# emapper version: emapper-2.0.1b-2-g816e190 emapper DB: 2.0 # command: ./emapper.py -i Lactobacillus_fermentum/1.contigAnn/FFN/A00000063.ffn --translate --temp_dir Lactobacillus_fermentum/4.eggNOG_mapper --output_dir Lactobacillus_fermentum/4.eggNOG_mapper --output A00000063 --cpu 36 --keep_mapping_files -m diamond # time: Tue Jun 14 13:40:35 2022 #query_name seed_eggNOG_ortholog seed_ortholog_evalue seed_ortholog_score best_tax_level Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction taxonomic scope eggNOG OGs best eggNOG OG COG Functional cat. eggNOG free text desc. KIAJIJGH_00001 334390.LAF_0736 6e-185 653.3 Lactobacillaceae ribF 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS06310 Bacteria 1TPKS@1239,3F3TG@33958,4H9KE@91061,COG0196@1,COG0196@2 NA|NA|NA H Belongs to the ribF family KIAJIJGH_00002 334390.LAF_0735 6.8e-167 593.2 Lactobacillaceae truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177,ko:K03483 ko00000,ko01000,ko03000,ko03016 iSB619.SA_RS06305 Bacteria 1TP9Y@1239,3F3NX@33958,4HA9X@91061,COG0130@1,COG0130@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs KIAJIJGH_00003 334390.LAF_0734 4.2e-59 233.8 Lactobacillaceae rbfA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 ko:K02834 ko00000,ko03009 Bacteria 1VA0P@1239,3F6WZ@33958,4HII1@91061,COG0858@1,COG0858@2 NA|NA|NA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA KIAJIJGH_00004 334390.LAF_0733 0.0 1277.3 Lactobacillaceae infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K02519 ko00000,ko03012,ko03029 Bacteria 1TPAI@1239,3F3JV@33958,4HA8S@91061,COG0532@1,COG0532@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex KIAJIJGH_00005 334390.LAF_0732 3.2e-50 204.1 Lactobacillaceae ylxQ ko:K07590,ko:K07742 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEYG@1239,3F7ZK@33958,4HNY7@91061,COG1358@1,COG1358@2 NA|NA|NA J ribosomal protein KIAJIJGH_00006 334390.LAF_0731 1.4e-47 195.3 Lactobacillaceae ylxR ko:K02600,ko:K07742 ko00000,ko03009,ko03021 Bacteria 1VEJS@1239,3F7E2@33958,4HKBY@91061,COG2740@1,COG2740@2 NA|NA|NA K Protein of unknown function (DUF448) KIAJIJGH_00007 334390.LAF_0730 3.7e-224 783.9 Lactobacillaceae nusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K02600,ko:K02945 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03009,ko03011,ko03021 Bacteria 1TPB3@1239,3F3KZ@33958,4HA7F@91061,COG0195@1,COG0195@2 NA|NA|NA K Participates in both transcription termination and antitermination KIAJIJGH_00008 334390.LAF_0729 3.3e-83 314.3 Lactobacillaceae rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 ko:K09748 ko00000,ko03009 Bacteria 1V6KT@1239,3F6GZ@33958,4HH88@91061,COG0779@1,COG0779@2 NA|NA|NA J Required for maturation of 30S ribosomal subunits KIAJIJGH_00009 334390.LAF_0728 0.0 1990.7 Lactobacillaceae carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPID@1239,3F3MD@33958,4HAEY@91061,COG0458@1,COG0458@2 NA|NA|NA F Carbamoyl-phosphate synthase KIAJIJGH_00010 334390.LAF_0727 2.8e-207 727.6 Lactobacillaceae carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955,ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1383,iYO844.BSU15510 Bacteria 1TQ8N@1239,3F43R@33958,4H9Z0@91061,COG0505@1,COG0505@2 NA|NA|NA F Carbamoyl-phosphate synthetase glutamine chain KIAJIJGH_00011 334390.LAF_0726 1.2e-196 692.2 Lactobacillaceae argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1782,iSSON_1240.SSON_4131,iYO844.BSU11190 Bacteria 1TPVI@1239,3F5DZ@33958,4H9YD@91061,COG0002@1,COG0002@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde KIAJIJGH_00012 334390.LAF_0725 4e-207 727.2 Lactobacillaceae argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35,2.7.2.8 ko:K00620,ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282,R02649 RC00002,RC00004,RC00043,RC00064 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1783 Bacteria 1TPBP@1239,3F433@33958,4H9TQ@91061,COG1364@1,COG1364@2 NA|NA|NA E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate KIAJIJGH_00013 334390.LAF_0724 2.7e-137 494.6 Lactobacillaceae argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP0N@1239,3F5QN@33958,4HH91@91061,COG0548@1,COG0548@2 NA|NA|NA F Belongs to the acetylglutamate kinase family. ArgB subfamily KIAJIJGH_00014 334390.LAF_0723 8.3e-218 762.7 Lactobacillaceae argD GO:0003674,GO:0003824,GO:0003992,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP9S@1239,3F52J@33958,4H9VZ@91061,COG4992@1,COG4992@2 NA|NA|NA E acetylornithine KIAJIJGH_00015 334390.LAF_0722 0.0 2840.4 Lactobacillaceae polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K02342,ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TPAG@1239,3F4AN@33958,4H9RF@91061,COG2176@1,COG2176@2 NA|NA|NA L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity KIAJIJGH_00016 334390.LAF_0721 0.0 1127.5 Lactobacillaceae proS GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iJN678.proS,iUTI89_1310.UTI89_C0210 Bacteria 1TRBV@1239,3F44A@33958,4H9NN@91061,COG0442@1,COG0442@2 NA|NA|NA J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS KIAJIJGH_00017 334390.LAF_0720 1.8e-229 801.6 Lactobacillaceae rseP GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0040007,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 3.4.21.107,3.4.21.116 ko:K04771,ko:K06399,ko:K11749,ko:K16922 ko01503,ko02020,ko02024,ko04112,map01503,map02020,map02024,map04112 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1TPMC@1239,3F3TM@33958,4HAQ5@91061,COG0750@1,COG0750@2 NA|NA|NA M zinc metalloprotease KIAJIJGH_00018 334390.LAF_0719 1.1e-133 482.6 Lactobacillaceae cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1397 Bacteria 1UPNB@1239,3F4AF@33958,4IV81@91061,COG0575@1,COG0575@2 NA|NA|NA I Belongs to the CDS family KIAJIJGH_00019 334390.LAF_0718 1.7e-142 511.9 Lactobacillaceae uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 Bacteria 1TQTS@1239,3F42M@33958,4HA37@91061,COG0020@1,COG0020@2 NA|NA|NA H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids KIAJIJGH_00020 334390.LAF_0717 1.4e-93 349.0 Lactobacillaceae frr GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02838 ko00000,ko03012 Bacteria 1V1F2@1239,3F4X2@33958,4HFSH@91061,COG0233@1,COG0233@2 NA|NA|NA J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another KIAJIJGH_00021 334390.LAF_0716 7e-130 469.9 Lactobacillaceae pyrH GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 R00158 RC00002 ko00000,ko00001,ko01000 iSB619.SA_RS06240 Bacteria 1TPXN@1239,3F42J@33958,4H9UB@91061,COG0528@1,COG0528@2 NA|NA|NA F Catalyzes the reversible phosphorylation of UMP to UDP KIAJIJGH_00022 334390.LAF_0715 3.2e-153 547.7 Lactobacillaceae tsf GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 ko:K02357 ko00000,ko03012,ko03029 Bacteria 1TPFJ@1239,3F459@33958,4HBDV@91061,COG0264@1,COG0264@2 NA|NA|NA J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome KIAJIJGH_00023 334390.LAF_0714 1.6e-140 505.4 Lactobacillaceae rpsB GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02967 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPNA@1239,3F3M1@33958,4H9N5@91061,COG0052@1,COG0052@2 NA|NA|NA J Belongs to the universal ribosomal protein uS2 family KIAJIJGH_00024 334390.LAF_0713 8.7e-47 192.6 Lactobacillaceae yazA ko:K07461 ko00000 Bacteria 1VEZF@1239,3F7G2@33958,4HNHJ@91061,COG2827@1,COG2827@2 NA|NA|NA L GIY-YIG catalytic domain protein KIAJIJGH_00025 334390.LAF_0712 8e-137 493.0 Lactobacillaceae yabB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.223 ko:K07461,ko:K15460 ko00000,ko01000,ko03016 Bacteria 1TQ25@1239,3F4C5@33958,4HA8W@91061,COG4123@1,COG4123@2 NA|NA|NA L Methyltransferase small domain KIAJIJGH_00026 334390.LAF_0711 3.3e-115 421.0 Lactobacillaceae plsC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008374,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0042171,GO:0044464,GO:0071617,GO:0071944 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1U8N2@1239,3F4QB@33958,4HDQR@91061,COG0204@1,COG0204@2 NA|NA|NA I Acyltransferase KIAJIJGH_00027 1203076.CAKF01000010_gene212 2.7e-27 127.5 Lactobacillaceae yneF ko:K09976 ko00000 Bacteria 1VEJC@1239,3F809@33958,4HKMJ@91061,COG3763@1,COG3763@2 NA|NA|NA S Uncharacterised protein family (UPF0154) KIAJIJGH_00028 334390.LAF_0709 9.2e-37 159.1 Lactobacillaceae ynzC Bacteria 1VEKJ@1239,3F87S@33958,4HNIB@91061,COG4224@1,COG4224@2 NA|NA|NA S UPF0291 protein KIAJIJGH_00029 334390.LAF_0708 4.2e-115 420.6 Lactobacillaceae lexA 3.4.21.88 ko:K01356 M00729 ko00000,ko00002,ko01000,ko01002,ko03400 Bacteria 1TQ3H@1239,3F3JG@33958,4HBHA@91061,COG1974@1,COG1974@2 NA|NA|NA K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair KIAJIJGH_00030 334390.LAF_0707 3.3e-214 750.7 Lactobacillaceae mvaS 2.3.3.10 ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 M00088,M00095 R01978 RC00004,RC00503 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR4K@1239,3F425@33958,4HA67@91061,COG3425@1,COG3425@2 NA|NA|NA I Hydroxymethylglutaryl-CoA synthase KIAJIJGH_00031 908339.HMPREF9265_0021 2.8e-121 441.4 Lactobacillaceae lutA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K18928 ko00000 iEC042_1314.EC042_0340,iEcSMS35_1347.EcSMS35_0338 Bacteria 1TPFC@1239,3F4GX@33958,4HAKC@91061,COG0247@1,COG0247@2 NA|NA|NA C Cysteine-rich domain KIAJIJGH_00032 944562.HMPREF9102_0625 1.1e-244 852.4 Lactobacillaceae lutB ko:K18929 ko00000 iSF_1195.SF0259,iSFxv_1172.SFxv_0274,iS_1188.S0280 Bacteria 1TREQ@1239,3F4IV@33958,4H9UI@91061,COG1139@1,COG1139@2 NA|NA|NA C 4Fe-4S dicluster domain KIAJIJGH_00033 944562.HMPREF9102_0624 5.7e-87 327.4 Lactobacillaceae yrjD ko:K00782 ko00000 Bacteria 1UZAK@1239,3F4UV@33958,4HH3R@91061,COG1556@1,COG1556@2 NA|NA|NA S LUD domain KIAJIJGH_00035 1400520.LFAB_17410 2.5e-44 186.4 Lactobacillaceae Bacteria 1VXP5@1239,3F5AT@33958,4HWZF@91061,COG3203@1,COG3203@2,COG4932@1,COG4932@2 NA|NA|NA M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane KIAJIJGH_00036 908339.HMPREF9265_1226 3.1e-08 64.7 Bacilli ko:K20276 ko02024,map02024 ko00000,ko00001 Bacteria 1UMBY@1239,4ITUG@91061,COG2373@1,COG2373@2 NA|NA|NA Q Signal peptide protein, YSIRK family KIAJIJGH_00037 557436.Lreu_1197 7.7e-25 119.8 Lactobacillaceae ko:K02612 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 1V9YV@1239,3F7D5@33958,4HKC6@91061,COG2151@1,COG2151@2 NA|NA|NA S Iron-sulfur cluster assembly protein KIAJIJGH_00038 349123.Lreu23DRAFT_5177 3e-36 157.5 Lactobacillaceae sdaAA 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 Bacteria 1TP79@1239,3F3X8@33958,4HAI1@91061,COG1760@1,COG1760@2 NA|NA|NA E L-serine dehydratase, iron-sulfur-dependent, alpha subunit KIAJIJGH_00039 334390.LAF_0033 5.3e-184 650.2 Lactobacillaceae clpL ko:K04086 ko00000,ko03110 Bacteria 1TPMU@1239,3F43D@33958,4HA0V@91061,COG0542@1,COG0542@2 NA|NA|NA O associated with various cellular activities KIAJIJGH_00040 334390.LAF_0033 1.3e-45 188.7 Lactobacillaceae clpL ko:K04086 ko00000,ko03110 Bacteria 1TPMU@1239,3F43D@33958,4HA0V@91061,COG0542@1,COG0542@2 NA|NA|NA O associated with various cellular activities KIAJIJGH_00041 334390.LAF_0033 1.3e-35 155.2 Lactobacillaceae clpL ko:K04086 ko00000,ko03110 Bacteria 1TPMU@1239,3F43D@33958,4HA0V@91061,COG0542@1,COG0542@2 NA|NA|NA O associated with various cellular activities KIAJIJGH_00042 334390.LAF_0032 1e-34 152.1 Lactobacillaceae Bacteria 1VZ0G@1239,2BZQ9@1,3490W@2,3F7PN@33958,4HY72@91061 NA|NA|NA KIAJIJGH_00043 334390.LAF_0031 8.5e-218 762.7 Lactobacillaceae patA 2.6.1.1 ko:K00812,ko:K00841,ko:K10907 ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00525 R00355,R00694,R00734,R00896,R02433,R02619,R04467,R05052 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP0J@1239,3F3MX@33958,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase KIAJIJGH_00044 334390.LAF_0030 4.1e-181 640.6 Lactobacillaceae ldhD 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 R00704 RC00044 ko00000,ko00001,ko01000 Bacteria 1TSZ6@1239,3F4US@33958,4HCIS@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family KIAJIJGH_00045 334390.LAF_0029 3.2e-183 647.5 Lactobacillaceae ko:K06889 ko00000 Bacteria 1TQYU@1239,3F43H@33958,4HC4H@91061,COG1073@1,COG1073@2 NA|NA|NA D Alpha beta KIAJIJGH_00046 334390.LAF_0028 1.7e-81 308.5 Lactobacillaceae pacA 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 Bacteria 1TPZS@1239,3F4NH@33958,4HC4Y@91061,COG3049@1,COG3049@2 NA|NA|NA M Linear amide C-N hydrolase, choloylglycine hydrolase family protein KIAJIJGH_00047 334390.LAF_0027 7.4e-110 403.3 Bacteria ysdA ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria COG1668@1,COG1668@2 NA|NA|NA CP transmembrane transport KIAJIJGH_00048 334390.LAF_1375 1.2e-42 178.7 Lactobacillaceae nrdG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0031250,GO:0032991,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 1.97.1.4 ko:K04068 R04710 ko00000,ko01000 iE2348C_1286.E2348C_4563 Bacteria 1V1HG@1239,3F46H@33958,4HGJ9@91061,COG0602@1,COG0602@2 NA|NA|NA O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine KIAJIJGH_00049 334390.LAF_1374 1.2e-157 562.4 Lactobacillaceae sufD ko:K07033,ko:K09015 ko00000 Bacteria 1U5WR@1239,3F6MK@33958,4IFK7@91061,COG0719@1,COG0719@2 NA|NA|NA O Uncharacterized protein family (UPF0051) KIAJIJGH_00050 334390.LAF_1373 4.6e-236 823.5 Lactobacillaceae ko:K02824,ko:K03458,ko:K16169 ko00000,ko02000 2.A.40,2.A.40.1.1,2.A.40.1.2,2.A.40.3.1 Bacteria 1TNZZ@1239,3FC8X@33958,4HCX6@91061,COG2233@1,COG2233@2 NA|NA|NA F Permease KIAJIJGH_00051 1400520.LFAB_14405 1.3e-294 1018.5 Lactobacillaceae cadA Bacteria 1TQ07@1239,3F4JI@33958,4H9SP@91061,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase KIAJIJGH_00052 1138822.PL11_10630 1.2e-21 108.2 Lactobacillaceae ko:K04763 ko00000,ko03036 Bacteria 1V2RX@1239,3F4SP@33958,4IEJ7@91061,COG0582@1,COG0582@2 NA|NA|NA L Integrase KIAJIJGH_00053 334390.LAF_0615 5.6e-36 156.4 Lactobacillaceae gshF 6.3.2.2 ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 M00118,M00582 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TPGX@1239,3F506@33958,4HAMJ@91061,COG2918@1,COG2918@2 NA|NA|NA H Belongs to the glutamate--cysteine ligase type 1 family KIAJIJGH_00054 334390.LAF_0616 0.0 1163.7 Lactobacillaceae rnjB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1TQ9G@1239,3F3U9@33958,4HAAP@91061,COG0595@1,COG0595@2 NA|NA|NA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay KIAJIJGH_00055 334390.LAF_0617 1.1e-164 585.9 Lactobacillaceae Bacteria 1VXFK@1239,3FBB5@33958,4HX6X@91061,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat KIAJIJGH_00056 334390.LAF_0618 9.5e-225 785.8 Lactobacillaceae tuf GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009274,GO:0009275,GO:0009986,GO:0010339,GO:0016020,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035821,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 ko:K02358,ko:K15771 ko02010,map02010 M00491 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 3.A.1.1.16,3.A.1.1.2 Bacteria 1TPKC@1239,3F3ZP@33958,4HAEH@91061,COG0050@1,COG0050@2 NA|NA|NA J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis KIAJIJGH_00057 334390.LAF_0619 5.7e-215 753.4 Lactobacillaceae tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 ko:K03545 ko00000 Bacteria 1TQQ8@1239,3F40B@33958,4H9Q8@91061,COG0544@1,COG0544@2 NA|NA|NA D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase KIAJIJGH_00058 334390.LAF_0620 1.5e-233 815.1 Lactobacillaceae clpX GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 Bacteria 1TQ00@1239,3F41K@33958,4H9U4@91061,COG1219@1,COG1219@2 NA|NA|NA O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP KIAJIJGH_00059 334390.LAF_0621 2.3e-107 394.8 Lactobacillaceae engB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03978 ko00000,ko03036 Bacteria 1TSPW@1239,3F44G@33958,4HBXZ@91061,COG0218@1,COG0218@2 NA|NA|NA D Necessary for normal cell division and for the maintenance of normal septation KIAJIJGH_00060 334390.LAF_0622 8.3e-53 212.6 Lactobacillaceae MA20_27270 Bacteria 1VIQA@1239,3F6WJ@33958,4HM6C@91061,COG1694@1,COG1694@2 NA|NA|NA S mazG nucleotide pyrophosphohydrolase KIAJIJGH_00062 334390.LAF_0624 3.7e-134 484.2 Lactobacillaceae glnQ 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1TNYD@1239,3F3QQ@33958,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein KIAJIJGH_00063 334390.LAF_0625 0.0 1203.7 Lactobacillaceae uvrC ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TP4B@1239,3F3MY@33958,4H9QH@91061,COG0322@1,COG0322@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision KIAJIJGH_00064 334390.LAF_0626 8.7e-248 862.4 Lactobacillaceae obg GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043021,GO:0043022,GO:0043167,GO:0043168,GO:0043934,GO:0044424,GO:0044464,GO:0044877,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03979 ko00000,ko01000,ko03009 Bacteria 1TPX7@1239,3F4ZA@33958,4H9P8@91061,COG0536@1,COG0536@2 NA|NA|NA S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control KIAJIJGH_00065 334390.LAF_0627 4.1e-175 620.5 Lactobacillaceae rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016891,GO:0016893,GO:0016896,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Bacteria 1TRGP@1239,3F4F1@33958,4HABM@91061,COG1234@1,COG1234@2 NA|NA|NA J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA KIAJIJGH_00066 334390.LAF_0628 4.3e-155 553.9 Lactobacillaceae XK27_05435 1.1.1.100 ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1UG37@1239,3FC9N@33958,4HC7Y@91061,COG0300@1,COG0300@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family KIAJIJGH_00067 334390.LAF_0629 0.0 1482.2 Lactobacillaceae recJ ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPXE@1239,3F42C@33958,4H9UP@91061,COG0608@1,COG0608@2 NA|NA|NA L Single-stranded-DNA-specific exonuclease RecJ KIAJIJGH_00068 334390.LAF_0630 2.4e-95 354.8 Lactobacillaceae apt GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.22,2.4.2.7 ko:K00759,ko:K03816,ko:K09685 ko00230,ko01100,ko01110,map00230,map01100,map01110 R00190,R01229,R02142,R04378 RC00063,RC00122 ko00000,ko00001,ko01000,ko03000,ko04147 Bacteria 1V1BV@1239,3F4DB@33958,4HFUA@91061,COG0503@1,COG0503@2 NA|NA|NA F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis KIAJIJGH_00069 334390.LAF_0631 3.6e-61 240.7 Firmicutes Bacteria 1VCR0@1239,2DMJ0@1,32RWW@2 NA|NA|NA S Domain of unknown function (DUF4440) KIAJIJGH_00070 334390.LAF_0632 8.6e-187 659.4 Lactobacillaceae ldhA 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 R00704 RC00044 ko00000,ko00001,ko01000 Bacteria 1TSZ6@1239,3FB6C@33958,4HH0S@91061,COG1052@1,COG1052@2 NA|NA|NA C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family KIAJIJGH_00071 334390.LAF_0633 1.1e-152 545.8 Lactobacillaceae tesE ko:K02509 ko00350,ko01120,map00350,map01120 R04132,R06897 RC01615,RC02595 ko00000,ko00001,ko01000 Bacteria 1TQVG@1239,3F515@33958,4HBMC@91061,COG3971@1,COG3971@2 NA|NA|NA Q hydratase KIAJIJGH_00072 699248.SRA_09381 3.4e-260 904.0 Bacilli ilvD GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP1R@1239,4H9ZG@91061,COG0129@1,COG0129@2 NA|NA|NA E Belongs to the IlvD Edd family KIAJIJGH_00073 797515.HMPREF9103_01631 1e-27 129.4 Lactobacillaceae XK27_02560 ko:K02612 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 1VX9Z@1239,3F7Q5@33958,4HXCM@91061,COG2151@1,COG2151@2 NA|NA|NA S Pfam:DUF59 KIAJIJGH_00074 1046629.Ssal_00845 4.4e-127 461.1 Bacilli yocS ko:K03453 ko00000 2.A.28 Bacteria 1TP85@1239,4HBG6@91061,COG0385@1,COG0385@2 NA|NA|NA S Transporter KIAJIJGH_00075 334390.LAF_0966 3.8e-238 830.5 Lactobacillaceae ydjE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K08369 ko00000,ko02000 2.A.1 Bacteria 1UJIA@1239,3F4Z2@33958,4ITA7@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily KIAJIJGH_00076 334390.LAF_0965 1.1e-195 689.1 Lactobacillaceae leuB GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1TPEM@1239,3F4AY@33958,4HATP@91061,COG0473@1,COG0473@2 NA|NA|NA CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate KIAJIJGH_00077 334390.LAF_0964 9.3e-280 968.8 Lactobacillaceae leuC GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 iEcE24377_1341.EcE24377A_0075,iPC815.YPO0531,iSB619.SA_RS10700 Bacteria 1TPE5@1239,3F4KF@33958,4HAWA@91061,COG0065@1,COG0065@2 NA|NA|NA E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate KIAJIJGH_00078 334390.LAF_0963 3.3e-106 391.0 Lactobacillaceae leuD 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1V1I6@1239,3F47W@33958,4HFTY@91061,COG0066@1,COG0066@2 NA|NA|NA E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate KIAJIJGH_00079 334390.LAF_0962 2e-146 525.0 Lactobacillaceae sua5 2.7.7.87 ko:K07566 R10463 RC00745 ko00000,ko01000,ko03009,ko03016 Bacteria 1U3HQ@1239,3F9DB@33958,4HFGZ@91061,COG0009@1,COG0009@2 NA|NA|NA J Telomere recombination KIAJIJGH_00081 334390.LAF_1020 3.8e-29 134.8 Lactobacillaceae ybbM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 ko:K02069 M00211 ko00000,ko00002,ko02000 9.B.25.1 Bacteria 1UY1N@1239,3F4P1@33958,4HDM4@91061,COG0390@1,COG0390@2 NA|NA|NA S Uncharacterised protein family (UPF0014) KIAJIJGH_00083 158822.LH89_10875 5.9e-57 227.3 Gammaproteobacteria Bacteria 1QCKC@1224,1T2V3@1236,COG4221@1,COG4221@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family KIAJIJGH_00084 334390.LAF_0960 1.4e-27 128.3 Bacteria Bacteria COG4221@1,COG4221@2 NA|NA|NA IQ oxidoreductase activity KIAJIJGH_00086 334390.LAF_0959 3.2e-49 200.7 Lactobacillaceae Bacteria 1V45R@1239,3F7P2@33958,4HQY8@91061,COG0716@1,COG0716@2 NA|NA|NA C Flavodoxin KIAJIJGH_00087 334390.LAF_0958 3.8e-157 560.8 Lactobacillaceae yicL Bacteria 1TR6G@1239,3F423@33958,4HAMD@91061,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family KIAJIJGH_00088 334390.LAF_0957 3.9e-107 394.0 Lactobacillaceae ko:K04763 ko00000,ko03036 Bacteria 1V2RX@1239,3F4SP@33958,4IEJ7@91061,COG0582@1,COG0582@2 NA|NA|NA L Integrase KIAJIJGH_00089 334390.LAF_0956 3.3e-45 188.3 Bacteria Bacteria COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator KIAJIJGH_00090 334390.LAF_0148 8.5e-54 216.1 Lactobacillaceae 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 R03470 RC00938 ko00000,ko00001,ko01000 Bacteria 1VFY0@1239,3F88I@33958,4IBY8@91061,COG0599@1,COG0599@2 NA|NA|NA O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity KIAJIJGH_00091 334390.LAF_0149 7.1e-44 185.3 Lactobacillaceae Bacteria 1U8KN@1239,29QSW@1,30BSR@2,3FB34@33958,4IIIM@91061 NA|NA|NA KIAJIJGH_00092 334390.LAF_0150 1.5e-264 918.7 Lactobacillaceae isdH ko:K13730 ko05100,map05100 ko00000,ko00001 Bacteria 1VES7@1239,3F71K@33958,4HIEC@91061,COG5386@1,COG5386@2 NA|NA|NA M Iron Transport-associated domain KIAJIJGH_00093 334390.LAF_0151 3e-94 351.7 Lactobacillaceae ko:K14193 ko05150,map05150 ko00000,ko00001 Bacteria 1VES7@1239,3F6SK@33958,4HIEC@91061,COG5386@1,COG5386@2 NA|NA|NA M Iron Transport-associated domain KIAJIJGH_00094 334390.LAF_0152 4.8e-149 533.9 Lactobacillaceae isdE ko:K02016 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 1UIJ9@1239,3F4ZN@33958,4HDDF@91061,COG0614@1,COG0614@2 NA|NA|NA P Periplasmic binding protein KIAJIJGH_00095 334390.LAF_0153 1.1e-151 542.7 Lactobacillaceae isdF ko:K02015 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 1TPX6@1239,3F4T9@33958,4H9QQ@91061,COG0609@1,COG0609@2 NA|NA|NA U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily KIAJIJGH_00096 334390.LAF_0154 4.6e-140 503.8 Lactobacillaceae fhuC 3.6.3.34 ko:K02013 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 Bacteria 1TP2Q@1239,3F4NB@33958,4HCKS@91061,COG1120@1,COG1120@2 NA|NA|NA HP ABC transporter, ATP-binding protein KIAJIJGH_00097 334390.LAF_0155 3.8e-235 820.5 Lactobacillaceae kgtP ko:K03761 ko00000,ko02000 2.A.1.6.2 Bacteria 1TQIJ@1239,3F3N4@33958,4HAM0@91061,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter KIAJIJGH_00098 334390.LAF_0158 1.6e-157 562.0 Lactobacillaceae xth GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPFB@1239,3F4GK@33958,4HAIU@91061,COG0708@1,COG0708@2 NA|NA|NA L exodeoxyribonuclease III KIAJIJGH_00099 334390.LAF_0673 3.7e-28 132.9 Lactobacillaceae Bacteria 1UHY6@1239,3FBS3@33958,4ISAK@91061,COG4932@1,COG4932@2 NA|NA|NA M domain protein KIAJIJGH_00100 334390.LAF_0157 2.2e-27 128.6 Lactobacillaceae Bacteria 1U78P@1239,2DIUI@1,3045J@2,3F94E@33958,4IH3J@91061 NA|NA|NA KIAJIJGH_00101 334390.LAF_1573 1.5e-124 452.2 Lactobacillaceae Bacteria 1V2VJ@1239,28MIG@1,2ZAV8@2,3F7P0@33958,4HHCS@91061 NA|NA|NA S EcsC protein family KIAJIJGH_00102 1246.JMEA01000023_gene791 1.9e-26 124.4 Leuconostocaceae tnp ko:K07498 ko00000 Bacteria 1TTKR@1239,4AXG2@81850,4HCB4@91061,COG3316@1,COG3316@2 NA|NA|NA L DDE domain KIAJIJGH_00103 1291743.LOSG293_590030 2.2e-49 201.1 Lactobacillaceae yqeB Bacteria 1V717@1239,2AK1X@1,31ARI@2,3F6WW@33958,4HIQ9@91061 NA|NA|NA S Pyrimidine dimer DNA glycosylase KIAJIJGH_00104 568703.LGG_00464 5.7e-177 626.7 Lactobacillaceae Bacteria 1TRSF@1239,3F3WY@33958,4HTRR@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family KIAJIJGH_00105 498761.HM1_0624 1.6e-10 71.6 Clostridia Bacteria 1VEM0@1239,24QPN@186801,COG3655@1,COG3655@2 NA|NA|NA K Psort location Cytoplasmic, score KIAJIJGH_00106 565655.ECBG_03020 1.8e-161 575.5 Enterococcaceae dcm_2 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Bacteria 1TPNE@1239,4B0NU@81852,4HB9C@91061,COG0270@1,COG0270@2 NA|NA|NA L C-5 cytosine-specific DNA methylase KIAJIJGH_00107 936589.HMPREF1521_1522 1.5e-153 549.3 Firmicutes dcm 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Bacteria 1TSNX@1239,COG0270@1,COG0270@2 NA|NA|NA H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family KIAJIJGH_00108 565655.ECBG_03022 3.7e-79 302.0 Firmicutes Bacteria 1UQD1@1239,COG3886@1,COG3886@2 NA|NA|NA L NgoFVII restriction endonuclease KIAJIJGH_00112 334390.LAF_1054 2e-288 997.7 Lactobacillaceae gshF 6.3.2.2 ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 M00118,M00582 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TPGX@1239,3F506@33958,4HAMJ@91061,COG2918@1,COG2918@2 NA|NA|NA H Belongs to the glutamate--cysteine ligase type 1 family KIAJIJGH_00113 334390.LAF_1052 2.2e-96 358.2 Lactobacillaceae Bacteria 1VKIA@1239,3F86G@33958,4HNUJ@91061,COG4767@1,COG4767@2 NA|NA|NA V VanZ like family KIAJIJGH_00114 334390.LAF_1051 4.4e-222 776.9 Lactobacillaceae aspB GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052 RC00006,RC00025 ko00000,ko00001,ko01000,ko01007 iHN637.CLJU_RS06550 Bacteria 1TP0J@1239,3F3MX@33958,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase KIAJIJGH_00115 334390.LAF_1050 2.5e-61 241.1 Lactobacillaceae yneR Bacteria 1U71X@1239,3F8VF@33958,4IGWD@91061,COG4841@1,COG4841@2 NA|NA|NA KIAJIJGH_00116 334390.LAF_1049 2.2e-182 644.8 Lactobacillaceae ko:K02525 ko00000,ko03000 Bacteria 1TQSY@1239,3FC5E@33958,4HAJI@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator, LacI family KIAJIJGH_00117 334390.LAF_1048 3.2e-229 800.8 Lactobacillaceae gntT GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008028,GO:0008150,GO:0008509,GO:0008514,GO:0008643,GO:0015075,GO:0015128,GO:0015144,GO:0015318,GO:0015711,GO:0015718,GO:0015849,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034219,GO:0034220,GO:0035429,GO:0042873,GO:0042879,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039 ko:K03299,ko:K06155 ko00000,ko02000 2.A.8,2.A.8.1.4 Bacteria 1TQ14@1239,3F3V0@33958,4HB0Y@91061,COG2610@1,COG2610@2 NA|NA|NA EG Gluconate KIAJIJGH_00118 334390.LAF_1047 1.2e-288 998.4 Lactobacillaceae gntK 2.7.1.12,2.7.1.17 ko:K00851,ko:K00854 ko00030,ko00040,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map01100,map01110,map01120,map01130,map01200 M00014 R01639,R01737 RC00002,RC00017,RC00538 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ1I@1239,3F4R2@33958,4H9W6@91061,COG1070@1,COG1070@2 NA|NA|NA G Belongs to the FGGY kinase family KIAJIJGH_00119 334390.LAF_1046 2e-169 601.7 Lactobacillaceae mutR ko:K20373,ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Bacteria 1VD87@1239,3F7WI@33958,4HKR0@91061,COG1396@1,COG1396@2 NA|NA|NA K Transcriptional activator, Rgg GadR MutR family KIAJIJGH_00120 525309.HMPREF0494_1303 5.8e-11 74.3 Lactobacillaceae traP GO:0005575,GO:0016020 1.14.99.57,6.2.1.3 ko:K01897,ko:K21481 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 1V501@1239,3F3UU@33958,4HHA2@91061,COG2329@1,COG2329@2 NA|NA|NA S enzyme involved in biosynthesis of extracellular polysaccharides KIAJIJGH_00121 334390.LAF_1045 1.6e-76 292.0 Bacteria 3.6.3.6 ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 3.A.3.3 Bacteria COG0474@1,COG0474@2 NA|NA|NA P ATPase, P-type transporting, HAD superfamily, subfamily IC KIAJIJGH_00123 334390.LAF_1037 4.2e-80 303.9 Lactobacillaceae copY Bacteria 1VA7Q@1239,3F7D0@33958,4HKGF@91061,COG3682@1,COG3682@2 NA|NA|NA K Copper transport repressor CopY TcrY KIAJIJGH_00124 334390.LAF_1036 1.1e-40 172.2 Lactobacillaceae Bacteria 1U6DN@1239,29PBP@1,30A9X@2,3F7NV@33958,4IG5D@91061 NA|NA|NA KIAJIJGH_00125 334390.LAF_1035 2.6e-169 601.3 Lactobacillaceae Bacteria 1V3T9@1239,3FC7F@33958,4HU07@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family KIAJIJGH_00126 334390.LAF_1034 9.8e-129 466.1 Lactobacillaceae 1.14.12.17 ko:K02639,ko:K05916 ko00195,ko05132,map00195,map05132 ko00000,ko00001,ko00194,ko01000 Bacteria 1VF2T@1239,3F9TF@33958,4I4BK@91061,COG1018@1,COG1018@2 NA|NA|NA C Oxidoreductase NAD-binding domain KIAJIJGH_00127 334390.LAF_1033 9.5e-311 1072.0 Lactobacillaceae ubiB ko:K03688 ko00000 Bacteria 1TPIV@1239,3F51C@33958,4HBW3@91061,COG0661@1,COG0661@2 NA|NA|NA S ABC1 family KIAJIJGH_00128 334390.LAF_1032 1.1e-103 382.5 Lactobacillaceae wecD3 Bacteria 1V6Z8@1239,3F6WQ@33958,4HMP7@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) family KIAJIJGH_00129 334390.LAF_1031 4.1e-68 263.8 Lactobacillaceae Bacteria 1V7D7@1239,3F6XZ@33958,4HIGP@91061,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily KIAJIJGH_00130 334390.LAF_1030 4.9e-55 220.3 Bacteria crcB ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria COG0239@1,COG0239@2 NA|NA|NA D Important for reducing fluoride concentration in the cell, thus reducing its toxicity KIAJIJGH_00131 334390.LAF_1029 1.3e-54 218.8 Lactobacillaceae crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 ko:K06199 ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 Bacteria 1VM30@1239,3F8A8@33958,4HRC4@91061,COG0239@1,COG0239@2 NA|NA|NA U Important for reducing fluoride concentration in the cell, thus reducing its toxicity KIAJIJGH_00132 1136177.KCA1_1516 1.3e-31 142.5 Lactobacillaceae rocF 3.5.3.1,3.5.3.11 ko:K01476,ko:K01480 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 M00029,M00133,M00134 R00551,R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 Bacteria 1V45X@1239,3F628@33958,4HU4J@91061,COG0010@1,COG0010@2 NA|NA|NA E Arginase family KIAJIJGH_00133 334390.LAF_1635 1.4e-50 205.3 Lactobacillaceae ybjQ Bacteria 1VADM@1239,3F6YC@33958,4HKGZ@91061,COG0393@1,COG0393@2 NA|NA|NA S Belongs to the UPF0145 family KIAJIJGH_00134 873449.STRCR_1466 1.6e-72 279.3 Bacilli dxs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0008661,GO:0009058,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901363,GO:1901576,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP37@1239,4H9QW@91061,COG1154@1,COG1154@2 NA|NA|NA H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) KIAJIJGH_00135 334390.LAF_1631 8e-121 440.3 Lactobacillaceae bm3R1 ko:K09017 ko00000,ko03000 Bacteria 1UV8F@1239,3F87D@33958,4I430@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family KIAJIJGH_00136 334390.LAF_1631 9.5e-39 166.0 Lactobacillaceae bm3R1 ko:K09017 ko00000,ko03000 Bacteria 1UV8F@1239,3F87D@33958,4I430@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family KIAJIJGH_00137 334390.LAF_1630 0.0 1134.8 Lactobacillaceae yhcA ko:K02003,ko:K02004,ko:K05685 ko02010,map02010 M00258,M00709 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.122.1,3.A.1.122.12 Bacteria 1TPBJ@1239,3F44P@33958,4HBK7@91061,COG0577@1,COG0577@2,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein KIAJIJGH_00138 334390.LAF_1629 1.8e-49 202.2 Lactobacillaceae Bacteria 1VBTI@1239,3F7N4@33958,4HKRR@91061,COG3976@1,COG3976@2 NA|NA|NA S FMN_bind KIAJIJGH_00139 1123303.AQVD01000003_gene1136 1.2e-66 260.0 Bacilli apbE 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria 1VVZ1@1239,4HWJX@91061,COG1477@1,COG1477@2 NA|NA|NA H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein KIAJIJGH_00140 1123303.AQVD01000003_gene1137 9.7e-135 486.9 Bacteria Bacteria COG4097@1,COG4097@2 NA|NA|NA P nitric oxide dioxygenase activity KIAJIJGH_00141 936140.AEOT01000002_gene2115 1.5e-48 199.1 Lactobacillaceae XK27_08850 ko:K19055 ko00000,ko01000,ko03016 Bacteria 1UPN5@1239,3FC0G@33958,4IV7V@91061,COG3760@1,COG3760@2 NA|NA|NA S Aminoacyl-tRNA editing domain KIAJIJGH_00142 334390.LAF_1628 7.2e-77 294.7 Lactobacillaceae ko:K02004,ko:K03646 M00258 ko00000,ko00002,ko02000 2.C.1.2,3.A.1 Bacteria 1UJIE@1239,3FBV7@33958,4ITAB@91061,COG0624@1,COG0624@2,COG3064@1,COG3064@2 NA|NA|NA M Membrane KIAJIJGH_00143 334390.LAF_1628 1.2e-66 259.6 Lactobacillaceae ko:K02004,ko:K03646 M00258 ko00000,ko00002,ko02000 2.C.1.2,3.A.1 Bacteria 1UJIE@1239,3FBV7@33958,4ITAB@91061,COG0624@1,COG0624@2,COG3064@1,COG3064@2 NA|NA|NA M Membrane KIAJIJGH_00144 1035184.HMPREF1042_1541 9.3e-24 115.9 Streptococcus anginosus group XK27_06785 ko:K02003,ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQC9@1239,42D91@671232,4HB8D@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter KIAJIJGH_00145 334390.LAF_1627 5.4e-101 373.6 Bacilli Bacteria 1VDR5@1239,4HMPB@91061,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator KIAJIJGH_00146 334390.LAF_1626 0.0 1182.5 Lactobacillaceae Bacteria 1UYWB@1239,3F5AG@33958,4HTZD@91061,COG1807@1,COG1807@2 NA|NA|NA M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family KIAJIJGH_00147 334390.LAF_0059 8.2e-173 613.2 Lactobacillaceae ko:K07496 ko00000 Bacteria 1TRNY@1239,3F55P@33958,4HBKP@91061,COG0675@1,COG0675@2 NA|NA|NA L transposase, IS605 OrfB family KIAJIJGH_00148 334390.LAF_0134 1.4e-42 179.5 Lactobacillaceae ko:K07491 ko00000 Bacteria 1V4ET@1239,3F7IF@33958,4HH13@91061,COG1943@1,COG1943@2 NA|NA|NA L Transposase IS200 like KIAJIJGH_00149 525309.HMPREF0494_0873 1.4e-242 845.9 Lactobacillaceae Bacteria 1V3AR@1239,3F5UT@33958,4ISZR@91061,COG1502@1,COG1502@2 NA|NA|NA I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol KIAJIJGH_00150 334390.LAF_1625 1.3e-232 812.0 Lactobacillaceae argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 iJN678.argG,iSB619.SA_RS04675 Bacteria 1TP3X@1239,3F46X@33958,4HA1E@91061,COG0137@1,COG0137@2 NA|NA|NA E Belongs to the argininosuccinate synthase family. Type 1 subfamily KIAJIJGH_00151 334390.LAF_1624 7.3e-261 906.0 Lactobacillaceae argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TNZ6@1239,3F4PF@33958,4HB24@91061,COG0165@1,COG0165@2 NA|NA|NA E argininosuccinate lyase KIAJIJGH_00152 1291743.LOSG293_250100 1.1e-50 206.5 Lactobacillaceae lacA Bacteria 1TSQQ@1239,3F73Z@33958,4HJJ7@91061,COG0110@1,COG0110@2 NA|NA|NA S transferase hexapeptide repeat KIAJIJGH_00153 334390.LAF_1622 2.6e-157 561.2 Lactobacillaceae ko:K07107 ko00000,ko01000 Bacteria 1VAGM@1239,3F7PP@33958,4HIVC@91061,COG0494@1,COG0494@2,COG0824@1,COG0824@2 NA|NA|NA L Thioesterase-like superfamily KIAJIJGH_00155 334390.LAF_1621 7.2e-83 313.2 Lactobacillaceae Bacteria 1V955@1239,3F4UW@33958,4IEX8@91061,COG0655@1,COG0655@2 NA|NA|NA S NADPH-dependent FMN reductase KIAJIJGH_00156 334390.LAF_1620 2.3e-241 841.3 Lactobacillaceae yfnA ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ4K@1239,3FCAJ@33958,4HA32@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid KIAJIJGH_00157 334390.LAF_1619 7.4e-242 842.8 Lactobacillaceae gabT 2.6.1.19 ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1VS6F@1239,3F569@33958,4H9M7@91061,COG0160@1,COG0160@2 NA|NA|NA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family KIAJIJGH_00159 334390.LAF_1617 7.5e-153 546.6 Lactobacillaceae mleP3 ko:K07088 ko00000 Bacteria 1UY4N@1239,3FBIX@33958,4HEPU@91061,COG0679@1,COG0679@2 NA|NA|NA S Membrane transport protein KIAJIJGH_00160 334390.LAF_1616 1.1e-52 212.2 Lactobacillaceae trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 1VA3Y@1239,3F6Y3@33958,4HKKX@91061,COG3118@1,COG3118@2 NA|NA|NA O Belongs to the thioredoxin family KIAJIJGH_00161 334390.LAF_1615 1.6e-252 878.2 Lactobacillaceae gor 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 R00094,R00115 RC00011 ko00000,ko00001,ko01000 Bacteria 1VTHV@1239,3FC6U@33958,4HV84@91061,COG1249@1,COG1249@2 NA|NA|NA C pyridine nucleotide-disulfide oxidoreductase KIAJIJGH_00162 334390.LAF_1614 7.4e-206 723.0 Lactobacillaceae Bacteria 1TRNU@1239,3FCA6@33958,4HCSX@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily KIAJIJGH_00163 334390.LAF_1613 6.9e-78 296.6 Lactobacillaceae ycsG Bacteria 1TP0Q@1239,3F582@33958,4HAYE@91061,COG1914@1,COG1914@2 NA|NA|NA P Natural resistance-associated macrophage protein KIAJIJGH_00164 1423743.JCM14108_3042 1.3e-136 493.0 Lactobacillaceae 3.6.4.12 ko:K02314,ko:K02316,ko:K17680 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03029,ko03032 Bacteria 1V1I5@1239,3F7KN@33958,4IG43@91061,COG0305@1,COG0305@2,COG0358@1,COG0358@2 NA|NA|NA L DnaB-like helicase C terminal domain KIAJIJGH_00165 908339.HMPREF9265_1682 6.5e-260 902.9 Lactobacillaceae aldA GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004029,GO:0004777,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006004,GO:0006082,GO:0006105,GO:0006520,GO:0006536,GO:0006538,GO:0006540,GO:0006807,GO:0008150,GO:0008152,GO:0008911,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009448,GO:0009450,GO:0009987,GO:0016043,GO:0016052,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0019299,GO:0019301,GO:0019317,GO:0019318,GO:0019320,GO:0019752,GO:0022607,GO:0032787,GO:0036094,GO:0042133,GO:0042135,GO:0042354,GO:0042355,GO:0042802,GO:0043436,GO:0043648,GO:0043649,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046395,GO:0048037,GO:0050569,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051287,GO:0051289,GO:0055114,GO:0065003,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.21,1.2.1.22 ko:K07248 ko00620,ko00630,ko01120,map00620,map00630,map01120 R00203,R01333,R01446 RC00080,RC00104,RC00242 ko00000,ko00001,ko01000 iAF1260.b1415,iBWG_1329.BWG_1242,iECDH10B_1368.ECDH10B_1541,iECDH1ME8569_1439.ECDH1ME8569_1358,iEcDH1_1363.EcDH1_2230,iJO1366.b1415,iJR904.b1415,iY75_1357.Y75_RS07435 Bacteria 1TP4S@1239,3F47F@33958,4H9MF@91061,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family KIAJIJGH_00166 525309.HMPREF0494_0411 6.2e-202 709.9 Lactobacillaceae adhC 1.1.1.90 ko:K00055,ko:K06898 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 M00537,M00538 R01763,R02611,R04304,R05282,R05347,R05348 RC00087,RC00116 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP8E@1239,3F3QP@33958,4HAH9@91061,COG1062@1,COG1062@2 NA|NA|NA C Zn-dependent alcohol dehydrogenases, class III KIAJIJGH_00167 334390.LAF_1768 3.1e-124 451.1 Lactobacillaceae Bacteria 1V8E3@1239,3F4H9@33958,4HJ08@91061,COG2364@1,COG2364@2 NA|NA|NA S Membrane KIAJIJGH_00168 334390.LAF_0024 1.9e-250 871.3 Lactobacillaceae malT ko:K16211 ko00000,ko02000 2.A.2.6 Bacteria 1TRP7@1239,3F3YZ@33958,4HCUK@91061,COG2211@1,COG2211@2 NA|NA|NA G Major Facilitator KIAJIJGH_00169 334390.LAF_0023 6.1e-45 186.4 Lactobacillaceae malR ko:K02529 ko00000,ko03000 Bacteria 1TPZM@1239,3F4TM@33958,4H9ZT@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator, LacI family KIAJIJGH_00170 334390.LAF_0022 5.7e-71 273.5 Lactobacillaceae Bacteria 1V6FK@1239,3F73Q@33958,4HKZD@91061,COG1959@1,COG1959@2 NA|NA|NA K Transcriptional regulator KIAJIJGH_00171 334390.LAF_0020 1.8e-59 235.3 Lactobacillaceae htrA GO:0008150,GO:0009266,GO:0009628,GO:0050896 3.4.21.107 ko:K04691,ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1TRM8@1239,3F45X@33958,4HA31@91061,COG0265@1,COG0265@2 NA|NA|NA O serine protease KIAJIJGH_00172 334390.LAF_1663 1.3e-168 599.0 Lactobacillaceae Bacteria 1V7ET@1239,2C6F0@1,32RH8@2,3F4UC@33958,4HJDI@91061 NA|NA|NA KIAJIJGH_00174 334390.LAF_1665 3.4e-82 310.8 Lactobacillaceae zur GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K02076,ko:K03711 ko00000,ko03000 Bacteria 1V6RI@1239,3F6W3@33958,4HIGM@91061,COG0735@1,COG0735@2 NA|NA|NA P Belongs to the Fur family KIAJIJGH_00175 334390.LAF_1666 1.7e-105 388.7 Lactobacillaceae gmk2 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1V8PW@1239,3F6N3@33958,4HJCB@91061,COG0194@1,COG0194@2 NA|NA|NA F Guanylate kinase KIAJIJGH_00176 334390.LAF_1667 5.9e-73 280.0 Lactobacillaceae apfA 2.7.7.72,3.6.1.61 ko:K00974,ko:K18445 ko00230,ko03013,map00230,map03013 R00184,R09382,R09383,R09384,R09386 RC00002,RC00078 ko00000,ko00001,ko01000,ko03016 Bacteria 1VED7@1239,3FBDM@33958,4HRPV@91061,COG1051@1,COG1051@2 NA|NA|NA F Nudix hydrolase KIAJIJGH_00177 944562.HMPREF9102_1688 1.1e-205 722.6 Lactobacillaceae yfnA ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ4K@1239,3F3QY@33958,4HA66@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino Acid KIAJIJGH_00178 334390.LAF_1668 0.0 1617.8 Lactobacillaceae pepX 3.4.14.11 ko:K01281 ko00000,ko01000,ko01002 Bacteria 1TT78@1239,3F44E@33958,4HBA0@91061,COG2936@1,COG2936@2 NA|NA|NA E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline KIAJIJGH_00179 334390.LAF_1669 3.1e-178 630.9 Lactobacillaceae 3.4.11.5 ko:K01259 ko00330,map00330 R00135 ko00000,ko00001,ko01000,ko01002 Bacteria 1UJIF@1239,3FBV8@33958,4ITAC@91061,COG0596@1,COG0596@2 NA|NA|NA E Releases the N-terminal proline from various substrates KIAJIJGH_00181 511437.Lbuc_2420 5.7e-40 170.2 Lactobacillaceae cps2D 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS00780 Bacteria 1V34Y@1239,3F5GY@33958,4HCJE@91061,COG0451@1,COG0451@2 NA|NA|NA M RmlD substrate binding domain KIAJIJGH_00182 511437.Lbuc_2419 1.3e-93 349.4 Lactobacillaceae tuaA Bacteria 1TP7M@1239,3F5PC@33958,4HB15@91061,COG2148@1,COG2148@2 NA|NA|NA M Bacterial sugar transferase KIAJIJGH_00183 658088.HMPREF0987_02496 5.6e-30 136.7 unclassified Lachnospiraceae Bacteria 1TQJC@1239,25B10@186801,27JTT@186928,COG0667@1,COG0667@2 NA|NA|NA C Aldo/keto reductase family KIAJIJGH_00186 257314.LJ_1158 1.6e-85 322.8 Lactobacillaceae Bacteria 1TPM1@1239,3F3PW@33958,4HARE@91061,COG0656@1,COG0656@2 NA|NA|NA C Aldo keto reductase KIAJIJGH_00187 575594.ACOH01000002_gene1011 8.3e-80 303.9 Lactobacillaceae Bacteria 1TRHF@1239,3F3VA@33958,4HBXH@91061,COG4221@1,COG4221@2 NA|NA|NA S Belongs to the short-chain dehydrogenases reductases (SDR) family KIAJIJGH_00188 525365.HMPREF0548_0513 5.8e-82 310.5 Lactobacillaceae Bacteria 1USYC@1239,3F5NJ@33958,4HBXD@91061,COG0596@1,COG0596@2 NA|NA|NA S Alpha/beta hydrolase family KIAJIJGH_00189 334390.LAF_0142 7.3e-118 429.9 Lactobacillaceae pnb Bacteria 1V6AG@1239,3F6YM@33958,4HN5N@91061,COG0778@1,COG0778@2 NA|NA|NA C nitroreductase KIAJIJGH_00190 1423790.BN53_05245 3.2e-33 148.7 Lactobacillaceae flpA 4.1.99.16,4.2.3.22,4.2.3.75 ko:K10187,ko:K21562 ko00909,ko01100,ko01110,map00909,map01100,map01110 R07647,R07648,R08543,R09487 RC01832,RC02159,RC02160,RC02183,RC02425,RC02552 ko00000,ko00001,ko01000,ko03000 Bacteria 1TVBM@1239,3F4PI@33958,4HEJG@91061,COG0664@1,COG0664@2 NA|NA|NA K helix_turn_helix, cAMP Regulatory protein KIAJIJGH_00191 525318.HMPREF0497_0612 2e-43 181.8 Lactobacillaceae Bacteria 1V3SS@1239,3F6UD@33958,4HI9G@91061,COG1942@1,COG1942@2 NA|NA|NA S Tautomerase enzyme KIAJIJGH_00192 1203076.CAKF01000024_gene920 3.6e-29 135.2 Lactobacillaceae Bacteria 1W05T@1239,2DR8S@1,33AQ2@2,3F63G@33958,4HZ0I@91061 NA|NA|NA S Domain of unknown function (DUF4767) KIAJIJGH_00194 1235798.C817_00125 5.1e-58 232.3 Clostridia pglK GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K19418 ko00000,ko02000 Bacteria 1TQBD@1239,24CYT@186801,COG2244@1,COG2244@2 NA|NA|NA S polysaccharide biosynthetic process KIAJIJGH_00195 334390.LAF_1392 1.7e-97 362.1 Lactobacillaceae Bacteria 1V2M1@1239,3FCAQ@33958,4HFPD@91061,COG4684@1,COG4684@2 NA|NA|NA S Pfam:DUF3816 KIAJIJGH_00196 994573.T472_0203955 8.3e-24 118.2 Clostridia Bacteria 1V2WH@1239,24GXU@186801,COG4974@1,COG4974@2 NA|NA|NA L Plasmid pRiA4b ORF-3-like protein KIAJIJGH_00197 334390.LAF_0362 1e-15 88.2 Lactobacillaceae Bacteria 1U6K5@1239,29PH2@1,30AF7@2,3F82T@33958,4IGCV@91061 NA|NA|NA KIAJIJGH_00198 334390.LAF_0363 1e-190 672.5 Lactobacillaceae gap GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009986,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019362,GO:0019637,GO:0019674,GO:0022610,GO:0034641,GO:0036094,GO:0043891,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044464,GO:0044650,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051704,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0097159,GO:0140030,GO:0140032,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 iJR904.b1416,iJR904.b1417 Bacteria 1TNYU@1239,3F3JS@33958,4H9NS@91061,COG0057@1,COG0057@2 NA|NA|NA G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family KIAJIJGH_00199 334390.LAF_0364 6.2e-224 783.1 Lactobacillaceae pgk GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iSB619.SA_RS04145 Bacteria 1TP3H@1239,3F3SC@33958,4H9R3@91061,COG0126@1,COG0126@2 NA|NA|NA F Belongs to the phosphoglycerate kinase family KIAJIJGH_00200 334390.LAF_0365 3.1e-144 517.7 Lactobacillaceae tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iHN637.CLJU_RS19265 Bacteria 1TP2F@1239,3F494@33958,4HAPT@91061,COG0149@1,COG0149@2 NA|NA|NA G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) KIAJIJGH_00201 334390.LAF_0366 1e-248 865.5 Lactobacillaceae eno GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Bacteria 1TP2S@1239,3F3JP@33958,4HAKI@91061,COG0148@1,COG0148@2 NA|NA|NA G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis KIAJIJGH_00202 334390.LAF_0367 1.5e-253 881.7 Lactobacillaceae yifK GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03293 ko00000 2.A.3.1 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease KIAJIJGH_00203 334390.LAF_0368 2.2e-290 1004.2 Lactobacillaceae clcA GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006821,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015672,GO:0015698,GO:0015706,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0031404,GO:0034220,GO:0042802,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071705,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 ko:K03281,ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4,2.A.49 iAF1260.b0155,iB21_1397.B21_00153,iBWG_1329.BWG_0148,iE2348C_1286.E2348C_0162,iEC042_1314.EC042_0155,iEC55989_1330.EC55989_0149,iECBD_1354.ECBD_3463,iECDH10B_1368.ECDH10B_0135,iECDH1ME8569_1439.ECDH1ME8569_0149,iECD_1391.ECD_00154,iECIAI1_1343.ECIAI1_0153,iECO103_1326.ECO103_0155,iECSE_1348.ECSE_0156,iECUMN_1333.ECUMN_0152,iECW_1372.ECW_m0152,iEKO11_1354.EKO11_3761,iETEC_1333.ETEC_0151,iEcDH1_1363.EcDH1_3447,iEcE24377_1341.EcE24377A_0160,iEcolC_1368.EcolC_3504,iJO1366.b0155,iSSON_1240.SSON_0167,iUMNK88_1353.UMNK88_159,iWFL_1372.ECW_m0152,iY75_1357.Y75_RS00790,iZ_1308.Z0166 Bacteria 1TPX0@1239,3F3MU@33958,4HD2H@91061,COG0038@1,COG0038@2,COG0569@1,COG0569@2 NA|NA|NA P chloride KIAJIJGH_00204 334390.LAF_0369 4.5e-33 146.7 Lactobacillaceae secG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1VEQR@1239,3F7IQ@33958,4HNKC@91061,COG1314@1,COG1314@2 NA|NA|NA U Preprotein translocase KIAJIJGH_00205 334390.LAF_0370 0.0 1463.7 Lactobacillaceae rnr ko:K12573,ko:K12585 ko03018,map03018 M00391 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Bacteria 1TQ1G@1239,3F4EC@33958,4HBBH@91061,COG0557@1,COG0557@2 NA|NA|NA J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs KIAJIJGH_00206 334390.LAF_0371 2.9e-84 317.8 Lactobacillaceae smpB GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 ko:K03664 ko00000 Bacteria 1V3IJ@1239,3F65B@33958,4HGZX@91061,COG0691@1,COG0691@2 NA|NA|NA J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA KIAJIJGH_00207 334390.LAF_0372 2.7e-108 397.9 Lactobacillaceae yxjI ko:K21429 ko00000,ko01002 Bacteria 1V8EY@1239,3F698@33958,4HMMS@91061,COG4894@1,COG4894@2 NA|NA|NA KIAJIJGH_00208 334390.LAF_0373 2.8e-136 491.1 Lactobacillaceae ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPSN@1239,3F3W0@33958,4HBTR@91061,COG0692@1,COG0692@2 NA|NA|NA L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine KIAJIJGH_00209 334390.LAF_0374 2.4e-178 631.3 Lactobacillaceae pta 2.3.1.8,3.6.3.21 ko:K00625,ko:K02028,ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00236,M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 iSB619.SA_RS03155 Bacteria 1TPQ0@1239,3F3MW@33958,4H9VH@91061,COG0280@1,COG0280@2 NA|NA|NA C phosphate acetyltransferase KIAJIJGH_00210 334390.LAF_0375 2.9e-81 307.8 Lactobacillaceae ydiB GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.1.221,5.1.1.1 ko:K01775,ko:K06925,ko:K07102 ko00473,ko00520,ko01100,ko01502,map00473,map00520,map01100,map01502 R00401,R08968,R11024 RC00002,RC00078,RC00285 ko00000,ko00001,ko01000,ko01011,ko03016 Bacteria 1V6CV@1239,3F3MR@33958,4HIIF@91061,COG0802@1,COG0802@2 NA|NA|NA O Hydrolase, P-loop family KIAJIJGH_00211 334390.LAF_0376 7.3e-89 333.2 Lactobacillaceae Bacteria 1V22A@1239,3F7BU@33958,4ITA6@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain KIAJIJGH_00212 334390.LAF_0377 1.3e-101 375.6 Lactobacillaceae dnaQ 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1V57H@1239,3F42Z@33958,4HI1V@91061,COG0847@1,COG0847@2 NA|NA|NA L DNA polymerase III KIAJIJGH_00213 334390.LAF_0378 5.7e-166 590.1 Lactobacillaceae murB 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 Bacteria 1TP3W@1239,3F40T@33958,4HAD8@91061,COG0812@1,COG0812@2 NA|NA|NA M Cell wall formation KIAJIJGH_00214 334390.LAF_0379 7.8e-149 533.1 Lactobacillaceae dacA GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 ko:K18672 ko00000,ko01000 Bacteria 1TPRW@1239,3F4N3@33958,4H9XZ@91061,COG1624@1,COG1624@2 NA|NA|NA S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria KIAJIJGH_00215 334390.LAF_0380 9.1e-116 423.3 Lactobacillaceae ybbR GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 Bacteria 1TSIV@1239,3F41C@33958,4HD8Y@91061,COG4856@1,COG4856@2 NA|NA|NA S YbbR-like protein KIAJIJGH_00216 334390.LAF_0381 2.5e-253 880.9 Lactobacillaceae glmM GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 R02060 RC00408 ko00000,ko00001,ko01000 iSB619.SA_RS11275,iSBO_1134.SBO_3206 Bacteria 1TP1X@1239,3F3W5@33958,4HB16@91061,COG1109@1,COG1109@2 NA|NA|NA G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate KIAJIJGH_00217 334390.LAF_0382 0.0 1182.9 Lactobacillaceae glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 iNJ661.Rv3436c,iSB619.SA_RS11245,iYO844.BSU01780 Bacteria 1TPGU@1239,3F467@33958,4H9R4@91061,COG0449@1,COG0449@2 NA|NA|NA M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source KIAJIJGH_00218 334390.LAF_0383 3.3e-52 210.7 Lactobacillaceae Bacteria 1VX4A@1239,2C26E@1,3424N@2,3F70Q@33958,4HXT9@91061 NA|NA|NA KIAJIJGH_00219 575594.ACOH01000010_gene1642 7.1e-211 740.3 Lactobacillaceae oatA Bacteria 1TPTG@1239,3F3WT@33958,4HB7R@91061,COG1835@1,COG1835@2 NA|NA|NA I Acyltransferase KIAJIJGH_00220 334390.LAF_0384 1.7e-148 531.9 Lactobacillaceae XK27_02985 Bacteria 1TR2E@1239,3FC89@33958,4HGA9@91061,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase KIAJIJGH_00221 334390.LAF_0385 2.4e-75 288.5 Lactobacillaceae lytE Bacteria 1VA10@1239,3FC14@33958,4HMUH@91061,COG1388@1,COG1388@2 NA|NA|NA M Lysin motif KIAJIJGH_00222 334390.LAF_0386 9.2e-160 569.7 Lactobacillaceae MA20_14895 Bacteria 1TQYA@1239,3F4TY@33958,4HCCP@91061,COG2855@1,COG2855@2 NA|NA|NA S Conserved hypothetical protein 698 KIAJIJGH_00223 334390.LAF_0387 2.7e-163 581.3 Lactobacillaceae Bacteria 1TSNI@1239,3FBIA@33958,4HDGS@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain KIAJIJGH_00224 1423814.HMPREF0549_0419 1.7e-131 475.7 Lactobacillaceae manA 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 Bacteria 1VRGI@1239,3F40I@33958,4HBFW@91061,COG1482@1,COG1482@2 NA|NA|NA G mannose-6-phosphate isomerase KIAJIJGH_00225 334390.LAF_0388 1.3e-148 532.3 Lactobacillaceae yitS Bacteria 1TSKD@1239,3FBEP@33958,4HC4E@91061,COG1307@1,COG1307@2 NA|NA|NA S EDD domain protein, DegV family KIAJIJGH_00226 334390.LAF_0389 6.5e-90 336.7 Lactobacillaceae racA ko:K11686,ko:K13640,ko:K18997 ko00000,ko03000,ko03036 Bacteria 1V7Z4@1239,3F6W4@33958,4HPH8@91061,COG0789@1,COG0789@2 NA|NA|NA K Domain of unknown function (DUF1836) KIAJIJGH_00227 334390.LAF_0390 2.3e-181 641.3 Lactobacillaceae yfeX ko:K07223 ko00000 Bacteria 1UY9Y@1239,3F45Z@33958,4HACQ@91061,COG2837@1,COG2837@2 NA|NA|NA P Peroxidase KIAJIJGH_00228 334390.LAF_0391 5.3e-181 640.2 Lactobacillaceae manL 2.7.1.191 ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 Bacteria 1TQJ4@1239,3F4PU@33958,4H9Z8@91061,COG2893@1,COG2893@2,COG3444@1,COG3444@2 NA|NA|NA G PTS system sorbose subfamily IIB component KIAJIJGH_00229 334390.LAF_0392 2.7e-122 444.9 Lactobacillaceae manY ko:K02795,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 Bacteria 1TPKK@1239,3F3V5@33958,4H9QI@91061,COG3715@1,COG3715@2 NA|NA|NA G PTS system KIAJIJGH_00230 334390.LAF_0393 7.4e-169 599.7 Lactobacillaceae manN ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 Bacteria 1TQA3@1239,3F3KR@33958,4HA3K@91061,COG3716@1,COG3716@2 NA|NA|NA G system, mannose fructose sorbose family IID component KIAJIJGH_00231 334390.LAF_0394 2.3e-56 224.6 Lactobacillaceae Bacteria 1V6KV@1239,3F719@33958,4HIMF@91061,COG4687@1,COG4687@2 NA|NA|NA S Domain of unknown function (DUF956) KIAJIJGH_00233 334390.LAF_0397 9.7e-132 476.1 Lactobacillaceae Bacteria 1TQUQ@1239,3F3QZ@33958,4HAXP@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator KIAJIJGH_00234 334390.LAF_0398 7.4e-251 872.8 Lactobacillaceae yclK 2.7.13.3 ko:K02484,ko:K07636,ko:K07642 ko02020,map02020 M00434,M00450,M00645,M00646,M00648 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TQ1H@1239,3FBSR@33958,4IS6U@91061,COG2770@1,COG2770@2,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase KIAJIJGH_00235 334390.LAF_0399 5.9e-152 543.5 Lactobacillaceae glcU ko:K05340 ko00000,ko02000 2.A.7.5 Bacteria 1TQBN@1239,3F4K2@33958,4HAVH@91061,COG4975@1,COG4975@2 NA|NA|NA U sugar transport KIAJIJGH_00236 334390.LAF_0400 2.7e-216 757.7 Lactobacillaceae xylR Bacteria 1TQCE@1239,3F540@33958,4HDE3@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family KIAJIJGH_00237 334390.LAF_0401 9.5e-253 879.0 Lactobacillaceae xylT Bacteria 1TREV@1239,3F3ZS@33958,4HAN1@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily KIAJIJGH_00238 334390.LAF_0402 1.9e-269 934.5 Lactobacillaceae xylA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 R00878,R01432 RC00376,RC00516 ko00000,ko00001,ko01000 iECO26_1355.ECO26_5036,iHN637.CLJU_RS08960,iPC815.YPO4038 Bacteria 1TQW2@1239,3F5ME@33958,4H9WG@91061,COG2115@1,COG2115@2 NA|NA|NA G Belongs to the xylose isomerase family KIAJIJGH_00239 334390.LAF_0403 4.9e-295 1019.6 Lactobacillaceae xylB 2.7.1.12,2.7.1.17 ko:K00851,ko:K00854 ko00030,ko00040,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map01100,map01110,map01120,map01130,map01200 M00014 R01639,R01737 RC00002,RC00017,RC00538 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ1I@1239,3FCAE@33958,4HBRJ@91061,COG1070@1,COG1070@2 NA|NA|NA G Xylulose kinase KIAJIJGH_00240 334390.LAF_1135 1.7e-215 755.0 Lactobacillaceae Bacteria 1UYZ1@1239,3F64G@33958,4IFB2@91061,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase family KIAJIJGH_00241 334390.LAF_1136 3.9e-195 687.2 Lactobacillaceae lplA 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 Bacteria 1TQ5U@1239,3F4UZ@33958,4H9P6@91061,COG0095@1,COG0095@2 NA|NA|NA H Lipoate-protein ligase KIAJIJGH_00242 334390.LAF_1137 3.1e-259 900.6 Lactobacillaceae lpdA GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006103,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006520,GO:0006544,GO:0006546,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015036,GO:0016054,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017144,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019464,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0036211,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045250,GO:0045252,GO:0045254,GO:0046390,GO:0046395,GO:0046483,GO:0046496,GO:0046872,GO:0046914,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0065007,GO:0065008,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0097159,GO:0106077,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 iAPECO1_1312.APECO1_1869,iEcolC_1368.EcolC_3543,iPC815.YPO3417,iSFV_1184.SFV_0107,iUMN146_1321.UM146_23385 Bacteria 1TP1W@1239,3F426@33958,4HB3K@91061,COG1249@1,COG1249@2 NA|NA|NA C Dehydrogenase KIAJIJGH_00243 334390.LAF_1138 4.5e-204 717.2 Lactobacillaceae pdhC 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1TR5N@1239,3F3RR@33958,4HA7A@91061,COG0508@1,COG0508@2 NA|NA|NA C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex KIAJIJGH_00244 334390.LAF_1139 1.7e-179 635.2 Lactobacillaceae pdhB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944,GO:0140030,GO:0140032 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2496c,iYO844.BSU14590 Bacteria 1TP3J@1239,3F4RV@33958,4HA4H@91061,COG0022@1,COG0022@2 NA|NA|NA C Transketolase, C-terminal domain protein KIAJIJGH_00245 334390.LAF_1140 1.8e-182 645.2 Lactobacillaceae pdhA 1.2.4.1,1.2.4.4 ko:K00161,ko:K00166 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00036,M00307 R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 Bacteria 1TQDG@1239,3F3JK@33958,4H9PQ@91061,COG1071@1,COG1071@2 NA|NA|NA C Dehydrogenase E1 component KIAJIJGH_00246 334390.LAF_1141 1e-30 138.7 Lactobacillaceae yphJ 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 R03470 RC00938 ko00000,ko00001,ko01000 Bacteria 1VWSB@1239,3F736@33958,4HJ1V@91061,COG0599@1,COG0599@2 NA|NA|NA S decarboxylase KIAJIJGH_00247 334390.LAF_1142 1.8e-53 214.9 Lactobacillaceae azlD Bacteria 1V9YS@1239,3F8HI@33958,4HJID@91061,COG1687@1,COG1687@2 NA|NA|NA E Branched-chain amino acid transport KIAJIJGH_00248 334390.LAF_1143 6.1e-123 446.8 Lactobacillaceae azlC Bacteria 1TP8P@1239,3F5PP@33958,4HE6G@91061,COG1296@1,COG1296@2 NA|NA|NA E azaleucine resistance protein AzlC KIAJIJGH_00249 334390.LAF_1144 5.5e-286 989.6 Lactobacillaceae thrC 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS16355,iIT341.HP0098 Bacteria 1TPR0@1239,3F3UF@33958,4H9R7@91061,COG0498@1,COG0498@2 NA|NA|NA E Threonine synthase KIAJIJGH_00250 334390.LAF_1145 3.9e-232 810.4 Lactobacillaceae hom GO:0003674,GO:0003824,GO:0004412,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3,2.7.2.4 ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1294,iSB619.SA_RS06610 Bacteria 1TQ2H@1239,3F5BM@33958,4HBAP@91061,COG0460@1,COG0460@2 NA|NA|NA E homoserine dehydrogenase KIAJIJGH_00251 334390.LAF_1146 1.2e-155 555.8 Lactobacillaceae thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_0003,iJN678.thrB,iLJ478.TM0545,iSB619.SA_RS06620 Bacteria 1TRWS@1239,3F44T@33958,4HCQN@91061,COG0083@1,COG0083@2 NA|NA|NA F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate KIAJIJGH_00252 334390.LAF_1147 3.5e-99 367.5 Lactobacillaceae Bacteria 1VZ11@1239,3FBE8@33958,4HH5T@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain KIAJIJGH_00253 334390.LAF_1148 1.5e-112 412.1 Lactobacillaceae ylbE Bacteria 1TQFS@1239,3F521@33958,4HDA2@91061,COG0702@1,COG0702@2 NA|NA|NA GM NAD(P)H-binding KIAJIJGH_00254 334390.LAF_1149 2.8e-117 427.9 Lactobacillaceae ypgQ ko:K06950 ko00000 Bacteria 1V7IZ@1239,3F3PN@33958,4HIVB@91061,COG1418@1,COG1418@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. KIAJIJGH_00255 334390.LAF_1150 4.8e-134 483.8 Bacilli ko:K09861 ko00000 Bacteria 1V5Z7@1239,4HM7S@91061,COG3022@1,COG3022@2 NA|NA|NA S Belongs to the UPF0246 family KIAJIJGH_00256 334390.LAF_1151 1.3e-97 362.5 Lactobacillaceae Bacteria 1U6MD@1239,29PI5@1,30AGA@2,3F85A@33958,4IGE8@91061 NA|NA|NA KIAJIJGH_00257 334390.LAF_1152 3.2e-161 574.3 Lactobacillaceae degV Bacteria 1TRM7@1239,3F40W@33958,4HBIR@91061,COG1307@1,COG1307@2 NA|NA|NA S EDD domain protein, DegV family KIAJIJGH_00258 334390.LAF_1153 0.0 1115.5 Lactobacillaceae FbpA ko:K12341 ko03070,map03070 ko00000,ko00001,ko02044 1.B.40.1.1 Bacteria 1TQ8A@1239,3F3PS@33958,4H9UF@91061,COG1293@1,COG1293@2 NA|NA|NA K Fibronectin-binding protein KIAJIJGH_00259 1071400.LBUCD034_0057 3.5e-60 238.4 Lactobacillaceae kguE 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1VA9Q@1239,3F651@33958,4HJ2W@91061,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase domain protein TIM barrel KIAJIJGH_00260 1071400.LBUCD034_0056 4.8e-158 564.3 Lactobacillaceae Bacteria 1TQVU@1239,3FBYW@33958,4HE97@91061,COG3069@1,COG3069@2 NA|NA|NA C C4-dicarboxylate transmembrane transporter activity KIAJIJGH_00261 334390.LAF_1763 3.7e-31 140.2 Lactobacillaceae ko:K03719 ko00000,ko03000,ko03036 Bacteria 1V3MI@1239,3F6FN@33958,4HJUY@91061,COG1522@1,COG1522@2 NA|NA|NA K AsnC family KIAJIJGH_00265 334390.LAF_0360 1.3e-102 379.0 Lactobacillaceae clpP GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 1TQ91@1239,3F3M0@33958,4HA8J@91061,COG0740@1,COG0740@2 NA|NA|NA O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins KIAJIJGH_00266 334390.LAF_0359 2.5e-118 431.4 Lactobacillaceae tenA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.2 ko:K03707 ko00730,ko01100,map00730,map01100 R02133,R09993 RC00224,RC00652,RC02832 ko00000,ko00001,ko01000,ko03000 Bacteria 1V9SR@1239,3F606@33958,4HK9S@91061,COG0819@1,COG0819@2 NA|NA|NA K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway KIAJIJGH_00267 334390.LAF_0358 1.9e-167 595.1 Lactobacillaceae whiA GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944 ko:K09762 ko00000 Bacteria 1TP2X@1239,3F4AB@33958,4HB4H@91061,COG1481@1,COG1481@2 NA|NA|NA K May be required for sporulation KIAJIJGH_00268 334390.LAF_0357 1.7e-187 661.8 Lactobacillaceae ybhK Bacteria 1TPNV@1239,3F4D5@33958,4HA0Z@91061,COG0391@1,COG0391@2 NA|NA|NA S Required for morphogenesis under gluconeogenic growth conditions KIAJIJGH_00269 334390.LAF_0356 3.3e-158 564.3 Lactobacillaceae rapZ GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 ko:K06958 ko00000,ko03019 Bacteria 1TPS4@1239,3F4NY@33958,4H9KM@91061,COG1660@1,COG1660@2 NA|NA|NA S Displays ATPase and GTPase activities KIAJIJGH_00270 334390.LAF_0355 7.6e-205 719.5 Lactobacillaceae Bacteria 1U7VC@1239,2BK8E@1,32ENE@2,3FA80@33958,4IHSS@91061 NA|NA|NA KIAJIJGH_00271 334390.LAF_0354 0.0 1895.9 Lactobacillaceae uvrA ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TPIJ@1239,3F4TZ@33958,4HAW9@91061,COG0178@1,COG0178@2 NA|NA|NA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate KIAJIJGH_00272 334390.LAF_0353 0.0 1291.9 Lactobacillaceae uvrB ko:K03702,ko:K08999 ko03420,map03420 ko00000,ko00001,ko03400 Bacteria 1TPKB@1239,3F3XM@33958,4HB81@91061,COG0556@1,COG0556@2 NA|NA|NA L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage KIAJIJGH_00274 334390.LAF_0351 6.8e-113 413.3 Lactobacillaceae yfbR ko:K07023 ko00000 Bacteria 1TSDU@1239,3F4RZ@33958,4HA8H@91061,COG1896@1,COG1896@2 NA|NA|NA S HD containing hydrolase-like enzyme KIAJIJGH_00275 334390.LAF_0350 0.0 1141.3 Lactobacillaceae pgm GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 5.4.2.2,5.4.2.8 ko:K01835,ko:K01840 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114,M00549 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP2N@1239,3F457@33958,4HADU@91061,COG1109@1,COG1109@2 NA|NA|NA G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain KIAJIJGH_00276 334390.LAF_0349 2.8e-137 494.6 Lactobacillaceae cof Bacteria 1V9NB@1239,3F6H9@33958,4HJAD@91061,COG0561@1,COG0561@2 NA|NA|NA S haloacid dehalogenase-like hydrolase KIAJIJGH_00277 334390.LAF_0348 1.6e-171 608.6 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1UXY2@1239,3F4M2@33958,4HD1S@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily KIAJIJGH_00278 334390.LAF_0347 3.8e-198 697.2 Lactobacillaceae ilvE 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TQQI@1239,3F4BD@33958,4HASX@91061,COG0115@1,COG0115@2 NA|NA|NA E Branched-chain amino acid aminotransferase KIAJIJGH_00279 334390.LAF_0346 2.6e-169 601.3 Lactobacillaceae cysK GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP30@1239,3F4VD@33958,4HAMU@91061,COG0031@1,COG0031@2 NA|NA|NA E Belongs to the cysteine synthase cystathionine beta- synthase family KIAJIJGH_00280 334390.LAF_0345 6e-154 550.1 Lactobacillaceae metAA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0008899,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS11970 Bacteria 1TQVR@1239,3F5CA@33958,4H9W4@91061,COG1897@1,COG1897@2 NA|NA|NA E Transfers an acetyl group from acetyl-CoA to KIAJIJGH_00281 575594.ACOH01000010_gene1697 1.7e-131 475.7 Lactobacillaceae trxB 1.8.1.9 ko:K00384 ko00450,map00450 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 Bacteria 1TNZS@1239,3F411@33958,4HA4N@91061,COG0492@1,COG0492@2 NA|NA|NA C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family KIAJIJGH_00282 334390.LAF_0344 1.5e-76 292.0 Lactobacillaceae yphH Bacteria 1V3TP@1239,3FBIH@33958,4HWR6@91061,COG1917@1,COG1917@2 NA|NA|NA S Cupin domain KIAJIJGH_00283 334390.LAF_0343 5.8e-188 663.3 Lactobacillaceae panE 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSZ1@1239,3F455@33958,4HB4T@91061,COG1893@1,COG1893@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid KIAJIJGH_00284 334390.LAF_0342 3.2e-225 787.3 Lactobacillaceae mtnE 2.6.1.83 ko:K08969,ko:K10206 ko00270,ko00300,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map01100,map01110,map01130,map01230 M00034,M00527 R07396,R07613 RC00006,RC01847 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TQD6@1239,3F4TW@33958,4HAHQ@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase KIAJIJGH_00285 334390.LAF_0341 7.5e-146 523.1 Lactobacillaceae mtnU 3.5.1.3 ko:K11206,ko:K13566 ko00250,map00250 R00269,R00348 RC00010 ko00000,ko00001,ko01000 Bacteria 1TQDK@1239,3F4ND@33958,4HC44@91061,COG0388@1,COG0388@2 NA|NA|NA S Carbon-nitrogen hydrolase KIAJIJGH_00286 334390.LAF_0340 2.1e-171 608.2 Lactobacillaceae galU 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ24@1239,3F45A@33958,4HATY@91061,COG1210@1,COG1210@2 NA|NA|NA M UTP-glucose-1-phosphate uridylyltransferase KIAJIJGH_00287 334390.LAF_0339 5.3e-184 650.2 Lactobacillaceae gpsA GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 R00842,R00844 RC00029 ko00000,ko00001,ko01000 Bacteria 1TQ5P@1239,3F4C8@33958,4HAXW@91061,COG0240@1,COG0240@2 NA|NA|NA I Glycerol-3-phosphate dehydrogenase KIAJIJGH_00288 334390.LAF_0338 4.7e-162 577.0 Lactobacillaceae lgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009898,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 ko:K03438,ko:K13292 ko00000,ko01000,ko03009 Bacteria 1TPAK@1239,3F42N@33958,4HAT0@91061,COG0682@1,COG0682@2 NA|NA|NA M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins KIAJIJGH_00289 334390.LAF_0337 9.2e-178 629.4 Lactobacillaceae hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 ko:K06023 ko00000,ko01000 Bacteria 1TP5Z@1239,3F3Z3@33958,4HAXR@91061,COG1493@1,COG1493@2 NA|NA|NA F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion KIAJIJGH_00290 334390.LAF_0336 1.2e-47 195.7 Lactobacillaceae yvlD ko:K08972 ko00000 Bacteria 1VF4I@1239,3F7IN@33958,4HNXP@91061,COG1950@1,COG1950@2 NA|NA|NA S Mycobacterial 4 TMS phage holin, superfamily IV KIAJIJGH_00291 334390.LAF_0335 4.1e-53 213.8 Lactobacillaceae ko:K03973 ko00000,ko02048,ko03000 Bacteria 1VKBQ@1239,3F7XD@33958,4HQZ8@91061,COG1983@1,COG1983@2 NA|NA|NA KT PspC domain protein KIAJIJGH_00292 334390.LAF_0334 1.3e-201 708.8 Lactobacillaceae prfB GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02836 ko00000,ko03012 Bacteria 1TPSB@1239,3F3SN@33958,4H9N2@91061,COG1186@1,COG1186@2 NA|NA|NA J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA KIAJIJGH_00293 334390.LAF_0333 0.0 1550.0 Lactobacillaceae secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 1TPEY@1239,3F4DH@33958,4HA22@91061,COG0653@1,COG0653@2 NA|NA|NA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane KIAJIJGH_00294 334390.LAF_0332 6.5e-96 356.7 Lactobacillaceae hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 ko:K05808 ko00000,ko03009 Bacteria 1V1D5@1239,3F40M@33958,4HFX9@91061,COG1544@1,COG1544@2 NA|NA|NA J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase KIAJIJGH_00295 334390.LAF_0331 1.2e-128 465.7 Lactobacillaceae comFC ko:K02242 M00429 ko00000,ko00002,ko02044 Bacteria 1V73S@1239,3F714@33958,4HJ6R@91061,COG1040@1,COG1040@2 NA|NA|NA S Competence protein KIAJIJGH_00296 334390.LAF_0330 6.5e-251 872.8 Lactobacillaceae comFA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K02240 M00429 ko00000,ko00002,ko02044 3.A.11.1 Bacteria 1TPZE@1239,3F3TQ@33958,4HB00@91061,COG4098@1,COG4098@2 NA|NA|NA L Helicase C-terminal domain protein KIAJIJGH_00297 334390.LAF_0329 9e-113 412.9 Lactobacillaceae yvyE 3.4.13.9 ko:K01271 ko00000,ko01000,ko01002 Bacteria 1V6MQ@1239,3F3SQ@33958,4HBIT@91061,COG1739@1,COG1739@2 NA|NA|NA S YigZ family KIAJIJGH_00298 334390.LAF_0328 6.4e-38 162.9 Lactobacillaceae Bacteria 1U79N@1239,29PH0@1,30AYE@2,3F95S@33958,4IH4I@91061 NA|NA|NA KIAJIJGH_00299 334390.LAF_0327 0.0 1169.1 Lactobacillaceae ydaO GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 Bacteria 1TQE1@1239,3F44Y@33958,4HAZH@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid KIAJIJGH_00300 334390.LAF_0326 1.4e-290 1005.0 Lactobacillaceae groL GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065 ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Bacteria 1TP1T@1239,3F3MM@33958,4HA38@91061,COG0459@1,COG0459@2 NA|NA|NA O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions KIAJIJGH_00301 334390.LAF_0325 4.3e-43 180.3 Lactobacillaceae groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0032991,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:0101031,GO:1903506,GO:1990220,GO:2000112,GO:2001141 ko:K04078 ko00000,ko03029,ko03110 Bacteria 1V9ZM@1239,3F7CZ@33958,4HKEK@91061,COG0234@1,COG0234@2 NA|NA|NA O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter KIAJIJGH_00302 334390.LAF_0324 4.4e-115 420.6 Lactobacillaceae rex ko:K01926 ko00000,ko03000 Bacteria 1TSMR@1239,3F40G@33958,4HB7Q@91061,COG2344@1,COG2344@2 NA|NA|NA K Modulates transcription in response to changes in cellular NADH NAD( ) redox state KIAJIJGH_00303 334390.LAF_0323 0.0 1195.6 Lactobacillaceae uup ko:K06158 ko00000,ko03012 Bacteria 1TPAX@1239,3F3QI@33958,4HBVV@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter, ATP-binding protein KIAJIJGH_00304 334390.LAF_0322 5.6e-175 620.2 Lactobacillaceae birA GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 ko:K03524,ko:K04096 ko00780,ko01100,map00780,map01100 R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 Bacteria 1TQCU@1239,3F5HY@33958,4HB60@91061,COG0340@1,COG0340@2,COG1654@1,COG1654@2 NA|NA|NA H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor KIAJIJGH_00305 334390.LAF_0321 3.7e-91 340.9 Lactobacillaceae bioY GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 ko:K03523 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 Bacteria 1VAAD@1239,3F6YG@33958,4HI8T@91061,COG1268@1,COG1268@2 NA|NA|NA S BioY family KIAJIJGH_00306 334390.LAF_0320 1.5e-135 488.8 Lactobacillaceae fabI GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPVD@1239,3F4AQ@33958,4H9YN@91061,COG0623@1,COG0623@2 NA|NA|NA I Enoyl- acyl-carrier-protein reductase NADH KIAJIJGH_00307 334390.LAF_0319 1e-139 502.7 Lactobacillaceae accA 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHNS@1239,3F496@33958,4HA4C@91061,COG0825@1,COG0825@2 NA|NA|NA I alpha subunit KIAJIJGH_00308 334390.LAF_0318 1.5e-160 572.0 Lactobacillaceae accD 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP4U@1239,3F3T6@33958,4HAI7@91061,COG0777@1,COG0777@2 NA|NA|NA I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA KIAJIJGH_00309 334390.LAF_0317 7.1e-264 916.0 Lactobacillaceae accC GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 iSF_1195.SF3294 Bacteria 1TP16@1239,3F3PT@33958,4HARK@91061,COG0439@1,COG0439@2 NA|NA|NA I Acetyl-CoA carboxylase biotin carboxylase subunit KIAJIJGH_00310 334390.LAF_0316 5e-75 287.0 Lactobacillaceae fabZ 3.5.1.108,4.2.1.59 ko:K02372,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212 M00060,M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 Bacteria 1V6EX@1239,3F5EE@33958,4HGX1@91061,COG0764@1,COG0764@2 NA|NA|NA I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs KIAJIJGH_00311 334390.LAF_0315 1.6e-63 248.8 Lactobacillaceae accB 2.3.1.12,4.1.1.3 ko:K00627,ko:K01571,ko:K02160 ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00307,M00376 R00209,R00217,R00742,R02569 RC00004,RC00040,RC00367,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000,ko02000 3.B.1.1.1 Bacteria 1VAB7@1239,3F7M1@33958,4HKCS@91061,COG0511@1,COG0511@2 NA|NA|NA I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA KIAJIJGH_00312 334390.LAF_0314 1.7e-229 801.6 Lactobacillaceae fabF 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPA7@1239,3F51H@33958,4H9SD@91061,COG0304@1,COG0304@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP KIAJIJGH_00313 334390.LAF_0313 2.7e-129 468.0 Lactobacillaceae Bacteria 1TP76@1239,3F4RI@33958,4HAA6@91061,COG1028@1,COG1028@2 NA|NA|NA IQ reductase KIAJIJGH_00314 334390.LAF_0312 1.1e-172 612.5 Lactobacillaceae fabD 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPB7@1239,3F3W9@33958,4HBCU@91061,COG0331@1,COG0331@2 NA|NA|NA I Malonyl CoA-acyl carrier protein transacylase KIAJIJGH_00315 334390.LAF_0311 4.2e-34 150.2 Lactobacillaceae acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 ko:K02078 ko00000,ko00001 Bacteria 1VGIY@1239,3F7ZJ@33958,4HP0V@91061,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis KIAJIJGH_00316 334390.LAF_0310 1.8e-173 615.1 Lactobacillaceae fabH 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TP0K@1239,3F3XP@33958,4HATK@91061,COG0332@1,COG0332@2 NA|NA|NA I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids KIAJIJGH_00317 334390.LAF_0309 2.3e-75 288.1 Lactobacillaceae marR Bacteria 1VDIT@1239,3F6SX@33958,4HNFP@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator, MarR family KIAJIJGH_00318 334390.LAF_0308 1.3e-75 288.9 Lactobacillaceae fabZ 3.5.1.108,4.2.1.59 ko:K02372,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212 M00060,M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 Bacteria 1V6RB@1239,3FCD4@33958,4HJS6@91061,COG0764@1,COG0764@2 NA|NA|NA I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs KIAJIJGH_00320 334390.LAF_0306 1.2e-194 685.6 Lactobacillaceae tsaD GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 R10648 RC00070,RC00416 ko00000,ko00001,ko00002,ko01000,ko02044,ko03016 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 Bacteria 1TQDR@1239,3F4AX@33958,4HANB@91061,COG0533@1,COG0533@2 NA|NA|NA J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction KIAJIJGH_00321 334390.LAF_0305 5.1e-110 403.7 Lactobacillaceae rimI 2.3.1.128 ko:K03789 ko00000,ko01000,ko03009 Bacteria 1V6KU@1239,3F522@33958,4HIKU@91061,COG0454@1,COG0456@2 NA|NA|NA K Ribosomal-protein-alanine acetyltransferase KIAJIJGH_00322 334390.LAF_0304 2.2e-131 474.9 Lactobacillaceae yeaZ GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K14742 R10648 RC00070,RC00416 ko00000,ko01000,ko03016 Bacteria 1V4YX@1239,3F3WV@33958,4HHD7@91061,COG1214@1,COG1214@2 NA|NA|NA O Universal bacterial protein YeaZ KIAJIJGH_00323 334390.LAF_0303 7.6e-216 756.1 Lactobacillaceae arcT 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 Bacteria 1TQPD@1239,3F3PZ@33958,4HE7P@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase KIAJIJGH_00324 334390.LAF_0302 2.7e-221 774.2 Lactobacillaceae yxjG 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPDQ@1239,3F49P@33958,4HADW@91061,COG0620@1,COG0620@2 NA|NA|NA E methionine synthase, vitamin-B12 independent KIAJIJGH_00325 334390.LAF_0301 2.7e-258 897.5 Lactobacillaceae ko:K03758 ko00000,ko02000 2.A.3.2 Bacteria 1TSSB@1239,3F3P5@33958,4HA92@91061,COG0531@1,COG0531@2 NA|NA|NA E Arginine ornithine antiporter KIAJIJGH_00326 334390.LAF_0300 8.2e-240 835.9 Lactobacillaceae arcA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0008218,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016810,GO:0016813,GO:0016990,GO:0018101,GO:0018193,GO:0018195,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.3.6 ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 R00552 RC00177 ko00000,ko00001,ko01000 Bacteria 1TQWS@1239,3F4VJ@33958,4HCMG@91061,COG2235@1,COG2235@2 NA|NA|NA E Arginine KIAJIJGH_00327 334390.LAF_0299 1.4e-167 595.5 Lactobacillaceae arcC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 R00150,R01395 RC00002,RC00043,RC02803,RC02804 ko00000,ko00001,ko01000 Bacteria 1TP9H@1239,3F3T4@33958,4H9QD@91061,COG0549@1,COG0549@2 NA|NA|NA E Belongs to the carbamate kinase family KIAJIJGH_00328 334390.LAF_0298 6e-188 663.3 Lactobacillaceae argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0033554,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 iAF1260.b0273,iECDH10B_1368.ECDH10B_0261,iECS88_1305.ECS88_4841,iHN637.CLJU_RS12430,iJO1366.b0273,iJR904.b0273,iY75_1357.Y75_RS01410 Bacteria 1TPF2@1239,3F48K@33958,4H9X8@91061,COG0078@1,COG0078@2 NA|NA|NA E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline KIAJIJGH_00329 334390.LAF_0297 6.9e-145 520.0 Lactobacillaceae ko:K03413,ko:K07719 ko02020,ko02030,map02020,map02030 M00506,M00518 ko00000,ko00001,ko00002,ko02022,ko02035 Bacteria 1UHR2@1239,3F61D@33958,4HIGR@91061,COG2197@1,COG2197@2 NA|NA|NA KT YcbB domain KIAJIJGH_00330 334390.LAF_0296 1.2e-191 675.6 Lactobacillaceae galE 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ7N@1239,3F3YF@33958,4H9U5@91061,COG1087@1,COG1087@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family KIAJIJGH_00331 334390.LAF_0295 8.2e-171 606.3 Lactobacillaceae ppx 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 1TS3I@1239,3F3SR@33958,4HAQS@91061,COG0248@1,COG0248@2 NA|NA|NA FP exopolyphosphatase KIAJIJGH_00332 334390.LAF_0294 0.0 1461.8 Lactobacillaceae ppk GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 iJN746.PP_5217 Bacteria 1TNZM@1239,3F3PE@33958,4HA88@91061,COG0855@1,COG0855@2 NA|NA|NA P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) KIAJIJGH_00333 334390.LAF_0293 1.6e-282 978.0 Lactobacillaceae ppx3 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 1VT8Q@1239,3F49N@33958,4HB84@91061,COG0248@1,COG0248@2 NA|NA|NA FP exopolyphosphatase KIAJIJGH_00334 334390.LAF_0292 7.3e-146 523.1 Lactobacillaceae fat 3.1.2.21 ko:K01071 ko00061,ko01100,map00061,map01100 R04014,R08157,R08158 RC00014,RC00039 ko00000,ko00001,ko01000,ko01004 Bacteria 1V3RB@1239,3F41B@33958,4HHJ4@91061,COG3884@1,COG3884@2 NA|NA|NA I Acyl-ACP thioesterase KIAJIJGH_00335 334390.LAF_0291 2.7e-157 561.2 Lactobacillaceae rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 ko:K07056 ko00000,ko01000,ko03009 Bacteria 1TP6U@1239,3F4AI@33958,4HAH8@91061,COG0313@1,COG0313@2 NA|NA|NA H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA KIAJIJGH_00336 334390.LAF_0290 1.5e-55 221.9 Lactobacillaceae yabA GO:0003674,GO:0005488,GO:0005515,GO:0042802 Bacteria 1VA1F@1239,3F864@33958,4HKND@91061,COG4467@1,COG4467@2 NA|NA|NA L Involved in initiation control of chromosome replication KIAJIJGH_00337 334390.LAF_0289 1.4e-192 678.7 Lactobacillaceae holB 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TRVS@1239,3F50D@33958,4HA3T@91061,COG0470@1,COG0470@2 NA|NA|NA L DNA polymerase III KIAJIJGH_00338 334390.LAF_0288 4e-53 213.8 Lactobacillaceae yaaQ Bacteria 1V6NI@1239,3F6VW@33958,4HIHA@91061,COG3870@1,COG3870@2 NA|NA|NA S Cyclic-di-AMP receptor KIAJIJGH_00339 334390.LAF_0287 6e-117 426.8 Lactobacillaceae tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS02535 Bacteria 1V1HE@1239,3F4JR@33958,4HGWR@91061,COG0125@1,COG0125@2 NA|NA|NA F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis KIAJIJGH_00340 557436.Lreu_0329 2.4e-21 107.8 Lactobacillaceae Bacteria 1U6F9@1239,2DKQF@1,30ABA@2,3F7S7@33958,4IG70@91061 NA|NA|NA S Protein of unknown function (DUF2508) KIAJIJGH_00341 334390.LAF_0285 3e-110 404.4 Lactobacillaceae recR GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1TR87@1239,3F4JQ@33958,4HAZR@91061,COG0353@1,COG0353@2 NA|NA|NA L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO KIAJIJGH_00342 334390.LAF_0284 4.9e-40 170.2 Lactobacillaceae yaaK ko:K09747 ko00000 Bacteria 1VA1S@1239,3F7F3@33958,4HKH3@91061,COG0718@1,COG0718@2 NA|NA|NA S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection KIAJIJGH_00343 334390.LAF_0283 0.0 1088.2 Lactobacillaceae dnaX GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 ko:K02341,ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TPS9@1239,3F3P2@33958,4HAUE@91061,COG2812@1,COG2812@2 NA|NA|NA L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity KIAJIJGH_00345 334390.LAF_0282 6.3e-80 303.5 Lactobacillaceae tadA 3.5.4.33 ko:K11991 R10223 RC00477 ko00000,ko01000,ko03016 Bacteria 1V3HZ@1239,3F6IS@33958,4HH7S@91061,COG0590@1,COG0590@2 NA|NA|NA F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) KIAJIJGH_00346 334390.LAF_0281 2e-35 154.5 Lactobacillaceae nrdH GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009893,GO:0009987,GO:0016491,GO:0019222,GO:0019725,GO:0022900,GO:0042592,GO:0043085,GO:0044093,GO:0044237,GO:0045454,GO:0048518,GO:0050789,GO:0050790,GO:0050794,GO:0051341,GO:0051353,GO:0055114,GO:0065007,GO:0065008,GO:0065009 ko:K06191 ko00000 Bacteria 1VE2N@1239,3FBRA@33958,4HSRX@91061,COG0695@1,COG0695@2 NA|NA|NA O Glutaredoxin KIAJIJGH_00347 334390.LAF_0280 0.0 1451.4 Lactobacillaceae nrdE 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 iYO844.BSU17380 Bacteria 1TPFH@1239,3F3XG@33958,4H9X0@91061,COG0209@1,COG0209@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides KIAJIJGH_00348 334390.LAF_0279 7.3e-194 682.9 Lactobacillaceae nrdF 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1TQTH@1239,3F3P1@33958,4H9WX@91061,COG0208@1,COG0208@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides KIAJIJGH_00349 334390.LAF_0278 1.3e-246 858.6 Lactobacillaceae brnQ GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903785,GO:1903825,GO:1905039 ko:K03311 ko00000 2.A.26 Bacteria 1TQIS@1239,3F3KC@33958,4HAKA@91061,COG1114@1,COG1114@2 NA|NA|NA U Component of the transport system for branched-chain amino acids KIAJIJGH_00350 334390.LAF_0277 0.0 1709.1 Lactobacillaceae adhE 1.1.1.1,1.2.1.10 ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 Bacteria 1TPB4@1239,3F3RN@33958,4HAN8@91061,COG1012@1,COG1012@2,COG1454@1,COG1454@2 NA|NA|NA C belongs to the iron- containing alcohol dehydrogenase family KIAJIJGH_00351 334390.LAF_0276 0.0 1141.3 Lactobacillaceae cydD ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 3.A.1.129 Bacteria 1UHN5@1239,3F4PG@33958,4HAAB@91061,COG4987@1,COG4987@2 NA|NA|NA CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC KIAJIJGH_00352 334390.LAF_0275 0.0 1115.9 Lactobacillaceae cydD GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 3.A.1.129 Bacteria 1TQ1P@1239,3F451@33958,4HAN0@91061,COG4988@1,COG4988@2 NA|NA|NA CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD KIAJIJGH_00353 334390.LAF_0274 4.1e-176 624.0 Lactobacillaceae cydB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iECABU_c1320.ECABU_c10120,iLF82_1304.LF82_0101,iNRG857_1313.NRG857_04455,iPC815.YPO1118,iYO844.BSU38750,ic_1306.c1120 Bacteria 1TRYV@1239,3F40S@33958,4H9KF@91061,COG1294@1,COG1294@2 NA|NA|NA C Cytochrome d ubiquinol oxidase subunit II KIAJIJGH_00354 334390.LAF_0273 4.3e-272 943.3 Lactobacillaceae cydA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 iPC815.YPO1117,iSBO_1134.SBO_2253,iSFxv_1172.SFxv_0621,iS_1188.S0577,iSbBS512_1146.SbBS512_E2337 Bacteria 1TRH4@1239,3F4MJ@33958,4HA19@91061,COG1271@1,COG1271@2 NA|NA|NA C ubiquinol oxidase KIAJIJGH_00355 334390.LAF_0272 4.6e-53 213.8 Lactobacillaceae rplL ko:K02935 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6EI@1239,3F6YA@33958,4HIGQ@91061,COG0222@1,COG0222@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation KIAJIJGH_00356 334390.LAF_0271 8.4e-82 309.7 Lactobacillaceae rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02864,ko:K02935 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3JJ@1239,3F4S4@33958,4HH0N@91061,COG0244@1,COG0244@2 NA|NA|NA J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors KIAJIJGH_00357 334390.LAF_0270 4.6e-244 850.1 Lactobacillaceae steT GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ48@1239,3F3YJ@33958,4HBGT@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid KIAJIJGH_00358 334390.LAF_0269 1.3e-120 439.1 Lactobacillaceae rplA GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02863 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPTS@1239,3F3VQ@33958,4HAK4@91061,COG0081@1,COG0081@2 NA|NA|NA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release KIAJIJGH_00359 334390.LAF_0268 2.2e-51 208.0 Lactobacillaceae rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02867 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1BS@1239,3F64I@33958,4HFQ0@91061,COG0080@1,COG0080@2 NA|NA|NA J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors KIAJIJGH_00360 334390.LAF_0267 4.5e-97 360.5 Lactobacillaceae nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K02601 ko00000,ko03009,ko03021 Bacteria 1TR3P@1239,3F55W@33958,4HAJA@91061,COG0250@1,COG0250@2 NA|NA|NA K Participates in transcription elongation, termination and antitermination KIAJIJGH_00361 334390.LAF_0266 2.4e-23 114.0 Firmicutes secE GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1VK48@1239,COG0690@1,COG0690@2 NA|NA|NA U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation KIAJIJGH_00362 334390.LAF_0265 3.2e-21 106.7 Lactobacillaceae rpmG ko:K02913 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VFTQ@1239,3F83F@33958,4HR5Q@91061,COG0267@1,COG0267@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL33 family KIAJIJGH_00363 334390.LAF_0264 2.4e-104 384.8 Bacilli sigH ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Bacteria 1TP55@1239,4HAHR@91061,COG1595@1,COG1595@2 NA|NA|NA K Belongs to the sigma-70 factor family KIAJIJGH_00364 334390.LAF_0263 2e-135 488.4 Lactobacillaceae rlmB GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218,ko:K03437,ko:K12952 ko00000,ko01000,ko03009,ko03016 3.A.3.23 Bacteria 1TP9G@1239,3F3TD@33958,4HBBI@91061,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family KIAJIJGH_00365 334390.LAF_0262 1.6e-70 271.9 Lactobacillaceae mrnC GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 ko:K11145 ko00000,ko01000,ko03009 Bacteria 1VA5V@1239,3F6HS@33958,4HIM3@91061,COG1939@1,COG1939@2 NA|NA|NA J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) KIAJIJGH_00366 334390.LAF_0261 1e-270 938.7 Lactobacillaceae cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16,6.3.1.13 ko:K01883,ko:K15526 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iECUMN_1333.ECUMN_0566,iJN746.PP_2905 Bacteria 1TP9D@1239,3F4K7@33958,4HA6D@91061,COG0215@1,COG0215@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family KIAJIJGH_00367 334390.LAF_0260 1.1e-98 365.9 Lactobacillaceae ywlG Bacteria 1V3H0@1239,3F66D@33958,4HH6F@91061,COG4475@1,COG4475@2 NA|NA|NA S Belongs to the UPF0340 family KIAJIJGH_00368 334390.LAF_0259 9.6e-291 1005.4 Lactobacillaceae gltX GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009986,GO:0030246,GO:0030247,GO:0044424,GO:0044464,GO:2001065 6.1.1.17,6.1.1.24 ko:K01885,ko:K09698 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 iSB619.SA_RS02860 Bacteria 1TPJC@1239,3F3PR@33958,4HAKH@91061,COG0008@1,COG0008@2 NA|NA|NA J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) KIAJIJGH_00369 334390.LAF_0258 7.2e-206 723.0 Lactobacillaceae yacL GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 Bacteria 1TP0P@1239,3F46T@33958,4H9NQ@91061,COG4956@1,COG4956@2 NA|NA|NA S domain protein KIAJIJGH_00370 334390.LAF_0257 5.6e-253 879.8 Lactobacillaceae radA ko:K04485 ko00000,ko03400 Bacteria 1TQ7Y@1239,3F3W8@33958,4H9YC@91061,COG1066@1,COG1066@2 NA|NA|NA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function KIAJIJGH_00371 334390.LAF_0256 1.4e-98 365.5 Lactobacillaceae dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23,4.1.1.36,6.3.2.5 ko:K01520,ko:K13038 ko00240,ko00770,ko00983,ko01100,map00240,map00770,map00983,map01100 M00053,M00120 R02100,R03269,R04231,R11896 RC00002,RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1V6HX@1239,3F65D@33958,4HIZ3@91061,COG0756@1,COG0756@2 NA|NA|NA F dUTP diphosphatase KIAJIJGH_00372 334390.LAF_0255 4.2e-55 220.3 Bacteria HA62_12640 ko:K06975 ko00000 Bacteria COG2388@1,COG2388@2 NA|NA|NA S GCN5-related N-acetyl-transferase KIAJIJGH_00373 334390.LAF_0254 6.7e-122 443.4 Lactobacillaceae rpiA GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,5.3.1.6 ko:K00851,ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056,R01737 RC00002,RC00017,RC00434 ko00000,ko00001,ko00002,ko01000 Bacteria 1V1DB@1239,3F5MX@33958,4IF4W@91061,COG0120@1,COG0120@2 NA|NA|NA G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate KIAJIJGH_00374 334390.LAF_0253 1.1e-94 352.8 Lactobacillaceae maa 2.3.1.18,2.3.1.79 ko:K00633,ko:K00661 ko00000,ko01000 Bacteria 1V06U@1239,3FBEW@33958,4IPZB@91061,COG0110@1,COG0110@2 NA|NA|NA S Transferase hexapeptide repeat KIAJIJGH_00375 334390.LAF_0252 4e-264 916.8 Lactobacillaceae pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 ko00000,ko01000,ko01002 Bacteria 1TRJN@1239,3F49B@33958,4HBZ9@91061,COG3579@1,COG3579@2 NA|NA|NA E Peptidase C1-like family KIAJIJGH_00376 334390.LAF_0251 1.3e-167 595.5 Lactobacillaceae Bacteria 1VSAN@1239,3F60S@33958,4HEXJ@91061,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold KIAJIJGH_00377 334390.LAF_0250 1.4e-127 462.2 Lactobacillaceae gpmA GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1V2UT@1239,3FB95@33958,4HGRK@91061,COG0588@1,COG0588@2 NA|NA|NA G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate KIAJIJGH_00378 334390.LAF_0249 3.6e-166 590.9 Lactobacillaceae mleP2 ko:K07088 ko00000 Bacteria 1UY4N@1239,3F3S0@33958,4HDX5@91061,COG0679@1,COG0679@2 NA|NA|NA S Sodium Bile acid symporter family KIAJIJGH_00379 334390.LAF_0248 4e-189 667.2 Lactobacillaceae lacM 3.2.1.23,3.2.1.35,3.2.1.51,3.2.1.97 ko:K01190,ko:K01197,ko:K01206,ko:K17624 ko00052,ko00511,ko00531,ko00600,ko01100,map00052,map00511,map00531,map00600,map01100 M00076,M00077 R01105,R01678,R03355,R04783,R06114,R07824,R07825,R10905 RC00049,RC00452 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042,ko04147 GH101,GH29 Bacteria 1TRVA@1239,3F51Z@33958,4HFMH@91061,COG3250@1,COG3250@2 NA|NA|NA G beta-galactosidase KIAJIJGH_00380 334390.LAF_0247 0.0 1325.5 Lactobacillaceae lacL 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 Bacteria 1TPDC@1239,3F4EI@33958,4HANW@91061,COG3250@1,COG3250@2 NA|NA|NA G Belongs to the glycosyl hydrolase 2 family KIAJIJGH_00382 334390.LAF_0246 8.1e-84 316.2 Lactobacillaceae ydcK ko:K03095 ko00000 Bacteria 1V6NU@1239,3F703@33958,4HIHY@91061,COG3091@1,COG3091@2 NA|NA|NA S Belongs to the SprT family KIAJIJGH_00383 334390.LAF_0245 0.0 1406.0 Lactobacillaceae yhgF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 ko:K06959 ko00000 Bacteria 1TPFE@1239,3F415@33958,4HAGY@91061,COG2183@1,COG2183@2 NA|NA|NA K Tex-like protein N-terminal domain protein KIAJIJGH_00384 334390.LAF_0244 8.8e-153 546.2 Lactobacillaceae nadE GO:0003674,GO:0003824,GO:0003952,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0033554,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 iECSE_1348.ECSE_1910,iECW_1372.ECW_m1909,iEKO11_1354.EKO11_2035,iETEC_1333.ETEC_1772,iEcE24377_1341.EcE24377A_1961,iSFV_1184.SFV_1480,iSF_1195.SF1486,iSFxv_1172.SFxv_1676,iSSON_1240.SSON_1418,iS_1188.S1603,iWFL_1372.ECW_m1909 Bacteria 1TQ38@1239,3F43Z@33958,4HA2R@91061,COG0171@1,COG0171@2 NA|NA|NA F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source KIAJIJGH_00385 334390.LAF_0243 2.9e-284 983.8 Lactobacillaceae pncB GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 R01724 RC00033 ko00000,ko00001,ko01000 iYO844.BSU31750 Bacteria 1TPDW@1239,3F3K7@33958,4HAI4@91061,COG1488@1,COG1488@2 NA|NA|NA F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP KIAJIJGH_00386 334390.LAF_0242 1.4e-127 462.2 Lactobacillaceae gntR1 ko:K03710,ko:K11922 ko00000,ko03000 Bacteria 1UYBW@1239,3F4D0@33958,4HDDG@91061,COG2188@1,COG2188@2 NA|NA|NA K UbiC transcription regulator-associated domain protein KIAJIJGH_00387 334390.LAF_0241 4.3e-132 477.2 Lactobacillaceae racD 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 R00491 RC00302 ko00000,ko00001,ko01000 Bacteria 1V28U@1239,3FBJU@33958,4IQX8@91061,COG1794@1,COG1794@2 NA|NA|NA M Belongs to the aspartate glutamate racemases family KIAJIJGH_00388 334390.LAF_0240 9.6e-115 419.5 Lactobacillaceae Bacteria 1U5V7@1239,29NYS@1,309WV@2,3F6J8@33958,4IFIU@91061 NA|NA|NA KIAJIJGH_00391 334390.LAF_0239 1.7e-164 585.1 Lactobacillaceae yjjH Bacteria 1VHY9@1239,3F3SW@33958,4HPAR@91061,COG1409@1,COG1409@2 NA|NA|NA S Calcineurin-like phosphoesterase KIAJIJGH_00392 334390.LAF_0238 6.5e-255 886.3 Lactobacillaceae dtpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03305 ko00000 2.A.17 Bacteria 1TP81@1239,3F4WU@33958,4HAF2@91061,COG3104@1,COG3104@2 NA|NA|NA U amino acid peptide transporter KIAJIJGH_00393 334390.LAF_0237 1.2e-154 553.9 Lactobacillaceae Bacteria 1W39C@1239,3F754@33958,4I0DV@91061,COG1196@1,COG1196@2 NA|NA|NA D nuclear chromosome segregation KIAJIJGH_00395 334390.LAF_1779 2.4e-165 588.6 Lactobacillaceae Bacteria 1TRZH@1239,3F4XU@33958,4HE9W@91061,COG1002@1,COG1002@2 NA|NA|NA V Type II restriction enzyme, methylase subunits KIAJIJGH_00396 1316408.HSISM1_1338 6.2e-141 507.7 Bacilli Bacteria 1TRZH@1239,4HE9W@91061,COG1002@1,COG1002@2 NA|NA|NA V Type II restriction enzyme, methylase subunits KIAJIJGH_00398 405566.lhv_1986 4.6e-107 394.4 Lactobacillaceae Bacteria 1UIWH@1239,3F5HW@33958,4HI23@91061,COG0524@1,COG0524@2 NA|NA|NA G Belongs to the carbohydrate kinase PfkB family KIAJIJGH_00399 405566.lhv_1985 1.2e-109 402.5 Bacilli ko:K03457 ko00000 2.A.39 Bacteria 1TRAH@1239,4IRPE@91061,COG1457@1,COG1457@2 NA|NA|NA F Belongs to the purine-cytosine permease (2.A.39) family KIAJIJGH_00400 334390.LAF_1685 2.2e-170 604.7 Lactobacillaceae scrK 2.7.1.2,2.7.1.4 ko:K00845,ko:K00847 ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R00760,R00867,R01600,R01786,R03920 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQU4@1239,3F3K8@33958,4HA1C@91061,COG1940@1,COG1940@2 NA|NA|NA GK ROK family KIAJIJGH_00401 334390.LAF_1684 8.6e-235 819.3 Lactobacillaceae mepA ko:K18908 M00705 ko00000,ko00002,ko01504,ko02000 2.A.66.1.13 Bacteria 1TPFM@1239,3F3KX@33958,4HEHY@91061,COG0534@1,COG0534@2 NA|NA|NA V MATE efflux family protein KIAJIJGH_00402 334390.LAF_1683 7.4e-225 786.2 Lactobacillaceae amtB ko:K03320 ko00000,ko02000 1.A.11 Bacteria 1TQYG@1239,3F3X1@33958,4HBGK@91061,COG0004@1,COG0004@2 NA|NA|NA P ammonium transporter KIAJIJGH_00404 334390.LAF_1682 9.3e-133 479.6 Lactobacillaceae XK27_08845 ko:K05833 M00247 ko00000,ko00002,ko02000 Bacteria 1TPAN@1239,3F3NW@33958,4HCHC@91061,COG1101@1,COG1101@2 NA|NA|NA S ABC transporter, ATP-binding protein KIAJIJGH_00405 334390.LAF_1681 8.7e-138 496.5 Lactobacillaceae XK27_08840 ko:K05832 M00247 ko00000,ko00002,ko02000 Bacteria 1TPDJ@1239,3F40J@33958,4HBMY@91061,COG4120@1,COG4120@2 NA|NA|NA U Belongs to the binding-protein-dependent transport system permease family KIAJIJGH_00406 334390.LAF_1680 5.9e-180 636.7 Lactobacillaceae ABC-SBP ko:K01989,ko:K05832 M00247 ko00000,ko00002,ko02000 Bacteria 1TPB0@1239,3F462@33958,4HESK@91061,COG2984@1,COG2984@2 NA|NA|NA S ABC transporter KIAJIJGH_00407 334390.LAF_1679 3.4e-291 1006.9 Lactobacillaceae ko:K06158 ko00000,ko03012 Bacteria 1TPAX@1239,3F3QI@33958,4HBVV@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter, ATP-binding protein KIAJIJGH_00408 334390.LAF_1678 1.8e-206 724.9 Lactobacillaceae nrnB ko:K07097 ko00000 Bacteria 1TQPZ@1239,3F5R4@33958,4HCSM@91061,COG2404@1,COG2404@2 NA|NA|NA S DHHA1 domain KIAJIJGH_00410 334390.LAF_1676 5.1e-110 403.7 Lactobacillaceae Bacteria 1V4KP@1239,3F6PH@33958,4HIBF@91061,COG1376@1,COG1376@2 NA|NA|NA M ErfK YbiS YcfS YnhG KIAJIJGH_00411 334390.LAF_1675 1.4e-83 315.5 Lactobacillaceae nrdI GO:0000166,GO:0003674,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010181,GO:0019538,GO:0032553,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564 ko:K03647 ko00000 Bacteria 1V764@1239,3F4MF@33958,4HJVP@91061,COG1780@1,COG1780@2 NA|NA|NA F NrdI Flavodoxin like KIAJIJGH_00412 334390.LAF_1674 0.0 1441.4 Lactobacillaceae nrdE 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 iYO844.BSU17380 Bacteria 1TPFH@1239,3F3XG@33958,4H9X0@91061,COG0209@1,COG0209@2 NA|NA|NA F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides KIAJIJGH_00413 334390.LAF_1673 8.8e-170 602.8 Lactobacillaceae nrdF 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1TQTH@1239,3F5T7@33958,4H9WX@91061,COG0208@1,COG0208@2 NA|NA|NA F Ribonucleotide reductase, small chain KIAJIJGH_00414 334390.LAF_1672 1.2e-182 645.6 Lactobacillaceae 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1V0Y9@1239,3F63P@33958,4HC0F@91061,COG0208@1,COG0208@2 NA|NA|NA F Ribonucleotide reductase, small chain KIAJIJGH_00415 334390.LAF_1671 1.6e-276 958.4 Lactobacillaceae Bacteria 1VK4A@1239,2EM25@1,33ERN@2,3F53P@33958,4HRGD@91061 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2325) KIAJIJGH_00416 1423806.JCM15457_1839 1.3e-82 313.2 Lactobacillaceae cas2 GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0034641,GO:0043170,GO:0043570,GO:0043571,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.7.7.7 ko:K02342,ko:K09951 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03400 Bacteria 1V0CE@1239,3F4RJ@33958,4HVSS@91061,COG0847@1,COG0847@2 NA|NA|NA L CRISPR-associated protein (Cas_Cas2CT1978) KIAJIJGH_00417 748671.LCRIS_01208 3.2e-127 461.5 Lactobacillaceae cas1 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0008821,GO:0009987,GO:0016043,GO:0016787,GO:0016788,GO:0016888,GO:0016889,GO:0016893,GO:0016894,GO:0017108,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043570,GO:0043571,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048256,GO:0050896,GO:0051276,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K15342 ko00000,ko02048,ko03400 Bacteria 1TQ6F@1239,3F5DG@33958,4HU4Z@91061,COG1518@1,COG1518@2 NA|NA|NA L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette KIAJIJGH_00418 1423806.JCM15457_1837 3e-71 275.0 Lactobacillaceae casE ko:K19126 ko00000,ko02048 Bacteria 1V5I4@1239,2DKU6@1,30BEK@2,3F5AF@33958,4HWF1@91061 NA|NA|NA S CRISPR_assoc KIAJIJGH_00419 944562.HMPREF9102_1221 3.5e-65 255.0 Lactobacillaceae casD ko:K19125 ko00000,ko02048 Bacteria 1V2K8@1239,2DBXF@1,2ZBPB@2,3F68A@33958,4HX6U@91061 NA|NA|NA S CRISPR-associated protein (Cas_Cas5) KIAJIJGH_00420 748671.LCRIS_01211 9e-129 466.8 Lactobacillaceae casC GO:0002252,GO:0002376,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006950,GO:0006952,GO:0008150,GO:0009605,GO:0009607,GO:0009615,GO:0043207,GO:0050896,GO:0051607,GO:0051704,GO:0051707,GO:0071667,GO:0097159,GO:0098542,GO:1901363 ko:K19124 ko00000,ko02048 Bacteria 1TSM0@1239,3F3ZE@33958,4HTJZ@91061,COG1857@1,COG1857@2 NA|NA|NA L CT1975-like protein KIAJIJGH_00421 1423754.BALY01000020_gene761 5.4e-40 171.0 Lactobacillaceae casB ko:K19046 ko00000,ko02048 Bacteria 1VB3D@1239,2CK1Q@1,32UPV@2,3F6J5@33958,4HZ02@91061 NA|NA|NA S CRISPR-associated protein Cse2 (CRISPR_cse2) KIAJIJGH_00422 1423743.JCM14108_2083 3.8e-155 555.1 Lactobacillaceae casA ko:K07012,ko:K19123 ko00000,ko01000,ko02048 Bacteria 1TSVP@1239,3F55R@33958,4HUQ4@91061,COG1203@1,COG1203@2 NA|NA|NA L the current gene model (or a revised gene model) may contain a frame shift KIAJIJGH_00423 714313.LSA_2p00290 1.4e-223 782.7 Lactobacillaceae cas3 ko:K07012,ko:K19123 ko00000,ko01000,ko02048 Bacteria 1TQ9B@1239,3F4VV@33958,4HAH7@91061,COG1203@1,COG1203@2 NA|NA|NA L CRISPR-associated helicase cas3 KIAJIJGH_00424 1423743.JCM14108_3272 9.9e-39 165.6 Lactobacillaceae Bacteria 1TPPI@1239,3FB7D@33958,4HAKP@91061,COG1484@1,COG1484@2 NA|NA|NA L Bacterial dnaA protein KIAJIJGH_00425 1291743.LOSG293_220270 8.8e-49 199.9 Lactobacillaceae Bacteria 1TQN4@1239,3F5I0@33958,4HKTX@91061,COG4227@1,COG4227@2 NA|NA|NA L Psort location Cytoplasmic, score KIAJIJGH_00426 1033810.HLPCO_001077 1.3e-35 157.1 Bacteria Bacteria 28MDW@1,2ZARP@2 NA|NA|NA S Bacteriophage abortive infection AbiH KIAJIJGH_00427 1138822.PL11_10710 1.4e-34 151.8 Lactobacillaceae ko:K07493 ko00000 Bacteria 1TP4C@1239,3F4RA@33958,4HAXJ@91061,COG3328@1,COG3328@2 NA|NA|NA L Transposase KIAJIJGH_00428 334390.LAF_0972 5.9e-166 590.1 Lactobacillaceae adh 1.1.1.1,1.1.1.14 ko:K00001,ko:K00008 ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 M00014 R00623,R00754,R00875,R01896,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00085,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPIW@1239,3F5ST@33958,4HB2G@91061,COG1063@1,COG1063@2 NA|NA|NA C Zinc-binding dehydrogenase KIAJIJGH_00429 334390.LAF_1575 8.3e-51 207.2 Lactobacillaceae Bacteria 1V1QC@1239,3F65F@33958,4HH7E@91061,COG2963@1,COG2963@2 NA|NA|NA L Helix-turn-helix domain KIAJIJGH_00430 334390.LAF_0778 6.2e-85 320.9 Lactobacillaceae Bacteria 1TQEG@1239,3F43M@33958,4HD6M@91061,COG2801@1,COG2801@2 NA|NA|NA L hmm pf00665 KIAJIJGH_00431 334390.LAF_0935 4.7e-146 523.9 Lactobacillaceae Bacteria 1UR34@1239,3F4J5@33958,4HDF2@91061,COG1434@1,COG1434@2 NA|NA|NA S DUF218 domain KIAJIJGH_00432 334390.LAF_0936 2.8e-165 587.8 Lactobacillaceae 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 Bacteria 1TPM1@1239,3F3PW@33958,4HARE@91061,COG0656@1,COG0656@2 NA|NA|NA C Aldo keto reductase KIAJIJGH_00433 334390.LAF_0937 2.6e-80 304.7 Lactobacillaceae hmpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 Bacteria 1VBJP@1239,3FB41@33958,4HNRQ@91061,COG4720@1,COG4720@2 NA|NA|NA S ECF-type riboflavin transporter, S component KIAJIJGH_00434 334390.LAF_0938 8.3e-151 539.7 Lactobacillaceae pdxK 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TRCR@1239,3F3V7@33958,4HHME@91061,COG2240@1,COG2240@2 NA|NA|NA H Phosphomethylpyrimidine kinase KIAJIJGH_00435 334390.LAF_0939 2.6e-138 498.0 Lactobacillaceae icd GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 e_coli_core.b1136,iAF1260.b1136,iECDH1ME8569_1439.ECDH1ME8569_1071,iEcDH1_1363.EcDH1_2511,iJN746.PP_4011,iJO1366.b1136,iJR904.b1136,iY75_1357.Y75_RS05930,iYL1228.KPN_01144 Bacteria 1UHPE@1239,3F4G4@33958,4H9US@91061,COG0538@1,COG0538@2 NA|NA|NA C Isocitrate/isopropylmalate dehydrogenase KIAJIJGH_00436 1138822.PL11_07740 1.2e-25 122.5 Lactobacillaceae ywkB ko:K07088 ko00000 Bacteria 1VDS9@1239,3F5JF@33958,4HQT5@91061,COG0679@1,COG0679@2 NA|NA|NA S Membrane transport protein KIAJIJGH_00437 1138822.PL11_07740 2.5e-23 114.8 Lactobacillaceae ywkB ko:K07088 ko00000 Bacteria 1VDS9@1239,3F5JF@33958,4HQT5@91061,COG0679@1,COG0679@2 NA|NA|NA S Membrane transport protein KIAJIJGH_00438 334390.LAF_0940 9.2e-203 712.6 Lactobacillaceae xerS GO:0000150,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360 ko:K04763 ko00000,ko03036 Bacteria 1URNQ@1239,3FBHV@33958,4HEPI@91061,COG4974@1,COG4974@2 NA|NA|NA L Belongs to the 'phage' integrase family KIAJIJGH_00439 334390.LAF_0941 7.2e-180 636.3 Lactobacillaceae pva3 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 Bacteria 1TPZS@1239,3F3RA@33958,4HEQ3@91061,COG3049@1,COG3049@2 NA|NA|NA M Linear amide C-N hydrolase, choloylglycine hydrolase family protein KIAJIJGH_00440 334390.LAF_0942 3.2e-225 787.3 Lactobacillaceae 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 Bacteria 1TP5G@1239,3F4JX@33958,4H9PE@91061,COG1168@1,COG1168@2 NA|NA|NA E Aminotransferase, class I KIAJIJGH_00441 334390.LAF_0943 3.1e-195 687.6 Lactobacillaceae bdhA 1.1.1.303,1.1.1.4 ko:K00004 ko00650,map00650 R02855,R02946,R10504 RC00205,RC00525 ko00000,ko00001,ko01000 Bacteria 1TPWP@1239,3F3WG@33958,4HABC@91061,COG1063@1,COG1063@2 NA|NA|NA C Zinc-binding dehydrogenase KIAJIJGH_00442 334390.LAF_0944 1.7e-145 521.9 Lactobacillaceae Bacteria 1TPGA@1239,3F4HK@33958,4HER3@91061,COG0604@1,COG0604@2 NA|NA|NA C Zinc-binding dehydrogenase KIAJIJGH_00443 334390.LAF_0945 3.1e-102 377.9 Lactobacillaceae proW ko:K05846 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 1UHWH@1239,3F5XQ@33958,4HJIP@91061,COG1174@1,COG1174@2 NA|NA|NA P ABC transporter, permease protein KIAJIJGH_00444 334390.LAF_0946 2.7e-140 504.6 Lactobacillaceae proV ko:K05847 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 1TPV8@1239,3F55H@33958,4H9SI@91061,COG1125@1,COG1125@2 NA|NA|NA E ABC transporter, ATP-binding protein KIAJIJGH_00445 334390.LAF_0947 1.8e-108 398.7 Lactobacillaceae proWZ ko:K05846 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 1V41S@1239,3FB48@33958,4HH8U@91061,COG1174@1,COG1174@2 NA|NA|NA P ABC transporter permease KIAJIJGH_00446 334390.LAF_0948 1.7e-162 578.6 Lactobacillaceae proX ko:K05845 ko02010,map02010 M00209 ko00000,ko00001,ko00002,ko02000 3.A.1.12 Bacteria 1TQ7D@1239,3FB49@33958,4HESS@91061,COG1732@1,COG1732@2 NA|NA|NA M ABC transporter, substrate-binding protein, QAT family KIAJIJGH_00447 334390.LAF_0949 8.1e-76 289.7 Lactobacillaceae Bacteria 1V6FK@1239,3F73Q@33958,4HKZD@91061,COG1959@1,COG1959@2 NA|NA|NA K Transcriptional regulator KIAJIJGH_00448 334390.LAF_0950 4.2e-74 283.9 Bacilli Bacteria 1V7SN@1239,4HJHJ@91061,COG1765@1,COG1765@2 NA|NA|NA O OsmC-like protein KIAJIJGH_00449 334390.LAF_0951 8.6e-53 212.6 Lactobacillaceae paiA GO:0003674,GO:0003824,GO:0004145,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0043937,GO:0043939,GO:0044424,GO:0044464,GO:0048519,GO:0050789,GO:0050793,GO:0051093,GO:0065007 2.3.1.57 ko:K22441 ko00000,ko01000 Bacteria 1V1RG@1239,3F73H@33958,4HFN7@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain KIAJIJGH_00450 334390.LAF_0951 2e-09 68.2 Lactobacillaceae paiA GO:0003674,GO:0003824,GO:0004145,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0043937,GO:0043939,GO:0044424,GO:0044464,GO:0048519,GO:0050789,GO:0050793,GO:0051093,GO:0065007 2.3.1.57 ko:K22441 ko00000,ko01000 Bacteria 1V1RG@1239,3F73H@33958,4HFN7@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain KIAJIJGH_00451 908339.HMPREF9265_0599 2.2e-25 122.5 Lactobacillaceae Bacteria 1V465@1239,3F7H7@33958,4HN5X@91061,COG0716@1,COG0716@2 NA|NA|NA C Flavodoxin KIAJIJGH_00453 1074451.CRL705_1940 3.2e-158 564.3 Lactobacillaceae Bacteria 1TRSF@1239,3F4DZ@33958,4HCMP@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair KIAJIJGH_00455 334390.LAF_1409 7.1e-167 593.2 Lactobacillaceae yfdH 2.4.2.53 ko:K10012,ko:K12999,ko:K13670 ko00520,ko01503,map00520,map01503 M00721,M00761 R07661 RC00005,RC02954 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko02000 4.D.2.1.8 GT2 Bacteria 1UHWE@1239,3F3JX@33958,4ISA4@91061,COG1216@1,COG1216@2 NA|NA|NA M Glycosyltransferase, group 2 family protein KIAJIJGH_00456 334390.LAF_1745 1.4e-281 974.9 Lactobacillaceae yjeM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 1TRFS@1239,3F4J0@33958,4HA0N@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino Acid KIAJIJGH_00458 566552.BIFCAT_00349 3.2e-63 248.4 Bifidobacteriales 3.2.1.55 ko:K01209 ko00520,map00520 R01762 ko00000,ko00001,ko01000 GH51 Bacteria 2GMAK@201174,4CZS3@85004,COG3534@1,COG3534@2 NA|NA|NA G Alpha-L-arabinofuranosidase C-terminus KIAJIJGH_00459 575594.ACOH01000006_gene161 1.2e-78 300.1 Lactobacillaceae mleR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 Bacteria 1V5VW@1239,3F5D2@33958,4HHDY@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR family KIAJIJGH_00460 525309.HMPREF0494_0743 4.2e-231 807.4 Lactobacillaceae sfcA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0030145,GO:0036094,GO:0043167,GO:0043169,GO:0043464,GO:0044237,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.1.1.38,4.1.1.101 ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 R00214,R11074 RC00105,RC00282 ko00000,ko00001,ko01000 Bacteria 1TPJ3@1239,3F3RH@33958,4HBF1@91061,COG0281@1,COG0281@2 NA|NA|NA C Malic enzyme KIAJIJGH_00461 1203076.CAKF01000025_gene930 6e-183 647.1 Lactobacillaceae XK27_09615 Bacteria 1TPRA@1239,3F44U@33958,4HDA5@91061,COG0431@1,COG0431@2,COG2461@1,COG2461@2 NA|NA|NA S reductase KIAJIJGH_00462 1203076.CAKF01000025_gene929 1.9e-91 342.0 Lactobacillaceae XK27_09620 Bacteria 1TT2S@1239,3F544@33958,4HBQI@91061,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase KIAJIJGH_00463 525309.HMPREF0494_0744 1.6e-223 781.9 Lactobacillaceae fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHPH@1239,3F3K0@33958,4HA6P@91061,COG0114@1,COG0114@2 NA|NA|NA C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate KIAJIJGH_00464 944562.HMPREF9102_1362 3e-214 751.1 Lactobacillaceae frdC 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPAR@1239,3F3KJ@33958,4HAXN@91061,COG1053@1,COG1053@2 NA|NA|NA C FAD binding domain KIAJIJGH_00465 557436.Lreu_1529 1.9e-224 785.0 Lactobacillaceae yflS ko:K03319 ko00000 2.A.47 Bacteria 1TSGE@1239,3F4RH@33958,4HDE4@91061,COG0471@1,COG0471@2 NA|NA|NA P Sodium:sulfate symporter transmembrane region KIAJIJGH_00466 334390.LAF_1565 1.7e-162 578.6 Lactobacillaceae mleR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 Bacteria 1TQ6Y@1239,3FC6N@33958,4HB94@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR family transcriptional regulator KIAJIJGH_00467 334390.LAF_1564 1.6e-252 878.2 Lactobacillaceae yjjP Bacteria 1TNZH@1239,3F4FR@33958,4HU4D@91061,COG2966@1,COG2966@2,COG3610@1,COG3610@2 NA|NA|NA S Putative threonine/serine exporter KIAJIJGH_00468 334390.LAF_1563 2.1e-120 438.3 Lactobacillaceae ung2 3.2.2.27 ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1V4M9@1239,3FB9B@33958,4HMW1@91061,COG1573@1,COG1573@2 NA|NA|NA L Uracil-DNA glycosylase KIAJIJGH_00469 334390.LAF_1562 2.4e-189 667.9 Lactobacillaceae Bacteria 1V1HV@1239,3F5YJ@33958,4HE9T@91061,COG0657@1,COG0657@2 NA|NA|NA I Alpha beta KIAJIJGH_00470 334390.LAF_1561 5.1e-107 393.7 Lactobacillaceae thiJ 2.7.11.1,3.5.1.124 ko:K03152,ko:K05520,ko:K12132 ko00000,ko01000,ko01001,ko01002 Bacteria 1V3UV@1239,3F3T7@33958,4IQYM@91061,COG0693@1,COG0693@2 NA|NA|NA S DJ-1/PfpI family KIAJIJGH_00471 334390.LAF_1560 0.0 1683.3 Lactobacillaceae mprF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 ko:K07027,ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00726 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 2.A.1.3.37,4.D.2 iYO844.BG12900 Bacteria 1TQI2@1239,3F3PY@33958,4HBHU@91061,COG0392@1,COG0392@2,COG2898@1,COG2898@2 NA|NA|NA S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms KIAJIJGH_00473 334390.LAF_1559 9e-172 609.4 Lactobacillaceae rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 ko00000,ko01000,ko03009,ko03016 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 1TS1T@1239,3F46Z@33958,4HBRY@91061,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil KIAJIJGH_00474 334390.LAF_1558 4.4e-310 1069.7 Lactobacillaceae araB 2.7.1.12,2.7.1.16,2.7.1.17 ko:K00851,ko:K00853,ko:K00854 ko00030,ko00040,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map01100,map01110,map01120,map01130,map01200 M00014 R01526,R01639,R01737,R02439 RC00002,RC00017,RC00538 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP91@1239,3F4HI@33958,4HBGF@91061,COG1070@1,COG1070@2 NA|NA|NA G carbohydrate kinase FGGY KIAJIJGH_00475 334390.LAF_1557 1.2e-137 495.7 Lactobacillaceae araD 4.1.2.17,5.1.3.4 ko:K01628,ko:K03077 ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120 M00550 R02262,R05850 RC00603,RC00604,RC01479 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS00590 Bacteria 1TPDV@1239,3F43P@33958,4H9W0@91061,COG0235@1,COG0235@2 NA|NA|NA G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source KIAJIJGH_00476 334390.LAF_1556 9.9e-205 719.2 Lactobacillaceae araR ko:K02103 ko00000,ko03000 Bacteria 1TP9Q@1239,3F3ZM@33958,4HARD@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator KIAJIJGH_00477 334390.LAF_1555 3.1e-248 864.0 Lactobacillaceae araP ko:K06609,ko:K08139,ko:K08368 ko04113,map04113 ko00000,ko00001,ko02000 2.A.1,2.A.1.1,2.A.1.1.26 Bacteria 1UHPS@1239,3FBSI@33958,4IS5K@91061,COG0477@1,COG0477@2 NA|NA|NA U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family KIAJIJGH_00478 334390.LAF_1554 3.4e-285 986.9 Lactobacillaceae araA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008733,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.3.1.4 ko:K01804 ko00040,ko01100,map00040,map01100 R01761 RC00516 ko00000,ko00001,ko01000 iAPECO1_1312.APECO1_1922,iB21_1397.B21_00063,iBWG_1329.BWG_0058,iE2348C_1286.E2348C_0063,iECBD_1354.ECBD_3555,iECD_1391.ECD_00064,iECED1_1282.ECED1_0061,iECIAI1_1343.ECIAI1_0062,iECNA114_1301.ECNA114_0050,iECO103_1326.ECO103_0063,iECO26_1355.ECO26_0064,iECOK1_1307.ECOK1_0061,iECP_1309.ECP_0063,iECS88_1305.ECS88_0065,iECSE_1348.ECSE_0062,iECW_1372.ECW_m0060,iEKO11_1354.EKO11_3852,iEcE24377_1341.EcE24377A_0064,iEcHS_1320.EcHS_A0066,iEcSMS35_1347.EcSMS35_0064,iEcolC_1368.EcolC_3595,iLF82_1304.LF82_0105,iLJ478.TM0276,iNRG857_1313.NRG857_00320,iSBO_1134.SBO_0049,iSSON_1240.SSON_0068,iUMN146_1321.UM146_23095,iUTI89_1310.UTI89_C0067,iWFL_1372.ECW_m0060 Bacteria 1TPXC@1239,3F4PN@33958,4HAWS@91061,COG2160@1,COG2160@2 NA|NA|NA G Catalyzes the conversion of L-arabinose to L-ribulose KIAJIJGH_00479 334390.LAF_1553 9.9e-113 412.9 Lactobacillaceae Bacteria 1VDDQ@1239,2C9UQ@1,32RPZ@2,3F5X9@33958,4HNJB@91061 NA|NA|NA S Domain of unknown function (DUF4811) KIAJIJGH_00480 334390.LAF_1552 6.6e-268 929.5 Lactobacillaceae lmrB Bacteria 1TPRN@1239,3F4A2@33958,4H9VV@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily KIAJIJGH_00481 334390.LAF_1551 1.9e-74 285.0 Lactobacillaceae merR ko:K21089,ko:K21972,ko:K22491 ko02026,map02026 ko00000,ko00001,ko03000 Bacteria 1VDPP@1239,3F6MS@33958,4HPJY@91061,COG0789@1,COG0789@2 NA|NA|NA K MerR HTH family regulatory protein KIAJIJGH_00482 334390.LAF_1550 9.8e-58 229.2 Lactobacillaceae Bacteria 1U6UA@1239,29PSZ@1,30AM0@2,3F8HW@33958,4IGN4@91061 NA|NA|NA KIAJIJGH_00483 334390.LAF_1549 0.0 1213.7 Lactobacillaceae rnjA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1TQ9G@1239,3F3TT@33958,4HAAP@91061,COG0595@1,COG0595@2 NA|NA|NA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay KIAJIJGH_00484 334390.LAF_1548 1.7e-216 758.4 Lactobacillaceae ko:K07052 ko00000 Bacteria 1VNA9@1239,3F5T9@33958,4HRMP@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity KIAJIJGH_00485 908339.HMPREF9265_1546 8.1e-33 146.7 Lactobacillaceae elaA GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 ko:K02348 ko00000 Bacteria 1VAJY@1239,3F5B8@33958,4HIH7@91061,COG2153@1,COG2153@2 NA|NA|NA S GNAT family KIAJIJGH_00486 334390.LAF_1547 4.5e-85 320.5 Lactobacillaceae usp1 Bacteria 1V8UY@1239,3F6N5@33958,4HK2J@91061,COG0589@1,COG0589@2 NA|NA|NA T Belongs to the universal stress protein A family KIAJIJGH_00487 334390.LAF_1546 4.5e-110 404.1 Lactobacillaceae Bacteria 1V6KW@1239,3FBCU@33958,4HEC6@91061,COG1814@1,COG1814@2 NA|NA|NA S VIT family KIAJIJGH_00488 334390.LAF_1545 2.5e-116 424.9 Lactobacillaceae Bacteria 1V26W@1239,3F3TU@33958,4HGMW@91061,COG1814@1,COG1814@2 NA|NA|NA S membrane KIAJIJGH_00489 334390.LAF_1544 4.6e-163 580.5 Lactobacillaceae czcD ko:K16264 ko00000,ko02000 2.A.4.1 Bacteria 1TR92@1239,3F4KJ@33958,4HBCQ@91061,COG1230@1,COG1230@2 NA|NA|NA P cation diffusion facilitator family transporter KIAJIJGH_00490 334390.LAF_1543 1.2e-123 449.1 Lactobacillaceae sirR ko:K03709 ko00000,ko03000 Bacteria 1V3IS@1239,3F405@33958,4HH06@91061,COG1321@1,COG1321@2 NA|NA|NA K iron dependent repressor KIAJIJGH_00491 334390.LAF_1542 1.3e-30 138.3 Lactobacillaceae cspA ko:K03704 ko00000,ko03000 Bacteria 1VEE0@1239,3F7FW@33958,4HNJC@91061,COG1278@1,COG1278@2 NA|NA|NA K Cold shock protein KIAJIJGH_00492 334390.LAF_1541 3.7e-126 457.6 Lactobacillaceae thrE Bacteria 1TSE8@1239,3F4XE@33958,4HBW1@91061,COG2966@1,COG2966@2 NA|NA|NA S Putative threonine/serine exporter KIAJIJGH_00493 334390.LAF_1540 2.8e-82 311.2 Lactobacillaceae Bacteria 1V6P0@1239,3F63I@33958,4HJ1Y@91061,COG3610@1,COG3610@2 NA|NA|NA S Threonine/Serine exporter, ThrE KIAJIJGH_00494 334390.LAF_1539 9.1e-116 422.9 Lactobacillaceae lssY 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 1VY85@1239,3F4DD@33958,4HXM4@91061,COG0671@1,COG0671@2 NA|NA|NA I phosphatase KIAJIJGH_00495 334390.LAF_1538 8.3e-156 556.2 Lactobacillaceae Bacteria 1V7DQ@1239,3FBDR@33958,4HK24@91061,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold KIAJIJGH_00497 334390.LAF_1536 1.1e-267 928.7 Lactobacillaceae lysP ko:K03293,ko:K11733,ko:K16235 ko00000,ko02000 2.A.3.1,2.A.3.1.10,2.A.3.1.2 Bacteria 1UHNR@1239,3F4BG@33958,4HUT7@91061,COG0833@1,COG0833@2 NA|NA|NA E amino acid KIAJIJGH_00498 334390.LAF_1535 7.9e-117 426.4 Lactobacillaceae dak 2.7.1.74,2.7.1.76 ko:K00893,ko:K10353 ko00230,ko00240,ko01100,map00230,map00240,map01100 R00185,R01666,R02089 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TPJ1@1239,3F488@33958,4HA9N@91061,COG1428@1,COG1428@2 NA|NA|NA F deoxynucleoside kinase KIAJIJGH_00504 1302286.BAOT01000038_gene1514 1e-10 72.0 Lactobacillaceae Bacteria 1TSND@1239,3FC9R@33958,4HAU2@91061,COG1028@1,COG1028@2 NA|NA|NA IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) KIAJIJGH_00505 1345023.M467_05945 1.3e-45 189.1 Bacilli Bacteria 1TSND@1239,4HAU2@91061,COG1028@1,COG1028@2 NA|NA|NA IQ reductase KIAJIJGH_00506 334390.LAF_1534 1.1e-147 529.3 Lactobacillaceae uppP GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031224,GO:0031226,GO:0042221,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050380,GO:0050896,GO:0071944 3.6.1.27 ko:K06153 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 iYL1228.KPN_03461 Bacteria 1TPFA@1239,3F510@33958,4HB0M@91061,COG1968@1,COG1968@2 NA|NA|NA V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin KIAJIJGH_00507 525318.HMPREF0497_0297 1.8e-53 215.7 Lactobacillaceae ko:K16925 M00582 ko00000,ko00002,ko02000 3.A.1.30 Bacteria 1V2RP@1239,3FBNY@33958,4HGBA@91061,COG4721@1,COG4721@2 NA|NA|NA S ABC-type cobalt transport system, permease component KIAJIJGH_00509 334390.LAF_1531 4.2e-121 440.7 Lactobacillaceae Bacteria 1VEKU@1239,3F6IQ@33958,4I0FI@91061,COG1514@1,COG1514@2 NA|NA|NA J 2'-5' RNA ligase superfamily KIAJIJGH_00510 334390.LAF_1530 4.3e-132 477.2 Lactobacillaceae XK27_07210 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TT38@1239,3F4C9@33958,4HCE2@91061,COG3382@1,COG3382@2 NA|NA|NA S B3 4 domain KIAJIJGH_00511 334390.LAF_1528 9.7e-194 682.6 Lactobacillaceae adhP GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0006081,GO:0006117,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009636,GO:0009987,GO:0010033,GO:0016491,GO:0016614,GO:0016616,GO:0033554,GO:0042221,GO:0042493,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0045471,GO:0046185,GO:0046187,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0097305,GO:1901575,GO:1901700 1.1.1.1 ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 iECP_1309.ECP_1480 Bacteria 1TP5B@1239,3F4PR@33958,4HA9Z@91061,COG1064@1,COG1064@2 NA|NA|NA C alcohol dehydrogenase KIAJIJGH_00512 334390.LAF_1527 4.8e-79 300.4 Lactobacillaceae ctsR GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 ko:K03708 ko00000,ko03000 Bacteria 1VAXT@1239,3F53E@33958,4HIFT@91061,COG4463@1,COG4463@2 NA|NA|NA K Belongs to the CtsR family KIAJIJGH_00513 334390.LAF_1526 0.0 1583.5 Lactobacillaceae clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 ko:K03696 ko01100,map01100 ko00000,ko03110 Bacteria 1TPMU@1239,3F3RV@33958,4HACY@91061,COG0542@1,COG0542@2 NA|NA|NA O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE KIAJIJGH_00514 334390.LAF_1525 5.8e-106 390.2 Lactobacillaceae ko:K09017 ko00000,ko03000 Bacteria 1UYPI@1239,3FBFF@33958,4IQ2E@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family KIAJIJGH_00515 334390.LAF_1523 0.0 2373.2 Lactobacillaceae rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1TP96@1239,3F4ET@33958,4H9PK@91061,COG0085@1,COG0085@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates KIAJIJGH_00516 334390.LAF_1522 0.0 2389.0 Lactobacillaceae rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1TNYT@1239,3F3KF@33958,4HA24@91061,COG0086@1,COG0086@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates KIAJIJGH_00517 334390.LAF_1521 2.5e-135 488.0 Lactobacillaceae puuD ko:K07010 ko00000,ko01002 Bacteria 1V1KC@1239,3F4PK@33958,4HI59@91061,COG2071@1,COG2071@2 NA|NA|NA S peptidase C26 KIAJIJGH_00518 334390.LAF_1520 7.4e-214 749.6 Lactobacillaceae ykiI Bacteria 1VRBZ@1239,2DSXT@1,32UTZ@2,3F4NM@33958,4HT22@91061 NA|NA|NA KIAJIJGH_00519 1203076.CAKF01000019_gene1273 4.7e-32 144.8 Bacteria pilD 3.4.23.43 ko:K02236,ko:K02506,ko:K02654 M00331,M00429 ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 Bacteria COG1989@1,COG1989@2 NA|NA|NA NOU aspartic-type endopeptidase activity KIAJIJGH_00520 334390.LAF_1519 3.2e-71 274.2 Lactobacillaceae rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02950 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1FJ@1239,3F64B@33958,4HFMZ@91061,COG0048@1,COG0048@2 NA|NA|NA J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit KIAJIJGH_00521 334390.LAF_1518 7.1e-83 313.2 Lactobacillaceae rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02992 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1GG@1239,3F3RX@33958,4H9PA@91061,COG0049@1,COG0049@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA KIAJIJGH_00522 334390.LAF_1517 0.0 1370.1 Lactobacillaceae fusA GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02355 ko00000,ko03012,ko03029 Bacteria 1TPF9@1239,3F3JR@33958,4HAB8@91061,COG0480@1,COG0480@2 NA|NA|NA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome KIAJIJGH_00523 334390.LAF_1516 2.6e-49 201.1 Lactobacillaceae rpsJ GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 ko:K02946 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6C9@1239,3F6KC@33958,4HIKH@91061,COG0051@1,COG0051@2 NA|NA|NA J Involved in the binding of tRNA to the ribosomes KIAJIJGH_00524 334390.LAF_1515 8.7e-119 433.0 Lactobacillaceae rplC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 ko:K02906 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPFT@1239,3F45I@33958,4HAEN@91061,COG0087@1,COG0087@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit KIAJIJGH_00525 334390.LAF_1514 2.7e-106 391.3 Lactobacillaceae rplD GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030312,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02926,ko:K16193 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPGW@1239,3F3QD@33958,4HB01@91061,COG0088@1,COG0088@2 NA|NA|NA J Forms part of the polypeptide exit tunnel KIAJIJGH_00526 334390.LAF_1513 4.8e-45 186.8 Lactobacillaceae rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02892 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VA4W@1239,3F6Z2@33958,4HKCV@91061,COG0089@1,COG0089@2 NA|NA|NA J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome KIAJIJGH_00527 334390.LAF_1512 3.2e-150 537.7 Lactobacillaceae rplB GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02886 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TP9X@1239,3F3XI@33958,4HAE8@91061,COG0090@1,COG0090@2 NA|NA|NA J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity KIAJIJGH_00528 334390.LAF_1511 8.4e-47 192.6 Lactobacillaceae rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02965 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6CX@1239,3F6XP@33958,4HIG0@91061,COG0185@1,COG0185@2 NA|NA|NA J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA KIAJIJGH_00529 334390.LAF_1510 2.2e-52 211.5 Lactobacillaceae rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02890 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6PU@1239,3F6K6@33958,4HIK2@91061,COG0091@1,COG0091@2 NA|NA|NA J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome KIAJIJGH_00530 334390.LAF_1509 6.2e-117 426.8 Lactobacillaceae rpsC GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02982 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPCP@1239,3F3Q8@33958,4HAUR@91061,COG0092@1,COG0092@2 NA|NA|NA J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation KIAJIJGH_00531 334390.LAF_1508 6e-76 290.0 Lactobacillaceae rplP GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02878 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1AY@1239,3F653@33958,4HFPN@91061,COG0197@1,COG0197@2 NA|NA|NA J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs KIAJIJGH_00532 334390.LAF_1507 1.1e-27 128.6 Lactobacillaceae rpmC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02904 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEME@1239,3F82Z@33958,4HNUP@91061,COG0255@1,COG0255@2 NA|NA|NA J Belongs to the universal ribosomal protein uL29 family KIAJIJGH_00533 334390.LAF_1506 6.5e-41 172.9 Lactobacillaceae rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02961 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V9YC@1239,3F7FX@33958,4HKDN@91061,COG0186@1,COG0186@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA KIAJIJGH_00534 1203076.CAKF01000017_gene1719 6.6e-60 236.5 Lactobacillaceae rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02874 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3N0@1239,3F6GT@33958,4HGYR@91061,COG0093@1,COG0093@2 NA|NA|NA J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome KIAJIJGH_00535 334390.LAF_1504 5.2e-50 203.4 Lactobacillaceae rplX GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02895 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V9ZQ@1239,3F6X5@33958,4HKH9@91061,COG0198@1,COG0198@2 NA|NA|NA J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit KIAJIJGH_00536 334390.LAF_1503 4.2e-95 354.0 Lactobacillaceae rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02931 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TPE0@1239,3F3Q7@33958,4HBAX@91061,COG0094@1,COG0094@2 NA|NA|NA J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits KIAJIJGH_00537 334390.LAF_1502 5.2e-29 132.9 Lactobacillaceae rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02954 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEF6@1239,3FB5M@33958,4HNKX@91061,COG0199@1,COG0199@2 NA|NA|NA J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site KIAJIJGH_00538 334390.LAF_1501 1e-66 259.2 Lactobacillaceae rpsH GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010608,GO:0015935,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031329,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043487,GO:0043488,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903311,GO:1990904 ko:K02994 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3KK@1239,3F64E@33958,4HH32@91061,COG0096@1,COG0096@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit KIAJIJGH_00539 334390.LAF_1500 5.1e-93 347.1 Lactobacillaceae rplF GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02933 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1FC@1239,3F4G5@33958,4HFQD@91061,COG0097@1,COG0097@2 NA|NA|NA J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center KIAJIJGH_00540 334390.LAF_1499 3.9e-57 227.3 Lactobacillaceae rplR GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02881 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6DM@1239,3F6KN@33958,4HIGF@91061,COG0256@1,COG0256@2 NA|NA|NA J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance KIAJIJGH_00541 334390.LAF_1498 2.6e-86 324.7 Lactobacillaceae rpsE GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 ko:K02988 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V1B1@1239,3F3VY@33958,4HFN4@91061,COG0098@1,COG0098@2 NA|NA|NA J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body KIAJIJGH_00542 334390.LAF_1497 2.5e-23 114.0 Lactobacillaceae rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02907 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEG4@1239,3F7ZU@33958,4HNHF@91061,COG1841@1,COG1841@2 NA|NA|NA J Ribosomal protein L30 KIAJIJGH_00543 334390.LAF_1496 2.1e-65 255.0 Lactobacillaceae rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02876 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3KE@1239,3F675@33958,4HFPW@91061,COG0200@1,COG0200@2 NA|NA|NA J Binds to the 23S rRNA KIAJIJGH_00544 334390.LAF_1495 5.8e-236 823.2 Lactobacillaceae secY GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0040007,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5 Bacteria 1TPHB@1239,3F4FV@33958,4HAWH@91061,COG0201@1,COG0201@2 NA|NA|NA U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently KIAJIJGH_00545 334390.LAF_1494 6.4e-122 443.4 Lactobacillaceae adk GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 iHN637.CLJU_RS20110 Bacteria 1TP27@1239,3F3KB@33958,4HA89@91061,COG0563@1,COG0563@2 NA|NA|NA F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism KIAJIJGH_00546 1203076.CAKF01000017_gene1708 2e-32 144.4 Lactobacillaceae infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009986,GO:0016020,GO:0030246,GO:0030247,GO:0030312,GO:0040007,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071944,GO:2001065 ko:K02518 ko00000,ko03012 Bacteria 1V9ZK@1239,3F7CW@33958,4HKF4@91061,COG0361@1,COG0361@2 NA|NA|NA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex KIAJIJGH_00547 334390.LAF_1492 1.1e-13 81.3 Lactobacillaceae rpmJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02919 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VK4F@1239,3F8TC@33958,4HR2X@91061,COG0257@1,COG0257@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL36 family KIAJIJGH_00548 334390.LAF_1491 9.5e-59 232.6 Lactobacillaceae rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02952 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3JH@1239,3F6GN@33958,4HGX6@91061,COG0099@1,COG0099@2 NA|NA|NA J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits KIAJIJGH_00549 334390.LAF_1490 1e-63 249.2 Lactobacillaceae rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02948 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3IK@1239,3F67D@33958,4HH2T@91061,COG0100@1,COG0100@2 NA|NA|NA J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome KIAJIJGH_00550 334390.LAF_1489 2e-169 601.7 Lactobacillaceae rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1TPR8@1239,3F3W6@33958,4H9R1@91061,COG0202@1,COG0202@2 NA|NA|NA K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates KIAJIJGH_00551 334390.LAF_1488 2.8e-61 241.1 Lactobacillaceae rplQ GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02879,ko:K16193 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6JQ@1239,3F6GJ@33958,4HGX2@91061,COG0203@1,COG0203@2 NA|NA|NA J Ribosomal protein L17 KIAJIJGH_00552 334390.LAF_1487 4.6e-149 533.9 Lactobacillaceae cbiO GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 ko:K16784,ko:K16786,ko:K16787 ko02010,map02010 M00581,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TPH8@1239,3F3VD@33958,4H9R8@91061,COG1122@1,COG1122@2 NA|NA|NA P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates KIAJIJGH_00553 334390.LAF_1486 5.8e-155 553.5 Lactobacillaceae ecfA2 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008144,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032217,GO:0032218,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035461,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0097159,GO:0097367,GO:0098656,GO:1901265,GO:1901363 3.6.3.55 ko:K02068,ko:K06857,ko:K16784,ko:K16786,ko:K16787 ko02010,map02010 M00186,M00211,M00581,M00582 R10531 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35,3.A.1.6.2,3.A.1.6.4 Bacteria 1TPH8@1239,3F48E@33958,4HA7T@91061,COG1122@1,COG1122@2 NA|NA|NA P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates KIAJIJGH_00554 334390.LAF_1485 1.4e-139 502.3 Lactobacillaceae ecfT GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 ko:K02008,ko:K16783,ko:K16785 ko02010,map02010 M00245,M00246,M00581,M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TQ0E@1239,3F3UW@33958,4H9VT@91061,COG0619@1,COG0619@2 NA|NA|NA U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates KIAJIJGH_00555 334390.LAF_1484 6.3e-145 520.0 Lactobacillaceae truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 ko00000,ko01000,ko03016 Bacteria 1TQUY@1239,3F4KC@33958,4HCFI@91061,COG0101@1,COG0101@2 NA|NA|NA J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs KIAJIJGH_00556 334390.LAF_1483 2.6e-79 301.2 Lactobacillaceae rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 ko:K02871 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3HX@1239,3F696@33958,4HG0I@91061,COG0102@1,COG0102@2 NA|NA|NA J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly KIAJIJGH_00557 334390.LAF_1482 1.5e-65 255.4 Lactobacillaceae rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02996 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V3MQ@1239,3F656@33958,4HH3B@91061,COG0103@1,COG0103@2 NA|NA|NA J Belongs to the universal ribosomal protein uS9 family KIAJIJGH_00558 334390.LAF_1481 2e-189 668.3 Lactobacillaceae Bacteria 1UJID@1239,3FBV6@33958,4ITAA@91061,COG3021@1,COG3021@2 NA|NA|NA S interspecies interaction between organisms KIAJIJGH_00559 334390.LAF_1131 1.1e-30 138.7 Lactobacillaceae naiP Bacteria 1TQM0@1239,3F3SE@33958,4HATA@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily KIAJIJGH_00560 334390.LAF_1130 5.3e-251 873.2 Lactobacillaceae yhdP ko:K03699,ko:K06189 ko00000,ko02000,ko02042 9.A.40.1.2 Bacteria 1TPN0@1239,3F3TX@33958,4H9SB@91061,COG1253@1,COG1253@2 NA|NA|NA S Transporter associated domain KIAJIJGH_00561 334390.LAF_1129 5.8e-201 706.8 Lactobacillaceae mdtG GO:0006810,GO:0006855,GO:0008150,GO:0015893,GO:0042221,GO:0042493,GO:0050896,GO:0051179,GO:0051234,GO:0055085 ko:K08161 ko00000,ko02000 2.A.1.2.20 Bacteria 1TRDJ@1239,3F3T5@33958,4H9Q9@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily KIAJIJGH_00562 908339.HMPREF9265_0247 1.2e-159 569.7 Lactobacillaceae ko:K18934 ko00000,ko02000 2.A.1.3.39 Bacteria 1VU5Q@1239,3F3JN@33958,4HUUP@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily KIAJIJGH_00563 334390.LAF_1128 7.7e-168 596.3 Lactobacillaceae Bacteria 1UZK9@1239,3F5JR@33958,4HG1F@91061,COG0639@1,COG0639@2 NA|NA|NA T Calcineurin-like phosphoesterase superfamily domain KIAJIJGH_00564 334390.LAF_1127 2.7e-42 177.6 Lactobacillaceae rpsN GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02954 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEF6@1239,3F7KX@33958,4HKK1@91061,COG0199@1,COG0199@2 NA|NA|NA J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site KIAJIJGH_00565 334390.LAF_1391 4e-76 290.8 Lactobacillaceae pncB GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 R01724 RC00033 ko00000,ko00001,ko01000 Bacteria 1TPDW@1239,3F3K7@33958,4HAI4@91061,COG1488@1,COG1488@2 NA|NA|NA F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP KIAJIJGH_00566 334390.LAF_1390 4.9e-110 403.7 Lactobacillaceae pncA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0017144,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 ko:K16788 ko00000,ko02000 2.A.88.5 iSB619.SA_RS09955 Bacteria 1V1CY@1239,3F41F@33958,4HFRS@91061,COG1335@1,COG1335@2 NA|NA|NA Q Isochorismatase family KIAJIJGH_00567 334390.LAF_1389 6.4e-128 463.4 Lactobacillaceae 3.6.1.13,3.6.1.55 ko:K01515,ko:K03574 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000,ko03400 Bacteria 1UZ4E@1239,3FBCZ@33958,4IPMJ@91061,COG1051@1,COG1051@2,COG4111@1,COG4111@2 NA|NA|NA F NUDIX domain KIAJIJGH_00568 334390.LAF_1388 0.0 1361.7 Lactobacillaceae clpE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03697 ko00000,ko03110 Bacteria 1TPMU@1239,3F3K9@33958,4HA0V@91061,COG0542@1,COG0542@2 NA|NA|NA O Belongs to the ClpA ClpB family KIAJIJGH_00569 334390.LAF_1388 3.1e-16 90.1 Lactobacillaceae clpE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03697 ko00000,ko03110 Bacteria 1TPMU@1239,3F3K9@33958,4HA0V@91061,COG0542@1,COG0542@2 NA|NA|NA O Belongs to the ClpA ClpB family KIAJIJGH_00571 334390.LAF_1386 4.7e-39 166.8 Lactobacillaceae ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007 ko:K11189 ko00000,ko02000 4.A.2.1 Bacteria 1VA0R@1239,3F6XQ@33958,4HKGA@91061,COG1925@1,COG1925@2 NA|NA|NA G phosphocarrier protein HPR KIAJIJGH_00572 334390.LAF_1385 0.0 1118.6 Lactobacillaceae ptsI GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0008150,GO:0008643,GO:0008965,GO:0009401,GO:0016740,GO:0016772,GO:0016775,GO:0019197,GO:0032991,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 8.A.7 iB21_1397.B21_02277,iE2348C_1286.E2348C_2602,iEC042_1314.EC042_2625,iECBD_1354.ECBD_1265,iECB_1328.ECB_02316,iECD_1391.ECD_02316,iECH74115_1262.ECH74115_3647,iECIAI1_1343.ECIAI1_2474,iECIAI39_1322.ECIAI39_2562,iECO103_1326.ECO103_2935,iECO111_1330.ECO111_3146,iECO26_1355.ECO26_3469,iECP_1309.ECP_2440,iECSE_1348.ECSE_2707,iECSP_1301.ECSP_3364,iECUMN_1333.ECUMN_2738,iECW_1372.ECW_m2645,iECs_1301.ECs3288,iEKO11_1354.EKO11_1312,iEcE24377_1341.EcE24377A_2703,iEcHS_1320.EcHS_A2551,iEcSMS35_1347.EcSMS35_2571,iEcolC_1368.EcolC_1262,iLF82_1304.LF82_1770,iNRG857_1313.NRG857_12115,iSBO_1134.SBO_2440,iSDY_1059.SDY_2613,iSFV_1184.SFV_2468,iSF_1195.SF2471,iSFxv_1172.SFxv_2720,iSSON_1240.SSON_2505,iS_1188.S2617,iUMNK88_1353.UMNK88_3018,iWFL_1372.ECW_m2645,iZ_1308.Z3682 Bacteria 1TPK8@1239,3F3MS@33958,4H9VD@91061,COG1080@1,COG1080@2 NA|NA|NA G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) KIAJIJGH_00573 334390.LAF_1384 1.9e-228 798.1 Lactobacillaceae mgs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576 2.4.1.337 ko:K19002 ko00561,ko01100,map00561,map01100 R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 GT4 Bacteria 1TPTA@1239,3F4H5@33958,4HA41@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase, group 1 family protein KIAJIJGH_00574 334390.LAF_1383 6.1e-196 689.9 Lactobacillaceae cpoA GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901576 ko:K13678 R10865 RC00005,RC00049 ko00000,ko01000,ko01003 GT4 Bacteria 1TPSS@1239,3F47X@33958,4HB9F@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyltransferase, group 1 family protein KIAJIJGH_00575 334390.LAF_1382 7.2e-181 639.8 Lactobacillaceae mprF ko:K07027 ko00000,ko02000 4.D.2 Bacteria 1UY7Z@1239,3F3UR@33958,4HCG6@91061,COG0392@1,COG0392@2 NA|NA|NA I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms KIAJIJGH_00576 334390.LAF_1381 9.7e-39 165.6 Lactobacillaceae ykuJ Bacteria 1U6NV@1239,3F87U@33958,4IGFT@91061,COG4703@1,COG4703@2 NA|NA|NA S Protein of unknown function (DUF1797) KIAJIJGH_00577 1211844.CBLM010000075_gene1774 4.2e-66 258.1 Erysipelotrichia ko:K00754 ko00000,ko01000 GT4 Bacteria 1TPY6@1239,3VNVS@526524,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferase 4-like KIAJIJGH_00587 1423814.HMPREF0549_1580 2.3e-24 119.0 Lactobacillaceae Bacteria 1V9I9@1239,3F8NC@33958,4I2U9@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family KIAJIJGH_00589 334390.LAF_1378 1.5e-141 508.8 Lactobacillaceae ko:K02029,ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TT16@1239,3F4YD@33958,4HD16@91061,COG0834@1,COG0834@2 NA|NA|NA ET Bacterial periplasmic substrate-binding proteins KIAJIJGH_00590 334390.LAF_1377 4.5e-110 404.1 Lactobacillaceae XK27_05795 ko:K02029,ko:K02030,ko:K17073,ko:K17074 ko02010,map02010 M00236,M00589 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.20 Bacteria 1TPM3@1239,3F48Y@33958,4HAS2@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter permease KIAJIJGH_00591 334390.LAF_1376 0.0 1510.0 Lactobacillaceae nrdD GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0017076,GO:0018130,GO:0019001,GO:0019103,GO:0019438,GO:0019637,GO:0019692,GO:0030554,GO:0031250,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032556,GO:0032558,GO:0032559,GO:0032560,GO:0032564,GO:0032567,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0046872,GO:0046914,GO:0051065,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_4713,iPC815.YPO3454 Bacteria 1TR9K@1239,3F435@33958,4HBIY@91061,COG1328@1,COG1328@2 NA|NA|NA F Ribonucleoside-triphosphate reductase KIAJIJGH_00592 334390.LAF_0025 4e-228 797.0 Lactobacillaceae mapA 2.4.1.8 ko:K00691 ko00500,ko01100,map00500,map01100 R01555 RC00049 ko00000,ko00001,ko01000 GH65 Bacteria 1TQMB@1239,3F3PG@33958,4HAVB@91061,COG1554@1,COG1554@2 NA|NA|NA G hydrolase, family 65, central catalytic KIAJIJGH_00593 334390.LAF_1440 3.6e-140 504.2 Lactobacillaceae Bacteria 1VBJA@1239,3F41J@33958,4HSVK@91061,COG0431@1,COG0431@2 NA|NA|NA S NADPH-dependent FMN reductase KIAJIJGH_00594 1203076.CAKF01000006_gene499 2.3e-33 148.3 Lactobacillaceae yneR Bacteria 1VEQE@1239,3F7SB@33958,4HNU2@91061,COG4841@1,COG4841@2 NA|NA|NA S Belongs to the HesB IscA family KIAJIJGH_00595 334390.LAF_1441 8.2e-304 1048.9 Lactobacillaceae ybiT GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0050896 ko:K06158 ko00000,ko03012 Bacteria 1TPW0@1239,3F3ZJ@33958,4HATH@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter, ATP-binding protein KIAJIJGH_00596 334390.LAF_1442 1.7e-84 318.5 Lactobacillaceae dps ko:K04047 ko00000,ko03036 Bacteria 1VCVJ@1239,3F5WI@33958,4HMBD@91061,COG0783@1,COG0783@2 NA|NA|NA P Belongs to the Dps family KIAJIJGH_00597 334390.LAF_1443 6e-105 386.7 Lactobacillaceae Bacteria 1VUSY@1239,2AYWY@1,3354X@2,3FC0S@33958,4HVEY@91061 NA|NA|NA KIAJIJGH_00598 334390.LAF_1444 1.3e-184 652.5 Lactobacillaceae brpA Bacteria 1TR1B@1239,3F3MQ@33958,4HA09@91061,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-like function transcriptional attenuator common domain protein KIAJIJGH_00599 334390.LAF_1445 1.4e-101 375.6 Bacilli Bacteria 1VQ2Q@1239,4HS36@91061,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein KIAJIJGH_00600 575594.ACOH01000002_gene989 3.4e-49 201.1 Bacilli fsr ko:K08223 ko00000,ko02000 2.A.1.35 Bacteria 1UJ0G@1239,4ITTG@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major Facilitator Superfamily KIAJIJGH_00601 575594.ACOH01000002_gene989 3e-26 124.4 Bacilli fsr ko:K08223 ko00000,ko02000 2.A.1.35 Bacteria 1UJ0G@1239,4ITTG@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major Facilitator Superfamily KIAJIJGH_00602 334390.LAF_1446 9.2e-100 369.4 Lactobacillaceae ogt GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63,3.2.2.20 ko:K00567,ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1V2MB@1239,3FBD8@33958,4HJGF@91061,COG0350@1,COG0350@2 NA|NA|NA L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated KIAJIJGH_00603 334390.LAF_1447 7.8e-103 379.8 Bacilli Bacteria 1VBYM@1239,4HM2K@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity KIAJIJGH_00605 334390.LAF_1449 1.4e-119 435.6 Lactobacillaceae Bacteria 1UHIX@1239,3F695@33958,4HFT8@91061,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase domain KIAJIJGH_00606 334390.LAF_1450 7.8e-72 276.6 Lactobacillaceae 1.5.1.40 ko:K06988 ko00000,ko01000 Bacteria 1V35D@1239,3F5EP@33958,4HFSW@91061,COG2085@1,COG2085@2 NA|NA|NA S NADP oxidoreductase coenzyme F420-dependent KIAJIJGH_00607 334390.LAF_1449 5.9e-46 189.9 Lactobacillaceae Bacteria 1UHIX@1239,3F695@33958,4HFT8@91061,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase domain KIAJIJGH_00608 334390.LAF_1450 2.3e-21 107.5 Lactobacillaceae 1.5.1.40 ko:K06988 ko00000,ko01000 Bacteria 1V35D@1239,3F5EP@33958,4HFSW@91061,COG2085@1,COG2085@2 NA|NA|NA S NADP oxidoreductase coenzyme F420-dependent KIAJIJGH_00609 334390.LAF_1450 2e-58 231.5 Lactobacillaceae 1.5.1.40 ko:K06988 ko00000,ko01000 Bacteria 1V35D@1239,3F5EP@33958,4HFSW@91061,COG2085@1,COG2085@2 NA|NA|NA S NADP oxidoreductase coenzyme F420-dependent KIAJIJGH_00610 334390.LAF_1451 2.8e-51 207.6 Bacteria Bacteria COG1959@1,COG1959@2 NA|NA|NA K 2 iron, 2 sulfur cluster binding KIAJIJGH_00611 334390.LAF_1452 0.0 1087.0 Lactobacillaceae mco Bacteria 1TQSU@1239,3F3XB@33958,4HDD6@91061,COG2132@1,COG2132@2 NA|NA|NA Q Multicopper oxidase KIAJIJGH_00612 334390.LAF_1453 7.1e-89 333.2 Lactobacillaceae ko:K19055 ko00000,ko01000,ko03016 Bacteria 1V29H@1239,3F6ZD@33958,4HP8F@91061,COG3760@1,COG3760@2 NA|NA|NA S Aminoacyl-tRNA editing domain KIAJIJGH_00613 334390.LAF_1455 1.2e-74 286.6 Lactobacillaceae ddaH 3.5.3.18 ko:K01482 ko00000,ko01000,ko04147 Bacteria 1TRPV@1239,3FA93@33958,4H9YU@91061,COG1834@1,COG1834@2 NA|NA|NA E Amidinotransferase KIAJIJGH_00615 334390.LAF_1456 2.3e-193 681.8 Lactobacillaceae nhaC ko:K03315 ko00000,ko02000 2.A.35 Bacteria 1TQ3B@1239,3F3VX@33958,4HA18@91061,COG1757@1,COG1757@2 NA|NA|NA C Na H antiporter NhaC KIAJIJGH_00616 525318.HMPREF0497_1943 1.9e-186 658.7 Lactobacillaceae metY 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 Bacteria 1VYCY@1239,3FBSS@33958,4H9X5@91061,COG2873@1,COG2873@2 NA|NA|NA E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol KIAJIJGH_00618 334390.LAF_0973 3.4e-211 740.7 Lactobacillaceae metC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.5.1.48,4.4.1.1,4.4.1.2,4.4.1.8 ko:K01739,ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00609 R00782,R00999,R01001,R01283,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPC7@1239,3F3Y2@33958,4HAFQ@91061,COG0626@1,COG0626@2 NA|NA|NA E cystathionine KIAJIJGH_00619 334390.LAF_0974 1.3e-168 599.0 Lactobacillaceae mccA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042127,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0065007,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.134,2.5.1.47 ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00609 R00897,R03601,R04859,R10305 RC00020,RC00069,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS02385 Bacteria 1TP30@1239,3F4VD@33958,4HAMU@91061,COG0031@1,COG0031@2 NA|NA|NA E Belongs to the cysteine synthase cystathionine beta- synthase family KIAJIJGH_00620 334390.LAF_0975 2.5e-40 171.0 Lactobacillaceae gcvR ko:K07166 ko00000 Bacteria 1VENW@1239,3F811@33958,4HNJ4@91061,COG3830@1,COG3830@2 NA|NA|NA T Belongs to the UPF0237 family KIAJIJGH_00621 334390.LAF_0976 9.3e-245 852.4 Lactobacillaceae XK27_08635 ko:K09157 ko00000 Bacteria 1TQG8@1239,3F4H2@33958,4HBTU@91061,COG2848@1,COG2848@2 NA|NA|NA S UPF0210 protein KIAJIJGH_00622 334390.LAF_0977 1.6e-137 495.4 Lactobacillaceae yobV1 Bacteria 1U8E4@1239,3FBID@33958,4IQQI@91061,COG2378@1,COG2378@2 NA|NA|NA K WYL domain KIAJIJGH_00623 1423748.BALB01000032_gene1934 9.2e-156 557.0 Lactobacillaceae Bacteria 1U8FY@1239,3F5K1@33958,4HEX0@91061,COG2865@1,COG2865@2 NA|NA|NA K Putative DNA-binding domain KIAJIJGH_00625 1114972.AUAW01000013_gene1023 2.7e-52 213.8 Bacilli ruvB 3.6.4.12 ko:K03551,ko:K07126 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1V0DS@1239,4HENV@91061,COG2255@1,COG2255@2 NA|NA|NA L four-way junction helicase activity KIAJIJGH_00626 1089548.KI783301_gene1618 1.6e-37 163.3 Bacillales incertae sedis sigA GO:0000988,GO:0000990,GO:0001098,GO:0001101,GO:0001108,GO:0001666,GO:0002791,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0016020,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032879,GO:0032880,GO:0036293,GO:0040007,GO:0042221,GO:0043175,GO:0043254,GO:0044087,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051173,GO:0051223,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070063,GO:0070201,GO:0070482,GO:0071944,GO:0080090,GO:0090087,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:1903530,GO:2000112,GO:2000142,GO:2001141 ko:K03086,ko:K03087 ko02026,ko05111,map02026,map05111 ko00000,ko00001,ko03021 Bacteria 1TPD6@1239,3WEKG@539002,4HB1H@91061,COG0568@1,COG0568@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth KIAJIJGH_00629 326425.lhe_0467 6.4e-73 280.8 Lactobacillaceae endA ko:K15051 ko00000 Bacteria 1V4X2@1239,3F3Y8@33958,4HIF5@91061,COG2169@1,COG2169@2 NA|NA|NA F DNA RNA non-specific endonuclease KIAJIJGH_00634 203120.LEUM_1263 6.2e-09 68.6 Leuconostocaceae Bacteria 1TWD0@1239,29HCI@1,304A1@2,4AXIK@81850,4I54P@91061 NA|NA|NA KIAJIJGH_00636 883103.HMPREF9703_00040 7.1e-18 97.1 Carnobacteriaceae 1.20.4.1 ko:K00537 ko00000,ko01000 Bacteria 1V3QC@1239,27G9F@186828,4HH0I@91061,COG1393@1,COG1393@2 NA|NA|NA P ArsC family KIAJIJGH_00645 1423724.BAMM01000020_gene1808 2.3e-15 90.1 Bacteria Bacteria COG3756@1,COG3756@2 NA|NA|NA KIAJIJGH_00648 913848.AELK01000153_gene2001 2.9e-11 74.7 Bacteria Bacteria COG4707@1,COG4707@2 NA|NA|NA S Domain of unknown function (DUF771) KIAJIJGH_00650 1280.SAXN108_0312 2.7e-11 75.1 Staphylococcaceae XK27_10050 Bacteria 1VAT3@1239,4GZJ7@90964,4HM0X@91061,COG1396@1,COG1396@2,COG2932@1,COG2932@2 NA|NA|NA K Peptidase S24-like KIAJIJGH_00651 1423815.BACR01000010_gene590 3.9e-09 68.2 Lactobacillaceae Bacteria 1W1K0@1239,3F81Z@33958,4IGCD@91061,COG2856@1,COG2856@2 NA|NA|NA E Zn peptidase KIAJIJGH_00652 334390.LAF_0657 6.5e-90 337.8 Lactobacillaceae Bacteria 1TPE1@1239,3F3NJ@33958,4HA65@91061,COG0582@1,COG0582@2 NA|NA|NA L Belongs to the 'phage' integrase family KIAJIJGH_00653 334390.LAF_0106 2.1e-93 348.2 Lactobacillaceae ko:K09705 ko00000 Bacteria 1V52Y@1239,3F77H@33958,4HH9T@91061,COG3542@1,COG3542@2 NA|NA|NA S Cupin superfamily (DUF985) KIAJIJGH_00654 334390.LAF_0085 4.5e-68 263.8 Lactobacillaceae epsB Bacteria 1UZCR@1239,3F4M5@33958,4HE26@91061,COG3944@1,COG3944@2 NA|NA|NA M biosynthesis protein KIAJIJGH_00655 334390.LAF_0086 1.4e-114 419.1 Lactobacillaceae ywqD 2.7.10.1 ko:K08252,ko:K16554 ko05111,map05111 ko00000,ko00001,ko01000,ko02000 8.A.3.1 Bacteria 1TS4R@1239,3F4BM@33958,4HCEN@91061,COG0489@1,COG0489@2 NA|NA|NA D Capsular exopolysaccharide family KIAJIJGH_00656 334390.LAF_0108 1e-204 719.2 Lactobacillaceae hpk31 2.7.13.3 ko:K07636 ko02020,map02020 M00434 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TPB6@1239,3F479@33958,4HARU@91061,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase KIAJIJGH_00657 511437.Lbuc_2419 5.3e-95 354.0 Lactobacillaceae tuaA Bacteria 1TP7M@1239,3F5PC@33958,4HB15@91061,COG2148@1,COG2148@2 NA|NA|NA M Bacterial sugar transferase KIAJIJGH_00658 511437.Lbuc_2420 2e-40 171.8 Lactobacillaceae cps2D 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS00780 Bacteria 1V34Y@1239,3F5GY@33958,4HCJE@91061,COG0451@1,COG0451@2 NA|NA|NA M RmlD substrate binding domain KIAJIJGH_00659 334390.LAF_1074 1.4e-111 409.1 Lactobacillaceae hepT 2.5.1.30,2.5.1.90 ko:K00805,ko:K02251,ko:K02523 ko00900,ko01110,ko02024,map00900,map01110,map02024 R09247,R09248 RC00279 ko00000,ko00001,ko01000,ko01006,ko02044 Bacteria 1UFPZ@1239,3F4NS@33958,4IEVZ@91061,COG0142@1,COG0142@2 NA|NA|NA H geranyltranstransferase activity KIAJIJGH_00661 334390.LAF_1076 1e-133 482.6 Lactobacillaceae menG GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQEA@1239,3F3R2@33958,4HAR9@91061,COG0500@1,COG2226@2 NA|NA|NA H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) KIAJIJGH_00662 334390.LAF_1077 2.1e-160 571.6 Lactobacillaceae hipB GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K15773 ko00000,ko02048,ko03000 Bacteria 1VDMN@1239,3F5A3@33958,4HDVP@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix KIAJIJGH_00663 334390.LAF_1078 1.5e-58 231.9 Lactobacillaceae yitW ko:K02612 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 1VCAX@1239,3FCDE@33958,4HNBK@91061,COG2151@1,COG2151@2 NA|NA|NA S Iron-sulfur cluster assembly protein KIAJIJGH_00664 334390.LAF_1079 3.6e-216 757.3 Lactobacillaceae narK ko:K02575 ko00910,map00910 M00615 ko00000,ko00001,ko00002,ko02000 2.A.1.8 Bacteria 1TRS9@1239,3FCBS@33958,4HEBM@91061,COG2223@1,COG2223@2 NA|NA|NA P Major Facilitator Superfamily KIAJIJGH_00665 334390.LAF_1080 3.5e-196 690.6 Lactobacillaceae moaA 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09394 RC03420 ko00000,ko00001,ko01000 Bacteria 1TP89@1239,3F5T2@33958,4HAKQ@91061,COG2896@1,COG2896@2 NA|NA|NA H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate KIAJIJGH_00666 334390.LAF_1081 1.1e-34 152.1 Lactobacillaceae moaD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.12 ko:K03636,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09395 RC02507 ko00000,ko00001,ko01000 Bacteria 1U6CT@1239,3F7ME@33958,4IG4I@91061,COG1977@1,COG1977@2 NA|NA|NA H ThiS family KIAJIJGH_00667 334390.LAF_1082 2.2e-72 278.1 Lactobacillaceae moaE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 R09395 RC02507 ko00000,ko00001,ko01000 Bacteria 1V3V0@1239,3F6Q7@33958,4HGZD@91061,COG0314@1,COG0314@2 NA|NA|NA H MoaE protein KIAJIJGH_00668 334390.LAF_1083 6e-55 219.9 Lactobacillaceae Bacteria 1U6NW@1239,2BTTC@1,32P0X@2,3F87X@33958,4IGFU@91061 NA|NA|NA S Flavodoxin KIAJIJGH_00669 334390.LAF_1084 5.6e-170 603.6 Lactobacillaceae fecD ko:K02015 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 1TPX6@1239,3F4NR@33958,4HAUK@91061,COG0609@1,COG0609@2 NA|NA|NA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily KIAJIJGH_00670 334390.LAF_1085 2.2e-142 511.5 Lactobacillaceae fecE 3.6.3.34 ko:K02013,ko:K09817 ko02010,map02010 M00240,M00242 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14,3.A.1.15.3,3.A.1.15.5 Bacteria 1UYT8@1239,3FC3C@33958,4HE1M@91061,COG1120@1,COG1120@2 NA|NA|NA HP AAA domain, putative AbiEii toxin, Type IV TA system KIAJIJGH_00671 334390.LAF_1086 7.2e-228 796.2 Lactobacillaceae ndh GO:0003674,GO:0003824,GO:0003955,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114 1.6.99.3 ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 1TR6X@1239,3F4N1@33958,4HA14@91061,COG1252@1,COG1252@2 NA|NA|NA C NADH dehydrogenase KIAJIJGH_00672 334390.LAF_1087 8e-54 216.1 Lactobacillaceae yitW ko:K02612 ko00360,ko01120,map00360,map01120 R09838 RC02690 ko00000,ko00001 Bacteria 1V9YV@1239,3F7D5@33958,4HKC6@91061,COG2151@1,COG2151@2 NA|NA|NA S Iron-sulfur cluster assembly protein KIAJIJGH_00673 1423815.BACR01000043_gene2099 1e-18 99.0 Lactobacillaceae M1-755 ko:K09155 ko00000 Bacteria 1VIMF@1239,3F8S3@33958,4HQ0V@91061,COG2461@1,COG2461@2 NA|NA|NA S Domain of unknown function (DUF1858) KIAJIJGH_00674 334390.LAF_1088 4.4e-255 886.7 Lactobacillaceae XK27_04775 ko:K09155 ko00000 Bacteria 1TRD5@1239,3F45M@33958,4HAAW@91061,COG2461@1,COG2461@2 NA|NA|NA S PAS domain KIAJIJGH_00675 543734.LCABL_30050 0.0 1085.1 Lactobacillaceae cadA Bacteria 1TQ07@1239,3F4JI@33958,4H9SP@91061,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase KIAJIJGH_00676 543734.LCABL_21380 2.1e-138 498.4 Bacilli ko:K07497 ko00000 Bacteria 1TU21@1239,4HDK4@91061,COG2801@1,COG2801@2 NA|NA|NA L COG2801 Transposase and inactivated derivatives KIAJIJGH_00677 543734.LCABL_21370 3.3e-43 180.6 Lactobacillaceae ko:K07483 ko00000 Bacteria 1U7MM@1239,3F9WU@33958,4IHIT@91061,COG2963@1,COG2963@2 NA|NA|NA L Transposase KIAJIJGH_00678 1423807.BACO01000023_gene708 5e-18 97.1 Lactobacillaceae lmrB Bacteria 1TPRN@1239,3F4A2@33958,4H9VV@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily KIAJIJGH_00680 334390.LAF_0917 4.6e-244 850.1 Lactobacillaceae yhjX GO:0005575,GO:0005623,GO:0005886,GO:0007154,GO:0008150,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0031667,GO:0031668,GO:0031669,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071944 ko:K08177 ko00000,ko02000 2.A.1.11 Bacteria 1TPR9@1239,3F4XT@33958,4HB93@91061,COG2223@1,COG2223@2 NA|NA|NA P Major Facilitator Superfamily KIAJIJGH_00681 334390.LAF_0916 1.7e-117 428.7 Lactobacillaceae ko:K07150 ko00000 Bacteria 1U5PM@1239,3F56J@33958,4HEHT@91061,COG1811@1,COG1811@2 NA|NA|NA S Protein of unknown function (DUF554) KIAJIJGH_00682 334390.LAF_0915 9e-256 889.0 Lactobacillaceae rarA ko:K07478 ko00000 Bacteria 1TPVV@1239,3F3NB@33958,4HAIS@91061,COG2256@1,COG2256@2 NA|NA|NA L recombination factor protein RarA KIAJIJGH_00684 334390.LAF_0913 0.0 1153.7 Lactobacillaceae oppD ko:K02031,ko:K02032 ko02024,map02024 M00239 ko00000,ko00001,ko00002,ko02000 3.A.1.5 Bacteria 1TS8Q@1239,3F4T6@33958,4HCZ1@91061,COG0444@1,COG0444@2 NA|NA|NA EP Psort location Cytoplasmic, score KIAJIJGH_00685 334390.LAF_0912 8e-243 845.9 Lactobacillaceae codA 3.5.4.1 ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 R00974,R01411,R02922 RC00074,RC00514,RC00809 ko00000,ko00001,ko01000 Bacteria 1TRK2@1239,3F4JP@33958,4HAAV@91061,COG0402@1,COG0402@2 NA|NA|NA F cytosine deaminase KIAJIJGH_00686 334390.LAF_0911 8e-244 849.4 Lactobacillaceae Bacteria 1TTBN@1239,3F4YG@33958,4HA3B@91061,COG1457@1,COG1457@2 NA|NA|NA U Belongs to the purine-cytosine permease (2.A.39) family KIAJIJGH_00687 334390.LAF_0909 1e-91 343.6 Lactobacillaceae ywnH GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 Bacteria 1V3V3@1239,3F70T@33958,4HHNY@91061,COG1247@1,COG1247@2 NA|NA|NA M Acetyltransferase (GNAT) domain KIAJIJGH_00688 334390.LAF_0908 3.4e-76 290.8 Lactobacillaceae msrB 1.8.4.11,1.8.4.12 ko:K07305,ko:K12267 ko00000,ko01000 Bacteria 1UPN0@1239,3F6H4@33958,4HGWN@91061,COG0229@1,COG0229@2 NA|NA|NA O peptide methionine sulfoxide reductase KIAJIJGH_00689 334390.LAF_0907 6.8e-71 273.1 Lactobacillaceae yqkB Bacteria 1VK6M@1239,3F7JD@33958,4HRFS@91061,COG4918@1,COG4918@2 NA|NA|NA S Belongs to the HesB IscA family KIAJIJGH_00690 334390.LAF_0906 3.6e-171 607.4 Lactobacillaceae ppaC GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464 3.6.1.1 ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Bacteria 1TPH6@1239,3F3PJ@33958,4H9T8@91061,COG1227@1,COG1227@2 NA|NA|NA C inorganic pyrophosphatase KIAJIJGH_00691 334390.LAF_0905 5.2e-95 353.6 Lactobacillaceae ko:K08996 ko00000 Bacteria 1VX0K@1239,3F6A5@33958,4HX2R@91061,COG3477@1,COG3477@2 NA|NA|NA S Protein of unknown function (DUF1440) KIAJIJGH_00692 334390.LAF_0904 0.0 1589.3 Lactobacillaceae parC GO:0005575,GO:0005622,GO:0005623,GO:0009330,GO:0032991,GO:0044424,GO:0044464 5.99.1.3 ko:K02469,ko:K02621 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1TRE7@1239,3F3MJ@33958,4HAQB@91061,COG0188@1,COG0188@2 NA|NA|NA L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule KIAJIJGH_00693 334390.LAF_0903 0.0 1258.8 Lactobacillaceae parE GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034335,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 ko:K02470,ko:K02622 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1TQCF@1239,3F430@33958,4H9UC@91061,COG0187@1,COG0187@2 NA|NA|NA L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule KIAJIJGH_00694 334390.LAF_0902 6.2e-103 380.2 Lactobacillaceae plsY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15,3.5.1.104 ko:K08591,ko:K22278 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1VA3J@1239,3FCBC@33958,4HHUW@91061,COG0344@1,COG0344@2 NA|NA|NA I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP KIAJIJGH_00695 334390.LAF_0901 4e-172 610.5 Lactobacillaceae lacX 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 Bacteria 1U26T@1239,3F3KT@33958,4HA4J@91061,COG2017@1,COG2017@2 NA|NA|NA G Aldose 1-epimerase KIAJIJGH_00696 334390.LAF_0900 1.6e-154 552.0 Bacteria Bacteria COG4973@1,COG4973@2 NA|NA|NA D DNA integration KIAJIJGH_00697 334390.LAF_0899 0.0 1342.0 Lactobacillaceae topA 5.99.1.2 ko:K03168 ko00000,ko01000,ko03032,ko03400 Bacteria 1TPUS@1239,3F3VS@33958,4HA6C@91061,COG0550@1,COG0550@2 NA|NA|NA L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone KIAJIJGH_00698 334390.LAF_0898 4.5e-152 543.9 Lactobacillaceae dprA GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 ko:K04096 ko00000 Bacteria 1TPP7@1239,3F41U@33958,4HGWM@91061,COG0758@1,COG0758@2 NA|NA|NA LU DNA protecting protein DprA KIAJIJGH_00699 334390.LAF_0897 1e-139 502.7 Lactobacillaceae rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1V1D6@1239,3F3JC@33958,4HB7M@91061,COG0164@1,COG0164@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids KIAJIJGH_00700 334390.LAF_0896 1.4e-161 575.5 Lactobacillaceae ylqF GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840 ko:K14540 ko00000,ko03009 Bacteria 1TQGK@1239,3F3MI@33958,4HA4D@91061,COG1161@1,COG1161@2 NA|NA|NA S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity KIAJIJGH_00701 334390.LAF_0895 3.1e-36 157.1 Lactobacillaceae yozE Bacteria 1VFI4@1239,3FCDP@33958,4HR7P@91061,COG4479@1,COG4479@2 NA|NA|NA S Belongs to the UPF0346 family KIAJIJGH_00702 334390.LAF_0894 7.1e-104 383.3 Lactobacillaceae ypmS Bacteria 1VF0K@1239,3F5K5@33958,4HIYN@91061,COG4698@1,COG4698@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2140) KIAJIJGH_00703 334390.LAF_0893 4.1e-167 594.0 Lactobacillaceae ypmR GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0016298,GO:0016787,GO:0016788,GO:0052689 Bacteria 1V76B@1239,3FBFD@33958,4HGIN@91061,COG2755@1,COG2755@2 NA|NA|NA E lipolytic protein G-D-S-L family KIAJIJGH_00704 334390.LAF_0892 7.1e-96 356.7 Lactobacillaceae cat ko:K18234 ko00000,ko01000,ko01504 Bacteria 1TPKX@1239,3F4PX@33958,4HF6J@91061,COG0110@1,COG0110@2 NA|NA|NA S Bacterial transferase hexapeptide (six repeats) KIAJIJGH_00705 334390.LAF_0891 2.6e-219 767.7 Lactobacillaceae 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1VTK3@1239,3F4XV@33958,4HUCI@91061,COG0111@1,COG0111@2 NA|NA|NA EH D-isomer specific 2-hydroxyacid dehydrogenase KIAJIJGH_00706 334390.LAF_0890 1.8e-153 548.5 Lactobacillaceae DegV Bacteria 1TRZ4@1239,3F4CW@33958,4HBR8@91061,COG1307@1,COG1307@2 NA|NA|NA S EDD domain protein, DegV family KIAJIJGH_00707 334390.LAF_0889 1.2e-109 402.5 Lactobacillaceae hlyIII ko:K11068 ko00000,ko02042 Bacteria 1TSFK@1239,3F578@33958,4HAT2@91061,COG1272@1,COG1272@2 NA|NA|NA S protein, hemolysin III KIAJIJGH_00708 334390.LAF_0888 8.7e-95 352.8 Lactobacillaceae folA GO:0000166,GO:0003674,GO:0003824,GO:0004146,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070401,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv2763c Bacteria 1VB80@1239,3F6Y4@33958,4HIGJ@91061,COG0262@1,COG0262@2 NA|NA|NA H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis KIAJIJGH_00709 334390.LAF_0887 6.8e-189 666.4 Lactobacillaceae thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSIR@1239,3F3SB@33958,4H9QS@91061,COG0207@1,COG0207@2 NA|NA|NA F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis KIAJIJGH_00710 334390.LAF_0886 0.0 1192.2 Lactobacillaceae yfmR ko:K15738 ko00000,ko02000 3.A.1.120.6 Bacteria 1TPAX@1239,3FC7W@33958,4H9TK@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter, ATP-binding protein KIAJIJGH_00711 334390.LAF_0885 1.2e-222 778.9 Lactobacillaceae cca 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 Bacteria 1TQ2A@1239,3F3VH@33958,4HB2W@91061,COG0617@1,COG0617@2 NA|NA|NA J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate KIAJIJGH_00712 334390.LAF_0884 4.7e-165 587.0 Lactobacillaceae xerD ko:K04763 ko00000,ko03036 Bacteria 1UFH8@1239,3F3KV@33958,4IES1@91061,COG4974@1,COG4974@2 NA|NA|NA L Phage integrase, N-terminal SAM-like domain KIAJIJGH_00713 334390.LAF_0883 1.8e-234 818.1 Lactobacillaceae Bacteria 1TT97@1239,3F3ND@33958,4HAIA@91061,COG0457@1,COG0457@2 NA|NA|NA S Tetratricopeptide repeat protein KIAJIJGH_00714 334390.LAF_0882 4.4e-40 170.2 Lactobacillaceae hup ko:K03530 ko00000,ko03032,ko03036,ko03400 Bacteria 1V9XQ@1239,3F6YN@33958,4HKF2@91061,COG0776@1,COG0776@2 NA|NA|NA L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions KIAJIJGH_00715 334390.LAF_0881 9.7e-247 859.0 Lactobacillaceae der GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.399,1.1.1.95 ko:K00058,ko:K03977 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko03009,ko04147 Bacteria 1TPNM@1239,3F4V0@33958,4HAJ6@91061,COG1160@1,COG1160@2 NA|NA|NA S GTPase that plays an essential role in the late steps of ribosome biogenesis KIAJIJGH_00716 334390.LAF_0880 5.8e-209 733.4 Lactobacillaceae rpsA 1.17.7.4 ko:K02945,ko:K03527 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 M00096,M00178 R05884,R08210 RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 Bacteria 1TQ9N@1239,3F4DQ@33958,4H9PX@91061,COG0539@1,COG0539@2 NA|NA|NA J Ribosomal protein S1 KIAJIJGH_00717 334390.LAF_0879 2e-118 431.8 Lactobacillaceae cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.17.7.4,2.5.1.19,2.7.1.26,2.7.4.25,2.7.7.2,6.3.2.1 ko:K00800,ko:K00945,ko:K02945,ko:K03527,ko:K03977,ko:K11753,ko:K13799 ko00240,ko00400,ko00410,ko00740,ko00770,ko00900,ko01100,ko01110,ko01130,ko01230,ko03010,map00240,map00400,map00410,map00740,map00770,map00900,map01100,map01110,map01130,map01230,map03010 M00022,M00052,M00096,M00119,M00125,M00178 R00158,R00161,R00512,R00549,R01665,R02473,R03460,R05884,R08210 RC00002,RC00017,RC00096,RC00141,RC00350,RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03009,ko03011 iPC815.YPO1391,iSDY_1059.SDY_2348 Bacteria 1V3IA@1239,3F3W4@33958,4HFZE@91061,COG0283@1,COG0283@2 NA|NA|NA F Belongs to the cytidylate kinase family. Type 1 subfamily KIAJIJGH_00718 334390.LAF_0878 9.7e-31 140.2 Lactobacillaceae Bacteria 1VFEU@1239,3F6WV@33958,4HNW5@91061,COG1388@1,COG1388@2 NA|NA|NA M Lysin motif KIAJIJGH_00719 334390.LAF_0877 3.1e-278 963.8 Lactobacillaceae recQ1 3.6.4.12 ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPN5@1239,3F4PY@33958,4H9QP@91061,COG0514@1,COG0514@2 NA|NA|NA L ATP-dependent DNA helicase RecQ KIAJIJGH_00720 334390.LAF_0876 6e-199 699.9 Lactobacillaceae ypbB 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQU9@1239,3F45N@33958,4HJ71@91061,COG4955@1,COG4955@2 NA|NA|NA S Helix-turn-helix domain KIAJIJGH_00721 334390.LAF_0875 1.1e-80 306.2 Lactobacillaceae Bacteria 1V4BW@1239,3F4HD@33958,4HHFT@91061,COG3601@1,COG3601@2 NA|NA|NA U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins KIAJIJGH_00722 334390.LAF_0874 2.8e-131 474.6 Lactobacillaceae rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.21,5.4.99.22 ko:K06178,ko:K06182,ko:K06183 ko00000,ko01000,ko03009 Bacteria 1TP68@1239,3F402@33958,4H9MU@91061,COG1187@1,COG1187@2 NA|NA|NA J Belongs to the pseudouridine synthase RsuA family KIAJIJGH_00723 334390.LAF_0873 2.5e-101 374.8 Lactobacillaceae scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K06024 ko00000,ko03036 Bacteria 1V6HI@1239,3F5RN@33958,4HIQ0@91061,COG1386@1,COG1386@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves KIAJIJGH_00724 334390.LAF_0872 1.3e-140 505.8 Lactobacillaceae scpA GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K05896 ko00000,ko03036 Bacteria 1TRW3@1239,3F4FS@33958,4HA6Q@91061,COG1354@1,COG1354@2 NA|NA|NA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves KIAJIJGH_00725 334390.LAF_0871 3.4e-67 260.8 Lactobacillaceae ribT ko:K02859 ko00000 Bacteria 1VAD7@1239,3F7QC@33958,4HKR2@91061,COG0454@1,COG0456@2 NA|NA|NA K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases KIAJIJGH_00726 334390.LAF_0870 6e-160 570.1 Lactobacillaceae xerD ko:K04763 ko00000,ko03036 Bacteria 1TQRG@1239,3F3V9@33958,4HAEX@91061,COG4974@1,COG4974@2 NA|NA|NA D recombinase XerD KIAJIJGH_00727 334390.LAF_0869 1.6e-168 598.6 Lactobacillaceae cvfB ko:K00243 ko00000 Bacteria 1TQ1Z@1239,3F44W@33958,4HDAZ@91061,COG2996@1,COG2996@2 NA|NA|NA S S1 domain KIAJIJGH_00728 334390.LAF_0868 2.4e-267 927.5 Lactobacillaceae pyk GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009986,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0022607,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40,2.7.7.4 ko:K00873,ko:K00958 ko00010,ko00230,ko00261,ko00450,ko00620,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00261,map00450,map00620,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050,M00176,M00596 R00200,R00430,R00529,R01138,R01858,R02320,R04929 RC00002,RC00015,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 iECO103_1326.ECO103_1819,iPC815.YPO2393 Bacteria 1TPGG@1239,3F3JU@33958,4H9VY@91061,COG0469@1,COG0469@2 NA|NA|NA G Belongs to the pyruvate kinase family KIAJIJGH_00729 334390.LAF_0867 0.0 2139.0 Lactobacillaceae dnaE 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TPYG@1239,3F4AM@33958,4H9T3@91061,COG0587@1,COG0587@2 NA|NA|NA L DNA polymerase KIAJIJGH_00731 334390.LAF_0865 6.6e-237 826.2 Lactobacillaceae pepT GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0034701,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045148,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.4 ko:K01258 ko00000,ko01000,ko01002 Bacteria 1TP3A@1239,3F45V@33958,4HAZE@91061,COG2195@1,COG2195@2 NA|NA|NA E Cleaves the N-terminal amino acid of tripeptides KIAJIJGH_00732 334390.LAF_0864 1.7e-156 558.5 Lactobacillaceae yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.4.16 ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ27@1239,3F3ZD@33958,4H9NY@91061,COG0327@1,COG0327@2 NA|NA|NA S Belongs to the GTP cyclohydrolase I type 2 NIF3 family KIAJIJGH_00733 334390.LAF_0863 1.2e-126 459.1 Lactobacillaceae trmK GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.217 ko:K06967 ko00000,ko01000,ko03016 Bacteria 1V3I4@1239,3F4GT@33958,4HHIM@91061,COG2384@1,COG2384@2 NA|NA|NA S SAM-dependent methyltransferase KIAJIJGH_00734 334390.LAF_0862 2.8e-117 427.9 Lactobacillaceae ktrA ko:K03499 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1TQ9H@1239,3F5G0@33958,4HBPH@91061,COG0569@1,COG0569@2 NA|NA|NA P domain protein KIAJIJGH_00735 334390.LAF_0861 6.7e-227 793.1 Lactobacillaceae ktrB ko:K03498 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1TQ4S@1239,3F5BE@33958,4H9ME@91061,COG0168@1,COG0168@2 NA|NA|NA P Potassium uptake protein KIAJIJGH_00736 334390.LAF_0860 9.6e-197 692.6 Lactobacillaceae asd 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPC6@1239,3F4S9@33958,4HA9H@91061,COG0136@1,COG0136@2 NA|NA|NA E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate KIAJIJGH_00737 334390.LAF_0859 6.5e-218 763.1 Lactobacillaceae patA 2.6.1.1 ko:K00812,ko:K00841,ko:K10907 ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00525 R00355,R00694,R00734,R00896,R02433,R02619,R04467,R05052 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP0J@1239,3F3MX@33958,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase KIAJIJGH_00738 334390.LAF_0858 2.8e-140 504.6 Lactobacillaceae dapB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0070402,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 iJN678.dapB,iNJ661.Rv2773c,iYO844.BSU22490 Bacteria 1TR9D@1239,3F3MA@33958,4HA5X@91061,COG0289@1,COG0289@2 NA|NA|NA E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate KIAJIJGH_00739 334390.LAF_0857 9.2e-175 619.4 Lactobacillaceae dapA 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCK@1239,3F4UH@33958,4H9K9@91061,COG0329@1,COG0329@2 NA|NA|NA E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) KIAJIJGH_00740 334390.LAF_0856 1.8e-220 771.5 Lactobacillaceae hipO GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.47 ko:K05823,ko:K21613 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TPD7@1239,3F419@33958,4H9SG@91061,COG1473@1,COG1473@2 NA|NA|NA E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate KIAJIJGH_00741 334390.LAF_0855 6.6e-72 277.3 Lactobacillaceae dapD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117,2.3.1.89 ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 M00016,M00525 R04364,R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 iSbBS512_1146.SbBS512_E0158,iYO844.BSU14180 Bacteria 1TQUJ@1239,3F3U0@33958,4H9KY@91061,COG2171@1,COG2171@2 NA|NA|NA E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate KIAJIJGH_00742 334390.LAF_0854 2.4e-253 880.9 Lactobacillaceae lysA 4.1.1.19,4.1.1.20 ko:K01585,ko:K01586 ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map00330,map01100,map01110,map01120,map01130,map01230 M00016,M00133,M00525,M00526,M00527 R00451,R00566 RC00299 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS18870 Bacteria 1TPE9@1239,3F3VJ@33958,4H9XW@91061,COG0019@1,COG0019@2 NA|NA|NA E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine KIAJIJGH_00743 334390.LAF_0853 7.7e-263 912.5 Lactobacillaceae lysC GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iYO844.BSU03790 Bacteria 1TPQJ@1239,3F48V@33958,4HAEP@91061,COG0527@1,COG0527@2 NA|NA|NA E Belongs to the aspartokinase family KIAJIJGH_00744 334390.LAF_0852 3.3e-178 630.9 Lactobacillaceae dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPMN@1239,3F4F7@33958,4HBH4@91061,COG0253@1,COG0253@2 NA|NA|NA E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan KIAJIJGH_00745 334390.LAF_0851 1.6e-168 598.6 Lactobacillaceae apbE 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria 1TR9C@1239,3F3QR@33958,4HHVC@91061,COG1477@1,COG1477@2 NA|NA|NA H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein KIAJIJGH_00746 1293597.BN147_05685 5.8e-65 254.2 Lactobacillaceae ko:K18926 M00715 ko00000,ko00002,ko02000 2.A.1.3.30 Bacteria 1UYQB@1239,3F3NG@33958,4HE3Y@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily KIAJIJGH_00747 1293597.BN147_05685 1.3e-25 122.5 Lactobacillaceae ko:K18926 M00715 ko00000,ko00002,ko02000 2.A.1.3.30 Bacteria 1UYQB@1239,3F3NG@33958,4HE3Y@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily KIAJIJGH_00748 1280668.ATVT01000003_gene2611 7.4e-92 343.6 Butyrivibrio Bacteria 1UDID@1239,24CJT@186801,4BYIX@830,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase KIAJIJGH_00749 334390.LAF_0845 3.8e-207 727.2 Lactobacillaceae sigA GO:0000988,GO:0000990,GO:0001098,GO:0001101,GO:0001108,GO:0001666,GO:0002791,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0016020,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032879,GO:0032880,GO:0036293,GO:0040007,GO:0042221,GO:0043175,GO:0043254,GO:0044087,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051173,GO:0051223,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070063,GO:0070201,GO:0070482,GO:0071944,GO:0080090,GO:0090087,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:1903530,GO:2000112,GO:2000142,GO:2001141 ko:K03086,ko:K03087 ko02026,ko05111,map02026,map05111 ko00000,ko00001,ko03021 Bacteria 1TPD6@1239,3F4CF@33958,4HB1H@91061,COG0568@1,COG0568@2 NA|NA|NA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth KIAJIJGH_00750 334390.LAF_0844 0.0 1226.8 Lactobacillaceae dnaG ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1TQ0X@1239,3F3N1@33958,4HAG2@91061,COG0358@1,COG0358@2 NA|NA|NA L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication KIAJIJGH_00751 334390.LAF_0843 0.0 1357.0 Lactobacillaceae glyS GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 ko:K01879,ko:K14164 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAPECO1_1312.APECO1_2891,iE2348C_1286.E2348C_3810,iECABU_c1320.ECABU_c40010,iECED1_1282.ECED1_4242,iECH74115_1262.ECH74115_4934,iECNA114_1301.ECNA114_3710,iECOK1_1307.ECOK1_4005,iECP_1309.ECP_3661,iECS88_1305.ECS88_3976,iECSF_1327.ECSF_3393,iECSP_1301.ECSP_4554,iECs_1301.ECs4442,iG2583_1286.G2583_4300,iJN678.glyS,iUMN146_1321.UM146_17960,iUTI89_1310.UTI89_C4099,ic_1306.c4378 Bacteria 1TNZ7@1239,3F4G8@33958,4H9NT@91061,COG0751@1,COG0751@2 NA|NA|NA J Glycyl-tRNA synthetase beta subunit KIAJIJGH_00752 334390.LAF_0842 4.9e-187 660.2 Lactobacillaceae glyQ GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016875,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 ko:K01878,ko:K14164 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF1260.b3560,iAF987.Gmet_2942,iJO1366.b3560,iPC815.YPO4072,iY75_1357.Y75_RS19360 Bacteria 1TPW8@1239,3F3T8@33958,4HBCF@91061,COG0752@1,COG0752@2 NA|NA|NA J glycyl-tRNA synthetase alpha subunit KIAJIJGH_00753 334390.LAF_0841 2.9e-156 557.8 Lactobacillaceae recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1UZ19@1239,3F56P@33958,4HAHI@91061,COG1381@1,COG1381@2 NA|NA|NA L Involved in DNA repair and RecF pathway recombination KIAJIJGH_00754 334390.LAF_0840 8.7e-170 602.8 Lactobacillaceae era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 ko:K03595,ko:K06883 ko00000,ko03009,ko03029 Bacteria 1TP3R@1239,3F3WQ@33958,4H9WF@91061,COG1159@1,COG1159@2 NA|NA|NA S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism KIAJIJGH_00755 334390.LAF_0839 1e-66 259.2 Lactobacillaceae dgkA 2.7.1.107,2.7.1.66 ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 R02240,R05626 RC00002,RC00017 ko00000,ko00001,ko01000 iAF987.Gmet_2369,iSB619.SA_RS07900 Bacteria 1VEGR@1239,3F7DC@33958,4HNKN@91061,COG0818@1,COG0818@2 NA|NA|NA M Diacylglycerol kinase KIAJIJGH_00756 334390.LAF_0838 1.1e-80 305.8 Lactobacillaceae ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 ko:K01489,ko:K03474,ko:K03595,ko:K07042 ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100 M00124 R01878,R02485,R05838,R08221 RC00074,RC00514,RC01476 ko00000,ko00001,ko00002,ko01000,ko03009,ko03029 Bacteria 1V6BU@1239,3F516@33958,4HIIE@91061,COG0319@1,COG0319@2 NA|NA|NA S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA KIAJIJGH_00757 334390.LAF_0837 2.9e-179 634.4 Lactobacillaceae phoH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06217 ko00000 Bacteria 1TP35@1239,3F4E7@33958,4HBD5@91061,COG1702@1,COG1702@2 NA|NA|NA T phosphate starvation-inducible protein PhoH KIAJIJGH_00758 334390.LAF_0836 4.6e-71 273.9 Lactobacillaceae yqeY ko:K09117 ko00000 Bacteria 1V6F2@1239,3F6I0@33958,4HIQP@91061,COG1610@1,COG1610@2 NA|NA|NA S YqeY-like protein KIAJIJGH_00759 334390.LAF_0835 5.7e-23 112.8 Lactobacillaceae rpsU GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02970 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEHU@1239,3F81Y@33958,4HNPV@91061,COG0828@1,COG0828@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS21 family KIAJIJGH_00760 334390.LAF_0834 5.1e-130 470.3 Lactobacillaceae yfeJ 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1UAH0@1239,3F4AV@33958,4HHTX@91061,COG0518@1,COG0518@2 NA|NA|NA F glutamine amidotransferase KIAJIJGH_00761 334390.LAF_0833 0.0 1186.0 Lactobacillaceae aspS 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TPCN@1239,3F4PE@33958,4HACD@91061,COG0173@1,COG0173@2 NA|NA|NA J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) KIAJIJGH_00762 334390.LAF_0832 1e-248 865.5 Lactobacillaceae hisS 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP3D@1239,3F3M3@33958,4HAM2@91061,COG0124@1,COG0124@2 NA|NA|NA J histidyl-tRNA synthetase KIAJIJGH_00763 334390.LAF_0831 2.1e-196 691.4 Lactobacillaceae 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 Bacteria 1TQ5U@1239,3F4PZ@33958,4HVEG@91061,COG0095@1,COG0095@2 NA|NA|NA H Lipoate-protein ligase KIAJIJGH_00764 334390.LAF_0830 1.6e-174 618.6 Lactobacillaceae lytH GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Bacteria 1TQ74@1239,3FC12@33958,4HAV3@91061,COG0860@1,COG0860@2 NA|NA|NA M Ami_3 KIAJIJGH_00765 334390.LAF_0829 6.8e-169 599.7 Lactobacillaceae yniA GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 Bacteria 1U79A@1239,3F3RK@33958,4HAZS@91061,COG3001@1,COG3001@2 NA|NA|NA G Phosphotransferase enzyme family KIAJIJGH_00766 334390.LAF_0828 4.6e-174 617.1 Lactobacillaceae mmuM GO:0003674,GO:0003824,GO:0005488,GO:0006575,GO:0006790,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008270,GO:0008757,GO:0008898,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033477,GO:0033554,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:1901564 1.5.1.20,2.1.1.10 ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 M00377 R00650,R01224,R07168 RC00003,RC00035,RC00081 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHQ5@1239,3F4UT@33958,4HAS6@91061,COG2040@1,COG2040@2 NA|NA|NA H homocysteine S-methyltransferase KIAJIJGH_00767 334390.LAF_0827 2.3e-246 857.8 Lactobacillaceae mmuP GO:0000096,GO:0000097,GO:0000100,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0015806,GO:0016020,GO:0016053,GO:0019752,GO:0022857,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682 ko:K02205,ko:K03293,ko:K11733,ko:K16235,ko:K16236 ko00000,ko02000 2.A.3.1,2.A.3.1.10,2.A.3.1.2 Bacteria 1UHNR@1239,3F4BG@33958,4HUT7@91061,COG0833@1,COG0833@2 NA|NA|NA E amino acid KIAJIJGH_00768 334390.LAF_0826 2.2e-159 568.2 Lactobacillaceae metAA GO:0003674,GO:0003824,GO:0008374,GO:0008899,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS11970 Bacteria 1TQVR@1239,3F5CA@33958,4H9W4@91061,COG1897@1,COG1897@2 NA|NA|NA E Transfers an acetyl group from acetyl-CoA to KIAJIJGH_00769 334390.LAF_0825 2.8e-213 747.7 Lactobacillaceae hom1 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ2H@1239,3F3KS@33958,4HBAP@91061,COG0460@1,COG0460@2 NA|NA|NA E Homoserine dehydrogenase KIAJIJGH_00770 334390.LAF_0824 1.5e-135 488.8 Lactobacillaceae Bacteria 1TR1J@1239,3FC9P@33958,4HHQ8@91061,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain KIAJIJGH_00771 334390.LAF_0823 3.1e-153 547.7 Lactobacillaceae cjaA ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TT11@1239,3F54P@33958,4HFBQ@91061,COG0834@1,COG0834@2 NA|NA|NA ET ABC transporter substrate-binding protein KIAJIJGH_00772 334390.LAF_0822 3.9e-136 490.7 Lactobacillaceae glnQ 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1TNYD@1239,3FC3P@33958,4HDK7@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein KIAJIJGH_00773 334390.LAF_0821 5.7e-94 350.5 Lactobacillaceae ko:K02029 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TR7R@1239,3F45E@33958,4HGVA@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter permease KIAJIJGH_00774 334390.LAF_0820 9.3e-113 412.9 Lactobacillaceae papP ko:K02029 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TRU3@1239,3F3XD@33958,4HGE1@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter, permease protein KIAJIJGH_00776 797515.HMPREF9103_00534 6.7e-91 341.3 Lactobacillaceae yxeQ GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0047547,GO:0071704 Bacteria 1TSD7@1239,3F5NR@33958,4IF57@91061,COG2079@1,COG2079@2 NA|NA|NA S MmgE/PrpD family KIAJIJGH_00777 797515.HMPREF9103_00528 1.1e-171 609.8 Lactobacillaceae pcaB 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPMM@1239,3F5ZH@33958,4HDVU@91061,COG0015@1,COG0015@2 NA|NA|NA F Adenylosuccinate lyase C-terminus KIAJIJGH_00778 203120.LEUM_0113 1.7e-146 525.8 Leuconostocaceae 3.5.1.47 ko:K01436,ko:K05823,ko:K21613 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TPD7@1239,4AXIY@81850,4H9WQ@91061,COG1473@1,COG1473@2 NA|NA|NA E Peptidase dimerisation domain KIAJIJGH_00779 1423806.JCM15457_2517 5.6e-87 327.4 Lactobacillaceae yxeO 3.6.3.21 ko:K02028,ko:K10008,ko:K16960,ko:K16963 ko02010,map02010 M00233,M00236,M00585,M00586 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.13,3.A.1.3.9 Bacteria 1TNYD@1239,3F97V@33958,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E ATPases associated with a variety of cellular activities KIAJIJGH_00780 1423806.JCM15457_2516 1.7e-70 272.7 Lactobacillaceae yxeN GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 ko:K16961,ko:K16962 ko02010,map02010 M00586 ko00000,ko00001,ko00002,ko02000 3.A.1.3 Bacteria 1UZ2C@1239,3F7IY@33958,4HF77@91061,COG0765@1,COG0765@2 NA|NA|NA U ABC transporter, permease protein KIAJIJGH_00781 203120.LEUM_0109 1.3e-46 193.0 Bacilli yxeL ko:K00680 ko00000,ko01000 Bacteria 1V9FA@1239,4HJ4W@91061,COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase KIAJIJGH_00782 1423734.JCM14202_3202 3.1e-67 261.9 Lactobacillaceae yxeM ko:K16961 ko02010,map02010 M00586 ko00000,ko00001,ko00002,ko02000 3.A.1.3 Bacteria 1TR13@1239,3F77M@33958,4HDQ8@91061,COG0834@1,COG0834@2 NA|NA|NA ET Bacterial periplasmic substrate-binding proteins KIAJIJGH_00784 334390.LAF_0815 2.8e-210 737.6 Lactobacillaceae metB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 2.5.1.48,4.4.1.8 ko:K01739,ko:K01760 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPC7@1239,3F4CK@33958,4HAFQ@91061,COG0626@1,COG0626@2 NA|NA|NA E Cys/Met metabolism PLP-dependent enzyme KIAJIJGH_00785 334390.LAF_0814 5.6e-217 760.0 Lactobacillaceae metC1 2.5.1.48,4.4.1.8 ko:K01739,ko:K01760 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPC7@1239,3F3Y2@33958,4HAFQ@91061,COG0626@1,COG0626@2 NA|NA|NA E cystathionine KIAJIJGH_00786 334390.LAF_0813 3.5e-85 320.9 Lactobacillaceae slyA Bacteria 1W4X8@1239,3F8CB@33958,4I172@91061,COG1846@1,COG1846@2 NA|NA|NA K Transcriptional regulator KIAJIJGH_00787 334390.LAF_0812 2.4e-77 294.7 Lactobacillaceae dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360 ko:K07560 ko00000,ko01000,ko03016 Bacteria 1V6GH@1239,3F6GK@33958,4HINN@91061,COG1490@1,COG1490@2 NA|NA|NA J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality KIAJIJGH_00788 334390.LAF_0811 0.0 1478.4 Lactobacillaceae relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 R00429 RC00002,RC00078 ko00000,ko00001,ko01000 iHN637.CLJU_RS16615,iYO844.BSU27600 Bacteria 1TNYZ@1239,3F44F@33958,4HBX7@91061,COG0317@1,COG0317@2 NA|NA|NA KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance KIAJIJGH_00789 334390.LAF_0810 4.4e-58 230.3 Lactobacillaceae Bacteria 1U6RR@1239,2C2I6@1,30AJ5@2,3F8DM@33958,4IGJ7@91061 NA|NA|NA KIAJIJGH_00790 334390.LAF_0809 6.8e-136 490.0 Lactobacillaceae rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 ko00000,ko01000,ko03009 Bacteria 1V1CT@1239,3F64Z@33958,4HH8P@91061,COG1385@1,COG1385@2 NA|NA|NA J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit KIAJIJGH_00791 334390.LAF_0808 2e-177 628.2 Lactobacillaceae prmA ko:K02687 ko00000,ko01000,ko03009 Bacteria 1TPKI@1239,3F47Z@33958,4HAMF@91061,COG2264@1,COG2264@2 NA|NA|NA J Ribosomal protein L11 methyltransferase KIAJIJGH_00792 334390.LAF_0807 1.2e-54 218.8 Lactobacillaceae Bacteria 1W026@1239,2FCQV@1,344U2@2,3F7FM@33958,4HZ7F@91061 NA|NA|NA KIAJIJGH_00794 334390.LAF_0806 5.2e-173 613.6 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1TPSY@1239,3F3RM@33958,4HB0Z@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily. LDH family KIAJIJGH_00795 1069534.LRC_10300 1.6e-219 768.5 Lactobacillaceae ko:K07496 ko00000 Bacteria 1TT4J@1239,3F481@33958,4HEKB@91061,COG0675@1,COG0675@2 NA|NA|NA L Probable transposase KIAJIJGH_00796 334390.LAF_0805 4.7e-96 357.5 Lactobacillaceae Bacteria 1W76F@1239,3FAKF@33958,4II3P@91061,COG5542@1,COG5542@2 NA|NA|NA S integral membrane protein KIAJIJGH_00797 1114972.AUAW01000009_gene2156 1.1e-12 80.1 Bacilli aes Bacteria 1TRYT@1239,4HC3I@91061,COG0657@1,COG0657@2 NA|NA|NA I esterase lipase KIAJIJGH_00798 511437.Lbuc_1874 8.4e-37 160.6 Lactobacillaceae Bacteria 1W4NV@1239,28XJS@1,2ZJGW@2,3F6XN@33958,4I15N@91061 NA|NA|NA S CRISPR-associated protein (Cas_Csn2) KIAJIJGH_00799 1545701.LACWKB10_0720 4.9e-35 153.7 Lactobacillaceae cas2 ko:K09951 ko00000,ko02048 Bacteria 1VEH4@1239,3F7KD@33958,4HNYR@91061,COG3512@1,COG3512@2 NA|NA|NA L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette KIAJIJGH_00800 511437.Lbuc_1876 1.9e-92 345.9 Lactobacillaceae cas1 ko:K15342 ko00000,ko02048,ko03400 Bacteria 1TT0J@1239,3F3RW@33958,4HC5E@91061,COG1518@1,COG1518@2 NA|NA|NA L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette KIAJIJGH_00801 1423780.LOT_2161 0.0 1178.3 Lactobacillaceae cas9 ko:K09952 ko00000,ko01000,ko02048 Bacteria 1TPSD@1239,3F554@33958,4HE0R@91061,COG3513@1,COG3513@2 NA|NA|NA L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer KIAJIJGH_00802 334390.LAF_0804 0.0 1251.1 Lactobacillaceae Bacteria 1UYWB@1239,3F5AG@33958,4HTZD@91061,COG1807@1,COG1807@2 NA|NA|NA M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family KIAJIJGH_00803 525309.HMPREF0494_0059 1.8e-139 501.9 Lactobacillaceae thiM GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008972,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.50 ko:K00878 ko00730,ko01100,map00730,map01100 M00127 R04448 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V1R6@1239,3F43J@33958,4HFTJ@91061,COG2145@1,COG2145@2 NA|NA|NA H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) KIAJIJGH_00804 334390.LAF_0802 2.1e-143 515.0 Lactobacillaceae thiD GO:0008150,GO:0040007 2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17 ko:K00941,ko:K03147,ko:K21219 ko00730,ko01100,map00730,map01100 M00127 R03223,R03471,R03472,R04509,R10712 RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ4A@1239,3F3NA@33958,4HAAH@91061,COG0351@1,COG0351@2 NA|NA|NA H Phosphomethylpyrimidine kinase KIAJIJGH_00805 334390.LAF_0801 2.4e-113 414.8 Lactobacillaceae thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3ZR@1239,3F5ZQ@33958,4HH1E@91061,COG0352@1,COG0352@2 NA|NA|NA H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) KIAJIJGH_00806 334390.LAF_0800 1.5e-149 535.4 Lactobacillaceae thiD GO:0008150,GO:0040007 2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17 ko:K00941,ko:K03147,ko:K21219 ko00730,ko01100,map00730,map01100 M00127 R03223,R03471,R03472,R04509,R10712 RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ4A@1239,3F3NA@33958,4HAAH@91061,COG0351@1,COG0351@2 NA|NA|NA H Phosphomethylpyrimidine kinase KIAJIJGH_00807 334390.LAF_0799 1.2e-68 265.8 Lactobacillaceae psiE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K13256 ko00000 Bacteria 1VCG5@1239,3FBQN@33958,4HKQN@91061,COG3223@1,COG3223@2 NA|NA|NA S Phosphate-starvation-inducible E KIAJIJGH_00808 334390.LAF_0798 3.8e-38 163.7 Bacteria ko:K07052 ko00000 Bacteria COG1266@1,COG1266@2 NA|NA|NA V CAAX protease self-immunity KIAJIJGH_00809 1423806.JCM15457_2005 2.1e-215 755.0 Lactobacillaceae gltD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 iJN678.gltD,iNJ661.Rv3858c,iSB619.SA_RS02450 Bacteria 1TQ1A@1239,3FB6A@33958,4HAD5@91061,COG0493@1,COG0493@2 NA|NA|NA E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster KIAJIJGH_00810 1423806.JCM15457_2004 0.0 2376.7 Lactobacillaceae gltB GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1,2.1.1.21 ko:K00265,ko:K00284,ko:K22083 ko00250,ko00630,ko00680,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00680,map00910,map01100,map01110,map01120,map01130,map01230 R00021,R00093,R00114,R00248,R01586,R10086 RC00006,RC00010,RC00554,RC02799 ko00000,ko00001,ko01000 iBWG_1329.BWG_2914,iECDH10B_1368.ECDH10B_3387,iECDH1ME8569_1439.EcDH1_0495,iEcDH1_1363.EcDH1_0495,iPC815.YPO3557 Bacteria 1TQ0B@1239,3F4TU@33958,4HA4G@91061,COG0067@1,COG0067@2,COG0069@1,COG0069@2,COG0070@1,COG0070@2 NA|NA|NA E GXGXG motif KIAJIJGH_00811 334390.LAF_0797 7.6e-82 309.7 Lactobacillaceae 1.1.1.90 ko:K00055,ko:K06898 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 M00537,M00538 R01763,R02611,R04304,R05282,R05347,R05348 RC00087,RC00116 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP8E@1239,3F3QP@33958,4HAH9@91061,COG1062@1,COG1062@2 NA|NA|NA C Zn-dependent alcohol dehydrogenases, class III KIAJIJGH_00812 334390.LAF_0797 3.5e-101 374.4 Lactobacillaceae 1.1.1.90 ko:K00055,ko:K06898 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 M00537,M00538 R01763,R02611,R04304,R05282,R05347,R05348 RC00087,RC00116 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP8E@1239,3F3QP@33958,4HAH9@91061,COG1062@1,COG1062@2 NA|NA|NA C Zn-dependent alcohol dehydrogenases, class III KIAJIJGH_00813 387344.LVIS_0910 3.6e-09 67.4 Lactobacillaceae Bacteria 1V1MH@1239,3F527@33958,4HFVE@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain KIAJIJGH_00814 2074.JNYD01000015_gene4386 4.7e-09 67.0 Pseudonocardiales Bacteria 2GWHB@201174,4EB3C@85010,COG1917@1,COG1917@2 NA|NA|NA S ChrR Cupin-like domain KIAJIJGH_00815 334390.LAF_0794 3.9e-98 364.0 Lactobacillaceae msrA 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 ko00000,ko01000 Bacteria 1TQ3E@1239,3F3YI@33958,4HAIV@91061,COG0225@1,COG0225@2 NA|NA|NA O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine KIAJIJGH_00816 334390.LAF_0793 5.5e-158 563.5 Lactobacillaceae ko:K02073 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TQAS@1239,3F3WP@33958,4HCTA@91061,COG1464@1,COG1464@2 NA|NA|NA P Belongs to the nlpA lipoprotein family KIAJIJGH_00817 334390.LAF_0791 7.1e-103 379.8 Lactobacillaceae msrA 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 ko00000,ko01000 Bacteria 1TQ3E@1239,3F3YI@33958,4HAIV@91061,COG0225@1,COG0225@2 NA|NA|NA O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine KIAJIJGH_00818 334390.LAF_0790 3.2e-116 424.5 Lactobacillaceae ko:K07150 ko00000 Bacteria 1U5PM@1239,3F56J@33958,4HEHT@91061,COG1811@1,COG1811@2 NA|NA|NA S Protein of unknown function (DUF554) KIAJIJGH_00819 334390.LAF_0789 5.7e-101 373.6 Lactobacillaceae Bacteria 1TPQX@1239,3FB3W@33958,4HAME@91061,COG4300@1,COG4300@2 NA|NA|NA P Cadmium resistance transporter KIAJIJGH_00820 334390.LAF_1435 2.9e-190 671.0 Lactobacillaceae mocA ko:K22230 ko00562,ko01120,map00562,map01120 R09954 RC00182 ko00000,ko00001,ko01000 Bacteria 1TQSS@1239,3F4EV@33958,4HCIG@91061,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase KIAJIJGH_00821 334390.LAF_1436 1.9e-62 245.0 Lactobacillaceae Bacteria 1VNS7@1239,2EGZM@1,33ARR@2,3F83W@33958,4HSZW@91061 NA|NA|NA S Domain of unknown function (DUF4828) KIAJIJGH_00822 334390.LAF_1437 4.4e-103 380.6 Lactobacillaceae yvdD 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 Bacteria 1UKED@1239,3F5U4@33958,4HE2X@91061,COG1611@1,COG1611@2 NA|NA|NA S Belongs to the LOG family KIAJIJGH_00823 334390.LAF_1438 1.6e-160 572.0 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1UXY2@1239,3F4M2@33958,4HD1S@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily KIAJIJGH_00824 334390.LAF_1439 1.2e-163 582.4 Lactobacillaceae gshF 6.3.2.2 ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 M00118,M00582 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TPGX@1239,3F506@33958,4HAMJ@91061,COG2918@1,COG2918@2 NA|NA|NA H Belongs to the glutamate--cysteine ligase type 1 family KIAJIJGH_00826 334390.LAF_0614 4.6e-42 176.8 Lactobacillaceae rpsO GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02956 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VA5C@1239,3F7DV@33958,4HKE9@91061,COG0184@1,COG0184@2 NA|NA|NA J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome KIAJIJGH_00827 334390.LAF_0613 2.3e-35 154.5 Lactobacillaceae rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02968 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEGX@1239,3F7D8@33958,4HNJS@91061,COG0268@1,COG0268@2 NA|NA|NA J Binds directly to 16S ribosomal RNA KIAJIJGH_00828 334390.LAF_0611 7e-184 649.8 Lactobacillaceae holA 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TRM0@1239,3F3TP@33958,4HBB4@91061,COG1466@1,COG1466@2 NA|NA|NA L DNA polymerase III delta subunit KIAJIJGH_00829 334390.LAF_0610 0.0 1411.4 Lactobacillaceae comEC ko:K02238 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 1TS9U@1239,3F3VT@33958,4H9M4@91061,COG0658@1,COG0658@2,COG2333@1,COG2333@2 NA|NA|NA S Competence protein ComEC KIAJIJGH_00830 334390.LAF_0609 3.4e-88 330.9 Lactobacillaceae comEB 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 Bacteria 1V3PU@1239,3F6BF@33958,4HCDG@91061,COG2131@1,COG2131@2 NA|NA|NA F ComE operon protein 2 KIAJIJGH_00831 334390.LAF_0608 1.3e-90 339.3 Lactobacillaceae comEA ko:K02237 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 1VA3W@1239,3F7NP@33958,4HKJ1@91061,COG1555@1,COG1555@2 NA|NA|NA L Competence protein ComEA KIAJIJGH_00832 334390.LAF_0607 4.3e-197 693.7 Lactobacillaceae ylbL ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Bacteria 1TRUF@1239,3F4KY@33958,4HBAY@91061,COG3480@1,COG3480@2 NA|NA|NA T Belongs to the peptidase S16 family KIAJIJGH_00833 334390.LAF_0606 4.8e-88 330.5 Lactobacillaceae coaD GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0015939,GO:0015940,GO:0016043,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046390,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 iPC815.YPO0053,iSDY_1059.SDY_4064 Bacteria 1V3MR@1239,3F6YS@33958,4HH47@91061,COG0669@1,COG0669@2 NA|NA|NA H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate KIAJIJGH_00834 334390.LAF_0605 1.3e-99 369.0 Lactobacillaceae rsmD 2.1.1.171 ko:K08316 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 1V3JF@1239,3F505@33958,4HGXT@91061,COG0742@1,COG0742@2 NA|NA|NA L RNA methyltransferase, RsmD family KIAJIJGH_00835 334390.LAF_0604 1.4e-47 195.3 Bacteria ylbG Bacteria COG4471@1,COG4471@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2129) KIAJIJGH_00836 334390.LAF_0603 3.1e-215 754.2 Lactobacillaceae ftsW ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 2.A.103.1 Bacteria 1TPT7@1239,3F4IK@33958,4HAEV@91061,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family KIAJIJGH_00837 334390.LAF_0602 0.0 1211.8 Lactobacillaceae typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 ko:K06207 ko00000 Bacteria 1TQ5Y@1239,3F3UK@33958,4HAQ6@91061,COG1217@1,COG1217@2 NA|NA|NA T GTP-binding protein TypA KIAJIJGH_00838 334390.LAF_0601 2.8e-137 494.6 Lactobacillaceae suhB 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1TR4E@1239,3F5BB@33958,4HB92@91061,COG0483@1,COG0483@2 NA|NA|NA G Belongs to the inositol monophosphatase superfamily KIAJIJGH_00839 334390.LAF_0600 2.4e-49 201.1 Lactobacillaceae yktA ko:K16509 ko00000 Bacteria 1VEK8@1239,3F80A@33958,4HNKR@91061,COG4476@1,COG4476@2 NA|NA|NA S Belongs to the UPF0223 family KIAJIJGH_00840 334390.LAF_0599 7.5e-103 379.8 Lactobacillaceae def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.31,3.5.1.88 ko:K01450,ko:K01462 ko00270,ko00630,map00270,map00630 R00653 RC00165,RC00323 ko00000,ko00001,ko01000 Bacteria 1V70B@1239,3F3YH@33958,4HH0G@91061,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions KIAJIJGH_00841 334390.LAF_0598 1.5e-74 285.4 Lactobacillaceae Bacteria 1VQPI@1239,2C389@1,2ZQCN@2,3F79N@33958,4I0G9@91061 NA|NA|NA KIAJIJGH_00842 334390.LAF_0597 2.2e-31 141.0 Lactobacillaceae ykzG Bacteria 1VEI7@1239,3F807@33958,4HNSK@91061,COG5503@1,COG5503@2 NA|NA|NA S Belongs to the UPF0356 family KIAJIJGH_00843 334390.LAF_0596 2.4e-186 657.9 Lactobacillaceae ytlR 2.7.1.91 ko:K04718 ko00600,ko01100,ko04020,ko04071,ko04072,ko04370,ko04371,ko04666,ko05152,map00600,map01100,map04020,map04071,map04072,map04370,map04371,map04666,map05152 M00100 R01926,R02976 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQJH@1239,3FBKT@33958,4HJ8D@91061,COG1597@1,COG1597@2 NA|NA|NA I Diacylglycerol kinase catalytic KIAJIJGH_00844 334390.LAF_0595 4.2e-74 283.9 Lactobacillaceae spx4 1.20.4.1 ko:K00537,ko:K16509 ko00000,ko01000 Bacteria 1TTEA@1239,3F6ZW@33958,4I3R5@91061,COG1393@1,COG1393@2 NA|NA|NA P ArsC family KIAJIJGH_00845 334390.LAF_0594 2.1e-177 628.2 Lactobacillaceae prs 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2848 Bacteria 1TQ6Q@1239,3FCBW@33958,4HV42@91061,COG0462@1,COG0462@2 NA|NA|NA F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) KIAJIJGH_00846 334390.LAF_0593 0.0 1635.2 Lactobacillaceae recD 3.1.11.5 ko:K01144,ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPZH@1239,3F44X@33958,4HATQ@91061,COG0507@1,COG0507@2 NA|NA|NA L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity KIAJIJGH_00847 334390.LAF_0592 7.1e-124 449.9 Lactobacillaceae Bacteria 1VFGR@1239,3F4MD@33958,4IBSH@91061,COG0457@1,COG0457@2 NA|NA|NA S Repeat protein KIAJIJGH_00848 334390.LAF_0591 4.1e-121 440.7 Lactobacillaceae pgm6 5.4.2.11,5.4.2.12 ko:K01834,ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1V6ES@1239,3F3U3@33958,4HGZI@91061,COG0406@1,COG0406@2 NA|NA|NA G phosphoglycerate mutase KIAJIJGH_00849 334390.LAF_0590 4e-170 604.0 Lactobacillaceae ldh 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 Bacteria 1UXY2@1239,3F4M2@33958,4HD1S@91061,COG0039@1,COG0039@2 NA|NA|NA C Belongs to the LDH MDH superfamily KIAJIJGH_00850 334390.LAF_0589 1.5e-305 1054.7 Lactobacillaceae Bacteria 1TQ6G@1239,3F4DW@33958,4HC54@91061,COG1574@1,COG1574@2 NA|NA|NA S amidohydrolase KIAJIJGH_00851 334390.LAF_0588 1.3e-223 781.9 Lactobacillaceae mnmA GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 Bacteria 1TPIZ@1239,3F4N5@33958,4HBJ6@91061,COG0482@1,COG0482@2 NA|NA|NA J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 KIAJIJGH_00852 334390.LAF_0587 3.4e-58 230.7 Lactobacillaceae XK27_04120 Bacteria 1VDSF@1239,2DHWG@1,32U9W@2,3F7E3@33958,4HP9N@91061 NA|NA|NA S Putative amino acid metabolism KIAJIJGH_00853 334390.LAF_0586 4.6e-126 457.2 Lactobacillaceae mtnN 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 Bacteria 1U7WK@1239,3F4HE@33958,4HB8K@91061,COG0775@1,COG0775@2 NA|NA|NA E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively KIAJIJGH_00855 334390.LAF_0584 2.7e-97 361.3 Lactobacillaceae nudF 3.6.1.13 ko:K01515 ko00230,map00230 R01054 RC00002 ko00000,ko00001,ko01000 iHN637.CLJU_RS05505,iSB619.SA_RS07540,iYO844.BSU23610 Bacteria 1V6F5@1239,3F53J@33958,4HII9@91061,COG0494@1,COG0494@2 NA|NA|NA L ADP-ribose pyrophosphatase KIAJIJGH_00856 334390.LAF_0583 1.2e-32 145.2 Lactobacillaceae cspB ko:K03704 ko00000,ko03000 Bacteria 1W688@1239,3F81I@33958,4I1Y3@91061,COG1278@1,COG1278@2 NA|NA|NA K Cold shock protein KIAJIJGH_00857 334390.LAF_0582 0.0 1894.4 Lactobacillaceae ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_0027,iPC815.YPO0475 Bacteria 1TPS7@1239,3F3X4@33958,4HAWB@91061,COG0060@1,COG0060@2 NA|NA|NA J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) KIAJIJGH_00859 334390.LAF_0581 1.4e-111 409.1 Lactobacillaceae divIVA ko:K04074 ko00000,ko03036 Bacteria 1V27M@1239,3F4IN@33958,4HG80@91061,COG3599@1,COG3599@2 NA|NA|NA D DivIVA domain protein KIAJIJGH_00860 334390.LAF_0580 3.8e-145 520.8 Lactobacillaceae ylmH ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 Bacteria 1U5V2@1239,3F48W@33958,4HD3F@91061,COG2302@1,COG2302@2 NA|NA|NA S S4 domain protein KIAJIJGH_00861 334390.LAF_0579 6.8e-41 172.9 Lactobacillaceae yggT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02221 ko00000,ko02044 Bacteria 1VEKA@1239,3F843@33958,4HNJR@91061,COG0762@1,COG0762@2 NA|NA|NA S YGGT family KIAJIJGH_00862 334390.LAF_0578 2.5e-75 288.1 Lactobacillaceae sepF GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0044464,GO:0051301,GO:0071840,GO:0071944,GO:0090529 ko:K09772 ko00000,ko03036 Bacteria 1VER3@1239,3F7MQ@33958,4HKIC@91061,COG1799@1,COG1799@2 NA|NA|NA D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA KIAJIJGH_00863 334390.LAF_0577 9e-221 772.7 Lactobacillaceae ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Bacteria 1TP6W@1239,3F4V1@33958,4H9WZ@91061,COG0206@1,COG0206@2 NA|NA|NA D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity KIAJIJGH_00864 334390.LAF_0576 4.2e-224 783.9 Lactobacillaceae ftsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562 ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Bacteria 1TP1Z@1239,3F413@33958,4H9NF@91061,COG0849@1,COG0849@2 NA|NA|NA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring KIAJIJGH_00865 334390.LAF_0575 1.9e-150 538.5 Lactobacillaceae divIB ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Bacteria 1V6V5@1239,3F406@33958,4HDFD@91061,COG1589@1,COG1589@2 NA|NA|NA D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex KIAJIJGH_00866 334390.LAF_0574 2.3e-201 708.0 Lactobacillaceae murG GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227,6.3.2.8 ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 R03193,R05032,R05662 RC00005,RC00049,RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 GT28 iLJ478.TM0232,iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089 Bacteria 1TQFT@1239,3F4FW@33958,4HBAQ@91061,COG0707@1,COG0707@2 NA|NA|NA M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) KIAJIJGH_00867 334390.LAF_0573 2.8e-260 904.0 Lactobacillaceae murD 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1TQ3P@1239,3F49W@33958,4HA5P@91061,COG0771@1,COG0771@2 NA|NA|NA M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) KIAJIJGH_00868 334390.LAF_0572 9.1e-178 629.4 Lactobacillaceae mraY GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105 Bacteria 1TP8W@1239,3F3YP@33958,4H9TP@91061,COG0472@1,COG0472@2 NA|NA|NA M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan KIAJIJGH_00869 334390.LAF_0571 0.0 1234.6 Lactobacillaceae ftsI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 ko:K03587,ko:K08384,ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 iSSON_1240.SSON_0092 Bacteria 1TP93@1239,3F47N@33958,4H9VQ@91061,COG0768@1,COG0768@2 NA|NA|NA M Penicillin-binding Protein KIAJIJGH_00870 334390.LAF_0570 7e-09 67.0 Lactobacillaceae ftsL Bacteria 1VCE5@1239,3F6KG@33958,4HM4W@91061,COG4839@1,COG4839@2 NA|NA|NA D Cell division protein FtsL KIAJIJGH_00871 334390.LAF_0569 2.5e-172 611.3 Lactobacillaceae rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 ko00000,ko01000,ko03009 Bacteria 1TNZV@1239,3F3MF@33958,4H9U2@91061,COG0275@1,COG0275@2 NA|NA|NA J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA KIAJIJGH_00872 334390.LAF_0568 5.6e-79 300.1 Lactobacillaceae mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 ko:K03925 ko00000 Bacteria 1V3JD@1239,3F6K3@33958,4HH23@91061,COG2001@1,COG2001@2 NA|NA|NA K Belongs to the MraZ family KIAJIJGH_00873 334390.LAF_0567 5.8e-58 229.9 Lactobacillaceae Bacteria 1U6JI@1239,29PGG@1,30AEM@2,3F81C@33958,4IGC0@91061 NA|NA|NA KIAJIJGH_00874 1423814.HMPREF0549_0182 1.2e-07 61.2 Lactobacillaceae Bacteria 1U73D@1239,29PVH@1,30ATR@2,3F8XG@33958,4IGXZ@91061 NA|NA|NA S Protein of unknown function (DUF4044) KIAJIJGH_00875 334390.LAF_0566 0.0 1361.3 Lactobacillaceae ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 ko:K03466 ko00000,ko03036 3.A.12 Bacteria 1TPJR@1239,3F3JZ@33958,4H9WA@91061,COG1674@1,COG1674@2 NA|NA|NA D Belongs to the FtsK SpoIIIE SftA family KIAJIJGH_00876 334390.LAF_0565 6.7e-95 353.2 Lactobacillaceae trmL GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 ko:K03216 ko00000,ko01000,ko03016 Bacteria 1V3GW@1239,3F42Y@33958,4HFNY@91061,COG0219@1,COG0219@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily KIAJIJGH_00877 334390.LAF_0564 4.1e-161 573.9 Lactobacillaceae rrmA 2.1.1.187 ko:K00563,ko:K10947 R07233 RC00003 ko00000,ko01000,ko03000,ko03009 Bacteria 1V1WE@1239,3F4U3@33958,4HGQ9@91061,COG0500@1,COG2226@2 NA|NA|NA H Methyltransferase KIAJIJGH_00878 334390.LAF_0563 2.3e-195 688.0 Lactobacillaceae pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0017057,GO:0044424,GO:0044444,GO:0044464,GO:0052689 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ3J@1239,3F3RC@33958,4HBHB@91061,COG2706@1,COG2706@2 NA|NA|NA G Lactonase, 7-bladed beta-propeller KIAJIJGH_00879 334390.LAF_0562 8.2e-173 612.8 Lactobacillaceae rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 ko00000,ko01000,ko03009,ko03016 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 1TS1T@1239,3F4AU@33958,4HBRY@91061,COG0564@1,COG0564@2 NA|NA|NA G Responsible for synthesis of pseudouridine from uracil KIAJIJGH_00880 334390.LAF_0561 1e-153 549.3 Lactobacillaceae nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 R00104 RC00002,RC00078 ko00000,ko00001,ko01000 iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895 Bacteria 1TRB3@1239,3F45D@33958,4HB08@91061,COG0061@1,COG0061@2 NA|NA|NA F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP KIAJIJGH_00881 334390.LAF_0560 6e-123 446.8 Lactobacillaceae yjbM 2.7.6.5 ko:K07816 ko00230,map00230 R00429 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 1TQ2F@1239,3F452@33958,4HA3Q@91061,COG2357@1,COG2357@2 NA|NA|NA S RelA SpoT domain protein KIAJIJGH_00882 334390.LAF_0559 5.2e-113 413.7 Lactobacillaceae yjbH GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 Bacteria 1TQ8K@1239,3F6QR@33958,4HAI8@91061,COG2761@1,COG2761@2 NA|NA|NA Q Thioredoxin KIAJIJGH_00883 334390.LAF_0558 1.4e-203 715.3 Lactobacillaceae coiA 3.6.4.12 ko:K03657,ko:K06198 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TRGD@1239,3F4BZ@33958,4HFP5@91061,COG4469@1,COG4469@2 NA|NA|NA S Competence protein KIAJIJGH_00884 334390.LAF_0557 5.3e-114 417.2 Lactobacillaceae mecA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K16511 ko00000 Bacteria 1UZ7D@1239,3F5G4@33958,4HID6@91061,COG4862@1,COG4862@2 NA|NA|NA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis KIAJIJGH_00885 334390.LAF_0556 1.7e-69 268.5 Lactobacillaceae spxA 1.20.4.1 ko:K00537,ko:K16509 ko00000,ko01000 Bacteria 1V3QC@1239,3F6HJ@33958,4HH0I@91061,COG1393@1,COG1393@2 NA|NA|NA K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress KIAJIJGH_00886 1423814.HMPREF0549_0169 7.1e-17 94.0 Lactobacillaceae traP GO:0005575,GO:0016020 1.14.99.57,6.2.1.3 ko:K01897,ko:K21481 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 Bacteria 1V501@1239,3F3UU@33958,4HHA2@91061,COG2329@1,COG2329@2 NA|NA|NA S enzyme involved in biosynthesis of extracellular polysaccharides KIAJIJGH_00906 334390.LAF_1205 1.2e-73 282.3 Lactobacillaceae pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00608,ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15490 Bacteria 1TQ96@1239,3F4BQ@33958,4H9M6@91061,COG0540@1,COG0540@2 NA|NA|NA F Belongs to the ATCase OTCase family KIAJIJGH_00907 334390.LAF_1201 1.4e-167 595.5 Lactobacillaceae pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 ko:K00226,ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15540 Bacteria 1TPFV@1239,3F4PJ@33958,4HA5H@91061,COG0167@1,COG0167@2 NA|NA|NA F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily KIAJIJGH_00908 334390.LAF_1200 6.1e-148 530.0 Lactobacillaceae yitU 3.1.3.104 ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R07280 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TREF@1239,3F47B@33958,4H9Y9@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase KIAJIJGH_00909 334390.LAF_1228 3.3e-153 547.7 Lactobacillaceae pstC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02037 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TSPP@1239,3F3NI@33958,4HC9H@91061,COG0573@1,COG0573@2 NA|NA|NA P probably responsible for the translocation of the substrate across the membrane KIAJIJGH_00910 334390.LAF_1229 3.7e-134 484.2 Lactobacillaceae pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TQ5X@1239,3F4ER@33958,4HBEB@91061,COG0226@1,COG0226@2 NA|NA|NA P Phosphate KIAJIJGH_00911 334390.LAF_1230 9.5e-72 276.2 Lactobacillaceae Bacteria 1TPWS@1239,3F61A@33958,4H9KP@91061,COG0745@1,COG0745@2 NA|NA|NA K Transcriptional regulatory protein, C-terminal domain protein KIAJIJGH_00912 334390.LAF_1230 1.4e-41 175.3 Lactobacillaceae Bacteria 1TPWS@1239,3F61A@33958,4H9KP@91061,COG0745@1,COG0745@2 NA|NA|NA K Transcriptional regulatory protein, C-terminal domain protein KIAJIJGH_00913 334390.LAF_1231 4.5e-92 344.0 Lactobacillaceae Bacteria 1U7XR@1239,2AGCM@1,316IA@2,3FAAW@33958,4IHV5@91061 NA|NA|NA KIAJIJGH_00914 1138822.PL11_10705 3.6e-77 294.3 Lactobacillaceae ko:K07483,ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 2.A.7.21 Bacteria 1V6PN@1239,3F5S2@33958,4HK4K@91061,COG2963@1,COG2963@2 NA|NA|NA L Helix-turn-helix domain KIAJIJGH_00915 1138822.PL11_10700 3.9e-105 387.5 Lactobacillaceae ko:K07497 ko00000 Bacteria 1TQQY@1239,3F59Y@33958,4HBHG@91061,COG2801@1,COG2801@2 NA|NA|NA L PFAM Integrase catalytic region KIAJIJGH_00916 1138822.PL11_10700 4.1e-33 146.7 Lactobacillaceae ko:K07497 ko00000 Bacteria 1TQQY@1239,3F59Y@33958,4HBHG@91061,COG2801@1,COG2801@2 NA|NA|NA L PFAM Integrase catalytic region KIAJIJGH_00917 334390.LAF_0409 6.1e-105 386.7 Lactobacillaceae ahpC 1.11.1.15 ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Bacteria 1TQU7@1239,3F50G@33958,4HA2M@91061,COG0450@1,COG0450@2 NA|NA|NA O Peroxiredoxin KIAJIJGH_00918 334390.LAF_0410 0.0 1087.0 Lactobacillaceae trxB2 1.8.1.9 ko:K00384 ko00450,map00450 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 Bacteria 1TNZS@1239,3F5GD@33958,4HD19@91061,COG0492@1,COG0492@2,COG3634@1,COG3634@2 NA|NA|NA C Thioredoxin domain KIAJIJGH_00919 927691.AEMI01000013_gene737 2.1e-131 475.3 Bacilli czcD ko:K16264 ko00000,ko02000 2.A.4.1 Bacteria 1TR92@1239,4HBCQ@91061,COG1230@1,COG1230@2 NA|NA|NA P cation diffusion facilitator family transporter KIAJIJGH_00920 334390.LAF_1395 6.5e-162 576.6 Lactobacillaceae Bacteria 1TPUW@1239,3F5JP@33958,4HDIE@91061,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family KIAJIJGH_00921 334390.LAF_1396 1.2e-246 858.6 Lactobacillaceae yxbA 6.3.1.12 ko:K17810 ko00000,ko01000 Bacteria 1TQPN@1239,3F3S7@33958,4HAB0@91061,COG3919@1,COG3919@2 NA|NA|NA S ATP-grasp enzyme KIAJIJGH_00922 334390.LAF_1396 2.6e-42 177.9 Lactobacillaceae yxbA 6.3.1.12 ko:K17810 ko00000,ko01000 Bacteria 1TQPN@1239,3F3S7@33958,4HAB0@91061,COG3919@1,COG3919@2 NA|NA|NA S ATP-grasp enzyme KIAJIJGH_00923 575594.ACOH01000026_gene7 7.2e-15 87.8 Lactobacillaceae Bacteria 1U656@1239,2BVSH@1,30A3J@2,3F72Y@33958,4IFV0@91061 NA|NA|NA KIAJIJGH_00924 334390.LAF_1399 3.6e-157 560.8 Lactobacillaceae ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TS5Y@1239,3F4BF@33958,4HBUA@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter, ATP-binding protein KIAJIJGH_00925 334390.LAF_1400 7.8e-64 249.6 Lactobacillaceae gntR1 ko:K07979 ko00000,ko03000 Bacteria 1VAC6@1239,3F721@33958,4HKVW@91061,COG1725@1,COG1725@2 NA|NA|NA K Transcriptional regulator, GntR family KIAJIJGH_00926 334390.LAF_1401 1.3e-14 85.1 Lactobacillaceae rfbB 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPWM@1239,3F3R6@33958,4HA3Y@91061,COG1088@1,COG1088@2 NA|NA|NA M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily KIAJIJGH_00927 334390.LAF_1833 6.6e-113 413.3 Lactobacillaceae lepB 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1V7H9@1239,3F56W@33958,4HMGQ@91061,COG0681@1,COG0681@2 NA|NA|NA U Belongs to the peptidase S26 family KIAJIJGH_00928 334390.LAF_1834 6.9e-292 1009.2 Lactobacillaceae murE 6.3.2.13,6.3.2.7 ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 R02786,R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 Bacteria 1TPQE@1239,3F3UE@33958,4H9T1@91061,COG0769@1,COG0769@2 NA|NA|NA M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan KIAJIJGH_00929 334390.LAF_1835 3.6e-293 1013.4 Lactobacillaceae murE 6.3.2.13,6.3.2.7 ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 R02786,R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 Bacteria 1TPQE@1239,3F3UE@33958,4H9T1@91061,COG0769@1,COG0769@2 NA|NA|NA M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan KIAJIJGH_00930 334390.LAF_1836 1.6e-293 1014.6 Lactobacillaceae asnB 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 R00578 RC00010 ko00000,ko00001,ko01000,ko01002 Bacteria 1TRPB@1239,3F3NT@33958,4HAIP@91061,COG0367@1,COG0367@2 NA|NA|NA E Asparagine synthase KIAJIJGH_00931 1203076.CAKF01000016_gene1780 6.6e-220 770.0 Lactobacillaceae lysP ko:K03293,ko:K11733 ko00000,ko02000 2.A.3.1,2.A.3.1.2 Bacteria 1UHNR@1239,3F4BG@33958,4HUT7@91061,COG0833@1,COG0833@2 NA|NA|NA E amino acid KIAJIJGH_00932 334390.LAF_1837 7e-49 199.9 Lactobacillaceae mscL GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 ko:K03282 ko00000,ko02000 1.A.22.1 Bacteria 1VA14@1239,3F6YZ@33958,4HKIA@91061,COG1970@1,COG1970@2 NA|NA|NA M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell KIAJIJGH_00933 264199.stu1091 2e-41 176.4 Bacilli Bacteria 1UJ3N@1239,2CEUT@1,2Z86D@2,4IT0Z@91061 NA|NA|NA S Core-2/I-Branching enzyme KIAJIJGH_00939 1449342.JQMR01000001_gene1689 1.9e-100 373.2 Carnobacteriaceae ko:K06919 ko00000 Bacteria 1UYRX@1239,27I2C@186828,4HC06@91061,COG3378@1,COG3378@2 NA|NA|NA S D5 N terminal like KIAJIJGH_00940 334390.LAF_0228 6.3e-151 540.0 Lactobacillaceae Bacteria 1UI5Y@1239,3F7AA@33958,4ISES@91061,COG5519@1,COG5519@2 NA|NA|NA L DNA replication protein KIAJIJGH_00942 1423732.BALS01000085_gene2014 7.1e-251 872.8 Lactobacillaceae Bacteria 1TRUS@1239,3F5ZY@33958,4HCCQ@91061,COG3039@1,COG3039@2 NA|NA|NA L Transposase DDE domain KIAJIJGH_00943 1138822.PL11_10555 1.4e-13 81.3 Lactobacillaceae Bacteria 1V8AJ@1239,3F6YY@33958,4HPGU@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) domain KIAJIJGH_00944 1133569.AHYZ01000017_gene1019 2.4e-193 681.4 Lactobacillaceae Bacteria 1TQN4@1239,3F5I0@33958,4HKTX@91061,COG4227@1,COG4227@2 NA|NA|NA L Psort location Cytoplasmic, score KIAJIJGH_00945 1122149.BACN01000143_gene320 2.6e-32 144.1 Lactobacillaceae Bacteria 1U69B@1239,29P8A@1,30A6D@2,3F7CJ@33958,4IG0G@91061 NA|NA|NA KIAJIJGH_00946 1291743.LOSG293_220250 0.0 1348.2 Lactobacillaceae traI 5.99.1.2 ko:K03169 ko00000,ko01000,ko03032 Bacteria 1TPJD@1239,3F4W6@33958,4HAZV@91061,COG0550@1,COG0550@2 NA|NA|NA L This gene contains a nucleotide ambiguity which may be the result of a sequencing error KIAJIJGH_00947 220668.45723573 1.3e-64 252.3 Lactobacillaceae Bacteria 1U5SV@1239,29NXD@1,309VH@2,3F6FI@33958,4IFGT@91061 NA|NA|NA KIAJIJGH_00948 220668.45723574 4.5e-152 543.9 Lactobacillaceae Bacteria 1VPIB@1239,2EN0Y@1,33FP4@2,3F4ME@33958,4HRWI@91061 NA|NA|NA KIAJIJGH_00949 334390.LAF_0035 3.3e-280 970.3 Lactobacillaceae cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0032502,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 ko:K06131 ko00564,ko01100,map00564,map01100 R07390 RC00017 ko00000,ko00001,ko01000 Bacteria 1TPKY@1239,3F3SF@33958,4H9TI@91061,COG1502@1,COG1502@2 NA|NA|NA I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol KIAJIJGH_00950 334390.LAF_0036 0.0 2424.0 Lactobacillaceae rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.3,3.6.4.12 ko:K01153,ko:K16899 ko00000,ko01000,ko02048,ko03400 Bacteria 1TQJW@1239,3F3RS@33958,4HAY6@91061,COG3857@1,COG3857@2 NA|NA|NA L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity KIAJIJGH_00951 334390.LAF_0037 1.1e-46 192.6 Lactobacillaceae addA 3.6.4.12 ko:K16898 ko00000,ko01000,ko03400 Bacteria 1TQ35@1239,3F3Z0@33958,4HA64@91061,COG1074@1,COG1074@2 NA|NA|NA L ATP-dependent helicase nuclease subunit A KIAJIJGH_00952 334390.LAF_0037 0.0 1119.8 Lactobacillaceae addA 3.6.4.12 ko:K16898 ko00000,ko01000,ko03400 Bacteria 1TQ35@1239,3F3Z0@33958,4HA64@91061,COG1074@1,COG1074@2 NA|NA|NA L ATP-dependent helicase nuclease subunit A KIAJIJGH_00953 334390.LAF_0038 2.6e-163 581.3 Lactobacillaceae yvgN Bacteria 1TPM1@1239,3F3PW@33958,4HARE@91061,COG0656@1,COG0656@2 NA|NA|NA C Aldo keto reductase KIAJIJGH_00954 334390.LAF_0039 3.4e-294 1016.9 Lactobacillaceae glpQ 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1UG1C@1239,3F3SZ@33958,4HCPQ@91061,COG0584@1,COG0584@2 NA|NA|NA C phosphodiesterase KIAJIJGH_00955 334390.LAF_0040 1.7e-65 255.0 Lactobacillaceae arsC 1.20.4.1 ko:K00537,ko:K16509 ko00000,ko01000 Bacteria 1VA5Q@1239,3F72U@33958,4HKQQ@91061,COG1393@1,COG1393@2 NA|NA|NA P Belongs to the ArsC family KIAJIJGH_00956 1121024.AUCD01000067_gene690 9.2e-79 300.4 Carnobacteriaceae natA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TR06@1239,27FQB@186828,4H9RX@91061,COG4152@1,COG4152@2 NA|NA|NA S Domain of unknown function (DUF4162) KIAJIJGH_00957 334390.LAF_0027 9.3e-58 231.1 Bacteria ysdA ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria COG1668@1,COG1668@2 NA|NA|NA CP transmembrane transport KIAJIJGH_00958 334390.LAF_1575 1.1e-113 416.0 Lactobacillaceae Bacteria 1V1QC@1239,3F65F@33958,4HH7E@91061,COG2963@1,COG2963@2 NA|NA|NA L Helix-turn-helix domain KIAJIJGH_00959 334390.LAF_1411 1e-23 115.5 Lactobacillaceae ko:K07483 ko00000 Bacteria 1VCC9@1239,3F6ZZ@33958,4HS8E@91061,COG2963@1,COG2963@2 NA|NA|NA L Transposase KIAJIJGH_00960 334390.LAF_0778 2.4e-133 481.5 Lactobacillaceae Bacteria 1TQEG@1239,3F43M@33958,4HD6M@91061,COG2801@1,COG2801@2 NA|NA|NA L hmm pf00665 KIAJIJGH_00962 334390.LAF_0656 2e-88 332.0 Lactobacillaceae Bacteria 1W3AZ@1239,28UQM@1,2ZGUY@2,3F65Q@33958,4I0YM@91061 NA|NA|NA KIAJIJGH_00963 334390.LAF_0655 3.2e-77 294.3 Lactobacillaceae Bacteria 1U5KZ@1239,3F74G@33958,4IFBV@91061,COG3613@1,COG3613@2 NA|NA|NA F Nucleoside 2-deoxyribosyltransferase KIAJIJGH_00964 334390.LAF_0654 1.8e-181 641.7 Lactobacillaceae scrR3 ko:K02529,ko:K03484 ko00000,ko03000 Bacteria 1TQ7K@1239,3F4JE@33958,4H9V1@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator, LacI family KIAJIJGH_00965 1144319.PMI16_00349 2.3e-14 85.5 Proteobacteria Bacteria 1NN1P@1224,2EFW6@1,339NE@2 NA|NA|NA KIAJIJGH_00966 1071400.LBUCD034_0161 1.7e-17 95.1 Lactobacillaceae hbd2 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 Bacteria 1TPJS@1239,3F5ZF@33958,4HA59@91061,COG1250@1,COG1250@2 NA|NA|NA I 3-hydroxyacyl-CoA dehydrogenase KIAJIJGH_00967 334390.LAF_0646 0.0 1095.5 Lactobacillaceae asnB GO:0000166,GO:0003674,GO:0003824,GO:0004066,GO:0004071,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006541,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016054,GO:0016211,GO:0016597,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0017076,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0034641,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 R00578 RC00010 ko00000,ko00001,ko01000,ko01002 iB21_1397.B21_00622,iECBD_1354.ECBD_2988,iECB_1328.ECB_00631,iECD_1391.ECD_00631,iEcHS_1320.EcHS_A0717,iEcolC_1368.EcolC_2982,iSF_1195.SF0619 Bacteria 1TRPB@1239,3F5CH@33958,4HAIP@91061,COG0367@1,COG0367@2 NA|NA|NA E Aluminium induced protein KIAJIJGH_00969 334390.LAF_0642 9.9e-08 62.4 Lactobacillaceae Bacteria 1UXZQ@1239,3F6EF@33958,4IFG4@91061,COG0110@1,COG0110@2 NA|NA|NA S Bacterial transferase hexapeptide (six repeats) KIAJIJGH_00970 334390.LAF_0641 5e-119 434.1 Lactobacillaceae Bacteria 1TSJI@1239,3F5I6@33958,4HG70@91061,COG1028@1,COG1028@2 NA|NA|NA IQ Enoyl-(Acyl carrier protein) reductase KIAJIJGH_00971 334390.LAF_0639 6.3e-199 699.9 Lactobacillaceae gldA 1.1.1.6 ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 R01034,R10715,R10717 RC00029,RC00117,RC00670 ko00000,ko00001,ko01000 Bacteria 1TQFU@1239,3F4E4@33958,4HC8K@91061,COG0371@1,COG0371@2 NA|NA|NA C dehydrogenase KIAJIJGH_00972 324831.LGAS_0575 1.7e-16 92.0 Lactobacillaceae xre Bacteria 1VK84@1239,3F85V@33958,4HRBT@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix domain KIAJIJGH_00973 334390.LAF_0638 4.3e-50 203.8 Lactobacillaceae ko:K15383 ko00000,ko02000 9.A.58.2 Bacteria 1VBI9@1239,3F7IR@33958,4HMY5@91061,COG4095@1,COG4095@2 NA|NA|NA S Sugar efflux transporter for intercellular exchange KIAJIJGH_00974 334390.LAF_0637 1.5e-55 221.9 Lactobacillaceae 1.14.99.57 ko:K06996,ko:K21481 ko00000,ko01000 Bacteria 1VAH9@1239,3FBMM@33958,4IR6P@91061,COG1359@1,COG1359@2 NA|NA|NA S Antibiotic biosynthesis monooxygenase KIAJIJGH_00975 334390.LAF_0636 4.6e-45 186.8 Lactobacillaceae Bacteria 1U89D@1239,3FAQG@33958,4II7A@91061,COG2350@1,COG2350@2 NA|NA|NA S Protein conserved in bacteria KIAJIJGH_00976 334390.LAF_0635 6.2e-99 366.7 Lactobacillaceae ywrO ko:K11748 ko00000,ko02000 2.A.37.1.2 Bacteria 1V4UF@1239,3F6XY@33958,4HIR3@91061,COG2249@1,COG2249@2 NA|NA|NA S Flavodoxin-like fold KIAJIJGH_00977 1033837.WANG_1275 2.9e-43 181.4 Lactobacillaceae adhR Bacteria 1VAAP@1239,3F6JI@33958,4HKZ9@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance KIAJIJGH_00978 334390.LAF_1434 4.7e-25 120.2 Lactobacillaceae yfmL GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 1TQ9R@1239,3F4K8@33958,4HANR@91061,COG0513@1,COG0513@2 NA|NA|NA L DEAD DEAH box helicase KIAJIJGH_00981 334390.LAF_1433 3.9e-75 287.3 Lactobacillaceae gtcA GO:0000166,GO:0003674,GO:0003824,GO:0003870,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009987,GO:0016020,GO:0016410,GO:0016491,GO:0016620,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0016903,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 Bacteria 1VESW@1239,3F4GH@33958,4HNK7@91061,COG2246@1,COG2246@2 NA|NA|NA S Teichoic acid glycosylation protein KIAJIJGH_00982 334390.LAF_1432 1.2e-76 292.4 Lactobacillaceae fld ko:K03839 ko00000 Bacteria 1V7AG@1239,3F6HY@33958,4HMJF@91061,COG0716@1,COG0716@2 NA|NA|NA C Flavodoxin KIAJIJGH_00983 334390.LAF_1431 1.7e-167 595.1 Lactobacillaceae map GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605 3.4.11.18 ko:K01265 ko00000,ko01000,ko01002 Bacteria 1TQC1@1239,3F3MK@33958,4H9S9@91061,COG0024@1,COG0024@2 NA|NA|NA E Methionine Aminopeptidase KIAJIJGH_00984 334390.LAF_1430 0.0 1912.1 Lactobacillaceae XK27_08315 Bacteria 1TQYQ@1239,3F3NY@33958,4HBY6@91061,COG1368@1,COG1368@2 NA|NA|NA M Sulfatase KIAJIJGH_00985 334390.LAF_1429 2.7e-139 501.5 Lactobacillaceae yihY ko:K07058 ko00000 Bacteria 1U7HM@1239,3F4TC@33958,4H9MJ@91061,COG1295@1,COG1295@2 NA|NA|NA S Belongs to the UPF0761 family KIAJIJGH_00986 334390.LAF_1428 3.8e-31 140.2 Firmicutes Bacteria 1VKCM@1239,2DR42@1,33A2M@2 NA|NA|NA S Protein of unknown function (DUF2922) KIAJIJGH_00987 575594.ACOH01000006_gene332 1.3e-07 62.0 Lactobacillaceae Bacteria 1U8EX@1239,29QPR@1,30BPF@2,3FAWR@33958,4IICT@91061 NA|NA|NA KIAJIJGH_00988 334390.LAF_1426 5.5e-147 526.9 Lactobacillaceae recX GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019899,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496 2.4.1.337 ko:K03565,ko:K19002 ko00561,ko01100,map00561,map01100 R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003,ko03400 GT4 Bacteria 1V72V@1239,3F4BY@33958,4HJ7R@91061,COG2137@1,COG2137@2 NA|NA|NA S Regulatory protein RecX KIAJIJGH_00989 334390.LAF_1425 1.1e-118 432.6 Lactobacillaceae rfbP ko:K13012 ko00000,ko01005 Bacteria 1TP7M@1239,3F51J@33958,4HCBG@91061,COG2148@1,COG2148@2 NA|NA|NA M Bacterial sugar transferase KIAJIJGH_00990 334390.LAF_1424 1.1e-146 525.8 Lactobacillaceae cps1D Bacteria 1U6EG@1239,3F539@33958,4HG4F@91061,COG1442@1,COG1442@2 NA|NA|NA M Domain of unknown function (DUF4422) KIAJIJGH_00991 349123.Lreu23DRAFT_4284 2.8e-94 352.4 Lactobacillaceae cps3F Bacteria 1VDRM@1239,2DN9M@1,32W9S@2,3F6CA@33958,4HRQ0@91061 NA|NA|NA KIAJIJGH_00992 349123.Lreu23DRAFT_4283 5.9e-45 187.6 Lactobacillaceae ko:K16692 ko00000,ko01000,ko01001 Bacteria 1W5Q7@1239,3F84M@33958,4HZIW@91061,COG3944@1,COG3944@2 NA|NA|NA M biosynthesis protein KIAJIJGH_00993 334390.LAF_1413 1.5e-49 203.8 Lactobacillaceae cps3I Bacteria 1V858@1239,3F6SS@33958,4HJH5@91061,COG3594@1,COG3594@2 NA|NA|NA G Acyltransferase family KIAJIJGH_00994 334390.LAF_1416 5.7e-09 65.9 Lactobacillaceae glf GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071840,GO:0071944 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 iNJ661.Rv3809c Bacteria 1TQB9@1239,3F52G@33958,4HB5F@91061,COG0562@1,COG0562@2 NA|NA|NA M UDP-galactopyranose mutase KIAJIJGH_00995 203120.LEUM_1399 3e-63 250.0 Leuconostocaceae Bacteria 1V4M1@1239,2DGTK@1,2ZX8T@2,4AY6N@81850,4ISSZ@91061 NA|NA|NA KIAJIJGH_00996 944562.HMPREF9102_0232 8.8e-133 479.9 Lactobacillaceae rfbJ Bacteria 1UI8D@1239,3F49C@33958,4IST0@91061,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase family 2 KIAJIJGH_00997 334390.LAF_1416 5.1e-220 770.0 Lactobacillaceae glf GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071840,GO:0071944 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 iNJ661.Rv3809c Bacteria 1TQB9@1239,3F52G@33958,4HB5F@91061,COG0562@1,COG0562@2 NA|NA|NA M UDP-galactopyranose mutase KIAJIJGH_00998 334390.LAF_1415 2.5e-203 714.9 Lactobacillaceae rfbX Bacteria 1TP7R@1239,3F48Q@33958,4HC84@91061,COG2244@1,COG2244@2 NA|NA|NA S Membrane protein involved in the export of O-antigen and teichoic acid KIAJIJGH_01000 575594.ACOH01000007_gene343 7.5e-57 228.0 Lactobacillaceae acmD 3.2.1.17 ko:K01185,ko:K02395 ko00000,ko01000,ko02035 Bacteria 1UYRM@1239,3F4XJ@33958,4HAU6@91061,COG1705@1,COG1705@2 NA|NA|NA NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase KIAJIJGH_01001 334390.LAF_1410 3.2e-09 68.9 Lactobacillaceae ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1UJIC@1239,3F6PF@33958,4ITA9@91061,COG0791@1,COG0791@2,COG5263@1,COG5263@2 NA|NA|NA M repeat protein KIAJIJGH_01002 334390.LAF_1410 1.6e-59 236.9 Lactobacillaceae ko:K21471 ko00000,ko01000,ko01002,ko01011 Bacteria 1UJIC@1239,3F6PF@33958,4ITA9@91061,COG0791@1,COG0791@2,COG5263@1,COG5263@2 NA|NA|NA M repeat protein KIAJIJGH_01003 575594.ACOH01000008_gene347 2.1e-09 69.3 Lactobacillaceae Bacteria 1U6WM@1239,29PQC@1,30ANH@2,3F8MS@33958,4IGQU@91061 NA|NA|NA KIAJIJGH_01004 334390.LAF_1409 2.9e-160 571.2 Lactobacillaceae yfdH 2.4.2.53 ko:K10012,ko:K12999,ko:K13670 ko00520,ko01503,map00520,map01503 M00721,M00761 R07661 RC00005,RC02954 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko02000 4.D.2.1.8 GT2 Bacteria 1UHWE@1239,3F3JX@33958,4ISA4@91061,COG1216@1,COG1216@2 NA|NA|NA M Glycosyltransferase, group 2 family protein KIAJIJGH_01005 334390.LAF_1408 4.6e-68 264.2 Lactobacillaceae yueF GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 Bacteria 1TQ84@1239,3F418@33958,4H9SR@91061,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter KIAJIJGH_01006 334390.LAF_1408 1.5e-94 352.8 Lactobacillaceae yueF GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 Bacteria 1TQ84@1239,3F418@33958,4H9SR@91061,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter KIAJIJGH_01007 334390.LAF_1407 2.6e-164 584.7 Lactobacillaceae ykoT ko:K20534 ko00000,ko01000,ko01005,ko02000 4.D.2.1.9 GT2 Bacteria 1TPR3@1239,3F3X7@33958,4HC2Z@91061,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase family 2 KIAJIJGH_01008 334390.LAF_1404 7.7e-307 1058.9 Lactobacillaceae prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02837,ko:K07133 ko00000,ko03012 Bacteria 1TPYT@1239,3F489@33958,4HADS@91061,COG4108@1,COG4108@2 NA|NA|NA J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP KIAJIJGH_01009 1069534.LRC_01160 1.3e-95 356.7 Lactobacillaceae Bacteria 1V8J0@1239,3FBD0@33958,4HVPH@91061,COG0438@1,COG0438@2 NA|NA|NA M transferase activity, transferring glycosyl groups KIAJIJGH_01010 353496.LBU_1592 7e-103 380.6 Lactobacillaceae glfT1 1.1.1.133 ko:K00067,ko:K07011 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 Bacteria 1V4NS@1239,3F6P7@33958,4HHDW@91061,COG1216@1,COG1216@2 NA|NA|NA S Glycosyltransferase like family 2 KIAJIJGH_01011 1221537.B807_199 1.1e-88 334.3 Lactobacillaceae Bacteria 1V83S@1239,3F5ER@33958,4HY51@91061,COG4485@1,COG4485@2 NA|NA|NA S Bacterial membrane protein, YfhO KIAJIJGH_01012 543734.LCABL_13600 1.1e-78 299.3 Lactobacillaceae tspO ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 9.A.24 Bacteria 1V896@1239,3F6ED@33958,4HK1B@91061,COG3476@1,COG3476@2 NA|NA|NA T TspO/MBR family KIAJIJGH_01013 1423732.BALS01000006_gene697 3.2e-13 80.1 Lactobacillaceae Bacteria 1U77Q@1239,29PYH@1,30AWY@2,3F930@33958,4IH2I@91061 NA|NA|NA KIAJIJGH_01014 641146.HMPREF9020_01154 1.4e-234 818.5 Bifidobacteriales Bacteria 2GJK7@201174,4D1TR@85004,COG3464@1,COG3464@2 NA|NA|NA L Transposase KIAJIJGH_01015 1423807.BACO01000021_gene690 7.7e-13 80.9 Lactobacillaceae Bacteria 1VZSI@1239,29W71@1,30HS8@2,3F4M9@33958,4IEVP@91061 NA|NA|NA S Domain of unknown function (DUF4767) KIAJIJGH_01016 1138822.PL11_10605 5e-287 993.0 Lactobacillaceae Bacteria 1TQST@1239,3F47D@33958,4HPQC@91061,COG4974@1,COG4974@2 NA|NA|NA L Transposase IS66 family KIAJIJGH_01017 1203076.CAKF01000021_gene1477 6.3e-124 450.3 Lactobacillaceae Bacteria 1TRQC@1239,3F4FH@33958,4HD7P@91061,COG1028@1,COG1028@2 NA|NA|NA IQ reductase KIAJIJGH_01018 334390.LAF_1174 2.7e-51 207.6 Lactobacillaceae Bacteria 1TQEG@1239,3F43M@33958,4HD6M@91061,COG2801@1,COG2801@2 NA|NA|NA L hmm pf00665 KIAJIJGH_01019 546275.FUSPEROL_01937 9.5e-40 169.9 Bacteria bcgIA 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria COG0286@1,COG0286@2 NA|NA|NA V site-specific DNA-methyltransferase (adenine-specific) activity KIAJIJGH_01020 334390.LAF_1159 1.2e-78 299.3 Lactobacillaceae Bacteria 1TQWY@1239,3F75S@33958,4HW0R@91061,COG0583@1,COG0583@2 NA|NA|NA K Bacterial regulatory helix-turn-helix protein, lysR family KIAJIJGH_01021 334390.LAF_1160 7.7e-117 426.4 Lactobacillaceae cah 4.2.1.1 ko:K01674 ko00910,map00910 R00132,R10092 RC02807 ko00000,ko00001,ko01000 Bacteria 1V16J@1239,3F60I@33958,4HA62@91061,COG3338@1,COG3338@2 NA|NA|NA P Eukaryotic-type carbonic anhydrase KIAJIJGH_01022 334390.LAF_1161 0.0 1604.3 Lactobacillaceae carB 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 Bacteria 1VRNP@1239,3FC3W@33958,4HTJU@91061,COG0458@1,COG0458@2 NA|NA|NA F Carbamoyl-phosphate synthase KIAJIJGH_01023 334390.LAF_1162 3.4e-205 720.7 Lactobacillaceae carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955,ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1383,iYO844.BSU15510 Bacteria 1VTN5@1239,3FC4C@33958,4HT8S@91061,COG0505@1,COG0505@2 NA|NA|NA F Belongs to the CarA family KIAJIJGH_01024 334390.LAF_1163 1.7e-173 615.1 Lactobacillaceae rluD GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 ko00000,ko01000,ko03009 iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432 Bacteria 1TPCM@1239,3F3P6@33958,4HBG2@91061,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil KIAJIJGH_01025 334390.LAF_1164 3.9e-75 287.3 Lactobacillaceae lspA 3.4.23.36 ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Bacteria 1VA9R@1239,3F66R@33958,4HIR4@91061,COG0597@1,COG0597@2 NA|NA|NA MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins KIAJIJGH_01026 334390.LAF_1165 1.7e-70 271.9 Lactobacillaceae esbA Bacteria 1W31C@1239,2BZWG@1,2ZPAS@2,3F6SQ@33958,4I09H@91061 NA|NA|NA S Family of unknown function (DUF5322) KIAJIJGH_01027 334390.LAF_1166 3.1e-71 274.2 Lactobacillaceae rnhA 3.1.26.4 ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1VH2B@1239,3F7JC@33958,4HIY9@91061,COG0328@1,COG0328@2 NA|NA|NA L Ribonuclease HI KIAJIJGH_01028 334390.LAF_1167 9.7e-109 399.4 Lactobacillaceae XK27_02070 ko:K07078 ko00000 Bacteria 1V1CR@1239,3F576@33958,4HD6W@91061,COG3560@1,COG3560@2 NA|NA|NA S Nitroreductase family KIAJIJGH_01029 334390.LAF_1168 1e-156 559.3 Lactobacillaceae yckB ko:K02030,ko:K02424,ko:K16957 ko02010,map02010 M00234,M00236,M00585 ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3,3.A.1.3.10,3.A.1.3.13,3.A.1.3.14 Bacteria 1UHHG@1239,3FC57@33958,4H9NX@91061,COG0834@1,COG0834@2 NA|NA|NA ET Belongs to the bacterial solute-binding protein 3 family KIAJIJGH_01030 334390.LAF_1169 1e-117 429.5 Lactobacillaceae yecS GO:0000099,GO:0000101,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006791,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015184,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015811,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:0098656,GO:1901682,GO:1902475,GO:1903825,GO:1905039 ko:K10009 ko02010,map02010 M00234 ko00000,ko00001,ko00002,ko02000 3.A.1.3.10,3.A.1.3.14 iJN746.PP_0226 Bacteria 1TQ43@1239,3FC58@33958,4HCZV@91061,COG0765@1,COG0765@2 NA|NA|NA E ABC transporter permease KIAJIJGH_01031 334390.LAF_0921 5.4e-262 909.8 Lactobacillaceae arcD ko:K03758 ko00000,ko02000 2.A.3.2 Bacteria 1TSSB@1239,3F5SN@33958,4HA92@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino acid permease KIAJIJGH_01032 334390.LAF_0922 4.5e-199 700.3 Lactobacillaceae ilvE 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TQQI@1239,3F4BD@33958,4HASX@91061,COG0115@1,COG0115@2 NA|NA|NA E Branched-chain amino acid aminotransferase KIAJIJGH_01033 334390.LAF_0923 1.6e-106 392.1 Lactobacillaceae lacA 2.3.1.18,2.3.1.79 ko:K00633,ko:K00661 ko00000,ko01000 Bacteria 1TQQB@1239,3FC9A@33958,4HG1G@91061,COG0110@1,COG0110@2 NA|NA|NA S Maltose acetyltransferase KIAJIJGH_01034 1158610.UC3_01477 1.2e-50 206.1 Enterococcaceae yncA 2.3.1.79 ko:K00661 ko00000,ko01000 Bacteria 1U99W@1239,4B69N@81852,4HFQZ@91061,COG0110@1,COG0110@2 NA|NA|NA S Maltose acetyltransferase KIAJIJGH_01035 334390.LAF_0925 2.2e-93 348.2 Lactobacillaceae Bacteria 1VZV8@1239,3F66E@33958,4HYXN@91061,COG3177@1,COG3177@2 NA|NA|NA S Fic/DOC family KIAJIJGH_01036 334390.LAF_0926 4.6e-97 360.5 Lactobacillaceae apt 2.4.2.22,2.4.2.7 ko:K00759,ko:K03816,ko:K09685 ko00230,ko01100,ko01110,map00230,map01100,map01110 R00190,R01229,R02142,R04378 RC00063,RC00122 ko00000,ko00001,ko01000,ko03000,ko04147 Bacteria 1V1XS@1239,3F6EK@33958,4HG1T@91061,COG0503@1,COG0503@2 NA|NA|NA F Phosphoribosyl transferase domain KIAJIJGH_01037 334390.LAF_0927 1.4e-39 168.7 Lactobacillaceae ko:K08368 ko00000,ko02000 2.A.1 Bacteria 1UHPS@1239,3FBSX@33958,4HD28@91061,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter KIAJIJGH_01038 334390.LAF_0927 4.1e-113 414.1 Lactobacillaceae ko:K08368 ko00000,ko02000 2.A.1 Bacteria 1UHPS@1239,3FBSX@33958,4HD28@91061,COG0477@1,COG0477@2 NA|NA|NA EGP Sugar (and other) transporter KIAJIJGH_01039 334390.LAF_0928 6.2e-70 270.0 Lactobacillaceae 1.4.1.1,4.3.1.12 ko:K01750,ko:K19244 ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230 R00396,R00671 RC00008,RC00354 ko00000,ko00001,ko01000 Bacteria 1TPHM@1239,3F5HH@33958,4HBWI@91061,COG2423@1,COG2423@2 NA|NA|NA E Ornithine cyclodeaminase/mu-crystallin family KIAJIJGH_01040 334390.LAF_0928 1.8e-105 388.7 Lactobacillaceae 1.4.1.1,4.3.1.12 ko:K01750,ko:K19244 ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230 R00396,R00671 RC00008,RC00354 ko00000,ko00001,ko01000 Bacteria 1TPHM@1239,3F5HH@33958,4HBWI@91061,COG2423@1,COG2423@2 NA|NA|NA E Ornithine cyclodeaminase/mu-crystallin family KIAJIJGH_01041 334390.LAF_0929 1.1e-186 659.1 Lactobacillaceae 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 Bacteria 1TQPD@1239,3F3PZ@33958,4HE7P@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase KIAJIJGH_01042 334390.LAF_0929 6.3e-26 122.9 Lactobacillaceae 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 Bacteria 1TQPD@1239,3F3PZ@33958,4HE7P@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase KIAJIJGH_01045 334390.LAF_0931 1e-125 456.1 Lactobacillaceae Bacteria 1UZ30@1239,3FBV4@33958,4HBNN@91061,COG2369@1,COG2369@2 NA|NA|NA S Phage minor capsid protein 2 KIAJIJGH_01047 334390.LAF_0932 7.4e-163 579.7 Bacilli Bacteria 1V83G@1239,4HMC4@91061,COG0657@1,COG0657@2 NA|NA|NA I alpha/beta hydrolase fold KIAJIJGH_01048 334390.LAF_0452 1.4e-150 538.9 Lactobacillaceae 2.3.1.19 ko:K00634,ko:K07729 ko00650,ko01100,map00650,map01100 R01174 RC00004,RC02816 ko00000,ko00001,ko01000,ko03000 Bacteria 1VMYH@1239,3F5QH@33958,4ISF0@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins KIAJIJGH_01049 334390.LAF_0453 2.3e-81 308.1 Lactobacillaceae usp6 ko:K03499,ko:K06149 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1V3NY@1239,3F68T@33958,4HIP3@91061,COG0589@1,COG0589@2 NA|NA|NA T universal stress protein KIAJIJGH_01051 334390.LAF_0455 8.4e-235 819.3 Lactobacillaceae rarA ko:K07478 ko00000 Bacteria 1TPVV@1239,3F3WF@33958,4HAIS@91061,COG2256@1,COG2256@2 NA|NA|NA L recombination factor protein RarA KIAJIJGH_01052 334390.LAF_0456 4.5e-85 320.5 Lactobacillaceae yueI Bacteria 1VFCV@1239,3F64D@33958,4HNNE@91061,COG5506@1,COG5506@2 NA|NA|NA S Protein of unknown function (DUF1694) KIAJIJGH_01053 334390.LAF_0457 1.3e-75 288.9 Lactobacillaceae 4.4.1.5 ko:K01759 ko00620,map00620 R02530 RC00004,RC00740 ko00000,ko00001,ko01000 Bacteria 1V7XP@1239,3F679@33958,4HXCD@91061,COG0346@1,COG0346@2 NA|NA|NA E Glyoxalase KIAJIJGH_01054 334390.LAF_0458 5.3e-133 480.3 Lactobacillaceae Bacteria 1VSZX@1239,3F4ZU@33958,4HTJ1@91061,COG2364@1,COG2364@2 NA|NA|NA S Membrane KIAJIJGH_01055 334390.LAF_0459 2.3e-148 531.6 Lactobacillaceae Bacteria 1TRBT@1239,3F3PH@33958,4HBPR@91061,COG1284@1,COG1284@2 NA|NA|NA S Uncharacterised 5xTM membrane BCR, YitT family COG1284 KIAJIJGH_01056 257314.LJ_1435 2.1e-25 121.7 Lactobacillaceae Bacteria 1UPYE@1239,2ETGE@1,33M09@2,3F8I9@33958,4HS27@91061 NA|NA|NA S YjcQ protein KIAJIJGH_01058 334390.LAF_0487 1.7e-108 398.7 Lactobacillaceae rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 ko:K02986 ko03010,map03010 M00178,M00179 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TR0J@1239,3F3P0@33958,4HAC9@91061,COG0522@1,COG0522@2 NA|NA|NA J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit KIAJIJGH_01059 334390.LAF_0488 2.4e-306 1057.4 Lactobacillaceae ezrA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 ko:K06286,ko:K07158 ko00000,ko03036 Bacteria 1TQR7@1239,3F47K@33958,4HA15@91061,COG4477@1,COG4477@2 NA|NA|NA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization KIAJIJGH_01060 334390.LAF_0489 2.9e-215 754.2 Lactobacillaceae iscS2 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1TP21@1239,3F4CD@33958,4HAEE@91061,COG1104@1,COG1104@2 NA|NA|NA E Aminotransferase class V KIAJIJGH_01061 334390.LAF_0490 9.4e-228 795.8 Lactobacillaceae thiI GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07461 ko00000,ko00001,ko01000,ko03016 iECNA114_1301.ECNA114_0400,iECO26_1355.ECO26_0455,iECSF_1327.ECSF_0383,iSDY_1059.SDY_0307 Bacteria 1TPNW@1239,3F3N0@33958,4HAV9@91061,COG0301@1,COG0301@2 NA|NA|NA H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS KIAJIJGH_01062 334390.LAF_0491 2.9e-211 741.1 Lactobacillaceae ko:K03299 ko00000,ko02000 2.A.8 Bacteria 1TQ14@1239,3F57Q@33958,4HBI6@91061,COG2610@1,COG2610@2 NA|NA|NA EG GntP family permease KIAJIJGH_01063 334390.LAF_0492 6.1e-205 719.9 Lactobacillaceae glxK 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 R08572 RC00002,RC00428 ko00000,ko00001,ko01000 Bacteria 1TPSI@1239,3F3V2@33958,4HA91@91061,COG1929@1,COG1929@2 NA|NA|NA G Belongs to the glycerate kinase type-1 family KIAJIJGH_01064 1203076.CAKF01000006_gene363 1.2e-35 157.5 Lactobacillaceae Bacteria 1VQJH@1239,3F4H3@33958,4HSU2@91061,COG1388@1,COG1388@2 NA|NA|NA M LysM domain KIAJIJGH_01065 1203076.CAKF01000006_gene364 2e-39 168.7 Lactobacillaceae Bacteria 1VVCA@1239,2BXK6@1,33WGZ@2,3F6P3@33958,4HWEI@91061 NA|NA|NA KIAJIJGH_01066 862514.HMPREF0623_0917 8.4e-24 117.1 Lactobacillaceae Bacteria 1VGHA@1239,2E5BJ@1,3303M@2,3F9X1@33958,4HQ41@91061 NA|NA|NA S zinc-ribbon domain KIAJIJGH_01069 334390.LAF_0496 1.6e-88 332.0 Lactobacillaceae tpx 1.11.1.15 ko:K11065 ko00000,ko01000 Bacteria 1V474@1239,3F5VY@33958,4HFMW@91061,COG2077@1,COG2077@2 NA|NA|NA O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides KIAJIJGH_01070 334390.LAF_0497 0.0 1786.5 Lactobacillaceae valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iLJ478.TM1817 Bacteria 1TPN4@1239,3F3RB@33958,4HB85@91061,COG0525@1,COG0525@2 NA|NA|NA J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner KIAJIJGH_01071 334390.LAF_0498 4.7e-249 866.7 Lactobacillaceae folC 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0166 Bacteria 1TPX5@1239,3F498@33958,4HBJM@91061,COG0285@1,COG0285@2 NA|NA|NA H Belongs to the folylpolyglutamate synthase family KIAJIJGH_01072 334390.LAF_0499 2.5e-115 421.4 Lactobacillaceae radC ko:K03630 ko00000 Bacteria 1TQ3K@1239,3F5IM@33958,4HB1W@91061,COG2003@1,COG2003@2 NA|NA|NA L DNA repair protein KIAJIJGH_01073 334390.LAF_0500 1.9e-181 641.7 Lactobacillaceae mreB ko:K03569 ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 Bacteria 1TP51@1239,3F3ZV@33958,4HA4S@91061,COG1077@1,COG1077@2 NA|NA|NA D cell shape determining protein MreB KIAJIJGH_01074 334390.LAF_0501 3.7e-146 524.2 Lactobacillaceae mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963 ko:K03570 ko00000,ko03036 9.B.157.1 Bacteria 1TR1V@1239,3F3MC@33958,4HB0K@91061,COG1792@1,COG1792@2 NA|NA|NA M Involved in formation and maintenance of cell shape KIAJIJGH_01075 334390.LAF_0502 4.3e-92 344.0 Lactobacillaceae mreD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 ko:K03571 ko00000,ko03036 9.B.157.1 Bacteria 1VEV7@1239,3F6PG@33958,4HPAC@91061,COG2891@1,COG2891@2 NA|NA|NA M rod shape-determining protein MreD KIAJIJGH_01076 334390.LAF_0503 1.4e-108 399.1 Lactobacillaceae glnP ko:K02029,ko:K02030,ko:K17073,ko:K17074 ko02010,map02010 M00236,M00589 ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.20 Bacteria 1V280@1239,3F3VF@33958,4HGMH@91061,COG0765@1,COG0765@2 NA|NA|NA P ABC transporter permease KIAJIJGH_01077 334390.LAF_0504 2.2e-114 418.3 Lactobacillaceae glnQ 3.6.3.21 ko:K02028 M00236 ko00000,ko00002,ko01000,ko02000 3.A.1.3 Bacteria 1UYAZ@1239,3FC39@33958,4HFTM@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein KIAJIJGH_01078 334390.LAF_0505 2.4e-161 574.7 Lactobacillaceae aatB ko:K02029,ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TQNR@1239,3F3WC@33958,4HF14@91061,COG0834@1,COG0834@2 NA|NA|NA ET ABC transporter substrate-binding protein KIAJIJGH_01079 334390.LAF_0506 4.3e-231 807.0 Lactobacillaceae ymfF Bacteria 1TPN6@1239,3F3SA@33958,4H9P5@91061,COG0612@1,COG0612@2 NA|NA|NA S Peptidase M16 inactive domain protein KIAJIJGH_01080 334390.LAF_0507 1.7e-251 874.8 Lactobacillaceae ymfH ko:K07263 ko00000,ko01000,ko01002 Bacteria 1TP5I@1239,3F4MU@33958,4H9YG@91061,COG0612@1,COG0612@2 NA|NA|NA S Peptidase M16 KIAJIJGH_01081 334390.LAF_0508 1.8e-96 359.4 Lactobacillaceae ymfM ko:K15539 ko00000 Bacteria 1V9EA@1239,3FC82@33958,4HPRN@91061,COG1426@1,COG1426@2 NA|NA|NA S Helix-turn-helix domain KIAJIJGH_01082 334390.LAF_0509 1.1e-101 375.9 Lactobacillaceae pgsA GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 iSB619.SA_RS06365 Bacteria 1V6PJ@1239,3F4BI@33958,4HCEX@91061,COG0558@1,COG0558@2 NA|NA|NA I Belongs to the CDP-alcohol phosphatidyltransferase class-I family KIAJIJGH_01083 334390.LAF_0510 6e-230 803.1 Lactobacillaceae cinA GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 R02322 RC00100 ko00000,ko00001,ko01000 Bacteria 1TQ1N@1239,3F4I4@33958,4HATN@91061,COG1058@1,COG1058@2,COG1546@1,COG1546@2 NA|NA|NA S Belongs to the CinA family KIAJIJGH_01084 334390.LAF_0511 2.2e-193 681.4 Lactobacillaceae recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 ko:K03553 ko03440,map03440 M00729 ko00000,ko00001,ko00002,ko03400 Bacteria 1TPD5@1239,3F3KU@33958,4HAG5@91061,COG0468@1,COG0468@2 NA|NA|NA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage KIAJIJGH_01085 334390.LAF_0512 1e-202 713.0 Lactobacillaceae rny GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Bacteria 1TP48@1239,3F3WX@33958,4HC9J@91061,COG1418@1,COG1418@2 NA|NA|NA S Endoribonuclease that initiates mRNA decay KIAJIJGH_01086 334390.LAF_0513 0.0 1653.6 Lactobacillaceae mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1TPRJ@1239,3F4A5@33958,4HA63@91061,COG0249@1,COG0249@2 NA|NA|NA L that it carries out the mismatch recognition step. This protein has a weak ATPase activity KIAJIJGH_01087 334390.LAF_0514 0.0 1258.4 Lactobacillaceae mutL GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1TPGK@1239,3F3PK@33958,4HB34@91061,COG0323@1,COG0323@2 NA|NA|NA L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex KIAJIJGH_01088 334390.LAF_0515 1.1e-104 386.0 Lactobacillaceae ruvA GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1V3KF@1239,3F42W@33958,4HHI5@91061,COG0632@1,COG0632@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB KIAJIJGH_01089 334390.LAF_0516 1.1e-189 669.1 Lactobacillaceae ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TR47@1239,3F47S@33958,4HBMW@91061,COG2255@1,COG2255@2 NA|NA|NA L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing KIAJIJGH_01090 334390.LAF_0517 2.2e-176 624.8 Bacteria 2.4.2.29 ko:K00773 R03789,R10209 RC00063 ko00000,ko01000,ko03016 Bacteria COG0343@1,COG0343@2 NA|NA|NA F queuine tRNA-ribosyltransferase activity KIAJIJGH_01091 334390.LAF_0518 5.5e-42 177.2 Lactobacillaceae yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 Bacteria 1VEMC@1239,3F7EY@33958,4HNK0@91061,COG1862@1,COG1862@2 NA|NA|NA U Preprotein translocase KIAJIJGH_01092 334390.LAF_0519 6.8e-181 639.8 Lactobacillaceae nrnA GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPXX@1239,3F4FC@33958,4H9ZW@91061,COG0618@1,COG0618@2 NA|NA|NA S DHHA1 domain protein KIAJIJGH_01093 334390.LAF_0520 4.2e-232 810.4 Lactobacillaceae cshB GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 1TPAP@1239,3F4FQ@33958,4HA98@91061,COG0513@1,COG0513@2 NA|NA|NA JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures KIAJIJGH_01094 334390.LAF_0521 0.0 1754.2 Lactobacillaceae alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPK6@1239,3F3QS@33958,4H9XC@91061,COG0013@1,COG0013@2 NA|NA|NA J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain KIAJIJGH_01095 334390.LAF_0522 1.2e-42 178.7 Lactobacillaceae yrzL Bacteria 1VAC4@1239,3F7EG@33958,4HKD0@91061,COG4472@1,COG4472@2 NA|NA|NA S Belongs to the UPF0297 family KIAJIJGH_01096 334390.LAF_0523 9.6e-74 282.7 Lactobacillaceae yqgF GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 ko:K07447 ko00000,ko01000 Bacteria 1V6ER@1239,3F6NI@33958,4HH04@91061,COG0816@1,COG0816@2 NA|NA|NA J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA KIAJIJGH_01097 334390.LAF_0524 5.7e-33 146.7 Lactobacillaceae yrzB Bacteria 1VAPW@1239,3F6X3@33958,4HKV7@91061,COG3906@1,COG3906@2 NA|NA|NA S Belongs to the UPF0473 family KIAJIJGH_01098 334390.LAF_0525 1.6e-163 582.0 Lactobacillaceae rnhC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470,ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Bacteria 1TQBE@1239,3F3TJ@33958,4H9QR@91061,COG1039@1,COG1039@2 NA|NA|NA L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids KIAJIJGH_01099 334390.LAF_0526 4e-90 337.4 Lactobacillaceae cvpA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 ko:K03558 ko00000 Bacteria 1V7U0@1239,3F643@33958,4HIUU@91061,COG1286@1,COG1286@2 NA|NA|NA S Colicin V production protein KIAJIJGH_01100 334390.LAF_0527 0.0 1457.6 Lactobacillaceae mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Bacteria 1TP5W@1239,3F4DX@33958,4H9NZ@91061,COG1193@1,COG1193@2 NA|NA|NA L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity KIAJIJGH_01101 334390.LAF_0528 1e-53 215.7 Lactobacillaceae trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 1VA3Y@1239,3F6Y3@33958,4HKKX@91061,COG3118@1,COG3118@2 NA|NA|NA O Belongs to the thioredoxin family KIAJIJGH_01102 334390.LAF_0529 1.2e-225 788.9 Lactobacillaceae clcA_2 ko:K03281 ko00000 2.A.49 Bacteria 1V07H@1239,3F4QW@33958,4IQYS@91061,COG0038@1,COG0038@2 NA|NA|NA P Chloride transporter, ClC family KIAJIJGH_01103 334390.LAF_0530 1.6e-94 352.1 Lactobacillaceae yslB Bacteria 1VD7N@1239,3F7ZI@33958,4HKV3@91061,COG1719@1,COG1719@2 NA|NA|NA S Protein of unknown function (DUF2507) KIAJIJGH_01104 334390.LAF_0531 1.2e-146 525.8 Lactobacillaceae murI GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 iYO844.BSU28390 Bacteria 1TPPR@1239,3F446@33958,4HA46@91061,COG0796@1,COG0796@2 NA|NA|NA M Provides the (R)-glutamate required for cell wall biosynthesis KIAJIJGH_01105 334390.LAF_0532 3.6e-108 397.5 Lactobacillaceae rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 Bacteria 1V6RN@1239,3F3KD@33958,4HCP6@91061,COG0127@1,COG0127@2 NA|NA|NA F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions KIAJIJGH_01106 334390.LAF_0533 1.4e-95 355.5 Lactobacillaceae ko:K07095 ko00000 Bacteria 1VA0U@1239,3F73R@33958,4HM24@91061,COG0622@1,COG0622@2 NA|NA|NA S Phosphoesterase KIAJIJGH_01107 334390.LAF_0534 1.4e-150 538.9 Lactobacillaceae 3.1.3.102,3.1.3.104,3.1.3.23 ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00548,R00804,R07280 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1UYU8@1239,3F5E3@33958,4HE0K@91061,COG0561@1,COG0561@2 NA|NA|NA S haloacid dehalogenase-like hydrolase KIAJIJGH_01108 334390.LAF_0535 4e-156 557.4 Lactobacillaceae ykuT GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0042802,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 ko:K22044 ko00000,ko02000 1.A.23.3 Bacteria 1TR9Z@1239,3F49U@33958,4HCB8@91061,COG0668@1,COG0668@2 NA|NA|NA M mechanosensitive ion channel KIAJIJGH_01109 334390.LAF_0536 9.2e-26 123.2 Lactobacillaceae WQ51_05790 Bacteria 1VAXN@1239,3F6KB@33958,4HM93@91061,COG4768@1,COG4768@2 NA|NA|NA S protein containing a divergent version of the methyl-accepting chemotaxis-like domain KIAJIJGH_01110 334390.LAF_0537 4.9e-70 270.4 Lactobacillaceae Bacteria 1U6NM@1239,2DKRN@1,30AH6@2,3F87G@33958,4IGFK@91061 NA|NA|NA KIAJIJGH_01111 334390.LAF_0538 2e-213 748.0 Lactobacillaceae pepQ 3.4.13.9 ko:K01271 ko00000,ko01000,ko01002 Bacteria 1TQ6R@1239,3F3X5@33958,4HA5I@91061,COG0006@1,COG0006@2 NA|NA|NA E Creatinase/Prolidase N-terminal domain KIAJIJGH_01112 334390.LAF_0539 2.2e-185 654.8 Lactobacillaceae ccpA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K02529 ko00000,ko03000 Bacteria 1TQ7K@1239,3F4AA@33958,4H9NG@91061,COG1609@1,COG1609@2 NA|NA|NA K catabolite control protein A KIAJIJGH_01113 334390.LAF_0540 3.6e-85 321.6 Lactobacillaceae Bacteria 1W6BV@1239,28T2R@1,2ZFBY@2,3F7CC@33958,4HZQK@91061 NA|NA|NA KIAJIJGH_01114 334390.LAF_0541 3.7e-134 484.2 Lactobacillaceae yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 Bacteria 1TPP5@1239,3F4WF@33958,4H9WJ@91061,COG0217@1,COG0217@2 NA|NA|NA K Transcriptional regulatory protein KIAJIJGH_01115 334390.LAF_0542 9.2e-83 313.9 Lactobacillaceae mltD ko:K08307,ko:K12204,ko:K19224,ko:K21471 ko00000,ko01000,ko01002,ko01011,ko02044 3.A.7.10.1,3.A.7.9.1 CBM50 Bacteria 1VFKC@1239,3F6HG@33958,4IFHN@91061,COG0791@1,COG0791@2,COG1388@1,COG1388@2 NA|NA|NA M PFAM NLP P60 protein KIAJIJGH_01116 334390.LAF_0543 0.0 1109.4 Lactobacillaceae ykcB Bacteria 1TPGI@1239,3F5B1@33958,4HCEY@91061,COG1807@1,COG1807@2 NA|NA|NA M Dolichyl-phosphate-mannose-protein mannosyltransferase KIAJIJGH_01117 334390.LAF_0544 7.7e-177 626.3 Lactobacillaceae comGA ko:K02243 M00429 ko00000,ko00002,ko02044 3.A.14.1 Bacteria 1TPGE@1239,3F4HY@33958,4HB0C@91061,COG2804@1,COG2804@2 NA|NA|NA NU Type II IV secretion system protein KIAJIJGH_01118 334390.LAF_0545 7.1e-160 570.1 Lactobacillaceae comGB ko:K02244 M00429 ko00000,ko00002,ko02044 3.A.14.1 Bacteria 1U00C@1239,3F3S9@33958,4HGUA@91061,COG1459@1,COG1459@2 NA|NA|NA NU type II secretion system KIAJIJGH_01120 349123.Lreu23DRAFT_5009 6e-54 217.2 Lactobacillaceae Bacteria 1TRSF@1239,3F4DZ@33958,4HCMP@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair KIAJIJGH_01121 1567453.A0A0A1EN85_9CAUD 6.6e-65 253.8 Siphoviridae Viruses 4QAJ1@10239,4QM2H@10699,4QPE2@28883 NA|NA|NA S aminoacyl-tRNA ligase activity KIAJIJGH_01122 1567453.A0A0A1ELG8_9CAUD 3.9e-119 434.5 Siphoviridae Viruses 4QF51@10239,4QM5F@10699,4QSYD@28883 NA|NA|NA KIAJIJGH_01123 1567453.A0A0A1ER91_9CAUD 2.9e-42 177.9 Siphoviridae Viruses 4QBCW@10239,4QKNA@10699,4QPS7@28883 NA|NA|NA S Phage gp6-like head-tail connector protein KIAJIJGH_01124 568703.LGG_01131 2.4e-18 98.2 Lactobacillaceae Bacteria 1VIHK@1239,2E86K@1,332JW@2,3F8A2@33958,4HZJB@91061 NA|NA|NA KIAJIJGH_01125 1567453.A0A0A1ENQ3_9CAUD 6e-41 173.3 Siphoviridae Viruses 4QB1F@10239,4QKPW@10699,4QPSW@28883 NA|NA|NA S exonuclease activity KIAJIJGH_01126 1567453.A0A0A1EN91_9CAUD 1.2e-43 182.6 Siphoviridae GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019058,GO:0019068,GO:0044403,GO:0044419,GO:0044423,GO:0051704,GO:0098003,GO:0098004,GO:0098015 Viruses 4QB3I@10239,4QKP4@10699,4QPE3@28883 NA|NA|NA KIAJIJGH_01127 1567453.A0A0A1ELH3_9CAUD 8.1e-84 316.6 Siphoviridae Viruses 4QAVQ@10239,4QKPR@10699,4QPGB@28883 NA|NA|NA S Phage major tail protein 2 KIAJIJGH_01128 1567453.A0A0A1ER95_9CAUD 9.9e-39 166.0 Siphoviridae Viruses 4QBPH@10239,4QKQD@10699,4QQHY@28883 NA|NA|NA S Pfam:Phage_TAC_12 KIAJIJGH_01129 1567453.A0A0A1ENQ9_9CAUD 8.4e-164 584.7 Siphoviridae Viruses 4QAK6@10239,4QKKV@10699,4QPBY@28883 NA|NA|NA S peptidoglycan catabolic process KIAJIJGH_01130 1567453.A0A0A1EN95_9CAUD 4.2e-64 251.5 Siphoviridae GO:0005575,GO:0019012,GO:0044423,GO:0098015 Viruses 4QBF8@10239,4QKN2@10699,4QPI9@28883 NA|NA|NA S Phage tail protein KIAJIJGH_01131 1567453.A0A0A1ELH9_9CAUD 3.8e-223 782.3 Siphoviridae Viruses 4QAK6@10239,4QKKV@10699,4QPBY@28883 NA|NA|NA S peptidoglycan catabolic process KIAJIJGH_01134 349123.Lreu23DRAFT_4194 1e-20 106.7 Lactobacillaceae Bacteria 1VJPW@1239,2EES0@1,338JP@2,3F70J@33958,4HPSW@91061 NA|NA|NA S Bacteriophage holin family KIAJIJGH_01135 349123.Lreu23DRAFT_4193 9.8e-124 449.9 Bacteria Bacteria COG3757@1,COG3757@2 NA|NA|NA M lysozyme activity KIAJIJGH_01136 1305737.JAFX01000001_gene2507 1e-103 383.6 Bacteroidetes 2.1.1.72 ko:K00571 ko00000,ko01000,ko02048 Bacteria 2DB9A@1,2Z7VI@2,4NJ4U@976 NA|NA|NA S Psort location Cytoplasmic, score 8.96 KIAJIJGH_01137 537011.PREVCOP_06739 5.6e-137 494.2 Bacteroidia Bacteria 2FQXX@200643,4NGH2@976,COG1403@1,COG1403@2,COG1479@1,COG1479@2 NA|NA|NA L Psort location Cytoplasmic, score KIAJIJGH_01138 334390.LAF_0546 1.4e-38 165.2 Lactobacillaceae comGC GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 ko:K02245,ko:K02456 ko03070,ko05111,map03070,map05111 M00331,M00429 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 1VFI9@1239,3F7ZC@33958,4HNNT@91061,COG4537@1,COG4537@2 NA|NA|NA U competence protein ComGC KIAJIJGH_01139 557436.Lreu_0556 2.3e-15 89.0 Lactobacillaceae ko:K02246,ko:K02456,ko:K02457,ko:K02679 ko03070,ko05111,map03070,map05111 M00331,M00429 ko00000,ko00001,ko00002,ko02044 3.A.15 Bacteria 1U6NU@1239,3F87R@33958,4IGFS@91061,COG2165@1,COG2165@2 NA|NA|NA NU general secretion pathway protein KIAJIJGH_01141 349123.Lreu23DRAFT_3620 3.8e-14 84.7 Lactobacillaceae ko:K02248 M00429 ko00000,ko00002,ko02044 Bacteria 1W67R@1239,2DGNT@1,2ZWQN@2,3F85R@33958,4I06G@91061 NA|NA|NA KIAJIJGH_01143 334390.LAF_0549 1e-159 569.3 Lactobacillaceae ytxK 2.1.1.72 ko:K00571 ko00000,ko01000,ko02048 Bacteria 1TRIQ@1239,3F4CI@33958,4H9SE@91061,COG0827@1,COG0827@2 NA|NA|NA L N-6 DNA Methylase KIAJIJGH_01144 334390.LAF_0550 9.5e-225 785.8 Lactobacillaceae ackA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv0409 Bacteria 1TQ22@1239,3F48Z@33958,4HA7K@91061,COG0282@1,COG0282@2 NA|NA|NA F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction KIAJIJGH_01145 334390.LAF_0551 5.3e-110 403.7 Lactobacillaceae Bacteria 1V40Y@1239,3F4EX@33958,4HH4J@91061,COG4186@1,COG4186@2 NA|NA|NA S Calcineurin-like phosphoesterase KIAJIJGH_01146 334390.LAF_0552 1.2e-97 362.5 Lactobacillaceae yutD Bacteria 1VA85@1239,3F66P@33958,4HKF7@91061,COG4470@1,COG4470@2 NA|NA|NA S Protein of unknown function (DUF1027) KIAJIJGH_01147 334390.LAF_0553 6.6e-142 510.0 Lactobacillaceae nagD 2.7.1.25,3.1.3.41 ko:K00860,ko:K01101 ko00230,ko00627,ko00920,ko01100,ko01120,map00230,map00627,map00920,map01100,map01120 M00176 R00509,R03024,R04928 RC00002,RC00078,RC00151 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQGM@1239,3F49D@33958,4HA3R@91061,COG0647@1,COG0647@2 NA|NA|NA G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro KIAJIJGH_01148 349123.Lreu23DRAFT_3627 9.8e-25 120.6 Lactobacillaceae Bacteria 1V7UW@1239,3F4YP@33958,4HHH4@91061,COG4478@1,COG4478@2 NA|NA|NA S Protein of unknown function (DUF1461) KIAJIJGH_01149 334390.LAF_0554 1.9e-102 378.6 Lactobacillaceae dedA ko:K03975 ko00000 Bacteria 1UZ4P@1239,3F4KG@33958,4HG3F@91061,COG0586@1,COG0586@2 NA|NA|NA S SNARE-like domain protein KIAJIJGH_01150 438780.D2KRD2_9CAUD 4.8e-183 647.5 Siphoviridae Viruses 4QBIH@10239,4QM8U@10699,4QPU0@28883,4QVPB@35237 NA|NA|NA S Recombinase KIAJIJGH_01151 947980.E9LUL0_9CAUD 3.8e-56 224.6 Siphoviridae Viruses 4QE6D@10239,4QMJS@10699,4QR0Q@28883,4QV9U@35237 NA|NA|NA KIAJIJGH_01152 334390.LAF_0658 4.1e-101 374.4 Lactobacillaceae kcsA GO:0003674,GO:0005215,GO:0005216,GO:0005244,GO:0005249,GO:0005261,GO:0005267,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022832,GO:0022836,GO:0022838,GO:0022839,GO:0022843,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 ko:K10716 ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 Bacteria 1V285@1239,3F64X@33958,4I17E@91061,COG1226@1,COG1226@2 NA|NA|NA P Ion transport protein KIAJIJGH_01153 1423814.HMPREF0549_1751 2.1e-24 118.6 Lactobacillaceae xkdA Bacteria 1W1K0@1239,3F81Z@33958,4IGCD@91061,COG2856@1,COG2856@2 NA|NA|NA E Zn peptidase KIAJIJGH_01154 1122147.AUEH01000006_gene1798 5.8e-18 97.1 Bacilli 3.4.21.88 ko:K01356 M00729 ko00000,ko00002,ko01000,ko01002,ko03400 Bacteria 1VJV9@1239,4HJXB@91061,COG1974@1,COG1974@2 NA|NA|NA K Helix-turn-helix KIAJIJGH_01155 1423775.BAMN01000009_gene433 6.5e-08 63.2 Lactobacillaceae cro Bacteria 1U73I@1239,3F8XM@33958,4IGY4@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins KIAJIJGH_01156 334390.LAF_0661 9.1e-112 409.8 Firmicutes ko:K07741 ko00000 Bacteria 1V8V3@1239,COG3646@1,COG3646@2 NA|NA|NA K Phage regulatory protein KIAJIJGH_01160 334390.LAF_0663 5e-24 116.3 Lactobacillaceae Bacteria 1U72W@1239,29PV4@1,30ATA@2,3F8WK@33958,4IGXE@91061 NA|NA|NA KIAJIJGH_01161 334390.LAF_0664 1.5e-33 148.3 Lactobacillaceae Bacteria 1VG7Y@1239,2E3GE@1,32YF6@2,3F8YH@33958,4HYAR@91061 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2188) KIAJIJGH_01162 1545701.LACWKB10_1149 2.5e-10 71.6 Lactobacillaceae Bacteria 1U6KQ@1239,29PHI@1,30AFP@2,3F840@33958,4IGDG@91061 NA|NA|NA S Domain of unknown function (DUF771) KIAJIJGH_01166 334390.LAF_0667 1.4e-149 535.8 Lactobacillaceae recT ko:K07455 ko00000,ko03400 Bacteria 1V0QW@1239,3F47A@33958,4HBS2@91061,COG3723@1,COG3723@2 NA|NA|NA L RecT family KIAJIJGH_01167 334390.LAF_0668 4.2e-150 537.3 Lactobacillaceae pi112 3.6.4.12 ko:K03657,ko:K16898 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1V1UQ@1239,3F51S@33958,4HGSG@91061,COG1074@1,COG1074@2 NA|NA|NA L PDDEXK-like domain of unknown function (DUF3799) KIAJIJGH_01168 334390.LAF_0669 7.6e-94 349.7 Lactobacillaceae ssb_2 ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 1V3WT@1239,3F66N@33958,4HH8I@91061,COG0629@1,COG0629@2 NA|NA|NA L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism KIAJIJGH_01169 557436.Lreu_0813 9e-26 124.0 Lactobacillaceae Bacteria 1TPPF@1239,3F7TX@33958,4HNK6@91061,COG3935@1,COG3935@2 NA|NA|NA L Psort location Cytoplasmic, score KIAJIJGH_01176 1605.Lani381_0855 3.5e-10 70.9 Lactobacillaceae ko:K07474 ko00000 Bacteria 1VAD9@1239,3F6ZJ@33958,4HXMG@91061,COG3728@1,COG3728@2 NA|NA|NA L Terminase small subunit KIAJIJGH_01178 349123.Lreu23DRAFT_4213 1.2e-189 669.1 Lactobacillaceae ko:K06909 ko00000 Bacteria 1TRQP@1239,3FB8E@33958,4HDMY@91061,COG1783@1,COG1783@2 NA|NA|NA S Phage terminase, large subunit KIAJIJGH_01179 1567453.A0A0A1ER87_9CAUD 6.5e-209 733.4 Siphoviridae GO:0005575,GO:0019012,GO:0019028,GO:0032991,GO:0044423,GO:0046729,GO:0046798 Viruses 4QAR7@10239,4QKQ3@10699,4QPKJ@28883 NA|NA|NA S Phage portal protein, SPP1 Gp6-like KIAJIJGH_01180 1567453.A0A0A1EKX3_9CAUD 3.1e-136 491.5 Siphoviridae GO:0005575,GO:0019012,GO:0019028,GO:0044423,GO:0046729 Viruses 4QC5Z@10239,4QKMB@10699,4QPGX@28883 NA|NA|NA S Phage Mu protein F like protein KIAJIJGH_01181 1114972.AUAW01000027_gene734 7.3e-71 273.1 Lactobacillaceae dapA 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCK@1239,3F4UH@33958,4H9K9@91061,COG0329@1,COG0329@2 NA|NA|NA E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) KIAJIJGH_01182 585524.HMPREF0493_1660 3.5e-10 70.1 Lactobacillaceae Bacteria 1U7RF@1239,2AJCU@1,30B90@2,3FA2F@33958,4IHNT@91061 NA|NA|NA S Homeodomain-like domain KIAJIJGH_01183 1203076.CAKF01000021_gene1477 1.3e-121 442.6 Lactobacillaceae Bacteria 1TRQC@1239,3F4FH@33958,4HD7P@91061,COG1028@1,COG1028@2 NA|NA|NA IQ reductase KIAJIJGH_01186 1423780.LOT_0235 2.4e-17 94.0 Lactobacillaceae rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 ko:K02911 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1VKMZ@1239,3F7ZT@33958,4HR2Q@91061,COG0333@1,COG0333@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL32 family KIAJIJGH_01191 349123.Lreu23DRAFT_3295 1.1e-128 466.8 Lactobacillaceae Bacteria 1TSH6@1239,3F5HS@33958,4HEX8@91061,COG3385@1,COG3385@2 NA|NA|NA L PFAM transposase, IS4 family protein KIAJIJGH_01192 334390.LAF_1175 6.6e-260 902.9 Lactobacillaceae nylA 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 Bacteria 1TPGJ@1239,3F4UM@33958,4HBE7@91061,COG0154@1,COG0154@2 NA|NA|NA J Belongs to the amidase family KIAJIJGH_01193 334390.LAF_1176 5.6e-128 463.8 Lactobacillaceae arcD Bacteria 1TQJ0@1239,3F4C3@33958,4H9P7@91061,COG1288@1,COG1288@2 NA|NA|NA S C4-dicarboxylate anaerobic carrier KIAJIJGH_01194 334390.LAF_1177 1.9e-214 751.5 Lactobacillaceae rlmL GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016423,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 ko:K07444,ko:K12297 R07234 RC00003 ko00000,ko01000,ko03009 Bacteria 1TP0X@1239,3F3NZ@33958,4HBKY@91061,COG0116@1,COG0116@2 NA|NA|NA L Belongs to the methyltransferase superfamily KIAJIJGH_01195 334390.LAF_1178 4.4e-82 310.5 Lactobacillaceae Bacteria 1V6X2@1239,3FBFE@33958,4IQ2D@91061,COG1051@1,COG1051@2 NA|NA|NA F Hydrolase, NUDIX family KIAJIJGH_01196 334390.LAF_1179 4.7e-213 746.9 Lactobacillaceae ko:K06915 ko00000 Bacteria 1UA9I@1239,3F409@33958,4HUCP@91061,COG0433@1,COG0433@2 NA|NA|NA S Type IV secretion-system coupling protein DNA-binding domain KIAJIJGH_01197 334390.LAF_1180 4.5e-171 607.1 Lactobacillaceae tetP ko:K02355 ko00000,ko03012,ko03029 Bacteria 1TPQH@1239,3F4B4@33958,4HAS9@91061,COG0480@1,COG0480@2 NA|NA|NA J elongation factor G KIAJIJGH_01198 334390.LAF_1181 4.6e-58 230.3 Lactobacillaceae gpsB ko:K04074 ko00000,ko03036 Bacteria 1VEQ4@1239,3F6VZ@33958,4HNP1@91061,COG3599@1,COG3599@2 NA|NA|NA D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation KIAJIJGH_01199 334390.LAF_1182 6e-111 406.8 Lactobacillaceae ypsA Bacteria 1V6SM@1239,3F4MR@33958,4HJGM@91061,COG4474@1,COG4474@2 NA|NA|NA S Belongs to the UPF0398 family KIAJIJGH_01200 334390.LAF_1183 4.6e-117 427.2 Lactobacillaceae recU GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 ko:K03700 ko00000,ko03400 Bacteria 1V3S4@1239,3F4DG@33958,4HGZ7@91061,COG3331@1,COG3331@2 NA|NA|NA L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation KIAJIJGH_01201 334390.LAF_1184 0.0 1299.3 Lactobacillaceae ponA GO:0005575,GO:0005576 2.4.1.129,3.4.16.4 ko:K05365,ko:K05366,ko:K12555,ko:K21464 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 1TPM5@1239,3F424@33958,4H9SA@91061,COG0744@1,COG0744@2 NA|NA|NA M penicillin-binding protein 1A KIAJIJGH_01202 334390.LAF_1185 3.7e-160 570.9 Lactobacillaceae Bacteria 1TR6G@1239,3F423@33958,4HAMD@91061,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family KIAJIJGH_01203 334390.LAF_1186 1.8e-192 678.3 Lactobacillaceae ko:K19265 ko00000,ko01000 Bacteria 1TRS0@1239,3F414@33958,4HAZ2@91061,COG0667@1,COG0667@2 NA|NA|NA C Aldo keto reductase family protein KIAJIJGH_01204 334390.LAF_1187 1.3e-121 443.0 Lactobacillaceae ypuA Bacteria 1TR2I@1239,3FBNF@33958,4HBVZ@91061,COG4086@1,COG4086@2 NA|NA|NA S Protein of unknown function (DUF1002) KIAJIJGH_01205 334390.LAF_1188 2e-132 478.4 Lactobacillaceae dnaD ko:K02086 ko00000 Bacteria 1V283@1239,3F4FF@33958,4HFP3@91061,COG3935@1,COG3935@2 NA|NA|NA L DnaD domain protein KIAJIJGH_01206 334390.LAF_1189 2.1e-257 894.4 Lactobacillaceae asnS GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP38@1239,3F4EK@33958,4H9YH@91061,COG0017@1,COG0017@2 NA|NA|NA J Asparaginyl-tRNA synthetase KIAJIJGH_01207 334390.LAF_1190 1.6e-88 332.0 Lactobacillaceae ypmB Bacteria 1VA2H@1239,3F4MM@33958,4HNMM@91061,COG5353@1,COG5353@2 NA|NA|NA S Protein conserved in bacteria KIAJIJGH_01208 334390.LAF_1191 0.0 1829.3 Lactobacillaceae dinG GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7,3.6.4.12 ko:K02342,ko:K03722 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TQHQ@1239,3F4KA@33958,4HB2Y@91061,COG0847@1,COG0847@2,COG1199@1,COG1199@2 NA|NA|NA L helicase involved in DNA repair and perhaps also replication KIAJIJGH_01209 324831.LGAS_1468 1.8e-45 190.3 Bacilli Bacteria 1V45J@1239,2DEV0@1,2ZPCC@2,4IREU@91061 NA|NA|NA KIAJIJGH_01211 1423814.HMPREF0549_1444 7.7e-12 75.9 Lactobacillaceae Bacteria 1VH48@1239,2CI33@1,3347K@2,3F7UP@33958,4IG8B@91061 NA|NA|NA KIAJIJGH_01212 1423814.HMPREF0549_1443 2.9e-11 74.7 Lactobacillaceae Bacteria 1UFAR@1239,2A43N@1,30SNQ@2,3F7I9@33958,4I4IY@91061 NA|NA|NA KIAJIJGH_01213 575594.ACOH01000006_gene286 2.7e-176 624.8 Lactobacillaceae Bacteria 1TPIC@1239,3F5UA@33958,4HCNN@91061,COG2887@1,COG2887@2 NA|NA|NA L Protein of unknown function (DUF2800) KIAJIJGH_01214 1423814.HMPREF0549_1441 1.5e-84 318.9 Lactobacillaceae Bacteria 1TRF9@1239,28J2E@1,2Z8YX@2,3FCFP@33958,4HHVK@91061 NA|NA|NA S Protein of unknown function (DUF2815) KIAJIJGH_01215 575594.ACOH01000006_gene284 5.9e-301 1039.6 Lactobacillaceae polA_2 2.7.7.7 ko:K02334,ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 1TPTJ@1239,3F5VV@33958,4H9Z7@91061,COG0749@1,COG0749@2 NA|NA|NA L DNA polymerase KIAJIJGH_01216 575594.ACOH01000006_gene283 6.7e-42 176.8 Lactobacillaceae Bacteria 1V7Z1@1239,2CGYE@1,31NJV@2,3F6P6@33958,4HI04@91061 NA|NA|NA S Psort location Cytoplasmic, score KIAJIJGH_01217 324831.LGAS_1475 0.0 1173.7 Lactobacillaceae ko:K06919 ko00000 Bacteria 1TQP9@1239,3F3UD@33958,4HBTB@91061,COG3378@1,COG3378@2 NA|NA|NA S Phage plasmid primase, P4 KIAJIJGH_01218 575594.ACOH01000006_gene281 5.8e-40 169.9 Lactobacillaceae Bacteria 1VAXK@1239,2E38J@1,32Y88@2,3F791@33958,4HNXW@91061 NA|NA|NA S VRR_NUC KIAJIJGH_01219 575594.ACOH01000006_gene280 1.7e-225 788.5 Lactobacillaceae Bacteria 1TPFZ@1239,3FCEQ@33958,4H9YP@91061,COG0553@1,COG0553@2 NA|NA|NA L SNF2 family N-terminal domain KIAJIJGH_01220 1423814.HMPREF0549_1434 2e-45 188.7 Lactobacillaceae Bacteria 1V1Z3@1239,2A2FF@1,30QSJ@2,3F52R@33958,4IEZ7@91061 NA|NA|NA KIAJIJGH_01221 525309.HMPREF0494_0893 1.4e-57 228.8 Bacilli ko:K07451 ko00000,ko01000,ko02048 Bacteria 1V7XZ@1239,4HHQB@91061,COG1403@1,COG1403@2 NA|NA|NA V HNH nucleases KIAJIJGH_01222 324831.LGAS_1479 1.4e-77 295.4 Lactobacillaceae Bacteria 1TV6T@1239,28IR9@1,2Z8QS@2,3F5G5@33958,4HCA9@91061 NA|NA|NA KIAJIJGH_01223 326425.lhe_1027 2.1e-42 177.9 Lactobacillaceae yefM 2.3.1.15 ko:K08591,ko:K19158,ko:K19159 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004,ko02048 Bacteria 1U6CD@1239,3F7KJ@33958,4IG41@91061,COG2161@1,COG2161@2 NA|NA|NA D Antitoxin component of a toxin-antitoxin (TA) module KIAJIJGH_01224 525309.HMPREF0494_0891 7.3e-188 663.3 Lactobacillaceae 2.1.1.72 ko:K07319 ko00000,ko01000,ko02048 Bacteria 1TPHP@1239,3F5AA@33958,4HC9M@91061,COG0863@1,COG0863@2,COG1475@1,COG1475@2 NA|NA|NA KL DNA methylase KIAJIJGH_01225 575594.ACOH01000006_gene275 1.7e-52 212.6 Lactobacillaceae Bacteria 1V25Y@1239,2948F@1,2ZRNR@2,3F5VX@33958,4HEHF@91061 NA|NA|NA S Psort location Cytoplasmic, score KIAJIJGH_01226 525309.HMPREF0494_0889 4.2e-11 73.6 Lactobacillaceae Bacteria 1U5J7@1239,2DKJR@1,309R8@2,3F7H0@33958,4IG29@91061 NA|NA|NA S Domain of unknown function (DUF5049) KIAJIJGH_01227 525309.HMPREF0494_0888 4.6e-296 1023.1 Lactobacillaceae Bacteria 1TPU1@1239,3F51U@33958,4HAXI@91061,COG4626@1,COG4626@2 NA|NA|NA S overlaps another CDS with the same product name KIAJIJGH_01228 575605.ACQN01000003_gene469 8.2e-36 156.0 Lactobacillaceae Bacteria 1U6QV@1239,3F8BU@33958,4IGI5@91061,COG2002@1,COG2002@2 NA|NA|NA K Antidote-toxin recognition MazE, bacterial antitoxin KIAJIJGH_01230 713605.ADHG01000006_gene764 1.4e-40 172.6 Lactobacillaceae Bacteria 1VD10@1239,3F6QC@33958,4HMF3@91061,COG3279@1,COG3279@2 NA|NA|NA K LytTr DNA-binding domain KIAJIJGH_01231 713605.ADHG01000006_gene765 3.6e-28 131.3 Lactobacillaceae Bacteria 1VHBQ@1239,2E0UI@1,32WBZ@2,3F7MD@33958,4IR8K@91061 NA|NA|NA S Protein of unknown function (DUF3021) KIAJIJGH_01232 324831.LGAS_1483 1.2e-238 832.0 Lactobacillaceae Bacteria 1TP8B@1239,3F42D@33958,4HHWD@91061,COG4695@1,COG4695@2 NA|NA|NA S Phage portal protein KIAJIJGH_01233 324831.LGAS_1484 1.8e-111 408.7 Lactobacillaceae clpP 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Bacteria 1TR2H@1239,3F5E9@33958,4HBZH@91061,COG0740@1,COG0740@2 NA|NA|NA OU Belongs to the peptidase S14 family KIAJIJGH_01234 324831.LGAS_1485 2.3e-207 728.0 Lactobacillaceae Bacteria 1TS6A@1239,3F4Y2@33958,4HCCS@91061,COG4653@1,COG4653@2 NA|NA|NA S Phage capsid family KIAJIJGH_01235 575594.ACOH01000006_gene269 1.8e-41 174.9 Lactobacillaceae Bacteria 1VETG@1239,2E3C8@1,32YBI@2,3FA1K@33958,4IS2S@91061 NA|NA|NA S Phage gp6-like head-tail connector protein KIAJIJGH_01236 525309.HMPREF0494_0883 7.6e-67 259.6 Lactobacillaceae Bacteria 1VBQZ@1239,3F6FJ@33958,4IFGX@91061,COG5614@1,COG5614@2 NA|NA|NA S Phage head-tail joining protein KIAJIJGH_01237 525309.HMPREF0494_0882 3.8e-67 260.8 Lactobacillaceae Bacteria 1V3TR@1239,3F68Y@33958,4IRAT@91061,COG4824@1,COG4824@2 NA|NA|NA S Bacteriophage holin family KIAJIJGH_01238 324831.LGAS_1488 1.3e-133 482.6 Lactobacillaceae ko:K07273 ko00000 Bacteria 1V1TE@1239,3F5T1@33958,4I2AF@91061,COG3023@1,COG3023@2,COG3757@1,COG3757@2 NA|NA|NA M Glycosyl hydrolases family 25 KIAJIJGH_01239 349123.Lreu23DRAFT_4347 1.8e-26 124.8 Lactobacillaceae Bacteria 1U69K@1239,2DKP9@1,30A6N@2,3F7DG@33958,4IG0R@91061 NA|NA|NA KIAJIJGH_01240 575594.ACOH01000006_gene265 3.1e-274 950.7 Lactobacillaceae Bacteria 1TPBH@1239,3F4SH@33958,4IQ08@91061,COG1961@1,COG1961@2 NA|NA|NA L Recombinase zinc beta ribbon domain KIAJIJGH_01241 525309.HMPREF0494_0878 3.2e-270 937.2 Lactobacillaceae ko:K06400 ko00000 Bacteria 1TPBH@1239,3FCES@33958,4HD54@91061,COG1961@1,COG1961@2 NA|NA|NA L Recombinase KIAJIJGH_01242 543734.LCABL_29970 1.8e-69 270.0 Lactobacillaceae Bacteria 1UYYR@1239,3F7XH@33958,4HHVE@91061,COG2865@1,COG2865@2 NA|NA|NA K Putative DNA-binding domain KIAJIJGH_01243 334390.LAF_1469 5.8e-258 896.3 Lactobacillaceae rumA GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 ko:K03215 ko00000,ko01000,ko03009 Bacteria 1TP4H@1239,3F41R@33958,4HA6M@91061,COG2265@1,COG2265@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family KIAJIJGH_01244 334390.LAF_1470 1.9e-186 658.3 Lactobacillaceae yegS GO:0001727,GO:0003674,GO:0003824,GO:0004143,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0030258,GO:0044237,GO:0044238,GO:0044255,GO:0046834,GO:0071704 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 R02240 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TQAU@1239,3F447@33958,4H9WD@91061,COG1597@1,COG1597@2 NA|NA|NA G Lipid kinase KIAJIJGH_01245 334390.LAF_1471 5e-273 946.4 Lactobacillaceae gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 ko:K01876,ko:K02434 ko00970,ko01100,map00970,map01100 M00359,M00360 R03905,R04212,R05577 RC00010,RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TPG3@1239,3F44H@33958,4HAFB@91061,COG0064@1,COG0064@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) KIAJIJGH_01246 334390.LAF_1472 2.2e-271 941.0 Lactobacillaceae gatA 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 Bacteria 1TP0C@1239,3F4BK@33958,4HBAZ@91061,COG0154@1,COG0154@2 NA|NA|NA J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) KIAJIJGH_01247 334390.LAF_1473 6e-49 199.9 Lactobacillaceae gatC 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 iAF987.Gmet_0076 Bacteria 1VEK3@1239,3F7XB@33958,4HNNA@91061,COG0721@1,COG0721@2 NA|NA|NA J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) KIAJIJGH_01248 334390.LAF_1474 9.4e-153 547.0 Lactobacillaceae camS Bacteria 1TSYE@1239,3F3KI@33958,4HBI8@91061,COG4851@1,COG4851@2 NA|NA|NA S sex pheromone KIAJIJGH_01249 334390.LAF_1475 0.0 1326.2 Lactobacillaceae ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 1TPQ3@1239,3F43C@33958,4HA1D@91061,COG0272@1,COG0272@2 NA|NA|NA L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA KIAJIJGH_01250 334390.LAF_1476 0.0 1427.5 Lactobacillaceae pcrA 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPSU@1239,3F400@33958,4HB12@91061,COG0210@1,COG0210@2 NA|NA|NA L ATP-dependent DNA helicase KIAJIJGH_01251 334390.LAF_1477 1.4e-220 771.9 Lactobacillaceae purK2 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQCD@1239,3FC8U@33958,4HJI4@91061,COG0026@1,COG0026@2 NA|NA|NA F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate KIAJIJGH_01252 334390.LAF_1478 1.1e-101 375.9 Lactobacillaceae xpt GO:0003674,GO:0003824,GO:0006139,GO:0006166,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046128,GO:0046129,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.22,2.4.2.7 ko:K00759,ko:K03816,ko:K09685 ko00230,ko01100,ko01110,map00230,map01100,map01110 R00190,R01229,R02142,R04378 RC00063,RC00122 ko00000,ko00001,ko01000,ko03000,ko04147 iYO844.BSU22070 Bacteria 1V1DU@1239,3F49S@33958,4HFNW@91061,COG0503@1,COG0503@2 NA|NA|NA F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis KIAJIJGH_01253 334390.LAF_1479 2.2e-108 398.3 Lactobacillaceae acmC 3.2.1.17,3.2.1.96 ko:K01185,ko:K01227,ko:K02395 ko00511,map00511 ko00000,ko00001,ko01000,ko02035 Bacteria 1V7JY@1239,3F584@33958,4HIY4@91061,COG1705@1,COG1705@2 NA|NA|NA NU mannosyl-glycoprotein KIAJIJGH_01254 334390.LAF_1480 1.2e-138 499.2 Lactobacillaceae Bacteria 1TRQC@1239,3F4FH@33958,4HD7P@91061,COG1028@1,COG1028@2 NA|NA|NA IQ reductase KIAJIJGH_01255 334390.LAF_1457 1.6e-178 632.1 Lactobacillaceae ko:K07035 ko00000 Bacteria 1TS5F@1239,3F4FE@33958,4HC7U@91061,COG3641@1,COG3641@2 NA|NA|NA S Phosphotransferase system, EIIC KIAJIJGH_01256 1437606.BBOH_1213 2.1e-23 114.8 Bacteria ko:K19158 ko00000,ko01000,ko02048 Bacteria COG4115@1,COG4115@2 NA|NA|NA D mRNA cleavage KIAJIJGH_01257 1423775.BAMN01000002_gene1909 7.2e-21 106.3 Lactobacillaceae 2.3.1.15 ko:K08591,ko:K19159 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004,ko02048 Bacteria 1VEE5@1239,3F88Y@33958,4HP02@91061,COG2161@1,COG2161@2 NA|NA|NA D Antitoxin component of a toxin-antitoxin (TA) module KIAJIJGH_01258 334390.LAF_1199 4.8e-184 650.2 Lactobacillaceae rsmF GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176,2.1.1.178 ko:K03500,ko:K11392 ko00000,ko01000,ko03009 Bacteria 1TPGQ@1239,3F492@33958,4HCHQ@91061,COG0144@1,COG0144@2,COG3270@1,COG3270@2 NA|NA|NA J NOL1 NOP2 sun family protein KIAJIJGH_01259 1423815.BACR01000027_gene1348 9e-92 343.6 Lactobacillaceae pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TQ5X@1239,3F4ER@33958,4HBEB@91061,COG0226@1,COG0226@2 NA|NA|NA P Phosphate KIAJIJGH_01260 797515.HMPREF9103_01959 2.4e-98 365.5 Lactobacillaceae pstC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02037 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TSPP@1239,3F3NI@33958,4HC9H@91061,COG0573@1,COG0573@2 NA|NA|NA P probably responsible for the translocation of the substrate across the membrane KIAJIJGH_01261 797515.HMPREF9103_01960 1.3e-103 382.9 Lactobacillaceae pstA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02038 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko02000 3.A.1.7 Bacteria 1TP74@1239,3F412@33958,4HAKF@91061,COG0581@1,COG0581@2 NA|NA|NA P Phosphate transport system permease protein PstA KIAJIJGH_01262 334390.LAF_1196 9.5e-96 356.7 Lactobacillaceae pstB 3.6.3.27 ko:K02036 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 iLJ478.TM1261 Bacteria 1TRSF@1239,3F4DZ@33958,4HCMP@91061,COG1117@1,COG1117@2,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair KIAJIJGH_01263 334390.LAF_1195 1.5e-205 721.8 Lactobacillaceae fni 1.1.1.88,5.3.3.2 ko:K00054,ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123,R02081 RC00004,RC00455,RC00644 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQZ3@1239,3F3UY@33958,4HAMV@91061,COG1304@1,COG1304@2 NA|NA|NA C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) KIAJIJGH_01264 334390.LAF_1194 2.4e-62 244.6 Lactobacillaceae mvaK2 2.7.1.36,2.7.1.43,2.7.4.2 ko:K00869,ko:K00938,ko:K16190 ko00040,ko00053,ko00520,ko00900,ko01100,ko01110,ko01130,ko04146,map00040,map00053,map00520,map00900,map01100,map01110,map01130,map04146 M00014,M00095 R01476,R02245,R03245 RC00002,RC00017,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPKP@1239,3F3RZ@33958,4HC93@91061,COG1577@1,COG1577@2 NA|NA|NA I phosphomevalonate kinase KIAJIJGH_01265 334390.LAF_1194 1.4e-97 362.5 Lactobacillaceae mvaK2 2.7.1.36,2.7.1.43,2.7.4.2 ko:K00869,ko:K00938,ko:K16190 ko00040,ko00053,ko00520,ko00900,ko01100,ko01110,ko01130,ko04146,map00040,map00053,map00520,map00900,map01100,map01110,map01130,map04146 M00014,M00095 R01476,R02245,R03245 RC00002,RC00017,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPKP@1239,3F3RZ@33958,4HC93@91061,COG1577@1,COG1577@2 NA|NA|NA I phosphomevalonate kinase KIAJIJGH_01266 334390.LAF_1193 4.1e-167 594.0 Lactobacillaceae mvaD 4.1.1.33 ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R01121 RC00453 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQXR@1239,3F4B5@33958,4HAM6@91061,COG3407@1,COG3407@2 NA|NA|NA I diphosphomevalonate decarboxylase KIAJIJGH_01267 334390.LAF_1125 1.9e-153 548.5 Lactobacillaceae Bacteria 1V8NG@1239,3F41V@33958,4HJ22@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha/beta hydrolase of unknown function (DUF915) KIAJIJGH_01268 334390.LAF_1124 3.1e-275 953.7 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase KIAJIJGH_01269 334390.LAF_1123 0.0 1135.6 Lactobacillaceae yjbQ ko:K03455,ko:K03499 ko00000,ko02000 2.A.37,2.A.38.1,2.A.38.4 Bacteria 1TS32@1239,3F4AZ@33958,4H9Q5@91061,COG0475@1,COG0475@2,COG0569@1,COG0569@2 NA|NA|NA P TrkA C-terminal domain protein KIAJIJGH_01270 334390.LAF_1122 5.4e-26 122.9 Lactobacillaceae dmpI GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 Bacteria 1VKD5@1239,3F83T@33958,4HRBS@91061,COG1942@1,COG1942@2 NA|NA|NA G Belongs to the 4-oxalocrotonate tautomerase family KIAJIJGH_01271 334390.LAF_1121 3.9e-284 983.4 Lactobacillaceae glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 Bacteria 1TPX3@1239,3F3WI@33958,4H9ZF@91061,COG0554@1,COG0554@2 NA|NA|NA F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate KIAJIJGH_01273 334390.LAF_1119 0.0 1320.1 Lactobacillaceae kup GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 ko:K03549 ko00000,ko02000 2.A.72 Bacteria 1TRUQ@1239,3F4CU@33958,4HA8Z@91061,COG3158@1,COG3158@2 NA|NA|NA P Transport of potassium into the cell KIAJIJGH_01274 334390.LAF_1116 0.0 1832.0 Lactobacillaceae Bacteria 1TPVY@1239,3F4AK@33958,4HD9X@91061,COG4485@1,COG4485@2 NA|NA|NA S Bacterial membrane protein YfhO KIAJIJGH_01276 334390.LAF_1114 7.7e-237 826.2 Lactobacillaceae lmrB ko:K18926 M00715 ko00000,ko00002,ko02000 2.A.1.3.30 Bacteria 1TPRN@1239,3F4A2@33958,4H9VV@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily KIAJIJGH_01277 334390.LAF_1113 1.6e-157 562.0 Lactobacillaceae Bacteria 1VSYU@1239,3F4J2@33958,4HU15@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha beta hydrolase KIAJIJGH_01278 334390.LAF_1112 6.6e-159 566.6 Lactobacillaceae 1.6.5.2 ko:K19267 ko00130,ko01110,map00130,map01110 R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 Bacteria 1V0UQ@1239,3FB42@33958,4HDP4@91061,COG0702@1,COG0702@2 NA|NA|NA GM NAD(P)H-binding KIAJIJGH_01279 334390.LAF_1111 1.1e-152 545.8 Lactobacillaceae Bacteria 1UYU8@1239,3FC8A@33958,4HE0K@91061,COG0561@1,COG0561@2 NA|NA|NA S Sucrose-6F-phosphate phosphohydrolase KIAJIJGH_01281 334390.LAF_1110 1.7e-222 778.5 Lactobacillaceae dtpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03305 ko00000 2.A.17 Bacteria 1TP81@1239,3F4WU@33958,4HAF2@91061,COG3104@1,COG3104@2 NA|NA|NA U amino acid peptide transporter KIAJIJGH_01283 334390.LAF_1109 7.1e-212 743.0 Lactobacillaceae ydiN GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0015291,GO:0015292,GO:0016020,GO:0022804,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 Bacteria 1UI3V@1239,3F3ZF@33958,4ISEV@91061,COG2271@1,COG2271@2 NA|NA|NA G Major Facilitator Superfamily KIAJIJGH_01284 1214166.ALLG01000027_gene1135 7.6e-13 79.7 Streptococcus suis pheA GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 1.3.1.12,2.3.1.79,4.2.1.51,5.4.99.5 ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715,R01728 RC00125,RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_2667 Bacteria 1VK50@1239,1WTN3@1307,4HS6M@91061,COG1605@1,COG1605@2 NA|NA|NA E Chorismate mutase type II KIAJIJGH_01285 334390.LAF_1108 7.4e-214 749.6 Lactobacillaceae aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0976,iNJ661.Rv2540c Bacteria 1TQ40@1239,3F502@33958,4HA0H@91061,COG0082@1,COG0082@2 NA|NA|NA E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system KIAJIJGH_01286 334390.LAF_1107 5e-104 383.6 Lactobacillaceae Bacteria 1VC0E@1239,2E0PE@1,32W87@2,3F60R@33958,4HKI6@91061 NA|NA|NA KIAJIJGH_01287 334390.LAF_1106 2.9e-235 820.8 Lactobacillaceae aroA GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 1.3.1.12,1.3.1.43,2.5.1.19 ko:K00210,ko:K00220,ko:K00800 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00022,M00025,M00040 R00732,R01728,R03460 RC00125,RC00350 ko00000,ko00001,ko00002,ko01000 iLJ478.TM0345 Bacteria 1TPIH@1239,3F5B2@33958,4HBHZ@91061,COG0128@1,COG0128@2 NA|NA|NA E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate KIAJIJGH_01288 334390.LAF_1105 6.9e-198 696.4 Lactobacillaceae tyrA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 ko:K00210,ko:K00220,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025,M00040 R00732,R01728 RC00125 ko00000,ko00001,ko00002,ko01000 iYO844.BSU22610 Bacteria 1TPXG@1239,3F589@33958,4HBI4@91061,COG0287@1,COG0287@2 NA|NA|NA E prephenate dehydrogenase KIAJIJGH_01289 334390.LAF_1104 5.6e-89 333.6 Lactobacillaceae aroK GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019438,GO:0019632,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615 1.1.1.25,2.7.1.71,4.2.1.10,4.2.3.4 ko:K00014,ko:K00891,ko:K03785,ko:K03786,ko:K13829,ko:K15546 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R02413,R03083,R03084 RC00002,RC00078,RC00206,RC00847,RC00848 ko00000,ko00001,ko00002,ko01000,ko03000 iAPECO1_1312.APECO1_1620,iECOK1_1307.ECOK1_0367,iECS88_1305.ECS88_0383,iUMN146_1321.UM146_15425,iUTI89_1310.UTI89_C0407,iYL1228.KPN_00332 Bacteria 1VA6Z@1239,3F7FE@33958,4HKD6@91061,COG0703@1,COG0703@2 NA|NA|NA F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate KIAJIJGH_01290 334390.LAF_1103 1.6e-216 758.4 Lactobacillaceae aspB ko:K10907 ko00000,ko01000,ko01007 Bacteria 1TP0J@1239,3F4FA@33958,4HF8A@91061,COG0436@1,COG0436@2 NA|NA|NA E DegT/DnrJ/EryC1/StrS aminotransferase family KIAJIJGH_01291 334390.LAF_1102 2.5e-183 647.9 Lactobacillaceae 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 R00704 RC00044 ko00000,ko00001,ko01000 Bacteria 1TSZ6@1239,3F4US@33958,4HCIS@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family KIAJIJGH_01292 334390.LAF_1101 5.5e-178 630.2 Lactobacillaceae hepT 2.5.1.30,2.5.1.90 ko:K00805,ko:K02523 ko00900,ko01110,map00900,map01110 R09247,R09248 RC00279 ko00000,ko00001,ko01000,ko01006 Bacteria 1TR0U@1239,3F4GC@33958,4H9RH@91061,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family KIAJIJGH_01293 334390.LAF_1100 5.4e-156 557.0 Lactobacillaceae menA 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1TSZV@1239,3F3JM@33958,4HA68@91061,COG1575@1,COG1575@2 NA|NA|NA H 1,4-dihydroxy-2-naphthoate KIAJIJGH_01294 334390.LAF_1099 6.7e-23 112.5 Lactobacillaceae Bacteria 1U75W@1239,29PXD@1,30AVR@2,3F90N@33958,4IH0H@91061 NA|NA|NA S Virus attachment protein p12 family KIAJIJGH_01295 334390.LAF_1098 0.0 1273.5 Lactobacillaceae feoB ko:K04759 ko00000,ko02000 9.A.8.1 iSB619.SA_RS13395 Bacteria 1TP7E@1239,3F553@33958,4HBCS@91061,COG0370@1,COG0370@2 NA|NA|NA P transporter of a GTP-driven Fe(2 ) uptake system KIAJIJGH_01296 334390.LAF_1097 3.9e-33 146.7 Lactobacillaceae feoA ko:K04758 ko00000,ko02000 Bacteria 1U69I@1239,3F7DB@33958,4IG0P@91061,COG1918@1,COG1918@2 NA|NA|NA P FeoA domain KIAJIJGH_01297 334390.LAF_1096 8.5e-145 519.6 Lactobacillaceae sufC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 ko:K09013 ko00000,ko02000 iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710 Bacteria 1TQ98@1239,3F3XT@33958,4HAD9@91061,COG0396@1,COG0396@2 NA|NA|NA O FeS assembly ATPase SufC KIAJIJGH_01298 334390.LAF_1095 5.8e-244 849.7 Lactobacillaceae sufD ko:K07033,ko:K09015 ko00000 Bacteria 1TRT0@1239,3F4BR@33958,4HB6W@91061,COG0719@1,COG0719@2 NA|NA|NA O FeS assembly protein SufD KIAJIJGH_01299 334390.LAF_1094 4e-234 817.0 Lactobacillaceae sufS 2.8.1.7,4.4.1.16 ko:K04487,ko:K11717 ko00450,ko00730,ko01100,ko04122,map00450,map00730,map01100,map04122 R03599,R07460,R11528,R11529 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1TQ1W@1239,3F3UP@33958,4HA6Z@91061,COG0520@1,COG0520@2 NA|NA|NA E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine KIAJIJGH_01300 334390.LAF_1093 3.2e-83 314.3 Lactobacillaceae nifU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 ko:K04488 ko00000 Bacteria 1V3H9@1239,3F6WP@33958,4HIJ0@91061,COG0822@1,COG0822@2 NA|NA|NA C SUF system FeS assembly protein, NifU family KIAJIJGH_01301 334390.LAF_1092 4.2e-272 943.3 Lactobacillaceae sufB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 ko:K07033,ko:K09014 ko00000 Bacteria 1TQ21@1239,3F44I@33958,4HA1Z@91061,COG0719@1,COG0719@2 NA|NA|NA O assembly protein SufB KIAJIJGH_01302 334390.LAF_1091 3.5e-178 630.9 Lactobacillaceae fecB ko:K02016 ko02010,map02010 M00240 ko00000,ko00001,ko00002,ko02000 3.A.1.14 Bacteria 1V1B8@1239,3F3R5@33958,4I2JG@91061,COG0614@1,COG0614@2 NA|NA|NA P Periplasmic binding protein KIAJIJGH_01306 334390.LAF_1234 2.6e-245 854.4 Lactobacillaceae ffh GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 Bacteria 1TP06@1239,3F40R@33958,4H9T4@91061,COG0541@1,COG0541@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY KIAJIJGH_01307 334390.LAF_1235 3.7e-57 227.3 Lactobacillaceae ylxM GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772 ko:K09787 ko00000 Bacteria 1VEGP@1239,3F7FG@33958,4HKK6@91061,COG2739@1,COG2739@2 NA|NA|NA S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein KIAJIJGH_01308 334390.LAF_1236 2.5e-144 518.1 Lactobacillaceae ftsY ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 Bacteria 1TPRI@1239,3F3YC@33958,4HA6A@91061,COG0552@1,COG0552@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) KIAJIJGH_01309 334390.LAF_1237 3.9e-37 160.2 Lactobacillaceae smc ko:K03529 ko00000,ko03036 Bacteria 1TPJV@1239,3F478@33958,4HB89@91061,COG1196@1,COG1196@2 NA|NA|NA D Required for chromosome condensation and partitioning KIAJIJGH_01310 334390.LAF_1236 1.3e-14 85.9 Lactobacillaceae ftsY ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 Bacteria 1TPRI@1239,3F3YC@33958,4HA6A@91061,COG0552@1,COG0552@2 NA|NA|NA U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) KIAJIJGH_01311 334390.LAF_1237 0.0 1460.7 Lactobacillaceae smc ko:K03529 ko00000,ko03036 Bacteria 1TPJV@1239,3F478@33958,4HB89@91061,COG1196@1,COG1196@2 NA|NA|NA D Required for chromosome condensation and partitioning KIAJIJGH_01312 334390.LAF_1238 5.2e-130 470.3 Lactobacillaceae rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Bacteria 1TPGC@1239,3F564@33958,4HAWU@91061,COG0571@1,COG0571@2 NA|NA|NA J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism KIAJIJGH_01313 334390.LAF_1239 4.5e-36 156.8 Lactobacillaceae acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 ko:K02078 ko00000,ko00001 Bacteria 1VEE3@1239,3F7F4@33958,4HNQ0@91061,COG0236@1,COG0236@2 NA|NA|NA IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis KIAJIJGH_01314 334390.LAF_1240 2.8e-164 584.7 Lactobacillaceae plsX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPXS@1239,3F4N9@33958,4HA0R@91061,COG0416@1,COG0416@2 NA|NA|NA I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA KIAJIJGH_01315 334390.LAF_1241 0.0 1219.1 Lactobacillaceae recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TQ6I@1239,3F3JW@33958,4HAWN@91061,COG1200@1,COG1200@2 NA|NA|NA L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) KIAJIJGH_01316 334390.LAF_1242 2.9e-304 1050.4 Lactobacillaceae yloV ko:K07030 ko00000 Bacteria 1TQMX@1239,3F3X0@33958,4HBSE@91061,COG1461@1,COG1461@2 NA|NA|NA S DAK2 domain fusion protein YloV KIAJIJGH_01317 334390.LAF_1243 3.6e-58 230.7 Lactobacillaceae asp Bacteria 1V731@1239,3F72W@33958,4HIS4@91061,COG1302@1,COG1302@2 NA|NA|NA S Asp23 family, cell envelope-related function KIAJIJGH_01318 334390.LAF_1244 7.2e-26 122.5 Lactobacillaceae rpmB GO:0003674,GO:0003735,GO:0005198 ko:K02902 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1TVQH@1239,3FCDR@33958,4HSV0@91061,COG0227@1,COG0227@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL28 family KIAJIJGH_01319 334390.LAF_1245 3.4e-123 447.6 Lactobacillaceae thiN 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 R00619 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1VA0W@1239,3F4N8@33958,4HHS1@91061,COG1564@1,COG1564@2 NA|NA|NA H thiamine pyrophosphokinase KIAJIJGH_01320 334390.LAF_1246 1.1e-118 432.6 Lactobacillaceae rpe 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQK8@1239,3F4KX@33958,4H9RW@91061,COG0036@1,COG0036@2 NA|NA|NA G Belongs to the ribulose-phosphate 3-epimerase family KIAJIJGH_01321 334390.LAF_1247 1.6e-163 582.0 Lactobacillaceae rsgA 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 Bacteria 1TPSQ@1239,3F3XH@33958,4HA9W@91061,COG1162@1,COG1162@2 NA|NA|NA S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit KIAJIJGH_01322 334390.LAF_1248 0.0 1189.1 Lactobacillaceae Bacteria 1TP3F@1239,3F4G6@33958,4H9KD@91061,COG0515@1,COG0515@2 NA|NA|NA KLT serine threonine protein kinase KIAJIJGH_01323 334390.LAF_1249 2.2e-131 474.9 Lactobacillaceae stp 3.1.3.16 ko:K20074 ko00000,ko01000,ko01009 Bacteria 1V6K5@1239,3F4UI@33958,4HCDR@91061,COG0631@1,COG0631@2 NA|NA|NA T phosphatase KIAJIJGH_01324 334390.LAF_1250 4.5e-247 860.1 Lactobacillaceae sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 ko00000,ko01000,ko03009 Bacteria 1TP3N@1239,3F45F@33958,4HBQ6@91061,COG0144@1,COG0144@2,COG0781@1,COG0781@2 NA|NA|NA J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA KIAJIJGH_01325 334390.LAF_1251 3e-173 614.4 Lactobacillaceae fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 R03940 RC00026,RC00165 ko00000,ko00001,ko01000 iSB619.SA_RS06010 Bacteria 1TQ32@1239,3F4N7@33958,4HART@91061,COG0223@1,COG0223@2 NA|NA|NA J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus KIAJIJGH_01326 334390.LAF_1252 0.0 1595.5 Lactobacillaceae priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Bacteria 1TNYB@1239,3F3N8@33958,4H9WW@91061,COG1198@1,COG1198@2 NA|NA|NA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA KIAJIJGH_01327 334390.LAF_1253 5.4e-215 753.4 Lactobacillaceae coaBC 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPP3@1239,3F3XX@33958,4HAK8@91061,COG0452@1,COG0452@2 NA|NA|NA H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine KIAJIJGH_01328 334390.LAF_1254 3.2e-46 190.7 Lactobacillaceae rpoZ GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Bacteria 1VK74@1239,3F81N@33958,4HNHS@91061,COG1758@1,COG1758@2 NA|NA|NA K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits KIAJIJGH_01329 334390.LAF_1255 3.9e-113 414.1 Lactobacillaceae gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15680 Bacteria 1TP0M@1239,3F3X9@33958,4HAYW@91061,COG0194@1,COG0194@2 NA|NA|NA F Essential for recycling GMP and indirectly, cGMP KIAJIJGH_01330 575594.ACOH01000003_gene758 2.5e-15 88.2 Lactobacillaceae Bacteria 1U6WT@1239,29PTH@1,30ANM@2,3F8MX@33958,4IGQZ@91061 NA|NA|NA KIAJIJGH_01331 1235801.C822_00667 3.3e-36 157.9 Lactobacillaceae ko:K07483 ko00000 Bacteria 1V1QC@1239,3F5BG@33958,4HH7E@91061,COG2963@1,COG2963@2 NA|NA|NA L Helix-turn-helix domain KIAJIJGH_01332 1235801.C822_00666 1.7e-98 365.5 Lactobacillaceae Bacteria 1TQEG@1239,3F43M@33958,4HD6M@91061,COG2801@1,COG2801@2 NA|NA|NA L hmm pf00665 KIAJIJGH_01333 334390.LAF_1257 2.8e-307 1060.4 Lactobacillaceae recN GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360 ko:K03631,ko:K13582 ko04112,map04112 ko00000,ko00001,ko03400 Bacteria 1TP99@1239,3F43U@33958,4H9ZR@91061,COG0497@1,COG0497@2 NA|NA|NA L May be involved in recombinational repair of damaged DNA KIAJIJGH_01334 334390.LAF_1258 6.2e-76 290.0 Lactobacillaceae argR GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 ko:K03402 ko00000,ko03000 Bacteria 1V1R7@1239,3F71C@33958,4HFY8@91061,COG1438@1,COG1438@2 NA|NA|NA K Regulates arginine biosynthesis genes KIAJIJGH_01335 334390.LAF_1259 6.4e-148 530.0 Lactobacillaceae rrmJ 2.1.1.226,2.1.1.227 ko:K06442 ko00000,ko01000,ko03009 Bacteria 1TPE4@1239,3F45T@33958,4HAPY@91061,COG1189@1,COG1189@2 NA|NA|NA J Ribosomal RNA large subunit methyltransferase J KIAJIJGH_01336 334390.LAF_1260 6.2e-157 560.1 Lactobacillaceae ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 ko:K00795,ko:K02523,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061,R09248 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1TPQY@1239,3F436@33958,4HA8E@91061,COG0142@1,COG0142@2 NA|NA|NA H Belongs to the FPP GGPP synthase family KIAJIJGH_01337 1203076.CAKF01000012_gene1146 1e-18 99.4 Firmicutes xseB 3.1.11.6 ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1VK9I@1239,COG1722@1,COG1722@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides KIAJIJGH_01338 334390.LAF_1262 2.3e-257 894.4 Lactobacillaceae xseA 3.1.11.6 ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TP4E@1239,3F4RE@33958,4HAN2@91061,COG1570@1,COG1570@2 NA|NA|NA L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides KIAJIJGH_01339 334390.LAF_1263 2.6e-160 571.2 Lactobacillaceae folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP1P@1239,3F46A@33958,4H9Q6@91061,COG0190@1,COG0190@2 NA|NA|NA F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate KIAJIJGH_01340 334390.LAF_1264 2e-68 265.0 Lactobacillaceae nusB ko:K03625 ko00000,ko03009,ko03021 Bacteria 1VA9B@1239,3F7KW@33958,4HKMU@91061,COG0781@1,COG0781@2 NA|NA|NA K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons KIAJIJGH_01341 334390.LAF_1265 4.1e-72 277.3 Lactobacillaceae yqhY ko:K10947 ko00000,ko03000 Bacteria 1V4IC@1239,3F71X@33958,4HJ7T@91061,COG1302@1,COG1302@2 NA|NA|NA S Asp23 family, cell envelope-related function KIAJIJGH_01342 334390.LAF_1266 3.1e-206 724.2 Lactobacillaceae pepP 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 ko00000,ko01000,ko01002 Bacteria 1TQ44@1239,3F4DR@33958,4HAT7@91061,COG0006@1,COG0006@2 NA|NA|NA E Creatinase/Prolidase N-terminal domain KIAJIJGH_01343 334390.LAF_1267 7.1e-46 189.5 Lactobacillaceae rpmA GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 ko:K02899 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6HW@1239,3F6WU@33958,4HIMN@91061,COG0211@1,COG0211@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL27 family KIAJIJGH_01344 334390.LAF_1268 9e-53 212.6 Lactobacillaceae ysxB ko:K07584 ko00000 Bacteria 1VEQ9@1239,3F839@33958,4HNMV@91061,COG2868@1,COG2868@2 NA|NA|NA J Cysteine protease Prp KIAJIJGH_01345 334390.LAF_1269 5.2e-50 203.4 Lactobacillaceae rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02888 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V9YH@1239,3F6WT@33958,4HIGK@91061,COG0261@1,COG0261@2 NA|NA|NA J This protein binds to 23S rRNA in the presence of protein L20 KIAJIJGH_01346 334390.LAF_1270 9.6e-115 419.5 Lactobacillaceae Bacteria 1VGVA@1239,3F3TB@33958,4HPAG@91061,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator KIAJIJGH_01348 334390.LAF_1271 6.6e-93 346.7 Lactobacillaceae dut Bacteria 1VGAY@1239,3F6E4@33958,4HPDT@91061,COG4508@1,COG4508@2 NA|NA|NA S Protein conserved in bacteria KIAJIJGH_01349 334390.LAF_1272 2.3e-176 624.8 Lactobacillaceae Bacteria 1VK1W@1239,2F367@1,33W0S@2,3F3MT@33958,4HWH4@91061 NA|NA|NA KIAJIJGH_01350 334390.LAF_1273 2.4e-148 531.6 Lactobacillaceae Bacteria 1V8SY@1239,2AZ1J@1,31R7P@2,3F4MX@33958,4HJRD@91061 NA|NA|NA KIAJIJGH_01351 334390.LAF_1274 4.7e-13 79.3 Lactobacillaceae Bacteria 1U751@1239,29PWQ@1,30AV2@2,3F8ZI@33958,4IGZQ@91061 NA|NA|NA KIAJIJGH_01352 334390.LAF_1275 3.8e-262 910.2 Lactobacillaceae glnA 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 Bacteria 1TNZA@1239,3F41A@33958,4HACE@91061,COG0174@1,COG0174@2 NA|NA|NA E glutamine synthetase KIAJIJGH_01353 334390.LAF_1276 1.2e-171 609.0 Lactobacillaceae miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 Bacteria 1TPSC@1239,3F3XS@33958,4HAVW@91061,COG0324@1,COG0324@2 NA|NA|NA F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) KIAJIJGH_01354 334390.LAF_1277 1.4e-23 114.8 Lactobacillaceae WQ51_02665 Bacteria 1VPEZ@1239,2C91M@1,33E1E@2,3F8C0@33958,4HRR2@91061 NA|NA|NA S Protein of unknown function (DUF3042) KIAJIJGH_01355 334390.LAF_1278 1.5e-71 275.4 Lactobacillaceae yqhL Bacteria 1VAI7@1239,3F67E@33958,4HKCE@91061,COG0607@1,COG0607@2 NA|NA|NA P Rhodanese-like protein KIAJIJGH_01356 334390.LAF_1279 2.9e-179 634.4 Lactobacillaceae glk GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS07790 Bacteria 1TPKW@1239,3F4F0@33958,4HBAU@91061,COG1940@1,COG1940@2 NA|NA|NA G Glucokinase KIAJIJGH_01357 334390.LAF_1280 9.6e-36 155.6 Lactobacillaceae yqgQ Bacteria 1VK83@1239,3F83I@33958,4HRG2@91061,COG4483@1,COG4483@2 NA|NA|NA S Bacterial protein of unknown function (DUF910) KIAJIJGH_01358 334390.LAF_1281 3.5e-106 391.0 Lactobacillaceae gluP 3.4.21.105 ko:K19225 ko00000,ko01000,ko01002 Bacteria 1TQXT@1239,3F3WR@33958,4HCDF@91061,COG0705@1,COG0705@2 NA|NA|NA S Peptidase, S54 family KIAJIJGH_01359 334390.LAF_1282 9.2e-98 362.8 Lactobacillaceae ygfA GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 R02301 RC00183 ko00000,ko00001,ko01000 iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298 Bacteria 1VA91@1239,3F4KQ@33958,4HM35@91061,COG0212@1,COG0212@2 NA|NA|NA H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family KIAJIJGH_01360 334390.LAF_1283 3.2e-21 106.7 Lactobacillaceae rpmG ko:K02913 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEJ4@1239,3F828@33958,4HNIM@91061,COG0267@1,COG0267@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL33 family KIAJIJGH_01361 334390.LAF_1284 0.0 1312.0 Lactobacillaceae pbp2b 3.4.16.4 ko:K00687,ko:K05515,ko:K12553,ko:K21465 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Bacteria 1TQHY@1239,3F3KH@33958,4HAFX@91061,COG0768@1,COG0768@2 NA|NA|NA M Penicillin-binding Protein KIAJIJGH_01362 334390.LAF_1285 0.0 1719.1 Lactobacillaceae Bacteria 1TRR1@1239,3F49G@33958,4HBW6@91061,COG4485@1,COG4485@2 NA|NA|NA S membrane KIAJIJGH_01363 334390.LAF_1286 2.2e-79 301.6 Lactobacillaceae greA GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 ko:K03624 ko00000,ko03021 Bacteria 1V44S@1239,3F4ZF@33958,4HGZU@91061,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides KIAJIJGH_01364 334390.LAF_1287 3e-116 424.5 Lactobacillaceae udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 iSBO_1134.SBO_0893 Bacteria 1TQ4V@1239,3F3KE@33958,4HAVR@91061,COG0572@1,COG0572@2 NA|NA|NA F Cytidine monophosphokinase KIAJIJGH_01365 334390.LAF_1288 0.0 1595.9 Lactobacillaceae pheT GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iG2583_1286.G2583_2160,iPC815.YPO2428 Bacteria 1TP98@1239,3F3V3@33958,4HAQ9@91061,COG0072@1,COG0072@2 NA|NA|NA J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily KIAJIJGH_01366 334390.LAF_1289 1.9e-197 694.9 Lactobacillaceae pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPFW@1239,3F4NT@33958,4HAVN@91061,COG0016@1,COG0016@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily KIAJIJGH_01367 334390.LAF_1290 7.8e-60 236.1 Lactobacillaceae yodB Bacteria 1VBI7@1239,3F7FK@33958,4HKBR@91061,COG1733@1,COG1733@2 NA|NA|NA K Transcriptional regulator, HxlR family KIAJIJGH_01368 334390.LAF_1291 7.6e-91 339.7 Lactobacillaceae XK27_09705 6.1.1.14 ko:K01879,ko:K06950 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1V4QX@1239,3F64N@33958,4HHW0@91061,COG1418@1,COG1418@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. KIAJIJGH_01369 334390.LAF_1292 4e-142 510.8 Lactobacillaceae spoU 2.1.1.185 ko:K03218,ko:K03437 ko00000,ko01000,ko03009,ko03016 Bacteria 1V3JP@1239,3F3NF@33958,4HCF5@91061,COG0566@1,COG0566@2 NA|NA|NA J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family KIAJIJGH_01370 334390.LAF_1293 4.1e-46 190.3 Lactobacillaceae acyP GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 iSB619.SA_RS07020,iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036 Bacteria 1VEM9@1239,3F81R@33958,4HNN7@91061,COG1254@1,COG1254@2 NA|NA|NA C Belongs to the acylphosphatase family KIAJIJGH_01371 334390.LAF_1294 1e-141 509.6 Lactobacillaceae yidC ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 1TSDN@1239,3F3P3@33958,4HCC8@91061,COG0706@1,COG0706@2 NA|NA|NA U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins KIAJIJGH_01372 334390.LAF_1295 5.1e-69 266.9 Lactobacillaceae def_1 3.5.1.31,3.5.1.88 ko:K01450,ko:K01462 ko00270,ko00630,map00270,map00630 R00653 RC00165,RC00323 ko00000,ko00001,ko01000 Bacteria 1V73T@1239,3F6ZA@33958,4HISW@91061,COG0242@1,COG0242@2 NA|NA|NA J Removes the formyl group from the N-terminal Met of newly synthesized proteins KIAJIJGH_01373 334390.LAF_1296 1.6e-233 815.1 Lactobacillaceae Bacteria 1TP6V@1239,3FBD2@33958,4IPM0@91061,COG0534@1,COG0534@2 NA|NA|NA V MatE KIAJIJGH_01374 334390.LAF_1297 5.8e-280 969.5 Lactobacillaceae arlS GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K18940 ko02020,map02020 M00716,M00717 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TPSK@1239,3F3NU@33958,4HAH5@91061,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase KIAJIJGH_01375 334390.LAF_1298 5.6e-121 440.3 Lactobacillaceae Bacteria 1TS81@1239,3F421@33958,4H9NE@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator KIAJIJGH_01376 334390.LAF_1299 7.2e-28 129.0 Lactobacillaceae rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 ko:K02911 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1VEFI@1239,3FCDY@33958,4HNIZ@91061,COG0333@1,COG0333@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL32 family KIAJIJGH_01377 334390.LAF_1300 1.2e-97 362.5 Lactobacillaceae yceD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 ko:K07040 ko00000 Bacteria 1VB08@1239,3F61Z@33958,4HME9@91061,COG1399@1,COG1399@2 NA|NA|NA S Uncharacterized ACR, COG1399 KIAJIJGH_01378 334390.LAF_1301 4.5e-216 756.9 Lactobacillaceae ylbM Bacteria 1TPP2@1239,3F3QC@33958,4HAZJ@91061,COG1323@1,COG1323@2 NA|NA|NA S Belongs to the UPF0348 family KIAJIJGH_01379 334390.LAF_1302 1.2e-140 505.8 Lactobacillaceae yqeM Bacteria 1TQUF@1239,3F4KM@33958,4HD2W@91061,COG0500@1,COG2226@2 NA|NA|NA Q Methyltransferase KIAJIJGH_01380 334390.LAF_1303 2.7e-58 231.1 Lactobacillaceae rsfS GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 ko:K09710 ko00000,ko03009 Bacteria 1VA2Z@1239,3F7QN@33958,4HKEJ@91061,COG0799@1,COG0799@2 NA|NA|NA J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation KIAJIJGH_01381 334390.LAF_1304 7.3e-112 409.8 Lactobacillaceae nadD 2.7.6.3,2.7.7.18 ko:K00950,ko:K00969,ko:K06950 ko00760,ko00790,ko01100,map00760,map00790,map01100 M00115,M00126,M00841 R00137,R03005,R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V6Y1@1239,3F47C@33958,4HHRY@91061,COG1713@1,COG1713@2 NA|NA|NA H Hydrolase, HD family KIAJIJGH_01382 334390.LAF_1305 2.1e-93 348.6 Lactobacillaceae nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 ko:K00969,ko:K03574 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 Bacteria 1V3SK@1239,3F4D6@33958,4HGXK@91061,COG1057@1,COG1057@2 NA|NA|NA H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) KIAJIJGH_01383 334390.LAF_1306 2.6e-49 201.1 Lactobacillaceae yhbY GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275 ko:K07574 ko00000,ko03009 Bacteria 1VEGM@1239,3F7EW@33958,4HKC7@91061,COG1534@1,COG1534@2 NA|NA|NA J RNA-binding protein KIAJIJGH_01384 334390.LAF_1307 7.6e-216 756.1 Lactobacillaceae yqeH GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113 ko:K06948 ko00000,ko03009 Bacteria 1TPM2@1239,3F4JU@33958,4HAAF@91061,COG1161@1,COG1161@2 NA|NA|NA S Ribosome biogenesis GTPase YqeH KIAJIJGH_01385 334390.LAF_1308 2.2e-96 358.2 Lactobacillaceae yqeG ko:K07015 ko00000 Bacteria 1V6KM@1239,3F46V@33958,4HGAV@91061,COG2179@1,COG2179@2 NA|NA|NA S HAD phosphatase, family IIIA KIAJIJGH_01386 1423758.BN55_07970 5e-24 117.5 Lactobacillaceae yoaK Bacteria 1V1VQ@1239,3F5F5@33958,4HM4F@91061,COG3619@1,COG3619@2 NA|NA|NA S Protein of unknown function (DUF1275) KIAJIJGH_01387 387344.LVIS_1429 1.7e-12 78.2 Lactobacillaceae yoaK Bacteria 1V1VQ@1239,3F5F5@33958,4HM4F@91061,COG3619@1,COG3619@2 NA|NA|NA S Protein of unknown function (DUF1275) KIAJIJGH_01388 334390.LAF_1309 6.6e-57 226.5 Lactobacillaceae rplT GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 ko:K02887 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6DB@1239,3F6HZ@33958,4HH2W@91061,COG0292@1,COG0292@2 NA|NA|NA J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit KIAJIJGH_01389 334390.LAF_1310 1.5e-26 124.8 Lactobacillaceae rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 ko:K02916 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VF5W@1239,3F7CQ@33958,4HNIQ@91061,COG0291@1,COG0291@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL35 family KIAJIJGH_01390 334390.LAF_1311 1.7e-85 322.0 Lactobacillaceae infC GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 ko:K02520 ko00000,ko03012,ko03029 Bacteria 1V1RC@1239,3F4MS@33958,4HFUS@91061,COG0290@1,COG0290@2 NA|NA|NA J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins KIAJIJGH_01391 334390.LAF_1312 7.4e-172 609.8 Lactobacillaceae dnaI GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 ko:K11144 ko00000,ko03032 Bacteria 1TPZX@1239,3F4JK@33958,4HABS@91061,COG1484@1,COG1484@2 NA|NA|NA L Primosomal protein DnaI KIAJIJGH_01392 334390.LAF_1313 3e-251 874.0 Lactobacillaceae dnaB ko:K03346 ko00000,ko03032 Bacteria 1TSBB@1239,3F5D7@33958,4H9RI@91061,COG3611@1,COG3611@2 NA|NA|NA L replication initiation and membrane attachment KIAJIJGH_01393 334390.LAF_1314 8.5e-81 306.2 Lactobacillaceae nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K07738 ko00000,ko03000 Bacteria 1V3JA@1239,3F65S@33958,4HGXA@91061,COG1327@1,COG1327@2 NA|NA|NA K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes KIAJIJGH_01394 334390.LAF_1315 3.5e-106 391.0 Lactobacillaceae coaE 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 Bacteria 1V6FS@1239,3F6WF@33958,4HII3@91061,COG0237@1,COG0237@2 NA|NA|NA F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A KIAJIJGH_01395 334390.LAF_1316 2.1e-162 578.2 Lactobacillaceae fpg 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPM9@1239,3F43E@33958,4H9Q7@91061,COG0266@1,COG0266@2 NA|NA|NA L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates KIAJIJGH_01396 334390.LAF_1317 0.0 1726.8 Lactobacillaceae polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 Bacteria 1TPKJ@1239,3F3ZA@33958,4H9S7@91061,COG0258@1,COG0258@2,COG0749@1,COG0749@2 NA|NA|NA L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity KIAJIJGH_01397 334390.LAF_1318 1.5e-138 498.8 Lactobacillaceae aroD ko:K06889 ko00000 Bacteria 1UXYN@1239,3FB9J@33958,4HA7V@91061,COG1073@1,COG1073@2 NA|NA|NA S Serine hydrolase (FSH1) KIAJIJGH_01398 334390.LAF_1319 1.8e-114 418.7 Lactobacillaceae ybhL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K06890 ko00000 Bacteria 1V66F@1239,3FBMP@33958,4IR6X@91061,COG0670@1,COG0670@2 NA|NA|NA S Belongs to the BI1 family KIAJIJGH_01399 334390.LAF_1320 1.4e-250 871.7 Lactobacillaceae mpl GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0042802,GO:0044424,GO:0044464 6.3.2.4,6.3.2.45,6.3.2.8 ko:K01921,ko:K01924,ko:K02558 ko00471,ko00473,ko00550,ko01100,ko01502,map00471,map00473,map00550,map01100,map01502 R01150,R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 iSDY_1059.SDY_4251 Bacteria 1TQ5H@1239,3F49J@33958,4HAR4@91061,COG0773@1,COG0773@2 NA|NA|NA M Belongs to the MurCDEF family KIAJIJGH_01400 334390.LAF_1321 2e-117 428.3 Lactobacillaceae pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890,ko:K06878 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1V3R1@1239,3F58U@33958,4HHBI@91061,COG0073@1,COG0073@2 NA|NA|NA J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily KIAJIJGH_01401 334390.LAF_1322 6.5e-56 223.0 Lactobacillaceae ytpP GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 2.7.1.180,5.3.4.1 ko:K01829,ko:K03671,ko:K03734,ko:K06196 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko02000,ko03110 5.A.1.2 Bacteria 1VAS6@1239,3F72K@33958,4HKGM@91061,COG0526@1,COG0526@2 NA|NA|NA CO Thioredoxin KIAJIJGH_01402 334390.LAF_1323 5.1e-59 233.4 Lactobacillaceae ytzB Bacteria 1VMU8@1239,3F73X@33958,4HREZ@91061,COG5584@1,COG5584@2 NA|NA|NA S Small secreted protein KIAJIJGH_01403 334390.LAF_1324 5.1e-124 450.3 Lactobacillaceae trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.297,2.1.1.33 ko:K02493,ko:K03439 R10806 RC00003,RC03279 ko00000,ko01000,ko03012,ko03016 Bacteria 1TQCA@1239,3F3QM@33958,4HC08@91061,COG0220@1,COG0220@2 NA|NA|NA J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA KIAJIJGH_01404 334390.LAF_1325 7.7e-211 739.6 Lactobacillaceae ecsB ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V1VG@1239,3F4HH@33958,4HG1K@91061,COG4473@1,COG4473@2 NA|NA|NA U ABC transporter KIAJIJGH_01405 334390.LAF_1326 2.3e-133 481.5 Lactobacillaceae ecsA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQIH@1239,3F444@33958,4HA2B@91061,COG1131@1,COG1131@2 NA|NA|NA V ABC transporter, ATP-binding protein KIAJIJGH_01406 334390.LAF_1327 1.4e-77 295.4 Lactobacillaceae hit ko:K02503 ko00000,ko04147 Bacteria 1V9ZJ@1239,3F6K5@33958,4HIG2@91061,COG0537@1,COG0537@2 NA|NA|NA FG histidine triad KIAJIJGH_01408 334390.LAF_1329 7e-149 533.5 Lactobacillaceae prsA 5.2.1.8 ko:K02597,ko:K07533 ko00000,ko01000,ko03110 Bacteria 1V5RY@1239,3FBHM@33958,4HH41@91061,COG0760@1,COG0760@2 NA|NA|NA M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins KIAJIJGH_01409 334390.LAF_1330 5.7e-180 636.7 Lactobacillaceae yhaM GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 ko:K03698 ko00000,ko01000,ko03019 Bacteria 1TPIU@1239,3F4SF@33958,4HB1M@91061,COG3481@1,COG3481@2 NA|NA|NA S Metal dependent phosphohydrolases with conserved 'HD' motif. KIAJIJGH_01410 334390.LAF_1331 9.8e-56 222.6 Lactobacillaceae yheA Bacteria 1VASS@1239,3F822@33958,4HKKC@91061,COG3679@1,COG3679@2 NA|NA|NA S Belongs to the UPF0342 family KIAJIJGH_01411 334390.LAF_1332 0.0 1313.5 Lactobacillaceae pbp2A 2.4.1.129,3.4.16.4 ko:K05365,ko:K05366,ko:K12555,ko:K21464 ko00550,ko01100,ko01501,map00550,map01100,map01501 R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 GT51 Bacteria 1TPM5@1239,3F49Q@33958,4H9SA@91061,COG0744@1,COG0744@2 NA|NA|NA M penicillin-binding protein KIAJIJGH_01412 334390.LAF_1333 0.0 1109.7 Lactobacillaceae argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Bacteria 1TPEZ@1239,3F4DE@33958,4HAR3@91061,COG0018@1,COG0018@2 NA|NA|NA J Arginyl-tRNA synthetase KIAJIJGH_01413 334390.LAF_1335 5.5e-35 153.7 Lactobacillaceae Bacteria 1U6CF@1239,2DKPT@1,30A91@2,3F7KP@33958,4IG44@91061 NA|NA|NA KIAJIJGH_01415 334390.LAF_1336 7e-201 706.4 Lactobacillaceae folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796,ko:K18824,ko:K18974 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1TPKT@1239,3F4SS@33958,4H9SY@91061,COG0294@1,COG0294@2 NA|NA|NA H dihydropteroate synthase KIAJIJGH_01416 334390.LAF_1337 1.2e-106 392.5 Lactobacillaceae xtp 2.5.1.15,3.6.1.66 ko:K00796,ko:K02428 ko00230,ko00790,ko01100,map00230,map00790,map01100 M00126,M00841 R00426,R00720,R01855,R02100,R02720,R03066,R03067,R03531 RC00002,RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 Bacteria 1VWAB@1239,3F4R5@33958,4HWPY@91061,COG0127@1,COG0127@2 NA|NA|NA F Ham1 family KIAJIJGH_01417 334390.LAF_1338 2.2e-243 847.8 Lactobacillaceae folC 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPX5@1239,3F3ZR@33958,4HBJM@91061,COG0285@1,COG0285@2 NA|NA|NA H Belongs to the folylpolyglutamate synthase family KIAJIJGH_01418 334390.LAF_1339 1.5e-103 382.1 Lactobacillaceae folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R03503,R04639,R05046,R05048 RC00002,RC00017,RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv3609c Bacteria 1TRNM@1239,3F4A0@33958,4HAXS@91061,COG0302@1,COG0302@2 NA|NA|NA F GTP cyclohydrolase 1 KIAJIJGH_01419 334390.LAF_1340 1.3e-93 349.0 Lactobacillaceae folK 1.13.11.81,2.5.1.15,2.7.6.3,3.5.4.16,4.1.2.25,5.1.99.8 ko:K00796,ko:K00950,ko:K01495,ko:K01633,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841,M00842,M00843 R00428,R03066,R03067,R03503,R03504,R04639,R05046,R05048,R11037,R11073 RC00002,RC00017,RC00121,RC00263,RC00294,RC00323,RC00721,RC00842,RC00943,RC00945,RC01188,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 Bacteria 1V6PR@1239,3F6SY@33958,4HIMG@91061,COG0801@1,COG0801@2 NA|NA|NA H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) KIAJIJGH_01420 334390.LAF_1341 8.4e-63 246.1 Lactobacillaceae folB 1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8 ko:K00796,ko:K00950,ko:K01633,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841 R03066,R03067,R03503,R03504,R11037,R11073 RC00002,RC00017,RC00121,RC00721,RC00842,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 Bacteria 1VA0I@1239,3F7N6@33958,4HKKK@91061,COG1539@1,COG1539@2 NA|NA|NA H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin KIAJIJGH_01421 334390.LAF_1342 4e-119 434.1 Lactobacillaceae ko:K07052 ko00000 Bacteria 1VFRX@1239,3F4Q0@33958,4HRQQ@91061,COG1266@1,COG1266@2 NA|NA|NA S CAAX protease self-immunity KIAJIJGH_01422 334390.LAF_1343 2.4e-181 641.3 Lactobacillaceae rbsR ko:K02529 ko00000,ko03000 Bacteria 1TQ7K@1239,3F44Q@33958,4HE07@91061,COG1609@1,COG1609@2 NA|NA|NA K Periplasmic binding proteins and sugar binding domain of LacI family KIAJIJGH_01423 334390.LAF_1344 5.2e-110 403.7 Lactobacillaceae Bacteria 1U5EA@1239,29NQX@1,309NV@2,3F5Q3@33958,4IF5Q@91061 NA|NA|NA KIAJIJGH_01424 334390.LAF_1345 8.6e-116 422.9 Lactobacillaceae dck 2.7.1.74 ko:K00893 ko00230,ko00240,ko01100,map00230,map00240,map01100 R00185,R01666 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TPJ1@1239,3F4MY@33958,4HA9N@91061,COG1428@1,COG1428@2 NA|NA|NA F deoxynucleoside kinase KIAJIJGH_01425 334390.LAF_1346 3.9e-156 557.8 Lactobacillaceae 3.2.1.17 ko:K01185,ko:K02395 ko00000,ko01000,ko02035 Bacteria 1UYRM@1239,3FC1U@33958,4HVMB@91061,COG1705@1,COG1705@2 NA|NA|NA NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase KIAJIJGH_01426 334390.LAF_1347 6.9e-229 799.7 Lactobacillaceae Bacteria 1TQMA@1239,3F3QW@33958,4HDTN@91061,COG1376@1,COG1376@2 NA|NA|NA S Putative peptidoglycan binding domain KIAJIJGH_01428 334390.LAF_1348 1.5e-86 325.5 Lactobacillaceae uspA ko:K03499,ko:K06149 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1VMC9@1239,3F6UZ@33958,4HYXY@91061,COG0589@1,COG0589@2 NA|NA|NA T Belongs to the universal stress protein A family KIAJIJGH_01429 334390.LAF_1349 2.6e-274 950.7 Lactobacillaceae pepV 3.5.1.18 ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 M00016 R00899,R02734,R04951 RC00064,RC00090,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002 Bacteria 1TPEG@1239,3F3UV@33958,4HC14@91061,COG0624@1,COG0624@2 NA|NA|NA E dipeptidase PepV KIAJIJGH_01430 334390.LAF_1350 2.4e-156 558.1 Lactobacillaceae nnrD 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 ko00000,ko01000 Bacteria 1TNZE@1239,3F480@33958,4HBZC@91061,COG0063@1,COG0063@2 NA|NA|NA H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration KIAJIJGH_01431 334390.LAF_1351 4.7e-61 240.4 Bacilli 3.2.1.23 ko:K12308 ko00052,map00052 R01105 RC00452 ko00000,ko00001,ko01000 Bacteria 1VPXG@1239,4HRCS@91061,COG3439@1,COG3439@2 NA|NA|NA S Domain of unknown function DUF302 KIAJIJGH_01432 334390.LAF_1352 6.8e-298 1029.2 Lactobacillaceae ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03328,ko:K06409 ko00000,ko02000 2.A.66.2,2.A.66.2.14 Bacteria 1TNYX@1239,3F404@33958,4H9RY@91061,COG2244@1,COG2244@2 NA|NA|NA S Polysaccharide biosynthesis protein KIAJIJGH_01433 334390.LAF_1353 2.6e-42 177.6 Lactobacillaceae Bacteria 1U6RI@1239,28VX1@1,30AJ1@2,3F8D4@33958,4IGIY@91061 NA|NA|NA KIAJIJGH_01434 334390.LAF_1592 2.3e-220 771.9 Lactobacillaceae Bacteria 1TQ62@1239,3F3YQ@33958,4HAJ1@91061,COG1061@1,COG1061@2,COG3886@1,COG3886@2 NA|NA|NA L Helicase C-terminal domain protein KIAJIJGH_01435 334390.LAF_1591 1.6e-54 218.4 Lactobacillaceae Bacteria 1VA3E@1239,3F7T0@33958,4HKDQ@91061,COG1694@1,COG1694@2 NA|NA|NA S MazG-like family KIAJIJGH_01436 334390.LAF_1590 4.7e-108 397.1 Lactobacillaceae lssY 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 1U506@1239,3F3M2@33958,4IES2@91061,COG0671@1,COG0671@2 NA|NA|NA I Acid phosphatase homologues KIAJIJGH_01437 334390.LAF_1589 5.9e-199 699.9 Lactobacillaceae pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0017057,GO:0044424,GO:0044444,GO:0044464,GO:0052689 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ3J@1239,3F3RC@33958,4HBHB@91061,COG2706@1,COG2706@2 NA|NA|NA G Lactonase, 7-bladed beta-propeller KIAJIJGH_01438 334390.LAF_1588 2e-97 361.7 Lactobacillaceae Bacteria 1U64T@1239,29P54@1,30A3B@2,3F71V@33958,4IFUC@91061 NA|NA|NA KIAJIJGH_01439 334390.LAF_1587 5.8e-225 786.6 Lactobacillaceae dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 1TQN0@1239,3F43S@33958,4HBD4@91061,COG1686@1,COG1686@2 NA|NA|NA M Belongs to the peptidase S11 family KIAJIJGH_01440 334390.LAF_1586 1.3e-168 599.0 Lactobacillaceae ponA Bacteria 1VBZ3@1239,3F672@33958,4HN99@91061,COG2367@1,COG2367@2 NA|NA|NA V Beta-lactamase enzyme family KIAJIJGH_01441 334390.LAF_1585 6.2e-266 922.9 Lactobacillaceae yjeM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 Bacteria 1TRFS@1239,3F4J0@33958,4HA0N@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino Acid KIAJIJGH_01443 334390.LAF_1584 5.5e-112 410.2 Lactobacillaceae Bacteria 1U6T2@1239,29PMW@1,30AK2@2,3F8FW@33958,4IGKT@91061 NA|NA|NA KIAJIJGH_01444 334390.LAF_1583 1.4e-159 568.9 Lactobacillaceae Bacteria 1TQQR@1239,3F59Q@33958,4HDT2@91061,COG2326@1,COG2326@2 NA|NA|NA S Polyphosphate nucleotide phosphotransferase, PPK2 family KIAJIJGH_01445 334390.LAF_1582 3.2e-164 584.3 Lactobacillaceae Bacteria 1TT5B@1239,3F5CC@33958,4HK1M@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain KIAJIJGH_01446 334390.LAF_1581 4.7e-260 903.3 Lactobacillaceae Bacteria 1UCBA@1239,3F3JA@33958,4HBCI@91061,COG4320@1,COG4320@2 NA|NA|NA S Uncharacterized protein conserved in bacteria (DUF2252) KIAJIJGH_01447 334390.LAF_1580 4.5e-301 1039.6 Lactobacillaceae scrB 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 GH32 Bacteria 1TPAE@1239,3F4UD@33958,4H9Y7@91061,COG1621@1,COG1621@2 NA|NA|NA G invertase KIAJIJGH_01448 334390.LAF_1579 1.2e-196 692.2 Lactobacillaceae adhA 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 Bacteria 1TP5B@1239,3F599@33958,4HVD8@91061,COG1064@1,COG1064@2 NA|NA|NA C Zinc-binding alcohol dehydrogenase family protein KIAJIJGH_01449 334390.LAF_1578 0.0 1202.2 Lactobacillaceae scrA 2.7.1.211,5.3.1.1 ko:K01803,ko:K02808,ko:K02809,ko:K02810 ko00010,ko00051,ko00500,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko02060,map00010,map00051,map00500,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map02060 M00001,M00002,M00003,M00269 R00811,R01015 RC00017,RC00423,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko04147 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 Bacteria 1TP5X@1239,3F458@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system KIAJIJGH_01450 334390.LAF_1577 3.6e-108 397.5 Lactobacillaceae ppiB GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K01802,ko:K03768 ko00000,ko01000,ko03110 Bacteria 1TRHW@1239,3F3TI@33958,4H9V0@91061,COG0652@1,COG0652@2 NA|NA|NA G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides KIAJIJGH_01451 334390.LAF_1772 3.5e-120 437.6 Lactobacillaceae ribA 3.5.4.25,4.1.99.12 ko:K01497,ko:K14652 ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 Bacteria 1U24A@1239,3F4KE@33958,4IBMV@91061,COG0108@1,COG0108@2 NA|NA|NA H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate KIAJIJGH_01452 1487921.DP68_11445 2.2e-16 92.0 Clostridia Bacteria 1UTEI@1239,252MS@186801,2A56C@1,30TV9@2 NA|NA|NA KIAJIJGH_01453 334390.LAF_1774 2.1e-63 248.1 Lactobacillaceae yjbR Bacteria 1VBCB@1239,3F734@33958,4HHQI@91061,COG2315@1,COG2315@2 NA|NA|NA S YjbR KIAJIJGH_01454 334390.LAF_1775 2.6e-115 421.4 Lactobacillaceae ko:K07126 ko00000 Bacteria 1UV8G@1239,3F8T0@33958,4IGUH@91061,COG0790@1,COG0790@2 NA|NA|NA S Sel1-like repeats. KIAJIJGH_01455 537007.BLAHAN_06914 8.5e-62 243.8 Blautia Bacteria 1V36C@1239,24933@186801,3Y29D@572511,COG1476@1,COG1476@2 NA|NA|NA K Psort location CytoplasmicMembrane, score KIAJIJGH_01456 537007.BLAHAN_06914 1.8e-20 105.1 Blautia Bacteria 1V36C@1239,24933@186801,3Y29D@572511,COG1476@1,COG1476@2 NA|NA|NA K Psort location CytoplasmicMembrane, score KIAJIJGH_01457 633697.EubceDRAFT1_2442 7.1e-83 313.5 Eubacteriaceae Bacteria 1UMFM@1239,25B9M@186801,25ZRK@186806,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins KIAJIJGH_01458 334390.LAF_1469 2e-169 601.7 Lactobacillaceae rumA GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 ko:K03215 ko00000,ko01000,ko03009 Bacteria 1TP4H@1239,3F41R@33958,4HA6M@91061,COG2265@1,COG2265@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family KIAJIJGH_01459 525309.HMPREF0494_0912 0.0 1651.3 Bacilli hsdR 3.1.21.3 ko:K01153 ko00000,ko01000,ko02048 Bacteria 1TP7S@1239,4HARG@91061,COG0610@1,COG0610@2 NA|NA|NA L COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases KIAJIJGH_01460 1262915.BN574_01390 1.8e-88 333.2 Negativicutes 3.1.21.3 ko:K01154 ko00000,ko01000,ko02048 Bacteria 1V24U@1239,4H74X@909932,COG0732@1,COG0732@2 NA|NA|NA V Type I restriction modification DNA specificity domain KIAJIJGH_01461 1033837.WANG_0932 5.2e-268 930.2 Lactobacillaceae bglP 2.7.1.211 ko:K02755,ko:K02756,ko:K02757,ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269,M00271 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9 Bacteria 1TP5X@1239,3F458@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system KIAJIJGH_01462 1033837.WANG_0933 2e-112 412.1 Lactobacillaceae licT ko:K02538,ko:K03488 ko00000,ko03000 Bacteria 1TQJJ@1239,3FB5Q@33958,4HBB3@91061,COG3711@1,COG3711@2 NA|NA|NA K CAT RNA binding domain KIAJIJGH_01463 908339.HMPREF9265_1262 8.5e-59 233.4 Lactobacillaceae Bacteria 1UPYG@1239,2CM2Y@1,32S6V@2,3F6IZ@33958,4IVDC@91061 NA|NA|NA S Domain of unknown function (DUF3841) KIAJIJGH_01464 1423807.BACO01000037_gene1099 1.4e-183 649.0 Lactobacillaceae ycsG Bacteria 1TP0Q@1239,3F582@33958,4HAYE@91061,COG1914@1,COG1914@2 NA|NA|NA P Natural resistance-associated macrophage protein KIAJIJGH_01465 1423807.BACO01000037_gene1098 5.8e-111 407.1 Lactobacillaceae ycsF ko:K07160 ko00000 Bacteria 1TR8X@1239,3F3Q3@33958,4H9PF@91061,COG1540@1,COG1540@2 NA|NA|NA S LamB/YcsF family KIAJIJGH_01466 1423807.BACO01000037_gene1097 4.5e-130 470.7 Lactobacillaceae ycsI Bacteria 1TRY8@1239,3F5JX@33958,4HCWD@91061,COG4336@1,COG4336@2 NA|NA|NA S Protein of unknown function (DUF1445) KIAJIJGH_01467 334390.LAF_1611 4.9e-257 893.3 Lactobacillaceae accC GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 iSF_1195.SF3294 Bacteria 1TP16@1239,3F3PT@33958,4HARK@91061,COG0439@1,COG0439@2 NA|NA|NA I Acetyl-CoA carboxylase biotin carboxylase subunit KIAJIJGH_01468 334390.LAF_1610 2.5e-58 231.5 Lactobacillaceae accB 2.3.1.12,4.1.1.3 ko:K00627,ko:K01571,ko:K02160 ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00307,M00376 R00209,R00217,R00742,R02569 RC00004,RC00040,RC00367,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000,ko02000 3.B.1.1.1 Bacteria 1VH23@1239,3F7QZ@33958,4HQHP@91061,COG0511@1,COG0511@2 NA|NA|NA I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA KIAJIJGH_01469 334390.LAF_1609 4.2e-189 667.2 Lactobacillaceae kipA 6.3.4.6 ko:K01941,ko:K06350 ko00220,ko00791,ko01100,map00220,map00791,map01100 R00774 RC00378 ko00000,ko00001,ko01000 Bacteria 1TR6U@1239,3F545@33958,4HACC@91061,COG1984@1,COG1984@2 NA|NA|NA E Allophanate hydrolase subunit 2 KIAJIJGH_01470 334390.LAF_1608 4.6e-134 483.8 Lactobacillaceae ybgJ 3.5.1.54 ko:K01457,ko:K06351,ko:K07160 ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120 R00005 RC02756 ko00000,ko00001,ko01000 Bacteria 1TTBZ@1239,3F64P@33958,4HHJJ@91061,COG2049@1,COG2049@2 NA|NA|NA E Allophanate hydrolase subunit 1 KIAJIJGH_01471 334390.LAF_1607 2.8e-70 271.2 Lactobacillaceae Bacteria 1V3QI@1239,3F7ID@33958,4HH53@91061,COG0789@1,COG0789@2 NA|NA|NA K helix_turn_helix, mercury resistance KIAJIJGH_01472 334390.LAF_1606 1.7e-81 308.5 Lactobacillaceae Bacteria 1V7RA@1239,2DMPJ@1,32SWG@2,3F7QU@33958,4IG6C@91061 NA|NA|NA S Psort location Cytoplasmic, score KIAJIJGH_01473 334390.LAF_1605 4.7e-285 986.5 Lactobacillaceae dinB 2.7.7.7 ko:K02346,ko:K03502,ko:K14161 ko00000,ko01000,ko03400 Bacteria 1TP42@1239,3FCBJ@33958,4HFGA@91061,COG0389@1,COG0389@2 NA|NA|NA L impB/mucB/samB family C-terminal domain KIAJIJGH_01474 334390.LAF_1604 6.9e-95 353.2 Lactobacillaceae wecD Bacteria 1V6Z8@1239,3F6WQ@33958,4HMP7@91061,COG0454@1,COG0456@2 NA|NA|NA K Acetyltransferase (GNAT) family KIAJIJGH_01475 334390.LAF_1603 6.4e-105 386.7 Lactobacillaceae 3.2.1.17 ko:K01185,ko:K02395 ko00000,ko01000,ko02035 Bacteria 1V7JY@1239,3F65T@33958,4I2AJ@91061,COG1705@1,COG1705@2 NA|NA|NA NU mannosyl-glycoprotein KIAJIJGH_01476 334390.LAF_1602 2.3e-195 688.0 Lactobacillaceae asnA GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 R00483 RC00010 ko00000,ko00001,ko01000 iAPECO1_1312.APECO1_2719,iECOK1_1307.ECOK1_4193,iECS88_1305.ECS88_4166,iUMN146_1321.UM146_18910,iUTI89_1310.UTI89_C4299 Bacteria 1TP28@1239,3F40A@33958,4HAEC@91061,COG2502@1,COG2502@2 NA|NA|NA F aspartate--ammonia ligase KIAJIJGH_01477 334390.LAF_1601 4.9e-215 753.4 Lactobacillaceae 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPDQ@1239,3F49P@33958,4HADW@91061,COG0620@1,COG0620@2 NA|NA|NA E methionine synthase, vitamin-B12 independent KIAJIJGH_01478 334390.LAF_1600 3e-89 334.3 Lactobacillaceae luxS GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009116,GO:0009119,GO:0009372,GO:0009987,GO:0010699,GO:0016053,GO:0016829,GO:0016846,GO:0017144,GO:0019284,GO:0019752,GO:0023052,GO:0033353,GO:0034641,GO:0042278,GO:0043094,GO:0043102,GO:0043436,GO:0043768,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046128,GO:0046394,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0051704,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 iECIAI39_1322.ECIAI39_2877,iPC815.YPO3300 Bacteria 1V1CH@1239,3F4W2@33958,4HFPR@91061,COG1854@1,COG1854@2 NA|NA|NA H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) KIAJIJGH_01479 334390.LAF_1599 5e-37 159.8 Lactobacillaceae Bacteria 1V64Y@1239,3F812@33958,4HNUM@91061,COG4892@1,COG4892@2 NA|NA|NA S Cytochrome B5 KIAJIJGH_01482 862514.HMPREF0623_1039 2.1e-15 89.7 Lactobacillaceae Bacteria 1VDDQ@1239,2C9UQ@1,32RPZ@2,3F5X9@33958,4HNJB@91061 NA|NA|NA S Domain of unknown function (DUF4811) KIAJIJGH_01483 334390.LAF_1595 2.5e-63 248.1 Lactobacillaceae lmrB Bacteria 1TPRN@1239,3F4A2@33958,4H9VV@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily KIAJIJGH_01484 334390.LAF_1595 1e-137 496.1 Lactobacillaceae lmrB Bacteria 1TPRN@1239,3F4A2@33958,4H9VV@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily KIAJIJGH_01485 334390.LAF_1594 2.5e-95 354.8 Lactobacillaceae Bacteria 1VI1M@1239,3F530@33958,4HPZV@91061,COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator KIAJIJGH_01486 1203076.CAKF01000020_gene1644 8.6e-276 956.1 Lactobacillaceae lacS GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03292,ko:K11104,ko:K16209 ko00000,ko02000 2.A.2,2.A.2.1,2.A.2.2 Bacteria 1TRA5@1239,3F3P7@33958,4HCDS@91061,COG2190@1,COG2190@2,COG2211@1,COG2211@2 NA|NA|NA G Transporter KIAJIJGH_01487 1203076.CAKF01000020_gene1643 0.0 1108.2 Lactobacillaceae rafA 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 Bacteria 1TQF4@1239,3F3RU@33958,4HA5R@91061,COG3345@1,COG3345@2 NA|NA|NA G alpha-galactosidase KIAJIJGH_01488 334390.LAF_1790 2.1e-180 638.3 Lactobacillaceae galR ko:K02529 ko00000,ko03000 Bacteria 1TPZJ@1239,3F3PB@33958,4HC9Z@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator KIAJIJGH_01489 334390.LAF_1791 3.1e-286 990.3 Lactobacillaceae galT 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPBN@1239,3F4D8@33958,4HAYJ@91061,COG4468@1,COG4468@2 NA|NA|NA G UDP-glucose--hexose-1-phosphate uridylyltransferase KIAJIJGH_01490 334390.LAF_1792 3.9e-223 780.4 Lactobacillaceae galK GO:0005975,GO:0005996,GO:0006012,GO:0008150,GO:0008152,GO:0019318,GO:0044238,GO:0044281,GO:0071704 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TPD0@1239,3F3Q9@33958,4HARP@91061,COG0153@1,COG0153@2 NA|NA|NA F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) KIAJIJGH_01491 334390.LAF_1793 1.2e-182 645.6 Lactobacillaceae celE GO:0000272,GO:0001871,GO:0003674,GO:0003824,GO:0004553,GO:0005488,GO:0005975,GO:0005976,GO:0006073,GO:0006080,GO:0008150,GO:0008152,GO:0008810,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010391,GO:0010410,GO:0016052,GO:0016787,GO:0016788,GO:0016798,GO:0017144,GO:0030243,GO:0030245,GO:0030246,GO:0030247,GO:0030248,GO:0042737,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0045491,GO:0045493,GO:0046555,GO:0051273,GO:0051275,GO:0052689,GO:0071554,GO:0071704,GO:1901575,GO:2000884 3.2.1.4 ko:K01179,ko:K20276 ko00500,ko01100,ko02024,map00500,map01100,map02024 R06200,R11307,R11308 ko00000,ko00001,ko01000 GH5,GH9 Bacteria 1U9HW@1239,3F4VR@33958,4HQ3R@91061,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase family KIAJIJGH_01492 334390.LAF_1794 1.6e-143 515.4 Lactobacillaceae ptp3 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1V851@1239,3F55V@33958,4HJB2@91061,COG2365@1,COG2365@2 NA|NA|NA T Tyrosine phosphatase family KIAJIJGH_01493 334390.LAF_1795 2.7e-96 357.8 Lactobacillaceae yxkA ko:K06910 ko00000 Bacteria 1VJEE@1239,3FBPI@33958,4IRQB@91061,COG1881@1,COG1881@2 NA|NA|NA S Phosphatidylethanolamine-binding protein KIAJIJGH_01494 334390.LAF_1796 6.9e-36 156.0 Lactobacillaceae Bacteria 1W6D0@1239,2930D@1,2ZQHQ@2,3F7KZ@33958,4HZS5@91061 NA|NA|NA KIAJIJGH_01495 334390.LAF_1797 6.6e-136 490.0 Lactobacillaceae glnQ 3.6.3.21 ko:K02028,ko:K10010 ko02010,map02010 M00234,M00236 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.10,3.A.1.3.14 Bacteria 1TNYD@1239,3F4YF@33958,4HUHS@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein KIAJIJGH_01496 334390.LAF_1798 5.3e-119 433.7 Lactobacillaceae tcyB GO:0000099,GO:0000101,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015184,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015811,GO:0015849,GO:0016020,GO:0022857,GO:0033229,GO:0034220,GO:0042883,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:0098655,GO:0098656,GO:1901682,GO:1902475,GO:1903712,GO:1903825,GO:1905039 ko:K02424,ko:K10009 ko02010,map02010 M00234 ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3.10,3.A.1.3.14 iYO844.BSU03600 Bacteria 1TPQ8@1239,3FC59@33958,4HV4G@91061,COG0765@1,COG0765@2 NA|NA|NA U Binding-protein-dependent transport system inner membrane component KIAJIJGH_01497 334390.LAF_1799 4.8e-140 503.8 Lactobacillaceae tcyA ko:K02424,ko:K10009,ko:K16957 ko02010,map02010 M00234,M00585 ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3.10,3.A.1.3.13,3.A.1.3.14 Bacteria 1TR13@1239,3F4MH@33958,4HBRP@91061,COG0834@1,COG0834@2 NA|NA|NA ET Belongs to the bacterial solute-binding protein 3 family KIAJIJGH_01498 334390.LAF_1800 2e-52 211.5 Lactobacillaceae Bacteria 1W304@1239,2905K@1,2ZMVG@2,3F7TH@33958,4I0TS@91061 NA|NA|NA KIAJIJGH_01499 334390.LAF_1801 3.1e-170 604.4 Lactobacillaceae MA20_03535 1.1.1.399,1.1.1.95 ko:K00058,ko:K04496 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,ko04310,ko04330,ko05200,ko05220,map00260,map00680,map01100,map01120,map01130,map01200,map01230,map04310,map04330,map05200,map05220 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1TPCX@1239,3F4Z6@33958,4HASY@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family KIAJIJGH_01500 334390.LAF_1802 1.7e-79 302.0 Lactobacillaceae greA ko:K03624,ko:K04760 ko00000,ko03021 Bacteria 1V1G3@1239,3F6ZK@33958,4HW8H@91061,COG0782@1,COG0782@2 NA|NA|NA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides KIAJIJGH_01501 334390.LAF_1803 5.9e-146 523.5 Lactobacillaceae pnuC ko:K03811 ko00000,ko02000 4.B.1.1 Bacteria 1VE5T@1239,3F3MB@33958,4HMNW@91061,COG3201@1,COG3201@2 NA|NA|NA H nicotinamide mononucleotide transporter KIAJIJGH_01502 334390.LAF_1804 1.1e-92 345.9 Lactobacillaceae ymdB Bacteria 1TPCU@1239,3F6GV@33958,4HIHC@91061,COG2110@1,COG2110@2 NA|NA|NA S Macro domain protein KIAJIJGH_01503 334390.LAF_1805 0.0 1275.8 Lactobacillaceae pepO 3.4.24.71 ko:K01415,ko:K07386 ko00000,ko01000,ko01002,ko04147 Bacteria 1TQTA@1239,3F4CX@33958,4HDSF@91061,COG3590@1,COG3590@2 NA|NA|NA O Peptidase family M13 KIAJIJGH_01504 334390.LAF_1806 3.1e-229 800.8 Lactobacillaceae pbuG ko:K06901 ko00000,ko02000 2.A.1.40 Bacteria 1TQC6@1239,3F44D@33958,4HANG@91061,COG2252@1,COG2252@2 NA|NA|NA S permease KIAJIJGH_01505 334390.LAF_1807 2.5e-46 191.0 Lactobacillaceae Bacteria 1U6RG@1239,2DKRV@1,30AIZ@2,3F8D1@33958,4IGIW@91061 NA|NA|NA KIAJIJGH_01506 334390.LAF_1808 2.9e-213 747.7 Lactobacillaceae Bacteria 1VE6N@1239,3F556@33958,4HMSF@91061,COG3864@1,COG3864@2 NA|NA|NA S Putative metallopeptidase domain KIAJIJGH_01507 334390.LAF_1809 5.5e-206 723.4 Lactobacillaceae 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1U8NZ@1239,3F53Z@33958,4HCYD@91061,COG0714@1,COG0714@2 NA|NA|NA S associated with various cellular activities KIAJIJGH_01508 334390.LAF_1810 1.3e-116 425.6 Lactobacillaceae mpg GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1V1E6@1239,3F59D@33958,4HG5E@91061,COG2094@1,COG2094@2 NA|NA|NA L Belongs to the DNA glycosylase MPG family KIAJIJGH_01509 334390.LAF_1811 6.8e-65 253.1 Lactobacillaceae yeaO Bacteria 1VABH@1239,3F715@33958,4HKI2@91061,COG3189@1,COG3189@2 NA|NA|NA S Protein of unknown function, DUF488 KIAJIJGH_01511 334390.LAF_1813 4.8e-125 453.8 Lactobacillaceae yrkL ko:K11748 ko00000,ko02000 2.A.37.1.2 Bacteria 1V4UF@1239,3F6XY@33958,4HIR3@91061,COG2249@1,COG2249@2 NA|NA|NA S Flavodoxin-like fold KIAJIJGH_01512 334390.LAF_1814 5.6e-55 219.9 Lactobacillaceae Bacteria 1VZZV@1239,2CCD8@1,348YF@2,3F79R@33958,4HZ8C@91061 NA|NA|NA KIAJIJGH_01513 334390.LAF_1815 2.2e-108 398.3 Lactobacillaceae nnrD 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 ko00000,ko01000 Bacteria 1V9F4@1239,3F5N4@33958,4IS4H@91061,COG0062@1,COG0062@2 NA|NA|NA H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX KIAJIJGH_01514 334390.LAF_1816 1e-96 359.4 Lactobacillaceae efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K02356 ko00000,ko03012 Bacteria 1TR8P@1239,3F422@33958,4H9YX@91061,COG0231@1,COG0231@2 NA|NA|NA J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase KIAJIJGH_01515 334390.LAF_1817 5.4e-102 377.1 Lactobacillaceae Bacteria 1U55V@1239,29DQI@1,300NC@2,3F4UQ@33958,4IEX6@91061 NA|NA|NA KIAJIJGH_01516 334390.LAF_1818 9.5e-26 122.1 Bacilli Bacteria 1W51D@1239,29A0B@1,2ZX1X@2,4I0QW@91061 NA|NA|NA KIAJIJGH_01517 334390.LAF_1819 3.8e-168 597.4 Lactobacillaceae scrR ko:K02529,ko:K03484 ko00000,ko03000 Bacteria 1TQ7K@1239,3F4JE@33958,4H9V1@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator, LacI family KIAJIJGH_01518 334390.LAF_1747 0.0 1302.7 Lactobacillaceae xfp 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 Bacteria 1TR23@1239,3F3TZ@33958,4HC2J@91061,COG3957@1,COG3957@2 NA|NA|NA G Phosphoketolase KIAJIJGH_01519 257314.LJ_0722 1.4e-44 186.0 Lactobacillaceae mdtG GO:0006810,GO:0006855,GO:0008150,GO:0015893,GO:0042221,GO:0042493,GO:0050896,GO:0051179,GO:0051234,GO:0055085 ko:K08161 ko00000,ko02000 2.A.1.2.20 Bacteria 1TRDJ@1239,3FCA7@33958,4H9UE@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily KIAJIJGH_01520 1203076.CAKF01000021_gene1512 4e-51 207.6 Lactobacillaceae mdtG GO:0006810,GO:0006855,GO:0008150,GO:0015893,GO:0042221,GO:0042493,GO:0050896,GO:0051179,GO:0051234,GO:0055085 ko:K08161 ko00000,ko02000 2.A.1.2.20 Bacteria 1TRDJ@1239,3FCA7@33958,4H9UE@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily KIAJIJGH_01521 334390.LAF_0204 6e-41 172.9 Lactobacillaceae rpmE2 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034224,GO:0034641,GO:0034645,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0120127,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02909 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VEGU@1239,3F7D7@33958,4HKF0@91061,COG0254@1,COG0254@2 NA|NA|NA J Ribosomal protein L31 KIAJIJGH_01522 334390.LAF_0203 2.3e-237 827.8 Lactobacillaceae murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 R00660 RC00350 ko00000,ko00001,ko01000,ko01011 iYO844.BSU37100 Bacteria 1TPAU@1239,3F3P8@33958,4H9KI@91061,COG0766@1,COG0766@2 NA|NA|NA M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine KIAJIJGH_01523 334390.LAF_0202 1.1e-310 1071.6 Lactobacillaceae pyrG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS01075,iNJ661.Rv1699 Bacteria 1TP34@1239,3F42X@33958,4H9X6@91061,COG0504@1,COG0504@2 NA|NA|NA F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates KIAJIJGH_01524 334390.LAF_0201 1.6e-47 196.1 Lactobacillaceae rpoE GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Bacteria 1V6WX@1239,3F55D@33958,4HIUK@91061,COG3343@1,COG3343@2 NA|NA|NA K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling KIAJIJGH_01525 334390.LAF_0200 3.2e-74 284.3 Lactobacillaceae ywiB Bacteria 1V8IZ@1239,3F6AI@33958,4HIW0@91061,COG4506@1,COG4506@2 NA|NA|NA S Domain of unknown function (DUF1934) KIAJIJGH_01526 334390.LAF_0199 5.7e-266 922.9 Lactobacillaceae ywfO GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 ko:K06885 ko00000 Bacteria 1TPVB@1239,3F442@33958,4HAX8@91061,COG1078@1,COG1078@2 NA|NA|NA S HD domain protein KIAJIJGH_01527 334390.LAF_0198 1.5e-141 508.8 Lactobacillaceae yxeH Bacteria 1TR16@1239,3F55S@33958,4HCZ6@91061,COG0561@1,COG0561@2 NA|NA|NA S hydrolase KIAJIJGH_01528 334390.LAF_0197 5.9e-29 132.9 Lactobacillaceae Bacteria 1U5XS@1239,29P09@1,309YE@2,3F6NK@33958,4IFM1@91061 NA|NA|NA KIAJIJGH_01529 334390.LAF_0196 9.7e-175 619.4 Lactobacillaceae prs 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_2848 Bacteria 1TQ6Q@1239,3F3U2@33958,4HB61@91061,COG0462@1,COG0462@2 NA|NA|NA F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) KIAJIJGH_01530 334390.LAF_0195 2.8e-204 718.0 Lactobacillaceae glmU GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030203,GO:0030260,GO:0033692,GO:0034637,GO:0034645,GO:0035635,GO:0040007,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042,ko:K11528 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP88@1239,3F4I3@33958,4H9V5@91061,COG1207@1,COG1207@2 NA|NA|NA M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain KIAJIJGH_01531 334390.LAF_0194 7.5e-152 543.1 Lactobacillaceae purR 2.4.2.22,2.4.2.7 ko:K00759,ko:K03816,ko:K09685 ko00230,ko01100,ko01110,map00230,map01100,map01110 R00190,R01229,R02142,R04378 RC00063,RC00122 ko00000,ko00001,ko01000,ko03000,ko04147 Bacteria 1TPN9@1239,3F3NH@33958,4HB8I@91061,COG0503@1,COG0503@2 NA|NA|NA F pur operon repressor KIAJIJGH_01532 334390.LAF_0193 3.2e-128 464.5 Lactobacillaceae znuB ko:K02075,ko:K09816 ko02010,map02010 M00242,M00244 ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 Bacteria 1V0SX@1239,3FC75@33958,4HTE9@91061,COG1108@1,COG1108@2 NA|NA|NA U ABC 3 transport family KIAJIJGH_01533 334390.LAF_0192 5.4e-95 353.6 Lactobacillaceae fhuC ko:K02074,ko:K09817 ko02010,map02010 M00242,M00244 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 Bacteria 1TQ68@1239,3F49M@33958,4HAZI@91061,COG1121@1,COG1121@2 NA|NA|NA P ABC transporter KIAJIJGH_01534 334390.LAF_0191 1.2e-166 592.4 Lactobacillaceae znuA ko:K02077 M00244 ko00000,ko00002,ko02000 3.A.1.15 Bacteria 1V110@1239,3FBJR@33958,4HZ7G@91061,COG0803@1,COG0803@2 NA|NA|NA P Belongs to the bacterial solute-binding protein 9 family KIAJIJGH_01535 334390.LAF_0190 1.3e-159 568.9 Lactobacillaceae ispE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.1.1.182,2.7.1.148 ko:K00919,ko:K02528,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096,M00582 R05634,R10716 RC00002,RC00003,RC01439,RC03257 ko00000,ko00001,ko00002,ko01000,ko02000,ko03009 3.A.1.29 iEC55989_1330.EC55989_1304,iLJ478.TM1383,iYO844.BSU00460 Bacteria 1TPXV@1239,3F43W@33958,4HAV8@91061,COG1947@1,COG1947@2 NA|NA|NA F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol KIAJIJGH_01536 334390.LAF_0189 3.6e-160 570.9 Lactobacillaceae ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 R10716 RC00003,RC03257 ko00000,ko01000,ko03009 Bacteria 1TP9W@1239,3F3VC@33958,4HA4R@91061,COG0030@1,COG0030@2 NA|NA|NA J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits KIAJIJGH_01537 334390.LAF_0188 2.9e-99 367.9 Lactobacillaceae rnmV GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 ko:K05985,ko:K07476 ko00000,ko01000 Bacteria 1V3K3@1239,3F64F@33958,4HH5Y@91061,COG1658@1,COG1658@2 NA|NA|NA J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step KIAJIJGH_01538 334390.LAF_0187 1.8e-147 528.5 Lactobacillaceae tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 ko:K03424 ko00000,ko01000 Bacteria 1TNY1@1239,3F3N2@33958,4HA74@91061,COG0084@1,COG0084@2 NA|NA|NA L hydrolase, TatD family KIAJIJGH_01539 334390.LAF_0186 0.0 1338.2 Lactobacillaceae metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPA1@1239,3F3XR@33958,4H9VC@91061,COG0143@1,COG0143@2 NA|NA|NA J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation KIAJIJGH_01540 334390.LAF_0185 8.1e-162 576.2 Lactobacillaceae yunF Bacteria 1TPX4@1239,3F40Y@33958,4HA0X@91061,COG1801@1,COG1801@2 NA|NA|NA F Protein of unknown function DUF72 KIAJIJGH_01541 334390.LAF_0184 1.2e-211 742.3 Lactobacillaceae norA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K08153,ko:K19576,ko:K19578 M00717,M00765 ko00000,ko00002,ko02000 2.A.1.2.10,2.A.1.2.70,2.A.1.2.8 Bacteria 1TS6K@1239,3F4X1@33958,4HB1V@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily KIAJIJGH_01542 334390.LAF_0183 4.4e-129 467.2 Lactobacillaceae cobB ko:K12410 ko00000,ko01000 Bacteria 1TQKD@1239,3F4WS@33958,4HC4I@91061,COG0846@1,COG0846@2 NA|NA|NA K SIR2 family KIAJIJGH_01543 334390.LAF_0182 1.2e-185 655.6 Lactobacillaceae Bacteria 1VT7R@1239,296WI@1,2ZU5A@2,3F4R1@33958,4HVBN@91061 NA|NA|NA KIAJIJGH_01544 334390.LAF_0181 4.6e-217 760.4 Lactobacillaceae mvaA 1.1.1.34,1.1.1.88,2.3.1.9 ko:K00021,ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,ko04152,ko04976,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020,map04152,map04976 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081,R02082 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1TPNY@1239,3F3YY@33958,4HBQ3@91061,COG1257@1,COG1257@2 NA|NA|NA C Belongs to the HMG-CoA reductase family KIAJIJGH_01545 334390.LAF_0180 1.3e-171 609.0 Lactobacillaceae ppx 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 R03409 RC00002 ko00000,ko00001,ko01000 Bacteria 1TS3I@1239,3F3SR@33958,4HAQS@91061,COG0248@1,COG0248@2 NA|NA|NA FP exopolyphosphatase KIAJIJGH_01546 334390.LAF_0179 0.0 1495.3 Lactobacillaceae helD 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TP39@1239,3F486@33958,4H9Y5@91061,COG3973@1,COG3973@2 NA|NA|NA L DNA helicase KIAJIJGH_01547 334390.LAF_0178 4.5e-203 713.8 Lactobacillaceae napA GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0009847,GO:0015075,GO:0015077,GO:0015081,GO:0015291,GO:0015297,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032502,GO:0034220,GO:0035725,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662 Bacteria 1TS32@1239,3F3QK@33958,4HAGC@91061,COG0475@1,COG0475@2 NA|NA|NA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family KIAJIJGH_01548 334390.LAF_0177 4.3e-155 553.9 Lactobacillaceae metQ_4 ko:K02073 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1V0Z6@1239,3FC6K@33958,4HBBW@91061,COG1464@1,COG1464@2 NA|NA|NA P Belongs to the nlpA lipoprotein family KIAJIJGH_01550 334390.LAF_0174 2.1e-140 505.0 Lactobacillaceae nfrA 1.5.1.38,1.5.1.39 ko:K19285,ko:K19286 ko00740,ko01100,map00740,map01100 R05705,R05706 RC00126 ko00000,ko00001,ko01000 Bacteria 1UB8S@1239,3F4IY@33958,4HEGP@91061,COG0778@1,COG0778@2 NA|NA|NA C nitroreductase KIAJIJGH_01551 1203076.CAKF01000021_gene1483 6.6e-24 117.5 Bacteria phaG ko:K18100 ko02024,ko02025,map02024,map02025 ko00000,ko00001,ko01000,ko01003 GT1 Bacteria COG2267@1,COG2267@2 NA|NA|NA I carboxylic ester hydrolase activity KIAJIJGH_01552 334390.LAF_0172 4e-60 237.3 Lactobacillaceae ko:K02051 M00188 ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 Bacteria 1UZXK@1239,3F41Q@33958,4HUWT@91061,COG0583@1,COG0583@2 NA|NA|NA K Transcriptional regulator KIAJIJGH_01553 334390.LAF_0170 0.0 1676.8 Lactobacillaceae pepN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.2 ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 Bacteria 1TR43@1239,3F3UH@33958,4HA20@91061,COG0308@1,COG0308@2 NA|NA|NA E aminopeptidase KIAJIJGH_01554 334390.LAF_0169 5.2e-195 686.8 Lactobacillaceae 1.1.1.1,1.1.1.14 ko:K00001,ko:K00008 ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 M00014 R00623,R00754,R00875,R01896,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00085,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPIW@1239,3F42F@33958,4HB2G@91061,COG1063@1,COG1063@2 NA|NA|NA E alcohol dehydrogenase KIAJIJGH_01555 334390.LAF_0168 2.3e-53 214.5 Lactobacillaceae Bacteria 1VFER@1239,3F7BQ@33958,4HM4N@91061,COG1694@1,COG1694@2 NA|NA|NA S Mazg nucleotide pyrophosphohydrolase KIAJIJGH_01556 334390.LAF_0167 2.3e-136 491.5 Lactobacillaceae Bacteria 1V4VT@1239,3F4P8@33958,4HXCK@91061,COG2755@1,COG2755@2 NA|NA|NA E GDSL-like Lipase/Acylhydrolase family KIAJIJGH_01557 334390.LAF_0166 1.1e-123 449.1 Lactobacillaceae Bacteria 1V6AG@1239,3F6YM@33958,4HN5N@91061,COG0778@1,COG0778@2 NA|NA|NA C nitroreductase KIAJIJGH_01558 334390.LAF_0165 1.9e-175 621.7 Lactobacillaceae rihA GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006152,GO:0006213,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008477,GO:0009056,GO:0009116,GO:0009119,GO:0009164,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042454,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045437,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0047405,GO:0050263,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 3.2.2.1 ko:K01239,ko:K01250 ko00230,ko00760,ko01100,map00230,map00760,map01100 R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 iEC55989_1330.EC55989_0645,iECSE_1348.ECSE_0721,iEcE24377_1341.EcE24377A_0679,iSbBS512_1146.SbBS512_E0598 Bacteria 1TSSS@1239,3FB76@33958,4HEK7@91061,COG1957@1,COG1957@2 NA|NA|NA F Inosine-uridine preferring nucleoside hydrolase KIAJIJGH_01559 1267003.KB911418_gene901 8.5e-120 436.8 Lactobacillaceae arcC 2.7.2.2 ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 R00150,R01395 RC00002,RC00043,RC02803,RC02804 ko00000,ko00001,ko01000 Bacteria 1TP9H@1239,3F5QA@33958,4H9QD@91061,COG0549@1,COG0549@2 NA|NA|NA E Amino acid kinase family KIAJIJGH_01562 1423743.JCM14108_1792 1e-39 169.1 Lactobacillaceae sucD GO:0001539,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006928,GO:0008150,GO:0009361,GO:0009987,GO:0032991,GO:0040011,GO:0042709,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588,GO:1902494 6.2.1.5 ko:K01902,ko:K02381 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHQ6@1239,3F63J@33958,4H9VN@91061,COG0074@1,COG0074@2 NA|NA|NA C Protein of unknown function (DUF1116) KIAJIJGH_01563 1423734.JCM14202_2246 7.5e-69 266.9 Lactobacillaceae pucG GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588,R10908 RC00006,RC00008,RC00018,RC03305 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TPS0@1239,3FB94@33958,4HBDW@91061,COG0075@1,COG0075@2 NA|NA|NA E Aminotransferase class-V KIAJIJGH_01564 525318.HMPREF0497_1849 9.5e-63 246.5 Lactobacillaceae pucG GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588,R10908 RC00006,RC00008,RC00018,RC03305 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TPS0@1239,3FB94@33958,4HBDW@91061,COG0075@1,COG0075@2 NA|NA|NA E Aminotransferase class-V KIAJIJGH_01565 334390.LAF_0159 2.6e-180 637.9 Lactobacillaceae 1.1.1.26 ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko01000 Bacteria 1TPCX@1239,3F4Z6@33958,4HASY@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family KIAJIJGH_01566 334390.LAF_1828 2.3e-41 174.5 Lactobacillaceae mntH GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 ko:K03322 ko00000,ko02000 2.A.55.2.6,2.A.55.3 Bacteria 1TPT1@1239,3F49Y@33958,4HAEA@91061,COG1914@1,COG1914@2 NA|NA|NA P H( )-stimulated, divalent metal cation uptake system KIAJIJGH_01567 334390.LAF_1828 6.2e-29 132.9 Lactobacillaceae mntH GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 ko:K03322 ko00000,ko02000 2.A.55.2.6,2.A.55.3 Bacteria 1TPT1@1239,3F49Y@33958,4HAEA@91061,COG1914@1,COG1914@2 NA|NA|NA P H( )-stimulated, divalent metal cation uptake system KIAJIJGH_01568 334390.LAF_1828 2.1e-41 174.5 Lactobacillaceae mntH GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 ko:K03322 ko00000,ko02000 2.A.55.2.6,2.A.55.3 Bacteria 1TPT1@1239,3F49Y@33958,4HAEA@91061,COG1914@1,COG1914@2 NA|NA|NA P H( )-stimulated, divalent metal cation uptake system KIAJIJGH_01569 334390.LAF_1828 1.4e-32 145.2 Lactobacillaceae mntH GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 ko:K03322 ko00000,ko02000 2.A.55.2.6,2.A.55.3 Bacteria 1TPT1@1239,3F49Y@33958,4HAEA@91061,COG1914@1,COG1914@2 NA|NA|NA P H( )-stimulated, divalent metal cation uptake system KIAJIJGH_01570 334390.LAF_1827 9.3e-189 666.0 Lactobacillaceae tdh 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPWP@1239,3FC44@33958,4HVQZ@91061,COG1063@1,COG1063@2 NA|NA|NA E Alcohol dehydrogenase GroES-like domain KIAJIJGH_01571 334390.LAF_1826 8.2e-108 396.4 Lactobacillaceae ygfC Bacteria 1V4D3@1239,3F6ZM@33958,4HJ8Z@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family KIAJIJGH_01572 334390.LAF_1825 8.6e-158 563.1 Lactobacillaceae hrtB ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TWFZ@1239,3F3K5@33958,4H9RQ@91061,COG0577@1,COG0577@2 NA|NA|NA V ABC transporter permease KIAJIJGH_01573 334390.LAF_1824 5.5e-124 450.3 Lactobacillaceae devA 3.6.3.25 ko:K02003,ko:K06020,ko:K09810 ko02010,map02010 M00255,M00258 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.125 Bacteria 1TQP5@1239,3F4RP@33958,4HBXK@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein KIAJIJGH_01574 334390.LAF_0003 1.7e-34 151.4 Lactobacillaceae yaaA GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 ko:K14761 ko00000,ko03009 Bacteria 1VEJ2@1239,3F803@33958,4HNMC@91061,COG2501@1,COG2501@2 NA|NA|NA S S4 domain protein YaaA KIAJIJGH_01575 334390.LAF_0004 1.5e-203 715.3 Lactobacillaceae recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 Bacteria 1TP9U@1239,3F3Q1@33958,4HA0W@91061,COG1195@1,COG1195@2 NA|NA|NA L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP KIAJIJGH_01576 334390.LAF_0005 0.0 1280.8 Lactobacillaceae gyrB GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02470,ko:K02622 ko00000,ko01000,ko02048,ko03032,ko03036,ko03400 Bacteria 1TQ0R@1239,3F48M@33958,4H9Y6@91061,COG0187@1,COG0187@2 NA|NA|NA L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner KIAJIJGH_01577 334390.LAF_0002 3.8e-207 727.2 Lactobacillaceae dnaN 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Bacteria 1TQ7J@1239,3F3ZQ@33958,4H9TF@91061,COG0592@1,COG0592@2 NA|NA|NA L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria KIAJIJGH_01578 334390.LAF_0001 5.2e-248 863.2 Lactobacillaceae dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 Bacteria 1TPV7@1239,3F3YA@33958,4H9MW@91061,COG0593@1,COG0593@2 NA|NA|NA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids KIAJIJGH_01580 334390.LAF_1843 2.6e-14 83.6 Lactobacillaceae rpmH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02914 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1VK90@1239,3F81W@33958,4HR2Z@91061,COG0230@1,COG0230@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bL34 family KIAJIJGH_01581 334390.LAF_1842 1.4e-56 225.3 Lactobacillaceae rnpA GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536,ko:K08998 ko00000,ko01000,ko03016 Bacteria 1VA78@1239,3F6GS@33958,4HKG6@91061,COG0594@1,COG0594@2 NA|NA|NA J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme KIAJIJGH_01582 334390.LAF_1841 3.4e-144 517.7 Lactobacillaceae yidC ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 Bacteria 1TQ0J@1239,3F3SD@33958,4HB3J@91061,COG0706@1,COG0706@2 NA|NA|NA U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins KIAJIJGH_01583 334390.LAF_1840 4.8e-154 550.4 Lactobacillaceae jag ko:K06346 ko00000 Bacteria 1V3IN@1239,3F5WG@33958,4HHHU@91061,COG1847@1,COG1847@2 NA|NA|NA S R3H domain protein KIAJIJGH_01584 334390.LAF_1839 2.1e-252 877.9 Lactobacillaceae mnmE GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K03650 R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 Bacteria 1TPJF@1239,3F3WA@33958,4HA06@91061,COG0486@1,COG0486@2 NA|NA|NA S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 KIAJIJGH_01585 334390.LAF_1838 0.0 1246.1 Lactobacillaceae gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 ko:K03495 R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 Bacteria 1TQ4B@1239,3F454@33958,4HA6S@91061,COG0445@1,COG0445@2 NA|NA|NA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 KIAJIJGH_01586 1138822.PL11_10605 5e-287 993.0 Lactobacillaceae Bacteria 1TQST@1239,3F47D@33958,4HPQC@91061,COG4974@1,COG4974@2 NA|NA|NA L Transposase IS66 family KIAJIJGH_01587 1423724.BAMM01000040_gene2169 3.5e-281 975.3 Lactobacillaceae GO:0005575,GO:0005576 2.4.1.5 ko:K00689,ko:K20276 ko00500,ko02020,ko02024,map00500,map02020,map02024 R02120,R06066 RC00028 ko00000,ko00001,ko01000 GH13 Bacteria 1VQXK@1239,3F93W@33958,4HEIA@91061,COG0366@1,COG0366@2,COG5263@1,COG5263@2 NA|NA|NA G Glycosyl hydrolase family 70 KIAJIJGH_01588 575594.ACOH01000029_gene637 9.8e-77 292.7 Lactobacillaceae Bacteria 1V450@1239,2ZJ01@2,3F6T7@33958,4HFPA@91061,arCOG05874@1 NA|NA|NA KIAJIJGH_01589 334390.LAF_0778 3.6e-85 321.6 Lactobacillaceae Bacteria 1TQEG@1239,3F43M@33958,4HD6M@91061,COG2801@1,COG2801@2 NA|NA|NA L hmm pf00665 KIAJIJGH_01590 334390.LAF_1575 4.3e-47 194.9 Lactobacillaceae Bacteria 1V1QC@1239,3F65F@33958,4HH7E@91061,COG2963@1,COG2963@2 NA|NA|NA L Helix-turn-helix domain KIAJIJGH_01591 411469.EUBHAL_02648 1.2e-143 516.2 Eubacteriaceae ko:K22230 ko00562,ko01120,map00562,map01120 R09954 RC00182 ko00000,ko00001,ko01000 Bacteria 1TQSS@1239,249QZ@186801,25ZE9@186806,COG0673@1,COG0673@2 NA|NA|NA S Oxidoreductase family, NAD-binding Rossmann fold KIAJIJGH_01593 1423743.JCM14108_412 9.3e-205 719.5 Lactobacillaceae ko:K03458 ko00000 2.A.40 Bacteria 1TNZZ@1239,3FC8X@33958,4HCX6@91061,COG2233@1,COG2233@2 NA|NA|NA F Permease KIAJIJGH_01594 1423743.JCM14108_413 2.5e-166 591.7 Bacilli luxE 6.2.1.19 ko:K06046 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Bacteria 1UYJ0@1239,4HD80@91061,COG1541@1,COG1541@2 NA|NA|NA H Acyl-protein synthetase, LuxE KIAJIJGH_01595 1423743.JCM14108_414 3.6e-197 694.5 Bacilli luxC 1.2.1.50 ko:K03400 ko02020,ko02024,map02020,map02024 R10549 RC00004,RC00184 ko00000,ko00001,ko01000 Bacteria 1TSYP@1239,4HE2I@91061,COG1012@1,COG1012@2 NA|NA|NA C Acyl-CoA reductase (LuxC) KIAJIJGH_01596 1423743.JCM14108_415 2.7e-111 408.3 Lactobacillaceae Bacteria 1UU2F@1239,3F9TV@33958,4HCVI@91061,COG1028@1,COG1028@2 NA|NA|NA IQ KR domain KIAJIJGH_01597 334390.LAF_0074 2.2e-213 748.0 Lactobacillaceae nupG GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015212,GO:0015213,GO:0015214,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015506,GO:0015672,GO:0015858,GO:0015861,GO:0015862,GO:0015864,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072531,GO:0098655,GO:0098660,GO:0098662,GO:1901264,GO:1901505,GO:1901642,GO:1902600 ko:K03317,ko:K16323 ko00000,ko02000 2.A.41,2.A.41.1 Bacteria 1TRSK@1239,3FB6J@33958,4HBRZ@91061,COG1972@1,COG1972@2 NA|NA|NA F Nucleoside transporter KIAJIJGH_01598 334390.LAF_0673 1.2e-61 243.0 Lactobacillaceae Bacteria 1UHY6@1239,3FBS3@33958,4ISAK@91061,COG4932@1,COG4932@2 NA|NA|NA M domain protein KIAJIJGH_01599 1400520.LFAB_17405 2.9e-62 244.6 Lactobacillaceae Bacteria 1U65M@1239,3F74C@33958,4IFVG@91061,COG1846@1,COG1846@2 NA|NA|NA K helix_turn_helix multiple antibiotic resistance protein KIAJIJGH_01600 1400520.LFAB_17410 1.7e-78 299.7 Lactobacillaceae Bacteria 1VXP5@1239,3F5AT@33958,4HWZF@91061,COG3203@1,COG3203@2,COG4932@1,COG4932@2 NA|NA|NA M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane KIAJIJGH_01601 649639.Bcell_0202 1.3e-151 542.7 Bacillus 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Bacteria 1TSNX@1239,1ZQDR@1386,4HF9J@91061,COG0270@1,COG0270@2 NA|NA|NA H C-5 cytosine-specific DNA methylase KIAJIJGH_01602 334390.LAF_0042 3.4e-23 114.0 Lactobacillaceae ybhF_2 ko:K01990,ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TQKM@1239,3F3VV@33958,4HBUK@91061,COG1131@1,COG1131@2 NA|NA|NA V AAA domain, putative AbiEii toxin, Type IV TA system KIAJIJGH_01603 334390.LAF_0043 1.4e-93 349.0 Bacteria Bacteria COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator KIAJIJGH_01604 575594.ACOH01000026_gene64 7.4e-167 593.2 Lactobacillaceae guaC 1.1.1.205,1.7.1.7 ko:K00088,ko:K00364 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R01134,R08240 RC00143,RC00457,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 iSB619.SA_RS06660 Bacteria 1TNYF@1239,3F45K@33958,4HA55@91061,COG0516@1,COG0516@2 NA|NA|NA F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides KIAJIJGH_01605 334390.LAF_0044 6e-249 866.3 Lactobacillaceae purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQ4C@1239,3F3RQ@33958,4H9YT@91061,COG0104@1,COG0104@2 NA|NA|NA F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP KIAJIJGH_01606 334390.LAF_0785 1.4e-220 771.9 Lactobacillaceae iscS 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Bacteria 1TP21@1239,3F3RF@33958,4HA6H@91061,COG1104@1,COG1104@2 NA|NA|NA E Aminotransferase class V KIAJIJGH_01607 1410622.JNKY01000015_gene334 1.5e-15 89.4 unclassified Lachnospiraceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1V2P1@1239,24BRH@186801,27MZI@186928,COG1277@1,COG1277@2 NA|NA|NA S Psort location CytoplasmicMembrane, score KIAJIJGH_01608 1121914.AUDW01000024_gene105 1.1e-50 206.5 Bacillales incertae sedis Bacteria 1TSWT@1239,3WFJH@539002,4HGB5@91061,COG0745@1,COG0745@2 NA|NA|NA T Transcriptional regulatory protein, C terminal KIAJIJGH_01609 1121914.AUDW01000024_gene106 3.1e-62 245.7 Bacillales incertae sedis Bacteria 1V10X@1239,3WFND@539002,4HB4P@91061,COG0642@1,COG2205@2 NA|NA|NA T His Kinase A (phosphoacceptor) domain KIAJIJGH_01610 575594.ACOH01000002_gene1000 5.9e-11 72.8 Lactobacillaceae Bacteria 1V45R@1239,3F7P2@33958,4HQY8@91061,COG0716@1,COG0716@2 NA|NA|NA C Flavodoxin KIAJIJGH_01611 334390.LAF_0776 5.9e-202 709.9 Lactobacillaceae ribD GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 1.1.1.193,3.5.4.26 ko:K00082,ko:K01498,ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1624,iLJ478.TM1828 Bacteria 1TP4F@1239,3F4X5@33958,4HBNA@91061,COG0117@1,COG0117@2,COG1985@1,COG1985@2 NA|NA|NA H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate KIAJIJGH_01612 334390.LAF_0775 1.7e-105 388.7 Lactobacillaceae ribE GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9,3.5.4.25,4.1.99.12 ko:K00793,ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00066,R00425,R07281 RC00293,RC00958,RC00960,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS08950,iYO844.BSU23270 Bacteria 1V1EP@1239,3F6M0@33958,4HC7B@91061,COG0307@1,COG0307@2 NA|NA|NA H Riboflavin synthase KIAJIJGH_01613 334390.LAF_0774 9.2e-228 795.8 Lactobacillaceae ribBA GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 iHN637.CLJU_RS10830,iSB619.SA_RS08945 Bacteria 1TPH9@1239,3F4EB@33958,4H9PW@91061,COG0108@1,COG0108@2,COG0807@1,COG0807@2 NA|NA|NA H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate KIAJIJGH_01614 334390.LAF_0773 1.9e-80 305.1 Lactobacillaceae ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1825,iSB619.SA_RS08940,iSFV_1184.SFV_0380 Bacteria 1V1DA@1239,3F70X@33958,4HFRA@91061,COG0054@1,COG0054@2 NA|NA|NA H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin KIAJIJGH_01615 334390.LAF_0772 3.5e-79 300.8 Bacteria Bacteria COG1959@1,COG1959@2 NA|NA|NA K 2 iron, 2 sulfur cluster binding KIAJIJGH_01616 334390.LAF_0770 1.7e-267 928.3 Lactobacillaceae ko:K12410 ko00000,ko01000 Bacteria 1TQB7@1239,3F4Q7@33958,4HAQT@91061,COG0846@1,COG0846@2 NA|NA|NA K COG COG0846 NAD-dependent protein deacetylases, SIR2 family KIAJIJGH_01617 334390.LAF_0769 4.8e-221 773.5 Lactobacillaceae serA 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 Bacteria 1V410@1239,3F4JJ@33958,4H9PH@91061,COG0111@1,COG0111@2 NA|NA|NA EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family KIAJIJGH_01618 334390.LAF_0768 5.4e-203 713.4 Lactobacillaceae serC GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP6Y@1239,3F4IU@33958,4HATT@91061,COG1932@1,COG1932@2 NA|NA|NA E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine KIAJIJGH_01619 484018.BACPLE_02599 2.8e-82 312.0 Bacteroidaceae Bacteria 2FQ6I@200643,4AQAA@815,4NKHD@976,COG0667@1,COG0667@2 NA|NA|NA C aldo keto reductase KIAJIJGH_01620 484018.BACPLE_02599 7.5e-18 95.9 Bacteroidaceae Bacteria 2FQ6I@200643,4AQAA@815,4NKHD@976,COG0667@1,COG0667@2 NA|NA|NA C aldo keto reductase KIAJIJGH_01621 334390.LAF_0767 2.5e-112 411.4 Lactobacillaceae 3.1.3.73 ko:K02226 ko00860,ko01100,map00860,map01100 M00122 R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1V6ES@1239,3F5SD@33958,4HGZI@91061,COG0406@1,COG0406@2 NA|NA|NA G phosphoglycerate mutase KIAJIJGH_01622 525309.HMPREF0494_1864 3.3e-09 68.6 Lactobacillaceae Bacteria 1U78H@1239,29PZ6@1,30AXM@2,3F947@33958,4IH3D@91061 NA|NA|NA KIAJIJGH_01623 334390.LAF_0765 0.0 1197.2 Lactobacillaceae lepA ko:K03596 ko05134,map05134 ko00000,ko00001 Bacteria 1TP0G@1239,3F3Z1@33958,4HASA@91061,COG0481@1,COG0481@2 NA|NA|NA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner KIAJIJGH_01624 334390.LAF_0764 5.1e-201 706.8 Lactobacillaceae hisC 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TPUV@1239,3F466@33958,4HA1H@91061,COG0079@1,COG0079@2 NA|NA|NA E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily KIAJIJGH_01625 334390.LAF_0763 9.9e-52 209.1 Lactobacillaceae hisE GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31,5.3.1.16 ko:K01523,ko:K01814,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037,R04640 RC00002,RC00945,RC01055 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS14110,iYO844.BSU34860 Bacteria 1VB6S@1239,3F7V5@33958,4HKDY@91061,COG0140@1,COG0140@2 NA|NA|NA E phosphoribosyl-ATP diphosphatase activity KIAJIJGH_01626 334390.LAF_0762 2.9e-56 224.2 Lactobacillaceae hisI GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.5.4.25,3.6.1.31,5.3.1.16 ko:K01496,ko:K01497,ko:K01814,ko:K11755 ko00340,ko00740,ko00790,ko01100,ko01110,ko01230,ko02024,map00340,map00740,map00790,map01100,map01110,map01230,map02024 M00026,M00125 R00425,R04035,R04037,R04640 RC00002,RC00293,RC00945,RC01055,RC02504 ko00000,ko00001,ko00002,ko01000 iECNA114_1301.ECNA114_0880,iECW_1372.ECW_m2186,iEKO11_1354.EKO11_1768,iHN637.CLJU_RS05760,iSB619.SA_RS14110,iUMN146_1321.UM146_06665,iWFL_1372.ECW_m2186 Bacteria 1UYNA@1239,3F73W@33958,4HA9R@91061,COG0139@1,COG0139@2 NA|NA|NA E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP KIAJIJGH_01627 334390.LAF_0761 2.1e-140 505.0 Lactobacillaceae hisF GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 3.5.4.19,3.6.1.31 ko:K01663,ko:K02500,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037,R04558 RC00002,RC00010,RC01055,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 iECO111_1330.ECO111_2749,iEcolC_1368.EcolC_1617,iHN637.CLJU_RS05755,iLJ478.TM1036,iSB619.SA_RS14115,iYL1228.KPN_02481 Bacteria 1TP0W@1239,3F3XV@33958,4HAAM@91061,COG0107@1,COG0107@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit KIAJIJGH_01628 334390.LAF_0760 5.4e-130 470.3 Lactobacillaceae hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_0388 Bacteria 1V1IR@1239,3F5YT@33958,4HACP@91061,COG0106@1,COG0106@2 NA|NA|NA E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase KIAJIJGH_01629 334390.LAF_0759 1.2e-111 409.1 Lactobacillaceae hisH ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQT0@1239,3FBCF@33958,4HFXQ@91061,COG0118@1,COG0118@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR KIAJIJGH_01630 334390.LAF_0758 2.2e-102 378.3 Lactobacillaceae hisB GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,2.6.1.9,3.1.3.15,4.2.1.19 ko:K00013,ko:K00817,ko:K01089,ko:K01693 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R01158,R01163,R03012,R03013,R03243,R03457 RC00006,RC00017,RC00099,RC00242,RC00463,RC00888,RC00932 ko00000,ko00001,ko00002,ko01000,ko01007 iECO111_1330.ECO111_2746,iECS88_1305.ECS88_2121,iJN746.PP_0289,iLJ478.TM1039,iSB619.SA_RS14130,iUMNK88_1353.UMNK88_2570 Bacteria 1TRH7@1239,3F4TQ@33958,4HCFG@91061,COG0131@1,COG0131@2 NA|NA|NA E imidazoleglycerol-phosphate dehydratase KIAJIJGH_01631 334390.LAF_0757 6.8e-229 799.7 Lactobacillaceae hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,1.1.1.308 ko:K00013,ko:K15509 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPAW@1239,3F40P@33958,4H9XK@91061,COG0141@1,COG0141@2 NA|NA|NA E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine KIAJIJGH_01632 334390.LAF_0756 4.9e-108 397.1 Lactobacillaceae hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSVZ@1239,3F4WT@33958,4H9MH@91061,COG0040@1,COG0040@2 NA|NA|NA F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity KIAJIJGH_01633 334390.LAF_0755 2.1e-216 758.1 Lactobacillaceae hisZ 2.4.2.17,6.1.1.21 ko:K00765,ko:K01892,ko:K02502 ko00340,ko00970,ko01100,ko01110,ko01230,map00340,map00970,map01100,map01110,map01230 M00026,M00359,M00360 R01071,R03655 RC00055,RC00523,RC02819,RC03200 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPZZ@1239,3F4W1@33958,4HBBA@91061,COG3705@1,COG3705@2 NA|NA|NA E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine KIAJIJGH_01634 334390.LAF_0754 3.4e-168 597.4 Lactobacillaceae hisK 3.1.3.15 ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQQX@1239,3F4WG@33958,4H9P1@91061,COG1387@1,COG1387@2 NA|NA|NA E Histidinol phosphate phosphatase, HisJ KIAJIJGH_01635 334390.LAF_0761 8.5e-51 206.8 Lactobacillaceae hisF GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 3.5.4.19,3.6.1.31 ko:K01663,ko:K02500,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037,R04558 RC00002,RC00010,RC01055,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 iECO111_1330.ECO111_2749,iEcolC_1368.EcolC_1617,iHN637.CLJU_RS05755,iLJ478.TM1036,iSB619.SA_RS14115,iYL1228.KPN_02481 Bacteria 1TP0W@1239,3F3XV@33958,4HAAM@91061,COG0107@1,COG0107@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit KIAJIJGH_01636 334390.LAF_0761 1.3e-07 61.6 Lactobacillaceae hisF GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 3.5.4.19,3.6.1.31 ko:K01663,ko:K02500,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037,R04558 RC00002,RC00010,RC01055,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 iECO111_1330.ECO111_2749,iEcolC_1368.EcolC_1617,iHN637.CLJU_RS05755,iLJ478.TM1036,iSB619.SA_RS14115,iYL1228.KPN_02481 Bacteria 1TP0W@1239,3F3XV@33958,4HAAM@91061,COG0107@1,COG0107@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit KIAJIJGH_01637 334390.LAF_0753 2.4e-53 214.5 Lactobacillaceae hisH ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQT0@1239,3F5AD@33958,4HHNQ@91061,COG0118@1,COG0118@2 NA|NA|NA E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR KIAJIJGH_01638 334390.LAF_0752 1.1e-177 629.4 Lactobacillaceae dnaJ ko:K03686 ko00000,ko03029,ko03110 Bacteria 1TP00@1239,3F490@33958,4H9KA@91061,COG0484@1,COG0484@2 NA|NA|NA O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins KIAJIJGH_01639 334390.LAF_0751 0.0 1168.3 Lactobacillaceae dnaK GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065 ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 Bacteria 1TP1J@1239,3F48C@33958,4HA9S@91061,COG0443@1,COG0443@2 NA|NA|NA O Heat shock 70 kDa protein KIAJIJGH_01640 334390.LAF_0750 2.2e-57 228.8 Lactobacillaceae grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009628,GO:0009986,GO:0009987,GO:0009991,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030246,GO:0030247,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071496,GO:0071840,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 ko:K03687 ko00000,ko03029,ko03110 Bacteria 1V6G2@1239,3F4DY@33958,4HIRK@91061,COG0576@1,COG0576@2 NA|NA|NA O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ KIAJIJGH_01641 334390.LAF_0749 5.4e-192 676.8 Lactobacillaceae hrcA GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 ko:K03705 ko00000,ko03000 Bacteria 1TQP7@1239,3F3ST@33958,4HAX5@91061,COG1420@1,COG1420@2 NA|NA|NA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons KIAJIJGH_01642 334390.LAF_0748 2e-61 241.5 Lactobacillaceae Bacteria 1U6DW@1239,2A5X0@1,30UP0@2,3F7P8@33958,4IG5K@91061 NA|NA|NA KIAJIJGH_01643 1141106.CAIB01000160_gene1539 8.4e-16 90.9 Staphylococcaceae ko:K07727 ko00000,ko03000 Bacteria 1VKVP@1239,4H03P@90964,4HRJ4@91061,COG3655@1,COG3655@2 NA|NA|NA K Cro/C1-type HTH DNA-binding domain KIAJIJGH_01644 525318.HMPREF0497_2551 3.1e-101 375.2 Lactobacillaceae MA20_03535 1.1.1.399,1.1.1.95 ko:K00058,ko:K04496 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,ko04310,ko04330,ko05200,ko05220,map00260,map00680,map01100,map01120,map01130,map01200,map01230,map04310,map04330,map05200,map05220 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1TPCX@1239,3F4Z6@33958,4HASY@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family KIAJIJGH_01645 1423754.BALY01000018_gene358 2.9e-240 837.8 Lactobacillaceae treC GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005991,GO:0005993,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008788,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0015927,GO:0016052,GO:0016787,GO:0016798,GO:0033554,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046352,GO:0050896,GO:0051716,GO:0071704,GO:1901575 3.2.1.93 ko:K01226 ko00500,map00500 R00837,R06113 RC00049 ko00000,ko00001,ko01000 GH13 iECW_1372.ECW_m4600,iEKO11_1354.EKO11_4072,iEcE24377_1341.EcE24377A_4811,iEcSMS35_1347.EcSMS35_4720,iWFL_1372.ECW_m4600 Bacteria 1TP53@1239,3F41I@33958,4HA1G@91061,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain protein KIAJIJGH_01646 1133569.AHYZ01000079_gene1821 1.1e-71 276.6 Lactobacillaceae treR ko:K03486,ko:K03710 ko00000,ko03000 Bacteria 1TRF6@1239,3F62J@33958,4HDCX@91061,COG2188@1,COG2188@2 NA|NA|NA K UTRA KIAJIJGH_01647 1235801.C822_01379 3.4e-240 837.8 Lactobacillaceae treB ko:K02755,ko:K02756,ko:K02757,ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00271,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 Bacteria 1TP5X@1239,3F458@33958,4HA0I@91061,COG1263@1,COG1263@2,COG1264@1,COG1264@2,COG2190@1,COG2190@2 NA|NA|NA G phosphotransferase system KIAJIJGH_01648 334390.LAF_1025 2.4e-101 374.8 Bacteria Bacteria COG1595@1,COG1595@2 NA|NA|NA K DNA-templated transcription, initiation KIAJIJGH_01649 158787.BSCA_2075 4.8e-133 481.5 Bifidobacteriales manR ko:K02538 ko00000,ko03000 Bacteria 2HXN0@201174,4D049@85004,COG3711@1,COG3711@2 NA|NA|NA K PRD domain KIAJIJGH_01650 326426.Bbr_1388 1.9e-18 99.0 Bifidobacteriales Bacteria 2BIQA@1,2GTDU@201174,32CXN@2,4D1IN@85004 NA|NA|NA H Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 KIAJIJGH_01651 1133569.AHYZ01000075_gene96 2.2e-52 211.8 Lactobacillaceae 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 Bacteria 1V5TG@1239,3F7H8@33958,4HND7@91061,COG1762@1,COG1762@2 NA|NA|NA G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 KIAJIJGH_01652 326426.Bbr_1386 3.8e-40 170.6 Bifidobacteriales fruA 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 Bacteria 2IPEN@201174,4D113@85004,COG1445@1,COG1445@2 NA|NA|NA G PTS system, Lactose/Cellobiose specific IIB subunit KIAJIJGH_01653 218140.BPSY_1372 1.3e-127 463.0 Bifidobacteriales ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.2.1 Bacteria 2GJU4@201174,4CZ60@85004,COG1299@1,COG1299@2 NA|NA|NA G Phosphotransferase System KIAJIJGH_01654 1147128.BAST_0023 1.5e-108 399.1 Bifidobacteriales alsE GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019313,GO:0019314,GO:0019316,GO:0019318,GO:0019320,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0034700,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046367,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783,ko:K17195 ko00030,ko00040,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529,R09031 RC00540,RC03111 ko00000,ko00001,ko00002,ko01000 iEcSMS35_1347.EcSMS35_4551 Bacteria 2IC1U@201174,4CZWV@85004,COG0036@1,COG0036@2 NA|NA|NA G Ribulose-phosphate 3 epimerase family KIAJIJGH_01656 334390.LAF_1830 0.0 1201.4 Lactobacillaceae thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP78@1239,3F3TC@33958,4HABZ@91061,COG0441@1,COG0441@2 NA|NA|NA J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) KIAJIJGH_01657 334390.LAF_1831 1.2e-69 269.6 Lactobacillaceae ko:K02238 M00429 ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 Bacteria 1V8AM@1239,3F813@33958,4IPMQ@91061,COG1525@1,COG1525@2 NA|NA|NA L nuclease KIAJIJGH_01658 334390.LAF_1832 3.1e-116 424.5 Lactobacillaceae ko:K15051 ko00000 Bacteria 1TR37@1239,3F4MB@33958,4HHHQ@91061,COG2169@1,COG2169@2 NA|NA|NA F DNA/RNA non-specific endonuclease KIAJIJGH_01659 349123.Lreu23DRAFT_5062 2.4e-130 471.9 Lactobacillaceae Bacteria 1TWVR@1239,3F5JW@33958,4HCM1@91061,COG2826@1,COG2826@2 NA|NA|NA L PFAM Integrase catalytic region KIAJIJGH_01660 334390.LAF_1356 1.3e-224 785.4 Lactobacillaceae proA GO:0003674,GO:0003824,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 iB21_1397.B21_00243,iECBD_1354.ECBD_3376,iECB_1328.ECB_00240,iECD_1391.ECD_00240,iLJ478.TM0293,iYL1228.KPN_00280,iYO844.BSU13130 Bacteria 1TQ9V@1239,3F3W7@33958,4HB7B@91061,COG0014@1,COG0014@2 NA|NA|NA E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate KIAJIJGH_01661 334390.LAF_1357 3.7e-140 504.2 Lactobacillaceae proB GO:0003674,GO:0003824,GO:0004349,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016772,GO:0016774,GO:0016903,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPG6@1239,3F4E1@33958,4HA9B@91061,COG0263@1,COG0263@2 NA|NA|NA F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate KIAJIJGH_01662 334390.LAF_1358 8.6e-210 736.1 Lactobacillaceae metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPCV@1239,3F3T0@33958,4HB33@91061,COG0192@1,COG0192@2 NA|NA|NA H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme KIAJIJGH_01663 575594.ACOH01000003_gene931 5e-51 208.0 Lactobacillaceae Bacteria 1U53R@1239,2DKHQ@1,309HG@2,3F4DM@33958,4IEV1@91061 NA|NA|NA KIAJIJGH_01664 334390.LAF_1360 3.8e-96 357.5 Lactobacillaceae tag 3.2.2.20 ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Bacteria 1UYWG@1239,3F5KA@33958,4HGWW@91061,COG2818@1,COG2818@2 NA|NA|NA L glycosylase KIAJIJGH_01665 334390.LAF_1361 3.2e-251 874.0 Lactobacillaceae Bacteria 1TS0Y@1239,3F4GE@33958,4HEMR@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily KIAJIJGH_01666 334390.LAF_1362 7.4e-85 319.7 Lactobacillaceae perR GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 ko:K03711,ko:K09825 ko00000,ko03000 Bacteria 1V400@1239,3F67J@33958,4HHF8@91061,COG0735@1,COG0735@2 NA|NA|NA P Belongs to the Fur family KIAJIJGH_01667 334390.LAF_1363 5e-246 856.7 Lactobacillaceae cycA GO:0001761,GO:0001762,GO:0003333,GO:0003674,GO:0005215,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015180,GO:0015187,GO:0015238,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015808,GO:0015816,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0022858,GO:0022889,GO:0032328,GO:0032329,GO:0034220,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0042940,GO:0042941,GO:0042942,GO:0042943,GO:0042944,GO:0042945,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 ko:K03293,ko:K11737 ko00000,ko02000 2.A.3.1,2.A.3.1.7 iECO111_1330.ECO111_5093,iECO26_1355.ECO26_5376,iEcHS_1320.EcHS_A4458,iSbBS512_1146.SbBS512_E4749,iYL1228.KPN_04601 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease KIAJIJGH_01668 334390.LAF_1364 4e-22 109.8 Lactobacillaceae Bacteria 1U6S6@1239,29PMB@1,30AJH@2,3F8E9@33958,4IGJQ@91061 NA|NA|NA KIAJIJGH_01672 334390.LAF_1368 8.6e-111 406.8 Lactobacillaceae Bacteria 1U5TP@1239,3F6HI@33958,4IFHQ@91061,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator, TetR family KIAJIJGH_01673 334390.LAF_1369 2e-76 291.6 Lactobacillaceae hsp ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Bacteria 1VG0E@1239,3F7DR@33958,4HPDH@91061,COG0071@1,COG0071@2 NA|NA|NA O Belongs to the small heat shock protein (HSP20) family KIAJIJGH_01674 334390.LAF_1370 2.8e-85 321.2 Lactobacillaceae ykhA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 3.1.2.20 ko:K01073 ko00000,ko01000 Bacteria 1V3S2@1239,3F6A3@33958,4HJ0Z@91061,COG1607@1,COG1607@2 NA|NA|NA I Thioesterase superfamily KIAJIJGH_01675 334390.LAF_1371 9.4e-62 243.8 Lactobacillaceae lytE Bacteria 1V773@1239,3F3JQ@33958,4HIJG@91061,COG1388@1,COG1388@2 NA|NA|NA M LysM domain protein KIAJIJGH_01676 334390.LAF_1372 2.9e-77 294.7 Lactobacillaceae adh 1.1.1.1,1.1.1.14 ko:K00001,ko:K00008 ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 M00014 R00623,R00754,R00875,R01896,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00085,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPIW@1239,3F5ST@33958,4HB2G@91061,COG1063@1,COG1063@2 NA|NA|NA C Zinc-binding dehydrogenase KIAJIJGH_01677 575594.ACOH01000003_gene684 4.8e-258 897.1 Lactobacillaceae tkt 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPIB@1239,3F4IJ@33958,4HADA@91061,COG0021@1,COG0021@2 NA|NA|NA H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate KIAJIJGH_01678 60520.HR47_10960 3.7e-193 681.0 Lactobacillaceae ulaA 2.7.1.194 ko:K02822,ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 Bacteria 1TQK5@1239,3F4Y4@33958,4HBAD@91061,COG3037@1,COG3037@2 NA|NA|NA S PTS system sugar-specific permease component KIAJIJGH_01679 575594.ACOH01000003_gene686 6.1e-40 169.9 Lactobacillaceae ulaB 2.7.1.194 ko:K02822,ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 Bacteria 1VBT2@1239,3F7EB@33958,4HMYC@91061,COG3414@1,COG3414@2 NA|NA|NA G Phosphotransferase system galactitol-specific IIB component KIAJIJGH_01680 575594.ACOH01000003_gene687 2.3e-43 181.8 Bacilli 2.7.1.194,2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02821 ko00051,ko00053,ko01100,ko01120,ko02060,map00051,map00053,map01100,map01120,map02060 M00273,M00283,M00550 R03232,R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.7.1 Bacteria 1V892@1239,4IQ7Y@91061,COG1762@1,COG1762@2 NA|NA|NA G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 KIAJIJGH_01681 1545701.LACWKB10_1448 6.2e-131 474.9 Lactobacillaceae 2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K03483 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1 Bacteria 1TQT1@1239,3F5NN@33958,4H9N4@91061,COG1762@1,COG1762@2,COG3711@1,COG3711@2 NA|NA|NA G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 KIAJIJGH_01682 334390.LAF_0745 2.7e-239 834.3 Lactobacillaceae cycA GO:0001761,GO:0001762,GO:0003333,GO:0003674,GO:0005215,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015180,GO:0015187,GO:0015238,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015808,GO:0015816,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0022858,GO:0022889,GO:0032328,GO:0032329,GO:0034220,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0042940,GO:0042941,GO:0042942,GO:0042943,GO:0042944,GO:0042945,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 ko:K03293,ko:K11737 ko00000,ko02000 2.A.3.1,2.A.3.1.7 iECO111_1330.ECO111_5093,iECO26_1355.ECO26_5376,iEcHS_1320.EcHS_A4458,iSbBS512_1146.SbBS512_E4749,iYL1228.KPN_04601 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease KIAJIJGH_01683 334390.LAF_0744 1.7e-254 884.8 Lactobacillaceae dsdA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008721,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009636,GO:0009987,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016840,GO:0016841,GO:0017144,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0033554,GO:0036088,GO:0036094,GO:0042221,GO:0042737,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046416,GO:0048037,GO:0050662,GO:0050896,GO:0051410,GO:0051716,GO:0070178,GO:0070279,GO:0071704,GO:0097159,GO:0098754,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901698 4.3.1.18 ko:K01753 ko00260,map00260 R00221 RC02600 ko00000,ko00001,ko01000 iECED1_1282.ECED1_2813,iLF82_1304.LF82_0525,iNRG857_1313.NRG857_11890 Bacteria 1TPAH@1239,3F4S1@33958,4HANC@91061,COG3048@1,COG3048@2 NA|NA|NA E Belongs to the serine threonine dehydratase family. DsdA subfamily KIAJIJGH_01684 1140001.I571_00597 1.1e-16 93.2 Enterococcaceae Bacteria 1V43K@1239,4B2MB@81852,4HH01@91061,COG1733@1,COG1733@2 NA|NA|NA K HxlR-like helix-turn-helix KIAJIJGH_01685 1224318.DT73_10535 5.6e-31 141.0 Gammaproteobacteria Bacteria 1MXNX@1224,1RQVH@1236,COG1028@1,COG1028@2 NA|NA|NA IQ Dehydrogenase KIAJIJGH_01686 1423806.JCM15457_255 1.2e-89 337.0 Lactobacillaceae nagZ 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP63@1239,3F4B7@33958,4HBDB@91061,COG1472@1,COG1472@2 NA|NA|NA G Glycosyl hydrolase family 3 N terminal domain KIAJIJGH_01687 1423767.BALU01000002_gene1764 1.3e-09 68.9 Lactobacillaceae nagZ 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP63@1239,3F4B7@33958,4HBDB@91061,COG1472@1,COG1472@2 NA|NA|NA G Glycosyl hydrolase family 3 N terminal domain KIAJIJGH_01688 334390.LAF_0122 3.1e-236 824.3 Lactobacillaceae Bacteria 1UYJN@1239,3FBEE@33958,4HF8I@91061,COG4640@1,COG4640@2 NA|NA|NA S response to antibiotic KIAJIJGH_01689 334390.LAF_0121 4.8e-169 600.5 Bacteria hrpQ 4.6.1.1 ko:K01768,ko:K03220,ko:K10914 ko00230,ko02020,ko02024,ko02025,ko02026,ko04113,ko04213,ko05111,map00230,map02020,map02024,map02025,map02026,map04113,map04213,map05111 M00332,M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko02044,ko03000 3.A.6.1 Bacteria COG1716@1,COG1716@2 NA|NA|NA T histone H2A K63-linked ubiquitination KIAJIJGH_01690 334390.LAF_0120 1.2e-254 885.2 Lactobacillaceae purB GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 iLJ478.TM1095 Bacteria 1TPMM@1239,3F48P@33958,4HACW@91061,COG0015@1,COG0015@2 NA|NA|NA F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily KIAJIJGH_01691 334390.LAF_0119 2.9e-215 754.2 Lactobacillaceae purK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQCD@1239,3F3YV@33958,4H9M5@91061,COG0026@1,COG0026@2 NA|NA|NA F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) KIAJIJGH_01692 334390.LAF_0118 5.3e-81 307.0 Lactobacillaceae purE GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 iETEC_1333.ETEC_0575,iJN746.PP_5336,iPC815.YPO3076,iUTI89_1310.UTI89_C0551 Bacteria 1V1MV@1239,3F6P0@33958,4HFR7@91061,COG0041@1,COG0041@2 NA|NA|NA F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) KIAJIJGH_01693 334390.LAF_0117 0.0 1092.0 Lactobacillaceae fhs GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP6N@1239,3F3U6@33958,4HA2X@91061,COG2759@1,COG2759@2 NA|NA|NA F Belongs to the formate--tetrahydrofolate ligase family KIAJIJGH_01694 334390.LAF_0116 1.1e-163 582.8 Lactobacillaceae Bacteria 1TSBK@1239,3F46E@33958,4HBYJ@91061,COG0628@1,COG0628@2 NA|NA|NA K AI-2E family transporter KIAJIJGH_01695 1400520.LFAB_06315 8.1e-14 82.8 Lactobacillaceae Bacteria 1VFA9@1239,3F6J9@33958,4IFIV@91061,COG1309@1,COG1309@2 NA|NA|NA K Bacterial regulatory proteins, tetR family KIAJIJGH_01696 1123304.AQYA01000021_gene54 1e-26 125.9 Firmicutes Bacteria 1VFA9@1239,COG1309@1,COG1309@2 NA|NA|NA K transcriptional regulator KIAJIJGH_01697 334390.LAF_0115 9.8e-230 802.4 Lactobacillaceae cfa 2.1.1.317,2.1.1.79 ko:K00574,ko:K20238 ko00000,ko01000 Bacteria 1TSG4@1239,3F3PA@33958,4HDKI@91061,COG2230@1,COG2230@2 NA|NA|NA M cyclopropane-fatty-acyl-phospholipid synthase KIAJIJGH_01698 334390.LAF_0114 3.6e-28 130.2 Lactobacillaceae ydeN ko:K07002 ko00000 Bacteria 1V6R4@1239,3FBQF@33958,4HVF4@91061,COG3545@1,COG3545@2 NA|NA|NA S Serine hydrolase KIAJIJGH_01699 334390.LAF_0112 2e-39 167.9 Lactobacillaceae Bacteria 1UTIV@1239,3F8FJ@33958,4IGKK@91061,COG2002@1,COG2002@2 NA|NA|NA K prlF antitoxin for toxin YhaV_toxin KIAJIJGH_01700 334390.LAF_0111 1.2e-60 239.2 Lactobacillaceae azlD Bacteria 1UF1S@1239,3F7GD@33958,4HQ7J@91061,COG4392@1,COG4392@2 NA|NA|NA S branched-chain amino acid KIAJIJGH_01701 334390.LAF_0110 2.6e-139 501.5 Lactobacillaceae azlC Bacteria 1TP8P@1239,3FB4H@33958,4HN4R@91061,COG1296@1,COG1296@2 NA|NA|NA E AzlC protein KIAJIJGH_01702 334390.LAF_0109 8e-126 456.4 Lactobacillaceae dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 1TQN0@1239,3F43S@33958,4HBD4@91061,COG1686@1,COG1686@2 NA|NA|NA M Belongs to the peptidase S11 family KIAJIJGH_01703 334390.LAF_0109 4e-161 574.3 Lactobacillaceae dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Bacteria 1TQN0@1239,3F43S@33958,4HBD4@91061,COG1686@1,COG1686@2 NA|NA|NA M Belongs to the peptidase S11 family KIAJIJGH_01704 334390.LAF_0108 6.7e-66 256.5 Lactobacillaceae hpk31 2.7.13.3 ko:K07636 ko02020,map02020 M00434 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TPB6@1239,3F479@33958,4HARU@91061,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase KIAJIJGH_01705 334390.LAF_1689 2.9e-165 587.8 Lactobacillaceae rbsK 2.7.1.15 ko:K00852 ko00030,map00030 R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TQRC@1239,3F3S5@33958,4HA87@91061,COG0524@1,COG0524@2 NA|NA|NA H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway KIAJIJGH_01706 334390.LAF_1688 1.1e-161 575.9 Lactobacillaceae glxR 1.1.1.31,1.1.1.60 ko:K00020,ko:K00042 ko00280,ko00630,ko01100,map00280,map00630,map01100 R01745,R01747,R05066 RC00099 ko00000,ko00001,ko01000 iJN678.mmsB Bacteria 1TR4F@1239,3F3XC@33958,4H9MA@91061,COG2084@1,COG2084@2 NA|NA|NA I Dehydrogenase KIAJIJGH_01707 334390.LAF_1687 3e-184 651.0 Lactobacillaceae fruR3 ko:K02529,ko:K03484 ko00000,ko03000 Bacteria 1TQ7K@1239,3F4JE@33958,4H9V1@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator, LacI family KIAJIJGH_01708 334390.LAF_0087 7.2e-141 506.5 Lactobacillaceae ywqE 3.1.3.48 ko:K01104 ko00000,ko01000 Bacteria 1TQ1T@1239,3F3RT@33958,4HDZR@91061,COG4464@1,COG4464@2 NA|NA|NA GM PHP domain protein KIAJIJGH_01709 334390.LAF_0086 2.7e-116 424.9 Lactobacillaceae ywqD 2.7.10.1 ko:K08252,ko:K16554 ko05111,map05111 ko00000,ko00001,ko01000,ko02000 8.A.3.1 Bacteria 1TS4R@1239,3F4BM@33958,4HCEN@91061,COG0489@1,COG0489@2 NA|NA|NA D Capsular exopolysaccharide family KIAJIJGH_01710 334390.LAF_0085 3.6e-65 254.2 Lactobacillaceae epsB Bacteria 1UZCR@1239,3F4M5@33958,4HE26@91061,COG3944@1,COG3944@2 NA|NA|NA M biosynthesis protein KIAJIJGH_01711 334390.LAF_1744 3.9e-187 660.6 Lactobacillaceae ko:K02525 ko00000,ko03000 Bacteria 1TQSY@1239,3F51M@33958,4HAJI@91061,COG1609@1,COG1609@2 NA|NA|NA K helix_turn _helix lactose operon repressor KIAJIJGH_01712 334390.LAF_0014 6.3e-50 203.0 Lactobacillaceae Bacteria 1U690@1239,29P85@1,30A67@2,3F7C2@33958,4IG05@91061 NA|NA|NA KIAJIJGH_01713 334390.LAF_0013 2.2e-205 721.5 Lactobacillaceae lmrP ko:K03305,ko:K08152 ko00000,ko02000 2.A.1.2,2.A.17 Bacteria 1UHXR@1239,3FBRN@33958,4ISA6@91061,COG3104@1,COG3104@2 NA|NA|NA E Major Facilitator Superfamily KIAJIJGH_01714 334390.LAF_0012 6.3e-244 849.7 Lactobacillaceae dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Bacteria 1TPCT@1239,3F4MW@33958,4H9Y8@91061,COG0305@1,COG0305@2 NA|NA|NA L Participates in initiation and elongation during chromosome replication KIAJIJGH_01715 334390.LAF_0011 1.2e-74 285.8 Lactobacillaceae rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02939 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6QG@1239,3F68P@33958,4HIKJ@91061,COG0359@1,COG0359@2 NA|NA|NA J Binds to the 23S rRNA KIAJIJGH_01716 334390.LAF_0010 0.0 1308.9 Lactobacillaceae yybT Bacteria 1TPGP@1239,3F3TY@33958,4HBVH@91061,COG3887@1,COG3887@2 NA|NA|NA T signaling protein consisting of a modified GGDEF domain and a DHH domain KIAJIJGH_01717 1203076.CAKF01000020_gene1592 2.1e-35 154.5 Lactobacillaceae rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02963,ko:K03111,ko:K15125 ko03010,ko03030,ko03430,ko03440,ko05133,map03010,map03030,map03430,map03440,map05133 M00178 br01610,ko00000,ko00001,ko00002,ko00536,ko03011,ko03029,ko03032,ko03400 Bacteria 1V9XS@1239,3F7CY@33958,4HKCC@91061,COG0238@1,COG0238@2 NA|NA|NA J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit KIAJIJGH_01718 334390.LAF_0008 2.1e-89 335.5 Lactobacillaceae ssb ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Bacteria 1V3WT@1239,3F66N@33958,4HH8I@91061,COG0629@1,COG0629@2 NA|NA|NA L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism KIAJIJGH_01719 334390.LAF_0007 3.6e-48 197.2 Lactobacillaceae rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 ko:K02990 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1VA18@1239,3F6ZY@33958,4HKHD@91061,COG0360@1,COG0360@2 NA|NA|NA J Binds together with S18 to 16S ribosomal RNA KIAJIJGH_01720 334390.LAF_1787 1.3e-49 202.2 Lactobacillaceae crtB 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 Bacteria 1TQHF@1239,3F8JK@33958,4HA1A@91061,COG1562@1,COG1562@2 NA|NA|NA I Squalene/phytoene synthase KIAJIJGH_01721 334390.LAF_1785 1.7e-161 575.5 Lactobacillaceae hrtB ko:K02004 M00258 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TWFZ@1239,3F3K5@33958,4H9RQ@91061,COG0577@1,COG0577@2 NA|NA|NA V ABC transporter permease KIAJIJGH_01722 1291743.LOSG293_360120 4.5e-115 420.6 Lactobacillaceae devA 3.6.3.25 ko:K02003,ko:K06020,ko:K09810 ko02010,map02010 M00255,M00258 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.125 Bacteria 1TQP5@1239,3F4RP@33958,4HBXK@91061,COG1136@1,COG1136@2 NA|NA|NA V ABC transporter, ATP-binding protein KIAJIJGH_01723 1291743.LOSG293_360110 2.6e-109 401.4 Lactobacillaceae Bacteria 1TQAX@1239,3F429@33958,4HCFF@91061,COG1961@1,COG1961@2 NA|NA|NA L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed KIAJIJGH_01724 568703.LGG_00020 3.4e-191 674.1 Lactobacillaceae Bacteria 1TRSF@1239,3F3YG@33958,4HADR@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family KIAJIJGH_01725 935836.JAEL01000040_gene4773 1.2e-53 215.7 Bacillus ko:K21903 ko00000,ko03000 Bacteria 1VFNB@1239,1ZQGP@1386,4HQ6G@91061,COG0640@1,COG0640@2 NA|NA|NA K helix_turn_helix, Arsenical Resistance Operon Repressor KIAJIJGH_01726 1384049.CD29_19250 0.0 1243.8 Lysinibacillus cadA 3.6.3.3,3.6.3.5 ko:K01534 ko00000,ko01000 3.A.3.6 Bacteria 1TQ07@1239,3IWQZ@400634,4H9SP@91061,COG2217@1,COG2217@2 NA|NA|NA P Cadmium transporter KIAJIJGH_01727 334390.LAF_0131 1e-292 1011.9 Lactobacillaceae purH GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 iJN678.purH Bacteria 1TPQ5@1239,3F4FD@33958,4H9YY@91061,COG0138@1,COG0138@2 NA|NA|NA F Bifunctional purine biosynthesis protein PurH KIAJIJGH_01728 334390.LAF_0130 8.7e-107 392.9 Lactobacillaceae purN 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 Bacteria 1V3RJ@1239,3F3UN@33958,4HGY5@91061,COG0299@1,COG0299@2 NA|NA|NA F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate KIAJIJGH_01729 334390.LAF_0129 1.6e-196 691.8 Lactobacillaceae purM GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 ko:K01933,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04208 RC00090,RC00166,RC01100 ko00000,ko00001,ko00002,ko01000 iAF987.Gmet_1844,iECSF_1327.ECSF_2340 Bacteria 1TP9J@1239,3F4RT@33958,4HABW@91061,COG0150@1,COG0150@2 NA|NA|NA F Phosphoribosylformylglycinamidine cyclo-ligase KIAJIJGH_01730 334390.LAF_0128 8.1e-38 162.5 Lactobacillaceae purF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 iSB619.SA_RS05225 Bacteria 1TPH3@1239,3F3U7@33958,4HAXU@91061,COG0034@1,COG0034@2 NA|NA|NA F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine KIAJIJGH_01731 334390.LAF_0128 8.6e-218 762.7 Lactobacillaceae purF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 iSB619.SA_RS05225 Bacteria 1TPH3@1239,3F3U7@33958,4HAXU@91061,COG0034@1,COG0034@2 NA|NA|NA F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine KIAJIJGH_01732 334390.LAF_0127 0.0 1469.5 Lactobacillaceae purL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPAS@1239,3F4IQ@33958,4HB3N@91061,COG0046@1,COG0046@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL KIAJIJGH_01733 334390.LAF_0126 1.6e-128 465.3 Lactobacillaceae purQ GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP1B@1239,3F48D@33958,4HAKZ@91061,COG0047@1,COG0047@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL KIAJIJGH_01734 334390.LAF_0125 3e-37 160.6 Lactobacillaceae purS 6.3.2.6,6.3.5.3 ko:K01923,ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463,R04591 RC00010,RC00064,RC00162,RC01160 ko00000,ko00001,ko00002,ko01000 iYO844.BSU06460 Bacteria 1VEH1@1239,3F81F@33958,4HP0E@91061,COG1828@1,COG1828@2 NA|NA|NA F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL KIAJIJGH_01735 334390.LAF_0124 9.5e-129 466.1 Lactobacillaceae purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016881,GO:0044424,GO:0044444,GO:0044464 4.1.1.21,4.3.2.2,6.3.2.6 ko:K01587,ko:K01756,ko:K01923 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04209,R04559,R04591 RC00064,RC00162,RC00379,RC00444,RC00445,RC00590 ko00000,ko00001,ko00002,ko01000 iAF1260.b2476,iB21_1397.B21_02330,iBWG_1329.BWG_2240,iE2348C_1286.E2348C_2713,iEC042_1314.EC042_2677,iEC55989_1330.EC55989_2759,iECABU_c1320.ECABU_c27880,iECBD_1354.ECBD_1213,iECB_1328.ECB_02368,iECDH10B_1368.ECDH10B_2642,iECDH1ME8569_1439.ECDH1ME8569_2402,iECDH1ME8569_1439.EcDH1_1193,iECD_1391.ECD_02368,iECED1_1282.ECED1_2911,iECH74115_1262.ECH74115_3698,iECIAI1_1343.ECIAI1_2527,iECNA114_1301.ECNA114_2561,iECO103_1326.ECO103_2988,iECO111_1330.ECO111_3199,iECO26_1355.ECO26_3522,iECOK1_1307.ECOK1_2784,iECP_1309.ECP_2490,iECS88_1305.ECS88_2658,iECSE_1348.ECSE_2760,iECSF_1327.ECSF_2329,iECSP_1301.ECSP_3415,iECUMN_1333.ECUMN_2789,iECW_1372.ECW_m2698,iECs_1301.ECs3338,iEKO11_1354.EKO11_1259,iETEC_1333.ETEC_2581,iEcDH1_1363.EcDH1_1193,iEcE24377_1341.EcE24377A_2757,iEcHS_1320.EcHS_A2607,iEcSMS35_1347.EcSMS35_2623,iEcolC_1368.EcolC_1200,iG2583_1286.G2583_2999,iJN746.PP_1240,iJO1366.b2476,iJR904.b2476,iLF82_1304.LF82_1775,iNRG857_1313.NRG857_12360,iSFV_1184.SFV_2521,iSF_1195.SF2519,iSFxv_1172.SFxv_2773,iS_1188.S2669,iSbBS512_1146.SbBS512_E2848,iUMNK88_1353.UMNK88_3071,iWFL_1372.ECW_m2698,iY75_1357.Y75_RS12925,iYL1228.KPN_02810,iZ_1308.Z3735 Bacteria 1TP11@1239,3F44Z@33958,4H9U8@91061,COG0152@1,COG0152@2 NA|NA|NA F Belongs to the SAICAR synthetase family KIAJIJGH_01736 334390.LAF_1761 2.7e-274 950.7 Lactobacillaceae gnd GO:0003674,GO:0003824,GO:0004616,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019520,GO:0019521,GO:0019637,GO:0019682,GO:0019693,GO:0019752,GO:0032787,GO:0034641,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046176,GO:0046177,GO:0046395,GO:0046483,GO:0046496,GO:0046983,GO:0051156,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072329,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 iECS88_1305.ECS88_2128,iECW_1372.ECW_m2189,iEKO11_1354.EKO11_1765,iPC815.YPO1541,iWFL_1372.ECW_m2189 Bacteria 1TP4I@1239,3F3S8@33958,4H9NC@91061,COG0362@1,COG0362@2 NA|NA|NA H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH KIAJIJGH_01737 334390.LAF_1760 7.5e-288 995.7 Lactobacillaceae zwf GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 iIT341.HP1101 Bacteria 1TPYF@1239,3F48G@33958,4HA73@91061,COG0364@1,COG0364@2 NA|NA|NA G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone KIAJIJGH_01738 334390.LAF_1759 2.5e-206 724.5 Lactobacillaceae yeaN GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944 ko:K03449 ko00000,ko02000 2.A.1.17 Bacteria 1TP9R@1239,3F52B@33958,4H9YZ@91061,COG2807@1,COG2807@2 NA|NA|NA P Transporter, major facilitator family protein KIAJIJGH_01739 334390.LAF_1758 3.2e-74 284.3 Lactobacillaceae ko:K04750 ko00000 Bacteria 1V6QS@1239,3F6RM@33958,4HK80@91061,COG2764@1,COG2764@2 NA|NA|NA S 3-demethylubiquinone-9 3-methyltransferase KIAJIJGH_01740 334390.LAF_1757 2.4e-83 314.7 Lactobacillaceae nrdI ko:K03647 ko00000 Bacteria 1VWJA@1239,3FBB8@33958,4HW5I@91061,COG1780@1,COG1780@2 NA|NA|NA F Belongs to the NrdI family KIAJIJGH_01741 334390.LAF_1756 6.2e-252 876.3 Lactobacillaceae yhdP ko:K03699,ko:K06189 ko00000,ko02000,ko02042 9.A.40.1.2 Bacteria 1TPN0@1239,3F3TX@33958,4H9SB@91061,COG1253@1,COG1253@2 NA|NA|NA S Transporter associated domain KIAJIJGH_01742 334390.LAF_1755 3e-90 337.8 Lactobacillaceae Bacteria 1U673@1239,3F78A@33958,4IFXN@91061,COG0702@1,COG0702@2 NA|NA|NA GM epimerase KIAJIJGH_01743 334390.LAF_1754 1.3e-85 322.4 Lactobacillaceae M1-874 ko:K13638,ko:K13640 ko00000,ko03000 Bacteria 1V7Z4@1239,3FBF9@33958,4HJXK@91061,COG0789@1,COG0789@2 NA|NA|NA K Domain of unknown function (DUF1836) KIAJIJGH_01744 334390.LAF_1753 3.4e-157 560.8 Lactobacillaceae 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 GH20 Bacteria 1VSC9@1239,3F4RS@33958,4HUQI@91061,COG1082@1,COG1082@2 NA|NA|NA G Xylose isomerase domain protein TIM barrel KIAJIJGH_01745 334390.LAF_1752 1.2e-263 915.2 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase KIAJIJGH_01746 334390.LAF_1751 3.2e-130 471.1 Lactobacillaceae Bacteria 1V5G2@1239,31PIN@2,3F6X9@33958,4HIRV@91061,arCOG05209@1 NA|NA|NA KIAJIJGH_01747 334390.LAF_1750 7.1e-89 333.2 Lactobacillaceae ybaK ko:K03976 ko00000,ko01000,ko03016 Bacteria 1V6JF@1239,3FC62@33958,4HHFK@91061,COG2606@1,COG2606@2 NA|NA|NA J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily KIAJIJGH_01748 334390.LAF_1749 7e-130 469.9 Lactobacillaceae gntR ko:K03710 ko00000,ko03000 Bacteria 1TTCD@1239,3F4DA@33958,4HEXQ@91061,COG2188@1,COG2188@2 NA|NA|NA K UbiC transcription regulator-associated domain protein KIAJIJGH_01749 334390.LAF_1661 4.3e-92 344.0 Lactobacillaceae Bacteria 1VEM5@1239,3F66Z@33958,4HQRV@91061,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator (TetR family) KIAJIJGH_01750 334390.LAF_1660 5.5e-204 718.0 Lactobacillaceae ko:K01421 ko00000 Bacteria 1TQ15@1239,3F3Y3@33958,4H9T9@91061,COG1511@1,COG1511@2 NA|NA|NA V domain protein KIAJIJGH_01751 334390.LAF_1658 2e-80 305.1 Lactobacillaceae Bacteria 1U5C6@1239,3F5HT@33958,4IF3D@91061,COG0454@1,COG0456@2 NA|NA|NA K FR47-like protein KIAJIJGH_01752 334390.LAF_1660 3e-14 83.6 Lactobacillaceae ko:K01421 ko00000 Bacteria 1TQ15@1239,3F3Y3@33958,4H9T9@91061,COG1511@1,COG1511@2 NA|NA|NA V domain protein KIAJIJGH_01753 575605.ACQN01000025_gene913 3e-79 302.0 Lactobacillaceae Bacteria 1VR8Q@1239,2F08C@1,33TBR@2,3F6XD@33958,4HTKM@91061 NA|NA|NA KIAJIJGH_01755 575606.HMPREF0525_01309 2.5e-186 658.3 Lactobacillaceae ydaM Bacteria 1TRCI@1239,3FC1R@33958,4HAAK@91061,COG1215@1,COG1215@2 NA|NA|NA M Glycosyl transferase family group 2 KIAJIJGH_01756 575605.ACQN01000025_gene915 1.1e-121 443.4 Lactobacillaceae Bacteria 1VTKQ@1239,3FC1V@33958,4HTYV@91061,COG3405@1,COG3405@2 NA|NA|NA G Glycosyl hydrolases family 8 KIAJIJGH_01757 327277.JHAL01000001_gene1534 1.4e-142 512.7 Bifidobacteriales mnaA 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 Bacteria 2GJWS@201174,4D22I@85004,COG0381@1,COG0381@2 NA|NA|NA M UDP-N-acetylglucosamine 2-epimerase KIAJIJGH_01758 557436.Lreu_1631 5.6e-106 391.0 Lactobacillaceae 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 R00704 RC00044 ko00000,ko00001,ko01000 Bacteria 1TSZ6@1239,3F4US@33958,4HCIS@91061,COG1052@1,COG1052@2 NA|NA|NA CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family KIAJIJGH_01759 334390.LAF_1657 7.8e-299 1032.3 Lactobacillaceae ybeC Bacteria 1TPJH@1239,3FCAM@33958,4HUE6@91061,COG0531@1,COG0531@2 NA|NA|NA E amino acid KIAJIJGH_01760 334390.LAF_1656 1.2e-134 485.7 Lactobacillaceae pnuC ko:K03811 ko00000,ko02000 4.B.1.1 Bacteria 1UYDN@1239,3F469@33958,4HJE5@91061,COG3201@1,COG3201@2 NA|NA|NA H nicotinamide mononucleotide transporter KIAJIJGH_01761 334390.LAF_1655 2.3e-81 308.1 Lactobacillaceae menC GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04031 RC01053 ko00000,ko00001,ko00002,ko01000 iYO844.BSU30780 Bacteria 1TQMS@1239,3FB6U@33958,4HBMX@91061,COG4948@1,COG4948@2 NA|NA|NA H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) KIAJIJGH_01762 334390.LAF_1655 9.1e-107 392.9 Lactobacillaceae menC GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04031 RC01053 ko00000,ko00001,ko00002,ko01000 iYO844.BSU30780 Bacteria 1TQMS@1239,3FB6U@33958,4HBMX@91061,COG4948@1,COG4948@2 NA|NA|NA H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) KIAJIJGH_01763 334390.LAF_1654 5e-232 810.1 Lactobacillaceae hflX ko:K03665 ko00000,ko03009 Bacteria 1TNZB@1239,3F4B2@33958,4HACA@91061,COG2262@1,COG2262@2 NA|NA|NA S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis KIAJIJGH_01764 334390.LAF_1653 4.5e-120 437.2 Lactobacillaceae pgm7 5.4.2.11,5.4.2.12 ko:K01834,ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1TQWQ@1239,3F5CT@33958,4HFDZ@91061,COG0406@1,COG0406@2 NA|NA|NA G phosphoglycerate mutase KIAJIJGH_01765 334390.LAF_1652 4.3e-118 430.6 Lactobacillaceae dedA ko:K03975 ko00000 Bacteria 1UZ4P@1239,3F51Q@33958,4HG3F@91061,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein KIAJIJGH_01766 334390.LAF_1651 0.0 1483.4 Lactobacillaceae helD 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Bacteria 1TP39@1239,3F486@33958,4H9Y5@91061,COG3973@1,COG3973@2 NA|NA|NA L DNA helicase KIAJIJGH_01767 334390.LAF_1650 2.5e-161 574.7 Lactobacillaceae Bacteria 1TPUW@1239,3F5JP@33958,4HDIE@91061,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family KIAJIJGH_01768 334390.LAF_1649 0.0 1377.5 Lactobacillaceae ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 R05081,R10849 RC00017 ko00000,ko00001,ko01000 Bacteria 1TRMA@1239,3F3R7@33958,4H9S0@91061,COG1368@1,COG1368@2 NA|NA|NA M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily KIAJIJGH_01769 334390.LAF_1648 3.4e-135 487.6 Lactobacillaceae Bacteria 1TPHT@1239,3FC9Q@33958,4HVYE@91061,COG1028@1,COG1028@2 NA|NA|NA IQ Dehydrogenase reductase KIAJIJGH_01770 334390.LAF_1647 1.9e-103 381.7 Lactobacillaceae 2.3.1.128 ko:K03789 ko00000,ko01000,ko03009 Bacteria 1VEW7@1239,3F5HK@33958,4HPE4@91061,COG0454@1,COG0456@2 NA|NA|NA K acetyltransferase KIAJIJGH_01771 334390.LAF_1646 5.3e-175 620.2 Lactobacillaceae coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 iECDH1ME8569_1439.ECDH1ME8569_3838,iECH74115_1262.ECH74115_5439,iECSE_1348.ECSE_4265,iECSF_1327.ECSF_3833,iECSP_1301.ECSP_5045,iECW_1372.ECW_m4332,iEcDH1_1363.EcDH1_4016,iEcolC_1368.EcolC_4046,iPC815.YPO3758,iSFV_1184.SFV_4047,iSFxv_1172.SFxv_4418,iWFL_1372.ECW_m4332,iZ_1308.Z5545 Bacteria 1TPHJ@1239,3F42Q@33958,4HA4K@91061,COG1072@1,COG1072@2 NA|NA|NA F Pantothenic acid kinase KIAJIJGH_01772 1423806.JCM15457_1809 8.4e-131 473.8 Lactobacillaceae sptS 2.7.13.3 ko:K11328 ko02020,map02020 M00464 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1UHQH@1239,3F4JY@33958,4HAHG@91061,COG0642@1,COG0642@2 NA|NA|NA T Histidine kinase KIAJIJGH_01773 1423806.JCM15457_1808 6.2e-80 303.9 Lactobacillaceae Bacteria 1TPU2@1239,3F53G@33958,4HG2E@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator KIAJIJGH_01774 334390.LAF_1644 2.8e-84 317.8 Lactobacillaceae 2.7.6.5 ko:K00951,ko:K07816 ko00230,map00230 R00429 RC00002,RC00078 ko00000,ko00001,ko01000 Bacteria 1TQ2F@1239,3F518@33958,4IQWD@91061,COG2357@1,COG2357@2 NA|NA|NA T Region found in RelA / SpoT proteins KIAJIJGH_01775 525309.HMPREF0494_0690 5.7e-270 936.4 Lactobacillaceae guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.3.1.128,6.3.5.2 ko:K01951,ko:K03790 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002,ko03009 iLJ478.TM1820 Bacteria 1TPG8@1239,3F3NV@33958,4HA7Q@91061,COG0519@1,COG0519@2 NA|NA|NA F Catalyzes the synthesis of GMP from XMP KIAJIJGH_01776 334390.LAF_1643 0.0 1570.1 Lactobacillaceae norZ 1.7.2.5 ko:K04561 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002,ko01000 3.D.4.10 Bacteria 1TSW2@1239,3F4ID@33958,4HCFR@91061,COG3256@1,COG3256@2 NA|NA|NA P Cytochrome C and Quinol oxidase polypeptide I KIAJIJGH_01778 334390.LAF_1642 0.0 1715.7 Lactobacillaceae pacL 3.6.3.8,3.6.3.9 ko:K01537,ko:K01539 ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978 ko00000,ko00001,ko01000,ko04147 3.A.3.1,3.A.3.2 Bacteria 1TPF5@1239,3FC0Z@33958,4HTQ4@91061,COG0474@1,COG0474@2 NA|NA|NA P Cation transporter/ATPase, N-terminus KIAJIJGH_01779 334390.LAF_1641 2.6e-84 318.2 Lactobacillaceae Bacteria 1U5CK@1239,2ACE2@1,311ZJ@2,3F5IZ@33958,4IF3R@91061 NA|NA|NA KIAJIJGH_01781 334390.LAF_1639 1.4e-104 385.6 Firmicutes Bacteria 1VZSI@1239,29W71@1,30HS8@2 NA|NA|NA S Domain of unknown function (DUF4767) KIAJIJGH_01782 334390.LAF_1638 1.1e-30 138.7 Lactobacillaceae Bacteria 1V79H@1239,3F7XM@33958,4HIV4@91061,COG0640@1,COG0640@2 NA|NA|NA K Helix-turn-helix domain KIAJIJGH_01783 334390.LAF_1638 1.2e-10 72.4 Lactobacillaceae Bacteria 1V79H@1239,3F7XM@33958,4HIV4@91061,COG0640@1,COG0640@2 NA|NA|NA K Helix-turn-helix domain KIAJIJGH_01784 334390.LAF_1637 1.8e-173 615.1 Lactobacillaceae 1.3.1.9 ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 Bacteria 1TPC3@1239,3F4PC@33958,4H9T0@91061,COG2070@1,COG2070@2 NA|NA|NA S Nitronate monooxygenase KIAJIJGH_01786 1423734.JCM14202_4064 2.3e-30 138.7 Lactobacillaceae Bacteria 1TRSF@1239,3F4DZ@33958,4HCMP@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair KIAJIJGH_01787 1423775.BAMN01000031_gene132 1e-73 283.5 Lactobacillaceae ydjP Bacteria 1TR25@1239,3F4FI@33958,4HMJ7@91061,COG2267@1,COG2267@2 NA|NA|NA I Alpha/beta hydrolase family KIAJIJGH_01788 944562.HMPREF9102_1353 7.8e-20 103.2 Lactobacillaceae citG 2.4.2.52,2.7.7.61 ko:K05964,ko:K05966,ko:K13927,ko:K13930 ko02020,map02020 R09675,R10706 RC00049,RC00063 ko00000,ko00001,ko01000 Bacteria 1TQGQ@1239,3F4SU@33958,4HGCS@91061,COG1767@1,COG1767@2,COG3697@1,COG3697@2 NA|NA|NA H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase KIAJIJGH_01790 525309.HMPREF0494_0755 2e-11 73.9 Lactobacillaceae citG 2.4.2.52,2.7.7.61 ko:K05964,ko:K05966,ko:K13927,ko:K13930 ko02020,map02020 R09675,R10706 RC00049,RC00063 ko00000,ko00001,ko01000 Bacteria 1TQGQ@1239,3F4SU@33958,4HGCS@91061,COG1767@1,COG1767@2,COG3697@1,COG3697@2 NA|NA|NA H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase KIAJIJGH_01791 334390.LAF_0967 1e-34 152.1 Bacteria citG 2.4.2.52,2.7.7.61 ko:K05964,ko:K13927 ko02020,map02020 R09675,R10706 RC00049,RC00063 ko00000,ko00001,ko01000 Bacteria COG3697@1,COG3697@2 NA|NA|NA HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase KIAJIJGH_01792 334390.LAF_0968 4.3e-62 243.8 Lactobacillaceae ydiI Bacteria 1V7G2@1239,3F7FT@33958,4HIIA@91061,COG2050@1,COG2050@2 NA|NA|NA Q Thioesterase superfamily KIAJIJGH_01793 334390.LAF_0969 5.3e-158 563.5 Lactobacillaceae menB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016043,GO:0016829,GO:0016830,GO:0016833,GO:0022607,GO:0034214,GO:0042180,GO:0042181,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0071890,GO:0071944,GO:1901576,GO:1901661,GO:1901663 4.1.3.36 ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07263 RC01923 ko00000,ko00001,ko00002,ko01000 Bacteria 1UHNU@1239,3F5HN@33958,4HAD0@91061,COG0447@1,COG0447@2 NA|NA|NA H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) KIAJIJGH_01794 334390.LAF_0970 3.4e-277 960.3 Lactobacillaceae menE 6.2.1.26 ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04030 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPSX@1239,3F453@33958,4HACS@91061,COG0318@1,COG0318@2 NA|NA|NA H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily KIAJIJGH_01795 334390.LAF_0230 2.8e-156 558.1 Bacilli Bacteria 1VKTK@1239,4I02N@91061,COG1396@1,COG1396@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins KIAJIJGH_01796 1423724.BAMM01000034_gene2133 2.5e-07 60.8 Lactobacillaceae Bacteria 1U701@1239,2DKTD@1,30AQY@2,3F8SS@33958,4IGUB@91061 NA|NA|NA S Helix-turn-helix domain KIAJIJGH_01797 334390.LAF_0027 1.6e-89 336.7 Bacteria ysdA ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria COG1668@1,COG1668@2 NA|NA|NA CP transmembrane transport KIAJIJGH_01798 203123.OEOE_1534 1.8e-71 276.2 Leuconostocaceae natA ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TR06@1239,4AWTH@81850,4H9RX@91061,COG4152@1,COG4152@2 NA|NA|NA S ABC transporter, ATP-binding protein KIAJIJGH_01799 387344.LVIS_A12 4.4e-85 320.9 Lactobacillaceae Bacteria 1VEKB@1239,3F84P@33958,4HH0D@91061,COG1476@1,COG1476@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins KIAJIJGH_01800 1046629.Ssal_01047 4.1e-157 560.8 Bacilli yegU Bacteria 1U2AQ@1239,4HIXT@91061,COG1397@1,COG1397@2 NA|NA|NA O ADP-ribosylglycohydrolase KIAJIJGH_01801 1046629.Ssal_01049 2.9e-83 314.7 Bacilli ko:K03457 ko00000 2.A.39 Bacteria 1TRAH@1239,4IRPE@91061,COG1457@1,COG1457@2 NA|NA|NA F Belongs to the purine-cytosine permease (2.A.39) family KIAJIJGH_01802 1408312.JNJS01000002_gene31 3.2e-59 235.3 Pseudobutyrivibrio ko:K19423 ko00000,ko01000,ko01003 GT2 Bacteria 1UZRX@1239,24HX7@186801,3NI63@46205,COG1215@1,COG1215@2 NA|NA|NA M Glycosyltransferase like family 2 KIAJIJGH_01803 742733.HMPREF9469_03768 3.8e-69 268.9 Clostridia Bacteria 1W2M9@1239,24U16@186801,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 KIAJIJGH_01804 1122217.KB899577_gene1855 3.1e-53 215.7 Negativicutes Bacteria 1V6BK@1239,28PSK@1,2ZCE3@2,4H7NQ@909932 NA|NA|NA KIAJIJGH_01805 1226325.HMPREF1548_05773 6.2e-47 195.3 Clostridiaceae Bacteria 1VI6R@1239,24URZ@186801,28MPD@1,3387A@2,36T46@31979 NA|NA|NA S O-antigen polysaccharide polymerase Wzy KIAJIJGH_01806 334390.LAF_1015 4.1e-217 760.4 Lactobacillaceae argE 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPMJ@1239,3F3N9@33958,4HB39@91061,COG0624@1,COG0624@2 NA|NA|NA E succinyl-diaminopimelate desuccinylase KIAJIJGH_01808 334390.LAF_1017 1.6e-57 228.8 Lactobacillaceae arsC 1.20.4.1 ko:K03741 ko00000,ko01000 Bacteria 1V3JW@1239,3F7YV@33958,4HH49@91061,COG0394@1,COG0394@2 NA|NA|NA T Low molecular weight phosphotyrosine protein phosphatase KIAJIJGH_01809 334390.LAF_1018 1.1e-111 409.5 Lactobacillaceae glpQ1 3.1.4.46 ko:K01126 ko00564,map00564 R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 Bacteria 1V3W4@1239,3F4E3@33958,4HFNQ@91061,COG0584@1,COG0584@2 NA|NA|NA C glycerophosphoryl diester phosphodiesterase KIAJIJGH_01810 1121914.AUDW01000007_gene604 1e-48 199.5 Bacillales incertae sedis yrfB Bacteria 1TPM6@1239,3WE6M@539002,4HAS5@91061,COG1902@1,COG1902@2 NA|NA|NA C NADH:flavin oxidoreductase / NADH oxidase family KIAJIJGH_01811 334390.LAF_1019 1.1e-89 335.9 Lactobacillaceae rmeB Bacteria 1V3QI@1239,3F69R@33958,4HH53@91061,COG0789@1,COG0789@2 NA|NA|NA K transcriptional regulator, MerR family KIAJIJGH_01812 334390.LAF_1020 1.2e-132 479.2 Lactobacillaceae ybbM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 ko:K02069 M00211 ko00000,ko00002,ko02000 9.B.25.1 Bacteria 1UY1N@1239,3F4P1@33958,4HDM4@91061,COG0390@1,COG0390@2 NA|NA|NA S Uncharacterised protein family (UPF0014) KIAJIJGH_01813 334390.LAF_1021 1.4e-110 405.6 Lactobacillaceae ybbL GO:0005575,GO:0005623,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0016020,GO:0019725,GO:0030003,GO:0042592,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071944,GO:0098771 ko:K02065,ko:K02068 ko02010,map02010 M00210,M00211,M00669,M00670 ko00000,ko00001,ko00002,ko02000 3.A.1.27 Bacteria 1V3DQ@1239,3F4UY@33958,4HHGU@91061,COG4619@1,COG4619@2 NA|NA|NA S ABC transporter, ATP-binding protein KIAJIJGH_01814 334390.LAF_1022 0.0 1104.7 Lactobacillaceae alsS 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQE8@1239,3FCE6@33958,4HAV1@91061,COG0028@1,COG0028@2 NA|NA|NA EH Belongs to the TPP enzyme family KIAJIJGH_01815 334390.LAF_1023 0.0 1143.6 Lactobacillaceae ko:K09384 ko00000 Bacteria 1TPQU@1239,3F47M@33958,4HBI0@91061,COG3410@1,COG3410@2 NA|NA|NA N Uncharacterized conserved protein (DUF2075) KIAJIJGH_01817 334390.LAF_1203 8.1e-207 726.1 Lactobacillaceae carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955,ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 iNJ661.Rv1383,iYO844.BSU15510 Bacteria 1TQ8N@1239,3F43R@33958,4H9Z0@91061,COG0505@1,COG0505@2 NA|NA|NA F Carbamoyl-phosphate synthetase glutamine chain KIAJIJGH_01818 1138822.PL11_10625 4e-202 710.7 Lactobacillaceae ko:K07496 ko00000 Bacteria 1TRNY@1239,3F55P@33958,4HBKP@91061,COG0675@1,COG0675@2 NA|NA|NA L transposase, IS605 OrfB family KIAJIJGH_01819 334390.LAF_0082 9.8e-95 352.8 Lactobacillaceae Bacteria 1TRSF@1239,3F3YG@33958,4HADR@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family KIAJIJGH_01821 1302286.BAOT01000069_gene2184 9.8e-26 122.9 Lactobacillaceae Bacteria 1TRSF@1239,3F4DZ@33958,4HCMP@91061,COG2826@1,COG2826@2 NA|NA|NA L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair KIAJIJGH_01822 334390.LAF_1735 0.0 1103.6 Lactobacillaceae ptsI GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0008150,GO:0008643,GO:0008965,GO:0009401,GO:0016740,GO:0016772,GO:0016775,GO:0019197,GO:0032991,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 8.A.7 iB21_1397.B21_02277,iE2348C_1286.E2348C_2602,iEC042_1314.EC042_2625,iECBD_1354.ECBD_1265,iECB_1328.ECB_02316,iECD_1391.ECD_02316,iECH74115_1262.ECH74115_3647,iECIAI1_1343.ECIAI1_2474,iECIAI39_1322.ECIAI39_2562,iECO103_1326.ECO103_2935,iECO111_1330.ECO111_3146,iECO26_1355.ECO26_3469,iECP_1309.ECP_2440,iECSE_1348.ECSE_2707,iECSP_1301.ECSP_3364,iECUMN_1333.ECUMN_2738,iECW_1372.ECW_m2645,iECs_1301.ECs3288,iEKO11_1354.EKO11_1312,iEcE24377_1341.EcE24377A_2703,iEcHS_1320.EcHS_A2551,iEcSMS35_1347.EcSMS35_2571,iEcolC_1368.EcolC_1262,iLF82_1304.LF82_1770,iNRG857_1313.NRG857_12115,iSBO_1134.SBO_2440,iSDY_1059.SDY_2613,iSFV_1184.SFV_2468,iSF_1195.SF2471,iSFxv_1172.SFxv_2720,iSSON_1240.SSON_2505,iS_1188.S2617,iUMNK88_1353.UMNK88_3018,iWFL_1372.ECW_m2645,iZ_1308.Z3682 Bacteria 1TPK8@1239,3F3MS@33958,4H9VD@91061,COG1080@1,COG1080@2 NA|NA|NA G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) KIAJIJGH_01823 334390.LAF_1736 1e-243 849.0 Lactobacillaceae fucP ko:K02429 ko00000,ko02000 2.A.1.7 Bacteria 1TQ1K@1239,3F3U4@33958,4HTTC@91061,COG0738@1,COG0738@2 NA|NA|NA G Major Facilitator Superfamily KIAJIJGH_01824 334390.LAF_1737 1.3e-66 258.8 Lactobacillaceae rbsD GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009056,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016052,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0016887,GO:0017111,GO:0019303,GO:0019321,GO:0019323,GO:0022804,GO:0022857,GO:0034219,GO:0042623,GO:0042626,GO:0042802,GO:0043211,GO:0043492,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:1901575 5.4.99.62 ko:K06726 ko02010,map02010 R08247 RC02247 ko00000,ko00001,ko01000 iAF1260.b3748,iBWG_1329.BWG_3439,iECDH10B_1368.ECDH10B_3936,iECDH1ME8569_1439.ECDH1ME8569_3636,iECH74115_1262.ECH74115_5184,iECSP_1301.ECSP_4798,iECs_1301.ECs4690,iETEC_1333.ETEC_4039,iEcDH1_1363.EcDH1_4219,iJO1366.b3748,iJR904.b3748,iY75_1357.Y75_RS18330 Bacteria 1VA2V@1239,3F6GA@33958,4HIFW@91061,COG1869@1,COG1869@2 NA|NA|NA G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose KIAJIJGH_01825 334390.LAF_1738 5e-165 587.0 Lactobacillaceae rbsK 2.7.1.15 ko:K00852 ko00030,map00030 R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TQRC@1239,3F3S5@33958,4HA87@91061,COG0524@1,COG0524@2 NA|NA|NA H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway KIAJIJGH_01826 334390.LAF_1739 8.3e-171 606.3 Lactobacillaceae deoR GO:0003674,GO:0005488,GO:0005515,GO:0042802 ko:K05346 ko00000,ko03000 Bacteria 1TPUB@1239,3F4PP@33958,4HCAR@91061,COG2390@1,COG2390@2 NA|NA|NA K sugar-binding domain protein KIAJIJGH_01827 334390.LAF_1740 9.8e-115 419.5 Lactobacillaceae deoC GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4,5.4.2.8 ko:K01619,ko:K01840 ko00030,ko00051,ko00520,ko01100,ko01110,ko01130,map00030,map00051,map00520,map01100,map01110,map01130 M00114 R01066,R01818 RC00408,RC00436,RC00437 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPAJ@1239,3F4M3@33958,4HAAJ@91061,COG0274@1,COG0274@2 NA|NA|NA F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate KIAJIJGH_01828 334390.LAF_1741 4.8e-201 706.8 Lactobacillaceae Bacteria 1UE66@1239,28JDC@1,2Z97R@2,3F59E@33958,4IF0R@91061 NA|NA|NA S Domain of unknown function (DUF4432) KIAJIJGH_01829 334390.LAF_1742 3.2e-175 620.9 Lactobacillaceae rbsK 2.7.1.15 ko:K00852 ko00030,map00030 R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 Bacteria 1TQRC@1239,3F3S5@33958,4HA87@91061,COG0524@1,COG0524@2 NA|NA|NA H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway KIAJIJGH_01830 334390.LAF_0020 8.6e-76 289.7 Lactobacillaceae htrA GO:0008150,GO:0009266,GO:0009628,GO:0050896 3.4.21.107 ko:K04691,ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1TRM8@1239,3F45X@33958,4HA31@91061,COG0265@1,COG0265@2 NA|NA|NA O serine protease KIAJIJGH_01831 334390.LAF_0019 2.3e-153 548.1 Lactobacillaceae vicX 3.1.26.11 ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Bacteria 1TQ8E@1239,3F3S4@33958,4HAKD@91061,COG1235@1,COG1235@2 NA|NA|NA S domain protein KIAJIJGH_01832 334390.LAF_0018 1e-142 512.7 Lactobacillaceae yycI Bacteria 1V1FW@1239,3F3PV@33958,4HFWZ@91061,COG4853@1,COG4853@2 NA|NA|NA S YycH protein KIAJIJGH_01833 334390.LAF_0017 2.5e-239 834.3 Lactobacillaceae yycH Bacteria 1V32Y@1239,3F4HR@33958,4HG2Q@91061,COG4863@1,COG4863@2 NA|NA|NA S YycH protein KIAJIJGH_01834 334390.LAF_0016 4.7e-105 387.1 Lactobacillaceae vicK 2.7.13.3 ko:K07652 ko02020,map02020 M00459 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TQ1H@1239,3F45G@33958,4HA52@91061,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase KIAJIJGH_01835 334390.LAF_0016 6.3e-32 142.9 Lactobacillaceae vicK 2.7.13.3 ko:K07652 ko02020,map02020 M00459 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Bacteria 1TQ1H@1239,3F45G@33958,4HA52@91061,COG5002@1,COG5002@2 NA|NA|NA T Histidine kinase KIAJIJGH_01836 334390.LAF_0015 6.8e-130 469.9 Lactobacillaceae Bacteria 1TPQG@1239,3F4FB@33958,4HA8Q@91061,COG0745@1,COG0745@2 NA|NA|NA K response regulator KIAJIJGH_01837 334390.LAF_0020 4.2e-61 240.7 Lactobacillaceae htrA GO:0008150,GO:0009266,GO:0009628,GO:0050896 3.4.21.107 ko:K04691,ko:K04771 ko01503,ko02020,map01503,map02020 M00728 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Bacteria 1TRM8@1239,3F45X@33958,4HA31@91061,COG0265@1,COG0265@2 NA|NA|NA O serine protease KIAJIJGH_01838 334390.LAF_0738 1.3e-254 885.2 Lactobacillaceae ko:K16211 ko00000,ko02000 2.A.2.6 Bacteria 1TRP7@1239,3F3YZ@33958,4HCUK@91061,COG2211@1,COG2211@2 NA|NA|NA G Major Facilitator KIAJIJGH_01839 334390.LAF_0739 0.0 1189.1 Lactobacillaceae malL 3.2.1.10 ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 GH13 Bacteria 1TP53@1239,3F41I@33958,4HA1G@91061,COG0366@1,COG0366@2 NA|NA|NA G Alpha amylase, catalytic domain protein KIAJIJGH_01840 334390.LAF_0740 5.2e-176 623.6 Lactobacillaceae ko:K02529 ko00000,ko03000 Bacteria 1TRFH@1239,3F5CG@33958,4HBNT@91061,COG1609@1,COG1609@2 NA|NA|NA K Transcriptional regulator, LacI family KIAJIJGH_01841 1138822.PL11_00280 4.4e-70 271.6 Lactobacillaceae uvrX 2.7.7.7 ko:K02346,ko:K03502,ko:K14161 ko00000,ko01000,ko03400 Bacteria 1TP42@1239,3F3WN@33958,4HA1P@91061,COG0389@1,COG0389@2 NA|NA|NA L Belongs to the DNA polymerase type-Y family KIAJIJGH_01842 936140.AEOT01000027_gene1177 4.6e-09 67.4 Lactobacillaceae Bacteria 1W2PF@1239,28WF1@1,2ZIF8@2,3F8BE@33958,4HZUK@91061 NA|NA|NA KIAJIJGH_01843 334390.LAF_0741 2.1e-224 784.6 Lactobacillaceae dhaT 1.1.1.1,1.1.1.202 ko:K00086,ko:K13954 ko00010,ko00071,ko00350,ko00561,ko00625,ko00626,ko00640,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00561,map00625,map00626,map00640,map01100,map01110,map01120,map01130,map01220 R00623,R00754,R02377,R03119,R04880,R05233,R05234,R06917,R06927 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649 ko00000,ko00001,ko01000 iYL1228.KPN_03491 Bacteria 1TPB4@1239,3F4SZ@33958,4HAPA@91061,COG1454@1,COG1454@2 NA|NA|NA C Dehydrogenase KIAJIJGH_01844 1033837.WANG_1442 5.8e-32 144.1 Lactobacillaceae Bacteria 1VPHG@1239,2E4B4@1,32Z6U@2,3F890@33958,4HSYW@91061 NA|NA|NA KIAJIJGH_01846 334390.LAF_0076 1.5e-125 455.7 Lactobacillaceae noc ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 1TP0I@1239,3F4RU@33958,4HAC6@91061,COG1475@1,COG1475@2 NA|NA|NA K Belongs to the ParB family KIAJIJGH_01847 334390.LAF_0077 9.5e-147 526.2 Lactobacillaceae spo0J GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 ko:K03497 ko00000,ko03000,ko03036,ko04812 Bacteria 1TQ2B@1239,3F47R@33958,4H9TB@91061,COG1475@1,COG1475@2 NA|NA|NA K Belongs to the ParB family KIAJIJGH_01848 334390.LAF_0078 7.9e-31 139.0 Lactobacillaceae yyzM Bacteria 1VEQ7@1239,3F823@33958,4HNHU@91061,COG4481@1,COG4481@2 NA|NA|NA S Bacterial protein of unknown function (DUF951) KIAJIJGH_01849 334390.LAF_0079 2.2e-199 701.4 Lactobacillaceae ychF GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772 ko:K06942 ko00000,ko03009 Bacteria 1TPRK@1239,3F3TK@33958,4H9SQ@91061,COG0012@1,COG0012@2 NA|NA|NA J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner KIAJIJGH_01850 1423807.BACO01000033_gene951 6.3e-126 457.6 Lactobacillaceae Bacteria 1U5C7@1239,3F5HV@33958,4IF3F@91061,COG4097@1,COG4097@2 NA|NA|NA P FAD-binding domain KIAJIJGH_01851 585506.HMPREF0877_0368 2.9e-54 218.8 Leuconostocaceae apbE 2.7.1.180 ko:K03734 ko00000,ko01000 Bacteria 1VVZ1@1239,4AY4Q@81850,4HWJX@91061,COG1477@1,COG1477@2 NA|NA|NA H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein KIAJIJGH_01852 1423807.BACO01000033_gene949 6.9e-30 137.1 Lactobacillaceae Bacteria 1VBTI@1239,3F7N4@33958,4HKRR@91061,COG3976@1,COG3976@2 NA|NA|NA S FMN_bind KIAJIJGH_01853 908339.HMPREF9265_1762 2.1e-55 221.5 Lactobacillaceae Bacteria 1VEP6@1239,2ECAZ@1,3369B@2,3F5SZ@33958,4HQSU@91061 NA|NA|NA KIAJIJGH_01855 585506.HMPREF0877_0659 8.5e-191 673.7 Leuconostocaceae Bacteria 1UYWB@1239,4AYZJ@81850,4HTZD@91061,COG1807@1,COG1807@2 NA|NA|NA M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family KIAJIJGH_01856 585506.HMPREF0877_0660 2.2e-131 475.3 Leuconostocaceae ykoT ko:K20534 ko00000,ko01000,ko01005,ko02000 4.D.2.1.9 GT2 Bacteria 1TPR3@1239,4AX5T@81850,4HC2Z@91061,COG0463@1,COG0463@2 NA|NA|NA M Glycosyl transferase family 2 KIAJIJGH_01857 585506.HMPREF0877_0661 3.5e-51 208.4 Leuconostocaceae lssY 3.6.1.27 ko:K19302 ko00550,map00550 R05627 RC00002 ko00000,ko00001,ko01000,ko01011 Bacteria 1VY85@1239,4AXIW@81850,4HXM4@91061,COG0671@1,COG0671@2 NA|NA|NA I PAP2 superfamily KIAJIJGH_01858 585506.HMPREF0877_0662 1.4e-84 319.3 Leuconostocaceae dedA ko:K03975 ko00000 Bacteria 1VTUR@1239,4AXZU@81850,4HU34@91061,COG0586@1,COG0586@2 NA|NA|NA S SNARE associated Golgi protein KIAJIJGH_01859 585506.HMPREF0877_0663 7.7e-146 523.9 Leuconostocaceae Bacteria 1VU2I@1239,4AYUQ@81850,4HHZT@91061,COG0642@1,COG2205@2 NA|NA|NA T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain KIAJIJGH_01860 1423734.JCM14202_2006 3.3e-92 344.7 Lactobacillaceae Bacteria 1TS81@1239,3F3JF@33958,4H9NE@91061,COG0745@1,COG0745@2 NA|NA|NA K Transcriptional regulatory protein, C terminal KIAJIJGH_01861 324831.LGAS_1466 1.7e-77 297.0 Lactobacillaceae Bacteria 1TUEW@1239,3F96I@33958,4I4DK@91061,COG5293@1,COG5293@2 NA|NA|NA KIAJIJGH_01862 552811.Dehly_1177 5.1e-20 103.2 Dehalococcoidia Bacteria 2G9X9@200795,34DQ3@301297,COG3655@1,COG3655@2 NA|NA|NA K Cro/C1-type HTH DNA-binding domain KIAJIJGH_01863 525309.HMPREF0494_0910 6.1e-295 1019.6 Lactobacillaceae 2.1.1.72 ko:K03427 ko00000,ko01000,ko02048 Bacteria 1TPGZ@1239,3F4HM@33958,4HA1J@91061,COG0286@1,COG0286@2 NA|NA|NA V type I restriction-modification system KIAJIJGH_01864 218140.BPSY_0287 1e-38 165.6 Bifidobacteriales mdt(A) ko:K08217 br01600,ko00000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.22 Bacteria 2I2EY@201174,4D02G@85004,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily KIAJIJGH_01865 1114972.AUAW01000027_gene730 6.5e-75 286.6 Lactobacillaceae Bacteria 1VA7Q@1239,3F7D0@33958,4HKGF@91061,COG3682@1,COG3682@2 NA|NA|NA K Copper transport repressor CopY TcrY KIAJIJGH_01866 1114972.AUAW01000027_gene731 0.0 1213.0 Lactobacillaceae copB 3.6.3.4 ko:K01533 R00086 RC00002 ko00000,ko01000 3.A.3.5 Bacteria 1TP5S@1239,3F4IX@33958,4HAI0@91061,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase KIAJIJGH_01868 525318.HMPREF0497_1559 2.6e-51 208.8 Lactobacillaceae Bacteria 1V51N@1239,3F51V@33958,4HDX2@91061,COG1961@1,COG1961@2 NA|NA|NA L Resolvase, N terminal domain KIAJIJGH_01869 1423734.JCM14202_217 1.2e-85 322.8 Lactobacillaceae 2.5.1.105 ko:K04088,ko:K06897 ko00790,map00790 M00742 R10339 RC00121 ko00000,ko00001,ko00002,ko01000 Bacteria 1V9B6@1239,3F4M1@33958,4HJTJ@91061,COG0053@1,COG0053@2 NA|NA|NA P Cation efflux family KIAJIJGH_01870 334390.LAF_1820 1.4e-167 596.3 Lactobacillaceae acm2 3.2.1.17 ko:K01185,ko:K02395 ko00000,ko01000,ko02035 Bacteria 1UYRM@1239,3F4XJ@33958,4HAU6@91061,COG1388@1,COG1388@2,COG1705@1,COG1705@2 NA|NA|NA NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase KIAJIJGH_01871 334390.LAF_1821 2.6e-46 191.0 Lactobacillaceae czrA ko:K21903,ko:K22043 ko00000,ko03000 Bacteria 1VA6G@1239,3F7DH@33958,4HKYT@91061,COG0640@1,COG0640@2 NA|NA|NA K Transcriptional regulator, ArsR family KIAJIJGH_01872 334390.LAF_0982 4.4e-31 140.2 Lactobacillaceae Bacteria 1U5WC@1239,2E6DR@1,3311A@2,3F6MC@33958,4IFK0@91061 NA|NA|NA KIAJIJGH_01873 334390.LAF_1838 4.6e-25 119.8 Lactobacillaceae gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 ko:K03495 R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 Bacteria 1TQ4B@1239,3F454@33958,4HA6S@91061,COG0445@1,COG0445@2 NA|NA|NA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 KIAJIJGH_01874 334390.LAF_0983 6.8e-114 417.2 Lactobacillaceae yicL Bacteria 1TR6G@1239,3F5NA@33958,4HAMD@91061,COG0697@1,COG0697@2 NA|NA|NA EG EamA-like transporter family KIAJIJGH_01875 334390.LAF_0984 2.8e-73 281.6 Lactobacillaceae Bacteria 1VE35@1239,2DPC1@1,331GC@2,3F66X@33958,4HMP3@91061 NA|NA|NA S Domain of unknown function (DUF4352) KIAJIJGH_01876 334390.LAF_0986 0.0 1206.4 Lactobacillaceae 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPAR@1239,3F53U@33958,4HAXN@91061,COG1053@1,COG1053@2,COG3976@1,COG3976@2 NA|NA|NA C FAD binding domain KIAJIJGH_01877 334390.LAF_0987 2.8e-168 597.8 Lactobacillaceae Bacteria 1V3HS@1239,3F4HP@33958,4IQPW@91061,COG0583@1,COG0583@2 NA|NA|NA K LysR substrate binding domain KIAJIJGH_01878 334390.LAF_0988 4.1e-161 573.9 Lactobacillaceae rssA Bacteria 1TQ9W@1239,3F52H@33958,4HCHJ@91061,COG4667@1,COG4667@2 NA|NA|NA S Phospholipase, patatin family KIAJIJGH_01879 334390.LAF_0989 1.7e-213 748.4 Lactobacillaceae phbA GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034308,GO:0034309,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046165,GO:0046395,GO:0055114,GO:0071270,GO:0071271,GO:0071704,GO:0072329,GO:1901575,GO:1901576,GO:1901615,GO:1901617 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 iSSON_1240.SSON_3004 Bacteria 1TP07@1239,3F3Q5@33958,4H9RJ@91061,COG0183@1,COG0183@2 NA|NA|NA I Belongs to the thiolase family KIAJIJGH_01880 334390.LAF_0990 7.3e-179 633.3 Lactobacillaceae Bacteria 1TQBF@1239,3F603@33958,4HGFS@91061,COG0628@1,COG0628@2 NA|NA|NA S AI-2E family transporter KIAJIJGH_01881 334390.LAF_0991 9.1e-125 453.0 Lactobacillaceae ko:K07090 ko00000 Bacteria 1V75K@1239,3F6BU@33958,4HEE8@91061,COG0730@1,COG0730@2 NA|NA|NA S membrane transporter protein KIAJIJGH_01882 334390.LAF_0992 3.2e-89 334.3 Lactobacillaceae pgpA 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 R02029 RC00017 ko00000,ko00001,ko01000 Bacteria 1V3I0@1239,3F6QT@33958,4HH4Y@91061,COG1267@1,COG1267@2 NA|NA|NA I Phosphatidylglycerophosphatase A KIAJIJGH_01883 334390.LAF_0993 2.6e-194 684.5 Lactobacillaceae Bacteria 1V4BS@1239,3F3QN@33958,4HJRT@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase KIAJIJGH_01884 334390.LAF_0994 3.5e-227 793.9 Lactobacillaceae Bacteria 1U84T@1239,29QI4@1,30BHJ@2,3FAIY@33958,4II28@91061 NA|NA|NA KIAJIJGH_01886 334390.LAF_0996 1.3e-151 542.3 Lactobacillaceae Bacteria 1V910@1239,3F5UB@33958,4HF90@91061,COG4814@1,COG4814@2 NA|NA|NA S Alpha/beta hydrolase of unknown function (DUF915) KIAJIJGH_01887 334390.LAF_0997 0.0 1558.1 Lactobacillaceae ko:K11009 ko00000,ko02042 Bacteria 1V3AR@1239,3F53M@33958,4HWUN@91061,COG1502@1,COG1502@2 NA|NA|NA I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol KIAJIJGH_01888 334390.LAF_0998 1.1e-164 585.9 Lactobacillaceae fadB4 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 Bacteria 1TPJS@1239,3F4SY@33958,4HA59@91061,COG1250@1,COG1250@2 NA|NA|NA I 3-hydroxyacyl-CoA dehydrogenase KIAJIJGH_01889 334390.LAF_0999 1.2e-163 582.4 Lactobacillaceae endA ko:K15051 ko00000 Bacteria 1V4X2@1239,3F3Y8@33958,4HIF5@91061,COG2169@1,COG2169@2 NA|NA|NA F DNA RNA non-specific endonuclease KIAJIJGH_01890 334390.LAF_1000 8e-268 929.1 Lactobacillaceae pipD ko:K08659 ko00000,ko01000,ko01002 Bacteria 1TQ0F@1239,3F3M4@33958,4HC3G@91061,COG4690@1,COG4690@2 NA|NA|NA E Dipeptidase KIAJIJGH_01892 334390.LAF_1003 1.1e-253 882.1 Lactobacillaceae yifK GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K03293 ko00000 2.A.3.1 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease KIAJIJGH_01894 334390.LAF_1005 0.0 1190.3 Lactobacillaceae dxs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0008661,GO:0009058,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901363,GO:1901576,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP37@1239,3F4RN@33958,4H9QW@91061,COG1154@1,COG1154@2 NA|NA|NA H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) KIAJIJGH_01895 334390.LAF_1006 1.2e-235 822.0 Lactobacillaceae ko:K09384 ko00000 Bacteria 1TPQU@1239,3F47M@33958,4HBI0@91061,COG3410@1,COG3410@2 NA|NA|NA N Uncharacterized conserved protein (DUF2075) KIAJIJGH_01896 557436.Lreu_0956 1.5e-54 219.5 Lactobacillaceae Bacteria 1V6V7@1239,3F417@33958,4HITM@91061,COG0398@1,COG0398@2 NA|NA|NA S SNARE associated Golgi protein KIAJIJGH_01897 334390.LAF_1008 1.3e-78 298.9 Lactobacillaceae ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 Bacteria 1V44G@1239,3F68C@33958,4HH8C@91061,COG0105@1,COG0105@2 NA|NA|NA F Belongs to the NDK family KIAJIJGH_01898 334390.LAF_1009 2.2e-99 368.2 Lactobacillaceae padR Bacteria 1V5J2@1239,3FBD5@33958,4IPMM@91061,COG1695@1,COG1695@2 NA|NA|NA K Virulence activator alpha C-term KIAJIJGH_01899 1423754.BALY01000017_gene387 8.6e-96 356.3 Lactobacillaceae padC ko:K13727 ko00000,ko01000 Bacteria 1UY0X@1239,3F4P4@33958,4HAN3@91061,COG3479@1,COG3479@2 NA|NA|NA Q Phenolic acid decarboxylase KIAJIJGH_01901 334390.LAF_1011 1.3e-75 288.9 Lactobacillaceae Bacteria 1V7GP@1239,3F42R@33958,4HJ4R@91061,COG1835@1,COG1835@2 NA|NA|NA I transferase activity, transferring acyl groups other than amino-acyl groups KIAJIJGH_01903 334390.LAF_1012 6.3e-143 513.5 Lactobacillaceae ko:K02029,ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TT16@1239,3F9BQ@33958,4HD16@91061,COG0834@1,COG0834@2 NA|NA|NA ET Bacterial periplasmic substrate-binding proteins KIAJIJGH_01904 797515.HMPREF9103_01675 1.2e-159 569.7 Lactobacillaceae gshF 6.3.2.2 ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 M00118,M00582 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1TPGX@1239,3F506@33958,4HAMJ@91061,COG2918@1,COG2918@2 NA|NA|NA H Belongs to the glutamate--cysteine ligase type 1 family KIAJIJGH_01905 334390.LAF_1013 2.2e-226 791.2 Lactobacillaceae aadAT ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 R01939 RC00006 ko00000,ko00001,ko01000 Bacteria 1TPS5@1239,3F4AH@33958,4H9M3@91061,COG1167@1,COG1167@2 NA|NA|NA EK Aminotransferase, class I KIAJIJGH_01906 334390.LAF_1720 4.3e-74 283.9 Lactobacillaceae glpT ko:K02445 ko00000,ko02000 2.A.1.4.3 Bacteria 1TS33@1239,3F4E6@33958,4HBVJ@91061,COG2271@1,COG2271@2 NA|NA|NA G Major Facilitator Superfamily KIAJIJGH_01907 334390.LAF_1719 6.9e-128 463.8 Lactobacillaceae qmcA GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 Bacteria 1TPXU@1239,3F4HV@33958,4HGRC@91061,COG0330@1,COG0330@2 NA|NA|NA O prohibitin homologues KIAJIJGH_01909 334390.LAF_1717 3.1e-75 287.7 Lactobacillaceae uspA ko:K03499,ko:K06149 ko00000,ko02000 2.A.38.1,2.A.38.4 Bacteria 1VEJR@1239,3F4Z0@33958,4HNHG@91061,COG0589@1,COG0589@2 NA|NA|NA T universal stress protein KIAJIJGH_01910 334390.LAF_1716 1e-58 232.6 Lactobacillaceae Bacteria 1U68K@1239,29P7S@1,30A5V@2,3F7B2@33958,4IFZG@91061 NA|NA|NA KIAJIJGH_01911 1423807.BACO01000018_gene572 8.7e-20 103.6 Lactobacillaceae Bacteria 1UFZH@1239,29V33@1,30GGE@2,3F5BQ@33958,4IF1H@91061 NA|NA|NA KIAJIJGH_01912 334390.LAF_1714 2.2e-159 568.2 Lactobacillaceae Bacteria 1VQQ8@1239,2E39Q@1,32Y99@2,3F4UX@33958,4HRY1@91061 NA|NA|NA KIAJIJGH_01913 334390.LAF_1713 8.4e-75 286.2 Lactobacillaceae Bacteria 1VEC4@1239,3F654@33958,4HM2F@91061,COG1396@1,COG1396@2 NA|NA|NA K Transcriptional regulator KIAJIJGH_01914 334390.LAF_1712 2.4e-186 657.9 Lactobacillaceae ko:K06889 ko00000 Bacteria 1TQYU@1239,3F43H@33958,4HC4H@91061,COG1073@1,COG1073@2 NA|NA|NA D Alpha beta KIAJIJGH_01915 334390.LAF_1711 2.7e-73 281.2 Lactobacillaceae Bacteria 1VY9T@1239,3F7CX@33958,4HXI7@91061,COG1764@1,COG1764@2 NA|NA|NA O OsmC-like protein KIAJIJGH_01916 525309.HMPREF0494_1085 8.2e-73 279.6 Lactobacillaceae Bacteria 1VG8C@1239,2C9NT@1,32ZGB@2,3F749@33958,4HN0V@91061 NA|NA|NA S Protein of unknown function (DUF3290) KIAJIJGH_01917 525309.HMPREF0494_1086 3.5e-109 401.0 Lactobacillaceae yviA Bacteria 1TPNF@1239,3FC4B@33958,4HIDY@91061,COG2323@1,COG2323@2 NA|NA|NA S Protein of unknown function (DUF421) KIAJIJGH_01919 334390.LAF_0412 1.6e-85 322.0 Lactobacillaceae ko:K03830 ko00000,ko01000 Bacteria 1V6S5@1239,3F6HM@33958,4HJJY@91061,COG0454@1,COG0456@2 NA|NA|NA K GNAT family KIAJIJGH_01920 334390.LAF_0413 3.6e-123 447.6 Lactobacillaceae XK27_08875 Bacteria 1VW9X@1239,3F60X@33958,4HWF8@91061,COG5549@1,COG5549@2 NA|NA|NA O PFAM peptidase M10A and M12B, matrixin and adamalysin KIAJIJGH_01921 334390.LAF_0414 3.4e-160 570.9 Lactobacillaceae ytbE 1.1.1.346 ko:K06221 R08878 RC00089 ko00000,ko01000 Bacteria 1TPM1@1239,3FB4T@33958,4HARE@91061,COG0656@1,COG0656@2 NA|NA|NA S Aldo keto reductase KIAJIJGH_01922 334390.LAF_0415 1.7e-145 521.9 Lactobacillaceae tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 iHN637.CLJU_RS19265 Bacteria 1TP2F@1239,3F494@33958,4HAPT@91061,COG0149@1,COG0149@2 NA|NA|NA G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) KIAJIJGH_01923 334390.LAF_0416 3.1e-130 471.1 Lactobacillaceae budA GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0047605 4.1.1.5 ko:K01575 ko00650,ko00660,map00650,map00660 R02948 RC00812 ko00000,ko00001,ko01000 Bacteria 1V4AH@1239,3F41S@33958,4HJ98@91061,COG3527@1,COG3527@2 NA|NA|NA H Belongs to the alpha-acetolactate decarboxylase family KIAJIJGH_01925 334390.LAF_0417 1e-56 225.7 Lactobacillaceae Bacteria 1W08C@1239,2FI40@1,349WT@2,3F7QX@33958,4HYGC@91061 NA|NA|NA KIAJIJGH_01927 557436.Lreu_0443 1.1e-06 60.5 Lactobacillaceae Bacteria 1VQCC@1239,2DI2W@1,33GVK@2,3F8BF@33958,4HR7Z@91061 NA|NA|NA KIAJIJGH_01928 334390.LAF_0418 1.8e-78 298.5 Lactobacillaceae Bacteria 1TTKV@1239,3F7IS@33958,4IG35@91061,COG1846@1,COG1846@2 NA|NA|NA K Winged helix DNA-binding domain KIAJIJGH_01929 334390.LAF_0419 0.0 1083.6 Lactobacillaceae lmrA GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,3F3SP@33958,4H9SC@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter, ATP-binding protein KIAJIJGH_01930 334390.LAF_0420 0.0 1166.0 Lactobacillaceae yfiC ko:K06147 ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 Bacteria 1TP0B@1239,3F3PD@33958,4HA3S@91061,COG1132@1,COG1132@2 NA|NA|NA V ABC transporter KIAJIJGH_01931 334390.LAF_0421 8.2e-193 679.5 Lactobacillaceae ampC Bacteria 1U828@1239,3FBDZ@33958,4HA0Q@91061,COG1680@1,COG1680@2 NA|NA|NA V Beta-lactamase KIAJIJGH_01932 334390.LAF_0422 3.2e-286 990.3 Lactobacillaceae cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0032502,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 ko:K06131 ko00564,ko01100,map00564,map01100 R07390 RC00017 ko00000,ko00001,ko01000 Bacteria 1TPKY@1239,3F3SF@33958,4H9TI@91061,COG1502@1,COG1502@2 NA|NA|NA I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol KIAJIJGH_01933 334390.LAF_0423 6.3e-48 196.4 Lactobacillaceae Bacteria 1U6YW@1239,29PEK@1,315VH@2,3F8QZ@33958,4IGT4@91061 NA|NA|NA KIAJIJGH_01934 334390.LAF_0424 7.5e-140 503.1 Lactobacillaceae cobQ ko:K07009 ko00000 Bacteria 1UYMA@1239,3FBI0@33958,4HEXH@91061,COG3442@1,COG3442@2 NA|NA|NA S CobB/CobQ-like glutamine amidotransferase domain KIAJIJGH_01935 334390.LAF_0425 7.5e-263 912.5 Lactobacillaceae murF 6.3.2.10,6.3.2.13 ko:K01928,ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 R02788,R04573,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1TRG9@1239,3FBS5@33958,4HAMY@91061,COG0770@1,COG0770@2 NA|NA|NA M Domain of unknown function (DUF1727) KIAJIJGH_01936 334390.LAF_0426 3.2e-109 401.0 Lactobacillaceae tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 iAF1260.b1238,iBWG_1329.BWG_1065,iECDH10B_1368.ECDH10B_1298,iECDH1ME8569_1439.ECDH1ME8569_1176,iEcDH1_1363.EcDH1_2411,iJO1366.b1238,iJR904.b1238,iPC815.YPO2176,iY75_1357.Y75_RS06470 Bacteria 1TRVM@1239,3F4UE@33958,4HA4A@91061,COG1435@1,COG1435@2 NA|NA|NA F thymidine kinase KIAJIJGH_01937 334390.LAF_0427 1.2e-154 552.7 Lactobacillaceae prfA ko:K02835 ko00000,ko03012 Bacteria 1TQ7V@1239,3F3Q0@33958,4H9MB@91061,COG0216@1,COG0216@2 NA|NA|NA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA KIAJIJGH_01938 334390.LAF_0428 7.1e-158 563.1 Lactobacillaceae prmB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009007,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0032775,GO:0034641,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044728,GO:0046483,GO:0071704,GO:0090304,GO:0140096,GO:0140097,GO:1901360,GO:1901564 2.1.1.297,2.1.1.298 ko:K02493,ko:K07320 R10806 RC00003,RC03279 ko00000,ko01000,ko03009,ko03012 Bacteria 1TSMA@1239,3F460@33958,4HC6W@91061,COG2890@1,COG2890@2 NA|NA|NA J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif KIAJIJGH_01939 334390.LAF_0429 1.5e-194 685.3 Lactobacillaceae ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87,3.1.3.48 ko:K01104,ko:K07566 R10463 RC00745 ko00000,ko01000,ko03009,ko03016 Bacteria 1TP1I@1239,3F3T1@33958,4HA7W@91061,COG0009@1,COG0009@2 NA|NA|NA J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine KIAJIJGH_01940 334390.LAF_0430 1.3e-229 802.0 Lactobacillaceae glyA 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 Bacteria 1TQVM@1239,3F4C1@33958,4HA5K@91061,COG0112@1,COG0112@2 NA|NA|NA E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism KIAJIJGH_01941 334390.LAF_0431 1.2e-114 419.1 Lactobacillaceae upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000 iSB619.SA_RS11010 Bacteria 1TPMT@1239,3F4M0@33958,4H9Y0@91061,COG0035@1,COG0035@2 NA|NA|NA F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate KIAJIJGH_01942 334390.LAF_0432 5.3e-185 653.7 Lactobacillaceae yibE Bacteria 1TPEV@1239,3F3M9@33958,4HCP3@91061,COG5438@1,COG5438@2 NA|NA|NA S overlaps another CDS with the same product name KIAJIJGH_01943 334390.LAF_0433 3.3e-125 454.5 Lactobacillaceae yibF Bacteria 1TSWX@1239,3F3S6@33958,4HBKX@91061,COG5438@1,COG5438@2 NA|NA|NA S overlaps another CDS with the same product name KIAJIJGH_01944 334390.LAF_0434 5.4e-218 763.5 Lactobacillaceae pyrP ko:K02824,ko:K03458,ko:K16169 ko00000,ko02000 2.A.40,2.A.40.1.1,2.A.40.1.2,2.A.40.3.1 iLJ478.TM0819 Bacteria 1TQKX@1239,3F3UJ@33958,4HAEU@91061,COG2233@1,COG2233@2 NA|NA|NA F Permease KIAJIJGH_01945 334390.LAF_0435 5.8e-129 466.8 Lactobacillaceae atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 iAPECO1_1312.APECO1_2725,iE2348C_1286.E2348C_4048,iEC042_1314.EC042_4125,iECABU_c1320.ECABU_c42230,iECED1_1282.ECED1_4428,iECIAI39_1322.ECIAI39_4342,iECNA114_1301.ECNA114_3887,iECOK1_1307.ECOK1_4187,iECP_1309.ECP_3937,iECS88_1305.ECS88_4160,iECSF_1327.ECSF_3586,iECUMN_1333.ECUMN_4268,iEcSMS35_1347.EcSMS35_4106,iLF82_1304.LF82_0192,iNRG857_1313.NRG857_18615,iUMN146_1321.UM146_18880,iUMNK88_1353.UMNK88_4550,iUTI89_1310.UTI89_C4293,ic_1306.c4666 Bacteria 1TQIT@1239,3F3RE@33958,4H9NV@91061,COG0356@1,COG0356@2 NA|NA|NA C it plays a direct role in the translocation of protons across the membrane KIAJIJGH_01946 334390.LAF_0436 1.2e-16 92.0 Lactobacillaceae atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 1VEHP@1239,3F82A@33958,4HNKQ@91061,COG0636@1,COG0636@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation KIAJIJGH_01947 334390.LAF_0437 3.7e-53 214.5 Lactobacillaceae atpF ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iHN637.CLJU_RS01170,iYO844.BSU36850 Bacteria 1VB85@1239,3F5M8@33958,4HM64@91061,COG0711@1,COG0711@2 NA|NA|NA C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) KIAJIJGH_01948 334390.LAF_0438 3.7e-91 340.9 Lactobacillaceae atpH GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 Bacteria 1VAG3@1239,3FC80@33958,4HKFW@91061,COG0712@1,COG0712@2 NA|NA|NA C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation KIAJIJGH_01949 334390.LAF_0439 4e-284 983.4 Lactobacillaceae atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187 Bacteria 1TNZ8@1239,3F3R4@33958,4HAMZ@91061,COG0056@1,COG0056@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit KIAJIJGH_01950 334390.LAF_0440 2.3e-165 588.2 Lactobacillaceae atpG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iLJ478.TM1611,iSB619.SA_RS10970,iYO844.BSU36820 Bacteria 1TPBX@1239,3F40E@33958,4HB0E@91061,COG0224@1,COG0224@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex KIAJIJGH_01951 334390.LAF_0441 4.4e-253 880.2 Lactobacillaceae atpD 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 iSB619.SA_RS10965 Bacteria 1TPGF@1239,3F3TF@33958,4HAT6@91061,COG0055@1,COG0055@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits KIAJIJGH_01952 334390.LAF_0442 4.4e-68 263.8 Lactobacillaceae atpC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 ko00000,ko00001,ko00002,ko00194 3.A.2.1 iJN746.PP_5412,iSbBS512_1146.SbBS512_E4190 Bacteria 1VA89@1239,3F6I6@33958,4HKHS@91061,COG0355@1,COG0355@2 NA|NA|NA C Produces ATP from ADP in the presence of a proton gradient across the membrane KIAJIJGH_01953 334390.LAF_0443 2.8e-29 134.0 Lactobacillaceae Bacteria 1U79C@1239,29PZU@1,30AY9@2,3F95C@33958,4IH47@91061 NA|NA|NA S Protein of unknown function (DUF1146) KIAJIJGH_01954 334390.LAF_0444 5.5e-220 770.0 Lactobacillaceae murA 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 R00660 RC00350 ko00000,ko00001,ko01000,ko01011 Bacteria 1TPAU@1239,3F795@33958,4H9KI@91061,COG0766@1,COG0766@2 NA|NA|NA M EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) KIAJIJGH_01955 334390.LAF_0445 2.6e-183 647.9 Lactobacillaceae mbl ko:K03569 ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 Bacteria 1TP51@1239,3F463@33958,4HA4S@91061,COG1077@1,COG1077@2 NA|NA|NA D Cell shape determining protein MreB Mrl KIAJIJGH_01956 334390.LAF_0447 7.9e-32 142.5 Lactobacillaceae Bacteria 1U6D6@1239,2BRKM@1,32KJX@2,3F7N5@33958,4IG4Y@91061 NA|NA|NA S Protein of unknown function (DUF2969) KIAJIJGH_01957 334390.LAF_0448 5.8e-222 776.5 Lactobacillaceae rodA ko:K05837 ko00000,ko03036 Bacteria 1TPGH@1239,3F4J4@33958,4HAV4@91061,COG0772@1,COG0772@2 NA|NA|NA D Belongs to the SEDS family KIAJIJGH_01959 334390.LAF_0450 1.5e-180 638.6 Lactobacillaceae Bacteria 1V3Z9@1239,29SNM@1,30DU7@2,3F3VM@33958,4HHKX@91061 NA|NA|NA S Protein of unknown function (DUF2785) KIAJIJGH_01960 334390.LAF_0451 2.9e-215 754.2 Lactobacillaceae ddl 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1TP2Y@1239,3F41Z@33958,4H9KB@91061,COG1181@1,COG1181@2 NA|NA|NA F Belongs to the D-alanine--D-alanine ligase family KIAJIJGH_01961 334390.LAF_1722 1.1e-135 489.2 Lactobacillaceae tal 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP4Q@1239,3F5F6@33958,4HA8G@91061,COG0176@1,COG0176@2 NA|NA|NA H Transaldolase/Fructose-6-phosphate aldolase KIAJIJGH_01962 334390.LAF_1721 0.0 1315.1 Lactobacillaceae tkt 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPIB@1239,3F4IJ@33958,4HADA@91061,COG0021@1,COG0021@2 NA|NA|NA H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate KIAJIJGH_01963 334390.LAF_1767 5.4e-234 816.6 Lactobacillaceae gltP GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0008150,GO:0015711,GO:0015849,GO:0016020,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0071702,GO:0071944 ko:K03309,ko:K11102 ko00000,ko02000 2.A.23,2.A.23.1.1,2.A.23.1.2 iPC815.YPO0254,iYO844.BSU10220 Bacteria 1TPME@1239,3F4Q2@33958,4H9T7@91061,COG1301@1,COG1301@2 NA|NA|NA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family KIAJIJGH_01964 334390.LAF_0045 4.4e-258 896.7 Lactobacillaceae gabD 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 Bacteria 1TP4S@1239,3F47F@33958,4H9MF@91061,COG1012@1,COG1012@2 NA|NA|NA C Belongs to the aldehyde dehydrogenase family KIAJIJGH_01965 334390.LAF_0224 1.2e-290 1005.0 Lactobacillaceae lysS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TP2P@1239,3F439@33958,4H9X4@91061,COG1190@1,COG1190@2 NA|NA|NA J Belongs to the class-II aminoacyl-tRNA synthetase family KIAJIJGH_01966 334390.LAF_0223 5.4e-189 666.8 Lactobacillaceae dus ko:K05540 ko00000,ko01000,ko03016 Bacteria 1TQ2R@1239,3F4C6@33958,4HA9K@91061,COG0042@1,COG0042@2 NA|NA|NA J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines KIAJIJGH_01967 334390.LAF_0222 2.2e-162 578.2 Lactobacillaceae hslO GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0031647,GO:0036506,GO:0042026,GO:0042802,GO:0043167,GO:0043169,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0065007,GO:0065008 ko:K04083 ko00000,ko03110 Bacteria 1TRCH@1239,3F42B@33958,4HAFR@91061,COG1281@1,COG1281@2 NA|NA|NA O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress KIAJIJGH_01968 334390.LAF_0221 0.0 1130.5 Lactobacillaceae ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 ko:K03798 M00742 ko00000,ko00002,ko01000,ko01002,ko03110 Bacteria 1TPTV@1239,3F49Z@33958,4HAJB@91061,COG0465@1,COG0465@2 NA|NA|NA O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins KIAJIJGH_01969 334390.LAF_0220 4.1e-98 364.0 Lactobacillaceae hpt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 Bacteria 1V1C9@1239,3F56C@33958,4HFZ2@91061,COG0634@1,COG0634@2 NA|NA|NA F Belongs to the purine pyrimidine phosphoribosyltransferase family KIAJIJGH_01970 334390.LAF_0219 6.9e-256 889.4 Lactobacillaceae tilS 2.4.2.8,6.3.4.19 ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 R01132,R01229,R02142,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 Bacteria 1TPXP@1239,3F4GY@33958,4H9ZM@91061,COG0037@1,COG0037@2 NA|NA|NA J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine KIAJIJGH_01971 334390.LAF_0218 3e-87 327.8 Lactobacillaceae yabR ko:K07570,ko:K07571 ko00000 Bacteria 1V6FE@1239,3F6HV@33958,4HIKM@91061,COG1098@1,COG1098@2 NA|NA|NA J RNA binding KIAJIJGH_01972 334390.LAF_0217 1.5e-56 225.3 Bacilli divIC ko:K05589,ko:K13052 ko00000,ko03036 Bacteria 1VKC5@1239,4HR53@91061,COG2919@1,COG2919@2 NA|NA|NA D Septum formation initiator KIAJIJGH_01973 334390.LAF_0216 1.6e-39 168.3 Lactobacillaceae yabO GO:0008150,GO:0040007 Bacteria 1VEI5@1239,3F7JX@33958,4HKJJ@91061,COG1188@1,COG1188@2 NA|NA|NA J S4 domain protein KIAJIJGH_01974 334390.LAF_0215 0.0 2279.6 Lactobacillaceae mfd ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Bacteria 1TPF1@1239,3F4KU@33958,4H9NB@91061,COG1197@1,COG1197@2 NA|NA|NA L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site KIAJIJGH_01975 334390.LAF_0214 8.2e-102 376.3 Lactobacillaceae pth GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 ko00000,ko01000,ko03012 Bacteria 1V3NB@1239,3F3VZ@33958,4HH2Z@91061,COG0193@1,COG0193@2 NA|NA|NA J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis KIAJIJGH_01976 334390.LAF_0213 8.1e-114 416.4 Lactobacillaceae Bacteria 1TR5G@1239,3F3JY@33958,4H9ZA@91061,COG0517@1,COG0517@2 NA|NA|NA S (CBS) domain KIAJIJGH_01977 334390.LAF_0212 5e-57 226.9 Lactobacillaceae ko:K07171 ko00000,ko01000,ko02048 Bacteria 1V6DK@1239,3F6Y9@33958,4HGXF@91061,COG2337@1,COG2337@2 NA|NA|NA L Toxic component of a toxin-antitoxin (TA) module KIAJIJGH_01978 334390.LAF_0211 2.4e-209 734.6 Lactobacillaceae alr 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 R00401 RC00285 ko00000,ko00001,ko01000,ko01011 Bacteria 1TNYY@1239,3F3X2@33958,4HA95@91061,COG0787@1,COG0787@2 NA|NA|NA E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids KIAJIJGH_01979 334390.LAF_0210 8.5e-60 236.1 Lactobacillaceae acpS 2.7.6.3,2.7.8.7,5.1.1.1 ko:K00950,ko:K00997,ko:K01775 ko00473,ko00770,ko00790,ko01100,ko01502,map00473,map00770,map00790,map01100,map01502 M00126,M00841 R00401,R01625,R03503 RC00002,RC00017,RC00285 ko00000,ko00001,ko00002,ko01000,ko01011 iYO844.BSU04620 Bacteria 1VA0T@1239,3F6HC@33958,4HKBI@91061,COG0736@1,COG0736@2 NA|NA|NA I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein KIAJIJGH_01980 334390.LAF_0209 1.6e-253 881.7 Lactobacillaceae cshA GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Bacteria 1TPAP@1239,3F46Q@33958,4HAB3@91061,COG0513@1,COG0513@2 NA|NA|NA F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity KIAJIJGH_01981 334390.LAF_0208 2.1e-260 904.4 Lactobacillaceae murF 6.3.2.10,6.3.2.13 ko:K01928,ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 R02788,R04573,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 Bacteria 1VT78@1239,3F4SK@33958,4HACR@91061,COG0770@1,COG0770@2 NA|NA|NA M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein KIAJIJGH_01982 334390.LAF_0207 4.9e-157 560.5 Lactobacillaceae htpX ko:K03799 M00743 ko00000,ko00002,ko01000,ko01002 Bacteria 1TP23@1239,3F40Z@33958,4HB11@91061,COG0501@1,COG0501@2 NA|NA|NA O Belongs to the peptidase M48B family KIAJIJGH_01983 334390.LAF_0206 8.7e-88 329.7 Lactobacillaceae lemA ko:K03744 ko00000 Bacteria 1V3Z0@1239,3F4TF@33958,4HH6H@91061,COG1704@1,COG1704@2 NA|NA|NA S LemA family KIAJIJGH_01984 1203076.CAKF01000021_gene1543 4.8e-47 194.1 Lactobacillaceae ptpA 3.1.3.48 ko:K01104,ko:K20945 ko05111,map05111 ko00000,ko00001,ko01000 Bacteria 1V6SG@1239,3F74A@33958,4HIZN@91061,COG0394@1,COG0394@2 NA|NA|NA T Belongs to the low molecular weight phosphotyrosine protein phosphatase family KIAJIJGH_01985 334390.LAF_0205 4.7e-123 447.2 Lactobacillaceae srtA 3.4.22.70 ko:K07284 ko00000,ko01000,ko01002,ko01011 Bacteria 1V83Z@1239,3F54V@33958,4HJV9@91061,COG3764@1,COG3764@2 NA|NA|NA M sortase family KIAJIJGH_01986 913848.AELK01000086_gene329 8.9e-44 183.7 Lactobacillaceae ko:K09017 ko00000,ko03000 Bacteria 1VG1F@1239,3F6KD@33958,4HPER@91061,COG1309@1,COG1309@2 NA|NA|NA K Transcriptional regulator KIAJIJGH_01987 913848.AELK01000086_gene330 3.5e-137 495.4 Lactobacillaceae ko:K01992 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1TPIG@1239,3F4PV@33958,4H9SK@91061,COG3559@1,COG3559@2 NA|NA|NA M Exporter of polyketide antibiotics KIAJIJGH_01988 913848.AELK01000086_gene331 1.7e-120 439.1 Lactobacillaceae ecsA_1 ko:K01990 M00254 ko00000,ko00002,ko02000 3.A.1 Bacteria 1UHNM@1239,3FBW2@33958,4IS4J@91061,COG4152@1,COG4152@2 NA|NA|NA S ABC transporter KIAJIJGH_01989 334390.LAF_1709 0.0 1197.6 Lactobacillaceae yjcE GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 ko:K03316 ko00000 2.A.36 Bacteria 1TR4G@1239,3F42V@33958,4HBJR@91061,COG0025@1,COG0025@2 NA|NA|NA P Sodium proton antiporter KIAJIJGH_01990 1423814.HMPREF0549_1208 8.8e-17 93.2 Lactobacillaceae yvlA Bacteria 1VIUB@1239,2DZIG@1,32VBI@2,3F7EN@33958,4HRZP@91061 NA|NA|NA KIAJIJGH_01991 334390.LAF_1707 4.9e-114 417.2 Lactobacillaceae ko:K16785 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1V679@1239,3FBEQ@33958,4HFRQ@91061,COG0619@1,COG0619@2 NA|NA|NA P Cobalt transport protein KIAJIJGH_01992 334390.LAF_1707 3.1e-50 204.9 Lactobacillaceae ko:K16785 ko02010,map02010 M00582 ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1V679@1239,3FBEQ@33958,4HFRQ@91061,COG0619@1,COG0619@2 NA|NA|NA P Cobalt transport protein KIAJIJGH_01993 334390.LAF_1706 8.3e-257 892.5 Lactobacillaceae cbiO1 ko:K05776,ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00189,M00582 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 Bacteria 1UI2R@1239,3F3WM@33958,4ISG8@91061,COG0488@1,COG0488@2 NA|NA|NA S ABC transporter, ATP-binding protein KIAJIJGH_01994 334390.LAF_1705 5.9e-100 370.2 Lactobacillaceae ko:K16925 M00582 ko00000,ko00002,ko02000 3.A.1.30 Bacteria 1V39N@1239,3F4QM@33958,4HF32@91061,COG4721@1,COG4721@2 NA|NA|NA S ABC-type cobalt transport system, permease component KIAJIJGH_01995 334390.LAF_1704 2e-180 638.3 Lactobacillaceae iunH2 3.2.2.1 ko:K01239,ko:K01250 ko00230,ko00760,ko01100,map00230,map00760,map01100 R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 Bacteria 1TSAR@1239,3F4A3@33958,4HDCS@91061,COG1957@1,COG1957@2 NA|NA|NA F nucleoside hydrolase KIAJIJGH_01996 334390.LAF_1703 4.4e-183 647.1 Lactobacillaceae yumC GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 1.18.1.2,1.19.1.1,1.8.1.9 ko:K00384,ko:K21567 ko00450,map00450 R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 iYO844.BSU32110 Bacteria 1TRPN@1239,3F3NQ@33958,4H9V7@91061,COG0492@1,COG0492@2 NA|NA|NA C Ferredoxin--NADP reductase KIAJIJGH_01997 334390.LAF_1702 0.0 1112.4 Lactobacillaceae cadA 3.6.3.3,3.6.3.5 ko:K01534 ko00000,ko01000 3.A.3.6 Bacteria 1TQ07@1239,3F4T3@33958,4H9SP@91061,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase KIAJIJGH_01998 334390.LAF_1701 9.6e-33 145.6 Lactobacillaceae copZ ko:K07213 ko04978,map04978 ko00000,ko00001 Bacteria 1VFJ8@1239,3F830@33958,4HNY2@91061,COG2608@1,COG2608@2 NA|NA|NA P Heavy-metal-associated domain KIAJIJGH_01999 334390.LAF_1700 8.8e-101 372.9 Lactobacillaceae dps ko:K04047 ko00000,ko03036 Bacteria 1VB1X@1239,3F4SN@33958,4HMJG@91061,COG0783@1,COG0783@2 NA|NA|NA P Belongs to the Dps family KIAJIJGH_02000 334390.LAF_1699 2e-107 395.2 Lactobacillaceae rcfA 4.1.99.16,4.2.3.22,4.2.3.75 ko:K10187,ko:K21562 ko00909,ko01100,ko01110,map00909,map01100,map01110 R07647,R07648,R08543,R09487 RC01832,RC02159,RC02160,RC02183,RC02425,RC02552 ko00000,ko00001,ko01000,ko03000 Bacteria 1UZT0@1239,3FBKF@33958,4HFR2@91061,COG0664@1,COG0664@2 NA|NA|NA K helix_turn_helix, cAMP Regulatory protein KIAJIJGH_02001 334390.LAF_1698 2e-85 321.6 Lactobacillaceae Bacteria 1U62W@1239,29P3K@1,30A1T@2,3F6X0@33958,4IFS1@91061 NA|NA|NA KIAJIJGH_02002 334390.LAF_1697 0.0 1379.4 Lactobacillaceae ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 R05081,R10849 RC00017 ko00000,ko00001,ko01000 Bacteria 1TRMA@1239,3F3R7@33958,4H9S0@91061,COG1368@1,COG1368@2 NA|NA|NA M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily KIAJIJGH_02003 334390.LAF_1696 2.5e-126 458.0 Lactobacillaceae pgm3 Bacteria 1TQWQ@1239,3FC5M@33958,4HFDZ@91061,COG0406@1,COG0406@2 NA|NA|NA G phosphoglycerate mutase family KIAJIJGH_02004 334390.LAF_1695 1.9e-150 538.5 Lactobacillaceae qorB 1.6.5.2 ko:K19267 ko00130,ko01110,map00130,map01110 R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 Bacteria 1TT90@1239,3F4UU@33958,4HC1K@91061,COG0702@1,COG0702@2 NA|NA|NA GM NmrA-like family KIAJIJGH_02005 334390.LAF_1694 2.1e-228 798.1 Lactobacillaceae pbuX GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 ko:K02824,ko:K03458,ko:K16169,ko:K16170 ko00000,ko02000 2.A.40,2.A.40.1.1,2.A.40.1.2,2.A.40.3.1,2.A.40.3.2 iSB619.SA_RS02140 Bacteria 1TNZZ@1239,3F3Y7@33958,4HBAM@91061,COG2233@1,COG2233@2 NA|NA|NA F xanthine permease KIAJIJGH_02006 334390.LAF_1693 3e-170 604.4 Lactobacillaceae corA ko:K03284 ko00000,ko02000 1.A.35.1,1.A.35.3 Bacteria 1TPI8@1239,3F4B8@33958,4HE7S@91061,COG0598@1,COG0598@2 NA|NA|NA P CorA-like Mg2+ transporter protein KIAJIJGH_02007 334390.LAF_1692 9.3e-169 599.4 Lactobacillaceae rluA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 ko00000,ko01000,ko03009 Bacteria 1TSM6@1239,3F50K@33958,4HA7M@91061,COG0564@1,COG0564@2 NA|NA|NA J Responsible for synthesis of pseudouridine from uracil KIAJIJGH_02008 334390.LAF_1691 2.3e-142 511.5 Lactobacillaceae terC ko:K05794 ko00000 Bacteria 1UVIJ@1239,3F3WS@33958,4HEKW@91061,COG0861@1,COG0861@2 NA|NA|NA P membrane KIAJIJGH_02009 334390.LAF_1690 1e-56 225.7 Lactobacillaceae trxA1 ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Bacteria 1VA3Y@1239,3F7I4@33958,4HKKX@91061,COG3118@1,COG3118@2 NA|NA|NA O Belongs to the thioredoxin family KIAJIJGH_02010 334390.LAF_1355 2.1e-126 458.4 Lactobacillaceae 3.1.3.2,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 ko:K01096,ko:K09474,ko:K19302 ko00550,ko00564,ko00740,ko01100,ko02020,map00550,map00564,map00740,map01100,map02020 R00548,R02029,R05627 RC00002,RC00017 ko00000,ko00001,ko01000,ko01011 Bacteria 1VF2U@1239,3F5CM@33958,4HNXR@91061,COG0671@1,COG0671@2 NA|NA|NA I Acid phosphatase homologues KIAJIJGH_02011 334390.LAF_0046 1.9e-95 355.1 Lactobacillaceae pyrR GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 R00966 RC00063 ko00000,ko00001,ko01000,ko03000 iHN637.CLJU_RS05275 Bacteria 1V3GV@1239,3F4SR@33958,4HGYE@91061,COG2065@1,COG2065@2 NA|NA|NA F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant KIAJIJGH_02012 334390.LAF_0047 4.1e-130 470.7 Lactobacillaceae pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 iECO103_1326.ECO103_1444,iECSF_1327.ECSF_1264,iSFV_1184.SFV_1294,iSF_1195.SF1285,iSFxv_1172.SFxv_1457,iS_1188.S1368,ic_1306.c1750 Bacteria 1TPPH@1239,3F47Y@33958,4HAJ2@91061,COG0284@1,COG0284@2 NA|NA|NA F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) KIAJIJGH_02013 334390.LAF_0048 3.8e-116 424.1 Lactobacillaceae pyrE 2.4.2.10,4.1.1.23 ko:K00762,ko:K01591,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00051 R00965,R01870,R08231 RC00063,RC00409,RC00611 ko00000,ko00001,ko00002,ko01000 iYO844.BSU15560 Bacteria 1V1BZ@1239,3F487@33958,4HFV7@91061,COG0461@1,COG0461@2 NA|NA|NA F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) KIAJIJGH_02014 575594.ACOH01000002_gene1015 4.4e-34 151.4 Bacteria gntT Bacteria COG2610@1,COG2610@2 NA|NA|NA EG gluconate transmembrane transporter activity KIAJIJGH_02015 1203076.CAKF01000023_gene659 6.9e-47 193.4 Lactobacillaceae Bacteria 1VFXH@1239,2DNYJ@1,32ZT4@2,3F6B5@33958,4HPEG@91061 NA|NA|NA KIAJIJGH_02016 334390.LAF_0051 1.9e-273 948.0 Lactobacillaceae tagE3 2.4.1.52 ko:K00712 ko00000,ko01000,ko01003 GT4 Bacteria 1V09I@1239,3FBDH@33958,4HDDD@91061,COG0438@1,COG0438@2 NA|NA|NA M Glycosyl transferases group 1 KIAJIJGH_02017 334390.LAF_0052 1.3e-260 905.2 Lactobacillaceae tagE2 2.4.1.52 ko:K00712 ko00000,ko01000,ko01003 GT4 Bacteria 1VSNK@1239,3F4VP@33958,4HU8G@91061,COG0438@1,COG0438@2 NA|NA|NA M Poly(Glycerol-phosphate) alpha-glucosyltransferase KIAJIJGH_02018 334390.LAF_0053 1e-148 532.7 Lactobacillaceae metQ1 ko:K02073 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TQAS@1239,3F3WP@33958,4HCTA@91061,COG1464@1,COG1464@2 NA|NA|NA P Belongs to the nlpA lipoprotein family KIAJIJGH_02019 334390.LAF_0054 6.1e-191 673.3 Lactobacillaceae metN ko:K02071 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TPPN@1239,3F3U5@33958,4H9VX@91061,COG1135@1,COG1135@2 NA|NA|NA P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system KIAJIJGH_02020 334390.LAF_0055 1.2e-97 362.8 Lactobacillaceae metI ko:K02072 ko02010,map02010 M00238 ko00000,ko00001,ko00002,ko02000 3.A.1.24 Bacteria 1TRSY@1239,3F48A@33958,4HBEV@91061,COG2011@1,COG2011@2 NA|NA|NA P ABC transporter permease KIAJIJGH_02021 334390.LAF_0056 2.2e-218 764.6 Lactobacillaceae argE 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPMJ@1239,3F3N9@33958,4HB39@91061,COG0624@1,COG0624@2 NA|NA|NA E succinyl-diaminopimelate desuccinylase KIAJIJGH_02022 334390.LAF_0056 7.9e-32 142.5 Lactobacillaceae argE 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPMJ@1239,3F3N9@33958,4HB39@91061,COG0624@1,COG0624@2 NA|NA|NA E succinyl-diaminopimelate desuccinylase KIAJIJGH_02023 334390.LAF_0057 9.9e-245 852.4 Lactobacillaceae rumA 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 ko00000,ko01000,ko03009,ko03016 Bacteria 1TP4H@1239,3F4GQ@33958,4HA6M@91061,COG2265@1,COG2265@2 NA|NA|NA J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family KIAJIJGH_02024 1203076.CAKF01000021_gene1391 1.6e-196 692.2 Lactobacillaceae brnQ GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903785,GO:1903825,GO:1905039 ko:K03311 ko00000 2.A.26 Bacteria 1TQIS@1239,3F3KC@33958,4HAKA@91061,COG1114@1,COG1114@2 NA|NA|NA U Component of the transport system for branched-chain amino acids KIAJIJGH_02025 1302286.BAOT01000060_gene2014 6.3e-123 447.2 Lactobacillaceae iolS ko:K06607 ko00000,ko01000 Bacteria 1TPIY@1239,3F40K@33958,4HA4Q@91061,COG0667@1,COG0667@2 NA|NA|NA C Aldo keto reductase KIAJIJGH_02026 334390.LAF_0060 2.4e-245 854.4 Lactobacillaceae dltD ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 ko00000,ko00001,ko00002,ko01504 Bacteria 1TSZU@1239,3F3WE@33958,4HC3H@91061,COG3966@1,COG3966@2 NA|NA|NA M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) KIAJIJGH_02027 334390.LAF_0061 1.2e-35 155.2 Lactobacillaceae dltC GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K02078,ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1VFQI@1239,3F7Q1@33958,4HNIH@91061,COG0236@1,COG0236@2 NA|NA|NA J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall KIAJIJGH_02028 334390.LAF_0062 7e-239 832.8 Lactobacillaceae dltB ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 ko00000,ko00001,ko00002,ko01504 Bacteria 1TP52@1239,3F4KK@33958,4HBQG@91061,COG1696@1,COG1696@2 NA|NA|NA M MBOAT, membrane-bound O-acyltransferase family KIAJIJGH_02029 334390.LAF_0063 8.3e-298 1028.9 Lactobacillaceae dltA GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016208,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0022857,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 Bacteria 1TPTH@1239,3F49R@33958,4HAHU@91061,COG1020@1,COG1020@2 NA|NA|NA H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall KIAJIJGH_02031 334390.LAF_0064 2.9e-57 227.6 Lactobacillaceae sbcD ko:K03547 ko00000,ko03400 Bacteria 1TQY6@1239,3F4A9@33958,4HAKB@91061,COG0420@1,COG0420@2 NA|NA|NA L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity KIAJIJGH_02032 334390.LAF_0065 0.0 1550.0 Lactobacillaceae sbcC ko:K03546 ko00000,ko03400 Bacteria 1TPCS@1239,3F3TE@33958,4H9Q3@91061,COG0419@1,COG0419@2 NA|NA|NA L Putative exonuclease SbcCD, C subunit KIAJIJGH_02033 334390.LAF_0066 4.1e-229 800.4 Lactobacillaceae serS GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 iAF987.Gmet_3528,iSDY_1059.SDY_2368 Bacteria 1TP4W@1239,3F3M6@33958,4H9Y4@91061,COG0172@1,COG0172@2 NA|NA|NA J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) KIAJIJGH_02035 334390.LAF_0067 1.2e-188 665.6 Lactobacillaceae trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Bacteria 1TPY7@1239,3F3V6@33958,4HA1K@91061,COG0180@1,COG0180@2 NA|NA|NA J Belongs to the class-I aminoacyl-tRNA synthetase family KIAJIJGH_02037 334390.LAF_0069 4.4e-224 783.9 Lactobacillaceae glnP ko:K02029,ko:K02030 M00236 ko00000,ko00002,ko02000 3.A.1.3 Bacteria 1TQUG@1239,3F4HA@33958,4HAJ5@91061,COG0765@1,COG0765@2,COG0834@1,COG0834@2 NA|NA|NA P ABC transporter KIAJIJGH_02038 334390.LAF_0070 1e-136 492.7 Lactobacillaceae glnQ 3.6.3.21 ko:K02028,ko:K10038 ko02010,map02010 M00227,M00236 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.2 Bacteria 1TNYD@1239,3F3QQ@33958,4H9WY@91061,COG1126@1,COG1126@2 NA|NA|NA E ABC transporter, ATP-binding protein KIAJIJGH_02039 334390.LAF_0071 3.2e-248 864.0 Lactobacillaceae cycA GO:0001761,GO:0001762,GO:0003333,GO:0003674,GO:0005215,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015180,GO:0015187,GO:0015238,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015808,GO:0015816,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0022858,GO:0022889,GO:0032328,GO:0032329,GO:0034220,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0042940,GO:0042941,GO:0042942,GO:0042943,GO:0042944,GO:0042945,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 ko:K03293,ko:K11737 ko00000,ko02000 2.A.3.1,2.A.3.1.7 iECO111_1330.ECO111_5093,iECO26_1355.ECO26_5376,iEcHS_1320.EcHS_A4458,iSbBS512_1146.SbBS512_E4749,iYL1228.KPN_04601 Bacteria 1TP97@1239,3F3YD@33958,4H9QX@91061,COG1113@1,COG1113@2 NA|NA|NA E Amino acid permease KIAJIJGH_02040 334390.LAF_0141 4.7e-90 337.0 Lactobacillaceae 2.4.2.6 ko:K08728 ko00240,map00240 R02806 RC00063 ko00000,ko00001,ko01000 Bacteria 1VETR@1239,3F6C3@33958,4HNTN@91061,COG3613@1,COG3613@2 NA|NA|NA F nucleoside 2-deoxyribosyltransferase KIAJIJGH_02041 1423814.HMPREF0549_0026 7.1e-29 133.7 Lactobacillaceae ko:K18926 M00715 ko00000,ko00002,ko02000 2.A.1.3.30 Bacteria 1UYQB@1239,3F3NG@33958,4HE3Y@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily KIAJIJGH_02042 334390.LAF_0140 0.0 1186.8 Lactobacillaceae copA 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 Bacteria 1TP5S@1239,3F4IX@33958,4HAI0@91061,COG2217@1,COG2217@2 NA|NA|NA P P-type ATPase KIAJIJGH_02043 334390.LAF_0139 3.3e-52 210.7 Lactobacillaceae silP 1.9.3.1,3.6.3.54 ko:K02275,ko:K17686 ko00190,ko01100,ko01524,ko04016,map00190,map01100,map01524,map04016 M00155 R00081,R00086 RC00002,RC00016 ko00000,ko00001,ko00002,ko01000 3.A.3.5,3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 1W06G@1239,3F7FA@33958,4HZAG@91061,COG4633@1,COG4633@2 NA|NA|NA S Cupredoxin-like domain KIAJIJGH_02044 334390.LAF_0138 1.1e-46 192.6 Lactobacillaceae silP 1.9.3.1,3.6.3.54 ko:K02275,ko:K17686 ko00190,ko01100,ko01524,ko04016,map00190,map01100,map01524,map04016 M00155 R00081,R00086 RC00002,RC00016 ko00000,ko00001,ko00002,ko01000 3.A.3.5,3.D.4.2,3.D.4.4,3.D.4.6 Bacteria 1TQ02@1239,3FBQA@33958,4IRVT@91061,COG4633@1,COG4633@2 NA|NA|NA S Cupredoxin-like domain KIAJIJGH_02045 334390.LAF_0137 6.4e-35 152.9 Lactobacillaceae Bacteria 1U59P@1239,29NNF@1,309KD@2,3F5AE@33958,4IF13@91061 NA|NA|NA KIAJIJGH_02046 334390.LAF_0137 4.5e-161 573.9 Lactobacillaceae Bacteria 1U59P@1239,29NNF@1,309KD@2,3F5AE@33958,4IF13@91061 NA|NA|NA KIAJIJGH_02047 334390.LAF_0136 2.3e-223 781.2 Lactobacillaceae patA 2.6.1.1,2.6.1.57 ko:K00812,ko:K00832,ko:K00841,ko:K10907 ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00024,M00025,M00034,M00040,M00525 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R04467,R05052,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 Bacteria 1TP0J@1239,3F3MX@33958,4HA13@91061,COG0436@1,COG0436@2 NA|NA|NA E Aminotransferase KIAJIJGH_02048 334390.LAF_0135 4.7e-131 473.8 Lactobacillaceae gpmA GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Bacteria 1TQFP@1239,3F3SK@33958,4HAW7@91061,COG0588@1,COG0588@2 NA|NA|NA G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate KIAJIJGH_02049 334390.LAF_0132 4.5e-241 840.1 Lactobacillaceae purD 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS05245,iYO844.BSU06530 Bacteria 1UHN9@1239,3F4Z8@33958,4HA70@91061,COG0151@1,COG0151@2 NA|NA|NA F Belongs to the GARS family KIAJIJGH_02050 1423814.HMPREF0549_0015 6.5e-38 162.9 Lactobacillaceae tdh 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPWP@1239,3F3WG@33958,4HABC@91061,COG1063@1,COG1063@2 NA|NA|NA C Zinc-binding dehydrogenase KIAJIJGH_02051 908339.HMPREF9265_1723 2.5e-104 384.8 Lactobacillaceae tdh 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 Bacteria 1TPWP@1239,3FC44@33958,4HVQZ@91061,COG1063@1,COG1063@2 NA|NA|NA E Alcohol dehydrogenase GroES-like domain KIAJIJGH_02052 525309.HMPREF0494_0536 1.1e-30 139.0 Lactobacillaceae ko:K15383 ko00000,ko02000 9.A.58.2 Bacteria 1VBI9@1239,3F7IR@33958,4HMY5@91061,COG4095@1,COG4095@2 NA|NA|NA S Sugar efflux transporter for intercellular exchange KIAJIJGH_02053 1133569.AHYZ01000032_gene816 4.7e-32 143.7 Lactobacillaceae higA ko:K21498 ko00000,ko02048 Bacteria 1VCFB@1239,3F7RE@33958,4IG6K@91061,COG3093@1,COG3093@2 NA|NA|NA K Helix-turn-helix XRE-family like proteins KIAJIJGH_02054 405566.lhv_1984 3.6e-193 680.6 Lactobacillaceae yegU Bacteria 1U2AQ@1239,3F4WI@33958,4HIXT@91061,COG1397@1,COG1397@2 NA|NA|NA O ADP-ribosylglycohydrolase KIAJIJGH_02055 405566.lhv_1985 1.1e-250 872.1 Bacilli ko:K03457 ko00000 2.A.39 Bacteria 1TRAH@1239,4IRPE@91061,COG1457@1,COG1457@2 NA|NA|NA F Belongs to the purine-cytosine permease (2.A.39) family KIAJIJGH_02056 405566.lhv_1986 5.2e-167 593.6 Lactobacillaceae Bacteria 1UIWH@1239,3F5HW@33958,4HI23@91061,COG0524@1,COG0524@2 NA|NA|NA G Belongs to the carbohydrate kinase PfkB family KIAJIJGH_02057 334390.LAF_0084 3.5e-156 558.1 Lactobacillaceae brpA Bacteria 1TR1B@1239,3F3MQ@33958,4HA09@91061,COG1316@1,COG1316@2 NA|NA|NA K Cell envelope-like function transcriptional attenuator common domain protein KIAJIJGH_02060 334390.LAF_0131 6.4e-218 763.1 Lactobacillaceae purH GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 iJN678.purH Bacteria 1TPQ5@1239,3F4FD@33958,4H9YY@91061,COG0138@1,COG0138@2 NA|NA|NA F Bifunctional purine biosynthesis protein PurH KIAJIJGH_02061 334390.LAF_1226 2.6e-135 488.0 Lactobacillaceae pstB 3.6.3.27 ko:K02036 ko02010,map02010 M00222 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 iLJ478.TM1261 Bacteria 1TP1M@1239,3F3SY@33958,4HAB1@91061,COG1117@1,COG1117@2 NA|NA|NA P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system KIAJIJGH_02062 334390.LAF_1225 1.8e-122 445.3 Lactobacillaceae phoU ko:K02039 ko00000 Bacteria 1URN3@1239,3F46W@33958,4HEU9@91061,COG0704@1,COG0704@2 NA|NA|NA P Plays a role in the regulation of phosphate uptake KIAJIJGH_02063 334390.LAF_1224 2.9e-44 184.1 Lactobacillaceae rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02959 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Bacteria 1VA0X@1239,3F6VV@33958,4HKNN@91061,COG0228@1,COG0228@2 NA|NA|NA J Belongs to the bacterial ribosomal protein bS16 family KIAJIJGH_02064 334390.LAF_1223 5.4e-40 169.9 Lactobacillaceae ylqC ko:K06960 ko00000 Bacteria 1VEG7@1239,3F829@33958,4HNX0@91061,COG1837@1,COG1837@2 NA|NA|NA S Belongs to the UPF0109 family KIAJIJGH_02065 334390.LAF_1222 8e-88 329.7 Lactobacillaceae rimM GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 ko:K02860 ko00000,ko03009 Bacteria 1V6HD@1239,3F74P@33958,4HH3H@91061,COG0806@1,COG0806@2 NA|NA|NA J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes KIAJIJGH_02066 334390.LAF_1221 2.9e-142 511.1 Lactobacillaceae trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 ko:K00554,ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R00597,R05637 RC00002,RC00003,RC00334,RC01440 ko00000,ko00001,ko00002,ko01000,ko03016 Bacteria 1TPBV@1239,3F3NP@33958,4HBFV@91061,COG0336@1,COG0336@2 NA|NA|NA J Belongs to the RNA methyltransferase TrmD family KIAJIJGH_02067 334390.LAF_1220 7.5e-261 906.0 Lactobacillaceae yfnA ko:K03294 ko00000 2.A.3.2 Bacteria 1TQ4K@1239,3F3QY@33958,4HA66@91061,COG0531@1,COG0531@2 NA|NA|NA E Amino Acid KIAJIJGH_02068 334390.LAF_1219 2.1e-58 231.5 Lactobacillaceae rplS GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 ko:K02884 ko03010,map03010 M00178 br01610,ko00000,ko00001,ko00002,ko03011 Bacteria 1V6FT@1239,3F6K4@33958,4HIK3@91061,COG0335@1,COG0335@2 NA|NA|NA J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site KIAJIJGH_02069 334390.LAF_0742 3e-189 667.5 Lactobacillaceae panE1 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 Bacteria 1TSZ1@1239,3F455@33958,4HB4T@91061,COG1893@1,COG1893@2 NA|NA|NA H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid KIAJIJGH_02070 334390.LAF_0743 4.9e-52 210.3 Lactobacillaceae ypaA ko:K08987 ko00000 Bacteria 1VAVU@1239,3F7NA@33958,4HQHN@91061,COG3759@1,COG3759@2 NA|NA|NA S Protein of unknown function (DUF1304) KIAJIJGH_02071 908339.HMPREF9265_1979 1.1e-96 359.4 Lactobacillaceae ko:K06889 ko00000 Bacteria 1TQYU@1239,3F43H@33958,4HC4H@91061,COG1073@1,COG1073@2 NA|NA|NA D Alpha beta KIAJIJGH_02072 334390.LAF_0737 1.7e-249 868.2 Lactobacillaceae Bacteria 1TPRN@1239,3F3XY@33958,4H9VV@91061,COG0477@1,COG2814@2 NA|NA|NA EGP Major facilitator Superfamily KIAJIJGH_02073 1133569.AHYZ01000044_gene1466 2.6e-142 511.9 Lactobacillaceae leuA 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 iSB619.SA_RS10690,iYO844.BSU28280 Bacteria 1TP4Y@1239,3F581@33958,4HA6E@91061,COG0119@1,COG0119@2 NA|NA|NA E Belongs to the alpha-IPM synthase homocitrate synthase family # 1876 queries scanned # Total time (seconds): 4.92079615593 # Rate: 381.24 q/s