrA	GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047		ko:K06286,ko:K07158					ko00000,ko03036				Bacteria	1TQR7@1239,4HA15@91061,COG4477@1,COG4477@2	NA|NA|NA	D	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AHPHCOMF_00525	264199.stu1521	0.0	1276.2	Bacilli	gyrB	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	5.99.1.3	ko:K02470,ko:K02622					ko00000,ko01000,ko02048,ko03032,ko03036,ko03400				Bacteria	1TQ0R@1239,4H9Y6@91061,COG0187@1,COG0187@2	NA|NA|NA	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AHPHCOMF_00526	264199.stu1522	2.6e-109	401.4	Bacilli			3.1.3.18	ko:K01091,ko:K07025	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130		R01334	RC00017	ko00000,ko00001,ko01000				Bacteria	1V421@1239,4HHYH@91061,COG0546@1,COG0546@2	NA|NA|NA	S	IA, variant 1
AHPHCOMF_00527	322159.STER_1482	2.2e-117	428.3	Bacilli	lrgB												Bacteria	1TRGN@1239,4HF0M@91061,COG1346@1,COG1346@2	NA|NA|NA	M	effector of murein hydrolase
AHPHCOMF_00528	322159.STER_1483	7.7e-56	223.0	Firmicutes	lrgA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K06518					ko00000,ko02000	1.E.14.2			Bacteria	1VEN4@1239,COG1380@1,COG1380@2	NA|NA|NA	S	Effector of murein hydrolase LrgA
AHPHCOMF_00530	264199.stu1525	6.4e-60	236.5	Bacilli	arsC		1.20.4.1	ko:K00537,ko:K16509					ko00000,ko01000				Bacteria	1VA5Q@1239,4HKQQ@91061,COG1393@1,COG1393@2	NA|NA|NA	P	Belongs to the ArsC family
AHPHCOMF_00531	904306.HMPREF9192_0874	6.3e-57	226.5	Bacteria	ogt	GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	2.1.1.63,3.2.2.20	ko:K00567,ko:K01246	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	COG0350@1,COG0350@2	NA|NA|NA	L	methylated-DNA-[protein]-cysteine S-methyltransferase activity
AHPHCOMF_00532	322159.STER_1487	7e-220	769.6	Bacilli	serA		1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1V410@1239,4H9PH@91061,COG0111@1,COG0111@2	NA|NA|NA	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AHPHCOMF_00533	264199.stu1528	1.3e-104	385.6	Bacilli	wecD												Bacteria	1UIW7@1239,4ISU9@91061,COG1247@1,COG1247@2	NA|NA|NA	M	Acetyltransferase (GNAT) domain
AHPHCOMF_00534	322159.STER_1489	1.3e-209	735.3	Bacilli	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	1TP6Y@1239,4HATT@91061,COG1932@1,COG1932@2	NA|NA|NA	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AHPHCOMF_00535	264199.stu1530	5.1e-96	357.1	Bacilli													Bacteria	1TRQ7@1239,4HE30@91061,COG1940@1,COG1940@2	NA|NA|NA	GK	ROK family
AHPHCOMF_00536	264199.stu1532	8.1e-72	276.2	Bacilli	gloA		4.4.1.5	ko:K01759,ko:K15772	ko00620,ko02010,map00620,map02010	M00491	R02530	RC00004,RC00740	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1.16,3.A.1.1.2			Bacteria	1V6K3@1239,4HJ7X@91061,COG0346@1,COG0346@2	NA|NA|NA	E	Lactoylglutathione lyase
AHPHCOMF_00537	264199.stu1533	6.6e-62	243.4	Bacteria	XK27_08050												Bacteria	COG0330@1,COG0330@2	NA|NA|NA	O	stress-induced mitochondrial fusion
AHPHCOMF_00538	1046629.Ssal_00531	9.6e-26	122.1	Bacilli	XK27_08050												Bacteria	1TPXU@1239,4HGRC@91061,COG0330@1,COG0330@2	NA|NA|NA	O	HflC and HflK could regulate a protease
AHPHCOMF_00539	904306.HMPREF9192_0867	1.3e-19	102.1	Bacilli	XK27_08050												Bacteria	1TPXU@1239,4HGRC@91061,COG0330@1,COG0330@2	NA|NA|NA	O	HflC and HflK could regulate a protease
AHPHCOMF_00540	264199.stu1535	2.3e-206	724.5	Bacilli	potD			ko:K11069	ko02010,map02010	M00299			ko00000,ko00001,ko00002,ko02000	3.A.1.11.1		iSB619.SA_RS05395	Bacteria	1TPY1@1239,4HAET@91061,COG0687@1,COG0687@2	NA|NA|NA	P	spermidine putrescine ABC transporter
AHPHCOMF_00541	322159.STER_1494	3e-134	484.6	Bacilli	potC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008519,GO:0015075,GO:0015101,GO:0015203,GO:0015399,GO:0015405,GO:0015417,GO:0015595,GO:0015606,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0015848,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072488,GO:0098533,GO:0098655,GO:0098796,GO:0098797,GO:1902047,GO:1902494,GO:1902495,GO:1903711,GO:1904949,GO:1990351		ko:K11070	ko02010,map02010	M00299			ko00000,ko00001,ko00002,ko02000	3.A.1.11.1		iSBO_1134.SBO_1939	Bacteria	1V0VD@1239,4H9ZC@91061,COG1177@1,COG1177@2	NA|NA|NA	P	ABC-type spermidine putrescine transport system, permease component II
AHPHCOMF_00542	264199.stu1537	3.7e-140	504.2	Bacilli	potB			ko:K11071	ko02010,map02010	M00299			ko00000,ko00001,ko00002,ko02000	3.A.1.11.1			Bacteria	1TQ7Z@1239,4HAYS@91061,COG1176@1,COG1176@2	NA|NA|NA	P	ABC-type spermidine putrescine transport system, permease component I
AHPHCOMF_00543	322159.STER_1496	1.2e-213	748.8	Bacilli	potA		3.6.3.30,3.6.3.31	ko:K02010,ko:K11072	ko02010,map02010	M00190,M00299			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11.1		iSB619.SA_RS05380	Bacteria	1TP2M@1239,4H9MS@91061,COG3842@1,COG3842@2	NA|NA|NA	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
AHPHCOMF_00544	322159.STER_1497	2.3e-170	604.7	Bacilli	murB		1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100		R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011				Bacteria	1TP3W@1239,4HAD8@91061,COG0812@1,COG0812@2	NA|NA|NA	M	cell wall formation
AHPHCOMF_00545	322159.STER_1498	2.9e-87	327.8	Bacilli	folK		2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000				Bacteria	1V6PR@1239,4HIMG@91061,COG0801@1,COG0801@2	NA|NA|NA	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AHPHCOMF_00546	264199.stu1541	1.2e-61	242.3	Bacilli	folB		1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8	ko:K00796,ko:K00950,ko:K01633,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503,R03504,R11037,R11073	RC00002,RC00017,RC00121,RC00721,RC00842,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000				Bacteria	1VA0I@1239,4HKKK@91061,COG1539@1,COG1539@2	NA|NA|NA	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AHPHCOMF_00547	264199.stu1542	6e-298	1029.2	Bacilli	amy		3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973		R02108,R02112,R11262		ko00000,ko00001,ko01000		GH13		Bacteria	1TRKZ@1239,4HC8C@91061,COG0366@1,COG0366@2	NA|NA|NA	G	Belongs to the glycosyl hydrolase 13 family
AHPHCOMF_00548	264199.stu1543	7e-147	526.6	Bacilli	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000			iHN637.CLJU_RS03115	Bacteria	1TPKT@1239,4H9SY@91061,COG0294@1,COG0294@2	NA|NA|NA	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AHPHCOMF_00549	264199.stu1544	1e-99	369.4	Bacilli	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000			iNJ661.Rv3609c	Bacteria	1TRNM@1239,4HAXS@91061,COG0302@1,COG0302@2	NA|NA|NA	F	gtp cyclohydrolase
AHPHCOMF_00550	322159.STER_1503	0.0	1163.7	Bacilli	ydaO	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039											Bacteria	1TQE1@1239,4HAZH@91061,COG0531@1,COG0531@2	NA|NA|NA	E	amino acid
AHPHCOMF_00551	264199.stu1546	2.1e-238	831.2	Bacilli	folC		6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000			iLJ478.TM0166	Bacteria	1TPX5@1239,4HBJM@91061,COG0285@1,COG0285@2	NA|NA|NA	H	Belongs to the folylpolyglutamate synthase family
AHPHCOMF_00552	264199.stu1547	4.1e-37	160.2	Bacteria	ylqC			ko:K06960					ko00000				Bacteria	COG1837@1,COG1837@2	NA|NA|NA	L	Belongs to the UPF0109 family
AHPHCOMF_00553	1046629.Ssal_00517	2.4e-43	181.0	Bacilli	rpsP	GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02959	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011,ko03029				Bacteria	1VA0X@1239,4HKNN@91061,COG0228@1,COG0228@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bS16 family
AHPHCOMF_00554	322159.STER_1507	6.9e-172	609.8	Bacilli	tehB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0010035,GO:0016740,GO:0016741,GO:0032259,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046690,GO:0050896	2.1.1.265	ko:K03647,ko:K16868					ko00000,ko01000				Bacteria	1TSZK@1239,4HJT1@91061,COG0500@1,COG0500@2,COG3615@1,COG3615@2	NA|NA|NA	PQ	tellurite resistance protein tehb
AHPHCOMF_00555	264199.stu1550	1e-156	559.3	Bacilli	xth	GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.11.2	ko:K01142	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	1TPFB@1239,4HAIU@91061,COG0708@1,COG0708@2	NA|NA|NA	L	exodeoxyribonuclease III
AHPHCOMF_00556	322159.STER_1509	2.1e-74	285.0	Firmicutes													Bacteria	1V99E@1239,COG4708@1,COG4708@2	NA|NA|NA	S	QueT transporter
AHPHCOMF_00557	264199.stu1552	4.9e-120	437.2	Bacilli	ribD		1.1.1.193,3.5.4.26	ko:K00082,ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000			iLJ478.TM1828	Bacteria	1UHQR@1239,4IS6G@91061,COG1985@1,COG1985@2	NA|NA|NA	L	Transposase DDE domain
AHPHCOMF_00558	322159.STER_1512	5.7e-186	656.8	Bacilli	yegS	GO:0001727,GO:0003674,GO:0003824,GO:0004143,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0030258,GO:0044237,GO:0044238,GO:0044255,GO:0046834,GO:0071704	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110		R02240	RC00002,RC00017	ko00000,ko00001,ko01000				Bacteria	1TQAU@1239,4H9WD@91061,COG1597@1,COG1597@2	NA|NA|NA	I	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
AHPHCOMF_00559	322159.STER_1513	0.0	1239.9	Bacilli	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430		R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400				Bacteria	1TPQ3@1239,4HA1D@91061,COG0272@1,COG0272@2	NA|NA|NA	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AHPHCOMF_00560	264199.stu1555	3.7e-85	320.9	Bacilli	ccl	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944											Bacteria	1V22G@1239,4HGG2@91061,COG4708@1,COG4708@2	NA|NA|NA	S	cog cog4708
AHPHCOMF_00561	264199.stu1556	2.8e-163	581.3	Bacilli	rbn			ko:K07058					ko00000				Bacteria	1U7HM@1239,4H9MJ@91061,COG1295@1,COG1295@2	NA|NA|NA	E	Belongs to the UPF0761 family
AHPHCOMF_00562	264199.stu1557	1.5e-166	592.0	Bacilli	map	GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605	3.4.11.18	ko:K01265					ko00000,ko01000,ko01002				Bacteria	1TQC1@1239,4H9S9@91061,COG0024@1,COG0024@2	NA|NA|NA	E	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
AHPHCOMF_00563	322159.STER_1517	3.3e-231	807.4	Bacilli	ytoI												Bacteria	1TPU6@1239,4HB62@91061,COG4109@1,COG4109@2	NA|NA|NA	K	transcriptional regulator containing CBS domains
AHPHCOMF_00564	322159.STER_1518	2.4e-98	364.8	Bacilli	XK27_07830		2.3.1.128	ko:K03790					ko00000,ko01000,ko03009				Bacteria	1V576@1239,4HH6U@91061,COG1670@1,COG1670@2	NA|NA|NA	J	Acetyltransferase GNAT Family
AHPHCOMF_00565	264199.stu1560	1e-232	812.4	Bacilli	murA	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100		R00660	RC00350	ko00000,ko00001,ko01000,ko01011			iYO844.BSU37100	Bacteria	1TPAU@1239,4H9KI@91061,COG0766@1,COG0766@2	NA|NA|NA	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AHPHCOMF_00566	264199.stu1561	0.0	1441.4	Bacilli	comEC			ko:K02238		M00429			ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2			Bacteria	1TS9U@1239,4H9M4@91061,COG0658@1,COG0658@2,COG2333@1,COG2333@2	NA|NA|NA	S	Competence protein ComEC
AHPHCOMF_00567	322159.STER_1521	2.2e-96	358.6	Bacilli	comEA			ko:K02237		M00429			ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2			Bacteria	1VA3W@1239,4HKJ1@91061,COG1555@1,COG1555@2	NA|NA|NA	L	COG1555 DNA uptake protein and related DNA-binding proteins
AHPHCOMF_00568	264199.stu1563	1.3e-142	512.3	Bacilli	plsC	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008374,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0042171,GO:0044464,GO:0071617,GO:0071944	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	1U8N2@1239,4HDQR@91061,COG0204@1,COG0204@2	NA|NA|NA	I	Acyltransferase
AHPHCOMF_00569	264199.stu1564	4.4e-73	280.8	Bacteria	nodB3												Bacteria	COG0726@1,COG0726@2	NA|NA|NA	G	polysaccharide deacetylase
AHPHCOMF_00570	435842.HMPREF0848_01183	1.5e-61	241.9	Bacilli	nodB3												Bacteria	1TYRH@1239,4HHQN@91061,COG0726@1,COG0726@2	NA|NA|NA	G	deacetylase
AHPHCOMF_00571	322159.STER_1524	7.1e-141	506.5	Bacilli	yabB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.223	ko:K07461,ko:K15460					ko00000,ko01000,ko03016				Bacteria	1TQ25@1239,4HA8W@91061,COG4123@1,COG4123@2	NA|NA|NA	L	Methyltransferase
AHPHCOMF_00572	264199.stu1567	1e-41	175.6	Bacilli	yazA			ko:K07461					ko00000				Bacteria	1VEZF@1239,4HNHJ@91061,COG2827@1,COG2827@2	NA|NA|NA	L	endonuclease containing a URI domain
AHPHCOMF_00573	264199.stu1568	3.2e-252	877.5	Bacilli	cshA	GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363	3.6.4.13	ko:K05592,ko:K18692	ko03018,map03018				ko00000,ko00001,ko01000,ko03009,ko03019				Bacteria	1TPAP@1239,4HAB3@91061,COG0513@1,COG0513@2	NA|NA|NA	JKL	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
AHPHCOMF_00574	264199.stu1569	3.9e-154	550.8	Bacilli	corA			ko:K03284					ko00000,ko02000	1.A.35.1,1.A.35.3			Bacteria	1TPI8@1239,4HCQ6@91061,COG0598@1,COG0598@2	NA|NA|NA	P	CorA-like protein
AHPHCOMF_00575	322159.STER_1528	1.9e-62	245.0	Bacilli	yjqA												Bacteria	1V77G@1239,3172B@2,4HJ0W@91061,arCOG12631@1	NA|NA|NA	S	Bacterial PH domain
AHPHCOMF_00576	264199.stu1571	7.8e-100	369.8	Bacilli	thiT			ko:K16789					ko00000,ko02000	2.A.88.3			Bacteria	1V6YE@1239,4HIJE@91061,COG3859@1,COG3859@2	NA|NA|NA	S	Thiamine transporter
AHPHCOMF_00577	322159.STER_1530	2.1e-157	561.6	Bacilli	Z012_04635												Bacteria	1UZI0@1239,4HC2C@91061,COG1396@1,COG1396@2	NA|NA|NA	K	Transcriptional activator, Rgg GadR MutR family
AHPHCOMF_00578	322159.STER_1531	6e-175	620.2	Bacilli	yjbB			ko:K08220					ko00000,ko02000	2.A.1.28.1,2.A.1.28.4			Bacteria	1TR4D@1239,4HDCY@91061,COG2211@1,COG2211@2	NA|NA|NA	G	Permeases of the major facilitator superfamily
AHPHCOMF_00579	322159.STER_1532	3.1e-300	1036.9	Bacilli	prfC	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576		ko:K02837,ko:K07133					ko00000,ko03012				Bacteria	1TPYT@1239,4HADS@91061,COG4108@1,COG4108@2	NA|NA|NA	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AHPHCOMF_00580	322159.STER_1533	1.4e-121	442.2	Bacteria	ywaF												Bacteria	COG5522@1,COG5522@2	NA|NA|NA	S	Integral membrane protein (intg_mem_TP0381)
AHPHCOMF_00581	322159.STER_1534	1.5e-258	898.3	Bacilli	murF		6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502		R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011				Bacteria	1VT78@1239,4HACR@91061,COG0770@1,COG0770@2	NA|NA|NA	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
AHPHCOMF_00585	322159.STER_1539	1.1e-155	555.8	Bacilli	cjaA			ko:K02030		M00236			ko00000,ko00002,ko02000	3.A.1.3			Bacteria	1TT11@1239,4HFBQ@91061,COG0834@1,COG0834@2	NA|NA|NA	ET	ABC transporter substrate-binding protein
AHPHCOMF_00586	264199.stu1580	1.4e-136	492.3	Bacilli	glnQ		3.6.3.21	ko:K02028		M00236			ko00000,ko00002,ko01000,ko02000	3.A.1.3			Bacteria	1TNYD@1239,4HDK7@91061,COG1126@1,COG1126@2	NA|NA|NA	E	abc transporter atp-binding protein
AHPHCOMF_00587	322159.STER_1541	1.3e-114	419.1	Bacilli				ko:K02029		M00236			ko00000,ko00002,ko02000	3.A.1.3			Bacteria	1TR7R@1239,4HGVA@91061,COG0765@1,COG0765@2	NA|NA|NA	P	ABC transporter (Permease
AHPHCOMF_00588	322159.STER_1542	1e-114	419.5	Bacilli	papP			ko:K02029		M00236			ko00000,ko00002,ko02000	3.A.1.3			Bacteria	1TRU3@1239,4HGE1@91061,COG0765@1,COG0765@2	NA|NA|NA	P	ABC transporter (Permease
AHPHCOMF_00589	264199.stu1583	6.4e-193	679.9	Bacilli	ddl		6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502		R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011				Bacteria	1TP2Y@1239,4H9KB@91061,COG1181@1,COG1181@2	NA|NA|NA	F	Belongs to the D-alanine--D-alanine ligase family
AHPHCOMF_00590	264199.stu1584	2e-29	134.4	Bacilli	copZ	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0006811,GO:0006812,GO:0006873,GO:0006875,GO:0008150,GO:0009987,GO:0019725,GO:0030001,GO:0030003,GO:0042592,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771	2.7.7.77	ko:K03752,ko:K07213,ko:K08364	ko00790,ko01100,ko04978,map00790,map01100,map04978		R11581		ko00000,ko00001,ko01000,ko02000	1.A.72.1			Bacteria	1VK5F@1239,4HR1Z@91061,COG2608@1,COG2608@2	NA|NA|NA	P	Heavy metal-associated domain protein
AHPHCOMF_00591	322159.STER_1546	0.0	1312.0	Bacilli	copA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016		R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5			Bacteria	1TP5S@1239,4HAI0@91061,COG2217@1,COG2217@2	NA|NA|NA	P	P-type ATPase
AHPHCOMF_00592	322159.STER_1547	2.7e-73	281.2	Bacilli	copY												Bacteria	1VA7Q@1239,4HKGF@91061,COG3682@1,COG3682@2	NA|NA|NA	K	Copper transport repressor, CopY TcrY family
AHPHCOMF_00593	264199.stu1587	2.1e-143	515.0	Bacilli	trpA		4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPXA@1239,4HFQ8@91061,COG0159@1,COG0159@2	NA|NA|NA	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
AHPHCOMF_00594	264199.stu1588	1.1e-228	798.9	Bacilli	trpB	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20,5.3.1.24	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03509	RC00209,RC00210,RC00700,RC00701,RC00945,RC02868	ko00000,ko00001,ko00002,ko01000			iYO844.BSU22640	Bacteria	1TPI3@1239,4H9WC@91061,COG0133@1,COG0133@2	NA|NA|NA	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
AHPHCOMF_00595	322159.STER_1550	3.3e-98	364.4	Bacilli	trpF	GO:0000162,GO:0003674,GO:0003824,GO:0004425,GO:0004640,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.48,4.2.1.160,4.2.1.20,5.3.1.24	ko:K01696,ko:K01817,ko:K13498,ko:K22100	ko00260,ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map00790,map01100,map01110,map01130,map01230	M00023,M00840	R00674,R02340,R02722,R03508,R03509,R11072	RC00209,RC00210,RC00700,RC00701,RC00944,RC00945,RC02868,RC03343	ko00000,ko00001,ko00002,ko01000			iJN678.trpF,iPC815.YPO2205,iSBO_1134.SBO_1804,iSDY_1059.SDY_1330	Bacteria	1V6Y0@1239,4HK18@91061,COG0135@1,COG0135@2	NA|NA|NA	E	belongs to the TrpF family
AHPHCOMF_00596	322159.STER_1551	2.5e-133	481.5	Bacilli	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48,5.3.1.24	ko:K01609,ko:K01817,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000				Bacteria	1TR94@1239,4HG9K@91061,COG0134@1,COG0134@2	NA|NA|NA	E	Belongs to the TrpC family
AHPHCOMF_00597	322159.STER_1552	7.8e-180	636.3	Bacilli	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP8U@1239,4H9KQ@91061,COG0547@1,COG0547@2	NA|NA|NA	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AHPHCOMF_00598	264199.stu1592	3.6e-105	387.5	Bacilli	trpG		2.4.2.18,2.6.1.85,4.1.3.27	ko:K00766,ko:K01658,ko:K01664,ko:K13497	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01073,R01716	RC00010,RC00440,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000				Bacteria	1V4RM@1239,4HHD8@91061,COG0512@1,COG0512@2	NA|NA|NA	EH	anthranilate
AHPHCOMF_00599	322159.STER_1554	2.4e-256	891.0	Bacilli	trpE	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQAP@1239,4HB31@91061,COG0147@1,COG0147@2	NA|NA|NA	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AHPHCOMF_00600	322159.STER_1555	3.7e-42	177.2	Bacteria	pchB		2.5.1.19,4.2.1.10,4.2.99.21,5.4.99.5	ko:K00800,ko:K03785,ko:K04092,ko:K04782	ko00400,ko01053,ko01100,ko01110,ko01130,ko01230,map00400,map01053,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R03084,R03460,R06602	RC00350,RC00848,RC01549,RC02148,RC03116	ko00000,ko00001,ko00002,ko01000				Bacteria	COG1605@1,COG1605@2	NA|NA|NA	E	Chorismate mutase
AHPHCOMF_00601	1046629.Ssal_00451	3.2e-56	224.2	Bacilli													Bacteria	1VCIA@1239,2C4MC@1,32RSW@2,4HKKA@91061	NA|NA|NA		
AHPHCOMF_00602	322159.STER_1558	0.0	1489.2	Bacilli	ctpE			ko:K12952					ko00000,ko01000	3.A.3.23			Bacteria	1TPF5@1239,4H9ZI@91061,COG0474@1,COG0474@2	NA|NA|NA	P	E1-E2 ATPase
AHPHCOMF_00603	563038.HMPREF0851_01449	3.9e-26	124.4	Bacilli													Bacteria	1W3A8@1239,2DEIC@1,2ZN3X@2,4HZMP@91061	NA|NA|NA		
AHPHCOMF_00604	264199.stu1598	1.2e-43	182.2	Bacilli	yaaK			ko:K09747					ko00000				Bacteria	1VA1S@1239,4HKH3@91061,COG0718@1,COG0718@2	NA|NA|NA	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AHPHCOMF_00605	264199.stu1599	9.7e-28	128.6	Bacilli													Bacteria	1VFYX@1239,4HNKT@91061,COG2963@1,COG2963@2	NA|NA|NA	L	transposase activity
AHPHCOMF_00606	264199.stu1600	2.7e-129	468.0	Bacilli													Bacteria	1UZ0H@1239,4HGGU@91061,COG0789@1,COG0789@2	NA|NA|NA	K	transcriptional regulator, MerR family
AHPHCOMF_00607	264199.stu1601	1.4e-104	385.6	Bacilli	dnaQ		2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1V8EQ@1239,4HJYT@91061,COG0847@1,COG0847@2	NA|NA|NA	L	DNA polymerase III
AHPHCOMF_00608	322159.STER_1564	1.2e-41	176.4	Bacilli	WQ51_02910												Bacteria	1VNC1@1239,2EHT6@1,33BIW@2,4HRJ5@91061	NA|NA|NA	S	Protein of unknown function, DUF536
AHPHCOMF_00609	264199.stu1603	4.8e-63	246.9	Bacilli	XK27_02560			ko:K02612	ko00360,ko01120,map00360,map01120		R09838	RC02690	ko00000,ko00001				Bacteria	1VX9Z@1239,4HXCM@91061,COG2151@1,COG2151@2	NA|NA|NA	S	cog cog2151
AHPHCOMF_00610	264199.stu1604	0.0	1134.8	Bacilli	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP1R@1239,4H9ZG@91061,COG0129@1,COG0129@2	NA|NA|NA	E	Belongs to the IlvD Edd family
AHPHCOMF_00611	264199.stu1605	7.7e-227	792.7	Bacilli	ytfP			ko:K07007					ko00000				Bacteria	1TQ6E@1239,4HAAT@91061,COG2081@1,COG2081@2	NA|NA|NA	S	Flavoprotein
AHPHCOMF_00613	264199.stu1606	3.1e-121	441.0	Bacilli	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.297,2.1.1.33	ko:K02493,ko:K03439			R10806	RC00003,RC03279	ko00000,ko01000,ko03012,ko03016				Bacteria	1TQCA@1239,4HC08@91061,COG0220@1,COG0220@2	NA|NA|NA	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
AHPHCOMF_00614	264199.stu1607	1.2e-151	542.3	Bacilli	ytmP		2.7.1.89	ko:K07251	ko00730,ko01100,map00730,map01100		R02134	RC00002,RC00017	ko00000,ko00001,ko01000				Bacteria	1UMFY@1239,4HBF9@91061,COG0510@1,COG0510@2	NA|NA|NA	M	Phosphotransferase
AHPHCOMF_00615	322159.STER_1571	3e-182	644.4	Bacilli	ecsB			ko:K01992		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1V1VG@1239,4HG1K@91061,COG4473@1,COG4473@2	NA|NA|NA	U	ABC transporter
AHPHCOMF_00616	264199.stu1609	2.3e-133	481.5	Bacilli	ecsA			ko:K01990		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1TQIH@1239,4HA2B@91061,COG1131@1,COG1131@2	NA|NA|NA	V	abc transporter atp-binding protein
AHPHCOMF_00617	322159.STER_1573	3.9e-72	277.3	Bacilli	hit			ko:K02503					ko00000,ko04147				Bacteria	1V9ZJ@1239,4HIG2@91061,COG0537@1,COG0537@2	NA|NA|NA	FG	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
AHPHCOMF_00618	663952.SDD27957_09400	5.6e-12	77.0	Streptococcus dysgalactiae group													Bacteria	1M9TI@119603,1TXCR@1239,29RS1@1,30CVR@2,4I6AJ@91061	NA|NA|NA		
AHPHCOMF_00619	322159.STER_1576	8.1e-106	389.8	Firmicutes													Bacteria	1V92M@1239,2AIHW@1,318ZT@2	NA|NA|NA		
AHPHCOMF_00620	322159.STER_1578	0.0	1343.6	Bacilli	clpL			ko:K04086					ko00000,ko03110				Bacteria	1TRHP@1239,4HAHZ@91061,COG0542@1,COG0542@2	NA|NA|NA	O	ATP-dependent Clp protease ATP-binding subunit
AHPHCOMF_00621	322159.STER_1579	6.9e-206	723.0	Bacilli	ylbM												Bacteria	1TPP2@1239,4HAZJ@91061,COG1323@1,COG1323@2	NA|NA|NA	S	Belongs to the UPF0348 family
AHPHCOMF_00622	322159.STER_1580	2e-140	505.0	Bacilli	yqeM												Bacteria	1V24K@1239,4HDFY@91061,COG0500@1,COG2226@2	NA|NA|NA	Q	Methyltransferase domain protein
AHPHCOMF_00623	322159.STER_1581	6e-58	229.9	Bacilli	rsfS	GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113		ko:K09710					ko00000,ko03009				Bacteria	1VA2Z@1239,4HKEJ@91061,COG0799@1,COG0799@2	NA|NA|NA	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
AHPHCOMF_00624	264199.stu1618	1.4e-107	395.6	Bacilli	nadD		2.7.6.3,2.7.7.18	ko:K00950,ko:K00969,ko:K06950	ko00760,ko00790,ko01100,map00760,map00790,map01100	M00115,M00126,M00841	R00137,R03005,R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	1V6Y1@1239,4HHRY@91061,COG1713@1,COG1713@2	NA|NA|NA	H	HD superfamily hydrolase involved in NAD metabolism
AHPHCOMF_00625	322159.STER_1583	3.1e-118	431.0	Bacilli	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18,3.6.1.55	ko:K00969,ko:K03574	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400				Bacteria	1V3SK@1239,4HGXK@91061,COG1057@1,COG1057@2	NA|NA|NA	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AHPHCOMF_00626	264199.stu1620	3.5e-49	200.7	Bacilli	yhbY	GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275		ko:K07574					ko00000,ko03009				Bacteria	1VEGM@1239,4HKC7@91061,COG1534@1,COG1534@2	NA|NA|NA	J	RNA-binding protein
AHPHCOMF_00627	322159.STER_1585	8.4e-215	752.7	Bacilli	yqeH	GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113		ko:K06948					ko00000,ko03009				Bacteria	1TPM2@1239,4HAAF@91061,COG1161@1,COG1161@2	NA|NA|NA	S	in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
AHPHCOMF_00628	264199.stu1622	1.8e-98	365.2	Bacilli	yqeG			ko:K07015					ko00000				Bacteria	1V6KM@1239,4HGAV@91061,COG2179@1,COG2179@2	NA|NA|NA	S	hydrolase of the HAD superfamily
AHPHCOMF_00629	322159.STER_1587	1.1e-153	549.3	Bacilli	yicL												Bacteria	1TR6G@1239,4HAMD@91061,COG0697@1,COG0697@2	NA|NA|NA	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
AHPHCOMF_00630	264199.stu1624	1.3e-57	228.8	Firmicutes													Bacteria	1VBNR@1239,2B9ZC@1,323D0@2	NA|NA|NA		
AHPHCOMF_00631	264199.stu1625	2.3e-273	947.6	Bacilli	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.12,6.3.5.6,6.3.5.7	ko:K01876,ko:K02434	ko00970,ko01100,map00970,map01100	M00359,M00360	R03905,R04212,R05577	RC00010,RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029				Bacteria	1TPG3@1239,4HAFB@91061,COG0064@1,COG0064@2	NA|NA|NA	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AHPHCOMF_00632	264199.stu1626	3.5e-269	933.7	Bacilli	gatA		6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100		R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029				Bacteria	1TP0C@1239,4HBAZ@91061,COG0154@1,COG0154@2	NA|NA|NA	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
AHPHCOMF_00633	1046629.Ssal_00409	1.4e-47	195.3	Bacilli	gatC		6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100		R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029			iAF987.Gmet_0076	Bacteria	1VEK3@1239,4HNNA@91061,COG0721@1,COG0721@2	NA|NA|NA	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AHPHCOMF_00634	264199.stu1629	6.3e-31	139.4	Bacteria													Bacteria	COG1442@1,COG1442@2	NA|NA|NA	M	lipopolysaccharide 3-alpha-galactosyltransferase activity
AHPHCOMF_00635	904306.HMPREF9192_0728	2.9e-148	531.2	Bacilli	ascB		3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500		R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000		GT1		Bacteria	1TP19@1239,4HA1W@91061,COG2723@1,COG2723@2	NA|NA|NA	G	Belongs to the glycosyl hydrolase 1 family
AHPHCOMF_00636	264199.stu1631	5.1e-77	293.5	Bacilli	ascB		3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500		R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000		GT1		Bacteria	1TP19@1239,4HA1W@91061,COG2723@1,COG2723@2	NA|NA|NA	G	Belongs to the glycosyl hydrolase 1 family
AHPHCOMF_00637	264199.stu1632	1e-95	355.9	Bacilli	msrA		1.8.4.11,1.8.4.12	ko:K07304,ko:K12267					ko00000,ko01000				Bacteria	1TQ3E@1239,4HAIV@91061,COG0225@1,COG0225@2	NA|NA|NA	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AHPHCOMF_00638	322159.STER_1597	1.1e-153	549.3	Bacilli	hlpA			ko:K02073	ko02010,map02010	M00238			ko00000,ko00001,ko00002,ko02000	3.A.1.24			Bacteria	1TQAS@1239,4HCTA@91061,COG1464@1,COG1464@2	NA|NA|NA	M	Belongs to the NlpA lipoprotein family
AHPHCOMF_00639	322159.STER_1598	6.8e-101	373.2	Bacilli	pncA			ko:K16788					ko00000,ko02000	2.A.88.5		iSB619.SA_RS09955	Bacteria	1V1CY@1239,4HFRS@91061,COG1335@1,COG1335@2	NA|NA|NA	Q	isochorismatase
AHPHCOMF_00640	264199.stu1635	1.2e-140	505.8	Bacilli	codY	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0044424,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141		ko:K03706					ko00000,ko03000				Bacteria	1TS7A@1239,4HA9U@91061,COG4465@1,COG4465@2	NA|NA|NA	K	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AHPHCOMF_00641	322159.STER_1600	3.7e-240	837.0	Bacilli	alaA	GO:0003674,GO:0003824,GO:0004021,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0019842,GO:0030170,GO:0030632,GO:0032787,GO:0033554,GO:0036094,GO:0040007,GO:0042221,GO:0042851,GO:0042852,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0046677,GO:0047635,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.2,2.6.1.66	ko:K00814,ko:K14260	ko00220,ko00250,ko00290,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00220,map00250,map00290,map00710,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00171	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007			iNJ661.Rv0337c	Bacteria	1TP0J@1239,4HD83@91061,COG0436@1,COG0436@2	NA|NA|NA	E	Aminotransferase
AHPHCOMF_00642	264199.stu1637	2.4e-75	288.1	Bacilli	XK27_03180			ko:K03499,ko:K06149					ko00000,ko02000	2.A.38.1,2.A.38.4			Bacteria	1V3NY@1239,4HIP3@91061,COG0589@1,COG0589@2	NA|NA|NA	T	universal stress protein
AHPHCOMF_00645	264199.stu1640	2e-157	561.6	Bacilli	pflA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0018307,GO:0019538,GO:0033554,GO:0036211,GO:0043170,GO:0043364,GO:0043365,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070283,GO:0071704,GO:1901564	1.97.1.4	ko:K04069			R04710		ko00000,ko01000			iECOK1_1307.ECOK1_0925,iEcE24377_1341.EcE24377A_0980,iEcSMS35_1347.EcSMS35_2219,iYL1228.KPN_00930	Bacteria	1TPK2@1239,4HACV@91061,COG1180@1,COG1180@2	NA|NA|NA	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AHPHCOMF_00646	264199.stu1641	2e-239	834.7	Bacilli	hlyX			ko:K03699					ko00000,ko02042				Bacteria	1TPN0@1239,4H9SB@91061,COG1253@1,COG1253@2	NA|NA|NA	S	COG1253 Hemolysins and related proteins containing CBS domains
AHPHCOMF_00647	264199.stu1642	2.4e-144	518.1	Bacilli	modF	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	3.6.3.21,3.6.3.34	ko:K02013,ko:K02028,ko:K05776	ko02010,map02010	M00189,M00236,M00240			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14,3.A.1.3			Bacteria	1TRR4@1239,4HB4U@91061,COG1119@1,COG1119@2	NA|NA|NA	P	abc transporter atp-binding protein
AHPHCOMF_00648	322159.STER_1608	0.0	1272.3	Bacilli	yjcE	GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600		ko:K03316					ko00000	2.A.36			Bacteria	1TR4G@1239,4HBJR@91061,COG0025@1,COG0025@2	NA|NA|NA	P	NhaP-type Na H and K H antiporters
AHPHCOMF_00650	264199.stu1645	1.4e-98	365.5	Bacilli	ytqB		2.1.1.176	ko:K03500					ko00000,ko01000,ko03009				Bacteria	1UHQD@1239,4HIMC@91061,COG0144@1,COG0144@2	NA|NA|NA	J	(SAM)-dependent
AHPHCOMF_00651	264199.stu1646	1.3e-184	652.1	Bacilli	yhcC	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540		ko:K07139					ko00000				Bacteria	1TQ57@1239,4H9N8@91061,COG1242@1,COG1242@2	NA|NA|NA	S	radical SAM protein
AHPHCOMF_00652	322159.STER_1612	2.2e-196	691.4	Bacilli	ylbL			ko:K07177	ko02024,map02024				ko00000,ko00001,ko01002				Bacteria	1TRUF@1239,4HBAY@91061,COG3480@1,COG3480@2	NA|NA|NA	T	Belongs to the peptidase S16 family
AHPHCOMF_00653	322159.STER_1613	2.7e-88	331.3	Bacilli	coaD		2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000				Bacteria	1V3MR@1239,4HH47@91061,COG0669@1,COG0669@2	NA|NA|NA	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AHPHCOMF_00654	264199.stu1649	5.1e-93	347.1	Bacilli	rsmD		2.1.1.171	ko:K08316			R07234	RC00003	ko00000,ko01000,ko03009				Bacteria	1V3JF@1239,4HGXT@91061,COG0742@1,COG0742@2	NA|NA|NA	L	Methyltransferase
AHPHCOMF_00655	264199.stu1650	1.9e-172	611.7	Bacilli	trxB		1.8.1.9	ko:K00384	ko00450,map00450		R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000				Bacteria	1TNZS@1239,4HA4N@91061,COG0492@1,COG0492@2	NA|NA|NA	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
AHPHCOMF_00656	40041.SZO_03890	1.9e-09	68.2	Streptococcus dysgalactiae group													Bacteria	1M9T3@119603,1TXCH@1239,29I01@1,304X3@2,4I6AC@91061	NA|NA|NA	S	Protein of unknown function (DUF4059)
AHPHCOMF_00657	322159.STER_1617	4.5e-132	477.2	Bacilli	tcyN		3.6.3.21	ko:K02028,ko:K10010,ko:K16960,ko:K16963	ko02010,map02010	M00234,M00236,M00585,M00586			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.10,3.A.1.3.13,3.A.1.3.14			Bacteria	1TNYD@1239,4H9WY@91061,COG1126@1,COG1126@2	NA|NA|NA	E	abc transporter atp-binding protein
AHPHCOMF_00658	264199.stu1653	1e-162	579.3	Bacilli	yxeN			ko:K02029,ko:K16959,ko:K16962	ko02010,map02010	M00236,M00585,M00586			ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.13			Bacteria	1UZ2C@1239,4HF77@91061,COG0765@1,COG0765@2	NA|NA|NA	P	ABC transporter (Permease
AHPHCOMF_00659	264199.stu1654	1.5e-152	545.4	Bacilli	yxeM			ko:K02030		M00236			ko00000,ko00002,ko02000	3.A.1.3			Bacteria	1V7WQ@1239,4HK1Z@91061,COG0834@1,COG0834@2	NA|NA|NA	ET	ABC-type amino acid transport signal transduction systems, periplasmic component domain
AHPHCOMF_00661	322159.STER_1621	3.1e-206	724.2	Bacilli	dinB	GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031668,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904	2.7.7.7	ko:K02346					ko00000,ko01000,ko03400				Bacteria	1TP42@1239,4HADJ@91061,COG0389@1,COG0389@2	NA|NA|NA	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AHPHCOMF_00662	264199.stu1657	0.0	1574.7	Bacilli	pflB		2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120		R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000				Bacteria	1TPTF@1239,4H9RD@91061,COG1882@1,COG1882@2	NA|NA|NA	C	formate acetyltransferase'
AHPHCOMF_00663	322159.STER_1623	1.8e-147	528.5	Bacilli	cah		4.2.1.1	ko:K01674	ko00910,map00910		R00132,R10092	RC02807	ko00000,ko00001,ko01000				Bacteria	1V16J@1239,4HA62@91061,COG3338@1,COG3338@2	NA|NA|NA	P	carbonic anhydrase
AHPHCOMF_00664	322159.STER_1624	2.1e-85	321.6	Bacilli	yjcF			ko:K02348					ko00000				Bacteria	1VA2J@1239,4HKF5@91061,COG2153@1,COG2153@2	NA|NA|NA	S	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AHPHCOMF_00665	264199.stu1660	1e-44	185.7	Bacteria	hsdS_1		3.1.21.3	ko:K01154					ko00000,ko01000,ko02048				Bacteria	COG0732@1,COG0732@2	NA|NA|NA	V	type I restriction modification DNA specificity domain
AHPHCOMF_00666	322159.STER_1626	2.9e-87	327.8	Bacilli				ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	1V5Y6@1239,4HHGT@91061,COG1196@1,COG1196@2	NA|NA|NA	D	nuclear chromosome segregation
AHPHCOMF_00667	322159.STER_1627	1.5e-127	462.2	Bacilli	ybbM	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771		ko:K02069		M00211			ko00000,ko00002,ko02000	9.B.25.1			Bacteria	1UY1N@1239,4HDM4@91061,COG0390@1,COG0390@2	NA|NA|NA	S	transport system, permease component
AHPHCOMF_00668	322159.STER_1628	3.6e-117	427.6	Bacilli	ybbL	GO:0005575,GO:0005623,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0016020,GO:0019725,GO:0030003,GO:0042592,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071944,GO:0098771		ko:K02065,ko:K02068	ko02010,map02010	M00210,M00211,M00669,M00670			ko00000,ko00001,ko00002,ko02000	3.A.1.27			Bacteria	1V3DQ@1239,4HHGU@91061,COG4619@1,COG4619@2	NA|NA|NA	S	abc transporter atp-binding protein
AHPHCOMF_00669	264199.stu1667	6.5e-184	649.8	Bacilli	ampC												Bacteria	1TNZX@1239,4IPJT@91061,COG1680@1,COG1680@2	NA|NA|NA	V	COG1680 Beta-lactamase class C and other penicillin binding proteins
AHPHCOMF_00670	322159.STER_1630	1.7e-139	501.9	Bacilli	cppA												Bacteria	1VMPM@1239,4HSVM@91061,COG0346@1,COG0346@2	NA|NA|NA	E	CppA N-terminal
AHPHCOMF_00671	1046629.Ssal_00366	5e-44	183.7	Bacteria				ko:K07052					ko00000				Bacteria	COG1266@1,COG1266@2	NA|NA|NA	V	CAAX protease self-immunity
AHPHCOMF_00672	264199.stu1671	2.3e-164	584.7	Bacilli	gla			ko:K02440					ko00000,ko02000	1.A.8.1,1.A.8.2			Bacteria	1TP4T@1239,4HE39@91061,COG0580@1,COG0580@2	NA|NA|NA	U	Belongs to the MIP aquaporin (TC 1.A.8) family
AHPHCOMF_00673	322159.STER_1633	0.0	1521.1	Bacilli	pepX		3.4.14.11	ko:K01281					ko00000,ko01000,ko01002				Bacteria	1TT78@1239,4HBA0@91061,COG2936@1,COG2936@2	NA|NA|NA	E	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
AHPHCOMF_00676	322159.STER_1636	6.8e-47	193.0	Bacteria	spiA			ko:K18831					ko00000,ko02048,ko03000				Bacteria	COG1476@1,COG1476@2	NA|NA|NA	K	sequence-specific DNA binding
AHPHCOMF_00677	264199.stu1676	2.9e-28	130.6	Bacilli	blpT												Bacteria	1W6SH@1239,2DWQH@1,341F6@2,4HX74@91061	NA|NA|NA		
AHPHCOMF_00678	322159.STER_1638	1.2e-91	342.8	Bacilli	blpT												Bacteria	1W6SH@1239,2DWQH@1,341F6@2,4HX74@91061	NA|NA|NA		
AHPHCOMF_00679	264199.stu0797	3.9e-122	444.1	Bacilli				ko:K07483					ko00000				Bacteria	1V2T5@1239,4HFZ1@91061,COG2963@1,COG2963@2	NA|NA|NA	L	Transposase
AHPHCOMF_00680	264199.stu0796	3.6e-165	587.4	Firmicutes													Bacteria	1TQEG@1239,COG2801@1,COG2801@2	NA|NA|NA	L	integrase core domain
AHPHCOMF_00685	862971.SANR_0567	4.3e-25	120.2	Streptococcus anginosus group													Bacteria	1TVYK@1239,2DITH@1,3043M@2,42EF9@671232,4I4KQ@91061	NA|NA|NA	S	Bacteriocin class II with double-glycine leader peptide
AHPHCOMF_00688	322159.STER_1649	4e-133	480.7	Bacteria	agrA			ko:K07707	ko02020,ko02024,map02020,map02024	M00495			ko00000,ko00001,ko00002,ko02022				Bacteria	COG3279@1,COG3279@2	NA|NA|NA	KT	phosphorelay signal transduction system
AHPHCOMF_00689	322159.STER_1650	9.9e-239	832.4	Bacteria	blpH		2.7.13.3	ko:K07706	ko02020,ko02024,map02020,map02024	M00495			ko00000,ko00001,ko00002,ko01000,ko01001,ko02022				Bacteria	COG3290@1,COG3290@2	NA|NA|NA	T	protein histidine kinase activity
AHPHCOMF_00691	322159.STER_1652	1.6e-236	825.1	Bacilli	mesE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K20345	ko02024,map02024				ko00000,ko00001,ko02000	3.A.1.112,8.A.1			Bacteria	1V5C8@1239,4HHKB@91061,COG0845@1,COG0845@2	NA|NA|NA	M	Transport protein ComB
AHPHCOMF_00692	322159.STER_1653	0.0	1378.2	Bacilli	comA			ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024				ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.21			Bacteria	1V77J@1239,4HAX2@91061,COG2274@1,COG2274@2	NA|NA|NA	V	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
AHPHCOMF_00693	322159.STER_1656	0.0	1088.6	Bacilli	mdlB	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008144,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0031224,GO:0032553,GO:0032555,GO:0032559,GO:0033036,GO:0034040,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363		ko:K06147,ko:K18890	ko02010,map02010	M00707			ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21			Bacteria	1TP0B@1239,4HA3S@91061,COG1132@1,COG1132@2	NA|NA|NA	V	abc transporter atp-binding protein
AHPHCOMF_00694	264199.stu1694	0.0	1110.5	Bacilli	mdlA	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016021,GO:0017076,GO:0030554,GO:0031224,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363		ko:K06148,ko:K18889	ko02010,map02010	M00707			ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.106.13,3.A.1.106.5			Bacteria	1TP0B@1239,4HA3S@91061,COG1132@1,COG1132@2	NA|NA|NA	V	abc transporter atp-binding protein
AHPHCOMF_00696	264199.stu1695	1.7e-93	348.6	Bacilli	XK27_09885												Bacteria	1VKIA@1239,4HQZW@91061,COG4767@1,COG4767@2	NA|NA|NA	V	Glycopeptide antibiotics resistance protein
AHPHCOMF_00697	264199.stu1696	3e-223	780.8	Bacilli	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941					ko00000,ko01000,ko03009				Bacteria	1TPVF@1239,4H9NU@91061,COG0820@1,COG0820@2	NA|NA|NA	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AHPHCOMF_00698	264199.stu1697	2.3e-72	278.9	Bacilli	yutD												Bacteria	1VA85@1239,4HKF7@91061,COG4470@1,COG4470@2	NA|NA|NA	J	protein conserved in bacteria
AHPHCOMF_00699	322159.STER_1662	1.3e-270	938.3	Bacilli	yunD		3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110		R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000				Bacteria	1TQCW@1239,4HAUC@91061,COG0737@1,COG0737@2	NA|NA|NA	F	Belongs to the 5'-nucleotidase family
AHPHCOMF_00701	322159.STER_1664	1.4e-221	775.4	Bacilli	cshB	GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363	3.6.4.13	ko:K05592,ko:K18692	ko03018,map03018				ko00000,ko00001,ko01000,ko03009,ko03019				Bacteria	1TPAP@1239,4HA98@91061,COG0513@1,COG0513@2	NA|NA|NA	JKL	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
AHPHCOMF_00702	322159.STER_1665	6.3e-185	653.3	Bacilli	mraY	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502		R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146		iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105	Bacteria	1TP8W@1239,4H9TP@91061,COG0472@1,COG0472@2	NA|NA|NA	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AHPHCOMF_00703	264199.stu1701	0.0	1454.1	Bacilli	ftsI	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681	3.4.16.4	ko:K03587,ko:K08384,ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501				ko00000,ko00001,ko01000,ko01011,ko03036			iSSON_1240.SSON_0092	Bacteria	1TP93@1239,4H9VQ@91061,COG0768@1,COG0768@2	NA|NA|NA	M	penicillin-binding protein
AHPHCOMF_00704	322159.STER_1667	8.1e-46	189.5	Bacilli	ftsL												Bacteria	1VCE5@1239,4HM4W@91061,COG4839@1,COG4839@2	NA|NA|NA	D	cell division protein FtsL
AHPHCOMF_00705	322159.STER_1668	3.9e-173	614.0	Bacilli	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438					ko00000,ko01000,ko03009				Bacteria	1TNZV@1239,4H9U2@91061,COG0275@1,COG0275@2	NA|NA|NA	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
AHPHCOMF_00706	264199.stu1704	4.7e-65	253.8	Bacilli													Bacteria	1W5UA@1239,2DDKD@1,2ZIF1@2,4HZND@91061	NA|NA|NA		
AHPHCOMF_00707	264199.stu1704	2.7e-52	211.1	Bacilli													Bacteria	1W5UA@1239,2DDKD@1,2ZIF1@2,4HZND@91061	NA|NA|NA		
AHPHCOMF_00709	1046629.Ssal_00333	8.7e-33	146.4	Bacilli	yhaI												Bacteria	1V90R@1239,4HQ7Q@91061,COG3152@1,COG3152@2	NA|NA|NA	J	Protein of unknown function (DUF805)
AHPHCOMF_00710	435842.HMPREF0848_01480	4.5e-18	97.1	Bacteria													Bacteria	COG1196@1,COG1196@2	NA|NA|NA	D	nuclear chromosome segregation
AHPHCOMF_00711	322159.STER_1675	2e-225	788.1	Bacilli	proA	GO:0003674,GO:0003824,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000			iB21_1397.B21_00243,iECBD_1354.ECBD_3376,iECB_1328.ECB_00240,iECD_1391.ECD_00240,iLJ478.TM0293,iYL1228.KPN_00280,iYO844.BSU13130	Bacteria	1TQ9V@1239,4HB7B@91061,COG0014@1,COG0014@2	NA|NA|NA	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AHPHCOMF_00712	904306.HMPREF9192_0659	1.7e-140	505.4	Bacilli	proB	GO:0003674,GO:0003824,GO:0004349,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016772,GO:0016774,GO:0016903,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPG6@1239,4HA9B@91061,COG0263@1,COG0263@2	NA|NA|NA	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AHPHCOMF_00713	322159.STER_1677	2.2e-285	987.6	Bacilli	XK27_00765			ko:K01992		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1TSZA@1239,28MBB@1,2ZAPV@2,4HDKH@91061	NA|NA|NA		
AHPHCOMF_00714	1046629.Ssal_00328	8.1e-134	483.0	Bacilli	ecsA_2			ko:K01990		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1TQIH@1239,4HCEU@91061,COG1131@1,COG1131@2	NA|NA|NA	V	abc transporter atp-binding protein
AHPHCOMF_00715	1046629.Ssal_00327	5.2e-125	453.8	Bacilli				ko:K07150					ko00000				Bacteria	1TQWV@1239,4HEYY@91061,COG1811@1,COG1811@2	NA|NA|NA	S	Protein of unknown function (DUF554)
AHPHCOMF_00716	322159.STER_1681	0.0	2318.1	Bacilli	addA		3.6.4.12	ko:K16898					ko00000,ko01000,ko03400				Bacteria	1TQ35@1239,4HA64@91061,COG1074@1,COG1074@2	NA|NA|NA	L	ATP-dependent helicase nuclease subunit A
AHPHCOMF_00717	264199.stu1717	0.0	2132.8	Bacilli	rexB	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.21.3,3.6.4.12	ko:K01153,ko:K16899					ko00000,ko01000,ko02048,ko03400				Bacteria	1TQJW@1239,4HAY6@91061,COG3857@1,COG3857@2	NA|NA|NA	L	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AHPHCOMF_00718	322159.STER_1683	2.6e-121	441.4	Bacilli	liaI			ko:K11619	ko02020,map02020	M00754			ko00000,ko00001,ko00002				Bacteria	1VGSF@1239,4IRBC@91061,COG4758@1,COG4758@2	NA|NA|NA	S	membrane
AHPHCOMF_00719	322159.STER_1684	5.2e-75	287.0	Bacilli	XK27_02470												Bacteria	1VBF7@1239,4HMZX@91061,COG3279@1,COG3279@2	NA|NA|NA	K	LytTr DNA-binding domain
AHPHCOMF_00720	1046629.Ssal_00311	3.6e-66	258.1	Bacteria													Bacteria	COG4640@1,COG4640@2	NA|NA|NA	KT	response to antibiotic
AHPHCOMF_00721	435842.HMPREF0848_01381	1.5e-80	306.2	Bacilli	yebC			ko:K16637					ko00000,ko02042				Bacteria	1VK5M@1239,4HS44@91061,COG3064@1,COG3064@2	NA|NA|NA	M	Membrane
AHPHCOMF_00722	904306.HMPREF9192_0644	2.9e-18	97.1	Bacilli	yebC			ko:K16637					ko00000,ko02042				Bacteria	1VK5M@1239,4HS44@91061,COG3064@1,COG3064@2	NA|NA|NA	M	Membrane
AHPHCOMF_00723	322159.STER_1689	4.3e-261	906.7	Bacilli	XK27_03190		5.2.1.8	ko:K03768,ko:K16785	ko02010,map02010	M00582			ko00000,ko00001,ko00002,ko01000,ko02000,ko03110	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35			Bacteria	1TSZZ@1239,4HB54@91061,COG0561@1,COG0561@2,COG4696@1,COG4696@2	NA|NA|NA	S	hydrolases of the HAD superfamily
AHPHCOMF_00724	322159.STER_1690	3.8e-173	614.0	Bacilli	ansA		3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110		R00485	RC00010,RC02798	ko00000,ko00001,ko01000				Bacteria	1TPP9@1239,4H9YJ@91061,COG0252@1,COG0252@2	NA|NA|NA	EJ	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
AHPHCOMF_00726	264199.stu1725	0.0	1313.5	Bacilli	recG	GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494	3.6.4.12	ko:K03655	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1TQ6I@1239,4HAWN@91061,COG1200@1,COG1200@2	NA|NA|NA	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AHPHCOMF_00727	264199.stu1726	1.7e-183	648.7	Bacilli	alr		5.1.1.1,5.1.1.5	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502		R00401	RC00285	ko00000,ko00001,ko01000,ko01011				Bacteria	1TNYY@1239,4HA95@91061,COG0787@1,COG0787@2	NA|NA|NA	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AHPHCOMF_00728	264199.stu1727	4.5e-61	240.4	Bacilli	acpS		2.7.6.3,2.7.8.7,5.1.1.1	ko:K00950,ko:K00997,ko:K01775	ko00473,ko00770,ko00790,ko01100,ko01502,map00473,map00770,map00790,map01100,map01502	M00126,M00841	R00401,R01625,R03503	RC00002,RC00017,RC00285	ko00000,ko00001,ko00002,ko01000,ko01011			iYO844.BSU04620	Bacteria	1VA0T@1239,4HKBI@91061,COG0736@1,COG0736@2	NA|NA|NA	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
AHPHCOMF_00729	322159.STER_1703	1.1e-197	695.7	Firmicutes	aroF		2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000			iHN637.CLJU_RS07240	Bacteria	1TQI4@1239,COG0722@1,COG0722@2	NA|NA|NA	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AHPHCOMF_00730	264199.stu1729	2.9e-198	697.6	Firmicutes	aroF		2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000			iHN637.CLJU_RS07240	Bacteria	1TQI4@1239,COG0722@1,COG0722@2	NA|NA|NA	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AHPHCOMF_00731	264199.stu1730	0.0	1660.6	Bacilli	secA	GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680		ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4			Bacteria	1TPEY@1239,4HA22@91061,COG0653@1,COG0653@2	NA|NA|NA	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
AHPHCOMF_00733	264199.stu1732	3e-189	667.5	Bacilli	manA		5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000				Bacteria	1VRGI@1239,4HBFW@91061,COG1482@1,COG1482@2	NA|NA|NA	G	mannose-6-phosphate isomerase
AHPHCOMF_00734	264199.stu1733	4.1e-172	610.5	Bacilli	scrK		2.7.1.2,2.7.1.4	ko:K00845,ko:K00847	ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R00760,R00867,R01600,R01786,R03920	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQU4@1239,4HA1C@91061,COG1940@1,COG1940@2	NA|NA|NA	GK	Fructokinase
AHPHCOMF_00735	264199.stu1734	0.0	1200.3	Bacilli	scrA		2.7.1.208,2.7.1.211	ko:K02756,ko:K02777,ko:K02808,ko:K02809,ko:K02810,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	M00265,M00266,M00268,M00269,M00270,M00271,M00272,M00303,M00806	R00811,R02738,R02780,R04111,R04394,R05132,R08559	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1,4.A.1.1.11,4.A.1.1.12,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9			Bacteria	1TP5X@1239,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2	NA|NA|NA	G	pts system
AHPHCOMF_00736	322159.STER_1711	5.4e-291	1006.1	Bacilli	scrB		3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100		R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000		GH32		Bacteria	1TPAE@1239,4H9Y7@91061,COG1621@1,COG1621@2	NA|NA|NA	G	invertase
AHPHCOMF_00737	322159.STER_1712	7.5e-180	636.3	Bacilli	scrR			ko:K02529,ko:K03484					ko00000,ko03000				Bacteria	1TQ7K@1239,4H9V1@91061,COG1609@1,COG1609@2	NA|NA|NA	K	Transcriptional
AHPHCOMF_00738	264199.stu1738	2.1e-73	281.6	Bacilli	nusB			ko:K03625					ko00000,ko03009,ko03021				Bacteria	1VA9B@1239,4HKMU@91061,COG0781@1,COG0781@2	NA|NA|NA	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AHPHCOMF_00739	322159.STER_1714	3.4e-62	244.2	Bacilli	yqhY			ko:K10947					ko00000,ko03000				Bacteria	1V4IC@1239,4HJ7T@91061,COG1302@1,COG1302@2	NA|NA|NA	S	protein conserved in bacteria
AHPHCOMF_00740	264199.stu1740	9.3e-98	362.8	Bacilli	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576		ko:K02356					ko00000,ko03012				Bacteria	1TR8P@1239,4H9YX@91061,COG0231@1,COG0231@2	NA|NA|NA	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AHPHCOMF_00741	264199.stu1741	3.7e-84	317.4	Bacilli	comEB		3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044				Bacteria	1V8V0@1239,4IQZA@91061,COG2131@1,COG2131@2	NA|NA|NA	F	ComE operon protein 2
AHPHCOMF_00742	322159.STER_1717	5e-193	680.2	Bacilli	pepP	GO:0003674,GO:0003824,GO:0004177,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271,ko:K08326					ko00000,ko01000,ko01002				Bacteria	1TQ44@1239,4HAT7@91061,COG0006@1,COG0006@2	NA|NA|NA	E	Belongs to the peptidase M24B family
AHPHCOMF_00744	904306.HMPREF9192_0620	1.3e-08	66.2	Firmicutes				ko:K01990		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1TPBQ@1239,COG1131@1,COG1131@2	NA|NA|NA	V	'abc transporter, ATP-binding protein
AHPHCOMF_00745	435842.HMPREF0848_01406	1.6e-19	101.3	Firmicutes				ko:K01990		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1TPBQ@1239,COG1131@1,COG1131@2	NA|NA|NA	V	'abc transporter, ATP-binding protein
AHPHCOMF_00746	435842.HMPREF0848_01406	2.4e-60	238.0	Firmicutes				ko:K01990		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1TPBQ@1239,COG1131@1,COG1131@2	NA|NA|NA	V	'abc transporter, ATP-binding protein
AHPHCOMF_00749	322159.STER_1722	0.0	1872.1	Bacilli	uvrA			ko:K03701	ko03420,map03420				ko00000,ko00001,ko03400				Bacteria	1TPIJ@1239,4HAW9@91061,COG0178@1,COG0178@2	NA|NA|NA	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AHPHCOMF_00750	264199.stu1749	2e-169	601.7	Bacilli	corA			ko:K03284					ko00000,ko02000	1.A.35.1,1.A.35.3			Bacteria	1TPI8@1239,4HE7S@91061,COG0598@1,COG0598@2	NA|NA|NA	P	COG0598 Mg2 and Co2 transporters
AHPHCOMF_00751	264199.stu1750	2.6e-123	448.0	Bacilli	XK27_01040												Bacteria	1VF5N@1239,4HJMB@91061,COG4858@1,COG4858@2	NA|NA|NA	S	Pfam PF06570
AHPHCOMF_00753	264199.stu1752	9.7e-36	155.6	Bacilli	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02963,ko:K03111,ko:K15125	ko03010,ko03030,ko03430,ko03440,ko05133,map03010,map03030,map03430,map03440,map05133	M00178			br01610,ko00000,ko00001,ko00002,ko00536,ko03011,ko03029,ko03032,ko03400				Bacteria	1V9XS@1239,4HKCC@91061,COG0238@1,COG0238@2	NA|NA|NA	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AHPHCOMF_00754	264199.stu1753	2.7e-91	341.3	Bacilli	ssb			ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440				ko00000,ko00001,ko03029,ko03032,ko03400				Bacteria	1V3WT@1239,4HH8I@91061,COG0629@1,COG0629@2	NA|NA|NA	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
AHPHCOMF_00755	322159.STER_1728	3.9e-47	193.7	Bacilli	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904		ko:K02990	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011,ko03029				Bacteria	1VA18@1239,4HKHD@91061,COG0360@1,COG0360@2	NA|NA|NA	J	Binds together with S18 to 16S ribosomal RNA
AHPHCOMF_00756	996306.SSUR61_1077	3.6e-41	175.6	Streptococcus suis	XK27_05745												Bacteria	1U8WY@1239,1WSBS@1307,2BJFN@1,32DS8@2,4IIVI@91061	NA|NA|NA		
AHPHCOMF_00757	322159.STER_1730	2.5e-230	804.3	Bacilli	mutY			ko:K03575	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	1TPUT@1239,4H9UM@91061,COG1194@1,COG1194@2	NA|NA|NA	L	A G-specific adenine glycosylase
AHPHCOMF_00762	322159.STER_1736	0.0	1715.3	Bacilli	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440		R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400				Bacteria	1TPKJ@1239,4H9S7@91061,COG0258@1,COG0258@2,COG0749@1,COG0749@2	NA|NA|NA	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AHPHCOMF_00763	322159.STER_1737	0.0	1497.3	Bacilli	mutS2	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391		ko:K07456	ko03430,map03430				ko00000,ko00001,ko03400				Bacteria	1TP5W@1239,4H9NZ@91061,COG1193@1,COG1193@2	NA|NA|NA	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
AHPHCOMF_00764	322159.STER_1738	1e-93	349.4	Bacteria	cvpA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944		ko:K03558					ko00000				Bacteria	COG1286@1,COG1286@2	NA|NA|NA	S	toxin biosynthetic process
AHPHCOMF_00765	1302863.I872_01550	2.3e-13	81.3	Bacilli	zapA	GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000921,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032185,GO:0032505,GO:0032506,GO:0034622,GO:0042802,GO:0043093,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051301,GO:0061640,GO:0065003,GO:0070925,GO:0071840,GO:0090529,GO:1902410,GO:1903047		ko:K09888					ko00000,ko03036				Bacteria	1VFZS@1239,4HP4T@91061,COG3027@1,COG3027@2	NA|NA|NA	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AHPHCOMF_00766	322159.STER_1740	4.7e-160	570.5	Bacilli	rnhC	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470,ko:K03471	ko03030,map03030				ko00000,ko00001,ko01000,ko03032				Bacteria	1TQBE@1239,4H9QR@91061,COG1039@1,COG1039@2	NA|NA|NA	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AHPHCOMF_00767	264199.stu1766	2.6e-112	411.4	Bacilli	lepB		3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060				ko00000,ko00001,ko01000,ko01002				Bacteria	1V7H9@1239,4HJSP@91061,COG0681@1,COG0681@2	NA|NA|NA	U	Belongs to the peptidase S26 family
AHPHCOMF_00768	322159.STER_1742	0.0	1624.0	Bacilli	recD2		3.1.11.5	ko:K03581	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1TPZH@1239,4HATQ@91061,COG0507@1,COG0507@2	NA|NA|NA	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
AHPHCOMF_00769	322159.STER_1743	2e-47	194.9	Bacteria	azlD												Bacteria	COG4392@1,COG4392@2	NA|NA|NA	E	branched-chain amino acid
AHPHCOMF_00770	322159.STER_1744	1.8e-114	418.7	Bacilli	azlC												Bacteria	1V64T@1239,4HH44@91061,COG1296@1,COG1296@2	NA|NA|NA	E	AzlC protein
AHPHCOMF_00771	264199.stu1770	1.9e-186	658.3	Bacilli	tsaD	GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564	2.3.1.234	ko:K01409,ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	R10648	RC00070,RC00416	ko00000,ko00001,ko00002,ko01000,ko02044,ko03016	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4			Bacteria	1TQDR@1239,4HANB@91061,COG0533@1,COG0533@2	NA|NA|NA	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AHPHCOMF_00772	264199.stu1771	3.7e-73	280.8	Bacilli	rimI		2.3.1.128	ko:K03789					ko00000,ko01000,ko03009				Bacteria	1V6KU@1239,4HP50@91061,COG0454@1,COG0456@2	NA|NA|NA	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
AHPHCOMF_00773	322159.STER_1747	5.6e-121	440.3	Bacilli	yeaZ	GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564	2.3.1.234	ko:K01409,ko:K14742			R10648	RC00070,RC00416	ko00000,ko01000,ko03016				Bacteria	1V4YX@1239,4HHD7@91061,COG1214@1,COG1214@2	NA|NA|NA	O	COG1214, inactive homolog of metal-dependent proteases
AHPHCOMF_00774	264199.stu1773	2.5e-33	147.5	Bacilli	ykzG												Bacteria	1VEI7@1239,4HNSK@91061,COG5503@1,COG5503@2	NA|NA|NA	S	Belongs to the UPF0356 family
AHPHCOMF_00775	322159.STER_1749	0.0	1114.0	Bacilli	rnjA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360		ko:K12574	ko03018,map03018				ko00000,ko00001,ko01000,ko03019				Bacteria	1TQ9G@1239,4HAAP@91061,COG0595@1,COG0595@2	NA|NA|NA	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AHPHCOMF_00776	435842.HMPREF0848_01440	2.7e-40	171.4	Bacilli	pscB												Bacteria	1V8WM@1239,4HIMT@91061,COG3942@1,COG3942@2	NA|NA|NA	M	CHAP domain protein
AHPHCOMF_00777	264199.stu1776	1.5e-263	914.8	Bacilli	glnA		6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727		R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147				Bacteria	1TNZA@1239,4HACE@91061,COG0174@1,COG0174@2	NA|NA|NA	E	glutamine synthetase
AHPHCOMF_00778	322159.STER_1752	8.5e-63	246.1	Bacilli	glnR	GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2001141		ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439			ko00000,ko00001,ko00002,ko02000,ko03000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1V6JE@1239,4HKM6@91061,COG0789@1,COG0789@2	NA|NA|NA	K	Transcriptional regulator
AHPHCOMF_00779	322159.STER_1753	1.3e-87	328.9	Bacilli													Bacteria	1VAJG@1239,4HKDZ@91061,COG4129@1,COG4129@2	NA|NA|NA	S	Fusaric acid resistance protein-like
AHPHCOMF_00780	904306.HMPREF9192_0265	1.1e-12	78.2	Bacteria													Bacteria	COG3464@1,COG3464@2	NA|NA|NA		
AHPHCOMF_00781	322159.STER_1755	2e-222	778.1	Bacilli	pgk	GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147			iSB619.SA_RS04145	Bacteria	1TP3H@1239,4H9R3@91061,COG0126@1,COG0126@2	NA|NA|NA	F	Belongs to the phosphoglycerate kinase family
AHPHCOMF_00782	322159.STER_1756	3.2e-42	177.2	Bacilli				ko:K07491					ko00000				Bacteria	1V1CM@1239,4HGN6@91061,COG1943@1,COG1943@2	NA|NA|NA	L	Transposase
AHPHCOMF_00783	322159.STER_1757	1.9e-46	191.4	Bacteria				ko:K07483					ko00000				Bacteria	COG2963@1,COG2963@2	NA|NA|NA	L	transposase activity
AHPHCOMF_00784	322159.STER_0016	7.4e-23	112.5	Firmicutes				ko:K07483					ko00000				Bacteria	1W68S@1239,COG2963@1,COG2963@2	NA|NA|NA	L	Transposase
AHPHCOMF_00785	322159.STER_1759	1.8e-56	224.9	Bacteria				ko:K07497					ko00000				Bacteria	COG2801@1,COG2801@2	NA|NA|NA	L	transposition
AHPHCOMF_00786	322159.STER_1760	9.1e-83	312.8	Firmicutes				ko:K07497					ko00000				Bacteria	1TQQY@1239,COG2801@1,COG2801@2	NA|NA|NA	L	Integrase core domain protein
AHPHCOMF_00787	322159.STER_0151	7e-107	393.3	Firmicutes				ko:K07485					ko00000				Bacteria	1TQ93@1239,COG3464@1,COG3464@2	NA|NA|NA	L	Transposase
AHPHCOMF_00788	322159.STER_1055	1.5e-42	178.3	Firmicutes				ko:K07485					ko00000				Bacteria	1TQ93@1239,COG3464@1,COG3464@2	NA|NA|NA	L	Transposase
AHPHCOMF_00789	322159.STER_1761	1.4e-189	668.7	Bacilli	gap	GO:0000166,GO:0002020,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009986,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019362,GO:0019637,GO:0019674,GO:0019899,GO:0022610,GO:0034641,GO:0036094,GO:0043891,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044464,GO:0044650,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051704,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0097159,GO:0140030,GO:0140032,GO:1901265,GO:1901360,GO:1901363,GO:1901564	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147				Bacteria	1TNYU@1239,4H9NS@91061,COG0057@1,COG0057@2	NA|NA|NA	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
AHPHCOMF_00790	264199.stu1789	0.0	1362.1	Bacilli	fusA	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576		ko:K02355					ko00000,ko03012,ko03029				Bacteria	1TPF9@1239,4HAB8@91061,COG0480@1,COG0480@2	NA|NA|NA	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AHPHCOMF_00791	264199.stu1790	6.7e-81	306.6	Bacilli	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113		ko:K02992	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V1GG@1239,4H9PA@91061,COG0049@1,COG0049@2	NA|NA|NA	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
AHPHCOMF_00792	1046629.Ssal_00226	2.3e-69	268.1	Bacilli	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02950	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V1FJ@1239,4HFMZ@91061,COG0048@1,COG0048@2	NA|NA|NA	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AHPHCOMF_00793	322159.STER_1765	1.1e-142	512.7	Bacilli	purR		2.4.2.7	ko:K00759,ko:K09685	ko00230,ko01100,map00230,map01100		R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko03000,ko04147				Bacteria	1TPN9@1239,4HB8I@91061,COG0503@1,COG0503@2	NA|NA|NA	F	operon repressor
AHPHCOMF_00794	264199.stu1794	3.6e-179	634.0	Bacilli	cbf			ko:K03698					ko00000,ko01000,ko03019				Bacteria	1TPIU@1239,4HB1M@91061,COG3481@1,COG3481@2	NA|NA|NA	S	3'-5' exoribonuclease yhaM
AHPHCOMF_00795	264199.stu1795	6.9e-173	613.6	Bacilli	rmuC			ko:K09760					ko00000				Bacteria	1TPWI@1239,4HE2N@91061,COG1322@1,COG1322@2	NA|NA|NA	S	RmuC domain protein
AHPHCOMF_00796	264199.stu1796	3.1e-118	431.0	Bacilli	thiN		2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100		R00619	RC00002,RC00017	ko00000,ko00001,ko01000				Bacteria	1VA0W@1239,4HHS1@91061,COG1564@1,COG1564@2	NA|NA|NA	H	thiamine pyrophosphokinase
AHPHCOMF_00797	264199.stu1797	3e-119	434.5	Bacilli	rpe		5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQK8@1239,4H9RW@91061,COG0036@1,COG0036@2	NA|NA|NA	G	Belongs to the ribulose-phosphate 3-epimerase family
AHPHCOMF_00798	322159.STER_1770	7.6e-163	579.7	Bacilli	rsgA		3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100		R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009				Bacteria	1TPSQ@1239,4HA9W@91061,COG1162@1,COG1162@2	NA|NA|NA	G	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
AHPHCOMF_00800	264199.stu1799	8.9e-156	556.2	Bacilli	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528			R10716	RC00003,RC03257	ko00000,ko01000,ko03009				Bacteria	1TP9W@1239,4HA4R@91061,COG0030@1,COG0030@2	NA|NA|NA	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
AHPHCOMF_00801	322159.STER_1773	3.2e-98	364.4	Bacilli	rnmV	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360	3.1.26.8	ko:K05985,ko:K07476					ko00000,ko01000				Bacteria	1V3K3@1239,4HH5Y@91061,COG1658@1,COG1658@2	NA|NA|NA	J	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AHPHCOMF_00802	264199.stu1801	4.1e-144	517.3	Bacilli	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575		ko:K03424					ko00000,ko01000				Bacteria	1TNY1@1239,4HA74@91061,COG0084@1,COG0084@2	NA|NA|NA	L	Hydrolase, tatd
AHPHCOMF_00803	264199.stu1802	6.1e-73	280.0	Bacilli	yccU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464		ko:K06929					ko00000				Bacteria	1V7C7@1239,4HIZT@91061,COG1832@1,COG1832@2	NA|NA|NA	S	CoA-binding protein
AHPHCOMF_00804	264199.stu1803	4.8e-51	206.8	Bacilli	trxA			ko:K03671	ko04621,ko05418,map04621,map05418				ko00000,ko00001,ko03110				Bacteria	1VA3Y@1239,4HKKX@91061,COG3118@1,COG3118@2	NA|NA|NA	O	Belongs to the thioredoxin family
AHPHCOMF_00805	264199.stu1804	7.8e-143	513.1	Bacilli													Bacteria	1TQSZ@1239,4HCXD@91061,COG2110@1,COG2110@2	NA|NA|NA	S	Macro domain protein
AHPHCOMF_00806	435842.HMPREF0848_01462	3.1e-10	69.7	Bacilli				ko:K07107					ko00000,ko01000				Bacteria	1VAGM@1239,4HIVC@91061,COG0824@1,COG0824@2	NA|NA|NA	L	thioesterase
AHPHCOMF_00807	322159.STER_1779	1.3e-54	218.8	Bacteria	bta		1.8.1.8	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418				ko00000,ko00001,ko01000,ko03110				Bacteria	COG0526@1,COG0526@2	NA|NA|NA	CO	cell redox homeostasis
AHPHCOMF_00811	322159.STER_1785	1.7e-226	791.6	Bacilli	tgt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773			R03789,R10209	RC00063	ko00000,ko01000,ko03016				Bacteria	1TNZ4@1239,4HCNM@91061,COG0343@1,COG0343@2	NA|NA|NA	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
AHPHCOMF_00812	264199.stu1807	5e-84	317.0	Bacilli				ko:K07491					ko00000				Bacteria	1V1CM@1239,4HGN6@91061,COG1943@1,COG1943@2	NA|NA|NA	L	Transposase
AHPHCOMF_00813	322159.STER_1692	4.7e-249	866.7	Bacilli				ko:K07485					ko00000				Bacteria	1TQ93@1239,4HJK9@91061,COG3464@1,COG3464@2	NA|NA|NA	L	Transposase
AHPHCOMF_00814	1123299.AUKZ01000036_gene1534	1e-13	81.6	Bacteria	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02914	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	COG0230@1,COG0230@2	NA|NA|NA	J	Ribosomal protein L34
AHPHCOMF_00815	322159.STER_1788	2e-186	658.3	Bacilli	jag			ko:K06346					ko00000				Bacteria	1V3IN@1239,4HHHU@91061,COG1847@1,COG1847@2	NA|NA|NA	S	RNA-binding protein
AHPHCOMF_00816	264199.stu1810	7.5e-141	506.5	Bacilli	yidC			ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9			Bacteria	1TQ0J@1239,4HB3J@91061,COG0706@1,COG0706@2	NA|NA|NA	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AHPHCOMF_00817	322159.STER_1790	5.9e-55	219.9	Bacilli	rnpA	GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904	3.1.26.5	ko:K03536,ko:K08998					ko00000,ko01000,ko03016				Bacteria	1VA78@1239,4HKG6@91061,COG0594@1,COG0594@2	NA|NA|NA	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
AHPHCOMF_00818	264199.stu1812	4.1e-264	916.8	Bacilli	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1TNZ6@1239,4HB24@91061,COG0165@1,COG0165@2	NA|NA|NA	E	Argininosuccinate lyase
AHPHCOMF_00819	264199.stu1813	2e-230	804.7	Bacilli	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147			iJN678.argG,iSB619.SA_RS04675	Bacteria	1TP3X@1239,4HA1E@91061,COG0137@1,COG0137@2	NA|NA|NA	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily
AHPHCOMF_00820	264199.stu1814	2.1e-282	977.6	Bacilli	gltX	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009986,GO:0030246,GO:0030247,GO:0044424,GO:0044464,GO:2001065	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016			iSB619.SA_RS02860	Bacteria	1TPJC@1239,4HAKH@91061,COG0008@1,COG0008@2	NA|NA|NA	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AHPHCOMF_00821	264199.stu1815	7.4e-80	303.1	Bacteria	amiA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	COG4166@1,COG4166@2	NA|NA|NA	E	transmembrane transport
AHPHCOMF_00822	264199.stu1816	7.3e-69	266.5	Bacteria	amiA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	COG4166@1,COG4166@2	NA|NA|NA	E	transmembrane transport
AHPHCOMF_00823	264199.stu1817	4.8e-120	437.2	Bacilli	rplA	GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113		ko:K02863	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1TPTS@1239,4HAK4@91061,COG0081@1,COG0081@2	NA|NA|NA	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
AHPHCOMF_00824	264199.stu1818	3.7e-70	270.8	Bacilli	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02867	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V1BS@1239,4HFQ0@91061,COG0080@1,COG0080@2	NA|NA|NA	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AHPHCOMF_00825	264199.stu1819	9.2e-51	206.1	Firmicutes													Bacteria	1VNK9@1239,2DSU9@1,33HF9@2	NA|NA|NA	S	Protein of unknown function (DUF3397)
AHPHCOMF_00826	264199.stu1820	2.3e-87	328.2	Bacilli	cah		4.2.1.1	ko:K01673	ko00910,map00910		R00132,R10092	RC02807	ko00000,ko00001,ko01000				Bacteria	1V0TA@1239,4HB9V@91061,COG0288@1,COG0288@2	NA|NA|NA	P	Reversible hydration of carbon dioxide
AHPHCOMF_00827	888833.HMPREF9421_0564	1.1e-57	229.2	Bacilli	WQ51_05710												Bacteria	1V6BD@1239,4HIAR@91061,COG2013@1,COG2013@2	NA|NA|NA	S	Mitochondrial biogenesis AIM24
AHPHCOMF_00828	435842.HMPREF0848_01845	6.2e-12	75.5	Bacilli	WQ51_05710												Bacteria	1V6BD@1239,4HIAR@91061,COG2013@1,COG2013@2	NA|NA|NA	S	Mitochondrial biogenesis AIM24
AHPHCOMF_00829	264199.stu1823	1.4e-226	792.0	Bacilli	radA			ko:K04485					ko00000,ko03400				Bacteria	1TQ7Y@1239,4H9YC@91061,COG1066@1,COG1066@2	NA|NA|NA	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AHPHCOMF_00830	264199.stu1824	1.1e-80	305.8	Bacilli	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23,4.1.1.36,6.3.2.5	ko:K01520,ko:K13038	ko00240,ko00770,ko00983,ko01100,map00240,map00770,map00983,map01100	M00053,M00120	R02100,R03269,R04231,R11896	RC00002,RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000,ko03400				Bacteria	1V6HX@1239,4HIZ3@91061,COG0756@1,COG0756@2	NA|NA|NA	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
AHPHCOMF_00831	264199.stu1825	1.8e-19	100.9	Bacteria	XK27_09620												Bacteria	COG0431@1,COG0431@2	NA|NA|NA	S	FMN reductase (NADPH) activity
AHPHCOMF_00832	904306.HMPREF9192_2047	4.3e-77	293.9	Firmicutes	XK27_09620												Bacteria	1V22X@1239,COG0431@1,COG0431@2	NA|NA|NA	S	reductase
AHPHCOMF_00833	264199.stu1827	2.1e-32	144.4	Bacteria	XK27_09615												Bacteria	COG0431@1,COG0431@2	NA|NA|NA	S	FMN reductase (NADPH) activity
AHPHCOMF_00834	322159.STER_1806	3.1e-115	421.0	Bacilli	XK27_09615												Bacteria	1TPRA@1239,4HDA5@91061,COG0431@1,COG0431@2,COG2461@1,COG2461@2	NA|NA|NA	C	reductase
AHPHCOMF_00835	264199.stu1830	1.6e-61	241.9	Bacilli	fnt			ko:K06212,ko:K21993					ko00000,ko02000	1.A.16.1.1,1.A.16.1.3,1.A.16.2			Bacteria	1V164@1239,4HFJC@91061,COG2116@1,COG2116@2	NA|NA|NA	P	Formate nitrite transporter
AHPHCOMF_00836	904306.HMPREF9192_2043	5.5e-64	250.4	Bacteria	XK27_08585			ko:K16926		M00582			ko00000,ko00002,ko02000	3.A.1.31			Bacteria	2BY0N@1,321KG@2	NA|NA|NA	S	Psort location CytoplasmicMembrane, score
AHPHCOMF_00837	322159.STER_1809	2e-186	658.3	Bacilli	gpsA	GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110		R00842,R00844	RC00029	ko00000,ko00001,ko01000				Bacteria	1TQ5P@1239,4HAXW@91061,COG0240@1,COG0240@2	NA|NA|NA	I	Glycerol-3-phosphate dehydrogenase
AHPHCOMF_00838	322159.STER_1810	5.1e-170	603.6	Bacilli	galU		2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQ24@1239,4HATY@91061,COG1210@1,COG1210@2	NA|NA|NA	M	UTP-glucose-1-phosphate uridylyltransferase
AHPHCOMF_00839	322159.STER_1811	5.2e-119	433.7	Bacilli	gluP		3.4.21.105	ko:K19225					ko00000,ko01000,ko01002				Bacteria	1TQXT@1239,4HCDF@91061,COG0705@1,COG0705@2	NA|NA|NA	O	membrane protein (homolog of Drosophila rhomboid)
AHPHCOMF_00840	322159.STER_1812	9.1e-95	352.8	Bacilli	ygfA	GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100		R02301	RC00183	ko00000,ko00001,ko01000			iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298	Bacteria	1VA91@1239,4HM35@91061,COG0212@1,COG0212@2	NA|NA|NA	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AHPHCOMF_00841	322159.STER_1813	7.9e-221	772.7	Bacilli	hipO	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.1.47	ko:K01436,ko:K05823,ko:K21613	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00525	R02733	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000,ko01002				Bacteria	1TPD7@1239,4H9SG@91061,COG1473@1,COG1473@2	NA|NA|NA	E	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
AHPHCOMF_00842	264199.stu1839	8.1e-59	233.8	Bacilli	dapD	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.117,2.3.1.89	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	M00016,M00525	R04364,R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000			iSbBS512_1146.SbBS512_E0158,iYO844.BSU14180	Bacteria	1TQUJ@1239,4H9KY@91061,COG2171@1,COG2171@2	NA|NA|NA	E	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
AHPHCOMF_00843	264199.stu1840	2.7e-48	197.6	Bacteria				ko:K07025					ko00000				Bacteria	COG0546@1,COG0546@2	NA|NA|NA	S	glycolate biosynthetic process
AHPHCOMF_00844	264199.stu1841	3.4e-64	250.8	Bacteria				ko:K07025					ko00000				Bacteria	COG1011@1,COG1011@2	NA|NA|NA	S	phosphatase activity
AHPHCOMF_00845	322159.STER_1816	6.3e-159	566.6	Bacteria	rrmA		2.1.1.187	ko:K00563,ko:K10947			R07233	RC00003	ko00000,ko01000,ko03000,ko03009				Bacteria	COG0500@1,COG2226@2	NA|NA|NA	Q	methyltransferase
AHPHCOMF_00848	322159.STER_1819	1.2e-91	342.4	Bacilli	tadA		3.5.4.1,3.5.4.33	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100		R00974,R01411,R02922,R10223	RC00074,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016				Bacteria	1V3HZ@1239,4HH7S@91061,COG0590@1,COG0590@2	NA|NA|NA	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
AHPHCOMF_00849	322159.STER_1821	5.1e-66	256.9	Bacilli	ssb_2			ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440				ko00000,ko00001,ko03029,ko03032,ko03400				Bacteria	1VXMZ@1239,4HXCW@91061,COG0629@1,COG0629@2	NA|NA|NA	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
AHPHCOMF_00850	322159.STER_1822	4.1e-36	156.8	Bacteria	yeeD	GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008		ko:K07112					ko00000				Bacteria	COG0425@1,COG0425@2	NA|NA|NA	O	sulfur carrier activity
AHPHCOMF_00851	264199.stu1847	1.3e-190	672.2	Bacilli	yeeE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K07112					ko00000				Bacteria	1TSNG@1239,4HDN0@91061,COG2391@1,COG2391@2	NA|NA|NA	S	Sulphur transport
AHPHCOMF_00852	264199.stu1848	7.9e-114	416.4	Bacilli	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890,ko:K06878	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1V7QA@1239,4HJBD@91061,COG0073@1,COG0073@2	NA|NA|NA	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AHPHCOMF_00853	264199.stu1849	4.2e-55	220.3	Bacilli	ytpP	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	2.7.1.180,5.3.4.1	ko:K01829,ko:K03671,ko:K03734,ko:K06196	ko04621,ko05418,map04621,map05418				ko00000,ko00001,ko01000,ko02000,ko03110	5.A.1.2			Bacteria	1VAS6@1239,4HKGM@91061,COG0526@1,COG0526@2	NA|NA|NA	CO	Thioredoxin
AHPHCOMF_00854	1035184.HMPREF1042_1989	4.1e-09	67.4	Streptococcus anginosus group													Bacteria	1TVXJ@1239,2BV7J@1,32QM1@2,42EDG@671232,4I4JA@91061	NA|NA|NA	S	Domain of unknown function (DUF4651)
AHPHCOMF_00855	322159.STER_1827	2e-205	721.5	Bacilli	pepA		3.4.11.7	ko:K01261,ko:K01269					ko00000,ko01000,ko01002				Bacteria	1TNZT@1239,4H9SM@91061,COG1363@1,COG1363@2	NA|NA|NA	G	COG1363 Cellulase M and related proteins
AHPHCOMF_00856	264199.stu1852	1.5e-130	472.2	Bacilli	proC		1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP1E@1239,4HCBY@91061,COG0345@1,COG0345@2	NA|NA|NA	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AHPHCOMF_00857	322159.STER_1829	1.8e-111	408.7	Bacilli				ko:K07052					ko00000				Bacteria	1VEE2@1239,4HP4A@91061,COG1266@1,COG1266@2	NA|NA|NA	S	CAAX amino terminal protease family protein
AHPHCOMF_00859	264199.stu1855	5e-67	260.4	Bacteria				ko:K07052					ko00000				Bacteria	COG1266@1,COG1266@2	NA|NA|NA	V	CAAX protease self-immunity
AHPHCOMF_00860	1046629.Ssal_00152	1.4e-33	148.7	Bacteria				ko:K07052					ko00000				Bacteria	COG1266@1,COG1266@2	NA|NA|NA	V	CAAX protease self-immunity
AHPHCOMF_00862	264199.stu1857	2.9e-221	774.2	Bacilli	ackA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000			iNJ661.Rv0409	Bacteria	1TQ22@1239,4HA7K@91061,COG0282@1,COG0282@2	NA|NA|NA	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AHPHCOMF_00863	264199.stu1858	5.9e-177	626.7	Bacilli	ytxK		2.1.1.72	ko:K00571					ko00000,ko01000,ko02048				Bacteria	1TRIQ@1239,4H9SE@91061,COG0827@1,COG0827@2	NA|NA|NA	L	DNA methylase
AHPHCOMF_00864	1198676.SMUGS5_08910	2e-12	78.6	Bacilli	comGF			ko:K02246,ko:K02248		M00429			ko00000,ko00002,ko02044				Bacteria	1VJKM@1239,4HQDT@91061,COG4940@1,COG4940@2	NA|NA|NA	U	Putative Competence protein ComGF
AHPHCOMF_00865	322159.STER_1837	1.5e-71	275.4	Bacilli	comGF			ko:K02246,ko:K02248		M00429			ko00000,ko00002,ko02044				Bacteria	1VKRP@1239,4HR6S@91061,COG4940@1,COG4940@2	NA|NA|NA	U	Competence protein ComGF
AHPHCOMF_00866	873449.STRCR_0577	1.4e-15	88.6	Firmicutes													Bacteria	1W385@1239,2ZS6J@2,COG2165@1	NA|NA|NA	NU	Type II secretory pathway pseudopilin
AHPHCOMF_00867	264199.stu1862	1.8e-57	228.4	Bacilli	cglD			ko:K02246		M00429			ko00000,ko00002,ko02044				Bacteria	1VPGT@1239,33A38@2,4HRZ0@91061,COG2165@1	NA|NA|NA	NU	Competence protein
AHPHCOMF_00868	322159.STER_1840	8.5e-43	179.5	Bacilli	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944		ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429			ko00000,ko00001,ko00002,ko02044	3.A.15			Bacteria	1VFI9@1239,4HNNT@91061,COG4537@1,COG4537@2	NA|NA|NA	U	Required for transformation and DNA binding
AHPHCOMF_00869	264199.stu1864	3e-145	521.2	Bacilli	cglB			ko:K02244		M00429			ko00000,ko00002,ko02044	3.A.14.1			Bacteria	1U00C@1239,4HGUA@91061,COG1459@1,COG1459@2	NA|NA|NA	NU	type II secretion system
AHPHCOMF_00870	264199.stu1865	1.9e-175	621.7	Bacilli	comGA			ko:K02243		M00429			ko00000,ko00002,ko02044	3.A.14.1			Bacteria	1TPGE@1239,4HB0C@91061,COG2804@1,COG2804@2	NA|NA|NA	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AHPHCOMF_00871	264199.stu1866	2.9e-68	264.2	Bacilli													Bacteria	1VHC7@1239,4HS15@91061,COG4699@1,COG4699@2	NA|NA|NA	S	cog cog4699
AHPHCOMF_00872	322159.STER_1844	0.0	2390.9	Bacilli	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400				Bacteria	1TNYT@1239,4HA24@91061,COG0086@1,COG0086@2	NA|NA|NA	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AHPHCOMF_00873	322159.STER_1845	0.0	2301.2	Bacilli	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400				Bacteria	1TP96@1239,4H9PK@91061,COG0085@1,COG0085@2	NA|NA|NA	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AHPHCOMF_00874	264199.stu1869	0.0	1573.1	Bacilli	pbp1B		2.4.1.129,3.4.16.4	ko:K03693,ko:K05365,ko:K05366,ko:K05367,ko:K12551,ko:K12555,ko:K21464	ko00550,ko01100,ko01501,map00550,map01100,map01501		R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011		GT51		Bacteria	1TPM5@1239,4H9SA@91061,COG0744@1,COG0744@2	NA|NA|NA	M	penicillin-binding protein
AHPHCOMF_00875	264199.stu1870	1.2e-238	832.0	Bacilli	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029			iAF1260.b1637,iBWG_1329.BWG_1452,iECDH10B_1368.ECDH10B_1771,iECDH1ME8569_1439.ECDH1ME8569_1581,iECH74115_1262.ECH74115_2349,iECIAI39_1322.ECIAI39_1418,iECNA114_1301.ECNA114_1685,iECO103_1326.ECO103_1778,iECO111_1330.ECO111_2107,iECO26_1355.ECO26_2366,iECSE_1348.ECSE_1760,iECSF_1327.ECSF_1500,iECSP_1301.ECSP_2202,iECUMN_1333.ECUMN_1928,iECW_1372.ECW_m1805,iECs_1301.ECs2346,iEKO11_1354.EKO11_2137,iETEC_1333.ETEC_1672,iEcDH1_1363.EcDH1_2003,iEcE24377_1341.EcE24377A_1847,iEcHS_1320.EcHS_A1713,iEcSMS35_1347.EcSMS35_1562,iEcolC_1368.EcolC_1992,iJO1366.b1637,iSFV_1184.SFV_1654,iSF_1195.SF1662,iSSON_1240.SSON_1519,iSbBS512_1146.SbBS512_E1829,iUMNK88_1353.UMNK88_2097,iWFL_1372.ECW_m1805,iY75_1357.Y75_RS08585	Bacteria	1TPGN@1239,4H9YV@91061,COG0162@1,COG0162@2	NA|NA|NA	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AHPHCOMF_00876	322159.STER_1848	1.6e-196	691.8	Bacilli	ilvC		1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPI7@1239,4HADK@91061,COG0059@1,COG0059@2	NA|NA|NA	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AHPHCOMF_00877	264199.stu1872	7.7e-77	293.1	Bacilli	ilvN	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	M00019,M00570,M00582	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35			Bacteria	1V2AJ@1239,4HDY5@91061,COG0440@1,COG0440@2	NA|NA|NA	E	Acetolactate synthase
AHPHCOMF_00878	322159.STER_1850	0.0	1107.4	Bacilli	ilvB		2.2.1.6	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	M00019,M00570,M00582	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35		iYO844.BSU28310	Bacteria	1TQE8@1239,4H9VR@91061,COG0028@1,COG0028@2	NA|NA|NA	EH	Acetolactate synthase
AHPHCOMF_00879	322159.STER_1851	8.8e-281	972.2	Bacilli	ilvD		4.2.1.9	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	M00019,M00570,M00582	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35		iAF987.Gmet_1259	Bacteria	1TP1R@1239,4H9ZG@91061,COG0129@1,COG0129@2	NA|NA|NA	E	Belongs to the IlvD Edd family
AHPHCOMF_00880	322159.STER_1851	8.4e-09	65.5	Bacilli	ilvD		4.2.1.9	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	M00019,M00570,M00582	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35		iAF987.Gmet_1259	Bacteria	1TP1R@1239,4H9ZG@91061,COG0129@1,COG0129@2	NA|NA|NA	E	Belongs to the IlvD Edd family
AHPHCOMF_00881	322159.STER_1854	1.7e-304	1051.2	Bacilli	yloV			ko:K07030					ko00000				Bacteria	1TQMX@1239,4HBSE@91061,COG1461@1,COG1461@2	NA|NA|NA	S	kinase related to dihydroxyacetone kinase
AHPHCOMF_00882	264199.stu1876	1.4e-57	228.8	Bacilli	asp												Bacteria	1V3Q6@1239,4HHYJ@91061,COG1302@1,COG1302@2	NA|NA|NA	S	cog cog1302
AHPHCOMF_00883	322159.STER_1856	9.3e-226	789.3	Bacilli	norN			ko:K03327					ko00000,ko02000	2.A.66.1			Bacteria	1TQMT@1239,4H9Y2@91061,COG0534@1,COG0534@2	NA|NA|NA	V	Mate efflux family protein
AHPHCOMF_00884	322159.STER_1857	2.4e-278	964.1	Bacilli	thrC		4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000			iHN637.CLJU_RS16355,iIT341.HP0098	Bacteria	1TPR0@1239,4H9R7@91061,COG0498@1,COG0498@2	NA|NA|NA	E	Threonine synthase
AHPHCOMF_00885	904306.HMPREF9192_1994	5.5e-65	253.4	Bacilli	adhE		1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220		R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000			iSB619.SA_RS00885	Bacteria	1TPB4@1239,4HAN8@91061,COG1012@1,COG1012@2,COG1454@1,COG1454@2	NA|NA|NA	C	belongs to the iron- containing alcohol dehydrogenase family
AHPHCOMF_00886	264199.stu1880	8e-35	152.5	Bacteria	adhE		1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220		R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000			iSB619.SA_RS00885	Bacteria	COG1454@1,COG1454@2	NA|NA|NA	C	hydroxyacid-oxoacid transhydrogenase activity
AHPHCOMF_00887	264199.stu1881	3.3e-65	254.2	Bacilli	adhE		1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220		R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000			iSB619.SA_RS00885	Bacteria	1TPB4@1239,4HAN8@91061,COG1454@1,COG1454@2	NA|NA|NA	C	belongs to the iron- containing alcohol dehydrogenase family
AHPHCOMF_00888	904306.HMPREF9192_1994	6.3e-132	476.9	Bacilli	adhE		1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220		R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000			iSB619.SA_RS00885	Bacteria	1TPB4@1239,4HAN8@91061,COG1012@1,COG1012@2,COG1454@1,COG1454@2	NA|NA|NA	C	belongs to the iron- containing alcohol dehydrogenase family
AHPHCOMF_00889	264199.stu1884	1.4e-63	248.8	Bacilli	adhE		1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220		R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000			iSB619.SA_RS00885	Bacteria	1UHQT@1239,4IS6J@91061,COG1012@1,COG1012@2	NA|NA|NA	C	Dehydrogenase
AHPHCOMF_00890	264199.stu1885	0.0	1291.6	Bacilli	pepO		3.4.24.71	ko:K01415,ko:K07386					ko00000,ko01000,ko01002,ko04147				Bacteria	1TQTA@1239,4HDSF@91061,COG3590@1,COG3590@2	NA|NA|NA	O	Peptidase family M13
AHPHCOMF_00891	264199.stu1886	2.8e-38	164.1	Bacilli	treC	GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005991,GO:0005993,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008788,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0015927,GO:0016052,GO:0016787,GO:0016798,GO:0033554,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046352,GO:0050896,GO:0051716,GO:0071704,GO:1901575	3.2.1.93	ko:K01226	ko00500,map00500		R00837,R06113	RC00049	ko00000,ko00001,ko01000		GH13	iECW_1372.ECW_m4600,iEKO11_1354.EKO11_4072,iEcE24377_1341.EcE24377A_4811,iEcSMS35_1347.EcSMS35_4720,iWFL_1372.ECW_m4600	Bacteria	1TP53@1239,4HA1G@91061,COG0366@1,COG0366@2	NA|NA|NA	G	COG0366 Glycosidases
AHPHCOMF_00892	264199.stu1886	1.2e-69	269.2	Bacilli	treC	GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005991,GO:0005993,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008788,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0015927,GO:0016052,GO:0016787,GO:0016798,GO:0033554,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046352,GO:0050896,GO:0051716,GO:0071704,GO:1901575	3.2.1.93	ko:K01226	ko00500,map00500		R00837,R06113	RC00049	ko00000,ko00001,ko01000		GH13	iECW_1372.ECW_m4600,iEKO11_1354.EKO11_4072,iEcE24377_1341.EcE24377A_4811,iEcSMS35_1347.EcSMS35_4720,iWFL_1372.ECW_m4600	Bacteria	1TP53@1239,4HA1G@91061,COG0366@1,COG0366@2	NA|NA|NA	G	COG0366 Glycosidases
AHPHCOMF_00893	264199.stu1887	5.9e-66	256.5	Bacilli	treC	GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005991,GO:0005993,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008788,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0015927,GO:0016052,GO:0016787,GO:0016798,GO:0033554,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046352,GO:0050896,GO:0051716,GO:0071704,GO:1901575	3.2.1.93	ko:K01226	ko00500,map00500		R00837,R06113	RC00049	ko00000,ko00001,ko01000		GH13	iECW_1372.ECW_m4600,iEKO11_1354.EKO11_4072,iEcE24377_1341.EcE24377A_4811,iEcSMS35_1347.EcSMS35_4720,iWFL_1372.ECW_m4600	Bacteria	1TP53@1239,4HA1G@91061,COG0366@1,COG0366@2	NA|NA|NA	G	COG0366 Glycosidases
AHPHCOMF_00894	264199.stu1890	1.4e-54	218.8	Bacteria	treB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0015766,GO:0015771,GO:0015772,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090589	2.7.1.201	ko:K02817,ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	M00270	R02780	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.13,4.A.1.2.4,4.A.1.2.8		iECABU_c1320.ECABU_c48060,ic_1306.c5339	Bacteria	COG1263@1,COG1263@2	NA|NA|NA	G	PTS System
AHPHCOMF_00895	264199.stu1892	5.8e-21	105.9	Bacteria	treR			ko:K03486,ko:K03710					ko00000,ko03000				Bacteria	COG2188@1,COG2188@2	NA|NA|NA	K	DNA-binding transcription factor activity
AHPHCOMF_00896	264199.stu1893	1.2e-85	322.4	Bacilli	treR			ko:K03486,ko:K03710					ko00000,ko03000				Bacteria	1TRF6@1239,4HDCX@91061,COG2188@1,COG2188@2	NA|NA|NA	K	trehalose operon
AHPHCOMF_00897	322159.STER_1865	3.3e-95	354.4	Bacilli	ywlG												Bacteria	1V3H0@1239,4HH6F@91061,COG4475@1,COG4475@2	NA|NA|NA	S	Belongs to the UPF0340 family
AHPHCOMF_00900	1046629.Ssal_02110	2e-35	154.8	Bacilli													Bacteria	1TRSF@1239,4HDM3@91061,COG2826@1,COG2826@2	NA|NA|NA	L	PFAM Integrase, catalytic core
AHPHCOMF_00901	1046629.Ssal_02110	8e-96	356.7	Bacilli													Bacteria	1TRSF@1239,4HDM3@91061,COG2826@1,COG2826@2	NA|NA|NA	L	PFAM Integrase, catalytic core
AHPHCOMF_00902	264199.stu1899	9e-164	582.8	Bacilli	fba		4.1.2.13,4.1.2.29	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568,R05378	RC00438,RC00439,RC00603,RC00604,RC00721	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQ01@1239,4H9ZU@91061,COG0191@1,COG0191@2	NA|NA|NA	G	aldolase
AHPHCOMF_00904	264199.stu1900	8.8e-110	402.9	Bacteria			6.3.2.2	ko:K01919,ko:K06048	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000				Bacteria	COG3572@1,COG3572@2	NA|NA|NA	H	ergothioneine biosynthetic process
AHPHCOMF_00905	1046629.Ssal_00112	1.5e-65	255.4	Bacilli			6.3.2.2	ko:K01919,ko:K06048	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000				Bacteria	1TW3D@1239,4HTV4@91061,COG3572@1,COG3572@2	NA|NA|NA	H	gamma-glutamylcysteine synthetase
AHPHCOMF_00906	904306.HMPREF9192_1984	2.2e-12	77.4	Bacilli			6.3.2.2	ko:K01919,ko:K06048	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000				Bacteria	1TW3D@1239,4HTV4@91061,COG3572@1,COG3572@2	NA|NA|NA	H	gamma-glutamylcysteine synthetase
AHPHCOMF_00907	1046629.Ssal_00544	3.3e-09	66.6	Bacilli													Bacteria	1TRSF@1239,4HDM3@91061,COG2826@1,COG2826@2	NA|NA|NA	L	PFAM Integrase, catalytic core
AHPHCOMF_00908	1046629.Ssal_02110	1.8e-111	408.7	Bacilli													Bacteria	1TRSF@1239,4HDM3@91061,COG2826@1,COG2826@2	NA|NA|NA	L	PFAM Integrase, catalytic core
AHPHCOMF_00909	264199.stu1907	7.4e-62	243.0	Bacilli	rplQ	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02879,ko:K16193	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V6JQ@1239,4HGX2@91061,COG0203@1,COG0203@2	NA|NA|NA	J	ribosomal protein l17
AHPHCOMF_00910	264199.stu1908	4.8e-171	607.1	Bacilli	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400				Bacteria	1TPR8@1239,4H9R1@91061,COG0202@1,COG0202@2	NA|NA|NA	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AHPHCOMF_00911	1214166.ALLG01000006_gene1437	9.6e-62	242.7	Streptococcus suis	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02948	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V3IK@1239,1WTHI@1307,4HH2T@91061,COG0100@1,COG0100@2	NA|NA|NA	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AHPHCOMF_00912	1046629.Ssal_00108	4e-57	227.3	Bacilli	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02952	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V3JH@1239,4HGX6@91061,COG0099@1,COG0099@2	NA|NA|NA	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AHPHCOMF_00913	1123301.KB904201_gene1724	6e-15	85.5	Bacteria	rpmJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02919	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	COG0257@1,COG0257@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL36 family
AHPHCOMF_00914	1123298.KB904065_gene2021	2.7e-32	144.1	Bacilli	infA	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009986,GO:0016020,GO:0030246,GO:0030247,GO:0030312,GO:0040007,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071944,GO:2001065		ko:K02518					ko00000,ko03012				Bacteria	1V9ZK@1239,4HKF4@91061,COG0361@1,COG0361@2	NA|NA|NA	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AHPHCOMF_00915	264199.stu1913	9.2e-121	439.5	Bacilli	adk	GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147			iHN637.CLJU_RS20110	Bacteria	1TP27@1239,4HA89@91061,COG0563@1,COG0563@2	NA|NA|NA	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
AHPHCOMF_00916	322159.STER_1887	9.6e-231	805.8	Bacilli	secY	GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0040007,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680		ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	3.A.5			Bacteria	1TPHB@1239,4HAWH@91061,COG0201@1,COG0201@2	NA|NA|NA	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
AHPHCOMF_00917	322159.STER_1888	4.4e-58	230.7	Bacilli	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02876	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V3KE@1239,4HFPW@91061,COG0200@1,COG0200@2	NA|NA|NA	J	binds to the 23S rRNA
AHPHCOMF_00918	264199.stu1916	2.5e-23	114.0	Bacilli	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904		ko:K02907	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1VEG4@1239,4HNHF@91061,COG1841@1,COG1841@2	NA|NA|NA	J	ribosomal protein l30
AHPHCOMF_00919	264199.stu1917	1.7e-79	302.0	Bacilli	rpsE	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904		ko:K02988	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V1B1@1239,4HFN4@91061,COG0098@1,COG0098@2	NA|NA|NA	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AHPHCOMF_00920	264199.stu1918	1.9e-56	224.9	Bacilli	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02881	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V6DM@1239,4HIGF@91061,COG0256@1,COG0256@2	NA|NA|NA	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AHPHCOMF_00921	264199.stu1919	2.3e-93	348.2	Bacilli	rplF	GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02933	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V1FC@1239,4HFQD@91061,COG0097@1,COG0097@2	NA|NA|NA	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AHPHCOMF_00922	1123304.AQYA01000030_gene1163	1.2e-67	262.3	Bacilli	rpsH	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010608,GO:0015935,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031329,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043487,GO:0043488,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903311,GO:1990904		ko:K02994	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V3KK@1239,4HH32@91061,COG0096@1,COG0096@2	NA|NA|NA	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AHPHCOMF_00923	322159.STER_1894	1.5e-28	131.3	Firmicutes	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02954	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1VEF6@1239,COG0199@1,COG0199@2	NA|NA|NA	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AHPHCOMF_00924	1046629.Ssal_00096	1.6e-94	352.1	Bacilli	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02931	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1TPE0@1239,4HBAX@91061,COG0094@1,COG0094@2	NA|NA|NA	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AHPHCOMF_00925	1046629.Ssal_00095	1.4e-47	195.3	Bacilli	rplX	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02895	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V9ZQ@1239,4HKH9@91061,COG0198@1,COG0198@2	NA|NA|NA	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AHPHCOMF_00926	264199.stu1924	1.1e-59	235.7	Bacilli	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02874	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V3N0@1239,4HGYR@91061,COG0093@1,COG0093@2	NA|NA|NA	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AHPHCOMF_00927	1046629.Ssal_00093	6e-39	166.4	Bacilli	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02961	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V9YC@1239,4HKDN@91061,COG0186@1,COG0186@2	NA|NA|NA	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AHPHCOMF_00928	264199.stu1926	2.7e-26	124.0	Bacilli	rpmC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02904	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1VEME@1239,4HNUP@91061,COG0255@1,COG0255@2	NA|NA|NA	J	Belongs to the universal ribosomal protein uL29 family
AHPHCOMF_00929	322159.STER_1900	7.2e-71	273.1	Bacilli	rplP	GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02878	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V1AY@1239,4HFPN@91061,COG0197@1,COG0197@2	NA|NA|NA	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AHPHCOMF_00930	322159.STER_1901	2.1e-117	428.3	Bacilli	rpsC	GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02982	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1TPCP@1239,4HAUR@91061,COG0092@1,COG0092@2	NA|NA|NA	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AHPHCOMF_00931	1046629.Ssal_00089	7.3e-53	213.0	Bacilli	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02890	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V6PU@1239,4HIK2@91061,COG0091@1,COG0091@2	NA|NA|NA	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AHPHCOMF_00932	322159.STER_1903	4.9e-47	193.4	Bacilli	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02965	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V6CX@1239,4HIG0@91061,COG0185@1,COG0185@2	NA|NA|NA	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AHPHCOMF_00933	264199.stu1931	8.8e-153	546.2	Bacilli	rplB	GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02886	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1TP9X@1239,4HAE8@91061,COG0090@1,COG0090@2	NA|NA|NA	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AHPHCOMF_00934	264199.stu1932	2.4e-44	184.5	Bacilli	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02892	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1VA4W@1239,4HKCV@91061,COG0089@1,COG0089@2	NA|NA|NA	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
AHPHCOMF_00935	1046629.Ssal_00085	5.7e-104	383.6	Bacilli	rplD	GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030312,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141		ko:K02926,ko:K16193	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1TPGW@1239,4HB01@91061,COG0088@1,COG0088@2	NA|NA|NA	J	Forms part of the polypeptide exit tunnel
AHPHCOMF_00936	322159.STER_1907	1.1e-110	406.0	Bacilli	rplC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234		ko:K02906	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1TPFT@1239,4HAEN@91061,COG0087@1,COG0087@2	NA|NA|NA	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AHPHCOMF_00937	322159.STER_1908	1.3e-48	198.7	Bacilli	rpsJ	GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141		ko:K02946	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V6C9@1239,4HIKH@91061,COG0051@1,COG0051@2	NA|NA|NA	J	Involved in the binding of tRNA to the ribosomes
AHPHCOMF_00938	264199.stu1936	7.8e-188	662.9	Bacilli	ruvB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	3.6.4.12	ko:K03551	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1TR47@1239,4HBMW@91061,COG2255@1,COG2255@2	NA|NA|NA	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
AHPHCOMF_00939	322159.STER_1910	0.0	1161.4	Bacilli	XK27_09800												Bacteria	1U6DU@1239,4H9XT@91061,COG1835@1,COG1835@2	NA|NA|NA	I	Acyltransferase
AHPHCOMF_00940	264199.stu1938	1.7e-35	155.6	Firmicutes	XK27_09805												Bacteria	1TRNW@1239,COG4642@1,COG4642@2	NA|NA|NA	S	MORN repeat protein
AHPHCOMF_00941	322159.STER_1912	1e-80	305.8	Bacilli	ptpA		3.1.3.48	ko:K01104,ko:K20945	ko05111,map05111				ko00000,ko00001,ko01000				Bacteria	1V6SG@1239,4HIZN@91061,COG0394@1,COG0394@2	NA|NA|NA	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AHPHCOMF_00942	322159.STER_1913	4.1e-250	870.2	Bacilli	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQ4C@1239,4H9YT@91061,COG0104@1,COG0104@2	NA|NA|NA	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AHPHCOMF_00943	1046629.Ssal_00076	1.5e-89	335.5	Bacilli	adk		2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1V7AW@1239,4HH8A@91061,COG0563@1,COG0563@2	NA|NA|NA	F	topology modulation protein
AHPHCOMF_00944	1114965.Spaf_1873	2.7e-12	77.4	Bacilli	Z012_04635			ko:K18830					ko00000,ko02048,ko03000				Bacteria	1UZI0@1239,4HC2C@91061,COG1396@1,COG1396@2	NA|NA|NA	K	Transcriptional activator, Rgg GadR MutR family
AHPHCOMF_00945	264199.stu1950	1.4e-127	462.2	Bacteria	Z012_04635												Bacteria	COG1396@1,COG1396@2	NA|NA|NA	K	sequence-specific DNA binding
AHPHCOMF_00947	264199.stu1951	6.3e-16	89.0	Firmicutes				ko:K06871					ko00000				Bacteria	1V5NX@1239,COG0641@1,COG0641@2	NA|NA|NA	C	Radical SAM
AHPHCOMF_00948	264199.stu1951	3.4e-191	674.1	Firmicutes				ko:K06871					ko00000				Bacteria	1V5NX@1239,COG0641@1,COG0641@2	NA|NA|NA	C	Radical SAM
AHPHCOMF_00949	264199.stu1952	3.9e-287	993.4	Bacilli				ko:K02068,ko:K06148		M00211			ko00000,ko00002,ko02000	3.A.1			Bacteria	1VRZB@1239,4HV44@91061,COG1132@1,COG1132@2	NA|NA|NA	V	ABC transporter transmembrane region
AHPHCOMF_00950	322159.STER_1926	2.5e-89	334.7	Bacteria													Bacteria	COG1476@1,COG1476@2	NA|NA|NA	K	sequence-specific DNA binding
AHPHCOMF_00951	1403946.Q615_SPAC00126G0051	1.3e-36	159.1	Streptococcus anginosus group				ko:K07467					ko00000				Bacteria	1VMP1@1239,42EH0@671232,4HSQH@91061,COG2946@1,COG2946@2	NA|NA|NA	L	Replication initiation factor
AHPHCOMF_00952	1403946.Q615_SPAC00126G0051	1.6e-106	392.1	Streptococcus anginosus group				ko:K07467					ko00000				Bacteria	1VMP1@1239,42EH0@671232,4HSQH@91061,COG2946@1,COG2946@2	NA|NA|NA	L	Replication initiation factor
AHPHCOMF_00953	585204.SMSK597_1426	1.9e-18	97.8	Streptococcus mitis													Bacteria	1W5B5@1239,28YJG@1,2TQ3X@28037,2ZKDA@2,4I02K@91061	NA|NA|NA	S	Domain of unknown function (DUF3173)
AHPHCOMF_00954	322159.STER_1932	1.3e-215	755.4	Bacilli	int												Bacteria	1VTS1@1239,4HU1E@91061,COG0582@1,COG0582@2	NA|NA|NA	L	Belongs to the 'phage' integrase family
AHPHCOMF_00956	264199.stu1957	5.2e-237	826.6	Bacilli	rarA			ko:K07478					ko00000				Bacteria	1TPVV@1239,4HAIS@91061,COG2256@1,COG2256@2	NA|NA|NA	L	ATPase related to the helicase subunit of the Holliday junction resolvase
AHPHCOMF_00957	264199.stu1958	8.4e-27	125.6	Bacilli	rpmB	GO:0003674,GO:0003735,GO:0005198		ko:K02902	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1VEI2@1239,4HNIK@91061,COG0227@1,COG0227@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL28 family
AHPHCOMF_00958	322159.STER_1937	2.8e-44	184.1	Bacilli	yrzL												Bacteria	1VAC4@1239,4HKD0@91061,COG4472@1,COG4472@2	NA|NA|NA	S	Belongs to the UPF0297 family
AHPHCOMF_00959	322159.STER_1938	1.2e-70	272.3	Bacilli	yqgF	GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360		ko:K07447					ko00000,ko01000				Bacteria	1V6ER@1239,4HH04@91061,COG0816@1,COG0816@2	NA|NA|NA	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AHPHCOMF_00960	322159.STER_1939	4.2e-44	183.7	Bacilli	yrzB												Bacteria	1VAPW@1239,4HKV7@91061,COG3906@1,COG3906@2	NA|NA|NA	S	Belongs to the UPF0473 family
AHPHCOMF_00961	322159.STER_1941	2.3e-301	1040.8	Bacilli	ccs												Bacteria	1V9D8@1239,2F2IJ@1,33VFI@2,4HS77@91061	NA|NA|NA	S	the current gene model (or a revised gene model) may contain a frame shift
AHPHCOMF_00962	322159.STER_1942	0.0	1507.3	Bacilli	nrdD	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0017076,GO:0018130,GO:0019001,GO:0019103,GO:0019438,GO:0019637,GO:0019692,GO:0030554,GO:0031250,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032556,GO:0032558,GO:0032559,GO:0032560,GO:0032564,GO:0032567,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0046872,GO:0046914,GO:0051065,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000			iECIAI39_1322.ECIAI39_4713,iPC815.YPO3454	Bacteria	1TR9K@1239,4HBIY@91061,COG1327@1,COG1327@2,COG1328@1,COG1328@2	NA|NA|NA	F	Ribonucleoside-triphosphate reductase
AHPHCOMF_00963	435842.HMPREF0848_01736	7.5e-14	82.0	Bacilli													Bacteria	1TXD1@1239,2DEKJ@1,2ZNBP@2,4HZYT@91061	NA|NA|NA		
AHPHCOMF_00964	322159.STER_1944	2.6e-91	341.3	Bacilli	XK27_10930												Bacteria	1V1C4@1239,4HG6C@91061,COG3981@1,COG3981@2	NA|NA|NA	K	acetyltransferase
AHPHCOMF_00965	322159.STER_1945	3.7e-116	424.1	Bacilli	nrdG	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0031250,GO:0032991,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576	1.97.1.4	ko:K04068			R04710		ko00000,ko01000			iE2348C_1286.E2348C_4563	Bacteria	1V1HG@1239,4HGJ9@91061,COG0602@1,COG0602@2	NA|NA|NA	O	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AHPHCOMF_00966	322159.STER_1946	7e-147	526.6	Bacilli	yaaA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700		ko:K09861					ko00000				Bacteria	1TR33@1239,4HFN2@91061,COG3022@1,COG3022@2	NA|NA|NA	S	Belongs to the UPF0246 family
AHPHCOMF_00967	322159.STER_1947	9.9e-169	599.4	Bacilli	XK27_01785												Bacteria	1TRBT@1239,4HBPR@91061,COG1284@1,COG1284@2	NA|NA|NA	S	cog cog1284
AHPHCOMF_00968	322159.STER_1948	0.0	1149.4	Bacilli	aspS		6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029				Bacteria	1TPCN@1239,4HACD@91061,COG0173@1,COG0173@2	NA|NA|NA	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
AHPHCOMF_00970	322159.STER_1950	1.6e-241	841.6	Bacilli	hisS		6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1TP3D@1239,4HAM2@91061,COG0124@1,COG0124@2	NA|NA|NA	J	histidyl-tRNA synthetase
AHPHCOMF_00971	1046629.Ssal_00053	5.7e-52	209.9	Bacilli	metE		2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPDQ@1239,4HADW@91061,COG0620@1,COG0620@2	NA|NA|NA	E	Methionine synthase
AHPHCOMF_00972	1046629.Ssal_00053	7.6e-64	249.6	Bacilli	metE		2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPDQ@1239,4HADW@91061,COG0620@1,COG0620@2	NA|NA|NA	E	Methionine synthase
AHPHCOMF_00973	1046629.Ssal_00053	9.2e-36	155.6	Bacilli	metE		2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPDQ@1239,4HADW@91061,COG0620@1,COG0620@2	NA|NA|NA	E	Methionine synthase
AHPHCOMF_00974	1123315.AUIP01000010_gene919	2e-25	120.9	Bacilli	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904		ko:K02911	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011,ko03029				Bacteria	1VKMZ@1239,4HR2Q@91061,COG0333@1,COG0333@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL32 family
AHPHCOMF_00975	1046629.Ssal_00051	6.7e-19	99.0	Bacteria	rpmG	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02913	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	COG0267@1,COG0267@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL33 family
AHPHCOMF_00977	264199.stu1979	3.1e-20	103.6	Bacteria	yegS	GO:0001727,GO:0003674,GO:0003824,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0030258,GO:0044237,GO:0044238,GO:0044255,GO:0046834,GO:0071704	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110		R02240	RC00002,RC00017	ko00000,ko00001,ko01000				Bacteria	COG1597@1,COG1597@2	NA|NA|NA	I	lipid kinase activity
AHPHCOMF_00978	264199.stu1980	2.7e-95	354.8	Firmicutes													Bacteria	1TRFZ@1239,COG1808@1,COG1808@2	NA|NA|NA	S	Hydrophobic domain protein
AHPHCOMF_00980	322159.STER_1959	3.7e-27	127.1	Bacilli													Bacteria	1VENK@1239,4HNKV@91061,COG2261@1,COG2261@2	NA|NA|NA	S	Membrane
AHPHCOMF_00981	322159.STER_1960	3.1e-101	374.4	Bacilli													Bacteria	1VK2R@1239,2ED8H@1,33752@2,4HQ99@91061	NA|NA|NA		
AHPHCOMF_00982	264199.stu1984	1.8e-23	114.4	Bacteria													Bacteria	COG5547@1,COG5547@2	NA|NA|NA	S	Small integral membrane protein
AHPHCOMF_00983	264199.stu1986	1.2e-71	276.2	Bacteria													Bacteria	COG1302@1,COG1302@2	NA|NA|NA	M	Protein conserved in bacteria
AHPHCOMF_00984	322159.STER_1963	4.9e-12	76.6	Bacteria													Bacteria	COG3237@1,COG3237@2	NA|NA|NA	K	CsbD-like
AHPHCOMF_00985	1046629.Ssal_00748	1e-33	149.4	Bacilli													Bacteria	1TPFS@1239,4H9V9@91061,COG3039@1,COG3039@2	NA|NA|NA	L	Transposase
AHPHCOMF_00986	888049.HMPREF8578_0092	7.6e-22	109.8	Streptococcus oralis													Bacteria	1VFJD@1239,1WPW6@1303,2E660@1,330UP@2,4I5SW@91061	NA|NA|NA		
AHPHCOMF_00987	1005705.HMPREF9967_0010	1.3e-84	319.3	Streptococcus infantis													Bacteria	1TQWX@1239,43F6C@68892,4HY19@91061,COG2932@1,COG2932@2	NA|NA|NA	K	Peptidase S24-like
AHPHCOMF_00988	1114965.Spaf_1858	2.1e-08	63.5	Bacilli													Bacteria	1TQWX@1239,4HY19@91061,COG2932@1,COG2932@2	NA|NA|NA	K	Peptidase S24-like protein
AHPHCOMF_00989	435842.HMPREF0848_01229	2.3e-55	221.5	Bacilli													Bacteria	1VPKW@1239,4HZKQ@91061,COG2856@1,COG2856@2	NA|NA|NA	E	IrrE N-terminal-like domain
AHPHCOMF_00990	435842.HMPREF0848_01229	8e-49	199.5	Bacilli													Bacteria	1VPKW@1239,4HZKQ@91061,COG2856@1,COG2856@2	NA|NA|NA	E	IrrE N-terminal-like domain
AHPHCOMF_00991	1116231.SMA_1382	2e-103	381.7	Bacilli													Bacteria	1TP4C@1239,4HAXJ@91061,COG3328@1,COG3328@2	NA|NA|NA	L	Transposase
AHPHCOMF_00992	1116231.SMA_0321	6.6e-37	159.5	Bacilli													Bacteria	1TP4C@1239,4HAXJ@91061,COG3328@1,COG3328@2	NA|NA|NA	L	Transposase
AHPHCOMF_00993	1116231.SMA_0321	2.4e-53	214.5	Bacilli													Bacteria	1TP4C@1239,4HAXJ@91061,COG3328@1,COG3328@2	NA|NA|NA	L	Transposase
AHPHCOMF_00994	1069533.Sinf_0805	2.3e-38	164.5	Bacteria				ko:K07483					ko00000				Bacteria	COG2963@1,COG2963@2	NA|NA|NA	L	transposase activity
AHPHCOMF_00995	272623.L0432	8.1e-154	549.7	Bacilli				ko:K07497					ko00000				Bacteria	1TU21@1239,4HDK4@91061,COG2801@1,COG2801@2	NA|NA|NA	L	COG2801 Transposase and inactivated derivatives
AHPHCOMF_00996	1002367.HMPREF0673_01304	1e-45	190.7	Bacteroidia													Bacteria	2G2GR@200643,4NW1M@976,COG0463@1,COG0463@2	NA|NA|NA	M	Glycosyltransferase family 92
AHPHCOMF_00997	1346.DQ08_00960	4.3e-61	240.4	Bacilli				ko:K07497					ko00000				Bacteria	1TU21@1239,4HDK4@91061,COG2801@1,COG2801@2	NA|NA|NA	L	COG2801 Transposase and inactivated derivatives
AHPHCOMF_00998	264199.stu1992	4.8e-106	391.0	Bacilli													Bacteria	1VGGF@1239,4I0VY@91061,COG3595@1,COG3595@2	NA|NA|NA	S	Putative adhesin
AHPHCOMF_00999	322159.STER_1969	3.9e-161	575.5	Bacilli	XK27_06930			ko:K01421					ko00000				Bacteria	1TQ15@1239,4H9T9@91061,COG1511@1,COG1511@2	NA|NA|NA	V	domain protein
AHPHCOMF_01000	264199.stu1995	1.6e-94	352.1	Bacteria	XK27_06935												Bacteria	COG1309@1,COG1309@2	NA|NA|NA	K	transcriptional regulator
AHPHCOMF_01001	322159.STER_1971	4.8e-55	220.3	Firmicutes	ypaA			ko:K08987					ko00000				Bacteria	1VAEU@1239,COG3759@1,COG3759@2	NA|NA|NA	M	Membrane
AHPHCOMF_01002	1158607.UAU_00701	2.7e-08	63.9	Enterococcaceae													Bacteria	1W3FT@1239,2914P@1,2ZNS1@2,4B40K@81852,4I23Q@91061	NA|NA|NA		
AHPHCOMF_01003	264199.stu1997	9.8e-109	399.4	Bacilli	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112		ko:K02986	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1TR0J@1239,4HAC9@91061,COG0522@1,COG0522@2	NA|NA|NA	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AHPHCOMF_01004	264199.stu1998	8.2e-48	196.1	Bacilli	veg												Bacteria	1VPZY@1239,4HSFF@91061,COG4466@1,COG4466@2	NA|NA|NA	S	Biofilm formation stimulator VEG
AHPHCOMF_01005	322159.STER_1975	1.5e-245	855.1	Bacilli	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112				ko00000,ko00001,ko01000,ko03032				Bacteria	1TPCT@1239,4H9Y8@91061,COG0305@1,COG0305@2	NA|NA|NA	L	Participates in initiation and elongation during chromosome replication
AHPHCOMF_01006	322159.STER_1976	3.9e-70	270.8	Bacilli	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02939	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V6QG@1239,4HIKJ@91061,COG0359@1,COG0359@2	NA|NA|NA	J	binds to the 23S rRNA
AHPHCOMF_01007	264199.stu2001	0.0	1257.7	Bacilli	yybT												Bacteria	1TPGP@1239,4HBVH@91061,COG3887@1,COG3887@2	NA|NA|NA	T	signaling protein consisting of a modified GGDEF domain and a DHH domain
AHPHCOMF_01008	264199.stu2002	0.0	1229.9	Bacilli	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363		ko:K03495			R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036				Bacteria	1TQ4B@1239,4HA6S@91061,COG0445@1,COG0445@2	NA|NA|NA	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
AHPHCOMF_01009	435842.HMPREF0848_01708	1.5e-77	295.4	Bacilli													Bacteria	1VAVP@1239,4HSPC@91061,COG1051@1,COG1051@2	NA|NA|NA	F	NUDIX domain
AHPHCOMF_01010	264199.stu2003	8.6e-220	769.2	Bacilli	mnmA	GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.8.1.13	ko:K00566	ko04122,map04122		R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016				Bacteria	1TPIZ@1239,4HBJ6@91061,COG0482@1,COG0482@2	NA|NA|NA	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
AHPHCOMF_01011	264199.stu2004	0.0	1098.6	Bacilli													Bacteria	1V0XZ@1239,4HEBN@91061,COG4485@1,COG4485@2	NA|NA|NA	S	Bacterial membrane protein, YfhO
AHPHCOMF_01012	264199.stu2005	1.5e-88	332.4	Bacilli	isaA			ko:K21687					ko00000		GH23		Bacteria	1VGPA@1239,4HP1I@91061,COG0741@1,COG0741@2	NA|NA|NA	M	Immunodominant staphylococcal antigen A
AHPHCOMF_01013	264199.stu2006	5.3e-85	320.5	Bacilli	lytE												Bacteria	1VA10@1239,4HMUH@91061,COG1388@1,COG1388@2	NA|NA|NA	M	LysM domain protein
AHPHCOMF_01014	264199.stu2007	2e-138	498.4	Bacilli	ecfT	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656		ko:K02008,ko:K16783,ko:K16785	ko02010,map02010	M00245,M00246,M00581,M00582			ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35			Bacteria	1TQ0E@1239,4H9VT@91061,COG0619@1,COG0619@2	NA|NA|NA	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AHPHCOMF_01015	264199.stu2008	5.2e-153	547.0	Bacilli	ecfA2	GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008144,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032217,GO:0032218,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035461,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0097159,GO:0097367,GO:0098656,GO:1901265,GO:1901363	3.6.3.55	ko:K02068,ko:K06857,ko:K16784,ko:K16786,ko:K16787	ko02010,map02010	M00186,M00211,M00581,M00582	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35,3.A.1.6.2,3.A.1.6.4			Bacteria	1TPH8@1239,4HA7T@91061,COG1122@1,COG1122@2	NA|NA|NA	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AHPHCOMF_01016	264199.stu2009	1.5e-152	545.4	Bacilli	ecfA1	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656		ko:K16784,ko:K16786,ko:K16787	ko02010,map02010	M00581,M00582			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35			Bacteria	1TPH8@1239,4H9R8@91061,COG1122@1,COG1122@2	NA|NA|NA	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AHPHCOMF_01017	264199.stu2010	3.1e-90	337.8	Bacilli	pgsA	GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100		R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000			iSB619.SA_RS06365	Bacteria	1V6PJ@1239,4HCEX@91061,COG0558@1,COG0558@2	NA|NA|NA	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AHPHCOMF_01018	322159.STER_1987	6.3e-138	496.9	Bacteria	ymfM			ko:K15539					ko00000				Bacteria	COG1426@1,COG1426@2	NA|NA|NA	S	sequence-specific DNA binding
AHPHCOMF_01019	264199.stu2012	3.1e-242	844.0	Bacilli	ymfH			ko:K07263					ko00000,ko01000,ko01002				Bacteria	1TP5I@1239,4H9YG@91061,COG0612@1,COG0612@2	NA|NA|NA	S	Peptidase M16
AHPHCOMF_01020	322159.STER_1989	1.1e-234	818.9	Bacilli	ymfF												Bacteria	1TPN6@1239,4H9P5@91061,COG0612@1,COG0612@2	NA|NA|NA	S	Peptidase M16
AHPHCOMF_01021	264199.stu2014	2.3e-44	184.9	Bacilli	yaaA	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576		ko:K14761					ko00000,ko03009				Bacteria	1VKF4@1239,4HRX5@91061,COG2501@1,COG2501@2	NA|NA|NA	S	S4 domain protein YaaA
AHPHCOMF_01022	322159.STER_1991	1.7e-204	718.4	Bacilli	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576		ko:K03629	ko03440,map03440				ko00000,ko00001,ko03400				Bacteria	1TP9U@1239,4HA0W@91061,COG1195@1,COG1195@2	NA|NA|NA	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AHPHCOMF_01023	322159.STER_1992	1.5e-275	954.9	Bacilli	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147			iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027	Bacteria	1TNZ1@1239,4H9V3@91061,COG0516@1,COG0516@2,COG0517@1,COG0517@2	NA|NA|NA	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
AHPHCOMF_01024	322159.STER_1993	8.2e-193	679.5	Bacilli	trpS	GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1TPY7@1239,4HA1K@91061,COG0180@1,COG0180@2	NA|NA|NA	J	Tryptophanyl-tRNA synthetase
AHPHCOMF_01025	322159.STER_1994	5.4e-153	547.0	Bacilli	yvjA												Bacteria	1TR9J@1239,4H9N6@91061,COG1284@1,COG1284@2	NA|NA|NA	S	membrane
AHPHCOMF_01026	264199.stu2020	6.7e-306	1055.8	Bacilli	ybiT	GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0050896		ko:K06158					ko00000,ko03012				Bacteria	1TPW0@1239,4HATH@91061,COG0488@1,COG0488@2	NA|NA|NA	S	abc transporter atp-binding protein
AHPHCOMF_01027	264199.stu2021	0.0	1656.3	Bacilli	XK27_10405												Bacteria	1TRR1@1239,4HCR9@91061,COG4485@1,COG4485@2	NA|NA|NA	S	Bacterial membrane protein YfhO
AHPHCOMF_01031	264199.stu2022	6.2e-120	436.8	Firmicutes	yoaK												Bacteria	1V1VQ@1239,COG3619@1,COG3619@2	NA|NA|NA	S	Psort location CytoplasmicMembrane, score
AHPHCOMF_01032	322159.STER_2001	1.1e-86	325.9	Bacilli	rlmH		2.1.1.177	ko:K00783					ko00000,ko01000,ko03009				Bacteria	1V3JM@1239,4HFP8@91061,COG1576@1,COG1576@2	NA|NA|NA	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AHPHCOMF_01033	264199.stu2024	5.3e-194	683.7	Bacilli	htrA	GO:0008150,GO:0009266,GO:0009628,GO:0050896	3.4.21.107	ko:K04691,ko:K04771	ko01503,ko02020,map01503,map02020	M00728			ko00000,ko00001,ko00002,ko01000,ko01002,ko03110				Bacteria	1TRM8@1239,4HA31@91061,COG0265@1,COG0265@2	NA|NA|NA	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
AHPHCOMF_01034	322159.STER_2003	8.5e-134	483.0	Bacilli	parB			ko:K03497					ko00000,ko03000,ko03036,ko04812				Bacteria	1TQ2B@1239,4H9TB@91061,COG1475@1,COG1475@2	NA|NA|NA	K	Belongs to the ParB family
AHPHCOMF_01035	264199.stu0001	1.3e-257	895.2	Bacilli	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837		ko:K02313	ko02020,ko04112,map02020,map04112				ko00000,ko00001,ko03032,ko03036				Bacteria	1TPV7@1239,4H9MW@91061,COG0593@1,COG0593@2	NA|NA|NA	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AHPHCOMF_01036	322159.STER_0002	6.3e-202	709.9	Bacilli	dnaN		2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1TQ7J@1239,4H9TF@91061,COG0592@1,COG0592@2	NA|NA|NA	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
AHPHCOMF_01037	1046629.Ssal_02164	1.1e-29	135.2	Bacilli	yyzM												Bacteria	1VEQ7@1239,4HNHU@91061,COG4481@1,COG4481@2	NA|NA|NA	S	Protein conserved in bacteria
AHPHCOMF_01038	322159.STER_0005	1.1e-203	715.7	Bacilli	ychF	GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772		ko:K06942					ko00000,ko03009				Bacteria	1TPRK@1239,4H9SQ@91061,COG0012@1,COG0012@2	NA|NA|NA	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
AHPHCOMF_01039	264199.stu0005	1.4e-104	385.6	Bacilli	pth	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101	3.1.1.29	ko:K01056					ko00000,ko01000,ko03012				Bacteria	1V3NB@1239,4HH2Z@91061,COG0193@1,COG0193@2	NA|NA|NA	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
AHPHCOMF_01040	322159.STER_0007	0.0	2267.7	Bacilli	mfd			ko:K03723	ko03420,map03420				ko00000,ko00001,ko01000,ko03400				Bacteria	1TPF1@1239,4H9NB@91061,COG1197@1,COG1197@2	NA|NA|NA	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AHPHCOMF_01041	264199.stu0007	1.7e-39	168.3	Bacilli	yabO	GO:0008150,GO:0040007											Bacteria	1VEI5@1239,4HKJJ@91061,COG1188@1,COG1188@2	NA|NA|NA	J	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
AHPHCOMF_01042	322159.STER_0009	3.5e-61	240.7	Bacilli	divIC			ko:K05589,ko:K13052					ko00000,ko03036				Bacteria	1VKC5@1239,4HR53@91061,COG2919@1,COG2919@2	NA|NA|NA	D	Septum formation initiator
AHPHCOMF_01044	322159.STER_0011	1.3e-240	838.6	Bacilli	XK27_09285		3.5.2.6	ko:K01467,ko:K17836	ko00311,ko01130,ko01501,ko02020,map00311,map01130,map01501,map02020	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504				Bacteria	1VGXR@1239,4IPWW@91061,COG2367@1,COG2367@2	NA|NA|NA	V	Beta-lactamase enzyme family
AHPHCOMF_01045	322159.STER_0012	7.2e-239	832.8	Bacilli	tilS		2.4.2.8,6.3.4.19	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110		R01132,R01229,R02142,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016				Bacteria	1TPXP@1239,4H9ZM@91061,COG0037@1,COG0037@2	NA|NA|NA	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
AHPHCOMF_01046	264199.stu0011	3.4e-97	360.9	Bacilli	hpt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.2.8,6.3.4.19	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110		R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000,ko03016				Bacteria	1V1C9@1239,4HFZ2@91061,COG0634@1,COG0634@2	NA|NA|NA	F	Belongs to the purine pyrimidine phosphoribosyltransferase family
AHPHCOMF_01047	264199.stu0012	0.0	1245.0	Bacilli	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575		ko:K03798		M00742			ko00000,ko00002,ko01000,ko01002,ko03110				Bacteria	1TPTV@1239,4HAJB@91061,COG0465@1,COG0465@2	NA|NA|NA	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AHPHCOMF_01048	322159.STER_0015	1.7e-162	578.6	Firmicutes				ko:K07485					ko00000				Bacteria	1TQ93@1239,COG3464@1,COG3464@2	NA|NA|NA	L	Transposase
AHPHCOMF_01049	322159.STER_0016	3.2e-46	190.7	Firmicutes				ko:K07483					ko00000				Bacteria	1W68S@1239,COG2963@1,COG2963@2	NA|NA|NA	L	Transposase
AHPHCOMF_01050	322159.STER_0016	2.5e-23	114.0	Firmicutes				ko:K07483					ko00000				Bacteria	1W68S@1239,COG2963@1,COG2963@2	NA|NA|NA	L	Transposase
AHPHCOMF_01051	264199.stu0018	4.2e-29	133.3	Bacteria				ko:K07497					ko00000				Bacteria	COG2801@1,COG2801@2	NA|NA|NA	L	transposition
AHPHCOMF_01064	1198676.SMUGS5_00840	5.3e-11	72.0	Firmicutes													Bacteria	1VP0T@1239,2EG8N@1,33A0G@2	NA|NA|NA		
AHPHCOMF_01070	322159.STER_0040	5.5e-139	500.4	Bacilli	mreC	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963		ko:K03570					ko00000,ko03036	9.B.157.1			Bacteria	1TR1V@1239,4HB0K@91061,COG1792@1,COG1792@2	NA|NA|NA	M	Involved in formation and maintenance of cell shape
AHPHCOMF_01071	264199.stu0021	6.3e-88	330.1	Bacteria	mreD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944		ko:K03571					ko00000,ko03036	9.B.157.1			Bacteria	COG2891@1,COG2891@2	NA|NA|NA	M	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AHPHCOMF_01072	264199.stu0022	1.7e-90	340.1	Bacilli	usp		3.5.1.28	ko:K21471,ko:K22409					ko00000,ko01000,ko01002,ko01011		CBM50		Bacteria	1VCXB@1239,4IS6H@91061,COG3883@1,COG3883@2,COG3942@1,COG3942@2	NA|NA|NA	S	CHAP domain
AHPHCOMF_01073	264199.stu0023	1.2e-174	619.0	Bacilli	prs		2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_2848	Bacteria	1TQ6Q@1239,4HB61@91061,COG0462@1,COG0462@2	NA|NA|NA	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AHPHCOMF_01074	264199.stu0026	2.9e-218	764.2	Bacilli	araT		2.6.1.1	ko:K00812,ko:K00841,ko:K10907	ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	M00525	R00355,R00694,R00734,R00896,R02433,R02619,R04467,R05052	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	1TP0J@1239,4HA13@91061,COG0436@1,COG0436@2	NA|NA|NA	E	Aminotransferase
AHPHCOMF_01075	264199.stu0027	7e-144	516.5	Bacilli	recO	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360		ko:K03584	ko03440,map03440				ko00000,ko00001,ko03400				Bacteria	1UZ19@1239,4HAHI@91061,COG1381@1,COG1381@2	NA|NA|NA	L	Involved in DNA repair and RecF pathway recombination
AHPHCOMF_01076	264199.stu0028	1.1e-176	625.9	Bacilli	plsX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	1TPXS@1239,4HA0R@91061,COG0416@1,COG0416@2	NA|NA|NA	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
AHPHCOMF_01077	322159.STER_0048	9.3e-34	149.1	Bacteria	acpP1			ko:K02078					ko00000,ko00001				Bacteria	COG0236@1,COG0236@2	NA|NA|NA	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AHPHCOMF_01078	264199.stu0030	9.9e-129	466.1	Bacilli	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016881,GO:0044424,GO:0044444,GO:0044464	4.1.1.21,4.3.2.2,6.3.2.6	ko:K01587,ko:K01756,ko:K01923	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04209,R04559,R04591	RC00064,RC00162,RC00379,RC00444,RC00445,RC00590	ko00000,ko00001,ko00002,ko01000			iAF1260.b2476,iB21_1397.B21_02330,iBWG_1329.BWG_2240,iE2348C_1286.E2348C_2713,iEC042_1314.EC042_2677,iEC55989_1330.EC55989_2759,iECABU_c1320.ECABU_c27880,iECBD_1354.ECBD_1213,iECB_1328.ECB_02368,iECDH10B_1368.ECDH10B_2642,iECDH1ME8569_1439.ECDH1ME8569_2402,iECDH1ME8569_1439.EcDH1_1193,iECD_1391.ECD_02368,iECED1_1282.ECED1_2911,iECH74115_1262.ECH74115_3698,iECIAI1_1343.ECIAI1_2527,iECNA114_1301.ECNA114_2561,iECO103_1326.ECO103_2988,iECO111_1330.ECO111_3199,iECO26_1355.ECO26_3522,iECOK1_1307.ECOK1_2784,iECP_1309.ECP_2490,iECS88_1305.ECS88_2658,iECSE_1348.ECSE_2760,iECSF_1327.ECSF_2329,iECSP_1301.ECSP_3415,iECUMN_1333.ECUMN_2789,iECW_1372.ECW_m2698,iECs_1301.ECs3338,iEKO11_1354.EKO11_1259,iETEC_1333.ETEC_2581,iEcDH1_1363.EcDH1_1193,iEcE24377_1341.EcE24377A_2757,iEcHS_1320.EcHS_A2607,iEcSMS35_1347.EcSMS35_2623,iEcolC_1368.EcolC_1200,iG2583_1286.G2583_2999,iJN746.PP_1240,iJO1366.b2476,iJR904.b2476,iLF82_1304.LF82_1775,iNRG857_1313.NRG857_12360,iSFV_1184.SFV_2521,iSF_1195.SF2519,iSFxv_1172.SFxv_2773,iS_1188.S2669,iSbBS512_1146.SbBS512_E2848,iUMNK88_1353.UMNK88_3071,iWFL_1372.ECW_m2698,iY75_1357.Y75_RS12925,iYL1228.KPN_02810,iZ_1308.Z3735	Bacteria	1TP11@1239,4H9U8@91061,COG0152@1,COG0152@2	NA|NA|NA	F	Belongs to the SAICAR synthetase family
AHPHCOMF_01079	322159.STER_0050	0.0	2419.8	Bacilli	purL		6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPAS@1239,4HB3N@91061,COG0046@1,COG0046@2,COG0047@1,COG0047@2	NA|NA|NA	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AHPHCOMF_01080	322159.STER_0051	3.8e-276	956.8	Bacilli	purF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002			iSB619.SA_RS05225	Bacteria	1TPH3@1239,4HAXU@91061,COG0034@1,COG0034@2	NA|NA|NA	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AHPHCOMF_01081	322159.STER_0052	4.8e-185	653.7	Bacilli	purM	GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.1,6.3.4.13	ko:K01933,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04208	RC00090,RC00166,RC01100	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_1844,iECSF_1327.ECSF_2340	Bacteria	1TP9J@1239,4HABW@91061,COG0150@1,COG0150@2	NA|NA|NA	F	Phosphoribosylformylglycinamidine cyclo-ligase
AHPHCOMF_01082	264199.stu0034	1.4e-101	375.6	Bacilli	purN		2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000				Bacteria	1V3RJ@1239,4HGY5@91061,COG0299@1,COG0299@2	NA|NA|NA	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AHPHCOMF_01083	322159.STER_0054	2.5e-294	1017.3	Bacilli	purH	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147			iJN678.purH	Bacteria	1TPQ5@1239,4H9YY@91061,COG0138@1,COG0138@2	NA|NA|NA	F	Bifunctional purine biosynthesis protein PurH
AHPHCOMF_01084	322159.STER_0055	1e-90	339.3	Bacteria				ko:K07483					ko00000				Bacteria	COG2963@1,COG2963@2	NA|NA|NA	L	transposase activity
AHPHCOMF_01085	264199.stu0206	3.5e-50	204.1	Bacteria				ko:K07497					ko00000				Bacteria	COG2801@1,COG2801@2	NA|NA|NA	L	transposition
AHPHCOMF_01086	1161413.HMPREF1510_1836	2e-32	144.4	Firmicutes				ko:K07497					ko00000				Bacteria	1TQQY@1239,COG2801@1,COG2801@2	NA|NA|NA	L	Integrase core domain protein
AHPHCOMF_01087	322159.STER_0057	2.3e-161	574.7	Bacilli				ko:K21471					ko00000,ko01000,ko01002,ko01011				Bacteria	1VUNU@1239,4HVY0@91061,COG3942@1,COG3942@2	NA|NA|NA	S	CHAP domain
AHPHCOMF_01088	322159.STER_0058	3.4e-241	840.5	Bacilli	purD		6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000			iSB619.SA_RS05245,iYO844.BSU06530	Bacteria	1UHN9@1239,4HA70@91061,COG0151@1,COG0151@2	NA|NA|NA	F	Belongs to the GARS family
AHPHCOMF_01089	322159.STER_0059	4.9e-76	290.4	Bacilli	purE	GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000			iETEC_1333.ETEC_0575,iJN746.PP_5336,iPC815.YPO3076,iUTI89_1310.UTI89_C0551	Bacteria	1V1MV@1239,4HFR7@91061,COG0041@1,COG0041@2	NA|NA|NA	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AHPHCOMF_01090	322159.STER_0060	2.2e-204	718.0	Bacilli	purK		6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQCD@1239,4H9M5@91061,COG0026@1,COG0026@2	NA|NA|NA	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AHPHCOMF_01091	264199.stu0043	9.2e-141	506.1	Firmicutes			1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000				Bacteria	1UD8U@1239,COG1893@1,COG1893@2	NA|NA|NA	H	Ketopantoate reductase
AHPHCOMF_01092	264199.stu0045	8.7e-248	862.4	Bacilli	purB	GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000			iLJ478.TM1095,iSB619.SA_RS09895	Bacteria	1TPMM@1239,4HACW@91061,COG0015@1,COG0015@2	NA|NA|NA	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AHPHCOMF_01093	322159.STER_0065	0.0	1106.7	Bacilli	argS		6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029				Bacteria	1TPEZ@1239,4HAR3@91061,COG0018@1,COG0018@2	NA|NA|NA	J	Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
AHPHCOMF_01094	264199.stu0048	8.2e-70	269.6	Bacilli	argR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141		ko:K03402					ko00000,ko03000				Bacteria	1V1R7@1239,4HFY8@91061,COG1438@1,COG1438@2	NA|NA|NA	K	Regulates arginine biosynthesis genes
AHPHCOMF_01095	264199.stu0049	1.5e-56	225.3	Bacilli	ymcA		3.6.3.21	ko:K02028		M00236			ko00000,ko00002,ko01000,ko02000	3.A.1.3			Bacteria	1V4W0@1239,4HH6Y@91061,COG4550@1,COG4550@2	NA|NA|NA	S	Belongs to the UPF0342 family
AHPHCOMF_01096	322159.STER_0068	0.0	1643.6	Bacilli	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391		ko:K03555	ko03430,map03430				ko00000,ko00001,ko03400				Bacteria	1TPRJ@1239,4HA63@91061,COG0249@1,COG0249@2	NA|NA|NA	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AHPHCOMF_01097	322159.STER_0069	7e-34	149.4	Bacilli													Bacteria	1VHBQ@1239,2E0UI@1,32WBZ@2,4HRYH@91061	NA|NA|NA	S	Protein of unknown function (DUF3021)
AHPHCOMF_01098	322159.STER_0070	1.2e-61	242.3	Bacteria													Bacteria	COG3279@1,COG3279@2	NA|NA|NA	KT	phosphorelay signal transduction system
AHPHCOMF_01100	322159.STER_0072	0.0	1251.1	Bacilli	mutL	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391		ko:K03572	ko03430,map03430				ko00000,ko00001,ko03400				Bacteria	1TPGK@1239,4HB34@91061,COG0323@1,COG0323@2	NA|NA|NA	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AHPHCOMF_01102	322159.STER_0074	7.8e-103	379.8	Bacilli	ruvA	GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03550	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1V3KF@1239,4HHI5@91061,COG0632@1,COG0632@2	NA|NA|NA	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
AHPHCOMF_01103	322159.STER_0075	1.9e-106	391.7	Bacilli	tag		3.2.2.20	ko:K01246	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	1V9B8@1239,4HJ4I@91061,COG2818@1,COG2818@2	NA|NA|NA	L	3-methyladenine DNA glycosylase
AHPHCOMF_01104	322159.STER_0076	3.2e-231	807.4	Bacilli	cinA	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760		R02322	RC00100	ko00000,ko00001,ko01000				Bacteria	1TQ1N@1239,4HATN@91061,COG1058@1,COG1058@2,COG1546@1,COG1546@2	NA|NA|NA	S	Belongs to the CinA family
AHPHCOMF_01105	322159.STER_0077	4.7e-205	720.3	Bacilli	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360		ko:K03553	ko03440,map03440	M00729			ko00000,ko00001,ko00002,ko03400				Bacteria	1TPD5@1239,4HAG5@91061,COG0468@1,COG0468@2	NA|NA|NA	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AHPHCOMF_01106	264199.stu0061	2.3e-66	258.1	Bacilli	spxA_2		1.20.4.1	ko:K00537,ko:K16509					ko00000,ko01000				Bacteria	1VYBB@1239,4HWYC@91061,COG1393@1,COG1393@2	NA|NA|NA	P	Belongs to the ArsC family
AHPHCOMF_01112	1198676.SMUGS5_00840	2.6e-10	69.7	Firmicutes													Bacteria	1VP0T@1239,2EG8N@1,33A0G@2	NA|NA|NA		
AHPHCOMF_01115	1123309.AQYB01000022_gene40	1.9e-07	60.1	Bacilli													Bacteria	1VNP3@1239,2ED1A@1,336Y8@2,4HRCX@91061	NA|NA|NA		
AHPHCOMF_01120	322159.STER_0095	0.0	2910.9	Bacilli	polC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.7.7	ko:K02342,ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1TPAG@1239,4H9RF@91061,COG2176@1,COG2176@2	NA|NA|NA	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AHPHCOMF_01121	264199.stu0063	1.2e-235	822.0	Bacilli	pepS			ko:K19689					ko00000,ko01000,ko01002				Bacteria	1TP65@1239,4H9W8@91061,COG2309@1,COG2309@2	NA|NA|NA	E	COG2309 Leucyl aminopeptidase (aminopeptidase T)
AHPHCOMF_01122	264199.stu0064	5.5e-36	156.4	Bacteria	XK27_02060												Bacteria	COG2261@1,COG2261@2	NA|NA|NA	S	Transglycosylase associated protein
AHPHCOMF_01123	264199.stu0065	2.6e-55	221.1	Bacteria	badR			ko:K15973					ko00000,ko03000				Bacteria	COG1846@1,COG1846@2	NA|NA|NA	K	DNA-binding transcription factor activity
AHPHCOMF_01124	264199.stu0066	3.5e-97	360.9	Firmicutes				ko:K19784					ko00000				Bacteria	1VAI8@1239,COG0431@1,COG0431@2	NA|NA|NA	S	reductase
AHPHCOMF_01125	322159.STER_0018	1e-87	329.3	Firmicutes				ko:K07497					ko00000				Bacteria	1TQQY@1239,COG2801@1,COG2801@2	NA|NA|NA	L	Integrase core domain protein
AHPHCOMF_01126	322159.STER_1759	2.3e-38	164.5	Bacteria				ko:K07497					ko00000				Bacteria	COG2801@1,COG2801@2	NA|NA|NA	L	transposition
AHPHCOMF_01127	264199.stu0071	7.3e-22	109.0	Bacteria	yocD		3.4.17.13	ko:K01297					ko00000,ko01000,ko01002,ko01011				Bacteria	COG1619@1,COG1619@2	NA|NA|NA	V	carboxypeptidase activity
AHPHCOMF_01128	1116231.SMA_2094	1.9e-86	325.1	Bacilli	yocD		3.4.17.13	ko:K01297					ko00000,ko01000,ko01002,ko01011				Bacteria	1TRBB@1239,4HB1P@91061,COG1619@1,COG1619@2	NA|NA|NA	V	proteins, homologs of microcin C7 resistance protein MccF
AHPHCOMF_01131	264199.stu0073	1.3e-137	495.7	Bacilli	rpsB	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02967	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1TPNA@1239,4H9N5@91061,COG0052@1,COG0052@2	NA|NA|NA	J	Belongs to the universal ribosomal protein uS2 family
AHPHCOMF_01132	264199.stu0074	1.7e-182	645.2	Bacilli	tsf	GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065		ko:K02357					ko00000,ko03012,ko03029				Bacteria	1TPFJ@1239,4HBDV@91061,COG0264@1,COG0264@2	NA|NA|NA	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AHPHCOMF_01133	264199.stu0075	1.1e-83	315.8	Bacilli													Bacteria	1V3UW@1239,4HPN6@91061,COG2426@1,COG2426@2	NA|NA|NA	S	Putative small multi-drug export protein
AHPHCOMF_01134	264199.stu0076	6.2e-76	290.0	Bacilli	ctsR	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170		ko:K03708					ko00000,ko03000				Bacteria	1VAXT@1239,4HIFT@91061,COG4463@1,COG4463@2	NA|NA|NA	K	Belongs to the CtsR family
AHPHCOMF_01135	264199.stu0077	0.0	1556.6	Bacilli	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170		ko:K03696	ko01100,map01100				ko00000,ko03110				Bacteria	1TPMU@1239,4HACY@91061,COG0542@1,COG0542@2	NA|NA|NA	O	Belongs to the ClpA ClpB family
AHPHCOMF_01136	904306.HMPREF9192_0524	3.5e-150	537.7	Bacilli	dacA	GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100				ko00000,ko00001,ko01000,ko01002,ko01011				Bacteria	1TQN0@1239,4HBD4@91061,COG1686@1,COG1686@2	NA|NA|NA	M	Belongs to the peptidase S11 family
AHPHCOMF_01137	1046629.Ssal_02093	1.8e-32	144.8	Bacilli	dacA	GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100				ko00000,ko00001,ko01000,ko01002,ko01011				Bacteria	1TQN0@1239,4HBD4@91061,COG1686@1,COG1686@2	NA|NA|NA	M	Belongs to the peptidase S11 family
AHPHCOMF_01138	264199.stu0796	1.2e-165	589.0	Firmicutes													Bacteria	1TQEG@1239,COG2801@1,COG2801@2	NA|NA|NA	L	integrase core domain
AHPHCOMF_01139	322159.STER_0111	4.3e-121	440.7	Bacilli				ko:K07483					ko00000				Bacteria	1V4FD@1239,4IQ19@91061,COG2963@1,COG2963@2	NA|NA|NA	L	Helix-turn-helix domain
AHPHCOMF_01140	264199.stu0080	4.2e-231	807.0	Bacilli	dacA	GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100				ko00000,ko00001,ko01000,ko01002,ko01011				Bacteria	1TQN0@1239,4HBD4@91061,COG1686@1,COG1686@2	NA|NA|NA	M	Belongs to the peptidase S11 family
AHPHCOMF_01141	264199.stu0081	0.0	1357.8	Bacilli	pnp	GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019				Bacteria	1TQDW@1239,4H9Z3@91061,COG1185@1,COG1185@2	NA|NA|NA	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
AHPHCOMF_01142	322159.STER_0115	1.3e-105	389.0	Bacilli													Bacteria	1VY65@1239,2F67I@1,33YRI@2,4HXHY@91061	NA|NA|NA	S	SseB protein N-terminal domain
AHPHCOMF_01143	264199.stu0083	1.1e-112	412.5	Bacilli	cysE		2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000				Bacteria	1TR42@1239,4HAKS@91061,COG1045@1,COG1045@2	NA|NA|NA	E	serine acetyltransferase
AHPHCOMF_01144	264199.stu0084	1.5e-258	898.3	Bacilli	cysS	GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iECUMN_1333.ECUMN_0566,iJN746.PP_2905	Bacteria	1TP9D@1239,4HA6D@91061,COG0215@1,COG0215@2	NA|NA|NA	J	Belongs to the class-I aminoacyl-tRNA synthetase family
AHPHCOMF_01145	264199.stu0085	4.2e-68	263.8	Bacilli	mrnC	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360		ko:K11145					ko00000,ko01000,ko03009				Bacteria	1VA5V@1239,4HIM3@91061,COG1939@1,COG1939@2	NA|NA|NA	J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AHPHCOMF_01148	264199.stu0088	5.7e-135	486.9	Bacilli	trmH	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218,ko:K03437,ko:K12952					ko00000,ko01000,ko03009,ko03016	3.A.3.23			Bacteria	1TP9G@1239,4HBBI@91061,COG0566@1,COG0566@2	NA|NA|NA	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AHPHCOMF_01149	264199.stu0089	3.5e-91	340.9	Bacilli	yacP			ko:K06962					ko00000				Bacteria	1V9XR@1239,4HFW4@91061,COG3688@1,COG3688@2	NA|NA|NA	S	RNA-binding protein containing a PIN domain
AHPHCOMF_01150	264199.stu0090	1.7e-154	552.0	Bacilli	degV												Bacteria	1TQDI@1239,4HAYQ@91061,COG1307@1,COG1307@2	NA|NA|NA	S	DegV family
AHPHCOMF_01152	411460.RUMTOR_00063	4.7e-32	144.4	Clostridia													Bacteria	1VK84@1239,24UEE@186801,COG1396@1,COG1396@2	NA|NA|NA	K	helix-turn-helix
AHPHCOMF_01153	264199.stu0092	2.3e-181	641.3	Bacilli	panE		1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000				Bacteria	1TSZ1@1239,4HB4T@91061,COG1893@1,COG1893@2	NA|NA|NA	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AHPHCOMF_01154	1046629.Ssal_02077	2e-79	301.6	Bacilli	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113		ko:K02871	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V3HX@1239,4HG0I@91061,COG0102@1,COG0102@2	NA|NA|NA	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AHPHCOMF_01155	264199.stu0094	9.5e-65	252.7	Bacilli	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02996	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V3MQ@1239,4HH3B@91061,COG0103@1,COG0103@2	NA|NA|NA	J	Belongs to the universal ribosomal protein uS9 family
AHPHCOMF_01156	1140003.I573_01163	9.3e-184	649.4	Enterococcaceae													Bacteria	1UH9G@1239,4AZPY@81852,4HCAS@91061,COG0582@1,COG0582@2	NA|NA|NA	L	Phage integrase family
AHPHCOMF_01157	1140003.I573_01162	1.7e-22	111.3	Enterococcaceae													Bacteria	1W27Y@1239,28SUC@1,2ZF42@2,4B3Q1@81852,4HZNS@91061	NA|NA|NA		
AHPHCOMF_01158	1140003.I573_01161	1.3e-154	552.4	Firmicutes													Bacteria	1VB8R@1239,2E1MQ@1,32WYT@2	NA|NA|NA		
AHPHCOMF_01160	1140003.I573_01159	1.3e-134	485.7	Bacteria													Bacteria	COG1674@1,COG1674@2	NA|NA|NA	D	ftsk spoiiie
AHPHCOMF_01161	97139.C824_03791	5.3e-18	97.8	Clostridiaceae													Bacteria	1TPHE@1239,249WR@186801,36EMD@31979,COG1674@1,COG1674@2	NA|NA|NA	D	FtsK/SpoIIIE family
AHPHCOMF_01164	1140003.I573_01155	3.7e-226	791.2	Enterococcaceae	sthIM		2.1.1.72	ko:K07316					ko00000,ko01000,ko02048				Bacteria	1TR8A@1239,4B0M3@81852,4HBP1@91061,COG2189@1,COG2189@2	NA|NA|NA	L	DNA methylase
AHPHCOMF_01165	264199.stu0884	0.0	1565.4	Bacilli	res_1		3.1.21.5	ko:K01156					ko00000,ko01000,ko02048				Bacteria	1TRVK@1239,4HAVG@91061,COG3421@1,COG3421@2	NA|NA|NA	S	Type III restriction
AHPHCOMF_01167	264199.stu0102	8.5e-112	409.8	Bacilli	int												Bacteria	1TRCD@1239,4HDUS@91061,COG0582@1,COG0582@2	NA|NA|NA	L	Belongs to the 'phage' integrase family
AHPHCOMF_01168	264199.stu0102	3.4e-83	314.3	Bacilli	int												Bacteria	1TRCD@1239,4HDUS@91061,COG0582@1,COG0582@2	NA|NA|NA	L	Belongs to the 'phage' integrase family
AHPHCOMF_01169	1095726.HMPREF1116_1530	2.2e-35	154.5	Bacilli													Bacteria	1VJ5D@1239,2DQ86@1,33582@2,4HP0T@91061	NA|NA|NA	S	Helix-turn-helix domain
AHPHCOMF_01171	264199.stu0103	2.4e-117	428.3	Firmicutes													Bacteria	1VCHG@1239,2E16T@1,32WMJ@2	NA|NA|NA		
AHPHCOMF_01173	1114965.Spaf_1839	6.9e-53	213.4	Bacteria	isp2			ko:K21471					ko00000,ko01000,ko01002,ko01011				Bacteria	COG3942@1,COG3942@2	NA|NA|NA	S	pathogenesis
AHPHCOMF_01174	945021.TEH_22050	2.9e-125	454.5	Enterococcaceae	tnp			ko:K07498					ko00000				Bacteria	1TTKR@1239,4B14R@81852,4HCB4@91061,COG3316@1,COG3316@2	NA|NA|NA	L	Transposase IS66 family
AHPHCOMF_01175	904306.HMPREF9192_0491	3.7e-224	783.9	Bacilli	capA			ko:K07282					ko00000				Bacteria	1UZW4@1239,4HBC3@91061,COG2843@1,COG2843@2	NA|NA|NA	M	Bacterial capsule synthesis protein
AHPHCOMF_01176	264199.stu0112	3.6e-39	167.2	Bacilli	gcvR			ko:K07166					ko00000				Bacteria	1VENW@1239,4HNJ4@91061,COG3830@1,COG3830@2	NA|NA|NA	T	UPF0237 protein
AHPHCOMF_01177	264199.stu0113	1.9e-242	844.7	Bacilli	XK27_08635			ko:K09157					ko00000				Bacteria	1TQG8@1239,4HBTU@91061,COG2848@1,COG2848@2	NA|NA|NA	S	UPF0210 protein
AHPHCOMF_01178	264199.stu0114	2.2e-38	164.9	Bacteria	ais												Bacteria	COG0406@1,COG0406@2	NA|NA|NA	G	alpha-ribazole phosphatase activity
AHPHCOMF_01179	264199.stu0116	1.6e-143	515.4	Bacilli	vanY		3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651			ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504				Bacteria	1V1F7@1239,4HBR1@91061,COG1876@1,COG1876@2	NA|NA|NA	M	D-alanyl-D-alanine carboxypeptidase
AHPHCOMF_01180	322159.STER_0160	1.3e-102	379.0	Bacteria	acmA		3.2.1.17	ko:K01185,ko:K02395					ko00000,ko01000,ko02035				Bacteria	COG1705@1,COG1705@2	NA|NA|NA	NU	amidase activity
AHPHCOMF_01181	264199.stu0118	5.3e-198	696.8	Bacilli	hrcA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141		ko:K03705					ko00000,ko03000				Bacteria	1TQP7@1239,4HAX5@91061,COG1420@1,COG1420@2	NA|NA|NA	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
AHPHCOMF_01182	322159.STER_0162	1.3e-71	276.2	Bacilli	grpE	GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009628,GO:0009986,GO:0009987,GO:0009991,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030246,GO:0030247,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071496,GO:0071840,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065		ko:K03687					ko00000,ko03029,ko03110				Bacteria	1V6G2@1239,4HIRK@91061,COG0576@1,COG0576@2	NA|NA|NA	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AHPHCOMF_01183	322159.STER_0163	9.8e-298	1028.9	Bacilli	dnaK	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065		ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152				ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1			Bacteria	1TP1J@1239,4HA9S@91061,COG0443@1,COG0443@2	NA|NA|NA	O	Heat shock 70 kDa protein
AHPHCOMF_01184	264199.stu0121	4.2e-190	670.6	Bacilli	dnaJ			ko:K03686					ko00000,ko03029,ko03110				Bacteria	1TP00@1239,4H9KA@91061,COG0484@1,COG0484@2	NA|NA|NA	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
AHPHCOMF_01185	264199.stu0122	2.5e-138	498.0	Bacilli	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173					ko00000,ko01000,ko03016				Bacteria	1TQUY@1239,4HCFI@91061,COG0101@1,COG0101@2	NA|NA|NA	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
AHPHCOMF_01186	264199.stu0123	6.2e-137	493.4	Bacilli	thiD		2.7.1.35,2.7.1.49,2.7.4.7	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	M00127	R00174,R01909,R02493,R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQ4A@1239,4H9PP@91061,COG0351@1,COG0351@2	NA|NA|NA	H	phosphomethylpyrimidine kinase
AHPHCOMF_01187	264199.stu0124	1.7e-60	238.4	Bacilli	hmpT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944											Bacteria	1V1E7@1239,4HGDE@91061,COG4720@1,COG4720@2	NA|NA|NA	S	membrane
AHPHCOMF_01200	264199.stu0126	2.5e-169	601.3	Firmicutes													Bacteria	1TQ93@1239,COG3464@1,COG3464@2	NA|NA|NA	L	Transposase
AHPHCOMF_01201	1095738.HMPREF1047_0924	9.9e-19	99.0	Streptococcus oralis													Bacteria	1TWZ1@1239,1WPY9@1303,2DJ35@1,304P3@2,4I5TZ@91061	NA|NA|NA	S	Domain of unknown function (DUF4649)
AHPHCOMF_01202	264199.stu0127	1.8e-56	224.9	Bacilli	amd		3.5.1.47	ko:K01436,ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00525	R02733	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000,ko01002				Bacteria	1TPD7@1239,4H9WQ@91061,COG1473@1,COG1473@2	NA|NA|NA	E	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
AHPHCOMF_01203	322159.STER_0187	1.5e-233	815.1	Bacilli	cfa		2.1.1.317,2.1.1.79	ko:K00574,ko:K20238					ko00000,ko01000				Bacteria	1TSG4@1239,4HDKI@91061,COG2230@1,COG2230@2	NA|NA|NA	M	cyclopropane-fatty-acyl-phospholipid synthase
AHPHCOMF_01204	264199.stu0129	6.5e-87	326.6	Bacteria													Bacteria	COG3464@1,COG3464@2	NA|NA|NA		
AHPHCOMF_01205	1046629.Ssal_02044	1.6e-77	295.4	Bacteria	sigH			ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024				ko00000,ko00001,ko03000,ko03021				Bacteria	COG1595@1,COG1595@2	NA|NA|NA	K	DNA-templated transcription, initiation
AHPHCOMF_01206	264199.stu0131	6.6e-148	530.0	Bacilli	ykuT	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0042802,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004		ko:K22044					ko00000,ko02000	1.A.23.3			Bacteria	1TR9Z@1239,4HCB8@91061,COG0668@1,COG0668@2	NA|NA|NA	M	mechanosensitive ion channel
AHPHCOMF_01207	322159.STER_0191	6.4e-219	766.5	Bacilli	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464		ko:K03545					ko00000				Bacteria	1TQQ8@1239,4H9Q8@91061,COG0544@1,COG0544@2	NA|NA|NA	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
AHPHCOMF_01208	322159.STER_0192	4.8e-73	280.8	Bacilli	rpoE	GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576		ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko03021,ko03400				Bacteria	1V6WX@1239,4HIUK@91061,COG3343@1,COG3343@2	NA|NA|NA	K	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
AHPHCOMF_01209	264199.stu0134	7.6e-310	1068.9	Bacilli	pyrG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000			iHN637.CLJU_RS01075,iNJ661.Rv1699	Bacteria	1TP34@1239,4H9X6@91061,COG0504@1,COG0504@2	NA|NA|NA	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
AHPHCOMF_01210	322159.STER_0194	1.3e-84	318.9	Bacilli	XK27_03960												Bacteria	1VFZQ@1239,2E0MY@1,32W75@2,4HKWR@91061	NA|NA|NA	S	Protein of unknown function (DUF3013)
AHPHCOMF_01211	322159.STER_0195	3.7e-81	307.4	Bacilli	mutT3		3.6.1.13,3.6.1.55	ko:K01515,ko:K03574	ko00230,map00230		R01054	RC00002	ko00000,ko00001,ko01000,ko03400				Bacteria	1V8D5@1239,4HJKW@91061,COG0494@1,COG0494@2	NA|NA|NA	L	NUDIX domain
AHPHCOMF_01212	322159.STER_0196	3.7e-179	634.0	Bacilli	prmA			ko:K02687					ko00000,ko01000,ko03009				Bacteria	1TPKI@1239,4HAMF@91061,COG2264@1,COG2264@2	NA|NA|NA	J	Ribosomal protein L11 methyltransferase
AHPHCOMF_01213	322159.STER_0197	4.4e-135	487.3	Bacilli	rsmE	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761					ko00000,ko01000,ko03009				Bacteria	1V1CT@1239,4HH8P@91061,COG1385@1,COG1385@2	NA|NA|NA	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
AHPHCOMF_01214	322159.STER_0198	0.0	1529.6	Bacilli	cpdB	GO:0003674,GO:0003824,GO:0004112,GO:0005575,GO:0005623,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008252,GO:0008254,GO:0008663,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0030288,GO:0030313,GO:0031975,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0042597,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240		R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000			iEC55989_1330.EC55989_4773,iECH74115_1262.ECH74115_5730,iECNA114_1301.ECNA114_4436,iECSP_1301.ECSP_5315,iECW_1372.ECW_m4577,iECs_1301.ECs5191,iEKO11_1354.EKO11_4095,iEcE24377_1341.EcE24377A_4783,iG2583_1286.G2583_5043,iWFL_1372.ECW_m4577,iZ_1308.Z5824	Bacteria	1TPV2@1239,4HB9S@91061,COG0737@1,COG0737@2	NA|NA|NA	F	Belongs to the 5'-nucleotidase family
AHPHCOMF_01215	322159.STER_0199	2.4e-83	314.7	Bacilli	nrdI			ko:K03647					ko00000				Bacteria	1V71V@1239,4HIW7@91061,COG1780@1,COG1780@2	NA|NA|NA	F	Belongs to the NrdI family
AHPHCOMF_01216	322159.STER_0200	0.0	1437.9	Bacilli	relA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657	2.7.6.5	ko:K00951	ko00230,map00230		R00429	RC00002,RC00078	ko00000,ko00001,ko01000			iHN637.CLJU_RS16615,iYO844.BSU27600	Bacteria	1TNYZ@1239,4HBX7@91061,COG0317@1,COG0317@2	NA|NA|NA	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AHPHCOMF_01217	264199.stu0146	2.3e-75	288.1	Bacilli	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360		ko:K07560					ko00000,ko01000,ko03016				Bacteria	1V6GH@1239,4HINN@91061,COG1490@1,COG1490@2	NA|NA|NA	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
AHPHCOMF_01218	1046629.Ssal_02025	1.4e-09	68.2	Bacilli	dex		3.2.1.11	ko:K05988	ko00500,map00500		R11309		ko00000,ko00001,ko01000		GH66		Bacteria	1TS2G@1239,4HF5J@91061,COG5297@1,COG5297@2	NA|NA|NA	G	Glycosyl hydrolase family 66
AHPHCOMF_01219	1046629.Ssal_02025	2e-27	128.3	Bacilli	dex		3.2.1.11	ko:K05988	ko00500,map00500		R11309		ko00000,ko00001,ko01000		GH66		Bacteria	1TS2G@1239,4HF5J@91061,COG5297@1,COG5297@2	NA|NA|NA	G	Glycosyl hydrolase family 66
AHPHCOMF_01220	1046629.Ssal_02025	2.1e-58	231.9	Bacilli	dex		3.2.1.11	ko:K05988	ko00500,map00500		R11309		ko00000,ko00001,ko01000		GH66		Bacteria	1TS2G@1239,4HF5J@91061,COG5297@1,COG5297@2	NA|NA|NA	G	Glycosyl hydrolase family 66
AHPHCOMF_01221	435842.HMPREF0848_01478	1.9e-45	189.5	Bacilli	dex		3.2.1.11	ko:K05988	ko00500,map00500		R11309		ko00000,ko00001,ko01000		GH66		Bacteria	1TS2G@1239,4HF5J@91061,COG5297@1,COG5297@2	NA|NA|NA	G	Glycosyl hydrolase family 66
AHPHCOMF_01222	322159.STER_0204	1.7e-237	828.2	Bacilli	ilvA	GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP22@1239,4H9NK@91061,COG1171@1,COG1171@2	NA|NA|NA	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AHPHCOMF_01223	264199.stu0151	3.3e-112	411.0	Bacilli	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.31,3.5.1.88	ko:K01450,ko:K01462	ko00270,ko00630,map00270,map00630		R00653	RC00165,RC00323	ko00000,ko00001,ko01000				Bacteria	1V5C6@1239,4HGUI@91061,COG0242@1,COG0242@2	NA|NA|NA	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
AHPHCOMF_01224	322159.STER_0206	5.3e-113	413.7	Bacilli	fnr5												Bacteria	1V2AH@1239,4HFNC@91061,COG0664@1,COG0664@2	NA|NA|NA	K	Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
AHPHCOMF_01225	322159.STER_0207	6.5e-202	709.9	Bacilli	yhjX			ko:K03449,ko:K08177					ko00000,ko02000	2.A.1.11,2.A.1.17			Bacteria	1TSM5@1239,4HF98@91061,COG2807@1,COG2807@2	NA|NA|NA	P	Major Facilitator
AHPHCOMF_01226	264199.stu0154	9.2e-43	179.1	Bacilli	rpsO	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02956	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1VA5C@1239,4HKE9@91061,COG0184@1,COG0184@2	NA|NA|NA	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AHPHCOMF_01227	264199.stu0155	5e-94	350.5	Bacteria													Bacteria	COG4767@1,COG4767@2	NA|NA|NA	V	VanZ like family
AHPHCOMF_01229	264199.stu0158	1e-123	449.5	Bacilli	glnQ			ko:K17074,ko:K17076	ko02010,map02010	M00589			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.20			Bacteria	1TNYD@1239,4H9WY@91061,COG1126@1,COG1126@2	NA|NA|NA	E	abc transporter atp-binding protein
AHPHCOMF_01230	322159.STER_0214	1.8e-276	958.0	Bacilli	glnP			ko:K02029,ko:K02030,ko:K10040,ko:K17073,ko:K17074	ko02010,map02010	M00228,M00236,M00589			ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.20			Bacteria	1TPM3@1239,4HAS2@91061,COG0765@1,COG0765@2,COG0834@1,COG0834@2	NA|NA|NA	P	ABC transporter
AHPHCOMF_01231	322159.STER_0215	9.1e-153	546.2	Bacilli	uppP	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031224,GO:0031226,GO:0042221,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050380,GO:0050896,GO:0071944	3.6.1.27	ko:K06153	ko00550,map00550		R05627	RC00002	ko00000,ko00001,ko01000,ko01011			iYL1228.KPN_03461	Bacteria	1TPFA@1239,4HB0M@91061,COG1968@1,COG1968@2	NA|NA|NA	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
AHPHCOMF_01232	322159.STER_0216	2.3e-136	491.5	Bacilli	mecA	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141		ko:K16511					ko00000				Bacteria	1UZ7D@1239,4HID6@91061,COG4862@1,COG4862@2	NA|NA|NA	NOT	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
AHPHCOMF_01233	322159.STER_0217	1.1e-185	656.0	Bacilli	tagO	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576	2.7.8.33,2.7.8.35	ko:K02851			R08856	RC00002	ko00000,ko01000,ko01003,ko01005				Bacteria	1TP9V@1239,4H9KT@91061,COG0472@1,COG0472@2	NA|NA|NA	M	transferase
AHPHCOMF_01234	264199.stu0164	9.5e-144	516.2	Bacilli	sufC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840		ko:K09013					ko00000,ko02000			iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710	Bacteria	1TQ98@1239,4HAD9@91061,COG0396@1,COG0396@2	NA|NA|NA	O	ABC-type transport system involved in Fe-S cluster assembly, ATPase component
AHPHCOMF_01235	322159.STER_0219	6.3e-235	819.7	Bacilli	sufD			ko:K07033,ko:K09015					ko00000				Bacteria	1TRT0@1239,4HB6W@91061,COG0719@1,COG0719@2	NA|NA|NA	O	assembly protein SufD
AHPHCOMF_01236	264199.stu0166	1e-237	828.9	Bacilli	sufS		2.8.1.7,4.4.1.16	ko:K04487,ko:K11717	ko00450,ko00730,ko01100,ko04122,map00450,map00730,map01100,map04122		R03599,R07460,R11528,R11529	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029				Bacteria	1TQ1W@1239,4HA6Z@91061,COG0520@1,COG0520@2	NA|NA|NA	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AHPHCOMF_01237	322159.STER_0221	1.1e-74	285.8	Bacilli	nifU	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564		ko:K04488					ko00000				Bacteria	1V3H9@1239,4HIJ0@91061,COG0822@1,COG0822@2	NA|NA|NA	C	SUF system FeS assembly protein, NifU family
AHPHCOMF_01238	322159.STER_0222	3.5e-274	950.3	Bacilli	sufB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360		ko:K07033,ko:K09014					ko00000				Bacteria	1TQ21@1239,4HA1Z@91061,COG0719@1,COG0719@2	NA|NA|NA	O	assembly protein SufB
AHPHCOMF_01239	1046629.Ssal_02004	7e-10	68.9	Bacilli	oppA			ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1TNYQ@1239,4HAMK@91061,COG4166@1,COG4166@2	NA|NA|NA	E	ABC transporter substrate-binding protein
AHPHCOMF_01240	264199.stu0170	2e-138	498.4	Bacilli	oppA			ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1TNYQ@1239,4HAMK@91061,COG4166@1,COG4166@2	NA|NA|NA	E	ABC transporter substrate-binding protein
AHPHCOMF_01241	1046629.Ssal_02003	4.2e-27	126.7	Bacilli	oppB			ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1TP1S@1239,4HA2S@91061,COG0601@1,COG0601@2	NA|NA|NA	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AHPHCOMF_01242	1046629.Ssal_02002	6.6e-11	72.4	Bacilli	oppC			ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1TP4R@1239,4H9PZ@91061,COG1173@1,COG1173@2	NA|NA|NA	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AHPHCOMF_01243	264199.stu0172	7.3e-74	283.5	Bacilli	oppC			ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1TP4R@1239,4H9PZ@91061,COG1173@1,COG1173@2	NA|NA|NA	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AHPHCOMF_01244	264199.stu0173	1.4e-38	165.2	Bacilli	oppC			ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1TP4R@1239,4H9PZ@91061,COG1173@1,COG1173@2	NA|NA|NA	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AHPHCOMF_01245	264199.stu0174	3e-27	127.1	Bacteria	oppD			ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	COG0444@1,COG0444@2	NA|NA|NA	P	Belongs to the ABC transporter superfamily
AHPHCOMF_01246	264199.stu0175	2.5e-32	144.1	Bacteria	oppD			ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	COG0444@1,COG0444@2	NA|NA|NA	P	Belongs to the ABC transporter superfamily
AHPHCOMF_01247	264199.stu0176	1.7e-61	241.9	Bacilli	oppD			ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1TP6E@1239,4HA4E@91061,COG0444@1,COG0444@2	NA|NA|NA	P	Belongs to the ABC transporter superfamily
AHPHCOMF_01248	1046629.Ssal_02001	3.1e-43	180.6	Bacilli	oppD			ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1TP6E@1239,4HA4E@91061,COG0444@1,COG0444@2	NA|NA|NA	P	Belongs to the ABC transporter superfamily
AHPHCOMF_01249	322159.STER_0227	9e-170	602.8	Bacilli	oppF			ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1V36J@1239,4H9YB@91061,COG4608@1,COG4608@2	NA|NA|NA	P	Belongs to the ABC transporter superfamily
AHPHCOMF_01252	322159.STER_0230	1.9e-158	565.1	Bacilli	hslO	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0031647,GO:0036506,GO:0042026,GO:0042802,GO:0043167,GO:0043169,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0065007,GO:0065008		ko:K04083					ko00000,ko03110				Bacteria	1TRCH@1239,4HAFR@91061,COG1281@1,COG1281@2	NA|NA|NA	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AHPHCOMF_01253	322159.STER_0231	7.4e-183	646.4	Bacilli	dus			ko:K05540					ko00000,ko01000,ko03016				Bacteria	1TQ2R@1239,4HA9K@91061,COG0042@1,COG0042@2	NA|NA|NA	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AHPHCOMF_01254	264199.stu0184	1.9e-223	781.6	Bacilli													Bacteria	1UG5D@1239,2ZBIK@2,4H9W5@91061,COG0477@1	NA|NA|NA	EGP	Major facilitator Superfamily
AHPHCOMF_01255	264199.stu0185	3.1e-72	277.7	Bacilli	adcR												Bacteria	1VXZT@1239,4HXMU@91061,COG1846@1,COG1846@2	NA|NA|NA	K	transcriptional
AHPHCOMF_01256	264199.stu0186	6.4e-136	490.0	Bacilli	adcC			ko:K09817	ko02010,map02010	M00242			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5		iHN637.CLJU_RS15665,iYO844.BSU02860	Bacteria	1TQ68@1239,4HAZI@91061,COG1121@1,COG1121@2	NA|NA|NA	P	ABC transporter, ATP-binding protein
AHPHCOMF_01257	264199.stu0187	2.5e-128	464.9	Bacilli	adcB	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944		ko:K09816	ko02010,map02010	M00242			ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5			Bacteria	1TR79@1239,4HC3C@91061,COG1108@1,COG1108@2	NA|NA|NA	P	ABC transporter (Permease
AHPHCOMF_01258	322159.STER_0236	1.4e-162	578.9	Bacilli	mleP2			ko:K07088					ko00000				Bacteria	1UY4N@1239,4HB48@91061,COG0679@1,COG0679@2	NA|NA|NA	S	Transporter, auxin efflux carrier (AEC) family protein
AHPHCOMF_01259	264199.stu0189	5.6e-65	253.4	Bacilli	ptsG		2.7.1.199,2.7.1.208	ko:K02777,ko:K02778,ko:K02779,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	M00265,M00266,M00268,M00270,M00272,M00303,M00806	R02738,R02780,R04111,R04394,R05132,R08559	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1,4.A.1.1.11,4.A.1.1.12			Bacteria	1TPJ8@1239,4HA8X@91061,COG1263@1,COG1263@2	NA|NA|NA	G	pts system
AHPHCOMF_01260	264199.stu0191	2.1e-150	538.5	Bacilli	ptsG		2.7.1.199,2.7.1.208,2.7.1.211	ko:K02756,ko:K02777,ko:K02778,ko:K02779,ko:K02808,ko:K02809,ko:K02810,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	M00265,M00266,M00268,M00269,M00270,M00271,M00272,M00303,M00806	R00811,R02738,R02780,R04111,R04394,R05132,R08559	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1,4.A.1.1.11,4.A.1.1.12,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9			Bacteria	1TPJ8@1239,4HA8X@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2	NA|NA|NA	G	pts system
AHPHCOMF_01261	264199.stu0192	1.6e-106	392.1	Bacilli	ptsG		2.7.1.199,2.7.1.208,2.7.1.211	ko:K02756,ko:K02777,ko:K02778,ko:K02779,ko:K02808,ko:K02809,ko:K02810,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	M00265,M00266,M00268,M00269,M00270,M00271,M00272,M00303,M00806	R00811,R02738,R02780,R04111,R04394,R05132,R08559	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1,4.A.1.1.11,4.A.1.1.12,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9			Bacteria	1UJ3K@1239,4IT0V@91061,COG1264@1,COG1264@2,COG2190@1,COG2190@2	NA|NA|NA	G	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
AHPHCOMF_01262	264199.stu0193	6.8e-158	563.1	Bacilli	rgfB		3.1.3.90	ko:K06896	ko00500,map00500		R10486	RC00017	ko00000,ko00001,ko01000				Bacteria	1TQZG@1239,4HGS5@91061,COG3568@1,COG3568@2	NA|NA|NA	L	Endonuclease/Exonuclease/phosphatase family
AHPHCOMF_01263	264199.stu0194	2.8e-257	894.0	Bacilli	pgi	GO:0003674,GO:0003824,GO:0004347,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147			iLJ478.TM1385	Bacteria	1TP29@1239,4H9VI@91061,COG0166@1,COG0166@2	NA|NA|NA	G	Belongs to the GPI family
AHPHCOMF_01264	264199.stu0195	1.9e-127	461.8	Bacilli	yeeN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464											Bacteria	1TPP5@1239,4H9WJ@91061,COG0217@1,COG0217@2	NA|NA|NA	K	transcriptional regulatory protein
AHPHCOMF_01265	264199.stu0196	9.8e-50	202.6	Bacteria	yajC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944		ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2			Bacteria	COG1862@1,COG1862@2	NA|NA|NA	U	protein transport
AHPHCOMF_01266	264199.stu0197	1.1e-141	509.2	Bacilli	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110		R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006				Bacteria	1TQTS@1239,4HA37@91061,COG0020@1,COG0020@2	NA|NA|NA	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AHPHCOMF_01267	264199.stu0198	2.2e-145	521.5	Bacilli	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000			iSB619.SA_RS06255	Bacteria	1TT0Q@1239,4HAMN@91061,COG4589@1,COG4589@2	NA|NA|NA	S	Belongs to the CDS family
AHPHCOMF_01268	322159.STER_0246	1.4e-231	808.5	Bacilli	rseP	GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0040007,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	3.4.21.107,3.4.21.116	ko:K04771,ko:K06399,ko:K11749,ko:K16922	ko01503,ko02020,ko02024,ko04112,map01503,map02020,map02024,map04112	M00728			ko00000,ko00001,ko00002,ko01000,ko01002,ko03110				Bacteria	1TPMC@1239,4HAQ5@91061,COG0750@1,COG0750@2	NA|NA|NA	M	zinc metalloprotease
AHPHCOMF_01269	322159.STER_0247	0.0	1209.5	Bacilli	proS	GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iJN678.proS,iUTI89_1310.UTI89_C0210	Bacteria	1TRBV@1239,4H9NN@91061,COG0442@1,COG0442@2	NA|NA|NA	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
AHPHCOMF_01270	264199.stu0201	0.0	1132.5	Firmicutes	WQ51_06230			ko:K01989,ko:K05832		M00247			ko00000,ko00002,ko02000				Bacteria	1TPB0@1239,COG2984@1,COG2984@2,COG4120@1,COG4120@2	NA|NA|NA	S	ABC transporter substrate binding protein
AHPHCOMF_01271	264199.stu0202	5.2e-142	510.4	Bacilli	cmpC			ko:K05833		M00247			ko00000,ko00002,ko02000				Bacteria	1TPAN@1239,4HCHC@91061,COG1101@1,COG1101@2	NA|NA|NA	S	abc transporter atp-binding protein
AHPHCOMF_01272	264199.stu0203	1.3e-42	178.7	Bacteria	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0032991,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:0101031,GO:1903506,GO:1990220,GO:2000112,GO:2001141		ko:K04078					ko00000,ko03029,ko03110				Bacteria	COG0234@1,COG0234@2	NA|NA|NA	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AHPHCOMF_01273	264199.stu0204	4.1e-287	993.4	Bacilli	groL	GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065		ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152				ko00000,ko00001,ko03019,ko03029,ko03110,ko04147				Bacteria	1TP1T@1239,4HA38@91061,COG0459@1,COG0459@2	NA|NA|NA	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
AHPHCOMF_01274	322159.STER_0016	4.4e-37	160.2	Firmicutes				ko:K07483					ko00000				Bacteria	1W68S@1239,COG2963@1,COG2963@2	NA|NA|NA	L	Transposase
AHPHCOMF_01275	322159.STER_0055	1.9e-17	94.4	Bacteria				ko:K07483					ko00000				Bacteria	COG2963@1,COG2963@2	NA|NA|NA	L	transposase activity
AHPHCOMF_01278	435842.HMPREF0848_01529	4.7e-43	180.3	Bacteria													Bacteria	2C0H5@1,2ZRTJ@2	NA|NA|NA		
AHPHCOMF_01279	322159.STER_0258	9.9e-55	219.2	Bacilli													Bacteria	1VKEZ@1239,4HS74@91061,COG2314@1,COG2314@2	NA|NA|NA	S	TM2 domain
AHPHCOMF_01280	264199.stu0211	1.2e-165	589.0	Bacilli	rluA	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180					ko00000,ko01000,ko03009				Bacteria	1TSM6@1239,4HA7M@91061,COG0564@1,COG0564@2	NA|NA|NA	J	Responsible for synthesis of pseudouridine from uracil
AHPHCOMF_01281	322159.STER_0260	0.0	1502.3	Bacilli	pbp2A		2.4.1.129,3.4.16.4	ko:K03693,ko:K05365,ko:K05366,ko:K12555,ko:K21464	ko00550,ko01100,ko01501,map00550,map01100,map01501		R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011		GT51		Bacteria	1TPM5@1239,4H9SA@91061,COG0744@1,COG0744@2	NA|NA|NA	M	penicillin-binding protein
AHPHCOMF_01282	264199.stu0213	3.3e-21	106.7	Bacteria	rpmG			ko:K02913	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	COG0267@1,COG0267@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL33 family
AHPHCOMF_01283	322159.STER_0262	5.7e-25	119.4	Firmicutes	secE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944		ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2			Bacteria	1W4QH@1239,COG0690@1,COG0690@2	NA|NA|NA	U	Belongs to the SecE SEC61-gamma family
AHPHCOMF_01284	1046629.Ssal_01967	8.4e-96	356.3	Bacilli	nusG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141		ko:K02601					ko00000,ko03009,ko03021				Bacteria	1TR3P@1239,4HAJA@91061,COG0250@1,COG0250@2	NA|NA|NA	K	Participates in transcription elongation, termination and antitermination
AHPHCOMF_01285	264199.stu0216	4.6e-85	320.5	Bacteria			3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27	ko:K01096,ko:K19302	ko00550,ko00564,ko01100,map00550,map00564,map01100		R02029,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011				Bacteria	COG0671@1,COG0671@2	NA|NA|NA	I	phosphatidate phosphatase activity
AHPHCOMF_01286	264199.stu0217	6e-55	219.9	Bacteria	cof												Bacteria	COG0561@1,COG0561@2	NA|NA|NA	Q	phosphatase activity
AHPHCOMF_01287	264199.stu0218	1.1e-34	152.1	Bacteria	cof												Bacteria	COG0561@1,COG0561@2	NA|NA|NA	Q	phosphatase activity
AHPHCOMF_01288	264199.stu0219	3.1e-136	491.1	Bacilli	glcR			ko:K02444,ko:K22103					ko00000,ko03000				Bacteria	1V6VV@1239,4HK1E@91061,COG1349@1,COG1349@2	NA|NA|NA	K	transcriptional regulator (DeoR family)
AHPHCOMF_01289	264199.stu0220	0.0	1711.4	Bacilli	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029				Bacteria	1TP0Y@1239,4HAG1@91061,COG0495@1,COG0495@2	NA|NA|NA	J	Belongs to the class-I aminoacyl-tRNA synthetase family
AHPHCOMF_01290	1046629.Ssal_01960	3.8e-40	170.6	Bacilli													Bacteria	1V1U2@1239,4HI88@91061,COG1846@1,COG1846@2	NA|NA|NA	K	transcriptional
AHPHCOMF_01292	264199.stu0224	2.6e-76	291.2	Bacteria				ko:K06889					ko00000				Bacteria	COG1073@1,COG1073@2	NA|NA|NA	S	thiolester hydrolase activity
AHPHCOMF_01293	264199.stu0225	1e-139	502.7	Bacilli				ko:K06889					ko00000				Bacteria	1V38K@1239,4HE7V@91061,COG1073@1,COG1073@2	NA|NA|NA	S	COG1073 Hydrolases of the alpha beta superfamily
AHPHCOMF_01294	322159.STER_0273	5.7e-280	969.5	Bacilli	pncB	GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100		R01724	RC00033	ko00000,ko00001,ko01000			iYO844.BSU31750	Bacteria	1TPDW@1239,4HAI4@91061,COG1488@1,COG1488@2	NA|NA|NA	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AHPHCOMF_01295	264199.stu0227	2.1e-151	541.6	Bacilli	nadE	GO:0003674,GO:0003824,GO:0003952,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0033554,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000			iECSE_1348.ECSE_1910,iECW_1372.ECW_m1909,iEKO11_1354.EKO11_2035,iETEC_1333.ETEC_1772,iEcE24377_1341.EcE24377A_1961,iSFV_1184.SFV_1480,iSF_1195.SF1486,iSFxv_1172.SFxv_1676,iSSON_1240.SSON_1418,iS_1188.S1603,iWFL_1372.ECW_m1909	Bacteria	1TQ38@1239,4HA2R@91061,COG0171@1,COG0171@2	NA|NA|NA	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
AHPHCOMF_01296	322159.STER_0275	1.9e-77	295.0	Bacteria	yhaI												Bacteria	COG3152@1,COG3152@2	NA|NA|NA	L	Membrane
AHPHCOMF_01297	322159.STER_0276	4.6e-260	903.3	Bacilli	pepC	GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.4.22.40	ko:K01372					ko00000,ko01000,ko01002				Bacteria	1TRJN@1239,4HBZ9@91061,COG3579@1,COG3579@2	NA|NA|NA	E	aminopeptidase
AHPHCOMF_01298	322159.STER_0277	0.0	1399.4	Bacilli	ponA	GO:0005575,GO:0005576	2.4.1.129,3.4.16.4	ko:K03693,ko:K05365,ko:K05366,ko:K12555,ko:K21464	ko00550,ko01100,ko01501,map00550,map01100,map01501		R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011		GT51		Bacteria	1TPM5@1239,4H9SA@91061,COG0744@1,COG0744@2	NA|NA|NA	M	penicillin-binding protein
AHPHCOMF_01299	264199.stu0231	2.5e-109	401.4	Bacilli	recU	GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360		ko:K03700					ko00000,ko03400				Bacteria	1V3S4@1239,4HGZ7@91061,COG3331@1,COG3331@2	NA|NA|NA	L	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
AHPHCOMF_01300	322159.STER_0279	3.1e-95	354.4	Bacilli	ypsA												Bacteria	1V5Q7@1239,4HECZ@91061,COG4474@1,COG4474@2	NA|NA|NA	S	Belongs to the UPF0398 family
AHPHCOMF_01301	264199.stu0233	2.5e-50	204.5	Bacilli	gpsB			ko:K04074					ko00000,ko03036				Bacteria	1VEQ4@1239,4HKUX@91061,COG3599@1,COG3599@2	NA|NA|NA	D	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
AHPHCOMF_01302	264199.stu0234	1.5e-222	778.5	Bacilli	rlmL	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016423,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.173,2.1.1.264	ko:K07444,ko:K12297			R07234	RC00003	ko00000,ko01000,ko03009				Bacteria	1TP0X@1239,4HBKY@91061,COG0116@1,COG0116@2	NA|NA|NA	L	Belongs to the methyltransferase superfamily
AHPHCOMF_01303	264199.stu0235	1.1e-296	1025.4	Bacilli	mapZ			ko:K20073					ko00000				Bacteria	1VDPS@1239,2DB6P@1,32TWV@2,4HK8Y@91061	NA|NA|NA	D	Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
AHPHCOMF_01304	322159.STER_0284	0.0	2030.4	Bacilli	snf		2.7.11.1	ko:K08282					ko00000,ko01000				Bacteria	1TPFZ@1239,4HAIF@91061,COG0553@1,COG0553@2	NA|NA|NA	L	Superfamily II DNA RNA helicases, SNF2 family'
AHPHCOMF_01305	40041.SZO_03140	2.5e-23	115.9	Streptococcus dysgalactiae group													Bacteria	1M9KI@119603,1TXB8@1239,2DJ6Z@1,304WH@2,4I68V@91061	NA|NA|NA		
AHPHCOMF_01306	264199.stu0239	2.6e-255	887.5	Bacilli	mpl	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0042802,GO:0044424,GO:0044464	6.3.2.4,6.3.2.45,6.3.2.8	ko:K01921,ko:K01924,ko:K02558	ko00471,ko00473,ko00550,ko01100,ko01502,map00471,map00473,map00550,map01100,map01502		R01150,R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011			iSDY_1059.SDY_4251	Bacteria	1TQ5H@1239,4HAR4@91061,COG0773@1,COG0773@2	NA|NA|NA	M	Belongs to the MurCDEF family
AHPHCOMF_01307	264199.stu0240	7.3e-80	303.1	Bacteria	XK27_09675			ko:K07105					ko00000				Bacteria	COG0454@1,COG0454@2	NA|NA|NA	K	-acetyltransferase
AHPHCOMF_01308	264199.stu0241	0.0	1180.6	Bacilli	mltG			ko:K07082					ko00000				Bacteria	1TS48@1239,4HAUV@91061,COG1559@1,COG1559@2	NA|NA|NA	ADL	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AHPHCOMF_01309	264199.stu0242	1.6e-77	295.4	Bacilli	greA	GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576		ko:K03624					ko00000,ko03021				Bacteria	1V44S@1239,4HGZU@91061,COG0782@1,COG0782@2	NA|NA|NA	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
AHPHCOMF_01310	264199.stu0244	5.2e-59	233.4	Firmicutes				ko:K07497					ko00000				Bacteria	1TQQY@1239,COG2801@1,COG2801@2	NA|NA|NA	L	Integrase core domain protein
AHPHCOMF_01311	264199.stu0245	2.9e-165	587.8	Bacilli	yidC			ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9			Bacteria	1TSDN@1239,4HCC8@91061,COG0706@1,COG0706@2	NA|NA|NA	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AHPHCOMF_01312	322159.STER_0293	7e-46	189.5	Bacilli	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120		R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000			iSB619.SA_RS07020,iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036	Bacteria	1VEM9@1239,4HNN7@91061,COG1254@1,COG1254@2	NA|NA|NA	C	Belongs to the acylphosphatase family
AHPHCOMF_01313	264199.stu0247	2.5e-130	471.5	Bacilli	spoU		2.1.1.185	ko:K03218,ko:K03437					ko00000,ko01000,ko03009,ko03016				Bacteria	1V3JP@1239,4HCF5@91061,COG0566@1,COG0566@2	NA|NA|NA	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AHPHCOMF_01314	322159.STER_0295	4.7e-93	347.1	Bacilli	XK27_09705		6.1.1.14	ko:K01879,ko:K06950	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1V4QX@1239,4HHW0@91061,COG1418@1,COG1418@2	NA|NA|NA	S	HD superfamily hydrolase
AHPHCOMF_01315	264199.stu0249	8.8e-98	363.2	Bacilli	ybhL	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K06890					ko00000				Bacteria	1V779@1239,4HIX1@91061,COG0670@1,COG0670@2	NA|NA|NA	S	Belongs to the BI1 family
AHPHCOMF_01318	264199.stu0252	9.6e-244	849.0	Bacilli	lysA		4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPE9@1239,4H9XW@91061,COG0019@1,COG0019@2	NA|NA|NA	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
AHPHCOMF_01319	322159.STER_0300	3.7e-91	340.9	Bacteria													Bacteria	COG1309@1,COG1309@2	NA|NA|NA	K	transcriptional regulator
AHPHCOMF_01320	264199.stu0254	7.6e-36	156.0	Bacilli	yneF			ko:K09976					ko00000				Bacteria	1VDSU@1239,4HM8G@91061,COG3763@1,COG3763@2	NA|NA|NA	S	UPF0154 protein
AHPHCOMF_01321	322159.STER_0302	3.8e-148	530.8	Bacilli	murI	GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0042802,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100		R00260	RC00302	ko00000,ko00001,ko01000,ko01011			iYO844.BSU28390	Bacteria	1TPPR@1239,4HA46@91061,COG0796@1,COG0796@2	NA|NA|NA	M	Provides the (R)-glutamate required for cell wall biosynthesis
AHPHCOMF_01322	264199.stu0256	1.3e-184	652.1	Bacilli	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66,5.1.1.3	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100		R00260,R00426,R00720,R01855,R02100,R02720,R03531	RC00002,RC00302	ko00000,ko00001,ko01000,ko01011				Bacteria	1V6RN@1239,4HCP6@91061,COG0127@1,COG0127@2	NA|NA|NA	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AHPHCOMF_01323	264199.stu0257	3.5e-99	367.5	Bacilli	XK27_09740			ko:K07095					ko00000				Bacteria	1VA0U@1239,4HM24@91061,COG0622@1,COG0622@2	NA|NA|NA	S	Phosphoesterase
AHPHCOMF_01324	322159.STER_0305	7.8e-85	319.7	Bacilli	ykuL												Bacteria	1VFAB@1239,4HRWJ@91061,COG0517@1,COG0517@2	NA|NA|NA	S	CBS domain
AHPHCOMF_01325	264199.stu0259	1.1e-136	492.7	Bacilli	xerD			ko:K04763					ko00000,ko03036				Bacteria	1VY7C@1239,4IT0W@91061,COG4974@1,COG4974@2	NA|NA|NA	L	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
AHPHCOMF_01326	264199.stu0260	9e-122	443.0	Bacilli	scpA	GO:0003674,GO:0005488,GO:0005515,GO:0042802		ko:K05896					ko00000,ko03036				Bacteria	1V8JV@1239,4IQZ5@91061,COG1354@1,COG1354@2	NA|NA|NA	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AHPHCOMF_01327	264199.stu0261	3e-99	367.9	Bacilli	scpB	GO:0003674,GO:0005488,GO:0005515,GO:0042802		ko:K06024					ko00000,ko03036				Bacteria	1V6HI@1239,4HIQ0@91061,COG1386@1,COG1386@2	NA|NA|NA	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AHPHCOMF_01328	264199.stu0262	6.1e-140	503.4	Bacilli	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.21,5.4.99.22	ko:K06178,ko:K06182,ko:K06183					ko00000,ko01000,ko03009				Bacteria	1TP68@1239,4H9MU@91061,COG1187@1,COG1187@2	NA|NA|NA	J	Belongs to the pseudouridine synthase RsuA family
AHPHCOMF_01329	264199.stu0263	1.2e-39	168.7	Bacilli	yidD			ko:K08998					ko00000				Bacteria	1VEIG@1239,4HPA3@91061,COG0759@1,COG0759@2	NA|NA|NA	S	Could be involved in insertion of integral membrane proteins into the membrane
AHPHCOMF_01330	264199.stu0264	1.2e-258	898.7	Bacilli	trkH	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031224,GO:0031226,GO:0031420,GO:0034220,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662		ko:K03498,ko:K03499					ko00000,ko02000	2.A.38.1,2.A.38.4		iECDH1ME8569_1439.ECDH1ME8569_1308,iPC815.YPO3762,iSFV_1184.SFV_3651	Bacteria	1TPAF@1239,4HCWN@91061,COG0168@1,COG0168@2	NA|NA|NA	P	Cation transport protein
AHPHCOMF_01331	264199.stu0265	1.3e-246	858.6	Bacilli	trkA			ko:K03499					ko00000,ko02000	2.A.38.1,2.A.38.4			Bacteria	1TPNS@1239,4HCRM@91061,COG0569@1,COG0569@2	NA|NA|NA	P	Potassium transporter peripheral membrane component
AHPHCOMF_01332	264199.stu0267	3e-95	354.4	Bacilli	trmL	GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.207	ko:K03216					ko00000,ko01000,ko03016				Bacteria	1V3GW@1239,4HFNY@91061,COG0219@1,COG0219@2	NA|NA|NA	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
AHPHCOMF_01333	264199.stu0268	3.2e-90	337.8	Bacilli	ribU	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656											Bacteria	1V4BW@1239,4HHFT@91061,COG3601@1,COG3601@2	NA|NA|NA	U	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AHPHCOMF_01334	264199.stu0269	7e-113	413.3	Bacilli	bcrC		3.6.1.27	ko:K19302	ko00550,map00550		R05627	RC00002	ko00000,ko00001,ko01000,ko01011				Bacteria	1VF2U@1239,4HNXR@91061,COG0671@1,COG0671@2	NA|NA|NA	I	Membrane-associated phospholipid phosphatase
AHPHCOMF_01335	264199.stu0270	1.6e-160	572.0	Bacteria				ko:K20342,ko:K20480	ko02024,map02024				ko00000,ko00001,ko03000				Bacteria	COG1396@1,COG1396@2	NA|NA|NA	K	sequence-specific DNA binding
AHPHCOMF_01336	264199.stu0271	1.9e-33	147.9	Bacteria		GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702		ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024				ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.21			Bacteria	COG2274@1,COG2274@2	NA|NA|NA	V	protein secretion by the type I secretion system
AHPHCOMF_01337	264199.stu0272	3.4e-62	244.2	Bacilli		GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702		ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024				ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.21			Bacteria	1V77J@1239,4HAX2@91061,COG2274@1,COG2274@2	NA|NA|NA	V	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
AHPHCOMF_01338	264199.stu0272	1.1e-36	159.1	Bacilli		GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702		ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024				ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.21			Bacteria	1V77J@1239,4HAX2@91061,COG2274@1,COG2274@2	NA|NA|NA	V	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
AHPHCOMF_01339	264199.stu0275	3.4e-68	264.2	Bacilli	comA			ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024				ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.21			Bacteria	1V77J@1239,4HAX2@91061,COG2274@1,COG2274@2	NA|NA|NA	V	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
AHPHCOMF_01340	264199.stu0276	3.7e-51	207.2	Bacteria	yhaI												Bacteria	COG3152@1,COG3152@2	NA|NA|NA	L	Membrane
AHPHCOMF_01341	1046629.Ssal_01904	6.7e-36	156.4	Firmicutes													Bacteria	1VCM1@1239,2E26M@1,32XD2@2	NA|NA|NA	S	Domain of unknown function (DUF4173)
AHPHCOMF_01342	1046629.Ssal_01904	9.2e-132	476.5	Firmicutes													Bacteria	1VCM1@1239,2E26M@1,32XD2@2	NA|NA|NA	S	Domain of unknown function (DUF4173)
AHPHCOMF_01343	264199.stu0280	6.8e-95	353.2	Firmicutes	ureI	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K03191,ko:K22112	ko05120,map05120				ko00000,ko00001,ko02000	1.A.29.1.1,1.A.29.1.2,1.A.29.1.3,1.A.29.1.4,1.A.29.1.5,1.A.29.1.6			Bacteria	1VAKB@1239,29DTM@1,300RH@2	NA|NA|NA	S	AmiS/UreI family transporter
AHPHCOMF_01344	264199.stu0281	7.6e-46	189.5	Bacilli	ureA	GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0019627,GO:0034641,GO:0042221,GO:0043419,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071704,GO:0071941,GO:1901564,GO:1901565,GO:1901575	3.5.1.5	ko:K01430,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120		R00131	RC02798,RC02806	ko00000,ko00001,ko01000			iYO844.BSU36660	Bacteria	1V7GU@1239,4HIJS@91061,COG0831@1,COG0831@2	NA|NA|NA	E	Belongs to the urease gamma subunit family
AHPHCOMF_01345	1046629.Ssal_01901	7.8e-54	216.1	Bacilli	ureB	GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0019627,GO:0034641,GO:0042221,GO:0043419,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071704,GO:0071941,GO:1901564,GO:1901565,GO:1901575	3.5.1.5	ko:K01429,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120		R00131	RC02798,RC02806	ko00000,ko00001,ko01000				Bacteria	1VAIA@1239,4HM0I@91061,COG0832@1,COG0832@2	NA|NA|NA	E	Belongs to the urease beta subunit family
AHPHCOMF_01346	322159.STER_0325	0.0	1156.7	Bacilli	ureC		3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120		R00131	RC02798,RC02806	ko00000,ko00001,ko01000				Bacteria	1TPQP@1239,4HBTS@91061,COG0804@1,COG0804@2	NA|NA|NA	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
AHPHCOMF_01347	1046629.Ssal_01898	6.6e-78	296.6	Bacteria	ureE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464		ko:K03187					ko00000				Bacteria	COG2371@1,COG2371@2	NA|NA|NA	O	enzyme active site formation
AHPHCOMF_01348	264199.stu0285	5.3e-130	470.3	Bacilli	ureF			ko:K03188					ko00000				Bacteria	1V2H0@1239,4HKQE@91061,COG0830@1,COG0830@2	NA|NA|NA	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
AHPHCOMF_01349	1046629.Ssal_01896	9.5e-112	409.5	Bacilli	ureG			ko:K03189,ko:K04652					ko00000,ko03110				Bacteria	1TS00@1239,4HC5C@91061,COG0378@1,COG0378@2	NA|NA|NA	KO	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AHPHCOMF_01350	264199.stu0287	4.9e-159	567.0	Bacilli	ureD			ko:K03190					ko00000				Bacteria	1TVM2@1239,4HCED@91061,COG0829@1,COG0829@2	NA|NA|NA	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
AHPHCOMF_01351	322159.STER_0330	2.7e-177	627.9	Bacilli	cbiM	GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351		ko:K02007	ko02010,map02010	M00245,M00246			ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23			Bacteria	1TPEN@1239,4HARY@91061,COG0310@1,COG0310@2	NA|NA|NA	P	PDGLE domain
AHPHCOMF_01352	264199.stu0289	1.1e-136	492.7	Firmicutes				ko:K02008	ko02010,map02010	M00245,M00246			ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23			Bacteria	1V7YC@1239,COG0619@1,COG0619@2	NA|NA|NA	P	cobalt transport protein
AHPHCOMF_01353	264199.stu0290	1.6e-131	475.3	Bacilli	cbiO	GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351		ko:K02006	ko02010,map02010	M00245,M00246			ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23			Bacteria	1V16T@1239,4HI15@91061,COG1122@1,COG1122@2	NA|NA|NA	P	ABC transporter
AHPHCOMF_01354	264199.stu0296	4.5e-152	543.9	Bacteria				ko:K02030		M00236			ko00000,ko00002,ko02000	3.A.1.3			Bacteria	COG0834@1,COG0834@2	NA|NA|NA	ET	amino acid transport
AHPHCOMF_01355	264199.stu0297	3.7e-165	587.4	Bacilli	metQ			ko:K02073	ko02010,map02010	M00238			ko00000,ko00001,ko00002,ko02000	3.A.1.24			Bacteria	1TQAS@1239,4HCTA@91061,COG1464@1,COG1464@2	NA|NA|NA	M	Belongs to the NlpA lipoprotein family
AHPHCOMF_01356	264199.stu0298	4.9e-87	327.0	Bacilli	dapE		3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP2D@1239,4HB9G@91061,COG0624@1,COG0624@2	NA|NA|NA	E	COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
AHPHCOMF_01357	264199.stu0299	1.4e-62	245.4	Bacteria	dapE		3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000				Bacteria	COG0624@1,COG0624@2	NA|NA|NA	E	succinyl-diaminopimelate desuccinylase activity
AHPHCOMF_01358	264199.stu0300	1.4e-62	245.4	Bacteria	dapE		3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000				Bacteria	COG0624@1,COG0624@2	NA|NA|NA	E	succinyl-diaminopimelate desuccinylase activity
AHPHCOMF_01359	264199.stu0301	1.2e-189	669.1	Bacilli	metN			ko:K02071	ko02010,map02010	M00238			ko00000,ko00001,ko00002,ko02000	3.A.1.24			Bacteria	1TPPN@1239,4H9VX@91061,COG1135@1,COG1135@2	NA|NA|NA	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AHPHCOMF_01360	264199.stu0302	5.2e-98	364.0	Bacilli	metI			ko:K02072	ko02010,map02010	M00238			ko00000,ko00001,ko00002,ko02000	3.A.1.24			Bacteria	1V0GE@1239,4HFMB@91061,COG2011@1,COG2011@2	NA|NA|NA	P	ABC transporter (Permease
AHPHCOMF_01361	322159.STER_0344	3.9e-210	737.3	Bacilli	sstT	GO:0003333,GO:0003674,GO:0005215,GO:0005283,GO:0005295,GO:0005310,GO:0005342,GO:0005343,GO:0005416,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006820,GO:0006835,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015077,GO:0015081,GO:0015171,GO:0015175,GO:0015291,GO:0015293,GO:0015294,GO:0015318,GO:0015370,GO:0015672,GO:0015711,GO:0015804,GO:0015849,GO:0016020,GO:0016021,GO:0017153,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032329,GO:0034220,GO:0035725,GO:0044425,GO:0044464,GO:0046873,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1903825,GO:1905039		ko:K07862					ko00000,ko02000	2.A.23.4		iAF1260.b3089,iBWG_1329.BWG_2799,iECDH10B_1368.ECDH10B_3265,iECDH1ME8569_1439.ECDH1ME8569_2984,iECH74115_1262.ECH74115_4404,iECIAI1_1343.ECIAI1_3235,iECO103_1326.ECO103_3834,iECO111_1330.ECO111_3911,iECO26_1355.ECO26_4192,iECP_1309.ECP_3180,iECSE_1348.ECSE_3370,iECSP_1301.ECSP_4063,iECUMN_1333.ECUMN_3573,iECW_1372.ECW_m3356,iECs_1301.ECs3971,iEKO11_1354.EKO11_0630,iETEC_1333.ETEC_3359,iEcDH1_1363.EcDH1_0612,iEcE24377_1341.EcE24377A_3557,iG2583_1286.G2583_3813,iJO1366.b3089,iJR904.b3089,iSFV_1184.SFV_3130,iSSON_1240.SSON_3242,iUMNK88_1353.UMNK88_3845,iWFL_1372.ECW_m3356,iY75_1357.Y75_RS16050,iYL1228.KPN_03517,iZ_1308.Z4442	Bacteria	1TPD2@1239,4HBEC@91061,COG3633@1,COG3633@2	NA|NA|NA	E	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AHPHCOMF_01362	322159.STER_0345	5.5e-158	563.5	Bacilli	salL	GO:0003674,GO:0003824,GO:0016740,GO:0016765	2.5.1.63,2.5.1.94	ko:K09134,ko:K21153,ko:K22205					ko00000,ko01000				Bacteria	1TSR3@1239,4HAW6@91061,COG1912@1,COG1912@2	NA|NA|NA	S	S-adenosyl-l-methionine hydroxide adenosyltransferase
AHPHCOMF_01363	322159.STER_0346	8e-94	349.7	Bacilli				ko:K16924,ko:K16927		M00582			ko00000,ko00002,ko02000	3.A.1.29,3.A.1.32			Bacteria	1V1GT@1239,4HGAE@91061,COG4720@1,COG4720@2	NA|NA|NA	S	UPF0397 protein
AHPHCOMF_01364	322159.STER_0347	0.0	1078.9	Bacilli	ykoD	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085		ko:K02006,ko:K16786,ko:K16787	ko02010,map02010	M00245,M00246,M00582			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35			Bacteria	1TPH8@1239,4HAJM@91061,COG1122@1,COG1122@2	NA|NA|NA	P	abc transporter atp-binding protein
AHPHCOMF_01365	322159.STER_0348	1.2e-149	535.8	Bacilli	cbiQ			ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35		iSB619.SA_RS14165	Bacteria	1TPMV@1239,4HBTW@91061,COG0619@1,COG0619@2	NA|NA|NA	P	cobalt transport
AHPHCOMF_01366	264199.stu0312	0.0	1310.4	Bacilli	tkt		2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPIB@1239,4HADA@91061,COG0021@1,COG0021@2	NA|NA|NA	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AHPHCOMF_01367	1123298.KB904063_gene687	1.4e-11	75.5	Bacilli	ulaG	GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009056,GO:0009109,GO:0009111,GO:0009987,GO:0016052,GO:0016054,GO:0016787,GO:0016788,GO:0019752,GO:0019852,GO:0019854,GO:0030145,GO:0035460,GO:0042365,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046872,GO:0046914,GO:0051186,GO:0051187,GO:0052689,GO:0071704,GO:1901575		ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	M00550	R07677	RC02793	ko00000,ko00001,ko00002,ko01000			iAF1260.b4192,iAPECO1_1312.APECO1_2200,iBWG_1329.BWG_3904,iEC55989_1330.EC55989_4749,iECDH10B_1368.ECDH10B_4387,iECH74115_1262.ECH74115_5708,iECIAI1_1343.ECIAI1_4425,iECIAI39_1322.ECIAI39_4657,iECO111_1330.ECO111_5022,iECO26_1355.ECO26_5358,iECSE_1348.ECSE_4490,iECSP_1301.ECSP_5292,iECUMN_1333.ECUMN_4725,iECW_1372.ECW_m4554,iEKO11_1354.EKO11_4120,iEcE24377_1341.EcE24377A_4752,iEcHS_1320.EcHS_A4436,iEcolC_1368.EcolC_3821,iJO1366.b4192,iUTI89_1310.UTI89_C4792,iWFL_1372.ECW_m4554,iY75_1357.Y75_RS21830,iYL1228.KPN_04585,ic_1306.c5280	Bacteria	1TSFV@1239,4HBNW@91061,COG2220@1,COG2220@2	NA|NA|NA	S	L-ascorbate 6-phosphate lactonase
AHPHCOMF_01368	264199.stu0313	1.9e-121	441.8	Bacilli	ktrA			ko:K03499					ko00000,ko02000	2.A.38.1,2.A.38.4			Bacteria	1TQ9H@1239,4HBPH@91061,COG0569@1,COG0569@2	NA|NA|NA	P	COG0569 K transport systems, NAD-binding component
AHPHCOMF_01369	322159.STER_0351	3.4e-242	844.0	Bacilli				ko:K03498					ko00000,ko02000	2.A.38.1,2.A.38.4			Bacteria	1TQ4S@1239,4H9ME@91061,COG0168@1,COG0168@2	NA|NA|NA	P	COG0168 Trk-type K transport systems, membrane components
AHPHCOMF_01370	264199.stu0315	3.1e-130	471.1	Bacilli	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501					ko00000,ko01000,ko03009,ko03036				Bacteria	1TPBT@1239,4HAAZ@91061,COG0357@1,COG0357@2	NA|NA|NA	J	Ribosomal RNA small subunit methyltransferase G
AHPHCOMF_01371	322159.STER_0353	2.1e-91	341.7	Bacilli	yceD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464		ko:K07040					ko00000				Bacteria	1VB08@1239,4HME9@91061,COG1399@1,COG1399@2	NA|NA|NA	K	metal-binding, possibly nucleic acid-binding protein
AHPHCOMF_01372	264199.stu0317	1.8e-122	445.3	Bacilli													Bacteria	1TS81@1239,4H9NE@91061,COG0745@1,COG0745@2	NA|NA|NA	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AHPHCOMF_01373	264199.stu0318	2.8e-282	977.2	Bacilli													Bacteria	1UHQC@1239,4HWKS@91061,COG0642@1,COG2205@2	NA|NA|NA	T	PhoQ Sensor
AHPHCOMF_01374	322159.STER_0356	4.7e-82	310.5	Bacilli	nrdR	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141		ko:K07738					ko00000,ko03000				Bacteria	1V3JA@1239,4HGXA@91061,COG1327@1,COG1327@2	NA|NA|NA	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AHPHCOMF_01375	322159.STER_0357	6.5e-218	763.1	Bacteria	dnaB			ko:K03346					ko00000,ko03032				Bacteria	COG3611@1,COG3611@2	NA|NA|NA	L	Replication initiation and membrane attachment
AHPHCOMF_01376	322159.STER_0358	5.2e-167	593.6	Bacilli	dnaI	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837		ko:K11144					ko00000,ko03032				Bacteria	1TPZX@1239,4HABS@91061,COG1484@1,COG1484@2	NA|NA|NA	L	Primosomal protein DnaI
AHPHCOMF_01377	322159.STER_0359	4.1e-245	853.6	Bacilli	der	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.1.1.399,1.1.1.95	ko:K00058,ko:K03977	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko03009,ko04147				Bacteria	1TPNM@1239,4HAJ6@91061,COG1160@1,COG1160@2	NA|NA|NA	S	GTPase that plays an essential role in the late steps of ribosome biogenesis
AHPHCOMF_01378	904306.HMPREF9192_0087	1.2e-34	152.5	Bacteria													Bacteria	2CH4S@1,32S58@2	NA|NA|NA		
AHPHCOMF_01379	1161413.HMPREF1510_1836	3e-27	127.1	Firmicutes				ko:K07497					ko00000				Bacteria	1TQQY@1239,COG2801@1,COG2801@2	NA|NA|NA	L	Integrase core domain protein
AHPHCOMF_01380	264199.stu0018	3.4e-50	204.1	Bacteria				ko:K07497					ko00000				Bacteria	COG2801@1,COG2801@2	NA|NA|NA	L	transposition
AHPHCOMF_01381	1095738.HMPREF1047_1210	5.7e-23	112.8	Firmicutes				ko:K07483					ko00000				Bacteria	1W68S@1239,COG2963@1,COG2963@2	NA|NA|NA	L	Transposase
AHPHCOMF_01382	322159.STER_0366	7.8e-28	129.0	Bacteria				ko:K07483					ko00000				Bacteria	COG2963@1,COG2963@2	NA|NA|NA	L	transposase activity
AHPHCOMF_01383	264199.stu0329	1.1e-231	808.9	Bacilli	serS	GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iAF987.Gmet_3528,iSDY_1059.SDY_2368	Bacteria	1TP4W@1239,4H9Y4@91061,COG0172@1,COG0172@2	NA|NA|NA	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AHPHCOMF_01384	322159.STER_0369	6.5e-63	246.5	Bacilli	manO												Bacteria	1VF36@1239,4HPYI@91061,COG4687@1,COG4687@2	NA|NA|NA	S	protein conserved in bacteria
AHPHCOMF_01385	264199.stu0331	6.2e-168	596.7	Bacilli	manN			ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1			Bacteria	1TQA3@1239,4HA3K@91061,COG3716@1,COG3716@2	NA|NA|NA	G	PTS system mannose fructose sorbose family IID component
AHPHCOMF_01386	322159.STER_0371	1.7e-116	425.6	Bacilli	manM			ko:K02795,ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1			Bacteria	1TPKK@1239,4H9QI@91061,COG3715@1,COG3715@2	NA|NA|NA	G	pts system
AHPHCOMF_01387	264199.stu0333	1.1e-181	642.5	Bacilli	manL		2.7.1.191	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1			Bacteria	1TQJ4@1239,4H9Z8@91061,COG2893@1,COG2893@2,COG3444@1,COG3444@2	NA|NA|NA	G	pts system
AHPHCOMF_01388	264199.stu0334	1.5e-140	505.4	Bacilli	XK27_00940		1.2.1.70,3.5.1.9	ko:K02492,ko:K07130	ko00380,ko00630,ko00860,ko01100,ko01110,ko01120,map00380,map00630,map00860,map01100,map01110,map01120	M00038,M00121	R00988,R01959,R04109,R04911	RC00055,RC00149,RC00263,RC00323	ko00000,ko00001,ko00002,ko01000				Bacteria	1TRBQ@1239,4HCAB@91061,COG1878@1,COG1878@2	NA|NA|NA	S	Metal-dependent hydrolase
AHPHCOMF_01389	322159.STER_0374	1e-153	549.3	Bacilli	yitU		3.1.3.104	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R07280	RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	1TREF@1239,4H9Y9@91061,COG0561@1,COG0561@2	NA|NA|NA	S	hydrolases of the HAD superfamily
AHPHCOMF_01390	322159.STER_0375	1.9e-248	864.8	Bacilli	pbuO			ko:K06901					ko00000,ko02000	2.A.1.40			Bacteria	1TQC6@1239,4HANG@91061,COG2252@1,COG2252@2	NA|NA|NA	S	permease
AHPHCOMF_01391	264199.stu0337	1.4e-77	295.4	Bacilli	ydiB	GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.7.1.221,5.1.1.1	ko:K01775,ko:K06925,ko:K07102	ko00473,ko00520,ko01100,ko01502,map00473,map00520,map01100,map01502		R00401,R08968,R11024	RC00002,RC00078,RC00285	ko00000,ko00001,ko01000,ko01011,ko03016				Bacteria	1V6CV@1239,4HIIF@91061,COG0802@1,COG0802@2	NA|NA|NA	M	ATPase or kinase
AHPHCOMF_01392	322159.STER_0377	2.4e-92	344.7	Firmicutes	XK27_05885		2.3.1.82	ko:K18816					br01600,ko00000,ko01000,ko01504				Bacteria	1VA2F@1239,COG1247@1,COG1247@2	NA|NA|NA	M	Acetyltransferase GNAT Family
AHPHCOMF_01393	264199.stu0339	2.5e-220	771.2	Bacilli	brpA												Bacteria	1TR1B@1239,4HA09@91061,COG1316@1,COG1316@2	NA|NA|NA	K	Transcriptional
AHPHCOMF_01394	264199.stu0340	3.9e-81	307.4	Bacilli	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576		ko:K09748					ko00000,ko03009				Bacteria	1V6KT@1239,4HH88@91061,COG0779@1,COG0779@2	NA|NA|NA	S	Required for maturation of 30S ribosomal subunits
AHPHCOMF_01395	322159.STER_0380	3.1e-212	744.2	Bacilli	nusA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141		ko:K02600,ko:K02945	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03009,ko03011,ko03021				Bacteria	1TPB3@1239,4HA7F@91061,COG0195@1,COG0195@2	NA|NA|NA	K	Participates in both transcription termination and antitermination
AHPHCOMF_01396	264199.stu0342	1e-47	195.7	Bacilli	ylxR			ko:K02600,ko:K07742					ko00000,ko03009,ko03021				Bacteria	1VEJS@1239,4HKBY@91061,COG2740@1,COG2740@2	NA|NA|NA	K	Nucleic-acid-binding protein implicated in transcription termination
AHPHCOMF_01397	264199.stu0343	1.4e-41	175.3	Bacilli	ylxQ			ko:K07590,ko:K07742	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1VEYG@1239,4HNY7@91061,COG1358@1,COG1358@2	NA|NA|NA	J	ribosomal protein
AHPHCOMF_01398	322159.STER_0383	0.0	1186.4	Bacilli	infB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464		ko:K02519					ko00000,ko03012,ko03029				Bacteria	1TPAI@1239,4HA8S@91061,COG0532@1,COG0532@2	NA|NA|NA	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AHPHCOMF_01399	264199.stu0345	1.7e-57	228.4	Bacilli	rbfA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360		ko:K02834					ko00000,ko03009				Bacteria	1VA0P@1239,4HII1@91061,COG0858@1,COG0858@2	NA|NA|NA	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AHPHCOMF_01400	904306.HMPREF9192_0063	2e-22	110.9	Bacilli	yvdD		3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240		R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000				Bacteria	1UKED@1239,4HGSU@91061,COG1611@1,COG1611@2	NA|NA|NA	S	Belongs to the LOG family
AHPHCOMF_01401	435842.HMPREF0848_01648	3.4e-37	160.6	Firmicutes	yvdD		3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240		R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000				Bacteria	1UKED@1239,COG1611@1,COG1611@2	NA|NA|NA	L	Belongs to the LOG family
AHPHCOMF_01403	264199.stu0348	2.1e-213	748.0	Bacilli	femA		2.3.2.10,2.3.2.16,2.3.2.17,2.3.2.18	ko:K05363,ko:K11693,ko:K11694,ko:K11695,ko:K12554	ko00550,ko01100,map00550,map01100		R08776,R08777,R08778,R08779,R08780	RC00055,RC00064,RC00096	ko00000,ko00001,ko01000,ko01011				Bacteria	1UZIJ@1239,4HAQ3@91061,COG2348@1,COG2348@2	NA|NA|NA	V	protein involved in methicillin resistance
AHPHCOMF_01404	264199.stu0349	1.4e-275	954.9	Bacilli	murE		6.3.2.13,6.3.2.7	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100		R02786,R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011				Bacteria	1TPQE@1239,4H9T1@91061,COG0769@1,COG0769@2	NA|NA|NA	M	to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AHPHCOMF_01405	322159.STER_0388	4.5e-283	979.9	Bacilli	ytgP	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K03328,ko:K06409					ko00000,ko02000	2.A.66.2,2.A.66.2.14			Bacteria	1TNYX@1239,4H9RY@91061,COG2244@1,COG2244@2	NA|NA|NA	S	Membrane protein involved in the export of O-antigen and teichoic acid
AHPHCOMF_01406	1046629.Ssal_01842	3.3e-96	357.8	Bacilli	pacL		3.6.3.8,3.6.3.9	ko:K01537,ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978				ko00000,ko00001,ko01000,ko04147	3.A.3.1,3.A.3.2			Bacteria	1TPF5@1239,4HTQ4@91061,COG0474@1,COG0474@2	NA|NA|NA	P	cation transport ATPase
AHPHCOMF_01407	264199.stu0352	1e-201	709.1	Bacilli	metB	GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846	2.5.1.48,4.4.1.8	ko:K01739,ko:K01760	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPC7@1239,4HAFQ@91061,COG0626@1,COG0626@2	NA|NA|NA	E	cystathionine
AHPHCOMF_01408	264199.stu0353	1e-223	782.3	Bacilli	malY		4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230		R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007				Bacteria	1TP5G@1239,4H9PE@91061,COG1168@1,COG1168@2	NA|NA|NA	E	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
AHPHCOMF_01410	264199.stu0355	4.4e-112	410.6	Bacilli	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100		R00966	RC00063	ko00000,ko00001,ko01000			iSB619.SA_RS11010	Bacteria	1TPMT@1239,4H9Y0@91061,COG0035@1,COG0035@2	NA|NA|NA	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AHPHCOMF_01411	264199.stu0356	2.9e-105	387.9	Bacilli	clpP	GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212				ko00000,ko00001,ko01000,ko01002				Bacteria	1TQ91@1239,4HA8J@91061,COG0740@1,COG0740@2	NA|NA|NA	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
AHPHCOMF_01412	322159.STER_0396	3.4e-74	284.3	Bacilli	ylbF												Bacteria	1V3R6@1239,4HGYS@91061,COG3679@1,COG3679@2	NA|NA|NA	S	Belongs to the UPF0342 family
AHPHCOMF_01413	264199.stu0358	7.1e-46	189.5	Bacilli	ylbG												Bacteria	1VF52@1239,4HNTH@91061,COG4471@1,COG4471@2	NA|NA|NA	S	UPF0298 protein
AHPHCOMF_01414	322159.STER_0398	1.1e-212	745.7	Bacilli	livJ			ko:K01999	ko02010,ko02024,map02010,map02024	M00237			ko00000,ko00001,ko00002,ko02000	3.A.1.4			Bacteria	1TPQ2@1239,4H9PI@91061,COG0683@1,COG0683@2	NA|NA|NA	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
AHPHCOMF_01415	264199.stu0360	1.9e-145	521.9	Bacilli	livH			ko:K01997	ko02010,ko02024,map02010,map02024	M00237			ko00000,ko00001,ko00002,ko02000	3.A.1.4			Bacteria	1TR24@1239,4HBFZ@91061,COG0559@1,COG0559@2	NA|NA|NA	E	Belongs to the binding-protein-dependent transport system permease family
AHPHCOMF_01416	264199.stu0361	1.4e-138	499.2	Bacilli	livM			ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237			ko00000,ko00001,ko00002,ko02000	3.A.1.4			Bacteria	1TPMZ@1239,4HDIU@91061,COG4177@1,COG4177@2	NA|NA|NA	E	Belongs to the binding-protein-dependent transport system permease family
AHPHCOMF_01417	322159.STER_0401	9.6e-138	496.1	Bacilli	livG			ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237			ko00000,ko00001,ko00002,ko02000	3.A.1.4			Bacteria	1TR0P@1239,4HASG@91061,COG0411@1,COG0411@2	NA|NA|NA	E	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
AHPHCOMF_01418	322159.STER_0402	9.6e-124	449.5	Bacilli	livF			ko:K01996	ko02010,ko02024,map02010,map02024	M00237			ko00000,ko00001,ko00002,ko02000	3.A.1.4			Bacteria	1TPW4@1239,4HABJ@91061,COG0410@1,COG0410@2	NA|NA|NA	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
AHPHCOMF_01419	264199.stu0364	2.8e-70	271.2	Bacteria	acuB			ko:K04767					ko00000				Bacteria	COG0517@1,COG0517@2	NA|NA|NA	S	IMP dehydrogenase activity
AHPHCOMF_01420	264199.stu0365	3.3e-43	180.6	Bacteria	acuB			ko:K04767					ko00000				Bacteria	COG0517@1,COG0517@2	NA|NA|NA	S	IMP dehydrogenase activity
AHPHCOMF_01421	322159.STER_0404	2.2e-168	598.2	Bacilli	cysK	GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP30@1239,4HAMU@91061,COG0031@1,COG0031@2	NA|NA|NA	E	Belongs to the cysteine synthase cystathionine beta- synthase family
AHPHCOMF_01422	322159.STER_0405	6.3e-111	406.8	Bacilli	yvyE		3.4.13.9	ko:K01271					ko00000,ko01000,ko01002				Bacteria	1V6MQ@1239,4HBIT@91061,COG1739@1,COG1739@2	NA|NA|NA	S	YigZ family
AHPHCOMF_01423	322159.STER_0406	1.8e-253	881.3	Bacilli	comFA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576		ko:K02240		M00429			ko00000,ko00002,ko02044	3.A.11.1			Bacteria	1TPZE@1239,4HB00@91061,COG4098@1,COG4098@2	NA|NA|NA	L	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AHPHCOMF_01424	322159.STER_0407	4.4e-123	447.2	Bacilli	comFC			ko:K02242		M00429			ko00000,ko00002,ko02044				Bacteria	1V73S@1239,4HJ6R@91061,COG1040@1,COG1040@2	NA|NA|NA	S	Competence protein
AHPHCOMF_01425	322159.STER_0408	2.1e-94	351.7	Bacilli	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113		ko:K05808					ko00000,ko03009				Bacteria	1V1D5@1239,4HFX9@91061,COG1544@1,COG1544@2	NA|NA|NA	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AHPHCOMF_01433	322159.STER_0419	2.1e-166	591.7	Bacilli	ppaC	GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464	3.6.1.1	ko:K15986	ko00190,map00190				ko00000,ko00001,ko01000				Bacteria	1TPH6@1239,4H9T8@91061,COG1227@1,COG1227@2	NA|NA|NA	C	inorganic pyrophosphatase
AHPHCOMF_01434	264199.stu0373	6.4e-108	396.7	Bacilli													Bacteria	1W4V4@1239,2F8BM@1,340QP@2,4HR72@91061	NA|NA|NA	S	Domain of unknown function (DUF1803)
AHPHCOMF_01435	264199.stu0374	7.8e-102	376.3	Bacilli	ygaC			ko:K07586					ko00000				Bacteria	1TRX8@1239,4H9NM@91061,COG3557@1,COG3557@2	NA|NA|NA	J	Belongs to the UPF0374 family
AHPHCOMF_01436	264199.stu0375	2.8e-132	478.0	Bacilli	recX	GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019899,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496	2.4.1.337	ko:K03565,ko:K19002	ko00561,ko01100,map00561,map01100		R10850	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003,ko03400		GT4		Bacteria	1V72V@1239,4HKE3@91061,COG2137@1,COG2137@2	NA|NA|NA	S	Regulatory protein RecX
AHPHCOMF_01437	264199.stu0376	1.4e-259	901.7	Bacilli	rumA		2.1.1.190,2.1.1.35	ko:K00557,ko:K03215					ko00000,ko01000,ko03009,ko03016				Bacteria	1TP4H@1239,4HA6M@91061,COG2265@1,COG2265@2	NA|NA|NA	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AHPHCOMF_01438	322159.STER_0424	8e-193	679.5	Bacilli	asnA	GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230		R00483	RC00010	ko00000,ko00001,ko01000			iAPECO1_1312.APECO1_2719,iECOK1_1307.ECOK1_4193,iECS88_1305.ECS88_4166,iUMN146_1321.UM146_18910,iUTI89_1310.UTI89_C4299	Bacteria	1TP28@1239,4HAEC@91061,COG2502@1,COG2502@2	NA|NA|NA	E	aspartate--ammonia ligase
AHPHCOMF_01439	322159.STER_0425	2.4e-256	891.0	Bacilli	lysC	GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000			iYO844.BSU03790	Bacteria	1TPQJ@1239,4HAEP@91061,COG0527@1,COG0527@2	NA|NA|NA	E	Belongs to the aspartokinase family
AHPHCOMF_01440	322159.STER_0426	1.9e-115	421.8	Bacilli													Bacteria	1V7XM@1239,4IPJK@91061,COG0637@1,COG0637@2	NA|NA|NA	S	Haloacid dehalogenase-like hydrolase
AHPHCOMF_01441	264199.stu0380	2.4e-139	501.5	Bacilli	phaB	GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006635,GO:0006636,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009987,GO:0016042,GO:0016053,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0033559,GO:0034017,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:0072330,GO:1901575,GO:1901576	5.3.3.14,5.3.3.18	ko:K15866,ko:K18474	ko00061,ko00360,ko01120,map00061,map00360,map01120		R07639,R09837,R09839	RC00004,RC00326,RC01078,RC02689,RC03003	ko00000,ko00001,ko01000,ko01004				Bacteria	1TQ2V@1239,4HBT0@91061,COG1024@1,COG1024@2	NA|NA|NA	I	Belongs to the enoyl-CoA hydratase isomerase family
AHPHCOMF_01442	904306.HMPREF9192_0286	5.8e-71	273.5	Bacilli	marR												Bacteria	1V6GY@1239,4HIMR@91061,COG1846@1,COG1846@2	NA|NA|NA	K	Transcriptional regulator, MarR family
AHPHCOMF_01443	322159.STER_0429	2.3e-173	614.8	Bacilli	fabH		2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	1TP0K@1239,4HATK@91061,COG0332@1,COG0332@2	NA|NA|NA	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AHPHCOMF_01444	1046629.Ssal_01806	3.3e-30	137.1	Bacilli	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509		ko:K02078					ko00000,ko00001				Bacteria	1VGIY@1239,4HP0V@91061,COG0236@1,COG0236@2	NA|NA|NA	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AHPHCOMF_01445	264199.stu0385	5.8e-172	610.1	Bacilli	fabK		1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004			iHN637.CLJU_RS20775	Bacteria	1TPC3@1239,4H9T0@91061,COG2070@1,COG2070@2	NA|NA|NA	S	2-Nitropropane dioxygenase
AHPHCOMF_01446	264199.stu0386	8.5e-165	586.3	Bacilli	fabD		2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	1TPB7@1239,4HBCU@91061,COG0331@1,COG0331@2	NA|NA|NA	I	Malonyl CoA-acyl carrier protein transacylase
AHPHCOMF_01447	322159.STER_0433	1.6e-126	458.8	Bacilli													Bacteria	1TP76@1239,4HAA6@91061,COG1028@1,COG1028@2	NA|NA|NA	IQ	reductase
AHPHCOMF_01448	264199.stu0388	2.6e-233	814.3	Bacilli	fabF		2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	1TPA7@1239,4H9SD@91061,COG0304@1,COG0304@2	NA|NA|NA	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
AHPHCOMF_01449	322159.STER_0435	7.7e-56	223.4	Bacilli	accB		2.3.1.12,4.1.1.3	ko:K00627,ko:K01571,ko:K02160	ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00307,M00376	R00209,R00217,R00742,R02569	RC00004,RC00040,RC00367,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1			Bacteria	1VAB7@1239,4HKCS@91061,COG0511@1,COG0511@2	NA|NA|NA	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
AHPHCOMF_01450	1046629.Ssal_01800	1.5e-71	275.4	Bacilli	fabZ		3.5.1.108,4.2.1.59	ko:K02372,ko:K16363	ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212	M00060,M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005				Bacteria	1V6EX@1239,4HGX1@91061,COG0764@1,COG0764@2	NA|NA|NA	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
AHPHCOMF_01451	322159.STER_0437	4.8e-257	893.3	Bacilli	accC	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000			iSF_1195.SF3294	Bacteria	1TP16@1239,4HARK@91061,COG0439@1,COG0439@2	NA|NA|NA	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
AHPHCOMF_01452	264199.stu0392	1.6e-160	572.0	Bacilli	accD		2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP4U@1239,4HAI7@91061,COG0777@1,COG0777@2	NA|NA|NA	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AHPHCOMF_01453	322159.STER_0439	2e-138	498.4	Bacilli	accA		2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000				Bacteria	1UHNS@1239,4HA4C@91061,COG0825@1,COG0825@2	NA|NA|NA	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
AHPHCOMF_01454	1046629.Ssal_01795	4.7e-90	337.0	Bacilli	luxS	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009116,GO:0009119,GO:0009372,GO:0009987,GO:0010699,GO:0016053,GO:0016829,GO:0016846,GO:0017144,GO:0019284,GO:0019752,GO:0023052,GO:0033353,GO:0034641,GO:0042278,GO:0043094,GO:0043102,GO:0043436,GO:0043768,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046128,GO:0046394,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0051704,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000			iECIAI39_1322.ECIAI39_2877,iPC815.YPO3300	Bacteria	1V1V3@1239,4HFR0@91061,COG1854@1,COG1854@2	NA|NA|NA	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
AHPHCOMF_01455	264199.stu0396	5.2e-65	253.4	Bacilli	tnp			ko:K07498					ko00000				Bacteria	1TTKR@1239,4HCB4@91061,COG3316@1,COG3316@2	NA|NA|NA	L	Transposase
AHPHCOMF_01456	264199.stu0397	8.1e-203	713.4	Bacilli	rny	GO:0003674,GO:0005488,GO:0005515,GO:0042802		ko:K05802,ko:K18682	ko03018,map03018				ko00000,ko00001,ko01000,ko02000,ko03019	1.A.23.1.1			Bacteria	1TP48@1239,4HC9J@91061,COG1418@1,COG1418@2,COG4372@1,COG4372@2	NA|NA|NA	D	Endoribonuclease that initiates mRNA decay
AHPHCOMF_01457	264199.stu0398	6.8e-84	316.6	Firmicutes				ko:K07485					ko00000				Bacteria	1TQ93@1239,COG3464@1,COG3464@2	NA|NA|NA	L	Transposase
AHPHCOMF_01458	322159.STER_0444	5.6e-114	417.2	Bacilli	fruR			ko:K03436					ko00000,ko03000				Bacteria	1TSF8@1239,4HDT9@91061,COG1349@1,COG1349@2	NA|NA|NA	K	transcriptional
AHPHCOMF_01459	264199.stu0400	2.1e-163	581.6	Bacilli	pfkB		2.7.1.11,2.7.1.56	ko:K00882,ko:K16370	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00345	R00756,R02071,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQ36@1239,4HANU@91061,COG1105@1,COG1105@2	NA|NA|NA	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
AHPHCOMF_01460	264199.stu0401	3.9e-54	217.2	Bacilli	fruA		2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1			Bacteria	1UJ3M@1239,4IT0X@91061,COG1445@1,COG1445@2,COG1762@1,COG1762@2	NA|NA|NA	GT	PTS system, Lactose/Cellobiose specific IIB subunit
AHPHCOMF_01461	264199.stu0401	2.2e-49	201.4	Bacilli	fruA		2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1			Bacteria	1UJ3M@1239,4IT0X@91061,COG1445@1,COG1445@2,COG1762@1,COG1762@2	NA|NA|NA	GT	PTS system, Lactose/Cellobiose specific IIB subunit
AHPHCOMF_01462	1046629.Ssal_01791	2.7e-126	458.4	Bacilli	fruA		2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1			Bacteria	1TPKU@1239,4H9KR@91061,COG1299@1,COG1299@2,COG1445@1,COG1445@2,COG1762@1,COG1762@2	NA|NA|NA	G	phosphotransferase system
AHPHCOMF_01463	264199.stu0407	1.2e-34	152.1	Bacilli	fruA		2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1			Bacteria	1TPKU@1239,4H9KR@91061,COG1299@1,COG1299@2	NA|NA|NA	G	phosphotransferase system
AHPHCOMF_01464	322159.STER_0447	2.1e-260	904.4	Bacilli	gor	GO:0000166,GO:0003674,GO:0003824,GO:0004362,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0015037,GO:0015038,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071949,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918		R00094,R00115	RC00011	ko00000,ko00001,ko01000			iZ_1308.Z4900	Bacteria	1TQFH@1239,4HCT8@91061,COG1249@1,COG1249@2	NA|NA|NA	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AHPHCOMF_01465	264199.stu0409	2.4e-242	844.3	Bacilli	folC		6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000			iLJ478.TM0166	Bacteria	1TPX5@1239,4HBJM@91061,COG0285@1,COG0285@2	NA|NA|NA	H	Belongs to the folylpolyglutamate synthase family
AHPHCOMF_01467	264199.stu0411	6.1e-213	746.5	Bacilli	iscS2		2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122		R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029				Bacteria	1TP21@1239,4HAEE@91061,COG1104@1,COG1104@2	NA|NA|NA	E	Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
AHPHCOMF_01468	322159.STER_0451	2.9e-229	800.8	Bacilli	thiI	GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122		R07461		ko00000,ko00001,ko01000,ko03016			iECNA114_1301.ECNA114_0400,iECO26_1355.ECO26_0455,iECSF_1327.ECSF_0383,iSDY_1059.SDY_0307	Bacteria	1TPNW@1239,4HAV9@91061,COG0301@1,COG0301@2	NA|NA|NA	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AHPHCOMF_01469	322159.STER_0452	3.2e-294	1016.9	Bacilli	gtf1		2.4.1.52	ko:K00712					ko00000,ko01000,ko01003		GT4		Bacteria	1TR6K@1239,4HGDG@91061,COG0438@1,COG0438@2	NA|NA|NA	M	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
AHPHCOMF_01470	322159.STER_0453	7.2e-258	896.0	Firmicutes	gtf2												Bacteria	1TQZR@1239,COG0438@1,COG0438@2	NA|NA|NA	M	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
AHPHCOMF_01471	1046629.Ssal_01780	6.4e-29	132.9	Bacteria			2.3.1.128	ko:K03789					ko00000,ko01000,ko03009				Bacteria	COG0454@1,COG0456@2	NA|NA|NA	K	acetyltransferase
AHPHCOMF_01472	264199.stu0417	4.5e-49	200.3	Bacilli	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02888	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V9YH@1239,4HIGK@91061,COG0261@1,COG0261@2	NA|NA|NA	J	This protein binds to 23S rRNA in the presence of protein L20
AHPHCOMF_01473	1046629.Ssal_01778	1.5e-46	191.8	Bacilli	rpmA	GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904		ko:K02899	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V6HW@1239,4HIMN@91061,COG0211@1,COG0211@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL27 family
AHPHCOMF_01474	322159.STER_0457	2e-126	458.4	Bacteria	ydaF_2												Bacteria	COG1670@1,COG1670@2	NA|NA|NA	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AHPHCOMF_01475	322159.STER_0458	2.6e-64	251.1	Bacilli	WQ51_03320												Bacteria	1VHA6@1239,4HPTC@91061,COG4835@1,COG4835@2	NA|NA|NA	S	cog cog4835
AHPHCOMF_01476	904306.HMPREF9192_0332	6.4e-61	240.0	Bacilli	XK27_08360												Bacteria	1TRM7@1239,4HVKJ@91061,COG1307@1,COG1307@2	NA|NA|NA	S	EDD domain protein, DegV family
AHPHCOMF_01477	904306.HMPREF9192_0332	2.1e-74	285.0	Bacilli	XK27_08360												Bacteria	1TRM7@1239,4HVKJ@91061,COG1307@1,COG1307@2	NA|NA|NA	S	EDD domain protein, DegV family
AHPHCOMF_01478	264199.stu0424	4.3e-138	497.3	Bacilli	dapB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0070402,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000			iJN678.dapB,iNJ661.Rv2773c,iYO844.BSU22490	Bacteria	1TR9D@1239,4HA5X@91061,COG0289@1,COG0289@2	NA|NA|NA	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
AHPHCOMF_01479	264199.stu0425	9e-223	779.2	Bacilli	cca		2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018		R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019				Bacteria	1TQ2A@1239,4HB2W@91061,COG0617@1,COG0617@2	NA|NA|NA	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AHPHCOMF_01480	322159.STER_0462	0.0	1191.8	Bacilli	yfmR			ko:K15738					ko00000,ko02000	3.A.1.120.6			Bacteria	1TPAX@1239,4H9TK@91061,COG0488@1,COG0488@2	NA|NA|NA	S	abc transporter atp-binding protein
AHPHCOMF_01481	1123298.KB904062_gene886	3.3e-25	121.7	Bacteria													Bacteria	COG3247@1,COG3247@2	NA|NA|NA	U	response to pH
AHPHCOMF_01482	322159.STER_0465	1e-139	502.7	Bacilli			3.6.1.13,3.6.1.55	ko:K01515,ko:K03574	ko00230,map00230		R01054	RC00002	ko00000,ko00001,ko01000,ko03400				Bacteria	1TST7@1239,4HEFP@91061,COG1051@1,COG1051@2	NA|NA|NA	F	AdP-ribose pyrophosphatase
AHPHCOMF_01483	264199.stu0429	3.8e-212	743.8	Bacilli	nadD		2.7.1.22,2.7.7.1,2.7.7.18,3.6.1.55	ko:K00969,ko:K03574,ko:K06211	ko00760,ko01100,map00760,map01100	M00115	R00137,R02324,R03005	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko03000,ko03400			iIT341.HP1337	Bacteria	1TQ29@1239,4HBZT@91061,COG1057@1,COG1057@2,COG3172@1,COG3172@2	NA|NA|NA	H	adenylyltransferase
AHPHCOMF_01484	264199.stu0430	1.8e-256	891.3	Bacilli	gdhA		1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100		R00248	RC00006,RC02799	ko00000,ko00001,ko01000				Bacteria	1TP45@1239,4HAEI@91061,COG0334@1,COG0334@2	NA|NA|NA	E	Belongs to the Glu Leu Phe Val dehydrogenases family
AHPHCOMF_01485	322159.STER_0468	1e-69	269.2	Bacilli	def_1		3.5.1.31,3.5.1.88	ko:K01450,ko:K01462	ko00270,ko00630,map00270,map00630		R00653	RC00165,RC00323	ko00000,ko00001,ko01000				Bacteria	1V73T@1239,4HGYC@91061,COG0242@1,COG0242@2	NA|NA|NA	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins
AHPHCOMF_01486	264199.stu0432	1.9e-77	295.0	Bacteria													Bacteria	COG1846@1,COG1846@2	NA|NA|NA	K	DNA-binding transcription factor activity
AHPHCOMF_01487	322159.STER_0470	0.0	1080.1	Bacilli	lmrA1			ko:K02021,ko:K06147,ko:K06148,ko:K18887	ko02010,map02010	M00706			ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21			Bacteria	1TP0B@1239,4H9SC@91061,COG1132@1,COG1132@2	NA|NA|NA	V	abc transporter atp-binding protein
AHPHCOMF_01488	264199.stu0434	0.0	1124.8	Bacilli	lmrA2			ko:K06147					ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21			Bacteria	1TP0B@1239,4HA3S@91061,COG1132@1,COG1132@2	NA|NA|NA	V	abc transporter atp-binding protein
AHPHCOMF_01489	1046629.Ssal_01762	5.4e-45	186.8	Bacilli													Bacteria	1VF01@1239,4HPKN@91061,COG0454@1,COG0456@2	NA|NA|NA	K	Acetyltransferase (GNAT) family
AHPHCOMF_01490	264199.stu0437	3.2e-78	297.7	Bacilli	sptS		2.7.13.3	ko:K11328	ko02020,map02020	M00464			ko00000,ko00001,ko00002,ko01000,ko01001,ko02022				Bacteria	1UHQH@1239,4HAHG@91061,COG0642@1,COG0642@2	NA|NA|NA	T	Histidine kinase
AHPHCOMF_01491	322159.STER_0474	4.9e-131	473.8	Bacilli	pyrH	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100		R00158	RC00002	ko00000,ko00001,ko01000			iSB619.SA_RS06240	Bacteria	1TPXN@1239,4H9UB@91061,COG0528@1,COG0528@2	NA|NA|NA	F	Catalyzes the reversible phosphorylation of UMP to UDP
AHPHCOMF_01492	322159.STER_0475	1.3e-91	342.4	Bacilli	frr	GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576		ko:K02838					ko00000,ko03012				Bacteria	1V1F2@1239,4HFSH@91061,COG0233@1,COG0233@2	NA|NA|NA	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
AHPHCOMF_01493	322159.STER_0476	5.3e-161	573.5	Bacilli	cvfB			ko:K00243					ko00000				Bacteria	1TQ1Z@1239,4HDAZ@91061,COG2996@1,COG2996@2	NA|NA|NA	S	Protein conserved in bacteria
AHPHCOMF_01494	264199.stu0441	7.4e-35	152.5	Bacilli	yozE												Bacteria	1VFI4@1239,4HR7P@91061,COG4479@1,COG4479@2	NA|NA|NA	S	Belongs to the UPF0346 family
AHPHCOMF_01495	322159.STER_0478	2.2e-130	472.6	Bacteria	usp		3.5.1.104,3.5.1.28	ko:K15125,ko:K17733,ko:K21449,ko:K21471,ko:K22278,ko:K22409	ko05133,map05133				ko00000,ko00001,ko00536,ko01000,ko01002,ko01011,ko02000	1.B.40.2	CBM50		Bacteria	COG1388@1,COG1388@2,COG3942@1,COG3942@2	NA|NA|NA	S	pathogenesis
AHPHCOMF_01496	264199.stu0446	2.3e-61	241.9	Bacilli	rlpA			ko:K03642					ko00000				Bacteria	1V61Q@1239,4HHT0@91061,COG1388@1,COG1388@2	NA|NA|NA	M	LysM domain protein
AHPHCOMF_01497	322159.STER_0480	8e-191	672.9	Bacilli	phoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K06217					ko00000				Bacteria	1TP35@1239,4HBD5@91061,COG1702@1,COG1702@2	NA|NA|NA	T	phosphate starvation-inducible protein PhoH
AHPHCOMF_01501	264199.stu0451	0.0	1344.3	Bacilli	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10,6.1.1.20	ko:K01874,ko:K01890,ko:K06878	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R03660,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1TPA1@1239,4H9VC@91061,COG0073@1,COG0073@2,COG0143@1,COG0143@2	NA|NA|NA	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AHPHCOMF_01502	904306.HMPREF9192_0361	9.2e-164	582.8	Bacilli													Bacteria	1V53I@1239,4HIEU@91061,COG0583@1,COG0583@2	NA|NA|NA	K	transcriptional regulator (lysR family)
AHPHCOMF_01503	322159.STER_0488	1.4e-186	658.7	Bacilli	coiA		3.6.4.12	ko:K03657,ko:K06198	ko03420,ko03430,map03420,map03430				ko00000,ko00001,ko01000,ko03400				Bacteria	1TRGD@1239,4HFP5@91061,COG4469@1,COG4469@2	NA|NA|NA	S	Competence protein
AHPHCOMF_01504	264199.stu0454	0.0	1196.8	Bacilli	pepF	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564		ko:K08602					ko00000,ko01000,ko01002				Bacteria	1TP4P@1239,4HA7X@91061,COG1164@1,COG1164@2	NA|NA|NA	E	oligoendopeptidase F
AHPHCOMF_01505	264199.stu0455	5.4e-127	460.3	Bacilli	yrrM		2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000				Bacteria	1UF4M@1239,4HE9E@91061,COG4122@1,COG4122@2	NA|NA|NA	S	O-Methyltransferase
AHPHCOMF_01506	322159.STER_0492	4.6e-168	597.4	Bacteria	prsA		3.1.3.16,5.2.1.8	ko:K01802,ko:K03769,ko:K07533,ko:K20074					ko00000,ko01000,ko01009,ko03110				Bacteria	COG0760@1,COG0760@2	NA|NA|NA	O	peptidyl-prolyl cis-trans isomerase activity
AHPHCOMF_01507	264199.stu0457	0.0	1720.3	Bacilli	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1TPK6@1239,4H9XC@91061,COG0013@1,COG0013@2	NA|NA|NA	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AHPHCOMF_01508	1046629.Ssal_01709	7.9e-24	115.9	Bacilli			3.4.17.14,3.5.1.28	ko:K01448,ko:K02395,ko:K07260	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	M00651,M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036				Bacteria	1W25V@1239,4HGXW@91061,COG0860@1,COG0860@2,COG1705@1,COG1705@2	NA|NA|NA	M	GBS Bsp-like repeat
AHPHCOMF_01509	322159.STER_0495	6.9e-179	633.3	Bacilli			3.4.17.14,3.5.1.28	ko:K01448,ko:K07260,ko:K21471	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	M00651,M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko03036				Bacteria	1W25V@1239,4HGXW@91061,COG0860@1,COG0860@2,COG3942@1,COG3942@2	NA|NA|NA	M	GBS Bsp-like repeat
AHPHCOMF_01510	264199.stu0461	5.6e-119	434.1	Bacteria			3.4.17.14,3.5.1.28	ko:K01448,ko:K02395,ko:K07260	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	M00651,M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036				Bacteria	COG1705@1,COG1705@2	NA|NA|NA	NU	amidase activity
AHPHCOMF_01511	264199.stu0462	4.9e-145	520.4	Bacilli	cnhA		3.5.1.3	ko:K11206,ko:K13566	ko00250,map00250		R00269,R00348	RC00010	ko00000,ko00001,ko01000				Bacteria	1TQDK@1239,4HC44@91061,COG0388@1,COG0388@2	NA|NA|NA	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
AHPHCOMF_01512	322159.STER_0499	5.3e-228	796.6	Bacilli	mtnE		2.6.1.83	ko:K08969,ko:K10206	ko00270,ko00300,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map01100,map01110,map01130,map01230	M00034,M00527	R07396,R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	1TQD6@1239,4HAHQ@91061,COG0436@1,COG0436@2	NA|NA|NA	E	mutations do not affect methionine salvage in vivo however
AHPHCOMF_01513	322159.STER_0500	1.5e-191	675.2	Bacilli	argC	GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000			iLJ478.TM1782,iSSON_1240.SSON_4131,iYO844.BSU11190	Bacteria	1TPVI@1239,4H9YD@91061,COG0002@1,COG0002@2	NA|NA|NA	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AHPHCOMF_01514	264199.stu0465	8.6e-210	736.1	Bacilli	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35,2.7.2.8	ko:K00620,ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282,R02649	RC00002,RC00004,RC00043,RC00064	ko00000,ko00001,ko00002,ko01000			iLJ478.TM1783	Bacteria	1TPBP@1239,4H9TQ@91061,COG1364@1,COG1364@2	NA|NA|NA	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AHPHCOMF_01515	264199.stu0466	2.1e-129	468.4	Firmicutes	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP0N@1239,COG0548@1,COG0548@2	NA|NA|NA	E	Belongs to the acetylglutamate kinase family. ArgB subfamily
AHPHCOMF_01516	322159.STER_0503	9e-209	732.6	Bacilli	argD	GO:0003674,GO:0003824,GO:0003992,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	1TP9S@1239,4H9VZ@91061,COG4992@1,COG4992@2	NA|NA|NA	E	acetylornithine aminotransferase
AHPHCOMF_01517	322159.STER_0504	3.7e-140	504.2	Bacilli	yxkH												Bacteria	1V6AW@1239,4HHC9@91061,COG0726@1,COG0726@2	NA|NA|NA	G	deacetylase
AHPHCOMF_01518	322159.STER_0506	1.8e-237	828.2	Bacilli	hom	GO:0003674,GO:0003824,GO:0004412,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000			iNJ661.Rv1294,iSB619.SA_RS06610	Bacteria	1TQ2H@1239,4HBAP@91061,COG0460@1,COG0460@2	NA|NA|NA	E	homoserine dehydrogenase
AHPHCOMF_01519	322159.STER_0507	1.1e-153	549.3	Bacilli	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000			iECSE_1348.ECSE_0003,iJN678.thrB,iLJ478.TM0545	Bacteria	1TRWS@1239,4HCQN@91061,COG0083@1,COG0083@2	NA|NA|NA	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
AHPHCOMF_01520	322159.STER_0508	5.5e-153	547.0	Bacilli	rarD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944		ko:K05786					ko00000,ko02000	2.A.7.7			Bacteria	1TQF2@1239,4HAYU@91061,COG2962@1,COG2962@2	NA|NA|NA	S	Transporter
AHPHCOMF_01521	1123315.AUIP01000020_gene2219	2.2e-15	89.4	Bacteria													Bacteria	COG3212@1,COG3212@2	NA|NA|NA	T	peptidase
AHPHCOMF_01522	1123314.AUIO01000005_gene141	8.9e-14	82.4	Bacilli	coiA		3.6.4.12	ko:K03657,ko:K06198	ko03420,ko03430,map03420,map03430				ko00000,ko00001,ko01000,ko03400				Bacteria	1TRGD@1239,4HFP5@91061,COG4469@1,COG4469@2	NA|NA|NA	S	Competence protein
AHPHCOMF_01523	322159.STER_0511	4.1e-112	410.6	Bacilli													Bacteria	1VENC@1239,4HQ31@91061,COG1853@1,COG1853@2	NA|NA|NA	S	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AHPHCOMF_01524	264199.stu0476	1.9e-46	191.4	Bacteria			2.3.1.128,5.2.1.8	ko:K03768,ko:K03790					ko00000,ko01000,ko03009,ko03110				Bacteria	COG1670@1,COG1670@2	NA|NA|NA	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AHPHCOMF_01525	322159.STER_0513	0.0	1749.6	Bacilli	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iLJ478.TM1817	Bacteria	1TPN4@1239,4HB85@91061,COG0525@1,COG0525@2	NA|NA|NA	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
AHPHCOMF_01526	1123298.KB904069_gene1213	3.2e-16	90.5	Bacteria	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600		ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194	3.A.2.1			Bacteria	2ZI0B@2,COG0636@1	NA|NA|NA	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AHPHCOMF_01527	322159.STER_0516	4.3e-124	450.7	Bacilli	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600		ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1		iAPECO1_1312.APECO1_2725,iE2348C_1286.E2348C_4048,iEC042_1314.EC042_4125,iECABU_c1320.ECABU_c42230,iECED1_1282.ECED1_4428,iECIAI39_1322.ECIAI39_4342,iECNA114_1301.ECNA114_3887,iECOK1_1307.ECOK1_4187,iECP_1309.ECP_3937,iECS88_1305.ECS88_4160,iECSF_1327.ECSF_3586,iECUMN_1333.ECUMN_4268,iEcSMS35_1347.EcSMS35_4106,iLF82_1304.LF82_0192,iNRG857_1313.NRG857_18615,iUMN146_1321.UM146_18880,iUMNK88_1353.UMNK88_4550,iUTI89_1310.UTI89_C4293,ic_1306.c4666	Bacteria	1TQIT@1239,4H9NV@91061,COG0356@1,COG0356@2	NA|NA|NA	C	it plays a direct role in the translocation of protons across the membrane
AHPHCOMF_01528	264199.stu0480	3.3e-78	297.7	Firmicutes	atpF			ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194	3.A.2.1		iHN637.CLJU_RS01170,iYO844.BSU36850	Bacteria	1V74A@1239,COG0711@1,COG0711@2	NA|NA|NA	C	ATP synthase F(0) sector subunit b
AHPHCOMF_01529	264199.stu0481	9.3e-87	326.2	Bacilli	atpH	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600		ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194	3.A.2.1		iSF_1195.SF3815,iSFxv_1172.SFxv_4157,iS_1188.S3953	Bacteria	1VAG3@1239,4HKW1@91061,COG0712@1,COG0712@2	NA|NA|NA	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AHPHCOMF_01530	264199.stu0482	3.8e-279	966.8	Bacilli	atpA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1		iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187	Bacteria	1TNZ8@1239,4HAMZ@91061,COG0056@1,COG0056@2	NA|NA|NA	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AHPHCOMF_01531	264199.stu0483	2.5e-158	564.7	Bacilli	atpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194	3.A.2.1		iLJ478.TM1611,iSB619.SA_RS10970,iYO844.BSU36820	Bacteria	1TPBX@1239,4HB0E@91061,COG0224@1,COG0224@2	NA|NA|NA	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AHPHCOMF_01532	322159.STER_0521	2.7e-263	914.1	Bacilli	atpD		3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1		iSB619.SA_RS10965	Bacteria	1TPGF@1239,4HAT6@91061,COG0055@1,COG0055@2	NA|NA|NA	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AHPHCOMF_01533	322159.STER_0522	2e-66	258.5	Bacilli	atpC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600		ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194	3.A.2.1		iJN746.PP_5412,iSbBS512_1146.SbBS512_E4190	Bacteria	1VA89@1239,4HKHS@91061,COG0355@1,COG0355@2	NA|NA|NA	C	Produces ATP from ADP in the presence of a proton gradient across the membrane
AHPHCOMF_01534	264199.stu0486	2.8e-230	804.3	Bacilli	ftsW			ko:K03588	ko04112,map04112				ko00000,ko00001,ko02000,ko03036	2.A.103.1			Bacteria	1TPT7@1239,4HAEV@91061,COG0772@1,COG0772@2	NA|NA|NA	D	Belongs to the SEDS family
AHPHCOMF_01535	264199.stu0487	9.5e-225	785.8	Bacilli	tuf	GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009274,GO:0009275,GO:0009986,GO:0010339,GO:0016020,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035821,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484		ko:K02358,ko:K15771	ko02010,map02010	M00491			ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	3.A.1.1.16,3.A.1.1.2			Bacteria	1TPKC@1239,4HAEH@91061,COG0050@1,COG0050@2	NA|NA|NA	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AHPHCOMF_01536	264199.stu0488	1.4e-136	492.3	Bacilli	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147			iHN637.CLJU_RS19265	Bacteria	1TP2F@1239,4HAPT@91061,COG0149@1,COG0149@2	NA|NA|NA	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
AHPHCOMF_01537	264199.stu0489	1.1e-110	406.0	Bacilli	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000			iSB619.SA_RS02535	Bacteria	1V1HE@1239,4HGWR@91061,COG0125@1,COG0125@2	NA|NA|NA	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AHPHCOMF_01538	264199.stu0490	6.4e-162	576.6	Bacilli	holB		2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1TRVS@1239,4HA3T@91061,COG0470@1,COG0470@2	NA|NA|NA	L	dna polymerase iii
AHPHCOMF_01539	322159.STER_0528	1.2e-135	489.2	Bacilli	yaaT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464											Bacteria	1TP1V@1239,4H9M9@91061,COG1774@1,COG1774@2	NA|NA|NA	S	stage 0 sporulation protein
AHPHCOMF_01540	264199.stu0492	9.5e-55	219.2	Bacilli	yabA	GO:0003674,GO:0005488,GO:0005515,GO:0042802											Bacteria	1VA1F@1239,4HKND@91061,COG4467@1,COG4467@2	NA|NA|NA	L	Involved in initiation control of chromosome replication
AHPHCOMF_01541	264199.stu0493	2.7e-160	571.2	Bacilli	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.198	ko:K07056					ko00000,ko01000,ko03009				Bacteria	1TP6U@1239,4HAH8@91061,COG0313@1,COG0313@2	NA|NA|NA	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AHPHCOMF_01542	322159.STER_0531	5.2e-226	790.0	Bacilli	amt			ko:K03320					ko00000,ko02000	1.A.11			Bacteria	1TQYG@1239,4HBGK@91061,COG0004@1,COG0004@2	NA|NA|NA	P	Ammonium Transporter
AHPHCOMF_01543	322159.STER_0532	1.1e-53	215.7	Firmicutes	glnB			ko:K04751,ko:K04752	ko02020,map02020				ko00000,ko00001				Bacteria	1V9Z5@1239,COG0347@1,COG0347@2	NA|NA|NA	K	Belongs to the P(II) protein family
AHPHCOMF_01544	322159.STER_0533	4.9e-106	390.6	Firmicutes	mur1			ko:K02395					ko00000,ko02035				Bacteria	1UYRM@1239,COG1705@1,COG1705@2	NA|NA|NA	NU	mannosyl-glycoprotein
AHPHCOMF_01545	322159.STER_0534	5.8e-149	533.5	Bacilli	XK27_04800												Bacteria	1VAFW@1239,4HIFQ@91061,COG0561@1,COG0561@2	NA|NA|NA	S	Sucrose-6F-phosphate phosphohydrolase
AHPHCOMF_01546	264199.stu0499	2.1e-68	265.0	Bacteria	nptA			ko:K03324					ko00000,ko02000	2.A.58.2			Bacteria	COG1283@1,COG1283@2	NA|NA|NA	P	sodium-dependent phosphate transmembrane transporter activity
AHPHCOMF_01547	322159.STER_0537	3.6e-221	773.9	Bacilli	nagA		3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130		R02059	RC00166,RC00300	ko00000,ko00001,ko01000				Bacteria	1TPFK@1239,4HC6C@91061,COG1820@1,COG1820@2	NA|NA|NA	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AHPHCOMF_01548	264199.stu0502	1.8e-53	214.9	Bacteria													Bacteria	COG3949@1,COG3949@2	NA|NA|NA		
AHPHCOMF_01549	264199.stu0503	7.5e-26	122.5	Bacteria													Bacteria	COG3949@1,COG3949@2	NA|NA|NA		
AHPHCOMF_01550	264199.stu0504	1.5e-59	235.3	Bacteria													Bacteria	COG3949@1,COG3949@2	NA|NA|NA		
AHPHCOMF_01551	904306.HMPREF9192_0417	6.1e-63	246.9	Bacilli													Bacteria	1U601@1239,4HBYW@91061,COG3949@1,COG3949@2	NA|NA|NA	S	membrane
AHPHCOMF_01552	264199.stu0505	4.8e-176	623.6	Bacilli	glyQ	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016875,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01878,ko:K14164	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iAF1260.b3560,iAF987.Gmet_2942,iJO1366.b3560,iPC815.YPO4072,iY75_1357.Y75_RS19360	Bacteria	1TPW8@1239,4HBCF@91061,COG0752@1,COG0752@2	NA|NA|NA	J	glycyl-tRNA synthetase alpha subunit
AHPHCOMF_01553	322159.STER_0540	0.0	1291.6	Bacilli	glyS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01879,ko:K14164	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iAPECO1_1312.APECO1_2891,iE2348C_1286.E2348C_3810,iECABU_c1320.ECABU_c40010,iECED1_1282.ECED1_4242,iECH74115_1262.ECH74115_4934,iECNA114_1301.ECNA114_3710,iECOK1_1307.ECOK1_4005,iECP_1309.ECP_3661,iECS88_1305.ECS88_3976,iECSF_1327.ECSF_3393,iECSP_1301.ECSP_4554,iECs_1301.ECs4442,iG2583_1286.G2583_4300,iJN678.glyS,iUMN146_1321.UM146_17960,iUTI89_1310.UTI89_C4099,ic_1306.c4378	Bacteria	1TNZ7@1239,4H9NT@91061,COG0751@1,COG0751@2	NA|NA|NA	J	Glycyl-tRNA synthetase beta subunit
AHPHCOMF_01554	322159.STER_0541	4.5e-39	166.8	Bacilli	ynzC												Bacteria	1VEKJ@1239,4HNIB@91061,COG4224@1,COG4224@2	NA|NA|NA	S	UPF0291 protein
AHPHCOMF_01555	264199.stu0509	1.8e-254	884.8	Bacilli	cycA	GO:0001761,GO:0001762,GO:0003333,GO:0003674,GO:0005215,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015180,GO:0015187,GO:0015238,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015808,GO:0015816,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0022858,GO:0022889,GO:0032328,GO:0032329,GO:0034220,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0042940,GO:0042941,GO:0042942,GO:0042943,GO:0042944,GO:0042945,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039		ko:K03293,ko:K11737					ko00000,ko02000	2.A.3.1,2.A.3.1.7		iECO111_1330.ECO111_5093,iECO26_1355.ECO26_5376,iEcHS_1320.EcHS_A4458,iSbBS512_1146.SbBS512_E4749,iYL1228.KPN_04601	Bacteria	1TP97@1239,4H9QX@91061,COG1113@1,COG1113@2	NA|NA|NA	E	permease
AHPHCOMF_01556	585202.SMSK321_1723	1.1e-09	70.5	Streptococcus mitis	uvrX		2.7.7.7	ko:K02346,ko:K03502,ko:K14161					ko00000,ko01000,ko03400				Bacteria	1TP42@1239,2TNV1@28037,4HA1P@91061,COG0389@1,COG0389@2	NA|NA|NA	L	ImpB mucB samB family
AHPHCOMF_01557	264199.stu0511	1.5e-25	121.3	Bacteria			2.7.1.208,2.7.1.211	ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02808,ko:K02809,ko:K02810,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	M00265,M00266,M00268,M00269,M00270,M00271,M00272,M00303,M00806	R00811,R02738,R02780,R04111,R04394,R05132,R08559	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1,4.A.1.1.11,4.A.1.1.12,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9			Bacteria	COG1264@1,COG1264@2	NA|NA|NA	G	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AHPHCOMF_01558	264199.stu0512	1.4e-47	195.3	Bacilli	pts33BCA			ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	M00271			ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6			Bacteria	1TP5X@1239,4HA0I@91061,COG1263@1,COG1263@2	NA|NA|NA	G	pts system
AHPHCOMF_01559	264199.stu0513	4.2e-119	434.1	Bacilli	pts33BCA			ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	M00271			ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6			Bacteria	1TP5X@1239,4HA0I@91061,COG1263@1,COG1263@2	NA|NA|NA	G	pts system
AHPHCOMF_01560	264199.stu0514	3.3e-77	294.3	Bacilli			2.7.1.199,2.7.1.211	ko:K02755,ko:K02756,ko:K02757,ko:K02808,ko:K02809,ko:K02810,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060	M00269,M00271,M00809	R00811,R02738	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.13,4.A.1.1.14,4.A.1.1.9,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9			Bacteria	1W092@1239,4ISC3@91061,COG2190@1,COG2190@2	NA|NA|NA	G	PTS glucose transporter subunit IIA
AHPHCOMF_01561	322159.STER_0545	1.6e-140	505.4	Bacteria	ppiA		5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217				ko00000,ko00001,ko01000,ko03110,ko04147				Bacteria	COG0652@1,COG0652@2	NA|NA|NA	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AHPHCOMF_01566	322159.STER_0552	1.8e-167	595.1	Bacilli	fhuR												Bacteria	1V53I@1239,4HIEU@91061,COG0583@1,COG0583@2	NA|NA|NA	K	transcriptional regulator (lysR family)
AHPHCOMF_01567	322159.STER_0553	8.8e-78	296.2	Bacilli	lspA		3.4.23.36	ko:K03101	ko03060,map03060				ko00000,ko00001,ko01000,ko01002				Bacteria	1VA9R@1239,4HIR4@91061,COG0597@1,COG0597@2	NA|NA|NA	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AHPHCOMF_01568	322159.STER_0554	5e-162	577.0	Bacilli	rluD	GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180					ko00000,ko01000,ko03009			iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432	Bacteria	1TPCM@1239,4HBG2@91061,COG0564@1,COG0564@2	NA|NA|NA	J	Responsible for synthesis of pseudouridine from uracil
AHPHCOMF_01569	264199.stu0523	4e-87	327.4	Bacilli	pyrR		2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100		R00966	RC00063	ko00000,ko00001,ko01000,ko03000				Bacteria	1V3GV@1239,4HGYE@91061,COG2065@1,COG2065@2	NA|NA|NA	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AHPHCOMF_01570	322159.STER_0556	4.9e-227	793.5	Bacilli	pyrP			ko:K02824					ko00000,ko02000	2.A.40.1.1,2.A.40.1.2		iLJ478.TM0819	Bacteria	1TQKX@1239,4HAEU@91061,COG2233@1,COG2233@2	NA|NA|NA	F	uracil Permease
AHPHCOMF_01571	264199.stu0525	1e-173	615.9	Bacilli	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00608,ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000			iYO844.BSU15490	Bacteria	1TQ96@1239,4H9M6@91061,COG0540@1,COG0540@2	NA|NA|NA	F	Belongs to the ATCase OTCase family
AHPHCOMF_01572	322159.STER_0558	1.1e-211	742.3	Bacilli	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01955,ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000			iNJ661.Rv1383,iYO844.BSU15510	Bacteria	1TQ8N@1239,4H9Z0@91061,COG0505@1,COG0505@2	NA|NA|NA	F	carbamoyl-phosphate synthetase glutamine chain
AHPHCOMF_01573	264199.stu0527	0.0	2065.0	Bacilli	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPID@1239,4HAEY@91061,COG0458@1,COG0458@2	NA|NA|NA	F	carbamoyl-phosphate synthetase ammonia chain
AHPHCOMF_01574	322159.STER_0561	6.4e-134	483.4	Bacilli			2.1.1.223	ko:K15460					ko00000,ko01000,ko03016				Bacteria	1UJ4P@1239,4IT17@91061,COG4123@1,COG4123@2	NA|NA|NA	S	Putative SAM-dependent methyltransferase
AHPHCOMF_01575	904306.HMPREF9192_0439	4.4e-30	137.5	Bacteria	acrA	GO:0003674,GO:0005488,GO:0005515,GO:0042802		ko:K02005					ko00000				Bacteria	COG0845@1,COG0845@2	NA|NA|NA	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AHPHCOMF_01576	264199.stu0532	3.6e-35	153.7	Bacteria													Bacteria	COG0577@1,COG0577@2	NA|NA|NA	V	efflux transmembrane transporter activity
AHPHCOMF_01577	264199.stu0533	3.1e-31	141.0	Bacteria				ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	COG0577@1,COG0577@2	NA|NA|NA	V	efflux transmembrane transporter activity
AHPHCOMF_01578	264199.stu0535	1.2e-26	125.2	Bacteria	ytrF			ko:K02004,ko:K16918	ko02010,map02010	M00258,M00584			ko00000,ko00001,ko00002,ko02000	3.A.1			Bacteria	COG0577@1,COG0577@2	NA|NA|NA	V	efflux transmembrane transporter activity
AHPHCOMF_01579	264199.stu0536	1.6e-77	295.4	Bacilli	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113		ko:K02864,ko:K02935	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V3JJ@1239,4HH0N@91061,COG0244@1,COG0244@2	NA|NA|NA	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AHPHCOMF_01580	264199.stu0537	3.9e-52	210.7	Bacilli	rplL			ko:K02935	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V6EI@1239,4HIGQ@91061,COG0222@1,COG0222@2	NA|NA|NA	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
AHPHCOMF_01581	1116231.SMA_0720	8e-216	756.1	Bacilli													Bacteria	1TQ93@1239,4HJK9@91061,COG3464@1,COG3464@2	NA|NA|NA	L	Transposase
AHPHCOMF_01582	1410626.JHXB01000031_gene1709	1.6e-18	98.2	unclassified Lachnospiraceae													Bacteria	1TRUP@1239,24AJD@186801,27KEC@186928,COG2801@1,COG2801@2	NA|NA|NA	L	Integrase core domain
AHPHCOMF_01583	322159.STER_1348	1.3e-117	429.1	Bacilli	devA		3.6.3.25	ko:K02003,ko:K06020,ko:K09810	ko02010,map02010	M00255,M00258			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125			Bacteria	1TQP5@1239,4HBXK@91061,COG1136@1,COG1136@2	NA|NA|NA	V	abc transporter atp-binding protein
AHPHCOMF_01584	322159.STER_1347	2.8e-164	584.7	Bacilli	hrtB			ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	1VRMK@1239,4HTA7@91061,COG0577@1,COG0577@2	NA|NA|NA	V	MacB-like periplasmic core domain
AHPHCOMF_01587	322159.STER_0574	3e-92	345.1	Bacteria													Bacteria	2DVN5@1,33WG3@2	NA|NA|NA	S	MucBP domain
AHPHCOMF_01588	904306.HMPREF9192_0446	1.9e-49	201.8	Bacilli				ko:K14194,ko:K14195	ko05150,map05150				ko00000,ko00001				Bacteria	1UYRE@1239,4ISZF@91061,COG2373@1,COG2373@2,COG4932@1,COG4932@2	NA|NA|NA	M	YSIRK type signal peptide
AHPHCOMF_01589	322159.STER_0576	0.0	1187.2	Firmicutes													Bacteria	1V15F@1239,COG3266@1,COG3266@2	NA|NA|NA	M	the current gene model (or a revised gene model) may contain a
AHPHCOMF_01591	322159.STER_0578	0.0	1098.6	Bacilli	mdlB			ko:K06147,ko:K06148,ko:K18887	ko02010,map02010	M00706			ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21			Bacteria	1TP0B@1239,4H9SC@91061,COG1132@1,COG1132@2	NA|NA|NA	V	abc transporter atp-binding protein
AHPHCOMF_01592	322159.STER_0579	0.0	1138.3	Bacilli	lmrA			ko:K06147,ko:K18888	ko02010,map02010	M00706			ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21			Bacteria	1TP0B@1239,4HA3S@91061,COG1132@1,COG1132@2	NA|NA|NA	V	abc transporter atp-binding protein
AHPHCOMF_01593	322159.STER_0580	4.6e-199	700.3	Bacilli	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568					ko00000,ko01000,ko03016				Bacteria	1TPKD@1239,4H9PT@91061,COG0809@1,COG0809@2	NA|NA|NA	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AHPHCOMF_01594	1046629.Ssal_01624	3.4e-121	441.0	Bacilli	nagB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0008150,GO:0008152,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135	3.1.1.31,3.5.99.6	ko:K01057,ko:K02564	ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R00765,R02035	RC00163,RC00537	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP10@1239,4HAG4@91061,COG0363@1,COG0363@2	NA|NA|NA	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
AHPHCOMF_01595	322159.STER_0582	1.3e-214	752.3	Bacilli			2.7.13.3	ko:K07706	ko02020,ko02024,map02020,map02024	M00495			ko00000,ko00001,ko00002,ko01000,ko01001,ko02022				Bacteria	1UDI2@1239,4HF65@91061,COG3290@1,COG3290@2	NA|NA|NA	T	signal transduction protein with a C-terminal ATPase domain
AHPHCOMF_01596	322159.STER_0583	2.1e-131	474.9	Bacilli	rr02												Bacteria	1TXDF@1239,4HDA7@91061,COG3279@1,COG3279@2	NA|NA|NA	KT	response regulator
AHPHCOMF_01597	264199.stu0545	1.1e-217	762.3	Bacilli			2.7.7.73,2.7.7.80	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122		R07459	RC00043	ko00000,ko00001,ko01000				Bacteria	1TQ3U@1239,4HBGP@91061,COG0476@1,COG0476@2	NA|NA|NA	H	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
AHPHCOMF_01598	322159.STER_0586	4.8e-168	597.0	Bacilli				ko:K01990,ko:K01992		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1UZK5@1239,4HB2Q@91061,COG1131@1,COG1131@2	NA|NA|NA	V	ABC transporter
AHPHCOMF_01599	264199.stu0547	5.4e-122	443.7	Bacilli	sagI			ko:K01992		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1USMY@1239,4HC3J@91061,COG1511@1,COG1511@2	NA|NA|NA	S	ABC-2 type transporter
AHPHCOMF_01600	264199.stu0548	1e-195	689.1	Bacilli	yceA			ko:K07146					ko00000				Bacteria	1TRG7@1239,4HA0J@91061,COG1054@1,COG1054@2	NA|NA|NA	S	Belongs to the UPF0176 family
AHPHCOMF_01601	655813.HMPREF8579_1629	3.3e-22	111.7	Streptococcus oralis													Bacteria	1TWW2@1239,1WPHP@1303,29QF9@1,30BEN@2,4I5QM@91061	NA|NA|NA		
AHPHCOMF_01602	322159.STER_0591	1.5e-143	515.4	Bacilli	deoD_1		2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100		R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000				Bacteria	1V6T2@1239,4HCSE@91061,COG2820@1,COG2820@2	NA|NA|NA	F	Phosphorylase superfamily
AHPHCOMF_01603	322159.STER_0592	5.6e-113	413.7	Bacilli													Bacteria	1V6KW@1239,4IPIC@91061,COG1814@1,COG1814@2	NA|NA|NA	S	VIT family
AHPHCOMF_01604	264199.stu0553	7.4e-132	476.5	Bacilli	rsuA		5.4.99.19,5.4.99.22	ko:K06178,ko:K06183					ko00000,ko01000,ko03009				Bacteria	1TQZ2@1239,4H9VU@91061,COG1187@1,COG1187@2	NA|NA|NA	J	Belongs to the pseudouridine synthase RsuA family
AHPHCOMF_01605	322159.STER_0594	8e-221	772.7	Bacilli	hipO		3.5.1.47	ko:K01436,ko:K05823,ko:K21613	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00525	R02733	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000,ko01002				Bacteria	1TPD7@1239,4H9WQ@91061,COG1473@1,COG1473@2	NA|NA|NA	E	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
AHPHCOMF_01606	264199.stu0555	3.4e-17	93.2	Bacteria	ald	GO:0000286,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009653,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030154,GO:0030435,GO:0032502,GO:0043436,GO:0043934,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048646,GO:0048856,GO:0048869,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100		R00396	RC00008	ko00000,ko00001,ko01000			iAF987.Gmet_1099	Bacteria	COG0686@1,COG0686@2	NA|NA|NA	E	alanine dehydrogenase activity
AHPHCOMF_01607	435842.HMPREF0848_00185	2.2e-46	191.4	Bacilli	ald	GO:0000286,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009653,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030154,GO:0030435,GO:0032502,GO:0043436,GO:0043934,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048646,GO:0048856,GO:0048869,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100		R00396	RC00008	ko00000,ko00001,ko01000			iAF987.Gmet_1099	Bacteria	1TNZ5@1239,4HABX@91061,COG0686@1,COG0686@2	NA|NA|NA	C	Belongs to the AlaDH PNT family
AHPHCOMF_01608	264199.stu0557	8e-249	865.9	Bacilli	merA	GO:0000302,GO:0000305,GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0019725,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901530,GO:1901700,GO:1990748	1.16.1.1	ko:K00520,ko:K21739					ko00000,ko01000				Bacteria	1TP1W@1239,4HBZF@91061,COG1249@1,COG1249@2	NA|NA|NA	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AHPHCOMF_01609	264199.stu0558	1.4e-104	385.6	Bacilli	GBS0088			ko:K09962					ko00000				Bacteria	1V1YD@1239,4HGK6@91061,COG3575@1,COG3575@2	NA|NA|NA	J	protein conserved in bacteria
AHPHCOMF_01610	264199.stu0559	2.5e-142	511.5	Bacilli	mvk		1.1.1.88,2.3.3.10,2.7.1.36	ko:K00054,ko:K00869,ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,ko04146,map00072,map00280,map00650,map00900,map01100,map01110,map01130,map04146	M00088,M00095	R01978,R02081,R02245	RC00002,RC00004,RC00017,RC00503,RC00644	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPVW@1239,4IRCB@91061,COG1577@1,COG1577@2	NA|NA|NA	I	mevalonate kinase
AHPHCOMF_01611	264199.stu0560	6e-174	616.7	Bacilli	mvaD		4.1.1.33	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095	R01121	RC00453	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQXR@1239,4HAM6@91061,COG3407@1,COG3407@2	NA|NA|NA	I	diphosphomevalonate decarboxylase
AHPHCOMF_01612	322159.STER_0600	4.6e-180	637.1	Bacilli	mvaK2		2.7.1.36,2.7.1.43,2.7.4.2	ko:K00869,ko:K00938,ko:K16190	ko00040,ko00053,ko00520,ko00900,ko01100,ko01110,ko01130,ko04146,map00040,map00053,map00520,map00900,map01100,map01110,map01130,map04146	M00014,M00095	R01476,R02245,R03245	RC00002,RC00017,RC00078	ko00000,ko00001,ko00002,ko01000				Bacteria	1VXNZ@1239,4IRFS@91061,COG1577@1,COG1577@2	NA|NA|NA	I	GHMP kinases N terminal domain
AHPHCOMF_01613	322159.STER_0601	8.9e-192	676.0	Bacilli	fni		1.1.1.88,5.3.3.2	ko:K00054,ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123,R02081	RC00004,RC00455,RC00644	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQZ3@1239,4HAMV@91061,COG1304@1,COG1304@2	NA|NA|NA	C	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
AHPHCOMF_01614	322159.STER_0603	5.1e-254	883.2	Bacilli	glmU	GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030203,GO:0030260,GO:0033692,GO:0034637,GO:0034645,GO:0035635,GO:0040007,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509	2.3.1.157,2.7.7.23	ko:K04042,ko:K11528	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP88@1239,4H9V5@91061,COG1207@1,COG1207@2	NA|NA|NA	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AHPHCOMF_01615	322159.STER_0604	8.5e-96	356.3	Bacilli	nudF		3.6.1.13	ko:K01515	ko00230,map00230		R01054	RC00002	ko00000,ko00001,ko01000			iHN637.CLJU_RS05505,iSB619.SA_RS07540,iYO844.BSU23610	Bacteria	1V6F5@1239,4HII9@91061,COG0494@1,COG0494@2	NA|NA|NA	L	AdP-ribose pyrophosphatase
AHPHCOMF_01616	322159.STER_0605	2.5e-21	107.8	Bacteria													Bacteria	2DC3Q@1,2ZCSA@2	NA|NA|NA		
AHPHCOMF_01617	264199.stu0566	5.9e-118	430.3	Bacilli	mtnN		3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000				Bacteria	1U7WK@1239,4HB8K@91061,COG0775@1,COG0775@2	NA|NA|NA	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AHPHCOMF_01619	1046629.Ssal_01596	3.5e-07	60.1	Bacteria				ko:K02460	ko03070,ko05111,map03070,map05111	M00331			ko00000,ko00001,ko00002,ko02044	3.A.15			Bacteria	COG3156@1,COG3156@2,COG4932@1,COG4932@2	NA|NA|NA	U	protein secretion
AHPHCOMF_01620	1046629.Ssal_01596	2.7e-50	204.9	Bacteria				ko:K02460	ko03070,ko05111,map03070,map05111	M00331			ko00000,ko00001,ko00002,ko02044	3.A.15			Bacteria	COG3156@1,COG3156@2,COG4932@1,COG4932@2	NA|NA|NA	U	protein secretion
AHPHCOMF_01621	1046629.Ssal_01596	1.1e-11	76.6	Bacteria				ko:K02460	ko03070,ko05111,map03070,map05111	M00331			ko00000,ko00001,ko00002,ko02044	3.A.15			Bacteria	COG3156@1,COG3156@2,COG4932@1,COG4932@2	NA|NA|NA	U	protein secretion
AHPHCOMF_01622	264199.stu0569	1.4e-192	678.7	Bacilli	dgs		2.4.1.208	ko:K13677	ko00561,ko01100,map00561,map01100		R05164	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003		GT4		Bacteria	1TPSS@1239,4HBKA@91061,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyltransferase, group 1 family protein
AHPHCOMF_01623	264199.stu0570	1.8e-248	864.8	Bacilli	mgs	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576	2.4.1.337	ko:K19002	ko00561,ko01100,map00561,map01100		R10850	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003		GT4		Bacteria	1TPTA@1239,4HA41@91061,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyltransferase, group 1 family protein
AHPHCOMF_01624	904306.HMPREF9192_1298	4.9e-21	106.7	Bacilli	XK27_13030												Bacteria	1VBNS@1239,2DMJF@1,32RYX@2,4HMXU@91061	NA|NA|NA		
AHPHCOMF_01625	264199.stu0572	0.0	1319.7	Bacilli	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1TP78@1239,4HABZ@91061,COG0441@1,COG0441@2	NA|NA|NA	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AHPHCOMF_01626	264199.stu0573	9.9e-169	599.4	Bacilli													Bacteria	1V202@1239,4HJ0U@91061,COG0596@1,COG0596@2	NA|NA|NA	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
AHPHCOMF_01627	264199.stu0574	9.8e-163	579.3	Bacilli													Bacteria	1VFZ3@1239,2DQ82@1,3357U@2,4HNXV@91061	NA|NA|NA	S	Protein of unknown function (DUF3114)
AHPHCOMF_01628	904306.HMPREF9192_1302	1.2e-22	111.7	Bacilli													Bacteria	1VFZ3@1239,2DQ82@1,3357U@2,4HNXV@91061	NA|NA|NA	S	Protein of unknown function (DUF3114)
AHPHCOMF_01629	264199.stu0575	1.1e-116	426.0	Bacilli	yqfA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K11068					ko00000,ko02042				Bacteria	1TTA5@1239,4HDYT@91061,COG1272@1,COG1272@2	NA|NA|NA	K	protein, Hemolysin III
AHPHCOMF_01630	322159.STER_0620	2.7e-233	814.3	Bacilli	mvaA		1.1.1.34,1.1.1.88,2.3.1.9	ko:K00021,ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,ko04152,ko04976,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020,map04152,map04976	M00088,M00095,M00373,M00374,M00375	R00238,R01177,R02081,R02082	RC00004,RC00326,RC00644	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1TPNY@1239,4HBQ3@91061,COG1257@1,COG1257@2	NA|NA|NA	C	Belongs to the HMG-CoA reductase family
AHPHCOMF_01631	264199.stu0577	1.7e-218	765.0	Bacilli	mvaS		2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000				Bacteria	1TR4K@1239,4HA67@91061,COG3425@1,COG3425@2	NA|NA|NA	I	synthase
AHPHCOMF_01632	322159.STER_0622	2.2e-167	594.7	Bacilli	thyA		2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000				Bacteria	1TSIR@1239,4HI1C@91061,COG0207@1,COG0207@2	NA|NA|NA	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AHPHCOMF_01633	264199.stu0579	3.4e-91	340.9	Bacilli	folA		1.5.1.3,1.5.1.47,2.1.1.45,3.5.4.12	ko:K00287,ko:K00560,ko:K01493,ko:K05896,ko:K17364	ko00240,ko00670,ko00790,ko01100,ko01523,map00240,map00670,map00790,map01100,map01523	M00053,M00126,M00429,M00840	R00936,R00937,R00939,R00940,R01663,R02101,R02235,R02236,R03388,R11765	RC00074,RC00109,RC00110,RC00158,RC00219,RC00332,RC01584	ko00000,ko00001,ko00002,ko01000,ko02044,ko03036				Bacteria	1VB80@1239,4HIGJ@91061,COG0262@1,COG0262@2	NA|NA|NA	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AHPHCOMF_01634	435842.HMPREF0848_00215	9.7e-22	108.6	Bacilli													Bacteria	1W5G0@1239,2DFKW@1,2ZS8U@2,4HZFD@91061	NA|NA|NA		
AHPHCOMF_01635	264199.stu0581	2e-225	788.1	Bacilli	clpX	GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369		ko:K03544	ko04112,map04112				ko00000,ko00001,ko03110				Bacteria	1TQ00@1239,4H9U4@91061,COG1219@1,COG1219@2	NA|NA|NA	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AHPHCOMF_01636	322159.STER_0626	4.3e-109	400.6	Bacilli	engB	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363		ko:K03978					ko00000,ko03036				Bacteria	1TSPW@1239,4HBXZ@91061,COG0218@1,COG0218@2	NA|NA|NA	D	Necessary for normal cell division and for the maintenance of normal septation
AHPHCOMF_01637	264199.stu0583	4.1e-248	863.6	Bacilli	mmuP	GO:0000096,GO:0000097,GO:0000100,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0015806,GO:0016020,GO:0016053,GO:0019752,GO:0022857,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682		ko:K02205,ko:K03293,ko:K16235,ko:K16236					ko00000,ko02000	2.A.3.1,2.A.3.1.10			Bacteria	1UHNR@1239,4HUT7@91061,COG0833@1,COG0833@2	NA|NA|NA	E	amino acid
AHPHCOMF_01638	322159.STER_0628	1.2e-177	629.0	Bacilli	mmuM	GO:0003674,GO:0003824,GO:0005488,GO:0006575,GO:0006790,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008270,GO:0008757,GO:0008898,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033477,GO:0033554,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:1901564	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000				Bacteria	1UHQ5@1239,4HAS6@91061,COG2040@1,COG2040@2	NA|NA|NA	H	Homocysteine
AHPHCOMF_01639	1035184.HMPREF1042_0385	1.4e-29	135.2	Streptococcus anginosus group													Bacteria	1VYRT@1239,2BXCI@1,346RD@2,42DR8@671232,4HYPP@91061	NA|NA|NA	S	Domain of unknown function (DUF1912)
AHPHCOMF_01640	759913.SDSE_1678	4.9e-15	87.4	Streptococcus dysgalactiae group													Bacteria	1M9TG@119603,1TXCP@1239,2DJ7H@1,304X7@2,4I6AH@91061	NA|NA|NA	L	Helix-hairpin-helix DNA-binding motif class 1
AHPHCOMF_01641	264199.stu0587	7.1e-102	376.7	Bacilli	plsY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.3.1.15,3.5.1.104	ko:K08591,ko:K22278	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	1VA3J@1239,4HC55@91061,COG0344@1,COG0344@2	NA|NA|NA	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
AHPHCOMF_01642	264199.stu0588	0.0	1226.5	Bacilli	parE	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034335,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.3	ko:K02470,ko:K02622					ko00000,ko01000,ko02048,ko03032,ko03036,ko03400				Bacteria	1TQCF@1239,4H9UC@91061,COG0187@1,COG0187@2	NA|NA|NA	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AHPHCOMF_01643	264199.stu0589	0.0	1565.4	Bacilli	parC	GO:0005575,GO:0005622,GO:0005623,GO:0009330,GO:0032991,GO:0044424,GO:0044464	5.99.1.3	ko:K02469,ko:K02621					ko00000,ko01000,ko02048,ko03032,ko03036,ko03400				Bacteria	1TRE7@1239,4HAQB@91061,COG0188@1,COG0188@2	NA|NA|NA	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AHPHCOMF_01644	264199.stu0590	2.4e-200	704.5	Bacilli	ilvE		2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	1TQQI@1239,4HASX@91061,COG0115@1,COG0115@2	NA|NA|NA	E	Aminotransferase
AHPHCOMF_01645	1035187.HMPREF9959_0525	4.8e-16	90.1	Streptococcus mitis													Bacteria	1U4J6@1239,29N96@1,2TPZ6@28037,30971@2,4IEAX@91061	NA|NA|NA	S	Protein of unknown function (DUF2969)
AHPHCOMF_01648	264199.stu0592	8.4e-205	719.5	Bacilli	rpsA		1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011				Bacteria	1TQ9N@1239,4H9PX@91061,COG0539@1,COG0539@2	NA|NA|NA	J	ribosomal protein S1
AHPHCOMF_01651	904306.HMPREF9192_1327	2.6e-101	374.8	Bacilli													Bacteria	1VGN9@1239,2DMIQ@1,32RV1@2,4I0DZ@91061	NA|NA|NA	S	Domain of Unknown Function with PDB structure (DUF3862)
AHPHCOMF_01652	1046629.Ssal_01562	6.1e-70	270.4	Bacteria													Bacteria	COG0398@1,COG0398@2	NA|NA|NA	M	Pfam SNARE associated Golgi protein
AHPHCOMF_01653	264199.stu0596	1.3e-232	812.0	Bacilli	murN		2.3.2.10,2.3.2.16	ko:K05363,ko:K11693,ko:K12554	ko00550,ko01100,map00550,map01100		R08776,R08779,R08780	RC00055,RC00064,RC00096	ko00000,ko00001,ko01000,ko01011				Bacteria	1V181@1239,4HEVU@91061,COG2348@1,COG2348@2	NA|NA|NA	V	FemAB family
AHPHCOMF_01654	904306.HMPREF9192_1330	9.3e-59	232.6	Bacilli				ko:K22230	ko00562,ko01120,map00562,map01120		R09954	RC00182	ko00000,ko00001,ko01000				Bacteria	1TQSS@1239,4HDXF@91061,COG0673@1,COG0673@2	NA|NA|NA	S	oxidoreductase
AHPHCOMF_01655	904306.HMPREF9192_1330	9.7e-66	256.1	Bacilli				ko:K22230	ko00562,ko01120,map00562,map01120		R09954	RC00182	ko00000,ko00001,ko01000				Bacteria	1TQSS@1239,4HDXF@91061,COG0673@1,COG0673@2	NA|NA|NA	S	oxidoreductase
AHPHCOMF_01656	264199.stu0600	3.7e-48	197.2	Bacilli	XK27_09445												Bacteria	1VFRS@1239,2EBZ8@1,335YI@2,4HNUK@91061	NA|NA|NA	S	Domain of unknown function (DUF1827)
AHPHCOMF_01657	264199.stu0601	6.7e-86	323.2	Bacilli	mutT		3.5.4.33,3.6.1.13,3.6.1.55	ko:K01515,ko:K03574,ko:K11991	ko00230,map00230		R01054,R10223	RC00002,RC00477	ko00000,ko00001,ko01000,ko03016,ko03400				Bacteria	1VH6Q@1239,4HQVJ@91061,COG0494@1,COG0494@2	NA|NA|NA	L	Belongs to the Nudix hydrolase family
AHPHCOMF_01658	264199.stu0602	0.0	1316.2	Bacilli	clpE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K03697					ko00000,ko03110				Bacteria	1TPMU@1239,4HA0V@91061,COG0542@1,COG0542@2	NA|NA|NA	O	Belongs to the ClpA ClpB family
AHPHCOMF_01659	264199.stu0603	2.6e-180	637.9	Bacilli	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPF2@1239,4H9X8@91061,COG0078@1,COG0078@2	NA|NA|NA	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AHPHCOMF_01660	264199.stu0604	1.3e-34	151.8	Bacilli	ykuJ												Bacteria	1VKD0@1239,4HRGC@91061,COG4703@1,COG4703@2	NA|NA|NA	S	protein conserved in bacteria
AHPHCOMF_01661	264199.stu0605	7.5e-118	429.9	Bacilli	WQ51_01820			ko:K02029,ko:K02030,ko:K10040,ko:K17073,ko:K17074	ko02010,map02010	M00228,M00236,M00589			ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.20			Bacteria	1TPM3@1239,4IQKK@91061,COG0765@1,COG0765@2	NA|NA|NA	P	Binding-protein-dependent transport system inner membrane component
AHPHCOMF_01662	264199.stu0606	2.2e-131	474.9	Bacilli	glnQ		3.6.3.21	ko:K02028		M00236			ko00000,ko00002,ko01000,ko02000	3.A.1.3			Bacteria	1TNYD@1239,4H9WY@91061,COG1126@1,COG1126@2	NA|NA|NA	E	abc transporter atp-binding protein
AHPHCOMF_01663	264199.stu0607	3.1e-78	297.7	Bacilli	feoA			ko:K04758					ko00000,ko02000				Bacteria	1VEHC@1239,4HPFS@91061,COG1918@1,COG1918@2	NA|NA|NA	P	FeoA domain protein
AHPHCOMF_01664	264199.stu0608	0.0	1369.0	Bacilli	feoB			ko:K04759					ko00000,ko02000	9.A.8.1			Bacteria	1TP7E@1239,4HBCS@91061,COG0370@1,COG0370@2	NA|NA|NA	P	transporter of a GTP-driven Fe(2 ) uptake system
AHPHCOMF_01665	663952.SDD27957_07575	1.5e-07	61.2	Streptococcus dysgalactiae group													Bacteria	1MA5P@119603,1TXF8@1239,2DJ8A@1,304YV@2,4I6DK@91061	NA|NA|NA		
AHPHCOMF_01666	322159.STER_0656	2.4e-104	384.8	Bacilli			1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000				Bacteria	1TRVB@1239,4HFQB@91061,COG1898@1,COG1898@2	NA|NA|NA	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
AHPHCOMF_01667	322159.STER_0657	2.2e-45	188.0	Bacteria				ko:K20374	ko02024,map02024				ko00000,ko00001,ko03000				Bacteria	COG1396@1,COG1396@2	NA|NA|NA	K	sequence-specific DNA binding
AHPHCOMF_01668	264199.stu0609	1.5e-35	154.8	Bacteria	yugF	GO:0003674,GO:0003824,GO:0016787											Bacteria	COG2267@1,COG2267@2	NA|NA|NA	I	carboxylic ester hydrolase activity
AHPHCOMF_01669	1046629.Ssal_01547	7.5e-23	112.5	Bacilli													Bacteria	1V37Y@1239,4ITDD@91061,COG2267@1,COG2267@2	NA|NA|NA	I	Alpha/beta hydrolase family
AHPHCOMF_01670	322159.STER_0660	3.9e-156	557.4	Bacilli	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP1P@1239,4H9Q6@91061,COG0190@1,COG0190@2	NA|NA|NA	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AHPHCOMF_01671	264199.stu0612	7.8e-149	533.1	Bacilli	nnrD		4.2.1.136,5.1.99.6	ko:K17758,ko:K17759					ko00000,ko01000				Bacteria	1TNZE@1239,4HBZC@91061,COG0063@1,COG0063@2	NA|NA|NA	H	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AHPHCOMF_01672	322159.STER_0662	0.0	1253.0	Bacilli	pbp2b		3.4.16.4	ko:K00687,ko:K05515,ko:K12553,ko:K21465	ko00550,ko01100,ko01501,map00550,map01100,map01501				ko00000,ko00001,ko01000,ko01011				Bacteria	1TQHY@1239,4HAFX@91061,COG0768@1,COG0768@2	NA|NA|NA	M	penicillin-binding protein
AHPHCOMF_01673	322159.STER_0663	2.2e-105	388.3	Bacilli	recR	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576		ko:K06187	ko03440,map03440				ko00000,ko00001,ko03400				Bacteria	1TR87@1239,4HAZR@91061,COG0353@1,COG0353@2	NA|NA|NA	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AHPHCOMF_01675	264199.stu0615	9.2e-43	179.1	Bacteria	licT			ko:K02538,ko:K03488					ko00000,ko03000				Bacteria	COG3711@1,COG3711@2	NA|NA|NA	K	transcriptional antiterminator
AHPHCOMF_01676	264199.stu0616	6.8e-53	213.0	Bacteria	licT			ko:K02538,ko:K03488					ko00000,ko03000				Bacteria	COG3711@1,COG3711@2	NA|NA|NA	K	transcriptional antiterminator
AHPHCOMF_01677	264199.stu0617	1.1e-86	325.9	Bacilli	ybeY	GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141	2.6.99.2,3.5.4.5	ko:K01489,ko:K03474,ko:K03595,ko:K07042	ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100	M00124	R01878,R02485,R05838,R08221	RC00074,RC00514,RC01476	ko00000,ko00001,ko00002,ko01000,ko03009,ko03029				Bacteria	1V6BU@1239,4HIIE@91061,COG0319@1,COG0319@2	NA|NA|NA	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AHPHCOMF_01678	264199.stu0618	1.7e-64	251.9	Bacilli	dgkA		2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231		R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000			iAF987.Gmet_2369,iSB619.SA_RS07900	Bacteria	1VEGR@1239,4HNKN@91061,COG0818@1,COG0818@2	NA|NA|NA	M	Diacylglycerol kinase
AHPHCOMF_01679	264199.stu0619	1.3e-165	589.0	Bacilli	era	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113		ko:K03595,ko:K06883					ko00000,ko03009,ko03029				Bacteria	1TP3R@1239,4H9WF@91061,COG1159@1,COG1159@2	NA|NA|NA	M	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AHPHCOMF_01680	264199.stu0620	1.2e-154	552.4	Bacilli	fpg		3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	1TPM9@1239,4H9Q7@91061,COG0266@1,COG0266@2	NA|NA|NA	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
AHPHCOMF_01681	264199.stu0621	1.1e-104	386.0	Bacilli	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24,3.2.2.23,4.2.99.18	ko:K00859,ko:K08309,ko:K10563	ko00770,ko01100,ko03410,map00770,map01100,map03410	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01011,ko03400		GH23	iIT341.HP0831	Bacteria	1V6FS@1239,4HII3@91061,COG0237@1,COG0237@2	NA|NA|NA	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AHPHCOMF_01682	264199.stu0622	6e-133	480.3	Bacilli	mdtG	GO:0006810,GO:0006855,GO:0008150,GO:0015893,GO:0042221,GO:0042493,GO:0050896,GO:0051179,GO:0051234,GO:0055085		ko:K08161					ko00000,ko02000	2.A.1.2.20			Bacteria	1TRDJ@1239,4H9Q9@91061,COG0477@1,COG2814@2	NA|NA|NA	EGP	Major facilitator Superfamily
AHPHCOMF_01683	264199.stu0622	9.5e-74	282.7	Bacilli	mdtG	GO:0006810,GO:0006855,GO:0008150,GO:0015893,GO:0042221,GO:0042493,GO:0050896,GO:0051179,GO:0051234,GO:0055085		ko:K08161					ko00000,ko02000	2.A.1.2.20			Bacteria	1TRDJ@1239,4H9Q9@91061,COG0477@1,COG2814@2	NA|NA|NA	EGP	Major facilitator Superfamily
AHPHCOMF_01684	264199.stu0624	2e-33	147.9	Bacilli	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680		ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2			Bacteria	1VEQR@1239,4HNKC@91061,COG1314@1,COG1314@2	NA|NA|NA	U	Preprotein translocase subunit SecG
AHPHCOMF_01685	264199.stu0625	0.0	1506.5	Bacilli	rnr			ko:K12573,ko:K12585	ko03018,map03018	M00391			ko00000,ko00001,ko00002,ko01000,ko03016,ko03019				Bacteria	1TQ1G@1239,4HBBH@91061,COG0557@1,COG0557@2	NA|NA|NA	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
AHPHCOMF_01686	264199.stu0626	1.1e-80	305.8	Bacilli	smpB	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564		ko:K03664					ko00000				Bacteria	1V3IJ@1239,4HGZX@91061,COG0691@1,COG0691@2	NA|NA|NA	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
AHPHCOMF_01687	322159.STER_0676	9.6e-277	958.7	Bacilli	ppiB	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217				ko00000,ko00001,ko01000,ko03110,ko04147				Bacteria	1TRHW@1239,4H9V0@91061,COG0561@1,COG0561@2,COG0652@1,COG0652@2	NA|NA|NA	G	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AHPHCOMF_01688	264199.stu0628	1.7e-63	248.4	Bacilli	yugI		5.3.1.9	ko:K01810,ko:K02945,ko:K07570,ko:K07571,ko:K19142	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko03010,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map03010	M00001,M00004,M00114,M00178	R02739,R02740,R03321	RC00376,RC00563	br01610,ko00000,ko00001,ko00002,ko01000,ko02048,ko03011,ko04147				Bacteria	1VASQ@1239,4HKSW@91061,COG1098@1,COG1098@2	NA|NA|NA	J	RNA binding protein, contains ribosomal protein S1 domain
AHPHCOMF_01689	322159.STER_0678	4.2e-211	740.3	Bacilli	pepQ		3.4.13.9	ko:K01271					ko00000,ko01000,ko01002				Bacteria	1TQ6R@1239,4HA5I@91061,COG0006@1,COG0006@2	NA|NA|NA	E	Belongs to the peptidase M24B family
AHPHCOMF_01690	322159.STER_0679	4.4e-183	647.1	Bacilli	ccpA	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141		ko:K02529					ko00000,ko03000				Bacteria	1TQ7K@1239,4H9NG@91061,COG1609@1,COG1609@2	NA|NA|NA	K	Catabolite control protein A
AHPHCOMF_01691	904306.HMPREF9192_1362	2.8e-28	130.6	Bacilli	yyaQ												Bacteria	1V4K7@1239,4HP2K@91061,COG2315@1,COG2315@2	NA|NA|NA	S	YjbR
AHPHCOMF_01692	322159.STER_0681	6.6e-101	373.2	Bacteria	yyaQ												Bacteria	COG2315@1,COG2315@2	NA|NA|NA	V	Protein conserved in bacteria
AHPHCOMF_01693	322159.STER_0682	1.3e-207	728.8	Firmicutes	glxK		2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130		R08572	RC00002,RC00428	ko00000,ko00001,ko01000				Bacteria	1TPSI@1239,COG1929@1,COG1929@2	NA|NA|NA	G	Belongs to the glycerate kinase type-1 family
AHPHCOMF_01694	322159.STER_0683	1e-78	299.3	Bacilli	yueI												Bacteria	1VFCV@1239,4HNNE@91061,COG5506@1,COG5506@2	NA|NA|NA	S	Protein of unknown function (DUF1694)
AHPHCOMF_01695	322159.STER_0684	9.6e-247	859.0	Bacilli	eno	GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0009986,GO:0016829,GO:0016835,GO:0016836,GO:0019899,GO:0030312,GO:0035375,GO:0043236,GO:0044424,GO:0044464,GO:0044877,GO:0050840,GO:0071944	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147				Bacteria	1TP2S@1239,4HAKI@91061,COG0148@1,COG0148@2	NA|NA|NA	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
AHPHCOMF_01696	322159.STER_0685	2e-25	120.9	Firmicutes	WQ51_00785												Bacteria	1W67C@1239,2FKS5@1,34CCP@2	NA|NA|NA		
AHPHCOMF_01697	264199.stu0636	0.0	1399.0	Bacilli	ltaS	GO:0005575,GO:0005576	2.7.8.20	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100		R05081,R10849	RC00017	ko00000,ko00001,ko01000				Bacteria	1TRMA@1239,4H9S0@91061,COG1368@1,COG1368@2	NA|NA|NA	M	Belongs to the LTA synthase family
AHPHCOMF_01698	264199.stu0637	9.9e-219	765.8	Bacilli	ywbD		2.1.1.191	ko:K06969					ko00000,ko01000,ko03009				Bacteria	1TRAJ@1239,4HAA1@91061,COG1092@1,COG1092@2	NA|NA|NA	J	Methyltransferase
AHPHCOMF_01699	322159.STER_0688	8.6e-122	443.0	Bacilli	aroD	GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25,4.2.1.10	ko:K03785,ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413,R03084	RC00206,RC00848	ko00000,ko00001,ko00002,ko01000				Bacteria	1VHVX@1239,4IPJP@91061,COG0710@1,COG0710@2	NA|NA|NA	E	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
AHPHCOMF_01700	322159.STER_0689	1.7e-162	578.6	Bacilli	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQRY@1239,4HD4R@91061,COG0169@1,COG0169@2	NA|NA|NA	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AHPHCOMF_01701	322159.STER_0690	3.5e-202	710.7	Bacilli	aroB		2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPKZ@1239,4HAKN@91061,COG0337@1,COG0337@2	NA|NA|NA	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AHPHCOMF_01702	264199.stu0641	4.5e-219	766.9	Bacilli	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_0976,iNJ661.Rv2540c	Bacteria	1TQ40@1239,4HA0H@91061,COG0082@1,COG0082@2	NA|NA|NA	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AHPHCOMF_01703	322159.STER_0692	2.2e-207	728.0	Bacilli	tyrA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.3.1.12,1.3.1.43	ko:K00210,ko:K00220,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025,M00040	R00732,R01728	RC00125	ko00000,ko00001,ko00002,ko01000			iYO844.BSU22610	Bacteria	1TPXG@1239,4HBI4@91061,COG0287@1,COG0287@2	NA|NA|NA	E	prephenate dehydrogenase
AHPHCOMF_01704	264199.stu0643	3.2e-53	214.2	Bacilli	yheA												Bacteria	1VASS@1239,4HPJM@91061,COG3679@1,COG3679@2	NA|NA|NA	S	Belongs to the UPF0342 family
AHPHCOMF_01705	322159.STER_0694	3e-173	614.4	Bacilli	ldh		1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922		R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147				Bacteria	1UXY2@1239,4HD1S@91061,COG0039@1,COG0039@2	NA|NA|NA	C	Belongs to the LDH MDH superfamily
AHPHCOMF_01706	322159.STER_0695	7.5e-236	822.8	Bacilli	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	1.3.1.12,1.3.1.43,2.5.1.19	ko:K00210,ko:K00220,ko:K00800	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00022,M00025,M00040	R00732,R01728,R03460	RC00125,RC00350	ko00000,ko00001,ko00002,ko01000			iLJ478.TM0345	Bacteria	1TPIH@1239,4HBHZ@91061,COG0128@1,COG0128@2	NA|NA|NA	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
AHPHCOMF_01707	322159.STER_0696	1.7e-87	328.6	Bacilli	aroK	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019438,GO:0019632,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615	1.1.1.25,2.7.1.71,4.2.1.10,4.2.3.4	ko:K00014,ko:K00891,ko:K03785,ko:K03786,ko:K13829,ko:K15546	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R02413,R03083,R03084	RC00002,RC00078,RC00206,RC00847,RC00848	ko00000,ko00001,ko00002,ko01000,ko03000			iAPECO1_1312.APECO1_1620,iECOK1_1307.ECOK1_0367,iECS88_1305.ECS88_0383,iUMN146_1321.UM146_15425,iUTI89_1310.UTI89_C0407,iYL1228.KPN_00332	Bacteria	1VA6Z@1239,4HKD6@91061,COG0703@1,COG0703@2	NA|NA|NA	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AHPHCOMF_01708	264199.stu0647	2.3e-153	548.1	Bacilli	pheA	GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000			iYO844.BSU27900	Bacteria	1TPDN@1239,4HA96@91061,COG0077@1,COG0077@2	NA|NA|NA	E	Prephenate dehydratase
AHPHCOMF_01709	322159.STER_0698	2.6e-253	880.9	Bacilli	msrR												Bacteria	1TSWQ@1239,4HE66@91061,COG1316@1,COG1316@2	NA|NA|NA	K	Transcriptional regulator
AHPHCOMF_01710	322159.STER_0699	2.2e-149	535.0	Bacteria	ydiA			ko:K03304,ko:K11041	ko05150,map05150				ko00000,ko00001,ko02000,ko02042	2.A.16,2.A.16.1			Bacteria	COG1275@1,COG1275@2	NA|NA|NA	P	C4-dicarboxylate transporter malic acid transport protein
AHPHCOMF_01711	322159.STER_0700	2.4e-203	714.5	Bacilli													Bacteria	1UYHK@1239,4HCT5@91061,COG1960@1,COG1960@2	NA|NA|NA	I	acyl-CoA dehydrogenase
AHPHCOMF_01712	322159.STER_0701	4.5e-97	360.5	Bacteria	mip												Bacteria	COG2128@1,COG2128@2	NA|NA|NA	S	hydroperoxide reductase activity
AHPHCOMF_01713	322159.STER_0702	1.3e-254	885.2	Bacilli	rumA	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.190	ko:K03215					ko00000,ko01000,ko03009				Bacteria	1TP4H@1239,4HA6M@91061,COG2265@1,COG2265@2	NA|NA|NA	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AHPHCOMF_01714	1158606.I579_01885	4.7e-106	391.0	Enterococcaceae													Bacteria	1U2IQ@1239,2E89C@1,30RPR@2,4B4VT@81852,4IC5W@91061	NA|NA|NA		
AHPHCOMF_01715	322159.STER_0705	1e-31	142.1	Bacilli				ko:K07727					ko00000,ko03000				Bacteria	1VEM0@1239,4HQ61@91061,COG3655@1,COG3655@2	NA|NA|NA	K	Cro/C1-type HTH DNA-binding domain
AHPHCOMF_01716	1449342.JQMR01000002_gene24	7.8e-50	203.4	Carnobacteriaceae	dam		2.1.1.72	ko:K06223,ko:K07318	ko03430,map03430				ko00000,ko00001,ko01000,ko02048,ko03032,ko03400				Bacteria	1TRWE@1239,27HF6@186828,4HD84@91061,COG0338@1,COG0338@2,COG3392@1,COG3392@2	NA|NA|NA	L	D12 class N6 adenine-specific DNA methyltransferase
AHPHCOMF_01717	1046629.Ssal_01453	5.7e-34	149.8	Bacilli	estA												Bacteria	1V1CQ@1239,4HGVZ@91061,COG2755@1,COG2755@2	NA|NA|NA	E	GDSL-like Lipase/Acylhydrolase
AHPHCOMF_01718	1046629.Ssal_01451	1.1e-94	352.8	Firmicutes													Bacteria	1VYAW@1239,2F636@1,33YMH@2	NA|NA|NA		
AHPHCOMF_01719	322159.STER_0709	0.0	2092.8	Bacilli	cas9			ko:K09952					ko00000,ko01000,ko02048				Bacteria	1TPSD@1239,4HE0R@91061,COG3513@1,COG3513@2	NA|NA|NA	L	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
AHPHCOMF_01720	264199.stu0658	4.2e-172	610.5	Bacilli	cas1			ko:K15342					ko00000,ko02048,ko03400				Bacteria	1TT0J@1239,4HC5E@91061,COG1518@1,COG1518@2	NA|NA|NA	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AHPHCOMF_01721	264199.stu0659	3.1e-53	214.2	Bacilli	cas2			ko:K09951					ko00000,ko02048				Bacteria	1VEH4@1239,4HNYR@91061,COG3512@1,COG3512@2	NA|NA|NA	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AHPHCOMF_01722	322159.STER_0712	1.7e-193	681.8	Firmicutes													Bacteria	1W43F@1239,2DZ2B@1,34C6V@2	NA|NA|NA	S	CRISPR-associated protein Csn2 subfamily St
AHPHCOMF_01723	264199.stu0661	2.7e-146	524.6	Bacilli	ycgQ			ko:K08986					ko00000				Bacteria	1V3EX@1239,4HGMG@91061,COG3689@1,COG3689@2	NA|NA|NA	S	TIGR03943 family
AHPHCOMF_01724	264199.stu0662	2.1e-155	555.1	Bacilli	XK27_03015			ko:K07089					ko00000				Bacteria	1TQHK@1239,4HB25@91061,COG0701@1,COG0701@2	NA|NA|NA	S	permease
AHPHCOMF_01726	264199.stu0663	0.0	1336.2	Bacilli	yhgF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896		ko:K06959					ko00000				Bacteria	1TPFE@1239,4HAGY@91061,COG2183@1,COG2183@2	NA|NA|NA	K	Transcriptional accessory protein
AHPHCOMF_01727	322159.STER_0718	9.9e-42	175.6	Bacilli	pspC			ko:K03973					ko00000,ko02048,ko03000				Bacteria	1VF0M@1239,4IRAN@91061,COG1983@1,COG1983@2	NA|NA|NA	KT	PspC domain
AHPHCOMF_01728	322159.STER_0719	1e-170	605.9	Bacilli	hprK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464		ko:K06023					ko00000,ko01000				Bacteria	1TP5Z@1239,4HAXR@91061,COG1493@1,COG1493@2	NA|NA|NA	F	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AHPHCOMF_01729	322159.STER_0720	4e-147	527.3	Bacilli	lgt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009898,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576	2.1.1.199	ko:K03438,ko:K13292					ko00000,ko01000,ko03009				Bacteria	1TPAK@1239,4HAT0@91061,COG0682@1,COG0682@2	NA|NA|NA	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AHPHCOMF_01731	322159.STER_0722	2.1e-68	265.0	Bacilli	ytxH												Bacteria	1VFY7@1239,4HNWV@91061,COG4980@1,COG4980@2	NA|NA|NA	S	General stress protein
AHPHCOMF_01733	264199.stu0671	2e-177	628.2	Bacilli	yegQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464		ko:K08303	ko05120,map05120				ko00000,ko00001,ko01000,ko01002				Bacteria	1TQIZ@1239,4HA2T@91061,COG0826@1,COG0826@2	NA|NA|NA	O	Peptidase U32
AHPHCOMF_01734	264199.stu0672	3.4e-252	877.1	Bacilli	yegQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464		ko:K08303	ko05120,map05120				ko00000,ko00001,ko01000,ko01002				Bacteria	1TPRE@1239,4HBEG@91061,COG0826@1,COG0826@2	NA|NA|NA	O	Peptidase U32
AHPHCOMF_01735	435842.HMPREF0848_00340	8.1e-46	189.5	Bacilli													Bacteria	1VB64@1239,4HMGX@91061,COG4357@1,COG4357@2	NA|NA|NA	S	CHY zinc finger
AHPHCOMF_01736	322159.STER_0726	8.4e-88	329.7	Bacilli	bioY			ko:K03523	ko02010,map02010	M00581,M00582			ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2			Bacteria	1VA1G@1239,4HNE8@91061,COG1268@1,COG1268@2	NA|NA|NA	S	biotin synthase
AHPHCOMF_01738	264199.stu0676	1.1e-33	148.7	Bacilli	XK27_12190												Bacteria	1VEFE@1239,4HNSP@91061,COG4443@1,COG4443@2	NA|NA|NA	S	protein conserved in bacteria
AHPHCOMF_01739	322159.STER_0729	5.1e-235	820.1	Bacilli	mntH	GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281		ko:K03322					ko00000,ko02000	2.A.55.2.6,2.A.55.3			Bacteria	1TPT1@1239,4HAEA@91061,COG1914@1,COG1914@2	NA|NA|NA	P	H( )-stimulated, divalent metal cation uptake system
AHPHCOMF_01740	388919.SSA_1657	9.6e-12	76.3	Streptococcus sanguinis													Bacteria	1UA84@1239,1WRWU@1305,29RMD@1,30CQM@2,4IKJF@91061	NA|NA|NA		
AHPHCOMF_01741	264199.stu0679	1.2e-67	262.3	Bacilli	nudG	GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.6.1.55,3.6.1.65	ko:K03574,ko:K08320					ko00000,ko01000,ko03400			iE2348C_1286.E2348C_1887,iECP_1309.ECP_1705,iLF82_1304.LF82_1533,iNRG857_1313.NRG857_08815,iPC815.YPO2167,iSSON_1240.SSON_1397	Bacteria	1V6ET@1239,4HIP6@91061,COG0494@1,COG0494@2	NA|NA|NA	L	Belongs to the Nudix hydrolase family
AHPHCOMF_01742	264199.stu0680	0.0	1374.8	Bacilli													Bacteria	1TQ62@1239,4HAJ1@91061,COG1061@1,COG1061@2	NA|NA|NA	L	helicase
AHPHCOMF_01743	322159.STER_0733	9.9e-288	995.3	Bacilli	lysS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1TP2P@1239,4H9X4@91061,COG1190@1,COG1190@2	NA|NA|NA	J	Belongs to the class-II aminoacyl-tRNA synthetase family
AHPHCOMF_01744	322159.STER_0734	1e-163	583.2	Bacilli													Bacteria	1VWTU@1239,4HX18@91061,COG1388@1,COG1388@2	NA|NA|NA	M	LysM domain
AHPHCOMF_01745	904293.HMPREF9176_0571	7.6e-16	90.5	Bacilli													Bacteria	1VVCA@1239,2BXK6@1,33WGZ@2,4HWEI@91061	NA|NA|NA		
AHPHCOMF_01746	264199.stu0696	7.5e-174	616.3	Bacilli				ko:K07025					ko00000				Bacteria	1V5P7@1239,4HHGY@91061,COG1011@1,COG1011@2	NA|NA|NA	S	hydrolase
AHPHCOMF_01747	322159.STER_0739	6.6e-116	423.3	Bacilli	pgm6		5.4.2.11,5.4.2.12	ko:K01834,ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147				Bacteria	1V6ES@1239,4HJVI@91061,COG0406@1,COG0406@2	NA|NA|NA	G	phosphoglycerate mutase
AHPHCOMF_01748	264199.stu0698	1e-81	309.3	Bacilli	ybaK			ko:K03976					ko00000,ko01000,ko03016				Bacteria	1V6JF@1239,4HIH1@91061,COG2606@1,COG2606@2	NA|NA|NA	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AHPHCOMF_01749	322159.STER_0741	2.8e-155	554.7	Bacilli	XK27_00880		3.5.1.28	ko:K01447,ko:K07273			R04112	RC00064,RC00141	ko00000,ko01000				Bacteria	1V2YH@1239,4HI8U@91061,COG3757@1,COG3757@2	NA|NA|NA	M	Glycosyl hydrolase, family 25
AHPHCOMF_01750	1123304.AQYA01000028_gene1720	2.1e-27	128.6	Bacteria													Bacteria	COG2461@1,COG2461@2	NA|NA|NA	P	Hemerythrin HHE cation binding domain protein
AHPHCOMF_01751	264199.stu0701	2.3e-113	414.8	Bacilli			1.14.14.5	ko:K04091	ko00920,map00920		R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000				Bacteria	1VJRB@1239,4ISN7@91061,COG2141@1,COG2141@2	NA|NA|NA	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AHPHCOMF_01752	904306.HMPREF9192_1160	7.2e-23	112.5	Bacilli	MA20_36090												Bacteria	1VEWD@1239,4IQU0@91061,COG1073@1,COG1073@2	NA|NA|NA	S	Protein of unknown function (DUF2974)
AHPHCOMF_01753	435842.HMPREF0848_00356	1.6e-21	108.2	Bacilli	MA20_36090												Bacteria	1VEWD@1239,4IQU0@91061,COG1073@1,COG1073@2	NA|NA|NA	S	Protein of unknown function (DUF2974)
AHPHCOMF_01754	888049.HMPREF8578_0965	0.0	1645.9	Streptococcus oralis	hsdR		3.1.21.3	ko:K01153					ko00000,ko01000,ko02048				Bacteria	1TP7S@1239,1WQ7Z@1303,4I40R@91061,COG0610@1,COG0610@2	NA|NA|NA	V	Type I restriction enzyme R protein N terminus (HSDR_N)
AHPHCOMF_01755	888049.HMPREF8578_0966	7.3e-289	999.2	Streptococcus oralis	hsdM		2.1.1.72	ko:K03427					ko00000,ko01000,ko02048				Bacteria	1TPGZ@1239,1WPZV@1303,4HA1J@91061,COG0286@1,COG0286@2	NA|NA|NA	V	N-6 DNA Methylase
AHPHCOMF_01756	1114965.Spaf_0639	5.9e-134	484.2	Bacilli	hsdS		3.1.21.3	ko:K01154					ko00000,ko01000,ko02048				Bacteria	1V5F3@1239,4IQS2@91061,COG0732@1,COG0732@2	NA|NA|NA	V	Type I restriction modification DNA specificity domain
AHPHCOMF_01758	889201.HMPREF9422_1246	3e-38	164.5	Firmicutes													Bacteria	1VN4T@1239,2EGRB@1,33AHH@2	NA|NA|NA		
AHPHCOMF_01759	264199.stu0713	1.7e-174	618.6	Bacilli	spd			ko:K15051					ko00000				Bacteria	1TR37@1239,4HK9Z@91061,COG2169@1,COG2169@2	NA|NA|NA	F	DNA RNA non-specific endonuclease
AHPHCOMF_01760	264199.stu0714	1.7e-91	342.0	Bacilli	lemA			ko:K03744					ko00000				Bacteria	1V1G7@1239,4IR1J@91061,COG1704@1,COG1704@2	NA|NA|NA	S	LemA family
AHPHCOMF_01761	322159.STER_0757	9.3e-132	476.5	Bacilli	htpX			ko:K03799		M00743			ko00000,ko00002,ko01000,ko01002				Bacteria	1TP23@1239,4HB11@91061,COG0501@1,COG0501@2	NA|NA|NA	O	Belongs to the peptidase M48B family
AHPHCOMF_01762	264199.stu0716	4.2e-75	287.3	Bacilli				ko:K16924,ko:K16927		M00582			ko00000,ko00002,ko02000	3.A.1.29,3.A.1.32			Bacteria	1V5GD@1239,4HI8Y@91061,COG4720@1,COG4720@2	NA|NA|NA	S	Psort location CytoplasmicMembrane, score
AHPHCOMF_01763	1046629.Ssal_01392	6.2e-56	223.4	Bacilli													Bacteria	1VF26@1239,2DNM7@1,32Y2X@2,4HP82@91061	NA|NA|NA	S	Domain of unknown function (DUF4430)
AHPHCOMF_01764	322159.STER_0760	0.0	1824.7	Bacilli	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000			iJN678.ppc,iSFV_1184.SFV_4025	Bacteria	1TQB6@1239,4HCAF@91061,COG2352@1,COG2352@2	NA|NA|NA	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AHPHCOMF_01765	264199.stu0719	1.2e-183	649.0	Bacilli	holA		2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1TRM0@1239,4HBB4@91061,COG1466@1,COG1466@2	NA|NA|NA	L	DNA polymerase III delta subunit
AHPHCOMF_01766	322159.STER_0762	8.5e-113	412.9	Bacilli	sodA	GO:0005575,GO:0005576	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016				ko00000,ko00001,ko01000				Bacteria	1TPXT@1239,4HA6U@91061,COG0605@1,COG0605@2	NA|NA|NA	C	radicals which are normally produced within the cells and which are toxic to biological systems
AHPHCOMF_01767	322159.STER_0765	2e-186	658.7	Bacilli			3.5.2.6	ko:K01467,ko:K17836	ko00311,ko01130,ko01501,ko02020,map00311,map01130,map01501,map02020	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504				Bacteria	1VHF8@1239,4HU1N@91061,COG2367@1,COG2367@2	NA|NA|NA	V	D-alanyl-D-alanine carboxypeptidase
AHPHCOMF_01768	264199.stu0722	2.2e-114	418.3	Firmicutes	pilD		3.4.23.43	ko:K02236,ko:K02506,ko:K02654		M00331,M00429			ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2			Bacteria	1V91J@1239,COG1989@1,COG1989@2	NA|NA|NA	NOU	Bacterial Peptidase A24 N-terminal domain
AHPHCOMF_01769	322159.STER_0767	3.5e-91	340.9	Bacilli	dps			ko:K04047					ko00000,ko03036				Bacteria	1VCVJ@1239,4HMBD@91061,COG0783@1,COG0783@2	NA|NA|NA	P	Belongs to the Dps family
AHPHCOMF_01770	322159.STER_0768	1.1e-80	305.8	Bacilli	perR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141		ko:K03711,ko:K09825					ko00000,ko03000				Bacteria	1V400@1239,4HHF8@91061,COG0735@1,COG0735@2	NA|NA|NA	P	Belongs to the Fur family
AHPHCOMF_01771	264199.stu0727	8.4e-28	129.0	Bacilli	yqgQ												Bacteria	1VK83@1239,4HRG2@91061,COG4483@1,COG4483@2	NA|NA|NA	S	protein conserved in bacteria
AHPHCOMF_01772	264199.stu0728	2.2e-179	634.8	Bacilli	glk	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000			iSB619.SA_RS07790	Bacteria	1TPKW@1239,4HBAU@91061,COG1940@1,COG1940@2	NA|NA|NA	G	Glucokinase
AHPHCOMF_01773	322159.STER_0771	0.0	1195.6	Bacilli	typA	GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840		ko:K06207					ko00000				Bacteria	1TQ5Y@1239,4HAQ6@91061,COG1217@1,COG1217@2	NA|NA|NA	T	GTP-binding protein TypA
AHPHCOMF_01775	264199.stu0731	4.6e-252	876.7	Bacilli	murD		6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100		R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011				Bacteria	1TQ3P@1239,4HA5P@91061,COG0771@1,COG0771@2	NA|NA|NA	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AHPHCOMF_01776	322159.STER_0774	1e-201	709.1	Bacilli	murG		2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112		R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011		GT28		Bacteria	1TQFT@1239,4HBAQ@91061,COG0707@1,COG0707@2	NA|NA|NA	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AHPHCOMF_01777	264199.stu0733	1.1e-171	609.4	Firmicutes	divIB			ko:K03589	ko04112,map04112				ko00000,ko00001,ko03036				Bacteria	1VHEY@1239,COG1589@1,COG1589@2	NA|NA|NA	D	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
AHPHCOMF_01778	264199.stu0734	8e-252	875.9	Bacilli	ftsA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562		ko:K03590	ko04112,map04112				ko00000,ko00001,ko03036,ko04812				Bacteria	1TP1Z@1239,4H9NF@91061,COG0849@1,COG0849@2	NA|NA|NA	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
AHPHCOMF_01779	264199.stu0735	5.4e-237	826.6	Bacilli	ftsZ	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363		ko:K03531	ko04112,map04112				ko00000,ko00001,ko02048,ko03036,ko04812				Bacteria	1TP6W@1239,4H9WZ@91061,COG0206@1,COG0206@2	NA|NA|NA	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AHPHCOMF_01780	322159.STER_0778	2.7e-123	448.0	Bacilli	ylmE	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363		ko:K06997					ko00000				Bacteria	1TRDN@1239,4HC45@91061,COG0325@1,COG0325@2	NA|NA|NA	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AHPHCOMF_01781	322159.STER_0779	1.4e-96	359.0	Bacteria	sepF	GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0044464,GO:0051301,GO:0071840,GO:0071944,GO:0090529		ko:K09772					ko00000,ko03036				Bacteria	COG1799@1,COG1799@2	NA|NA|NA	D	cell septum assembly
AHPHCOMF_01782	322159.STER_0780	2.6e-34	151.0	Bacteria	yggT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K02221					ko00000,ko02044				Bacteria	COG0762@1,COG0762@2	NA|NA|NA	D	integral membrane protein
AHPHCOMF_01783	322159.STER_0781	1.2e-143	515.8	Bacteria	ylmH			ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507			ko00000,ko00001,ko00002,ko01001,ko02022,ko02035				Bacteria	COG2302@1,COG2302@2	NA|NA|NA	T	S4 RNA-binding domain
AHPHCOMF_01784	322159.STER_0782	1.8e-135	488.8	Bacilli	divIVA			ko:K04074					ko00000,ko03036				Bacteria	1V27M@1239,4HJYN@91061,COG3599@1,COG3599@2	NA|NA|NA	D	Cell division protein DivIVA
AHPHCOMF_01785	322159.STER_0783	0.0	1880.5	Bacilli	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iG2583_1286.G2583_0027,iPC815.YPO0475	Bacteria	1TPS7@1239,4HAWB@91061,COG0060@1,COG0060@2	NA|NA|NA	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AHPHCOMF_01786	322159.STER_0786	1.4e-212	745.3	Bacilli	mntH												Bacteria	1V04N@1239,4HBF6@91061,COG1914@1,COG1914@2	NA|NA|NA	P	Mn2 and Fe2 transporters of the NRAMP family
AHPHCOMF_01787	264199.stu0746	2e-45	188.0	Bacilli	rpmE2	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034224,GO:0034641,GO:0034645,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0120127,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02909	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1VEGU@1239,4HNQF@91061,COG0254@1,COG0254@2	NA|NA|NA	J	50S ribosomal protein L31
AHPHCOMF_01788	264199.stu0747	1.5e-177	628.6	Bacilli	apbE		2.7.1.180	ko:K03734					ko00000,ko01000				Bacteria	1TR9C@1239,4HDFE@91061,COG1477@1,COG1477@2	NA|NA|NA	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
AHPHCOMF_01789	322159.STER_0789	1e-184	652.5	Bacilli	nrnA	GO:0008150,GO:0040007	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120		R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400				Bacteria	1TPXX@1239,4H9ZW@91061,COG0618@1,COG0618@2	NA|NA|NA	S	domain protein
AHPHCOMF_01790	322159.STER_0790	3.1e-155	554.3	Bacilli	gst			ko:K11209					ko00000,ko01000				Bacteria	1TPZ7@1239,4HD0K@91061,COG0625@1,COG0625@2	NA|NA|NA	O	Glutathione S-transferase
AHPHCOMF_01791	322159.STER_0791	2.1e-188	664.8	Bacilli	add		3.5.4.4	ko:K01488,ko:K02029	ko00230,ko01100,ko05340,map00230,map01100,map05340	M00236	R01560,R02556	RC00477	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3		iHN637.CLJU_RS13960	Bacteria	1U44B@1239,4HCES@91061,COG1816@1,COG1816@2	NA|NA|NA	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AHPHCOMF_01792	264199.stu0751	2.4e-112	411.4	Bacilli	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100		R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000			iAF1260.b1238,iBWG_1329.BWG_1065,iECDH10B_1368.ECDH10B_1298,iECDH1ME8569_1439.ECDH1ME8569_1176,iEcDH1_1363.EcDH1_2411,iJO1366.b1238,iJR904.b1238,iPC815.YPO2176,iY75_1357.Y75_RS06470	Bacteria	1TRVM@1239,4HA4A@91061,COG1435@1,COG1435@2	NA|NA|NA	F	thymidine kinase
AHPHCOMF_01793	264199.stu0752	3e-193	681.0	Bacilli	prfA			ko:K02835					ko00000,ko03012				Bacteria	1TQ7V@1239,4H9MB@91061,COG0216@1,COG0216@2	NA|NA|NA	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AHPHCOMF_01794	322159.STER_0794	1.2e-154	552.4	Bacilli	prmB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009007,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0032775,GO:0034641,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044728,GO:0046483,GO:0071704,GO:0090304,GO:0140096,GO:0140097,GO:1901360,GO:1901564	2.1.1.297,2.1.1.298	ko:K02493,ko:K07320			R10806	RC00003,RC03279	ko00000,ko01000,ko03009,ko03012				Bacteria	1TSMA@1239,4HC6W@91061,COG2890@1,COG2890@2	NA|NA|NA	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
AHPHCOMF_01795	264199.stu0754	9.7e-109	399.4	Bacilli	ywlC	GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	2.7.7.87,3.1.3.48	ko:K01104,ko:K07566			R10463	RC00745	ko00000,ko01000,ko03009,ko03016				Bacteria	1TP1I@1239,4HA7W@91061,COG0009@1,COG0009@2	NA|NA|NA	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
AHPHCOMF_01796	322159.STER_0796	1.8e-234	818.1	Bacilli	glyA		2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQVM@1239,4HA5K@91061,COG0112@1,COG0112@2	NA|NA|NA	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AHPHCOMF_01797	264199.stu0756	1.2e-177	629.0	Bacilli	ndpA	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003727,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0009295,GO:0042802,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0097159,GO:1901363		ko:K06899					ko00000,ko03036				Bacteria	1V437@1239,4IQXJ@91061,COG3081@1,COG3081@2	NA|NA|NA	S	37-kD nucleoid-associated bacterial protein
AHPHCOMF_01798	264199.stu0757	6.6e-105	386.7	Bacteria	pvaA			ko:K02395					ko00000,ko02035				Bacteria	COG0741@1,COG0741@2	NA|NA|NA	M	lytic transglycosylase activity
AHPHCOMF_01799	322159.STER_0799	0.0	1087.8	Bacilli	yfiB1			ko:K06147,ko:K06148,ko:K18887	ko02010,map02010	M00706			ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21			Bacteria	1TP0B@1239,4H9SC@91061,COG1132@1,COG1132@2	NA|NA|NA	V	abc transporter atp-binding protein
AHPHCOMF_01800	322159.STER_0800	0.0	1103.6	Bacilli	XK27_10035			ko:K06147,ko:K11085	ko02010,map02010				ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21			Bacteria	1TP0B@1239,4HCVN@91061,COG1132@1,COG1132@2	NA|NA|NA	V	abc transporter atp-binding protein
AHPHCOMF_01801	1000570.HMPREF9966_1459	1.7e-09	68.6	Streptococcus anginosus group													Bacteria	1TW0K@1239,2DIU2@1,3044G@2,42EHI@671232,4I4PC@91061	NA|NA|NA	S	D-Ala-teichoic acid biosynthesis protein
AHPHCOMF_01802	322159.STER_0802	1.4e-297	1028.1	Bacilli	dltA	GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016208,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0022857,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.13	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	M00725	R02718	RC00037,RC00094	ko00000,ko00001,ko00002,ko01000,ko01504				Bacteria	1TPTH@1239,4HAHU@91061,COG1020@1,COG1020@2	NA|NA|NA	Q	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AHPHCOMF_01803	264199.stu0762	3.9e-237	827.0	Bacilli	dltB			ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725			ko00000,ko00001,ko00002,ko01504				Bacteria	1TP52@1239,4HBQG@91061,COG1696@1,COG1696@2	NA|NA|NA	M	Membrane protein involved in D-alanine export
AHPHCOMF_01804	264199.stu0763	1.7e-35	154.8	Bacilli	dltC	GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.1.1.13	ko:K02078,ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	M00725	R02718	RC00037,RC00094	ko00000,ko00001,ko00002,ko01000,ko01504				Bacteria	1VFQI@1239,4HNIH@91061,COG0236@1,COG0236@2	NA|NA|NA	IQ	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AHPHCOMF_01805	322159.STER_0805	3.6e-230	803.9	Bacilli	dltD			ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725			ko00000,ko00001,ko00002,ko01504				Bacteria	1TSZU@1239,4HC3H@91061,COG3966@1,COG3966@2	NA|NA|NA	M	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AHPHCOMF_01806	264199.stu0765	1.2e-32	145.2	Firmicutes				ko:K07497					ko00000				Bacteria	1TQQY@1239,COG2801@1,COG2801@2	NA|NA|NA	L	Integrase core domain protein
AHPHCOMF_01807	888048.HMPREF8577_0808	8.7e-67	259.6	Bacilli				ko:K07497					ko00000				Bacteria	1TQQY@1239,4HC8M@91061,COG2801@1,COG2801@2	NA|NA|NA	L	Transposase and inactivated derivatives
AHPHCOMF_01808	322159.STER_0055	8.3e-18	95.5	Bacteria				ko:K07483					ko00000				Bacteria	COG2963@1,COG2963@2	NA|NA|NA	L	transposase activity
AHPHCOMF_01809	322159.STER_0016	5.2e-38	163.3	Firmicutes				ko:K07483					ko00000				Bacteria	1W68S@1239,COG2963@1,COG2963@2	NA|NA|NA	L	Transposase
AHPHCOMF_01810	264199.stu0770	0.0	1638.6	Bacilli			3.6.3.8	ko:K01537,ko:K12955					ko00000,ko01000	3.A.3.2,3.A.3.24			Bacteria	1TPF5@1239,4H9S5@91061,COG0474@1,COG0474@2	NA|NA|NA	P	cation transport ATPase
AHPHCOMF_01811	322159.STER_0809	0.0	1147.9	Bacilli	pabB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.6.1.85,4.1.3.27,4.1.3.38	ko:K01665,ko:K02619,ko:K03342,ko:K13503,ko:K13950	ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00400,map00790,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01716,R05553	RC00010,RC01418,RC01843,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	1TQAP@1239,4HBKC@91061,COG0115@1,COG0115@2,COG0147@1,COG0147@2	NA|NA|NA	EH	component I
AHPHCOMF_01813	264199.stu0785	0.0	1498.4	Bacilli	metE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0030312,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0040007,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0071944,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000			iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131	Bacteria	1TP2H@1239,4H9QC@91061,COG0620@1,COG0620@2	NA|NA|NA	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AHPHCOMF_01814	322159.STER_0832	7.3e-166	589.7	Firmicutes	metF	GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.5.1.20	ko:K00297,ko:K21010	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,ko02025,map00670,map00720,map01100,map01120,map01200,map01523,map02025	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000			iPC815.YPO0117,iSBO_1134.SBO_3961	Bacteria	1TQFE@1239,COG0685@1,COG0685@2	NA|NA|NA	E	reductase
AHPHCOMF_01815	322159.STER_0833	0.0	1127.1	Bacilli	pgm	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP2N@1239,4HADU@91061,COG1109@1,COG1109@2	NA|NA|NA	G	Phosphoglucomutase
AHPHCOMF_01816	322159.STER_0834	1.7e-94	352.1	Bacilli	panT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944											Bacteria	1V2M1@1239,4HFPD@91061,COG4684@1,COG4684@2	NA|NA|NA	S	ECF transporter, substrate-specific component
AHPHCOMF_01817	264199.stu0789	4.8e-94	350.5	Bacilli	coaBC		4.1.1.36,6.3.2.5	ko:K01598,ko:K13038,ko:K21977	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPP3@1239,4HAK8@91061,COG0452@1,COG0452@2	NA|NA|NA	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AHPHCOMF_01818	264199.stu0790	1.2e-120	439.1	Bacilli	coaB		4.1.1.36,6.3.2.5	ko:K01598,ko:K13038,ko:K21977	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000				Bacteria	1V7YG@1239,4HMIF@91061,COG0452@1,COG0452@2	NA|NA|NA	H	Phosphopantothenate-cysteine ligase
AHPHCOMF_01819	322159.STER_0837	0.0	1092.4	Bacilli	fhs	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP6N@1239,4HA2X@91061,COG2759@1,COG2759@2	NA|NA|NA	F	Belongs to the formate--tetrahydrofolate ligase family
AHPHCOMF_01820	264199.stu0792	6.4e-66	256.5	Bacilli													Bacteria	1V295@1239,4HG3X@91061,COG0745@1,COG0745@2	NA|NA|NA	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AHPHCOMF_01821	904306.HMPREF9192_1234	2.8e-40	171.0	Bacilli													Bacteria	1UHNC@1239,4IS4A@91061,COG0642@1,COG2205@2	NA|NA|NA	T	PhoQ Sensor
AHPHCOMF_01822	904306.HMPREF9192_1234	2.2e-43	181.4	Bacilli													Bacteria	1UHNC@1239,4IS4A@91061,COG0642@1,COG2205@2	NA|NA|NA	T	PhoQ Sensor
AHPHCOMF_01823	264199.stu0795	3.6e-88	330.9	Bacilli													Bacteria	1UHNC@1239,4IS4A@91061,COG0642@1,COG2205@2	NA|NA|NA	T	PhoQ Sensor
AHPHCOMF_01824	322159.STER_0111	6.7e-122	443.4	Bacilli				ko:K07483					ko00000				Bacteria	1V4FD@1239,4IQ19@91061,COG2963@1,COG2963@2	NA|NA|NA	L	Helix-turn-helix domain
AHPHCOMF_01825	264199.stu0796	1.2e-165	589.0	Firmicutes													Bacteria	1TQEG@1239,COG2801@1,COG2801@2	NA|NA|NA	L	integrase core domain
AHPHCOMF_01826	1116231.SMA_0720	1.1e-220	772.3	Bacilli													Bacteria	1TQ93@1239,4HJK9@91061,COG3464@1,COG3464@2	NA|NA|NA	L	Transposase
AHPHCOMF_01827	1214166.ALLG01000021_gene179	1.7e-28	131.3	Streptococcus suis	potC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008519,GO:0015075,GO:0015101,GO:0015203,GO:0015399,GO:0015405,GO:0015417,GO:0015595,GO:0015606,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0015848,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072488,GO:0098533,GO:0098655,GO:0098796,GO:0098797,GO:1902047,GO:1902494,GO:1902495,GO:1903711,GO:1904949,GO:1990351		ko:K11070	ko02010,map02010	M00299			ko00000,ko00001,ko00002,ko02000	3.A.1.11.1		iSBO_1134.SBO_1939	Bacteria	1V0VD@1239,1WT2W@1307,4H9ZC@91061,COG1177@1,COG1177@2	NA|NA|NA	P	Binding-protein-dependent transport system inner membrane component
AHPHCOMF_01828	322159.STER_0844	8.9e-206	722.6	Bacilli	potD			ko:K11069	ko02010,map02010	M00299			ko00000,ko00001,ko00002,ko02000	3.A.1.11.1		iSB619.SA_RS05395	Bacteria	1TPY1@1239,4HAET@91061,COG0687@1,COG0687@2	NA|NA|NA	P	spermidine putrescine ABC transporter
AHPHCOMF_01829	322159.STER_0845	3.1e-268	930.6	Bacilli	clcA	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006821,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015672,GO:0015698,GO:0015706,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0031404,GO:0034220,GO:0042802,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071705,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600		ko:K03281					ko00000	2.A.49		iAF1260.b0155,iB21_1397.B21_00153,iBWG_1329.BWG_0148,iE2348C_1286.E2348C_0162,iEC042_1314.EC042_0155,iEC55989_1330.EC55989_0149,iECBD_1354.ECBD_3463,iECDH10B_1368.ECDH10B_0135,iECDH1ME8569_1439.ECDH1ME8569_0149,iECD_1391.ECD_00154,iECIAI1_1343.ECIAI1_0153,iECO103_1326.ECO103_0155,iECSE_1348.ECSE_0156,iECUMN_1333.ECUMN_0152,iECW_1372.ECW_m0152,iEKO11_1354.EKO11_3761,iETEC_1333.ETEC_0151,iEcDH1_1363.EcDH1_3447,iEcE24377_1341.EcE24377A_0160,iEcolC_1368.EcolC_3504,iJO1366.b0155,iSSON_1240.SSON_0167,iUMNK88_1353.UMNK88_159,iWFL_1372.ECW_m0152,iY75_1357.Y75_RS00790,iZ_1308.Z0166	Bacteria	1TPX0@1239,4HD2H@91061,COG0038@1,COG0038@2	NA|NA|NA	P	Chloride transporter, ClC family
AHPHCOMF_01830	322159.STER_0846	0.0	2941.4	Bacilli	prtS		3.4.21.96	ko:K01361,ko:K17734					ko00000,ko01000,ko01002,ko03110				Bacteria	1TPH1@1239,4HBQH@91061,COG1196@1,COG1196@2,COG1404@1,COG1404@2	NA|NA|NA	O	Belongs to the peptidase S8 family
AHPHCOMF_01831	322159.STER_0847	2.3e-106	391.7	Bacilli				ko:K07483					ko00000				Bacteria	1V4FD@1239,4IQ19@91061,COG2963@1,COG2963@2	NA|NA|NA	L	Helix-turn-helix domain
AHPHCOMF_01832	322159.STER_0848	9.8e-163	579.3	Bacilli													Bacteria	1TQEG@1239,4HD6M@91061,COG2801@1,COG2801@2	NA|NA|NA	L	Integrase core domain protein
AHPHCOMF_01833	322159.STER_1692	6.2e-249	866.3	Bacilli				ko:K07485					ko00000				Bacteria	1TQ93@1239,4HJK9@91061,COG3464@1,COG3464@2	NA|NA|NA	L	Transposase
AHPHCOMF_01834	264199.stu0798	2.1e-30	137.9	Bacteria	rpsT	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02968	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	COG0268@1,COG0268@2	NA|NA|NA	J	rRNA binding
AHPHCOMF_01835	322159.STER_0851	1.9e-172	611.7	Bacilli	coaA	GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.33	ko:K00867	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000			iECDH1ME8569_1439.ECDH1ME8569_3838,iECH74115_1262.ECH74115_5439,iECSE_1348.ECSE_4265,iECSF_1327.ECSF_3833,iECSP_1301.ECSP_5045,iECW_1372.ECW_m4332,iEcDH1_1363.EcDH1_4016,iEcolC_1368.EcolC_4046,iPC815.YPO3758,iSFV_1184.SFV_4047,iSFxv_1172.SFxv_4418,iWFL_1372.ECW_m4332,iZ_1308.Z5545	Bacteria	1TPHJ@1239,4HA4K@91061,COG1072@1,COG1072@2	NA|NA|NA	F	Pantothenic acid kinase
AHPHCOMF_01836	322159.STER_0852	1.8e-107	395.2	Bacilli	rsmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	2.1.1.172	ko:K00564			R07234	RC00003	ko00000,ko01000,ko03009				Bacteria	1V3JX@1239,4IR00@91061,COG2813@1,COG2813@2	NA|NA|NA	J	Methyltransferase small domain protein
AHPHCOMF_01837	1046629.Ssal_00947	1.2e-57	229.2	Bacilli	pdp	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016757,GO:0016758,GO:0044424,GO:0044444,GO:0044464	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219		R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000				Bacteria	1TPCH@1239,4H9NP@91061,COG0213@1,COG0213@2	NA|NA|NA	F	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
AHPHCOMF_01838	435842.HMPREF0848_00806	1.3e-97	362.8	Bacilli	pdp	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016757,GO:0016758,GO:0044424,GO:0044444,GO:0044464	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219		R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000				Bacteria	1TPCH@1239,4H9NP@91061,COG0213@1,COG0213@2	NA|NA|NA	F	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
AHPHCOMF_01839	1046629.Ssal_00948	1.4e-22	111.7	Bacilli	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4,5.4.2.8	ko:K01619,ko:K01840	ko00030,ko00051,ko00520,ko01100,ko01110,ko01130,map00030,map00051,map00520,map01100,map01110,map01130	M00114	R01066,R01818	RC00408,RC00436,RC00437	ko00000,ko00001,ko00002,ko01000			iSB619.SA_RS00835	Bacteria	1TPAJ@1239,4HAAJ@91061,COG0274@1,COG0274@2	NA|NA|NA	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AHPHCOMF_01840	264199.stu0806	4e-63	247.3	Bacilli	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4,5.4.2.8	ko:K01619,ko:K01840	ko00030,ko00051,ko00520,ko01100,ko01110,ko01130,map00030,map00051,map00520,map01100,map01110,map01130	M00114	R01066,R01818	RC00408,RC00436,RC00437	ko00000,ko00001,ko00002,ko01000			iSB619.SA_RS00835	Bacteria	1TPAJ@1239,4HAAJ@91061,COG0274@1,COG0274@2	NA|NA|NA	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AHPHCOMF_01841	322159.STER_0855	1.3e-69	268.9	Bacilli	cdd		2.4.2.2,3.5.4.5	ko:K00756,ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100		R01570,R01876,R01878,R02296,R02484,R02485,R08221	RC00063,RC00074,RC00514	ko00000,ko00001,ko01000			iSB619.SA_RS07895	Bacteria	1V6IP@1239,4HIJ3@91061,COG0295@1,COG0295@2	NA|NA|NA	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
AHPHCOMF_01842	322159.STER_0856	9.5e-192	676.0	Bacilli	tcsA			ko:K02058,ko:K07335		M00221			ko00000,ko00002,ko02000	3.A.1.2			Bacteria	1TPEU@1239,4HANH@91061,COG1744@1,COG1744@2	NA|NA|NA	S	ABC-type transport system, periplasmic component surface lipoprotein
AHPHCOMF_01843	322159.STER_0857	3.7e-282	976.9	Bacilli	xylG		3.6.3.17	ko:K02056,ko:K06400		M00221			ko00000,ko00002,ko01000,ko02000	3.A.1.2			Bacteria	1UYQA@1239,4HVSH@91061,COG3845@1,COG3845@2	NA|NA|NA	S	ABC transporter, ATP-binding protein
AHPHCOMF_01844	322159.STER_0858	3e-190	671.0	Bacilli	yufP	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944		ko:K02057		M00221			ko00000,ko00002,ko02000	3.A.1.2			Bacteria	1TP1F@1239,4H9VE@91061,COG4603@1,COG4603@2	NA|NA|NA	S	Belongs to the binding-protein-dependent transport system permease family
AHPHCOMF_01845	322159.STER_0859	4.8e-171	607.1	Bacilli	yufQ			ko:K02057		M00221			ko00000,ko00002,ko02000	3.A.1.2			Bacteria	1TP8Y@1239,4HAX4@91061,COG1079@1,COG1079@2	NA|NA|NA	S	Belongs to the binding-protein-dependent transport system permease family
AHPHCOMF_01846	264199.stu0812	1.2e-120	439.1	Bacilli	ycbL	GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615	3.1.2.6	ko:K01069	ko00620,map00620		R01736	RC00004,RC00137	ko00000,ko00001,ko01000				Bacteria	1V6FA@1239,4HHRQ@91061,COG0491@1,COG0491@2	NA|NA|NA	S	COG0491 Zn-dependent hydrolases, including glyoxylases
AHPHCOMF_01847	904306.HMPREF9192_1246	0.0	1498.4	Bacilli	dinG	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7,3.6.4.12	ko:K02342,ko:K03722	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1TQHQ@1239,4HB2Y@91061,COG1199@1,COG1199@2,COG2176@1,COG2176@2	NA|NA|NA	L	helicase involved in DNA repair and perhaps also replication
AHPHCOMF_01848	322159.STER_0862	6.8e-81	306.6	Bacilli	ypmB												Bacteria	1VA2H@1239,4HNMM@91061,COG5353@1,COG5353@2	NA|NA|NA	S	Protein conserved in bacteria
AHPHCOMF_01849	264199.stu0817	1.6e-216	758.4	Bacilli	aspB	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297	2.6.1.1,2.6.1.14	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230		R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052	RC00006,RC00025	ko00000,ko00001,ko01000,ko01007			iHN637.CLJU_RS06550	Bacteria	1TP0J@1239,4HA13@91061,COG0436@1,COG0436@2	NA|NA|NA	E	Aminotransferase
AHPHCOMF_01850	322159.STER_0864	2.4e-261	907.5	Bacilli	asnS	GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1TP38@1239,4H9YH@91061,COG0017@1,COG0017@2	NA|NA|NA	J	Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
AHPHCOMF_01851	562983.HMPREF0433_01645	1.5e-07	62.0	Bacilli													Bacteria	1W2BC@1239,2DF7W@1,2ZQU2@2,4HZFK@91061	NA|NA|NA		
AHPHCOMF_01852	264199.stu1302	2.4e-30	137.5	Bacteria													Bacteria	COG3464@1,COG3464@2	NA|NA|NA		
AHPHCOMF_01853	904306.HMPREF9192_0265	3e-13	80.1	Bacteria													Bacteria	COG3464@1,COG3464@2	NA|NA|NA		
AHPHCOMF_01854	264199.stu0824	3e-63	247.7	Bacilli	tdcF		3.5.99.10	ko:K09022			R11098,R11099	RC03275,RC03354	ko00000,ko01000				Bacteria	1V6HG@1239,4HKEF@91061,COG0251@1,COG0251@2	NA|NA|NA	J	endoribonuclease L-PSP
AHPHCOMF_01855	264199.stu0825	1.5e-123	448.7	Bacilli	queC		6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100		R09978	RC00959	ko00000,ko00001,ko01000,ko03016				Bacteria	1TP4Z@1239,4HB1Y@91061,COG0603@1,COG0603@2	NA|NA|NA	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AHPHCOMF_01856	264199.stu0826	3.7e-81	307.4	Bacilli	queD		4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016				Bacteria	1V9HU@1239,4HJEX@91061,COG0720@1,COG0720@2	NA|NA|NA	H	synthase
AHPHCOMF_01857	264199.stu0827	4.6e-134	483.8	Bacilli	queE	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047	1.97.1.4,4.3.99.3	ko:K04068,ko:K10026	ko00790,ko01100,map00790,map01100		R04710,R10002	RC02989	ko00000,ko00001,ko01000,ko03016				Bacteria	1TQ58@1239,4HAJ3@91061,COG0602@1,COG0602@2	NA|NA|NA	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
AHPHCOMF_01858	264199.stu0828	6.5e-95	353.2	Bacilli	queF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016651,GO:0016657,GO:0018130,GO:0019438,GO:0033739,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.7.1.13	ko:K06879,ko:K09457	ko00790,ko01100,map00790,map01100		R07605	RC01875	ko00000,ko00001,ko01000,ko03016			iSFV_1184.SFV_2663,iSF_1195.SF2807,iS_1188.S3002	Bacteria	1TPYC@1239,4HB14@91061,COG0780@1,COG0780@2	NA|NA|NA	S	Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
AHPHCOMF_01859	1046629.Ssal_00969	2.2e-19	100.9	Bacteria													Bacteria	COG1196@1,COG1196@2	NA|NA|NA	D	nuclear chromosome segregation
AHPHCOMF_01860	322159.STER_0874	2e-135	488.4	Bacilli	yejC												Bacteria	1V46X@1239,4HI49@91061,COG4420@1,COG4420@2	NA|NA|NA	S	cyclic nucleotide-binding protein
AHPHCOMF_01861	264199.stu0831	1.2e-163	582.4	Bacilli	rapZ	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363		ko:K06958					ko00000,ko03019				Bacteria	1TPS4@1239,4H9KM@91061,COG1660@1,COG1660@2	NA|NA|NA	S	Displays ATPase and GTPase activities
AHPHCOMF_01862	322159.STER_0876	3.6e-182	644.0	Bacilli	ybhK												Bacteria	1TPNV@1239,4HA0Z@91061,COG0391@1,COG0391@2	NA|NA|NA	S	Required for morphogenesis under gluconeogenic growth conditions
AHPHCOMF_01863	264199.stu0833	8.7e-162	576.2	Bacilli	whiA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944		ko:K09762					ko00000				Bacteria	1TP2X@1239,4HB4H@91061,COG1481@1,COG1481@2	NA|NA|NA	K	May be required for sporulation
AHPHCOMF_01864	904306.HMPREF9192_1264	2.1e-185	654.8	Bacilli	pepD			ko:K08659					ko00000,ko01000,ko01002				Bacteria	1TQ0F@1239,4HC3G@91061,COG4690@1,COG4690@2	NA|NA|NA	E	Dipeptidase
AHPHCOMF_01865	322159.STER_0879	5.4e-32	142.9	Bacilli	cspD	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006275,GO:0006355,GO:0006950,GO:0008150,GO:0008156,GO:0009266,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2000113,GO:2001141		ko:K03704					ko00000,ko03000				Bacteria	1W15H@1239,4HXYN@91061,COG1278@1,COG1278@2	NA|NA|NA	K	Cold shock protein domain
AHPHCOMF_01866	264199.stu0838	8e-42	176.0	Bacilli				ko:K03704					ko00000,ko03000				Bacteria	1VEE0@1239,4HNJC@91061,COG1278@1,COG1278@2	NA|NA|NA	K	Cold-Shock Protein
AHPHCOMF_01867	322159.STER_0881	3.6e-224	783.9	Bacilli				ko:K07493					ko00000				Bacteria	1TP4C@1239,4HC5W@91061,COG3328@1,COG3328@2	NA|NA|NA	L	Transposase, Mutator family
AHPHCOMF_01868	264199.stu0840	0.0	1159.4	Bacilli	copB		3.6.3.4	ko:K01533			R00086	RC00002	ko00000,ko01000	3.A.3.5			Bacteria	1TP5S@1239,4HAI0@91061,COG2217@1,COG2217@2	NA|NA|NA	P	P-type ATPase
AHPHCOMF_01869	322159.STER_0883	3.3e-222	777.3	Bacilli				ko:K07493					ko00000				Bacteria	1TP4C@1239,4HC5W@91061,COG3328@1,COG3328@2	NA|NA|NA	L	Transposase, Mutator family
AHPHCOMF_01870	264199.stu0844	4.4e-194	683.7	Bacilli			3.1.21.3	ko:K01153					ko00000,ko01000,ko02048				Bacteria	1TP7S@1239,4HB5A@91061,COG0610@1,COG0610@2	NA|NA|NA	L	Subunit R is required for both nuclease and ATPase activities, but not for modification
AHPHCOMF_01871	264199.stu0846	2.3e-170	604.7	Bacilli	mccA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042127,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0065007,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.134,2.5.1.47	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00609	R00897,R03601,R04859,R10305	RC00020,RC00069,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000			iSB619.SA_RS02385	Bacteria	1TP30@1239,4HAMU@91061,COG0031@1,COG0031@2	NA|NA|NA	E	Belongs to the cysteine synthase cystathionine beta- synthase family
AHPHCOMF_01872	322159.STER_0886	9.1e-220	769.2	Bacilli	metC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.5.1.48,4.4.1.1,4.4.1.2,4.4.1.8	ko:K01739,ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00609	R00782,R00999,R01001,R01283,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPC7@1239,4HAFQ@91061,COG0626@1,COG0626@2	NA|NA|NA	E	cystathionine
AHPHCOMF_01873	405566.lhv_1903	1.5e-95	355.5	Lactobacillaceae	cysE		2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000				Bacteria	1TR42@1239,3F63E@33958,4HAKS@91061,COG1045@1,COG1045@2	NA|NA|NA	E	Bacterial transferase hexapeptide (six repeats)
AHPHCOMF_01874	264199.stu0839	6.6e-94	350.1	Bacilli				ko:K07493					ko00000				Bacteria	1TP4C@1239,4HAXJ@91061,COG3328@1,COG3328@2	NA|NA|NA	L	Transposase
AHPHCOMF_01875	1116231.SMA_1382	7.1e-89	333.2	Bacilli													Bacteria	1TP4C@1239,4HAXJ@91061,COG3328@1,COG3328@2	NA|NA|NA	L	Transposase
AHPHCOMF_01876	264199.stu0851	3.7e-54	217.2	Bacteria	hsdS		2.1.1.72,3.1.21.3	ko:K01154,ko:K07317					ko00000,ko01000,ko02048				Bacteria	COG0732@1,COG0732@2	NA|NA|NA	V	type I restriction modification DNA specificity domain
AHPHCOMF_01877	264199.stu0852	1.7e-111	408.7	Bacilli	hsdM		2.1.1.72	ko:K03427					ko00000,ko01000,ko02048				Bacteria	1TPGZ@1239,4HA1J@91061,COG0286@1,COG0286@2	NA|NA|NA	V	type I restriction-modification system
AHPHCOMF_01878	264199.stu0855	1.2e-155	555.8	Bacilli	glcU			ko:K05340					ko00000,ko02000	2.A.7.5			Bacteria	1TQBN@1239,4HAVH@91061,COG4975@1,COG4975@2	NA|NA|NA	U	Glucose uptake
AHPHCOMF_01879	1423754.BALY01000004_gene1528	1.1e-08	65.5	Lactobacillaceae	mycA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005504,GO:0005515,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0031406,GO:0032787,GO:0033293,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046983,GO:0048037,GO:0050151,GO:0050660,GO:0050662,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901363	4.2.1.53	ko:K10254					ko00000,ko01000				Bacteria	1TQZ6@1239,3F3QX@33958,4HAYH@91061,COG4716@1,COG4716@2	NA|NA|NA	S	Myosin-crossreactive antigen
AHPHCOMF_01880	272623.L0309	1.2e-79	302.4	Lactococcus	hsdM		2.1.1.72	ko:K03427					ko00000,ko01000,ko02048				Bacteria	1TPGZ@1239,1YB9T@1357,4HA1J@91061,COG0286@1,COG0286@2	NA|NA|NA	V	HsdM N-terminal domain
AHPHCOMF_01881	264199.stu0859	1.3e-88	332.4	Bacteria	XK27_10720												Bacteria	COG2339@1,COG2339@2	NA|NA|NA	D	peptidase activity
AHPHCOMF_01882	264199.stu0860	4e-292	1010.0	Bacilli	adcA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0007154,GO:0008150,GO:0008270,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0030288,GO:0030313,GO:0031667,GO:0031668,GO:0031669,GO:0031975,GO:0033554,GO:0034224,GO:0042221,GO:0042594,GO:0042597,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046686,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0120127		ko:K09815	ko02010,map02010	M00242			ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5			Bacteria	1TPG7@1239,4H9UN@91061,COG0803@1,COG0803@2,COG3443@1,COG3443@2	NA|NA|NA	P	Belongs to the bacterial solute-binding protein 9 family
AHPHCOMF_01883	663952.SDD27957_05960	1.7e-08	65.9	Streptococcus dysgalactiae group													Bacteria	1M9M6@119603,1TXBA@1239,2DJ70@1,304WJ@2,4I68X@91061	NA|NA|NA		
AHPHCOMF_01885	322159.STER_0898	1.1e-170	605.9	Firmicutes	yeiH												Bacteria	1TQYA@1239,COG2855@1,COG2855@2	NA|NA|NA	S	Membrane
AHPHCOMF_01886	904306.HMPREF9192_1840	3e-117	427.9	Bacilli	mur1			ko:K02395					ko00000,ko02035				Bacteria	1UYRM@1239,4HAU6@91061,COG1705@1,COG1705@2	NA|NA|NA	NU	muramidase
AHPHCOMF_01887	264199.stu1454	1.6e-19	101.7	Bacteria				ko:K07483					ko00000				Bacteria	COG2963@1,COG2963@2	NA|NA|NA	L	transposase activity
AHPHCOMF_01888	264199.stu0871	4.3e-70	270.8	Bacteria				ko:K07497					ko00000				Bacteria	COG2801@1,COG2801@2	NA|NA|NA	L	transposition
AHPHCOMF_01889	322159.STER_0901	4.5e-166	590.5	Bacilli	cpsY												Bacteria	1TP3E@1239,4HC5J@91061,COG0583@1,COG0583@2	NA|NA|NA	K	Transcriptional regulator
AHPHCOMF_01890	322159.STER_0903	0.0	1165.6	Bacilli	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931		R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002			iNJ661.Rv3436c,iSB619.SA_RS11245,iYO844.BSU01780	Bacteria	1TPGU@1239,4H9R4@91061,COG0449@1,COG0449@2	NA|NA|NA	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
AHPHCOMF_01891	322159.STER_0904	2.5e-58	231.1	Bacilli	phnA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464		ko:K06193	ko01120,map01120				ko00000				Bacteria	1V6NA@1239,4HIKN@91061,COG2824@1,COG2824@2	NA|NA|NA	P	Alkylphosphonate utilization operon protein PhnA
AHPHCOMF_01892	322159.STER_0905	4e-105	387.5	Bacilli	artQ			ko:K02029,ko:K02030,ko:K17073,ko:K17074	ko02010,map02010	M00236,M00589			ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.20			Bacteria	1V280@1239,4HGMH@91061,COG0765@1,COG0765@2	NA|NA|NA	P	ABC transporter (Permease
AHPHCOMF_01893	264199.stu0876	1.5e-112	412.1	Bacteria	glnQ		3.6.3.21	ko:K02028		M00236			ko00000,ko00002,ko01000,ko02000	3.A.1.3			Bacteria	COG1126@1,COG1126@2	NA|NA|NA	E	abc transporter atp-binding protein
AHPHCOMF_01894	322159.STER_0907	1.2e-157	562.4	Firmicutes	aatB			ko:K02029,ko:K02030		M00236			ko00000,ko00002,ko02000	3.A.1.3			Bacteria	1TQNR@1239,COG0834@1,COG0834@2	NA|NA|NA	ET	ABC transporter substrate-binding protein
AHPHCOMF_01895	264199.stu0879	7.4e-144	516.5	Bacilli	uvrX		2.7.7.7	ko:K02346,ko:K03502,ko:K14161					ko00000,ko01000,ko03400				Bacteria	1TP42@1239,4HA1P@91061,COG0389@1,COG0389@2	NA|NA|NA	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AHPHCOMF_01896	264199.stu0880	8e-58	229.6	Bacilli	adhP	GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0006081,GO:0006117,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009636,GO:0009987,GO:0010033,GO:0016491,GO:0016614,GO:0016616,GO:0033554,GO:0042221,GO:0042493,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0045471,GO:0046185,GO:0046187,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0097305,GO:1901575,GO:1901700	1.1.1.1	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220		R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000			iECP_1309.ECP_1480	Bacteria	1TP5B@1239,4HA9Z@91061,COG1064@1,COG1064@2	NA|NA|NA	C	alcohol dehydrogenase
AHPHCOMF_01897	904306.HMPREF9192_1827	4.2e-113	414.1	Bacilli	adhP	GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0006081,GO:0006117,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009636,GO:0009987,GO:0010033,GO:0016491,GO:0016614,GO:0016616,GO:0033554,GO:0042221,GO:0042493,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0045471,GO:0046185,GO:0046187,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0097305,GO:1901575,GO:1901700	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220		R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000			iECP_1309.ECP_1480	Bacteria	1TP5B@1239,4HA9Z@91061,COG1064@1,COG1064@2	NA|NA|NA	C	alcohol dehydrogenase
AHPHCOMF_01898	1116231.SMA_0980	8.8e-21	106.3	Bacilli													Bacteria	1W1ET@1239,2DY2G@1,347TK@2,4HYVW@91061	NA|NA|NA		
AHPHCOMF_01899	264199.stu0884	0.0	1812.7	Bacilli	res_1		3.1.21.5	ko:K01156					ko00000,ko01000,ko02048				Bacteria	1TRVK@1239,4HAVG@91061,COG3421@1,COG3421@2	NA|NA|NA	S	Type III restriction
AHPHCOMF_01900	264199.stu0885	0.0	1256.9	Bacilli	sthIM		2.1.1.72	ko:K07316					ko00000,ko01000,ko02048				Bacteria	1TR8A@1239,4HBP1@91061,COG2189@1,COG2189@2	NA|NA|NA	L	Adenine specific DNA methylase Mod
AHPHCOMF_01901	264199.stu0886	3.9e-303	1046.6	Bacilli	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.3.1.128,6.3.5.2	ko:K01951,ko:K03790	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002,ko03009			iJN746.PP_1032,iLJ478.TM1820,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833	Bacteria	1TPG8@1239,4HA7Q@91061,COG0518@1,COG0518@2,COG0519@1,COG0519@2	NA|NA|NA	F	Catalyzes the synthesis of GMP from XMP
AHPHCOMF_01902	322159.STER_0913	2e-126	458.4	Bacilli	gntR1			ko:K03710,ko:K11922					ko00000,ko03000				Bacteria	1UYBW@1239,4HDDG@91061,COG2188@1,COG2188@2	NA|NA|NA	K	transcriptional
AHPHCOMF_01903	264199.stu0888	1.1e-53	215.7	Bacilli	ylxM	GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772		ko:K09787					ko00000				Bacteria	1VEGP@1239,4HKK6@91061,COG2739@1,COG2739@2	NA|NA|NA	S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AHPHCOMF_01904	264199.stu0889	1.4e-273	948.3	Bacilli	ffh	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9			Bacteria	1TP06@1239,4H9T4@91061,COG0541@1,COG0541@2	NA|NA|NA	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AHPHCOMF_01905	264199.stu0890	3.1e-87	327.8	Bacilli	niaX	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K16788					ko00000,ko02000	2.A.88.5			Bacteria	1V4NF@1239,2A1RE@1,311D4@2,4HH6C@91061	NA|NA|NA		
AHPHCOMF_01906	264199.stu0891	1e-17	95.1	Bacilli	niaR			ko:K07105					ko00000				Bacteria	1V6EY@1239,4HGYB@91061,COG1827@1,COG1827@2	NA|NA|NA	S	small molecule binding protein (contains 3H domain)
AHPHCOMF_01907	264199.stu0891	2e-45	188.0	Bacilli	niaR			ko:K07105					ko00000				Bacteria	1V6EY@1239,4HGYB@91061,COG1827@1,COG1827@2	NA|NA|NA	S	small molecule binding protein (contains 3H domain)
AHPHCOMF_01908	264199.stu0892	1.6e-128	465.3	Bacilli													Bacteria	1V758@1239,4HIKZ@91061,COG1396@1,COG1396@2,COG2932@1,COG2932@2	NA|NA|NA	K	DNA-binding helix-turn-helix protein
AHPHCOMF_01909	264199.stu0893	1.1e-158	565.8	Bacilli	ylqF	GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840		ko:K14540					ko00000,ko03009				Bacteria	1TQGK@1239,4HA4D@91061,COG1161@1,COG1161@2	NA|NA|NA	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AHPHCOMF_01910	322159.STER_0920	2e-135	488.4	Bacilli	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030				ko00000,ko00001,ko01000,ko03032				Bacteria	1V1D6@1239,4HB7M@91061,COG0164@1,COG0164@2	NA|NA|NA	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AHPHCOMF_01911	322159.STER_0921	4.1e-167	594.0	Firmicutes													Bacteria	1TRQ7@1239,COG1940@1,COG1940@2	NA|NA|NA	GK	ROK family
AHPHCOMF_01912	264199.stu0896	3.2e-158	564.3	Bacilli	dprA	GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496		ko:K04096					ko00000				Bacteria	1TPP7@1239,4HGWM@91061,COG0758@1,COG0758@2	NA|NA|NA	LU	DNA protecting protein DprA
AHPHCOMF_01913	264199.stu0897	0.0	1319.7	Bacilli	topA		5.99.1.2	ko:K03168					ko00000,ko01000,ko03032,ko03400				Bacteria	1TPUS@1239,4HA6C@91061,COG0550@1,COG0550@2	NA|NA|NA	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AHPHCOMF_01914	322159.STER_0924	1.4e-150	538.9	Bacilli													Bacteria	1V2FW@1239,2DC01@1,2ZC51@2,4HG69@91061	NA|NA|NA	S	TraX protein
AHPHCOMF_01915	322159.STER_0925	2.2e-122	444.9	Firmicutes													Bacteria	1TQ0D@1239,COG0745@1,COG0745@2	NA|NA|NA	KT	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AHPHCOMF_01916	264199.stu0902	1.3e-252	878.6	Bacilli													Bacteria	1TS1G@1239,4HEWT@91061,COG0642@1,COG2205@2	NA|NA|NA	T	PhoQ Sensor
AHPHCOMF_01917	322159.STER_0927	6.6e-259	899.4	Bacilli	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094					ko00000,ko01000,ko03016,ko03036				Bacteria	1TP67@1239,4HB27@91061,COG1206@1,COG1206@2	NA|NA|NA	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AHPHCOMF_01918	264199.stu0905	4.2e-152	543.9	Bacilli	XK27_05470												Bacteria	1TPDQ@1239,4HADW@91061,COG0620@1,COG0620@2	NA|NA|NA	E	Methionine synthase
AHPHCOMF_01919	264199.stu0906	1.7e-75	288.5	Firmicutes	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131				Bacteria	1V44G@1239,COG0105@1,COG0105@2	NA|NA|NA	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
AHPHCOMF_01920	322159.STER_0930	2.7e-48	197.6	Bacteria	pspE			ko:K03972					ko00000				Bacteria	COG0607@1,COG0607@2	NA|NA|NA	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AHPHCOMF_01921	264199.stu0909	6e-43	179.9	Bacilli													Bacteria	1TRQC@1239,4HD7P@91061,COG1028@1,COG1028@2	NA|NA|NA	IQ	Acetoin reductase
AHPHCOMF_01922	1095726.HMPREF1116_1390	3.9e-19	99.8	Bacilli													Bacteria	1TRQC@1239,4HD7P@91061,COG1028@1,COG1028@2	NA|NA|NA	IQ	Acetoin reductase
AHPHCOMF_01923	264199.stu0911	0.0	1176.8	Bacilli	lepA			ko:K03596	ko05134,map05134				ko00000,ko00001				Bacteria	1TP0G@1239,4HASA@91061,COG0481@1,COG0481@2	NA|NA|NA	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
AHPHCOMF_01924	322159.STER_0934	1.8e-156	558.5	Bacilli	Z012_04635												Bacteria	1UZI0@1239,4HC2C@91061,COG1396@1,COG1396@2	NA|NA|NA	K	Transcriptional activator, Rgg GadR MutR family
AHPHCOMF_01927	264199.stu0920	1.1e-212	745.7	Firmicutes	pqqE												Bacteria	1TR52@1239,COG0535@1,COG0535@2	NA|NA|NA	C	radical SAM domain protein
AHPHCOMF_01928	264199.stu0921	3.9e-136	490.7	Bacteria	speB		3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000				Bacteria	COG0010@1,COG0010@2	NA|NA|NA	E	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
AHPHCOMF_01929	1121864.OMO_01537	6.6e-61	241.5	Bacteria				ko:K08218	ko01501,map01501	M00628			ko00000,ko00001,ko00002,ko02000	2.A.1.25			Bacteria	COG0477@1,COG2814@2	NA|NA|NA	EGP	Major facilitator Superfamily
AHPHCOMF_01930	322159.STER_0940	0.0	1105.1	Bacilli	alsS		2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQE8@1239,4HAV1@91061,COG0028@1,COG0028@2	NA|NA|NA	EH	Belongs to the TPP enzyme family
AHPHCOMF_01931	322159.STER_0941	3e-133	481.1	Bacilli	budA	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0047605	4.1.1.5	ko:K01575	ko00650,ko00660,map00650,map00660		R02948	RC00812	ko00000,ko00001,ko01000				Bacteria	1V4AH@1239,4HJ98@91061,COG3527@1,COG3527@2	NA|NA|NA	H	Belongs to the alpha-acetolactate decarboxylase family
AHPHCOMF_01932	1046629.Ssal_00336	4.3e-13	79.3	Bacteria													Bacteria	COG3464@1,COG3464@2	NA|NA|NA		
AHPHCOMF_01933	322159.STER_1055	8e-160	569.7	Firmicutes				ko:K07485					ko00000				Bacteria	1TQ93@1239,COG3464@1,COG3464@2	NA|NA|NA	L	Transposase
AHPHCOMF_01934	1316408.HSISM1_519	2.8e-57	228.0	Bacilli				ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	1TPHU@1239,4HA2C@91061,COG0577@1,COG0577@2	NA|NA|NA	V	ABC transporter (Permease
# 1741 queries scanned
# Total time (seconds): 5.02758383751
# Rate: 346.29 q/s