GCA_005864055.1 - 2 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

VBSR01000019.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 19.1	lanthipeptide-class-iii,RRE-containing	1	30,967

VBSR01000093.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 93.1	NRPS-like	1	5,512

Region	Type	From	To	Most similar known cluster	Similarity
Region 19.1	lanthipeptide-class-iii,RRE-containing	1	30,967
Region 93.1	NRPS-like	1	5,512

No secondary metabolite regions were found in these records:: VBSR01000001.1; VBSR01000002.1; VBSR01000003.1; VBSR01000004.1; VBSR01000005.1; VBSR01000006.1; VBSR01000007.1; VBSR01000008.1; VBSR01000009.1; VBSR01000010.1; VBSR01000011.1; VBSR01000012.1; VBSR01000013.1; VBSR01000014.1; VBSR01000015.1; VBSR01000016.1; VBSR01000017.1; VBSR01000018.1; VBSR01000020.1; VBSR01000021.1; VBSR01000022.1; VBSR01000023.1; VBSR01000024.1; VBSR01000025.1; VBSR01000026.1; VBSR01000027.1; VBSR01000028.1; VBSR01000029.1; VBSR01000030.1; VBSR01000031.1; VBSR01000032.1; VBSR01000033.1; VBSR01000034.1; VBSR01000035.1; VBSR01000036.1; VBSR01000037.1; VBSR01000038.1; VBSR01000039.1; VBSR01000040.1; VBSR01000041.1; VBSR01000042.1; VBSR01000043.1; VBSR01000044.1; VBSR01000045.1; VBSR01000046.1; VBSR01000047.1; VBSR01000048.1; VBSR01000049.1; VBSR01000050.1; VBSR01000051.1; VBSR01000052.1; VBSR01000053.1; VBSR01000054.1; VBSR01000055.1; VBSR01000056.1; VBSR01000057.1; VBSR01000058.1; VBSR01000059.1; VBSR01000060.1; VBSR01000061.1; VBSR01000062.1; VBSR01000063.1; VBSR01000064.1; VBSR01000065.1; VBSR01000066.1; VBSR01000067.1; VBSR01000068.1; VBSR01000069.1; VBSR01000070.1; VBSR01000071.1; VBSR01000072.1; VBSR01000073.1; VBSR01000074.1; VBSR01000075.1; VBSR01000076.1; VBSR01000077.1; VBSR01000078.1; VBSR01000079.1; VBSR01000080.1; VBSR01000081.1; VBSR01000082.1; VBSR01000083.1; VBSR01000084.1; VBSR01000085.1; VBSR01000086.1; VBSR01000087.1; VBSR01000088.1; VBSR01000089.1; VBSR01000090.1; VBSR01000091.1; VBSR01000092.1; VBSR01000094.1; VBSR01000095.1; VBSR01000096.1; VBSR01000097.1; VBSR01000098.1; VBSR01000099.1; VBSR01000100.1; VBSR01000101.1; VBSR01000102.1; VBSR01000103.1; VBSR01000104.1; VBSR01000105.1; VBSR01000106.1; VBSR01000107.1; VBSR01000108.1; VBSR01000109.1; VBSR01000110.1; VBSR01000111.1; VBSR01000112.1; VBSR01000113.1; VBSR01000114.1; VBSR01000115.1; VBSR01000116.1; VBSR01000117.1; VBSR01000118.1; VBSR01000119.1; VBSR01000120.1; VBSR01000121.1; VBSR01000122.1; VBSR01000123.1; VBSR01000124.1; VBSR01000125.1; VBSR01000126.1; VBSR01000127.1; VBSR01000128.1; VBSR01000129.1; VBSR01000130.1; VBSR01000131.1; VBSR01000132.1; VBSR01000133.1; VBSR01000134.1; VBSR01000135.1; VBSR01000136.1; VBSR01000137.1; VBSR01000138.1; VBSR01000139.1; VBSR01000140.1; VBSR01000141.1; VBSR01000142.1; VBSR01000143.1; VBSR01000144.1; VBSR01000145.1; VBSR01000146.1; VBSR01000147.1; VBSR01000148.1; VBSR01000149.1; VBSR01000150.1; VBSR01000151.1

Compact view

VBSR01000019.1 - Region 1 - RRE-containing,lanthipeptide-class-iii

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Location: 1 - 30,967 nt. (total: 30,967 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-iii: (micKC and not PKS_KS)
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Lanthipeptides

KnownClusterBlast

Lanthipeptide predictions

Lanthipeptide(s) for ctg19_6 - Putative Class III

ctg19_9 leader / core peptide: MQVLDLQQLGNAGGAGLE - DDhaKDhaFDhaLICIGDhaRVGDGNHDhaDhaHKKHHKGKKH

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Similar known gene clusters

No matches found.

Lanthipeptides

Core peptide predictions

ctg19_9 - Class III

Cleavage pHMM score: -2.40

RODEO score: 0

Monoisotopic mass: 3302.7 Da

Molecular weight: 3304.7 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 3322.7 Da N = 1; 3340.7 Da N = 2; 3358.7 Da N = 3; 3376.8 Da N = 4; 3394.8 Da N = 5

VBSR01000093.1 - Region 1 - NRPS-like

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Location: 1 - 5,512 nt. (total: 5,512 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 5512:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg93_2

Search NORINE for peptide: strict or relaxed

AMP-binding (194..561): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVtaLAvVYK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 70% (weak)