# emapper version: emapper-2.0.1b-2-g816e190 emapper DB: 2.0
# command: ./emapper.py  -i Streptococcus_thermophilus/1.contigAnn/FFN/A00000051.ffn --translate --temp_dir Streptococcus_thermophilus/4.eggNOG_mapper --output_dir Streptococcus_thermophilus/4.eggNOG_mapper --output A00000051 --cpu 36 --keep_mapping_files -m diamond
# time: Wed Jul 13 07:57:21 2022
#query_name	seed_eggNOG_ortholog	seed_ortholog_evalue	seed_ortholog_score	best_tax_level	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	taxonomic scope	eggNOG OGs	best eggNOG OG	COG Functional cat.	eggNOG free text desc.
NHHNPPIF_00001	1316408.HSISM1_519	8.2e-118	429.9	Bacilli				ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	1TPHU@1239,4HA2C@91061,COG0577@1,COG0577@2	NA|NA|NA	V	ABC transporter (Permease
NHHNPPIF_00002	904306.HMPREF9192_1786	3.4e-113	414.5	Bacilli													Bacteria	1TRQB@1239,4HAY3@91061,COG1028@1,COG1028@2	NA|NA|NA	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family
NHHNPPIF_00003	888746.HMPREF9180_1259	1.6e-10	71.6	Bacilli													Bacteria	1W4NX@1239,2DD3F@1,2ZGBB@2,4I0KR@91061	NA|NA|NA		
NHHNPPIF_00004	322159.STER_0946	1.2e-97	362.5	Bacilli													Bacteria	1TSUJ@1239,4IPZN@91061,COG1309@1,COG1309@2	NA|NA|NA	K	Transcriptional regulator, TetR family
NHHNPPIF_00005	264199.stu0932	1.3e-157	562.4	Bacilli	czcD			ko:K16264					ko00000,ko02000	2.A.4.1			Bacteria	1TR92@1239,4HBCQ@91061,COG1230@1,COG1230@2	NA|NA|NA	P	cation diffusion facilitator family transporter
NHHNPPIF_00006	322159.STER_0948	2.3e-209	734.6	Bacilli	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPKF@1239,4HAYG@91061,COG0276@1,COG0276@2	NA|NA|NA	H	Catalyzes the ferrous insertion into protoporphyrin IX
NHHNPPIF_00007	322159.STER_0949	3.1e-195	687.6	Bacilli	adhB		1.1.1.1,1.1.1.14	ko:K00001,ko:K00008	ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	M00014	R00623,R00754,R00875,R01896,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00085,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPIW@1239,4HB2G@91061,COG1063@1,COG1063@2	NA|NA|NA	E	Dehydrogenase
NHHNPPIF_00008	1046629.Ssal_01058	2.3e-07	60.1	Bacilli				ko:K06889					ko00000				Bacteria	1TPW7@1239,4HEFQ@91061,COG1073@1,COG1073@2	NA|NA|NA	S	Hydrolases of the alpha beta superfamily
NHHNPPIF_00009	264199.stu0937	7.9e-17	92.0	Bacteria													Bacteria	COG4814@1,COG4814@2	NA|NA|NA	S	Alpha/beta hydrolase of unknown function (DUF915)
NHHNPPIF_00010	264199.stu0938	1.2e-79	302.4	Bacteria													Bacteria	COG4814@1,COG4814@2	NA|NA|NA	S	Alpha/beta hydrolase of unknown function (DUF915)
NHHNPPIF_00013	264199.stu0941	2.6e-143	514.6	Bacilli			2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100		R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000				Bacteria	1TQ71@1239,4HUI7@91061,COG2820@1,COG2820@2	NA|NA|NA	F	Phosphorylase superfamily
NHHNPPIF_00014	322159.STER_0956	8.3e-119	433.0	Bacilli	gph		3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130		R01334	RC00017	ko00000,ko00001,ko01000				Bacteria	1TPPZ@1239,4IPIP@91061,COG0546@1,COG0546@2	NA|NA|NA	S	HAD hydrolase, family IA, variant 1
NHHNPPIF_00015	1046629.Ssal_01070	6.1e-18	96.7	Bacilli	yclQ			ko:K02016	ko02010,map02010	M00240			ko00000,ko00001,ko00002,ko02000	3.A.1.14			Bacteria	1UXCZ@1239,4HAMP@91061,COG4607@1,COG4607@2	NA|NA|NA	P	ABC-type enterochelin transport system, periplasmic component
NHHNPPIF_00016	264199.stu0946	2.3e-19	102.1	Bacteria													Bacteria	COG0534@1,COG0534@2	NA|NA|NA	V	drug transmembrane transporter activity
NHHNPPIF_00017	904306.HMPREF9192_1770	3.9e-15	86.7	Bacilli	dinF												Bacteria	1TNZN@1239,4HANM@91061,COG0534@1,COG0534@2	NA|NA|NA	V	Mate efflux family protein
NHHNPPIF_00019	264199.stu0950	3e-309	1067.0	Bacilli	FbpA			ko:K12341	ko03070,map03070				ko00000,ko00001,ko02044	1.B.40.1.1			Bacteria	1TQ8A@1239,4H9UF@91061,COG1293@1,COG1293@2	NA|NA|NA	K	RNA-binding protein homologous to eukaryotic snRNP
NHHNPPIF_00021	904306.HMPREF9192_1767	6.1e-81	307.0	Bacilli													Bacteria	1V7WE@1239,2B4EH@1,31X62@2,4HJ8G@91061	NA|NA|NA	S	TraX protein
NHHNPPIF_00022	264199.stu0953	6.5e-96	356.7	Bacilli	thiJ		2.7.11.1,3.5.1.124	ko:K03152,ko:K05520,ko:K12132					ko00000,ko01000,ko01001,ko01002				Bacteria	1V3WB@1239,4HM36@91061,COG0693@1,COG0693@2	NA|NA|NA	S	DJ-1 family
NHHNPPIF_00023	264199.stu0954	4.8e-148	530.4	Bacilli	pyrK	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042602,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0052875,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576		ko:K02823	ko00240,ko01100,map00240,map01100				ko00000,ko00001			iYO844.BSU15530	Bacteria	1TQ5D@1239,4HAU4@91061,COG0543@1,COG0543@2	NA|NA|NA	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NHHNPPIF_00024	1046629.Ssal_01079	1.9e-175	621.7	Bacilli	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.98.1	ko:K00226,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01867,R01869	RC00051	ko00000,ko00001,ko00002,ko01000			iYO844.BSU15540	Bacteria	1TPFV@1239,4HA5H@91061,COG0167@1,COG0167@2	NA|NA|NA	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NHHNPPIF_00025	264199.stu0967	9.1e-127	459.5	Bacilli	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000			iECO103_1326.ECO103_1444,iECSF_1327.ECSF_1264,iSFV_1184.SFV_1294,iSF_1195.SF1285,iSFxv_1172.SFxv_1457,iS_1188.S1368,ic_1306.c1750	Bacteria	1TPPH@1239,4HAJ2@91061,COG0284@1,COG0284@2	NA|NA|NA	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NHHNPPIF_00026	322159.STER_0981	7.5e-112	409.8	Bacilli	pyrE		2.4.2.10,4.1.1.23	ko:K00762,ko:K01591,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000			iYO844.BSU15560	Bacteria	1V1BZ@1239,4HFV7@91061,COG0461@1,COG0461@2	NA|NA|NA	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NHHNPPIF_00027	435842.HMPREF0848_00691	1.2e-63	249.2	Bacilli	nylA		3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120		R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000				Bacteria	1TPGJ@1239,4HBE7@91061,COG0154@1,COG0154@2	NA|NA|NA	J	Belongs to the amidase family
NHHNPPIF_00028	322159.STER_0984	9.7e-264	915.6	Bacilli	dtpT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K03305					ko00000	2.A.17			Bacteria	1TP81@1239,4HAF2@91061,COG3104@1,COG3104@2	NA|NA|NA	E	transporter
NHHNPPIF_00029	264199.stu0973	5.6e-104	384.0	Bacilli	nylA		3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120		R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000				Bacteria	1TPGJ@1239,4HBE7@91061,COG0154@1,COG0154@2	NA|NA|NA	J	Belongs to the amidase family
NHHNPPIF_00030	264199.stu0974	2.4e-61	241.5	Bacilli	yckB			ko:K02030,ko:K02424	ko02010,map02010	M00234,M00236			ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3,3.A.1.3.10,3.A.1.3.14			Bacteria	1UHHG@1239,4H9NX@91061,COG0834@1,COG0834@2	NA|NA|NA	ET	Belongs to the bacterial solute-binding protein 3 family
NHHNPPIF_00031	264199.stu0975	2.9e-58	231.1	Bacilli	artJ_1			ko:K02030,ko:K09996,ko:K09997	ko02010,map02010	M00229,M00236			ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.3			Bacteria	1UHHG@1239,4H9NX@91061,COG0834@1,COG0834@2	NA|NA|NA	ET	Belongs to the bacterial solute-binding protein 3 family
NHHNPPIF_00032	699248.SRA_05851	5.5e-53	214.2	Bacilli	yecS	GO:0000099,GO:0000101,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006791,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015184,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015811,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:0098656,GO:1901682,GO:1902475,GO:1903825,GO:1905039		ko:K10009	ko02010,map02010	M00234			ko00000,ko00001,ko00002,ko02000	3.A.1.3.10,3.A.1.3.14		iJN746.PP_0226	Bacteria	1TQ43@1239,4HCZV@91061,COG0765@1,COG0765@2	NA|NA|NA	P	ABC transporter (Permease
NHHNPPIF_00034	1046629.Ssal_01083	2.6e-23	114.4	Bacilli	sasH		3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110		R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000				Bacteria	1TPV2@1239,4H9VJ@91061,COG0737@1,COG0737@2	NA|NA|NA	F	Belongs to the 5'-nucleotidase family
NHHNPPIF_00035	264199.stu0981	2.5e-63	248.1	Bacteria	yfiF3												Bacteria	COG4977@1,COG4977@2	NA|NA|NA	K	sequence-specific DNA binding
NHHNPPIF_00036	1046629.Ssal_01085	5.5e-24	116.3	Bacilli	bglC												Bacteria	1UZG6@1239,4HCQS@91061,COG2207@1,COG2207@2	NA|NA|NA	K	Transcriptional regulator
NHHNPPIF_00037	322159.STER_0992	8.6e-246	855.9	Bacilli	mnmE	GO:0003674,GO:0005488,GO:0005515,GO:0042802		ko:K03650			R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016				Bacteria	1TPJF@1239,4HA06@91061,COG0486@1,COG0486@2	NA|NA|NA	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NHHNPPIF_00038	322159.STER_0993	4e-240	837.0	Bacilli	agcS	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K03310					ko00000	2.A.25			Bacteria	1TNZP@1239,4H9SZ@91061,COG1115@1,COG1115@2	NA|NA|NA	E	(Alanine) symporter
NHHNPPIF_00039	322159.STER_0994	0.0	1385.5	Bacilli	pcrA		3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430				ko00000,ko00001,ko01000,ko03400				Bacteria	1TPSU@1239,4HB12@91061,COG0210@1,COG0210@2	NA|NA|NA	L	ATP-dependent DNA helicase
NHHNPPIF_00040	322159.STER_0995	2.3e-240	837.8	Bacilli	metY		2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100		R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000				Bacteria	1VYCY@1239,4H9X5@91061,COG2873@1,COG2873@2	NA|NA|NA	E	o-acetylhomoserine
NHHNPPIF_00041	904306.HMPREF9192_1752	3.2e-133	481.1	Bacilli													Bacteria	1TQTU@1239,4HEHK@91061,COG0561@1,COG0561@2	NA|NA|NA	S	haloacid dehalogenase-like hydrolase
NHHNPPIF_00042	264199.stu0990	3.8e-87	327.4	Bacilli	tpx	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009405,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0020012,GO:0030312,GO:0030682,GO:0032843,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K11065					ko00000,ko01000				Bacteria	1V474@1239,4HFMW@91061,COG2077@1,COG2077@2	NA|NA|NA	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NHHNPPIF_00043	264199.stu0991	1.1e-110	406.0	Bacilli	hsdS2		2.1.1.72	ko:K03427					ko00000,ko01000,ko02048				Bacteria	1VQES@1239,4HE4K@91061,COG0732@1,COG0732@2	NA|NA|NA	V	Type I restriction modification DNA specificity domain
NHHNPPIF_00044	435842.HMPREF0848_00681	5.7e-33	146.4	Bacteria	M1-755			ko:K09155					ko00000				Bacteria	COG2461@1,COG2461@2	NA|NA|NA	P	Hemerythrin HHE cation binding domain protein
NHHNPPIF_00045	264199.stu0993	2.4e-77	295.0	Bacilli	XK27_04775			ko:K09155					ko00000				Bacteria	1TRD5@1239,4HAAW@91061,COG2461@1,COG2461@2	NA|NA|NA	S	hemerythrin HHE cation binding domain
NHHNPPIF_00046	904306.HMPREF9192_1747	3.1e-69	268.1	Bacilli	XK27_04775			ko:K09155					ko00000				Bacteria	1TRD5@1239,4HAAW@91061,COG2461@1,COG2461@2	NA|NA|NA	S	hemerythrin HHE cation binding domain
NHHNPPIF_00047	904306.HMPREF9192_1747	4.4e-49	200.3	Bacilli	XK27_04775			ko:K09155					ko00000				Bacteria	1TRD5@1239,4HAAW@91061,COG2461@1,COG2461@2	NA|NA|NA	S	hemerythrin HHE cation binding domain
NHHNPPIF_00048	264199.stu0995	8.4e-151	539.7	Bacilli	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177,ko:K03483					ko00000,ko01000,ko03000,ko03016			iSB619.SA_RS06305	Bacteria	1TP9Y@1239,4HA9X@91061,COG0130@1,COG0130@2	NA|NA|NA	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NHHNPPIF_00049	264199.stu0996	5.5e-172	610.1	Bacilli	ribF		2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000			iSB619.SA_RS06310	Bacteria	1TPKS@1239,4H9KE@91061,COG0196@1,COG0196@2	NA|NA|NA	H	Belongs to the ribF family
NHHNPPIF_00050	264199.stu0997	5.7e-68	263.5	Bacilli	spxA		1.20.4.1	ko:K00537,ko:K16509					ko00000,ko01000				Bacteria	1V3QC@1239,4HH0I@91061,COG1393@1,COG1393@2	NA|NA|NA	K	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NHHNPPIF_00051	264199.stu0998	6.7e-44	183.0	Bacilli	yktA			ko:K16509					ko00000				Bacteria	1VEK8@1239,4HNKR@91061,COG4476@1,COG4476@2	NA|NA|NA	S	Belongs to the UPF0223 family
NHHNPPIF_00052	322159.STER_1004	4.2e-141	507.3	Bacilli	suhB		3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000				Bacteria	1TR4E@1239,4HB92@91061,COG0483@1,COG0483@2	NA|NA|NA	G	Belongs to the inositol monophosphatase superfamily
NHHNPPIF_00053	322159.STER_1005	3e-256	890.6	Bacilli	rsmF	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176,2.1.1.178	ko:K03500,ko:K11392					ko00000,ko01000,ko03009				Bacteria	1TPGQ@1239,4HCHQ@91061,COG0144@1,COG0144@2,COG3270@1,COG3270@2	NA|NA|NA	J	NOL1 NOP2 sun family protein
NHHNPPIF_00054	322159.STER_1006	1.4e-156	558.9	Bacilli	pstS	GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234		ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222			ko00000,ko00001,ko00002,ko02000	3.A.1.7			Bacteria	1TQ5X@1239,4HBEB@91061,COG0226@1,COG0226@2	NA|NA|NA	P	phosphate
NHHNPPIF_00055	264199.stu1002	2.5e-156	558.1	Bacilli	pstC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K02037	ko02010,map02010	M00222			ko00000,ko00001,ko00002,ko02000	3.A.1.7			Bacteria	1TSPP@1239,4HC9H@91061,COG0573@1,COG0573@2	NA|NA|NA	P	probably responsible for the translocation of the substrate across the membrane
NHHNPPIF_00056	322159.STER_1008	1.5e-155	555.4	Bacilli	pstA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K02038	ko02010,map02010	M00222			ko00000,ko00001,ko00002,ko02000	3.A.1.7			Bacteria	1TP74@1239,4HAKF@91061,COG0581@1,COG0581@2	NA|NA|NA	P	phosphate transport system permease
NHHNPPIF_00057	322159.STER_1009	1e-150	539.3	Bacilli	pstB		3.6.3.27	ko:K02036	ko02010,map02010	M00222			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7		iLJ478.TM1261	Bacteria	1TP1M@1239,4HAB1@91061,COG1117@1,COG1117@2	NA|NA|NA	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHHNPPIF_00058	322159.STER_1010	2.3e-139	501.5	Bacilli	pstB		3.6.3.27	ko:K02036	ko02010,map02010	M00222			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7		iLJ478.TM1261	Bacteria	1TP1M@1239,4HAB1@91061,COG1117@1,COG1117@2	NA|NA|NA	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHHNPPIF_00059	322159.STER_1011	1.9e-113	415.2	Bacilli	phoU			ko:K02039					ko00000				Bacteria	1URN3@1239,4HEU9@91061,COG0704@1,COG0704@2	NA|NA|NA	P	Plays a role in the regulation of phosphate uptake
NHHNPPIF_00060	264199.stu1007	0.0	1678.7	Bacilli	pepN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100		R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002				Bacteria	1TR43@1239,4HA20@91061,COG0308@1,COG0308@2	NA|NA|NA	E	aminopeptidase
NHHNPPIF_00061	322159.STER_1013	1e-193	682.6	Bacilli	xerS	GO:0000150,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360											Bacteria	1URNQ@1239,4HEPI@91061,COG4974@1,COG4974@2	NA|NA|NA	D	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
NHHNPPIF_00062	322159.STER_1014	4.2e-186	657.1	Bacilli	lplA		6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100		R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000				Bacteria	1TQ5U@1239,4H9P6@91061,COG0095@1,COG0095@2	NA|NA|NA	H	Lipoate-protein ligase
NHHNPPIF_00065	888816.HMPREF9389_1786	3.7e-09	68.2	Streptococcus sanguinis													Bacteria	1UA7P@1239,1WRVC@1305,2AQRJ@1,31FZC@2,4IKIV@91061	NA|NA|NA		
NHHNPPIF_00066	322159.STER_1016	0.0	1497.3	Bacilli	glgP		2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931		R02111		ko00000,ko00001,ko01000		GT35		Bacteria	1TQAJ@1239,4H9XI@91061,COG0058@1,COG0058@2	NA|NA|NA	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NHHNPPIF_00067	264199.stu1013	1.1e-302	1045.0	Bacilli	malQ		2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100		R05196	RC00049	ko00000,ko00001,ko01000		GH77		Bacteria	1W5VQ@1239,4HCHB@91061,COG1640@1,COG1640@2	NA|NA|NA	G	4-alpha-glucanotransferase
NHHNPPIF_00068	264199.stu1014	1.2e-62	245.7	Bacilli	malR			ko:K02529					ko00000,ko03000				Bacteria	1TPZM@1239,4H9ZT@91061,COG1609@1,COG1609@2	NA|NA|NA	K	Transcriptional regulator
NHHNPPIF_00069	264199.stu1014	3.7e-46	190.7	Bacilli	malR			ko:K02529					ko00000,ko03000				Bacteria	1TPZM@1239,4H9ZT@91061,COG1609@1,COG1609@2	NA|NA|NA	K	Transcriptional regulator
NHHNPPIF_00070	1046629.Ssal_01117	4.2e-17	93.2	Bacilli	malX			ko:K02027,ko:K15770	ko02010,map02010	M00207,M00491			ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2			Bacteria	1TPU9@1239,4H9TU@91061,COG2182@1,COG2182@2	NA|NA|NA	G	ABC transporter
NHHNPPIF_00071	1046629.Ssal_01117	9.1e-168	596.3	Bacilli	malX			ko:K02027,ko:K15770	ko02010,map02010	M00207,M00491			ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2			Bacteria	1TPU9@1239,4H9TU@91061,COG2182@1,COG2182@2	NA|NA|NA	G	ABC transporter
NHHNPPIF_00072	904306.HMPREF9192_1726	1.1e-202	712.6	Bacilli	malF			ko:K02025,ko:K02026,ko:K15771	ko02010,map02010	M00207,M00491			ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2			Bacteria	1TR2A@1239,4HB8H@91061,COG1175@1,COG1175@2	NA|NA|NA	P	ABC transporter (Permease
NHHNPPIF_00073	264199.stu0036	4.2e-10	69.3	Bacteria				ko:K07483					ko00000				Bacteria	COG2963@1,COG2963@2	NA|NA|NA	L	transposase activity
NHHNPPIF_00074	435842.HMPREF0848_01320	3.6e-39	167.2	Bacilli				ko:K07483					ko00000				Bacteria	1VDX9@1239,4HRT2@91061,COG2963@1,COG2963@2	NA|NA|NA	L	Transposase
NHHNPPIF_00075	264199.stu0770	0.0	1635.2	Bacilli			3.6.3.8	ko:K01537,ko:K12955					ko00000,ko01000	3.A.3.2,3.A.3.24			Bacteria	1TPF5@1239,4H9S5@91061,COG0474@1,COG0474@2	NA|NA|NA	P	cation transport ATPase
NHHNPPIF_00076	264199.stu0771	0.0	1142.9	Bacilli	pabB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.6.1.85,4.1.3.27,4.1.3.38	ko:K01665,ko:K02619,ko:K03342,ko:K13503,ko:K13950	ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00400,map00790,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01716,R05553	RC00010,RC01418,RC01843,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	1TQAP@1239,4HBKC@91061,COG0115@1,COG0115@2,COG0147@1,COG0147@2	NA|NA|NA	EH	component I
NHHNPPIF_00078	264199.stu0785	0.0	1490.3	Bacilli	metE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0030312,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0040007,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0071944,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000			iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131	Bacteria	1TP2H@1239,4H9QC@91061,COG0620@1,COG0620@2	NA|NA|NA	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NHHNPPIF_00079	264199.stu0786	1.1e-164	585.9	Bacilli	metF	GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.5.1.20	ko:K00297,ko:K21010	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,ko02025,map00670,map00720,map01100,map01120,map01200,map01523,map02025	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000			iPC815.YPO0117,iSBO_1134.SBO_3961	Bacteria	1TQFE@1239,4HGHI@91061,COG0685@1,COG0685@2	NA|NA|NA	C	reductase
NHHNPPIF_00080	322159.STER_0833	0.0	1114.8	Bacilli	pgm	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP2N@1239,4HADU@91061,COG1109@1,COG1109@2	NA|NA|NA	G	Phosphoglucomutase
NHHNPPIF_00081	264199.stu0788	1.1e-93	349.4	Bacilli	panT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944											Bacteria	1V2M1@1239,4HFPD@91061,COG4684@1,COG4684@2	NA|NA|NA	S	ECF transporter, substrate-specific component
NHHNPPIF_00082	264199.stu0789	1.4e-90	339.0	Bacilli	coaBC		4.1.1.36,6.3.2.5	ko:K01598,ko:K13038,ko:K21977	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPP3@1239,4HAK8@91061,COG0452@1,COG0452@2	NA|NA|NA	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NHHNPPIF_00083	264199.stu0790	2.8e-120	438.0	Bacilli	coaB		4.1.1.36,6.3.2.5	ko:K01598,ko:K13038,ko:K21977	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000				Bacteria	1V7YG@1239,4HMIF@91061,COG0452@1,COG0452@2	NA|NA|NA	H	Phosphopantothenate-cysteine ligase
NHHNPPIF_00084	322159.STER_0837	0.0	1093.2	Bacilli	fhs	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP6N@1239,4HA2X@91061,COG2759@1,COG2759@2	NA|NA|NA	F	Belongs to the formate--tetrahydrofolate ligase family
NHHNPPIF_00085	904306.HMPREF9192_1233	1.2e-118	432.6	Bacilli													Bacteria	1V295@1239,4HG3X@91061,COG0745@1,COG0745@2	NA|NA|NA	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHHNPPIF_00086	904306.HMPREF9192_1234	1e-29	135.6	Bacilli													Bacteria	1UHNC@1239,4IS4A@91061,COG0642@1,COG2205@2	NA|NA|NA	T	PhoQ Sensor
NHHNPPIF_00087	904306.HMPREF9192_1234	4.1e-43	180.6	Bacilli													Bacteria	1UHNC@1239,4IS4A@91061,COG0642@1,COG2205@2	NA|NA|NA	T	PhoQ Sensor
NHHNPPIF_00088	264199.stu0795	1.7e-120	438.7	Bacilli													Bacteria	1UHNC@1239,4IS4A@91061,COG0642@1,COG2205@2	NA|NA|NA	T	PhoQ Sensor
NHHNPPIF_00089	264199.stu0797	5.1e-122	443.7	Bacilli				ko:K07483					ko00000				Bacteria	1V2T5@1239,4HFZ1@91061,COG2963@1,COG2963@2	NA|NA|NA	L	Transposase
NHHNPPIF_00090	264199.stu0796	1.2e-165	589.0	Firmicutes													Bacteria	1TQEG@1239,COG2801@1,COG2801@2	NA|NA|NA	L	integrase core domain
NHHNPPIF_00091	264199.stu0798	1.3e-29	135.2	Bacteria	rpsT	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02968	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	COG0268@1,COG0268@2	NA|NA|NA	J	rRNA binding
NHHNPPIF_00092	264199.stu0799	5.5e-172	610.1	Bacilli	coaA	GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.33	ko:K00867	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000			iECDH1ME8569_1439.ECDH1ME8569_3838,iECH74115_1262.ECH74115_5439,iECSE_1348.ECSE_4265,iECSF_1327.ECSF_3833,iECSP_1301.ECSP_5045,iECW_1372.ECW_m4332,iEcDH1_1363.EcDH1_4016,iEcolC_1368.EcolC_4046,iPC815.YPO3758,iSFV_1184.SFV_4047,iSFxv_1172.SFxv_4418,iWFL_1372.ECW_m4332,iZ_1308.Z5545	Bacteria	1TPHJ@1239,4HA4K@91061,COG1072@1,COG1072@2	NA|NA|NA	F	Pantothenic acid kinase
NHHNPPIF_00093	322159.STER_0852	3.7e-105	387.5	Bacilli	rsmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	2.1.1.172	ko:K00564			R07234	RC00003	ko00000,ko01000,ko03009				Bacteria	1V3JX@1239,4IR00@91061,COG2813@1,COG2813@2	NA|NA|NA	J	Methyltransferase small domain protein
NHHNPPIF_00094	1046629.Ssal_00947	2.3e-26	124.4	Bacilli	pdp	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016757,GO:0016758,GO:0044424,GO:0044444,GO:0044464	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219		R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000				Bacteria	1TPCH@1239,4H9NP@91061,COG0213@1,COG0213@2	NA|NA|NA	F	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
NHHNPPIF_00095	264199.stu0802	3e-23	113.6	Bacteria	pdp	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016757,GO:0016758,GO:0044424,GO:0044444,GO:0044464	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219		R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000				Bacteria	COG0213@1,COG0213@2	NA|NA|NA	F	phosphorylase activity
NHHNPPIF_00096	435842.HMPREF0848_00806	6.1e-94	350.5	Bacilli	pdp	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016757,GO:0016758,GO:0044424,GO:0044444,GO:0044464	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219		R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000				Bacteria	1TPCH@1239,4H9NP@91061,COG0213@1,COG0213@2	NA|NA|NA	F	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
NHHNPPIF_00097	264199.stu0804	1.1e-10	71.6	Bacteria	pdp	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016757,GO:0016758,GO:0044424,GO:0044444,GO:0044464	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219		R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000				Bacteria	COG0213@1,COG0213@2	NA|NA|NA	F	phosphorylase activity
NHHNPPIF_00098	1046629.Ssal_00948	2.9e-30	137.5	Bacilli	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4,5.4.2.8	ko:K01619,ko:K01840	ko00030,ko00051,ko00520,ko01100,ko01110,ko01130,map00030,map00051,map00520,map01100,map01110,map01130	M00114	R01066,R01818	RC00408,RC00436,RC00437	ko00000,ko00001,ko00002,ko01000			iSB619.SA_RS00835	Bacteria	1TPAJ@1239,4HAAJ@91061,COG0274@1,COG0274@2	NA|NA|NA	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NHHNPPIF_00099	264199.stu0806	4e-63	247.3	Bacilli	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4,5.4.2.8	ko:K01619,ko:K01840	ko00030,ko00051,ko00520,ko01100,ko01110,ko01130,map00030,map00051,map00520,map01100,map01110,map01130	M00114	R01066,R01818	RC00408,RC00436,RC00437	ko00000,ko00001,ko00002,ko01000			iSB619.SA_RS00835	Bacteria	1TPAJ@1239,4HAAJ@91061,COG0274@1,COG0274@2	NA|NA|NA	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NHHNPPIF_00100	264199.stu0807	4.7e-57	226.9	Bacilli	cdd		2.4.2.2,3.5.4.5	ko:K00756,ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100		R01570,R01876,R01878,R02296,R02484,R02485,R08221	RC00063,RC00074,RC00514	ko00000,ko00001,ko01000			iSB619.SA_RS07895	Bacteria	1V6IP@1239,4HIJ3@91061,COG0295@1,COG0295@2	NA|NA|NA	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NHHNPPIF_00101	322159.STER_0856	1.6e-191	675.2	Bacilli	tcsA			ko:K02058,ko:K07335		M00221			ko00000,ko00002,ko02000	3.A.1.2			Bacteria	1TPEU@1239,4HANH@91061,COG1744@1,COG1744@2	NA|NA|NA	S	ABC-type transport system, periplasmic component surface lipoprotein
NHHNPPIF_00102	322159.STER_0857	6.4e-282	976.1	Bacilli	xylG		3.6.3.17	ko:K02056,ko:K06400		M00221			ko00000,ko00002,ko01000,ko02000	3.A.1.2			Bacteria	1UYQA@1239,4HVSH@91061,COG3845@1,COG3845@2	NA|NA|NA	S	ABC transporter, ATP-binding protein
NHHNPPIF_00103	322159.STER_0858	4.7e-191	673.7	Bacilli	yufP	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944		ko:K02057		M00221			ko00000,ko00002,ko02000	3.A.1.2			Bacteria	1TP1F@1239,4H9VE@91061,COG4603@1,COG4603@2	NA|NA|NA	S	Belongs to the binding-protein-dependent transport system permease family
NHHNPPIF_00104	264199.stu0811	1e-168	599.4	Bacilli	yufQ			ko:K02057		M00221			ko00000,ko00002,ko02000	3.A.1.2			Bacteria	1TP8Y@1239,4HAX4@91061,COG1079@1,COG1079@2	NA|NA|NA	S	Belongs to the binding-protein-dependent transport system permease family
NHHNPPIF_00105	264199.stu0812	2e-120	438.3	Bacilli	ycbL	GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615	3.1.2.6	ko:K01069	ko00620,map00620		R01736	RC00004,RC00137	ko00000,ko00001,ko01000				Bacteria	1V6FA@1239,4HHRQ@91061,COG0491@1,COG0491@2	NA|NA|NA	S	COG0491 Zn-dependent hydrolases, including glyoxylases
NHHNPPIF_00106	904306.HMPREF9192_1246	0.0	1502.3	Bacilli	dinG	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7,3.6.4.12	ko:K02342,ko:K03722	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1TQHQ@1239,4HB2Y@91061,COG1199@1,COG1199@2,COG2176@1,COG2176@2	NA|NA|NA	L	helicase involved in DNA repair and perhaps also replication
NHHNPPIF_00107	322159.STER_0862	3.1e-81	307.8	Bacilli	ypmB												Bacteria	1VA2H@1239,4HNMM@91061,COG5353@1,COG5353@2	NA|NA|NA	S	Protein conserved in bacteria
NHHNPPIF_00108	264199.stu0817	1.6e-216	758.4	Bacilli	aspB	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297	2.6.1.1,2.6.1.14	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230		R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052	RC00006,RC00025	ko00000,ko00001,ko01000,ko01007			iHN637.CLJU_RS06550	Bacteria	1TP0J@1239,4HA13@91061,COG0436@1,COG0436@2	NA|NA|NA	E	Aminotransferase
NHHNPPIF_00109	264199.stu0818	4.2e-261	906.7	Bacilli	asnS	GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1TP38@1239,4H9YH@91061,COG0017@1,COG0017@2	NA|NA|NA	J	Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NHHNPPIF_00110	562983.HMPREF0433_01645	2.5e-15	88.6	Bacilli													Bacteria	1W2BC@1239,2DF7W@1,2ZQU2@2,4HZFK@91061	NA|NA|NA		
NHHNPPIF_00111	1046629.Ssal_00208	6.8e-54	216.5	Firmicutes													Bacteria	1TQ93@1239,COG3464@1,COG3464@2	NA|NA|NA	L	Transposase
NHHNPPIF_00112	264199.stu0822	5.4e-22	109.4	Bacteria													Bacteria	COG3464@1,COG3464@2	NA|NA|NA		
NHHNPPIF_00113	904306.HMPREF9192_0265	1.5e-12	77.8	Bacteria													Bacteria	COG3464@1,COG3464@2	NA|NA|NA		
NHHNPPIF_00116	888833.HMPREF9421_1411	6.3e-28	129.8	Bacilli				ko:K14194	ko05150,map05150				ko00000,ko00001				Bacteria	1TV1Y@1239,4HBHJ@91061,COG2373@1,COG2373@2,COG2931@1,COG2931@2	NA|NA|NA	Q	the current gene model (or a revised gene model) may contain a frame shift
NHHNPPIF_00117	888833.HMPREF9421_1411	3.7e-31	141.0	Bacilli				ko:K14194	ko05150,map05150				ko00000,ko00001				Bacteria	1TV1Y@1239,4HBHJ@91061,COG2373@1,COG2373@2,COG2931@1,COG2931@2	NA|NA|NA	Q	the current gene model (or a revised gene model) may contain a frame shift
NHHNPPIF_00118	246201.SM12261_0398	3.2e-17	94.0	Streptococcus mitis													Bacteria	1U4JG@1239,2AHCZ@1,2TPZV@28037,317PX@2,4IEB9@91061	NA|NA|NA	S	Domain of unknown function (DUF4649)
NHHNPPIF_00119	322159.STER_1155	5.4e-173	613.6	Bacilli	XK27_08835			ko:K01989,ko:K05832		M00247			ko00000,ko00002,ko02000				Bacteria	1TPB0@1239,4HE7G@91061,COG2984@1,COG2984@2	NA|NA|NA	S	ABC transporter substrate binding protein
NHHNPPIF_00120	264199.stu1189	2e-147	528.5	Bacilli	XK27_08840			ko:K01989,ko:K05832		M00247			ko00000,ko00002,ko02000				Bacteria	1TPDJ@1239,4HBMY@91061,COG4120@1,COG4120@2	NA|NA|NA	S	Belongs to the binding-protein-dependent transport system permease family
NHHNPPIF_00121	264199.stu1188	4.4e-135	487.3	Bacilli	XK27_08845			ko:K05833		M00247			ko00000,ko00002,ko02000				Bacteria	1TPAN@1239,4HCHC@91061,COG1101@1,COG1101@2	NA|NA|NA	S	abc transporter atp-binding protein
NHHNPPIF_00122	264199.stu1187	1.9e-308	1064.3	Bacilli	rnjB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360		ko:K12574	ko03018,map03018				ko00000,ko00001,ko01000,ko03019				Bacteria	1TQ9G@1239,4HAAP@91061,COG0595@1,COG0595@2	NA|NA|NA	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHHNPPIF_00123	264199.stu1186	1.1e-149	535.8	Bacilli	estA			ko:K03930					ko00000,ko01000		CE1		Bacteria	1TPA9@1239,4IPZQ@91061,COG0627@1,COG0627@2	NA|NA|NA	S	Putative esterase
NHHNPPIF_00124	264199.stu1185	3e-125	454.5	Bacilli	XK27_08875												Bacteria	1VW9X@1239,4HWF8@91061,COG5549@1,COG5549@2	NA|NA|NA	O	Zinc-dependent metalloprotease
NHHNPPIF_00125	1214166.ALLG01000018_gene972	3.3e-14	84.7	Streptococcus suis	XK27_08880												Bacteria	1U92D@1239,1WTJN@1307,29R1H@1,30C2M@2,4IJ2X@91061	NA|NA|NA		
NHHNPPIF_00126	435842.HMPREF0848_00535	1e-75	289.3	Bacilli	fld			ko:K03839					ko00000				Bacteria	1V7AG@1239,4HMJF@91061,COG0716@1,COG0716@2	NA|NA|NA	C	Flavodoxin
NHHNPPIF_00127	264199.stu1182	1.7e-282	978.0	Bacilli	clcA	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006821,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015672,GO:0015698,GO:0015706,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0031404,GO:0034220,GO:0042802,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071705,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600		ko:K03281					ko00000	2.A.49		iAF1260.b0155,iB21_1397.B21_00153,iBWG_1329.BWG_0148,iE2348C_1286.E2348C_0162,iEC042_1314.EC042_0155,iEC55989_1330.EC55989_0149,iECBD_1354.ECBD_3463,iECDH10B_1368.ECDH10B_0135,iECDH1ME8569_1439.ECDH1ME8569_0149,iECD_1391.ECD_00154,iECIAI1_1343.ECIAI1_0153,iECO103_1326.ECO103_0155,iECSE_1348.ECSE_0156,iECUMN_1333.ECUMN_0152,iECW_1372.ECW_m0152,iEKO11_1354.EKO11_3761,iETEC_1333.ETEC_0151,iEcDH1_1363.EcDH1_3447,iEcE24377_1341.EcE24377A_0160,iEcolC_1368.EcolC_3504,iJO1366.b0155,iSSON_1240.SSON_0167,iUMNK88_1353.UMNK88_159,iWFL_1372.ECW_m0152,iY75_1357.Y75_RS00790,iZ_1308.Z0166	Bacteria	1TPX0@1239,4HD2H@91061,COG0038@1,COG0038@2	NA|NA|NA	P	Chloride transporter, ClC family
NHHNPPIF_00128	264199.stu1181	8.7e-41	172.6	Bacteria	pheA	GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223	1.3.1.12,2.3.1.79,4.2.1.51,5.4.99.5	ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715,R01728	RC00125,RC00360,RC03116	ko00000,ko00001,ko00002,ko01000			iECNA114_1301.ECNA114_2667	Bacteria	COG1605@1,COG1605@2	NA|NA|NA	E	Chorismate mutase
NHHNPPIF_00129	322159.STER_1145	2.1e-219	768.1	Bacilli	XK27_05110												Bacteria	1TPX0@1239,4HBN3@91061,COG0038@1,COG0038@2	NA|NA|NA	P	chloride
NHHNPPIF_00130	264199.stu1179	8.5e-57	226.1	Bacilli	rplS	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02884	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V6FT@1239,4HIK3@91061,COG0335@1,COG0335@2	NA|NA|NA	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NHHNPPIF_00132	1046629.Ssal_01245	7.2e-20	102.4	Bacilli	WQ51_02665												Bacteria	1VPEZ@1239,2C91M@1,33E1E@2,4HRR2@91061	NA|NA|NA	S	Protein of unknown function (DUF3042)
NHHNPPIF_00133	264199.stu1177	3e-162	577.8	Bacilli	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110		R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016				Bacteria	1TPSC@1239,4HAVW@91061,COG0324@1,COG0324@2	NA|NA|NA	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NHHNPPIF_00134	322159.STER_1139	2.7e-88	331.3	Bacilli	ytsP		1.8.4.14	ko:K08968	ko00270,map00270		R02025	RC00639	ko00000,ko00001,ko01000				Bacteria	1V6GQ@1239,4HH7X@91061,COG1956@1,COG1956@2	NA|NA|NA	T	GAF domain-containing protein
NHHNPPIF_00135	322159.STER_1138	7.1e-295	1019.2	Bacilli	dnaX	GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	2.7.7.7	ko:K02341,ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1TPS9@1239,4HAUE@91061,COG2812@1,COG2812@2	NA|NA|NA	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHHNPPIF_00136	322159.STER_1136	4.2e-175	620.5	Bacilli	birA	GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837	6.3.4.15	ko:K03524,ko:K04096	ko00780,ko01100,map00780,map01100		R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000				Bacteria	1TQCU@1239,4HB60@91061,COG0340@1,COG0340@2,COG1654@1,COG1654@2	NA|NA|NA	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NHHNPPIF_00137	264199.stu1172	6e-203	713.4	Bacilli	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPCV@1239,4HB33@91061,COG0192@1,COG0192@2	NA|NA|NA	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NHHNPPIF_00138	322159.STER_1134	1.3e-36	160.2	Firmicutes			5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000				Bacteria	1UYUX@1239,COG0451@1,COG0451@2	NA|NA|NA	GM	Psort location CytoplasmicMembrane, score
NHHNPPIF_00139	322159.STER_1125	6e-196	689.9	Bacilli	galE		5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQ7N@1239,4H9U5@91061,COG1087@1,COG1087@2	NA|NA|NA	M	Belongs to the NAD(P)-dependent epimerase dehydratase family
NHHNPPIF_00141	322159.STER_1123	1.1e-231	808.9	Bacilli	murA		2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100		R00660	RC00350	ko00000,ko00001,ko01000,ko01011				Bacteria	1TPAU@1239,4H9KI@91061,COG0766@1,COG0766@2	NA|NA|NA	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHHNPPIF_00142	264199.stu1166	1.2e-25	121.7	Bacilli	epuA												Bacteria	1VMAH@1239,2EK0E@1,33DQZ@2,4HRG1@91061	NA|NA|NA	S	DNA-directed RNA polymerase subunit beta
NHHNPPIF_00143	264199.stu1165	7e-124	450.3	Bacilli	endA			ko:K15051					ko00000				Bacteria	1V4X2@1239,4HIF5@91061,COG2169@1,COG2169@2	NA|NA|NA	F	DNA RNA non-specific endonuclease
NHHNPPIF_00144	264199.stu1164	3.8e-111	407.5	Bacilli	tcyB_2			ko:K02029,ko:K02030,ko:K10040,ko:K17073,ko:K17074	ko02010,map02010	M00228,M00236,M00589			ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.20			Bacteria	1V14N@1239,4HJ9W@91061,COG0765@1,COG0765@2	NA|NA|NA	P	ABC transporter (permease)
NHHNPPIF_00145	322159.STER_1119	8e-115	419.9	Bacilli	gltJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K02029,ko:K10003,ko:K10040	ko02010,ko02020,map02010,map02020	M00228,M00230,M00236			ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.19,3.A.1.3.4		iJN746.PP_1070	Bacteria	1TQ5K@1239,4HE9C@91061,COG0765@1,COG0765@2	NA|NA|NA	P	ABC transporter (Permease
NHHNPPIF_00146	322159.STER_1118	9.2e-150	536.2	Bacilli	peb1A	GO:0005575,GO:0005623,GO:0009986,GO:0044464		ko:K10039	ko02010,map02010	M00228			ko00000,ko00001,ko00002,ko02000	3.A.1.3			Bacteria	1TT11@1239,4HAHV@91061,COG0834@1,COG0834@2	NA|NA|NA	ET	ABC-type amino acid transport signal transduction systems, periplasmic component domain
NHHNPPIF_00147	322159.STER_1117	2.1e-140	505.0	Bacilli	glnQ		3.6.3.21	ko:K02028,ko:K10041	ko02010,map02010	M00228,M00236			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3			Bacteria	1TNYD@1239,4H9WY@91061,COG1126@1,COG1126@2	NA|NA|NA	E	abc transporter atp-binding protein
NHHNPPIF_00148	322159.STER_1116	9.9e-129	466.1	Bacilli													Bacteria	1TPQG@1239,4HA8Q@91061,COG0745@1,COG0745@2	NA|NA|NA	KT	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHHNPPIF_00149	322159.STER_1115	5.8e-247	859.8	Bacilli	vicK		2.7.13.3	ko:K07652	ko02020,map02020	M00459			ko00000,ko00001,ko00002,ko01000,ko01001,ko02022				Bacteria	1TQ1H@1239,4HA52@91061,COG5002@1,COG5002@2	NA|NA|NA	T	Histidine kinase
NHHNPPIF_00150	322159.STER_1114	3.9e-153	547.4	Bacilli	vicX		3.1.26.11	ko:K00784	ko03013,map03013				ko00000,ko00001,ko01000,ko03016				Bacteria	1TQ8E@1239,4HAKD@91061,COG1235@1,COG1235@2	NA|NA|NA	S	Metal-dependent hydrolases of the beta-lactamase superfamily I
NHHNPPIF_00151	322159.STER_1113	4.2e-34	150.2	Bacteria				ko:K09790					ko00000				Bacteria	COG2832@1,COG2832@2	NA|NA|NA	F	Protein of unknown function (DUF454)
NHHNPPIF_00152	264199.stu1155	2.6e-230	804.3	Bacilli	murM		2.3.2.10,2.3.2.16	ko:K05363,ko:K11693,ko:K12554	ko00550,ko01100,map00550,map01100		R08776,R08779,R08780	RC00055,RC00064,RC00096	ko00000,ko00001,ko01000,ko01011				Bacteria	1TRZU@1239,4HC1Z@91061,COG2348@1,COG2348@2	NA|NA|NA	V	protein involved in methicillin resistance
NHHNPPIF_00153	264199.stu1154	9.2e-147	526.2	Bacilli	yidA	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050308											Bacteria	1TR16@1239,4HCZ6@91061,COG0561@1,COG0561@2	NA|NA|NA	S	hydrolases of the HAD superfamily
NHHNPPIF_00154	322159.STER_1109	2.4e-44	184.5	Bacteria	XK27_00115		2.3.1.128	ko:K03789					ko00000,ko01000,ko03009				Bacteria	COG0454@1,COG0456@2	NA|NA|NA	K	acetyltransferase
NHHNPPIF_00155	264199.stu1151	3.4e-67	260.8	Bacteria	ywiB												Bacteria	COG4506@1,COG4506@2	NA|NA|NA	S	Domain of unknown function (DUF1934)
NHHNPPIF_00156	322159.STER_1107	0.0	1628.2	Bacilli	pacL		3.6.3.8	ko:K01537					ko00000,ko01000	3.A.3.2			Bacteria	1TPF5@1239,4H9S5@91061,COG0474@1,COG0474@2	NA|NA|NA	P	cation transport ATPase
NHHNPPIF_00157	264199.stu1149	2e-135	488.4	Bacilli	nfrA		1.5.1.38,1.5.1.39	ko:K19285,ko:K19286	ko00740,ko01100,map00740,map01100		R05705,R05706	RC00126	ko00000,ko00001,ko01000				Bacteria	1UB8S@1239,4HEGP@91061,COG0778@1,COG0778@2	NA|NA|NA	C	nitroreductase
NHHNPPIF_00158	264199.stu1147	9.2e-183	646.0	Bacilli	yjjH												Bacteria	1V9B5@1239,4HJX0@91061,COG1409@1,COG1409@2	NA|NA|NA	S	Calcineurin-like phosphoesterase
NHHNPPIF_00159	322159.STER_1104	1.2e-202	712.2	Bacilli	queG	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979					ko00000,ko01000,ko03016				Bacteria	1TP6Q@1239,4HAEW@91061,COG1600@1,COG1600@2	NA|NA|NA	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NHHNPPIF_00160	264199.stu1146	1.8e-181	641.7	Bacilli	prfB	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576		ko:K02836					ko00000,ko03012				Bacteria	1TPSB@1239,4H9N2@91061,COG1186@1,COG1186@2	NA|NA|NA	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NHHNPPIF_00161	264199.stu1145	5.5e-124	450.3	Bacilli	ftsE	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363		ko:K09811,ko:K09812	ko02010,map02010	M00256			ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140			Bacteria	1TP58@1239,4H9Z2@91061,COG2884@1,COG2884@2	NA|NA|NA	D	cell division ATP-binding protein FtsE
NHHNPPIF_00162	322159.STER_1100	5.2e-162	577.0	Bacilli	ftsX	GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0031224,GO:0031226,GO:0032506,GO:0034097,GO:0040007,GO:0042173,GO:0042221,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0090529,GO:1902531		ko:K09811,ko:K09812	ko02010,map02010	M00256			ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140			Bacteria	1TPND@1239,4HA5A@91061,COG2177@1,COG2177@2	NA|NA|NA	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NHHNPPIF_00163	264199.stu1143	3.5e-93	347.4	Bacilli	mutX		3.6.1.55	ko:K03574					ko00000,ko01000,ko03400				Bacteria	1V66I@1239,4HHRE@91061,COG1051@1,COG1051@2	NA|NA|NA	F	NTP pyrophosphohydrolases including oxidative damage repair enzymes
NHHNPPIF_00164	264199.stu1142	8.1e-176	623.2	Bacilli	yubA												Bacteria	1TQ84@1239,4H9SR@91061,COG0628@1,COG0628@2	NA|NA|NA	S	permease
NHHNPPIF_00165	264199.stu1141	2.4e-223	781.2	Bacilli													Bacteria	1TT97@1239,4HAIA@91061,COG0457@1,COG0457@2	NA|NA|NA	G	COG0457 FOG TPR repeat
NHHNPPIF_00166	322159.STER_1096	6e-97	360.1	Bacilli	lepB		3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060				ko00000,ko00001,ko01000,ko01002				Bacteria	1V2BJ@1239,4HGCB@91061,COG0681@1,COG0681@2	NA|NA|NA	U	Belongs to the peptidase S26 family
NHHNPPIF_00167	264199.stu1139	6.5e-229	799.7	Bacilli	pepT	GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0034701,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045148,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.4	ko:K01258					ko00000,ko01000,ko01002				Bacteria	1TP3A@1239,4HAZE@91061,COG2195@1,COG2195@2	NA|NA|NA	E	Cleaves the N-terminal amino acid of tripeptides
NHHNPPIF_00168	264199.stu1138	1.2e-88	332.4	Bacilli	ebsA												Bacteria	1VQ5S@1239,2FI04@1,349T2@2,4HYC5@91061	NA|NA|NA	S	Family of unknown function (DUF5322)
NHHNPPIF_00169	264199.stu1136	2.8e-18	99.0	Bacilli													Bacteria	1VD79@1239,4HT02@91061,COG1388@1,COG1388@2	NA|NA|NA	M	LysM domain
NHHNPPIF_00170	322159.STER_1090	2.5e-121	441.4	Bacilli	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	1.17.7.4,2.5.1.19,2.7.1.26,2.7.4.25,2.7.7.2,6.3.2.1	ko:K00800,ko:K00945,ko:K02945,ko:K03527,ko:K03977,ko:K11753,ko:K13799	ko00240,ko00400,ko00410,ko00740,ko00770,ko00900,ko01100,ko01110,ko01130,ko01230,ko03010,map00240,map00400,map00410,map00740,map00770,map00900,map01100,map01110,map01130,map01230,map03010	M00022,M00052,M00096,M00119,M00125,M00178	R00158,R00161,R00512,R00549,R01665,R02473,R03460,R05884,R08210	RC00002,RC00017,RC00096,RC00141,RC00350,RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03009,ko03011			iPC815.YPO1391,iSDY_1059.SDY_2348	Bacteria	1V3IA@1239,4HFZE@91061,COG0283@1,COG0283@2	NA|NA|NA	F	Belongs to the cytidylate kinase family. Type 1 subfamily
NHHNPPIF_00171	264199.stu1134	5.9e-86	323.6	Bacilli	infC	GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767		ko:K02520					ko00000,ko03012,ko03029				Bacteria	1V1RC@1239,4HI4P@91061,COG0290@1,COG0290@2	NA|NA|NA	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NHHNPPIF_00172	264199.stu1133	8.1e-28	129.0	Bacilli	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904		ko:K02916	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1VF5W@1239,4HNIQ@91061,COG0291@1,COG0291@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL35 family
NHHNPPIF_00173	1046629.Ssal_01190	1.5e-56	225.3	Bacilli	rplT	GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141		ko:K02887	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V6DB@1239,4HH2W@91061,COG0292@1,COG0292@2	NA|NA|NA	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NHHNPPIF_00174	264199.stu1807	1.3e-84	318.9	Bacilli				ko:K07491					ko00000				Bacteria	1V1CM@1239,4HGN6@91061,COG1943@1,COG1943@2	NA|NA|NA	L	Transposase
NHHNPPIF_00175	264199.stu0061	2.3e-66	258.1	Bacilli	spxA_2		1.20.4.1	ko:K00537,ko:K16509					ko00000,ko01000				Bacteria	1VYBB@1239,4HWYC@91061,COG1393@1,COG1393@2	NA|NA|NA	P	Belongs to the ArsC family
NHHNPPIF_00176	322159.STER_0077	4.7e-205	720.3	Bacilli	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360		ko:K03553	ko03440,map03440	M00729			ko00000,ko00001,ko00002,ko03400				Bacteria	1TPD5@1239,4HAG5@91061,COG0468@1,COG0468@2	NA|NA|NA	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NHHNPPIF_00177	322159.STER_0076	1e-229	802.4	Bacilli	cinA	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760		R02322	RC00100	ko00000,ko00001,ko01000				Bacteria	1TQ1N@1239,4HATN@91061,COG1058@1,COG1058@2,COG1546@1,COG1546@2	NA|NA|NA	S	Belongs to the CinA family
NHHNPPIF_00178	322159.STER_0075	7.8e-105	386.3	Bacilli	tag		3.2.2.20	ko:K01246	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	1V9B8@1239,4HJ4I@91061,COG2818@1,COG2818@2	NA|NA|NA	L	3-methyladenine DNA glycosylase
NHHNPPIF_00179	322159.STER_0074	1.7e-102	378.6	Bacilli	ruvA	GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03550	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1V3KF@1239,4HHI5@91061,COG0632@1,COG0632@2	NA|NA|NA	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NHHNPPIF_00181	322159.STER_0072	0.0	1251.1	Bacilli	mutL	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391		ko:K03572	ko03430,map03430				ko00000,ko00001,ko03400				Bacteria	1TPGK@1239,4HB34@91061,COG0323@1,COG0323@2	NA|NA|NA	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NHHNPPIF_00183	904306.HMPREF9192_0027	7.9e-68	263.1	Bacilli													Bacteria	1VE2H@1239,4IPMG@91061,COG3279@1,COG3279@2	NA|NA|NA	K	LytTr DNA-binding domain
NHHNPPIF_00184	1046629.Ssal_02119	2.3e-78	298.1	Bacilli													Bacteria	1VHBQ@1239,2E0UI@1,32WBZ@2,4HRYH@91061	NA|NA|NA	S	Protein of unknown function (DUF3021)
NHHNPPIF_00185	322159.STER_0068	0.0	1627.8	Bacilli	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391		ko:K03555	ko03430,map03430				ko00000,ko00001,ko03400				Bacteria	1TPRJ@1239,4HA63@91061,COG0249@1,COG0249@2	NA|NA|NA	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NHHNPPIF_00186	264199.stu0049	1.5e-56	225.3	Bacilli	ymcA		3.6.3.21	ko:K02028		M00236			ko00000,ko00002,ko01000,ko02000	3.A.1.3			Bacteria	1V4W0@1239,4HH6Y@91061,COG4550@1,COG4550@2	NA|NA|NA	S	Belongs to the UPF0342 family
NHHNPPIF_00187	264199.stu0048	8.2e-70	269.6	Bacilli	argR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141		ko:K03402					ko00000,ko03000				Bacteria	1V1R7@1239,4HFY8@91061,COG1438@1,COG1438@2	NA|NA|NA	K	Regulates arginine biosynthesis genes
NHHNPPIF_00188	523794.Lebu_0405	1.1e-52	213.4	Bacteria													Bacteria	2E4MT@1,32ZGR@2	NA|NA|NA		
NHHNPPIF_00190	759913.SDSE_2235	2.8e-08	64.3	Streptococcus dysgalactiae group													Bacteria	1MA25@119603,1TXE0@1239,29I0Q@1,304XU@2,4I6C6@91061	NA|NA|NA		
NHHNPPIF_00193	322159.STER_0819	3.8e-295	1020.0	Bacilli				ko:K06919					ko00000				Bacteria	1UYRX@1239,4HC06@91061,COG3378@1,COG3378@2	NA|NA|NA	S	DNA primase
NHHNPPIF_00194	322159.STER_0820	1.7e-154	552.0	Bacteria				ko:K06919					ko00000				Bacteria	COG3378@1,COG3378@2	NA|NA|NA	KL	Phage plasmid primase P4 family
NHHNPPIF_00195	768726.HMPREF9178_1171	9e-22	109.4	Streptococcus mitis													Bacteria	1UEN1@1239,29UGX@1,2TPXS@28037,30FTY@2,4IE9Y@91061	NA|NA|NA		
NHHNPPIF_00200	904306.HMPREF9192_0303	5.5e-17	92.8	Bacilli		GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141		ko:K07729					ko00000,ko03000				Bacteria	1VK99@1239,4HR9G@91061,COG1476@1,COG1476@2	NA|NA|NA	K	TRANSCRIPTIONal
NHHNPPIF_00201	904306.HMPREF9192_0302	6e-39	167.5	Bacilli													Bacteria	1VK84@1239,4ISM2@91061,COG1396@1,COG1396@2	NA|NA|NA	K	Helix-turn-helix
NHHNPPIF_00202	322159.STER_0829	6.7e-215	753.1	Bacilli	sip												Bacteria	1TTJI@1239,4HDG6@91061,COG0582@1,COG0582@2	NA|NA|NA	L	Belongs to the 'phage' integrase family
NHHNPPIF_00203	322159.STER_0065	0.0	1107.8	Bacilli	argS		6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029				Bacteria	1TPEZ@1239,4HAR3@91061,COG0018@1,COG0018@2	NA|NA|NA	J	Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NHHNPPIF_00204	264199.stu0045	3.3e-247	860.5	Bacilli	purB	GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000			iLJ478.TM1095,iSB619.SA_RS09895	Bacteria	1TPMM@1239,4HACW@91061,COG0015@1,COG0015@2	NA|NA|NA	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NHHNPPIF_00205	585203.SMSK564_1384	1.2e-32	145.2	Streptococcus mitis													Bacteria	1VIUY@1239,2DZH9@1,2TPYM@28037,32VAR@2,4HZSZ@91061	NA|NA|NA		
NHHNPPIF_00206	264199.stu0043	2e-140	505.0	Firmicutes			1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000				Bacteria	1UD8U@1239,COG1893@1,COG1893@2	NA|NA|NA	H	Ketopantoate reductase
NHHNPPIF_00207	264199.stu0042	8.5e-204	716.1	Bacilli	purK		6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQCD@1239,4H9M5@91061,COG0026@1,COG0026@2	NA|NA|NA	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NHHNPPIF_00208	322159.STER_0059	4.9e-76	290.4	Bacilli	purE	GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000			iETEC_1333.ETEC_0575,iJN746.PP_5336,iPC815.YPO3076,iUTI89_1310.UTI89_C0551	Bacteria	1V1MV@1239,4HFR7@91061,COG0041@1,COG0041@2	NA|NA|NA	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NHHNPPIF_00209	264199.stu0040	2e-241	841.3	Bacilli	purD		6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000			iSB619.SA_RS05245,iYO844.BSU06530	Bacteria	1UHN9@1239,4HA70@91061,COG0151@1,COG0151@2	NA|NA|NA	F	Belongs to the GARS family
NHHNPPIF_00210	264199.stu0039	7.5e-160	569.7	Bacilli				ko:K21471					ko00000,ko01000,ko01002,ko01011				Bacteria	1VUNU@1239,4HVY0@91061,COG3942@1,COG3942@2	NA|NA|NA	S	CHAP domain
NHHNPPIF_00211	264199.stu0207	3.8e-31	140.2	Firmicutes				ko:K07497					ko00000				Bacteria	1TQQY@1239,COG2801@1,COG2801@2	NA|NA|NA	L	Integrase core domain protein
NHHNPPIF_00212	1069533.Sinf_0020	3.4e-24	117.1	Firmicutes													Bacteria	1TQ93@1239,COG3464@1,COG3464@2	NA|NA|NA	L	Transposase
NHHNPPIF_00213	264199.stu0493	2.7e-160	571.2	Bacilli	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.198	ko:K07056					ko00000,ko01000,ko03009				Bacteria	1TP6U@1239,4HAH8@91061,COG0313@1,COG0313@2	NA|NA|NA	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NHHNPPIF_00214	264199.stu0492	9.5e-55	219.2	Bacilli	yabA	GO:0003674,GO:0005488,GO:0005515,GO:0042802											Bacteria	1VA1F@1239,4HKND@91061,COG4467@1,COG4467@2	NA|NA|NA	L	Involved in initiation control of chromosome replication
NHHNPPIF_00215	904306.HMPREF9192_0407	8e-135	486.5	Bacilli	yaaT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464											Bacteria	1TP1V@1239,4H9M9@91061,COG1774@1,COG1774@2	NA|NA|NA	S	stage 0 sporulation protein
NHHNPPIF_00216	904306.HMPREF9192_0406	1.1e-156	559.3	Bacilli	holB		2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1TRVS@1239,4HA3T@91061,COG0470@1,COG0470@2	NA|NA|NA	L	dna polymerase iii
NHHNPPIF_00217	264199.stu0489	1.7e-111	408.7	Bacilli	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000			iSB619.SA_RS02535	Bacteria	1V1HE@1239,4HGWR@91061,COG0125@1,COG0125@2	NA|NA|NA	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NHHNPPIF_00218	264199.stu0488	3.4e-135	487.6	Bacilli	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147			iHN637.CLJU_RS19265	Bacteria	1TP2F@1239,4HAPT@91061,COG0149@1,COG0149@2	NA|NA|NA	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NHHNPPIF_00219	264199.stu0487	3.6e-224	783.9	Bacilli	tuf	GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009274,GO:0009275,GO:0009986,GO:0010339,GO:0016020,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035821,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484		ko:K02358,ko:K15771	ko02010,map02010	M00491			ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	3.A.1.1.16,3.A.1.1.2			Bacteria	1TPKC@1239,4HAEH@91061,COG0050@1,COG0050@2	NA|NA|NA	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NHHNPPIF_00220	264199.stu0486	7.5e-228	796.2	Bacilli	ftsW			ko:K03588	ko04112,map04112				ko00000,ko00001,ko02000,ko03036	2.A.103.1			Bacteria	1TPT7@1239,4HAEV@91061,COG0772@1,COG0772@2	NA|NA|NA	D	Belongs to the SEDS family
NHHNPPIF_00221	264199.stu0485	2e-52	211.8	Bacilli	atpC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600		ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194	3.A.2.1		iJN746.PP_5412,iSbBS512_1146.SbBS512_E4190	Bacteria	1VA89@1239,4HKHS@91061,COG0355@1,COG0355@2	NA|NA|NA	C	Produces ATP from ADP in the presence of a proton gradient across the membrane
NHHNPPIF_00222	322159.STER_0521	6.1e-263	912.9	Bacilli	atpD		3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1		iSB619.SA_RS10965	Bacteria	1TPGF@1239,4HAT6@91061,COG0055@1,COG0055@2	NA|NA|NA	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NHHNPPIF_00223	264199.stu0483	6.2e-157	560.1	Bacilli	atpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194	3.A.2.1		iLJ478.TM1611,iSB619.SA_RS10970,iYO844.BSU36820	Bacteria	1TPBX@1239,4HB0E@91061,COG0224@1,COG0224@2	NA|NA|NA	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NHHNPPIF_00224	264199.stu0482	2.5e-278	964.1	Bacilli	atpA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1		iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187	Bacteria	1TNZ8@1239,4HAMZ@91061,COG0056@1,COG0056@2	NA|NA|NA	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NHHNPPIF_00225	264199.stu0481	1e-85	322.8	Bacilli	atpH	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600		ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194	3.A.2.1		iSF_1195.SF3815,iSFxv_1172.SFxv_4157,iS_1188.S3953	Bacteria	1VAG3@1239,4HKW1@91061,COG0712@1,COG0712@2	NA|NA|NA	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHHNPPIF_00226	264199.stu0480	2.3e-76	291.6	Firmicutes	atpF			ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194	3.A.2.1		iHN637.CLJU_RS01170,iYO844.BSU36850	Bacteria	1V74A@1239,COG0711@1,COG0711@2	NA|NA|NA	C	ATP synthase F(0) sector subunit b
NHHNPPIF_00227	322159.STER_0516	1.6e-123	448.7	Bacilli	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600		ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1		iAPECO1_1312.APECO1_2725,iE2348C_1286.E2348C_4048,iEC042_1314.EC042_4125,iECABU_c1320.ECABU_c42230,iECED1_1282.ECED1_4428,iECIAI39_1322.ECIAI39_4342,iECNA114_1301.ECNA114_3887,iECOK1_1307.ECOK1_4187,iECP_1309.ECP_3937,iECS88_1305.ECS88_4160,iECSF_1327.ECSF_3586,iECUMN_1333.ECUMN_4268,iEcSMS35_1347.EcSMS35_4106,iLF82_1304.LF82_0192,iNRG857_1313.NRG857_18615,iUMN146_1321.UM146_18880,iUMNK88_1353.UMNK88_4550,iUTI89_1310.UTI89_C4293,ic_1306.c4666	Bacteria	1TQIT@1239,4H9NV@91061,COG0356@1,COG0356@2	NA|NA|NA	C	it plays a direct role in the translocation of protons across the membrane
NHHNPPIF_00228	1123298.KB904069_gene1213	1.4e-16	91.7	Bacteria	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600		ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157			ko00000,ko00001,ko00002,ko00194	3.A.2.1			Bacteria	2ZI0B@2,COG0636@1	NA|NA|NA	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHHNPPIF_00229	322159.STER_0513	0.0	1745.3	Bacilli	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iLJ478.TM1817	Bacteria	1TPN4@1239,4HB85@91061,COG0525@1,COG0525@2	NA|NA|NA	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NHHNPPIF_00230	322159.STER_0512	8.1e-69	266.2	Bacteria			2.3.1.128,5.2.1.8	ko:K03768,ko:K03790					ko00000,ko01000,ko03009,ko03110				Bacteria	COG1670@1,COG1670@2	NA|NA|NA	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NHHNPPIF_00231	322159.STER_0511	8.3e-105	386.3	Bacilli													Bacteria	1VENC@1239,4HQ31@91061,COG1853@1,COG1853@2	NA|NA|NA	S	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NHHNPPIF_00232	1123314.AUIO01000005_gene141	8.9e-14	82.4	Bacilli	coiA		3.6.4.12	ko:K03657,ko:K06198	ko03420,ko03430,map03420,map03430				ko00000,ko00001,ko01000,ko03400				Bacteria	1TRGD@1239,4HFP5@91061,COG4469@1,COG4469@2	NA|NA|NA	S	Competence protein
NHHNPPIF_00233	1123315.AUIP01000020_gene2219	2.6e-16	92.4	Bacteria													Bacteria	COG3212@1,COG3212@2	NA|NA|NA	T	peptidase
NHHNPPIF_00234	264199.stu0471	1e-151	542.7	Bacilli	rarD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944		ko:K05786					ko00000,ko02000	2.A.7.7			Bacteria	1TQF2@1239,4HAYU@91061,COG2962@1,COG2962@2	NA|NA|NA	S	Transporter
NHHNPPIF_00235	1046629.Ssal_01693	4.2e-150	537.3	Bacilli	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000			iECSE_1348.ECSE_0003,iJN678.thrB,iLJ478.TM0545	Bacteria	1TRWS@1239,4HCQN@91061,COG0083@1,COG0083@2	NA|NA|NA	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NHHNPPIF_00236	264199.stu0469	4e-237	827.0	Bacilli	hom	GO:0003674,GO:0003824,GO:0004412,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000			iNJ661.Rv1294,iSB619.SA_RS06610	Bacteria	1TQ2H@1239,4HBAP@91061,COG0460@1,COG0460@2	NA|NA|NA	E	homoserine dehydrogenase
NHHNPPIF_00237	322159.STER_0504	2.5e-129	468.4	Bacilli	yxkH												Bacteria	1V6AW@1239,4HHC9@91061,COG0726@1,COG0726@2	NA|NA|NA	G	deacetylase
NHHNPPIF_00238	322159.STER_0503	5.3e-209	733.4	Bacilli	argD	GO:0003674,GO:0003824,GO:0003992,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	1TP9S@1239,4H9VZ@91061,COG4992@1,COG4992@2	NA|NA|NA	E	acetylornithine aminotransferase
NHHNPPIF_00239	264199.stu0466	1.2e-129	469.2	Firmicutes	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP0N@1239,COG0548@1,COG0548@2	NA|NA|NA	E	Belongs to the acetylglutamate kinase family. ArgB subfamily
NHHNPPIF_00240	322159.STER_0501	1.5e-222	778.5	Bacilli	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35,2.7.2.8	ko:K00620,ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282,R02649	RC00002,RC00004,RC00043,RC00064	ko00000,ko00001,ko00002,ko01000			iLJ478.TM1783	Bacteria	1TPBP@1239,4H9TQ@91061,COG1364@1,COG1364@2	NA|NA|NA	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NHHNPPIF_00241	264199.stu0464	1.4e-189	668.7	Bacilli	argC	GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000			iLJ478.TM1782,iSSON_1240.SSON_4131,iYO844.BSU11190	Bacteria	1TPVI@1239,4H9YD@91061,COG0002@1,COG0002@2	NA|NA|NA	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NHHNPPIF_00242	322159.STER_0499	1.7e-226	791.6	Bacilli	mtnE		2.6.1.83	ko:K08969,ko:K10206	ko00270,ko00300,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map01100,map01110,map01130,map01230	M00034,M00527	R07396,R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	1TQD6@1239,4HAHQ@91061,COG0436@1,COG0436@2	NA|NA|NA	E	mutations do not affect methionine salvage in vivo however
NHHNPPIF_00243	264199.stu0462	4.9e-145	520.4	Bacilli	cnhA		3.5.1.3	ko:K11206,ko:K13566	ko00250,map00250		R00269,R00348	RC00010	ko00000,ko00001,ko01000				Bacteria	1TQDK@1239,4HC44@91061,COG0388@1,COG0388@2	NA|NA|NA	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NHHNPPIF_00244	264199.stu0461	1.3e-30	138.3	Bacteria			3.4.17.14,3.5.1.28	ko:K01448,ko:K02395,ko:K07260	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	M00651,M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036				Bacteria	COG1705@1,COG1705@2	NA|NA|NA	NU	amidase activity
NHHNPPIF_00245	264199.stu0461	3.4e-41	174.9	Bacteria			3.4.17.14,3.5.1.28	ko:K01448,ko:K02395,ko:K07260	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	M00651,M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036				Bacteria	COG1705@1,COG1705@2	NA|NA|NA	NU	amidase activity
NHHNPPIF_00246	322159.STER_0495	2.5e-146	525.0	Bacilli			3.4.17.14,3.5.1.28	ko:K01448,ko:K07260,ko:K21471	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	M00651,M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko03036				Bacteria	1W25V@1239,4HGXW@91061,COG0860@1,COG0860@2,COG3942@1,COG3942@2	NA|NA|NA	M	GBS Bsp-like repeat
NHHNPPIF_00247	264199.stu0457	0.0	1717.6	Bacilli	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1TPK6@1239,4H9XC@91061,COG0013@1,COG0013@2	NA|NA|NA	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NHHNPPIF_00248	862969.SCI_0200	8.9e-163	580.1	Streptococcus anginosus group													Bacteria	1V8H0@1239,2AQ9M@1,31FFI@2,42EJB@671232,4ISNC@91061	NA|NA|NA	S	Uncharacterised protein family (UPF0236)
NHHNPPIF_00249	176090.SSIN_1129	9.5e-126	456.4	Firmicutes													Bacteria	1UIB2@1239,COG3177@1,COG3177@2	NA|NA|NA	S	Fic/DOC family
NHHNPPIF_00251	862970.SAIN_0380	4.5e-114	417.5	Bacilli				ko:K03496					ko00000,ko03036,ko04812				Bacteria	1V6Q6@1239,4HINH@91061,COG1192@1,COG1192@2	NA|NA|NA	D	CobQ CobB MinD ParA nucleotide binding domain protein
NHHNPPIF_00253	1035184.HMPREF1042_2326	1.3e-73	282.7	Streptococcus anginosus group	tnpR												Bacteria	1UZM8@1239,42EG7@671232,4IQ67@91061,COG1961@1,COG1961@2	NA|NA|NA	L	Resolvase, N terminal domain
NHHNPPIF_00256	862969.SCI_0195	1.4e-183	649.0	Streptococcus anginosus group													Bacteria	1V2SB@1239,42E61@671232,4HFEX@91061,COG3843@1,COG3843@2	NA|NA|NA	U	Relaxase/Mobilisation nuclease domain
NHHNPPIF_00257	264199.stu1020	4.6e-25	119.8	Bacteria	tatA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944		ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336			ko00000,ko00001,ko00002,ko02044	2.A.64			Bacteria	COG1826@1,COG1826@2	NA|NA|NA	U	protein secretion
NHHNPPIF_00258	322159.STER_1021	4.4e-121	440.7	Bacilli	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680		ko:K03118	ko03060,ko03070,map03060,map03070	M00336			ko00000,ko00001,ko00002,ko02044	2.A.64			Bacteria	1U7N7@1239,4HB1U@91061,COG0805@1,COG0805@2	NA|NA|NA	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NHHNPPIF_00259	322159.STER_1022	3e-301	1040.4	Bacilli	ywbL			ko:K07243					ko00000,ko02000	2.A.108.1,2.A.108.2			Bacteria	1TQIA@1239,4HCJZ@91061,COG0672@1,COG0672@2	NA|NA|NA	P	COG0672 High-affinity Fe2 Pb2 permease
NHHNPPIF_00260	322159.STER_1023	5.6e-233	813.1	Bacilli	ycdB			ko:K16301					ko00000,ko01000,ko02000	2.A.108.2.3			Bacteria	1UY9Y@1239,4HACQ@91061,COG2837@1,COG2837@2	NA|NA|NA	P	peroxidase
NHHNPPIF_00261	322159.STER_1024	3.2e-153	547.7	Bacilli	ycdO	GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0008150,GO:0015684,GO:0030001,GO:0051179,GO:0051234,GO:0070838,GO:0072511		ko:K07224,ko:K07243					ko00000,ko02000	2.A.108.1,2.A.108.2,2.A.108.2.3			Bacteria	1TS89@1239,4HB0W@91061,COG2822@1,COG2822@2	NA|NA|NA	P	periplasmic lipoprotein involved in iron transport
NHHNPPIF_00262	1046629.Ssal_01131	1.2e-33	149.1	Bacilli	pulA		3.2.1.1,3.2.1.41	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973		R02108,R02111,R02112,R11262		ko00000,ko00001,ko01000		CBM48,GH13		Bacteria	1TP3M@1239,4HBP5@91061,COG1523@1,COG1523@2	NA|NA|NA	G	belongs to the glycosyl hydrolase 13 family
NHHNPPIF_00263	264199.stu1031	3.7e-85	320.9	Bacilli	pulA		3.2.1.1,3.2.1.41	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973		R02108,R02111,R02112,R11262		ko00000,ko00001,ko01000		CBM48,GH13		Bacteria	1TP3M@1239,4HBP5@91061,COG1523@1,COG1523@2	NA|NA|NA	G	belongs to the glycosyl hydrolase 13 family
NHHNPPIF_00264	1046629.Ssal_01131	1.7e-60	238.4	Bacilli	pulA		3.2.1.1,3.2.1.41	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973		R02108,R02111,R02112,R11262		ko00000,ko00001,ko01000		CBM48,GH13		Bacteria	1TP3M@1239,4HBP5@91061,COG1523@1,COG1523@2	NA|NA|NA	G	belongs to the glycosyl hydrolase 13 family
NHHNPPIF_00265	264199.stu1033	7.6e-66	256.5	Bacilli	pulA		3.2.1.1,3.2.1.41	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973		R02108,R02111,R02112,R11262		ko00000,ko00001,ko01000		CBM48,GH13		Bacteria	1TP3M@1239,4HBP5@91061,COG1523@1,COG1523@2	NA|NA|NA	G	belongs to the glycosyl hydrolase 13 family
NHHNPPIF_00266	1046629.Ssal_01131	1.5e-133	482.3	Bacilli	pulA		3.2.1.1,3.2.1.41	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973		R02108,R02111,R02112,R11262		ko00000,ko00001,ko01000		CBM48,GH13		Bacteria	1TP3M@1239,4HBP5@91061,COG1523@1,COG1523@2	NA|NA|NA	G	belongs to the glycosyl hydrolase 13 family
NHHNPPIF_00267	322159.STER_1030	1.6e-185	655.2	Bacilli			3.5.1.28	ko:K01448,ko:K07273	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036				Bacteria	1W25V@1239,4HGXW@91061,COG0860@1,COG0860@2	NA|NA|NA	M	GBS Bsp-like repeat
NHHNPPIF_00268	264199.stu1046	1.9e-65	255.0	Bacteria			3.2.1.17	ko:K01185,ko:K07273					ko00000,ko01000				Bacteria	COG3757@1,COG3757@2	NA|NA|NA	M	lysozyme activity
NHHNPPIF_00269	904306.HMPREF9192_1715	9.9e-12	75.9	Bacteria			3.5.1.28	ko:K01448,ko:K02395,ko:K21471	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036				Bacteria	COG0860@1,COG0860@2,COG1705@1,COG1705@2,COG3757@1,COG3757@2,COG5263@1,COG5263@2	NA|NA|NA	NU	amidase activity
NHHNPPIF_00270	322159.STER_1033	0.0	1106.7	Bacilli	lpdA		1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1TP1W@1239,4H9Z5@91061,COG1249@1,COG1249@2	NA|NA|NA	C	Dehydrogenase
NHHNPPIF_00271	264199.stu1049	1.3e-198	699.1	Bacilli	acoC		2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	1TR5N@1239,4HDFT@91061,COG0508@1,COG0508@2	NA|NA|NA	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NHHNPPIF_00272	264199.stu1050	3.7e-182	644.0	Bacilli	acoB		1.2.4.1,1.2.4.4	ko:K00162,ko:K11381,ko:K21417	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	1TP3J@1239,4HAP6@91061,COG0022@1,COG0022@2	NA|NA|NA	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NHHNPPIF_00273	322159.STER_1036	1.7e-184	651.7	Bacilli	acoA		1.2.4.1,1.2.4.4	ko:K00161,ko:K11381,ko:K21416	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	1TQDG@1239,4HBEA@91061,COG1071@1,COG1071@2	NA|NA|NA	C	Dehydrogenase E1 component
NHHNPPIF_00274	1046629.Ssal_01151	0.0	1139.4	Bacilli													Bacteria	1TS3Q@1239,4HF7D@91061,COG4907@1,COG4907@2	NA|NA|NA	S	the current gene model (or a revised gene model) may contain a frame shift
NHHNPPIF_00275	264199.stu1054	1.8e-234	818.1	Bacilli	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPQM@1239,4HA90@91061,COG0044@1,COG0044@2	NA|NA|NA	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NHHNPPIF_00276	322159.STER_1041	2.2e-127	461.5	Firmicutes	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340				ko00000,ko00001,ko01000,ko03400				Bacteria	1TPSN@1239,COG0692@1,COG0692@2	NA|NA|NA	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NHHNPPIF_00277	322159.STER_1042	1.6e-216	758.4	Bacilli	yeaB												Bacteria	1TSGY@1239,4H9WP@91061,COG0053@1,COG0053@2,COG4994@1,COG4994@2	NA|NA|NA	K	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NHHNPPIF_00278	264199.stu1058	2.9e-21	107.1	Bacteria	dacA1		3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100				ko00000,ko00001,ko01000,ko01002,ko01011				Bacteria	COG1686@1,COG1686@2	NA|NA|NA	M	Belongs to the peptidase S11 family
NHHNPPIF_00279	264199.stu1059	3.9e-24	116.7	Bacilli			3.4.16.4	ko:K01286					ko00000,ko01000				Bacteria	1TQN0@1239,4HD0P@91061,COG1686@1,COG1686@2	NA|NA|NA	M	Belongs to the peptidase S11 family
NHHNPPIF_00280	264199.stu1059	4.1e-127	460.7	Bacilli			3.4.16.4	ko:K01286					ko00000,ko01000				Bacteria	1TQN0@1239,4HD0P@91061,COG1686@1,COG1686@2	NA|NA|NA	M	Belongs to the peptidase S11 family
NHHNPPIF_00281	322159.STER_1044	1.2e-157	562.4	Bacilli	rssA												Bacteria	1TQ9W@1239,4HCHJ@91061,COG4667@1,COG4667@2	NA|NA|NA	S	Phospholipase, patatin family
NHHNPPIF_00282	322159.STER_1045	1.8e-69	268.5	Bacilli	estA												Bacteria	1V1B9@1239,4HGED@91061,COG2755@1,COG2755@2	NA|NA|NA	E	GDSL-like protein
NHHNPPIF_00283	904306.HMPREF9192_1701	3.4e-29	133.7	Bacilli	estA												Bacteria	1VHUN@1239,4IPN1@91061,COG2755@1,COG2755@2	NA|NA|NA	E	Lysophospholipase L1 and related esterases
NHHNPPIF_00284	322159.STER_1047	7e-292	1009.2	Bacilli				ko:K03688					ko00000				Bacteria	1TPIV@1239,4HBW3@91061,COG0661@1,COG0661@2	NA|NA|NA	S	unusual protein kinase
NHHNPPIF_00285	322159.STER_1048	4.9e-39	166.8	Bacilli													Bacteria	1VK6K@1239,4HRS5@91061,COG3937@1,COG3937@2	NA|NA|NA	S	granule-associated protein
NHHNPPIF_00286	1046629.Ssal_01160	4.6e-138	497.3	Bacilli	bglH		3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500		R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000		GT1		Bacteria	1TP19@1239,4HA1W@91061,COG2723@1,COG2723@2	NA|NA|NA	G	Belongs to the glycosyl hydrolase 1 family
NHHNPPIF_00287	1123318.KB904593_gene1608	2e-18	97.4	Bacilli	bglH		3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500		R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000		GT1		Bacteria	1TP19@1239,4HA1W@91061,COG2723@1,COG2723@2	NA|NA|NA	G	Belongs to the glycosyl hydrolase 1 family
NHHNPPIF_00288	322159.STER_1050	1.3e-199	702.2	Bacilli													Bacteria	1TQBF@1239,4HGFS@91061,COG0628@1,COG0628@2	NA|NA|NA	S	hmm pf01594
NHHNPPIF_00289	1046629.Ssal_01162	2.5e-101	374.8	Bacilli													Bacteria	1UXY8@1239,4HFD9@91061,COG0406@1,COG0406@2	NA|NA|NA	G	Belongs to the phosphoglycerate mutase family
NHHNPPIF_00290	264199.stu1071	3.7e-60	237.3	Bacteria	supH		3.1.3.102,3.1.3.104	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00548,R07280	RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	COG0561@1,COG0561@2	NA|NA|NA	Q	phosphatase activity
NHHNPPIF_00291	1046629.Ssal_01165	1.1e-15	88.6	Bacilli	supH		3.1.3.102,3.1.3.104	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00548,R07280	RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	1V1SQ@1239,4IPTG@91061,COG0561@1,COG0561@2	NA|NA|NA	S	Sucrose-6F-phosphate phosphohydrolase
NHHNPPIF_00292	322159.STER_1054	2.2e-94	351.7	Bacilli													Bacteria	1VA6K@1239,4HKNU@91061,COG4767@1,COG4767@2	NA|NA|NA	V	VanZ like family
NHHNPPIF_00293	1008453.HMPREF9957_1401	5.1e-21	107.1	Streptococcus mitis				ko:K07497					ko00000				Bacteria	1TRR6@1239,2TP00@28037,4HAJS@91061,COG2801@1,COG2801@2	NA|NA|NA	L	overlaps another CDS with the same product name
NHHNPPIF_00294	1423734.JCM14202_2269	1.7e-44	186.8	Bacilli													Bacteria	1UZT5@1239,4IPKX@91061,COG0640@1,COG0640@2	NA|NA|NA	K	helix_turn_helix, Arsenical Resistance Operon Repressor
NHHNPPIF_00295	904306.HMPREF9192_0991	6.3e-160	570.1	Bacilli	yrdR												Bacteria	1UZGC@1239,4HDET@91061,COG0697@1,COG0697@2	NA|NA|NA	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NHHNPPIF_00296	575606.HMPREF0525_01168	1.2e-71	276.6	Lactobacillaceae			2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000				Bacteria	1TSNU@1239,3F3JH@33958,4H9TY@91061,COG1085@1,COG1085@2	NA|NA|NA	C	Domain of unknown function (DUF4931)
NHHNPPIF_00297	904306.HMPREF9192_0989	6.8e-153	546.6	Firmicutes													Bacteria	1UKB6@1239,COG1735@1,COG1735@2	NA|NA|NA	S	metal-dependent hydrolase with the TIM-barrel fold
NHHNPPIF_00298	904306.HMPREF9192_0988	7.7e-123	446.4	Bacilli	dlpA												Bacteria	1V1ME@1239,4HGQE@91061,COG0684@1,COG0684@2	NA|NA|NA	H	Methyltransferase
NHHNPPIF_00299	904306.HMPREF9192_0987	4e-209	733.8	Bacilli	dlpA		1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	1TPEM@1239,4HA76@91061,COG0473@1,COG0473@2	NA|NA|NA	CE	Tartrate dehydrogenase
NHHNPPIF_00301	904306.HMPREF9192_0984	1.3e-160	572.4	Bacilli			4.1.3.39	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R00750	RC00307,RC00371	br01602,ko00000,ko00001,ko00002,ko01000				Bacteria	1TS0A@1239,4HAXZ@91061,COG0119@1,COG0119@2	NA|NA|NA	E	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds
NHHNPPIF_00302	264199.stu0018	2.3e-48	198.4	Bacteria				ko:K07497					ko00000				Bacteria	COG2801@1,COG2801@2	NA|NA|NA	L	transposition
NHHNPPIF_00303	1095738.HMPREF1047_1210	1e-16	92.0	Firmicutes				ko:K07483					ko00000				Bacteria	1W68S@1239,COG2963@1,COG2963@2	NA|NA|NA	L	Transposase
NHHNPPIF_00304	322159.STER_0016	1.2e-61	242.3	Firmicutes				ko:K07483					ko00000				Bacteria	1W68S@1239,COG2963@1,COG2963@2	NA|NA|NA	L	Transposase
NHHNPPIF_00305	264199.stu0204	1.1e-284	985.3	Bacilli	groL	GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065		ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152				ko00000,ko00001,ko03019,ko03029,ko03110,ko04147				Bacteria	1TP1T@1239,4HA38@91061,COG0459@1,COG0459@2	NA|NA|NA	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NHHNPPIF_00306	264199.stu0203	3.2e-41	174.1	Bacteria	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0032991,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:0101031,GO:1903506,GO:1990220,GO:2000112,GO:2001141		ko:K04078					ko00000,ko03029,ko03110				Bacteria	COG0234@1,COG0234@2	NA|NA|NA	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NHHNPPIF_00307	264199.stu0202	7.5e-141	506.5	Bacilli	cmpC			ko:K05833		M00247			ko00000,ko00002,ko02000				Bacteria	1TPAN@1239,4HCHC@91061,COG1101@1,COG1101@2	NA|NA|NA	S	abc transporter atp-binding protein
NHHNPPIF_00308	264199.stu0201	0.0	1137.9	Firmicutes	WQ51_06230			ko:K01989,ko:K05832		M00247			ko00000,ko00002,ko02000				Bacteria	1TPB0@1239,COG2984@1,COG2984@2,COG4120@1,COG4120@2	NA|NA|NA	S	ABC transporter substrate binding protein
NHHNPPIF_00309	264199.stu0200	0.0	1207.6	Bacilli	proS	GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iJN678.proS,iUTI89_1310.UTI89_C0210	Bacteria	1TRBV@1239,4H9NN@91061,COG0442@1,COG0442@2	NA|NA|NA	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NHHNPPIF_00310	322159.STER_0246	7.2e-231	806.2	Bacilli	rseP	GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0040007,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	3.4.21.107,3.4.21.116	ko:K04771,ko:K06399,ko:K11749,ko:K16922	ko01503,ko02020,ko02024,ko04112,map01503,map02020,map02024,map04112	M00728			ko00000,ko00001,ko00002,ko01000,ko01002,ko03110				Bacteria	1TPMC@1239,4HAQ5@91061,COG0750@1,COG0750@2	NA|NA|NA	M	zinc metalloprotease
NHHNPPIF_00311	264199.stu0198	5e-145	520.4	Bacilli	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000			iSB619.SA_RS06255	Bacteria	1TT0Q@1239,4HAMN@91061,COG4589@1,COG4589@2	NA|NA|NA	S	Belongs to the CDS family
NHHNPPIF_00312	264199.stu0197	5.3e-141	506.9	Bacilli	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110		R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006				Bacteria	1TQTS@1239,4HA37@91061,COG0020@1,COG0020@2	NA|NA|NA	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NHHNPPIF_00313	264199.stu0196	2.4e-48	198.0	Bacteria	yajC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944		ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2			Bacteria	COG1862@1,COG1862@2	NA|NA|NA	U	protein transport
NHHNPPIF_00314	264199.stu0195	1.9e-127	461.8	Bacilli	yeeN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464											Bacteria	1TPP5@1239,4H9WJ@91061,COG0217@1,COG0217@2	NA|NA|NA	K	transcriptional regulatory protein
NHHNPPIF_00315	264199.stu0194	6.9e-256	889.4	Bacilli	pgi	GO:0003674,GO:0003824,GO:0004347,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147			iLJ478.TM1385	Bacteria	1TP29@1239,4H9VI@91061,COG0166@1,COG0166@2	NA|NA|NA	G	Belongs to the GPI family
NHHNPPIF_00316	264199.stu0193	9.8e-157	559.3	Bacilli	rgfB		3.1.3.90	ko:K06896	ko00500,map00500		R10486	RC00017	ko00000,ko00001,ko01000				Bacteria	1TQZG@1239,4HGS5@91061,COG3568@1,COG3568@2	NA|NA|NA	L	Endonuclease/Exonuclease/phosphatase family
NHHNPPIF_00317	435842.HMPREF0848_01513	4.2e-257	893.6	Bacilli	ptsG		2.7.1.199,2.7.1.208	ko:K02777,ko:K02778,ko:K02779,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	M00265,M00266,M00268,M00270,M00272,M00303,M00806	R02738,R02780,R04111,R04394,R05132,R08559	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1,4.A.1.1.11,4.A.1.1.12			Bacteria	1TPJ8@1239,4HA8X@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2	NA|NA|NA	G	pts system
NHHNPPIF_00318	435842.HMPREF0848_01513	9.2e-25	119.0	Bacilli	ptsG		2.7.1.199,2.7.1.208	ko:K02777,ko:K02778,ko:K02779,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	M00265,M00266,M00268,M00270,M00272,M00303,M00806	R02738,R02780,R04111,R04394,R05132,R08559	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1,4.A.1.1.11,4.A.1.1.12			Bacteria	1TPJ8@1239,4HA8X@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2	NA|NA|NA	G	pts system
NHHNPPIF_00319	264199.stu0189	1.3e-64	252.3	Bacilli	ptsG		2.7.1.199,2.7.1.208	ko:K02777,ko:K02778,ko:K02779,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	M00265,M00266,M00268,M00270,M00272,M00303,M00806	R02738,R02780,R04111,R04394,R05132,R08559	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1,4.A.1.1.11,4.A.1.1.12			Bacteria	1TPJ8@1239,4HA8X@91061,COG1263@1,COG1263@2	NA|NA|NA	G	pts system
NHHNPPIF_00320	264199.stu0188	2.1e-163	581.6	Bacilli	mleP2			ko:K07088					ko00000				Bacteria	1UY4N@1239,4HB48@91061,COG0679@1,COG0679@2	NA|NA|NA	S	Transporter, auxin efflux carrier (AEC) family protein
NHHNPPIF_00321	322159.STER_0235	1.9e-128	465.3	Bacilli	adcB	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944		ko:K09816	ko02010,map02010	M00242			ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5			Bacteria	1TR79@1239,4HC3C@91061,COG1108@1,COG1108@2	NA|NA|NA	P	ABC transporter (Permease
NHHNPPIF_00322	264199.stu0186	2.2e-136	491.5	Bacilli	adcC			ko:K09817	ko02010,map02010	M00242			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5		iHN637.CLJU_RS15665,iYO844.BSU02860	Bacteria	1TQ68@1239,4HAZI@91061,COG1121@1,COG1121@2	NA|NA|NA	P	ABC transporter, ATP-binding protein
NHHNPPIF_00323	264199.stu0185	3.1e-72	277.7	Bacilli	adcR												Bacteria	1VXZT@1239,4HXMU@91061,COG1846@1,COG1846@2	NA|NA|NA	K	transcriptional
NHHNPPIF_00324	264199.stu0184	1.9e-223	781.6	Bacilli													Bacteria	1UG5D@1239,2ZBIK@2,4H9W5@91061,COG0477@1	NA|NA|NA	EGP	Major facilitator Superfamily
NHHNPPIF_00325	264199.stu0183	0.0	1566.6	Bacilli													Bacteria	1V7E2@1239,4HJ1U@91061,COG0515@1,COG0515@2	NA|NA|NA	KLT	serine threonine protein kinase
NHHNPPIF_00326	264199.stu0182	3e-127	461.5	Bacteria				ko:K20374,ko:K21405	ko02024,map02024				ko00000,ko00001,ko03000				Bacteria	COG1396@1,COG1396@2	NA|NA|NA	K	sequence-specific DNA binding
NHHNPPIF_00327	322159.STER_0231	7.4e-183	646.4	Bacilli	dus			ko:K05540					ko00000,ko01000,ko03016				Bacteria	1TQ2R@1239,4HA9K@91061,COG0042@1,COG0042@2	NA|NA|NA	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NHHNPPIF_00328	322159.STER_0230	1.9e-158	565.1	Bacilli	hslO	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0031647,GO:0036506,GO:0042026,GO:0042802,GO:0043167,GO:0043169,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0065007,GO:0065008		ko:K04083					ko00000,ko03110				Bacteria	1TRCH@1239,4HAFR@91061,COG1281@1,COG1281@2	NA|NA|NA	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NHHNPPIF_00329	1123311.KB904471_gene1168	7.4e-10	69.7	Bacilli													Bacteria	1W24H@1239,2DCPN@1,2ZEV1@2,4HZKX@91061	NA|NA|NA		
NHHNPPIF_00331	322159.STER_0227	1.4e-87	328.9	Bacilli	oppF			ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1V36J@1239,4H9YB@91061,COG4608@1,COG4608@2	NA|NA|NA	P	Belongs to the ABC transporter superfamily
NHHNPPIF_00332	264199.stu0178	2.2e-61	241.5	Bacilli	oppF			ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1V36J@1239,4H9YB@91061,COG4608@1,COG4608@2	NA|NA|NA	P	Belongs to the ABC transporter superfamily
NHHNPPIF_00333	264199.stu0177	1.1e-43	182.2	Bacilli	oppD			ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1TP6E@1239,4HA4E@91061,COG0444@1,COG0444@2	NA|NA|NA	P	Belongs to the ABC transporter superfamily
NHHNPPIF_00334	264199.stu0176	1.1e-68	265.8	Bacilli	oppD			ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1TP6E@1239,4HA4E@91061,COG0444@1,COG0444@2	NA|NA|NA	P	Belongs to the ABC transporter superfamily
NHHNPPIF_00335	264199.stu0175	2.5e-32	144.1	Bacteria	oppD			ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	COG0444@1,COG0444@2	NA|NA|NA	P	Belongs to the ABC transporter superfamily
NHHNPPIF_00336	264199.stu0174	3e-27	127.1	Bacteria	oppD			ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	COG0444@1,COG0444@2	NA|NA|NA	P	Belongs to the ABC transporter superfamily
NHHNPPIF_00337	264199.stu0173	1.4e-38	165.2	Bacilli	oppC			ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1TP4R@1239,4H9PZ@91061,COG1173@1,COG1173@2	NA|NA|NA	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHHNPPIF_00338	1046629.Ssal_02002	2.5e-09	66.6	Bacilli	oppC			ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1TP4R@1239,4H9PZ@91061,COG1173@1,COG1173@2	NA|NA|NA	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHHNPPIF_00340	1046629.Ssal_02003	8.5e-28	129.0	Bacilli	oppB			ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1TP1S@1239,4HA2S@91061,COG0601@1,COG0601@2	NA|NA|NA	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHHNPPIF_00341	264199.stu0170	1.1e-125	456.1	Bacilli	oppA			ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1TNYQ@1239,4HAMK@91061,COG4166@1,COG4166@2	NA|NA|NA	E	ABC transporter substrate-binding protein
NHHNPPIF_00342	435842.HMPREF0848_01501	9.7e-19	99.0	Bacilli	oppA			ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1TNYQ@1239,4HAMK@91061,COG4166@1,COG4166@2	NA|NA|NA	E	ABC transporter substrate-binding protein
NHHNPPIF_00343	264199.stu0168	2.2e-273	947.6	Bacilli	sufB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360		ko:K07033,ko:K09014					ko00000				Bacteria	1TQ21@1239,4HA1Z@91061,COG0719@1,COG0719@2	NA|NA|NA	O	assembly protein SufB
NHHNPPIF_00344	264199.stu0167	2.1e-73	281.6	Bacilli	nifU	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564		ko:K04488					ko00000				Bacteria	1V3H9@1239,4HIJ0@91061,COG0822@1,COG0822@2	NA|NA|NA	C	SUF system FeS assembly protein, NifU family
NHHNPPIF_00345	264199.stu0166	2.3e-237	827.8	Bacilli	sufS		2.8.1.7,4.4.1.16	ko:K04487,ko:K11717	ko00450,ko00730,ko01100,ko04122,map00450,map00730,map01100,map04122		R03599,R07460,R11528,R11529	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029				Bacteria	1TQ1W@1239,4HA6Z@91061,COG0520@1,COG0520@2	NA|NA|NA	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NHHNPPIF_00346	322159.STER_0219	6.3e-235	819.7	Bacilli	sufD			ko:K07033,ko:K09015					ko00000				Bacteria	1TRT0@1239,4HB6W@91061,COG0719@1,COG0719@2	NA|NA|NA	O	assembly protein SufD
NHHNPPIF_00347	264199.stu0164	9.5e-144	516.2	Bacilli	sufC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840		ko:K09013					ko00000,ko02000			iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710	Bacteria	1TQ98@1239,4HAD9@91061,COG0396@1,COG0396@2	NA|NA|NA	O	ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NHHNPPIF_00348	264199.stu0163	3e-183	647.9	Bacilli	tagO	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576	2.7.8.33,2.7.8.35	ko:K02851			R08856	RC00002	ko00000,ko01000,ko01003,ko01005				Bacteria	1TP9V@1239,4H9KT@91061,COG0472@1,COG0472@2	NA|NA|NA	M	transferase
NHHNPPIF_00349	322159.STER_0216	8.3e-134	483.0	Bacilli	mecA	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141		ko:K16511					ko00000				Bacteria	1UZ7D@1239,4HID6@91061,COG4862@1,COG4862@2	NA|NA|NA	NOT	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NHHNPPIF_00350	322159.STER_0215	9.1e-153	546.2	Bacilli	uppP	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031224,GO:0031226,GO:0042221,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050380,GO:0050896,GO:0071944	3.6.1.27	ko:K06153	ko00550,map00550		R05627	RC00002	ko00000,ko00001,ko01000,ko01011			iYL1228.KPN_03461	Bacteria	1TPFA@1239,4HB0M@91061,COG1968@1,COG1968@2	NA|NA|NA	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NHHNPPIF_00351	322159.STER_0214	1.8e-276	958.0	Bacilli	glnP			ko:K02029,ko:K02030,ko:K10040,ko:K17073,ko:K17074	ko02010,map02010	M00228,M00236,M00589			ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.20			Bacteria	1TPM3@1239,4HAS2@91061,COG0765@1,COG0765@2,COG0834@1,COG0834@2	NA|NA|NA	P	ABC transporter
NHHNPPIF_00352	264199.stu0158	1e-123	449.5	Bacilli	glnQ			ko:K17074,ko:K17076	ko02010,map02010	M00589			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.20			Bacteria	1TNYD@1239,4H9WY@91061,COG1126@1,COG1126@2	NA|NA|NA	E	abc transporter atp-binding protein
NHHNPPIF_00355	264199.stu0155	5e-94	350.5	Bacteria													Bacteria	COG4767@1,COG4767@2	NA|NA|NA	V	VanZ like family
NHHNPPIF_00356	264199.stu0154	9.2e-43	179.1	Bacilli	rpsO	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02956	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1VA5C@1239,4HKE9@91061,COG0184@1,COG0184@2	NA|NA|NA	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NHHNPPIF_00357	322159.STER_0207	7.9e-200	703.0	Bacilli	yhjX			ko:K03449,ko:K08177					ko00000,ko02000	2.A.1.11,2.A.1.17			Bacteria	1TSM5@1239,4HF98@91061,COG2807@1,COG2807@2	NA|NA|NA	P	Major Facilitator
NHHNPPIF_00358	322159.STER_0206	4.4e-112	410.6	Bacilli	fnr5												Bacteria	1V2AH@1239,4HFNC@91061,COG0664@1,COG0664@2	NA|NA|NA	K	Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NHHNPPIF_00359	264199.stu0151	1.2e-111	409.1	Bacilli	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.31,3.5.1.88	ko:K01450,ko:K01462	ko00270,ko00630,map00270,map00630		R00653	RC00165,RC00323	ko00000,ko00001,ko01000				Bacteria	1V5C6@1239,4HGUI@91061,COG0242@1,COG0242@2	NA|NA|NA	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NHHNPPIF_00360	322159.STER_0204	7.3e-236	822.8	Bacilli	ilvA	GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP22@1239,4H9NK@91061,COG1171@1,COG1171@2	NA|NA|NA	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NHHNPPIF_00361	435842.HMPREF0848_01478	7.7e-40	169.9	Bacilli	dex		3.2.1.11	ko:K05988	ko00500,map00500		R11309		ko00000,ko00001,ko01000		GH66		Bacteria	1TS2G@1239,4HF5J@91061,COG5297@1,COG5297@2	NA|NA|NA	G	Glycosyl hydrolase family 66
NHHNPPIF_00362	1046629.Ssal_02025	2.3e-18	97.4	Bacilli	dex		3.2.1.11	ko:K05988	ko00500,map00500		R11309		ko00000,ko00001,ko01000		GH66		Bacteria	1TS2G@1239,4HF5J@91061,COG5297@1,COG5297@2	NA|NA|NA	G	Glycosyl hydrolase family 66
NHHNPPIF_00363	1046629.Ssal_02025	3e-28	131.0	Bacilli	dex		3.2.1.11	ko:K05988	ko00500,map00500		R11309		ko00000,ko00001,ko01000		GH66		Bacteria	1TS2G@1239,4HF5J@91061,COG5297@1,COG5297@2	NA|NA|NA	G	Glycosyl hydrolase family 66
NHHNPPIF_00364	1046629.Ssal_02025	2e-08	64.3	Bacilli	dex		3.2.1.11	ko:K05988	ko00500,map00500		R11309		ko00000,ko00001,ko01000		GH66		Bacteria	1TS2G@1239,4HF5J@91061,COG5297@1,COG5297@2	NA|NA|NA	G	Glycosyl hydrolase family 66
NHHNPPIF_00365	264199.stu0146	3.3e-74	284.3	Bacilli	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360		ko:K07560					ko00000,ko01000,ko03016				Bacteria	1V6GH@1239,4HINN@91061,COG1490@1,COG1490@2	NA|NA|NA	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NHHNPPIF_00366	322159.STER_0200	0.0	1432.5	Bacilli	relA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657	2.7.6.5	ko:K00951	ko00230,map00230		R00429	RC00002,RC00078	ko00000,ko00001,ko01000			iHN637.CLJU_RS16615,iYO844.BSU27600	Bacteria	1TNYZ@1239,4HBX7@91061,COG0317@1,COG0317@2	NA|NA|NA	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NHHNPPIF_00367	264199.stu0144	5.3e-83	313.5	Bacilli	nrdI			ko:K03647					ko00000				Bacteria	1V71V@1239,4HIW7@91061,COG1780@1,COG1780@2	NA|NA|NA	F	Belongs to the NrdI family
NHHNPPIF_00368	322159.STER_0198	1e-241	842.4	Bacilli	cpdB	GO:0003674,GO:0003824,GO:0004112,GO:0005575,GO:0005623,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008252,GO:0008254,GO:0008663,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0030288,GO:0030313,GO:0031975,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0042597,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240		R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000			iEC55989_1330.EC55989_4773,iECH74115_1262.ECH74115_5730,iECNA114_1301.ECNA114_4436,iECSP_1301.ECSP_5315,iECW_1372.ECW_m4577,iECs_1301.ECs5191,iEKO11_1354.EKO11_4095,iEcE24377_1341.EcE24377A_4783,iG2583_1286.G2583_5043,iWFL_1372.ECW_m4577,iZ_1308.Z5824	Bacteria	1TPV2@1239,4HB9S@91061,COG0737@1,COG0737@2	NA|NA|NA	F	Belongs to the 5'-nucleotidase family
NHHNPPIF_00369	322159.STER_0198	1.5e-97	362.5	Bacilli	cpdB	GO:0003674,GO:0003824,GO:0004112,GO:0005575,GO:0005623,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008252,GO:0008254,GO:0008663,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0030288,GO:0030313,GO:0031975,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0042597,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240		R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000			iEC55989_1330.EC55989_4773,iECH74115_1262.ECH74115_5730,iECNA114_1301.ECNA114_4436,iECSP_1301.ECSP_5315,iECW_1372.ECW_m4577,iECs_1301.ECs5191,iEKO11_1354.EKO11_4095,iEcE24377_1341.EcE24377A_4783,iG2583_1286.G2583_5043,iWFL_1372.ECW_m4577,iZ_1308.Z5824	Bacteria	1TPV2@1239,4HB9S@91061,COG0737@1,COG0737@2	NA|NA|NA	F	Belongs to the 5'-nucleotidase family
NHHNPPIF_00370	322159.STER_0198	1.5e-35	156.0	Bacilli	cpdB	GO:0003674,GO:0003824,GO:0004112,GO:0005575,GO:0005623,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008252,GO:0008254,GO:0008663,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0030288,GO:0030313,GO:0031975,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0042597,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240		R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000			iEC55989_1330.EC55989_4773,iECH74115_1262.ECH74115_5730,iECNA114_1301.ECNA114_4436,iECSP_1301.ECSP_5315,iECW_1372.ECW_m4577,iECs_1301.ECs5191,iEKO11_1354.EKO11_4095,iEcE24377_1341.EcE24377A_4783,iG2583_1286.G2583_5043,iWFL_1372.ECW_m4577,iZ_1308.Z5824	Bacteria	1TPV2@1239,4HB9S@91061,COG0737@1,COG0737@2	NA|NA|NA	F	Belongs to the 5'-nucleotidase family
NHHNPPIF_00371	322159.STER_0197	3.7e-134	484.2	Bacilli	rsmE	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761					ko00000,ko01000,ko03009				Bacteria	1V1CT@1239,4HH8P@91061,COG1385@1,COG1385@2	NA|NA|NA	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NHHNPPIF_00372	264199.stu0137	1.3e-176	625.5	Bacilli	prmA			ko:K02687					ko00000,ko01000,ko03009				Bacteria	1TPKI@1239,4HAMF@91061,COG2264@1,COG2264@2	NA|NA|NA	J	Ribosomal protein L11 methyltransferase
NHHNPPIF_00373	322159.STER_0195	7.3e-39	166.0	Bacilli	mutT3		3.6.1.13,3.6.1.55	ko:K01515,ko:K03574	ko00230,map00230		R01054	RC00002	ko00000,ko00001,ko01000,ko03400				Bacteria	1V8D5@1239,4HJKW@91061,COG0494@1,COG0494@2	NA|NA|NA	L	NUDIX domain
NHHNPPIF_00374	862969.SCI_0845	1.7e-167	595.9	Streptococcus anginosus group													Bacteria	1TSXI@1239,42E4Z@671232,4I4BM@91061,COG1961@1,COG1961@2	NA|NA|NA	L	Recombinase
NHHNPPIF_00375	1154860.SAG0136_01735	1.8e-189	669.1	Firmicutes													Bacteria	1TQ8Y@1239,COG1961@1,COG1961@2	NA|NA|NA	L	Resolvase, N-terminal domain protein
NHHNPPIF_00376	1154860.SAG0136_01740	9.2e-236	822.8	Firmicutes													Bacteria	1TPA6@1239,COG1961@1,COG1961@2	NA|NA|NA	L	Psort location Cytoplasmic, score
NHHNPPIF_00378	1154860.SAG0136_11560	6.1e-19	100.5	Firmicutes													Bacteria	1V1GF@1239,COG1191@1,COG1191@2	NA|NA|NA	K	Psort location Cytoplasmic, score
NHHNPPIF_00380	996306.SSUR61_1652	5.1e-77	294.3	Bacilli				ko:K07052					ko00000				Bacteria	1VFRX@1239,4HPZB@91061,COG1266@1,COG1266@2	NA|NA|NA	S	CAAX protease self-immunity
NHHNPPIF_00381	996306.SSUR61_0113	1.2e-47	197.2	Bacilli	blpT												Bacteria	1W6SH@1239,2DWQH@1,341F6@2,4HX74@91061	NA|NA|NA		
NHHNPPIF_00382	1123298.KB904062_gene930	9.3e-75	286.2	Bacilli				ko:K07497					ko00000				Bacteria	1TQQY@1239,4HC8M@91061,COG2801@1,COG2801@2	NA|NA|NA	L	Transposase and inactivated derivatives
NHHNPPIF_00383	862970.SAIN_0559	4.1e-33	147.5	Streptococcus anginosus group				ko:K07497					ko00000				Bacteria	1TQQY@1239,42E57@671232,4HC8M@91061,COG2801@1,COG2801@2	NA|NA|NA	L	Integrase core domain
NHHNPPIF_00384	1123303.AQVD01000001_gene559	1.4e-75	289.3	Bacteria				ko:K07483					ko00000				Bacteria	COG2963@1,COG2963@2	NA|NA|NA	L	transposase activity
NHHNPPIF_00386	40041.SZO_04310	1.6e-12	78.6	Bacilli													Bacteria	1W3RP@1239,2DZ2R@1,34C7V@2,4HZZT@91061	NA|NA|NA	S	Bacteriocin class II with double-glycine leader peptide
NHHNPPIF_00387	1005704.HMPREF9968_1217	4.3e-18	96.7	Streptococcus oralis	comA			ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024				ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.21			Bacteria	1V77J@1239,1WNWP@1303,4HAX2@91061,COG2274@1,COG2274@2	NA|NA|NA	V	Papain-like cysteine protease AvrRpt2
NHHNPPIF_00388	1123304.AQYA01000033_gene1929	0.0	1134.8	Bacilli	comA			ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024				ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.21			Bacteria	1V77J@1239,4HAX2@91061,COG2274@1,COG2274@2	NA|NA|NA	V	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NHHNPPIF_00389	759913.SDSE_0544	1.3e-145	523.1	Streptococcus dysgalactiae group	mesE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K20345	ko02024,map02024				ko00000,ko00001,ko02000	3.A.1.112,8.A.1			Bacteria	1M9WQ@119603,1V5C8@1239,4HHKB@91061,COG0845@1,COG0845@2	NA|NA|NA	M	HlyD family secretion protein
NHHNPPIF_00391	1336234.JAGN01000013_gene191	4.5e-122	444.9	Carnobacteriaceae	blpH		2.7.13.3	ko:K07706	ko02020,ko02024,map02020,map02024	M00495			ko00000,ko00001,ko00002,ko01000,ko01001,ko02022				Bacteria	1UYTM@1239,27HJV@186828,4I3H2@91061,COG3290@1,COG3290@2	NA|NA|NA	T	GHKL domain
NHHNPPIF_00392	1321372.AQQB01000055_gene1644	2.6e-103	381.7	Streptococcus suis	blpR			ko:K07707	ko02020,ko02024,map02020,map02024	M00495			ko00000,ko00001,ko00002,ko02022				Bacteria	1U92Z@1239,1WTMJ@1307,4IJ3N@91061,COG3279@1,COG3279@2	NA|NA|NA	KT	LytTr DNA-binding domain
NHHNPPIF_00393	1297534.CAUJ01000007_gene1490	3.3e-21	107.8	Bacteria	blpS												Bacteria	COG3279@1,COG3279@2	NA|NA|NA	KT	phosphorelay signal transduction system
NHHNPPIF_00394	862967.SIR_1156	1.2e-19	102.8	Streptococcus anginosus group													Bacteria	1TVNN@1239,2CM4R@1,303ZT@2,42DKI@671232,4I3R0@91061	NA|NA|NA		
NHHNPPIF_00395	1154860.SAG0136_01820	4.1e-299	1033.5	Bacilli													Bacteria	1V2SB@1239,4HFEX@91061,COG3843@1,COG3843@2	NA|NA|NA	U	relaxase
NHHNPPIF_00396	996306.SSUR61_1123	2.1e-50	204.9	Streptococcus suis													Bacteria	1U93J@1239,1WTP2@1307,2BFHJ@1,329BC@2,4IJ4C@91061	NA|NA|NA	S	Bacterial mobilisation protein (MobC)
NHHNPPIF_00397	996306.SSUR61_1124	1.7e-52	211.8	Streptococcus suis													Bacteria	1W52Y@1239,1WTSJ@1307,2BWBR@1,2ZDFR@2,4I0XT@91061	NA|NA|NA		
NHHNPPIF_00398	158189.SpiBuddy_2398	8.9e-49	200.7	Bacteria													Bacteria	COG1715@1,COG1715@2	NA|NA|NA	V	Restriction endonuclease
NHHNPPIF_00399	525254.HMPREF0072_2204	2.3e-190	672.9	Clostridia	vrlS												Bacteria	1U9TG@1239,25FHQ@186801,COG1204@1,COG1204@2	NA|NA|NA	L	DEAD DEAH box helicase
NHHNPPIF_00400	1408445.JHXP01000009_gene2758	5.8e-40	171.4	Gammaproteobacteria	vrlR												Bacteria	1RAX0@1224,1S35B@1236,2C2MI@1,2ZBMN@2	NA|NA|NA	S	Domain of unknown function (DUF1837)
NHHNPPIF_00401	482234.SCAZ3_06005	2.6e-130	471.5	Bacilli			2.7.1.176	ko:K07452,ko:K16214					ko00000,ko01000,ko02048				Bacteria	1V4WZ@1239,4HKUZ@91061,COG0542@1,COG0542@2	NA|NA|NA	O	Zeta toxin
NHHNPPIF_00402	1214166.ALLG01000002_gene1720	1.1e-281	975.7	Streptococcus suis													Bacteria	1TPFS@1239,1WTYV@1307,4H9V9@91061,COG3039@1,COG3039@2	NA|NA|NA	L	Transposase DDE domain
NHHNPPIF_00403	391295.SSU05_0938	2.3e-39	167.9	Streptococcus suis													Bacteria	1U93B@1239,1WTNM@1307,2BV34@1,32QG3@2,4IJ43@91061	NA|NA|NA		
NHHNPPIF_00404	1214166.ALLG01000025_gene1206	2.9e-58	231.1	Streptococcus suis	XK27_10880												Bacteria	1U91T@1239,1WTG8@1307,2AMA9@1,31C58@2,4IJ22@91061	NA|NA|NA		
NHHNPPIF_00405	1214166.ALLG01000025_gene1207	1.1e-17	95.5	Streptococcus suis	XK27_10875												Bacteria	1U946@1239,1WTQH@1307,2BFJD@1,329DD@2,4IJ55@91061	NA|NA|NA		
NHHNPPIF_00406	1214217.ALNF01000037_gene354	1.3e-149	535.8	Streptococcus suis				ko:K02316	ko03030,map03030				ko00000,ko00001,ko01000,ko03032				Bacteria	1TRTK@1239,1WT2U@1307,4HK3Y@91061,COG0358@1,COG0358@2	NA|NA|NA	L	Toprim-like
NHHNPPIF_00407	1154860.SAG0136_11645	2.7e-11	73.9	Bacilli				ko:K02316	ko03030,map03030				ko00000,ko00001,ko01000,ko03032				Bacteria	1TRTK@1239,4HK3Y@91061,COG0358@1,COG0358@2	NA|NA|NA	L	Protein of unknown function (DUF3991)
NHHNPPIF_00408	663952.SDD27957_05275	9.9e-104	382.9	Bacteria	XK27_10865												Bacteria	2DCG5@1,2ZE0K@2	NA|NA|NA		
NHHNPPIF_00409	1302863.I872_10315	3.5e-18	99.8	Bacteria				ko:K07451					ko00000,ko01000,ko02048				Bacteria	COG1403@1,COG1403@2	NA|NA|NA	V	endonuclease activity
NHHNPPIF_00410	1302863.I872_10320	5.3e-45	189.1	Bacteria													Bacteria	COG3593@1,COG3593@2	NA|NA|NA	L	DNA synthesis involved in DNA repair
NHHNPPIF_00411	1214217.ALNF01000037_gene359	2.3e-31	141.4	Streptococcus suis													Bacteria	1U94C@1239,1WTR0@1307,2AMFB@1,31CAV@2,4IJ5B@91061	NA|NA|NA		
NHHNPPIF_00412	996306.SSUR61_1133	2.4e-44	184.5	Streptococcus suis													Bacteria	1U93N@1239,1WTP6@1307,29R24@1,30C38@2,4IJ4F@91061	NA|NA|NA		
NHHNPPIF_00413	1214166.ALLG01000025_gene1222	8.1e-241	839.3	Streptococcus suis	XK27_00500												Bacteria	1TPQA@1239,1WSVK@1307,4HDHN@91061,COG0553@1,COG0553@2,COG0827@1,COG0827@2,COG4646@1,COG4646@2	NA|NA|NA	L	SNF2 family N-terminal domain
NHHNPPIF_00414	1154860.SAG0136_11725	0.0	1177.2	Bacilli													Bacteria	1TP9A@1239,4H9NW@91061,COG3344@1,COG3344@2	NA|NA|NA	L	reverse transcriptase
NHHNPPIF_00415	391295.SSU05_0962	0.0	3371.6	Streptococcus suis	XK27_00500												Bacteria	1TPQA@1239,1WSVK@1307,4HDHN@91061,COG0553@1,COG0553@2,COG0827@1,COG0827@2,COG4646@1,COG4646@2	NA|NA|NA	L	SNF2 family N-terminal domain
NHHNPPIF_00416	996306.SSUR61_1139	7.8e-89	333.2	Streptococcus suis	XK27_00505												Bacteria	1U906@1239,1WT7S@1307,2BQP9@1,32JJP@2,4IJ00@91061	NA|NA|NA		
NHHNPPIF_00417	996306.SSUR61_1140	5.1e-11	73.2	Streptococcus suis	XK27_00510												Bacteria	1U94D@1239,1WTR2@1307,29R2E@1,30C3I@2,4IJ5D@91061	NA|NA|NA		
NHHNPPIF_00418	1123315.AUIP01000021_gene2251	0.0	2852.0	Bacilli	XK27_00515												Bacteria	1TSVF@1239,4HGKU@91061,COG3087@1,COG3087@2	NA|NA|NA	D	Glucan-binding protein C
NHHNPPIF_00419	1123314.AUIO01000002_gene1898	6.8e-107	393.3	Bacilli	abiGI												Bacteria	1V8GF@1239,4IQTV@91061,COG5340@1,COG5340@2	NA|NA|NA	K	Transcriptional regulator, AbiEi antitoxin
NHHNPPIF_00420	1123315.AUIP01000021_gene2249	6e-149	533.5	Bacilli													Bacteria	1TSFX@1239,4HGAF@91061,COG2253@1,COG2253@2	NA|NA|NA	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system
NHHNPPIF_00421	1214217.ALNF01000037_gene383	0.0	1617.8	Streptococcus suis	XK27_00530												Bacteria	1VPFZ@1239,1WSSZ@1307,4HFGV@91061,COG3942@1,COG3942@2	NA|NA|NA	S	CHAP domain
NHHNPPIF_00422	996306.SSUR61_1147	0.0	1467.2	Streptococcus suis													Bacteria	1TPDR@1239,1WSV1@1307,4HUB9@91061,COG3451@1,COG3451@2	NA|NA|NA	U	'COG3451 Type IV secretory pathway, VirB4 components'
NHHNPPIF_00423	1214217.ALNF01000064_gene2075	1.5e-61	241.9	Streptococcus suis	XK27_00550												Bacteria	1U92M@1239,1WTK7@1307,2AMBF@1,31C6I@2,4IJ34@91061	NA|NA|NA	S	PrgI family protein
NHHNPPIF_00424	910313.HMPREF9320_1729	2.6e-139	501.5	Bacilli													Bacteria	1VY42@1239,2EFFF@1,33986@2,4HMPN@91061	NA|NA|NA		
NHHNPPIF_00425	1214166.ALLG01000025_gene1233	9.2e-34	149.1	Streptococcus suis	XK27_00560												Bacteria	1W4XR@1239,1WTPF@1307,295KB@1,2ZSXU@2,4I17I@91061	NA|NA|NA		
NHHNPPIF_00426	391295.SSU05_0973	0.0	1203.7	Streptococcus suis	traG			ko:K03205	ko03070,map03070	M00333			ko00000,ko00001,ko00002,ko02044	3.A.7			Bacteria	1UAJF@1239,1WT6H@1307,4IPX4@91061,COG3505@1,COG3505@2	NA|NA|NA	U	Type IV secretory system Conjugative DNA transfer
NHHNPPIF_00427	1214166.ALLG01000025_gene1235	1.3e-79	302.4	Streptococcus suis	XK27_00570												Bacteria	1U8XR@1239,1WSKJ@1307,29QYR@1,30BZR@2,4IIWI@91061	NA|NA|NA		
NHHNPPIF_00428	996306.SSUR61_1153	1e-91	342.8	Streptococcus suis	ypbD			ko:K07052					ko00000				Bacteria	1W5XP@1239,1WSW7@1307,4I0RW@91061,COG1266@1,COG1266@2	NA|NA|NA	S	CAAX protease self-immunity
NHHNPPIF_00429	996306.SSUR61_1154	1.5e-36	158.3	Streptococcus suis	XK27_00580												Bacteria	1U945@1239,1WTQF@1307,2AMF1@1,31CAH@2,4IJ54@91061	NA|NA|NA		
NHHNPPIF_00430	1214166.ALLG01000025_gene1238	1e-63	249.2	Streptococcus suis	XK27_00585												Bacteria	1U91V@1239,1WTGJ@1307,30C2H@2,4IJ24@91061,COG1393@1	NA|NA|NA	P	arsenate reductase (glutaredoxin) activity
NHHNPPIF_00431	1214166.ALLG01000025_gene1239	1.4e-74	285.4	Streptococcus suis	XK27_00590												Bacteria	1W4PT@1239,1WTD4@1307,2EV5A@1,33NK4@2,4IJ1G@91061	NA|NA|NA		
NHHNPPIF_00432	1154860.SAG0136_10340	3.3e-258	897.1	Bacilli	hpaIIM		2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036				Bacteria	1TPNE@1239,4HB9C@91061,COG0270@1,COG0270@2	NA|NA|NA	H	cytosine-specific methyltransferase
NHHNPPIF_00433	1214217.ALNF01000064_gene2086	5.8e-141	506.9	Streptococcus suis	repA												Bacteria	1VHQA@1239,1WSPT@1307,2DP1C@1,3304N@2,4HPY6@91061	NA|NA|NA	S	Replication initiator protein A (RepA) N-terminus
NHHNPPIF_00434	996306.SSUR61_1159	5.2e-20	102.8	Streptococcus suis													Bacteria	1U94R@1239,1WTRT@1307,2AMGJ@1,31CC5@2,4IJ5U@91061	NA|NA|NA		
NHHNPPIF_00435	264199.stu0136	3.4e-19	100.1	Bacilli	mutT3		3.6.1.13,3.6.1.55	ko:K01515,ko:K03574	ko00230,map00230		R01054	RC00002	ko00000,ko00001,ko01000,ko03400				Bacteria	1V8D5@1239,4HJKW@91061,COG0494@1,COG0494@2	NA|NA|NA	L	NUDIX domain
NHHNPPIF_00436	264199.stu0135	4.2e-83	313.9	Bacilli	XK27_03960												Bacteria	1VFZQ@1239,2E0MY@1,32W75@2,4HKWR@91061	NA|NA|NA	S	Protein of unknown function (DUF3013)
NHHNPPIF_00437	264199.stu0134	7.6e-310	1068.9	Bacilli	pyrG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000			iHN637.CLJU_RS01075,iNJ661.Rv1699	Bacteria	1TP34@1239,4H9X6@91061,COG0504@1,COG0504@2	NA|NA|NA	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NHHNPPIF_00438	322159.STER_0192	4.8e-73	280.8	Bacilli	rpoE	GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576		ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko03021,ko03400				Bacteria	1V6WX@1239,4HIUK@91061,COG3343@1,COG3343@2	NA|NA|NA	K	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NHHNPPIF_00439	322159.STER_0191	6.4e-219	766.5	Bacilli	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464		ko:K03545					ko00000				Bacteria	1TQQ8@1239,4H9Q8@91061,COG0544@1,COG0544@2	NA|NA|NA	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NHHNPPIF_00440	264199.stu0131	1.6e-146	525.4	Bacilli	ykuT	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0042802,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004		ko:K22044					ko00000,ko02000	1.A.23.3			Bacteria	1TR9Z@1239,4HCB8@91061,COG0668@1,COG0668@2	NA|NA|NA	M	mechanosensitive ion channel
NHHNPPIF_00441	1046629.Ssal_02044	1.6e-77	295.4	Bacteria	sigH			ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024				ko00000,ko00001,ko03000,ko03021				Bacteria	COG1595@1,COG1595@2	NA|NA|NA	K	DNA-templated transcription, initiation
NHHNPPIF_00442	435842.HMPREF0848_00449	2e-31	141.4	Firmicutes	XK27_08085												Bacteria	1VM50@1239,2EJUK@1,33DJ8@2	NA|NA|NA		
NHHNPPIF_00443	322159.STER_1210	8.4e-88	329.7	Bacilli	XK27_08080		3.1.1.53	ko:K05970					ko00000,ko01000				Bacteria	1TR6Z@1239,4HGB0@91061,COG4632@1,COG4632@2	NA|NA|NA	G	Exopolysaccharide biosynthesis protein
NHHNPPIF_00444	1046629.Ssal_01327	7.9e-10	69.3	Bacilli	XK27_08080		3.1.1.53	ko:K05970					ko00000,ko01000				Bacteria	1TR6Z@1239,4HGB0@91061,COG4632@1,COG4632@2	NA|NA|NA	G	Exopolysaccharide biosynthesis protein
NHHNPPIF_00445	322159.STER_1212	5.8e-140	503.4	Bacilli	hisK		3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	1V77D@1239,4HGYX@91061,COG1387@1,COG1387@2	NA|NA|NA	E	Histidinol phosphatase and related hydrolases of the PHP family
NHHNPPIF_00446	322159.STER_1213	5.8e-120	436.8	Bacilli	ylfI												Bacteria	1VGZ1@1239,4HNTM@91061,COG4478@1,COG4478@2	NA|NA|NA	S	tigr01906
NHHNPPIF_00447	322159.STER_1214	5.9e-143	513.5	Bacilli	nagD		2.7.1.25,3.1.3.41	ko:K00860,ko:K01101	ko00230,ko00627,ko00920,ko01100,ko01120,map00230,map00627,map00920,map01100,map01120	M00176	R00509,R03024,R04928	RC00002,RC00078,RC00151	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQGM@1239,4HA3R@91061,COG0647@1,COG0647@2	NA|NA|NA	G	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NHHNPPIF_00448	264199.stu1235	5.7e-143	513.5	Bacilli	fat		3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100		R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004				Bacteria	1V3RB@1239,4HHJ4@91061,COG3884@1,COG3884@2	NA|NA|NA	I	Acyl-ACP thioesterase
NHHNPPIF_00449	264199.stu1236	6.9e-217	759.6	Bacilli	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576											Bacteria	1TPES@1239,4HA60@91061,COG0635@1,COG0635@2	NA|NA|NA	H	Involved in the biosynthesis of porphyrin-containing compound
NHHNPPIF_00450	1116231.SMA_1913	4.6e-18	97.1	Bacilli				ko:K07497					ko00000				Bacteria	1TU21@1239,4HDK4@91061,COG2801@1,COG2801@2	NA|NA|NA	L	COG2801 Transposase and inactivated derivatives
NHHNPPIF_00451	467705.SGO_1359	1.6e-112	412.5	Bacteria				ko:K20373	ko02024,map02024				ko00000,ko00001,ko03000				Bacteria	COG1396@1,COG1396@2	NA|NA|NA	K	sequence-specific DNA binding
NHHNPPIF_00452	264199.stu1512	2e-11	74.7	Bacilli				ko:K06871					ko00000				Bacteria	1TQPS@1239,4HCKJ@91061,COG0641@1,COG0641@2	NA|NA|NA	C	Arylsulfatase regulator (Fe-S oxidoreductase)
NHHNPPIF_00455	264199.stu1389	3.5e-106	391.0	Bacilli	MA20_06410												Bacteria	1TRUX@1239,4HFB2@91061,COG1280@1,COG1280@2	NA|NA|NA	E	LysE type translocator
NHHNPPIF_00456	491916.RHECIAT_PC0000880	8.6e-70	270.8	Rhizobiaceae													Bacteria	1N5JR@1224,2VGXQ@28211,4BNNM@82115,COG0318@1,COG0318@2	NA|NA|NA	IQ	PFAM AMP-dependent synthetase and ligase
NHHNPPIF_00457	322159.STER_1519	1.6e-233	815.1	Bacilli	murA	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100		R00660	RC00350	ko00000,ko00001,ko01000,ko01011			iYO844.BSU37100	Bacteria	1TPAU@1239,4H9KI@91061,COG0766@1,COG0766@2	NA|NA|NA	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHHNPPIF_00458	322159.STER_1520	0.0	1456.0	Bacilli	comEC			ko:K02238		M00429			ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2			Bacteria	1TS9U@1239,4H9M4@91061,COG0658@1,COG0658@2,COG2333@1,COG2333@2	NA|NA|NA	S	Competence protein ComEC
NHHNPPIF_00459	322159.STER_1521	3e-98	364.8	Bacilli	comEA			ko:K02237		M00429			ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2			Bacteria	1VA3W@1239,4HKJ1@91061,COG1555@1,COG1555@2	NA|NA|NA	L	COG1555 DNA uptake protein and related DNA-binding proteins
NHHNPPIF_00460	322159.STER_1522	1.7e-142	511.9	Bacilli	plsC	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008374,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0042171,GO:0044464,GO:0071617,GO:0071944	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	1U8N2@1239,4HDQR@91061,COG0204@1,COG0204@2	NA|NA|NA	I	Acyltransferase
NHHNPPIF_00461	435842.HMPREF0848_01183	1.8e-140	505.4	Bacilli	nodB3												Bacteria	1TYRH@1239,4HHQN@91061,COG0726@1,COG0726@2	NA|NA|NA	G	deacetylase
NHHNPPIF_00462	322159.STER_1524	7.1e-141	506.5	Bacilli	yabB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.223	ko:K07461,ko:K15460					ko00000,ko01000,ko03016				Bacteria	1TQ25@1239,4HA8W@91061,COG4123@1,COG4123@2	NA|NA|NA	L	Methyltransferase
NHHNPPIF_00463	264199.stu1567	1e-41	175.6	Bacilli	yazA			ko:K07461					ko00000				Bacteria	1VEZF@1239,4HNHJ@91061,COG2827@1,COG2827@2	NA|NA|NA	L	endonuclease containing a URI domain
NHHNPPIF_00464	322159.STER_1526	6.9e-223	780.0	Bacilli	cshA	GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363	3.6.4.13	ko:K05592,ko:K18692	ko03018,map03018				ko00000,ko00001,ko01000,ko03009,ko03019				Bacteria	1TPAP@1239,4HAB3@91061,COG0513@1,COG0513@2	NA|NA|NA	JKL	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NHHNPPIF_00465	264199.stu1569	1.5e-153	548.9	Bacilli	corA			ko:K03284					ko00000,ko02000	1.A.35.1,1.A.35.3			Bacteria	1TPI8@1239,4HCQ6@91061,COG0598@1,COG0598@2	NA|NA|NA	P	CorA-like protein
NHHNPPIF_00466	264199.stu1570	2.5e-62	244.6	Bacilli	yjqA												Bacteria	1V77G@1239,3172B@2,4HJ0W@91061,arCOG12631@1	NA|NA|NA	S	Bacterial PH domain
NHHNPPIF_00467	322159.STER_1529	2.3e-99	368.2	Bacilli	thiT			ko:K16789					ko00000,ko02000	2.A.88.3			Bacteria	1V6YE@1239,4HIJE@91061,COG3859@1,COG3859@2	NA|NA|NA	S	Thiamine transporter
NHHNPPIF_00468	264199.stu0035	1.4e-292	1011.5	Bacilli	purH	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147			iJN678.purH	Bacteria	1TPQ5@1239,4H9YY@91061,COG0138@1,COG0138@2	NA|NA|NA	F	Bifunctional purine biosynthesis protein PurH
NHHNPPIF_00469	264199.stu0034	5.2e-101	373.6	Bacilli	purN		2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000				Bacteria	1V3RJ@1239,4HGY5@91061,COG0299@1,COG0299@2	NA|NA|NA	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NHHNPPIF_00470	904306.HMPREF9192_0010	3.6e-188	664.1	Bacilli	purM	GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.1,6.3.4.13	ko:K01933,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04208	RC00090,RC00166,RC01100	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_1844,iECSF_1327.ECSF_2340	Bacteria	1TP9J@1239,4HABW@91061,COG0150@1,COG0150@2	NA|NA|NA	F	Phosphoribosylformylglycinamidine cyclo-ligase
NHHNPPIF_00471	435842.HMPREF0848_01956	8.6e-273	945.7	Bacilli	purF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002			iSB619.SA_RS05225	Bacteria	1TPH3@1239,4HAXU@91061,COG0034@1,COG0034@2	NA|NA|NA	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NHHNPPIF_00472	264199.stu0031	0.0	2408.6	Bacilli	purL		6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPAS@1239,4HB3N@91061,COG0046@1,COG0046@2,COG0047@1,COG0047@2	NA|NA|NA	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHHNPPIF_00473	264199.stu0030	4.4e-129	467.2	Bacilli	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016881,GO:0044424,GO:0044444,GO:0044464	4.1.1.21,4.3.2.2,6.3.2.6	ko:K01587,ko:K01756,ko:K01923	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04209,R04559,R04591	RC00064,RC00162,RC00379,RC00444,RC00445,RC00590	ko00000,ko00001,ko00002,ko01000			iAF1260.b2476,iB21_1397.B21_02330,iBWG_1329.BWG_2240,iE2348C_1286.E2348C_2713,iEC042_1314.EC042_2677,iEC55989_1330.EC55989_2759,iECABU_c1320.ECABU_c27880,iECBD_1354.ECBD_1213,iECB_1328.ECB_02368,iECDH10B_1368.ECDH10B_2642,iECDH1ME8569_1439.ECDH1ME8569_2402,iECDH1ME8569_1439.EcDH1_1193,iECD_1391.ECD_02368,iECED1_1282.ECED1_2911,iECH74115_1262.ECH74115_3698,iECIAI1_1343.ECIAI1_2527,iECNA114_1301.ECNA114_2561,iECO103_1326.ECO103_2988,iECO111_1330.ECO111_3199,iECO26_1355.ECO26_3522,iECOK1_1307.ECOK1_2784,iECP_1309.ECP_2490,iECS88_1305.ECS88_2658,iECSE_1348.ECSE_2760,iECSF_1327.ECSF_2329,iECSP_1301.ECSP_3415,iECUMN_1333.ECUMN_2789,iECW_1372.ECW_m2698,iECs_1301.ECs3338,iEKO11_1354.EKO11_1259,iETEC_1333.ETEC_2581,iEcDH1_1363.EcDH1_1193,iEcE24377_1341.EcE24377A_2757,iEcHS_1320.EcHS_A2607,iEcSMS35_1347.EcSMS35_2623,iEcolC_1368.EcolC_1200,iG2583_1286.G2583_2999,iJN746.PP_1240,iJO1366.b2476,iJR904.b2476,iLF82_1304.LF82_1775,iNRG857_1313.NRG857_12360,iSFV_1184.SFV_2521,iSF_1195.SF2519,iSFxv_1172.SFxv_2773,iS_1188.S2669,iSbBS512_1146.SbBS512_E2848,iUMNK88_1353.UMNK88_3071,iWFL_1372.ECW_m2698,iY75_1357.Y75_RS12925,iYL1228.KPN_02810,iZ_1308.Z3735	Bacteria	1TP11@1239,4H9U8@91061,COG0152@1,COG0152@2	NA|NA|NA	F	Belongs to the SAICAR synthetase family
NHHNPPIF_00474	322159.STER_0048	4.2e-34	150.2	Bacteria	acpP1			ko:K02078					ko00000,ko00001				Bacteria	COG0236@1,COG0236@2	NA|NA|NA	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHHNPPIF_00475	322159.STER_0047	2.5e-178	631.3	Bacilli	plsX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	1TPXS@1239,4HA0R@91061,COG0416@1,COG0416@2	NA|NA|NA	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NHHNPPIF_00476	322159.STER_0046	1e-142	512.7	Bacilli	recO	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360		ko:K03584	ko03440,map03440				ko00000,ko00001,ko03400				Bacteria	1UZ19@1239,4HAHI@91061,COG1381@1,COG1381@2	NA|NA|NA	L	Involved in DNA repair and RecF pathway recombination
NHHNPPIF_00477	264199.stu0026	5.5e-217	760.0	Bacilli	araT		2.6.1.1	ko:K00812,ko:K00841,ko:K10907	ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	M00525	R00355,R00694,R00734,R00896,R02433,R02619,R04467,R05052	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	1TP0J@1239,4HA13@91061,COG0436@1,COG0436@2	NA|NA|NA	E	Aminotransferase
NHHNPPIF_00478	264199.stu0025	7.3e-26	122.5	Bacteria													Bacteria	COG3464@1,COG3464@2	NA|NA|NA		
NHHNPPIF_00479	264199.stu0023	4.3e-175	620.5	Bacilli	prs		2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_2848	Bacteria	1TQ6Q@1239,4HB61@91061,COG0462@1,COG0462@2	NA|NA|NA	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHHNPPIF_00480	322159.STER_0042	4.1e-59	233.8	Bacilli	usp		3.5.1.28	ko:K21471,ko:K22409					ko00000,ko01000,ko01002,ko01011		CBM50		Bacteria	1VCXB@1239,4IS6H@91061,COG3883@1,COG3883@2,COG3942@1,COG3942@2	NA|NA|NA	S	CHAP domain
NHHNPPIF_00481	264199.stu0370	2.4e-90	338.2	Bacilli	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113		ko:K05808					ko00000,ko03009				Bacteria	1V1D5@1239,4HFX9@91061,COG1544@1,COG1544@2	NA|NA|NA	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NHHNPPIF_00482	264199.stu0369	4.9e-122	443.7	Bacilli	comFC			ko:K02242		M00429			ko00000,ko00002,ko02044				Bacteria	1V73S@1239,4HJ6R@91061,COG1040@1,COG1040@2	NA|NA|NA	S	Competence protein
NHHNPPIF_00483	322159.STER_0406	2e-252	877.9	Bacilli	comFA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576		ko:K02240		M00429			ko00000,ko00002,ko02044	3.A.11.1			Bacteria	1TPZE@1239,4HB00@91061,COG4098@1,COG4098@2	NA|NA|NA	L	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NHHNPPIF_00484	322159.STER_0405	6.3e-111	406.8	Bacilli	yvyE		3.4.13.9	ko:K01271					ko00000,ko01000,ko01002				Bacteria	1V6MQ@1239,4HBIT@91061,COG1739@1,COG1739@2	NA|NA|NA	S	YigZ family
NHHNPPIF_00485	264199.stu0366	4.9e-168	597.0	Bacilli	cysK	GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP30@1239,4HAMU@91061,COG0031@1,COG0031@2	NA|NA|NA	E	Belongs to the cysteine synthase cystathionine beta- synthase family
NHHNPPIF_00486	264199.stu0365	9.3e-42	176.0	Bacteria	acuB			ko:K04767					ko00000				Bacteria	COG0517@1,COG0517@2	NA|NA|NA	S	IMP dehydrogenase activity
NHHNPPIF_00487	1046629.Ssal_01826	1e-39	169.1	Bacilli	acuB			ko:K04767					ko00000				Bacteria	1V4CD@1239,4HGX4@91061,COG0517@1,COG0517@2	NA|NA|NA	S	CBS domain
NHHNPPIF_00488	1046629.Ssal_01828	4.8e-123	447.2	Bacilli	livF			ko:K01996	ko02010,ko02024,map02010,map02024	M00237			ko00000,ko00001,ko00002,ko02000	3.A.1.4			Bacteria	1TPW4@1239,4HABJ@91061,COG0410@1,COG0410@2	NA|NA|NA	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
NHHNPPIF_00489	322159.STER_0401	6.2e-137	493.4	Bacilli	livG			ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237			ko00000,ko00001,ko00002,ko02000	3.A.1.4			Bacteria	1TR0P@1239,4HASG@91061,COG0411@1,COG0411@2	NA|NA|NA	E	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
NHHNPPIF_00490	264199.stu0361	1.4e-138	499.2	Bacilli	livM			ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237			ko00000,ko00001,ko00002,ko02000	3.A.1.4			Bacteria	1TPMZ@1239,4HDIU@91061,COG4177@1,COG4177@2	NA|NA|NA	E	Belongs to the binding-protein-dependent transport system permease family
NHHNPPIF_00491	264199.stu0360	1.9e-145	521.9	Bacilli	livH			ko:K01997	ko02010,ko02024,map02010,map02024	M00237			ko00000,ko00001,ko00002,ko02000	3.A.1.4			Bacteria	1TR24@1239,4HBFZ@91061,COG0559@1,COG0559@2	NA|NA|NA	E	Belongs to the binding-protein-dependent transport system permease family
NHHNPPIF_00492	264199.stu0359	9.1e-212	742.7	Bacilli	livJ			ko:K01999	ko02010,ko02024,map02010,map02024	M00237			ko00000,ko00001,ko00002,ko02000	3.A.1.4			Bacteria	1TPQ2@1239,4H9PI@91061,COG0683@1,COG0683@2	NA|NA|NA	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
NHHNPPIF_00493	264199.stu0358	7.1e-46	189.5	Bacilli	ylbG												Bacteria	1VF52@1239,4HNTH@91061,COG4471@1,COG4471@2	NA|NA|NA	S	UPF0298 protein
NHHNPPIF_00494	264199.stu0357	1.3e-73	282.3	Bacilli	ylbF												Bacteria	1V3R6@1239,4HGYS@91061,COG3679@1,COG3679@2	NA|NA|NA	S	Belongs to the UPF0342 family
NHHNPPIF_00495	264199.stu0356	8.3e-105	386.3	Bacilli	clpP	GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212				ko00000,ko00001,ko01000,ko01002				Bacteria	1TQ91@1239,4HA8J@91061,COG0740@1,COG0740@2	NA|NA|NA	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NHHNPPIF_00496	264199.stu0355	4.4e-112	410.6	Bacilli	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100		R00966	RC00063	ko00000,ko00001,ko01000			iSB619.SA_RS11010	Bacteria	1TPMT@1239,4H9Y0@91061,COG0035@1,COG0035@2	NA|NA|NA	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NHHNPPIF_00497	1046629.Ssal_01837	8e-10	69.7	Bacilli	sacB	GO:0005575,GO:0005576	2.4.1.10,2.4.1.9,3.2.1.26	ko:K00692,ko:K01193,ko:K20811	ko00052,ko00500,ko01100,ko02020,map00052,map00500,map01100,map02020		R00801,R00802,R02410,R03635,R03921,R04194,R05140,R06088	RC00028,RC00077,RC00247	ko00000,ko00001,ko01000,ko01003		GH32,GH68		Bacteria	1TR8C@1239,4HBYU@91061,COG1621@1,COG1621@2	NA|NA|NA	G	Belongs to the glycosyl hydrolase 68 family
NHHNPPIF_00498	264199.stu0353	2.8e-221	774.2	Bacilli	malY		4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230		R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007				Bacteria	1TP5G@1239,4H9PE@91061,COG1168@1,COG1168@2	NA|NA|NA	E	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NHHNPPIF_00499	264199.stu0352	1.1e-200	705.7	Bacilli	metB	GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846	2.5.1.48,4.4.1.8	ko:K01739,ko:K01760	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPC7@1239,4HAFQ@91061,COG0626@1,COG0626@2	NA|NA|NA	E	cystathionine
NHHNPPIF_00500	1282665.H353_06423	2.3e-91	341.7	Bacilli	pacL		3.6.3.8,3.6.3.9	ko:K01537,ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978				ko00000,ko00001,ko01000,ko04147	3.A.3.1,3.A.3.2			Bacteria	1TPF5@1239,4HTQ4@91061,COG0474@1,COG0474@2	NA|NA|NA	P	cation transport ATPase
NHHNPPIF_00501	264199.stu0350	1e-282	978.8	Bacilli	ytgP	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K03328,ko:K06409					ko00000,ko02000	2.A.66.2,2.A.66.2.14			Bacteria	1TNYX@1239,4H9RY@91061,COG2244@1,COG2244@2	NA|NA|NA	S	Membrane protein involved in the export of O-antigen and teichoic acid
NHHNPPIF_00502	264199.stu0349	7.9e-274	949.1	Bacilli	murE		6.3.2.13,6.3.2.7	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100		R02786,R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011				Bacteria	1TPQE@1239,4H9T1@91061,COG0769@1,COG0769@2	NA|NA|NA	M	to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NHHNPPIF_00503	264199.stu0348	3.6e-219	767.3	Bacilli	femA		2.3.2.10,2.3.2.16,2.3.2.17,2.3.2.18	ko:K05363,ko:K11693,ko:K11694,ko:K11695,ko:K12554	ko00550,ko01100,map00550,map01100		R08776,R08777,R08778,R08779,R08780	RC00055,RC00064,RC00096	ko00000,ko00001,ko01000,ko01011				Bacteria	1UZIJ@1239,4HAQ3@91061,COG2348@1,COG2348@2	NA|NA|NA	V	protein involved in methicillin resistance
NHHNPPIF_00505	904306.HMPREF9192_0063	1.8e-45	188.7	Bacilli	yvdD		3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240		R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000				Bacteria	1UKED@1239,4HGSU@91061,COG1611@1,COG1611@2	NA|NA|NA	S	Belongs to the LOG family
NHHNPPIF_00506	264199.stu0345	1.7e-57	228.4	Bacilli	rbfA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360		ko:K02834					ko00000,ko03009				Bacteria	1VA0P@1239,4HII1@91061,COG0858@1,COG0858@2	NA|NA|NA	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NHHNPPIF_00507	264199.stu0344	0.0	1174.5	Bacilli	infB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464		ko:K02519					ko00000,ko03012,ko03029				Bacteria	1TPAI@1239,4HA8S@91061,COG0532@1,COG0532@2	NA|NA|NA	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NHHNPPIF_00508	264199.stu0343	1.4e-41	175.3	Bacilli	ylxQ			ko:K07590,ko:K07742	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1VEYG@1239,4HNY7@91061,COG1358@1,COG1358@2	NA|NA|NA	J	ribosomal protein
NHHNPPIF_00509	264199.stu0342	3e-47	194.1	Bacilli	ylxR			ko:K02600,ko:K07742					ko00000,ko03009,ko03021				Bacteria	1VEJS@1239,4HKBY@91061,COG2740@1,COG2740@2	NA|NA|NA	K	Nucleic-acid-binding protein implicated in transcription termination
NHHNPPIF_00510	322159.STER_0380	3.1e-212	744.2	Bacilli	nusA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141		ko:K02600,ko:K02945	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03009,ko03011,ko03021				Bacteria	1TPB3@1239,4HA7F@91061,COG0195@1,COG0195@2	NA|NA|NA	K	Participates in both transcription termination and antitermination
NHHNPPIF_00511	264199.stu0340	3.9e-81	307.4	Bacilli	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576		ko:K09748					ko00000,ko03009				Bacteria	1V6KT@1239,4HH88@91061,COG0779@1,COG0779@2	NA|NA|NA	S	Required for maturation of 30S ribosomal subunits
NHHNPPIF_00512	264199.stu0339	1.5e-217	761.9	Bacilli	brpA												Bacteria	1TR1B@1239,4HA09@91061,COG1316@1,COG1316@2	NA|NA|NA	K	Transcriptional
NHHNPPIF_00513	264199.stu0338	3.2e-92	344.4	Firmicutes	XK27_05885		2.3.1.82	ko:K18816					br01600,ko00000,ko01000,ko01504				Bacteria	1VA2F@1239,COG1247@1,COG1247@2	NA|NA|NA	M	Acetyltransferase GNAT Family
NHHNPPIF_00514	264199.stu0337	1.4e-77	295.4	Bacilli	ydiB	GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.7.1.221,5.1.1.1	ko:K01775,ko:K06925,ko:K07102	ko00473,ko00520,ko01100,ko01502,map00473,map00520,map01100,map01502		R00401,R08968,R11024	RC00002,RC00078,RC00285	ko00000,ko00001,ko01000,ko01011,ko03016				Bacteria	1V6CV@1239,4HIIF@91061,COG0802@1,COG0802@2	NA|NA|NA	M	ATPase or kinase
NHHNPPIF_00515	904306.HMPREF9192_0073	3e-241	840.9	Bacilli	pbuO			ko:K06901					ko00000,ko02000	2.A.1.40			Bacteria	1TQC6@1239,4HANG@91061,COG2252@1,COG2252@2	NA|NA|NA	S	permease
NHHNPPIF_00516	322159.STER_0374	5.6e-152	543.5	Bacilli	yitU		3.1.3.104	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R07280	RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	1TREF@1239,4H9Y9@91061,COG0561@1,COG0561@2	NA|NA|NA	S	hydrolases of the HAD superfamily
NHHNPPIF_00517	264199.stu0334	4.9e-139	500.4	Bacilli	XK27_00940		1.2.1.70,3.5.1.9	ko:K02492,ko:K07130	ko00380,ko00630,ko00860,ko01100,ko01110,ko01120,map00380,map00630,map00860,map01100,map01110,map01120	M00038,M00121	R00988,R01959,R04109,R04911	RC00055,RC00149,RC00263,RC00323	ko00000,ko00001,ko00002,ko01000				Bacteria	1TRBQ@1239,4HCAB@91061,COG1878@1,COG1878@2	NA|NA|NA	S	Metal-dependent hydrolase
NHHNPPIF_00518	322159.STER_0372	2.4e-173	614.8	Bacilli	manL		2.7.1.191	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1			Bacteria	1TQJ4@1239,4H9Z8@91061,COG2893@1,COG2893@2,COG3444@1,COG3444@2	NA|NA|NA	G	pts system
NHHNPPIF_00519	322159.STER_0371	3.9e-116	424.5	Bacilli	manM			ko:K02795,ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1			Bacteria	1TPKK@1239,4H9QI@91061,COG3715@1,COG3715@2	NA|NA|NA	G	pts system
NHHNPPIF_00520	264199.stu0331	6.2e-168	596.7	Bacilli	manN			ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1			Bacteria	1TQA3@1239,4HA3K@91061,COG3716@1,COG3716@2	NA|NA|NA	G	PTS system mannose fructose sorbose family IID component
NHHNPPIF_00521	322159.STER_0369	4.2e-62	243.8	Bacilli	manO												Bacteria	1VF36@1239,4HPYI@91061,COG4687@1,COG4687@2	NA|NA|NA	S	protein conserved in bacteria
NHHNPPIF_00522	264199.stu0329	8.6e-232	809.3	Bacilli	serS	GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iAF987.Gmet_3528,iSDY_1059.SDY_2368	Bacteria	1TP4W@1239,4H9Y4@91061,COG0172@1,COG0172@2	NA|NA|NA	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NHHNPPIF_00525	1123299.AUKZ01000014_gene1677	3.9e-17	94.7	Bacilli													Bacteria	1TQN4@1239,4HN8F@91061,COG0358@1,COG0358@2,COG4227@1,COG4227@2	NA|NA|NA	L	Psort location Cytoplasmic, score
NHHNPPIF_00527	322159.STER_1785	6.3e-226	789.6	Bacilli	tgt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773			R03789,R10209	RC00063	ko00000,ko01000,ko03016				Bacteria	1TNZ4@1239,4HCNM@91061,COG0343@1,COG0343@2	NA|NA|NA	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NHHNPPIF_00528	322159.STER_1786	1e-33	148.7	Bacilli				ko:K07491					ko00000				Bacteria	1V1CM@1239,4HGN6@91061,COG1943@1,COG1943@2	NA|NA|NA	L	Transposase
NHHNPPIF_00529	264199.stu0292	0.0	1872.4	Bacilli													Bacteria	1TPTH@1239,4HAHU@91061,COG1020@1,COG1020@2	NA|NA|NA	Q	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHHNPPIF_00530	264199.stu0293	0.0	1093.6	Bacilli			3.3.1.1,3.6.1.55,3.6.1.67	ko:K01251,ko:K03574,ko:K19965	ko00270,ko00790,ko01100,map00270,map00790,map01100	M00035,M00126	R00192,R04638,R04936	RC00002,RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko03400,ko04147				Bacteria	1V1P7@1239,4HFQH@91061,COG0499@1,COG0499@2,COG1051@1,COG1051@2	NA|NA|NA	F	NUDIX domain
NHHNPPIF_00531	264199.stu0294	3.8e-205	720.7	Firmicutes													Bacteria	1UHQE@1239,COG0477@1,COG0477@2	NA|NA|NA	EGP	Transmembrane secretion effector
NHHNPPIF_00532	1161413.HMPREF1510_1836	2.3e-31	141.0	Firmicutes				ko:K07497					ko00000				Bacteria	1TQQY@1239,COG2801@1,COG2801@2	NA|NA|NA	L	Integrase core domain protein
NHHNPPIF_00533	322159.STER_1959	8.2e-27	125.9	Bacilli													Bacteria	1VENK@1239,4HNKV@91061,COG2261@1,COG2261@2	NA|NA|NA	S	Membrane
NHHNPPIF_00534	322159.STER_1960	1.7e-99	368.6	Bacilli													Bacteria	1VK2R@1239,2ED8H@1,33752@2,4HQ99@91061	NA|NA|NA		
NHHNPPIF_00535	264199.stu1984	1.8e-23	114.4	Bacteria													Bacteria	COG5547@1,COG5547@2	NA|NA|NA	S	Small integral membrane protein
NHHNPPIF_00536	264199.stu1986	6.5e-83	313.5	Bacteria													Bacteria	COG1302@1,COG1302@2	NA|NA|NA	M	Protein conserved in bacteria
NHHNPPIF_00537	264199.stu1987	9.2e-11	72.4	Bacteria													Bacteria	COG3237@1,COG3237@2	NA|NA|NA	K	CsbD-like
NHHNPPIF_00538	322159.STER_1959	3.7e-27	127.1	Bacilli													Bacteria	1VENK@1239,4HNKV@91061,COG2261@1,COG2261@2	NA|NA|NA	S	Membrane
NHHNPPIF_00539	322159.STER_1960	1.7e-99	368.6	Bacilli													Bacteria	1VK2R@1239,2ED8H@1,33752@2,4HQ99@91061	NA|NA|NA		
NHHNPPIF_00540	264199.stu1984	1.8e-23	114.4	Bacteria													Bacteria	COG5547@1,COG5547@2	NA|NA|NA	S	Small integral membrane protein
NHHNPPIF_00541	264199.stu1986	6.5e-83	313.5	Bacteria													Bacteria	COG1302@1,COG1302@2	NA|NA|NA	M	Protein conserved in bacteria
NHHNPPIF_00542	264199.stu1987	9.2e-11	72.4	Bacteria													Bacteria	COG3237@1,COG3237@2	NA|NA|NA	K	CsbD-like
NHHNPPIF_00543	1116231.SMA_0321	1.1e-32	145.2	Bacilli													Bacteria	1TP4C@1239,4HAXJ@91061,COG3328@1,COG3328@2	NA|NA|NA	L	Transposase
NHHNPPIF_00544	904306.HMPREF9192_0086	8.3e-89	333.2	Bacilli	yrdC		3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100		R01268	RC00100	ko00000,ko00001,ko01000				Bacteria	1V70H@1239,4HJXC@91061,COG1335@1,COG1335@2	NA|NA|NA	Q	isochorismatase
NHHNPPIF_00545	322159.STER_0359	1.1e-245	855.5	Bacilli	der	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.1.1.399,1.1.1.95	ko:K00058,ko:K03977	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko03009,ko04147				Bacteria	1TPNM@1239,4HAJ6@91061,COG1160@1,COG1160@2	NA|NA|NA	S	GTPase that plays an essential role in the late steps of ribosome biogenesis
NHHNPPIF_00546	264199.stu0321	8.9e-167	592.8	Bacilli	dnaI	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837		ko:K11144					ko00000,ko03032				Bacteria	1TPZX@1239,4HABS@91061,COG1484@1,COG1484@2	NA|NA|NA	L	Primosomal protein DnaI
NHHNPPIF_00547	264199.stu0320	2.7e-216	757.7	Bacteria	dnaB			ko:K03346					ko00000,ko03032				Bacteria	COG3611@1,COG3611@2	NA|NA|NA	L	Replication initiation and membrane attachment
NHHNPPIF_00548	264199.stu0319	2.8e-82	311.2	Bacilli	nrdR	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141		ko:K07738					ko00000,ko03000				Bacteria	1V3JA@1239,4HGXA@91061,COG1327@1,COG1327@2	NA|NA|NA	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NHHNPPIF_00549	264199.stu0318	1.2e-275	955.3	Bacilli													Bacteria	1UHQC@1239,4HWKS@91061,COG0642@1,COG2205@2	NA|NA|NA	T	PhoQ Sensor
NHHNPPIF_00550	264199.stu0317	3.9e-122	444.1	Bacilli													Bacteria	1TS81@1239,4H9NE@91061,COG0745@1,COG0745@2	NA|NA|NA	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHHNPPIF_00551	322159.STER_0353	2.4e-90	338.2	Bacilli	yceD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464		ko:K07040					ko00000				Bacteria	1VB08@1239,4HME9@91061,COG1399@1,COG1399@2	NA|NA|NA	K	metal-binding, possibly nucleic acid-binding protein
NHHNPPIF_00552	264199.stu0315	3.1e-130	471.1	Bacilli	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501					ko00000,ko01000,ko03009,ko03036				Bacteria	1TPBT@1239,4HAAZ@91061,COG0357@1,COG0357@2	NA|NA|NA	J	Ribosomal RNA small subunit methyltransferase G
NHHNPPIF_00553	322159.STER_0351	2.2e-241	841.3	Bacilli				ko:K03498					ko00000,ko02000	2.A.38.1,2.A.38.4			Bacteria	1TQ4S@1239,4H9ME@91061,COG0168@1,COG0168@2	NA|NA|NA	P	COG0168 Trk-type K transport systems, membrane components
NHHNPPIF_00554	264199.stu0313	1.9e-121	441.8	Bacilli	ktrA			ko:K03499					ko00000,ko02000	2.A.38.1,2.A.38.4			Bacteria	1TQ9H@1239,4HBPH@91061,COG0569@1,COG0569@2	NA|NA|NA	P	COG0569 K transport systems, NAD-binding component
NHHNPPIF_00555	1123298.KB904063_gene687	1.4e-11	75.5	Bacilli	ulaG	GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009056,GO:0009109,GO:0009111,GO:0009987,GO:0016052,GO:0016054,GO:0016787,GO:0016788,GO:0019752,GO:0019852,GO:0019854,GO:0030145,GO:0035460,GO:0042365,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046872,GO:0046914,GO:0051186,GO:0051187,GO:0052689,GO:0071704,GO:1901575		ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	M00550	R07677	RC02793	ko00000,ko00001,ko00002,ko01000			iAF1260.b4192,iAPECO1_1312.APECO1_2200,iBWG_1329.BWG_3904,iEC55989_1330.EC55989_4749,iECDH10B_1368.ECDH10B_4387,iECH74115_1262.ECH74115_5708,iECIAI1_1343.ECIAI1_4425,iECIAI39_1322.ECIAI39_4657,iECO111_1330.ECO111_5022,iECO26_1355.ECO26_5358,iECSE_1348.ECSE_4490,iECSP_1301.ECSP_5292,iECUMN_1333.ECUMN_4725,iECW_1372.ECW_m4554,iEKO11_1354.EKO11_4120,iEcE24377_1341.EcE24377A_4752,iEcHS_1320.EcHS_A4436,iEcolC_1368.EcolC_3821,iJO1366.b4192,iUTI89_1310.UTI89_C4792,iWFL_1372.ECW_m4554,iY75_1357.Y75_RS21830,iYL1228.KPN_04585,ic_1306.c5280	Bacteria	1TSFV@1239,4HBNW@91061,COG2220@1,COG2220@2	NA|NA|NA	S	L-ascorbate 6-phosphate lactonase
NHHNPPIF_00556	264199.stu0312	0.0	1310.4	Bacilli	tkt		2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPIB@1239,4HADA@91061,COG0021@1,COG0021@2	NA|NA|NA	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NHHNPPIF_00557	322159.STER_0348	1.2e-149	535.8	Bacilli	cbiQ			ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35		iSB619.SA_RS14165	Bacteria	1TPMV@1239,4HBTW@91061,COG0619@1,COG0619@2	NA|NA|NA	P	cobalt transport
NHHNPPIF_00558	322159.STER_0347	0.0	1087.8	Bacilli	ykoD	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085		ko:K02006,ko:K16786,ko:K16787	ko02010,map02010	M00245,M00246,M00582			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35			Bacteria	1TPH8@1239,4HAJM@91061,COG1122@1,COG1122@2	NA|NA|NA	P	abc transporter atp-binding protein
NHHNPPIF_00559	322159.STER_0346	8e-94	349.7	Bacilli				ko:K16924,ko:K16927		M00582			ko00000,ko00002,ko02000	3.A.1.29,3.A.1.32			Bacteria	1V1GT@1239,4HGAE@91061,COG4720@1,COG4720@2	NA|NA|NA	S	UPF0397 protein
NHHNPPIF_00560	322159.STER_0345	4.9e-159	567.0	Bacilli	salL	GO:0003674,GO:0003824,GO:0016740,GO:0016765	2.5.1.63,2.5.1.94	ko:K09134,ko:K21153,ko:K22205					ko00000,ko01000				Bacteria	1TSR3@1239,4HAW6@91061,COG1912@1,COG1912@2	NA|NA|NA	S	S-adenosyl-l-methionine hydroxide adenosyltransferase
NHHNPPIF_00561	264199.stu0303	6.1e-211	740.0	Bacilli	sstT	GO:0003333,GO:0003674,GO:0005215,GO:0005283,GO:0005295,GO:0005310,GO:0005342,GO:0005343,GO:0005416,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006820,GO:0006835,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015077,GO:0015081,GO:0015171,GO:0015175,GO:0015291,GO:0015293,GO:0015294,GO:0015318,GO:0015370,GO:0015672,GO:0015711,GO:0015804,GO:0015849,GO:0016020,GO:0016021,GO:0017153,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032329,GO:0034220,GO:0035725,GO:0044425,GO:0044464,GO:0046873,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1903825,GO:1905039		ko:K07862					ko00000,ko02000	2.A.23.4		iAF1260.b3089,iBWG_1329.BWG_2799,iECDH10B_1368.ECDH10B_3265,iECDH1ME8569_1439.ECDH1ME8569_2984,iECH74115_1262.ECH74115_4404,iECIAI1_1343.ECIAI1_3235,iECO103_1326.ECO103_3834,iECO111_1330.ECO111_3911,iECO26_1355.ECO26_4192,iECP_1309.ECP_3180,iECSE_1348.ECSE_3370,iECSP_1301.ECSP_4063,iECUMN_1333.ECUMN_3573,iECW_1372.ECW_m3356,iECs_1301.ECs3971,iEKO11_1354.EKO11_0630,iETEC_1333.ETEC_3359,iEcDH1_1363.EcDH1_0612,iEcE24377_1341.EcE24377A_3557,iG2583_1286.G2583_3813,iJO1366.b3089,iJR904.b3089,iSFV_1184.SFV_3130,iSSON_1240.SSON_3242,iUMNK88_1353.UMNK88_3845,iWFL_1372.ECW_m3356,iY75_1357.Y75_RS16050,iYL1228.KPN_03517,iZ_1308.Z4442	Bacteria	1TPD2@1239,4HBEC@91061,COG3633@1,COG3633@2	NA|NA|NA	E	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NHHNPPIF_00562	264199.stu0302	8.8e-98	363.2	Bacilli	metI			ko:K02072	ko02010,map02010	M00238			ko00000,ko00001,ko00002,ko02000	3.A.1.24			Bacteria	1V0GE@1239,4HFMB@91061,COG2011@1,COG2011@2	NA|NA|NA	P	ABC transporter (Permease
NHHNPPIF_00563	264199.stu0301	7.5e-189	666.4	Bacilli	metN			ko:K02071	ko02010,map02010	M00238			ko00000,ko00001,ko00002,ko02000	3.A.1.24			Bacteria	1TPPN@1239,4H9VX@91061,COG1135@1,COG1135@2	NA|NA|NA	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NHHNPPIF_00564	264199.stu0300	2.1e-61	241.5	Bacteria	dapE		3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000				Bacteria	COG0624@1,COG0624@2	NA|NA|NA	E	succinyl-diaminopimelate desuccinylase activity
NHHNPPIF_00565	904306.HMPREF9192_0106	4.8e-76	290.4	Bacilli	dapE		3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP2D@1239,4HB9G@91061,COG0624@1,COG0624@2	NA|NA|NA	E	COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
NHHNPPIF_00566	264199.stu0298	2.5e-77	294.7	Bacilli	dapE		3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP2D@1239,4HB9G@91061,COG0624@1,COG0624@2	NA|NA|NA	E	COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
NHHNPPIF_00567	264199.stu0297	2.3e-162	578.2	Bacilli	metQ			ko:K02073	ko02010,map02010	M00238			ko00000,ko00001,ko00002,ko02000	3.A.1.24			Bacteria	1TQAS@1239,4HCTA@91061,COG1464@1,COG1464@2	NA|NA|NA	M	Belongs to the NlpA lipoprotein family
NHHNPPIF_00568	1046629.Ssal_00654	5.9e-25	119.4	Bacilli	glgB	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033554,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0071944,GO:1901576	2.4.1.18,3.2.1.141,3.2.1.20	ko:K00700,ko:K01187,ko:K01236,ko:K17734	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	M00565	R00028,R00801,R00802,R02110,R06087,R06088,R09995,R11256	RC00028,RC00049,RC00077	ko00000,ko00001,ko00002,ko01000,ko01002,ko04147		CBM48,GH13,GH31	iAPECO1_1312.APECO1_3025,iECNA114_1301.ECNA114_3542,iECOK1_1307.ECOK1_3857,iECS88_1305.ECS88_3830,iECSF_1327.ECSF_3253,iJN678.glgB,iLF82_1304.LF82_0837,iNRG857_1313.NRG857_17030,iUTI89_1310.UTI89_C3941	Bacteria	1TP4M@1239,4HAPM@91061,COG0296@1,COG0296@2	NA|NA|NA	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NHHNPPIF_00569	1046629.Ssal_00653	2.1e-82	312.0	Bacilli	pulA		3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110		R02111		ko00000,ko00001,ko01000		CBM48,GH13		Bacteria	1TP3M@1239,4HBP5@91061,COG1523@1,COG1523@2	NA|NA|NA	G	belongs to the glycosyl hydrolase 13 family
NHHNPPIF_00570	904306.HMPREF9192_0969	6.6e-84	316.6	Bacilli	pulA		3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110		R02111		ko00000,ko00001,ko01000		CBM48,GH13		Bacteria	1TP3M@1239,4HBP5@91061,COG1523@1,COG1523@2	NA|NA|NA	G	belongs to the glycosyl hydrolase 13 family
NHHNPPIF_00571	1046629.Ssal_00653	3.6e-117	427.9	Bacilli	pulA		3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110		R02111		ko00000,ko00001,ko01000		CBM48,GH13		Bacteria	1TP3M@1239,4HBP5@91061,COG1523@1,COG1523@2	NA|NA|NA	G	belongs to the glycosyl hydrolase 13 family
NHHNPPIF_00572	264199.stu1416	0.0	1441.0	Bacilli	ftsK	GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141		ko:K03466					ko00000,ko03036	3.A.12			Bacteria	1TPJR@1239,4H9WA@91061,COG1674@1,COG1674@2	NA|NA|NA	D	Belongs to the FtsK SpoIIIE SftA family
NHHNPPIF_00573	264199.stu1417	5e-187	660.2	Bacilli	trxB1		1.18.1.2,1.19.1.1	ko:K21567					ko00000,ko01000				Bacteria	1TRPN@1239,4H9V7@91061,COG0492@1,COG0492@2	NA|NA|NA	C	Ferredoxin--NADP reductase
NHHNPPIF_00574	264199.stu1418	1.4e-135	488.8	Bacilli	trmD	GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228,4.6.1.12	ko:K00554,ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R00597,R05637	RC00002,RC00003,RC00334,RC01440	ko00000,ko00001,ko00002,ko01000,ko03016				Bacteria	1TPBV@1239,4HBFV@91061,COG0336@1,COG0336@2	NA|NA|NA	J	Belongs to the RNA methyltransferase TrmD family
NHHNPPIF_00575	322159.STER_1384	1.3e-93	349.0	Bacilli	rimM	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360		ko:K02860					ko00000,ko03009				Bacteria	1V6HD@1239,4HH3H@91061,COG0806@1,COG0806@2	NA|NA|NA	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NHHNPPIF_00578	322159.STER_1387	2.2e-114	418.3	Bacilli	vraR			ko:K07694,ko:K11618	ko02020,map02020	M00480,M00481,M00754			ko00000,ko00001,ko00002,ko02022				Bacteria	1TQ1U@1239,4HA4B@91061,COG2197@1,COG2197@2	NA|NA|NA	K	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHHNPPIF_00579	264199.stu1421	3.8e-174	617.5	Bacilli	vraS		2.7.13.3	ko:K07673,ko:K07681,ko:K11617	ko02020,map02020	M00471,M00480,M00481,M00754			ko00000,ko00001,ko00002,ko01000,ko01001,ko02022				Bacteria	1TPDG@1239,4HC7E@91061,COG4585@1,COG4585@2	NA|NA|NA	T	Histidine kinase
NHHNPPIF_00580	264199.stu1422	9.1e-119	433.0	Bacteria	yvqF			ko:K11622	ko02020,map02020				ko00000,ko00001				Bacteria	COG4758@1,COG4758@2	NA|NA|NA	KT	membrane
NHHNPPIF_00581	264199.stu1425	5.3e-307	1059.7	Bacilli	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K12132					ko00000,ko01000,ko01001				Bacteria	1TP3F@1239,4H9KD@91061,COG0515@1,COG0515@2,COG2815@1,COG2815@2	NA|NA|NA	KLT	serine threonine protein kinase
NHHNPPIF_00582	264199.stu1426	2.9e-131	474.6	Bacilli	stp		3.1.3.16	ko:K20074					ko00000,ko01000,ko01009				Bacteria	1V6K5@1239,4HCDR@91061,COG0631@1,COG0631@2	NA|NA|NA	T	phosphatase
NHHNPPIF_00583	264199.stu1427	2.2e-246	857.8	Bacilli	sun	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500					ko00000,ko01000,ko03009				Bacteria	1TP3N@1239,4HBQ6@91061,COG0144@1,COG0144@2,COG0781@1,COG0781@2	NA|NA|NA	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NHHNPPIF_00584	264199.stu1428	1e-173	615.9	Bacilli	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970		R03940	RC00026,RC00165	ko00000,ko00001,ko01000			iSB619.SA_RS06010	Bacteria	1TQ32@1239,4HART@91061,COG0223@1,COG0223@2	NA|NA|NA	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NHHNPPIF_00585	264199.stu1429	0.0	1580.8	Bacilli	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576		ko:K04066	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1TNYB@1239,4H9WW@91061,COG1198@1,COG1198@2	NA|NA|NA	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NHHNPPIF_00586	264199.stu1430	2.7e-46	191.0	Bacteria	rpoZ	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400				Bacteria	COG1758@1,COG1758@2	NA|NA|NA	K	DNA-directed 5'-3' RNA polymerase activity
NHHNPPIF_00587	264199.stu1431	2e-112	411.8	Bacilli	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000			iYO844.BSU15680	Bacteria	1TP0M@1239,4HAYW@91061,COG0194@1,COG0194@2	NA|NA|NA	F	Essential for recycling GMP and indirectly, cGMP
NHHNPPIF_00588	264199.stu1432	6.7e-214	750.0	Bacilli	ftsY			ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7			Bacteria	1TPRI@1239,4HA6A@91061,COG0552@1,COG0552@2	NA|NA|NA	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NHHNPPIF_00589	322159.STER_1400	5.3e-150	537.0	Bacilli	XK27_02985												Bacteria	1TR2E@1239,4HGA9@91061,COG0561@1,COG0561@2	NA|NA|NA	S	overlaps another CDS with the same product name
NHHNPPIF_00590	322159.STER_1401	2.1e-148	531.6	Bacilli	supH												Bacteria	1V2JE@1239,4IPK2@91061,COG0561@1,COG0561@2	NA|NA|NA	S	overlaps another CDS with the same product name
NHHNPPIF_00591	322159.STER_1402	8.6e-63	246.1	Bacilli	yvoA_1			ko:K07979					ko00000,ko03000				Bacteria	1VFD0@1239,4HNIT@91061,COG1725@1,COG1725@2	NA|NA|NA	K	Transcriptional
NHHNPPIF_00592	264199.stu1436	9.8e-121	439.5	Bacilli	skfE			ko:K01990		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1TPUP@1239,4HGHM@91061,COG1131@1,COG1131@2	NA|NA|NA	V	abc transporter atp-binding protein
NHHNPPIF_00593	322159.STER_1404	5.6e-133	480.3	Bacteria				ko:K01990		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	COG1131@1,COG1131@2	NA|NA|NA	V	ATPase activity
NHHNPPIF_00594	264199.stu1438	6.6e-40	169.5	Bacilli	oppF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1V36J@1239,4HCM4@91061,COG4608@1,COG4608@2	NA|NA|NA	P	Belongs to the ABC transporter superfamily
NHHNPPIF_00595	264199.stu0692	3.5e-285	986.9	Bacilli	lysS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1TP2P@1239,4H9X4@91061,COG1190@1,COG1190@2	NA|NA|NA	J	Belongs to the class-II aminoacyl-tRNA synthetase family
NHHNPPIF_00596	322159.STER_0734	1.9e-15	87.4	Bacilli													Bacteria	1VWTU@1239,4HX18@91061,COG1388@1,COG1388@2	NA|NA|NA	M	LysM domain
NHHNPPIF_00597	904306.HMPREF9192_1148	2.4e-58	231.9	Bacteria													Bacteria	COG1388@1,COG1388@2	NA|NA|NA	M	LysM domain
NHHNPPIF_00598	904293.HMPREF9176_0571	3.1e-20	104.8	Bacilli													Bacteria	1VVCA@1239,2BXK6@1,33WGZ@2,4HWEI@91061	NA|NA|NA		
NHHNPPIF_00599	264199.stu0696	6.4e-173	613.2	Bacilli				ko:K07025					ko00000				Bacteria	1V5P7@1239,4HHGY@91061,COG1011@1,COG1011@2	NA|NA|NA	S	hydrolase
NHHNPPIF_00600	264199.stu0697	4.3e-115	420.6	Bacilli	pgm6		5.4.2.11,5.4.2.12	ko:K01834,ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147				Bacteria	1V7EZ@1239,4HJCK@91061,COG0406@1,COG0406@2	NA|NA|NA	G	Phosphoglycerate mutase
NHHNPPIF_00601	264199.stu0698	7.9e-82	309.7	Bacilli	ybaK			ko:K03976					ko00000,ko01000,ko03016				Bacteria	1V6JF@1239,4HIH1@91061,COG2606@1,COG2606@2	NA|NA|NA	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NHHNPPIF_00602	264199.stu0699	4.5e-145	520.8	Bacilli	XK27_00880		3.5.1.28	ko:K01447,ko:K07273			R04112	RC00064,RC00141	ko00000,ko01000				Bacteria	1V2YH@1239,4HI8U@91061,COG3757@1,COG3757@2	NA|NA|NA	M	Glycosyl hydrolase, family 25
NHHNPPIF_00603	1123304.AQYA01000028_gene1720	2.7e-27	128.3	Bacteria													Bacteria	COG2461@1,COG2461@2	NA|NA|NA	P	Hemerythrin HHE cation binding domain protein
NHHNPPIF_00604	264199.stu0701	6.1e-114	416.8	Bacilli			1.14.14.5	ko:K04091	ko00920,map00920		R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000				Bacteria	1VJRB@1239,4ISN7@91061,COG2141@1,COG2141@2	NA|NA|NA	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHHNPPIF_00605	904306.HMPREF9192_1160	1.7e-10	70.5	Bacilli	MA20_36090												Bacteria	1VEWD@1239,4IQU0@91061,COG1073@1,COG1073@2	NA|NA|NA	S	Protein of unknown function (DUF2974)
NHHNPPIF_00606	1046629.Ssal_01417	7.9e-37	159.5	Bacilli	MA20_36090												Bacteria	1VEWD@1239,4IQU0@91061,COG1073@1,COG1073@2	NA|NA|NA	S	Protein of unknown function (DUF2974)
NHHNPPIF_00607	904306.HMPREF9192_1160	8e-18	95.5	Bacilli	MA20_36090												Bacteria	1VEWD@1239,4IQU0@91061,COG1073@1,COG1073@2	NA|NA|NA	S	Protein of unknown function (DUF2974)
NHHNPPIF_00608	264199.stu0704	3.7e-48	197.2	Bacilli	sdh		1.1.1.276,1.1.1.313,1.1.1.381	ko:K05886,ko:K15373,ko:K16066	ko00240,ko00260,ko00430,ko01100,map00240,map00260,map00430,map01100		R02600,R09289,R10851,R10852	RC00087,RC00525,RC03288	ko00000,ko00001,ko01000				Bacteria	1V08N@1239,4IPTJ@91061,COG4221@1,COG4221@2	NA|NA|NA	S	Belongs to the short-chain dehydrogenases reductases (SDR) family
NHHNPPIF_00609	435842.HMPREF0848_00357	1.7e-70	271.9	Bacilli	sdh		1.1.1.276,1.1.1.313,1.1.1.381	ko:K05886,ko:K15373,ko:K16066	ko00240,ko00260,ko00430,ko01100,map00240,map00260,map00430,map01100		R02600,R09289,R10851,R10852	RC00087,RC00525,RC03288	ko00000,ko00001,ko01000				Bacteria	1V08N@1239,4IPTJ@91061,COG4221@1,COG4221@2	NA|NA|NA	S	Belongs to the short-chain dehydrogenases reductases (SDR) family
NHHNPPIF_00610	322159.STER_0747	0.0	1941.0	Bacilli	hsdR		3.1.21.3	ko:K01153					ko00000,ko01000,ko02048				Bacteria	1TP7S@1239,4HB5A@91061,COG0610@1,COG0610@2	NA|NA|NA	L	Subunit R is required for both nuclease and ATPase activities, but not for modification
NHHNPPIF_00611	1123304.AQYA01000035_gene1027	8.7e-216	756.9	Bacilli	prrC												Bacteria	1TT67@1239,4HCP2@91061,COG4694@1,COG4694@2	NA|NA|NA	S	AAA domain
NHHNPPIF_00612	264199.stu0708	5e-125	454.5	Bacilli	hsdS		3.1.21.3	ko:K01154					ko00000,ko01000,ko02048				Bacteria	1TP5N@1239,4HFAV@91061,COG0732@1,COG0732@2	NA|NA|NA	V	type I restriction modification DNA specificity domain protein
NHHNPPIF_00613	904306.HMPREF9192_1168	4.8e-105	387.1	Firmicutes													Bacteria	1W2YW@1239,299SU@1,2ZWV2@2	NA|NA|NA		
NHHNPPIF_00614	322159.STER_0752	7.5e-135	486.5	Bacilli													Bacteria	1V2TW@1239,4HHGA@91061,COG2852@1,COG2852@2	NA|NA|NA	S	Protein conserved in bacteria
NHHNPPIF_00615	904306.HMPREF9192_1172	2.4e-303	1047.3	Bacilli	hsdM		2.1.1.72	ko:K03427					ko00000,ko01000,ko02048				Bacteria	1TPGZ@1239,4HA1J@91061,COG0286@1,COG0286@2	NA|NA|NA	V	type I restriction-modification system
NHHNPPIF_00616	435842.HMPREF0848_00367	1.2e-49	202.2	Bacilli													Bacteria	1V1A7@1239,4HG0B@91061,COG5464@1,COG5464@2	NA|NA|NA	S	PD-(D/E)XK nuclease family transposase
NHHNPPIF_00617	1046629.Ssal_01404	1.1e-90	339.3	Bacteria													Bacteria	COG5464@1,COG5464@2	NA|NA|NA	S	double-stranded DNA endodeoxyribonuclease activity
NHHNPPIF_00618	904306.HMPREF9192_1174	5.1e-163	580.5	Bacilli	spd			ko:K15051					ko00000				Bacteria	1TR37@1239,4HK9Z@91061,COG2169@1,COG2169@2	NA|NA|NA	F	DNA RNA non-specific endonuclease
NHHNPPIF_00619	322159.STER_0756	9e-93	346.3	Bacilli	lemA			ko:K03744					ko00000				Bacteria	1V1G7@1239,4IR1J@91061,COG1704@1,COG1704@2	NA|NA|NA	S	LemA family
NHHNPPIF_00620	904306.HMPREF9192_1176	6.4e-133	480.3	Bacilli	htpX			ko:K03799		M00743			ko00000,ko00002,ko01000,ko01002				Bacteria	1TP23@1239,4HB11@91061,COG0501@1,COG0501@2	NA|NA|NA	O	Belongs to the peptidase M48B family
NHHNPPIF_00621	264199.stu0716	4.2e-75	287.3	Bacilli				ko:K16924,ko:K16927		M00582			ko00000,ko00002,ko02000	3.A.1.29,3.A.1.32			Bacteria	1V5GD@1239,4HI8Y@91061,COG4720@1,COG4720@2	NA|NA|NA	S	Psort location CytoplasmicMembrane, score
NHHNPPIF_00622	1046629.Ssal_01392	6.2e-56	223.4	Bacilli													Bacteria	1VF26@1239,2DNM7@1,32Y2X@2,4HP82@91061	NA|NA|NA	S	Domain of unknown function (DUF4430)
NHHNPPIF_00623	322159.STER_0760	0.0	1807.3	Bacilli	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000			iJN678.ppc,iSFV_1184.SFV_4025	Bacteria	1TQB6@1239,4HCAF@91061,COG2352@1,COG2352@2	NA|NA|NA	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NHHNPPIF_00624	264199.stu0719	2.4e-184	651.4	Bacilli	holA		2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1TRM0@1239,4HBB4@91061,COG1466@1,COG1466@2	NA|NA|NA	L	DNA polymerase III delta subunit
NHHNPPIF_00625	322159.STER_0762	8.5e-113	412.9	Bacilli	sodA	GO:0005575,GO:0005576	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016				ko00000,ko00001,ko01000				Bacteria	1TPXT@1239,4HA6U@91061,COG0605@1,COG0605@2	NA|NA|NA	C	radicals which are normally produced within the cells and which are toxic to biological systems
NHHNPPIF_00626	1069533.Sinf_0020	5.3e-21	106.3	Firmicutes													Bacteria	1TQ93@1239,COG3464@1,COG3464@2	NA|NA|NA	L	Transposase
NHHNPPIF_00627	1069533.Sinf_0729	4.2e-192	677.2	Bacilli	wbbI	GO:0003674,GO:0003824,GO:0008194,GO:0008378,GO:0008921,GO:0016740,GO:0016757,GO:0016758,GO:0035250										iAF1260.b2034,iBWG_1329.BWG_1824,iECDH10B_1368.ECDH10B_2184,iECDH1ME8569_1439.ECDH1ME8569_1971,iECSF_1327.ECSF_1923,iEcDH1_1363.EcDH1_1623,iJO1366.b2034,iY75_1357.Y75_RS10645	Bacteria	1UZFG@1239,4ISTK@91061,COG0438@1,COG0438@2	NA|NA|NA	M	transferase activity, transferring glycosyl groups
NHHNPPIF_00628	1069533.Sinf_0727	1e-212	745.7	Bacilli	glf	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0071554,GO:0071766,GO:0071840,GO:0071944,GO:0097159,GO:1901265,GO:1901363	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520		R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000			iNJ661.Rv3809c	Bacteria	1TQB9@1239,4HB5F@91061,COG0562@1,COG0562@2	NA|NA|NA	M	UDP-galactopyranose mutase
NHHNPPIF_00629	904306.HMPREF9192_1685	5.4e-243	846.7	Bacilli	epsU												Bacteria	1TP7R@1239,4HC84@91061,COG2244@1,COG2244@2	NA|NA|NA	S	Polysaccharide biosynthesis protein
NHHNPPIF_00630	862970.SAIN_1720	6.3e-173	613.6	Bacilli													Bacteria	1VC7Z@1239,2BVGB@1,32U6R@2,4HNDJ@91061	NA|NA|NA		
NHHNPPIF_00631	862970.SAIN_1721	7.1e-149	533.5	Bacilli													Bacteria	1V0TF@1239,4HN74@91061,COG1215@1,COG1215@2	NA|NA|NA	M	Glycosyltransferase like family 2
NHHNPPIF_00632	862970.SAIN_1722	8.6e-123	446.8	Bacilli													Bacteria	1V0TF@1239,4ISVG@91061,COG1215@1,COG1215@2	NA|NA|NA	M	Glycosyltransferase, group 2 family protein
NHHNPPIF_00634	904306.HMPREF9192_1681	4.6e-73	280.4	Bacilli	Z012_10770												Bacteria	1V8R9@1239,4HW77@91061,COG3955@1,COG3955@2	NA|NA|NA	M	Domain of unknown function (DUF1919)
NHHNPPIF_00635	1116231.SMA_0863	4.3e-206	723.8	Bacilli	wcoF												Bacteria	1TR6R@1239,4HEIZ@91061,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyltransferase, group 1 family protein
NHHNPPIF_00636	904306.HMPREF9192_1679	5e-218	763.5	Bacilli	rgpAc			ko:K12996					ko00000,ko01000,ko01003,ko01005		GT4		Bacteria	1TR0Y@1239,4IPU2@91061,COG0438@1,COG0438@2	NA|NA|NA	M	group 1 family protein
NHHNPPIF_00637	264199.stu1108	1e-251	875.5	Bacilli	cpsE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944											Bacteria	1TP7M@1239,4HB3Z@91061,COG2148@1,COG2148@2	NA|NA|NA	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
NHHNPPIF_00638	322159.STER_1068	2.5e-114	418.3	Bacilli	cpsD												Bacteria	1TS4R@1239,4HCEN@91061,COG0489@1,COG0489@2	NA|NA|NA	D	COG0489 ATPases involved in chromosome partitioning
NHHNPPIF_00639	1046629.Ssal_01180	1.7e-109	402.1	Bacilli	cps4C												Bacteria	1UZCR@1239,4HE26@91061,COG3944@1,COG3944@2	NA|NA|NA	M	biosynthesis protein
NHHNPPIF_00640	322159.STER_1070	1.9e-135	488.4	Bacilli	cpsB		3.1.3.48	ko:K01104					ko00000,ko01000				Bacteria	1TQ1T@1239,4HDZR@91061,COG4464@1,COG4464@2	NA|NA|NA	GM	Capsular polysaccharide biosynthesis protein
NHHNPPIF_00641	322159.STER_1071	2.1e-250	871.3	Bacilli	cps4A												Bacteria	1TR1B@1239,4HDRS@91061,COG1316@1,COG1316@2	NA|NA|NA	K	Cell envelope-like function transcriptional attenuator common domain protein
NHHNPPIF_00642	322159.STER_1072	4.9e-128	463.8	Bacilli	deoD	GO:0003674,GO:0003824,GO:0004731,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006152,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009164,GO:0009987,GO:0015949,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0019686,GO:0033554,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658	2.4.2.1,2.4.2.28	ko:K00772,ko:K03784	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000			iAPECO1_1312.APECO1_1997,iB21_1397.B21_04226,iE2348C_1286.E2348C_4682,iEC042_1314.EC042_4881,iECABU_c1320.ECABU_c50190,iECBD_1354.ECBD_3636,iECB_1328.ECB_04260,iECD_1391.ECD_04260,iECED1_1282.ECED1_5255,iECIAI39_1322.ECIAI39_4916,iECNA114_1301.ECNA114_4626,iECO26_1355.ECO26_5590,iECOK1_1307.ECOK1_4950,iECP_1309.ECP_4768,iEcolC_1368.EcolC_3672,iLF82_1304.LF82_0467,iNRG857_1313.NRG857_22170,iPC815.YPO0440,iSFV_1184.SFV_4418,iSF_1195.SF4416,iSFxv_1172.SFxv_4809,iS_1188.S4687,iUMN146_1321.UM146_22680,iUMNK88_1353.UMNK88_5303,iUTI89_1310.UTI89_C5155,ic_1306.c5468	Bacteria	1TQPG@1239,4HADM@91061,COG0813@1,COG0813@2	NA|NA|NA	F	purine nucleoside phosphorylase
NHHNPPIF_00643	904306.HMPREF9192_1673	7e-38	162.9	Bacilli	yfeJ		6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002				Bacteria	1V97T@1239,4HIKV@91061,COG0518@1,COG0518@2	NA|NA|NA	F	glutamine amidotransferase
NHHNPPIF_00644	904306.HMPREF9192_1673	3.7e-67	260.8	Bacilli	yfeJ		6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002				Bacteria	1V97T@1239,4HIKV@91061,COG0518@1,COG0518@2	NA|NA|NA	F	glutamine amidotransferase
NHHNPPIF_00645	904306.HMPREF9192_1672	9e-88	329.7	Firmicutes	clcA_2			ko:K03281					ko00000	2.A.49			Bacteria	1V07H@1239,COG0038@1,COG0038@2	NA|NA|NA	P	chloride
NHHNPPIF_00646	322159.STER_1075	4e-150	537.3	Bacilli	punA		2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110		R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000				Bacteria	1TQ37@1239,4HABP@91061,COG0005@1,COG0005@2	NA|NA|NA	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NHHNPPIF_00647	264199.stu1118	8.1e-41	172.6	Bacteria													Bacteria	COG3797@1,COG3797@2	NA|NA|NA	S	Protein of unknown function (DUF1697)
NHHNPPIF_00648	322159.STER_1077	3.8e-237	827.0	Bacilli	deoB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008973,GO:0016853,GO:0016866,GO:0016868,GO:0044424,GO:0044444,GO:0044464	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230		R01057,R02749	RC00408	ko00000,ko00001,ko01000				Bacteria	1TP70@1239,4H9RU@91061,COG1015@1,COG1015@2	NA|NA|NA	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NHHNPPIF_00649	264199.stu1121	5e-122	443.7	Bacilli	rpiA	GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	2.7.1.12,2.7.1.15,5.3.1.6	ko:K00851,ko:K00852,ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01051,R01056,R01737,R02750	RC00002,RC00017,RC00434	ko00000,ko00001,ko00002,ko01000				Bacteria	1V1DB@1239,4HFQ7@91061,COG0120@1,COG0120@2	NA|NA|NA	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NHHNPPIF_00651	1316408.HSISM1_134	5.7e-08	62.8	Bacilli													Bacteria	1VU2V@1239,4HU5W@91061,COG3266@1,COG3266@2	NA|NA|NA	V	Glucan-binding protein C
NHHNPPIF_00652	435842.HMPREF0848_00593	2.7e-22	111.3	Bacilli													Bacteria	1VU2V@1239,4HU5W@91061,COG3266@1,COG3266@2	NA|NA|NA	V	Glucan-binding protein C
NHHNPPIF_00653	322159.STER_1082	2.4e-112	411.4	Bacilli	ung2		3.2.2.27	ko:K21929	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	1V1F8@1239,4HFVS@91061,COG1573@1,COG1573@2	NA|NA|NA	L	Uracil-DNA glycosylase
NHHNPPIF_00654	264199.stu1127	9e-275	952.2	Bacilli	pepV		3.5.1.18	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	M00016	R00899,R02734,R04951	RC00064,RC00090,RC00096,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002				Bacteria	1TPEG@1239,4HC14@91061,COG0624@1,COG0624@2	NA|NA|NA	E	Dipeptidase
NHHNPPIF_00655	264199.stu1128	6.4e-27	125.9	Bacilli	dmpI	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000				Bacteria	1VKD5@1239,4HRBS@91061,COG1942@1,COG1942@2	NA|NA|NA	G	Belongs to the 4-oxalocrotonate tautomerase family
NHHNPPIF_00656	264199.stu1129	2e-41	174.9	Bacilli	XK27_03610												Bacteria	1V77V@1239,4HKYX@91061,COG0454@1,COG0456@2	NA|NA|NA	K	Gnat family
NHHNPPIF_00657	322159.STER_1786	1e-33	148.7	Bacilli				ko:K07491					ko00000				Bacteria	1V1CM@1239,4HGN6@91061,COG1943@1,COG1943@2	NA|NA|NA	L	Transposase
NHHNPPIF_00658	1069533.Sinf_0806	3.3e-68	264.2	Bacteria				ko:K07497					ko00000				Bacteria	COG2801@1,COG2801@2	NA|NA|NA	L	transposition
NHHNPPIF_00659	873447.SPB_0385	8.5e-275	952.6	Bacilli	topB		5.99.1.2	ko:K03169					ko00000,ko01000,ko03032				Bacteria	1TPJD@1239,4HAZV@91061,COG0550@1,COG0550@2	NA|NA|NA	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NHHNPPIF_00660	1035184.HMPREF1042_2335	0.0	1153.3	Streptococcus anginosus group													Bacteria	1TQN4@1239,42DXU@671232,4HN8F@91061,COG0358@1,COG0358@2,COG4227@1,COG4227@2	NA|NA|NA	L	Toprim-like
NHHNPPIF_00662	873447.SPB_0388	3.3e-35	154.5	Bacilli													Bacteria	1VJAY@1239,2DPAH@1,3318H@2,4HR0E@91061	NA|NA|NA	S	Bacterial mobilisation protein (MobC)
NHHNPPIF_00663	322159.STER_0685	1.3e-24	118.2	Firmicutes	WQ51_00785												Bacteria	1W67C@1239,2FKS5@1,34CCP@2	NA|NA|NA		
NHHNPPIF_00664	264199.stu0636	0.0	1387.9	Bacilli	ltaS	GO:0005575,GO:0005576	2.7.8.20	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100		R05081,R10849	RC00017	ko00000,ko00001,ko01000				Bacteria	1TRMA@1239,4H9S0@91061,COG1368@1,COG1368@2	NA|NA|NA	M	Belongs to the LTA synthase family
NHHNPPIF_00665	264199.stu0637	2.6e-219	767.7	Bacilli	ywbD		2.1.1.191	ko:K06969					ko00000,ko01000,ko03009				Bacteria	1TRAJ@1239,4HAA1@91061,COG1092@1,COG1092@2	NA|NA|NA	J	Methyltransferase
NHHNPPIF_00666	322159.STER_0688	8.6e-122	443.0	Bacilli	aroD	GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25,4.2.1.10	ko:K03785,ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413,R03084	RC00206,RC00848	ko00000,ko00001,ko00002,ko01000				Bacteria	1VHVX@1239,4IPJP@91061,COG0710@1,COG0710@2	NA|NA|NA	E	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NHHNPPIF_00667	322159.STER_0689	1.5e-160	572.0	Bacilli	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQRY@1239,4HD4R@91061,COG0169@1,COG0169@2	NA|NA|NA	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NHHNPPIF_00668	322159.STER_0690	1.9e-200	704.9	Bacilli	aroB		2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPKZ@1239,4HAKN@91061,COG0337@1,COG0337@2	NA|NA|NA	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NHHNPPIF_00669	264199.stu0641	4.5e-219	766.9	Bacilli	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_0976,iNJ661.Rv2540c	Bacteria	1TQ40@1239,4HA0H@91061,COG0082@1,COG0082@2	NA|NA|NA	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NHHNPPIF_00670	322159.STER_0692	1.4e-206	725.3	Bacilli	tyrA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.3.1.12,1.3.1.43	ko:K00210,ko:K00220,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025,M00040	R00732,R01728	RC00125	ko00000,ko00001,ko00002,ko01000			iYO844.BSU22610	Bacteria	1TPXG@1239,4HBI4@91061,COG0287@1,COG0287@2	NA|NA|NA	E	prephenate dehydrogenase
NHHNPPIF_00671	264199.stu0643	3.2e-53	214.2	Bacilli	yheA												Bacteria	1VASS@1239,4HPJM@91061,COG3679@1,COG3679@2	NA|NA|NA	S	Belongs to the UPF0342 family
NHHNPPIF_00672	264199.stu0644	8.8e-173	612.8	Bacilli	ldh		1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922		R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147				Bacteria	1UXY2@1239,4HD1S@91061,COG0039@1,COG0039@2	NA|NA|NA	C	Belongs to the LDH MDH superfamily
NHHNPPIF_00673	264199.stu0645	8.3e-235	819.3	Bacilli	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	1.3.1.12,1.3.1.43,2.5.1.19	ko:K00210,ko:K00220,ko:K00800	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00022,M00025,M00040	R00732,R01728,R03460	RC00125,RC00350	ko00000,ko00001,ko00002,ko01000			iLJ478.TM0345	Bacteria	1TPIH@1239,4HBHZ@91061,COG0128@1,COG0128@2	NA|NA|NA	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NHHNPPIF_00674	322159.STER_0696	2.5e-86	324.7	Bacilli	aroK	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019438,GO:0019632,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615	1.1.1.25,2.7.1.71,4.2.1.10,4.2.3.4	ko:K00014,ko:K00891,ko:K03785,ko:K03786,ko:K13829,ko:K15546	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R02413,R03083,R03084	RC00002,RC00078,RC00206,RC00847,RC00848	ko00000,ko00001,ko00002,ko01000,ko03000			iAPECO1_1312.APECO1_1620,iECOK1_1307.ECOK1_0367,iECS88_1305.ECS88_0383,iUMN146_1321.UM146_15425,iUTI89_1310.UTI89_C0407,iYL1228.KPN_00332	Bacteria	1VA6Z@1239,4HKD6@91061,COG0703@1,COG0703@2	NA|NA|NA	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NHHNPPIF_00675	264199.stu0647	2.5e-152	544.7	Bacilli	pheA	GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000			iYO844.BSU27900	Bacteria	1TPDN@1239,4HA96@91061,COG0077@1,COG0077@2	NA|NA|NA	E	Prephenate dehydratase
NHHNPPIF_00676	322159.STER_0698	9e-238	829.3	Bacilli	msrR												Bacteria	1TSWQ@1239,4HE66@91061,COG1316@1,COG1316@2	NA|NA|NA	K	Transcriptional regulator
NHHNPPIF_00677	1069533.Sinf_0933	1.6e-155	555.4	Bacteria	ydiA			ko:K03304,ko:K11041	ko05150,map05150				ko00000,ko00001,ko02000,ko02042	2.A.16,2.A.16.1			Bacteria	COG1275@1,COG1275@2	NA|NA|NA	P	C4-dicarboxylate transporter malic acid transport protein
NHHNPPIF_00678	322159.STER_0700	1.3e-201	708.8	Bacilli													Bacteria	1UYHK@1239,4HCT5@91061,COG1960@1,COG1960@2	NA|NA|NA	I	acyl-CoA dehydrogenase
NHHNPPIF_00679	322159.STER_0701	4.5e-97	360.5	Bacteria	mip												Bacteria	COG2128@1,COG2128@2	NA|NA|NA	S	hydroperoxide reductase activity
NHHNPPIF_00680	1046629.Ssal_01495	1e-251	875.5	Bacilli	rumA	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.190	ko:K03215					ko00000,ko01000,ko03009				Bacteria	1TP4H@1239,4HA6M@91061,COG2265@1,COG2265@2	NA|NA|NA	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHHNPPIF_00681	638301.HMPREF0444_1318	1.7e-54	218.4	Carnobacteriaceae													Bacteria	1V1G4@1239,27HT6@186828,4HI02@91061,COG1670@1,COG1670@2	NA|NA|NA	J	Acetyltransferase (GNAT) domain
NHHNPPIF_00682	638301.HMPREF0444_1312	5.7e-95	353.6	Bacilli													Bacteria	1V2YZ@1239,2DBDH@1,2Z8KQ@2,4HK4W@91061	NA|NA|NA		
NHHNPPIF_00683	272623.L172704	1.9e-59	235.0	Lactococcus													Bacteria	1W16R@1239,1YCF5@1357,2FHJA@1,349D7@2,4HYIT@91061	NA|NA|NA	S	Uncharacterised lipoprotein family
NHHNPPIF_00684	272623.L173469	1.5e-75	288.9	Lactococcus	tspO			ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166				ko00000,ko00001,ko02000	9.A.24			Bacteria	1V896@1239,1YCDJ@1357,4HK1B@91061,COG3476@1,COG3476@2	NA|NA|NA	T	TspO/MBR family
NHHNPPIF_00685	1046629.Ssal_00974	2.6e-44	184.5	Bacilli	pepD			ko:K08659					ko00000,ko01000,ko01002				Bacteria	1TQ0F@1239,4HC3G@91061,COG4690@1,COG4690@2	NA|NA|NA	E	Dipeptidase
NHHNPPIF_00686	904306.HMPREF9192_1264	1.2e-103	382.5	Bacilli	pepD			ko:K08659					ko00000,ko01000,ko01002				Bacteria	1TQ0F@1239,4HC3G@91061,COG4690@1,COG4690@2	NA|NA|NA	E	Dipeptidase
NHHNPPIF_00687	264199.stu0833	1.9e-161	575.1	Bacilli	whiA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944		ko:K09762					ko00000				Bacteria	1TP2X@1239,4HB4H@91061,COG1481@1,COG1481@2	NA|NA|NA	K	May be required for sporulation
NHHNPPIF_00688	322159.STER_0876	3.6e-182	644.0	Bacilli	ybhK												Bacteria	1TPNV@1239,4HA0Z@91061,COG0391@1,COG0391@2	NA|NA|NA	S	Required for morphogenesis under gluconeogenic growth conditions
NHHNPPIF_00689	264199.stu0831	4.5e-163	580.5	Bacilli	rapZ	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363		ko:K06958					ko00000,ko03019				Bacteria	1TPS4@1239,4H9KM@91061,COG1660@1,COG1660@2	NA|NA|NA	S	Displays ATPase and GTPase activities
NHHNPPIF_00690	322159.STER_0874	1.5e-135	488.8	Bacilli	yejC												Bacteria	1V46X@1239,4HI49@91061,COG4420@1,COG4420@2	NA|NA|NA	S	cyclic nucleotide-binding protein
NHHNPPIF_00691	1046629.Ssal_00969	4.2e-18	96.7	Bacteria													Bacteria	COG1196@1,COG1196@2	NA|NA|NA	D	nuclear chromosome segregation
NHHNPPIF_00692	264199.stu1512	1.2e-157	562.8	Bacilli				ko:K06871					ko00000				Bacteria	1TQPS@1239,4HCKJ@91061,COG0641@1,COG0641@2	NA|NA|NA	C	Arylsulfatase regulator (Fe-S oxidoreductase)
NHHNPPIF_00693	467705.SGO_1358	1.1e-196	693.0	Bacteria				ko:K06147,ko:K06148					ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21			Bacteria	COG1132@1,COG1132@2	NA|NA|NA	V	(ABC) transporter
NHHNPPIF_00694	1046629.Ssal_00659	1.7e-51	208.4	Bacilli			2.3.1.128	ko:K03789					ko00000,ko01000,ko03009				Bacteria	1VEW7@1239,4HPE4@91061,COG0454@1,COG0456@2	NA|NA|NA	K	Acetyltransferase GNAT Family
NHHNPPIF_00695	1046629.Ssal_00660	1.4e-273	948.3	Bacilli													Bacteria	1VBKU@1239,2DI63@1,32UAI@2,4HUJH@91061	NA|NA|NA	S	Protein of unknown function (DUF3114)
NHHNPPIF_00697	264199.stu1413	0.0	1508.0	Bacilli	gshF		6.3.2.2,6.3.2.29,6.3.2.30,6.3.2.4	ko:K01919,ko:K01921,ko:K03802,ko:K16786,ko:K16787	ko00270,ko00473,ko00480,ko00550,ko01100,ko01502,ko02010,map00270,map00473,map00480,map00550,map01100,map01502,map02010	M00118,M00582	R00894,R01150,R10993	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35			Bacteria	1TPGX@1239,4HAMJ@91061,COG1181@1,COG1181@2,COG2918@1,COG2918@2	NA|NA|NA	H	Belongs to the glutamate--cysteine ligase type 1 family
NHHNPPIF_00698	264199.stu1412	2.1e-39	167.9	Bacteria				ko:K18996,ko:K19171					ko00000,ko02048,ko03032				Bacteria	COG1132@1,COG1132@2	NA|NA|NA	V	(ABC) transporter
NHHNPPIF_00699	904306.HMPREF9192_0999	3.6e-100	370.9	Bacilli				ko:K06147					ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21			Bacteria	1TP0B@1239,4HA3S@91061,COG1132@1,COG1132@2	NA|NA|NA	V	abc transporter atp-binding protein
NHHNPPIF_00700	904306.HMPREF9192_1001	3.6e-258	897.1	Bacilli	zmpB	GO:0005575,GO:0005618,GO:0005623,GO:0009986,GO:0016020,GO:0030312,GO:0044464,GO:0071944		ko:K08643					ko00000,ko01000,ko01002				Bacteria	1UJ29@1239,4IT10@91061,COG3064@1,COG3064@2	NA|NA|NA	M	M26 IgA1-specific Metallo-endopeptidase C-terminal region
NHHNPPIF_00701	264199.stu1405	6.7e-24	115.9	Bacteria				ko:K07497					ko00000				Bacteria	COG2801@1,COG2801@2	NA|NA|NA	L	transposition
NHHNPPIF_00702	264199.stu0038	1.2e-08	64.3	Firmicutes				ko:K07497					ko00000				Bacteria	1TQQY@1239,COG2801@1,COG2801@2	NA|NA|NA	L	Integrase core domain protein
NHHNPPIF_00703	264199.stu1403	2.3e-150	538.1	Bacilli	galR			ko:K02529					ko00000,ko03000				Bacteria	1TPZJ@1239,4HC9Z@91061,COG1609@1,COG1609@2	NA|NA|NA	K	Transcriptional regulator
NHHNPPIF_00704	904306.HMPREF9192_1002	1.7e-21	108.2	Bacilli	galR			ko:K02529					ko00000,ko03000				Bacteria	1TPZJ@1239,4HC9Z@91061,COG1609@1,COG1609@2	NA|NA|NA	K	Transcriptional regulator
NHHNPPIF_00705	322159.STER_1371	2e-219	768.1	Bacilli	galK	GO:0005975,GO:0005996,GO:0006012,GO:0008150,GO:0008152,GO:0019318,GO:0044238,GO:0044281,GO:0071704	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1TPD0@1239,4HARP@91061,COG0153@1,COG0153@2	NA|NA|NA	G	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NHHNPPIF_00706	264199.stu1401	2.8e-290	1003.8	Bacilli	galT		2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPBN@1239,4HAYJ@91061,COG4468@1,COG4468@2	NA|NA|NA	G	UDPglucose--hexose-1-phosphate uridylyltransferase
NHHNPPIF_00707	322159.STER_1369	4.3e-194	683.7	Bacilli	galE		5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQ7N@1239,4H9U5@91061,COG1087@1,COG1087@2	NA|NA|NA	M	Belongs to the NAD(P)-dependent epimerase dehydratase family
NHHNPPIF_00708	264199.stu1399	8.7e-198	696.0	Bacilli	galM		5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000				Bacteria	1V5UK@1239,4HTRY@91061,COG2017@1,COG2017@2	NA|NA|NA	G	Catalyzes the interconversion of alpha and beta anomers of maltose
NHHNPPIF_00709	322159.STER_1367	0.0	1183.3	Bacilli	lacS	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K03292,ko:K11104,ko:K16209					ko00000,ko02000	2.A.2,2.A.2.1,2.A.2.2			Bacteria	1TRA5@1239,4HCDS@91061,COG2190@1,COG2190@2,COG2211@1,COG2211@2	NA|NA|NA	G	transporter
NHHNPPIF_00710	264199.stu1397	0.0	2111.3	Bacilli	lacL		3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100		R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000				Bacteria	1TPDC@1239,4HANW@91061,COG3250@1,COG3250@2	NA|NA|NA	G	-beta-galactosidase
NHHNPPIF_00711	264199.stu1395	7.6e-230	802.7	Bacilli	sbcD			ko:K03547					ko00000,ko03400				Bacteria	1TQY6@1239,4HAKB@91061,COG0420@1,COG0420@2	NA|NA|NA	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NHHNPPIF_00712	264199.stu1394	0.0	1419.1	Bacilli	sbcC			ko:K03546					ko00000,ko03400				Bacteria	1TPCS@1239,4H9Q3@91061,COG0419@1,COG0419@2	NA|NA|NA	L	ATPase involved in DNA repair
NHHNPPIF_00713	706433.HMPREF9430_01341	1e-31	143.3	Firmicutes													Bacteria	1V146@1239,28ITE@1,2Z8SB@2	NA|NA|NA		
NHHNPPIF_00714	1403946.Q615_SPAC00123G0004	3.1e-44	184.1	Bacilli				ko:K07483					ko00000				Bacteria	1V9ZX@1239,4HKN9@91061,COG2963@1,COG2963@2	NA|NA|NA	L	COG2963 Transposase and inactivated derivatives
NHHNPPIF_00715	1403946.Q615_SPAC00123G0003	5.9e-62	243.4	Bacilli													Bacteria	1TPEH@1239,4HCHG@91061,COG2801@1,COG2801@2	NA|NA|NA	L	Transposase and inactivated derivatives
NHHNPPIF_00716	1123299.AUKZ01000032_gene1329	1.5e-39	168.3	Bacteria													Bacteria	COG2801@1,COG2801@2	NA|NA|NA	L	transposition
NHHNPPIF_00725	1069533.Sinf_0802	7.4e-115	420.2	Bacilli													Bacteria	1VT9V@1239,4HV77@91061,COG0791@1,COG0791@2	NA|NA|NA	M	Bacteriophage peptidoglycan hydrolase
NHHNPPIF_00726	888049.HMPREF8578_0250	2.8e-22	110.9	Bacilli													Bacteria	1VGGV@1239,4HPNN@91061,COG5546@1,COG5546@2	NA|NA|NA	S	COG5546 Small integral membrane protein
NHHNPPIF_00730	112023.Q9MCJ5_9CAUD	4e-308	1063.5	Caudovirales													Viruses	4QAK6@10239,4QPBY@28883,4QUP9@35237	NA|NA|NA	S	N-acetylmuramoyl-L-alanine amidase activity
NHHNPPIF_00731	306323.Q56S86_9CAUD	0.0	1557.3	Siphoviridae													Viruses	4QAK6@10239,4QKKV@10699,4QPBY@28883,4QUP9@35237	NA|NA|NA	S	peptidoglycan catabolic process
NHHNPPIF_00732	78541.O80180_9CAUD	1.6e-171	609.4	Siphoviridae		GO:0005575,GO:0019012,GO:0044423,GO:0098015											Viruses	4QBF8@10239,4QKN2@10699,4QPI9@28883,4QUS7@35237	NA|NA|NA	S	Phage tail protein
NHHNPPIF_00733	1385385.U6E979_9CAUD	2.6e-193	683.3	Siphoviridae		GO:0005575,GO:0018995,GO:0019012,GO:0030430,GO:0033643,GO:0033646,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217											Viruses	4QAK6@10239,4QKKV@10699,4QPBY@28883,4QUP9@35237	NA|NA|NA	S	peptidoglycan catabolic process
NHHNPPIF_00735	682370.C9W9I6_9CAUD	5e-57	226.9	Siphoviridae													Viruses	4QBPH@10239,4QKQD@10699,4QQHY@28883,4QV0G@35237	NA|NA|NA	S	Pfam:Phage_TAC_12
NHHNPPIF_00736	1385385.U6E9D4_9CAUD	3.4e-75	287.7	Siphoviridae													Viruses	4QAVQ@10239,4QKPR@10699,4QPGB@28883,4QXUP@35237	NA|NA|NA	S	Phage major tail protein 2
NHHNPPIF_00737	306323.Q56S92_9CAUD	8.2e-61	239.6	Siphoviridae		GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019058,GO:0019068,GO:0044403,GO:0044419,GO:0044423,GO:0051704,GO:0098003,GO:0098004,GO:0098015											Viruses	4QB3I@10239,4QKP4@10699,4QPE3@28883	NA|NA|NA		
NHHNPPIF_00738	682370.C9W9I3_9CAUD	4e-43	180.6	Siphoviridae													Viruses	4QB1F@10239,4QKPW@10699,4QPSW@28883,4QUYH@35237	NA|NA|NA	S	exonuclease activity
NHHNPPIF_00740	1123302.KB904182_gene68	2.1e-36	158.3	Firmicutes													Bacteria	1VN9C@1239,2EKJJ@1,33E9D@2	NA|NA|NA	S	Phage gp6-like head-tail connector protein
NHHNPPIF_00742	1385385.U6E9B4_9CAUD	7.6e-178	629.8	Siphoviridae		GO:0005575,GO:0019012,GO:0019028,GO:0019030,GO:0039620,GO:0044423											Viruses	4QB9S@10239,4QM6J@10699,4QPW1@28883,4QUXK@35237	NA|NA|NA	S	Phage major capsid protein E
NHHNPPIF_00743	1123302.KB904182_gene70	2.4e-14	85.1	Firmicutes													Bacteria	1UHM5@1239,2DRYD@1,33DP1@2	NA|NA|NA		
NHHNPPIF_00744	1123315.AUIP01000003_gene242	3.5e-10	72.0	Bacilli													Bacteria	1VNT5@1239,2DS40@1,33EEI@2,4HRSQ@91061	NA|NA|NA	S	Domain of unknown function (DUF4355)
NHHNPPIF_00745	1385385.U6E9F1_9CAUD	1.8e-111	409.1	Siphoviridae		GO:0005575,GO:0019012,GO:0019028,GO:0044423,GO:0046729											Viruses	4QC5Z@10239,4QKMB@10699,4QPGX@28883,4QUNP@35237	NA|NA|NA	S	Phage Mu protein F like protein
NHHNPPIF_00746	682370.C9W9H5_9CAUD	5.3e-249	866.7	Siphoviridae		GO:0005575,GO:0019012,GO:0019028,GO:0032991,GO:0044423,GO:0046729,GO:0046798											Viruses	4QAR7@10239,4QKQ3@10699,4QPKJ@28883,4QUW5@35237	NA|NA|NA	S	Phage portal protein, SPP1 Gp6-like
NHHNPPIF_00747	73422.L0P509_9CAUD	4.9e-240	836.6	Siphoviridae													Viruses	4QMEV@10699	NA|NA|NA	S	Terminase-like family
NHHNPPIF_00748	1054460.SPPN_00130	5.5e-24	117.5	Bacteria				ko:K07474					ko00000				Bacteria	COG3728@1,COG3728@2	NA|NA|NA	L	DNA packaging
NHHNPPIF_00749	173707.Q938L8_9CAUD	1.1e-31	142.9	Siphoviridae													Viruses	4QDP9@10239,4QMYB@10699,4QQY8@28883,4QWR2@35237	NA|NA|NA		
NHHNPPIF_00752	1461246.X2KPG8_9VIRU	3.1e-24	118.2	Viruses													Viruses	4QAXV@10239	NA|NA|NA	S	YopX protein
NHHNPPIF_00754	306323.Q56S64_9CAUD	2.2e-30	138.7	Siphoviridae													Viruses	4QAQV@10239,4QKM5@10699,4QPCB@28883,4QUPK@35237	NA|NA|NA	S	sequence-specific DNA binding
NHHNPPIF_00755	768726.HMPREF9178_1077	2e-30	139.0	Streptococcus mitis													Bacteria	1U4MH@1239,2DKDX@1,2TQ21@28037,3098Q@2,4I04V@91061	NA|NA|NA	S	Protein of unknown function (DUF1642)
NHHNPPIF_00757	1123315.AUIP01000014_gene1938	2.7e-31	142.1	Bacilli													Bacteria	1VMJG@1239,2DS9F@1,33F4A@2,4HSZ4@91061	NA|NA|NA	S	Protein of unknown function (DUF1642)
NHHNPPIF_00760	1123309.AQYB01000014_gene918	3.9e-10	70.1	Bacilli													Bacteria	1TZGK@1239,2BK0S@1,32EDT@2,4HSJ1@91061	NA|NA|NA		
NHHNPPIF_00762	112023.Q9MCM0_9CAUD	3.9e-78	297.4	Siphoviridae													Viruses	4QKQC@10699,4QPK3@28883,4QW7S@35237	NA|NA|NA	S	magnesium ion binding
NHHNPPIF_00763	646413.C5IUI2_9CAUD	6.6e-65	253.4	Siphoviridae													Viruses	4QAU9@10239,4QKUJ@10699,4QQV4@28883,4QVR2@35237	NA|NA|NA	S	Single-strand binding protein family
NHHNPPIF_00764	1239381.K4JU67_9CAUD	8e-49	201.1	Siphoviridae													Viruses	4QB3F@10239,4QM6P@10699,4QPZ0@28883,4QV3C@35237	NA|NA|NA	S	Protein of unknown function (DUF1351)
NHHNPPIF_00765	35344.A0A097PBE8_BPT12	1.1e-33	150.2	Podoviridae													Viruses	4QBFR@10239,4QNJQ@10744,4QPRX@28883,4QV1E@35237	NA|NA|NA	S	ERF superfamily
NHHNPPIF_00767	633135.C9WB96_9CAUD	7.3e-133	479.9	Siphoviridae													Viruses	4QBU2@10239,4QM65@10699,4QPH3@28883,4QV13@35237	NA|NA|NA	S	IstB-like ATP binding protein
NHHNPPIF_00768	1035184.HMPREF1042_1642	2.1e-85	322.4	Streptococcus anginosus group													Bacteria	1TQ65@1239,42EBW@671232,4HMRU@91061,COG3935@1,COG3935@2	NA|NA|NA	L	N-terminal phage replisome organiser (Phage_rep_org_N)
NHHNPPIF_00772	1069533.Sinf_0769	2.3e-25	121.3	Bacilli													Bacteria	1VN2K@1239,2ENNN@1,33GA0@2,4HR9I@91061	NA|NA|NA		
NHHNPPIF_00773	1140002.I570_01470	1.8e-08	66.2	Enterococcaceae													Bacteria	1U0EV@1239,2DJPN@1,306V4@2,4B4ND@81852,4I9SB@91061	NA|NA|NA	S	ORF6C domain
NHHNPPIF_00774	646413.C5IUM1_9CAUD	1.1e-137	496.1	Siphoviridae													Viruses	4QAPQ@10239,4QMUB@10699,4QPWV@28883,4QZ6P@35237	NA|NA|NA		
NHHNPPIF_00775	64186.O21995_9CAUD	2.4e-28	131.0	Siphoviridae													Viruses	4QAQV@10239,4QKM5@10699,4QPCB@28883,4QUPK@35237	NA|NA|NA	S	sequence-specific DNA binding
NHHNPPIF_00776	64186.O21993_9CAUD	7.5e-53	213.0	Siphoviridae													Viruses	4QKM5@10699,4QPCB@28883,4QUPK@35237	NA|NA|NA	S	sequence-specific DNA binding
NHHNPPIF_00777	1095737.HMPREF1110_1192	2.3e-20	105.1	Bacteria													Bacteria	COG2856@1,COG2856@2	NA|NA|NA	E	Zn peptidase
NHHNPPIF_00778	1385385.U6E9C7_9CAUD	1.7e-22	112.5	Siphoviridae													Viruses	4QBN1@10239,4QKN7@10699,4QQWW@28883,4QZ19@35237	NA|NA|NA	S	Host cell surface-exposed lipoprotein
NHHNPPIF_00779	646413.C5IUL7_9CAUD	2.5e-206	724.5	Siphoviridae		GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0015074,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360											Viruses	4QAQE@10239,4QKN9@10699,4QPDM@28883,4QUYF@35237	NA|NA|NA	S	Phage integrase family
NHHNPPIF_00780	1046629.Ssal_01521	8.2e-246	855.9	Bacilli	eno	GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0009986,GO:0016829,GO:0016835,GO:0016836,GO:0019899,GO:0030312,GO:0035375,GO:0043236,GO:0044424,GO:0044464,GO:0044877,GO:0050840,GO:0071944	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147				Bacteria	1TP2S@1239,4HAKI@91061,COG0148@1,COG0148@2	NA|NA|NA	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NHHNPPIF_00781	264199.stu0634	5.7e-77	293.5	Bacilli	yueI												Bacteria	1VFCV@1239,4HNNE@91061,COG5506@1,COG5506@2	NA|NA|NA	S	Protein of unknown function (DUF1694)
NHHNPPIF_00782	322159.STER_0682	2.9e-207	727.6	Firmicutes	glxK		2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130		R08572	RC00002,RC00428	ko00000,ko00001,ko01000				Bacteria	1TPSI@1239,COG1929@1,COG1929@2	NA|NA|NA	G	Belongs to the glycerate kinase type-1 family
NHHNPPIF_00783	322159.STER_0681	5.9e-45	186.4	Bacteria	yyaQ												Bacteria	COG2315@1,COG2315@2	NA|NA|NA	V	Protein conserved in bacteria
NHHNPPIF_00784	904306.HMPREF9192_1362	5.2e-27	126.3	Bacilli	yyaQ												Bacteria	1V4K7@1239,4HP2K@91061,COG2315@1,COG2315@2	NA|NA|NA	S	YjbR
NHHNPPIF_00785	322159.STER_0679	9.9e-183	646.0	Bacilli	ccpA	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141		ko:K02529					ko00000,ko03000				Bacteria	1TQ7K@1239,4H9NG@91061,COG1609@1,COG1609@2	NA|NA|NA	K	Catabolite control protein A
NHHNPPIF_00786	264199.stu0629	3.5e-210	737.3	Bacilli	pepQ		3.4.13.9	ko:K01271					ko00000,ko01000,ko01002				Bacteria	1TQ6R@1239,4HA5I@91061,COG0006@1,COG0006@2	NA|NA|NA	E	Belongs to the peptidase M24B family
NHHNPPIF_00787	264199.stu0628	1.7e-63	248.4	Bacilli	yugI		5.3.1.9	ko:K01810,ko:K02945,ko:K07570,ko:K07571,ko:K19142	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko03010,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map03010	M00001,M00004,M00114,M00178	R02739,R02740,R03321	RC00376,RC00563	br01610,ko00000,ko00001,ko00002,ko01000,ko02048,ko03011,ko04147				Bacteria	1VASQ@1239,4HKSW@91061,COG1098@1,COG1098@2	NA|NA|NA	J	RNA binding protein, contains ribosomal protein S1 domain
NHHNPPIF_00788	322159.STER_0676	2.1e-276	957.6	Bacilli	ppiB	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217				ko00000,ko00001,ko01000,ko03110,ko04147				Bacteria	1TRHW@1239,4H9V0@91061,COG0561@1,COG0561@2,COG0652@1,COG0652@2	NA|NA|NA	G	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NHHNPPIF_00789	264199.stu0626	1.1e-80	305.8	Bacilli	smpB	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564		ko:K03664					ko00000				Bacteria	1V3IJ@1239,4HGZX@91061,COG0691@1,COG0691@2	NA|NA|NA	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NHHNPPIF_00790	264199.stu0625	0.0	1493.0	Bacilli	rnr			ko:K12573,ko:K12585	ko03018,map03018	M00391			ko00000,ko00001,ko00002,ko01000,ko03016,ko03019				Bacteria	1TQ1G@1239,4HBBH@91061,COG0557@1,COG0557@2	NA|NA|NA	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NHHNPPIF_00791	322159.STER_0673	2.6e-33	147.5	Bacilli	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680		ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2			Bacteria	1VEQR@1239,4HNKC@91061,COG1314@1,COG1314@2	NA|NA|NA	U	Preprotein translocase subunit SecG
NHHNPPIF_00792	264199.stu0622	9.4e-220	769.2	Bacilli	mdtG	GO:0006810,GO:0006855,GO:0008150,GO:0015893,GO:0042221,GO:0042493,GO:0050896,GO:0051179,GO:0051234,GO:0055085		ko:K08161					ko00000,ko02000	2.A.1.2.20			Bacteria	1TRDJ@1239,4H9Q9@91061,COG0477@1,COG2814@2	NA|NA|NA	EGP	Major facilitator Superfamily
NHHNPPIF_00793	264199.stu0621	1.3e-105	389.0	Bacilli	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24,3.2.2.23,4.2.99.18	ko:K00859,ko:K08309,ko:K10563	ko00770,ko01100,ko03410,map00770,map01100,map03410	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01011,ko03400		GH23	iIT341.HP0831	Bacteria	1V6FS@1239,4HII3@91061,COG0237@1,COG0237@2	NA|NA|NA	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NHHNPPIF_00794	264199.stu0620	1.2e-154	552.4	Bacilli	fpg		3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	1TPM9@1239,4H9Q7@91061,COG0266@1,COG0266@2	NA|NA|NA	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NHHNPPIF_00795	264199.stu0619	1.3e-165	589.0	Bacilli	era	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113		ko:K03595,ko:K06883					ko00000,ko03009,ko03029				Bacteria	1TP3R@1239,4H9WF@91061,COG1159@1,COG1159@2	NA|NA|NA	M	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NHHNPPIF_00796	264199.stu0618	1.7e-64	251.9	Bacilli	dgkA		2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231		R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000			iAF987.Gmet_2369,iSB619.SA_RS07900	Bacteria	1VEGR@1239,4HNKN@91061,COG0818@1,COG0818@2	NA|NA|NA	M	Diacylglycerol kinase
NHHNPPIF_00797	264199.stu0617	1.3e-87	328.9	Bacilli	ybeY	GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141	2.6.99.2,3.5.4.5	ko:K01489,ko:K03474,ko:K03595,ko:K07042	ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100	M00124	R01878,R02485,R05838,R08221	RC00074,RC00514,RC01476	ko00000,ko00001,ko00002,ko01000,ko03009,ko03029				Bacteria	1V6BU@1239,4HIIE@91061,COG0319@1,COG0319@2	NA|NA|NA	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NHHNPPIF_00798	904306.HMPREF9192_1347	1.8e-64	251.9	Bacilli	licT			ko:K02538,ko:K03488					ko00000,ko03000				Bacteria	1TT5A@1239,4HC5Y@91061,COG3711@1,COG3711@2	NA|NA|NA	K	antiterminator
NHHNPPIF_00799	264199.stu0615	1.1e-43	182.6	Bacteria	licT			ko:K02538,ko:K03488					ko00000,ko03000				Bacteria	COG3711@1,COG3711@2	NA|NA|NA	K	transcriptional antiterminator
NHHNPPIF_00800	264199.stu0614	2.2e-105	388.3	Bacilli	recR	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576		ko:K06187	ko03440,map03440				ko00000,ko00001,ko03400				Bacteria	1TR87@1239,4HAZR@91061,COG0353@1,COG0353@2	NA|NA|NA	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NHHNPPIF_00801	264199.stu0613	0.0	1246.5	Bacilli	pbp2b		3.4.16.4	ko:K00687,ko:K05515,ko:K12553,ko:K21465	ko00550,ko01100,ko01501,map00550,map01100,map01501				ko00000,ko00001,ko01000,ko01011				Bacteria	1TQHY@1239,4HAFX@91061,COG0768@1,COG0768@2	NA|NA|NA	M	penicillin-binding protein
NHHNPPIF_00802	322159.STER_0661	3.9e-148	530.8	Bacilli	nnrD		4.2.1.136,5.1.99.6	ko:K17758,ko:K17759					ko00000,ko01000				Bacteria	1TNZE@1239,4HBZC@91061,COG0063@1,COG0063@2	NA|NA|NA	H	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NHHNPPIF_00803	322159.STER_0660	4.6e-157	560.5	Bacilli	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP1P@1239,4H9Q6@91061,COG0190@1,COG0190@2	NA|NA|NA	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NHHNPPIF_00804	1046629.Ssal_01547	1.5e-23	114.8	Bacilli													Bacteria	1V37Y@1239,4ITDD@91061,COG2267@1,COG2267@2	NA|NA|NA	I	Alpha/beta hydrolase family
NHHNPPIF_00805	264199.stu0609	1.9e-33	147.9	Bacteria	yugF	GO:0003674,GO:0003824,GO:0016787											Bacteria	COG2267@1,COG2267@2	NA|NA|NA	I	carboxylic ester hydrolase activity
NHHNPPIF_00806	663952.SDD27957_07575	1.5e-07	61.2	Streptococcus dysgalactiae group													Bacteria	1MA5P@119603,1TXF8@1239,2DJ8A@1,304YV@2,4I6DK@91061	NA|NA|NA		
NHHNPPIF_00807	264199.stu0608	0.0	1359.7	Bacilli	feoB			ko:K04759					ko00000,ko02000	9.A.8.1			Bacteria	1TP7E@1239,4HBCS@91061,COG0370@1,COG0370@2	NA|NA|NA	P	transporter of a GTP-driven Fe(2 ) uptake system
NHHNPPIF_00808	264199.stu0607	1.2e-77	295.8	Bacilli	feoA			ko:K04758					ko00000,ko02000				Bacteria	1VEHC@1239,4HPFS@91061,COG1918@1,COG1918@2	NA|NA|NA	P	FeoA domain protein
NHHNPPIF_00809	264199.stu0606	1.1e-130	472.6	Bacilli	glnQ		3.6.3.21	ko:K02028		M00236			ko00000,ko00002,ko01000,ko02000	3.A.1.3			Bacteria	1TNYD@1239,4H9WY@91061,COG1126@1,COG1126@2	NA|NA|NA	E	abc transporter atp-binding protein
NHHNPPIF_00810	264199.stu0605	7.5e-118	429.9	Bacilli	WQ51_01820			ko:K02029,ko:K02030,ko:K10040,ko:K17073,ko:K17074	ko02010,map02010	M00228,M00236,M00589			ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.20			Bacteria	1TPM3@1239,4IQKK@91061,COG0765@1,COG0765@2	NA|NA|NA	P	Binding-protein-dependent transport system inner membrane component
NHHNPPIF_00811	264199.stu0604	1.3e-34	151.8	Bacilli	ykuJ												Bacteria	1VKD0@1239,4HRGC@91061,COG4703@1,COG4703@2	NA|NA|NA	S	protein conserved in bacteria
NHHNPPIF_00812	264199.stu0603	3.1e-181	641.0	Bacilli	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPF2@1239,4H9X8@91061,COG0078@1,COG0078@2	NA|NA|NA	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NHHNPPIF_00813	264199.stu0602	0.0	1313.1	Bacilli	clpE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K03697					ko00000,ko03110				Bacteria	1TPMU@1239,4HA0V@91061,COG0542@1,COG0542@2	NA|NA|NA	O	Belongs to the ClpA ClpB family
NHHNPPIF_00814	322159.STER_0647	5.7e-85	320.1	Bacilli	mutT		3.5.4.33,3.6.1.13,3.6.1.55	ko:K01515,ko:K03574,ko:K11991	ko00230,map00230		R01054,R10223	RC00002,RC00477	ko00000,ko00001,ko01000,ko03016,ko03400				Bacteria	1VH6Q@1239,4HQVJ@91061,COG0494@1,COG0494@2	NA|NA|NA	L	Belongs to the Nudix hydrolase family
NHHNPPIF_00815	1046629.Ssal_01559	2.4e-47	194.5	Bacilli	XK27_09445												Bacteria	1VFRS@1239,2EBZ8@1,335YI@2,4HNUK@91061	NA|NA|NA	S	Domain of unknown function (DUF1827)
NHHNPPIF_00816	264199.stu0599	1.7e-07	60.5	Bacteria	yvaA		1.1.1.371	ko:K16044	ko00562,ko01120,map00562,map01120		R09954	RC00182	ko00000,ko00001,ko01000				Bacteria	COG0673@1,COG0673@2	NA|NA|NA	S	inositol 2-dehydrogenase activity
NHHNPPIF_00817	435842.HMPREF0848_00232	1.4e-41	175.3	Bacilli				ko:K22230	ko00562,ko01120,map00562,map01120		R09954	RC00182	ko00000,ko00001,ko01000				Bacteria	1TQSS@1239,4HDXF@91061,COG0673@1,COG0673@2	NA|NA|NA	S	oxidoreductase
NHHNPPIF_00818	435842.HMPREF0848_00232	3e-51	207.6	Bacilli				ko:K22230	ko00562,ko01120,map00562,map01120		R09954	RC00182	ko00000,ko00001,ko01000				Bacteria	1TQSS@1239,4HDXF@91061,COG0673@1,COG0673@2	NA|NA|NA	S	oxidoreductase
NHHNPPIF_00819	322159.STER_0644	9.8e-233	812.4	Bacilli	murN		2.3.2.10,2.3.2.16	ko:K05363,ko:K11693,ko:K12554	ko00550,ko01100,map00550,map01100		R08776,R08779,R08780	RC00055,RC00064,RC00096	ko00000,ko00001,ko01000,ko01011				Bacteria	1V181@1239,4HEVU@91061,COG2348@1,COG2348@2	NA|NA|NA	V	FemAB family
NHHNPPIF_00820	1046629.Ssal_01562	2.9e-63	248.1	Bacteria													Bacteria	COG0398@1,COG0398@2	NA|NA|NA	M	Pfam SNARE associated Golgi protein
NHHNPPIF_00821	904306.HMPREF9192_1327	2.6e-101	374.8	Bacilli													Bacteria	1VGN9@1239,2DMIQ@1,32RV1@2,4I0DZ@91061	NA|NA|NA	S	Domain of Unknown Function with PDB structure (DUF3862)
NHHNPPIF_00824	264199.stu0592	1.3e-202	712.2	Bacilli	rpsA		1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011				Bacteria	1TQ9N@1239,4H9PX@91061,COG0539@1,COG0539@2	NA|NA|NA	J	ribosomal protein S1
NHHNPPIF_00827	1035187.HMPREF9959_0525	1.1e-15	89.0	Streptococcus mitis													Bacteria	1U4J6@1239,29N96@1,2TPZ6@28037,30971@2,4IEAX@91061	NA|NA|NA	S	Protein of unknown function (DUF2969)
NHHNPPIF_00828	264199.stu0590	3.4e-199	700.7	Bacilli	ilvE		2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	1TQQI@1239,4HASX@91061,COG0115@1,COG0115@2	NA|NA|NA	E	Aminotransferase
NHHNPPIF_00829	264199.stu0589	0.0	1557.7	Bacilli	parC	GO:0005575,GO:0005622,GO:0005623,GO:0009330,GO:0032991,GO:0044424,GO:0044464	5.99.1.3	ko:K02469,ko:K02621					ko00000,ko01000,ko02048,ko03032,ko03036,ko03400				Bacteria	1TRE7@1239,4HAQB@91061,COG0188@1,COG0188@2	NA|NA|NA	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHHNPPIF_00830	322159.STER_0633	0.0	1228.8	Bacilli	parE	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034335,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.3	ko:K02470,ko:K02622					ko00000,ko01000,ko02048,ko03032,ko03036,ko03400				Bacteria	1TQCF@1239,4H9UC@91061,COG0187@1,COG0187@2	NA|NA|NA	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHHNPPIF_00831	322159.STER_0632	1.6e-101	375.6	Bacilli	plsY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.3.1.15,3.5.1.104	ko:K08591,ko:K22278	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	1VA3J@1239,4HC55@91061,COG0344@1,COG0344@2	NA|NA|NA	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NHHNPPIF_00832	759913.SDSE_1678	8.3e-15	86.7	Streptococcus dysgalactiae group													Bacteria	1M9TG@119603,1TXCP@1239,2DJ7H@1,304X7@2,4I6AH@91061	NA|NA|NA	L	Helix-hairpin-helix DNA-binding motif class 1
NHHNPPIF_00833	1035184.HMPREF1042_0385	1.4e-29	135.2	Streptococcus anginosus group													Bacteria	1VYRT@1239,2BXCI@1,346RD@2,42DR8@671232,4HYPP@91061	NA|NA|NA	S	Domain of unknown function (DUF1912)
NHHNPPIF_00834	264199.stu0584	3.4e-177	627.5	Bacilli	mmuM	GO:0003674,GO:0003824,GO:0005488,GO:0006575,GO:0006790,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008270,GO:0008757,GO:0008898,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033477,GO:0033554,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:1901564	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000				Bacteria	1UHQ5@1239,4HAS6@91061,COG2040@1,COG2040@2	NA|NA|NA	H	Homocysteine
NHHNPPIF_00835	264199.stu0583	9.2e-248	862.4	Bacilli	mmuP	GO:0000096,GO:0000097,GO:0000100,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0015806,GO:0016020,GO:0016053,GO:0019752,GO:0022857,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682		ko:K02205,ko:K03293,ko:K16235,ko:K16236					ko00000,ko02000	2.A.3.1,2.A.3.1.10			Bacteria	1UHNR@1239,4HUT7@91061,COG0833@1,COG0833@2	NA|NA|NA	E	amino acid
NHHNPPIF_00836	264199.stu0582	3e-110	404.4	Bacilli	engB	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363		ko:K03978					ko00000,ko03036				Bacteria	1TSPW@1239,4HBXZ@91061,COG0218@1,COG0218@2	NA|NA|NA	D	Necessary for normal cell division and for the maintenance of normal septation
NHHNPPIF_00837	322159.STER_0625	3.7e-224	783.9	Bacilli	clpX	GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369		ko:K03544	ko04112,map04112				ko00000,ko00001,ko03110				Bacteria	1TQ00@1239,4H9U4@91061,COG1219@1,COG1219@2	NA|NA|NA	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NHHNPPIF_00838	435842.HMPREF0848_00215	9.7e-22	108.6	Bacilli													Bacteria	1W5G0@1239,2DFKW@1,2ZS8U@2,4HZFD@91061	NA|NA|NA		
NHHNPPIF_00839	322159.STER_0623	1.4e-92	345.5	Bacilli	folA		1.5.1.3,1.5.1.47,2.1.1.45,3.5.4.12	ko:K00287,ko:K00560,ko:K01493,ko:K05896,ko:K17364	ko00240,ko00670,ko00790,ko01100,ko01523,map00240,map00670,map00790,map01100,map01523	M00053,M00126,M00429,M00840	R00936,R00937,R00939,R00940,R01663,R02101,R02235,R02236,R03388,R11765	RC00074,RC00109,RC00110,RC00158,RC00219,RC00332,RC01584	ko00000,ko00001,ko00002,ko01000,ko02044,ko03036				Bacteria	1VB80@1239,4HIGJ@91061,COG0262@1,COG0262@2	NA|NA|NA	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NHHNPPIF_00840	322159.STER_0622	1.9e-166	591.7	Bacilli	thyA		2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000				Bacteria	1TSIR@1239,4HI1C@91061,COG0207@1,COG0207@2	NA|NA|NA	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NHHNPPIF_00841	264199.stu0577	5e-218	763.5	Bacilli	mvaS		2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000				Bacteria	1TR4K@1239,4HA67@91061,COG3425@1,COG3425@2	NA|NA|NA	I	synthase
NHHNPPIF_00842	322159.STER_0620	2.7e-233	814.3	Bacilli	mvaA		1.1.1.34,1.1.1.88,2.3.1.9	ko:K00021,ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,ko04152,ko04976,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020,map04152,map04976	M00088,M00095,M00373,M00374,M00375	R00238,R01177,R02081,R02082	RC00004,RC00326,RC00644	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1TPNY@1239,4HBQ3@91061,COG1257@1,COG1257@2	NA|NA|NA	C	Belongs to the HMG-CoA reductase family
NHHNPPIF_00843	904306.HMPREF9192_1305	1e-25	122.1	Firmicutes				ko:K11068					ko00000,ko02042				Bacteria	1V7Z4@1239,COG0789@1,COG0789@2	NA|NA|NA	K	hmm pf08876
NHHNPPIF_00844	322159.STER_0618	1.5e-118	432.2	Bacilli	yqfA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K11068					ko00000,ko02042				Bacteria	1TTA5@1239,4HDYT@91061,COG1272@1,COG1272@2	NA|NA|NA	K	protein, Hemolysin III
NHHNPPIF_00845	904306.HMPREF9192_1302	4.6e-22	109.8	Bacilli													Bacteria	1VFZ3@1239,2DQ82@1,3357U@2,4HNXV@91061	NA|NA|NA	S	Protein of unknown function (DUF3114)
NHHNPPIF_00846	264199.stu0574	4e-164	583.9	Bacilli													Bacteria	1VFZ3@1239,2DQ82@1,3357U@2,4HNXV@91061	NA|NA|NA	S	Protein of unknown function (DUF3114)
NHHNPPIF_00847	264199.stu0573	3.6e-70	270.8	Bacilli													Bacteria	1V202@1239,4HJ0U@91061,COG0596@1,COG0596@2	NA|NA|NA	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NHHNPPIF_00848	264199.stu0573	7.1e-48	196.4	Bacilli													Bacteria	1V202@1239,4HJ0U@91061,COG0596@1,COG0596@2	NA|NA|NA	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NHHNPPIF_00849	264199.stu0572	0.0	1319.7	Bacilli	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1TP78@1239,4HABZ@91061,COG0441@1,COG0441@2	NA|NA|NA	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NHHNPPIF_00850	889204.HMPREF9423_1244	3.5e-49	200.7	Bacilli	XK27_13030												Bacteria	1VBNS@1239,2DMJF@1,32RYX@2,4HMXU@91061	NA|NA|NA		
NHHNPPIF_00851	264199.stu0570	3.4e-247	860.5	Bacilli	mgs	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576	2.4.1.337	ko:K19002	ko00561,ko01100,map00561,map01100		R10850	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003		GT4		Bacteria	1TPTA@1239,4HA41@91061,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyltransferase, group 1 family protein
NHHNPPIF_00852	322159.STER_0610	7.6e-191	672.9	Bacilli	dgs		2.4.1.208	ko:K13677	ko00561,ko01100,map00561,map01100		R05164	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003		GT4		Bacteria	1TPSS@1239,4HBKA@91061,COG0438@1,COG0438@2	NA|NA|NA	M	Glycosyltransferase, group 1 family protein
NHHNPPIF_00853	435842.HMPREF0848_00198	2.5e-08	65.5	Firmicutes													Bacteria	1UXB4@1239,COG4932@1,COG4932@2	NA|NA|NA	M	Pilin isopeptide linkage domain protein
NHHNPPIF_00854	1046629.Ssal_01596	1.8e-49	202.2	Bacteria				ko:K02460	ko03070,ko05111,map03070,map05111	M00331			ko00000,ko00001,ko00002,ko02044	3.A.15			Bacteria	COG3156@1,COG3156@2,COG4932@1,COG4932@2	NA|NA|NA	U	protein secretion
NHHNPPIF_00855	1046629.Ssal_01596	3e-29	134.4	Bacteria				ko:K02460	ko03070,ko05111,map03070,map05111	M00331			ko00000,ko00001,ko00002,ko02044	3.A.15			Bacteria	COG3156@1,COG3156@2,COG4932@1,COG4932@2	NA|NA|NA	U	protein secretion
NHHNPPIF_00857	264199.stu0566	2e-118	431.8	Bacilli	mtnN		3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000				Bacteria	1U7WK@1239,4HB8K@91061,COG0775@1,COG0775@2	NA|NA|NA	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NHHNPPIF_00858	322159.STER_0605	2.5e-21	107.8	Bacteria													Bacteria	2DC3Q@1,2ZCSA@2	NA|NA|NA		
NHHNPPIF_00859	322159.STER_0604	1e-96	359.4	Bacilli	nudF		3.6.1.13	ko:K01515	ko00230,map00230		R01054	RC00002	ko00000,ko00001,ko01000			iHN637.CLJU_RS05505,iSB619.SA_RS07540,iYO844.BSU23610	Bacteria	1V6F5@1239,4HII9@91061,COG0494@1,COG0494@2	NA|NA|NA	L	AdP-ribose pyrophosphatase
NHHNPPIF_00860	322159.STER_0603	1.8e-251	874.8	Bacilli	glmU	GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030203,GO:0030260,GO:0033692,GO:0034637,GO:0034645,GO:0035635,GO:0040007,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509	2.3.1.157,2.7.7.23	ko:K04042,ko:K11528	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP88@1239,4H9V5@91061,COG1207@1,COG1207@2	NA|NA|NA	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NHHNPPIF_00861	1046629.Ssal_01605	6.2e-185	653.3	Bacilli	fni		1.1.1.88,5.3.3.2	ko:K00054,ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123,R02081	RC00004,RC00455,RC00644	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQZ3@1239,4HAMV@91061,COG1304@1,COG1304@2	NA|NA|NA	C	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NHHNPPIF_00862	322159.STER_0600	3.1e-176	624.4	Bacilli	mvaK2		2.7.1.36,2.7.1.43,2.7.4.2	ko:K00869,ko:K00938,ko:K16190	ko00040,ko00053,ko00520,ko00900,ko01100,ko01110,ko01130,ko04146,map00040,map00053,map00520,map00900,map01100,map01110,map01130,map04146	M00014,M00095	R01476,R02245,R03245	RC00002,RC00017,RC00078	ko00000,ko00001,ko00002,ko01000				Bacteria	1VXNZ@1239,4IRFS@91061,COG1577@1,COG1577@2	NA|NA|NA	I	GHMP kinases N terminal domain
NHHNPPIF_00863	264199.stu0560	1.1e-170	605.9	Bacilli	mvaD		4.1.1.33	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095	R01121	RC00453	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQXR@1239,4HAM6@91061,COG3407@1,COG3407@2	NA|NA|NA	I	diphosphomevalonate decarboxylase
NHHNPPIF_00864	264199.stu0559	4.6e-136	490.7	Bacilli	mvk		1.1.1.88,2.3.3.10,2.7.1.36	ko:K00054,ko:K00869,ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,ko04146,map00072,map00280,map00650,map00900,map01100,map01110,map01130,map04146	M00088,M00095	R01978,R02081,R02245	RC00002,RC00004,RC00017,RC00503,RC00644	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPVW@1239,4IRCB@91061,COG1577@1,COG1577@2	NA|NA|NA	I	mevalonate kinase
NHHNPPIF_00865	264199.stu0558	8.8e-104	382.9	Bacilli	GBS0088			ko:K09962					ko00000				Bacteria	1V1YD@1239,4HGK6@91061,COG3575@1,COG3575@2	NA|NA|NA	J	protein conserved in bacteria
NHHNPPIF_00866	264199.stu0557	1.3e-246	858.6	Bacilli	merA	GO:0000302,GO:0000305,GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0019725,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901530,GO:1901700,GO:1990748	1.16.1.1	ko:K00520,ko:K21739					ko00000,ko01000				Bacteria	1TP1W@1239,4HBZF@91061,COG1249@1,COG1249@2	NA|NA|NA	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NHHNPPIF_00867	435842.HMPREF0848_00185	9.1e-48	196.1	Bacilli	ald	GO:0000286,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009653,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030154,GO:0030435,GO:0032502,GO:0043436,GO:0043934,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048646,GO:0048856,GO:0048869,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100		R00396	RC00008	ko00000,ko00001,ko01000			iAF987.Gmet_1099	Bacteria	1TNZ5@1239,4HABX@91061,COG0686@1,COG0686@2	NA|NA|NA	C	Belongs to the AlaDH PNT family
NHHNPPIF_00868	264199.stu0555	3.4e-17	93.2	Bacteria	ald	GO:0000286,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009653,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030154,GO:0030435,GO:0032502,GO:0043436,GO:0043934,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048646,GO:0048856,GO:0048869,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100		R00396	RC00008	ko00000,ko00001,ko01000			iAF987.Gmet_1099	Bacteria	COG0686@1,COG0686@2	NA|NA|NA	E	alanine dehydrogenase activity
NHHNPPIF_00869	322159.STER_0594	5.7e-219	766.5	Bacilli	hipO		3.5.1.47	ko:K01436,ko:K05823,ko:K21613	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00525	R02733	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000,ko01002				Bacteria	1TPD7@1239,4H9WQ@91061,COG1473@1,COG1473@2	NA|NA|NA	E	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NHHNPPIF_00870	322159.STER_0593	8.8e-133	479.6	Bacilli	rsuA		5.4.99.19,5.4.99.22	ko:K06178,ko:K06183					ko00000,ko01000,ko03009				Bacteria	1TQZ2@1239,4H9VU@91061,COG1187@1,COG1187@2	NA|NA|NA	J	Belongs to the pseudouridine synthase RsuA family
NHHNPPIF_00871	322159.STER_0592	5.6e-113	413.7	Bacilli													Bacteria	1V6KW@1239,4IPIC@91061,COG1814@1,COG1814@2	NA|NA|NA	S	VIT family
NHHNPPIF_00872	322159.STER_0591	5e-142	510.4	Bacilli	deoD_1		2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100		R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000				Bacteria	1V6T2@1239,4HCSE@91061,COG2820@1,COG2820@2	NA|NA|NA	F	Phosphorylase superfamily
NHHNPPIF_00873	1035184.HMPREF1042_1749	2.9e-17	95.1	Streptococcus anginosus group													Bacteria	1TVS7@1239,29ZMX@1,30MNF@2,42DTT@671232,4I418@91061	NA|NA|NA		
NHHNPPIF_00874	264199.stu0549	1.2e-26	125.2	Bacilli	XK27_00085			ko:K07729					ko00000,ko03000				Bacteria	1VERT@1239,4HNID@91061,COG1476@1,COG1476@2	NA|NA|NA	K	Transcriptional
NHHNPPIF_00875	1046629.Ssal_01622	3.4e-196	690.6	Bacilli	yceA			ko:K07146					ko00000				Bacteria	1TRG7@1239,4HA0J@91061,COG1054@1,COG1054@2	NA|NA|NA	S	Belongs to the UPF0176 family
NHHNPPIF_00876	264199.stu0547	5.4e-122	443.7	Bacilli	sagI			ko:K01992		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1USMY@1239,4HC3J@91061,COG1511@1,COG1511@2	NA|NA|NA	S	ABC-2 type transporter
NHHNPPIF_00877	322159.STER_0586	4.8e-168	597.0	Bacilli				ko:K01990,ko:K01992		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1UZK5@1239,4HB2Q@91061,COG1131@1,COG1131@2	NA|NA|NA	V	ABC transporter
NHHNPPIF_00878	264199.stu0545	1.1e-178	632.5	Bacilli			2.7.7.73,2.7.7.80	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122		R07459	RC00043	ko00000,ko00001,ko01000				Bacteria	1TQ3U@1239,4HBGP@91061,COG0476@1,COG0476@2	NA|NA|NA	H	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NHHNPPIF_00879	264199.stu0545	6.3e-27	125.9	Bacilli			2.7.7.73,2.7.7.80	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122		R07459	RC00043	ko00000,ko00001,ko01000				Bacteria	1TQ3U@1239,4HBGP@91061,COG0476@1,COG0476@2	NA|NA|NA	H	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NHHNPPIF_00880	322159.STER_0583	2.1e-131	474.9	Bacilli	rr02												Bacteria	1TXDF@1239,4HDA7@91061,COG3279@1,COG3279@2	NA|NA|NA	KT	response regulator
NHHNPPIF_00881	322159.STER_0582	1.3e-214	752.3	Bacilli			2.7.13.3	ko:K07706	ko02020,ko02024,map02020,map02024	M00495			ko00000,ko00001,ko00002,ko01000,ko01001,ko02022				Bacteria	1UDI2@1239,4HF65@91061,COG3290@1,COG3290@2	NA|NA|NA	T	signal transduction protein with a C-terminal ATPase domain
NHHNPPIF_00882	1046629.Ssal_01624	3.4e-121	441.0	Bacilli	nagB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0008150,GO:0008152,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135	3.1.1.31,3.5.99.6	ko:K01057,ko:K02564	ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R00765,R02035	RC00163,RC00537	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP10@1239,4HAG4@91061,COG0363@1,COG0363@2	NA|NA|NA	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NHHNPPIF_00883	322159.STER_0580	4.6e-199	700.3	Bacilli	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568					ko00000,ko01000,ko03016				Bacteria	1TPKD@1239,4H9PT@91061,COG0809@1,COG0809@2	NA|NA|NA	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NHHNPPIF_00884	322159.STER_0579	0.0	1138.3	Bacilli	lmrA			ko:K06147,ko:K18888	ko02010,map02010	M00706			ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21			Bacteria	1TP0B@1239,4HA3S@91061,COG1132@1,COG1132@2	NA|NA|NA	V	abc transporter atp-binding protein
NHHNPPIF_00885	322159.STER_0578	0.0	1098.6	Bacilli	mdlB			ko:K06147,ko:K06148,ko:K18887	ko02010,map02010	M00706			ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21			Bacteria	1TP0B@1239,4H9SC@91061,COG1132@1,COG1132@2	NA|NA|NA	V	abc transporter atp-binding protein
NHHNPPIF_00887	322159.STER_0576	0.0	1226.5	Firmicutes													Bacteria	1V15F@1239,COG3266@1,COG3266@2	NA|NA|NA	M	the current gene model (or a revised gene model) may contain a
NHHNPPIF_00888	904306.HMPREF9192_0446	6.5e-50	203.4	Bacilli				ko:K14194,ko:K14195	ko05150,map05150				ko00000,ko00001				Bacteria	1UYRE@1239,4ISZF@91061,COG2373@1,COG2373@2,COG4932@1,COG4932@2	NA|NA|NA	M	YSIRK type signal peptide
NHHNPPIF_00889	322159.STER_0574	3e-92	345.1	Bacteria													Bacteria	2DVN5@1,33WG3@2	NA|NA|NA	S	MucBP domain
NHHNPPIF_00891	322159.STER_1347	2.8e-164	584.7	Bacilli	hrtB			ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	1VRMK@1239,4HTA7@91061,COG0577@1,COG0577@2	NA|NA|NA	V	MacB-like periplasmic core domain
NHHNPPIF_00892	322159.STER_1348	1.3e-117	429.1	Bacilli	devA		3.6.3.25	ko:K02003,ko:K06020,ko:K09810	ko02010,map02010	M00255,M00258			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125			Bacteria	1TQP5@1239,4HBXK@91061,COG1136@1,COG1136@2	NA|NA|NA	V	abc transporter atp-binding protein
NHHNPPIF_00893	1410626.JHXB01000031_gene1709	1.6e-18	98.2	unclassified Lachnospiraceae													Bacteria	1TRUP@1239,24AJD@186801,27KEC@186928,COG2801@1,COG2801@2	NA|NA|NA	L	Integrase core domain
NHHNPPIF_00894	1116231.SMA_0720	9.1e-229	799.3	Bacilli													Bacteria	1TQ93@1239,4HJK9@91061,COG3464@1,COG3464@2	NA|NA|NA	L	Transposase
NHHNPPIF_00895	1116231.SMA_1153	8.9e-239	832.4	Bacilli													Bacteria	1VRXQ@1239,4HUID@91061,COG0582@1,COG0582@2	NA|NA|NA	L	Belongs to the 'phage' integrase family
NHHNPPIF_00896	1214166.ALLG01000022_gene225	1.2e-28	132.1	Streptococcus suis													Bacteria	1U93V@1239,1WTPP@1307,29R26@1,30C3A@2,4IJ4N@91061	NA|NA|NA	S	Domain of unknown function (DUF3173)
NHHNPPIF_00897	1116231.SMA_1373	6.1e-32	142.9	Bacilli													Bacteria	1VK84@1239,4HRBT@91061,COG1396@1,COG1396@2	NA|NA|NA	K	transcriptional
NHHNPPIF_00898	866775.HMPREF9243_1999	8.8e-72	276.9	Bacilli				ko:K20460,ko:K20461	ko02010,map02010	M00813			ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5			Bacteria	1V3PM@1239,4HHIJ@91061,COG4200@1,COG4200@2	NA|NA|NA	S	ABC-2 family transporter protein
NHHNPPIF_00899	764298.STRMA_1787	9.7e-82	310.1	Bacilli				ko:K20460,ko:K20461	ko02010,map02010	M00813			ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5			Bacteria	1V5VS@1239,4HH7H@91061,COG4200@1,COG4200@2	NA|NA|NA	S	ABC-2 family transporter protein
NHHNPPIF_00900	764298.STRMA_1786	7.2e-116	423.7	Bacilli	bcrA			ko:K20459	ko02010,map02010	M00813			ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5			Bacteria	1TP4J@1239,4HBGH@91061,COG1131@1,COG1131@2	NA|NA|NA	V	abc transporter atp-binding protein
NHHNPPIF_00901	40041.SZO_07670	6.4e-205	720.7	Streptococcus dysgalactiae group				ko:K20344	ko02010,ko02024,map02010,map02024				ko00000,ko00001,ko02000	3.A.1.112			Bacteria	1M9ZS@119603,1V77J@1239,4HAX2@91061,COG2274@1,COG2274@2	NA|NA|NA	V	Lantibiotic transport processing ATP-binding protein
NHHNPPIF_00903	764298.STRMA_1785	6.8e-93	347.1	Bacilli													Bacteria	1TYPK@1239,4HBUE@91061,COG0745@1,COG0745@2	NA|NA|NA	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHHNPPIF_00904	764298.STRMA_1784	6.5e-169	600.5	Bacilli													Bacteria	1TS12@1239,4HEKK@91061,COG0642@1,COG2205@2	NA|NA|NA	T	PhoQ Sensor
NHHNPPIF_00905	1116231.SMA_1385	2.3e-214	751.5	Bacilli													Bacteria	1V2SB@1239,4HFEX@91061,COG3843@1,COG3843@2	NA|NA|NA	U	relaxase
NHHNPPIF_00906	904306.HMPREF9192_1426	7.9e-73	279.6	Bacilli													Bacteria	1V2SB@1239,4HFEX@91061,COG3843@1,COG3843@2	NA|NA|NA	U	relaxase
NHHNPPIF_00907	246201.SM12261_0096	2.6e-56	224.6	Streptococcus mitis													Bacteria	1U4EX@1239,2DKBU@1,2TPSS@28037,3094K@2,4IE7E@91061	NA|NA|NA	S	Bacterial mobilisation protein (MobC)
NHHNPPIF_00908	904306.HMPREF9192_1424	1.1e-54	219.2	Bacilli													Bacteria	1W52Y@1239,2BWBR@1,2ZDFR@2,4I0XT@91061	NA|NA|NA		
NHHNPPIF_00909	1116231.SMA_1416	1.6e-34	151.4	Bacilli													Bacteria	1VDTP@1239,2E2ST@1,32XV1@2,4HYGP@91061	NA|NA|NA		
NHHNPPIF_00910	1123304.AQYA01000037_gene310	3e-90	337.8	Bacilli													Bacteria	1TSFX@1239,4HGAF@91061,COG2253@1,COG2253@2	NA|NA|NA	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system
NHHNPPIF_00911	1116231.SMA_1418	8.1e-108	396.4	Bacilli	abiGI												Bacteria	1V3JU@1239,4HMVW@91061,COG5340@1,COG5340@2	NA|NA|NA	K	Transcriptional regulator, AbiEi antitoxin
NHHNPPIF_00912	663952.SDD27957_04360	0.0	1274.6	Bacilli													Bacteria	1VPFZ@1239,4HFGV@91061,COG3942@1,COG3942@2	NA|NA|NA	M	CHAP domain protein
NHHNPPIF_00913	663952.SDD27957_04360	1.5e-43	182.6	Bacilli													Bacteria	1VPFZ@1239,4HFGV@91061,COG3942@1,COG3942@2	NA|NA|NA	M	CHAP domain protein
NHHNPPIF_00914	873448.STRPO_2031	0.0	1500.0	Bacilli													Bacteria	1TPDR@1239,4HUB9@91061,COG3451@1,COG3451@2	NA|NA|NA	U	'COG3451 Type IV secretory pathway, VirB4 components'
NHHNPPIF_00915	996306.SSUR61_1148	4.4e-53	213.8	Streptococcus suis	XK27_00550												Bacteria	1U92M@1239,1WTK7@1307,2AMBF@1,31C6I@2,4IJ34@91061	NA|NA|NA	S	PrgI family protein
NHHNPPIF_00916	1123304.AQYA01000037_gene305	3.3e-139	501.1	Bacilli	XK27_00555												Bacteria	1VY42@1239,2EFFF@1,33986@2,4HMPN@91061	NA|NA|NA		
NHHNPPIF_00917	1116231.SMA_1423	3.2e-34	150.6	Bacilli	XK27_00560												Bacteria	1W4XR@1239,295KB@1,2ZSXU@2,4I17I@91061	NA|NA|NA		
NHHNPPIF_00918	1116231.SMA_1424	0.0	1212.2	Bacilli	traG			ko:K03205	ko03070,map03070	M00333			ko00000,ko00001,ko00002,ko02044	3.A.7			Bacteria	1UAJF@1239,4IPX4@91061,COG3505@1,COG3505@2	NA|NA|NA	U	COG3505 Type IV secretory pathway, VirD4 components
NHHNPPIF_00919	663952.SDD27957_08365	1.1e-78	299.3	Streptococcus dysgalactiae group													Bacteria	1MA0F@119603,1U9FT@1239,29R8I@1,30C9Y@2,4IJJE@91061	NA|NA|NA		
NHHNPPIF_00920	1123304.AQYA01000037_gene301	3.9e-91	340.9	Bacteria			3.4.11.19	ko:K01266,ko:K07052					ko00000,ko01000,ko01002				Bacteria	COG1266@1,COG1266@2	NA|NA|NA	V	CAAX protease self-immunity
NHHNPPIF_00921	663952.SDD27957_04310	3.8e-37	160.2	Streptococcus dysgalactiae group													Bacteria	1MA3U@119603,1TXEG@1239,2DJ81@1,304Y6@2,4I6CS@91061	NA|NA|NA		
NHHNPPIF_00922	1403946.Q615_SPAC00123G0036	1.9e-49	201.8	Streptococcus anginosus group													Bacteria	1TW0J@1239,2DIU1@1,3044F@2,42EHG@671232,4I4P9@91061	NA|NA|NA		
NHHNPPIF_00923	883168.HMPREF9318_00463	1.6e-73	282.0	Firmicutes	XK27_00590												Bacteria	1W4PT@1239,2EV5A@1,33NK4@2	NA|NA|NA		
NHHNPPIF_00924	1123304.AQYA01000037_gene298	7.9e-260	902.5	Bacilli	hpaIIM		2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036				Bacteria	1TPNE@1239,4HB9C@91061,COG0270@1,COG0270@2	NA|NA|NA	H	cytosine-specific methyltransferase
NHHNPPIF_00925	663952.SDD27957_04290	4.8e-10	68.9	Streptococcus dysgalactiae group													Bacteria	1MA66@119603,1TXFK@1239,2DJ8F@1,304Z3@2,4I6DZ@91061	NA|NA|NA		
NHHNPPIF_00926	759913.SDSE_1324	4.5e-133	480.7	Streptococcus dysgalactiae group	repA												Bacteria	1M9YD@119603,1VHQA@1239,2DP1C@1,3304N@2,4HPY6@91061	NA|NA|NA	S	Replication initiator protein A (RepA) N-terminus
NHHNPPIF_00927	759913.SDSE_1325	2.1e-19	100.9	Streptococcus dysgalactiae group													Bacteria	1MA5I@119603,1TXF4@1239,2BMA2@1,32FTX@2,4I6DG@91061	NA|NA|NA		
NHHNPPIF_00928	322159.STER_0568	3e-52	211.1	Bacilli	rplL			ko:K02935	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V6EI@1239,4HIGQ@91061,COG0222@1,COG0222@2	NA|NA|NA	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NHHNPPIF_00929	435842.HMPREF0848_00164	8.2e-77	293.1	Bacilli	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113		ko:K02864,ko:K02935	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V3JJ@1239,4HH0N@91061,COG0244@1,COG0244@2	NA|NA|NA	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NHHNPPIF_00930	264199.stu0535	8.2e-28	129.0	Bacteria	ytrF			ko:K02004,ko:K16918	ko02010,map02010	M00258,M00584			ko00000,ko00001,ko00002,ko02000	3.A.1			Bacteria	COG0577@1,COG0577@2	NA|NA|NA	V	efflux transmembrane transporter activity
NHHNPPIF_00931	264199.stu0533	3.1e-31	141.0	Bacteria				ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	COG0577@1,COG0577@2	NA|NA|NA	V	efflux transmembrane transporter activity
NHHNPPIF_00932	264199.stu0532	3.6e-35	153.7	Bacteria													Bacteria	COG0577@1,COG0577@2	NA|NA|NA	V	efflux transmembrane transporter activity
NHHNPPIF_00933	322159.STER_0561	2.1e-129	468.4	Bacilli			2.1.1.223	ko:K15460					ko00000,ko01000,ko03016				Bacteria	1UJ4P@1239,4IT17@91061,COG4123@1,COG4123@2	NA|NA|NA	S	Putative SAM-dependent methyltransferase
NHHNPPIF_00934	264199.stu0527	0.0	2065.0	Bacilli	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPID@1239,4HAEY@91061,COG0458@1,COG0458@2	NA|NA|NA	F	carbamoyl-phosphate synthetase ammonia chain
NHHNPPIF_00935	322159.STER_0558	2.1e-210	738.0	Bacilli	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01955,ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000			iNJ661.Rv1383,iYO844.BSU15510	Bacteria	1TQ8N@1239,4H9Z0@91061,COG0505@1,COG0505@2	NA|NA|NA	F	carbamoyl-phosphate synthetase glutamine chain
NHHNPPIF_00936	264199.stu0525	1e-173	615.9	Bacilli	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00608,ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000			iYO844.BSU15490	Bacteria	1TQ96@1239,4H9M6@91061,COG0540@1,COG0540@2	NA|NA|NA	F	Belongs to the ATCase OTCase family
NHHNPPIF_00937	322159.STER_0556	4.9e-227	793.5	Bacilli	pyrP			ko:K02824					ko00000,ko02000	2.A.40.1.1,2.A.40.1.2		iLJ478.TM0819	Bacteria	1TQKX@1239,4HAEU@91061,COG2233@1,COG2233@2	NA|NA|NA	F	uracil Permease
NHHNPPIF_00938	264199.stu0523	1.1e-87	329.3	Bacilli	pyrR		2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100		R00966	RC00063	ko00000,ko00001,ko01000,ko03000				Bacteria	1V3GV@1239,4HGYE@91061,COG2065@1,COG2065@2	NA|NA|NA	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NHHNPPIF_00939	264199.stu0522	5.5e-161	573.5	Bacilli	rluD	GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180					ko00000,ko01000,ko03009			iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432	Bacteria	1TPCM@1239,4HBG2@91061,COG0564@1,COG0564@2	NA|NA|NA	J	Responsible for synthesis of pseudouridine from uracil
NHHNPPIF_00940	264199.stu0521	2.6e-77	294.7	Bacilli	lspA		3.4.23.36	ko:K03101	ko03060,map03060				ko00000,ko00001,ko01000,ko01002				Bacteria	1VA9R@1239,4HIR4@91061,COG0597@1,COG0597@2	NA|NA|NA	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NHHNPPIF_00941	904306.HMPREF9192_0429	1.5e-166	592.0	Bacilli	fhuR												Bacteria	1V53I@1239,4HIEU@91061,COG0583@1,COG0583@2	NA|NA|NA	K	transcriptional regulator (lysR family)
NHHNPPIF_00946	322159.STER_0545	4.1e-141	507.3	Bacteria	ppiA		5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217				ko00000,ko00001,ko01000,ko03110,ko04147				Bacteria	COG0652@1,COG0652@2	NA|NA|NA	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NHHNPPIF_00947	904306.HMPREF9192_0423	1.3e-181	642.5	Bacilli	pts33BCA			ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	M00271			ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6			Bacteria	1TP5X@1239,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2	NA|NA|NA	G	pts system
NHHNPPIF_00948	1046629.Ssal_01653	7.4e-25	119.0	Bacilli	pts33BCA		2.7.1.201,2.7.1.208,2.7.1.211	ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02808,ko:K02809,ko:K02810,ko:K02817,ko:K02818,ko:K02819,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	M00265,M00266,M00268,M00269,M00270,M00271,M00272,M00303,M00806	R00811,R02738,R02780,R04111,R04394,R05132,R08559	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1,4.A.1.1.11,4.A.1.1.12,4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.13,4.A.1.2.2,4.A.1.2.4,4.A.1.2.5,4.A.1.2.6,4.A.1.2.8,4.A.1.2.9			Bacteria	1TP5X@1239,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2	NA|NA|NA	G	pts system
NHHNPPIF_00949	1215915.BN193_08720	3.2e-09	68.9	Lactococcus	uvrX		2.7.7.7	ko:K02346,ko:K03502,ko:K14161					ko00000,ko01000,ko03400				Bacteria	1TP42@1239,1YBFV@1357,4HA1P@91061,COG0389@1,COG0389@2	NA|NA|NA	L	impB/mucB/samB family
NHHNPPIF_00950	264199.stu0509	2e-250	871.3	Bacilli	cycA	GO:0001761,GO:0001762,GO:0003333,GO:0003674,GO:0005215,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015180,GO:0015187,GO:0015238,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015808,GO:0015816,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0022858,GO:0022889,GO:0032328,GO:0032329,GO:0034220,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0042940,GO:0042941,GO:0042942,GO:0042943,GO:0042944,GO:0042945,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039		ko:K03293,ko:K11737					ko00000,ko02000	2.A.3.1,2.A.3.1.7		iECO111_1330.ECO111_5093,iECO26_1355.ECO26_5376,iEcHS_1320.EcHS_A4458,iSbBS512_1146.SbBS512_E4749,iYL1228.KPN_04601	Bacteria	1TP97@1239,4H9QX@91061,COG1113@1,COG1113@2	NA|NA|NA	E	permease
NHHNPPIF_00951	322159.STER_0891	1.4e-151	542.3	Bacilli	glcU			ko:K05340					ko00000,ko02000	2.A.7.5			Bacteria	1TQBN@1239,4HAVH@91061,COG4975@1,COG4975@2	NA|NA|NA	U	Glucose uptake
NHHNPPIF_00952	264199.stu0852	2.3e-93	348.2	Bacilli	hsdM		2.1.1.72	ko:K03427					ko00000,ko01000,ko02048				Bacteria	1TPGZ@1239,4HA1J@91061,COG0286@1,COG0286@2	NA|NA|NA	V	type I restriction-modification system
NHHNPPIF_00953	264199.stu0851	2.6e-55	221.1	Bacteria	hsdS		2.1.1.72,3.1.21.3	ko:K01154,ko:K07317					ko00000,ko01000,ko02048				Bacteria	COG0732@1,COG0732@2	NA|NA|NA	V	type I restriction modification DNA specificity domain
NHHNPPIF_00954	585203.SMSK564_1364	8.9e-11	72.4	Streptococcus mitis													Bacteria	1U4XP@1239,2DKGP@1,2TQDW@28037,309EM@2,4IEP2@91061	NA|NA|NA		
NHHNPPIF_00955	435842.HMPREF0848_00317	7.8e-59	233.0	Bacilli				ko:K13281					ko00000,ko01000				Bacteria	1VGGK@1239,4HP7S@91061,COG3272@1,COG3272@2	NA|NA|NA	S	Protein of unknown function (DUF1722)
NHHNPPIF_00956	1046629.Ssal_01457	3.3e-64	250.8	Bacilli	yqeB												Bacteria	1V717@1239,2AK1X@1,31ARI@2,4HIQ9@91061	NA|NA|NA	S	Pyrimidine dimer DNA glycosylase
NHHNPPIF_00958	1046629.Ssal_01455	2.4e-33	147.5	Firmicutes													Bacteria	1VZAT@1239,2FBVV@1,3440F@2	NA|NA|NA		
NHHNPPIF_00959	1046629.Ssal_01454	1.7e-26	124.8	Bacilli													Bacteria	1VBYM@1239,4HM2K@91061,COG1266@1,COG1266@2	NA|NA|NA	S	CAAX protease self-immunity
NHHNPPIF_00960	1046629.Ssal_01454	1e-30	139.0	Bacilli													Bacteria	1VBYM@1239,4HM2K@91061,COG1266@1,COG1266@2	NA|NA|NA	S	CAAX protease self-immunity
NHHNPPIF_00961	1046629.Ssal_01453	1.9e-27	127.9	Bacilli	estA												Bacteria	1V1CQ@1239,4HGVZ@91061,COG2755@1,COG2755@2	NA|NA|NA	E	GDSL-like Lipase/Acylhydrolase
NHHNPPIF_00962	1046629.Ssal_01451	6.2e-95	353.6	Firmicutes													Bacteria	1VYAW@1239,2F636@1,33YMH@2	NA|NA|NA		
NHHNPPIF_00963	322159.STER_0709	0.0	2040.8	Bacilli	cas9			ko:K09952					ko00000,ko01000,ko02048				Bacteria	1TPSD@1239,4HE0R@91061,COG3513@1,COG3513@2	NA|NA|NA	L	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NHHNPPIF_00964	264199.stu0658	3.2e-172	610.9	Bacilli	cas1			ko:K15342					ko00000,ko02048,ko03400				Bacteria	1TT0J@1239,4HC5E@91061,COG1518@1,COG1518@2	NA|NA|NA	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NHHNPPIF_00965	322159.STER_0711	1.8e-53	214.9	Bacteria	cas2			ko:K09951					ko00000,ko02048				Bacteria	COG3512@1,COG3512@2	NA|NA|NA	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NHHNPPIF_00966	322159.STER_0712	6.7e-198	696.4	Firmicutes													Bacteria	1W43F@1239,2DZ2B@1,34C6V@2	NA|NA|NA	S	CRISPR-associated protein Csn2 subfamily St
NHHNPPIF_00967	322159.STER_0713	9.3e-147	526.2	Bacilli	ycgQ			ko:K08986					ko00000				Bacteria	1V3EX@1239,4HGMG@91061,COG3689@1,COG3689@2	NA|NA|NA	S	TIGR03943 family
NHHNPPIF_00968	322159.STER_0714	1.4e-156	558.9	Bacilli	XK27_03015			ko:K07089					ko00000				Bacteria	1TQHK@1239,4HB25@91061,COG0701@1,COG0701@2	NA|NA|NA	S	permease
NHHNPPIF_00970	322159.STER_0716	0.0	1329.7	Bacilli	yhgF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896		ko:K06959					ko00000				Bacteria	1TPFE@1239,4HAGY@91061,COG2183@1,COG2183@2	NA|NA|NA	K	Transcriptional accessory protein
NHHNPPIF_00971	264199.stu0665	1.9e-40	171.4	Bacilli	pspC			ko:K03973					ko00000,ko02048,ko03000				Bacteria	1VF0M@1239,4IRAN@91061,COG1983@1,COG1983@2	NA|NA|NA	KT	PspC domain
NHHNPPIF_00972	322159.STER_0719	4.9e-168	597.0	Bacilli	hprK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464		ko:K06023					ko00000,ko01000				Bacteria	1TP5Z@1239,4HAXR@91061,COG1493@1,COG1493@2	NA|NA|NA	F	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NHHNPPIF_00973	264199.stu0667	1.5e-146	525.4	Bacilli	lgt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009898,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576	2.1.1.199	ko:K03438,ko:K13292					ko00000,ko01000,ko03009				Bacteria	1TPAK@1239,4HAT0@91061,COG0682@1,COG0682@2	NA|NA|NA	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NHHNPPIF_00975	322159.STER_0722	1.2e-68	265.8	Bacilli	ytxH												Bacteria	1VFY7@1239,4HNWV@91061,COG4980@1,COG4980@2	NA|NA|NA	S	General stress protein
NHHNPPIF_00977	264199.stu0671	1.7e-176	625.2	Bacilli	yegQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464		ko:K08303	ko05120,map05120				ko00000,ko00001,ko01000,ko01002				Bacteria	1TQIZ@1239,4HA2T@91061,COG0826@1,COG0826@2	NA|NA|NA	O	Peptidase U32
NHHNPPIF_00978	322159.STER_0725	3.4e-252	877.1	Bacilli	yegQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464		ko:K08303	ko05120,map05120				ko00000,ko00001,ko01000,ko01002				Bacteria	1TPRE@1239,4HBEG@91061,COG0826@1,COG0826@2	NA|NA|NA	O	Peptidase U32
NHHNPPIF_00979	322159.STER_0726	2.7e-86	324.7	Bacilli	bioY			ko:K03523	ko02010,map02010	M00581,M00582			ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2			Bacteria	1VA1G@1239,4HNE8@91061,COG1268@1,COG1268@2	NA|NA|NA	S	biotin synthase
NHHNPPIF_00981	264199.stu0676	1.1e-33	148.7	Bacilli	XK27_12190												Bacteria	1VEFE@1239,4HNSP@91061,COG4443@1,COG4443@2	NA|NA|NA	S	protein conserved in bacteria
NHHNPPIF_00982	322159.STER_0729	3e-235	820.8	Bacilli	mntH	GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281		ko:K03322					ko00000,ko02000	2.A.55.2.6,2.A.55.3			Bacteria	1TPT1@1239,4HAEA@91061,COG1914@1,COG1914@2	NA|NA|NA	P	H( )-stimulated, divalent metal cation uptake system
NHHNPPIF_00984	1095726.HMPREF1116_0267	1.5e-101	375.6	Bacteria	yiiE												Bacteria	COG3548@1,COG3548@2	NA|NA|NA	S	protein homotetramerization
NHHNPPIF_00991	264199.stu0508	4.5e-39	166.8	Bacilli	ynzC												Bacteria	1VEKJ@1239,4HNIB@91061,COG4224@1,COG4224@2	NA|NA|NA	S	UPF0291 protein
NHHNPPIF_00992	322159.STER_0540	0.0	1283.5	Bacilli	glyS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01879,ko:K14164	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iAPECO1_1312.APECO1_2891,iE2348C_1286.E2348C_3810,iECABU_c1320.ECABU_c40010,iECED1_1282.ECED1_4242,iECH74115_1262.ECH74115_4934,iECNA114_1301.ECNA114_3710,iECOK1_1307.ECOK1_4005,iECP_1309.ECP_3661,iECS88_1305.ECS88_3976,iECSF_1327.ECSF_3393,iECSP_1301.ECSP_4554,iECs_1301.ECs4442,iG2583_1286.G2583_4300,iJN678.glyS,iUMN146_1321.UM146_17960,iUTI89_1310.UTI89_C4099,ic_1306.c4378	Bacteria	1TNZ7@1239,4H9NT@91061,COG0751@1,COG0751@2	NA|NA|NA	J	Glycyl-tRNA synthetase beta subunit
NHHNPPIF_00993	264199.stu0505	4.8e-176	623.6	Bacilli	glyQ	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016875,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01878,ko:K14164	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iAF1260.b3560,iAF987.Gmet_2942,iJO1366.b3560,iPC815.YPO4072,iY75_1357.Y75_RS19360	Bacteria	1TPW8@1239,4HBCF@91061,COG0752@1,COG0752@2	NA|NA|NA	J	glycyl-tRNA synthetase alpha subunit
NHHNPPIF_00994	904306.HMPREF9192_0417	6.1e-63	246.9	Bacilli													Bacteria	1U601@1239,4HBYW@91061,COG3949@1,COG3949@2	NA|NA|NA	S	membrane
NHHNPPIF_00995	264199.stu0504	3.9e-60	237.3	Bacteria													Bacteria	COG3949@1,COG3949@2	NA|NA|NA		
NHHNPPIF_00996	264199.stu0503	2.2e-25	120.9	Bacteria													Bacteria	COG3949@1,COG3949@2	NA|NA|NA		
NHHNPPIF_00997	264199.stu0502	4.9e-51	206.8	Bacteria													Bacteria	COG3949@1,COG3949@2	NA|NA|NA		
NHHNPPIF_00998	322159.STER_0537	8e-221	772.7	Bacilli	nagA		3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130		R02059	RC00166,RC00300	ko00000,ko00001,ko01000				Bacteria	1TPFK@1239,4HC6C@91061,COG1820@1,COG1820@2	NA|NA|NA	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NHHNPPIF_00999	1046629.Ssal_01661	1.2e-92	345.9	Bacilli	nptA			ko:K03324					ko00000,ko02000	2.A.58.2			Bacteria	1TP4K@1239,4HAZ0@91061,COG1283@1,COG1283@2	NA|NA|NA	P	COG1283 Na phosphate symporter
NHHNPPIF_01000	322159.STER_0534	5.8e-149	533.5	Bacilli	XK27_04800												Bacteria	1VAFW@1239,4HIFQ@91061,COG0561@1,COG0561@2	NA|NA|NA	S	Sucrose-6F-phosphate phosphohydrolase
NHHNPPIF_01001	264199.stu0496	1.3e-103	382.5	Firmicutes	mur1			ko:K02395					ko00000,ko02035				Bacteria	1UYRM@1239,COG1705@1,COG1705@2	NA|NA|NA	NU	mannosyl-glycoprotein
NHHNPPIF_01002	322159.STER_0532	1.2e-52	212.2	Firmicutes	glnB			ko:K04751,ko:K04752	ko02020,map02020				ko00000,ko00001				Bacteria	1V9Z5@1239,COG0347@1,COG0347@2	NA|NA|NA	K	Belongs to the P(II) protein family
NHHNPPIF_01003	322159.STER_0531	3.7e-232	810.4	Bacilli	amt			ko:K03320					ko00000,ko02000	1.A.11			Bacteria	1TQYG@1239,4HBGK@91061,COG0004@1,COG0004@2	NA|NA|NA	P	Ammonium Transporter
NHHNPPIF_01006	1198676.SMUGS5_00840	5.3e-11	72.0	Firmicutes													Bacteria	1VP0T@1239,2EG8N@1,33A0G@2	NA|NA|NA		
NHHNPPIF_01019	1123299.AUKZ01000036_gene1534	1e-13	81.6	Bacteria	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02914	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	COG0230@1,COG0230@2	NA|NA|NA	J	Ribosomal protein L34
NHHNPPIF_01021	264199.stu1809	3.2e-184	651.0	Bacilli	jag			ko:K06346					ko00000				Bacteria	1V3IN@1239,4HHHU@91061,COG1847@1,COG1847@2	NA|NA|NA	S	RNA-binding protein
NHHNPPIF_01022	264199.stu1810	8.5e-141	506.5	Bacilli	yidC			ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9			Bacteria	1TQ0J@1239,4HB3J@91061,COG0706@1,COG0706@2	NA|NA|NA	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NHHNPPIF_01023	264199.stu1811	1.3e-54	218.8	Bacilli	rnpA	GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904	3.1.26.5	ko:K03536,ko:K08998					ko00000,ko01000,ko03016				Bacteria	1VA78@1239,4HKG6@91061,COG0594@1,COG0594@2	NA|NA|NA	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NHHNPPIF_01024	264199.stu1812	1.2e-263	915.2	Bacilli	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1TNZ6@1239,4HB24@91061,COG0165@1,COG0165@2	NA|NA|NA	E	Argininosuccinate lyase
NHHNPPIF_01025	264199.stu1813	2.9e-229	800.8	Bacilli	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147			iJN678.argG,iSB619.SA_RS04675	Bacteria	1TP3X@1239,4HA1E@91061,COG0137@1,COG0137@2	NA|NA|NA	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily
NHHNPPIF_01026	264199.stu1814	1.5e-280	971.5	Bacilli	gltX	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009986,GO:0030246,GO:0030247,GO:0044424,GO:0044464,GO:2001065	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016			iSB619.SA_RS02860	Bacteria	1TPJC@1239,4HAKH@91061,COG0008@1,COG0008@2	NA|NA|NA	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NHHNPPIF_01027	264199.stu1815	1.6e-62	245.4	Bacteria	amiA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	COG4166@1,COG4166@2	NA|NA|NA	E	transmembrane transport
NHHNPPIF_01028	904306.HMPREF9192_2056	1.5e-181	642.1	Bacilli	amiA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1TQVS@1239,4HCCB@91061,COG4166@1,COG4166@2	NA|NA|NA	E	ABC transporter, substrate-binding protein, family 5
NHHNPPIF_01029	264199.stu1817	1.8e-119	435.3	Bacilli	rplA	GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113		ko:K02863	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1TPTS@1239,4HAK4@91061,COG0081@1,COG0081@2	NA|NA|NA	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NHHNPPIF_01030	264199.stu1818	3.7e-70	270.8	Bacilli	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02867	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V1BS@1239,4HFQ0@91061,COG0080@1,COG0080@2	NA|NA|NA	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NHHNPPIF_01031	264199.stu1819	3.5e-50	204.1	Firmicutes													Bacteria	1VNK9@1239,2DSU9@1,33HF9@2	NA|NA|NA	S	Protein of unknown function (DUF3397)
NHHNPPIF_01032	264199.stu1820	2e-88	331.6	Bacilli	cah		4.2.1.1	ko:K01673	ko00910,map00910		R00132,R10092	RC02807	ko00000,ko00001,ko01000				Bacteria	1V0TA@1239,4HB9V@91061,COG0288@1,COG0288@2	NA|NA|NA	P	Reversible hydration of carbon dioxide
NHHNPPIF_01033	904306.HMPREF9192_2050	9.1e-29	132.5	Bacilli	WQ51_05710												Bacteria	1V6BD@1239,4HIAR@91061,COG2013@1,COG2013@2	NA|NA|NA	S	Mitochondrial biogenesis AIM24
NHHNPPIF_01034	264199.stu1822	3e-34	150.6	Bacteria	WQ51_05710												Bacteria	COG2013@1,COG2013@2	NA|NA|NA	S	Mitochondrial biogenesis AIM24
NHHNPPIF_01035	435842.HMPREF0848_01845	1.4e-11	74.3	Bacilli	WQ51_05710												Bacteria	1V6BD@1239,4HIAR@91061,COG2013@1,COG2013@2	NA|NA|NA	S	Mitochondrial biogenesis AIM24
NHHNPPIF_01036	264199.stu1823	1.4e-226	792.0	Bacilli	radA			ko:K04485					ko00000,ko03400				Bacteria	1TQ7Y@1239,4H9YC@91061,COG1066@1,COG1066@2	NA|NA|NA	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NHHNPPIF_01037	264199.stu1824	1.1e-80	305.8	Bacilli	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23,4.1.1.36,6.3.2.5	ko:K01520,ko:K13038	ko00240,ko00770,ko00983,ko01100,map00240,map00770,map00983,map01100	M00053,M00120	R02100,R03269,R04231,R11896	RC00002,RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000,ko03400				Bacteria	1V6HX@1239,4HIZ3@91061,COG0756@1,COG0756@2	NA|NA|NA	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NHHNPPIF_01038	264199.stu1825	1.8e-19	100.9	Bacteria	XK27_09620												Bacteria	COG0431@1,COG0431@2	NA|NA|NA	S	FMN reductase (NADPH) activity
NHHNPPIF_01039	1046629.Ssal_00181	4.6e-35	153.3	Bacteria	XK27_09620												Bacteria	COG0431@1,COG0431@2	NA|NA|NA	S	FMN reductase (NADPH) activity
NHHNPPIF_01040	904306.HMPREF9192_2046	7.4e-220	769.6	Bacilli	XK27_09615												Bacteria	1TPRA@1239,4HDA5@91061,COG0431@1,COG0431@2,COG2461@1,COG2461@2	NA|NA|NA	C	reductase
NHHNPPIF_01041	435842.HMPREF0848_01839	2.1e-91	341.7	Bacilli	fnt			ko:K06212,ko:K21993					ko00000,ko02000	1.A.16.1.1,1.A.16.1.3,1.A.16.2			Bacteria	1V164@1239,4HFJC@91061,COG2116@1,COG2116@2	NA|NA|NA	P	Formate nitrite transporter
NHHNPPIF_01042	1046629.Ssal_00177	3.5e-32	144.1	Bacteria	XK27_08585			ko:K16926		M00582			ko00000,ko00002,ko02000	3.A.1.31			Bacteria	2BY0N@1,321KG@2	NA|NA|NA	S	Psort location CytoplasmicMembrane, score
NHHNPPIF_01043	435842.HMPREF0848_01838	4.7e-29	133.3	Bacteria	XK27_08585			ko:K16926		M00582			ko00000,ko00002,ko02000	3.A.1.31			Bacteria	2BY0N@1,321KG@2	NA|NA|NA	S	Psort location CytoplasmicMembrane, score
NHHNPPIF_01044	264199.stu1832	4.4e-186	657.1	Bacilli	gpsA	GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110		R00842,R00844	RC00029	ko00000,ko00001,ko01000				Bacteria	1TQ5P@1239,4HAXW@91061,COG0240@1,COG0240@2	NA|NA|NA	I	Glycerol-3-phosphate dehydrogenase
NHHNPPIF_01045	264199.stu1833	4.8e-168	597.0	Bacilli	galU		2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQ24@1239,4HATY@91061,COG1210@1,COG1210@2	NA|NA|NA	M	UTP-glucose-1-phosphate uridylyltransferase
NHHNPPIF_01046	264199.stu1836	2.6e-118	431.4	Bacilli	gluP		3.4.21.105	ko:K19225					ko00000,ko01000,ko01002				Bacteria	1TQXT@1239,4HCDF@91061,COG0705@1,COG0705@2	NA|NA|NA	O	membrane protein (homolog of Drosophila rhomboid)
NHHNPPIF_01047	264199.stu1837	1e-93	349.4	Bacilli	ygfA	GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100		R02301	RC00183	ko00000,ko00001,ko01000			iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298	Bacteria	1VA91@1239,4HM35@91061,COG0212@1,COG0212@2	NA|NA|NA	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NHHNPPIF_01048	264199.stu1838	1e-220	772.3	Bacilli	hipO	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.1.47	ko:K01436,ko:K05823,ko:K21613	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00525	R02733	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000,ko01002				Bacteria	1TPD7@1239,4H9SG@91061,COG1473@1,COG1473@2	NA|NA|NA	E	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NHHNPPIF_01049	264199.stu1839	8.1e-59	233.8	Bacilli	dapD	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.117,2.3.1.89	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	M00016,M00525	R04364,R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000			iSbBS512_1146.SbBS512_E0158,iYO844.BSU14180	Bacteria	1TQUJ@1239,4H9KY@91061,COG2171@1,COG2171@2	NA|NA|NA	E	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NHHNPPIF_01050	264199.stu1840	7.8e-48	196.1	Bacteria				ko:K07025					ko00000				Bacteria	COG0546@1,COG0546@2	NA|NA|NA	S	glycolate biosynthetic process
NHHNPPIF_01051	264199.stu1841	1.7e-63	248.4	Bacteria				ko:K07025					ko00000				Bacteria	COG1011@1,COG1011@2	NA|NA|NA	S	phosphatase activity
NHHNPPIF_01052	322159.STER_1816	6.3e-159	566.6	Bacteria	rrmA		2.1.1.187	ko:K00563,ko:K10947			R07233	RC00003	ko00000,ko01000,ko03000,ko03009				Bacteria	COG0500@1,COG2226@2	NA|NA|NA	Q	methyltransferase
NHHNPPIF_01055	322159.STER_1819	1.2e-91	342.4	Bacilli	tadA		3.5.4.1,3.5.4.33	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100		R00974,R01411,R02922,R10223	RC00074,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016				Bacteria	1V3HZ@1239,4HH7S@91061,COG0590@1,COG0590@2	NA|NA|NA	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NHHNPPIF_01056	322159.STER_1821	5.1e-66	256.9	Bacilli	ssb_2			ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440				ko00000,ko00001,ko03029,ko03032,ko03400				Bacteria	1VXMZ@1239,4HXCW@91061,COG0629@1,COG0629@2	NA|NA|NA	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NHHNPPIF_01057	264199.stu1846	6.4e-37	159.5	Bacteria	yeeD	GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008		ko:K07112					ko00000				Bacteria	COG0425@1,COG0425@2	NA|NA|NA	O	sulfur carrier activity
NHHNPPIF_01058	264199.stu1847	2.8e-188	664.5	Bacilli	yeeE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K07112					ko00000				Bacteria	1TSNG@1239,4HDN0@91061,COG2391@1,COG2391@2	NA|NA|NA	S	Sulphur transport
NHHNPPIF_01059	264199.stu1848	7.9e-114	416.4	Bacilli	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890,ko:K06878	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1V7QA@1239,4HJBD@91061,COG0073@1,COG0073@2	NA|NA|NA	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NHHNPPIF_01060	264199.stu1849	4.2e-55	220.3	Bacilli	ytpP	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	2.7.1.180,5.3.4.1	ko:K01829,ko:K03671,ko:K03734,ko:K06196	ko04621,ko05418,map04621,map05418				ko00000,ko00001,ko01000,ko02000,ko03110	5.A.1.2			Bacteria	1VAS6@1239,4HKGM@91061,COG0526@1,COG0526@2	NA|NA|NA	CO	Thioredoxin
NHHNPPIF_01061	1035184.HMPREF1042_1989	1.8e-09	68.6	Streptococcus anginosus group													Bacteria	1TVXJ@1239,2BV7J@1,32QM1@2,42EDG@671232,4I4JA@91061	NA|NA|NA	S	Domain of unknown function (DUF4651)
NHHNPPIF_01062	322159.STER_1827	7.5e-205	719.5	Bacilli	pepA		3.4.11.7	ko:K01261,ko:K01269					ko00000,ko01000,ko01002				Bacteria	1TNZT@1239,4H9SM@91061,COG1363@1,COG1363@2	NA|NA|NA	G	COG1363 Cellulase M and related proteins
NHHNPPIF_01063	264199.stu1852	3.9e-131	474.2	Bacilli	proC		1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP1E@1239,4HCBY@91061,COG0345@1,COG0345@2	NA|NA|NA	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NHHNPPIF_01064	264199.stu1853	2.1e-109	401.7	Bacilli				ko:K07052					ko00000				Bacteria	1VEE2@1239,4HP4A@91061,COG1266@1,COG1266@2	NA|NA|NA	S	CAAX amino terminal protease family protein
NHHNPPIF_01066	264199.stu1855	1.4e-66	258.8	Bacteria				ko:K07052					ko00000				Bacteria	COG1266@1,COG1266@2	NA|NA|NA	V	CAAX protease self-immunity
NHHNPPIF_01067	1046629.Ssal_00151	2.6e-26	124.0	Bacteria	lanR			ko:K07729					ko00000,ko03000				Bacteria	COG1476@1,COG1476@2	NA|NA|NA	K	sequence-specific DNA binding
NHHNPPIF_01068	264199.stu1857	3.2e-220	770.8	Bacilli	ackA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000			iNJ661.Rv0409	Bacteria	1TQ22@1239,4HA7K@91061,COG0282@1,COG0282@2	NA|NA|NA	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NHHNPPIF_01069	264199.stu1858	4.2e-175	620.5	Bacilli	ytxK		2.1.1.72	ko:K00571					ko00000,ko01000,ko02048				Bacteria	1TRIQ@1239,4H9SE@91061,COG0827@1,COG0827@2	NA|NA|NA	L	DNA methylase
NHHNPPIF_01070	1198676.SMUGS5_08910	2.2e-11	75.1	Bacilli	comGF			ko:K02246,ko:K02248		M00429			ko00000,ko00002,ko02044				Bacteria	1VJKM@1239,4HQDT@91061,COG4940@1,COG4940@2	NA|NA|NA	U	Putative Competence protein ComGF
NHHNPPIF_01071	322159.STER_1837	1.3e-70	272.3	Bacilli	comGF			ko:K02246,ko:K02248		M00429			ko00000,ko00002,ko02044				Bacteria	1VKRP@1239,4HR6S@91061,COG4940@1,COG4940@2	NA|NA|NA	U	Competence protein ComGF
NHHNPPIF_01072	873449.STRCR_0577	4.1e-15	87.0	Firmicutes													Bacteria	1W385@1239,2ZS6J@2,COG2165@1	NA|NA|NA	NU	Type II secretory pathway pseudopilin
NHHNPPIF_01073	264199.stu1862	2.6e-56	224.6	Bacilli	cglD			ko:K02246		M00429			ko00000,ko00002,ko02044				Bacteria	1VPGT@1239,33A38@2,4HRZ0@91061,COG2165@1	NA|NA|NA	NU	Competence protein
NHHNPPIF_01074	322159.STER_1840	2.5e-42	177.9	Bacilli	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944		ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429			ko00000,ko00001,ko00002,ko02044	3.A.15			Bacteria	1VFI9@1239,4HNNT@91061,COG4537@1,COG4537@2	NA|NA|NA	U	Required for transformation and DNA binding
NHHNPPIF_01075	264199.stu1864	4.5e-152	543.9	Bacilli	cglB			ko:K02244		M00429			ko00000,ko00002,ko02044	3.A.14.1			Bacteria	1U00C@1239,4HGUA@91061,COG1459@1,COG1459@2	NA|NA|NA	NU	type II secretion system
NHHNPPIF_01076	322159.STER_1842	2.2e-176	624.8	Bacilli	comGA			ko:K02243		M00429			ko00000,ko00002,ko02044	3.A.14.1			Bacteria	1TPGE@1239,4HB0C@91061,COG2804@1,COG2804@2	NA|NA|NA	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NHHNPPIF_01077	264199.stu1866	2.7e-66	257.7	Bacilli													Bacteria	1VHC7@1239,4HS15@91061,COG4699@1,COG4699@2	NA|NA|NA	S	cog cog4699
NHHNPPIF_01078	322159.STER_1844	0.0	2382.8	Bacilli	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400				Bacteria	1TNYT@1239,4HA24@91061,COG0086@1,COG0086@2	NA|NA|NA	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHHNPPIF_01079	322159.STER_1845	0.0	2295.8	Bacilli	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400				Bacteria	1TP96@1239,4H9PK@91061,COG0085@1,COG0085@2	NA|NA|NA	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHHNPPIF_01080	264199.stu1869	0.0	1562.7	Bacilli	pbp1B		2.4.1.129,3.4.16.4	ko:K03693,ko:K05365,ko:K05366,ko:K05367,ko:K12551,ko:K12555,ko:K21464	ko00550,ko01100,ko01501,map00550,map01100,map01501		R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011		GT51		Bacteria	1TPM5@1239,4H9SA@91061,COG0744@1,COG0744@2	NA|NA|NA	M	penicillin-binding protein
NHHNPPIF_01081	264199.stu1870	2.1e-238	831.2	Bacilli	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029			iAF1260.b1637,iBWG_1329.BWG_1452,iECDH10B_1368.ECDH10B_1771,iECDH1ME8569_1439.ECDH1ME8569_1581,iECH74115_1262.ECH74115_2349,iECIAI39_1322.ECIAI39_1418,iECNA114_1301.ECNA114_1685,iECO103_1326.ECO103_1778,iECO111_1330.ECO111_2107,iECO26_1355.ECO26_2366,iECSE_1348.ECSE_1760,iECSF_1327.ECSF_1500,iECSP_1301.ECSP_2202,iECUMN_1333.ECUMN_1928,iECW_1372.ECW_m1805,iECs_1301.ECs2346,iEKO11_1354.EKO11_2137,iETEC_1333.ETEC_1672,iEcDH1_1363.EcDH1_2003,iEcE24377_1341.EcE24377A_1847,iEcHS_1320.EcHS_A1713,iEcSMS35_1347.EcSMS35_1562,iEcolC_1368.EcolC_1992,iJO1366.b1637,iSFV_1184.SFV_1654,iSF_1195.SF1662,iSSON_1240.SSON_1519,iSbBS512_1146.SbBS512_E1829,iUMNK88_1353.UMNK88_2097,iWFL_1372.ECW_m1805,iY75_1357.Y75_RS08585	Bacteria	1TPGN@1239,4H9YV@91061,COG0162@1,COG0162@2	NA|NA|NA	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NHHNPPIF_01082	322159.STER_1848	1.6e-196	691.8	Bacilli	ilvC		1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPI7@1239,4HADK@91061,COG0059@1,COG0059@2	NA|NA|NA	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NHHNPPIF_01083	264199.stu1872	1.1e-75	289.3	Bacilli	ilvN	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	M00019,M00570,M00582	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35			Bacteria	1V2AJ@1239,4HDY5@91061,COG0440@1,COG0440@2	NA|NA|NA	E	Acetolactate synthase
NHHNPPIF_01084	264199.stu1873	0.0	1104.4	Bacilli	ilvB		2.2.1.6	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	M00019,M00570,M00582	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35		iYO844.BSU28310	Bacteria	1TQE8@1239,4H9VR@91061,COG0028@1,COG0028@2	NA|NA|NA	EH	Acetolactate synthase
NHHNPPIF_01085	904306.HMPREF9192_2000	0.0	1124.0	Bacilli	ilvD		4.2.1.9	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	M00019,M00570,M00582	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35		iAF987.Gmet_1259	Bacteria	1TP1R@1239,4H9ZG@91061,COG0129@1,COG0129@2	NA|NA|NA	E	Belongs to the IlvD Edd family
NHHNPPIF_01086	264199.stu1875	6.7e-301	1039.3	Bacilli	yloV			ko:K07030					ko00000				Bacteria	1TQMX@1239,4HBSE@91061,COG1461@1,COG1461@2	NA|NA|NA	S	kinase related to dihydroxyacetone kinase
NHHNPPIF_01087	322159.STER_1855	1.8e-57	228.4	Bacilli	asp												Bacteria	1V3Q6@1239,4HHYJ@91061,COG1302@1,COG1302@2	NA|NA|NA	S	cog cog1302
NHHNPPIF_01088	322159.STER_1856	2.7e-225	787.7	Bacilli	norN			ko:K03327					ko00000,ko02000	2.A.66.1			Bacteria	1TQMT@1239,4H9Y2@91061,COG0534@1,COG0534@2	NA|NA|NA	V	Mate efflux family protein
NHHNPPIF_01089	322159.STER_1857	1.9e-278	964.5	Bacilli	thrC		4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000			iHN637.CLJU_RS16355,iIT341.HP0098	Bacteria	1TPR0@1239,4H9R7@91061,COG0498@1,COG0498@2	NA|NA|NA	E	Threonine synthase
NHHNPPIF_01090	904306.HMPREF9192_1994	2.6e-39	167.5	Bacilli	adhE		1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220		R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000			iSB619.SA_RS00885	Bacteria	1TPB4@1239,4HAN8@91061,COG1012@1,COG1012@2,COG1454@1,COG1454@2	NA|NA|NA	C	belongs to the iron- containing alcohol dehydrogenase family
NHHNPPIF_01091	264199.stu1881	2.3e-66	258.1	Bacilli	adhE		1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220		R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000			iSB619.SA_RS00885	Bacteria	1TPB4@1239,4HAN8@91061,COG1454@1,COG1454@2	NA|NA|NA	C	belongs to the iron- containing alcohol dehydrogenase family
NHHNPPIF_01092	904306.HMPREF9192_1994	1.9e-156	558.5	Bacilli	adhE		1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220		R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000			iSB619.SA_RS00885	Bacteria	1TPB4@1239,4HAN8@91061,COG1012@1,COG1012@2,COG1454@1,COG1454@2	NA|NA|NA	C	belongs to the iron- containing alcohol dehydrogenase family
NHHNPPIF_01093	264199.stu1884	1.8e-63	248.4	Bacilli	adhE		1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220		R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000			iSB619.SA_RS00885	Bacteria	1UHQT@1239,4IS6J@91061,COG1012@1,COG1012@2	NA|NA|NA	C	Dehydrogenase
NHHNPPIF_01094	322159.STER_1860	0.0	1288.1	Bacilli	pepO		3.4.24.71	ko:K01415,ko:K07386					ko00000,ko01000,ko01002,ko04147				Bacteria	1TQTA@1239,4HDSF@91061,COG3590@1,COG3590@2	NA|NA|NA	O	Peptidase family M13
NHHNPPIF_01095	264199.stu1886	1.4e-114	419.1	Bacilli	treC	GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005991,GO:0005993,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008788,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0015927,GO:0016052,GO:0016787,GO:0016798,GO:0033554,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046352,GO:0050896,GO:0051716,GO:0071704,GO:1901575	3.2.1.93	ko:K01226	ko00500,map00500		R00837,R06113	RC00049	ko00000,ko00001,ko01000		GH13	iECW_1372.ECW_m4600,iEKO11_1354.EKO11_4072,iEcE24377_1341.EcE24377A_4811,iEcSMS35_1347.EcSMS35_4720,iWFL_1372.ECW_m4600	Bacteria	1TP53@1239,4HA1G@91061,COG0366@1,COG0366@2	NA|NA|NA	G	COG0366 Glycosidases
NHHNPPIF_01096	1114965.Spaf_1558	5.5e-80	303.5	Bacilli	treC	GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005991,GO:0005993,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008788,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0015927,GO:0016052,GO:0016787,GO:0016798,GO:0033554,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046352,GO:0050896,GO:0051716,GO:0071704,GO:1901575	3.2.1.93	ko:K01226	ko00500,map00500		R00837,R06113	RC00049	ko00000,ko00001,ko01000		GH13	iECW_1372.ECW_m4600,iEKO11_1354.EKO11_4072,iEcE24377_1341.EcE24377A_4811,iEcSMS35_1347.EcSMS35_4720,iWFL_1372.ECW_m4600	Bacteria	1TP53@1239,4HA1G@91061,COG0366@1,COG0366@2	NA|NA|NA	G	COG0366 Glycosidases
NHHNPPIF_01097	264199.stu1890	1.4e-54	218.8	Bacteria	treB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0015766,GO:0015771,GO:0015772,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090589	2.7.1.201	ko:K02817,ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	M00270	R02780	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.13,4.A.1.2.4,4.A.1.2.8		iECABU_c1320.ECABU_c48060,ic_1306.c5339	Bacteria	COG1263@1,COG1263@2	NA|NA|NA	G	PTS System
NHHNPPIF_01098	264199.stu1893	8.6e-87	326.2	Bacilli	treR			ko:K03486,ko:K03710					ko00000,ko03000				Bacteria	1TRF6@1239,4HDCX@91061,COG2188@1,COG2188@2	NA|NA|NA	K	trehalose operon
NHHNPPIF_01099	322159.STER_1865	2.2e-94	351.7	Bacilli	ywlG												Bacteria	1V3H0@1239,4HH6F@91061,COG4475@1,COG4475@2	NA|NA|NA	S	Belongs to the UPF0340 family
NHHNPPIF_01102	1046629.Ssal_02110	3.2e-33	147.5	Bacilli													Bacteria	1TRSF@1239,4HDM3@91061,COG2826@1,COG2826@2	NA|NA|NA	L	PFAM Integrase, catalytic core
NHHNPPIF_01103	264199.stu1898	9.3e-72	276.2	Bacilli													Bacteria	1TRSF@1239,4HDM3@91061,COG2826@1,COG2826@2	NA|NA|NA	L	PFAM Integrase, catalytic core
NHHNPPIF_01104	264199.stu1805	2.2e-54	218.0	Bacteria	bta		1.8.1.8	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418				ko00000,ko00001,ko01000,ko03110				Bacteria	COG0526@1,COG0526@2	NA|NA|NA	CO	cell redox homeostasis
NHHNPPIF_01105	435842.HMPREF0848_01462	2.8e-13	80.9	Bacilli				ko:K07107					ko00000,ko01000				Bacteria	1VAGM@1239,4HIVC@91061,COG0824@1,COG0824@2	NA|NA|NA	L	thioesterase
NHHNPPIF_01106	264199.stu1804	7.8e-143	513.1	Bacilli													Bacteria	1TQSZ@1239,4HCXD@91061,COG2110@1,COG2110@2	NA|NA|NA	S	Macro domain protein
NHHNPPIF_01107	264199.stu1803	1.1e-50	205.7	Bacilli	trxA			ko:K03671	ko04621,ko05418,map04621,map05418				ko00000,ko00001,ko03110				Bacteria	1VA3Y@1239,4HKKX@91061,COG3118@1,COG3118@2	NA|NA|NA	O	Belongs to the thioredoxin family
NHHNPPIF_01108	264199.stu1802	1.9e-74	285.0	Bacilli	yccU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464		ko:K06929					ko00000				Bacteria	1V7C7@1239,4HIZT@91061,COG1832@1,COG1832@2	NA|NA|NA	S	CoA-binding protein
NHHNPPIF_01109	264199.stu1801	4.1e-144	517.3	Bacilli	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575		ko:K03424					ko00000,ko01000				Bacteria	1TNY1@1239,4HA74@91061,COG0084@1,COG0084@2	NA|NA|NA	L	Hydrolase, tatd
NHHNPPIF_01110	322159.STER_1773	3.2e-98	364.4	Bacilli	rnmV	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360	3.1.26.8	ko:K05985,ko:K07476					ko00000,ko01000				Bacteria	1V3K3@1239,4HH5Y@91061,COG1658@1,COG1658@2	NA|NA|NA	J	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NHHNPPIF_01111	264199.stu1799	8.9e-156	556.2	Bacilli	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528			R10716	RC00003,RC03257	ko00000,ko01000,ko03009				Bacteria	1TP9W@1239,4HA4R@91061,COG0030@1,COG0030@2	NA|NA|NA	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NHHNPPIF_01113	264199.stu1798	1.3e-162	578.9	Bacilli	rsgA		3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100		R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009				Bacteria	1TPSQ@1239,4HA9W@91061,COG1162@1,COG1162@2	NA|NA|NA	G	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NHHNPPIF_01114	264199.stu1797	1.1e-118	432.6	Bacilli	rpe		5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQK8@1239,4H9RW@91061,COG0036@1,COG0036@2	NA|NA|NA	G	Belongs to the ribulose-phosphate 3-epimerase family
NHHNPPIF_01115	264199.stu1796	9.2e-118	429.5	Bacilli	thiN		2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100		R00619	RC00002,RC00017	ko00000,ko00001,ko01000				Bacteria	1VA0W@1239,4HHS1@91061,COG1564@1,COG1564@2	NA|NA|NA	H	thiamine pyrophosphokinase
NHHNPPIF_01116	264199.stu1795	4.5e-172	610.9	Bacilli	rmuC			ko:K09760					ko00000				Bacteria	1TPWI@1239,4HE2N@91061,COG1322@1,COG1322@2	NA|NA|NA	S	RmuC domain protein
NHHNPPIF_01117	264199.stu1794	3.6e-179	634.0	Bacilli	cbf			ko:K03698					ko00000,ko01000,ko03019				Bacteria	1TPIU@1239,4HB1M@91061,COG3481@1,COG3481@2	NA|NA|NA	S	3'-5' exoribonuclease yhaM
NHHNPPIF_01118	322159.STER_1765	7e-142	510.0	Bacilli	purR		2.4.2.7	ko:K00759,ko:K09685	ko00230,ko01100,map00230,map01100		R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko03000,ko04147				Bacteria	1TPN9@1239,4HB8I@91061,COG0503@1,COG0503@2	NA|NA|NA	F	operon repressor
NHHNPPIF_01119	1046629.Ssal_00226	5.1e-69	266.9	Bacilli	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02950	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V1FJ@1239,4HFMZ@91061,COG0048@1,COG0048@2	NA|NA|NA	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NHHNPPIF_01120	1046629.Ssal_00227	4.3e-80	303.9	Bacilli	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113		ko:K02992	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V1GG@1239,4H9PA@91061,COG0049@1,COG0049@2	NA|NA|NA	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NHHNPPIF_01121	264199.stu1789	0.0	1360.5	Bacilli	fusA	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576		ko:K02355					ko00000,ko03012,ko03029				Bacteria	1TPF9@1239,4HAB8@91061,COG0480@1,COG0480@2	NA|NA|NA	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NHHNPPIF_01122	264199.stu1788	9.3e-189	666.0	Bacilli	gap	GO:0000166,GO:0002020,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009986,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019362,GO:0019637,GO:0019674,GO:0019899,GO:0022610,GO:0034641,GO:0036094,GO:0043891,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044464,GO:0044650,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051704,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0097159,GO:0140030,GO:0140032,GO:1901265,GO:1901360,GO:1901363,GO:1901564	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147				Bacteria	1TNYU@1239,4H9NS@91061,COG0057@1,COG0057@2	NA|NA|NA	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NHHNPPIF_01123	322159.STER_1413	4.1e-158	563.9	Bacilli				ko:K07497					ko00000				Bacteria	1TU21@1239,4HDK4@91061,COG2801@1,COG2801@2	NA|NA|NA	L	COG2801 Transposase and inactivated derivatives
NHHNPPIF_01124	272623.L137335	1.6e-44	186.0	Bacilli				ko:K07483					ko00000				Bacteria	1VE7W@1239,4HKEI@91061,COG2963@1,COG2963@2	NA|NA|NA	L	Transposase
NHHNPPIF_01125	904306.HMPREF9192_1949	1.7e-48	198.4	Bacilli	adk		2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1V7AW@1239,4HH8A@91061,COG0563@1,COG0563@2	NA|NA|NA	F	topology modulation protein
NHHNPPIF_01126	764298.STRMA_0446	1.7e-129	468.8	Bacilli													Bacteria	1TR5M@1239,4HCD2@91061,COG1028@1,COG1028@2	NA|NA|NA	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHHNPPIF_01127	927666.SOR_0524	9.7e-30	135.6	Streptococcus oralis													Bacteria	1TWZ1@1239,1WPY9@1303,2DJ35@1,304P3@2,4I5TZ@91061	NA|NA|NA	S	Domain of unknown function (DUF4649)
NHHNPPIF_01128	264199.stu1950	3.9e-127	461.1	Bacteria	Z012_04635												Bacteria	COG1396@1,COG1396@2	NA|NA|NA	K	sequence-specific DNA binding
NHHNPPIF_01130	264199.stu1951	3.6e-232	810.4	Firmicutes				ko:K06871					ko00000				Bacteria	1V5NX@1239,COG0641@1,COG0641@2	NA|NA|NA	C	Radical SAM
NHHNPPIF_01131	264199.stu1952	5.6e-286	989.6	Bacilli				ko:K02068,ko:K06148		M00211			ko00000,ko00002,ko02000	3.A.1			Bacteria	1VRZB@1239,4HV44@91061,COG1132@1,COG1132@2	NA|NA|NA	V	ABC transporter transmembrane region
NHHNPPIF_01132	322159.STER_1926	2.5e-89	334.7	Bacteria													Bacteria	COG1476@1,COG1476@2	NA|NA|NA	K	sequence-specific DNA binding
NHHNPPIF_01133	1403946.Q615_SPAC00126G0051	2.9e-155	554.7	Streptococcus anginosus group				ko:K07467					ko00000				Bacteria	1VMP1@1239,42EH0@671232,4HSQH@91061,COG2946@1,COG2946@2	NA|NA|NA	L	Replication initiation factor
NHHNPPIF_01134	585204.SMSK597_1426	1.9e-18	97.8	Streptococcus mitis													Bacteria	1W5B5@1239,28YJG@1,2TQ3X@28037,2ZKDA@2,4I02K@91061	NA|NA|NA	S	Domain of unknown function (DUF3173)
NHHNPPIF_01135	264199.stu1955	7.7e-216	756.1	Bacilli	int												Bacteria	1VTS1@1239,4HU1E@91061,COG0582@1,COG0582@2	NA|NA|NA	L	Belongs to the 'phage' integrase family
NHHNPPIF_01137	264199.stu1957	1.1e-236	825.5	Bacilli	rarA			ko:K07478					ko00000				Bacteria	1TPVV@1239,4HAIS@91061,COG2256@1,COG2256@2	NA|NA|NA	L	ATPase related to the helicase subunit of the Holliday junction resolvase
NHHNPPIF_01138	264199.stu1958	5.5e-26	122.9	Bacilli	rpmB	GO:0003674,GO:0003735,GO:0005198		ko:K02902	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1VEI2@1239,4HNIK@91061,COG0227@1,COG0227@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL28 family
NHHNPPIF_01139	264199.stu1959	1.4e-43	181.8	Bacilli	yrzL												Bacteria	1VAC4@1239,4HKD0@91061,COG4472@1,COG4472@2	NA|NA|NA	S	Belongs to the UPF0297 family
NHHNPPIF_01140	264199.stu1960	6.2e-70	270.0	Bacilli	yqgF	GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360		ko:K07447					ko00000,ko01000				Bacteria	1V6ER@1239,4HH04@91061,COG0816@1,COG0816@2	NA|NA|NA	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NHHNPPIF_01141	322159.STER_1939	4.2e-44	183.7	Bacilli	yrzB												Bacteria	1VAPW@1239,4HKV7@91061,COG3906@1,COG3906@2	NA|NA|NA	S	Belongs to the UPF0473 family
NHHNPPIF_01142	264199.stu1962	2.6e-297	1027.3	Bacilli	ccs												Bacteria	1V9D8@1239,2F2IJ@1,33VFI@2,4HS77@91061	NA|NA|NA	S	the current gene model (or a revised gene model) may contain a frame shift
NHHNPPIF_01143	322159.STER_1942	0.0	1499.2	Bacilli	nrdD	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0017076,GO:0018130,GO:0019001,GO:0019103,GO:0019438,GO:0019637,GO:0019692,GO:0030554,GO:0031250,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032556,GO:0032558,GO:0032559,GO:0032560,GO:0032564,GO:0032567,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0046872,GO:0046914,GO:0051065,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000			iECIAI39_1322.ECIAI39_4713,iPC815.YPO3454	Bacteria	1TR9K@1239,4HBIY@91061,COG1327@1,COG1327@2,COG1328@1,COG1328@2	NA|NA|NA	F	Ribonucleoside-triphosphate reductase
NHHNPPIF_01144	435842.HMPREF0848_01736	7.5e-14	82.0	Bacilli													Bacteria	1TXD1@1239,2DEKJ@1,2ZNBP@2,4HZYT@91061	NA|NA|NA		
NHHNPPIF_01145	322159.STER_1944	2.6e-91	341.3	Bacilli	XK27_10930												Bacteria	1V1C4@1239,4HG6C@91061,COG3981@1,COG3981@2	NA|NA|NA	K	acetyltransferase
NHHNPPIF_01146	322159.STER_1945	3.7e-116	424.1	Bacilli	nrdG	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0031250,GO:0032991,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576	1.97.1.4	ko:K04068			R04710		ko00000,ko01000			iE2348C_1286.E2348C_4563	Bacteria	1V1HG@1239,4HGJ9@91061,COG0602@1,COG0602@2	NA|NA|NA	O	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NHHNPPIF_01147	322159.STER_1946	2.4e-147	528.1	Bacilli	yaaA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700		ko:K09861					ko00000				Bacteria	1TR33@1239,4HFN2@91061,COG3022@1,COG3022@2	NA|NA|NA	S	Belongs to the UPF0246 family
NHHNPPIF_01148	322159.STER_1947	9.9e-169	599.4	Bacilli	XK27_01785												Bacteria	1TRBT@1239,4HBPR@91061,COG1284@1,COG1284@2	NA|NA|NA	S	cog cog1284
NHHNPPIF_01149	322159.STER_1948	0.0	1144.4	Bacilli	aspS		6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029				Bacteria	1TPCN@1239,4HACD@91061,COG0173@1,COG0173@2	NA|NA|NA	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NHHNPPIF_01151	322159.STER_1950	1.6e-241	841.6	Bacilli	hisS		6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1TP3D@1239,4HAM2@91061,COG0124@1,COG0124@2	NA|NA|NA	J	histidyl-tRNA synthetase
NHHNPPIF_01152	1046629.Ssal_00053	5.7e-52	209.9	Bacilli	metE		2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPDQ@1239,4HADW@91061,COG0620@1,COG0620@2	NA|NA|NA	E	Methionine synthase
NHHNPPIF_01153	1046629.Ssal_00053	7.6e-64	249.6	Bacilli	metE		2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPDQ@1239,4HADW@91061,COG0620@1,COG0620@2	NA|NA|NA	E	Methionine synthase
NHHNPPIF_01154	1046629.Ssal_00053	9.2e-36	155.6	Bacilli	metE		2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPDQ@1239,4HADW@91061,COG0620@1,COG0620@2	NA|NA|NA	E	Methionine synthase
NHHNPPIF_01155	1123315.AUIP01000010_gene919	2e-25	120.9	Bacilli	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904		ko:K02911	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011,ko03029				Bacteria	1VKMZ@1239,4HR2Q@91061,COG0333@1,COG0333@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL32 family
NHHNPPIF_01156	1046629.Ssal_00051	6.7e-19	99.0	Bacteria	rpmG	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02913	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	COG0267@1,COG0267@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL33 family
NHHNPPIF_01159	1069533.Sinf_1920	3.9e-115	421.0	Firmicutes	yegS	GO:0001727,GO:0003674,GO:0003824,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0030258,GO:0044237,GO:0044238,GO:0044255,GO:0046834,GO:0071704	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110		R02240	RC00002,RC00017	ko00000,ko00001,ko01000				Bacteria	1TQ9A@1239,COG1597@1,COG1597@2	NA|NA|NA	I	Diacylglycerol kinase
NHHNPPIF_01160	1069533.Sinf_1920	2.9e-15	87.0	Firmicutes	yegS	GO:0001727,GO:0003674,GO:0003824,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0030258,GO:0044237,GO:0044238,GO:0044255,GO:0046834,GO:0071704	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110		R02240	RC00002,RC00017	ko00000,ko00001,ko01000				Bacteria	1TQ9A@1239,COG1597@1,COG1597@2	NA|NA|NA	I	Diacylglycerol kinase
NHHNPPIF_01161	264199.stu1980	3.6e-95	354.4	Firmicutes													Bacteria	1TRFZ@1239,COG1808@1,COG1808@2	NA|NA|NA	S	Hydrophobic domain protein
NHHNPPIF_01163	322159.STER_1260	1.5e-10	70.9	Bacilli	XK27_01265			ko:K16923		M00582			ko00000,ko00002,ko02000	3.A.1.28			Bacteria	1VC0F@1239,4HMJM@91061,COG4720@1,COG4720@2	NA|NA|NA	S	ECF-type riboflavin transporter, S component
NHHNPPIF_01164	264199.stu1284	9.3e-87	326.2	Bacilli	pdxK		2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100		R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000				Bacteria	1TRCR@1239,4HHME@91061,COG2240@1,COG2240@2	NA|NA|NA	H	Belongs to the pyridoxine kinase family
NHHNPPIF_01165	264199.stu1284	5.5e-42	176.8	Bacilli	pdxK		2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100		R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000				Bacteria	1TRCR@1239,4HHME@91061,COG2240@1,COG2240@2	NA|NA|NA	H	Belongs to the pyridoxine kinase family
NHHNPPIF_01166	264199.stu1285	2e-86	325.1	Firmicutes													Bacteria	1V6QK@1239,COG4720@1,COG4720@2	NA|NA|NA	S	ECF-type riboflavin transporter, S component
NHHNPPIF_01168	322159.STER_1264	7.7e-241	839.3	Bacilli	XK27_08130												Bacteria	1TPS5@1239,4HBNK@91061,COG1167@1,COG1167@2	NA|NA|NA	K	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NHHNPPIF_01169	264199.stu1289	2e-55	221.5	Firmicutes	nrdD_1		1.1.98.6,1.17.4.1	ko:K00525,ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024,R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400				Bacteria	1TT3U@1239,COG0209@1,COG0209@2	NA|NA|NA	F	Ribonucleoside-triphosphate reductase
NHHNPPIF_01171	322159.STER_1267	0.0	1535.0	Bacilli	pheT	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890,ko:K06878	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iG2583_1286.G2583_2160,iPC815.YPO2428	Bacteria	1TP98@1239,4HAQ9@91061,COG0072@1,COG0072@2,COG0073@1,COG0073@2	NA|NA|NA	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NHHNPPIF_01172	264199.stu1293	3.8e-93	347.4	Bacilli	paiA		2.3.1.57	ko:K22441					ko00000,ko01000				Bacteria	1VDFK@1239,4HMHW@91061,COG0454@1,COG0456@2	NA|NA|NA	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHHNPPIF_01173	264199.stu1294	9.6e-197	692.6	Bacilli	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1TPFW@1239,4HAVN@91061,COG0016@1,COG0016@2	NA|NA|NA	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NHHNPPIF_01174	264199.stu1295	0.0	1470.3	Bacilli	smc			ko:K03529					ko00000,ko03036				Bacteria	1TPJV@1239,4HB89@91061,COG1196@1,COG1196@2	NA|NA|NA	D	Required for chromosome condensation and partitioning
NHHNPPIF_01175	264199.stu1296	1.9e-124	451.8	Bacilli	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205				ko00000,ko00001,ko01000,ko03009,ko03019,ko03036				Bacteria	1TPGC@1239,4HAWU@91061,COG0571@1,COG0571@2	NA|NA|NA	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NHHNPPIF_01176	322159.STER_1273	6.6e-173	613.2	Bacilli	dapA		4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPCK@1239,4H9K9@91061,COG0329@1,COG0329@2	NA|NA|NA	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHHNPPIF_01177	322159.STER_1274	3.1e-198	697.6	Bacilli	asd		1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPC6@1239,4HA9H@91061,COG0136@1,COG0136@2	NA|NA|NA	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NHHNPPIF_01178	322159.STER_1275	1.7e-78	298.5	Bacteria	alkD												Bacteria	COG4912@1,COG4912@2	NA|NA|NA	L	Dna alkylation repair
NHHNPPIF_01179	322159.STER_1276	2.8e-93	347.8	Bacilli	pat		2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130		R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000				Bacteria	1V6X5@1239,4HIP1@91061,COG1247@1,COG1247@2	NA|NA|NA	M	acetyltransferase
NHHNPPIF_01180	1046629.Ssal_00208	1.6e-11	75.1	Firmicutes													Bacteria	1TQ93@1239,COG3464@1,COG3464@2	NA|NA|NA	L	Transposase
NHHNPPIF_01183	264199.stu1242	5.6e-205	719.9	Bacilli	rfbB	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901576	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPWM@1239,4HA3Y@91061,COG1088@1,COG1088@2	NA|NA|NA	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NHHNPPIF_01184	264199.stu1243	2.7e-111	407.9	Bacilli	rmlC		1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000				Bacteria	1TRVB@1239,4HFQB@91061,COG1898@1,COG1898@2	NA|NA|NA	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NHHNPPIF_01185	264199.stu1244	5.4e-161	573.5	Bacilli	rfbA	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005996,GO:0006006,GO:0006139,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009117,GO:0009141,GO:0009147,GO:0009200,GO:0009211,GO:0009219,GO:0009225,GO:0009226,GO:0009262,GO:0009394,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019299,GO:0019300,GO:0019305,GO:0019318,GO:0019319,GO:0019438,GO:0019637,GO:0019692,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0045226,GO:0046075,GO:0046364,GO:0046379,GO:0046383,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000			iNJ661.Rv0334	Bacteria	1V301@1239,4H9R0@91061,COG1209@1,COG1209@2	NA|NA|NA	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NHHNPPIF_01186	264199.stu1245	1.7e-204	718.4	Bacilli	yurR	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114	1.4.5.1	ko:K00285	ko00360,map00360		R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000				Bacteria	1TQTF@1239,4HA0F@91061,COG0665@1,COG0665@2	NA|NA|NA	E	oxidoreductase
NHHNPPIF_01187	1046629.Ssal_01342	1.6e-101	375.6	Bacilli	zupT			ko:K07238					ko00000,ko02000	2.A.5.5			Bacteria	1TP7J@1239,4HB3R@91061,COG0428@1,COG0428@2	NA|NA|NA	P	Mediates zinc uptake. May also transport other divalent cations
NHHNPPIF_01188	1046629.Ssal_01342	7e-22	109.4	Bacilli	zupT			ko:K07238					ko00000,ko02000	2.A.5.5			Bacteria	1TP7J@1239,4HB3R@91061,COG0428@1,COG0428@2	NA|NA|NA	P	Mediates zinc uptake. May also transport other divalent cations
NHHNPPIF_01189	264199.stu1248	9.6e-149	532.7	Bacilli	yqfO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.5.4.16	ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQ27@1239,4H9NY@91061,COG0327@1,COG0327@2	NA|NA|NA	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NHHNPPIF_01190	264199.stu1249	3.5e-123	447.6	Bacilli	trmK	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.217	ko:K06967					ko00000,ko01000,ko03016				Bacteria	1V3I4@1239,4HHIM@91061,COG2384@1,COG2384@2	NA|NA|NA	S	SAM-dependent methyltransferase
NHHNPPIF_01191	264199.stu1250	1.3e-70	272.3	Bacilli	gtrA	GO:0000166,GO:0003674,GO:0003824,GO:0003870,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009987,GO:0016020,GO:0016410,GO:0016491,GO:0016620,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0016903,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576											Bacteria	1VMS6@1239,4HNB7@91061,COG2246@1,COG2246@2	NA|NA|NA	S	GtrA-like protein
NHHNPPIF_01192	264199.stu1251	8.2e-249	865.9	Bacilli	glmM	GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130		R02060	RC00408	ko00000,ko00001,ko01000			iSB619.SA_RS11275,iSBO_1134.SBO_3206	Bacteria	1TP1X@1239,4HB16@91061,COG1109@1,COG1109@2	NA|NA|NA	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NHHNPPIF_01193	322159.STER_1231	4.3e-167	594.0	Bacilli	ybbR	GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009											Bacteria	1TSIV@1239,4HD8Y@91061,COG4856@1,COG4856@2	NA|NA|NA	S	Protein conserved in bacteria
NHHNPPIF_01194	264199.stu1253	2.8e-123	448.0	Bacilli	dacA	GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	2.7.7.85	ko:K18672					ko00000,ko01000				Bacteria	1TPRW@1239,4H9XZ@91061,COG1624@1,COG1624@2	NA|NA|NA	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NHHNPPIF_01195	264199.stu1254	1.8e-253	881.3	Bacilli	murD		3.4.21.10,6.3.2.13,6.3.2.9	ko:K01317,ko:K01925,ko:K01928,ko:K01932	ko00300,ko00471,ko00550,ko01100,map00300,map00471,map00550,map01100		R02783,R02788	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01002,ko01011,ko04131				Bacteria	1UHPI@1239,4HVP0@91061,COG0771@1,COG0771@2	NA|NA|NA	M	Mur ligase, middle domain protein
NHHNPPIF_01196	264199.stu1255	3.3e-149	534.3	Bacilli	cobQ			ko:K07009					ko00000				Bacteria	1U7I9@1239,4HD1P@91061,COG3442@1,COG3442@2	NA|NA|NA	S	glutamine amidotransferase
NHHNPPIF_01197	264199.stu1256	0.0	1646.3	Bacilli	mprF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.3.2.3	ko:K07027,ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726			ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	2.A.1.3.37,4.D.2		iYO844.BG12900	Bacteria	1TQI2@1239,4HBHU@91061,COG0392@1,COG0392@2,COG2898@1,COG2898@2	NA|NA|NA	J	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NHHNPPIF_01198	264199.stu1257	3.1e-130	471.1	Bacilli	pip		1.11.1.10	ko:K00433					ko00000,ko01000				Bacteria	1V02M@1239,4HN2K@91061,COG0596@1,COG0596@2	NA|NA|NA	S	Alpha beta hydrolase
NHHNPPIF_01200	264199.stu1259	0.0	1203.3	Bacilli	uup			ko:K06158					ko00000,ko03012				Bacteria	1TPAX@1239,4HBVV@91061,COG0488@1,COG0488@2	NA|NA|NA	S	abc transporter atp-binding protein
NHHNPPIF_01201	264199.stu1260	6.2e-114	416.8	Bacilli	udk	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100		R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000			iSBO_1134.SBO_0893	Bacteria	1TQ4V@1239,4HAVR@91061,COG0572@1,COG0572@2	NA|NA|NA	F	Cytidine monophosphokinase
NHHNPPIF_01202	322159.STER_1239	1.5e-176	625.5	Bacilli	yfmL	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K05592,ko:K18692	ko03018,map03018				ko00000,ko00001,ko01000,ko03009,ko03019				Bacteria	1TQ9R@1239,4HANR@91061,COG0513@1,COG0513@2	NA|NA|NA	L	DEAD DEAH box helicase
NHHNPPIF_01203	322159.STER_1240	4.8e-28	129.8	Bacteria			6.3.2.2,6.3.2.4	ko:K01919,ko:K01921	ko00270,ko00473,ko00480,ko00550,ko01100,ko01502,map00270,map00473,map00480,map00550,map01100,map01502	M00118	R00894,R01150,R10993	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011				Bacteria	COG1181@1,COG1181@2	NA|NA|NA	F	Belongs to the D-alanine--D-alanine ligase family
NHHNPPIF_01204	264199.stu1263	1.9e-264	917.9	Bacilli	gapN	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0043891,GO:0047100,GO:0055114	1.2.1.9	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	M00308,M00633	R01058	RC00242	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP4S@1239,4H9MF@91061,COG1012@1,COG1012@2	NA|NA|NA	C	Belongs to the aldehyde dehydrogenase family
NHHNPPIF_01205	264199.stu1264	0.0	1087.4	Bacilli	ptsI	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0008150,GO:0008643,GO:0008965,GO:0009401,GO:0016740,GO:0016772,GO:0016775,GO:0019197,GO:0032991,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051179,GO:0051234,GO:0071702	2.7.3.9	ko:K08483	ko02060,map02060				ko00000,ko00001,ko01000,ko02000	8.A.7		iB21_1397.B21_02277,iE2348C_1286.E2348C_2602,iEC042_1314.EC042_2625,iECBD_1354.ECBD_1265,iECB_1328.ECB_02316,iECD_1391.ECD_02316,iECH74115_1262.ECH74115_3647,iECIAI1_1343.ECIAI1_2474,iECIAI39_1322.ECIAI39_2562,iECO103_1326.ECO103_2935,iECO111_1330.ECO111_3146,iECO26_1355.ECO26_3469,iECP_1309.ECP_2440,iECSE_1348.ECSE_2707,iECSP_1301.ECSP_3364,iECUMN_1333.ECUMN_2738,iECW_1372.ECW_m2645,iECs_1301.ECs3288,iEKO11_1354.EKO11_1312,iEcE24377_1341.EcE24377A_2703,iEcHS_1320.EcHS_A2551,iEcSMS35_1347.EcSMS35_2571,iEcolC_1368.EcolC_1262,iLF82_1304.LF82_1770,iNRG857_1313.NRG857_12115,iSBO_1134.SBO_2440,iSDY_1059.SDY_2613,iSFV_1184.SFV_2468,iSF_1195.SF2471,iSFxv_1172.SFxv_2720,iSSON_1240.SSON_2505,iS_1188.S2617,iUMNK88_1353.UMNK88_3018,iWFL_1372.ECW_m2645,iZ_1308.Z3682	Bacteria	1TPK8@1239,4H9VD@91061,COG1080@1,COG1080@2	NA|NA|NA	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NHHNPPIF_01206	264199.stu1265	7.9e-39	166.0	Bacilli	ptsH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007		ko:K11189					ko00000,ko02000	4.A.2.1			Bacteria	1VA0R@1239,4HKGA@91061,COG1925@1,COG1925@2	NA|NA|NA	G	phosphocarrier protein Hpr
NHHNPPIF_01207	264199.stu1266	8.2e-221	772.7	Bacilli	icd	GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000			e_coli_core.b1136,iAF1260.b1136,iECDH1ME8569_1439.ECDH1ME8569_1071,iEcDH1_1363.EcDH1_2511,iJN746.PP_4011,iJO1366.b1136,iJR904.b1136,iY75_1357.Y75_RS05930,iYL1228.KPN_01144	Bacteria	1UHPE@1239,4H9US@91061,COG0538@1,COG0538@2	NA|NA|NA	C	Isocitrate dehydrogenase
NHHNPPIF_01208	264199.stu1267	5.1e-212	743.4	Bacilli	citZ		2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	1TPPS@1239,4H9YE@91061,COG0372@1,COG0372@2	NA|NA|NA	C	Belongs to the citrate synthase family
NHHNPPIF_01209	264199.stu1268	0.0	1746.9	Bacilli	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000			iSB619.SA_RS06730	Bacteria	1VTMM@1239,4HB5N@91061,COG1048@1,COG1048@2	NA|NA|NA	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NHHNPPIF_01210	264199.stu1269	8.5e-34	149.1	Bacilli	nrdH	GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009893,GO:0009987,GO:0016491,GO:0019222,GO:0019725,GO:0022900,GO:0042592,GO:0043085,GO:0044093,GO:0044237,GO:0045454,GO:0048518,GO:0050789,GO:0050790,GO:0050794,GO:0051341,GO:0051353,GO:0055114,GO:0065007,GO:0065008,GO:0065009		ko:K06191					ko00000				Bacteria	1VEFX@1239,4HNUX@91061,COG0695@1,COG0695@2	NA|NA|NA	O	Glutaredoxin
NHHNPPIF_01211	264199.stu1270	0.0	1439.5	Bacilli	nrdE		1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400			iYO844.BSU17380	Bacteria	1TPFH@1239,4H9X0@91061,COG0209@1,COG0209@2	NA|NA|NA	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHHNPPIF_01212	264199.stu1271	8.6e-184	649.4	Bacilli	nrdF		1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400				Bacteria	1TQTH@1239,4H9WX@91061,COG0208@1,COG0208@2	NA|NA|NA	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHHNPPIF_01214	264199.stu1273	4.2e-71	273.9	Bacteria													Bacteria	COG3547@1,COG3547@2	NA|NA|NA	L	Transposase (IS116 IS110 IS902 family)
NHHNPPIF_01215	264199.stu1274	8.8e-60	236.1	Bacteria													Bacteria	COG3547@1,COG3547@2	NA|NA|NA	L	Transposase (IS116 IS110 IS902 family)
NHHNPPIF_01216	264199.stu1275	5.3e-165	587.0	Bacilli	ypuA												Bacteria	1TR2I@1239,4HBVZ@91061,COG4086@1,COG4086@2	NA|NA|NA	S	secreted protein
NHHNPPIF_01217	264199.stu1276	1.5e-52	211.8	Firmicutes	yaeR			ko:K08234					ko00000				Bacteria	1V6XU@1239,COG0346@1,COG0346@2	NA|NA|NA	E	COG0346 LactoylglutaTHIone lyase and related lyases
NHHNPPIF_01218	322159.STER_1255	1.6e-132	478.8	Bacilli	srtA		3.4.22.70	ko:K07284					ko00000,ko01000,ko01002,ko01011				Bacteria	1V83Z@1239,4HIA0@91061,COG3764@1,COG3764@2	NA|NA|NA	M	Sortase (surface protein transpeptidase)
NHHNPPIF_01219	322159.STER_1256	0.0	1413.3	Bacilli	gyrA	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	5.99.1.3	ko:K02469,ko:K02621					ko00000,ko01000,ko02048,ko03032,ko03036,ko03400				Bacteria	1TP2Z@1239,4HAHY@91061,COG0188@1,COG0188@2	NA|NA|NA	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHHNPPIF_01220	264199.stu1280	1.6e-180	638.6	Bacilli	ldh		1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922		R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147				Bacteria	1TPSY@1239,4HB0Z@91061,COG0039@1,COG0039@2	NA|NA|NA	C	Belongs to the LDH MDH superfamily. LDH family
NHHNPPIF_01221	322159.STER_1258	8.3e-257	892.5	Bacilli	noxE												Bacteria	1TPWW@1239,4H9U7@91061,COG0446@1,COG0446@2	NA|NA|NA	P	NADH oxidase
NHHNPPIF_01222	322159.STER_1259	3.6e-293	1013.4	Bacilli	yfmM			ko:K06158					ko00000,ko03012				Bacteria	1TPAX@1239,4HC58@91061,COG0488@1,COG0488@2	NA|NA|NA	S	abc transporter atp-binding protein
NHHNPPIF_01223	322159.STER_1260	4.8e-59	233.8	Bacilli	XK27_01265			ko:K16923		M00582			ko00000,ko00002,ko02000	3.A.1.28			Bacteria	1VC0F@1239,4HMJM@91061,COG4720@1,COG4720@2	NA|NA|NA	S	ECF-type riboflavin transporter, S component
NHHNPPIF_01224	1069533.Sinf_0805	1.5e-37	161.8	Bacteria				ko:K07483					ko00000				Bacteria	COG2963@1,COG2963@2	NA|NA|NA	L	transposase activity
NHHNPPIF_01225	264199.stu1392	0.0	1404.4	Bacilli													Bacteria	1VATJ@1239,4HG1M@91061,COG1216@1,COG1216@2,COG1442@1,COG1442@2	NA|NA|NA	M	family 8
NHHNPPIF_01226	1027396.LMOSA_12070	0.0	1075.5	Listeriaceae	hsdM		2.1.1.72	ko:K03427					ko00000,ko01000,ko02048				Bacteria	1TPGZ@1239,26IQ9@186820,4HA1J@91061,COG0286@1,COG0286@2	NA|NA|NA	V	Type I restriction-modification system
NHHNPPIF_01227	1316408.HSISM1_1027	1.1e-74	287.3	Bacteria	hsdS		3.1.21.3	ko:K01154					ko00000,ko01000,ko02048				Bacteria	COG0732@1,COG0732@2	NA|NA|NA	V	type I restriction modification DNA specificity domain
NHHNPPIF_01228	345219.Bcoa_1815	0.0	1384.4	Bacillus			3.1.21.3	ko:K01153					ko00000,ko01000,ko02048				Bacteria	1TP7S@1239,1ZCG9@1386,4HB5A@91061,COG0610@1,COG0610@2	NA|NA|NA	L	Subunit R is required for both nuclease and ATPase activities, but not for modification
NHHNPPIF_01230	862970.SAIN_0151	9.4e-11	72.8	Streptococcus anginosus group													Bacteria	1TVY9@1239,29H5Y@1,3043H@2,42EEJ@671232,4I4K4@91061	NA|NA|NA		
NHHNPPIF_01231	264199.stu1386	8.5e-117	427.2	Bacilli													Bacteria	1VBXK@1239,2CWIF@1,32SZQ@2,4HWJ5@91061	NA|NA|NA		
NHHNPPIF_01232	322159.STER_1339	4.2e-264	916.8	Bacilli	uvrX		2.7.7.7	ko:K02346,ko:K03502,ko:K14161					ko00000,ko01000,ko03400				Bacteria	1TP42@1239,4HA1P@91061,COG0389@1,COG0389@2	NA|NA|NA	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHHNPPIF_01233	264199.stu1384	3.2e-59	234.2	Bacilli													Bacteria	1VFMU@1239,2E59Z@1,33028@2,4HQG9@91061	NA|NA|NA		
NHHNPPIF_01235	904306.HMPREF9192_1034	2.7e-71	274.6	Bacilli													Bacteria	1V0E0@1239,2EXVW@1,33R50@2,4HBMI@91061	NA|NA|NA	S	Signal peptide protein, YSIRK family
NHHNPPIF_01236	1203590.HMPREF1481_01686	4.8e-55	220.3	Bacilli													Bacteria	1V4S4@1239,4HH0U@91061,COG0745@1,COG0745@2	NA|NA|NA	K	response regulator
NHHNPPIF_01238	322159.STER_1332	3e-284	983.8	Bacilli	XK27_07020												Bacteria	1TQYE@1239,4HDNX@91061,COG4868@1,COG4868@2	NA|NA|NA	S	Belongs to the UPF0371 family
NHHNPPIF_01239	904306.HMPREF9192_1063	2.6e-180	637.9	Bacilli	galE		5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQ7N@1239,4H9U5@91061,COG1087@1,COG1087@2	NA|NA|NA	M	Belongs to the NAD(P)-dependent epimerase dehydratase family
NHHNPPIF_01240	322159.STER_1326	8.4e-159	566.2	Bacilli	yvgN												Bacteria	1TPM1@1239,4HARE@91061,COG0656@1,COG0656@2	NA|NA|NA	C	reductase
NHHNPPIF_01241	904306.HMPREF9192_1065	8.1e-27	125.9	Firmicutes	yoaK												Bacteria	1V9ME@1239,COG3619@1,COG3619@2	NA|NA|NA	S	Protein of unknown function (DUF1275)
NHHNPPIF_01242	322159.STER_1325	8.2e-68	263.1	Firmicutes	yoaK												Bacteria	1V9ME@1239,COG3619@1,COG3619@2	NA|NA|NA	S	Protein of unknown function (DUF1275)
NHHNPPIF_01243	264199.stu1369	2.2e-111	408.3	Bacilli	drgA												Bacteria	1UYJU@1239,4HBVQ@91061,COG0778@1,COG0778@2	NA|NA|NA	C	Nitroreductase
NHHNPPIF_01244	322159.STER_1323	1.9e-231	808.1	Bacilli	pts13C			ko:K02761	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.3.2			Bacteria	1V5SI@1239,4HJTK@91061,COG1455@1,COG1455@2	NA|NA|NA	G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHHNPPIF_01245	322159.STER_1322	1.6e-157	562.0	Bacilli													Bacteria	1V13S@1239,4HENM@91061,COG4814@1,COG4814@2	NA|NA|NA	E	Alpha/beta hydrolase of unknown function (DUF915)
NHHNPPIF_01246	264199.stu1366	4.7e-76	290.4	Bacilli	ywnA												Bacteria	1V6FK@1239,4HKZD@91061,COG1959@1,COG1959@2	NA|NA|NA	K	Transcriptional regulator
NHHNPPIF_01247	1046629.Ssal_00336	1.6e-12	77.4	Bacteria													Bacteria	COG3464@1,COG3464@2	NA|NA|NA		
NHHNPPIF_01250	435842.HMPREF0848_01529	5.3e-16	89.4	Bacteria													Bacteria	2C0H5@1,2ZRTJ@2	NA|NA|NA		
NHHNPPIF_01251	322159.STER_0258	2.2e-54	218.0	Bacilli													Bacteria	1VKEZ@1239,4HS74@91061,COG2314@1,COG2314@2	NA|NA|NA	S	TM2 domain
NHHNPPIF_01252	264199.stu0211	3.1e-164	584.3	Bacilli	rluA	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180					ko00000,ko01000,ko03009				Bacteria	1TSM6@1239,4HA7M@91061,COG0564@1,COG0564@2	NA|NA|NA	J	Responsible for synthesis of pseudouridine from uracil
NHHNPPIF_01253	264199.stu0212	0.0	1503.4	Bacilli	pbp2A		2.4.1.129,3.4.16.4	ko:K03693,ko:K05365,ko:K05366,ko:K12555,ko:K21464	ko00550,ko01100,ko01501,map00550,map01100,map01501		R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011		GT51		Bacteria	1TPM5@1239,4H9SA@91061,COG0744@1,COG0744@2	NA|NA|NA	M	penicillin-binding protein
NHHNPPIF_01254	264199.stu0213	3.3e-21	106.7	Bacteria	rpmG			ko:K02913	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	COG0267@1,COG0267@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL33 family
NHHNPPIF_01255	904306.HMPREF9192_0204	2.2e-24	117.5	Firmicutes	secE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944		ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2			Bacteria	1W4QH@1239,COG0690@1,COG0690@2	NA|NA|NA	U	Belongs to the SecE SEC61-gamma family
NHHNPPIF_01256	1046629.Ssal_01967	8.4e-96	356.3	Bacilli	nusG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141		ko:K02601					ko00000,ko03009,ko03021				Bacteria	1TR3P@1239,4HAJA@91061,COG0250@1,COG0250@2	NA|NA|NA	K	Participates in transcription elongation, termination and antitermination
NHHNPPIF_01257	264199.stu0216	4.6e-85	320.5	Bacteria			3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27	ko:K01096,ko:K19302	ko00550,ko00564,ko01100,map00550,map00564,map01100		R02029,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011				Bacteria	COG0671@1,COG0671@2	NA|NA|NA	I	phosphatidate phosphatase activity
NHHNPPIF_01258	264199.stu0217	4e-47	193.7	Bacteria	cof												Bacteria	COG0561@1,COG0561@2	NA|NA|NA	Q	phosphatase activity
NHHNPPIF_01259	264199.stu0218	2.1e-35	154.5	Bacteria	cof												Bacteria	COG0561@1,COG0561@2	NA|NA|NA	Q	phosphatase activity
NHHNPPIF_01260	264199.stu0219	8.7e-99	366.3	Bacilli	glcR			ko:K02444,ko:K22103					ko00000,ko03000				Bacteria	1V6VV@1239,4HK1E@91061,COG1349@1,COG1349@2	NA|NA|NA	K	transcriptional regulator (DeoR family)
NHHNPPIF_01261	264199.stu0220	0.0	1707.6	Bacilli	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029				Bacteria	1TP0Y@1239,4HAG1@91061,COG0495@1,COG0495@2	NA|NA|NA	J	Belongs to the class-I aminoacyl-tRNA synthetase family
NHHNPPIF_01263	1046629.Ssal_01959	2e-24	117.9	Bacilli				ko:K06889					ko00000				Bacteria	1V38K@1239,4HE7V@91061,COG1073@1,COG1073@2	NA|NA|NA	S	COG1073 Hydrolases of the alpha beta superfamily
NHHNPPIF_01264	1095726.HMPREF1116_1200	8.3e-126	456.4	Bacilli				ko:K06889					ko00000				Bacteria	1V38K@1239,4HE7V@91061,COG1073@1,COG1073@2	NA|NA|NA	S	COG1073 Hydrolases of the alpha beta superfamily
NHHNPPIF_01265	264199.stu0226	3.2e-275	953.7	Bacilli	pncB	GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100		R01724	RC00033	ko00000,ko00001,ko01000			iYO844.BSU31750	Bacteria	1TPDW@1239,4HAI4@91061,COG1488@1,COG1488@2	NA|NA|NA	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NHHNPPIF_01266	264199.stu0227	2.1e-151	541.6	Bacilli	nadE	GO:0003674,GO:0003824,GO:0003952,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0033554,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000			iECSE_1348.ECSE_1910,iECW_1372.ECW_m1909,iEKO11_1354.EKO11_2035,iETEC_1333.ETEC_1772,iEcE24377_1341.EcE24377A_1961,iSFV_1184.SFV_1480,iSF_1195.SF1486,iSFxv_1172.SFxv_1676,iSSON_1240.SSON_1418,iS_1188.S1603,iWFL_1372.ECW_m1909	Bacteria	1TQ38@1239,4HA2R@91061,COG0171@1,COG0171@2	NA|NA|NA	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NHHNPPIF_01267	264199.stu0228	3.2e-77	294.3	Bacteria	yhaI												Bacteria	COG3152@1,COG3152@2	NA|NA|NA	L	Membrane
NHHNPPIF_01268	264199.stu0229	5.1e-259	899.8	Bacilli	pepC	GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.4.22.40	ko:K01372					ko00000,ko01000,ko01002				Bacteria	1TRJN@1239,4HBZ9@91061,COG3579@1,COG3579@2	NA|NA|NA	E	aminopeptidase
NHHNPPIF_01269	264199.stu0230	0.0	1389.0	Bacilli	ponA	GO:0005575,GO:0005576	2.4.1.129,3.4.16.4	ko:K03693,ko:K05365,ko:K05366,ko:K12555,ko:K21464	ko00550,ko01100,ko01501,map00550,map01100,map01501		R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011		GT51		Bacteria	1TPM5@1239,4H9SA@91061,COG0744@1,COG0744@2	NA|NA|NA	M	penicillin-binding protein
NHHNPPIF_01270	264199.stu0231	2.5e-109	401.4	Bacilli	recU	GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360		ko:K03700					ko00000,ko03400				Bacteria	1V3S4@1239,4HGZ7@91061,COG3331@1,COG3331@2	NA|NA|NA	L	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NHHNPPIF_01271	322159.STER_0279	3.1e-95	354.4	Bacilli	ypsA												Bacteria	1V5Q7@1239,4HECZ@91061,COG4474@1,COG4474@2	NA|NA|NA	S	Belongs to the UPF0398 family
NHHNPPIF_01272	264199.stu0233	7.3e-50	203.0	Bacilli	gpsB			ko:K04074					ko00000,ko03036				Bacteria	1VEQ4@1239,4HKUX@91061,COG3599@1,COG3599@2	NA|NA|NA	D	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NHHNPPIF_01273	264199.stu0234	3.3e-222	777.3	Bacilli	rlmL	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016423,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.173,2.1.1.264	ko:K07444,ko:K12297			R07234	RC00003	ko00000,ko01000,ko03009				Bacteria	1TP0X@1239,4HBKY@91061,COG0116@1,COG0116@2	NA|NA|NA	L	Belongs to the methyltransferase superfamily
NHHNPPIF_01274	322159.STER_0283	4.7e-303	1046.6	Bacilli	mapZ			ko:K20073					ko00000				Bacteria	1VDPS@1239,2DB6P@1,32TWV@2,4HK8Y@91061	NA|NA|NA	D	Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
NHHNPPIF_01275	322159.STER_0284	0.0	2030.4	Bacilli	snf		2.7.11.1	ko:K08282					ko00000,ko01000				Bacteria	1TPFZ@1239,4HAIF@91061,COG0553@1,COG0553@2	NA|NA|NA	L	Superfamily II DNA RNA helicases, SNF2 family'
NHHNPPIF_01276	40041.SZO_03140	2.5e-23	115.9	Streptococcus dysgalactiae group													Bacteria	1M9KI@119603,1TXB8@1239,2DJ6Z@1,304WH@2,4I68V@91061	NA|NA|NA		
NHHNPPIF_01277	264199.stu0239	2.6e-255	887.5	Bacilli	mpl	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0042802,GO:0044424,GO:0044464	6.3.2.4,6.3.2.45,6.3.2.8	ko:K01921,ko:K01924,ko:K02558	ko00471,ko00473,ko00550,ko01100,ko01502,map00471,map00473,map00550,map01100,map01502		R01150,R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011			iSDY_1059.SDY_4251	Bacteria	1TQ5H@1239,4HAR4@91061,COG0773@1,COG0773@2	NA|NA|NA	M	Belongs to the MurCDEF family
NHHNPPIF_01278	264199.stu0240	5.6e-52	209.9	Bacteria	XK27_09675			ko:K07105					ko00000				Bacteria	COG0454@1,COG0454@2	NA|NA|NA	K	-acetyltransferase
NHHNPPIF_01279	322159.STER_0288	0.0	1187.2	Bacilli	mltG			ko:K07082					ko00000				Bacteria	1TS48@1239,4HAUV@91061,COG1559@1,COG1559@2	NA|NA|NA	ADL	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NHHNPPIF_01280	322159.STER_0289	4.6e-77	293.9	Bacilli	greA	GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576		ko:K03624					ko00000,ko03021				Bacteria	1V44S@1239,4HGZU@91061,COG0782@1,COG0782@2	NA|NA|NA	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NHHNPPIF_01281	322159.STER_0291	2.6e-88	331.3	Firmicutes				ko:K07497					ko00000				Bacteria	1TQQY@1239,COG2801@1,COG2801@2	NA|NA|NA	L	Integrase core domain protein
NHHNPPIF_01282	264199.stu0245	2.9e-165	587.8	Bacilli	yidC			ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9			Bacteria	1TSDN@1239,4HCC8@91061,COG0706@1,COG0706@2	NA|NA|NA	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NHHNPPIF_01283	264199.stu0246	6e-45	186.4	Bacteria	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120		R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000			iSB619.SA_RS07020,iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036	Bacteria	COG1254@1,COG1254@2	NA|NA|NA	C	Belongs to the acylphosphatase family
NHHNPPIF_01284	264199.stu0247	1.9e-130	471.9	Bacilli	spoU		2.1.1.185	ko:K03218,ko:K03437					ko00000,ko01000,ko03009,ko03016				Bacteria	1V3JP@1239,4HCF5@91061,COG0566@1,COG0566@2	NA|NA|NA	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHHNPPIF_01285	322159.STER_0295	6.1e-93	346.7	Bacilli	XK27_09705		6.1.1.14	ko:K01879,ko:K06950	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1V4QX@1239,4HHW0@91061,COG1418@1,COG1418@2	NA|NA|NA	S	HD superfamily hydrolase
NHHNPPIF_01286	322159.STER_0296	1.5e-97	362.5	Bacilli	ybhL	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K06890					ko00000				Bacteria	1V779@1239,4HIX1@91061,COG0670@1,COG0670@2	NA|NA|NA	S	Belongs to the BI1 family
NHHNPPIF_01289	264199.stu0252	1.6e-243	848.2	Bacilli	lysA		4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPE9@1239,4H9XW@91061,COG0019@1,COG0019@2	NA|NA|NA	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NHHNPPIF_01290	322159.STER_0300	2.4e-90	338.2	Bacteria													Bacteria	COG1309@1,COG1309@2	NA|NA|NA	K	transcriptional regulator
NHHNPPIF_01291	264199.stu0254	7.6e-36	156.0	Bacilli	yneF			ko:K09976					ko00000				Bacteria	1VDSU@1239,4HM8G@91061,COG3763@1,COG3763@2	NA|NA|NA	S	UPF0154 protein
NHHNPPIF_01292	322159.STER_0302	4.2e-147	527.3	Bacilli	murI	GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0042802,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100		R00260	RC00302	ko00000,ko00001,ko01000,ko01011			iYO844.BSU28390	Bacteria	1TPPR@1239,4HA46@91061,COG0796@1,COG0796@2	NA|NA|NA	M	Provides the (R)-glutamate required for cell wall biosynthesis
NHHNPPIF_01293	264199.stu0256	7.1e-186	656.4	Bacilli	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66,5.1.1.3	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100		R00260,R00426,R00720,R01855,R02100,R02720,R03531	RC00002,RC00302	ko00000,ko00001,ko01000,ko01011				Bacteria	1V6RN@1239,4HCP6@91061,COG0127@1,COG0127@2	NA|NA|NA	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NHHNPPIF_01294	264199.stu0257	3.5e-99	367.5	Bacilli	XK27_09740			ko:K07095					ko00000				Bacteria	1VA0U@1239,4HM24@91061,COG0622@1,COG0622@2	NA|NA|NA	S	Phosphoesterase
NHHNPPIF_01295	322159.STER_0305	7.8e-85	319.7	Bacilli	ykuL												Bacteria	1VFAB@1239,4HRWJ@91061,COG0517@1,COG0517@2	NA|NA|NA	S	CBS domain
NHHNPPIF_01296	264199.stu0259	2.8e-137	494.6	Bacilli	xerD			ko:K04763					ko00000,ko03036				Bacteria	1VY7C@1239,4IT0W@91061,COG4974@1,COG4974@2	NA|NA|NA	L	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
NHHNPPIF_01297	264199.stu0260	1.5e-121	442.2	Bacilli	scpA	GO:0003674,GO:0005488,GO:0005515,GO:0042802		ko:K05896					ko00000,ko03036				Bacteria	1V8JV@1239,4IQZ5@91061,COG1354@1,COG1354@2	NA|NA|NA	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NHHNPPIF_01298	264199.stu0261	3e-99	367.9	Bacilli	scpB	GO:0003674,GO:0005488,GO:0005515,GO:0042802		ko:K06024					ko00000,ko03036				Bacteria	1V6HI@1239,4HIQ0@91061,COG1386@1,COG1386@2	NA|NA|NA	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NHHNPPIF_01299	264199.stu0262	1.6e-140	505.4	Bacilli	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.21,5.4.99.22	ko:K06178,ko:K06182,ko:K06183					ko00000,ko01000,ko03009				Bacteria	1TP68@1239,4H9MU@91061,COG1187@1,COG1187@2	NA|NA|NA	J	Belongs to the pseudouridine synthase RsuA family
NHHNPPIF_01300	264199.stu0263	4e-40	170.2	Bacilli	yidD			ko:K08998					ko00000				Bacteria	1VEIG@1239,4HPA3@91061,COG0759@1,COG0759@2	NA|NA|NA	S	Could be involved in insertion of integral membrane proteins into the membrane
NHHNPPIF_01301	264199.stu0264	4.8e-255	886.7	Bacilli	trkH	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031224,GO:0031226,GO:0031420,GO:0034220,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662		ko:K03498,ko:K03499					ko00000,ko02000	2.A.38.1,2.A.38.4		iECDH1ME8569_1439.ECDH1ME8569_1308,iPC815.YPO3762,iSFV_1184.SFV_3651	Bacteria	1TPAF@1239,4HCWN@91061,COG0168@1,COG0168@2	NA|NA|NA	P	Cation transport protein
NHHNPPIF_01302	264199.stu0265	1.4e-245	855.1	Bacilli	trkA			ko:K03499					ko00000,ko02000	2.A.38.1,2.A.38.4			Bacteria	1TPNS@1239,4HCRM@91061,COG0569@1,COG0569@2	NA|NA|NA	P	Potassium transporter peripheral membrane component
NHHNPPIF_01303	264199.stu0267	1.6e-96	358.6	Bacilli	trmL	GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.207	ko:K03216					ko00000,ko01000,ko03016				Bacteria	1V3GW@1239,4HFNY@91061,COG0219@1,COG0219@2	NA|NA|NA	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NHHNPPIF_01304	264199.stu0268	5.5e-90	337.0	Bacilli	ribU	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656											Bacteria	1V4BW@1239,4HHFT@91061,COG3601@1,COG3601@2	NA|NA|NA	U	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NHHNPPIF_01305	264199.stu0269	1.1e-110	406.0	Bacilli	bcrC		3.6.1.27	ko:K19302	ko00550,map00550		R05627	RC00002	ko00000,ko00001,ko01000,ko01011				Bacteria	1VF2U@1239,4HNXR@91061,COG0671@1,COG0671@2	NA|NA|NA	I	Membrane-associated phospholipid phosphatase
NHHNPPIF_01306	264199.stu0270	1.2e-160	572.4	Bacteria				ko:K20342,ko:K20480	ko02024,map02024				ko00000,ko00001,ko03000				Bacteria	COG1396@1,COG1396@2	NA|NA|NA	K	sequence-specific DNA binding
NHHNPPIF_01307	264199.stu0271	1.9e-33	147.9	Bacteria		GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702		ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024				ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.21			Bacteria	COG2274@1,COG2274@2	NA|NA|NA	V	protein secretion by the type I secretion system
NHHNPPIF_01308	264199.stu0272	5.5e-105	387.1	Bacilli		GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702		ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024				ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.21			Bacteria	1V77J@1239,4HAX2@91061,COG2274@1,COG2274@2	NA|NA|NA	V	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NHHNPPIF_01309	1046629.Ssal_01906	3.2e-75	287.7	Bacilli	comA			ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024				ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.21			Bacteria	1V77J@1239,4HAX2@91061,COG2274@1,COG2274@2	NA|NA|NA	V	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NHHNPPIF_01310	904306.HMPREF9192_0124	2.4e-85	321.6	Bacilli	comA			ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024				ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.21			Bacteria	1V77J@1239,4HAX2@91061,COG2274@1,COG2274@2	NA|NA|NA	V	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NHHNPPIF_01311	1046629.Ssal_01905	2.1e-30	138.3	Bacteria	yhaI												Bacteria	COG3152@1,COG3152@2	NA|NA|NA	L	Membrane
NHHNPPIF_01312	1046629.Ssal_01904	1.5e-56	225.3	Firmicutes													Bacteria	1VCM1@1239,2E26M@1,32XD2@2	NA|NA|NA	S	Domain of unknown function (DUF4173)
NHHNPPIF_01313	264199.stu0280	3.4e-94	350.9	Firmicutes	ureI	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K03191,ko:K22112	ko05120,map05120				ko00000,ko00001,ko02000	1.A.29.1.1,1.A.29.1.2,1.A.29.1.3,1.A.29.1.4,1.A.29.1.5,1.A.29.1.6			Bacteria	1VAKB@1239,29DTM@1,300RH@2	NA|NA|NA	S	AmiS/UreI family transporter
NHHNPPIF_01314	264199.stu0281	7.6e-46	189.5	Bacilli	ureA	GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0019627,GO:0034641,GO:0042221,GO:0043419,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071704,GO:0071941,GO:1901564,GO:1901565,GO:1901575	3.5.1.5	ko:K01430,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120		R00131	RC02798,RC02806	ko00000,ko00001,ko01000			iYO844.BSU36660	Bacteria	1V7GU@1239,4HIJS@91061,COG0831@1,COG0831@2	NA|NA|NA	E	Belongs to the urease gamma subunit family
NHHNPPIF_01315	1046629.Ssal_01901	1.7e-53	214.9	Bacilli	ureB	GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0019627,GO:0034641,GO:0042221,GO:0043419,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071704,GO:0071941,GO:1901564,GO:1901565,GO:1901575	3.5.1.5	ko:K01429,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120		R00131	RC02798,RC02806	ko00000,ko00001,ko01000				Bacteria	1VAIA@1239,4HM0I@91061,COG0832@1,COG0832@2	NA|NA|NA	E	Belongs to the urease beta subunit family
NHHNPPIF_01316	904306.HMPREF9192_0116	0.0	1154.4	Bacilli	ureC		3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120		R00131	RC02798,RC02806	ko00000,ko00001,ko01000				Bacteria	1TPQP@1239,4HBTS@91061,COG0804@1,COG0804@2	NA|NA|NA	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NHHNPPIF_01317	1046629.Ssal_01898	6.6e-78	296.6	Bacteria	ureE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464		ko:K03187					ko00000				Bacteria	COG2371@1,COG2371@2	NA|NA|NA	O	enzyme active site formation
NHHNPPIF_01318	264199.stu0285	5.3e-130	470.3	Bacilli	ureF			ko:K03188					ko00000				Bacteria	1V2H0@1239,4HKQE@91061,COG0830@1,COG0830@2	NA|NA|NA	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NHHNPPIF_01319	1046629.Ssal_01896	9.5e-112	409.5	Bacilli	ureG			ko:K03189,ko:K04652					ko00000,ko03110				Bacteria	1TS00@1239,4HC5C@91061,COG0378@1,COG0378@2	NA|NA|NA	KO	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NHHNPPIF_01320	264199.stu0287	8.9e-161	572.8	Bacilli	ureD			ko:K03190					ko00000				Bacteria	1TVM2@1239,4HCED@91061,COG0829@1,COG0829@2	NA|NA|NA	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NHHNPPIF_01321	322159.STER_0330	3.9e-176	624.0	Bacilli	cbiM	GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351		ko:K02007	ko02010,map02010	M00245,M00246			ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23			Bacteria	1TPEN@1239,4HARY@91061,COG0310@1,COG0310@2	NA|NA|NA	P	PDGLE domain
NHHNPPIF_01322	264199.stu0289	2.3e-134	485.0	Firmicutes				ko:K02008	ko02010,map02010	M00245,M00246			ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23			Bacteria	1V7YC@1239,COG0619@1,COG0619@2	NA|NA|NA	P	cobalt transport protein
NHHNPPIF_01323	264199.stu0290	3.1e-130	471.1	Bacilli	cbiO	GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351		ko:K02006	ko02010,map02010	M00245,M00246			ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23			Bacteria	1V16T@1239,4HI15@91061,COG1122@1,COG1122@2	NA|NA|NA	P	ABC transporter
NHHNPPIF_01324	264199.stu1196	8.2e-274	949.1	Bacilli	pyk	GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009986,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0022607,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065	2.7.1.40,2.7.7.4	ko:K00873,ko:K00958	ko00010,ko00230,ko00261,ko00450,ko00620,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00261,map00450,map00620,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050,M00176,M00596	R00200,R00430,R00529,R01138,R01858,R02320,R04929	RC00002,RC00015,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147			iECO103_1326.ECO103_1819,iPC815.YPO2393	Bacteria	1TPGG@1239,4H9VY@91061,COG0469@1,COG0469@2	NA|NA|NA	G	Belongs to the pyruvate kinase family
NHHNPPIF_01325	264199.stu1197	2.1e-188	664.8	Bacilli	pfkA	GO:0003674,GO:0003824,GO:0003872,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061615,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019			iYO844.BSU29190	Bacteria	1TPF4@1239,4HAPN@91061,COG0205@1,COG0205@2	NA|NA|NA	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NHHNPPIF_01326	322159.STER_1165	0.0	2029.2	Bacilli	dnaE		2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1TPYG@1239,4H9T3@91061,COG0587@1,COG0587@2	NA|NA|NA	L	DNA polymerase
NHHNPPIF_01327	264199.stu1199	1.4e-152	545.4	Bacilli	sua5		2.7.7.87	ko:K07566			R10463	RC00745	ko00000,ko01000,ko03009,ko03016				Bacteria	1U3HQ@1239,4HFGZ@91061,COG0009@1,COG0009@2	NA|NA|NA	J	Belongs to the SUA5 family
NHHNPPIF_01328	264199.stu1200	3.1e-112	411.0	Bacilli	leuD		4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	1V1I6@1239,4HFTY@91061,COG0066@1,COG0066@2	NA|NA|NA	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NHHNPPIF_01329	322159.STER_1168	6.8e-275	952.6	Bacilli	leuC	GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000			iEcE24377_1341.EcE24377A_0075,iPC815.YPO0531,iSB619.SA_RS10700	Bacteria	1TPE5@1239,4HAWA@91061,COG0065@1,COG0065@2	NA|NA|NA	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NHHNPPIF_01330	322159.STER_1169	2.5e-43	181.0	Bacteria	ysdA												Bacteria	COG3326@1,COG3326@2	NA|NA|NA	L	Membrane
NHHNPPIF_01331	264199.stu1202	6.6e-190	669.8	Bacilli	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000				Bacteria	1TPEM@1239,4HATP@91061,COG0473@1,COG0473@2	NA|NA|NA	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NHHNPPIF_01332	322159.STER_1171	5.9e-291	1006.1	Bacilli	leuA		2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000			iSB619.SA_RS10690,iYO844.BSU28280	Bacteria	1TP4Y@1239,4HA6E@91061,COG0119@1,COG0119@2	NA|NA|NA	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NHHNPPIF_01333	264199.stu1204	4.6e-131	473.8	Bacilli	gpmA	GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147				Bacteria	1TQFP@1239,4HAW7@91061,COG0588@1,COG0588@2	NA|NA|NA	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NHHNPPIF_01334	322159.STER_1173	2.5e-180	637.9	Bacilli	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.98.1	ko:K00226,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01867,R01869	RC00051	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPFV@1239,4HBFE@91061,COG0167@1,COG0167@2	NA|NA|NA	F	Catalyzes the conversion of dihydroorotate to orotate
NHHNPPIF_01336	264199.stu1209	2.8e-39	167.5	Bacilli	hup			ko:K03530					ko00000,ko03032,ko03036,ko03400				Bacteria	1V9XQ@1239,4HKF2@91061,COG0776@1,COG0776@2	NA|NA|NA	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NHHNPPIF_01337	264199.stu1210	1.7e-94	352.1	Bacilli	ypmS												Bacteria	1VF0K@1239,4HIYN@91061,COG4698@1,COG4698@2	NA|NA|NA	S	Protein conserved in bacteria
NHHNPPIF_01338	264199.stu1211	6.7e-87	326.6	Bacteria	ypmR	GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0016298,GO:0016787,GO:0016788,GO:0052689											Bacteria	COG2755@1,COG2755@2	NA|NA|NA	E	lipolytic protein G-D-S-L family
NHHNPPIF_01339	1046629.Ssal_01285	3.8e-45	187.6	Bacilli	ypmR	GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0016298,GO:0016787,GO:0016788,GO:0052689											Bacteria	1V1HR@1239,4HDXS@91061,COG2755@1,COG2755@2	NA|NA|NA	E	COG2755 Lysophospholipase L1 and related esterases
NHHNPPIF_01340	264199.stu1212	3.3e-147	527.7	Bacilli	DegV												Bacteria	1TRZ4@1239,4HBR8@91061,COG1307@1,COG1307@2	NA|NA|NA	S	DegV family
NHHNPPIF_01341	322159.STER_1179	2.9e-304	1050.4	Bacilli	recN	GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360		ko:K03631,ko:K13582	ko04112,map04112				ko00000,ko00001,ko03400				Bacteria	1TP99@1239,4H9ZR@91061,COG0497@1,COG0497@2	NA|NA|NA	L	May be involved in recombinational repair of damaged DNA
NHHNPPIF_01342	322159.STER_1180	3.7e-73	280.8	Bacilli	argR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141		ko:K03402					ko00000,ko03000				Bacteria	1V1R7@1239,4HFY8@91061,COG1438@1,COG1438@2	NA|NA|NA	K	Regulates arginine biosynthesis genes
NHHNPPIF_01343	264199.stu1215	4.7e-157	560.5	Bacilli	rrmJ		2.1.1.226,2.1.1.227	ko:K06442					ko00000,ko01000,ko03009				Bacteria	1TPE4@1239,4HAPY@91061,COG1189@1,COG1189@2	NA|NA|NA	J	Ribosomal RNA large subunit methyltransferase J
NHHNPPIF_01344	264199.stu1216	6.6e-159	566.6	Bacilli	ispA	GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0071704,GO:1901576	2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90	ko:K00795,ko:K02523,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061,R09248	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006				Bacteria	1TPQY@1239,4HA8E@91061,COG0142@1,COG0142@2	NA|NA|NA	H	Belongs to the FPP GGPP synthase family
NHHNPPIF_01345	264199.stu1217	3.5e-29	133.7	Bacteria	xseB		3.1.11.6	ko:K03602	ko03430,map03430				ko00000,ko00001,ko01000,ko03400				Bacteria	COG1722@1,COG1722@2	NA|NA|NA	L	exodeoxyribonuclease VII activity
NHHNPPIF_01346	264199.stu1218	2.6e-247	860.9	Bacilli	xseA		3.1.11.6	ko:K03601	ko03430,map03430				ko00000,ko00001,ko01000,ko03400				Bacteria	1TP4E@1239,4HAN2@91061,COG1570@1,COG1570@2	NA|NA|NA	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHHNPPIF_01347	1198676.SMUGS5_04945	2.5e-07	62.4	Bacteria													Bacteria	COG4640@1,COG4640@2	NA|NA|NA	KT	response to antibiotic
NHHNPPIF_01349	264199.stu1220	3.4e-120	437.6	Bacilli	nth		4.2.99.18	ko:K10773	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	1TRAK@1239,4HATD@91061,COG0177@1,COG0177@2	NA|NA|NA	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NHHNPPIF_01350	264199.stu1221	1.5e-124	452.2	Bacteria	dnaD			ko:K02086					ko00000				Bacteria	COG3935@1,COG3935@2	NA|NA|NA		
NHHNPPIF_01351	322159.STER_1189	1.3e-181	642.1	Bacilli	metA	GO:0003674,GO:0003824,GO:0008374,GO:0008899,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQVR@1239,4H9W4@91061,COG1897@1,COG1897@2	NA|NA|NA	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NHHNPPIF_01352	264199.stu1223	2e-94	351.7	Bacilli	apt	GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.22,2.4.2.7	ko:K00759,ko:K03816,ko:K09685	ko00230,ko01100,ko01110,map00230,map01100,map01110		R00190,R01229,R02142,R04378	RC00063,RC00122	ko00000,ko00001,ko01000,ko03000,ko04147				Bacteria	1V1BV@1239,4HFUA@91061,COG0503@1,COG0503@2	NA|NA|NA	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NHHNPPIF_01353	322159.STER_1191	0.0	1439.5	Bacilli	recJ			ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1TPXE@1239,4H9UP@91061,COG0608@1,COG0608@2,COG4199@1,COG4199@2	NA|NA|NA	L	Single-strand DNA-specific exonuclease, C terminal domain
NHHNPPIF_01354	322159.STER_1192	1.5e-138	498.8	Bacilli	XK27_05435		1.1.1.100	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	1TSJ3@1239,4HDU5@91061,COG0300@1,COG0300@2	NA|NA|NA	S	Belongs to the short-chain dehydrogenases reductases (SDR) family
NHHNPPIF_01355	264199.stu1226	9.2e-175	619.4	Bacilli	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016891,GO:0016893,GO:0016896,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013				ko00000,ko00001,ko01000,ko03016				Bacteria	1TRGP@1239,4HABM@91061,COG1234@1,COG1234@2	NA|NA|NA	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NHHNPPIF_01356	264199.stu1227	3.9e-116	424.1	Bacilli	galT		2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000				Bacteria	1VY8D@1239,4HXPD@91061,COG4468@1,COG4468@2	NA|NA|NA	G	UDPglucose--hexose-1-phosphate uridylyltransferase
NHHNPPIF_01357	264199.stu1228	2.7e-222	777.7	Bacilli	hflX	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877		ko:K03665					ko00000,ko03009				Bacteria	1TNZB@1239,4HACA@91061,COG2262@1,COG2262@2	NA|NA|NA	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NHHNPPIF_01358	322159.STER_1197	7.3e-232	809.7	Bacilli	rodA			ko:K05837					ko00000,ko03036				Bacteria	1TPGH@1239,4HAV4@91061,COG0772@1,COG0772@2	NA|NA|NA	D	Belongs to the SEDS family
NHHNPPIF_01359	1046629.Ssal_01315	2e-49	201.4	Bacteria	hisE	GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.4.19,3.6.1.31,5.3.1.16	ko:K01523,ko:K01814,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037,R04640	RC00002,RC00945,RC01055	ko00000,ko00001,ko00002,ko01000			iSB619.SA_RS14110,iYO844.BSU34860	Bacteria	COG0140@1,COG0140@2	NA|NA|NA	E	phosphoribosyl-ATP diphosphatase activity
NHHNPPIF_01360	322159.STER_1199	8e-60	236.1	Bacilli	hisI	GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.4.19,3.5.4.25,3.6.1.31,5.3.1.16	ko:K01496,ko:K01497,ko:K01814,ko:K11755	ko00340,ko00740,ko00790,ko01100,ko01110,ko01230,ko02024,map00340,map00740,map00790,map01100,map01110,map01230,map02024	M00026,M00125	R00425,R04035,R04037,R04640	RC00002,RC00293,RC00945,RC01055,RC02504	ko00000,ko00001,ko00002,ko01000			iECNA114_1301.ECNA114_0880,iECW_1372.ECW_m2186,iEKO11_1354.EKO11_1768,iHN637.CLJU_RS05760,iSB619.SA_RS14110,iUMN146_1321.UM146_06665,iWFL_1372.ECW_m2186	Bacteria	1UYNA@1239,4HA9R@91061,COG0139@1,COG0139@2	NA|NA|NA	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NHHNPPIF_01361	322159.STER_1200	8.9e-136	489.6	Bacilli	hisF	GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	3.5.4.19,3.6.1.31	ko:K01663,ko:K02500,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037,R04558	RC00002,RC00010,RC01055,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000			iECO111_1330.ECO111_2749,iEcolC_1368.EcolC_1617,iHN637.CLJU_RS05755,iLJ478.TM1036,iSB619.SA_RS14115,iYL1228.KPN_02481	Bacteria	1TP0W@1239,4HAAM@91061,COG0107@1,COG0107@2	NA|NA|NA	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NHHNPPIF_01362	322159.STER_1201	1.9e-127	461.8	Bacilli	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_0388	Bacteria	1V1IR@1239,4HACP@91061,COG0106@1,COG0106@2	NA|NA|NA	E	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NHHNPPIF_01363	322159.STER_1202	9.8e-109	399.4	Bacilli	hisH			ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQT0@1239,4HHNQ@91061,COG0118@1,COG0118@2	NA|NA|NA	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NHHNPPIF_01364	322159.STER_1203	1.5e-106	392.1	Bacilli	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23,2.6.1.9,3.1.3.15,4.2.1.19	ko:K00013,ko:K00817,ko:K01089,ko:K01693	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R01158,R01163,R03012,R03013,R03243,R03457	RC00006,RC00017,RC00099,RC00242,RC00463,RC00888,RC00932	ko00000,ko00001,ko00002,ko01000,ko01007			iECO111_1330.ECO111_2746,iECS88_1305.ECS88_2121,iJN746.PP_0289,iLJ478.TM1039,iSB619.SA_RS14130,iUMNK88_1353.UMNK88_2570	Bacteria	1TRH7@1239,4HCFG@91061,COG0131@1,COG0131@2	NA|NA|NA	E	imidazoleglycerol-phosphate dehydratase
NHHNPPIF_01365	322159.STER_1204	7.8e-233	812.8	Bacilli	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23,1.1.1.308	ko:K00013,ko:K15509	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPAW@1239,4H9XK@91061,COG0141@1,COG0141@2	NA|NA|NA	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NHHNPPIF_01366	322159.STER_1205	4e-116	424.1	Bacilli	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000				Bacteria	1TSVZ@1239,4H9MH@91061,COG0040@1,COG0040@2	NA|NA|NA	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NHHNPPIF_01367	322159.STER_1206	5.7e-183	646.7	Bacilli	hisZ		2.4.2.17,6.1.1.21	ko:K00765,ko:K01892,ko:K02502	ko00340,ko00970,ko01100,ko01110,ko01230,map00340,map00970,map01100,map01110,map01230	M00026,M00359,M00360	R01071,R03655	RC00055,RC00523,RC02819,RC03200	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1TPZZ@1239,4HBBA@91061,COG3705@1,COG3705@2	NA|NA|NA	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NHHNPPIF_01368	322159.STER_1207	8.2e-196	689.5	Bacilli	hisC		2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007			iJN678.hisC	Bacteria	1TPUV@1239,4HA1H@91061,COG0079@1,COG0079@2	NA|NA|NA	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NHHNPPIF_01370	1161413.HMPREF1510_1836	1.3e-31	141.7	Firmicutes				ko:K07497					ko00000				Bacteria	1TQQY@1239,COG2801@1,COG2801@2	NA|NA|NA	L	Integrase core domain protein
NHHNPPIF_01371	1123299.AUKZ01000011_gene1075	1e-69	269.2	Bacilli	doc			ko:K07341					ko00000,ko02048				Bacteria	1VCC8@1239,4HKXW@91061,COG3654@1,COG3654@2	NA|NA|NA	S	Prophage maintenance system killer protein
NHHNPPIF_01372	1321372.AQQB01000076_gene537	3.3e-30	137.1	Streptococcus suis													Bacteria	1U996@1239,1WU2Q@1307,2B3ZK@1,31WPQ@2,4IJBS@91061	NA|NA|NA	S	Antidote-toxin recognition MazE, bacterial antitoxin
NHHNPPIF_01373	264199.stu1386	8.5e-09	66.2	Bacilli													Bacteria	1VBXK@1239,2CWIF@1,32SZQ@2,4HWJ5@91061	NA|NA|NA		
NHHNPPIF_01374	1403946.Q615_SPAC00123G0004	3.1e-44	184.1	Bacilli				ko:K07483					ko00000				Bacteria	1V9ZX@1239,4HKN9@91061,COG2963@1,COG2963@2	NA|NA|NA	L	COG2963 Transposase and inactivated derivatives
NHHNPPIF_01375	1403946.Q615_SPAC00123G0003	5.9e-62	243.4	Bacilli													Bacteria	1TPEH@1239,4HCHG@91061,COG2801@1,COG2801@2	NA|NA|NA	L	Transposase and inactivated derivatives
NHHNPPIF_01376	1123299.AUKZ01000032_gene1329	1.5e-39	168.3	Bacteria													Bacteria	COG2801@1,COG2801@2	NA|NA|NA	L	transposition
NHHNPPIF_01377	322159.STER_0767	4.2e-92	344.0	Bacilli	dps			ko:K04047					ko00000,ko03036				Bacteria	1VCVJ@1239,4HMBD@91061,COG0783@1,COG0783@2	NA|NA|NA	P	Belongs to the Dps family
NHHNPPIF_01378	264199.stu0722	4.4e-115	420.6	Firmicutes	pilD		3.4.23.43	ko:K02236,ko:K02506,ko:K02654		M00331,M00429			ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2			Bacteria	1V91J@1239,COG1989@1,COG1989@2	NA|NA|NA	NOU	Bacterial Peptidase A24 N-terminal domain
NHHNPPIF_01379	322159.STER_0765	6.3e-191	673.7	Bacilli			3.5.2.6	ko:K01467,ko:K17836	ko00311,ko01130,ko01501,ko02020,map00311,map01130,map01501,map02020	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504				Bacteria	1VHF8@1239,4HU1N@91061,COG2367@1,COG2367@2	NA|NA|NA	V	D-alanyl-D-alanine carboxypeptidase
NHHNPPIF_01387	904306.HMPREF9192_0691	9.5e-140	503.1	Bacilli	blpT												Bacteria	1W6SH@1239,2DWQH@1,341F6@2,4HX74@91061	NA|NA|NA		
NHHNPPIF_01388	322159.STER_1636	3e-47	194.1	Bacteria	spiA			ko:K18831					ko00000,ko02048,ko03000				Bacteria	COG1476@1,COG1476@2	NA|NA|NA	K	sequence-specific DNA binding
NHHNPPIF_01391	322159.STER_1633	0.0	1515.7	Bacilli	pepX		3.4.14.11	ko:K01281					ko00000,ko01000,ko01002				Bacteria	1TT78@1239,4HBA0@91061,COG2936@1,COG2936@2	NA|NA|NA	E	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NHHNPPIF_01392	264199.stu1671	2.3e-164	584.7	Bacilli	gla			ko:K02440					ko00000,ko02000	1.A.8.1,1.A.8.2			Bacteria	1TP4T@1239,4HE39@91061,COG0580@1,COG0580@2	NA|NA|NA	U	Belongs to the MIP aquaporin (TC 1.A.8) family
NHHNPPIF_01393	1116231.SMA_1918	1.3e-196	692.2	Bacteria			2.7.7.73,2.7.7.80	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122		R07459	RC00043	ko00000,ko00001,ko01000				Bacteria	COG0476@1,COG0476@2	NA|NA|NA	H	Involved in molybdopterin and thiamine biosynthesis, family 2
NHHNPPIF_01394	1116231.SMA_1917	2.2e-186	658.3	Bacteria	yxaM												Bacteria	COG0477@1,COG2814@2	NA|NA|NA	EGP	Major facilitator Superfamily
NHHNPPIF_01395	1046629.Ssal_00076	1.1e-89	335.9	Bacilli	adk		2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1V7AW@1239,4HH8A@91061,COG0563@1,COG0563@2	NA|NA|NA	F	topology modulation protein
NHHNPPIF_01396	322159.STER_1913	7.8e-249	865.9	Bacilli	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQ4C@1239,4H9YT@91061,COG0104@1,COG0104@2	NA|NA|NA	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NHHNPPIF_01397	1069533.Sinf_0020	2.9e-24	117.1	Firmicutes													Bacteria	1TQ93@1239,COG3464@1,COG3464@2	NA|NA|NA	L	Transposase
NHHNPPIF_01398	1046629.Ssal_00627	1.2e-24	118.2	Bacilli	oppF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1V36J@1239,4HCM4@91061,COG4608@1,COG4608@2	NA|NA|NA	P	Belongs to the ABC transporter superfamily
NHHNPPIF_01399	322159.STER_1411	0.0	1279.6	Bacilli	amiA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1TQVS@1239,4HCCB@91061,COG4166@1,COG4166@2	NA|NA|NA	E	ABC transporter, substrate-binding protein, family 5
NHHNPPIF_01400	904306.HMPREF9192_0942	1.1e-270	938.7	Bacilli	amiC	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085		ko:K02033,ko:K13894,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00349,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.21,3.A.1.5.24,3.A.1.5.25			Bacteria	1UY5U@1239,4HEZK@91061,COG0601@1,COG0601@2	NA|NA|NA	P	ABC transporter (Permease
NHHNPPIF_01401	264199.stu1440	3.1e-167	594.3	Bacilli	amiD			ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1TP4R@1239,4HE8S@91061,COG1173@1,COG1173@2	NA|NA|NA	P	ABC transporter (Permease
NHHNPPIF_01402	264199.stu1439	1.4e-203	715.3	Bacilli	oppD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1TP6E@1239,4H9MR@91061,COG0444@1,COG0444@2	NA|NA|NA	P	Belongs to the ABC transporter superfamily
NHHNPPIF_01403	264199.stu1438	5.2e-119	433.7	Bacilli	oppF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1V36J@1239,4HCM4@91061,COG4608@1,COG4608@2	NA|NA|NA	P	Belongs to the ABC transporter superfamily
NHHNPPIF_01404	322159.STER_1755	1.7e-221	775.0	Bacilli	pgk	GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147			iSB619.SA_RS04145	Bacteria	1TP3H@1239,4H9R3@91061,COG0126@1,COG0126@2	NA|NA|NA	F	Belongs to the phosphoglycerate kinase family
NHHNPPIF_01405	1046629.Ssal_00123	7.9e-41	172.6	Bacilli				ko:K07491					ko00000				Bacteria	1V1CM@1239,4HBWU@91061,COG1943@1,COG1943@2	NA|NA|NA	L	COG1943 Transposase and inactivated derivatives
NHHNPPIF_01406	322159.STER_1320	5.3e-150	537.0	Bacilli			1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPRF@1239,4HAE7@91061,COG2514@1,COG2514@2	NA|NA|NA	S	glyoxalase
NHHNPPIF_01407	264199.stu1363	5.7e-109	400.2	Bacilli	XK27_02070			ko:K07078					ko00000				Bacteria	1V1CR@1239,4HD6W@91061,COG3560@1,COG3560@2	NA|NA|NA	S	nitroreductase
NHHNPPIF_01409	435842.HMPREF0848_00939	2.1e-71	275.0	Bacilli	ydhF												Bacteria	1TQ12@1239,4HA57@91061,COG4989@1,COG4989@2	NA|NA|NA	S	Aldo keto reductase
NHHNPPIF_01410	1046629.Ssal_00802	9.4e-68	262.7	Bacilli	ydhF												Bacteria	1TQ12@1239,4HA57@91061,COG4989@1,COG4989@2	NA|NA|NA	S	Aldo keto reductase
NHHNPPIF_01411	889204.HMPREF9423_0305	3.9e-82	310.8	Bacilli													Bacteria	1V2BY@1239,4HPW3@91061,COG1309@1,COG1309@2	NA|NA|NA	K	WHG domain
NHHNPPIF_01412	1316408.HSISM1_1672	3.2e-91	341.3	Bacilli				ko:K02003		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	1U3WD@1239,4HV7M@91061,COG1136@1,COG1136@2	NA|NA|NA	V	abc transporter atp-binding protein
NHHNPPIF_01413	1095727.HMPREF1117_1383	5.9e-23	113.2	Bacilli				ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	1TSN2@1239,28K0P@1,2Z9QJ@2,4HU6K@91061	NA|NA|NA	P	FtsX-like permease family
NHHNPPIF_01414	1046629.Ssal_00807	2.4e-40	171.0	Bacilli				ko:K15383					ko00000,ko02000	9.A.58.2			Bacteria	1VBI9@1239,4HN2M@91061,COG4095@1,COG4095@2	NA|NA|NA	S	Sugar efflux transporter for intercellular exchange
NHHNPPIF_01415	435842.HMPREF0848_00934	1.1e-83	315.8	Bacilli	btuE		1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918		R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000				Bacteria	1V3M3@1239,4HH5Q@91061,COG0386@1,COG0386@2	NA|NA|NA	O	Belongs to the glutathione peroxidase family
NHHNPPIF_01416	435842.HMPREF0848_00933	4e-160	570.9	Bacilli			4.1.1.37	ko:K01599,ko:K16957	ko00860,ko01100,ko01110,ko02010,map00860,map01100,map01110,map02010	M00121,M00585	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.13			Bacteria	1TNYE@1239,4HQ5B@91061,COG0407@1,COG0407@2	NA|NA|NA	H	Uroporphyrinogen decarboxylase (URO-D)
NHHNPPIF_01417	435842.HMPREF0848_00932	2.4e-161	574.7	Bacilli				ko:K16957	ko02010,map02010	M00585			ko00000,ko00001,ko00002,ko02000	3.A.1.3.13			Bacteria	1UX4B@1239,4HG72@91061,COG0834@1,COG0834@2	NA|NA|NA	ET	ABC transporter substrate-binding protein
NHHNPPIF_01418	435842.HMPREF0848_00931	6.1e-107	393.7	Bacilli	ytmL			ko:K02029,ko:K10009,ko:K16958,ko:K16959	ko02010,map02010	M00234,M00236,M00585			ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.10,3.A.1.3.13,3.A.1.3.14			Bacteria	1V4Q3@1239,4HDVS@91061,COG0765@1,COG0765@2	NA|NA|NA	P	ABC transporter (Permease
NHHNPPIF_01419	435842.HMPREF0848_00930	6.7e-114	416.8	Bacilli	yxeN			ko:K16959,ko:K16962	ko02010,map02010	M00585,M00586			ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.13			Bacteria	1V1PT@1239,4HI18@91061,COG0765@1,COG0765@2	NA|NA|NA	P	ABC transporter, permease protein
NHHNPPIF_01420	435842.HMPREF0848_00929	6.9e-136	490.0	Bacilli	tcyC2		3.6.3.21	ko:K02028,ko:K10010,ko:K16960	ko02010,map02010	M00234,M00236,M00585			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.10,3.A.1.3.13,3.A.1.3.14			Bacteria	1TNYD@1239,4H9WY@91061,COG1126@1,COG1126@2	NA|NA|NA	E	abc transporter atp-binding protein
NHHNPPIF_01423	1161413.HMPREF1510_1836	1.6e-21	107.8	Firmicutes				ko:K07497					ko00000				Bacteria	1TQQY@1239,COG2801@1,COG2801@2	NA|NA|NA	L	Integrase core domain protein
NHHNPPIF_01424	435842.HMPREF0848_00928	1.1e-139	502.7	Bacteria													Bacteria	COG5263@1,COG5263@2	NA|NA|NA	S	dextransucrase activity
NHHNPPIF_01425	435842.HMPREF0848_00928	8.8e-39	166.0	Bacteria													Bacteria	COG5263@1,COG5263@2	NA|NA|NA	S	dextransucrase activity
NHHNPPIF_01426	435842.HMPREF0848_00928	6.3e-14	82.8	Bacteria													Bacteria	COG5263@1,COG5263@2	NA|NA|NA	S	dextransucrase activity
NHHNPPIF_01427	1046629.Ssal_00817	4e-69	267.7	Bacteria													Bacteria	COG5263@1,COG5263@2	NA|NA|NA	S	dextransucrase activity
NHHNPPIF_01428	264199.stu1361	1.1e-227	795.8	Bacilli	yfnA			ko:K03294					ko00000	2.A.3.2			Bacteria	1TQ4K@1239,4HA66@91061,COG0531@1,COG0531@2	NA|NA|NA	E	amino acid
NHHNPPIF_01430	264199.stu1360	4.8e-25	119.8	Bacteria	csbD												Bacteria	COG3237@1,COG3237@2	NA|NA|NA	K	CsbD-like
NHHNPPIF_01431	264199.stu1359	8.2e-57	226.1	Bacilli	manA		5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000				Bacteria	1VRGI@1239,4HBFW@91061,COG1482@1,COG1482@2	NA|NA|NA	G	mannose-6-phosphate isomerase
NHHNPPIF_01432	264199.stu1358	9.4e-65	252.7	Bacilli	manA		5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000				Bacteria	1VRGI@1239,4HBFW@91061,COG1482@1,COG1482@2	NA|NA|NA	G	mannose-6-phosphate isomerase
NHHNPPIF_01433	322159.STER_1315	1.5e-234	818.5	Bacilli	brnQ	GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903785,GO:1903825,GO:1905039		ko:K03311					ko00000	2.A.26			Bacteria	1TQIS@1239,4HAKA@91061,COG1114@1,COG1114@2	NA|NA|NA	E	Component of the transport system for branched-chain amino acids
NHHNPPIF_01434	1123298.KB904062_gene865	2.3e-183	648.3	Bacilli	hipO			ko:K01436,ko:K21613					ko00000,ko01000,ko01002				Bacteria	1TPD7@1239,4H9WQ@91061,COG1473@1,COG1473@2	NA|NA|NA	E	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NHHNPPIF_01435	1154860.SAG0136_00780	3.2e-07	60.5	Bacilli	gldA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0042802,GO:0047545,GO:0055114	1.1.1.1,1.1.1.6	ko:K00001,ko:K00005,ko:K08317	ko00010,ko00071,ko00350,ko00561,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00561,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220		R00623,R00754,R01034,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10715,R10717	RC00029,RC00050,RC00087,RC00088,RC00099,RC00116,RC00117,RC00649,RC00670,RC01734,RC02273	ko00000,ko00001,ko01000			iJN678.gldA	Bacteria	1TQFU@1239,4HC8K@91061,COG0371@1,COG0371@2	NA|NA|NA	C	glycerol dehydrogenase
NHHNPPIF_01436	1123298.KB904062_gene864	5.7e-102	377.5	Bacilli	gldA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0042802,GO:0047545,GO:0055114	1.1.1.1,1.1.1.6	ko:K00001,ko:K00005,ko:K08317	ko00010,ko00071,ko00350,ko00561,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00561,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220		R00623,R00754,R01034,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10715,R10717	RC00029,RC00050,RC00087,RC00088,RC00099,RC00116,RC00117,RC00649,RC00670,RC01734,RC02273	ko00000,ko00001,ko01000			iJN678.gldA	Bacteria	1TQFU@1239,4HC8K@91061,COG0371@1,COG0371@2	NA|NA|NA	C	glycerol dehydrogenase
NHHNPPIF_01437	1123298.KB904062_gene863	6e-147	527.3	Bacilli	ykrV3		2.6.1.83	ko:K08969,ko:K10206	ko00270,ko00300,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map01100,map01110,map01130,map01230	M00034,M00527	R07396,R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	1TQD6@1239,4HAHQ@91061,COG0436@1,COG0436@2	NA|NA|NA	E	mutations do not affect methionine salvage in vivo however
NHHNPPIF_01438	1123298.KB904062_gene862	2.3e-115	422.5	Bacilli	yxeQ	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0047547,GO:0071704											Bacteria	1TSD7@1239,4IS19@91061,COG2079@1,COG2079@2	NA|NA|NA	S	MmgE/PrpD family
NHHNPPIF_01439	1123298.KB904062_gene861	5.4e-58	230.7	Bacilli	yxeL			ko:K00680					ko00000,ko01000				Bacteria	1VC6Z@1239,4ISI0@91061,COG0454@1,COG0456@2	NA|NA|NA	K	Acetyltransferase (GNAT) domain
NHHNPPIF_01440	1423806.JCM15457_2516	1.4e-63	249.6	Lactobacillaceae	yxeN	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039		ko:K16961,ko:K16962	ko02010,map02010	M00586			ko00000,ko00001,ko00002,ko02000	3.A.1.3			Bacteria	1UZ2C@1239,3F7IY@33958,4HF77@91061,COG0765@1,COG0765@2	NA|NA|NA	U	ABC transporter, permease protein
NHHNPPIF_01441	1123298.KB904062_gene859	2.8e-92	345.1	Bacilli	yxeO		3.6.3.21	ko:K02028,ko:K10008,ko:K16960,ko:K16963	ko02010,map02010	M00233,M00236,M00585,M00586			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.13,3.A.1.3.9			Bacteria	1TNYD@1239,4H9WY@91061,COG1126@1,COG1126@2	NA|NA|NA	E	abc transporter atp-binding protein
NHHNPPIF_01442	1123298.KB904062_gene858	1.1e-197	696.0	Bacilli	pcaB		4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPMM@1239,4HDVU@91061,COG0015@1,COG0015@2	NA|NA|NA	F	Adenylosuccinate lyase
NHHNPPIF_01443	1123298.KB904062_gene857	2.6e-85	322.0	Bacilli	yxeM			ko:K16961	ko02010,map02010	M00586			ko00000,ko00001,ko00002,ko02000	3.A.1.3			Bacteria	1TR13@1239,4HDQ8@91061,COG0834@1,COG0834@2	NA|NA|NA	ET	Belongs to the bacterial solute-binding protein 3 family
NHHNPPIF_01444	264199.stu1343	9.7e-188	662.5	Bacilli	msrA		1.8.4.11,1.8.4.12	ko:K07304,ko:K07305,ko:K12267					ko00000,ko01000				Bacteria	1TQ3E@1239,4HAIV@91061,COG0225@1,COG0225@2,COG0229@1,COG0229@2	NA|NA|NA	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NHHNPPIF_01445	322159.STER_1313	4.5e-247	860.1	Bacilli	norM	GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085		ko:K03327					ko00000,ko02000	2.A.66.1			Bacteria	1TP5U@1239,4HA4W@91061,COG0534@1,COG0534@2	NA|NA|NA	V	Multidrug efflux pump
NHHNPPIF_01446	264199.stu1340	4.4e-59	233.8	Bacilli	pbuX	GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823		ko:K02824,ko:K03458,ko:K16169,ko:K16170					ko00000,ko02000	2.A.40,2.A.40.1.1,2.A.40.1.2,2.A.40.3.1,2.A.40.3.2		iSB619.SA_RS02140	Bacteria	1TNZZ@1239,4HBAM@91061,COG2233@1,COG2233@2	NA|NA|NA	F	xanthine permease
NHHNPPIF_01447	435842.HMPREF0848_00913	8.4e-141	506.5	Bacilli	pbuX	GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823		ko:K03458,ko:K16169,ko:K16170					ko00000,ko02000	2.A.40,2.A.40.3.1,2.A.40.3.2		iSB619.SA_RS02140	Bacteria	1TNZZ@1239,4HBAM@91061,COG2233@1,COG2233@2	NA|NA|NA	F	xanthine permease
NHHNPPIF_01448	904306.HMPREF9192_1089	5.4e-78	297.0	Bacilli	xpt	GO:0003674,GO:0003824,GO:0006139,GO:0006166,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046128,GO:0046129,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.22,2.4.2.7	ko:K00759,ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110		R00190,R01229,R02142,R04378	RC00063,RC00122	ko00000,ko00001,ko01000,ko04147			iYO844.BSU22070	Bacteria	1V1DU@1239,4HFNW@91061,COG0503@1,COG0503@2	NA|NA|NA	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NHHNPPIF_01449	1046629.Ssal_00835	4.6e-123	447.2	Bacilli													Bacteria	1TR32@1239,4HAUJ@91061,COG0745@1,COG0745@2	NA|NA|NA	KT	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHHNPPIF_01450	264199.stu1335	3.1e-165	587.8	Bacilli													Bacteria	1TQSG@1239,4HG2J@91061,COG0642@1,COG0642@2	NA|NA|NA	T	Histidine kinase
NHHNPPIF_01451	435842.HMPREF0848_00909	2.4e-133	481.5	Bacilli	macB2			ko:K02003		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	1TNZG@1239,4H9UT@91061,COG1136@1,COG1136@2	NA|NA|NA	V	ABC transporter, ATP-binding protein
NHHNPPIF_01452	264199.stu1333	0.0	1118.2	Bacilli				ko:K02004,ko:K19084	ko02010,ko02020,map02010,map02020	M00258,M00731,M00737			ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.134			Bacteria	1TR2D@1239,4H9SH@91061,COG0577@1,COG0577@2	NA|NA|NA	V	ABC transporter (permease)
NHHNPPIF_01453	264199.stu1332	2.6e-35	154.1	Bacteria	XK27_05000			ko:K06940					ko00000				Bacteria	COG0727@1,COG0727@2	NA|NA|NA	S	metal cluster binding
NHHNPPIF_01454	904306.HMPREF9192_1096	1.4e-83	315.5	Bacilli	cdd	GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006216,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009112,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009972,GO:0009987,GO:0016020,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019856,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042455,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046108,GO:0046109,GO:0046112,GO:0046131,GO:0046132,GO:0046133,GO:0046134,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047844,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0072529,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659	2.4.2.4,3.5.4.5	ko:K00758,ko:K01489	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219		R01570,R01878,R02484,R02485,R08221,R08222,R08230	RC00063,RC00074,RC00514	ko00000,ko00001,ko01000				Bacteria	1V58S@1239,4HHTM@91061,COG0295@1,COG0295@2	NA|NA|NA	F	cytidine deaminase activity
NHHNPPIF_01455	264199.stu1330	2.5e-164	584.7	Bacilli	yocS			ko:K03453					ko00000	2.A.28			Bacteria	1TP85@1239,4HBG6@91061,COG0385@1,COG0385@2	NA|NA|NA	S	Transporter
NHHNPPIF_01458	435842.HMPREF0848_00891	2.2e-157	561.6	Bacilli	XK27_09825			ko:K01990		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1UZ04@1239,4HDGQ@91061,COG1131@1,COG1131@2	NA|NA|NA	V	abc transporter atp-binding protein
NHHNPPIF_01459	322159.STER_1292	1.1e-130	472.6	Firmicutes	yvfS			ko:K01992		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1V1AU@1239,COG0842@1,COG0842@2	NA|NA|NA	V	ABC-2 type transporter
NHHNPPIF_01460	322159.STER_1291	4.5e-189	667.2	Bacilli	desK	GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	2.7.13.3	ko:K07778	ko02020,map02020	M00479			ko00000,ko00001,ko00002,ko01000,ko01001,ko02022				Bacteria	1TSUE@1239,4HB9N@91061,COG4585@1,COG4585@2	NA|NA|NA	T	Histidine kinase
NHHNPPIF_01461	904306.HMPREF9192_1103	1.3e-100	372.5	Bacilli	desR			ko:K02479,ko:K07693	ko02020,map02020	M00479			ko00000,ko00001,ko00002,ko02022				Bacteria	1TVTF@1239,4HAJW@91061,COG2197@1,COG2197@2	NA|NA|NA	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHHNPPIF_01462	264199.stu1316	4.6e-59	234.2	Bacilli	sdaAB		4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230		R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000				Bacteria	1U8TZ@1239,4HBD6@91061,COG1760@1,COG1760@2	NA|NA|NA	E	L-serine dehydratase
NHHNPPIF_01463	264199.stu1315	2.5e-308	1063.9	Bacilli	hutU		4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPZ9@1239,4H9NH@91061,COG2987@1,COG2987@2	NA|NA|NA	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NHHNPPIF_01464	264199.stu1314	1.6e-205	721.8	Bacilli				ko:K09703					ko00000				Bacteria	1TR39@1239,4HBM2@91061,COG3535@1,COG3535@2	NA|NA|NA	S	Protein of unknown function (DUF917)
NHHNPPIF_01465	264199.stu1313	2.5e-278	964.1	Bacilli	hutH		4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPCW@1239,4H9YS@91061,COG2986@1,COG2986@2	NA|NA|NA	E	Histidine ammonia-lyase
NHHNPPIF_01466	264199.stu1312	4.3e-102	377.5	Bacilli	proWZ			ko:K05846	ko02010,map02010	M00209			ko00000,ko00001,ko00002,ko02000	3.A.1.12			Bacteria	1V41S@1239,4HH8U@91061,COG1174@1,COG1174@2	NA|NA|NA	P	ABC transporter (Permease
NHHNPPIF_01467	264199.stu1311	3.8e-165	587.4	Bacilli	proX			ko:K05845	ko02010,map02010	M00209			ko00000,ko00001,ko00002,ko02000	3.A.1.12			Bacteria	1TQ7D@1239,4HESS@91061,COG1732@1,COG1732@2	NA|NA|NA	M	ABC transporter, substrate-binding protein, QAT family
NHHNPPIF_01468	264199.stu1310	1.6e-137	495.4	Bacilli	proV			ko:K05847	ko02010,map02010	M00209			ko00000,ko00001,ko00002,ko02000	3.A.1.12			Bacteria	1TPV8@1239,4H9SI@91061,COG1125@1,COG1125@2	NA|NA|NA	E	abc transporter atp-binding protein
NHHNPPIF_01469	264199.stu1309	4.4e-88	330.9	Bacilli	proW			ko:K05846	ko02010,map02010	M00209			ko00000,ko00001,ko00002,ko02000	3.A.1.12			Bacteria	1V24D@1239,4IQR7@91061,COG1174@1,COG1174@2	NA|NA|NA	P	Binding-protein-dependent transport system inner membrane component
NHHNPPIF_01470	264199.stu1307	1.5e-21	108.6	Firmicutes	yjjG	GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006206,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008655,GO:0009058,GO:0009112,GO:0009410,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019856,GO:0019859,GO:0030145,GO:0034641,GO:0034654,GO:0042221,GO:0042578,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.1.3.102,3.1.3.104,3.1.3.5,3.8.1.2	ko:K01560,ko:K07025,ko:K08723,ko:K20862	ko00230,ko00240,ko00361,ko00625,ko00740,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00740,map00760,map01100,map01110,map01120	M00125	R00183,R00511,R00548,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287,R07280	RC00017,RC00697	ko00000,ko00001,ko00002,ko01000			iECNA114_1301.ECNA114_4614	Bacteria	1TWM7@1239,COG1011@1,COG1011@2	NA|NA|NA	E	hydrolase
NHHNPPIF_01471	264199.stu1307	3.9e-37	160.2	Firmicutes	yjjG	GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006206,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008655,GO:0009058,GO:0009112,GO:0009410,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019856,GO:0019859,GO:0030145,GO:0034641,GO:0034654,GO:0042221,GO:0042578,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.1.3.102,3.1.3.104,3.1.3.5,3.8.1.2	ko:K01560,ko:K07025,ko:K08723,ko:K20862	ko00230,ko00240,ko00361,ko00625,ko00740,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00740,map00760,map01100,map01110,map01120	M00125	R00183,R00511,R00548,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287,R07280	RC00017,RC00697	ko00000,ko00001,ko00002,ko01000			iECNA114_1301.ECNA114_4614	Bacteria	1TWM7@1239,COG1011@1,COG1011@2	NA|NA|NA	E	hydrolase
NHHNPPIF_01472	322159.STER_1280	0.0	1182.9	Bacilli	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391		ko:K03703	ko03420,map03420				ko00000,ko00001,ko03400				Bacteria	1TP4B@1239,4H9QH@91061,COG0322@1,COG0322@2	NA|NA|NA	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NHHNPPIF_01473	264199.stu1305	6.4e-276	956.1	Bacilli	cls			ko:K06131,ko:K06915	ko00564,ko01100,map00564,map01100		R07390	RC00017	ko00000,ko00001,ko01000				Bacteria	1TPKY@1239,4H9TI@91061,COG1502@1,COG1502@2	NA|NA|NA	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHHNPPIF_01474	264199.stu0372	1e-165	589.3	Bacilli	ppaC	GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464	3.6.1.1	ko:K15986	ko00190,map00190				ko00000,ko00001,ko01000				Bacteria	1TPH6@1239,4H9T8@91061,COG1227@1,COG1227@2	NA|NA|NA	C	inorganic pyrophosphatase
NHHNPPIF_01475	322159.STER_1518	1.5e-97	362.1	Bacilli	XK27_07830		2.3.1.128	ko:K03790					ko00000,ko01000,ko03009				Bacteria	1V576@1239,4HH6U@91061,COG1670@1,COG1670@2	NA|NA|NA	J	Acetyltransferase GNAT Family
NHHNPPIF_01476	322159.STER_1517	2.8e-230	804.3	Bacilli	ytoI												Bacteria	1TPU6@1239,4HB62@91061,COG4109@1,COG4109@2	NA|NA|NA	K	transcriptional regulator containing CBS domains
NHHNPPIF_01477	322159.STER_1516	7.2e-166	589.7	Bacilli	map	GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605	3.4.11.18	ko:K01265					ko00000,ko01000,ko01002				Bacteria	1TQC1@1239,4H9S9@91061,COG0024@1,COG0024@2	NA|NA|NA	E	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
NHHNPPIF_01478	322159.STER_1515	2.4e-159	568.2	Bacilli	rbn			ko:K07058					ko00000				Bacteria	1U7HM@1239,4H9MJ@91061,COG1295@1,COG1295@2	NA|NA|NA	E	Belongs to the UPF0761 family
NHHNPPIF_01479	264199.stu1555	1.3e-85	322.4	Bacilli	ccl	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944											Bacteria	1V22G@1239,4HGG2@91061,COG4708@1,COG4708@2	NA|NA|NA	S	cog cog4708
NHHNPPIF_01480	264199.stu1554	0.0	1238.4	Bacilli	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430		R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400				Bacteria	1TPQ3@1239,4HA1D@91061,COG0272@1,COG0272@2	NA|NA|NA	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NHHNPPIF_01481	322159.STER_1512	1.9e-186	658.3	Bacilli	yegS	GO:0001727,GO:0003674,GO:0003824,GO:0004143,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0030258,GO:0044237,GO:0044238,GO:0044255,GO:0046834,GO:0071704	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110		R02240	RC00002,RC00017	ko00000,ko00001,ko01000				Bacteria	1TQAU@1239,4H9WD@91061,COG1597@1,COG1597@2	NA|NA|NA	I	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NHHNPPIF_01482	264199.stu1552	1.7e-119	435.3	Bacilli	ribD		1.1.1.193,3.5.4.26	ko:K00082,ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000			iLJ478.TM1828	Bacteria	1UHQR@1239,4IS6G@91061,COG1985@1,COG1985@2	NA|NA|NA	L	Transposase DDE domain
NHHNPPIF_01483	322159.STER_1509	2.1e-74	285.0	Firmicutes													Bacteria	1V99E@1239,COG4708@1,COG4708@2	NA|NA|NA	S	QueT transporter
NHHNPPIF_01484	264199.stu1550	1e-156	559.3	Bacilli	xth	GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.11.2	ko:K01142	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	1TPFB@1239,4HAIU@91061,COG0708@1,COG0708@2	NA|NA|NA	L	exodeoxyribonuclease III
NHHNPPIF_01485	322159.STER_1507	6.9e-172	609.8	Bacilli	tehB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0010035,GO:0016740,GO:0016741,GO:0032259,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046690,GO:0050896	2.1.1.265	ko:K03647,ko:K16868					ko00000,ko01000				Bacteria	1TSZK@1239,4HJT1@91061,COG0500@1,COG0500@2,COG3615@1,COG3615@2	NA|NA|NA	PQ	tellurite resistance protein tehb
NHHNPPIF_01486	1046629.Ssal_00517	2.4e-43	181.0	Bacilli	rpsP	GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02959	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011,ko03029				Bacteria	1VA0X@1239,4HKNN@91061,COG0228@1,COG0228@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bS16 family
NHHNPPIF_01487	264199.stu1547	4.1e-37	160.2	Bacteria	ylqC			ko:K06960					ko00000				Bacteria	COG1837@1,COG1837@2	NA|NA|NA	L	Belongs to the UPF0109 family
NHHNPPIF_01488	264199.stu1546	5.5e-239	833.2	Bacilli	folC		6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000			iLJ478.TM0166	Bacteria	1TPX5@1239,4HBJM@91061,COG0285@1,COG0285@2	NA|NA|NA	H	Belongs to the folylpolyglutamate synthase family
NHHNPPIF_01489	322159.STER_1503	0.0	1163.7	Bacilli	ydaO	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039											Bacteria	1TQE1@1239,4HAZH@91061,COG0531@1,COG0531@2	NA|NA|NA	E	amino acid
NHHNPPIF_01490	264199.stu1544	1e-99	369.4	Bacilli	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000			iNJ661.Rv3609c	Bacteria	1TRNM@1239,4HAXS@91061,COG0302@1,COG0302@2	NA|NA|NA	F	gtp cyclohydrolase
NHHNPPIF_01491	264199.stu1543	7e-147	526.6	Bacilli	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000			iHN637.CLJU_RS03115	Bacteria	1TPKT@1239,4H9SY@91061,COG0294@1,COG0294@2	NA|NA|NA	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NHHNPPIF_01492	264199.stu1542	3e-297	1026.9	Bacilli	amy		3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973		R02108,R02112,R11262		ko00000,ko00001,ko01000		GH13		Bacteria	1TRKZ@1239,4HC8C@91061,COG0366@1,COG0366@2	NA|NA|NA	G	Belongs to the glycosyl hydrolase 13 family
NHHNPPIF_01493	322159.STER_1499	7.6e-61	239.6	Bacilli	folB		1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8	ko:K00796,ko:K00950,ko:K01633,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503,R03504,R11037,R11073	RC00002,RC00017,RC00121,RC00721,RC00842,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000				Bacteria	1VA0I@1239,4HKKK@91061,COG1539@1,COG1539@2	NA|NA|NA	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NHHNPPIF_01494	322159.STER_1498	2.9e-87	327.8	Bacilli	folK		2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000				Bacteria	1V6PR@1239,4HIMG@91061,COG0801@1,COG0801@2	NA|NA|NA	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NHHNPPIF_01495	322159.STER_1497	7.8e-171	606.3	Bacilli	murB		1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100		R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011				Bacteria	1TP3W@1239,4HAD8@91061,COG0812@1,COG0812@2	NA|NA|NA	M	cell wall formation
NHHNPPIF_01496	322159.STER_1496	2.8e-213	747.7	Bacilli	potA		3.6.3.30,3.6.3.31	ko:K02010,ko:K11072	ko02010,map02010	M00190,M00299			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11.1		iSB619.SA_RS05380	Bacteria	1TP2M@1239,4H9MS@91061,COG3842@1,COG3842@2	NA|NA|NA	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NHHNPPIF_01497	264199.stu1537	3.7e-140	504.2	Bacilli	potB			ko:K11071	ko02010,map02010	M00299			ko00000,ko00001,ko00002,ko02000	3.A.1.11.1			Bacteria	1TQ7Z@1239,4HAYS@91061,COG1176@1,COG1176@2	NA|NA|NA	P	ABC-type spermidine putrescine transport system, permease component I
NHHNPPIF_01498	322159.STER_1494	3e-134	484.6	Bacilli	potC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008519,GO:0015075,GO:0015101,GO:0015203,GO:0015399,GO:0015405,GO:0015417,GO:0015595,GO:0015606,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0015848,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072488,GO:0098533,GO:0098655,GO:0098796,GO:0098797,GO:1902047,GO:1902494,GO:1902495,GO:1903711,GO:1904949,GO:1990351		ko:K11070	ko02010,map02010	M00299			ko00000,ko00001,ko00002,ko02000	3.A.1.11.1		iSBO_1134.SBO_1939	Bacteria	1V0VD@1239,4H9ZC@91061,COG1177@1,COG1177@2	NA|NA|NA	P	ABC-type spermidine putrescine transport system, permease component II
NHHNPPIF_01499	264199.stu1535	2.3e-206	724.5	Bacilli	potD			ko:K11069	ko02010,map02010	M00299			ko00000,ko00001,ko00002,ko02000	3.A.1.11.1		iSB619.SA_RS05395	Bacteria	1TPY1@1239,4HAET@91061,COG0687@1,COG0687@2	NA|NA|NA	P	spermidine putrescine ABC transporter
NHHNPPIF_01500	904306.HMPREF9192_0867	1.3e-19	102.1	Bacilli	XK27_08050												Bacteria	1TPXU@1239,4HGRC@91061,COG0330@1,COG0330@2	NA|NA|NA	O	HflC and HflK could regulate a protease
NHHNPPIF_01501	1046629.Ssal_00531	1.7e-36	158.3	Bacilli	XK27_08050												Bacteria	1TPXU@1239,4HGRC@91061,COG0330@1,COG0330@2	NA|NA|NA	O	HflC and HflK could regulate a protease
NHHNPPIF_01502	264199.stu1533	1.7e-47	195.3	Bacteria	XK27_08050												Bacteria	COG0330@1,COG0330@2	NA|NA|NA	O	stress-induced mitochondrial fusion
NHHNPPIF_01503	264199.stu1532	8.1e-72	276.2	Bacilli	gloA		4.4.1.5	ko:K01759,ko:K15772	ko00620,ko02010,map00620,map02010	M00491	R02530	RC00004,RC00740	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1.16,3.A.1.1.2			Bacteria	1V6K3@1239,4HJ7X@91061,COG0346@1,COG0346@2	NA|NA|NA	E	Lactoylglutathione lyase
NHHNPPIF_01504	264199.stu1530	4.1e-54	217.2	Bacilli													Bacteria	1TRQ7@1239,4HE30@91061,COG1940@1,COG1940@2	NA|NA|NA	GK	ROK family
NHHNPPIF_01505	264199.stu1530	4e-50	203.8	Bacilli													Bacteria	1TRQ7@1239,4HE30@91061,COG1940@1,COG1940@2	NA|NA|NA	GK	ROK family
NHHNPPIF_01506	322159.STER_1489	1.9e-208	731.5	Bacilli	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007				Bacteria	1TP6Y@1239,4HATT@91061,COG1932@1,COG1932@2	NA|NA|NA	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NHHNPPIF_01507	264199.stu1528	1.3e-104	385.6	Bacilli	wecD												Bacteria	1UIW7@1239,4ISU9@91061,COG1247@1,COG1247@2	NA|NA|NA	M	Acetyltransferase (GNAT) domain
NHHNPPIF_01508	322159.STER_1487	1.5e-219	768.5	Bacilli	serA		1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147				Bacteria	1V410@1239,4H9PH@91061,COG0111@1,COG0111@2	NA|NA|NA	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHHNPPIF_01509	904306.HMPREF9192_0874	5.3e-56	223.4	Bacteria	ogt	GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	2.1.1.63,3.2.2.20	ko:K00567,ko:K01246	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	COG0350@1,COG0350@2	NA|NA|NA	L	methylated-DNA-[protein]-cysteine S-methyltransferase activity
NHHNPPIF_01510	264199.stu1525	3.2e-59	234.2	Bacilli	arsC		1.20.4.1	ko:K00537,ko:K16509					ko00000,ko01000				Bacteria	1VA5Q@1239,4HKQQ@91061,COG1393@1,COG1393@2	NA|NA|NA	P	Belongs to the ArsC family
NHHNPPIF_01512	322159.STER_1483	7.7e-56	223.0	Firmicutes	lrgA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K06518					ko00000,ko02000	1.E.14.2			Bacteria	1VEN4@1239,COG1380@1,COG1380@2	NA|NA|NA	S	Effector of murein hydrolase LrgA
NHHNPPIF_01513	322159.STER_1482	2.2e-117	428.3	Bacilli	lrgB												Bacteria	1TRGN@1239,4HF0M@91061,COG1346@1,COG1346@2	NA|NA|NA	M	effector of murein hydrolase
NHHNPPIF_01514	264199.stu1522	1.6e-97	362.1	Bacilli			3.1.3.18	ko:K01091,ko:K07025	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130		R01334	RC00017	ko00000,ko00001,ko01000				Bacteria	1V421@1239,4HHYH@91061,COG0546@1,COG0546@2	NA|NA|NA	S	IA, variant 1
NHHNPPIF_01515	264199.stu1521	0.0	1272.3	Bacilli	gyrB	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	5.99.1.3	ko:K02470,ko:K02622					ko00000,ko01000,ko02048,ko03032,ko03036,ko03400				Bacteria	1TQ0R@1239,4H9Y6@91061,COG0187@1,COG0187@2	NA|NA|NA	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHHNPPIF_01516	264199.stu1520	6.2e-302	1042.7	Bacilli	ezrA	GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047		ko:K06286,ko:K07158					ko00000,ko03036				Bacteria	1TQR7@1239,4HA15@91061,COG4477@1,COG4477@2	NA|NA|NA	D	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NHHNPPIF_01517	264199.stu1519	4.4e-115	420.6	Bacilli	serB		3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009				Bacteria	1V9R7@1239,4HTNE@91061,COG0560@1,COG0560@2	NA|NA|NA	E	phosphoserine phosphatase
NHHNPPIF_01518	322159.STER_1477	0.0	2706.8	Bacilli	cas9			ko:K09952					ko00000,ko01000,ko02048				Bacteria	1TPSD@1239,4HE0R@91061,COG3513@1,COG3513@2	NA|NA|NA	L	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NHHNPPIF_01519	322159.STER_1476	1.5e-163	582.0	Bacilli	cas1			ko:K15342					ko00000,ko02048,ko03400				Bacteria	1TT0J@1239,4HC5E@91061,COG1518@1,COG1518@2	NA|NA|NA	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NHHNPPIF_01520	322159.STER_1475	3.5e-52	210.7	Bacilli	cas2			ko:K09951					ko00000,ko02048				Bacteria	1VEH4@1239,4HNYR@91061,COG3512@1,COG3512@2	NA|NA|NA	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NHHNPPIF_01521	322159.STER_1474	5.6e-110	403.7	Bacilli	csn2			ko:K19137					ko00000,ko02048				Bacteria	1V1IF@1239,298VG@1,2ZVZK@2,4HGGM@91061	NA|NA|NA	S	CRISPR-associated protein (Cas_Csn2)
NHHNPPIF_01523	264199.stu1517	3.8e-154	550.8	Firmicutes													Bacteria	1TYSF@1239,COG0697@1,COG0697@2	NA|NA|NA	EG	Permeases of the drug metabolite transporter (DMT) superfamily
NHHNPPIF_01525	322159.STER_1470	3.9e-50	203.8	Bacteria	ycaO			ko:K06889,ko:K07397,ko:K09136					ko00000,ko03009				Bacteria	COG1765@1,COG1765@2	NA|NA|NA	O	OsmC-like protein
NHHNPPIF_01526	264199.stu1516	1.6e-64	251.9	Bacilli	paaI			ko:K02614	ko00360,map00360		R09840	RC00004,RC00014	ko00000,ko00001,ko01000				Bacteria	1VN0K@1239,4HM66@91061,COG2050@1,COG2050@2	NA|NA|NA	Q	protein possibly involved in aromatic compounds catabolism
NHHNPPIF_01529	322159.STER_1466	6.4e-131	473.4	Bacilli	rsuA	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183					ko00000,ko01000,ko03009				Bacteria	1TQZ2@1239,4H9VU@91061,COG1187@1,COG1187@2	NA|NA|NA	J	Belongs to the pseudouridine synthase RsuA family
NHHNPPIF_01530	264199.stu1504	1.4e-248	865.1	Bacilli	obg	GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043021,GO:0043022,GO:0043167,GO:0043168,GO:0043934,GO:0044424,GO:0044464,GO:0044877,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363		ko:K03979					ko00000,ko01000,ko03009				Bacteria	1TPX7@1239,4H9P8@91061,COG0536@1,COG0536@2	NA|NA|NA	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NHHNPPIF_01531	1214217.ALNF01000018_gene931	1.1e-16	92.0	Streptococcus suis	XK27_00735												Bacteria	1U94Q@1239,1WTRS@1307,29R2M@1,30C3R@2,4IJ5T@91061	NA|NA|NA		
NHHNPPIF_01532	322159.STER_1462	6e-137	493.4	Bacilli	glnQ		3.6.3.21	ko:K02028,ko:K10038	ko02010,map02010	M00227,M00236			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.2			Bacteria	1TNYD@1239,4H9WY@91061,COG1126@1,COG1126@2	NA|NA|NA	E	abc transporter atp-binding protein
NHHNPPIF_01533	322159.STER_1461	1.3e-149	535.8	Bacilli	glnP			ko:K02029,ko:K02030,ko:K10040,ko:K17073,ko:K17074	ko02010,map02010	M00228,M00236,M00589			ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.20			Bacteria	1TQUG@1239,4HAJ5@91061,COG0765@1,COG0765@2,COG0834@1,COG0834@2	NA|NA|NA	P	ABC-type amino acid transport signal transduction systems periplasmic component domain
NHHNPPIF_01534	264199.stu1501	1.8e-237	828.2	Bacilli	glnP			ko:K02029,ko:K02030,ko:K10040,ko:K17073,ko:K17074	ko02010,map02010	M00228,M00236,M00589			ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.20			Bacteria	1TQUG@1239,4HAJ5@91061,COG0765@1,COG0765@2,COG0834@1,COG0834@2	NA|NA|NA	P	ABC-type amino acid transport signal transduction systems periplasmic component domain
NHHNPPIF_01535	904306.HMPREF9192_0897	2.4e-33	147.9	Bacilli				ko:K07052					ko00000				Bacteria	1VA8S@1239,4IQWI@91061,COG1266@1,COG1266@2	NA|NA|NA	S	CAAX amino terminal protease family protein
NHHNPPIF_01536	904306.HMPREF9192_0897	4.3e-82	310.8	Bacilli				ko:K07052					ko00000				Bacteria	1VA8S@1239,4IQWI@91061,COG1266@1,COG1266@2	NA|NA|NA	S	CAAX amino terminal protease family protein
NHHNPPIF_01538	322159.STER_1457	0.0	1288.5	Bacilli	uvrB			ko:K03702,ko:K08999	ko03420,map03420				ko00000,ko00001,ko03400				Bacteria	1TPKB@1239,4HB81@91061,COG0556@1,COG0556@2	NA|NA|NA	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NHHNPPIF_01539	322159.STER_1456	2.9e-84	317.8	Firmicutes	mutT		3.6.1.55	ko:K03574					ko00000,ko01000,ko03400				Bacteria	1V3MM@1239,COG1051@1,COG1051@2	NA|NA|NA	F	Nudix family
NHHNPPIF_01540	264199.stu1495	1.7e-140	505.4	Firmicutes				ko:K02030,ko:K17073,ko:K17074	ko02010,map02010	M00236,M00589			ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.20			Bacteria	1TT16@1239,COG0834@1,COG0834@2	NA|NA|NA	ET	Belongs to the bacterial solute-binding protein 3 family
NHHNPPIF_01541	322159.STER_1454	8.8e-134	483.0	Bacilli				ko:K02030,ko:K17073,ko:K17074	ko02010,map02010	M00236,M00589			ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.20			Bacteria	1TT16@1239,4HJ2R@91061,COG0834@1,COG0834@2	NA|NA|NA	ET	ABC transporter
NHHNPPIF_01542	264199.stu1493	1.7e-199	701.8	Bacilli	arcT		2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230		R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007				Bacteria	1TQPD@1239,4HE7P@91061,COG0436@1,COG0436@2	NA|NA|NA	E	Aminotransferase
NHHNPPIF_01543	322159.STER_1452	4.2e-136	490.7	Bacilli	gltS			ko:K02030,ko:K17073,ko:K17074	ko02010,map02010	M00236,M00589			ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.20			Bacteria	1TT16@1239,4HD16@91061,COG0834@1,COG0834@2	NA|NA|NA	ET	Belongs to the bacterial solute-binding protein 3 family
NHHNPPIF_01544	1046629.Ssal_00586	1.2e-19	101.7	Bacilli	rpsU	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02970	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1VEHU@1239,4HNPV@91061,COG0828@1,COG0828@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bS21 family
NHHNPPIF_01545	873449.STRCR_1157	1.5e-46	192.2	Bacilli	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066		ko:K03282					ko00000,ko02000	1.A.22.1			Bacteria	1VA14@1239,4HKIA@91061,COG1970@1,COG1970@2	NA|NA|NA	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NHHNPPIF_01546	264199.stu1489	0.0	1156.0	Bacilli	dnaG			ko:K02316	ko03030,map03030				ko00000,ko00001,ko01000,ko03032				Bacteria	1TQ0X@1239,4HAG2@91061,COG0358@1,COG0358@2	NA|NA|NA	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NHHNPPIF_01547	322159.STER_1448	1.1e-201	709.1	Bacilli	sigA	GO:0000988,GO:0000990,GO:0001098,GO:0001101,GO:0001108,GO:0001666,GO:0002791,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0016020,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032879,GO:0032880,GO:0036293,GO:0040007,GO:0042221,GO:0043175,GO:0043254,GO:0044087,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051173,GO:0051223,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070063,GO:0070201,GO:0070482,GO:0071944,GO:0080090,GO:0090087,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:1903530,GO:2000112,GO:2000142,GO:2001141		ko:K03086,ko:K03087	ko02026,ko05111,map02026,map05111				ko00000,ko00001,ko03021				Bacteria	1TPD6@1239,4HB1H@91061,COG0568@1,COG0568@2	NA|NA|NA	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NHHNPPIF_01548	264199.stu1487	3.4e-55	220.7	Bacilli	yitW			ko:K02612	ko00360,ko01120,map00360,map01120		R09838	RC02690	ko00000,ko00001				Bacteria	1V9YV@1239,4HKC6@91061,COG2151@1,COG2151@2	NA|NA|NA	K	metal-sulfur cluster biosynthetic enzyme
NHHNPPIF_01549	322159.STER_1446	9.8e-169	599.4	Bacilli	yfdH			ko:K12999,ko:K20534					ko00000,ko01000,ko01003,ko01005,ko02000	4.D.2.1.9	GT2		Bacteria	1TPR3@1239,4HC2Z@91061,COG0463@1,COG0463@2	NA|NA|NA	M	COG0463, glycosyltransferases involved in cell wall biogenesis
NHHNPPIF_01550	264199.stu1484	1.9e-245	854.7	Firmicutes													Bacteria	1VPDR@1239,2DSN8@1,33GRU@2	NA|NA|NA		
NHHNPPIF_01551	264199.stu1483	4e-161	573.9	Bacilli	rfbD		1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP71@1239,4HBXF@91061,COG1091@1,COG1091@2	NA|NA|NA	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NHHNPPIF_01552	904306.HMPREF9192_0915	8.2e-219	766.1	Bacilli	amrA												Bacteria	1V1RP@1239,4IR8D@91061,COG2244@1,COG2244@2	NA|NA|NA	S	membrane protein involved in the export of O-antigen and teichoic acid
NHHNPPIF_01553	322159.STER_1442	6e-185	653.3	Firmicutes													Bacteria	1UJE4@1239,COG1216@1,COG1216@2	NA|NA|NA	S	Glycosyltransferase like family 2
NHHNPPIF_01554	322159.STER_1441	9.5e-183	646.0	Bacilli	cpsIaJ												Bacteria	1V3XP@1239,4HQNP@91061,COG1216@1,COG1216@2	NA|NA|NA	S	Glycosyltransferase like family 2
NHHNPPIF_01555	322159.STER_1440	6.9e-130	469.9	Bacilli	arnC			ko:K00786					ko00000,ko01000				Bacteria	1UHQZ@1239,4IS6R@91061,COG1215@1,COG1215@2	NA|NA|NA	M	group 2 family protein
NHHNPPIF_01556	1046629.Ssal_00599	4.6e-42	177.2	Firmicutes				ko:K09153					ko00000				Bacteria	1VPQZ@1239,2EVMS@1,33P1S@2	NA|NA|NA	S	Uncharacterized conserved protein (DUF2304)
NHHNPPIF_01557	322159.STER_1438	2.4e-152	544.7	Firmicutes			2.4.1.60	ko:K07011,ko:K13005					ko00000,ko01000,ko01003,ko01005				Bacteria	1UI19@1239,COG1216@1,COG1216@2	NA|NA|NA	S	Glycosyltransferase group 2 family protein
NHHNPPIF_01558	322159.STER_1437	2.3e-228	797.7	Bacilli	rgpA			ko:K12996					ko00000,ko01000,ko01003,ko01005		GT4		Bacteria	1V7K7@1239,4HA9A@91061,COG0438@1,COG0438@2	NA|NA|NA	M	Domain of unknown function (DUF1972)
NHHNPPIF_01559	322159.STER_1436	6.4e-176	623.2	Bacilli	rgpB			ko:K12997					ko00000,ko01000,ko01003,ko01005		GT2		Bacteria	1V7IQ@1239,4HK7R@91061,COG0463@1,COG0463@2	NA|NA|NA	M	Glycosyltransferase, group 2 family protein
NHHNPPIF_01560	322159.STER_1435	1.8e-142	511.9	Bacilli	rgpC			ko:K01992		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1V1J2@1239,4HI7C@91061,COG1682@1,COG1682@2	NA|NA|NA	GM	Transport permease protein
NHHNPPIF_01561	322159.STER_1434	6.4e-229	799.7	Bacilli	rgpD		3.6.3.38	ko:K01990,ko:K09689,ko:K09691	ko02010,map02010	M00249,M00250,M00254			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.101,3.A.1.103			Bacteria	1TQKK@1239,4HC6N@91061,COG1134@1,COG1134@2	NA|NA|NA	P	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NHHNPPIF_01562	322159.STER_1433	4.5e-305	1053.1	Bacteria				ko:K00754					ko00000,ko01000		GT4		Bacteria	COG0438@1,COG0438@2	NA|NA|NA	M	transferase activity, transferring glycosyl groups
NHHNPPIF_01563	322159.STER_1432	0.0	1198.3	Bacilli	rgpF			ko:K07272					ko00000,ko01000,ko01003,ko01005				Bacteria	1V95X@1239,4HIXP@91061,COG3754@1,COG3754@2	NA|NA|NA	M	Rhamnan synthesis protein F
NHHNPPIF_01564	322159.STER_1431	1.7e-268	931.4	Bacteria													Bacteria	COG4713@1,COG4713@2	NA|NA|NA	M	Psort location CytoplasmicMembrane, score
NHHNPPIF_01565	322159.STER_1430	1.2e-115	422.5	Bacilli	radC			ko:K03630					ko00000				Bacteria	1TQ3K@1239,4HB1W@91061,COG2003@1,COG2003@2	NA|NA|NA	E	Belongs to the UPF0758 family
NHHNPPIF_01566	904306.HMPREF9192_0931	2.7e-123	448.0	Bacilli	puuD			ko:K07010					ko00000,ko01002				Bacteria	1V1KC@1239,4HI59@91061,COG2071@1,COG2071@2	NA|NA|NA	T	peptidase C26
NHHNPPIF_01567	322159.STER_1428	4.7e-117	427.2	Bacilli	rex			ko:K01926					ko00000,ko03000				Bacteria	1TSMR@1239,4HB7Q@91061,COG2344@1,COG2344@2	NA|NA|NA	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NHHNPPIF_01568	264199.stu1462	1e-57	229.2	Bacilli	XK27_04120												Bacteria	1VDSF@1239,2DHWG@1,32U9W@2,4HP9N@91061	NA|NA|NA	S	Putative amino acid metabolism
NHHNPPIF_01569	264199.stu1461	3.2e-206	724.2	Bacilli	iscS		2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122		R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029				Bacteria	1TP21@1239,4HA6H@91061,COG1104@1,COG1104@2	NA|NA|NA	E	Cysteine desulfurase
NHHNPPIF_01570	322159.STER_1425	1.2e-177	629.0	Bacilli	prs		2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000			iAF987.Gmet_2848	Bacteria	1TQ4I@1239,4HDRN@91061,COG0462@1,COG0462@2	NA|NA|NA	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHHNPPIF_01571	264199.stu1458	1.5e-103	382.1	Bacilli	yjbK												Bacteria	1VA56@1239,4HMNE@91061,COG4116@1,COG4116@2	NA|NA|NA	S	Adenylate cyclase
NHHNPPIF_01572	264199.stu1459	1.4e-119	435.6	Bacilli	yjbM		2.7.6.5	ko:K07816	ko00230,map00230		R00429	RC00002,RC00078	ko00000,ko00001,ko01000				Bacteria	1TQ2F@1239,4HA3Q@91061,COG2357@1,COG2357@2	NA|NA|NA	S	Gtp pyrophosphokinase
NHHNPPIF_01573	264199.stu1457	3.7e-151	540.8	Bacilli	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100		R00104	RC00002,RC00078	ko00000,ko00001,ko01000			iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895	Bacteria	1TRB3@1239,4HB08@91061,COG0061@1,COG0061@2	NA|NA|NA	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NHHNPPIF_01574	264199.stu1456	1.1e-172	612.5	Bacilli	rluD	GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180					ko00000,ko01000,ko03009,ko03016			iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432	Bacteria	1TS1T@1239,4HBRY@91061,COG0564@1,COG0564@2	NA|NA|NA	J	Responsible for synthesis of pseudouridine from uracil
NHHNPPIF_01575	264199.stu1455	5.9e-180	636.7	Bacilli	pta		2.3.1.8,3.6.3.21	ko:K00625,ko:K02028,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00236,M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3		iSB619.SA_RS03155	Bacteria	1TPQ0@1239,4H9VH@91061,COG0280@1,COG0280@2	NA|NA|NA	C	phosphate acetyltransferase
NHHNPPIF_01576	1316408.HSISM1_560	6.1e-37	159.8	Bacilli				ko:K07483					ko00000				Bacteria	1VDX9@1239,4HRT2@91061,COG2963@1,COG2963@2	NA|NA|NA	L	Transposase
NHHNPPIF_01577	322159.STER_1630	2.8e-137	494.6	Bacilli	cppA												Bacteria	1VMPM@1239,4HSVM@91061,COG0346@1,COG0346@2	NA|NA|NA	E	CppA N-terminal
NHHNPPIF_01578	264199.stu1667	3.8e-184	650.6	Bacilli	ampC												Bacteria	1TNZX@1239,4IPJT@91061,COG1680@1,COG1680@2	NA|NA|NA	V	COG1680 Beta-lactamase class C and other penicillin binding proteins
NHHNPPIF_01579	762051.LKI_10701	3.1e-31	140.6	Leuconostocaceae													Bacteria	1VZDZ@1239,2DY5Q@1,34896@2,4AY9W@81850,4HZ9A@91061	NA|NA|NA		
NHHNPPIF_01580	322159.STER_1628	3e-116	424.5	Bacilli	ybbL	GO:0005575,GO:0005623,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0016020,GO:0019725,GO:0030003,GO:0042592,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071944,GO:0098771		ko:K02065,ko:K02068	ko02010,map02010	M00210,M00211,M00669,M00670			ko00000,ko00001,ko00002,ko02000	3.A.1.27			Bacteria	1V3DQ@1239,4HHGU@91061,COG4619@1,COG4619@2	NA|NA|NA	S	abc transporter atp-binding protein
NHHNPPIF_01581	264199.stu1665	2.3e-123	448.4	Bacilli	ybbM	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771		ko:K02069		M00211			ko00000,ko00002,ko02000	9.B.25.1			Bacteria	1UY1N@1239,4HDM4@91061,COG0390@1,COG0390@2	NA|NA|NA	S	transport system, permease component
NHHNPPIF_01582	264199.stu1664	7.6e-118	429.9	Bacteria	XK27_05540												Bacteria	COG1434@1,COG1434@2	NA|NA|NA	S	Gram-negative-bacterium-type cell wall biogenesis
NHHNPPIF_01583	203120.LEUM_A08	4.8e-58	230.3	Leuconostocaceae				ko:K04763					ko00000,ko03036				Bacteria	1VEIE@1239,4AX2E@81850,4HK3N@91061,COG0582@1,COG0582@2	NA|NA|NA	L	Phage integrase family
NHHNPPIF_01584	264199.stu1663	1.2e-32	145.2	Bacteria				ko:K04763					ko00000,ko03036				Bacteria	COG0582@1,COG0582@2	NA|NA|NA	L	DNA integration
NHHNPPIF_01585	264199.stu1662	1e-31	142.1	Bacilli				ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	1V5Y6@1239,4HHGT@91061,COG1196@1,COG1196@2	NA|NA|NA	D	nuclear chromosome segregation
NHHNPPIF_01586	264199.stu1661	3.9e-42	177.2	Bacilli				ko:K02004		M00258			ko00000,ko00002,ko02000	3.A.1			Bacteria	1V5Y6@1239,4HHGT@91061,COG1196@1,COG1196@2	NA|NA|NA	D	nuclear chromosome segregation
NHHNPPIF_01587	264199.stu1660	1.6e-09	68.2	Bacteria	hsdS_1		3.1.21.3	ko:K01154					ko00000,ko01000,ko02048				Bacteria	COG0732@1,COG0732@2	NA|NA|NA	V	type I restriction modification DNA specificity domain
NHHNPPIF_01588	322159.STER_1624	1e-84	319.3	Bacilli	yjcF			ko:K02348					ko00000				Bacteria	1VA2J@1239,4HKF5@91061,COG2153@1,COG2153@2	NA|NA|NA	S	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHHNPPIF_01589	264199.stu1658	5.8e-39	166.4	Bacilli	cah		4.2.1.1	ko:K01674	ko00910,map00910		R00132,R10092	RC02807	ko00000,ko00001,ko01000				Bacteria	1V16J@1239,4HA62@91061,COG3338@1,COG3338@2	NA|NA|NA	P	carbonic anhydrase
NHHNPPIF_01590	322159.STER_1623	7.2e-43	179.5	Bacilli	cah		4.2.1.1	ko:K01674	ko00910,map00910		R00132,R10092	RC02807	ko00000,ko00001,ko01000				Bacteria	1V16J@1239,4HA62@91061,COG3338@1,COG3338@2	NA|NA|NA	P	carbonic anhydrase
NHHNPPIF_01591	264199.stu1657	0.0	1551.2	Bacilli	pflB		2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120		R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000				Bacteria	1TPTF@1239,4H9RD@91061,COG1882@1,COG1882@2	NA|NA|NA	C	formate acetyltransferase'
NHHNPPIF_01592	322159.STER_1621	8.8e-201	706.1	Bacilli	dinB	GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031668,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904	2.7.7.7	ko:K02346					ko00000,ko01000,ko03400				Bacteria	1TP42@1239,4HADJ@91061,COG0389@1,COG0389@2	NA|NA|NA	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHHNPPIF_01594	264199.stu1654	4.8e-151	540.4	Bacilli	yxeM			ko:K02030		M00236			ko00000,ko00002,ko02000	3.A.1.3			Bacteria	1V7WQ@1239,4HK1Z@91061,COG0834@1,COG0834@2	NA|NA|NA	ET	ABC-type amino acid transport signal transduction systems, periplasmic component domain
NHHNPPIF_01595	264199.stu1653	2.3e-162	578.2	Bacilli	yxeN			ko:K02029,ko:K16959,ko:K16962	ko02010,map02010	M00236,M00585,M00586			ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.13			Bacteria	1UZ2C@1239,4HF77@91061,COG0765@1,COG0765@2	NA|NA|NA	P	ABC transporter (Permease
NHHNPPIF_01596	322159.STER_1617	1.3e-131	475.7	Bacilli	tcyN		3.6.3.21	ko:K02028,ko:K10010,ko:K16960,ko:K16963	ko02010,map02010	M00234,M00236,M00585,M00586			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.10,3.A.1.3.13,3.A.1.3.14			Bacteria	1TNYD@1239,4H9WY@91061,COG1126@1,COG1126@2	NA|NA|NA	E	abc transporter atp-binding protein
NHHNPPIF_01597	40041.SZO_03890	1.1e-09	68.9	Streptococcus dysgalactiae group													Bacteria	1M9T3@119603,1TXCH@1239,29I01@1,304X3@2,4I6AC@91061	NA|NA|NA	S	Protein of unknown function (DUF4059)
NHHNPPIF_01598	264199.stu1650	5.5e-172	610.1	Bacilli	trxB		1.8.1.9	ko:K00384	ko00450,map00450		R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000				Bacteria	1TNZS@1239,4HA4N@91061,COG0492@1,COG0492@2	NA|NA|NA	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NHHNPPIF_01599	264199.stu1649	4.3e-92	344.0	Bacilli	rsmD		2.1.1.171	ko:K08316			R07234	RC00003	ko00000,ko01000,ko03009				Bacteria	1V3JF@1239,4HGXT@91061,COG0742@1,COG0742@2	NA|NA|NA	L	Methyltransferase
NHHNPPIF_01600	264199.stu1648	1.7e-87	328.6	Bacilli	coaD		2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000				Bacteria	1V3MR@1239,4HH47@91061,COG0669@1,COG0669@2	NA|NA|NA	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NHHNPPIF_01601	264199.stu1647	7.8e-194	682.9	Bacilli	ylbL			ko:K07177	ko02024,map02024				ko00000,ko00001,ko01002				Bacteria	1TRUF@1239,4HBAY@91061,COG3480@1,COG3480@2	NA|NA|NA	T	Belongs to the peptidase S16 family
NHHNPPIF_01602	264199.stu1646	3.3e-180	637.5	Bacilli	yhcC	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540		ko:K07139					ko00000				Bacteria	1TQ57@1239,4H9N8@91061,COG1242@1,COG1242@2	NA|NA|NA	S	radical SAM protein
NHHNPPIF_01603	264199.stu1645	2e-97	361.7	Bacilli	ytqB		2.1.1.176	ko:K03500					ko00000,ko01000,ko03009				Bacteria	1UHQD@1239,4HIMC@91061,COG0144@1,COG0144@2	NA|NA|NA	J	(SAM)-dependent
NHHNPPIF_01605	264199.stu1643	0.0	1248.8	Bacilli	yjcE	GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600		ko:K03316					ko00000	2.A.36			Bacteria	1TR4G@1239,4HBJR@91061,COG0025@1,COG0025@2	NA|NA|NA	P	NhaP-type Na H and K H antiporters
NHHNPPIF_01606	264199.stu1642	3.9e-142	510.8	Bacilli	modF	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	3.6.3.21,3.6.3.34	ko:K02013,ko:K02028,ko:K05776	ko02010,map02010	M00189,M00236,M00240			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14,3.A.1.3			Bacteria	1TRR4@1239,4HB4U@91061,COG1119@1,COG1119@2	NA|NA|NA	P	abc transporter atp-binding protein
NHHNPPIF_01607	264199.stu1641	7.6e-239	832.8	Bacilli	hlyX			ko:K03699					ko00000,ko02042				Bacteria	1TPN0@1239,4H9SB@91061,COG1253@1,COG1253@2	NA|NA|NA	S	COG1253 Hemolysins and related proteins containing CBS domains
NHHNPPIF_01608	1046629.Ssal_00399	2.7e-151	541.2	Bacilli	pflA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0018307,GO:0019538,GO:0033554,GO:0036211,GO:0043170,GO:0043364,GO:0043365,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070283,GO:0071704,GO:1901564	1.97.1.4	ko:K04069			R04710		ko00000,ko01000			iECOK1_1307.ECOK1_0925,iEcE24377_1341.EcE24377A_0980,iEcSMS35_1347.EcSMS35_2219,iYL1228.KPN_00930	Bacteria	1TPK2@1239,4HACV@91061,COG1180@1,COG1180@2	NA|NA|NA	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NHHNPPIF_01610	264199.stu1637	6.9e-75	286.6	Bacilli	XK27_03180			ko:K03499,ko:K06149					ko00000,ko02000	2.A.38.1,2.A.38.4			Bacteria	1V3NY@1239,4HIP3@91061,COG0589@1,COG0589@2	NA|NA|NA	T	universal stress protein
NHHNPPIF_01611	322159.STER_1600	3.7e-240	837.0	Bacilli	alaA	GO:0003674,GO:0003824,GO:0004021,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0019842,GO:0030170,GO:0030632,GO:0032787,GO:0033554,GO:0036094,GO:0040007,GO:0042221,GO:0042851,GO:0042852,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0046677,GO:0047635,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.2,2.6.1.66	ko:K00814,ko:K14260	ko00220,ko00250,ko00290,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00220,map00250,map00290,map00710,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00171	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007			iNJ661.Rv0337c	Bacteria	1TP0J@1239,4HD83@91061,COG0436@1,COG0436@2	NA|NA|NA	E	Aminotransferase
NHHNPPIF_01612	264199.stu1635	2.8e-140	504.6	Bacilli	codY	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0044424,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141		ko:K03706					ko00000,ko03000				Bacteria	1TS7A@1239,4HA9U@91061,COG4465@1,COG4465@2	NA|NA|NA	K	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NHHNPPIF_01613	322159.STER_1598	9.8e-100	369.4	Bacilli	pncA			ko:K16788					ko00000,ko02000	2.A.88.5		iSB619.SA_RS09955	Bacteria	1V1CY@1239,4HFRS@91061,COG1335@1,COG1335@2	NA|NA|NA	Q	isochorismatase
NHHNPPIF_01614	264199.stu1633	4.1e-122	444.1	Bacilli	hlpA			ko:K02073	ko02010,map02010	M00238			ko00000,ko00001,ko00002,ko02000	3.A.1.24			Bacteria	1TQAS@1239,4HCTA@91061,COG1464@1,COG1464@2	NA|NA|NA	M	Belongs to the NlpA lipoprotein family
NHHNPPIF_01615	264199.stu1632	3.7e-60	237.3	Bacilli	msrA		1.8.4.11,1.8.4.12	ko:K07304,ko:K12267					ko00000,ko01000				Bacteria	1TQ3E@1239,4HAIV@91061,COG0225@1,COG0225@2	NA|NA|NA	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NHHNPPIF_01616	904306.HMPREF9192_0728	1.5e-258	898.3	Bacilli	ascB		3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500		R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000		GT1		Bacteria	1TP19@1239,4HA1W@91061,COG2723@1,COG2723@2	NA|NA|NA	G	Belongs to the glycosyl hydrolase 1 family
NHHNPPIF_01617	1046629.Ssal_00409	1.4e-47	195.3	Bacilli	gatC		6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100		R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029			iAF987.Gmet_0076	Bacteria	1VEK3@1239,4HNNA@91061,COG0721@1,COG0721@2	NA|NA|NA	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHHNPPIF_01618	264199.stu1626	1.6e-269	934.9	Bacilli	gatA		6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100		R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029				Bacteria	1TP0C@1239,4HBAZ@91061,COG0154@1,COG0154@2	NA|NA|NA	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NHHNPPIF_01619	322159.STER_1590	5.1e-273	946.4	Bacilli	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.12,6.3.5.6,6.3.5.7	ko:K01876,ko:K02434	ko00970,ko01100,map00970,map01100	M00359,M00360	R03905,R04212,R05577	RC00010,RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029				Bacteria	1TPG3@1239,4HAFB@91061,COG0064@1,COG0064@2	NA|NA|NA	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHHNPPIF_01620	264199.stu1624	2.1e-64	251.5	Firmicutes													Bacteria	1VBNR@1239,2B9ZC@1,323D0@2	NA|NA|NA		
NHHNPPIF_01621	322159.STER_1587	4.5e-80	303.9	Bacilli	yicL												Bacteria	1TR6G@1239,4HAMD@91061,COG0697@1,COG0697@2	NA|NA|NA	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NHHNPPIF_01622	264199.stu1623	4.7e-62	243.8	Bacilli	yicL												Bacteria	1TR6G@1239,4HAMD@91061,COG0697@1,COG0697@2	NA|NA|NA	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NHHNPPIF_01623	264199.stu1622	1.8e-98	365.2	Bacilli	yqeG			ko:K07015					ko00000				Bacteria	1V6KM@1239,4HGAV@91061,COG2179@1,COG2179@2	NA|NA|NA	S	hydrolase of the HAD superfamily
NHHNPPIF_01624	322159.STER_1585	7.1e-214	749.6	Bacilli	yqeH	GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113		ko:K06948					ko00000,ko03009				Bacteria	1TPM2@1239,4HAAF@91061,COG1161@1,COG1161@2	NA|NA|NA	S	in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NHHNPPIF_01625	264199.stu1620	3.5e-49	200.7	Bacilli	yhbY	GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275		ko:K07574					ko00000,ko03009				Bacteria	1VEGM@1239,4HKC7@91061,COG1534@1,COG1534@2	NA|NA|NA	J	RNA-binding protein
NHHNPPIF_01626	264199.stu1619	1.7e-116	425.2	Bacilli	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18,3.6.1.55	ko:K00969,ko:K03574	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400				Bacteria	1V3SK@1239,4HGXK@91061,COG1057@1,COG1057@2	NA|NA|NA	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NHHNPPIF_01627	264199.stu1618	4e-107	394.0	Bacilli	nadD		2.7.6.3,2.7.7.18	ko:K00950,ko:K00969,ko:K06950	ko00760,ko00790,ko01100,map00760,map00790,map01100	M00115,M00126,M00841	R00137,R03005,R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	1V6Y1@1239,4HHRY@91061,COG1713@1,COG1713@2	NA|NA|NA	H	HD superfamily hydrolase involved in NAD metabolism
NHHNPPIF_01628	322159.STER_1581	6e-58	229.9	Bacilli	rsfS	GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113		ko:K09710					ko00000,ko03009				Bacteria	1VA2Z@1239,4HKEJ@91061,COG0799@1,COG0799@2	NA|NA|NA	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NHHNPPIF_01629	322159.STER_1580	2e-140	505.0	Bacilli	yqeM												Bacteria	1V24K@1239,4HDFY@91061,COG0500@1,COG2226@2	NA|NA|NA	Q	Methyltransferase domain protein
NHHNPPIF_01630	322159.STER_1579	1.9e-200	704.9	Bacilli	ylbM												Bacteria	1TPP2@1239,4HAZJ@91061,COG1323@1,COG1323@2	NA|NA|NA	S	Belongs to the UPF0348 family
NHHNPPIF_01631	264199.stu1614	0.0	1320.8	Bacilli	clpL			ko:K04086					ko00000,ko03110				Bacteria	1TRHP@1239,4HAHZ@91061,COG0542@1,COG0542@2	NA|NA|NA	O	ATP-dependent Clp protease ATP-binding subunit
NHHNPPIF_01632	525379.HMPREF0819_1358	9.8e-19	98.6	Bacilli													Bacteria	1VENK@1239,4HNKV@91061,COG2261@1,COG2261@2	NA|NA|NA	S	Membrane
NHHNPPIF_01633	322159.STER_1960	1.7e-99	368.6	Bacilli													Bacteria	1VK2R@1239,2ED8H@1,33752@2,4HQ99@91061	NA|NA|NA		
NHHNPPIF_01634	264199.stu1984	1.8e-23	114.4	Bacteria													Bacteria	COG5547@1,COG5547@2	NA|NA|NA	S	Small integral membrane protein
NHHNPPIF_01635	264199.stu1986	6.5e-83	313.5	Bacteria													Bacteria	COG1302@1,COG1302@2	NA|NA|NA	M	Protein conserved in bacteria
NHHNPPIF_01636	264199.stu1987	9.2e-11	72.4	Bacteria													Bacteria	COG3237@1,COG3237@2	NA|NA|NA	K	CsbD-like
NHHNPPIF_01637	888821.HMPREF9394_0461	6.7e-125	454.1	Bacilli	gltT			ko:K03309,ko:K11102					ko00000,ko02000	2.A.23,2.A.23.1.1,2.A.23.1.2			Bacteria	1TPME@1239,4H9T7@91061,COG1301@1,COG1301@2	NA|NA|NA	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NHHNPPIF_01638	1005705.HMPREF9967_1422	1.4e-135	489.2	Streptococcus infantis													Bacteria	1TSHN@1239,43FXH@68892,4HBFG@91061,COG0189@1,COG0189@2	NA|NA|NA	HJ	the current gene model (or a revised gene model) may contain a frame shift
NHHNPPIF_01639	525379.HMPREF0819_1358	9.8e-19	98.6	Bacilli													Bacteria	1VENK@1239,4HNKV@91061,COG2261@1,COG2261@2	NA|NA|NA	S	Membrane
NHHNPPIF_01640	322159.STER_1960	1.7e-99	368.6	Bacilli													Bacteria	1VK2R@1239,2ED8H@1,33752@2,4HQ99@91061	NA|NA|NA		
NHHNPPIF_01641	264199.stu1984	1.8e-23	114.4	Bacteria													Bacteria	COG5547@1,COG5547@2	NA|NA|NA	S	Small integral membrane protein
NHHNPPIF_01642	264199.stu1986	6.5e-83	313.5	Bacteria													Bacteria	COG1302@1,COG1302@2	NA|NA|NA	M	Protein conserved in bacteria
NHHNPPIF_01643	264199.stu1987	9.2e-11	72.4	Bacteria													Bacteria	COG3237@1,COG3237@2	NA|NA|NA	K	CsbD-like
NHHNPPIF_01644	1046629.Ssal_00038	1.1e-107	396.0	Bacilli	nudL	GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818											Bacteria	1V6SF@1239,4HG46@91061,COG0494@1,COG0494@2	NA|NA|NA	L	hydrolase
NHHNPPIF_01645	1403946.Q615_SPAC00123G0004	3.1e-44	184.1	Bacilli				ko:K07483					ko00000				Bacteria	1V9ZX@1239,4HKN9@91061,COG2963@1,COG2963@2	NA|NA|NA	L	COG2963 Transposase and inactivated derivatives
NHHNPPIF_01646	1403946.Q615_SPAC00123G0003	5.9e-62	243.4	Bacilli													Bacteria	1TPEH@1239,4HCHG@91061,COG2801@1,COG2801@2	NA|NA|NA	L	Transposase and inactivated derivatives
NHHNPPIF_01647	1123299.AUKZ01000032_gene1329	1.5e-39	168.3	Bacteria													Bacteria	COG2801@1,COG2801@2	NA|NA|NA	L	transposition
NHHNPPIF_01648	862970.SAIN_0151	2.2e-17	95.9	Streptococcus anginosus group													Bacteria	1TVY9@1239,29H5Y@1,3043H@2,42EEJ@671232,4I4K4@91061	NA|NA|NA		
NHHNPPIF_01649	1035184.HMPREF1042_2341	8.6e-41	174.1	Streptococcus anginosus group													Bacteria	1TW0G@1239,2DIU0@1,3044E@2,42EHD@671232,4I4P6@91061	NA|NA|NA		
NHHNPPIF_01650	1035184.HMPREF1042_2340	1.8e-28	133.3	Streptococcus anginosus group				ko:K06236	ko04151,ko04510,ko04512,ko04611,ko04926,ko04933,ko04974,ko05146,ko05165,map04151,map04510,map04512,map04611,map04926,map04933,map04974,map05146,map05165				ko00000,ko00001,ko00536,ko04516				Bacteria	1UMUJ@1239,42EFA@671232,4IU0F@91061,COG3468@1,COG3468@2	NA|NA|NA	MU	outer membrane autotransporter barrel domain protein
NHHNPPIF_01651	1035184.HMPREF1042_2339	4.7e-62	244.2	Streptococcus anginosus group													Bacteria	1VIW8@1239,2EDAG@1,3376W@2,42EGT@671232,4HQS8@91061	NA|NA|NA		
NHHNPPIF_01652	862969.SCI_0190	2.6e-311	1073.9	Streptococcus anginosus group				ko:K03205	ko03070,map03070	M00333			ko00000,ko00001,ko00002,ko02044	3.A.7			Bacteria	1TPCF@1239,42E83@671232,4HF20@91061,COG3505@1,COG3505@2	NA|NA|NA	U	Type IV secretory system Conjugative DNA transfer
NHHNPPIF_01653	1035184.HMPREF1042_2341	8.6e-41	174.1	Streptococcus anginosus group													Bacteria	1TW0G@1239,2DIU0@1,3044E@2,42EHD@671232,4I4P6@91061	NA|NA|NA		
NHHNPPIF_01654	1035184.HMPREF1042_2340	3e-29	136.0	Streptococcus anginosus group				ko:K06236	ko04151,ko04510,ko04512,ko04611,ko04926,ko04933,ko04974,ko05146,ko05165,map04151,map04510,map04512,map04611,map04926,map04933,map04974,map05146,map05165				ko00000,ko00001,ko00536,ko04516				Bacteria	1UMUJ@1239,42EFA@671232,4IU0F@91061,COG3468@1,COG3468@2	NA|NA|NA	MU	outer membrane autotransporter barrel domain protein
NHHNPPIF_01655	1035184.HMPREF1042_2339	4.7e-62	244.2	Streptococcus anginosus group													Bacteria	1VIW8@1239,2EDAG@1,3376W@2,42EGT@671232,4HQS8@91061	NA|NA|NA		
NHHNPPIF_01656	862969.SCI_0190	2.6e-311	1073.9	Streptococcus anginosus group				ko:K03205	ko03070,map03070	M00333			ko00000,ko00001,ko00002,ko02044	3.A.7			Bacteria	1TPCF@1239,42E83@671232,4HF20@91061,COG3505@1,COG3505@2	NA|NA|NA	U	Type IV secretory system Conjugative DNA transfer
NHHNPPIF_01657	1035184.HMPREF1042_2341	3.2e-66	258.8	Streptococcus anginosus group													Bacteria	1TW0G@1239,2DIU0@1,3044E@2,42EHD@671232,4I4P6@91061	NA|NA|NA		
NHHNPPIF_01659	862969.SCI_0185	1.1e-104	386.0	Bacilli													Bacteria	1VDM9@1239,2DNFF@1,32X8K@2,4HNCS@91061	NA|NA|NA		
NHHNPPIF_01660	873447.SPB_0377	0.0	1174.5	Bacilli													Bacteria	1VPFZ@1239,4HFGV@91061,COG3942@1,COG3942@2	NA|NA|NA	M	CHAP domain protein
NHHNPPIF_01661	1035184.HMPREF1042_2347	0.0	1408.3	Bacilli													Bacteria	1TPDR@1239,4HC47@91061,COG3451@1,COG3451@2	NA|NA|NA	U	Psort location Cytoplasmic, score
NHHNPPIF_01662	1000570.HMPREF9966_1913	5e-12	77.4	Streptococcus anginosus group													Bacteria	1TVYC@1239,2DITG@1,3043I@2,42EER@671232,4I4K8@91061	NA|NA|NA	S	PrgI family protein
NHHNPPIF_01664	1035184.HMPREF1042_2350	3e-104	384.8	Streptococcus anginosus group													Bacteria	1VY42@1239,2EFFF@1,33986@2,42EEK@671232,4HMPN@91061	NA|NA|NA		
NHHNPPIF_01666	1035184.HMPREF1042_2352	4e-40	170.6	Bacteria													Bacteria	COG4443@1,COG4443@2	NA|NA|NA	S	Transcriptional Coactivator p15 (PC4)
NHHNPPIF_01667	1035184.HMPREF1042_2353	1.7e-38	165.2	Streptococcus anginosus group													Bacteria	1TW11@1239,2DIUA@1,3044T@2,42EI4@671232,4I4PX@91061	NA|NA|NA		
NHHNPPIF_01668	862969.SCI_0175	8.2e-96	357.1	Streptococcus anginosus group	repA												Bacteria	1VHQA@1239,2DP1C@1,3304N@2,42DYE@671232,4HPY6@91061	NA|NA|NA	S	Replication initiator protein A (RepA) N-terminus
NHHNPPIF_01670	322159.STER_0492	8.6e-167	593.2	Bacteria	prsA		3.1.3.16,5.2.1.8	ko:K01802,ko:K03769,ko:K07533,ko:K20074					ko00000,ko01000,ko01009,ko03110				Bacteria	COG0760@1,COG0760@2	NA|NA|NA	O	peptidyl-prolyl cis-trans isomerase activity
NHHNPPIF_01671	264199.stu0455	7.1e-127	459.9	Bacilli	yrrM		2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000				Bacteria	1UF4M@1239,4HE9E@91061,COG4122@1,COG4122@2	NA|NA|NA	S	O-Methyltransferase
NHHNPPIF_01672	322159.STER_0489	0.0	1199.9	Bacilli	pepF	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564		ko:K08602					ko00000,ko01000,ko01002				Bacteria	1TP4P@1239,4HA7X@91061,COG1164@1,COG1164@2	NA|NA|NA	E	oligoendopeptidase F
NHHNPPIF_01673	322159.STER_0488	1.4e-186	658.7	Bacilli	coiA		3.6.4.12	ko:K03657,ko:K06198	ko03420,ko03430,map03420,map03430				ko00000,ko00001,ko01000,ko03400				Bacteria	1TRGD@1239,4HFP5@91061,COG4469@1,COG4469@2	NA|NA|NA	S	Competence protein
NHHNPPIF_01674	904306.HMPREF9192_0361	3.5e-163	580.9	Bacilli													Bacteria	1V53I@1239,4HIEU@91061,COG0583@1,COG0583@2	NA|NA|NA	K	transcriptional regulator (lysR family)
NHHNPPIF_01675	264199.stu0451	0.0	1342.8	Bacilli	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10,6.1.1.20	ko:K01874,ko:K01890,ko:K06878	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R03660,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1TPA1@1239,4H9VC@91061,COG0073@1,COG0073@2,COG0143@1,COG0143@2	NA|NA|NA	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NHHNPPIF_01679	322159.STER_0480	1e-190	672.5	Bacilli	phoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K06217					ko00000				Bacteria	1TP35@1239,4HBD5@91061,COG1702@1,COG1702@2	NA|NA|NA	T	phosphate starvation-inducible protein PhoH
NHHNPPIF_01680	264199.stu0446	1.7e-60	238.8	Bacilli	rlpA			ko:K03642					ko00000				Bacteria	1V61Q@1239,4HHT0@91061,COG1388@1,COG1388@2	NA|NA|NA	M	LysM domain protein
NHHNPPIF_01681	322159.STER_0042	4.1e-59	233.8	Bacilli	usp		3.5.1.28	ko:K21471,ko:K22409					ko00000,ko01000,ko01002,ko01011		CBM50		Bacteria	1VCXB@1239,4IS6H@91061,COG3883@1,COG3883@2,COG3942@1,COG3942@2	NA|NA|NA	S	CHAP domain
NHHNPPIF_01682	264199.stu0296	1.8e-153	548.5	Bacteria				ko:K02030		M00236			ko00000,ko00002,ko02000	3.A.1.3			Bacteria	COG0834@1,COG0834@2	NA|NA|NA	ET	amino acid transport
NHHNPPIF_01683	563038.HMPREF0851_01449	1.6e-27	129.0	Bacilli													Bacteria	1W3A8@1239,2DEIC@1,2ZN3X@2,4HZMP@91061	NA|NA|NA		
NHHNPPIF_01684	264199.stu1596	0.0	1476.1	Bacilli	ctpE			ko:K12952					ko00000,ko01000	3.A.3.23			Bacteria	1TPF5@1239,4H9ZI@91061,COG0474@1,COG0474@2	NA|NA|NA	P	E1-E2 ATPase
NHHNPPIF_01685	1046629.Ssal_00451	2.7e-55	221.1	Bacilli													Bacteria	1VCIA@1239,2C4MC@1,32RSW@2,4HKKA@91061	NA|NA|NA		
NHHNPPIF_01686	322159.STER_1555	1.8e-41	174.9	Bacteria	pchB		2.5.1.19,4.2.1.10,4.2.99.21,5.4.99.5	ko:K00800,ko:K03785,ko:K04092,ko:K04782	ko00400,ko01053,ko01100,ko01110,ko01130,ko01230,map00400,map01053,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R03084,R03460,R06602	RC00350,RC00848,RC01549,RC02148,RC03116	ko00000,ko00001,ko00002,ko01000				Bacteria	COG1605@1,COG1605@2	NA|NA|NA	E	Chorismate mutase
NHHNPPIF_01687	264199.stu1593	2e-255	887.9	Bacilli	trpE	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQAP@1239,4HB31@91061,COG0147@1,COG0147@2	NA|NA|NA	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NHHNPPIF_01688	322159.STER_1553	1.2e-105	389.0	Bacilli	trpG		2.4.2.18,2.6.1.85,4.1.3.27	ko:K00766,ko:K01658,ko:K01664,ko:K13497	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01073,R01716	RC00010,RC00440,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000				Bacteria	1V4RM@1239,4HHD8@91061,COG0512@1,COG0512@2	NA|NA|NA	EH	anthranilate
NHHNPPIF_01689	322159.STER_1552	7.8e-180	636.3	Bacilli	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP8U@1239,4H9KQ@91061,COG0547@1,COG0547@2	NA|NA|NA	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NHHNPPIF_01690	322159.STER_1551	8.5e-134	483.0	Bacilli	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48,5.3.1.24	ko:K01609,ko:K01817,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000				Bacteria	1TR94@1239,4HG9K@91061,COG0134@1,COG0134@2	NA|NA|NA	E	Belongs to the TrpC family
NHHNPPIF_01691	322159.STER_1550	5.5e-101	373.6	Bacilli	trpF	GO:0000162,GO:0003674,GO:0003824,GO:0004425,GO:0004640,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.48,4.2.1.160,4.2.1.20,5.3.1.24	ko:K01696,ko:K01817,ko:K13498,ko:K22100	ko00260,ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map00790,map01100,map01110,map01130,map01230	M00023,M00840	R00674,R02340,R02722,R03508,R03509,R11072	RC00209,RC00210,RC00700,RC00701,RC00944,RC00945,RC02868,RC03343	ko00000,ko00001,ko00002,ko01000			iJN678.trpF,iPC815.YPO2205,iSBO_1134.SBO_1804,iSDY_1059.SDY_1330	Bacteria	1V6Y0@1239,4HK18@91061,COG0135@1,COG0135@2	NA|NA|NA	E	belongs to the TrpF family
NHHNPPIF_01692	322159.STER_1549	3.8e-229	800.4	Bacilli	trpB	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20,5.3.1.24	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03509	RC00209,RC00210,RC00700,RC00701,RC00945,RC02868	ko00000,ko00001,ko00002,ko01000			iYO844.BSU22640	Bacteria	1TPI3@1239,4H9WC@91061,COG0133@1,COG0133@2	NA|NA|NA	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NHHNPPIF_01693	264199.stu1587	6e-143	513.5	Bacilli	trpA		4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPXA@1239,4HFQ8@91061,COG0159@1,COG0159@2	NA|NA|NA	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NHHNPPIF_01694	322159.STER_1547	2.7e-73	281.2	Bacilli	copY												Bacteria	1VA7Q@1239,4HKGF@91061,COG3682@1,COG3682@2	NA|NA|NA	K	Copper transport repressor, CopY TcrY family
NHHNPPIF_01695	322159.STER_1546	0.0	1315.4	Bacilli	copA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016		R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5			Bacteria	1TP5S@1239,4HAI0@91061,COG2217@1,COG2217@2	NA|NA|NA	P	P-type ATPase
NHHNPPIF_01696	264199.stu1584	4.7e-31	139.8	Bacilli	copZ	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0006811,GO:0006812,GO:0006873,GO:0006875,GO:0008150,GO:0009987,GO:0019725,GO:0030001,GO:0030003,GO:0042592,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771	2.7.7.77	ko:K03752,ko:K07213,ko:K08364	ko00790,ko01100,ko04978,map00790,map01100,map04978		R11581		ko00000,ko00001,ko01000,ko02000	1.A.72.1			Bacteria	1VK5F@1239,4HR1Z@91061,COG2608@1,COG2608@2	NA|NA|NA	P	Heavy metal-associated domain protein
NHHNPPIF_01697	322159.STER_1544	1.7e-193	681.8	Bacilli	ddl		6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502		R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011				Bacteria	1TP2Y@1239,4H9KB@91061,COG1181@1,COG1181@2	NA|NA|NA	F	Belongs to the D-alanine--D-alanine ligase family
NHHNPPIF_01698	264199.stu1582	3.9e-114	417.5	Bacilli	papP			ko:K02029		M00236			ko00000,ko00002,ko02000	3.A.1.3			Bacteria	1TRU3@1239,4HGE1@91061,COG0765@1,COG0765@2	NA|NA|NA	P	ABC transporter (Permease
NHHNPPIF_01699	1046629.Ssal_00474	3e-106	391.3	Bacilli				ko:K02029		M00236			ko00000,ko00002,ko02000	3.A.1.3			Bacteria	1TR7R@1239,4HGVA@91061,COG0765@1,COG0765@2	NA|NA|NA	P	ABC transporter (Permease
NHHNPPIF_01700	264199.stu1580	1.7e-134	485.3	Bacilli	glnQ		3.6.3.21	ko:K02028		M00236			ko00000,ko00002,ko01000,ko02000	3.A.1.3			Bacteria	1TNYD@1239,4HDK7@91061,COG1126@1,COG1126@2	NA|NA|NA	E	abc transporter atp-binding protein
NHHNPPIF_01701	322159.STER_1539	1.1e-155	555.8	Bacilli	cjaA			ko:K02030		M00236			ko00000,ko00002,ko02000	3.A.1.3			Bacteria	1TT11@1239,4HFBQ@91061,COG0834@1,COG0834@2	NA|NA|NA	ET	ABC transporter substrate-binding protein
NHHNPPIF_01705	322159.STER_1534	1.7e-257	894.8	Bacilli	murF		6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502		R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011				Bacteria	1VT78@1239,4HACR@91061,COG0770@1,COG0770@2	NA|NA|NA	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NHHNPPIF_01706	322159.STER_1533	7.1e-121	439.9	Bacteria	ywaF												Bacteria	COG5522@1,COG5522@2	NA|NA|NA	S	Integral membrane protein (intg_mem_TP0381)
NHHNPPIF_01707	322159.STER_1532	3.1e-300	1036.9	Bacilli	prfC	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576		ko:K02837,ko:K07133					ko00000,ko03012				Bacteria	1TPYT@1239,4HADS@91061,COG4108@1,COG4108@2	NA|NA|NA	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NHHNPPIF_01708	264199.stu1598	1.2e-43	182.2	Bacilli	yaaK			ko:K09747					ko00000				Bacteria	1VA1S@1239,4HKH3@91061,COG0718@1,COG0718@2	NA|NA|NA	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NHHNPPIF_01709	264199.stu1599	5.1e-47	193.4	Bacilli													Bacteria	1VFYX@1239,4HNKT@91061,COG2963@1,COG2963@2	NA|NA|NA	L	transposase activity
NHHNPPIF_01710	904306.HMPREF9192_0780	6e-121	440.3	Bacilli													Bacteria	1UZ0H@1239,4HGGU@91061,COG0789@1,COG0789@2	NA|NA|NA	K	transcriptional regulator, MerR family
NHHNPPIF_01711	264199.stu1601	1.3e-102	379.0	Bacilli	dnaQ		2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1V8EQ@1239,4HJYT@91061,COG0847@1,COG0847@2	NA|NA|NA	L	DNA polymerase III
NHHNPPIF_01712	264199.stu1602	9.1e-42	176.8	Bacilli	WQ51_02910												Bacteria	1VNC1@1239,2EHT6@1,33BIW@2,4HRJ5@91061	NA|NA|NA	S	Protein of unknown function, DUF536
NHHNPPIF_01713	264199.stu1603	4.8e-63	246.9	Bacilli	XK27_02560			ko:K02612	ko00360,ko01120,map00360,map01120		R09838	RC02690	ko00000,ko00001				Bacteria	1VX9Z@1239,4HXCM@91061,COG2151@1,COG2151@2	NA|NA|NA	S	cog cog2151
NHHNPPIF_01714	264199.stu1604	0.0	1133.6	Bacilli	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP1R@1239,4H9ZG@91061,COG0129@1,COG0129@2	NA|NA|NA	E	Belongs to the IlvD Edd family
NHHNPPIF_01715	264199.stu1605	3.8e-226	790.4	Bacilli	ytfP			ko:K07007					ko00000				Bacteria	1TQ6E@1239,4HAAT@91061,COG2081@1,COG2081@2	NA|NA|NA	S	Flavoprotein
NHHNPPIF_01717	264199.stu1606	3.4e-120	437.6	Bacilli	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.297,2.1.1.33	ko:K02493,ko:K03439			R10806	RC00003,RC03279	ko00000,ko01000,ko03012,ko03016				Bacteria	1TQCA@1239,4HC08@91061,COG0220@1,COG0220@2	NA|NA|NA	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NHHNPPIF_01718	264199.stu1607	1.2e-151	542.3	Bacilli	ytmP		2.7.1.89	ko:K07251	ko00730,ko01100,map00730,map01100		R02134	RC00002,RC00017	ko00000,ko00001,ko01000				Bacteria	1UMFY@1239,4HBF9@91061,COG0510@1,COG0510@2	NA|NA|NA	M	Phosphotransferase
NHHNPPIF_01719	322159.STER_1571	4.3e-181	640.6	Bacilli	ecsB			ko:K01992		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1V1VG@1239,4HG1K@91061,COG4473@1,COG4473@2	NA|NA|NA	U	ABC transporter
NHHNPPIF_01720	264199.stu1609	1.1e-130	472.6	Bacilli	ecsA			ko:K01990		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1TQIH@1239,4HA2B@91061,COG1131@1,COG1131@2	NA|NA|NA	V	abc transporter atp-binding protein
NHHNPPIF_01721	322159.STER_1573	1.1e-69	269.2	Bacilli	hit			ko:K02503					ko00000,ko04147				Bacteria	1V9ZJ@1239,4HIG2@91061,COG0537@1,COG0537@2	NA|NA|NA	FG	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NHHNPPIF_01722	1000588.HMPREF9965_1970	1.9e-09	68.6	Streptococcus mitis													Bacteria	1U4H8@1239,2DKCI@1,2TPVV@28037,30963@2,4IE92@91061	NA|NA|NA		
NHHNPPIF_01724	435842.HMPREF0848_01249	1.1e-19	102.8	Bacilli													Bacteria	1VI51@1239,2E9BR@1,333JH@2,4HQRQ@91061	NA|NA|NA		
NHHNPPIF_01725	1008453.HMPREF9957_0290	6.3e-07	60.8	Streptococcus mitis													Bacteria	1UD5G@1239,2DIAX@1,2TNYQ@28037,302KA@2,4IE19@91061	NA|NA|NA		
NHHNPPIF_01726	862967.SIR_1563	4.5e-14	83.6	Streptococcus anginosus group													Bacteria	1V6MD@1239,2BH95@1,32BAK@2,42DVS@671232,4I42D@91061	NA|NA|NA		
NHHNPPIF_01727	1046629.Ssal_02110	3.2e-33	147.5	Bacilli													Bacteria	1TRSF@1239,4HDM3@91061,COG2826@1,COG2826@2	NA|NA|NA	L	PFAM Integrase, catalytic core
NHHNPPIF_01728	264199.stu1898	9.3e-72	276.2	Bacilli													Bacteria	1TRSF@1239,4HDM3@91061,COG2826@1,COG2826@2	NA|NA|NA	L	PFAM Integrase, catalytic core
NHHNPPIF_01729	264199.stu1907	3.3e-62	244.2	Bacilli	rplQ	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02879,ko:K16193	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V6JQ@1239,4HGX2@91061,COG0203@1,COG0203@2	NA|NA|NA	J	ribosomal protein l17
NHHNPPIF_01730	264199.stu1908	6.2e-171	606.7	Bacilli	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400				Bacteria	1TPR8@1239,4H9R1@91061,COG0202@1,COG0202@2	NA|NA|NA	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHHNPPIF_01731	1214166.ALLG01000006_gene1437	9.6e-62	242.7	Streptococcus suis	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02948	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V3IK@1239,1WTHI@1307,4HH2T@91061,COG0100@1,COG0100@2	NA|NA|NA	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NHHNPPIF_01732	1046629.Ssal_00108	4e-57	227.3	Bacilli	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02952	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V3JH@1239,4HGX6@91061,COG0099@1,COG0099@2	NA|NA|NA	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NHHNPPIF_01733	1123301.KB904201_gene1724	6e-15	85.5	Bacteria	rpmJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02919	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	COG0257@1,COG0257@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL36 family
NHHNPPIF_01734	1123298.KB904065_gene2021	5.9e-32	142.9	Bacilli	infA	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009986,GO:0016020,GO:0030246,GO:0030247,GO:0030312,GO:0040007,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071944,GO:2001065		ko:K02518					ko00000,ko03012				Bacteria	1V9ZK@1239,4HKF4@91061,COG0361@1,COG0361@2	NA|NA|NA	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NHHNPPIF_01735	264199.stu1913	9.2e-121	439.5	Bacilli	adk	GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147			iHN637.CLJU_RS20110	Bacteria	1TP27@1239,4HA89@91061,COG0563@1,COG0563@2	NA|NA|NA	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NHHNPPIF_01736	322159.STER_1887	3.6e-201	707.6	Bacilli	secY	GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0040007,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680		ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	3.A.5			Bacteria	1TPHB@1239,4HAWH@91061,COG0201@1,COG0201@2	NA|NA|NA	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NHHNPPIF_01737	322159.STER_1888	1.3e-57	229.2	Bacilli	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02876	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V3KE@1239,4HFPW@91061,COG0200@1,COG0200@2	NA|NA|NA	J	binds to the 23S rRNA
NHHNPPIF_01738	264199.stu1916	2.5e-23	114.0	Bacilli	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904		ko:K02907	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1VEG4@1239,4HNHF@91061,COG1841@1,COG1841@2	NA|NA|NA	J	ribosomal protein l30
NHHNPPIF_01739	264199.stu1917	1.7e-79	302.0	Bacilli	rpsE	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904		ko:K02988	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V1B1@1239,4HFN4@91061,COG0098@1,COG0098@2	NA|NA|NA	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NHHNPPIF_01740	264199.stu1918	1.9e-56	224.9	Bacilli	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02881	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V6DM@1239,4HIGF@91061,COG0256@1,COG0256@2	NA|NA|NA	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NHHNPPIF_01741	264199.stu1919	2.3e-93	348.2	Bacilli	rplF	GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02933	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V1FC@1239,4HFQD@91061,COG0097@1,COG0097@2	NA|NA|NA	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NHHNPPIF_01742	1123304.AQYA01000030_gene1163	1.6e-67	261.9	Bacilli	rpsH	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010608,GO:0015935,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031329,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043487,GO:0043488,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903311,GO:1990904		ko:K02994	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V3KK@1239,4HH32@91061,COG0096@1,COG0096@2	NA|NA|NA	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NHHNPPIF_01743	264199.stu1921	1.5e-28	131.3	Bacilli	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02954	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1VEF6@1239,4HNKX@91061,COG0199@1,COG0199@2	NA|NA|NA	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NHHNPPIF_01744	264199.stu1922	1.2e-94	352.4	Bacilli	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02931	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1TPE0@1239,4HBAX@91061,COG0094@1,COG0094@2	NA|NA|NA	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NHHNPPIF_01745	264199.stu1923	1.1e-47	195.7	Bacilli	rplX	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02895	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V9ZQ@1239,4HKH9@91061,COG0198@1,COG0198@2	NA|NA|NA	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NHHNPPIF_01746	264199.stu1924	1.1e-59	235.7	Bacilli	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02874	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V3N0@1239,4HGYR@91061,COG0093@1,COG0093@2	NA|NA|NA	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NHHNPPIF_01747	1046629.Ssal_00093	6e-39	166.4	Bacilli	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02961	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V9YC@1239,4HKDN@91061,COG0186@1,COG0186@2	NA|NA|NA	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NHHNPPIF_01748	264199.stu1926	2.7e-26	124.0	Bacilli	rpmC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02904	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1VEME@1239,4HNUP@91061,COG0255@1,COG0255@2	NA|NA|NA	J	Belongs to the universal ribosomal protein uL29 family
NHHNPPIF_01749	322159.STER_1900	1e-69	269.2	Bacilli	rplP	GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02878	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V1AY@1239,4HFPN@91061,COG0197@1,COG0197@2	NA|NA|NA	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NHHNPPIF_01750	264199.stu1928	7.5e-115	419.9	Bacilli	rpsC	GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02982	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1TPCP@1239,4HAUR@91061,COG0092@1,COG0092@2	NA|NA|NA	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NHHNPPIF_01751	1046629.Ssal_00089	7.3e-53	213.0	Bacilli	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02890	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V6PU@1239,4HIK2@91061,COG0091@1,COG0091@2	NA|NA|NA	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NHHNPPIF_01752	322159.STER_1903	4.9e-47	193.4	Bacilli	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02965	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V6CX@1239,4HIG0@91061,COG0185@1,COG0185@2	NA|NA|NA	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NHHNPPIF_01753	264199.stu1931	2.6e-152	544.7	Bacilli	rplB	GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02886	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1TP9X@1239,4HAE8@91061,COG0090@1,COG0090@2	NA|NA|NA	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NHHNPPIF_01754	264199.stu1932	2.4e-44	184.5	Bacilli	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02892	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1VA4W@1239,4HKCV@91061,COG0089@1,COG0089@2	NA|NA|NA	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NHHNPPIF_01755	1046629.Ssal_00085	7.4e-104	383.3	Bacilli	rplD	GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030312,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141		ko:K02926,ko:K16193	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1TPGW@1239,4HB01@91061,COG0088@1,COG0088@2	NA|NA|NA	J	Forms part of the polypeptide exit tunnel
NHHNPPIF_01756	264199.stu1934	1.8e-110	405.2	Bacilli	rplC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234		ko:K02906	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1TPFT@1239,4HAEN@91061,COG0087@1,COG0087@2	NA|NA|NA	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NHHNPPIF_01757	1046629.Ssal_00083	2.9e-48	197.6	Bacilli	rpsJ	GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141		ko:K02946	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V6C9@1239,4HIKH@91061,COG0051@1,COG0051@2	NA|NA|NA	J	Involved in the binding of tRNA to the ribosomes
NHHNPPIF_01758	264199.stu1936	6.6e-187	659.8	Bacilli	ruvB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	3.6.4.12	ko:K03551	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1TR47@1239,4HBMW@91061,COG2255@1,COG2255@2	NA|NA|NA	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NHHNPPIF_01759	264199.stu1937	0.0	1156.4	Bacilli	XK27_09800												Bacteria	1U6DU@1239,4H9XT@91061,COG1835@1,COG1835@2	NA|NA|NA	I	Acyltransferase
NHHNPPIF_01760	264199.stu1938	1.7e-35	155.6	Firmicutes	XK27_09805												Bacteria	1TRNW@1239,COG4642@1,COG4642@2	NA|NA|NA	S	MORN repeat protein
NHHNPPIF_01761	264199.stu1939	5.2e-80	303.5	Bacilli	ptpA		3.1.3.48	ko:K01104,ko:K20945	ko05111,map05111				ko00000,ko00001,ko01000				Bacteria	1V6SG@1239,4HIZN@91061,COG0394@1,COG0394@2	NA|NA|NA	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NHHNPPIF_01762	1046629.Ssal_02110	3.2e-33	147.5	Bacilli													Bacteria	1TRSF@1239,4HDM3@91061,COG2826@1,COG2826@2	NA|NA|NA	L	PFAM Integrase, catalytic core
NHHNPPIF_01763	264199.stu1898	9.3e-72	276.2	Bacilli													Bacteria	1TRSF@1239,4HDM3@91061,COG2826@1,COG2826@2	NA|NA|NA	L	PFAM Integrase, catalytic core
NHHNPPIF_01764	1151292.QEW_2309	2.4e-199	701.4	Peptostreptococcaceae													Bacteria	1TPCB@1239,2485Y@186801,25R4G@186804,COG0582@1,COG0582@2	NA|NA|NA	L	Belongs to the 'phage' integrase family
NHHNPPIF_01765	1121115.AXVN01000025_gene941	4.4e-29	133.3	Blautia													Bacteria	1VABI@1239,24MZT@186801,2CCB2@1,32S7G@2,3Y0H0@572511	NA|NA|NA	S	Psort location Cytoplasmic, score 8.87
NHHNPPIF_01766	272563.CD630_22240	4.1e-31	140.2	Firmicutes													Bacteria	1VJQN@1239,2AJW5@1,337FZ@2	NA|NA|NA	S	Helix-turn-helix domain
NHHNPPIF_01767	169963.lmo1099	2.6e-53	214.5	Listeriaceae	phyR			ko:K03088					ko00000,ko03021				Bacteria	1W79P@1239,26MZ4@186820,4I0N4@91061,COG1595@1,COG1595@2	NA|NA|NA	K	Sigma-70, region 4
NHHNPPIF_01768	169963.lmo1100	0.0	1259.2	Listeriaceae	cadA		3.6.3.3,3.6.3.5	ko:K01534					ko00000,ko01000	3.A.3.6			Bacteria	1TQ07@1239,26JS1@186820,4H9SP@91061,COG2217@1,COG2217@2	NA|NA|NA	P	E1-E2 ATPase
NHHNPPIF_01769	169963.lmo1101	1.4e-63	249.2	Bacilli	lspA		3.4.23.36	ko:K03101	ko03060,map03060				ko00000,ko00001,ko01000,ko01002				Bacteria	1VA9R@1239,4HIR4@91061,COG0597@1,COG0597@2	NA|NA|NA	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NHHNPPIF_01770	169963.lmo1102	1e-46	192.6	Listeriaceae	cadC			ko:K21903					ko00000,ko03000				Bacteria	1VA6G@1239,26M2C@186820,4HJ09@91061,COG0640@1,COG0640@2	NA|NA|NA	K	helix_turn_helix, Arsenical Resistance Operon Repressor
NHHNPPIF_01771	1069533.Sinf_0249	7.6e-154	549.7	Firmicutes													Bacteria	1TRUP@1239,COG2801@1,COG2801@2	NA|NA|NA	L	Integrase core domain protein
NHHNPPIF_01772	1116231.SMA_1992	6.3e-38	162.9	Bacteria				ko:K07483,ko:K07497					ko00000				Bacteria	COG2963@1,COG2963@2	NA|NA|NA	L	transposase activity
NHHNPPIF_01773	883113.HMPREF9708_01392	1.1e-199	702.6	Bacilli													Bacteria	1UI3B@1239,4ISBW@91061,COG0477@1,COG2814@2	NA|NA|NA	EGP	Major facilitator Superfamily
NHHNPPIF_01774	264199.stu0099	1.9e-32	144.8	Bacteria	spaC2			ko:K20484	ko02020,ko02024,map02020,map02024				ko00000,ko00001				Bacteria	COG4403@1,COG4403@2	NA|NA|NA	V	Lanthionine synthetase C family protein
NHHNPPIF_01775	322159.STER_1196	5.4e-197	693.3	Firmicutes													Bacteria	1UEG7@1239,COG3039@1,COG3039@2	NA|NA|NA	L	transposase, IS4 family
NHHNPPIF_01776	1116231.SMA_0302	1.4e-15	87.8	Bacilli	tnp			ko:K07498					ko00000				Bacteria	1UTIC@1239,4HCF1@91061,COG3316@1,COG3316@2	NA|NA|NA	L	DDE domain
NHHNPPIF_01777	1215915.BN193_04215	2.1e-08	63.9	Bacilli													Bacteria	1VJ28@1239,4HQR7@91061,COG3039@1,COG3039@2	NA|NA|NA	L	Transposase
NHHNPPIF_01778	997830.HMPREF1124_1826	1.2e-43	182.2	Firmicutes													Bacteria	1VFJD@1239,2E660@1,330UP@2	NA|NA|NA		
NHHNPPIF_01779	1214166.ALLG01000004_gene435	1.6e-45	188.7	Bacilli													Bacteria	1VFMU@1239,2E59Z@1,33028@2,4HQG9@91061	NA|NA|NA		
NHHNPPIF_01780	1214166.ALLG01000004_gene434	1.6e-206	725.3	Bacilli	uvrX		2.7.7.7	ko:K02346,ko:K03502,ko:K14161					ko00000,ko01000,ko03400				Bacteria	1TP42@1239,4HA1P@91061,COG0389@1,COG0389@2	NA|NA|NA	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHHNPPIF_01781	264199.stu1898	9.3e-72	276.2	Bacilli													Bacteria	1TRSF@1239,4HDM3@91061,COG2826@1,COG2826@2	NA|NA|NA	L	PFAM Integrase, catalytic core
NHHNPPIF_01782	1046629.Ssal_02110	3.2e-33	147.5	Bacilli													Bacteria	1TRSF@1239,4HDM3@91061,COG2826@1,COG2826@2	NA|NA|NA	L	PFAM Integrase, catalytic core
NHHNPPIF_01783	904306.HMPREF9192_1984	3.2e-12	77.4	Bacilli			6.3.2.2	ko:K01919,ko:K06048	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000				Bacteria	1TW3D@1239,4HTV4@91061,COG3572@1,COG3572@2	NA|NA|NA	H	gamma-glutamylcysteine synthetase
NHHNPPIF_01784	1046629.Ssal_00112	7.3e-34	149.4	Bacilli			6.3.2.2	ko:K01919,ko:K06048	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000				Bacteria	1TW3D@1239,4HTV4@91061,COG3572@1,COG3572@2	NA|NA|NA	H	gamma-glutamylcysteine synthetase
NHHNPPIF_01785	264199.stu1900	1.6e-103	382.1	Bacteria			6.3.2.2	ko:K01919,ko:K06048	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000				Bacteria	COG3572@1,COG3572@2	NA|NA|NA	H	ergothioneine biosynthetic process
NHHNPPIF_01787	322159.STER_1876	2.8e-165	587.8	Bacilli	fba		4.1.2.13,4.1.2.29	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568,R05378	RC00438,RC00439,RC00603,RC00604,RC00721	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQ01@1239,4H9ZU@91061,COG0191@1,COG0191@2	NA|NA|NA	G	aldolase
NHHNPPIF_01788	1046629.Ssal_00336	1.9e-13	80.5	Bacteria													Bacteria	COG3464@1,COG3464@2	NA|NA|NA		
NHHNPPIF_01789	264199.stu1451	2.7e-74	284.6	Firmicutes				ko:K07497					ko00000				Bacteria	1TRR6@1239,COG2801@1,COG2801@2	NA|NA|NA	L	PFAM Integrase catalytic region
NHHNPPIF_01790	322159.STER_1416	9.9e-214	749.2	Bacilli	oxlT			ko:K08177					ko00000,ko02000	2.A.1.11			Bacteria	1TPR9@1239,4HB93@91061,COG2223@1,COG2223@2	NA|NA|NA	P	COG0477 Permeases of the major facilitator superfamily
NHHNPPIF_01791	525379.HMPREF0819_1242	1.4e-40	171.8	Bacilli	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575		ko:K03424					ko00000,ko01000				Bacteria	1TNY1@1239,4HA74@91061,COG0084@1,COG0084@2	NA|NA|NA	L	Hydrolase, tatd
NHHNPPIF_01792	264199.stu1447	1.1e-44	185.7	Bacilli	oppF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439			ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1V36J@1239,4HCM4@91061,COG4608@1,COG4608@2	NA|NA|NA	P	Belongs to the ABC transporter superfamily
NHHNPPIF_01793	904306.HMPREF9192_0265	1.5e-12	77.8	Bacteria													Bacteria	COG3464@1,COG3464@2	NA|NA|NA		
NHHNPPIF_01794	322159.STER_1753	1.3e-87	328.9	Bacilli													Bacteria	1VAJG@1239,4HKDZ@91061,COG4129@1,COG4129@2	NA|NA|NA	S	Fusaric acid resistance protein-like
NHHNPPIF_01795	322159.STER_1752	8.5e-63	246.1	Bacilli	glnR	GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2001141		ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439			ko00000,ko00001,ko00002,ko02000,ko03000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25			Bacteria	1V6JE@1239,4HKM6@91061,COG0789@1,COG0789@2	NA|NA|NA	K	Transcriptional regulator
NHHNPPIF_01796	264199.stu1776	9.9e-263	912.1	Bacilli	glnA		6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727		R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147				Bacteria	1TNZA@1239,4HACE@91061,COG0174@1,COG0174@2	NA|NA|NA	E	glutamine synthetase
NHHNPPIF_01798	435842.HMPREF0848_01440	3.2e-41	174.5	Bacilli	pscB												Bacteria	1V8WM@1239,4HIMT@91061,COG3942@1,COG3942@2	NA|NA|NA	M	CHAP domain protein
NHHNPPIF_01799	264199.stu1774	0.0	1109.0	Bacilli	rnjA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360		ko:K12574	ko03018,map03018				ko00000,ko00001,ko01000,ko03019				Bacteria	1TQ9G@1239,4HAAP@91061,COG0595@1,COG0595@2	NA|NA|NA	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHHNPPIF_01800	264199.stu1773	2.5e-33	147.5	Bacilli	ykzG												Bacteria	1VEI7@1239,4HNSK@91061,COG5503@1,COG5503@2	NA|NA|NA	S	Belongs to the UPF0356 family
NHHNPPIF_01801	322159.STER_1747	2.1e-120	438.3	Bacilli	yeaZ	GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564	2.3.1.234	ko:K01409,ko:K14742			R10648	RC00070,RC00416	ko00000,ko01000,ko03016				Bacteria	1V4YX@1239,4HHD7@91061,COG1214@1,COG1214@2	NA|NA|NA	O	COG1214, inactive homolog of metal-dependent proteases
NHHNPPIF_01802	264199.stu1771	1.3e-73	282.3	Bacilli	rimI		2.3.1.128	ko:K03789					ko00000,ko01000,ko03009				Bacteria	1V6KU@1239,4HP50@91061,COG0454@1,COG0456@2	NA|NA|NA	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NHHNPPIF_01803	264199.stu1770	1.9e-186	658.3	Bacilli	tsaD	GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564	2.3.1.234	ko:K01409,ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	R10648	RC00070,RC00416	ko00000,ko00001,ko00002,ko01000,ko02044,ko03016	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4			Bacteria	1TQDR@1239,4HANB@91061,COG0533@1,COG0533@2	NA|NA|NA	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NHHNPPIF_01804	264199.stu1769	8.5e-117	426.4	Bacilli	azlC												Bacteria	1V64T@1239,4HH44@91061,COG1296@1,COG1296@2	NA|NA|NA	E	AzlC protein
NHHNPPIF_01805	264199.stu1768	8.8e-48	196.1	Bacteria	azlD												Bacteria	COG4392@1,COG4392@2	NA|NA|NA	E	branched-chain amino acid
NHHNPPIF_01806	264199.stu1767	0.0	1620.1	Bacilli	recD2		3.1.11.5	ko:K03581	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1TPZH@1239,4HATQ@91061,COG0507@1,COG0507@2	NA|NA|NA	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NHHNPPIF_01807	264199.stu1766	1.9e-112	411.8	Bacilli	lepB		3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060				ko00000,ko00001,ko01000,ko01002				Bacteria	1V7H9@1239,4HJSP@91061,COG0681@1,COG0681@2	NA|NA|NA	U	Belongs to the peptidase S26 family
NHHNPPIF_01808	322159.STER_1740	4.7e-160	570.5	Bacilli	rnhC	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470,ko:K03471	ko03030,map03030				ko00000,ko00001,ko01000,ko03032				Bacteria	1TQBE@1239,4H9QR@91061,COG1039@1,COG1039@2	NA|NA|NA	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHHNPPIF_01810	862969.SCI_0175	2.4e-103	382.1	Streptococcus anginosus group	repA												Bacteria	1VHQA@1239,2DP1C@1,3304N@2,42DYE@671232,4HPY6@91061	NA|NA|NA	S	Replication initiator protein A (RepA) N-terminus
NHHNPPIF_01811	1035184.HMPREF1042_2353	2.2e-46	191.4	Streptococcus anginosus group													Bacteria	1TW11@1239,2DIUA@1,3044T@2,42EI4@671232,4I4PX@91061	NA|NA|NA		
NHHNPPIF_01812	1035184.HMPREF1042_2352	1.4e-34	152.1	Bacteria													Bacteria	COG4443@1,COG4443@2	NA|NA|NA	S	Transcriptional Coactivator p15 (PC4)
NHHNPPIF_01814	1035184.HMPREF1042_2350	9.6e-103	379.8	Streptococcus anginosus group													Bacteria	1VY42@1239,2EFFF@1,33986@2,42EEK@671232,4HMPN@91061	NA|NA|NA		
NHHNPPIF_01816	888049.HMPREF8578_0773	1.5e-13	82.4	Streptococcus oralis													Bacteria	1TX2K@1239,1WQ63@1303,2DJ50@1,304RM@2,4I5YJ@91061	NA|NA|NA	S	PrgI family protein
NHHNPPIF_01817	1035184.HMPREF1042_2347	0.0	1384.4	Bacilli													Bacteria	1TPDR@1239,4HC47@91061,COG3451@1,COG3451@2	NA|NA|NA	U	Psort location Cytoplasmic, score
NHHNPPIF_01818	873447.SPB_0377	0.0	1199.1	Bacilli													Bacteria	1VPFZ@1239,4HFGV@91061,COG3942@1,COG3942@2	NA|NA|NA	M	CHAP domain protein
NHHNPPIF_01819	862969.SCI_0185	3.7e-64	251.5	Bacilli													Bacteria	1VDM9@1239,2DNFF@1,32X8K@2,4HNCS@91061	NA|NA|NA		
NHHNPPIF_01821	1035184.HMPREF1042_2341	1.4e-66	260.0	Streptococcus anginosus group													Bacteria	1TW0G@1239,2DIU0@1,3044E@2,42EHD@671232,4I4P6@91061	NA|NA|NA		
NHHNPPIF_01822	904306.HMPREF9192_0265	1.5e-12	77.8	Bacteria													Bacteria	COG3464@1,COG3464@2	NA|NA|NA		
NHHNPPIF_01823	264199.stu0824	3e-63	247.7	Bacilli	tdcF		3.5.99.10	ko:K09022			R11098,R11099	RC03275,RC03354	ko00000,ko01000				Bacteria	1V6HG@1239,4HKEF@91061,COG0251@1,COG0251@2	NA|NA|NA	J	endoribonuclease L-PSP
NHHNPPIF_01824	322159.STER_0869	4.4e-123	447.2	Bacilli	queC		6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100		R09978	RC00959	ko00000,ko00001,ko01000,ko03016				Bacteria	1TP4Z@1239,4HB1Y@91061,COG0603@1,COG0603@2	NA|NA|NA	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NHHNPPIF_01825	264199.stu0826	2.2e-81	308.1	Bacilli	queD		4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016				Bacteria	1V9HU@1239,4HJEX@91061,COG0720@1,COG0720@2	NA|NA|NA	H	synthase
NHHNPPIF_01826	264199.stu0827	3.9e-133	480.7	Bacilli	queE	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047	1.97.1.4,4.3.99.3	ko:K04068,ko:K10026	ko00790,ko01100,map00790,map01100		R04710,R10002	RC02989	ko00000,ko00001,ko01000,ko03016				Bacteria	1TQ58@1239,4HAJ3@91061,COG0602@1,COG0602@2	NA|NA|NA	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NHHNPPIF_01827	264199.stu0828	2.5e-94	351.3	Bacilli	queF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016651,GO:0016657,GO:0018130,GO:0019438,GO:0033739,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.7.1.13	ko:K06879,ko:K09457	ko00790,ko01100,map00790,map01100		R07605	RC01875	ko00000,ko00001,ko01000,ko03016			iSFV_1184.SFV_2663,iSF_1195.SF2807,iS_1188.S3002	Bacteria	1TPYC@1239,4HB14@91061,COG0780@1,COG0780@2	NA|NA|NA	S	Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
NHHNPPIF_01828	264199.stu0442	2.1e-114	419.5	Bacteria	usp		3.5.1.104,3.5.1.28	ko:K15125,ko:K17733,ko:K21449,ko:K21471,ko:K22278,ko:K22409	ko05133,map05133				ko00000,ko00001,ko00536,ko01000,ko01002,ko01011,ko02000	1.B.40.2	CBM50		Bacteria	COG1388@1,COG1388@2,COG3942@1,COG3942@2	NA|NA|NA	S	pathogenesis
NHHNPPIF_01829	264199.stu0441	7.4e-35	152.5	Bacilli	yozE												Bacteria	1VFI4@1239,4HR7P@91061,COG4479@1,COG4479@2	NA|NA|NA	S	Belongs to the UPF0346 family
NHHNPPIF_01830	322159.STER_0476	7e-161	573.2	Bacilli	cvfB			ko:K00243					ko00000				Bacteria	1TQ1Z@1239,4HDAZ@91061,COG2996@1,COG2996@2	NA|NA|NA	S	Protein conserved in bacteria
NHHNPPIF_01831	322159.STER_0475	1.3e-91	342.4	Bacilli	frr	GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576		ko:K02838					ko00000,ko03012				Bacteria	1V1F2@1239,4HFSH@91061,COG0233@1,COG0233@2	NA|NA|NA	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NHHNPPIF_01832	322159.STER_0474	4.9e-131	473.8	Bacilli	pyrH	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100		R00158	RC00002	ko00000,ko00001,ko01000			iSB619.SA_RS06240	Bacteria	1TPXN@1239,4H9UB@91061,COG0528@1,COG0528@2	NA|NA|NA	F	Catalyzes the reversible phosphorylation of UMP to UDP
NHHNPPIF_01833	264199.stu0437	4.5e-77	293.9	Bacilli	sptS		2.7.13.3	ko:K11328	ko02020,map02020	M00464			ko00000,ko00001,ko00002,ko01000,ko01001,ko02022				Bacteria	1UHQH@1239,4HAHG@91061,COG0642@1,COG0642@2	NA|NA|NA	T	Histidine kinase
NHHNPPIF_01834	1046629.Ssal_01762	1.4e-45	188.7	Bacilli													Bacteria	1VF01@1239,4HPKN@91061,COG0454@1,COG0456@2	NA|NA|NA	K	Acetyltransferase (GNAT) family
NHHNPPIF_01835	264199.stu0434	0.0	1121.7	Bacilli	lmrA2			ko:K06147					ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21			Bacteria	1TP0B@1239,4HA3S@91061,COG1132@1,COG1132@2	NA|NA|NA	V	abc transporter atp-binding protein
NHHNPPIF_01836	264199.stu0433	0.0	1077.4	Bacilli	lmrA1			ko:K02021,ko:K06147,ko:K06148,ko:K18887	ko02010,map02010	M00706			ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21			Bacteria	1TP0B@1239,4H9SC@91061,COG1132@1,COG1132@2	NA|NA|NA	V	abc transporter atp-binding protein
NHHNPPIF_01837	264199.stu0432	7.2e-77	293.1	Bacteria													Bacteria	COG1846@1,COG1846@2	NA|NA|NA	K	DNA-binding transcription factor activity
NHHNPPIF_01838	322159.STER_0468	8.7e-69	266.2	Bacilli	def_1		3.5.1.31,3.5.1.88	ko:K01450,ko:K01462	ko00270,ko00630,map00270,map00630		R00653	RC00165,RC00323	ko00000,ko00001,ko01000				Bacteria	1V73T@1239,4HGYC@91061,COG0242@1,COG0242@2	NA|NA|NA	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins
NHHNPPIF_01839	264199.stu0430	6.9e-256	889.4	Bacilli	gdhA		1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100		R00248	RC00006,RC02799	ko00000,ko00001,ko01000				Bacteria	1TP45@1239,4HAEI@91061,COG0334@1,COG0334@2	NA|NA|NA	E	Belongs to the Glu Leu Phe Val dehydrogenases family
NHHNPPIF_01840	264199.stu0429	1.2e-163	582.4	Bacilli	nadD		2.7.1.22,2.7.7.1,2.7.7.18,3.6.1.55	ko:K00969,ko:K03574,ko:K06211	ko00760,ko01100,map00760,map01100	M00115	R00137,R02324,R03005	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko03000,ko03400			iIT341.HP1337	Bacteria	1TQ29@1239,4HBZT@91061,COG1057@1,COG1057@2,COG3172@1,COG3172@2	NA|NA|NA	H	adenylyltransferase
NHHNPPIF_01841	322159.STER_0465	1e-139	502.7	Bacilli			3.6.1.13,3.6.1.55	ko:K01515,ko:K03574	ko00230,map00230		R01054	RC00002	ko00000,ko00001,ko01000,ko03400				Bacteria	1TST7@1239,4HEFP@91061,COG1051@1,COG1051@2	NA|NA|NA	F	AdP-ribose pyrophosphatase
NHHNPPIF_01842	1123298.KB904062_gene886	3.3e-25	121.7	Bacteria													Bacteria	COG3247@1,COG3247@2	NA|NA|NA	U	response to pH
NHHNPPIF_01843	322159.STER_0462	0.0	1198.0	Bacilli	yfmR			ko:K15738					ko00000,ko02000	3.A.1.120.6			Bacteria	1TPAX@1239,4H9TK@91061,COG0488@1,COG0488@2	NA|NA|NA	S	abc transporter atp-binding protein
NHHNPPIF_01844	264199.stu0425	7.4e-225	786.2	Bacilli	cca		2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018		R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019				Bacteria	1TQ2A@1239,4HB2W@91061,COG0617@1,COG0617@2	NA|NA|NA	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NHHNPPIF_01845	264199.stu0424	5.1e-139	500.4	Bacilli	dapB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0070402,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000			iJN678.dapB,iNJ661.Rv2773c,iYO844.BSU22490	Bacteria	1TR9D@1239,4HA5X@91061,COG0289@1,COG0289@2	NA|NA|NA	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NHHNPPIF_01846	904306.HMPREF9192_0332	5.5e-75	287.0	Bacilli	XK27_08360												Bacteria	1TRM7@1239,4HVKJ@91061,COG1307@1,COG1307@2	NA|NA|NA	S	EDD domain protein, DegV family
NHHNPPIF_01847	904306.HMPREF9192_0332	6.4e-61	240.0	Bacilli	XK27_08360												Bacteria	1TRM7@1239,4HVKJ@91061,COG1307@1,COG1307@2	NA|NA|NA	S	EDD domain protein, DegV family
NHHNPPIF_01848	322159.STER_0458	2.6e-64	251.1	Bacilli	WQ51_03320												Bacteria	1VHA6@1239,4HPTC@91061,COG4835@1,COG4835@2	NA|NA|NA	S	cog cog4835
NHHNPPIF_01849	322159.STER_0457	6.7e-122	443.4	Bacteria	ydaF_2												Bacteria	COG1670@1,COG1670@2	NA|NA|NA	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NHHNPPIF_01850	1046629.Ssal_01778	1.5e-46	191.8	Bacilli	rpmA	GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904		ko:K02899	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V6HW@1239,4HIMN@91061,COG0211@1,COG0211@2	NA|NA|NA	J	Belongs to the bacterial ribosomal protein bL27 family
NHHNPPIF_01851	264199.stu0417	4.5e-49	200.3	Bacilli	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02888	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V9YH@1239,4HIGK@91061,COG0261@1,COG0261@2	NA|NA|NA	J	This protein binds to 23S rRNA in the presence of protein L20
NHHNPPIF_01852	1046629.Ssal_01780	6.4e-29	132.9	Bacteria			2.3.1.128	ko:K03789					ko00000,ko01000,ko03009				Bacteria	COG0454@1,COG0456@2	NA|NA|NA	K	acetyltransferase
NHHNPPIF_01853	1046629.Ssal_01780	4.9e-39	167.2	Bacteria			2.3.1.128	ko:K03789					ko00000,ko01000,ko03009				Bacteria	COG0454@1,COG0456@2	NA|NA|NA	K	acetyltransferase
NHHNPPIF_01854	264199.stu0414	3e-256	890.6	Firmicutes	gtf2												Bacteria	1TQZR@1239,COG0438@1,COG0438@2	NA|NA|NA	M	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NHHNPPIF_01855	322159.STER_0452	4.9e-295	1019.6	Bacilli	gtf1		2.4.1.52	ko:K00712					ko00000,ko01000,ko01003		GT4		Bacteria	1TR6K@1239,4HGDG@91061,COG0438@1,COG0438@2	NA|NA|NA	M	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NHHNPPIF_01856	264199.stu0412	1.2e-225	788.9	Bacilli	thiI	GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122		R07461		ko00000,ko00001,ko01000,ko03016			iECNA114_1301.ECNA114_0400,iECO26_1355.ECO26_0455,iECSF_1327.ECSF_0383,iSDY_1059.SDY_0307	Bacteria	1TPNW@1239,4HAV9@91061,COG0301@1,COG0301@2	NA|NA|NA	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NHHNPPIF_01857	264199.stu0411	1.2e-208	732.3	Bacilli	iscS2		2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122		R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029				Bacteria	1TP21@1239,4HAEE@91061,COG1104@1,COG1104@2	NA|NA|NA	E	Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
NHHNPPIF_01859	264199.stu0409	1.5e-241	841.6	Bacilli	folC		6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000			iLJ478.TM0166	Bacteria	1TPX5@1239,4HBJM@91061,COG0285@1,COG0285@2	NA|NA|NA	H	Belongs to the folylpolyglutamate synthase family
NHHNPPIF_01860	264199.stu0408	3e-259	900.6	Bacilli	gor	GO:0000166,GO:0003674,GO:0003824,GO:0004362,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0015037,GO:0015038,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071949,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918		R00094,R00115	RC00011	ko00000,ko00001,ko01000			iZ_1308.Z4900	Bacteria	1TQFH@1239,4HCT8@91061,COG1249@1,COG1249@2	NA|NA|NA	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NHHNPPIF_01861	1046629.Ssal_01791	0.0	1173.7	Bacilli	fruA		2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1			Bacteria	1TPKU@1239,4H9KR@91061,COG1299@1,COG1299@2,COG1445@1,COG1445@2,COG1762@1,COG1762@2	NA|NA|NA	G	phosphotransferase system
NHHNPPIF_01862	264199.stu0400	3.8e-165	587.4	Bacilli	pfkB		2.7.1.11,2.7.1.56	ko:K00882,ko:K16370	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00345	R00756,R02071,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQ36@1239,4HANU@91061,COG1105@1,COG1105@2	NA|NA|NA	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NHHNPPIF_01863	904306.HMPREF9192_0316	1.2e-121	442.6	Bacilli	fruR			ko:K03436					ko00000,ko03000				Bacteria	1TSF8@1239,4HDT9@91061,COG1349@1,COG1349@2	NA|NA|NA	K	transcriptional
NHHNPPIF_01864	264199.stu0398	1.8e-84	318.5	Firmicutes				ko:K07485					ko00000				Bacteria	1TQ93@1239,COG3464@1,COG3464@2	NA|NA|NA	L	Transposase
NHHNPPIF_01865	264199.stu0397	1.3e-205	722.6	Bacilli	rny	GO:0003674,GO:0005488,GO:0005515,GO:0042802		ko:K05802,ko:K18682	ko03018,map03018				ko00000,ko00001,ko01000,ko02000,ko03019	1.A.23.1.1			Bacteria	1TP48@1239,4HC9J@91061,COG1418@1,COG1418@2,COG4372@1,COG4372@2	NA|NA|NA	D	Endoribonuclease that initiates mRNA decay
NHHNPPIF_01866	1046629.Ssal_01795	4.7e-90	337.0	Bacilli	luxS	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009116,GO:0009119,GO:0009372,GO:0009987,GO:0010699,GO:0016053,GO:0016829,GO:0016846,GO:0017144,GO:0019284,GO:0019752,GO:0023052,GO:0033353,GO:0034641,GO:0042278,GO:0043094,GO:0043102,GO:0043436,GO:0043768,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046128,GO:0046394,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0051704,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000			iECIAI39_1322.ECIAI39_2877,iPC815.YPO3300	Bacteria	1V1V3@1239,4HFR0@91061,COG1854@1,COG1854@2	NA|NA|NA	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NHHNPPIF_01867	322159.STER_0439	1.5e-138	498.8	Bacilli	accA		2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000				Bacteria	1UHNS@1239,4HA4C@91061,COG0825@1,COG0825@2	NA|NA|NA	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NHHNPPIF_01868	322159.STER_0438	1.1e-158	565.8	Bacilli	accD		2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP4U@1239,4HAI7@91061,COG0777@1,COG0777@2	NA|NA|NA	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NHHNPPIF_01869	322159.STER_0437	1.4e-256	891.7	Bacilli	accC	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000			iSF_1195.SF3294	Bacteria	1TP16@1239,4HARK@91061,COG0439@1,COG0439@2	NA|NA|NA	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NHHNPPIF_01870	1046629.Ssal_01800	4.3e-71	273.9	Bacilli	fabZ		3.5.1.108,4.2.1.59	ko:K02372,ko:K16363	ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212	M00060,M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005				Bacteria	1V6EX@1239,4HGX1@91061,COG0764@1,COG0764@2	NA|NA|NA	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NHHNPPIF_01871	322159.STER_0435	7e-57	226.9	Bacilli	accB		2.3.1.12,4.1.1.3	ko:K00627,ko:K01571,ko:K02160	ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00307,M00376	R00209,R00217,R00742,R02569	RC00004,RC00040,RC00367,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1			Bacteria	1VAB7@1239,4HKCS@91061,COG0511@1,COG0511@2	NA|NA|NA	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NHHNPPIF_01872	322159.STER_0434	1.5e-233	815.1	Bacilli	fabF		2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	1TPA7@1239,4H9SD@91061,COG0304@1,COG0304@2	NA|NA|NA	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NHHNPPIF_01873	322159.STER_0433	1.6e-126	458.8	Bacilli													Bacteria	1TP76@1239,4HAA6@91061,COG1028@1,COG1028@2	NA|NA|NA	IQ	reductase
NHHNPPIF_01874	264199.stu0386	1.9e-164	585.1	Bacilli	fabD		2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	1TPB7@1239,4HBCU@91061,COG0331@1,COG0331@2	NA|NA|NA	I	Malonyl CoA-acyl carrier protein transacylase
NHHNPPIF_01875	322159.STER_0431	6.8e-173	613.2	Bacilli	fabK		1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004			iHN637.CLJU_RS20775	Bacteria	1TPC3@1239,4H9T0@91061,COG2070@1,COG2070@2	NA|NA|NA	S	2-Nitropropane dioxygenase
NHHNPPIF_01876	435842.HMPREF0848_00012	2.6e-30	137.5	Bacilli	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509		ko:K02078					ko00000,ko00001				Bacteria	1VGIY@1239,4HP0V@91061,COG0236@1,COG0236@2	NA|NA|NA	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHHNPPIF_01877	322159.STER_0429	2.3e-173	614.8	Bacilli	fabH		2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004				Bacteria	1TP0K@1239,4HATK@91061,COG0332@1,COG0332@2	NA|NA|NA	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NHHNPPIF_01878	904306.HMPREF9192_0286	2.3e-72	278.1	Bacilli	marR												Bacteria	1V6GY@1239,4HIMR@91061,COG1846@1,COG1846@2	NA|NA|NA	K	Transcriptional regulator, MarR family
NHHNPPIF_01879	264199.stu0380	1e-137	496.1	Bacilli	phaB	GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006635,GO:0006636,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009987,GO:0016042,GO:0016053,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0033559,GO:0034017,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:0072330,GO:1901575,GO:1901576	5.3.3.14,5.3.3.18	ko:K15866,ko:K18474	ko00061,ko00360,ko01120,map00061,map00360,map01120		R07639,R09837,R09839	RC00004,RC00326,RC01078,RC02689,RC03003	ko00000,ko00001,ko01000,ko01004				Bacteria	1TQ2V@1239,4HBT0@91061,COG1024@1,COG1024@2	NA|NA|NA	I	Belongs to the enoyl-CoA hydratase isomerase family
NHHNPPIF_01880	322159.STER_0426	1.6e-114	418.7	Bacilli													Bacteria	1V7XM@1239,4IPJK@91061,COG0637@1,COG0637@2	NA|NA|NA	S	Haloacid dehalogenase-like hydrolase
NHHNPPIF_01881	322159.STER_0425	5.9e-255	886.3	Bacilli	lysC	GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000			iYO844.BSU03790	Bacteria	1TPQJ@1239,4HAEP@91061,COG0527@1,COG0527@2	NA|NA|NA	E	Belongs to the aspartokinase family
NHHNPPIF_01882	322159.STER_0424	6.7e-192	676.4	Bacilli	asnA	GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230		R00483	RC00010	ko00000,ko00001,ko01000			iAPECO1_1312.APECO1_2719,iECOK1_1307.ECOK1_4193,iECS88_1305.ECS88_4166,iUMN146_1321.UM146_18910,iUTI89_1310.UTI89_C4299	Bacteria	1TP28@1239,4HAEC@91061,COG2502@1,COG2502@2	NA|NA|NA	E	aspartate--ammonia ligase
NHHNPPIF_01883	264199.stu0376	1.4e-259	901.7	Bacilli	rumA		2.1.1.190,2.1.1.35	ko:K00557,ko:K03215					ko00000,ko01000,ko03009,ko03016				Bacteria	1TP4H@1239,4HA6M@91061,COG2265@1,COG2265@2	NA|NA|NA	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHHNPPIF_01884	264199.stu0375	7.3e-133	479.9	Bacilli	recX	GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019899,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496	2.4.1.337	ko:K03565,ko:K19002	ko00561,ko01100,map00561,map01100		R10850	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003,ko03400		GT4		Bacteria	1V72V@1239,4HKE3@91061,COG2137@1,COG2137@2	NA|NA|NA	S	Regulatory protein RecX
NHHNPPIF_01885	264199.stu0374	7.8e-102	376.3	Bacilli	ygaC			ko:K07586					ko00000				Bacteria	1TRX8@1239,4H9NM@91061,COG3557@1,COG3557@2	NA|NA|NA	J	Belongs to the UPF0374 family
NHHNPPIF_01886	264199.stu0373	4.1e-107	394.0	Bacilli													Bacteria	1W4V4@1239,2F8BM@1,340QP@2,4HR72@91061	NA|NA|NA	S	Domain of unknown function (DUF1803)
NHHNPPIF_01887	322159.STER_0042	2e-96	359.8	Bacilli	usp		3.5.1.28	ko:K21471,ko:K22409					ko00000,ko01000,ko01002,ko01011		CBM50		Bacteria	1VCXB@1239,4IS6H@91061,COG3883@1,COG3883@2,COG3942@1,COG3942@2	NA|NA|NA	S	CHAP domain
NHHNPPIF_01888	322159.STER_0041	8.2e-88	329.7	Bacteria	mreD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944		ko:K03571					ko00000,ko03036	9.B.157.1			Bacteria	COG2891@1,COG2891@2	NA|NA|NA	M	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NHHNPPIF_01889	322159.STER_0040	3.6e-138	497.7	Bacilli	mreC	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963		ko:K03570					ko00000,ko03036	9.B.157.1			Bacteria	1TR1V@1239,4HB0K@91061,COG1792@1,COG1792@2	NA|NA|NA	M	Involved in formation and maintenance of cell shape
NHHNPPIF_01893	322159.STER_0767	4.2e-92	344.0	Bacilli	dps			ko:K04047					ko00000,ko03036				Bacteria	1VCVJ@1239,4HMBD@91061,COG0783@1,COG0783@2	NA|NA|NA	P	Belongs to the Dps family
NHHNPPIF_01894	322159.STER_0768	4.4e-79	300.4	Bacilli	perR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141		ko:K03711,ko:K09825					ko00000,ko03000				Bacteria	1V400@1239,4HHF8@91061,COG0735@1,COG0735@2	NA|NA|NA	P	Belongs to the Fur family
NHHNPPIF_01895	264199.stu0727	1.9e-27	127.9	Bacilli	yqgQ												Bacteria	1VK83@1239,4HRG2@91061,COG4483@1,COG4483@2	NA|NA|NA	S	protein conserved in bacteria
NHHNPPIF_01896	264199.stu0728	7.8e-177	626.3	Bacilli	glk	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000			iSB619.SA_RS07790	Bacteria	1TPKW@1239,4HBAU@91061,COG1940@1,COG1940@2	NA|NA|NA	G	Glucokinase
NHHNPPIF_01897	264199.stu0729	0.0	1194.1	Bacilli	typA	GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840		ko:K06207					ko00000				Bacteria	1TQ5Y@1239,4HAQ6@91061,COG1217@1,COG1217@2	NA|NA|NA	T	GTP-binding protein TypA
NHHNPPIF_01899	264199.stu0731	1.6e-252	878.2	Bacilli	murD		6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100		R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011				Bacteria	1TQ3P@1239,4HA5P@91061,COG0771@1,COG0771@2	NA|NA|NA	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NHHNPPIF_01900	264199.stu0732	3.9e-201	707.2	Bacilli	murG		2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112		R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011		GT28		Bacteria	1TQFT@1239,4HBAQ@91061,COG0707@1,COG0707@2	NA|NA|NA	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NHHNPPIF_01901	264199.stu0733	8.2e-170	603.2	Firmicutes	divIB			ko:K03589	ko04112,map04112				ko00000,ko00001,ko03036				Bacteria	1VHEY@1239,COG1589@1,COG1589@2	NA|NA|NA	D	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NHHNPPIF_01902	264199.stu0734	2.3e-251	874.4	Bacilli	ftsA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562		ko:K03590	ko04112,map04112				ko00000,ko00001,ko03036,ko04812				Bacteria	1TP1Z@1239,4H9NF@91061,COG0849@1,COG0849@2	NA|NA|NA	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NHHNPPIF_01903	264199.stu0735	2.7e-236	824.3	Bacilli	ftsZ	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363		ko:K03531	ko04112,map04112				ko00000,ko00001,ko02048,ko03036,ko04812				Bacteria	1TP6W@1239,4H9WZ@91061,COG0206@1,COG0206@2	NA|NA|NA	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NHHNPPIF_01904	264199.stu0736	5.1e-122	443.7	Bacilli	ylmE	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363		ko:K06997					ko00000				Bacteria	1TRDN@1239,4HC45@91061,COG0325@1,COG0325@2	NA|NA|NA	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NHHNPPIF_01905	322159.STER_0779	1.4e-96	359.0	Bacteria	sepF	GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0044464,GO:0051301,GO:0071840,GO:0071944,GO:0090529		ko:K09772					ko00000,ko03036				Bacteria	COG1799@1,COG1799@2	NA|NA|NA	D	cell septum assembly
NHHNPPIF_01906	322159.STER_0780	2e-34	151.4	Bacteria	yggT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K02221					ko00000,ko02044				Bacteria	COG0762@1,COG0762@2	NA|NA|NA	D	integral membrane protein
NHHNPPIF_01907	264199.stu0739	8e-143	513.1	Bacteria	ylmH			ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507			ko00000,ko00001,ko00002,ko01001,ko02022,ko02035				Bacteria	COG2302@1,COG2302@2	NA|NA|NA	T	S4 RNA-binding domain
NHHNPPIF_01908	322159.STER_0782	3.3e-134	484.6	Bacilli	divIVA			ko:K04074					ko00000,ko03036				Bacteria	1V27M@1239,4HJYN@91061,COG3599@1,COG3599@2	NA|NA|NA	D	Cell division protein DivIVA
NHHNPPIF_01909	264199.stu0741	0.0	1869.7	Bacilli	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iG2583_1286.G2583_0027,iPC815.YPO0475	Bacteria	1TPS7@1239,4HAWB@91061,COG0060@1,COG0060@2	NA|NA|NA	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NHHNPPIF_01910	322159.STER_0786	7.9e-230	802.7	Bacilli	mntH												Bacteria	1V04N@1239,4HBF6@91061,COG1914@1,COG1914@2	NA|NA|NA	P	Mn2 and Fe2 transporters of the NRAMP family
NHHNPPIF_01911	264199.stu0746	2e-45	188.0	Bacilli	rpmE2	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034224,GO:0034641,GO:0034645,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0120127,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02909	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1VEGU@1239,4HNQF@91061,COG0254@1,COG0254@2	NA|NA|NA	J	50S ribosomal protein L31
NHHNPPIF_01912	264199.stu0747	1e-173	615.9	Bacilli	apbE		2.7.1.180	ko:K03734					ko00000,ko01000				Bacteria	1TR9C@1239,4HDFE@91061,COG1477@1,COG1477@2	NA|NA|NA	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NHHNPPIF_01913	264199.stu0748	6.5e-176	623.2	Bacilli	nrnA	GO:0008150,GO:0040007	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120		R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400				Bacteria	1TPXX@1239,4H9ZW@91061,COG0618@1,COG0618@2	NA|NA|NA	S	domain protein
NHHNPPIF_01914	322159.STER_0790	2.6e-154	551.2	Bacilli	gst			ko:K11209					ko00000,ko01000				Bacteria	1TPZ7@1239,4HD0K@91061,COG0625@1,COG0625@2	NA|NA|NA	O	Glutathione S-transferase
NHHNPPIF_01915	264199.stu0750	6.7e-187	659.8	Bacilli	add		3.5.4.4	ko:K01488,ko:K02029	ko00230,ko01100,ko05340,map00230,map01100,map05340	M00236	R01560,R02556	RC00477	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3		iHN637.CLJU_RS13960	Bacteria	1U44B@1239,4HCES@91061,COG1816@1,COG1816@2	NA|NA|NA	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NHHNPPIF_01916	264199.stu0751	3.5e-111	407.5	Bacilli	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100		R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000			iAF1260.b1238,iBWG_1329.BWG_1065,iECDH10B_1368.ECDH10B_1298,iECDH1ME8569_1439.ECDH1ME8569_1176,iEcDH1_1363.EcDH1_2411,iJO1366.b1238,iJR904.b1238,iPC815.YPO2176,iY75_1357.Y75_RS06470	Bacteria	1TRVM@1239,4HA4A@91061,COG1435@1,COG1435@2	NA|NA|NA	F	thymidine kinase
NHHNPPIF_01917	264199.stu0752	1.8e-190	671.8	Bacilli	prfA			ko:K02835					ko00000,ko03012				Bacteria	1TQ7V@1239,4H9MB@91061,COG0216@1,COG0216@2	NA|NA|NA	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NHHNPPIF_01918	322159.STER_0794	6.8e-153	546.6	Bacilli	prmB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009007,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0032775,GO:0034641,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044728,GO:0046483,GO:0071704,GO:0090304,GO:0140096,GO:0140097,GO:1901360,GO:1901564	2.1.1.297,2.1.1.298	ko:K02493,ko:K07320			R10806	RC00003,RC03279	ko00000,ko01000,ko03009,ko03012				Bacteria	1TSMA@1239,4HC6W@91061,COG2890@1,COG2890@2	NA|NA|NA	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NHHNPPIF_01919	264199.stu0754	2.5e-109	401.4	Bacilli	ywlC	GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	2.7.7.87,3.1.3.48	ko:K01104,ko:K07566			R10463	RC00745	ko00000,ko01000,ko03009,ko03016				Bacteria	1TP1I@1239,4HA7W@91061,COG0009@1,COG0009@2	NA|NA|NA	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NHHNPPIF_01920	322159.STER_0796	2e-233	814.7	Bacilli	glyA		2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQVM@1239,4HA5K@91061,COG0112@1,COG0112@2	NA|NA|NA	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NHHNPPIF_01921	264199.stu0756	1e-176	625.9	Bacilli	ndpA	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003727,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0009295,GO:0042802,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0097159,GO:1901363		ko:K06899					ko00000,ko03036				Bacteria	1V437@1239,4IQXJ@91061,COG3081@1,COG3081@2	NA|NA|NA	S	37-kD nucleoid-associated bacterial protein
NHHNPPIF_01922	264199.stu0757	1.6e-106	392.1	Bacteria	pvaA			ko:K02395					ko00000,ko02035				Bacteria	COG0741@1,COG0741@2	NA|NA|NA	M	lytic transglycosylase activity
NHHNPPIF_01923	322159.STER_0799	0.0	1082.0	Bacilli	yfiB1			ko:K06147,ko:K06148,ko:K18887	ko02010,map02010	M00706			ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21			Bacteria	1TP0B@1239,4H9SC@91061,COG1132@1,COG1132@2	NA|NA|NA	V	abc transporter atp-binding protein
NHHNPPIF_01924	322159.STER_0800	0.0	1098.2	Bacilli	XK27_10035			ko:K06147,ko:K11085	ko02010,map02010				ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21			Bacteria	1TP0B@1239,4HCVN@91061,COG1132@1,COG1132@2	NA|NA|NA	V	abc transporter atp-binding protein
NHHNPPIF_01925	1000570.HMPREF9966_1459	1.2e-09	68.6	Streptococcus anginosus group													Bacteria	1TW0K@1239,2DIU2@1,3044G@2,42EHI@671232,4I4PC@91061	NA|NA|NA	S	D-Ala-teichoic acid biosynthesis protein
NHHNPPIF_01926	264199.stu0761	6e-296	1022.7	Bacilli	dltA	GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016208,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0022857,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.13	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	M00725	R02718	RC00037,RC00094	ko00000,ko00001,ko00002,ko01000,ko01504				Bacteria	1TPTH@1239,4HAHU@91061,COG1020@1,COG1020@2	NA|NA|NA	Q	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHHNPPIF_01927	264199.stu0762	1.6e-235	821.6	Bacilli	dltB			ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725			ko00000,ko00001,ko00002,ko01504				Bacteria	1TP52@1239,4HBQG@91061,COG1696@1,COG1696@2	NA|NA|NA	M	Membrane protein involved in D-alanine export
NHHNPPIF_01928	264199.stu0763	2.2e-35	154.5	Bacilli	dltC	GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.1.1.13	ko:K02078,ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	M00725	R02718	RC00037,RC00094	ko00000,ko00001,ko00002,ko01000,ko01504				Bacteria	1VFQI@1239,4HNIH@91061,COG0236@1,COG0236@2	NA|NA|NA	IQ	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHHNPPIF_01929	322159.STER_0805	3.7e-227	793.9	Bacilli	dltD			ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725			ko00000,ko00001,ko00002,ko01504				Bacteria	1TSZU@1239,4HC3H@91061,COG3966@1,COG3966@2	NA|NA|NA	M	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NHHNPPIF_01930	264199.stu1787	1.4e-86	325.5	Firmicutes				ko:K07497					ko00000				Bacteria	1TQQY@1239,COG2801@1,COG2801@2	NA|NA|NA	L	Integrase core domain protein
NHHNPPIF_01931	1069533.Sinf_0805	7.1e-28	129.4	Bacteria				ko:K07483					ko00000				Bacteria	COG2963@1,COG2963@2	NA|NA|NA	L	transposase activity
NHHNPPIF_01933	997830.HMPREF1124_0825	6.4e-50	203.8	Streptococcus infantis													Bacteria	1TWKB@1239,2BKU4@1,32FAD@2,43GHI@68892,4I5E1@91061	NA|NA|NA		
NHHNPPIF_01935	1123312.KB904580_gene880	2.1e-120	438.3	Bacilli				ko:K07043					ko00000				Bacteria	1VCK6@1239,4HGVM@91061,COG1451@1,COG1451@2	NA|NA|NA	S	Protein of unknown function (DUF2786)
NHHNPPIF_01937	1123315.AUIP01000012_gene1984	4.2e-278	963.4	Bacilli	repE												Bacteria	1UBUD@1239,4HB0A@91061,COG1959@1,COG1959@2	NA|NA|NA	K	Primase C terminal 1 (PriCT-1)
NHHNPPIF_01939	1035189.HMPREF9954_1862	6.1e-15	86.3	Streptococcus infantis													Bacteria	1TWN4@1239,2DJ09@1,304FH@2,43GM5@68892,4I5FY@91061	NA|NA|NA		
NHHNPPIF_01940	997830.HMPREF1124_0830	3.8e-40	171.0	Streptococcus infantis													Bacteria	1TWJQ@1239,2DIZ5@1,304E3@2,43GFN@68892,4I5D8@91061	NA|NA|NA		
NHHNPPIF_01941	1035189.HMPREF9954_1860	4.6e-34	151.0	Streptococcus infantis													Bacteria	1TWK7@1239,2DIZC@1,304ED@2,43GH6@68892,4I5DW@91061	NA|NA|NA	S	Thioredoxin
NHHNPPIF_01942	997830.HMPREF1124_0832	1.2e-14	85.5	Streptococcus infantis													Bacteria	1TWNW@1239,2DJ0H@1,304FT@2,43GN8@68892,4I5GQ@91061	NA|NA|NA		
NHHNPPIF_01945	1035189.HMPREF9954_1858	3.7e-89	335.1	Streptococcus infantis													Bacteria	1W27X@1239,2DCHT@1,2ZE7E@2,43GGG@68892,4I25E@91061	NA|NA|NA		
NHHNPPIF_01948	997830.HMPREF1124_0837	3.6e-20	104.4	Streptococcus infantis													Bacteria	1TWM0@1239,29P5X@1,30A42@2,43GJG@68892,4I5ET@91061	NA|NA|NA	S	the current gene model (or a revised gene model) may contain a frame shift
NHHNPPIF_01949	1035189.HMPREF9954_1854	1.7e-36	158.7	Streptococcus infantis													Bacteria	1TWKR@1239,2DIZJ@1,304EM@2,43GIX@68892,4I5EH@91061	NA|NA|NA	S	the current gene model (or a revised gene model) may contain a frame shift
NHHNPPIF_01950	1123315.AUIP01000012_gene1974	6.7e-142	510.0	Bacilli	ada		3.2.2.21	ko:K13529,ko:K15051	ko03410,map03410				ko00000,ko00001,ko01000,ko03000,ko03400				Bacteria	1TR37@1239,4HK7D@91061,COG2169@1,COG2169@2	NA|NA|NA	F	DNA/RNA non-specific endonuclease
NHHNPPIF_01951	997830.HMPREF1124_0841	1.6e-39	169.1	Streptococcus infantis													Bacteria	1TWM2@1239,2DIZQ@1,304EU@2,43GJQ@68892,4I5EW@91061	NA|NA|NA		
NHHNPPIF_01952	482234.SCAZ3_00255	0.0	1464.9	Bacilli	ruvB		3.6.4.12	ko:K03551,ko:K07126	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1V0DS@1239,4HENV@91061,COG2255@1,COG2255@2	NA|NA|NA	L	four-way junction helicase activity
NHHNPPIF_01953	1035189.HMPREF9954_1844	7.5e-18	96.3	Streptococcus infantis													Bacteria	1TWMS@1239,2DJ03@1,304F9@2,43GKP@68892,4I5FI@91061	NA|NA|NA		
NHHNPPIF_01954	482234.SCAZ3_00265	0.0	3336.2	Bacilli													Bacteria	1UICF@1239,4ISNE@91061,COG0358@1,COG0358@2,COG2856@1,COG2856@2	NA|NA|NA	EL	Toprim-like
NHHNPPIF_01956	482234.SCAZ3_00275	0.0	1133.6	Bacilli	topB		5.99.1.2	ko:K03169					ko00000,ko01000,ko03032				Bacteria	1TPJD@1239,4HBQF@91061,COG0550@1,COG0550@2	NA|NA|NA	L	Topoisomerase IA
NHHNPPIF_01957	482234.SCAZ3_00280	0.0	1158.7	Bacilli	clpB			ko:K03694,ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213				ko00000,ko00001,ko03110				Bacteria	1TPMU@1239,4HACY@91061,COG0542@1,COG0542@2	NA|NA|NA	O	Belongs to the ClpA ClpB family
NHHNPPIF_01958	1035189.HMPREF9954_1835	2.9e-33	147.9	Streptococcus infantis													Bacteria	1TWKN@1239,2DIZG@1,304EJ@2,43GIM@68892,4I5EE@91061	NA|NA|NA		
NHHNPPIF_01959	1123311.KB904459_gene592	3.4e-197	694.1	Bacilli													Bacteria	1W5ZH@1239,2DCJK@1,2ZEEP@2,4I1YG@91061	NA|NA|NA		
NHHNPPIF_01960	862969.SCI_0808	1.8e-30	139.8	Streptococcus anginosus group				ko:K06236	ko04151,ko04510,ko04512,ko04611,ko04926,ko04933,ko04974,ko05146,ko05165,map04151,map04510,map04512,map04611,map04926,map04933,map04974,map05146,map05165				ko00000,ko00001,ko00536,ko04516				Bacteria	1UMUJ@1239,42EFA@671232,4IU0F@91061,COG3468@1,COG3468@2	NA|NA|NA	MU	outer membrane autotransporter barrel domain protein
NHHNPPIF_01961	482234.SCAZ3_00305	0.0	2360.5	Bacteria													Bacteria	COG3087@1,COG3087@2	NA|NA|NA	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NHHNPPIF_01962	482234.SCAZ3_00310	1.2e-73	282.3	Bacteria				ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440				ko00000,ko00001,ko03029,ko03032,ko03400				Bacteria	COG0629@1,COG0629@2	NA|NA|NA	L	single-stranded DNA binding
NHHNPPIF_01963	482234.SCAZ3_00315	1.6e-189	668.7	Bacilli	nagZ		3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000				Bacteria	1TP63@1239,4HBDB@91061,COG1472@1,COG1472@2	NA|NA|NA	G	Belongs to the glycosyl hydrolase 3 family
NHHNPPIF_01965	1035189.HMPREF9954_1825	1.9e-13	81.6	Streptococcus infantis													Bacteria	1TWM4@1239,2DIZS@1,304EW@2,43GJS@68892,4I5EY@91061	NA|NA|NA		
NHHNPPIF_01966	482234.SCAZ3_00330	0.0	1947.9	Bacilli				ko:K03205	ko03070,map03070	M00333			ko00000,ko00001,ko00002,ko02044	3.A.7			Bacteria	1TPCF@1239,4H9ZN@91061,COG3505@1,COG3505@2	NA|NA|NA	U	COG3505 Type IV secretory pathway, VirD4 components
NHHNPPIF_01967	1035189.HMPREF9954_1823	2.8e-26	125.2	Streptococcus infantis													Bacteria	1TWK4@1239,2DIZ9@1,304EA@2,43GGZ@68892,4I5DS@91061	NA|NA|NA		
NHHNPPIF_01968	1035189.HMPREF9954_1822	1.4e-218	766.1	Streptococcus infantis													Bacteria	1TWJ4@1239,2DIYY@1,304DQ@2,43GE2@68892,4I5CM@91061	NA|NA|NA		
NHHNPPIF_01969	1035189.HMPREF9954_1821	7.5e-27	126.3	Streptococcus infantis													Bacteria	1TWKS@1239,2DIZK@1,304EN@2,43GIZ@68892,4I5EI@91061	NA|NA|NA	S	BRCA1 C Terminus (BRCT) domain
NHHNPPIF_01970	388919.SSA_0155	1.3e-13	82.4	Streptococcus sanguinis													Bacteria	1UACV@1239,1WS5P@1305,2AR9W@1,31GJT@2,4IKR3@91061	NA|NA|NA	S	Uncharacterized protein pXO2-11
NHHNPPIF_01971	1035189.HMPREF9954_1819	3e-84	318.2	Streptococcus infantis													Bacteria	1TWJ2@1239,2DIYX@1,304DP@2,43GDZ@68892,4I5CJ@91061	NA|NA|NA		
NHHNPPIF_01972	482234.SCAZ3_00360	0.0	1297.3	Bacilli	trsE												Bacteria	1W186@1239,4HA4T@91061,COG0433@1,COG0433@2	NA|NA|NA	S	COG0433 Predicted ATPase
NHHNPPIF_01973	997830.HMPREF1124_0864	1.7e-22	111.7	Streptococcus infantis													Bacteria	1TWNB@1239,2DKPM@1,30A8D@2,43GMF@68892,4I5G5@91061	NA|NA|NA		
NHHNPPIF_01974	1123311.KB904459_gene606	1.2e-231	808.9	Bacteria				ko:K02395					ko00000,ko02035				Bacteria	COG1705@1,COG1705@2	NA|NA|NA	NU	amidase activity
NHHNPPIF_01975	1035189.HMPREF9954_1815	2.9e-57	228.4	Streptococcus infantis													Bacteria	1TWJM@1239,2DIZ3@1,304E1@2,43GFK@68892,4I5D6@91061	NA|NA|NA		
NHHNPPIF_01976	482234.SCAZ3_00380	4e-150	537.3	Bacteria				ko:K03496					ko00000,ko03036,ko04812				Bacteria	COG1192@1,COG1192@2	NA|NA|NA	D	plasmid maintenance
NHHNPPIF_01977	997830.HMPREF1124_0868	4.6e-18	97.1	Streptococcus infantis													Bacteria	1TWMJ@1239,2DIZZ@1,304F3@2,43GKA@68892,4I5FB@91061	NA|NA|NA		
NHHNPPIF_01978	997830.HMPREF1124_0869	4e-28	131.0	Streptococcus infantis													Bacteria	1W6YV@1239,2DIDU@1,302XM@2,43GNG@68892,4I5GY@91061	NA|NA|NA	S	Replication initiator protein A (RepA) N-terminus
NHHNPPIF_01979	1035189.HMPREF9954_1812	5e-09	67.4	Streptococcus infantis													Bacteria	1TWKX@1239,2DIZN@1,304EQ@2,43GJB@68892,4I5EP@91061	NA|NA|NA		
NHHNPPIF_01980	482234.SCAZ3_00400	3e-259	900.6	Bacilli													Bacteria	1UZVH@1239,2BVJW@1,32QXP@2,4HFK6@91061	NA|NA|NA	S	Uncharacterised protein family (UPF0236)
NHHNPPIF_01981	1046629.Ssal_00974	2.4e-57	228.0	Bacilli	pepD			ko:K08659					ko00000,ko01000,ko01002				Bacteria	1TQ0F@1239,4HC3G@91061,COG4690@1,COG4690@2	NA|NA|NA	E	Dipeptidase
NHHNPPIF_01982	264199.stu0859	1.2e-86	325.9	Bacteria	XK27_10720												Bacteria	COG2339@1,COG2339@2	NA|NA|NA	D	peptidase activity
NHHNPPIF_01983	264199.stu0860	3.6e-293	1013.4	Bacilli	adcA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0007154,GO:0008150,GO:0008270,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0030288,GO:0030313,GO:0031667,GO:0031668,GO:0031669,GO:0031975,GO:0033554,GO:0034224,GO:0042221,GO:0042594,GO:0042597,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046686,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0120127		ko:K09815	ko02010,map02010	M00242			ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5			Bacteria	1TPG7@1239,4H9UN@91061,COG0803@1,COG0803@2,COG3443@1,COG3443@2	NA|NA|NA	P	Belongs to the bacterial solute-binding protein 9 family
NHHNPPIF_01984	663952.SDD27957_05960	1.7e-08	65.9	Streptococcus dysgalactiae group													Bacteria	1M9M6@119603,1TXBA@1239,2DJ70@1,304WJ@2,4I68X@91061	NA|NA|NA		
NHHNPPIF_01985	322159.STER_0898	1.5e-170	605.5	Firmicutes	yeiH												Bacteria	1TQYA@1239,COG2855@1,COG2855@2	NA|NA|NA	S	Membrane
NHHNPPIF_01986	904306.HMPREF9192_1840	1.6e-118	432.2	Bacilli	mur1			ko:K02395					ko00000,ko02035				Bacteria	1UYRM@1239,4HAU6@91061,COG1705@1,COG1705@2	NA|NA|NA	NU	muramidase
NHHNPPIF_01987	264199.stu1454	4.2e-20	103.6	Bacteria				ko:K07483					ko00000				Bacteria	COG2963@1,COG2963@2	NA|NA|NA	L	transposase activity
NHHNPPIF_01988	322159.STER_0901	4.5e-166	590.5	Bacilli	cpsY												Bacteria	1TP3E@1239,4HC5J@91061,COG0583@1,COG0583@2	NA|NA|NA	K	Transcriptional regulator
NHHNPPIF_01989	322159.STER_0903	0.0	1166.0	Bacilli	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931		R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002			iNJ661.Rv3436c,iSB619.SA_RS11245,iYO844.BSU01780	Bacteria	1TPGU@1239,4H9R4@91061,COG0449@1,COG0449@2	NA|NA|NA	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NHHNPPIF_01990	322159.STER_0904	6.1e-57	226.5	Bacilli	phnA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464		ko:K06193	ko01120,map01120				ko00000				Bacteria	1V6NA@1239,4HIKN@91061,COG2824@1,COG2824@2	NA|NA|NA	P	Alkylphosphonate utilization operon protein PhnA
NHHNPPIF_01991	264199.stu0875	5.3e-105	387.1	Bacilli	artQ			ko:K02029,ko:K02030,ko:K17073,ko:K17074	ko02010,map02010	M00236,M00589			ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.20			Bacteria	1V280@1239,4HGMH@91061,COG0765@1,COG0765@2	NA|NA|NA	P	ABC transporter (Permease
NHHNPPIF_01992	264199.stu0876	9.8e-112	409.5	Bacteria	glnQ		3.6.3.21	ko:K02028		M00236			ko00000,ko00002,ko01000,ko02000	3.A.1.3			Bacteria	COG1126@1,COG1126@2	NA|NA|NA	E	abc transporter atp-binding protein
NHHNPPIF_01993	322159.STER_0907	1.2e-157	562.4	Firmicutes	aatB			ko:K02029,ko:K02030		M00236			ko00000,ko00002,ko02000	3.A.1.3			Bacteria	1TQNR@1239,COG0834@1,COG0834@2	NA|NA|NA	ET	ABC transporter substrate-binding protein
NHHNPPIF_01994	904306.HMPREF9192_1830	2.1e-73	281.6	Bacilli	uvrX		2.7.7.7	ko:K02346,ko:K03502,ko:K14161					ko00000,ko01000,ko03400				Bacteria	1TP42@1239,4HA1P@91061,COG0389@1,COG0389@2	NA|NA|NA	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHHNPPIF_01995	264199.stu0879	1.9e-110	405.2	Bacilli	uvrX		2.7.7.7	ko:K02346,ko:K03502,ko:K14161					ko00000,ko01000,ko03400				Bacteria	1TP42@1239,4HA1P@91061,COG0389@1,COG0389@2	NA|NA|NA	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHHNPPIF_01996	435842.HMPREF0848_00769	2.1e-07	60.1	Firmicutes													Bacteria	1VFJD@1239,2E660@1,330UP@2	NA|NA|NA		
NHHNPPIF_01997	264199.stu0880	6.6e-62	243.0	Bacilli	adhP	GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0006081,GO:0006117,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009636,GO:0009987,GO:0010033,GO:0016491,GO:0016614,GO:0016616,GO:0033554,GO:0042221,GO:0042493,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0045471,GO:0046185,GO:0046187,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0097305,GO:1901575,GO:1901700	1.1.1.1	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220		R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000			iECP_1309.ECP_1480	Bacteria	1TP5B@1239,4HA9Z@91061,COG1064@1,COG1064@2	NA|NA|NA	C	alcohol dehydrogenase
NHHNPPIF_01998	904306.HMPREF9192_1827	6.1e-112	410.2	Bacilli	adhP	GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0006081,GO:0006117,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009636,GO:0009987,GO:0010033,GO:0016491,GO:0016614,GO:0016616,GO:0033554,GO:0042221,GO:0042493,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0045471,GO:0046185,GO:0046187,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0097305,GO:1901575,GO:1901700	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220		R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000			iECP_1309.ECP_1480	Bacteria	1TP5B@1239,4HA9Z@91061,COG1064@1,COG1064@2	NA|NA|NA	C	alcohol dehydrogenase
NHHNPPIF_02000	1116231.SMA_0980	3e-21	107.1	Bacilli													Bacteria	1W1ET@1239,2DY2G@1,347TK@2,4HYVW@91061	NA|NA|NA		
NHHNPPIF_02001	264199.stu0884	0.0	1798.1	Bacilli	res_1		3.1.21.5	ko:K01156					ko00000,ko01000,ko02048				Bacteria	1TRVK@1239,4HAVG@91061,COG3421@1,COG3421@2	NA|NA|NA	S	Type III restriction
NHHNPPIF_02002	264199.stu0885	0.0	1233.8	Bacilli	sthIM		2.1.1.72	ko:K07316					ko00000,ko01000,ko02048				Bacteria	1TR8A@1239,4HBP1@91061,COG2189@1,COG2189@2	NA|NA|NA	L	Adenine specific DNA methylase Mod
NHHNPPIF_02003	264199.stu0886	3.9e-303	1046.6	Bacilli	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.3.1.128,6.3.5.2	ko:K01951,ko:K03790	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002,ko03009			iJN746.PP_1032,iLJ478.TM1820,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833	Bacteria	1TPG8@1239,4HA7Q@91061,COG0518@1,COG0518@2,COG0519@1,COG0519@2	NA|NA|NA	F	Catalyzes the synthesis of GMP from XMP
NHHNPPIF_02004	322159.STER_0913	2e-126	458.4	Bacilli	gntR1			ko:K03710,ko:K11922					ko00000,ko03000				Bacteria	1UYBW@1239,4HDDG@91061,COG2188@1,COG2188@2	NA|NA|NA	K	transcriptional
NHHNPPIF_02005	264199.stu0888	1.1e-53	215.7	Bacilli	ylxM	GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772		ko:K09787					ko00000				Bacteria	1VEGP@1239,4HKK6@91061,COG2739@1,COG2739@2	NA|NA|NA	S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NHHNPPIF_02006	264199.stu0889	1.6e-272	944.9	Bacilli	ffh	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9			Bacteria	1TP06@1239,4H9T4@91061,COG0541@1,COG0541@2	NA|NA|NA	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NHHNPPIF_02007	264199.stu0890	3.1e-87	327.8	Bacilli	niaX	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K16788					ko00000,ko02000	2.A.88.5			Bacteria	1V4NF@1239,2A1RE@1,311D4@2,4HH6C@91061	NA|NA|NA		
NHHNPPIF_02008	264199.stu0891	6e-91	340.1	Bacilli	niaR			ko:K07105					ko00000				Bacteria	1V6EY@1239,4HGYB@91061,COG1827@1,COG1827@2	NA|NA|NA	S	small molecule binding protein (contains 3H domain)
NHHNPPIF_02009	264199.stu0892	8.1e-128	463.0	Bacilli													Bacteria	1V758@1239,4HIKZ@91061,COG1396@1,COG1396@2,COG2932@1,COG2932@2	NA|NA|NA	K	DNA-binding helix-turn-helix protein
NHHNPPIF_02010	264199.stu0893	1.2e-157	562.4	Bacilli	ylqF	GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840		ko:K14540					ko00000,ko03009				Bacteria	1TQGK@1239,4HA4D@91061,COG1161@1,COG1161@2	NA|NA|NA	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NHHNPPIF_02011	322159.STER_0920	5.9e-135	486.9	Bacilli	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030				ko00000,ko00001,ko01000,ko03032				Bacteria	1V1D6@1239,4HB7M@91061,COG0164@1,COG0164@2	NA|NA|NA	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHHNPPIF_02012	322159.STER_0921	4e-85	320.9	Firmicutes													Bacteria	1TRQ7@1239,COG1940@1,COG1940@2	NA|NA|NA	GK	ROK family
NHHNPPIF_02013	322159.STER_0921	1.6e-70	271.9	Firmicutes													Bacteria	1TRQ7@1239,COG1940@1,COG1940@2	NA|NA|NA	GK	ROK family
NHHNPPIF_02014	264199.stu0896	8.3e-159	566.2	Bacilli	dprA	GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496		ko:K04096					ko00000				Bacteria	1TPP7@1239,4HGWM@91061,COG0758@1,COG0758@2	NA|NA|NA	LU	DNA protecting protein DprA
NHHNPPIF_02015	322159.STER_0923	0.0	1323.1	Bacilli	topA		5.99.1.2	ko:K03168					ko00000,ko01000,ko03032,ko03400				Bacteria	1TPUS@1239,4HA6C@91061,COG0550@1,COG0550@2	NA|NA|NA	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NHHNPPIF_02016	322159.STER_0924	3.6e-154	550.8	Bacilli													Bacteria	1V2FW@1239,2DC01@1,2ZC51@2,4HG69@91061	NA|NA|NA	S	TraX protein
NHHNPPIF_02017	322159.STER_0925	2.7e-120	438.0	Firmicutes													Bacteria	1TQ0D@1239,COG0745@1,COG0745@2	NA|NA|NA	KT	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHHNPPIF_02018	264199.stu0902	1.9e-248	864.8	Bacilli													Bacteria	1TS1G@1239,4HEWT@91061,COG0642@1,COG2205@2	NA|NA|NA	T	PhoQ Sensor
NHHNPPIF_02019	322159.STER_0927	9.6e-258	895.6	Bacilli	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094					ko00000,ko01000,ko03016,ko03036				Bacteria	1TP67@1239,4HB27@91061,COG1206@1,COG1206@2	NA|NA|NA	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NHHNPPIF_02020	264199.stu0905	6.5e-78	296.6	Bacilli	XK27_05470												Bacteria	1TPDQ@1239,4HADW@91061,COG0620@1,COG0620@2	NA|NA|NA	E	Methionine synthase
NHHNPPIF_02021	904306.HMPREF9192_1810	9.3e-36	155.6	Bacilli	XK27_05470												Bacteria	1TPDQ@1239,4HADW@91061,COG0620@1,COG0620@2	NA|NA|NA	E	Methionine synthase
NHHNPPIF_02022	264199.stu0906	1.7e-75	288.5	Firmicutes	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131				Bacteria	1V44G@1239,COG0105@1,COG0105@2	NA|NA|NA	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NHHNPPIF_02023	322159.STER_0930	1.9e-46	191.4	Bacteria	pspE			ko:K03972					ko00000				Bacteria	COG0607@1,COG0607@2	NA|NA|NA	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NHHNPPIF_02024	264199.stu0909	6.8e-51	206.5	Bacilli													Bacteria	1TRQC@1239,4HD7P@91061,COG1028@1,COG1028@2	NA|NA|NA	IQ	Acetoin reductase
NHHNPPIF_02025	1114965.Spaf_0915	2.6e-45	187.6	Bacilli													Bacteria	1TRQC@1239,4HD7P@91061,COG1028@1,COG1028@2	NA|NA|NA	IQ	Acetoin reductase
NHHNPPIF_02027	264199.stu0911	0.0	1176.8	Bacilli	lepA			ko:K03596	ko05134,map05134				ko00000,ko00001				Bacteria	1TP0G@1239,4HASA@91061,COG0481@1,COG0481@2	NA|NA|NA	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NHHNPPIF_02031	264199.stu0916	1.1e-53	215.7	Bacteria				ko:K15773					ko00000,ko02048,ko03000				Bacteria	COG1813@1,COG1813@2	NA|NA|NA	K	peptidyl-tyrosine sulfation
NHHNPPIF_02032	264199.stu0917	1.6e-58	231.9	Bacilli	Z012_04635												Bacteria	1UZI0@1239,4HC2C@91061,COG1396@1,COG1396@2	NA|NA|NA	K	Transcriptional activator, Rgg GadR MutR family
NHHNPPIF_02033	322159.STER_0934	2e-55	221.5	Bacilli	Z012_04635												Bacteria	1UZI0@1239,4HC2C@91061,COG1396@1,COG1396@2	NA|NA|NA	K	Transcriptional activator, Rgg GadR MutR family
NHHNPPIF_02036	264199.stu0920	1.1e-212	745.7	Firmicutes	pqqE												Bacteria	1TR52@1239,COG0535@1,COG0535@2	NA|NA|NA	C	radical SAM domain protein
NHHNPPIF_02037	264199.stu0921	3.9e-136	490.7	Bacteria	speB		3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000				Bacteria	COG0010@1,COG0010@2	NA|NA|NA	E	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
NHHNPPIF_02038	1121864.OMO_01537	6.6e-61	241.5	Bacteria				ko:K08218	ko01501,map01501	M00628			ko00000,ko00001,ko00002,ko02000	2.A.1.25			Bacteria	COG0477@1,COG2814@2	NA|NA|NA	EGP	Major facilitator Superfamily
NHHNPPIF_02039	322159.STER_0940	0.0	1105.1	Bacilli	alsS		2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQE8@1239,4HAV1@91061,COG0028@1,COG0028@2	NA|NA|NA	EH	Belongs to the TPP enzyme family
NHHNPPIF_02040	435842.HMPREF0848_00743	5.9e-129	466.8	Bacilli	budA	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0047605	4.1.1.5	ko:K01575	ko00650,ko00660,map00650,map00660		R02948	RC00812	ko00000,ko00001,ko01000				Bacteria	1V4AH@1239,4HJ98@91061,COG3527@1,COG3527@2	NA|NA|NA	H	Belongs to the alpha-acetolactate decarboxylase family
NHHNPPIF_02041	322159.STER_0003	6.2e-168	596.7	Firmicutes				ko:K07485					ko00000				Bacteria	1TQ93@1239,COG3464@1,COG3464@2	NA|NA|NA	L	Transposase
NHHNPPIF_02042	435842.HMPREF0848_01721	3e-48	197.6	Bacilli				ko:K10947					ko00000,ko03000				Bacteria	1VIVQ@1239,4IR4R@91061,COG1695@1,COG1695@2	NA|NA|NA	K	transcriptional regulator, PadR family
NHHNPPIF_02043	435842.HMPREF0848_01720	9.6e-08	61.2	Bacilli	XK27_06920												Bacteria	1VBG6@1239,4HSRQ@91061,COG4709@1,COG4709@2	NA|NA|NA	S	Protein of unknown function (DUF1700)
NHHNPPIF_02044	904306.HMPREF9192_1905	9.1e-13	79.3	Bacilli	XK27_06920												Bacteria	1VBG6@1239,4HSRQ@91061,COG4709@1,COG4709@2	NA|NA|NA	S	Protein of unknown function (DUF1700)
NHHNPPIF_02045	264199.stu1992	1.3e-106	392.9	Bacilli													Bacteria	1VGGF@1239,4I0VY@91061,COG3595@1,COG3595@2	NA|NA|NA	S	Putative adhesin
NHHNPPIF_02046	322159.STER_1969	4e-158	565.5	Bacilli	XK27_06930			ko:K01421					ko00000				Bacteria	1TQ15@1239,4H9T9@91061,COG1511@1,COG1511@2	NA|NA|NA	V	domain protein
NHHNPPIF_02047	264199.stu1995	2.1e-94	351.7	Bacteria	XK27_06935												Bacteria	COG1309@1,COG1309@2	NA|NA|NA	K	transcriptional regulator
NHHNPPIF_02048	1046629.Ssal_00032	5.5e-11	72.4	Firmicutes	ypaA			ko:K08987					ko00000				Bacteria	1VAEU@1239,COG3759@1,COG3759@2	NA|NA|NA	M	Membrane
NHHNPPIF_02049	1123318.KB904633_gene1270	2e-07	61.2	Bacilli													Bacteria	1W3FT@1239,2914P@1,2ZNS1@2,4I23Q@91061	NA|NA|NA		
NHHNPPIF_02050	264199.stu1997	4.9e-108	397.1	Bacilli	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112		ko:K02986	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1TR0J@1239,4HAC9@91061,COG0522@1,COG0522@2	NA|NA|NA	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NHHNPPIF_02051	264199.stu1998	8.2e-48	196.1	Bacilli	veg												Bacteria	1VPZY@1239,4HSFF@91061,COG4466@1,COG4466@2	NA|NA|NA	S	Biofilm formation stimulator VEG
NHHNPPIF_02052	322159.STER_1975	1.5e-245	855.1	Bacilli	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112				ko00000,ko00001,ko01000,ko03032				Bacteria	1TPCT@1239,4H9Y8@91061,COG0305@1,COG0305@2	NA|NA|NA	L	Participates in initiation and elongation during chromosome replication
NHHNPPIF_02053	435842.HMPREF0848_01711	8.5e-73	279.6	Bacilli	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02939	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V6QG@1239,4HIKJ@91061,COG0359@1,COG0359@2	NA|NA|NA	J	binds to the 23S rRNA
NHHNPPIF_02054	322159.STER_1977	0.0	1255.0	Bacilli	yybT												Bacteria	1TPGP@1239,4HBVH@91061,COG3887@1,COG3887@2	NA|NA|NA	T	signaling protein consisting of a modified GGDEF domain and a DHH domain
NHHNPPIF_02055	435842.HMPREF0848_01709	0.0	1224.2	Bacilli	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363		ko:K03495			R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036				Bacteria	1TQ4B@1239,4HA6S@91061,COG0445@1,COG0445@2	NA|NA|NA	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NHHNPPIF_02056	435842.HMPREF0848_01708	3.7e-76	290.8	Bacilli													Bacteria	1VAVP@1239,4HSPC@91061,COG1051@1,COG1051@2	NA|NA|NA	F	NUDIX domain
NHHNPPIF_02057	1046629.Ssal_00023	3.2e-214	750.7	Bacilli	mnmA	GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.8.1.13	ko:K00566	ko04122,map04122		R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016				Bacteria	1TPIZ@1239,4HBJ6@91061,COG0482@1,COG0482@2	NA|NA|NA	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NHHNPPIF_02058	322159.STER_1980	1.2e-300	1038.5	Bacilli													Bacteria	1V0XZ@1239,4HEBN@91061,COG4485@1,COG4485@2	NA|NA|NA	S	Bacterial membrane protein, YfhO
NHHNPPIF_02059	322159.STER_1981	1.7e-63	249.2	Bacilli	isaA			ko:K21687					ko00000		GH23		Bacteria	1VGPA@1239,4HP1I@91061,COG0741@1,COG0741@2	NA|NA|NA	M	Immunodominant staphylococcal antigen A
NHHNPPIF_02060	264199.stu2006	3.9e-80	304.3	Bacilli	lytE												Bacteria	1VA10@1239,4HMUH@91061,COG1388@1,COG1388@2	NA|NA|NA	M	LysM domain protein
NHHNPPIF_02061	264199.stu2007	1.6e-135	488.8	Bacilli	ecfT	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656		ko:K02008,ko:K16783,ko:K16785	ko02010,map02010	M00245,M00246,M00581,M00582			ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35			Bacteria	1TQ0E@1239,4H9VT@91061,COG0619@1,COG0619@2	NA|NA|NA	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHHNPPIF_02062	264199.stu2008	2.6e-152	544.7	Bacilli	ecfA2	GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008144,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032217,GO:0032218,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035461,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0097159,GO:0097367,GO:0098656,GO:1901265,GO:1901363	3.6.3.55	ko:K02068,ko:K06857,ko:K16784,ko:K16786,ko:K16787	ko02010,map02010	M00186,M00211,M00581,M00582	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35,3.A.1.6.2,3.A.1.6.4			Bacteria	1TPH8@1239,4HA7T@91061,COG1122@1,COG1122@2	NA|NA|NA	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHHNPPIF_02063	322159.STER_1985	6.3e-151	540.0	Bacilli	ecfA1	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656		ko:K16784,ko:K16786,ko:K16787	ko02010,map02010	M00581,M00582			ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35			Bacteria	1TPH8@1239,4H9R8@91061,COG1122@1,COG1122@2	NA|NA|NA	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHHNPPIF_02064	264199.stu2010	4.1e-90	337.4	Bacilli	pgsA	GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100		R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000			iSB619.SA_RS06365	Bacteria	1V6PJ@1239,4HCEX@91061,COG0558@1,COG0558@2	NA|NA|NA	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NHHNPPIF_02065	322159.STER_1987	7e-137	493.4	Bacteria	ymfM			ko:K15539					ko00000				Bacteria	COG1426@1,COG1426@2	NA|NA|NA	S	sequence-specific DNA binding
NHHNPPIF_02066	264199.stu2012	4.7e-238	830.1	Bacilli	ymfH			ko:K07263					ko00000,ko01000,ko01002				Bacteria	1TP5I@1239,4H9YG@91061,COG0612@1,COG0612@2	NA|NA|NA	S	Peptidase M16
NHHNPPIF_02067	322159.STER_1989	4.5e-233	813.5	Bacilli	ymfF												Bacteria	1TPN6@1239,4H9P5@91061,COG0612@1,COG0612@2	NA|NA|NA	S	Peptidase M16
NHHNPPIF_02068	264199.stu2014	3.6e-45	187.6	Bacilli	yaaA	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576		ko:K14761					ko00000,ko03009				Bacteria	1VKF4@1239,4HRX5@91061,COG2501@1,COG2501@2	NA|NA|NA	S	S4 domain protein YaaA
NHHNPPIF_02069	322159.STER_1991	1.5e-203	715.3	Bacilli	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576		ko:K03629	ko03440,map03440				ko00000,ko00001,ko03400				Bacteria	1TP9U@1239,4HA0W@91061,COG1195@1,COG1195@2	NA|NA|NA	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NHHNPPIF_02070	322159.STER_1992	4.7e-274	949.9	Bacilli	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147			iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027	Bacteria	1TNZ1@1239,4H9V3@91061,COG0516@1,COG0516@2,COG0517@1,COG0517@2	NA|NA|NA	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NHHNPPIF_02071	264199.stu2018	6.3e-193	679.9	Bacilli	trpS	GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016				Bacteria	1TPY7@1239,4HA1K@91061,COG0180@1,COG0180@2	NA|NA|NA	J	Tryptophanyl-tRNA synthetase
NHHNPPIF_02072	322159.STER_1994	3.4e-124	451.1	Bacilli	yvjA												Bacteria	1TR9J@1239,4H9N6@91061,COG1284@1,COG1284@2	NA|NA|NA	S	membrane
NHHNPPIF_02073	264199.stu2020	6.7e-306	1055.8	Bacilli	ybiT	GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0050896		ko:K06158					ko00000,ko03012				Bacteria	1TPW0@1239,4HATH@91061,COG0488@1,COG0488@2	NA|NA|NA	S	abc transporter atp-binding protein
NHHNPPIF_02074	264199.stu2021	0.0	1660.2	Bacilli	XK27_10405												Bacteria	1TRR1@1239,4HCR9@91061,COG4485@1,COG4485@2	NA|NA|NA	S	Bacterial membrane protein YfhO
NHHNPPIF_02078	264199.stu2022	1.8e-119	435.3	Firmicutes	yoaK												Bacteria	1V1VQ@1239,COG3619@1,COG3619@2	NA|NA|NA	S	Psort location CytoplasmicMembrane, score
NHHNPPIF_02079	264199.stu2023	7.4e-86	323.2	Bacilli	rlmH		2.1.1.177	ko:K00783					ko00000,ko01000,ko03009				Bacteria	1V3JM@1239,4HFP8@91061,COG1576@1,COG1576@2	NA|NA|NA	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NHHNPPIF_02080	264199.stu2024	5.6e-196	690.3	Bacilli	htrA	GO:0008150,GO:0009266,GO:0009628,GO:0050896	3.4.21.107	ko:K04691,ko:K04771	ko01503,ko02020,map01503,map02020	M00728			ko00000,ko00001,ko00002,ko01000,ko01002,ko03110				Bacteria	1TRM8@1239,4HA31@91061,COG0265@1,COG0265@2	NA|NA|NA	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
NHHNPPIF_02081	322159.STER_2003	1.4e-133	482.3	Bacilli	parB			ko:K03497					ko00000,ko03000,ko03036,ko04812				Bacteria	1TQ2B@1239,4H9TB@91061,COG1475@1,COG1475@2	NA|NA|NA	K	Belongs to the ParB family
NHHNPPIF_02082	264199.stu0001	4.8e-257	893.3	Bacilli	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837		ko:K02313	ko02020,ko04112,map02020,map04112				ko00000,ko00001,ko03032,ko03036				Bacteria	1TPV7@1239,4H9MW@91061,COG0593@1,COG0593@2	NA|NA|NA	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NHHNPPIF_02083	322159.STER_0002	8.2e-202	709.5	Bacilli	dnaN		2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1TQ7J@1239,4H9TF@91061,COG0592@1,COG0592@2	NA|NA|NA	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NHHNPPIF_02084	1046629.Ssal_02164	4.1e-29	133.3	Bacilli	yyzM												Bacteria	1VEQ7@1239,4HNHU@91061,COG4481@1,COG4481@2	NA|NA|NA	S	Protein conserved in bacteria
NHHNPPIF_02085	264199.stu0004	8.6e-204	716.1	Bacilli	ychF	GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772		ko:K06942					ko00000,ko03009				Bacteria	1TPRK@1239,4H9SQ@91061,COG0012@1,COG0012@2	NA|NA|NA	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NHHNPPIF_02086	264199.stu0005	1.4e-104	385.6	Bacilli	pth	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101	3.1.1.29	ko:K01056					ko00000,ko01000,ko03012				Bacteria	1V3NB@1239,4HH2Z@91061,COG0193@1,COG0193@2	NA|NA|NA	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NHHNPPIF_02087	322159.STER_0007	0.0	2258.0	Bacilli	mfd			ko:K03723	ko03420,map03420				ko00000,ko00001,ko01000,ko03400				Bacteria	1TPF1@1239,4H9NB@91061,COG1197@1,COG1197@2	NA|NA|NA	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NHHNPPIF_02088	264199.stu0007	1.7e-39	168.3	Bacilli	yabO	GO:0008150,GO:0040007											Bacteria	1VEI5@1239,4HKJJ@91061,COG1188@1,COG1188@2	NA|NA|NA	J	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NHHNPPIF_02089	322159.STER_0009	2.7e-61	241.1	Bacilli	divIC			ko:K05589,ko:K13052					ko00000,ko03036				Bacteria	1VKC5@1239,4HR53@91061,COG2919@1,COG2919@2	NA|NA|NA	D	Septum formation initiator
NHHNPPIF_02091	322159.STER_0011	1.5e-239	835.1	Bacilli	XK27_09285		3.5.2.6	ko:K01467,ko:K17836	ko00311,ko01130,ko01501,ko02020,map00311,map01130,map01501,map02020	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504				Bacteria	1VGXR@1239,4IPWW@91061,COG2367@1,COG2367@2	NA|NA|NA	V	Beta-lactamase enzyme family
NHHNPPIF_02092	264199.stu0010	1.2e-238	832.0	Bacilli	tilS		2.4.2.8,6.3.4.19	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110		R01132,R01229,R02142,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016				Bacteria	1TPXP@1239,4H9ZM@91061,COG0037@1,COG0037@2	NA|NA|NA	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NHHNPPIF_02093	264199.stu0011	3.4e-97	360.9	Bacilli	hpt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.2.8,6.3.4.19	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110		R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000,ko03016				Bacteria	1V1C9@1239,4HFZ2@91061,COG0634@1,COG0634@2	NA|NA|NA	F	Belongs to the purine pyrimidine phosphoribosyltransferase family
NHHNPPIF_02094	322159.STER_0014	0.0	1253.0	Bacilli	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575		ko:K03798		M00742			ko00000,ko00002,ko01000,ko01002,ko03110				Bacteria	1TPTV@1239,4HAJB@91061,COG0465@1,COG0465@2	NA|NA|NA	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NHHNPPIF_02095	322159.STER_0015	1.7e-162	578.6	Firmicutes				ko:K07485					ko00000				Bacteria	1TQ93@1239,COG3464@1,COG3464@2	NA|NA|NA	L	Transposase
NHHNPPIF_02096	1198676.SMUGS5_00840	2.6e-10	69.7	Firmicutes													Bacteria	1VP0T@1239,2EG8N@1,33A0G@2	NA|NA|NA		
NHHNPPIF_02099	1123309.AQYB01000022_gene40	1.9e-07	60.1	Bacilli													Bacteria	1VNP3@1239,2ED1A@1,336Y8@2,4HRCX@91061	NA|NA|NA		
NHHNPPIF_02104	322159.STER_0095	0.0	2907.5	Bacilli	polC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.7.7	ko:K02342,ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400				Bacteria	1TPAG@1239,4H9RF@91061,COG2176@1,COG2176@2	NA|NA|NA	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHHNPPIF_02105	264199.stu0063	2.8e-235	820.8	Bacilli	pepS			ko:K19689					ko00000,ko01000,ko01002				Bacteria	1TP65@1239,4H9W8@91061,COG2309@1,COG2309@2	NA|NA|NA	E	COG2309 Leucyl aminopeptidase (aminopeptidase T)
NHHNPPIF_02106	264199.stu0064	1.6e-35	154.8	Bacteria	XK27_02060												Bacteria	COG2261@1,COG2261@2	NA|NA|NA	S	Transglycosylase associated protein
NHHNPPIF_02107	264199.stu0065	4.4e-55	220.3	Bacteria	badR			ko:K15973					ko00000,ko03000				Bacteria	COG1846@1,COG1846@2	NA|NA|NA	K	DNA-binding transcription factor activity
NHHNPPIF_02108	264199.stu0066	6e-97	360.1	Firmicutes				ko:K19784					ko00000				Bacteria	1VAI8@1239,COG0431@1,COG0431@2	NA|NA|NA	S	reductase
NHHNPPIF_02109	322159.STER_0101	1.2e-32	145.2	Firmicutes				ko:K07497					ko00000				Bacteria	1TQQY@1239,COG2801@1,COG2801@2	NA|NA|NA	L	Integrase core domain protein
NHHNPPIF_02111	1116231.SMA_2094	1.5e-172	612.1	Bacilli	yocD		3.4.17.13	ko:K01297					ko00000,ko01000,ko01002,ko01011				Bacteria	1TRBB@1239,4HB1P@91061,COG1619@1,COG1619@2	NA|NA|NA	V	proteins, homologs of microcin C7 resistance protein MccF
NHHNPPIF_02113	264199.stu0073	3.7e-137	494.2	Bacilli	rpsB	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02967	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1TPNA@1239,4H9N5@91061,COG0052@1,COG0052@2	NA|NA|NA	J	Belongs to the universal ribosomal protein uS2 family
NHHNPPIF_02114	264199.stu0074	3e-182	644.4	Bacilli	tsf	GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065		ko:K02357					ko00000,ko03012,ko03029				Bacteria	1TPFJ@1239,4HBDV@91061,COG0264@1,COG0264@2	NA|NA|NA	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NHHNPPIF_02115	322159.STER_0107	9.3e-83	312.8	Bacilli													Bacteria	1V3UW@1239,4HPN6@91061,COG2426@1,COG2426@2	NA|NA|NA	S	Putative small multi-drug export protein
NHHNPPIF_02116	264199.stu0076	6.2e-76	290.0	Bacilli	ctsR	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170		ko:K03708					ko00000,ko03000				Bacteria	1VAXT@1239,4HIFT@91061,COG4463@1,COG4463@2	NA|NA|NA	K	Belongs to the CtsR family
NHHNPPIF_02117	264199.stu0077	0.0	1551.2	Bacilli	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170		ko:K03696	ko01100,map01100				ko00000,ko03110				Bacteria	1TPMU@1239,4HACY@91061,COG0542@1,COG0542@2	NA|NA|NA	O	Belongs to the ClpA ClpB family
NHHNPPIF_02118	264199.stu0078	5.6e-129	467.2	Bacilli	dacA	GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100				ko00000,ko00001,ko01000,ko01002,ko01011				Bacteria	1TQN0@1239,4HBD4@91061,COG1686@1,COG1686@2	NA|NA|NA	M	Belongs to the peptidase S11 family
NHHNPPIF_02119	904306.HMPREF9192_0524	3.9e-59	234.2	Bacilli	dacA	GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100				ko00000,ko00001,ko01000,ko01002,ko01011				Bacteria	1TQN0@1239,4HBD4@91061,COG1686@1,COG1686@2	NA|NA|NA	M	Belongs to the peptidase S11 family
NHHNPPIF_02120	322159.STER_0113	2.1e-230	804.7	Bacilli	dacA	GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100				ko00000,ko00001,ko01000,ko01002,ko01011				Bacteria	1TQN0@1239,4HBD4@91061,COG1686@1,COG1686@2	NA|NA|NA	M	Belongs to the peptidase S11 family
NHHNPPIF_02121	264199.stu0081	0.0	1352.4	Bacilli	pnp	GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019				Bacteria	1TQDW@1239,4H9Z3@91061,COG1185@1,COG1185@2	NA|NA|NA	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NHHNPPIF_02122	322159.STER_0115	5e-142	510.4	Bacilli													Bacteria	1VY65@1239,2F67I@1,33YRI@2,4HXHY@91061	NA|NA|NA	S	SseB protein N-terminal domain
NHHNPPIF_02123	264199.stu0083	1.1e-112	412.5	Bacilli	cysE		2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000				Bacteria	1TR42@1239,4HAKS@91061,COG1045@1,COG1045@2	NA|NA|NA	E	serine acetyltransferase
NHHNPPIF_02124	264199.stu0084	6.6e-259	899.4	Bacilli	cysS	GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016			iECUMN_1333.ECUMN_0566,iJN746.PP_2905	Bacteria	1TP9D@1239,4HA6D@91061,COG0215@1,COG0215@2	NA|NA|NA	J	Belongs to the class-I aminoacyl-tRNA synthetase family
NHHNPPIF_02125	264199.stu0085	6.1e-67	260.0	Bacilli	mrnC	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360		ko:K11145					ko00000,ko01000,ko03009				Bacteria	1VA5V@1239,4HIM3@91061,COG1939@1,COG1939@2	NA|NA|NA	J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NHHNPPIF_02128	264199.stu0088	1.1e-133	482.6	Bacilli	trmH	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218,ko:K03437,ko:K12952					ko00000,ko01000,ko03009,ko03016	3.A.3.23			Bacteria	1TP9G@1239,4HBBI@91061,COG0566@1,COG0566@2	NA|NA|NA	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHHNPPIF_02129	264199.stu0089	1.6e-91	342.0	Bacilli	yacP			ko:K06962					ko00000				Bacteria	1V9XR@1239,4HFW4@91061,COG3688@1,COG3688@2	NA|NA|NA	S	RNA-binding protein containing a PIN domain
NHHNPPIF_02130	264199.stu0090	9.8e-155	552.7	Bacilli	degV												Bacteria	1TQDI@1239,4HAYQ@91061,COG1307@1,COG1307@2	NA|NA|NA	S	DegV family
NHHNPPIF_02132	411460.RUMTOR_00063	4.7e-32	144.4	Clostridia													Bacteria	1VK84@1239,24UEE@186801,COG1396@1,COG1396@2	NA|NA|NA	K	helix-turn-helix
NHHNPPIF_02133	264199.stu0092	4.8e-179	633.6	Bacilli	panE		1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000				Bacteria	1TSZ1@1239,4HB4T@91061,COG1893@1,COG1893@2	NA|NA|NA	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NHHNPPIF_02134	1046629.Ssal_02077	2e-79	301.6	Bacilli	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113		ko:K02871	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V3HX@1239,4HG0I@91061,COG0102@1,COG0102@2	NA|NA|NA	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NHHNPPIF_02135	264199.stu0094	2.8e-64	251.1	Bacilli	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02996	ko03010,map03010	M00178,M00179			br01610,ko00000,ko00001,ko00002,ko03011				Bacteria	1V3MQ@1239,4HH3B@91061,COG0103@1,COG0103@2	NA|NA|NA	J	Belongs to the universal ribosomal protein uS9 family
NHHNPPIF_02136	469609.HMPREF0847_00371	3.1e-223	780.8	Bacilli	int2												Bacteria	1TRCD@1239,4HDUS@91061,COG0582@1,COG0582@2	NA|NA|NA	L	Belongs to the 'phage' integrase family
NHHNPPIF_02137	469609.HMPREF0847_00372	4.9e-41	173.3	Bacilli													Bacteria	1VQRI@1239,2DS5K@1,33ENA@2,4HSSZ@91061	NA|NA|NA	S	Helix-turn-helix domain
NHHNPPIF_02138	469609.HMPREF0847_00373	4.1e-200	703.7	Bacilli				ko:K07467					ko00000				Bacteria	1V0X4@1239,4HF5X@91061,COG2946@1,COG2946@2	NA|NA|NA	L	Replication initiation factor
NHHNPPIF_02139	585204.SMSK597_1428	2.6e-36	158.3	Streptococcus mitis													Bacteria	1U4K6@1239,2DKDH@1,2TQ0T@28037,3097S@2,4IEBY@91061	NA|NA|NA		
NHHNPPIF_02140	997830.HMPREF1124_0514	1e-06	60.1	Streptococcus infantis													Bacteria	1TWJP@1239,2DIZ4@1,304E2@2,43GFM@68892,4I5D7@91061	NA|NA|NA		
NHHNPPIF_02141	469609.HMPREF0847_00376	3.2e-101	374.4	Firmicutes													Bacteria	1VKX5@1239,COG1396@1,COG1396@2	NA|NA|NA	K	DNA-binding helix-turn-helix protein
NHHNPPIF_02142	469609.HMPREF0847_00377	8.4e-38	162.5	Bacilli				ko:K20373	ko02024,map02024				ko00000,ko00001,ko03000				Bacteria	1VBRX@1239,4HMPG@91061,COG1396@1,COG1396@2	NA|NA|NA	K	Transcriptional activator, Rgg GadR MutR family
NHHNPPIF_02143	469609.HMPREF0847_00377	8.8e-88	329.7	Bacilli				ko:K20373	ko02024,map02024				ko00000,ko00001,ko03000				Bacteria	1VBRX@1239,4HMPG@91061,COG1396@1,COG1396@2	NA|NA|NA	K	Transcriptional activator, Rgg GadR MutR family
NHHNPPIF_02147	469609.HMPREF0847_00380	9.7e-155	552.7	Bacilli				ko:K01990		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1TPZR@1239,4HUQD@91061,COG1131@1,COG1131@2	NA|NA|NA	V	AAA domain, putative AbiEii toxin, Type IV TA system
NHHNPPIF_02148	1545701.LACWKB10_1400	2.5e-70	271.9	Lactobacillaceae													Bacteria	1U7PC@1239,29Q8I@1,30B7J@2,3F9Z8@33958,4IHKP@91061	NA|NA|NA	S	ABC-2 family transporter protein
NHHNPPIF_02149	1545701.LACWKB10_1399	2.8e-13	80.5	Lactobacillaceae													Bacteria	1U8A1@1239,2BA4E@1,323IA@2,3FARB@33958,4II7Z@91061	NA|NA|NA		
NHHNPPIF_02150	904306.HMPREF9192_0491	9.1e-223	779.2	Bacilli	capA			ko:K07282					ko00000				Bacteria	1UZW4@1239,4HBC3@91061,COG2843@1,COG2843@2	NA|NA|NA	M	Bacterial capsule synthesis protein
NHHNPPIF_02151	264199.stu0112	1.4e-38	165.2	Bacilli	gcvR			ko:K07166					ko00000				Bacteria	1VENW@1239,4HNJ4@91061,COG3830@1,COG3830@2	NA|NA|NA	T	UPF0237 protein
NHHNPPIF_02152	264199.stu0113	8.7e-243	845.9	Bacilli	XK27_08635			ko:K09157					ko00000				Bacteria	1TQG8@1239,4HBTU@91061,COG2848@1,COG2848@2	NA|NA|NA	S	UPF0210 protein
NHHNPPIF_02153	322159.STER_0158	1.5e-129	468.8	Bacilli	ais												Bacteria	1VDCB@1239,4HJ9X@91061,COG0406@1,COG0406@2	NA|NA|NA	G	Phosphoglycerate mutase
NHHNPPIF_02154	264199.stu0116	1.3e-137	495.7	Bacilli	vanY		3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651			ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504				Bacteria	1V1F7@1239,4HBR1@91061,COG1876@1,COG1876@2	NA|NA|NA	M	D-alanyl-D-alanine carboxypeptidase
NHHNPPIF_02155	264199.stu0117	1.4e-99	369.0	Bacteria	acmA		3.2.1.17	ko:K01185,ko:K02395					ko00000,ko01000,ko02035				Bacteria	COG1705@1,COG1705@2	NA|NA|NA	NU	amidase activity
NHHNPPIF_02156	264199.stu0118	5.4e-195	686.8	Bacilli	hrcA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141		ko:K03705					ko00000,ko03000				Bacteria	1TQP7@1239,4HAX5@91061,COG1420@1,COG1420@2	NA|NA|NA	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NHHNPPIF_02157	322159.STER_0162	3.6e-67	261.2	Bacilli	grpE	GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009628,GO:0009986,GO:0009987,GO:0009991,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030246,GO:0030247,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071496,GO:0071840,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065		ko:K03687					ko00000,ko03029,ko03110				Bacteria	1V6G2@1239,4HIRK@91061,COG0576@1,COG0576@2	NA|NA|NA	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NHHNPPIF_02158	322159.STER_0163	4.6e-287	993.4	Bacilli	dnaK	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065		ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152				ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1			Bacteria	1TP1J@1239,4HA9S@91061,COG0443@1,COG0443@2	NA|NA|NA	O	Heat shock 70 kDa protein
NHHNPPIF_02159	322159.STER_0164	4.5e-184	650.6	Bacilli	dnaJ			ko:K03686					ko00000,ko03029,ko03110				Bacteria	1TP00@1239,4H9KA@91061,COG0484@1,COG0484@2	NA|NA|NA	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NHHNPPIF_02160	264199.stu0122	3.6e-137	494.2	Bacilli	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173					ko00000,ko01000,ko03016				Bacteria	1TQUY@1239,4HCFI@91061,COG0101@1,COG0101@2	NA|NA|NA	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NHHNPPIF_02161	264199.stu0123	3.1e-136	491.1	Bacilli	thiD		2.7.1.35,2.7.1.49,2.7.4.7	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	M00127	R00174,R01909,R02493,R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQ4A@1239,4H9PP@91061,COG0351@1,COG0351@2	NA|NA|NA	H	phosphomethylpyrimidine kinase
NHHNPPIF_02162	1046629.Ssal_02049	9.6e-72	276.2	Bacilli	hmpT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944											Bacteria	1VBBN@1239,4HNM0@91061,COG4720@1,COG4720@2	NA|NA|NA	S	cog cog4720
NHHNPPIF_02164	862971.SANR_0567	6.7e-26	122.9	Streptococcus anginosus group													Bacteria	1TVYK@1239,2DITH@1,3043M@2,42EF9@671232,4I4KQ@91061	NA|NA|NA	S	Bacteriocin class II with double-glycine leader peptide
NHHNPPIF_02165	322159.STER_1649	7.4e-135	486.5	Bacteria	agrA			ko:K07707	ko02020,ko02024,map02020,map02024	M00495			ko00000,ko00001,ko00002,ko02022				Bacteria	COG3279@1,COG3279@2	NA|NA|NA	KT	phosphorelay signal transduction system
NHHNPPIF_02166	322159.STER_1650	9.9e-239	832.4	Bacteria	blpH		2.7.13.3	ko:K07706	ko02020,ko02024,map02020,map02024	M00495			ko00000,ko00001,ko00002,ko01000,ko01001,ko02022				Bacteria	COG3290@1,COG3290@2	NA|NA|NA	T	protein histidine kinase activity
NHHNPPIF_02168	322159.STER_1652	7.3e-237	826.2	Bacilli	mesE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944		ko:K20345	ko02024,map02024				ko00000,ko00001,ko02000	3.A.1.112,8.A.1			Bacteria	1V5C8@1239,4HHKB@91061,COG0845@1,COG0845@2	NA|NA|NA	M	Transport protein ComB
NHHNPPIF_02169	264199.stu1691	0.0	1374.8	Bacilli	comA			ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024				ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.21			Bacteria	1V77J@1239,4HAX2@91061,COG2274@1,COG2274@2	NA|NA|NA	V	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NHHNPPIF_02170	264199.stu1693	0.0	1084.7	Bacilli	mdlB	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008144,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0031224,GO:0032553,GO:0032555,GO:0032559,GO:0033036,GO:0034040,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363		ko:K06147,ko:K18890	ko02010,map02010	M00707			ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21			Bacteria	1TP0B@1239,4HA3S@91061,COG1132@1,COG1132@2	NA|NA|NA	V	abc transporter atp-binding protein
NHHNPPIF_02171	264199.stu1694	0.0	1111.3	Bacilli	mdlA	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016021,GO:0017076,GO:0030554,GO:0031224,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363		ko:K06148,ko:K18889	ko02010,map02010	M00707			ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.106.13,3.A.1.106.5			Bacteria	1TP0B@1239,4HA3S@91061,COG1132@1,COG1132@2	NA|NA|NA	V	abc transporter atp-binding protein
NHHNPPIF_02173	264199.stu1695	1.7e-93	348.6	Bacilli	XK27_09885												Bacteria	1VKIA@1239,4HQZW@91061,COG4767@1,COG4767@2	NA|NA|NA	V	Glycopeptide antibiotics resistance protein
NHHNPPIF_02174	322159.STER_1660	3e-223	780.8	Bacilli	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941					ko00000,ko01000,ko03009				Bacteria	1TPVF@1239,4H9NU@91061,COG0820@1,COG0820@2	NA|NA|NA	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NHHNPPIF_02175	322159.STER_1661	2.4e-66	258.8	Bacilli	yutD												Bacteria	1VA85@1239,4HKF7@91061,COG4470@1,COG4470@2	NA|NA|NA	J	protein conserved in bacteria
NHHNPPIF_02176	322159.STER_1662	5.3e-267	926.4	Bacilli	yunD		3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110		R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000				Bacteria	1TQCW@1239,4HAUC@91061,COG0737@1,COG0737@2	NA|NA|NA	F	Belongs to the 5'-nucleotidase family
NHHNPPIF_02178	322159.STER_1664	1.4e-221	775.4	Bacilli	cshB	GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363	3.6.4.13	ko:K05592,ko:K18692	ko03018,map03018				ko00000,ko00001,ko01000,ko03009,ko03019				Bacteria	1TPAP@1239,4HA98@91061,COG0513@1,COG0513@2	NA|NA|NA	JKL	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NHHNPPIF_02179	322159.STER_1665	6.3e-185	653.3	Bacilli	mraY	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502		R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146		iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105	Bacteria	1TP8W@1239,4H9TP@91061,COG0472@1,COG0472@2	NA|NA|NA	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NHHNPPIF_02180	322159.STER_1666	0.0	1455.7	Bacilli	ftsI	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681	3.4.16.4	ko:K03587,ko:K08384,ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501				ko00000,ko00001,ko01000,ko01011,ko03036			iSSON_1240.SSON_0092	Bacteria	1TP93@1239,4H9VQ@91061,COG0768@1,COG0768@2	NA|NA|NA	M	penicillin-binding protein
NHHNPPIF_02181	322159.STER_1667	4.3e-47	193.7	Bacilli	ftsL												Bacteria	1VCE5@1239,4HM4W@91061,COG4839@1,COG4839@2	NA|NA|NA	D	cell division protein FtsL
NHHNPPIF_02182	264199.stu1703	1.6e-175	622.1	Bacilli	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438					ko00000,ko01000,ko03009				Bacteria	1TNZV@1239,4H9U2@91061,COG0275@1,COG0275@2	NA|NA|NA	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NHHNPPIF_02183	264199.stu1704	1.6e-65	255.4	Bacilli													Bacteria	1W5UA@1239,2DDKD@1,2ZIF1@2,4HZND@91061	NA|NA|NA		
NHHNPPIF_02184	264199.stu1704	7.4e-27	125.9	Bacilli													Bacteria	1W5UA@1239,2DDKD@1,2ZIF1@2,4HZND@91061	NA|NA|NA		
NHHNPPIF_02185	264199.stu1704	7.5e-30	136.7	Bacilli													Bacteria	1W5UA@1239,2DDKD@1,2ZIF1@2,4HZND@91061	NA|NA|NA		
NHHNPPIF_02186	1046629.Ssal_00333	8.7e-33	146.4	Bacilli	yhaI												Bacteria	1V90R@1239,4HQ7Q@91061,COG3152@1,COG3152@2	NA|NA|NA	J	Protein of unknown function (DUF805)
NHHNPPIF_02187	435842.HMPREF0848_01480	4.5e-18	97.1	Bacteria													Bacteria	COG1196@1,COG1196@2	NA|NA|NA	D	nuclear chromosome segregation
NHHNPPIF_02188	322159.STER_1675	2e-225	788.1	Bacilli	proA	GO:0003674,GO:0003824,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000			iB21_1397.B21_00243,iECBD_1354.ECBD_3376,iECB_1328.ECB_00240,iECD_1391.ECD_00240,iLJ478.TM0293,iYL1228.KPN_00280,iYO844.BSU13130	Bacteria	1TQ9V@1239,4HB7B@91061,COG0014@1,COG0014@2	NA|NA|NA	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NHHNPPIF_02189	904306.HMPREF9192_0659	2.6e-141	508.1	Bacilli	proB	GO:0003674,GO:0003824,GO:0004349,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016772,GO:0016774,GO:0016903,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000				Bacteria	1TPG6@1239,4HA9B@91061,COG0263@1,COG0263@2	NA|NA|NA	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NHHNPPIF_02190	322159.STER_1677	5.8e-286	989.6	Bacilli	XK27_00765			ko:K01992		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1TSZA@1239,28MBB@1,2ZAPV@2,4HDKH@91061	NA|NA|NA		
NHHNPPIF_02191	1046629.Ssal_00328	8.1e-134	483.0	Bacilli	ecsA_2			ko:K01990		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1TQIH@1239,4HCEU@91061,COG1131@1,COG1131@2	NA|NA|NA	V	abc transporter atp-binding protein
NHHNPPIF_02192	904306.HMPREF9192_0656	5.2e-125	453.8	Bacilli				ko:K07150					ko00000				Bacteria	1TQWV@1239,4HEYY@91061,COG1811@1,COG1811@2	NA|NA|NA	S	Protein of unknown function (DUF554)
NHHNPPIF_02193	322159.STER_1681	0.0	2311.2	Bacilli	addA		3.6.4.12	ko:K16898					ko00000,ko01000,ko03400				Bacteria	1TQ35@1239,4HA64@91061,COG1074@1,COG1074@2	NA|NA|NA	L	ATP-dependent helicase nuclease subunit A
NHHNPPIF_02194	264199.stu1717	0.0	2120.1	Bacilli	rexB	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.21.3,3.6.4.12	ko:K01153,ko:K16899					ko00000,ko01000,ko02048,ko03400				Bacteria	1TQJW@1239,4HAY6@91061,COG3857@1,COG3857@2	NA|NA|NA	L	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NHHNPPIF_02195	435842.HMPREF0848_01378	2.4e-55	221.5	Bacilli	liaI			ko:K11619	ko02020,map02020	M00754			ko00000,ko00001,ko00002				Bacteria	1VGSF@1239,4IRBC@91061,COG4758@1,COG4758@2	NA|NA|NA	S	membrane
NHHNPPIF_02196	435842.HMPREF0848_01379	2.7e-09	67.0	Bacilli	XK27_02470												Bacteria	1VBF7@1239,4HHGZ@91061,COG3279@1,COG3279@2	NA|NA|NA	K	LytTr DNA-binding domain protein
NHHNPPIF_02197	1046629.Ssal_00311	3e-53	214.5	Bacteria													Bacteria	COG4640@1,COG4640@2	NA|NA|NA	KT	response to antibiotic
NHHNPPIF_02198	1046629.Ssal_00311	1.4e-08	65.5	Bacteria													Bacteria	COG4640@1,COG4640@2	NA|NA|NA	KT	response to antibiotic
NHHNPPIF_02199	1046629.Ssal_00311	9.1e-18	95.1	Bacteria													Bacteria	COG4640@1,COG4640@2	NA|NA|NA	KT	response to antibiotic
NHHNPPIF_02200	435842.HMPREF0848_01381	9.8e-80	303.5	Bacilli	yebC			ko:K16637					ko00000,ko02042				Bacteria	1VK5M@1239,4HS44@91061,COG3064@1,COG3064@2	NA|NA|NA	M	Membrane
NHHNPPIF_02201	1046629.Ssal_00310	1.1e-16	92.0	Bacilli	yebC			ko:K16637					ko00000,ko02042				Bacteria	1VK5M@1239,4HS44@91061,COG3064@1,COG3064@2	NA|NA|NA	M	Membrane
NHHNPPIF_02202	904306.HMPREF9192_0643	1.2e-258	898.7	Bacilli	XK27_03190			ko:K16785	ko02010,map02010	M00582			ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35			Bacteria	1TSZZ@1239,4HB54@91061,COG0561@1,COG0561@2,COG4696@1,COG4696@2	NA|NA|NA	S	hydrolases of the HAD superfamily
NHHNPPIF_02203	264199.stu1724	1.5e-172	612.1	Bacilli	ansA		3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110		R00485	RC00010,RC02798	ko00000,ko00001,ko01000				Bacteria	1TPP9@1239,4H9YJ@91061,COG0252@1,COG0252@2	NA|NA|NA	EJ	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NHHNPPIF_02204	322159.STER_1700	0.0	1315.1	Bacilli	recG	GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494	3.6.4.12	ko:K03655	ko03440,map03440				ko00000,ko00001,ko01000,ko03400				Bacteria	1TQ6I@1239,4HAWN@91061,COG1200@1,COG1200@2	NA|NA|NA	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NHHNPPIF_02205	322159.STER_1701	1.8e-185	655.2	Bacilli	alr		5.1.1.1,5.1.1.5	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502		R00401	RC00285	ko00000,ko00001,ko01000,ko01011				Bacteria	1TNYY@1239,4HA95@91061,COG0787@1,COG0787@2	NA|NA|NA	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NHHNPPIF_02206	322159.STER_1702	3.1e-62	244.2	Bacilli	acpS		2.7.6.3,2.7.8.7,5.1.1.1	ko:K00950,ko:K00997,ko:K01775	ko00473,ko00770,ko00790,ko01100,ko01502,map00473,map00770,map00790,map01100,map01502	M00126,M00841	R00401,R01625,R03503	RC00002,RC00017,RC00285	ko00000,ko00001,ko00002,ko01000,ko01011			iYO844.BSU04620	Bacteria	1VA0T@1239,4HKBI@91061,COG0736@1,COG0736@2	NA|NA|NA	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NHHNPPIF_02207	322159.STER_1703	2.5e-197	694.5	Firmicutes	aroF		2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000			iHN637.CLJU_RS07240	Bacteria	1TQI4@1239,COG0722@1,COG0722@2	NA|NA|NA	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NHHNPPIF_02208	322159.STER_1704	3.8e-198	697.2	Firmicutes	aroF		2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000			iHN637.CLJU_RS07240	Bacteria	1TQI4@1239,COG0722@1,COG0722@2	NA|NA|NA	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NHHNPPIF_02209	264199.stu1730	0.0	1654.8	Bacilli	secA	GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680		ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335			ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4			Bacteria	1TPEY@1239,4HA22@91061,COG0653@1,COG0653@2	NA|NA|NA	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NHHNPPIF_02211	264199.stu1732	6.7e-189	666.4	Bacilli	manA		5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000				Bacteria	1VRGI@1239,4HBFW@91061,COG1482@1,COG1482@2	NA|NA|NA	G	mannose-6-phosphate isomerase
NHHNPPIF_02212	264199.stu1733	9.1e-172	609.4	Bacilli	scrK		2.7.1.2,2.7.1.4	ko:K00845,ko:K00847	ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R00760,R00867,R01600,R01786,R03920	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000				Bacteria	1TQU4@1239,4HA1C@91061,COG1940@1,COG1940@2	NA|NA|NA	GK	Fructokinase
NHHNPPIF_02213	322159.STER_1710	0.0	1200.7	Bacilli	scrA		2.7.1.211	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	M00269	R00811	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9			Bacteria	1TP5X@1239,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2	NA|NA|NA	G	pts system
NHHNPPIF_02214	322159.STER_1711	2.3e-289	1000.7	Bacilli	scrB		3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100		R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000		GH32		Bacteria	1TPAE@1239,4H9Y7@91061,COG1621@1,COG1621@2	NA|NA|NA	G	invertase
NHHNPPIF_02215	322159.STER_1712	9.2e-178	629.4	Bacilli	scrR			ko:K02529,ko:K03484					ko00000,ko03000				Bacteria	1TQ7K@1239,4H9V1@91061,COG1609@1,COG1609@2	NA|NA|NA	K	Transcriptional
NHHNPPIF_02216	264199.stu1738	3.6e-73	280.8	Bacilli	nusB			ko:K03625					ko00000,ko03009,ko03021				Bacteria	1VA9B@1239,4HKMU@91061,COG0781@1,COG0781@2	NA|NA|NA	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NHHNPPIF_02217	322159.STER_1714	3.4e-62	244.2	Bacilli	yqhY			ko:K10947					ko00000,ko03000				Bacteria	1V4IC@1239,4HJ7T@91061,COG1302@1,COG1302@2	NA|NA|NA	S	protein conserved in bacteria
NHHNPPIF_02218	264199.stu1740	9.3e-98	362.8	Bacilli	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576		ko:K02356					ko00000,ko03012				Bacteria	1TR8P@1239,4H9YX@91061,COG0231@1,COG0231@2	NA|NA|NA	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NHHNPPIF_02219	264199.stu1741	1.1e-83	315.8	Bacilli	comEB		3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044				Bacteria	1V8V0@1239,4IQZA@91061,COG2131@1,COG2131@2	NA|NA|NA	F	ComE operon protein 2
NHHNPPIF_02220	264199.stu1742	7.2e-192	676.4	Bacilli	pepP	GO:0003674,GO:0003824,GO:0004177,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271,ko:K08326					ko00000,ko01000,ko01002				Bacteria	1TQ44@1239,4HAT7@91061,COG0006@1,COG0006@2	NA|NA|NA	E	Belongs to the peptidase M24B family
NHHNPPIF_02223	904306.HMPREF9192_0620	7.7e-11	72.4	Firmicutes				ko:K01990		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1TPBQ@1239,COG1131@1,COG1131@2	NA|NA|NA	V	'abc transporter, ATP-binding protein
NHHNPPIF_02224	435842.HMPREF0848_01406	1.3e-58	232.3	Firmicutes				ko:K01990		M00254			ko00000,ko00002,ko02000	3.A.1			Bacteria	1TPBQ@1239,COG1131@1,COG1131@2	NA|NA|NA	V	'abc transporter, ATP-binding protein
NHHNPPIF_02230	322159.STER_1722	0.0	1866.3	Bacilli	uvrA			ko:K03701	ko03420,map03420				ko00000,ko00001,ko03400				Bacteria	1TPIJ@1239,4HAW9@91061,COG0178@1,COG0178@2	NA|NA|NA	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NHHNPPIF_02231	264199.stu1749	5e-168	597.0	Bacilli	corA			ko:K03284					ko00000,ko02000	1.A.35.1,1.A.35.3			Bacteria	1TPI8@1239,4HE7S@91061,COG0598@1,COG0598@2	NA|NA|NA	P	COG0598 Mg2 and Co2 transporters
NHHNPPIF_02232	322159.STER_1724	2e-123	448.4	Bacilli	XK27_01040												Bacteria	1VF5N@1239,4HJMB@91061,COG4858@1,COG4858@2	NA|NA|NA	S	Pfam PF06570
NHHNPPIF_02234	264199.stu1752	9.7e-36	155.6	Bacilli	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904		ko:K02963,ko:K03111,ko:K15125	ko03010,ko03030,ko03430,ko03440,ko05133,map03010,map03030,map03430,map03440,map05133	M00178			br01610,ko00000,ko00001,ko00002,ko00536,ko03011,ko03029,ko03032,ko03400				Bacteria	1V9XS@1239,4HKCC@91061,COG0238@1,COG0238@2	NA|NA|NA	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NHHNPPIF_02235	264199.stu1753	2.7e-91	341.3	Bacilli	ssb			ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440				ko00000,ko00001,ko03029,ko03032,ko03400				Bacteria	1V3WT@1239,4HH8I@91061,COG0629@1,COG0629@2	NA|NA|NA	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NHHNPPIF_02236	264199.stu1754	3.9e-47	193.7	Bacilli	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904		ko:K02990	ko03010,map03010	M00178			br01610,ko00000,ko00001,ko00002,ko03011,ko03029				Bacteria	1VA18@1239,4HKHD@91061,COG0360@1,COG0360@2	NA|NA|NA	J	Binds together with S18 to 16S ribosomal RNA
NHHNPPIF_02237	996306.SSUR61_1077	2.1e-41	176.4	Streptococcus suis	XK27_05745												Bacteria	1U8WY@1239,1WSBS@1307,2BJFN@1,32DS8@2,4IIVI@91061	NA|NA|NA		
NHHNPPIF_02239	264199.stu1757	3.6e-229	800.4	Bacilli	mutY			ko:K03575	ko03410,map03410				ko00000,ko00001,ko01000,ko03400				Bacteria	1TPUT@1239,4H9UM@91061,COG1194@1,COG1194@2	NA|NA|NA	L	A G-specific adenine glycosylase
NHHNPPIF_02243	322159.STER_1736	0.0	1711.8	Bacilli	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440		R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400				Bacteria	1TPKJ@1239,4H9S7@91061,COG0258@1,COG0258@2,COG0749@1,COG0749@2	NA|NA|NA	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NHHNPPIF_02244	322159.STER_1737	0.0	1454.5	Bacilli	mutS2	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391		ko:K07456	ko03430,map03430				ko00000,ko00001,ko03400				Bacteria	1TP5W@1239,4H9NZ@91061,COG1193@1,COG1193@2	NA|NA|NA	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NHHNPPIF_02245	322159.STER_1738	6.7e-93	346.7	Bacteria	cvpA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944		ko:K03558					ko00000				Bacteria	COG1286@1,COG1286@2	NA|NA|NA	S	toxin biosynthetic process
NHHNPPIF_02246	1302863.I872_01550	2.3e-13	81.3	Bacilli	zapA	GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000921,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032185,GO:0032505,GO:0032506,GO:0034622,GO:0042802,GO:0043093,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051301,GO:0061640,GO:0065003,GO:0070925,GO:0071840,GO:0090529,GO:1902410,GO:1903047		ko:K09888					ko00000,ko03036				Bacteria	1VFZS@1239,4HP4T@91061,COG3027@1,COG3027@2	NA|NA|NA	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NHHNPPIF_02247	862969.SCI_0200	4e-163	581.3	Streptococcus anginosus group													Bacteria	1V8H0@1239,2AQ9M@1,31FFI@2,42EJB@671232,4ISNC@91061	NA|NA|NA	S	Uncharacterised protein family (UPF0236)
NHHNPPIF_02248	888049.HMPREF8578_0789	2.9e-07	60.8	Streptococcus oralis													Bacteria	1TX3Q@1239,1WQ84@1303,2DJ5I@1,304SI@2,4I5ZW@91061	NA|NA|NA		
NHHNPPIF_02249	1069533.Sinf_1782	3.6e-111	407.9	Bacilli				ko:K03496					ko00000,ko03036,ko04812				Bacteria	1V6Q6@1239,4HINH@91061,COG1192@1,COG1192@2	NA|NA|NA	D	CobQ CobB MinD ParA nucleotide binding domain protein
NHHNPPIF_02250	1035184.HMPREF1042_2326	3.5e-71	274.6	Streptococcus anginosus group	tnpR												Bacteria	1UZM8@1239,42EG7@671232,4IQ67@91061,COG1961@1,COG1961@2	NA|NA|NA	L	Resolvase, N terminal domain
NHHNPPIF_02251	862969.SCI_0195	8.4e-184	649.8	Streptococcus anginosus group													Bacteria	1V2SB@1239,42E61@671232,4HFEX@91061,COG3843@1,COG3843@2	NA|NA|NA	U	Relaxase/Mobilisation nuclease domain
NHHNPPIF_02252	873447.SPB_0385	8.5e-275	952.6	Bacilli	topB		5.99.1.2	ko:K03169					ko00000,ko01000,ko03032				Bacteria	1TPJD@1239,4HAZV@91061,COG0550@1,COG0550@2	NA|NA|NA	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NHHNPPIF_02253	873447.SPB_0386	0.0	1209.5	Bacilli													Bacteria	1TQN4@1239,4HN8F@91061,COG0358@1,COG0358@2,COG4227@1,COG4227@2	NA|NA|NA	L	Psort location Cytoplasmic, score
NHHNPPIF_02255	1035184.HMPREF1042_2332	1.4e-44	185.7	Streptococcus anginosus group													Bacteria	1TTW0@1239,29Y89@1,30K1Z@2,42EHW@671232,4I3RM@91061	NA|NA|NA	S	Bacterial mobilisation protein (MobC)
# 2016 queries scanned
# Total time (seconds): 4.90557098389
# Rate: 410.96 q/s